LOCUS       DADGHT010000001        83609 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.001, whole genome shotgun sequence.
ACCESSION   DADGHT010000001 DADGHT010000000
VERSION     DADGHT010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 83609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.001"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(582..1147)
                     /locus_tag="JX887_000001"
                     /pseudo
     CDS             complement(582..1147)
                     /locus_tag="JX887_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1326..1982)
                     /locus_tag="JX887_000002"
     CDS             complement(1326..1982)
                     /locus_tag="JX887_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256025.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(2550..3485)
                     /gene="whiA"
                     /locus_tag="JX887_000003"
     CDS             complement(2550..3485)
                     /gene="whiA"
                     /locus_tag="JX887_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAX1256026.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(3519..4517)
                     /locus_tag="JX887_000004"
     CDS             complement(3519..4517)
                     /locus_tag="JX887_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAX1256027.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(4514..5398)
                     /gene="rapZ"
                     /locus_tag="JX887_000005"
     CDS             complement(4514..5398)
                     /gene="rapZ"
                     /locus_tag="JX887_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAX1256028.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(5533..6264)
                     /locus_tag="JX887_000006"
     CDS             complement(5533..6264)
                     /locus_tag="JX887_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAX1256029.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(6268..7533)
                     /locus_tag="JX887_000007"
     CDS             complement(6268..7533)
                     /locus_tag="JX887_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAX1256030.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(7796..10612)
                     /gene="uvrA"
                     /locus_tag="JX887_000008"
     CDS             complement(7796..10612)
                     /gene="uvrA"
                     /locus_tag="JX887_000008"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAX1256031.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(10622..12616)
                     /gene="uvrB"
                     /locus_tag="JX887_000009"
     CDS             complement(10622..12616)
                     /gene="uvrB"
                     /locus_tag="JX887_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAX1256032.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            12875..14377
                     /locus_tag="JX887_000010"
     CDS             12875..14377
                     /locus_tag="JX887_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1256033.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            14379..15116
                     /locus_tag="JX887_000011"
     CDS             14379..15116
                     /locus_tag="JX887_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAX1256034.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(15161..15334)
                     /locus_tag="JX887_000012"
     CDS             complement(15161..15334)
                     /locus_tag="JX887_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAX1256035.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            15310..15975
                     /locus_tag="JX887_000013"
     CDS             15310..15975
                     /locus_tag="JX887_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar diacid utilization regulator"
                     /protein_id="HAX1256036.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            complement(16057..17223)
                     /gene="dnaJ"
                     /locus_tag="JX887_000014"
     CDS             complement(16057..17223)
                     /gene="dnaJ"
                     /locus_tag="JX887_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAX1256037.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(17374..19203)
                     /gene="dnaK"
                     /locus_tag="JX887_000015"
     CDS             complement(17374..19203)
                     /gene="dnaK"
                     /locus_tag="JX887_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAX1256038.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(19254..19817)
                     /gene="grpE"
                     /locus_tag="JX887_000016"
     CDS             complement(19254..19817)
                     /gene="grpE"
                     /locus_tag="JX887_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAX1256039.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(19911..20954)
                     /gene="hrcA"
                     /locus_tag="JX887_000017"
     CDS             complement(19911..20954)
                     /gene="hrcA"
                     /locus_tag="JX887_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAX1256040.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(21188..22354)
                     /locus_tag="JX887_000018"
     CDS             complement(21188..22354)
                     /locus_tag="JX887_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAX1256041.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(22370..22597)
                     /locus_tag="JX887_000019"
     CDS             complement(22370..22597)
                     /locus_tag="JX887_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAX1256042.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            23081..23671
                     /locus_tag="JX887_000020"
     CDS             23081..23671
                     /locus_tag="JX887_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAX1256043.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            23861..24574
                     /locus_tag="JX887_000021"
     CDS             23861..24574
                     /locus_tag="JX887_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256044.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(24689..25699)
                     /locus_tag="JX887_000022"
     CDS             complement(24689..25699)
                     /locus_tag="JX887_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAX1256045.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(25736..26218)
                     /locus_tag="JX887_000023"
     CDS             complement(25736..26218)
                     /locus_tag="JX887_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAX1256046.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            26368..26736
                     /locus_tag="JX887_000024"
     CDS             26368..26736
                     /locus_tag="JX887_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAX1256047.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            27201..27653
                     /locus_tag="JX887_000025"
     CDS             27201..27653
                     /locus_tag="JX887_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1256048.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(27777..28628)
                     /locus_tag="JX887_000026"
     CDS             complement(27777..28628)
                     /locus_tag="JX887_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAX1256049.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(28641..29426)
                     /locus_tag="JX887_000027"
     CDS             complement(28641..29426)
                     /locus_tag="JX887_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1256050.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            complement(29778..30719)
                     /gene="ribF"
                     /locus_tag="JX887_000028"
     CDS             complement(29778..30719)
                     /gene="ribF"
                     /locus_tag="JX887_000028"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAX1256051.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(30723..31646)
                     /gene="truB"
                     /locus_tag="JX887_000029"
     CDS             complement(30723..31646)
                     /gene="truB"
                     /locus_tag="JX887_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAX1256052.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(32014..34376)
                     /locus_tag="JX887_000030"
                     /pseudo
     CDS             complement(32014..34376)
                     /locus_tag="JX887_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            34824..34997
                     /locus_tag="JX887_000031"
     CDS             34824..34997
                     /locus_tag="JX887_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1256053.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(35154..35501)
                     /gene="rbfA"
                     /locus_tag="JX887_000032"
     CDS             complement(35154..35501)
                     /gene="rbfA"
                     /locus_tag="JX887_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAX1256054.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(35528..37834)
                     /gene="infB"
                     /locus_tag="JX887_000033"
     CDS             complement(35528..37834)
                     /gene="infB"
                     /locus_tag="JX887_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAX1256055.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(37847..38158)
                     /locus_tag="JX887_000034"
     CDS             complement(37847..38158)
                     /locus_tag="JX887_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAX1256056.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(38155..38448)
                     /locus_tag="JX887_000035"
     CDS             complement(38155..38448)
                     /locus_tag="JX887_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAX1256057.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(38470..39645)
                     /gene="nusA"
                     /locus_tag="JX887_000036"
     CDS             complement(38470..39645)
                     /gene="nusA"
                     /locus_tag="JX887_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAX1256058.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(39668..40141)
                     /gene="rimP"
                     /locus_tag="JX887_000037"
     CDS             complement(39668..40141)
                     /gene="rimP"
                     /locus_tag="JX887_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAX1256059.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(40286..44644)
                     /locus_tag="JX887_000038"
     CDS             complement(40286..44644)
                     /locus_tag="JX887_000038"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAX1256060.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(44856..46565)
                     /locus_tag="JX887_000039"
     CDS             complement(44856..46565)
                     /locus_tag="JX887_000039"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAX1256061.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(46633..47901)
                     /gene="rseP"
                     /locus_tag="JX887_000040"
     CDS             complement(46633..47901)
                     /gene="rseP"
                     /locus_tag="JX887_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAX1256062.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(48062..48862)
                     /locus_tag="JX887_000041"
     CDS             complement(48062..48862)
                     /locus_tag="JX887_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAX1256063.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(48859..49671)
                     /locus_tag="JX887_000042"
     CDS             complement(48859..49671)
                     /locus_tag="JX887_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAX1256064.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(49866..50423)
                     /gene="frr"
                     /locus_tag="JX887_000043"
     CDS             complement(49866..50423)
                     /gene="frr"
                     /locus_tag="JX887_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAX1256065.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(50426..51148)
                     /locus_tag="JX887_000044"
     CDS             complement(50426..51148)
                     /locus_tag="JX887_000044"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAX1256066.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(51284..52165)
                     /locus_tag="JX887_000045"
     CDS             complement(51284..52165)
                     /locus_tag="JX887_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAX1256067.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(52264..53046)
                     /gene="rpsB"
                     /locus_tag="JX887_000046"
     CDS             complement(52264..53046)
                     /gene="rpsB"
                     /locus_tag="JX887_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAX1256068.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            53405..53884
                     /locus_tag="JX887_000047"
     CDS             53405..53884
                     /locus_tag="JX887_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAX1256069.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            54101..55192
                     /gene="phnW"
                     /locus_tag="JX887_000048"
     CDS             54101..55192
                     /gene="phnW"
                     /locus_tag="JX887_000048"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAX1256070.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            55185..55313
                     /locus_tag="JX887_000049"
     CDS             55185..55313
                     /locus_tag="JX887_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAX1256071.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            55317..55862
                     /locus_tag="JX887_000050"
     CDS             55317..55862
                     /locus_tag="JX887_000050"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAX1256072.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(56316..58007)
                     /locus_tag="JX887_000051"
     CDS             complement(56316..58007)
                     /locus_tag="JX887_000051"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAX1256073.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(58427..59374)
                     /gene="arcC"
                     /locus_tag="JX887_000052"
     CDS             complement(58427..59374)
                     /gene="arcC"
                     /locus_tag="JX887_000052"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAX1256074.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(59489..60508)
                     /gene="argF"
                     /locus_tag="JX887_000053"
     CDS             complement(59489..60508)
                     /gene="argF"
                     /locus_tag="JX887_000053"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAX1256075.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(60599..61828)
                     /gene="arcA"
                     /locus_tag="JX887_000054"
     CDS             complement(60599..61828)
                     /gene="arcA"
                     /locus_tag="JX887_000054"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAX1256076.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            62289..62990
                     /locus_tag="JX887_000055"
     CDS             62289..62990
                     /locus_tag="JX887_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAX1256077.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(63599..64615)
                     /gene="tsaD"
                     /locus_tag="JX887_000056"
     CDS             complement(63599..64615)
                     /gene="tsaD"
                     /locus_tag="JX887_000056"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAX1256078.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(64612..65076)
                     /gene="rimI"
                     /locus_tag="JX887_000057"
     CDS             complement(64612..65076)
                     /gene="rimI"
                     /locus_tag="JX887_000057"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAX1256079.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(65083..65625)
                     /gene="rimI"
                     /locus_tag="JX887_000058"
     CDS             complement(65083..65625)
                     /gene="rimI"
                     /locus_tag="JX887_000058"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAX1256080.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(65609..66433)
                     /gene="tsaB"
                     /locus_tag="JX887_000059"
     CDS             complement(65609..66433)
                     /gene="tsaB"
                     /locus_tag="JX887_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAX1256081.1"
                     /translation="MYYCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDNIIVPMFDARRKNVYAGAY
                     RWKENRLETVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFSEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            complement(66522..67502)
                     /locus_tag="JX887_000060"
     CDS             complement(66522..67502)
                     /locus_tag="JX887_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAX1256082.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(67526..69010)
                     /gene="galT"
                     /locus_tag="JX887_000061"
     CDS             complement(67526..69010)
                     /gene="galT"
                     /locus_tag="JX887_000061"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAX1256083.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(69022..70011)
                     /gene="galE"
                     /locus_tag="JX887_000062"
     CDS             complement(69022..70011)
                     /gene="galE"
                     /locus_tag="JX887_000062"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAX1256084.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            70259..70426
                     /locus_tag="JX887_000063"
     CDS             70259..70426
                     /locus_tag="JX887_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAX1256085.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(70488..72299)
                     /locus_tag="JX887_000064"
     CDS             complement(70488..72299)
                     /locus_tag="JX887_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAX1256086.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(72296..72661)
                     /locus_tag="JX887_000065"
     CDS             complement(72296..72661)
                     /locus_tag="JX887_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAX1256087.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(72824..73219)
                     /locus_tag="JX887_000066"
     CDS             complement(72824..73219)
                     /locus_tag="JX887_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAX1256088.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(73237..74199)
                     /locus_tag="JX887_000067"
     CDS             complement(73237..74199)
                     /locus_tag="JX887_000067"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAX1256089.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(74199..74411)
                     /locus_tag="JX887_000068"
     CDS             complement(74199..74411)
                     /locus_tag="JX887_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAX1256090.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(74432..75130)
                     /locus_tag="JX887_000069"
     CDS             complement(74432..75130)
                     /locus_tag="JX887_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAX1256091.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(75150..75692)
                     /locus_tag="JX887_000070"
     CDS             complement(75150..75692)
                     /locus_tag="JX887_000070"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAX1256092.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(75824..76828)
                     /locus_tag="JX887_000071"
     CDS             complement(75824..76828)
                     /locus_tag="JX887_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAX1256093.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(76825..77814)
                     /locus_tag="JX887_000072"
     CDS             complement(76825..77814)
                     /locus_tag="JX887_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAX1256094.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(77811..78617)
                     /locus_tag="JX887_000073"
     CDS             complement(77811..78617)
                     /locus_tag="JX887_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256095.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            78783..79739
                     /locus_tag="JX887_000074"
     CDS             78783..79739
                     /locus_tag="JX887_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1256096.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(79816..80334)
                     /locus_tag="JX887_000075"
     CDS             complement(79816..80334)
                     /locus_tag="JX887_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAX1256097.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(80422..80571)
                     /gene="rpmG"
                     /locus_tag="JX887_000076"
     CDS             complement(80422..80571)
                     /gene="rpmG"
                     /locus_tag="JX887_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAX1256098.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            80799..81245
                     /locus_tag="JX887_000077"
     CDS             80799..81245
                     /locus_tag="JX887_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAX1256099.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(81440..83335)
                     /gene="asnB"
                     /locus_tag="JX887_000078"
     CDS             complement(81440..83335)
                     /gene="asnB"
                     /locus_tag="JX887_000078"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAX1256100.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT        23706 a        17830 c        14420 g        27653 t
ORIGIN      
        1 ccagcctcct tattccgaat aaatggtgtc caaaagcttg catctgccag attatctcat
       61 ttcttatgac aagctgagca aattatctcc accaaataat ttattcatat ttttgacttg
      121 cgcatactaa ctaattctta aattttcata caaaatttct caaattccct taacgagtaa
      181 tatttatgta cggtgattca cactagtatc ccaatcactt tttaagttat cccgatttca
      241 attctacttc aaaaatagtt gcttttatgt atgctgttag ttgattagat ggtcgtttgt
      301 tgagctaggt cgtttatttt aaacaagttg tttctttagc ttatacctat ctcgtctacc
      361 aaacgcaaga tggcaaacac aaatgcatac gcatctgtat ttgccacttt gattcgtata
      421 aagctaacaa ctcctaactc ctctcattta atagttgctc tcttttttat tcagatacat
      481 ttttgctgat cacagcctag tatttcaatg gttttgaaca ctaaaccaaa ttgttccatt
      541 acaacattca ctggctgatg aaatggatta atagatttcg attattcaaa gcgattttct
      601 attggtggat tgtgttccca actaacaaga cggattccaa agtcattata taactcttca
      661 agagttaacc ctttcctgtt cccaatagat gtatctctcc cacgctcgat ataaaatatg
      721 gagtttcgaa tgccaagacc tggcaaatct ttccttgtta cagttacact gctactaact
      781 tccccatata aaatccagct cctccaaaat gataatatat ttttcgacca tcatctaact
      841 catgtaacaa taattgttgt gccctcttgt cactcgccaa atgcaaacgc cacgtgcgat
      901 accatgccat gctacctgca tctgcagaaa atccatcaaa taatgcaaca attgtatctt
      961 ctatcacaat cctttcccca tctacttcat attctaatct aaaatcaaac tcccctcggg
     1021 taatcgcagg tcttggtggc ttaggaccca atattattct acttaaaacc gcattcgttc
     1081 ccagatgaaa cacagctata acaacaataa tgattaatat tttgtttcta tttgataaat
     1141 ttctcattat tcgcaaatca cctctacatt ctcacatact agttcgtaat actcctttaa
     1201 tatcaaaata tctactgatc gtaataatat tcgctatgaa ttcctactac tcgtataaga
     1261 aaggccaaat catcagcttt tacttgctga tgatttggct tgtttctatt tatcgtaatt
     1321 gttttctaat caccaaaatt gttaacaatc ggttcagata tttcccaatt cactagcctt
     1381 atattatatt gatttaacaa ttcttcttca tttattgtat tttgatcaag cggaccaaat
     1441 tgttctaata attctttgtc atgtaaaata tcccttctag taatgcctct ttccctttca
     1501 atgaaagaag cactaggaaa agtatgatta taaccattca acctatctcc catgtaataa
     1561 ttagcaggtc ctggaaaata aaatatttgc ttattatcac taacttctaa cagcaacact
     1621 aaatcttctc cgctggctaa acgacttgtc catctacgat atctccctat gccttcgttc
     1681 attccaaatc catcaaattc aactattaac gtgtcttcta tcacatgtaa ttcttcattc
     1741 aattcatact caagtctaaa aggaaattct ccatatgtaa tctctggcaa tggtggtgct
     1801 ggagttctcc aaataaatac aataactgtg aatagaaaaa atccaacgat cgatataaat
     1861 gttatgagac ctgctcgaag taaaacccga tataataaaa atgctgtatt tcgctttgct
     1921 atatctagaa aaataaaaag tactgcaatc ataatgatag taaaagttgt aaaaaaacgc
     1981 atttttgccc tccctttata aacatcgatt ctcaaattct aaaccaaatc ttggtagttc
     2041 aagttcaggt ataacgtatt ccaaccatac atctcaatta ctatttatga acttatgatt
     2101 atcactgaat aaatcactcc atccccttgt taaaacttct acattaatta cacctggttg
     2161 ttttcgacta gctaatccaa tgaacttatc aaccatcctt atccaccaac cacgagaatc
     2221 ttgaccagaa gtaagaagag cagttctcaa ggatgatcga gcagttcctt ccagtttttt
     2281 aattaatcag gccagttata gataaatact tgatcttatc tatatcagga cttctatatt
     2341 aagcaaaaat ttatgtacaa aactaaaatc ttcattcagt tgtctccccg ctttttatac
     2401 gattgtatta aaaacaatag aagcctttcc aaattatgtt actccagtaa agatggaatt
     2461 atagtttgac ggaagaaaag caagtataac ttttaaaaaa aactgataca ttcgcatctc
     2521 ctgcttcatg tatcagtttt ttctttggat taaactgctt cttcacgcag tttttccgca
     2581 aattcattta ttttgcgaat tcggtgatta attcccgatt ttgatatcgc acctgaggga
     2641 atcatttccc ctaattcttt caagctgacc tctggatgtt gaagccgaag ttctgcgatt
     2701 tcctgaagtt tttcaggaag ggcatgtaga ccgacctttg cttcgatcaa ttcgatgttt
     2761 tcgatttgtt tagaagccgc atcaatcgtc ttgttcagat ttgctgtctc acaattgact
     2821 agacgattga ccgaatttct catatcccgt acgattcgaa catcttcaaa tcggagcatt
     2881 gagttggttg caccaatcaa tgttaagaaa tcagcaattt tttctgctcc ttttaaataa
     2941 gaaatatagc cattgcgccg ttcaagcgtt cgagcatgta gaccgtaata atttaacata
     3001 tcgcaaatgt cttggttatg ctgttcataa atagaaaata tttccaaatg ataacggctc
     3061 gtttccggat tattgactga acctgaggcc ataaaagcac cacgtaagta agaacgcatt
     3121 ttttgcgaat ttcccataat ctcgtccgaa acgtgtccat tgaacatcat accatccatg
     3181 atatcaagat ccatcaacac atcttttgtg ccttgcttca accggacgat atagacattg
     3241 ttctttttta atttcatttt tttacgaacg agtagctcac ttcgtacctg ataatgatct
     3301 ttcaaaagag aatagatacg tctggcaatt gcagcatttt ctgtttggac gttcaaaata
     3361 aactgctggt tcacaatacc taaagagccg ttcattcgca gcaaagcagc taattccgct
     3421 ttcgcatgtt ctcgatgaac ttccaaacca gttagttctt tcttcacatc tgcagcaaat
     3481 gacatcctat tctcctcctt tctccaacaa taaattgctt aatattttga accgaaaact
     3541 aaacggaaca attcttctac tactttgtct ccatcgtgga agacaccacc atctttcaat
     3601 tccaaaaagt cggtggaaat cactcgacat ccttcatttc tcaatccgtt gaagtcgtgt
     3661 gcgacttgta ctagatactc atcatagatc tctgggtcca tataatcttc aggcactttt
     3721 tccgtattga ccaatactgt atcgataaaa ggctgattca aatgcttgtg taaaacacgt
     3781 atatgatcgg catctgtgaa atgttccgtt tccccttttt gggtcatgat attacagata
     3841 tagacggttt cagcagttgt cttgagcatt gcttcgccga tttctggtat cactaaattt
     3901 ggaaggatac tggtgaataa acttccgggt cccaaaacga ccatgtcggc gtccataatt
     3961 gctgaaacga cttttcgagc cgctttggct tcacttttat catttgtgtt gcagacatac
     4021 acacggtcaa tggttttacg gtcgatcgcg attttagatt ctcctactgc agtcgttccg
     4081 tctttaaaga cagcatgcaa ggtcaaagga gtttctgaag aaggataaac atgtccatct
     4141 acatgcatca tttttgctaa taattgaatc gcctcataag tgcttccccg catctcggaa
     4201 actgcggcaa tgatcagatt accgatcgta tgattggcta aaaactgatc ttcctttttg
     4261 aaacggtatt ggaaaatatc ttcatagaat tgtggcatat ccgataacgc cactaagaca
     4321 tttctcaagt caccaggagg agccatagcg atcgattctc tgattgcacc gctgcttccc
     4381 ccatcatctg caacagtcac tactgctgtg atatctgctc cttgatttcg caaacttttc
     4441 aggataactg gcagaccagt gccaccgccg accactacga tctttggttt tcttatccgg
     4501 taggttttca ttttcacgac cggttcaccg tctctttcct tttatccttg tcccgatgtg
     4561 tcacattgac tttatagttt ttccctaaag catttgccaa acgttcagtc aatgccacag
     4621 aacggtgttg accgcctgta cagccgattg caactgtcaa gctgcttttt ccttctttaa
     4681 tgtatccagg caatacagtt tccagaagat ccaaaaattt atggtagaat gattgcgttt
     4741 catcaaagga catcacataa tcatagactg gctgatcttt tccggtcaat ggtcttagtt
     4801 ccgggatata atgagggttg ggcaaaaaac gcacatccat cacaatatcc gaatcgatcg
     4861 gcaacccgta tttaaaacca aatgatacaa attcgatccg aaatccttgg tctccctttg
     4921 atttgaatga ctcattgatt ttttcacgta attgtcgtgg tgtcaatgtc gtcgtatcaa
     4981 tgatcacgga agcttgggct ttcaagtcgt ctagtatcgc ccgttcttta cgtatccctt
     5041 cagtgatcaa accgtccatc gccattggat gtgctcgtct tgtttctttg tagcgagcca
     5101 ctagttcttc gtctgaagca tctaaaaata agatagaagt gtcgatgaag ttcgtatttt
     5161 cgatttcgat cagcatgttt tggatttctt caaagaagga acgagaacgt aaatccactc
     5221 ctaaagccat ttttgtgact ttgcctgatt ctttgattaa ttcccagaat tttggaatca
     5281 atcgaggcgg catattatcg atacaaaaat agcccatatc ttcaaaactt tggatagcta
     5341 ctgttttccc tgcaccgctc atacctgtta tgatgactaa ttgcaaatta tctgtcataa
     5401 ttacgaactc ctctcacatt gtgcatagta aaattatatc attccgggcg tatcattacc
     5461 agttttcttt ttcttttaca aaaagatttg gaccaaatat cttttaggat atttgcccca
     5521 aatccaattt ttttactttt ccgatgctgt atccaatgcc ttgcttcttt cagctagcgc
     5581 tcgttcaatc gtccgatctg ctaaaataga ttgggcatcg atcactggat aatggttatc
     5641 ttcagcaaat tcatgcatca atgacaattc tgtgcaacct aagataactt tttcacagtt
     5701 taggcgctct accgcttctt ctaagatttc gtaatatagc tcttgattca aataatccga
     5761 ttccttgatc tcatgataga tcagataatt gattttttct tgaagaacag tatcaggaat
     5821 cactgtttcg aatccaagat ttttgacttc gcgttcatag attccagctt tcatacttcc
     5881 ttctgttcct agaatcgcta ctctccctgt cgtatgctga cggacaagtt catttgctgc
     5941 ttctcttggc atatgaagga taggaatatc cgttgccgct tgtaattctt caaaaaagta
     6001 gtgtgcggtg ttacaagtca acacaatgaa gttcggctgc aataaatttt gtttctcaat
     6061 atcatccagc agaaacggca ttggattttc ttctgatcga tctaaaatat aagctgtacg
     6121 atcaggaact gttgcatgat tgaataagac ataattcaaa tattcttgat cttttgtagc
     6181 tttcgttcgg tggttgatca agcgaacaaa actttctgtc gccatcgtgc ccattccgcc
     6241 taaaatactg aaaaaattct ccatgaacta gccttctttc acatgaaaat actttttgaa
     6301 tcttggaata tagttatgga acatatattt catcaacaac cagcgcttga ttgaccggtc
     6361 tttttcataa aacacagtag taccgtaacg attttctttg atcatttgct cagctagttt
     6421 tttgtcttca ttttcccgag catattctaa aaagattttt ttgggcacac ccatccataa
     6481 tcttgcttta tctgattgat tcgttccata ggtcgtttca acaaagggtt tgttaaacac
     6541 tcgatcttct gtgacgaaac gagccagatt caagccgttc aatgtcacaa agaaactgct
     6601 acgaccttgt ctcaaattga tttcaaataa tttatattct ccatctctag gatcatactt
     6661 catatcgaaa ttggcaaagc ctgtatattc gattttttcc aaaaatgcct taatggtttg
     6721 atagattttt tcgttataat ctggcatgat cacaacgtaa ttaccaatcg atgctggtgt
     6781 aggatcttct aacagtggat gaccaagaca catcatccga acttgatgat cttcatctac
     6841 atacgcattt agcacacgca tattactatc atcacccggg ataaaatctt gtacaatcat
     6901 ttcactttta taaccggctt cgtatatccg gcctaaaatt aaatcgaact cttctctagt
     6961 ctctaaaata aaagcttttt ttcttccttc aaattggaca gaaagatact ccacactgtt
     7021 tgcaggtttc aaagcaactg ggaattcaaa aggcaattcc tgttccaaat gtccatttac
     7081 taacatttct tctctgacga tcaatgtttt aggatacgga agatcatatt cttcacaaac
     7141 ttcataaaag cttactttat tgatcagtct ttcaaataaa gaataatcaa tatatggaca
     7201 gataaaatat tctgacagct cttgtttatg ttgggagatc aattctgcat atccatcacc
     7261 acaagcaatc aaaagatatt ttttactctt atcagaatat ctttcttttg ccaaacgaag
     7321 catcgtctcg ataaacacag ggtctttatc aaatcctgga ataacttcta cattgacaat
     7381 tttactgtag cgggtagggg ctaactgatc cgaagcatat gcttggcaga ttttgccgta
     7441 tgcttcatta aaagaacgtg ccataccata aacgttcatg tcgcttccta ataatatagg
     7501 gataaattct tcattttcaa tactgttcat cattatctct cacttactca taatctcttg
     7561 tttttctttt ccaactacac aaggaatatc ataccataaa gaaaaaagca atcaaaggaa
     7621 actcctccga ttgctcaatt cttttttgaa cggattgaac ttataggaag tttttgtcta
     7681 taccaatcag tgtagaaaga actaccatgt aatgattcta gaacactgat attaataaaa
     7741 caagcaaaaa ttcatttttt tatgtttttt taactatctc agctatctat cctctttata
     7801 ccattatttt tttcaaatag tgacctgtat aactttcttt tacgttaatg atttcttctg
     7861 gtgttccagt cgcaaggatc gttcctccac cttctccacc ttctggtcct aaatcaatga
     7921 tataatctgc tgttttgatt acatctagat tgtgttcaat cactaaaact gtgttaccag
     7981 catctactaa tctttgtaat acatgcaaca agcgggcgat gtcatcgcta tgaagtcctg
     8041 tcgttggttc atctagtata tagaaattct ttccattaga gattttgtgc aattcactgg
     8101 caagtttcat ccgttgtgcc tcaccaccgg acaatgtcgt tgctggttgc cccatcgtca
     8161 cataacctaa gccaacatca acaatcgttt gcagtttgcg atgaatcttt ggaatgtgct
     8221 tgaagaattc tacagcatct tctactgtca tttccaaaat atcagcaatg ctttttcctt
     8281 tgtaatgcac ttctaatgtt tcagagttat atcgtttgcc atgacatact tcacaaggaa
     8341 catagacatc aggcaaaaag tgcatttcga tcttaataat tccatccccg cgacaagctt
     8401 cacaacgacc gccttttacg ttgaaactaa aacgcccttt cttataaccc cgcatttttg
     8461 cctcgttcgt ttgagcaaat aacccacgga tatcatcaaa tacacttgta taagtcgctg
     8521 gattacttct cggcgtccgg ccgattgggc tttgatcgat atcgatgatc ttttcgatac
     8581 tttcgtagcc ggaaattgtc ttgaatttac ctggcttagc agaattctta tttaattttt
     8641 gcgctaacga tttctttaag atactattga ccaatgtact ctttccagaa ccagacacac
     8701 ctgtgactgc tacaaattct cctaatggaa attcaacact aatatttttc agattgtttt
     8761 ctgaagcacc agtgatcttg attgctttcc cattaccttt acggcgttct tttggtacag
     8821 ggattgattt tttccctgaa agatatttcc ctgtcaaaga attttcatca ttagctactt
     8881 cttcaggagt gcctgcagcc acgatttgtc cgccttgttc tccggcccca ggtccgacgt
     8941 caatcagata atctgctgcc cacatcgtat cttcatcatg ttcgactaca acgagggtgt
     9001 tgccaagatc acgcattttc tttaatgagc caatcagtcg atcgttgtcg cgttgatgca
     9061 atccgatcga tggttcatct aaaatataca aaactccaga aagattcgat ccaatttgtg
     9121 tagccaatct gattcgctgc gcttctcccc cagataatgt tccggaagcg cgactcaaag
     9181 ttagatagtc tagtcccaca ttttccaaga atgaaagtct gtcatttact tcttttaaaa
     9241 tcggtttggc aattactttc tcttgttcag ataacgttaa gtttgagaag aaatctactg
     9301 ctttttgaat agacaactca tttgtttgcc cgatattcgt tccattgatt tgaacagata
     9361 gagcttgggg attcaatcga taacctttac atgtctgaca agttaattct gtcatataaa
     9421 gacgcatttg ctcacgcgtg aaatcactgt tcgtatcatg ataacgacgc tcgatattct
     9481 tcaatacccc ttcgaaagtc gtttctacat cgcgaacgcc accaaaatca ttttcataat
     9541 ggaaatggaa aagatcatct gtcccattca agatgatatc ctgatgctct tccggtaatt
     9601 cttcgaatgg tgtatctaaa tcgataccga aactttcaca agcctgcgct aacatttgag
     9661 gataatactg agagctgatt ggattccatg gaacgatagc accttgacta agtgtcttcg
     9721 ttctatctgg aatcactaaa tcttgatcga cttctaattt gacacctaaa ccatcacagt
     9781 ctggacaagc tccaaaaggc gcattgaatg agaacagtct tggttctagt tcgccaacag
     9841 taaatccgca ataaggacag gcatagtgtt cgctaaacaa catttcttct tcaccgatca
     9901 cgtcaaccag agcatagccg tctgccaatc gcagagccgc ctctaaagaa tcaaatagac
     9961 gagaacgaat cccttctttc acaatgatcc ggtcgatgac gatcgcgata tcatgttttt
    10021 tgtttttctc cagctcaggc acttcactta aatcatagat ctcaccatcg actcgaacgc
    10081 ggacgtatcc ctctttttgg attcgttcga atattttttt atgttgtcct tttttcttta
    10141 ccacgatcgg tgccaacact tggatctttg tgcgctcagg caaagccatt acttgatctg
    10201 ccatttgatc tactgattga ctggtaatct cgatatgatc gttgggacaa atcggatgtc
    10261 ctacacgtgc aaacaacaag cgtaaatagt cattgatttc cgtcacagta cctactgtcg
    10321 accgaggatt tttacttgtt gttttctgat caatagaaat cgccggactc aatccgtcga
    10381 tgctatctac gtccggctta tccatttgtc ctaaaaactg acgagcataa gcagaaaggc
    10441 tctctacgta tctccgctgc ccttcagcgt acagcgtatc aaatgctagg gaactttttc
    10501 cagaaccgga caaacctgta acgaccacga atttatctcg tggaatcgtt acatctatat
    10561 ttttcaagtt atgggcacgt gcaccgtgaa tcgtaatttt atcgttagcc atgttgtcct
    10621 cctactttga agcttttaat tctaaaatca tatctcgcac attagcggct gtttcaaaat
    10681 ccaatgcttt cgccgcattt ttcatttctt tttctaattt catcaataac gtatcttttt
    10741 cttctttcgt catttcttca tacgagactt gtaccgcttc ttttgtatca tcttccgatt
    10801 ctttcgtaat agaaatcaaa tctcggattt ctttaatgat cgtttttgga acgatcccat
    10861 gttcttcatt gtacttctgc tgaatcgtac gacgtcttga cgtttcatcc atcgctagac
    10921 gcatagaatc tgttactttg tctgcgtaca tgattacttt accttcttca ttccgagcag
    10981 ctcgtccaat cgtttggact aaggaacgtt cactacgtaa aaagccttct ttatccgcat
    11041 ccaagatagc aacaagggaa acttcaggta cgtctaatcc ttcacgaagc aaattgattc
    11101 caactaacac atcaaattca cctaatcgaa gatctcgaat gatttctgtt cgttccagcg
    11161 ttttgatatc actatgcaaa tatttgactt tgatccctaa ttctttgaaa taatctgtga
    11221 ggtcttctgc catttttttc gtcaatgtcg ttacaaacac ccgctggtct ttttcgactc
    11281 gttcatttat ttcgcctact agatcatcga tttgtcccat gattggacga acttcgatca
    11341 ctgggtcaag cagccctgtc ggacggatga tttgttggat aacggtatct gtttgttcat
    11401 gttcatatgg tcctggcgtc gcagagacat aaatgatctg attgacatgt ttttcaaact
    11461 cttctaaccg aagtggccga ttgtctaaag cagatggcaa acggaaaccg taatctacta
    11521 gcatctgttt tctcgctcgg tcaccattat acattcctct gatttgaggc atggttacgt
    11581 gcgattcgtc cgccacgatc aaaaaatctt caggaaagaa atccaatagc gtataaggcg
    11641 gttcaccttc tttacgtccg tccatatgcc gagaataatt ttcaattccc gacgtgtagc
    11701 ccatttctaa catcatttca atatcgtaat tggttcgctg ttctaaacgt tgagcttcca
    11761 gaagtttgtt ttcatttcgc aagacagtta aacgctgttc taattccgct ttgatattcg
    11821 ctacggcatg ctccatatgt tcatcattcg tcacaaagtg agtcgccggg aagattgcta
    11881 cgtgttccgt ttctcctaaa acttcacctg tcagtgcatt gacttctcgg atacgttcga
    11941 cctcatctcc aaaaaactcc acacgtaagg cacgttcatc tcttgaagcc ggaaaaatct
    12001 ccacgacatc accgcgcact cgaaaacgac cgcgctgaaa atctatatca tttctttcga
    12061 attggatact gactaagtca cgaatcaact gattgcgatc tagttctgct ccctgtcgaa
    12121 tcgaaactac ttgtttttgg tactcaaaag gcgagcctaa tccaaaaata catgaaacgg
    12181 atgcaatgac gatcacatca tttctttcta ataatgaact agtagccgaa tgtcgtaatt
    12241 tgtcgatctc atcatttaca cttgaatctt tttcgatata cgtatcgctt gaaggcacat
    12301 aagcttcagg ctgataataa tcataataag aaacaaaata ttcaacagca ttgttaggga
    12361 aaaattcctt gaattccccg tacagctgac cagccaatgt tttgttatgg gcaataatca
    12421 gtgttggttt attcactttc tcaataagat tggaaatcgt atatgttttc cctgttccag
    12481 tcgcacctaa taagatttgt gcttttttcc cgccgactac gccatccact aattggttaa
    12541 tcgcttcagg ctgatcacca gccggttggt atttcgagac aagctcaaag tgtcgggagg
    12601 tatctctctc aatcattctt cgtcctcctt ttcattcatt ccttttcatt ttacgaccaa
    12661 taaaaagaaa aggaaagcaa aggcattcct tactaaaaaa ttataccaca ccgaacatac
    12721 tttcgccact tttttatctt attatacatg ttatgtttta taacataaaa tgttagaaac
    12781 tcgcattttt ttcatttttt cgagcttaca gtcttgtctg attcagcact tttcgcctat
    12841 aataataaaa tattggaaat ttaggaggtt gattatgaaa agaaagcatt tatttcactc
    12901 atttgttttc ttaatgacag gacttgtgac acttgcgttt ggtcatgttg cacaagctga
    12961 caacactaca acggcagagt caagcacaag cgagacaatg caaaaaatag agcccaaaaa
    13021 agacgtatac gtaattgcca gtgactctgc ttttgctcca tttgaatttc aaaacgcaaa
    13081 gggcgagtac gaaggcatcg atgtaaaatt gatggaaaac atcgccaaac tgcaaggatt
    13141 taacatccga atggactacc gtggtttctc tgctgctttg caagctttgg aatcaggaca
    13201 agcagacgga atgattgccg gaatgactgt aacagatgaa cgaaagaaaa gctatgattt
    13261 ttctgattct tactttgata gcgggatcca attagctgtc aaaaaaggag atacttcgat
    13321 caagtcttat gaagatttga aaggaaaaac agtcggagca aaagttggta ccgaaagtgc
    13381 tgaattttta agcgaccatg aatctgaata tggctattct atcaaatatt ttgatgctgc
    13441 tgatcaattg tacgacgggt taaaagttgg cgcaatcgat gcaatgatgg atgattatcc
    13501 ggtaatcggt tatgcgatca aacaaggaca agaattggaa acaccgatca aaaaagaatc
    13561 tggcggaaaa tatgcatttg ccgttaaaaa aggacaaaat cctgagcttc ttaatatgtt
    13621 caatgaagga ttgaaagaat taaaaagaac aggcgaatac gataagatta ttaaagaata
    13681 tgtagcggat ggttcagaaa cttccagtga gtcttccact gctgatgaat caacatttct
    13741 tggacttatc caaaacaact atcaagcatt gttgaaagga ctttggagaa caattctcct
    13801 aactttgatc tcctttgctt tggctatagt aatcggtgtg atttttggat tattcagtgt
    13861 agcaccaata cgcgctcttc gcacaattgc tagtatttat gtcgatatca tccgaggaat
    13921 tccaatgatg gttcttgcgt tctttatttt ctttgggttg cctggtatcg ttggatttac
    13981 gattcctgac ttccttgctg gtgttatcac cttgactctt aacgcaagtg cttatatcgc
    14041 agagattgtt cgaggcggga tcaacgccgt tcctgtcgga caaatggaag cttccagaag
    14101 tttaggtctt tcttataatc ggacaatgca aaaaatcatt ttgccgcaag cgatacgcat
    14161 catgatccca tcattcgtca atcagttcgt tatctcatta aaagacacaa cgatcatttc
    14221 cgcaatcggt gtagtcgaat tgctgcaaac tggtaagatc attgttgcac gtacaacaca
    14281 aagtacgtat gtttacttga tcattgcgat catgtacttg attttgatca cagcattgac
    14341 aaaattagca aaagttttag aaaagaaggt gaagtaagat ggcagaaaaa atcttagttg
    14401 agcatttagt caaaaaatac ggcgataaca cagtattaaa cgacatcaat gtatccatca
    14461 acgaaggaga tgtcgtctgt atcattggcc cttcaggttc aggaaaaagt acattcttgc
    14521 gttgcttgaa tcgtttagaa gaaccttctg acggtgaaat tattattgac ggcgcccact
    14581 tgatggataa aagcacagat atcaacttgg tgagacaaca tatcggaatg gtattccaac
    14641 actttaacct attccctcat ctttctattt tggaaaacat cattttagca ccgatggacc
    14701 tgaagaaaga atctagagaa gaagcagaga aaaaagcaat caaattactg cagacagttg
    14761 gtctagaaga taaaaaagat atgtatcctg aaatgctttc tggtggacaa aaacagcgtg
    14821 tggctattgc tcgtgctcta gcgatgaacc ctgacatcat gctttttgat gagcctactt
    14881 ctgcactcga tcctgaaatg gtcggtgatg tcttgaacgt catgaaaaag ttagcagaac
    14941 aaggtatgac gatggttatc gttacgcacg aaatggggtt cgctaaagaa gtggccaatc
    15001 gcgtcatgtt cattgacgac ggaaactttt tagaagatgg aacgcctcaa caaatctttg
    15061 aaaatccgca aaatgaacgg acaaaagatt tcttgaataa agtattaaat atttaataaa
    15121 aaccaaaaat gcacggtcgc catgaaggga ccgtgtattt ttatcttctt attttctcac
    15181 ctaatcgtat cagccgcatc gcttgttttc ctgcacaaac aagcaatcgc tctacctgtt
    15241 ccatcgcata agaaagtacc atcggttcat tgatgatatc aagtacatag tcgataccac
    15301 cctcacttaa ttgagcttga tttttcttct ccatattatg tagttgtggg acaactttct
    15361 gacaatcagc aattgtgtca agaacggatc aatcctttat tggagttgct cgaaagggtc
    15421 ttctcttatt acggacaggc tttgctcact gtacatagac aacaaatcat tatcctagtc
    15481 aatcggattt ccagagcctc attgctatca ttgcttgata aaatccagac aaagtttaat
    15541 aaaatgtatc agttacagct aaactttgga attgggtcgc tttgttatac agagcaagag
    15601 acaccgcaat ctttccttca tgccaaacaa gtttgcgaat ggatagcttt ccatcaatct
    15661 gtgaacgaga tccgcttttt tgaagattta gacctcggga tcgttttacc agcaatcccg
    15721 tcagatcaac gaacattata tgtaaaacgt attttgaaaa gcctgacaga agaagaagta
    15781 catttgttca agaagacttt ggcatgcttc agtaaaaata acggaagcat caaaaattgc
    15841 tcagaagaat tatttattca taaaaacacc ttgcaatatc gattgaacaa gttccattct
    15901 ctcactggtt atacccctag aaactatgac gattatcata ttctaaagct ggcttttttg
    15961 ttggtacaaa catgacaact acaaaaaaac caggcgaaca tatgattgtt cgtctggttt
    16021 ttaattatta atgacttagc gtttttacta gaaaaactac ttccgctttt tcccgccaaa
    16081 agcatcttta aacttatcga agaaaccgtc ttcttgctgt tcttcaactt tgatgccgcc
    16141 agcttcagcg aatgcacgta atgcttctct ttgttgttca tttagatttt tcggtgtgat
    16201 cagttttact ttgacatgtt ggtcgcctgt tgcaccacca cgtaacttcg gagcgccttt
    16261 tccacgtaaa cggaagttcg tacctgtctg tgttccagca gggatcttca atttcacatc
    16321 tccatggaca gttggtactt ggacttcatc ccccaaagct gcttgtacaa aacttaaagg
    16381 caattcatag taaatttcag aaccttcacg atcaaagata tcactttctt ctacacggaa
    16441 gaccacatac aaatcaccaa atggtccgcc gttttctcca gcttctcctt gaccagctaa
    16501 acgcatttgt tgtccttctt ctacaccagc tggtacattc actttaactg aatgtgcttt
    16561 cttctcatgt cctgagccat gacaggttgg acaaggttct ttgatttctt tccctgtccc
    16621 atgacaaaca tcacaagttt gacggctcat cactcgtcca agtggtgttt ggcgttctac
    16681 attaatcgta cctgcaccat gacatttatg acaagtagtt ggttgtgtgc ctggttttgc
    16741 accgttccca ccacaagtat gacagatttc ttcccgatta tacttgattt ctttttctac
    16801 accaaaaatc gcttcttcaa aagacaagtc gaccgtatat tgcaaatcag caccttgacg
    16861 aggcgcattt ggatcgactg accgaccgcc tcctccaaag aaagagtcga agatatcttc
    16921 aaaaccaccg aagccgccac cagagaagcc gccgaatcca ccaaatccgc caccagctcc
    16981 accagcaccg taatttggat ctgtgcctgc atgcccgtat tggtcatatg cagcgcgttt
    17041 ttgcgggtca cttaaaatct catatgcttc tgatacttct ttgaattttt cttccgcatc
    17101 aggttcttta ttgatgtcag gatggtattt tttcgaaagc ttacgataag ctttctttat
    17161 ttcatcttct gatgctcctt ttgagagccc taagacttca taataatcac gttttgttgc
    17221 cataggcttt cctcctattg gttctcatca ttttcacgtc gcttgttatc atatcatatt
    17281 ttgtttgaaa caaaaaccga tacttcaaac tatttttcaa aagaaaaagc caaagtagca
    17341 actttggcct tctctcgaaa ttcagtgaac tgattattta tcgtcgccat cgacttcttc
    17401 aaaatcagca tcaacgacat catctgctcc gccttgagct gcttctgggt tttcttgagc
    17461 ttgttgttgt gccgcttgtt cgtatagttt aacagtcaag ttttgaacga tttcgttcaa
    17521 tgcatcgcgt ttagttttca tttcttcgat gttgtttgct tcaacagcgg ctttcaattc
    17581 atcgcgagct gtttctgctt ttttcacttc ttcttcgtcc actttgcctt ctaattcttt
    17641 caatgttttg tccacagaga atagcaatgc atctacatca ttacgtaggt caacttcctc
    17701 tttacgagct ttatctgctt ctgcatttgc ttctgcatct tttaccatac gttcgatttc
    17761 ttcgtctgtt agacctgaag aagatttgat cgtgattttt tgttcttttt gtgtacctag
    17821 atctttcgca gatacattta caatcccgtt tttatcaata tcgaatgtta cttcgatttg
    17881 tggaatacca cgaggagctg ctggaatatc tgtcaattgg aatcttccta gagttttgtt
    17941 gtcagcagcc attgggcgtt caccttgtaa tacatggatg tctactgctg gttgattatc
    18001 tgccgcagtt gagaatactt gtgatttact tgttggaatc gttgtattgc ggtcaatcaa
    18061 tttagtgaac actccaccca ttgtttcgat acctaatgac aatggtgtaa cgtcaagtaa
    18121 aacaacatct ttcacatcac cagtgatcac gccaccttgg atagcagcac ccatagcaac
    18181 tacttcatca gggttaactg atttgtttgg ttcttttcct gtttctttac gtactgcttc
    18241 tacaactgca gggatacgag tagatccacc gactaaaata acttcgtcga tttctgattg
    18301 tgataaacct gcatctttta gcgcttgacg tactggtact tttgtacgtt ctactaagtc
    18361 agctgttaat tcatcaaatt ttgcacgtgt caatgtcatt tccaaatgca atggtccaga
    18421 ttctcctgct gtgataaatg gcaagctgat ttgtgtgctt gatacgccag ataaatcttt
    18481 tttcgctttt tcagcagcgt ctttcaagcg ttgtaaagcc attttgtctt gagacaagtc
    18541 aatgctgttt tcttttttga attctgctac catgtagtcg atgattttgt tatcaaagtc
    18601 gtccccacct agatggttgt cgccagctgt tgacaataca tcaaagacac cgtctcctag
    18661 ttcaaggata gatacgtcaa aagtaccgcc accaaggtcg aatactaaga ttttttcgtc
    18721 gcgatctgtt ttatctaaac cataggcaag agcagctgca gttggttcat tgacgatacg
    18781 ttctacttct agaccagcga tcttaccagc atcttttgtt gcttgacgtt gtgcatcatt
    18841 aaagtaagct ggcacagtga taactgcttt ttcgactttt tcacctaaat agtcttctgc
    18901 gaatcctttg atatattgaa ggatcattgc tgagatttct tgtggtgtat atgatttacc
    18961 ttctacatct actttgtaac ctgcttcacc gatatggcgt ttgattgatg aaatcgtatt
    19021 tgggtttgtc acagcttgac gttttgcaac ttcccctact tggatttctc catttttgaa
    19081 tgatacaaca gaaggtgttg tacggtttcc ttctgggtta gcgatgattt ttgcttcgtt
    19141 tccttccaat actgctactg cagagttagt cgtacctaag tcaataccga taattttact
    19201 cataattaac gtctccttct ttaattgaaa gtgtaagttt tatatccgca caattattgt
    19261 gcaacaatga ccatggttgg tcttaacacg cgatcatgta atttgtagcc ttcttgtagt
    19321 acttctacaa tcgtatcggc tggtgtatct tcagtcgctg gaacagtttg tactgcttga
    19381 tgaagattag gatcaaaggc ttctccttta gcagggattt tttcaattcc ttcttcttcc
    19441 agtgcgttac gcaaactttc caagaccatt tccacgcctt ttttcaaacc tgccccttga
    19501 tcatctgaca cttctgtggc taatgcacgt tccaggttgt caattgatgg aagtaatttt
    19561 ttggctaaat cttgtgaacg gtatttttgt aattgctcac gctcattttt tcctcgattt
    19621 gccatatttg cgatttcagc acgagcccgc aagtatttat cttccatttc ttctaactca
    19681 gcttttaatt tcgctgtttc gaattcttcc gcttcagctt ctgaaatacc cgaatcttct
    19741 gcagcttcga catcgatttc cggttctggc tgagcatctg tcatttcttt atctagttct
    19801 tcttgatttt ctttcacgat acagtcttcc tttcattatt cagtcagctg tttgattgct
    19861 cttactaaga aagagagaac gatcagctgc aaatagcttc gttattcaca ttacgagttt
    19921 gacaagtcaa gcgaacggta gtaatcagca agtttagctg ctagttctct tcgataaaca
    19981 tcgactagac cgaacatccg agaataaggc atactagtag gccctaacaa ggctattgta
    20041 cctcttccat gaccatctat ctcgtaactt gcttgaatca tactcatatt ctgcaataaa
    20101 tcattgccta attcagcacc aatcttgata tgaatattgc tatccatcgg agtgatcatt
    20161 tgtgtaagtc cgtctgagtc tttcataaaa gaaaacatcg atttgaactg atcaagatct
    20221 tgacggggct cataatccaa gagattcatt tgtccactga cataaacctt atcttcaaaa
    20281 acatgaccaa gaacggtgtc aaataactga gacatccctt ctgtcgtttg gaaatattta
    20341 tgaagaatca tcggaatctc cgtacgaagt ttatggtaca ccgtcatcag aggatctccg
    20401 actagacggt cgtttacaat ctgtaccatt ttttctagtt cctgacttcc catatattcg
    20461 ggaagagtga acacttggct ttctacattc cccatatctg ttacgacgat agcaataatc
    20521 tgtcgattat tcaagggtac gatacgaaag ccagtcagtc ggcggtcttt tatttcaggt
    20581 cccaatgaaa aagtcgtata gcttgtcagc tcagataata tctcagcaga ttgcttaata
    20641 atctcattga tttcatgaaa ttctctgcct agagactgac gaatcagcag caaatcatct
    20701 tctgctacgc gagcaggttt taacaaatga tccacgtaat aacgatagcc taaagcagat
    20761 ggaatccgcc cagaagaaga gtgagtcttc aacagcaatc cttcatcttc taatgctttc
    20821 atatcattgc gaatcgttgc tgagctggcc ttgactccct cagacatcaa tgttttggaa
    20881 ccaacgggca cgccactact cgtatagtgt tggatgatca gacgtaaaat gtcgttttgt
    20941 cgctttgtta acatcttcct cacctctcat tagcactcat atattctaag tgctaatcca
    21001 cttataaata tagcaagaag cccttctcct gtcaagagaa agactccatt ttttagcact
    21061 ctaaacacaa gagtgctaat tctaaataat tgatgtaaat ccagttatat caacgtttca
    21121 atagtccttt attgtatttt tgaacttttt ttatttaaat tcagataaaa aacaaatatt
    21181 ctttaaacta tttttcaaac aaaaagcgct caaacacatt gttccccaaa aaggtccctc
    21241 ttggtgtcaa ataaacacgg tcttcttcat taacaagtaa cccttcttgc tctaattccc
    21301 ttagcacatc accgtacacc gattcaattg ttttttgata gcgatcatag aaatgttttt
    21361 tagtaatccc tgtttttttt cttagtccta agaacatttc ttcttctatt tgattttttc
    21421 gtgtcaattt ttcttcttcc aataccgggc gttcatttgc tcgtaatggg cgtaaatagt
    21481 gttggattgg tcctttgttg cggtaacgaa tatctccaag ataaccgcta gcaccagctc
    21541 caaacccaaa atagtgggca ttgttccagt acatgaggtt atgttgagat tcatgtccgg
    21601 agagcccaaa gttacttatt tcatattggt gacgtccatg cttttccatt gcttcaatcg
    21661 tctcttcaaa cattctggtt tccgtttcct gatcaggcag ttcgagtctt ccttgtcgta
    21721 cccagttcat gaacattgtt ttgttttcga ggatcaatga gtacaaagaa tagtgaggca
    21781 gatccaaagc caaagctttt tccaaagtat ccagatatcc ttctagtgtt tgtcccggta
    21841 atgcataaat caaatcgatg cttacattgg taaaattttc tgcttctaaa aattgcatag
    21901 tttgatacac atcttctgcg gtgtgtttac gtccaatttt tttcaataag cgattatcaa
    21961 atgtctgcac tcccatggat aaacgattga cgccatagtt tttcattact tgaagttttt
    22021 cacgggtcaa atcacctgga ttcgcttcta cagtaaactc attaccattt tgaaaaggca
    22081 ggatctctct agcacctgat aacagtcgat caagttgttt agcagataaa gaagttggtg
    22141 tcccgccccc tacgtaaagt gtttctaaat tcgctgtcgg atgactttct agcattattt
    22201 tcatttcatt cagcagcatt tccacatact catctactgg ctgcccttct aaaaaaactt
    22261 tattaaaatc acagtaatag cagatatgct cgcaaaatgg gatatgaatg tacgcagaaa
    22321 ccttgttttc tgcgggattt attgtttcta tcattgaaat tctttctcct tacgtcgaaa
    22381 agtcgtgcct gttttcgacc ttcttaaaat cgcgttcaag caccaactca ttgaaataag
    22441 ccgcatattt agaatcaagg aaacctagct ctaaaaatgc ttgcttattg tcatcggagc
    22501 tacacggtgc ttttacagcc tctcgataaa cggtaatcgc aaagctgacc ttcggcatta
    22561 agtcaaaatc tgcaaaaata tgaaaagcta ttttcacaga ttcctcctta agtgctcaga
    22621 ccacaacgct ttgcttacaa cctctcatat acgcatacta aacgtatttg gcgaacaaat
    22681 ccactaaaaa atccaagaat cgacttcttg gatgattttt tctttcatta aactggttac
    22741 ctagttatat atctctaggg ttgttttcat gtctgagtgc ccgatatgat ttatttttcg
    22801 tttctataat tactttttgc cttccagttt cttttaatat tgtactcaag caagtgggaa
    22861 ttggttcttt tgtcatccat gtatgcaaaa tgttataatg ctggtaaaca aaaatgatta
    22921 cctgtcattt ttatttagtt cgtatttaat taagttgact atctgtatac tctgtctaaa
    22981 acttaagaat tgttgttttc gctgtcgcta cccaatttta atgaatgtct gtaggttaaa
    23041 actgttgtcc ttgttataga tagtaaagga gagcttgaaa atgaaaactg cgattacgtt
    23101 tctattagag gaatatgccg attgggaagg tgcttatatt actagcacac taaaccaaaa
    23161 tgagaaatgg caaaacaaaa ctgcttctat ccaatcagag gtcacttcca ttggaggatt
    23221 aaaaacaaaa atcgattact taatcgaaca aatacctgaa aaagttgacc tttttattat
    23281 gatcggtggc aattcatggg acataaaaaa tcatcattta tatcaaataa tcgataaatt
    23341 gttaaaaaca gacgtaccag tagctgctat ttgtggggca gttgattatt tagctcagag
    23401 cggattattg caaggttaca aacacaccgg aaatgcgcaa tttccttggt tagaatcgga
    23461 aaattatcag aataaagaag attttataga acaacaagct gtgaaagatc gtaatttgat
    23521 tactgcgaat ggaacagctc ctatagaatt cacagacttg attcttcaag cagtccattt
    23581 tgaaacagaa gaaataagag aaaaaacgat tcgtctatac aaacttggat tctatgatta
    23641 ctataaaaag tacggagatc ctttctccta atcattctct tcaattaaat actccttatc
    23701 aatagtgtga caagtaattt tactgatgat tatttgtcac actttttctg acatttatca
    23761 aagaagatac actctattta tattcataga caaggtttta cggattcaaa aattcaggat
    23821 tatgctatac tggtattaaa aaaataatga ggtattttat atgaaaaagt taggttttat
    23881 tttattgttg gtctctttat tccttgtagg atgtacgtct cctagtaaag aaaatagtga
    23941 tccatctgcg accacagaca aaagttcaat cagacaaacc agttcagctg aaaaatcaag
    24001 tactcagaaa tcagcttcta ctgaaacgaa tacatcttca acaagcagta aagtctcaga
    24061 gcccaatact tcttctacat ctagtagtac agttgagaca aatatttctt cttcaacaat
    24121 agacacaacc tcctcacagt cttctcagtc aatagatccg ttagcaggat attctgatct
    24181 acaaattgag tacgcacgtg tttggctagc tattagaggt aatactttta gagatacatc
    24241 gggtgatttc gaattacatg ttattcatta tcctgcagga acacctatcg ccccttatga
    24301 tgcagggagt gcagtctatc cgaaagatgt ggttatgctc actgggaaat acagttacca
    24361 gggagtttta gtgtattcaa gtaaccatga cgggacaatc actagttatc cagttccttc
    24421 acattggcaa atgcctgcag atcaaacatc ttatccagcg ttcattagag aaacaactca
    24481 agaaatcatt gataatgcat ctgtagtagc tattcctaca ggaaatccca atgacgtgaa
    24541 acagttaatc gatgtgacag ttatagataa ttagactttc taatatgtta tacaaaaaga
    24601 agctgacagc attttgtcag cttctttcac tttcttttct atttagattt attggtcttt
    24661 gatagactcc aaggcaggaa aaaatttttt aaataaacgt ttgcaaaaca gtcgcttttc
    24721 tatcttctac cgctacttct gcataggcac cattaatcaa tgtcagttgt ggcggtacat
    24781 gaccacaatc aatatcatac aagatcggta gttttaattc ctttgacaga tcttcgtata
    24841 catccttcat tttataatct aacaaatcct ctgccgcact tctaccgaac atgatccccg
    24901 agctgccatc aaaccagcct gccagtttca tctgaacaag tgatcttctt aaatcaactg
    24961 acgatagctc acagttttct agaaaccaca agatcggctt tccatcatta tactttcttt
    25021 taaaagattg gacatctcca taaggagtac cgattaaatg cctgatcgta tcaatacaac
    25081 cacctaataa tcgtcccttc atccttactg catctccgct gactgattgc caatttgttg
    25141 gttcagtgag atggaaaaca gaagatgatg aatgctcatg gggccacact ttttgatact
    25201 tttcagaaga ttgctgtaga atcgattctc cttctcttgt tttcagtaca ctttcccaca
    25261 ttgctgtcgt ttcatccaag tactctcctc ttaaatcaat aaggttagtt ccatgtgcag
    25321 tggctatccc tgtttttaat gtgacagcaa gtagcaacgt actaatatct gaataaccta
    25381 ctatccattt tggttgtaga gcatcaaaat cgacaaaatc gagaatctca atcaataatt
    25441 ctcctcccca agtcggaaag atcatttgga tattttcatc ttgcatcatt tgattgaatt
    25501 catctgctcg ttttcttgct ggacctgatt tttccttatc ttgcgtccaa agcgtctttc
    25561 cagtaactac ttggaaagat ttttcttcca ttctctttaa agctgattcg agtaacgaat
    25621 ggtgttcctc tgatacgcct gaggatggtg cagtaacccc aatcgttgca tttctttcta
    25681 ataatggata acttatcatg ttgcttcacc tccaagtatg cactatttta cttggttaat
    25741 tgtttttttc gtttgccggc atcaaaaata tcggcatctc aagtagctgg atgattttgt
    25801 ttaagtcaac cgtttggatg accatcgttt gatctggtct acctggtgca aaaacaagtt
    25861 tttcatttga taagagctct tcatcaataa taatcggaat ctgtttttca taaccaaacg
    25921 gagaaacagc gccctgcttt tgtcccgttt gttcttccat gcgttctgat gaaacaatag
    25981 aaagcctttt accgacgatc ttccctaatg ctttgaaatc cgtttgtttc gtagtaaaag
    26041 tcagatatac gtagttatta tcttttttat cttttaagaa taagcttttg gtctctgtac
    26101 ctgtaaatcc ttgttctttc tttattacca aagcatcttc atttgtataa atggctcgat
    26161 gatgatacaa ctcaaaatat atattttcgt gtaagaattt ctttgccaag tcaatcattt
    26221 ttatgtctct tttctatttt attatttgag acatcttatc atataaatat agcggttaca
    26281 acattacttg tgttttgttc gttttttata cataactatt gtttttctgg taaaataaat
    26341 caaaccactt aatggaggcg ttttagaatg gaaaaatttc agccgatcat caatcaaatc
    26401 aaagaaaaag aacatcaaca aaagatcaaa gacctttttg ctaagataac agaaacgtat
    26461 ccccagctag acacaactgt aaaatggaac caacctatgt ttactgacca tggtaccttt
    26521 attattgcat ttagttttgc taaaaatcat ttttctatcg caccggaaaa agcagcgatt
    26581 cgtgcccttg aaaaaaatat ccaagaagca ggctacgtat atacggataa cgtcatcaaa
    26641 gttccttgga aaagtgtaat caactgggaa ttgattgaac aattgatttc atttaatatt
    26701 gaagataaaa aaggtcatga taaattttgg cgataaagct ttatacgaat aaacctttta
    26761 ctggcgagga aactattcat caccttatac aggttttgtt caatcctatc ctttttatca
    26821 tccctggtta aacacttaat tgacaaagta tctgctattt ttataaggag tctttcttgt
    26881 gctgaaaaaa atcactgatt gaatggcttt gaattttcta cttagtaaaa ttattttttc
    26941 agcaattttc ctgcaaaact tttgaataag gaaaaaatac gagaaaatat cagtgatctt
    27001 tcataatact gcccattatt ttcaggtata tttaaatata atatcacttt aggagagaac
    27061 gaatttcttt agagaaataa aagttagaat tttctgactt gatttttaca atgaccttaa
    27121 ttaaaatcgt tctttctaca tttcgtgatt aagcaaatat caactaagtc agtagaacca
    27181 ttcacatagg agggtgaaca ttgaaagatt tttactcagt aaatgaatta gccgaacaat
    27241 taggtgttac tacacgttct atcagaaatt atcttcatga aggaaaacta aaaggaacaa
    27301 aggttggcgg gcaatggaaa ttttctgaac gtaatctttt tgagttccta tacggagatc
    27361 aagcagagga agcagcaaaa gaaatgcagc gattcatgct aaatgcacca atcacgatgc
    27421 gtttcaacct tcaatatcgt gattttacag caatcaatca attccgagaa caattagtcc
    27481 agtaccataa cgatgtttac gcaaataaaa aagaccgtct tttacaatac gatctttata
    27541 aagacaatca tgcggagata ctaatcggtg gtaacttcaa ttatgtcgta aactttagtc
    27601 aatggatcaa tgaaaaatta ttgatccaga cagatatttc ccttgtatct taaacaatta
    27661 aaaagcgcta gaaattccag agatgttgga aattctagcg ctattttttt ataagtactt
    27721 actgtttggt tcaaacaaat atttttttaa taaatgaaat tttaccatct ttatcctcaa
    27781 ataaagaccg tgaccatgct tcctactacg atcagcaata atccgataat cgttaatttt
    27841 ttttcttttg gtgtcttatt ttcatgcagg atgtacatac cgcctaatgt agagataact
    27901 acgtttagct gtgtaatgat atatgcagta gcaaccccat tttcatttgc tgaaaaaata
    27961 taagccaatg ctgacacact aaagatggct ccaacgatcg ttgctttcca actcttgtct
    28021 tcagaaaatg cggttggttt acggaaaatc acataaatca ctgcccctaa aaagacaccg
    28081 atcatttgcg gaaagaaaat ggaaagtccg cttgcatcaa ctagtttagg caatgcactg
    28141 tatacccaat aaccaatact tgttgatgct aatagactaa ttccttttgt gataccgcct
    28201 ttttttccag gatcatcact gattgccgtt aaagcagaac caaatacaag aagaatgatt
    28261 gctgctgctc caatgatttt ccccatactt ccagaccatt ctccaaaagc gaagacacca
    28321 atcaacgagg ttccgactaa ctgtaatgca gtcgaaattg gcatcgtttt agaaacacca
    28381 atcaagttga aagatgtata ctgtcctgtt tgtccaataa cccaaaatgc accagaaagt
    28441 aaactaatca aaaatgtagt cactgaaata ccagctggag aagcgaataa ttgaacgagt
    28501 aagccgacaa gcaccgctcc aataccagtt cctaatatct catttgttgg tctgccacca
    28561 atctttttca aaatcagtgg ctggatcccc cagccaactg ccgggatcaa tgcaatcaat
    28621 aaacccattt ttattcaccc ttatcctttt ccaccttgga aagaaggata taaagtcatc
    28681 ccaccatctg caaatagtgt aatacctgta acataactgg attcgtctga agccaaccat
    28741 gcagctgtcg ccgctatttc ttttggttca cctacgcgtc ctagtgggat catactttcc
    28801 aagagttctt tttgttcagg atcatcaaat tttgccgcat taataggtgt acggatagca
    28861 ccagggccta tactattgat tctgattccc ttcggtgcat actccattgc taccgtttcg
    28921 gtaaataatt ttaccccgcc ttttgaagca gcgtaatgag caaacgttgg ccatgggatc
    28981 tgttcatgaa cagaagacat attgatgata tttccttttt tattattctc tgtaaagtaa
    29041 tttaaagccg ctttcgttcc gataaaaacg ccagtcaaat tgacttttaa cactctttcc
    29101 caatcttcaa ggctaagttc atgggttgga tgctgatttt ccatcccagc attattaacc
    29161 caaacgtcca gtgtcccaaa attttctaaa gccgtatcaa gtaaacgctg tattccttct
    29221 tcagaactga catctgcttg tacagagact gcttttccgc ctgcctcttc gattgctttg
    29281 actgcttttt ctgctccttc tttatccgag ttatagttga caactacatt cattttttct
    29341 ttcccgaatc gttgagcaat cgctgttcca atcccctttg agccaccagt tactactgcg
    29401 actttgtttt ctaattcctt gtacatagta cccactcctt tttcatacct aaacctgtta
    29461 ttacggataa cttttatttc cgccttaaag tgagtgtaca ccaagatata tagtctaaag
    29521 caaatgatac gctctagcaa tcgttttcat gaattgctag tgtcctttta tttctataaa
    29581 gaaagaggtt gtgacagaag tggtcagctt caagaaattt cggcttattt ccgaagaagc
    29641 tacttctgaa aaaccattta tttggaaaaa aaggctgtga caagactttt gtcacagccc
    29701 ctttcctggg cttatttatc acccatttta ttgtaattgc tagttataca taaacaagag
    29761 attttatgca taatgtttta ttgctgagaa aaatattcag ctgttgcttg ttcatcctcc
    29821 ttgagttgtt caatcaattc ctctacacta gaaaatttca cttgatctct taaaaattga
    29881 ttccagcgta ccgcgacatg ttcaccatag atatcttgat taaagtccaa aatatacaac
    29941 tctacagtca gctcccgtcc ttcaccgaat gtatcattat gtccaattga acccatggct
    30001 ggataccatg tttccccaat ttttatttcc gacacataaa caccttcttt aggcaaatga
    30061 accgtgctct ttactttgac atttgctgta gggaatccta gtagtctgcc tcgtgcatcg
    30121 ccatggacaa ctaccccttc tacctcatat gtgcaaccta atagttttgc tgcttctttt
    30181 acttgtccgc tgtctagtaa tccacgaata cgggtagagc tgattttttc accttgttct
    30241 tcttctttag aaactgtgac gattttgaat cttcctttgg catattcagg aaaatgagcg
    30301 acatctgcaa tgtcttttgg tccatacgta taatcaaaac cggaaacagc atattttgca
    30361 tgtaacccta cgatgtattg atcaacaaat tcctgcggtg ctaaatgagc aaaagaagaa
    30421 gtaaaatcaa cttcatataa ataatctata cccaaagcgg ccattttttc ttctttttgc
    30481 ttaaggctag tcaaatattt cacgctgcta ggatcgatct ttttaaagac aatagatgga
    30541 tgctgattga aagtcatcaa tgctaatttc aatccttctt tttgtgcaat ttccatacct
    30601 gtctttatga ctttctggtg tccgatatgc acgccgtcga aaaatcccag cactaaaacg
    30661 acatcgtctt ctggaatttg ttctgattgg taaggatgtc tgatcttgat gatattcatt
    30721 cgttattcct catttctcaa tactttacta ggttttaatt tgtttttttc tttcgggttt
    30781 ggctgataaa tactgacaac ttttccttta taaaacaaag caatttcttc tgacggcatt
    30841 tctgggagcg caaatacagt ataatcaagt ctcataccgt tttttacttt ctgccatact
    30901 tcatcagtaa tatctactcg tttgaaccgt tccactcctt tttctattgg cagcaaacaa
    30961 tcatcgattg tcccattttt cacagcttga gctacttctt ctaatgtcag agcatccttc
    31021 tgggacatac cggcacttgc tgttcgggtc agatcagaca tgtgcgcagg gtaaccaagt
    31081 ttcttgcctg tatctacagc taatgtgcgg acataggttc ctttcccgca ttctacttcg
    31141 aagcgccaag aaatggttcc tgtcacttcg tctcttgtca attcacttgt ccggataaaa
    31201 cggtaaatct gagcctttct aacaggacgc tccactgttt cattattgcg ggcatattca
    31261 tataaccgct taccgttgac ttttaccgct gagtacattg gtggtatctg ggtgatctca
    31321 ccaataaatg aagccatcac ttcatctatt tttttttcag ataaagacat atctactggt
    31381 tttgtttcta cccgttctcc ggatcgatct tccgtcgttg tactgaaacc tagagttatc
    31441 tcgcctacat agattttccc agaatctgtc aaatattcga taacttttgt ggcttttcca
    31501 atacaaatgg gcaacacacc gtctacgtct gggtcaagcg tacccccatg tccgattttt
    31561 ttcgtatgta agatttttct taatttgaat acgcaatcat gacttgtcat tccgcgttct
    31621 ttccataaag gtaataaccc gtccatgtct tttctccatt tcatttttga tttaactgaa
    31681 ttattataac acattgcatc aattactgac gaatttgaca tcataatgaa cggtttttat
    31741 ttttcggcaa taaaaacgta acaaaattca tgctcacgta aatagaaatc atgttatgct
    31801 tttttaaagg agggaataga atggaagatt ttttctttgc accatttgat tggatttatg
    31861 ggtggcttac aggtaaatag tttggttttc acttcccaaa aacgaaaaaa aagactggcc
    31921 attcttccag tcttttttcc gtttttttta tttatttttt cagtttctta atcaatgtaa
    31981 aaaattctat tttgcgggat cgattttatc attttattgg tcaagatttt tccatttcca
    32041 atccaatact tctggcagat caataccatt ttcacgaata tagttttgat gttcttgtaa
    32101 tttctgatcc atttttttcg caaaatcttc tgcttgactt cctttgattt ttaaagctgc
    32161 gtcttttgcc aaatgataac gatcaagttc atttactaca cgcatgtcaa atggtgtcgt
    32221 gatatctcca ttttctttgt agccatgaat cattaaatga tggttatgac gatcaaagaa
    32281 aatcgtgcgg accaatgttt cataaccgtg gaaagcaaat aagatcggtt tgtcttttgt
    32341 aaaatattga tcaaattctt catcgctcaa cccacgcgga tcttgacttg gatgacgtaa
    32401 tttcaataaa tctacgacat tgatgaaccg aatttttagt tttgggaatt cttccagcag
    32461 caaagttaca gctgctaatg cttctaagtt agattccgtt cctgcagcag caatgaccaa
    32521 ttcaggttcc tcctcttttg ctgtcgaagc ccaatcaatg attttcaagc cttcattcac
    32581 taagacggct gcttcttctg ctgagtaaaa ttgagcacgc ggatgtttgg aagagatgat
    32641 caaattgatt ttttctgacg agcggaatgc tttatccatg actgcgagca atgtatttgc
    32701 atccgcaggc agatattcac ggatgaactc cgccttcttt tctgccaaat gtgtcaatat
    32761 tcctggatct tggtggctat atccattgtg atcttgctgg aagactgttg agcttgcaat
    32821 gagatttagc gaaggataat catttcgcca agaaaggtca tgtgatttcc gcatccattt
    32881 gaagtgctga gtcaacatag agtcaaccac tcgcaagaat gattcgtaac ttgcaaaaaa
    32941 ccatgccgtc cagtcagaac gtacccttct aagaaccctt catcttggtg ttccgataat
    33001 tgactgtcga tgacgcgacc agatggcgaa agccattcat cattttctgg ttcgattttt
    33061 tccatccatt ggcgatttgt cgttttgaaa acttgattca atcggtttga ttttgtttca
    33121 tctggtccaa atatacggaa attttctgga tttttctcaa tgatctcgcg aacgaattta
    33181 ccaagttcgg tcatatcttc tgctttaacg gagcctggtt tttcaaattg caaagtatat
    33241 tttttccaat ctggcataat aagcggtctt ggatcgattc caccattggt gataggattt
    33301 tttgccattc tttggtcacc agtaggcgcg atttctctga tttcttctaa aatacgtcct
    33361 tgtgcatcaa ataatttttc tggttcatag gatttcagcc aacggagtaa agcatctgca
    33421 tgatccatat gttcttgatc tacaggaatc ggtacttggt gtgctcggaa ggttccttca
    33481 attggttccc cgtcccattc ttttggaccg gtccatcctt ttggtgtgcg tacgatcaat
    33541 actggccatt ttggcatcac gacatctgtt gctgtcttca ggcgagcttc tttttggatg
    33601 gatttaattt tctcgattgc ttgatccatt ttttcagcca taacaggatt taatttttct
    33661 gaatcatttc cttcaataaa gaaaggttcc cagccaagtc cgttaaagta atttgctaat
    33721 tctccatctg atttacgtgc caagatcgtt gggttggcta tttttgcacc atttaaatga
    33781 aggatcggta aaacagctcc atctatcact ggattgataa agacatttga gaaccagctt
    33841 ccagctaaag gaccggtttc tgcttcacca tcaccaatca cgacagcaga gattacttca
    33901 ggattgtcta atacagctcc gactgcatgt gaaagagagt atccaagctc tccgccttca
    33961 tggatagaac ctggtgtttc tggtgctgca tgagaagcaa tgcctccagg aaatgaaaat
    34021 cgtttgaata atttttgcat tcctgtctca tcttccgtta cttctggata gatctctgtg
    34081 taacttccat ctaaataagc attcgatacc atgacttgtc cgccgtgtcc tggcccttca
    34141 atataaaaca tgttcaaatc atatttattg atgactcggt tcaaatggac ataaataaaa
    34201 ttttggccag gaatcgttcc ccaatgaccg attggatgtt ttttgacatc ttcgggtttc
    34261 agtgtacgtc tcagtaaggg gttatcttta agataaagtt gcccaacaga aagataatta
    34321 gcagcacgcc accaagccgt cattttatca aagtattctt tactagaata atccatacat
    34381 aacactcctt ttcattatta ctcttattct agcgcagata ctcccaattg aaacctaata
    34441 agcacttctg ttcatttgtt tggattttat atctagccaa atgaacaggt ataaaaaacc
    34501 acgaaatttt tcctttcgct gacgtttttt acattgatcc aaaaaacttg tcgttatcac
    34561 aatggctgtt ccgcagttca tttcgctcct catcatgcat aatttgctga atgacgctgg
    34621 gccagttaac acattgctgg aaaactgggg ctggatcgag caattccttt cctgattgat
    34681 ccgttttatg taaaagtctc tgttatcttt gtcaatatgt gaattggtat cccagctact
    34741 atgctaattt ctacagggat tatccaaaat ttggatcgtg accaaatcga agcggcgtaa
    34801 tcggaaatat caataacttc aacgtgattt ttcttttaac tgtcaacgga ccgacaaact
    34861 caaactttta tggtgcaggt tccactgatc ttctagttac ttggctatac ctgactgtca
    34921 ctaaaataga ttacaatcta gcttccgtta tcggtatctt gatctttatc tatatgcaaa
    34981 aatttatata ctactagaaa aaagaaagtc gaatttttta cttttctttt tctctttttt
    35041 ggttagctga cacgccgcaa gactaaagtc atggaactct taggtaatac gtcttaatga
    35101 aaacaaaaaa atcccgcaac ccctgatttc acaggatttg cgggagtttt tgattagtct
    35161 ttgttcaagt cgcgaagcaa ttcatcgata tggttgccat agacaactga ttcatcaagt
    35221 tcaaagaaca attcaggtgt cttataaata cttagattgt gccctaactc tcgacgaatc
    35281 aatcctgatg ctttattcaa tccatcttgt gctgttttct tatctgatgc taagtcagat
    35341 aaaatgctgt aatagatcgt tgcttgctgt aagtcccccg taactttcac atctgtgatc
    35401 gttacgttct ccacacgagg gtcacggacc tttttgcgca aaatatcatt gacttctttt
    35461 aagatttctt gaccgactcg gcggtcacgg tagttagcca taatgattgg cctcctttta
    35521 tcagttttta gtcatttttg acttcttcca tgataaatcc ttcaattacg tcatctactt
    35581 tgatgtcatt gaatttttca atcattgcac cacattcata acccattttg acttctttca
    35641 cgtcatcttt gaatcgtttc agacttgcaa gttggccttc atagattacg attccgtcac
    35701 ggattacacg gacaccgcta tctctacgaa tatatccttc tgttacatag gcacctgcaa
    35761 tcgtaccaac tttagaaact ttgaaggttt cacgaacgat catttgaccg gtgatttttt
    35821 cttcaaattc agggtctagc atccctttca tcgcagtttc gatttcttcg atggctttat
    35881 agatgatacg gtgaagacga atatcgactt cttcagtatc agcttgcact tttgcctgcg
    35941 gtgtaggacg aacgttgaaa ccgatgataa tagcgttgct ggctgctgct aaggttacat
    36001 cactttcatt gattgctccg acagctgaat ggacgatttt tacacggaca ccttccacat
    36061 caatcttctt caatgatgca gccagtgctt ctgctgaacc ttgtacatct gctttgatga
    36121 ttacgttaac ttctttcaat tcgccttctt tcaggctttc aaataagtta tccaaagtca
    36181 cacggcttgt ggcagcacgg ttttctaata atgcacgttt cgcgcgttct tcacccgctg
    36241 cacgtgctgt cttttcgtct tcgaagacta cgaaacggtc acctgcttga ggtacatcat
    36301 tcaagccagt gatttctact ggcgttgcag gtcctgcttc tttatcgcga cggccaagat
    36361 cgtttgtcat tacacggaca cgtccgtaag tattaccgac aacgattggg tcaccaacat
    36421 gaagtgttcc ttcttggaca agtaaggttg acacaggacc tttaccttta tcaagacgtg
    36481 cttcgatcac tgttccgatt gcgcgttgtg ttggatctgc ttttaaatct tctacttctg
    36541 cgactaacag gatcatttcc agcaattctt cgatgttttg gccgaatttc gctgagatct
    36601 caacaaagat cgtttctcca ccccatgctt caggaattaa ctcatactca cttaattctt
    36661 gcataacatg ttgagggttt gcacctggtt tatcaatttt atttacagcg acgatgattg
    36721 gaacgcctgc agctttggca tggttgattg cttcaactgt ttgtggcatg acgccatcat
    36781 ctgcagcaac aactaagatc gtgatatctg tgatacttgc tccacgtgca cgcatacttg
    36841 taaaggccgc atgtcctggt gtatccaaga aagtgattgg tttaccatca atatcgatct
    36901 ggtaggcacc gatatgctgt gtgattccgc cggcttcgcc gcttgttaca cgtgaatggc
    36961 gtaatgtatc caataaagtt gttttcccat ggtctacgtg tcccataatc gttacgactg
    37021 gcggacgtga gactaattta tctggatcga cttcttctgc ctcgaagaat ttatcgatat
    37081 cagcaatgtc aacttggact ttttcttgtg gttccatgcc atagtccgtc gctaacagtt
    37141 caatcgtatc tttatccagt gcttggtttt gattgaccat gacaccaagc ataaataatt
    37201 ttttaatgat ttctgctggc tcacgatgaa tttttttcgc aatatctgct acgttcatac
    37261 cttcagtata ctctaataca tctggcaatt cacggaattt gcgtggtggt acagctggtt
    37321 tagttgattg ttgctgtttg ccttttttac cttttttatt ataacgatta cggttattat
    37381 tattaaattt gccgcgattg ttattgtttg gtttgttgtt attgttagta cggttttgat
    37441 tgccgccttg gctcgttcct tgacgatttt ggctgctggt atttcccgta ttattttggt
    37501 ttgttgttgg tttttttcct tgattcactt gaccgctccc ttgaccgcga tcttgataac
    37561 tgcggttatt tttatttttt tgttgattgt tcgttgtttc ttttttacgt tgatcgttcg
    37621 gctgttgatt ggctggtttt ctgcttgctt gttgtgcagc ttgttgtttc gtgcttgggt
    37681 ttttgaacgc ttgttgcaat ttcttctcat cattgctagt aatcgcaccc atatggtttt
    37741 tcacatcgat gccaagttgt tgtgcttttt ccacgacgtc tttactagat tttttgagtt
    37801 cttttgctaa ttcatagatt cttttgttgc ccatgcaatc accttcctaa ccttcaatta
    37861 gctccttggt cttcttcgca aatccggcat ccattattcc gaataccttg cgaggttttc
    37921 cgatcatctg cgtgatttct gcttcagaaa atagctcaaa gcaaggaact tcataatatg
    37981 aactcttatc ttttatcttt tttcttgtat tctcgcttgc atcggttgcc acaaacacca
    38041 attttgcttt ttgtttgcgg atttcagcaa tggtcagttc ttcacccgtg attagttttc
    38101 ccgcgcgcat cgctagaccg atgagattca tggctttttg ccgattaact gtattcattt
    38161 tccaaataac tctttacgtg ctttttggtg agtgacatag tcaagaagtt cttgataaaa
    38221 ctcatctgtt aatgttgttt cgagtactcg atcgagaatt tttttatccc aagcttgttg
    38281 tacttcttcc ggctcaagtg agacatacgc tcctcgtcca ggcatttttc cagttggatc
    38341 gatcgatact tccccttctt ttgaacgggt gattcggacc atctcttttt taggtttcat
    38401 ttcacctgaa accacggatt tgcgtaaagg aattttcctt tgtttcatct ctttgcctcc
    38461 ttactaaagt taagcttctg gtttttcttc gaccgtttca ttgttgaatg caattgtttc
    38521 atattcatcg tctgttaaat ctgactgaac gattgcttca tcatgcagtt cttctgtttc
    38581 tttttgttgt tcttgatttt cataaaattc cgtcatgtca gattctgatt tgatatcgat
    38641 tttatggtta gtcaatttag cagctaaacg tgcgttttgt ccgcgtttac cgattgctag
    38701 cgataattgg tagtctggaa cgacaactgt gcaggccttt ggatttgtct catcgaagat
    38761 cacatccatg acttgtgcag gattcaatgc atttgcaatg aatacagctg gatcttcatt
    38821 ccattcgacg atatccatgt tttcgccttt taattcattg acgattgctt gaactcgttg
    38881 tccctttggc ccgacacatg taccgactgc atcgatattt ggatcatttg agcgaactgc
    38941 cacttttgaa cgatcgccag cttcacgggc gatgctgaca atttcaacga ttccatcata
    39001 gacttctggt acttcttgct caaataagcg gcgcaatagg tctggatggc tgcggctaac
    39061 aaatacttgc ggacctttag acgtattttc tactcgggaa acataaactt tgattcgatc
    39121 atgtggttga taaaattcat ttggcatttg atcttgttta gaaagaactg cctcaatttt
    39181 accaagattg acataaatat aacgtttatc ctggcgttcg acgattcctt gcatgatgtc
    39241 tttttcataa gcactgaatt cgttataaat aatcgttctt tctgcttcac gtacacgctg
    39301 taaaataact tgtttagccg tttgcgcagc gatccgccca aaatcttttg gtgttacttc
    39361 aaaacggatc gtatcaccga tctcatatgc tggattgatt aaaagtgcat ctttcaatga
    39421 gacttccaac tgtgaatcca tcacttcttc cgttacttct tttaccgcat agacatggat
    39481 ctttcctttt ttctgatcaa attccacttc gacgttttgt gcttggccat agtgacgttt
    39541 gtatgcagaa accaatgctg cttctaaagc atcgatcacg atttcttttg agatcccttt
    39601 ttcagcttct aaagcgtcta acgcatttaa catttcttta ctcatttttt ctgattcctc
    39661 tccgtgatta aaattggata gctaagcgag cttttgcaat attttttcgg tcaaaagtca
    39721 attctttttc tcgtgttttt atgcgtattt tcaatgtaag ctgttcagca tcaaatgatt
    39781 gaagaaatcc ttcatattgt ttttcgccat ctactggttg gtataaggag acatggacat
    39841 aatcaccaag tgccttttca tagtcgcttt cttttttcaa tggccgctct gctcccgggg
    39901 aggatacctc caggaaataa gcttgaggaa tcggatctgg atctgctgca tcaagttttt
    39961 cactcagttt ctcactgaca aaggcgcatt cttcgatatc gataccgcct tctttgtcaa
    40021 taaatactcg taagaaccag ctttttcctt cttttacaaa ttcgacttcg acaagttcaa
    40081 aattttgttc atctaaaatc ggtgtcacca tttctgtgac tgtttcaacg acgctactca
    40141 aaagtttcgc ctccttaaaa aattaagtgc gtaattccat taaaaagagt gagcgaaaaa
    40201 tccgctcact cacagttagt atcattacct ataagaacta taccatactc tgcttaaaat
    40261 tacaagcaga caggaaaaca gatgcttata gcatatcgaa taacgataat tgattttcat
    40321 ctggtagatc tttcaatacg ccattgtcgt tcatatattc gatcaatgtt tttgaaactt
    40381 taccgcgggt ggcaagatct tctttggata aaaatggacc gtcttttctt gcttcaacga
    40441 tttgttttgc cacgttggtt cccaaacttg ggacagctct aaatggtgcg atcaacgtat
    40501 caccttcaat aacaaagtta acggcatccg atttatacaa atcaatcatt ccaaatttga
    40561 atcctcgttc cagcatttca ttggctaact ccagcactgt cagttgattc ttttctttta
    40621 cggaagcatc taatcctttg tccgtgattt ctttcattgc ttgtttcaca gcatcttttc
    40681 ctttgcacat ggagactaga tcaaagtcgt ctgcacgtac agaaaagtat gcacagtaat
    40741 acaaaatagg gaaataaacc ttgaaataag cgacacgaag agccatcaat acgtaagctg
    40801 cagcatgggc tttcggaaac atatatttga tttttgaaca agaatcgata taccagtcgg
    40861 gcacattatt ttctttcatc gccgatagat aggtttctcg caattcatca gggatcttgt
    40921 tccattgtcc tttacgaaca gtttccatga ttttaaatgc catcccgcta tctaatccag
    40981 catggatcaa ataaaccata atatcatcac gacagccgat tacttccgcc agtgtcgcat
    41041 ctcctcgtcg aatcaattct tccgcatttc ctaaccatac gtctgtacca tgagatagtc
    41101 cggaaatttg cagtagttct gcaaaagttg taggatgcgt ttcttctagc atccctcgaa
    41161 caaaacgagt gccgaattct ggaataccta atgtccctgt tttggaataa atttgttcct
    41221 gacttactcc aagtacttca ggaccggcaa atatccgcat cacttccggg tcatccgtag
    41281 ggatcgtttg tggatcgatc cctgataaat cttgaagcat ccgaataaca gttgggtcat
    41341 catgccctag aatatctaat ttcaatacat tatcgtgaat cgagtgaaaa tcaaaatgag
    41401 tcgttttcca ttccgaattt tgatcgtctg ctggatattg gatcggcgta aaatcataga
    41461 catccatata atcgggaata acgatgatcc cccctggatg ctggccggtt gtccgtttga
    41521 ctccagtagc gccttttgct aatctgtcga cttctgcact tcgaaactgc agattattgt
    41581 ccctttcgta tccttttaca tagccatatg ctgttttgtc ggcgactgta ccaatcgttc
    41641 cggcacggta aacatagtct tcgccaaaca atactttcgt atagttatgg gcttctgctt
    41701 gataatcacc tgagaagttc aaatcaatat cgggcacttt gtctccatgg aatcctaaaa
    41761 atgtctcaaa tggaatatca tgaccgtctt tgtttaagcg tgcaccacat tttggacatt
    41821 gtttttctgg catgtcaaat ccagaaccat acgtaccatc ttcaaaaaac tcggaatatt
    41881 ggcactctgg acaataataa tgaggggcta acggattaac ttcagtgatt cctgtcatcg
    41941 tcgcaacaaa gctagagcca acagagccac gtgaacctac tagatagcca tcttcattac
    42001 ttttatgcac tagtttttgg gcgatcagat aaataaccga gaagccatta ccattaatag
    42061 aattcaactc tttttttaat cgtttttgaa tgatctcagg taacggatct ccgtacattt
    42121 gttttgcttt tgtgtaactc aattctgata tttcatcttc tgaacctgga atcttcggtg
    42181 tataaagttc atctttgact ggaatcactt cttcgcagat atctgcgatt ttattcgtat
    42241 tttctactac gatctctttc gctgtttctt cccctaaaaa gtgaaatgca gttagcatct
    42301 catcggttgt tcggaaatgg acatccggca aactatgacg attcaacgga ttcgctccgc
    42361 ccatagaatt gatcaaaatt tttcggtaaa tggcatcttc ttcgttcaga taatgtacat
    42421 tacctgttgc aacaacgatt ttatccaaac tttttccgat ttctaccaaa ttttggataa
    42481 tttcttccaa atcatgttca ttttttacca attcttgctc gatcaaaggc gcatagaccg
    42541 cttttggcat aacttcaata taatcgtaga attttgctcg gtttcttgcc tcttctaccc
    42601 ctttttgcat catggcttcg aatatttctc ccttatcaca agctgagccg atcaatagat
    42661 tttcacgcat ctttttcaat tgggagcgtg gtattcgtgg gacgcgttcg aagtattcga
    42721 cattcgacat tgaaatcagt ttgaacaaat ctttcagtcc tgcctgattt tttgctaaaa
    42781 tcgttacatg gaaaggtcga gcccttttgt aagaatctcc ttctccgata tgctcattta
    42841 gctgatcatg ataaagcatg ttatgattgt ccattgcctc tttcacaaag atccatgcta
    42901 agtgaccagt tgcttcagca tcatagattg ctcggtgatg ctgttccaag ctgacaccaa
    42961 attttttaga taacacacct aatccgaaac gtttgaattg aggatacaga tatctagcta
    43021 attccaacgt atcaatgact ggattggccg cttcaggaat accatacctt gcgtagctag
    43081 tattcaagaa ccccatatca aaagccgcgt tgtgggctac caaaattgta tcttttgaaa
    43141 attcaaggaa catccgcaat acttcttctt ccgactttga tcctcgaacc attccatccg
    43201 tgataccagt cagatctacc gttgttcgtg acaaaggatg tcctggatcg ataaattcat
    43261 caaagctttc gatcacattt cctttataca ttttgactgc ggctagctcg atgatcgtgt
    43321 catatactgc agacaatcct gtcgtttcca cgtcaaatac gacatatgtg gcttcactca
    43381 atgcttcatg tgcatcatta taagcaattg ggacaccatc atctacgaca ttcgcttcca
    43441 cgccgtataa gattttcaca cctgcttttt ttccagcact atgtgcttcc ggaaaggctt
    43501 gcgcaccacc gtggtctgta atggcgatag ctcggtgtcc ccatttccct gcttgtgcca
    43561 caagatcaga gatgctgttt gttgcatcca tcgtactcat attgctatga acatgaagct
    43621 ctactcgttt ttccccttca ggagcataat ctttgcgagg tgtatgtttg acttctatga
    43681 tatcttgcgc attcatgacc aaatcacgga caaacgtatc ttcttgaata cttcctcgta
    43741 cctttaacca gctaccgaca ctgatcgcat caaatacttg ttcatctttt tcgccgttcg
    43801 agaatttttt gacgataaat gatgaagtat aatctgtgat tttcaaagtc aagatcttgc
    43861 gttttgaacg tagttctctg acttctttgt cgaatacgta cccctcaagt gtgactcttc
    43921 gttcttcttc aacgatactg atcattggtg tcgttggttc atcggctgga atatttcgtc
    43981 ctagctggat gtggatgggt ccttcaagag ctggcgattg ctcttttctt tcctttttct
    44041 tttgttcgtg gacaactaga ctttcagctg cttgcttcat aaaggcttct gcctgttctt
    44101 gtttgcgttc ttcaaaaagt ttcaatactc gttccgcttg ctgctcatcc acttctggtt
    44161 cgatacgaaa ttttgggaat ccgtaactga cgaacaactc ttctactaat ggcaagtatt
    44221 gttgcttcaa ataagaaata gctcctgtac tgtcgattgg caagatgact ttacgatctt
    44281 ttatcacagg tacctgcgtt ttcagtactt gctgtgctag tggtgtatcg cattgctgat
    44341 tttccaaagc ttgggcccag taatcttgca agagctgttc atcgaatgtc tggtcatctg
    44401 ctaagatatt cagtttgact tgtgcaatat ctttaaaagc gatagtcaga tgctgagtca
    44461 atgaccgata tagcataata ggcaaaattt tggaaaaatg cagcgtaaat tcccataaac
    44521 gcgatttacg atggaccact acactatcca tttcaccagc agtaagcagt ggatgatttt
    44581 tttctgcttc ctctagttgg atttgttcca acagtttttc aaataaatct cgtttttctg
    44641 acaaagatat acgccctttc tgatgagaaa caatgcaatt gatcgcatct tatcctcttc
    44701 tttttcagta ccttttagta tactcgtttt ttctgagttt tacattaaaa aattggaact
    44761 gcgattcaaa tcgcagttcc aattttaaaa gcgaatcatc agattgtcaa aaacagctga
    44821 ttcagctatt tttattttct gtgttttaac gcttattatt cgccttggtt caagaggatt
    44881 ggtaaagtat tcaccaattc ttctttacgt acttcaacca tttcgccagt tttcttgatt
    44941 ttcacttcta cgattccatc cactgctttt ttaccgacag tgattctgat tggacagcca
    45001 atcaaatcag aatccgcgaa tttcactcct gcgcgttcat ttctgtcatc aaccagtact
    45061 tcatagccag cttttgtcat cgcttcttct agttcattcg tcaggtttgt ttggtattcg
    45121 tcttttagat tcatttggac gatatgcaaa tcaaatggcg caattccttt tggccagttg
    45181 attccttgtt catctgaatg ttgttctacg attgctgata ataaacgact tacaccgata
    45241 ccataacagc ccataatcac aaatttttct cgtccatttt cgtctagtac agttgctccc
    45301 atagattcac tgtaacgagt gccgattttg aagatatgtc cgatttcgat tcctcgagta
    45361 aaggcaagaa caccattgtt gtctggtgaa ggatctcctt cttgtacaaa acgaagatct
    45421 tcataagaaa gtacagtgaa atcgcgttct ggattcacat ttttatagtg gaatcctgtt
    45481 tcgttcgctc cagtaatggc attcgctaaa tcttggacat aacggtctgc atatactttt
    45541 acgtcatctg aaacaccgac tggtccgaca gaaccaaact cagcacctag atatttttgt
    45601 gcttcttctt ctgttgcttc ttctaaaaag tcagcagata aaaagttttt cagttttacg
    45661 tcattgactt catggtctcc gcgtaccaaa acaaggacag gttgttcatc cgcaatgaac
    45721 aatacagact tgatgatttt ttgaggttca acagaaaaga aatctgctac ttcgtcaatt
    45781 gattttacgt taggtgtagc tactttctcc aattcaagct gtgtttcatg cgattttttt
    45841 gatacatagt agcttgtagc catctccaag tttgcagcat aatcactttc agtcgaataa
    45901 cagatcgtat cctccccgat ttctgagatc gccatgaatt cttttgagtc tttcccgccc
    45961 attgcgccac cgtctccgat aatcgagcga aattctaagc cacaacgctt gaatacttcg
    46021 gtgtaggctt tttcgtaatc tttatatgtc tcgtccaaac tttcttccgt tgcatggaaa
    46081 gaatacgcat ctttcatgat aaactctctt ccgcgaagca aaccgaagcg aggtcgtttt
    46141 tcgtcacgat atttaggttg gatttgataa agatttaaag gtaatttctt atatgaattg
    46201 atttcattac gcatcaaatc agtaaaagtt tcttcgtgag ttggtccaag gatcattttt
    46261 cgatcattgc ggtctttgaa acgatacaag tttggtccat atgtttcgta acgcccggat
    46321 tcttcccaaa gttctgctgg caagatggca ggcatcagca tttctaccgc tccgattttt
    46381 tcaaattctt cccgcataat gcgtttcagt ttttccaata cacgatttgc taatggcaga
    46441 tatgaataaa tacccgctga tacttggcgg atatatccag ctcttagcaa gatttgatgg
    46501 cttaatactt ctgcatcatt tggaacttcg cgtaatgttg gaatcaacat ttttgattgt
    46561 ctcattctat atactccttt atttcctcaa aatagttatc gtttgttatt ataccctatt
    46621 tgtcaacttt ttctagaaaa agaatcgttg aatatcgttc catgtaacta gcaccatcaa
    46681 caacattaaa aatccaaagc cagctaatgt caatattcct tctttttctt gacttaatgg
    46741 tttcccgcga atcccttcaa aaatattcaa gactaatttc ccgccatcta aggcaggaat
    46801 cggaagcaga ttgacgattc cgagattcat tgaaagaagc gccatcaaac taataacagt
    46861 tgttacacct tgatttgctg cttctgaaga caattggtac atcatgacag gtccgcctaa
    46921 tttatctaaa ctgaaacctg taaatagtga tcctaaggct ttgaaaattt ccaatgaacc
    46981 gctgaaagct tgacgcgtcc ctccaatgat cttatccata aaacctgtat tcattggggc
    47041 ttttatacca agttggccaa ctttttcgcc atttgactct acagatttcg gtgtcacgtc
    47101 gacagattgc acctgacctt ctcgttcgat cttaaagtct aatgttttat ccggattttt
    47161 cgtaatgact gttgtcagat cattccatga atggatttct tttccgtcca cactgactac
    47221 ctcatcattt tcttttaagc ctgcttctgc cgcagctcca ttaggcatga tctctcctac
    47281 gcgattagtg ttcgtcactt gaacaccacc ttgcataaat gccagaatga tgaataacag
    47341 gattgccaaa ataaagttat tcatgggtcc agcaaagttg gtcagcatac gctgccacaa
    47401 tttagccgat tggaactgta cgtcttttgg cgcaattctg atttctgttc cgtcgttttc
    47461 aataatcgtc gcatcgtgat caacagggta ggttactact tctgtttcgt ctccattcac
    47521 ataaccagtg atagtcagct catcttctaa atcataacgg ctcaattcca tcgggatagc
    47581 atttgtcaat tggattttct tacttaaatt tatcttctct acgatgccgt cagaatttag
    47641 taaaagagaa agaggcattc ctggtgccat ttctgtttca tcatccccat tgcctgccat
    47701 tcgaacataa ccgccaatag gtaataggcg aagcgtatat gttgtcccgt cttttgcttg
    47761 atgcccataa attttcggac ccataccgat agcaaattcg cgaacgagga ttcctgatcg
    47821 tttcgcaaag aagaaatgac caaactcatg aacaatcact aatataccaa aaacgatgat
    47881 aaatgtcaga atcgttttca tagctttttt ctcctttact tgttttttgt gttttttata
    47941 aaacaacgat aaaacactat aattttacca tagtatacca aagacaccaa tagtatcaat
    48001 ataatgaaaa ataaaaacct gcgtctttta tgaaattcac aaagaaacgc aggtatactt
    48061 actaaataat gccaaataaa tgcatgatag gaaatacaaa cagcaaactg tcgaaacggt
    48121 ctaagattcc accatggcct ggtaagatat ttcccgagtc tttcacatca taatgacgtt
    48181 tgattgcaga ttcgaccaaa tcaccaaatt gtccgactgc tgaaaaaata atcgtcatca
    48241 gaagcatgac aaacatacca tgattaaata gttcttttgc tgggtatagc aataaataaa
    48301 gaaatgcgac tacaacagca ctaccaatac caccgagcgc accttcaatc gttttgttgg
    48361 gcgaaatatc aggacttaac ttatgctgac cataacgtcg accaaccata tatgctccga
    48421 tatcagttgc ccaaacaata aatagaccaa atatcaaaac agccaagctt tctgttcgtg
    48481 cattgacaaa attctggaaa cctattccca catacaagct gacaagcaca ggaaaacctg
    48541 cttcatcaat cgtatacgta tttttagaaa taactgatgt tcctaaaaga atcataacta
    48601 taagataaaa taacataaat gtacttacat tctctggaag aaagaaaaac catctttctt
    48661 ttggcaaaac aagtaacact gcaccaacgg cggataaaac tccttcaaaa cttaagagtg
    48721 tcaatccttt catccgaaac agctcgtaaa ctcctattac tgctaagatt gctgctgtaa
    48781 gctcaaccgc tatgcctccg atccatataa tcggaataaa caagactagc gccacggctg
    48841 ctgtgaccac acgttgtttc atgactgatc ccctttctca tcttctgttt tttttacacc
    48901 gccgaatcga cggtctcgat tttgataaga ggcgattgct tcttcaagat gcgcaccatc
    48961 aaaatcaggc caaagcgctt ttgtaaaata cagctcacta tatgcgatct gccataacag
    49021 aaaattacta attcgctctt ctccacttgt acggatcatc agctcaggat cttgtaactc
    49081 tttaggcaag aaacctgtca ttaaatgctt agcaatcaat tcatcatcga tttcttctgc
    49141 gtgtatttct ccttttgcta cttcttcggc aatttcttgg acagcagtca cgatctctgc
    49201 tctgcttcca taattcaaag caaaattcaa taccattcca gtattgtttt ttgtttgctc
    49261 aattgcacgt cttacagcat cttgcgtatg ttctggcaat acgttttcat aacccatgac
    49321 atgaactttg acattttctt taatcaattc tggtacgaac gtatcaaaga agtcgacagg
    49381 tagttgcatg agaaaactta cttcatcttt tggtcgcttc cagttttcag tcgaaaaggc
    49441 ataaagcgtc aacactttca ctccaagcct tgatgctttt tttgtgactt tctttactgt
    49501 ttccatgcct tctttatggc cagcaactcg tggcaaacga cggttttgcg cccaacgacc
    49561 attgccgtcc atgatgatgg caatgtgctg aggaattggt ccatcggtat taaattgaaa
    49621 ttcgcttttt tcttgaatat atttgttttt ttgcggaaaa aaacgtaaca ttctttttcc
    49681 tcctatactt aaaagattcc cactatctta agtattatag caatatctaa ctgtttttcc
    49741 tatgaaatca ttgttttttt atttaaaaac tgaataattt tttctttttt taatttttaa
    49801 ataaaagaaa tataaataaa aacagaggaa gcggaatgat ccgcccctct gtttttatga
    49861 ttttattaaa cttccaataa ttctttttct ttatcagcag cgatcttatc tacttctttg
    49921 atgctgttat ctgtcaatgt ttgtacgtct ttttctaatc cgcgcaaatc atcttcggta
    49981 atatcaccat ttttttgttg ttttttatat tcatcgatcg catcacgacg gatgttacga
    50041 atcgcgattt ttgcattttc tgcttctttt ttaacatctt tagctaattc ttttctgcgt
    50101 tcttctgtca gttgcgggat aactaagcga atgacatttc catcattggt tggactgatt
    50161 ccgatatcac ttgccataat agctttttca acatcttgaa gaatgctctt gtcaaaaggt
    50221 gtgatcatta aaacacgtgc ttctggaatt tggattgatg ccatttggtt caatggtgtt
    50281 ggcgcaccgt agtagttcac agtaatacgg tccaaaaggc tagcgttcgc acggcctgcg
    50341 cggatttgcc caagttcacg ttgaagattt tgtgctgctt ttttcatttt ttcttttgct
    50401 tctgtcataa ttgcatctgc catttttatt tcccccttac agttgttccg atattttcgc
    50461 ctaagattgc acggcgaata tttccgtgtt catttaaatt gaagacaagc agtggaatat
    50521 cattatccat gcttagtgaa cttgcagttg aatccatgac ttgtaatcct ttggcaataa
    50581 cttccagatg agtcagttct tcaaatttta ctgcatttgc atctactttc ggatcagcag
    50641 aataaacacc gtctacattg tttttagcca tcaggataac atctgcgccg atttctgccg
    50701 cgcgtaatgc tgctgttgtg tctgtcgaga agtacgggtt gccggtaccg cctgcaaaga
    50761 taacgatccg tcctttttct aaatgacgtt ctgctttacg gcgaatatat ggctctgcga
    50821 tttgacgcat ttcaatcgaa gtttgcacgc gtgtcggtac acccacgttt tccaacgtat
    50881 cctgtaaagc taaggcattc ataactgtag ctaacatacc catgtaatca gcttgagcac
    50941 gttccatgcc catttgtgct ccgatttgtc cgcgccagat atttccgccg cccacaacga
    51001 ttgccatttc aacgcccagc tcgtgaactt ctttgatttc ttggatgatt tctttgatta
    51061 ctggtggttt gattccaaat cctgcgtccc cagctaaagc ttctccactc aattttaaga
    51121 ctacacgctg atatttcggt gtgaccatgt tcattcctcc aatattttct attgccattt
    51181 taccatactt agatgatttc gacactctaa gactggtttt tcttgttttg cttaaaaaaa
    51241 gggagcgcac aaaccgtgcg ttcccgtctg ttattcaaca gaattatttt ttcacttggc
    51301 tcataacttc ttctacaaag ttatcttcgc gtttttcgat accttcgcca acttcgaaac
    51361 gtacgaatgt tttaacagtt gcgccttttg atgcaacgta tttttcaaca gtcatatcag
    51421 gatctttaac gaatggttgg tccaccaaag cgatttctgc tttgaatttc ttcaagcgtc
    51481 cttctaccat tttttcaacg atattcgctg gtttgccttc gttcaatgct tgttctgtaa
    51541 gaacagtttt ttcatgttct aattcagctt ctggaatttg tgattcgttt acataacgag
    51601 gattgatagc tgctacgtgc atagctacgt ctcttgcaac tgtttcgtca gttgttccat
    51661 ctagaacagt caatacggca atacgtccgc ccatatgcaa gtatccacca aatgcagcat
    51721 tgtcgtcttt ttctacaact tcaaagcgac ggaagctgat tttttctccg ataacttgag
    51781 ttgcttcgat caagtcagat tcaattgtac ctttatctgt tttgattttc attgcagctt
    51841 ccatgtctgc tggtttgttt tcagcaacaa gttctgcaat ttcttttact aaatcttgga
    51901 acatttcgtt tttagaaaca aagtctgttt ctgagtttac ttcaacgatt gctgcagtgt
    51961 tacctttcac agcaactgaa gccaatcctt cagctgcaat gcggtcattt ttcttcgcag
    52021 cctttgccat tcctttttca cgtaaaagat caactgcttt ttccatgtcg ccttctactt
    52081 caactaatgc ttttttcgca tccatcattc ctacgccagt catttcgcgt agttctttta
    52141 ccattttagc tgtaacgtct gccatgttta actcctcctg tgtgtttttc tttttaaaaa
    52201 aagctgcttc aaaggagagt gaggcttgtc gcccagcctt tgaaacagct ccatcattca
    52261 aaattattct gctgaagaat tgtcgccttc aacaacatct acgatttctt cgattgatgt
    52321 tgctgtgttt tcttctgtga aatcttcttc aactacttga tcttcacctt ggtttccttc
    52381 gatgaaagca tcagccattt ttgaagtaat caatttaacg gcacgaattg catcgtcgtt
    52441 tgaagggatt actacgtcga tttcatctgg atcgcagttt gtatcaacca tagctacgat
    52501 tgggatattt aatttgtgtg cttcttgaac agcaatacgt tctttacgtg ggtcaacgat
    52561 gtacattaca tctgggattc ttggcatatc agcgataccg cctaagaatt tttcaagacg
    52621 ttcacgttct ttgttcaaac cagcaacttc ttttttaggt agaacttcaa aagttccatc
    52681 ttcttccatt gcattgattt gtttcaaacg gctgatacgt ttttggatag tatcccagtt
    52741 tgtcaatgtt ccgcctaacc aacgatggtt aacgaagtat tgtcctgcac gagttgcttc
    52801 ttctttgatt gcttcttgtg cttgtttttt tgtacctacg aataatgcta cgccgccttc
    52861 ttcagcaacg ctcttcatgt aatcataagc tgcatctact aatttaactg ttttttgcaa
    52921 gtcaatgatg tagattccgt ttctttctgt gaagatatat ttcttcattt ttggattcca
    52981 gcgacgagtt tggtgaccaa agtgtacgcc ggcttctagt aattgtttca tagaaattac
    53041 tgccatgttt gtttcctccg atttggtttt atttttcctc ttcttatctt ctaccttgcc
    53101 ggcaaacttt ttcaagcacc taccgacaat ccaataagaa tgtggatttg ctgatgcata
    53161 aagcaccctc agctattata cagacaaaag atccgtatcg caagagcaaa tatacttttc
    53221 tgctcaacat tcaatagttt acctgaaaga taaaaagaat tcaagaaaaa cagtagattt
    53281 ctctttgttt ctttattatc ctttttccat aaaataattt taggtataaa agacgaatat
    53341 tattgggcaa tccttctttt ttttgttatg atacatgtga aatctttcgt aaaggagaaa
    53401 gaaaatgcgc aaagctcaaa gacatttgct gattaaacaa gtcattgaag aattcccgat
    53461 ccgtacgcaa gaagaactat taaacaaact tgggcattat ggcgttaccg ccacgcaggc
    53521 aacgatttct cgagatatcc gtgatctaaa aatcgtgaag gcacctgatg aaaatggcgt
    53581 ttcccgcttc gtattgtttc gcgaaaaagg aactcctgag actaggactg aggaagagga
    53641 tcggctggtt caaatgattg aagacattgt attgaaagtc gaacgagtcc actttttgac
    53701 gatcgtcaat accttgccag acaatgctca tttatttgca tctgttttag atgagatcaa
    53761 acctccctct attgtcagta caattgctgg attcgatacg atcatggtca tctcggaaaa
    53821 tgaggaggac gcaaaacgag tagaagaatt tcttcaccat ccaactgaag tatcactttt
    53881 ttaatcagag cacgtattcc taatatggaa tgcgtgtttt tttattttca atattttcct
    53941 tattgaataa acctttacac tctttacaaa aatacatcat tttttattca aatttttcaa
    54001 caccttgatt gaatcacaat aatcatcatt tatattggat gttaacaaga gcagcttctt
    54061 gctctttgtg tatttcaaaa aagaaatgaa aggaaatcat atgtataaat tattaacttc
    54121 tggaccattg acgacttctg aaacagtgaa aaatgctatg ctgatcgatc attgtacttg
    54181 ggatcaagaa tacaaagaaa ttacacaatg gataagaaaa aaattattgg atcttgctca
    54241 agtatcggaa ggaatataca caacggtctt aatgcaaggt agcagctcct tcggggtaga
    54301 atcggtatta agttctgtga tcaggccaga agatactgta ctgatttgtt caaacggcgc
    54361 atatagacaa cgaatgatca acatgtgcga atgtctgaaa ctgaactata ccgtttatga
    54421 ggtatcggaa catcaaatcc tccaagctca tgtgattaca cagctgattg aagagaatcc
    54481 gtctatctcc gcactagcaa tggtccatag cgagactact tccggtattt tgaataattt
    54541 ggaagagatt gctgctgtca cacaagaaag agatcttttg tttatagtgg acgcgatgtc
    54601 aagctttggt gggataccga tttgtgtagc cgaactaggg attgattttt tgatttccag
    54661 ctcaaacaaa tgtattcaag gtgttccagg cttttctttt gtacttgcta ataaagcgga
    54721 actggaaaaa cgaaaaaatg ttagccgaag tttgtcactt gatctatatg accagtaccg
    54781 cgtgatggaa aacgagaatg gcaaatggcg tttcacttcc cctacccata cggttttggc
    54841 ttttcaacaa gcgctgaagg aactagaggc agaaggagga atcgaaactc gatattcacg
    54901 ttatctcgcc aataatcatg tgctacgaca aaaaatgaca gagatggggt tccagccttt
    54961 cattcaagaa tatcaggggc cattcatcac ctcttttctt taccctaagg actggcgatt
    55021 tgattttaat catttttatc agtatttaaa gcaaaatgga tttgtgatct atcccgggaa
    55081 aatcagcgat catgaatgtt ttcgtatcgg aaatattggc gagatctatc cggaagatat
    55141 tttggaactg acagcaatta tcaaagacta taaggagaac gttaatgatt aaaactgtaa
    55201 tttttgattg ggcaggaaca actgtggact ttggctgtat ggctcctgtc cacgctttta
    55261 gaaatgcttt tctagaaaaa ggaatccaac tgactgacaa agaaatccgc taaccgatgg
    55321 gaaaattaaa atgggatcat atccaacagc ttctttccct cccttctgtc aaaaaacaat
    55381 ggatagctat ttatggacaa ctacctcagg aaaaagaggt ggaggaattg tatcaacaat
    55441 ttgaacatta tctgtttaaa gatttggtca agcattctac cttgaaaccc gacacattgg
    55501 aaacgatcga acggttgaga aacgctggga tcaatattgg ttccacgaat ggatttaatg
    55561 ctcctatgat gacaatcgta gcagaaaccg caaaaaaaga aaggtattca ccagacttca
    55621 tggcaacttt tgaagacgtc gaagggtatg gtcgaccgtt tccttatatg atccataaaa
    55681 acatgcagta cttcaaaaac aagtcggttg atgaagtaat caaagtcgga gatacggtct
    55741 cagatatcca ggaagggaaa aatgccggag tgttgacagt aggtgtaatt gaaggtagtt
    55801 cgctaatggg gatttcttat gatgagtacc aaaaattaga gatggggaaa aagatcgttt
    55861 aaaacagtct gttgctctta gattccaaca agccggcgct gatatttgtg taaacaattt
    55921 aaaagagtta acagaataca ttttgtacgc tgacatgaat ccagaatgac ttttatacaa
    55981 aataagaggt tgtgaaaaag ctgtcctgta tcaagtaata aaaacagcca agcaaaaata
    56041 gctcctcata tttttcgttt ggttaggctt attaccgcag atgcaagctt ttgaacaccg
    56101 tttattcgaa aaaaaaaagg gagctgtgac acgacttttg tcacagtccc cttatttgca
    56161 aacaaacagt gtttaagaga caacctctcc actaaacggt gttcattcag ctgactctcg
    56221 gtatttgctc aaaaaacgat aaaatttgaa aagctatttt ctcttttgtt tctctaatac
    56281 tcggatcaga acgctgattt cacattctct ttttcttaca tcttatctgg tgcatgaagt
    56341 cctagcaaac gaaggtcttc tttcaataat acagtcactg cataaactag agctaagcgt
    56401 gcttcttttt gttcatcatc agctaaaatc ttcgtatgag catagtattt gttgaatgct
    56461 tgtgctaatt tgattgcatg tttcgcaatc actgacggtt cgtatttttc cccagcagac
    56521 aagaccgttt cagggtattt ttgaactaat ttaaccactt cccagctggt atcgtcattc
    56581 aatgcatagt ctgctgtttc tgaagggaca aatcctgctt tttccaacag gctgactgca
    56641 cgagcatgtg tatattgcac ataaggtcca gtttctcctt caaatcgaac aacttcttcc
    56701 aggttaaagt caaatgtatt cagtcgatcg tttttcaaat cgtggaaaat gactgcccca
    56761 accccaactt gtttagctac agcatctttg ttttccaaat cagggttttt ctcgctgatt
    56821 tgttctttag cagattggat tgcttcattt aatacttctt ctaataagac gatctttcct
    56881 ttacgagttg ataatttttt accaccttgc gtgatcaaac caaatggaat atggtgcatg
    56941 tcgtcagacc agtcaaagcc catttccttc aagacagctt tcaactgttt aaaatgatag
    57001 ctttgttcat tccctactac atatagagat tgtttgaagt cgtaagtacg tttacggtac
    57061 aatgcagcag ctaagtcacg tgtaatgtat agtgtcgcac cgtctgactt cttaatcaac
    57121 gctggattca ggtcataagc agataggtca acgatctctg cacctttatc ctcgttcagc
    57181 aaatgttttt cttctaaaag tttgacgatt tcatccatct tgtcattgta gaaagcttca
    57241 ccgttcaacg aatcgaaacg tacttccagc agatcataga ttttattgaa ttctttcatc
    57301 gattcatcac ggaaccattg ccataattga atagcctctt tatcgccttc ttccagacgt
    57361 ttgaaccaag cacgagcttc ttcatttaat tctggttctg tttcagctac ttcatggaat
    57421 tggacgtata aacgaagcaa ttcattgatt ggttctgctt taacagcttc ttctgtaccc
    57481 cattttttgt aagcgacgat cagttttcca aactgtgttc cccagtcacc taaatggttg
    57541 atgcggattg gctgataacc gattttttcc ataatgaaac cgatcgaatt accgataact
    57601 gtcgaacgca aatgtcccat tgagattggt ttggcaatat taggagaaga catgtcgatt
    57661 ggtactgttc cttgattccc gatgttgcta tccccataat gttctttttc tttcactact
    57721 gtttgcaaaa cttttttgct gataagttct ttattcatga aaaagttcaa gtaaggtccg
    57781 acaacttcga ttttttcaaa gttggcagaa tcgatttttt ctgctaaatc tgcagcgatt
    57841 tgctgtggcg cttttcggta aacttttgct aatgaaaagg ctggaaatgc aacatctccg
    57901 tgttcagctg attttggatt ttctagtaat tgctcgactt gttccagtgt taaatcatct
    57961 ttgacagcgt catagacagc ttttgcgaca agatctttat tattcatctt tattcctcct
    58021 aaagtgttcc cttgattgtt aaacaaaaaa aatctctagc gacggcatac ttagtatgcc
    58081 atcactagag acgagatttc ccgcggtacc actccaattg tcctaaaaaa ggaccagctc
    58141 catctgatat cggtagacga ccgtctgttt aaaacagaat tctccaagtg cgcttcgttg
    58201 tatcttcttc attcggcttc caccacttcc gaattcgcta gccaagaatg atacaagtac
    58261 tctcttgttc aacaaatctt agtcttatta aactttcttg aattatatca gaaaaaaaaa
    58321 cgaaaggcta gtcgtttcat aaaaaaacaa tccagatggc ctaaaggaga agaaatacca
    58381 cctggatagc tataaatcat ttcgtaaata cgaaagactt aacaaattaa tcagctacga
    58441 taatcgttcc ttcttcagaa gctaaaagat tctcgatatt ttctaaagaa gtgatgattg
    58501 ccttagcgtt tggttttgct tcaacaaatg caatagctgc ttctactttc ggaagcatgc
    58561 ttcctggagc gaattgcttt tcatcaatgt attgtttcat ttctgaaaca gtaacagttt
    58621 ctaatttctt ttgatctggt ttttggtaat tgacatacac attgtctact cctgtcaata
    58681 cgatcagcaa atccgcatcg atgatttcgg ctaatttttc tgaagcaaaa tctttatcga
    58741 ttacggcttc tcgtccttct aatccagtag ctgtttctac aacaggaatc ccaccgccac
    58801 caacagagac tgtgataact ccttgatcga ccagcgtttc gatgacacgt gcttctttaa
    58861 tcgagatggg tttaggggaa gcgactactt ttctccatcc acgtccagca tcttctttga
    58921 atgtcacagt ggagtcagca ttcatttgtt ctttggcttc ttcttccgtg tagaatggac
    58981 cgactggttt acttggattt ttgaatgaag gatcattttc atccacaata acttgagtga
    59041 ctaaagaaac cacatcttta tcgatccctt tttccttcag tacttcgccc atggcgtttt
    59101 gtaaccagta accgatagat ccttctgtca ttgcaacaca tgtatctaaa ggcattgccg
    59161 gtgttttctc agaatcagca gcttgctgct gaatcaatag gttaccgact tgcggaccat
    59221 ttccgtggga gatgatcaat tcatctcctt gttcgataaa tttcactaaa tactttgctg
    59281 tttccattaa cgcttcttgt tgggcttttg cacttgcatc cgtagacaag atggcattgc
    59341 cccctaaagc gacaactact tttcgtttgg ccatttcatt cgtcctttct tcagttctac
    59401 cgaattttct agataacaaa acgagccagc gttttgtgat tttccctcaa tgctgactcg
    59461 ttttttcgtg agatgaatgt ggttatgctt aaacgcgagg gataaacaag ttacctaatg
    59521 ttgctgccat gatcgctttg attgagtgca tacgattttc tgcttggtca aattgacgag
    59581 catatttgct gcggaagact tcatctgtta cttccatttc agtgatgcca aagcgttctt
    59641 tcatttgttc accgtaaaca gtgtttgtat catggaaagc tggcaagcag tgcaagaaga
    59701 tcaaacgatc tgtgttgtgt gttttttcta ccatttccat attgatttgg taaggtttca
    59761 acaatttgat acgttcttcg aatttatctt cttcacccat tgatacccat acatcagaat
    59821 aaaggacgtc tgctccgtct acacctttat caacatcgtc ggtaatcatc aattgtgcac
    59881 cggatttttc agcaaagcct tctgccattt tgacgatttc ttcttcaggt tgtaattctt
    59941 ttggtgcaac gatacgcata ttcgctccta aaattgcacc tgtgactaat aaagagttag
    60001 ccatattgtt tcgaccatct ccgcagtaag caacagtgat accttctact gttccaaagt
    60061 tttcttggat agttaaaaag tcagcgatca tttgtgttgg atgccattca tcagtcaagc
    60121 cattccaaac tggaacacca gagaattctg ctagttcctc taccattttt tgactgaatc
    60181 cacggaattc gattccgtca aacatacgtc ctagtacttt agctgtatct tctgtggatt
    60241 cttttttacc taattggata tcatttgcac ctagatattc aggatgtgca cctagatcga
    60301 tcgctgcagt agtaaatgca gaacgagtac gtgtagatgt tttttcaaat aaaagcgcaa
    60361 tattttttcc ttctagatag tgatgtggga taccacgttt tttcaagtct ttcaagtgtt
    60421 ctgaaaaatc gatcaaatat tgtaattctt cttttgtaaa gtctttttct gctaataagc
    60481 ttcttccttg gaatactgat tctttcatat taaacattct cctttagatt gtttttattt
    60541 aagattaaag aggaaatccc gacggcagct gacagtaaga ctgccgtcag gaaacaaatt
    60601 acttcaagtc ttcacggaca agtggttggc tcatgcagcg tggaccacca cgacctcgtg
    60661 acaattcact tgaattgatt tctaacactt tgatgccata gctacgaagc aattcgttcg
    60721 atacataatt tcggttataa gtgactacaa cacctggagc gattgccaat gtgtttgatc
    60781 catcattcca ttgttctcga ggtgcaacga tctcatctcc attaccagtt gggatcagta
    60841 caagatcatc taatccaaga gcagctttca tcgtttcgtg taagttatct gaatgagtaa
    60901 tcttgatatc atcaccatct ggttcgattg taaagacatc catcttaccg tctttacttt
    60961 gaattgctgg atggatagtg aatttatcgt gatctaccat tgtaaatacg gtatccaaat
    61021 gcatcattgc acggttgttc ggaattttga ttgccaacac tttttcaaat cctgaatttt
    61081 ttgcgaatag gtggcgtgct aatttttcta aagctttcgc attagttcgt tgagaaatcc
    61141 caacagctac tactttatcg cttaagatca attcgtctcc gccttcgata tgatctggat
    61201 tttcacgatc caaccatact tcgattcctt tatttgcaaa tcttggatga tgtttcaaaa
    61261 tatattctgt aaacatcgat tcacgacgac gtgcttcaaa agtcatctta ttgactgtca
    61321 tcccatttcc cattgatgcg gaagggtcgc gtgtaaagta caagtttggc attgggtcca
    61381 tgtaaaatgg atagtcatcg tctgctgaca gatcatatag actgctagaa cgtacttcga
    61441 tatcttttgt acgaacccca gccatgattt tatctaccat ttcttgcgtt tccattgata
    61501 gaaggaactc atgaagaccc tctcttacag cattcgatgc aatatgagat tcatccaaca
    61561 ttttattcaa gaattgttct ttgacattgc ctgcgtcaat cgcttctgcc gctaattttt
    61621 ccaagtaaag agtctcgacg ccttcatttt gcaatgtctt cgcaaagttg tcatgttctt
    61681 cttgagcaat cggaagatat ggaatatcat cgaacaacag acgatccata atatctggtg
    61741 tcaaattttc cacttcttgt ccaggccgtt tcagtaaaac tgtctttaat ttccctattt
    61801 cagagaaaac gtgaataggt ttatccatgt tgtgttgcct ccttcttttt gattacatgt
    61861 ataggatatc ctccttttgt aatcactttc ataattttgt ctcattcaaa atgagacatt
    61921 cctcacatta atattcgata attaaataat taaacgtttt tctattttta agcgtaattt
    61981 attcattttt tattctgtat acactttcaa aaaaatattt attcattgaa aaaatttttt
    62041 tgaataaatt aaaaaaataa attatattat cgttgttagc gtttactata tgtattattg
    62101 ttgtttttta tacacaaatc attcgcttca aaacaaatta ttcaatacca ttgtatattt
    62161 tttacataat aacaaattat atttgtaaag tattaaaact tgtttctaat gttggtatgt
    62221 taaaacttta caaattcttt aaaaaaagtg acaataaata tagtgaacaa taaggagagg
    62281 actttttaat gcgtgttaat aaaatcgatt ttcacttttc aaaactcaga tatcaacctg
    62341 attttgaaca tttctcggat gaagagttcc aacagatcaa ggaacatact gttcttcgtt
    62401 cttataaaaa aggacagatc cttttcgacg atggtgatcc cagacaacgg ttgtatatct
    62461 tgaccaaagg actcgttcgt ttagaacgtt atgatgaaag tgcaacttat tactactatg
    62521 actatgtgaa tacaaataac ctttttccta tgtcaggaat gtttggagaa gagacctaca
    62581 cttatacagc tcaagcgatg actgatattg aaacattcta ccttcctgtt tcctactatg
    62641 aaaaattagc acgaaaaaat cccgaacagt tgatctatat gatacaaaaa atttctaaag
    62701 tagttgaaat acatgaattg cgtatccaaa tcggattgac ctctagcgcc tttgaccggg
    62761 taaaacaaaa tttattcatt ttgaaagaag aattgggcgt accaacaaaa gatggtcata
    62821 tcaccattcc ttatccgatc accttaaaag aattagcagt gaatagcggc acgacacgtg
    62881 aaactgctgg acaagtaatc aaacaactac gtgattccgg gctgttagat tatgacaaaa
    62941 agcgttttac tttctgtaag acagctacta ctccagctat gagagaataa cgcgaacaaa
    63001 aataagcagt gaccctgata aatatcaggg tcactgctta ttttcctccc taaaacttct
    63061 gaaagatccg gcagttttag atcactggac aagactcaaa gattttctat gtgtgtttca
    63121 gttatgtaat attcactgtt tgcaaaaaat actgttagat taactagatg aagcgtcttg
    63181 tcctcatccg atctagatta ttcgatattc ctcgacaata aacgattact cagtgagggc
    63241 aatcagagga acggataatg ataaataagc tgtaaaaaat agcaaaataa caataatgat
    63301 taaaagtatg taaaaaatag ggctttgaca aaaacgtgtc acagccctat ttcgattaaa
    63361 cggtgtgtac ctgtcaactc ttcggtcaca agtcataatg ttcataaaca tgaggagctg
    63421 ttttttgaaa ttgttccttg tgaatcagag ttaaacgaca ggcttacgaa ctcttgatta
    63481 aacggcgttc aaaagcttgc atacgcggta ataagaacag ccaggtcaaa aacatgagaa
    63541 gccgtttttc ctgggctgtt cttattactt gatgcagggc agctttttca caacctcttt
    63601 attcagataa aaccaagctt ggatcagcat tcaactgata gctagcaaaa tttctttttt
    63661 gcatttccac atgtgctgct gctccaatca ttgcagcatt atctccacaa agtcgaagag
    63721 ggggaatcac tagttctacc tcagggagtt tagctgccaa agcatcctgc aatccttcac
    63781 gcaacccttg attggccgct acacctccag ctataatcag ttgcttgact ggataatttt
    63841 gacaagctcg aagtgtttta gtaatcaata catcgatcac acttgcttga aagctagctg
    63901 ctaaatcatt tttgtctaga tcttctccac gctgttgtgc attatgcacc aaattgataa
    63961 atgcactttt taatccgcta aaactgaaat cataattatc ttcatggatc atcgctcgcg
    64021 gaaaatggta attatctttt ccctgatgag ctagctgatc gatttctttt ccgcttgggt
    64081 aagaaagacc taatactctt ccaactttgt cataagcttc tcctgctgcg tcatctcttg
    64141 tctccccaat gatttcatat gatccatctt cttgcatata gactaattct gtatgtcctc
    64201 cgctaacaag aagtgccatc aatggaaact ggaatggttt aaccagacgg gctgcataga
    64261 tatgccctgc catatggttt acaggaataa gcggcaattg gtgtgcccaa gcaaaagcct
    64321 tagctgcaga aataccaatc agcaacgagc cgacaagtcc tggtccataa gtgacagcga
    64381 ctgccgataa atcttctgcc gacacaccag cttctaccag tgcatcttcc aagcataagg
    64441 tgatttgttc tacgtgatgg cggctagcta cttcaggtac tacgccacca aaacgtttat
    64501 gactgtttat ttgagaagca acgatgttag ataagatctc tgttccattt ctaacgaccg
    64561 ctacactcgt ttcatcacaa cttgattcaa tcgccagaat caattcttca ttcatttcat
    64621 cgtctccgtt tttaactttc tgctcataat gatcgcatct tccgtcggat tgcgataata
    64681 tgatttccgt ttacctaata tacgaaactt ttctgattca taaagttttc ttgctgcttc
    64741 attagataga cgtacttcta aaaaaacatg cagcgaatct tttatttgtt ccgtaatcag
    64801 taattgtaac aaatgccgtg catgcccttt tccttgttct gaaactgcaa cagcaatatt
    64861 tgtgatctcg acttcatcta ttactttcga gtatccaata aagccacaga tctggttatc
    64921 ttcagctaaa agcagataat cagagtgagg ctgttggatg tctgccaaaa actgcatttt
    64981 cgtccaaggt gaaccatgtg gataagcatt ttcgctaatc atccatacgc attctgccaa
    65041 gtacgcttca tcaaaatctt tttttctgca aatcaactaa tctcactcat tttctaaaag
    65101 ttttatcata tccaacgcat cttcttttgt ttcagtgtaa tatctttttt tgatcgttgt
    65161 tgcttgaaac cccaatttcc gataaagtct ttgtgcatct tgattactca tacgcacttc
    65221 taatgacatc gtctcacagc gattcattat agcaaagttc tcgatttcgt caataagcag
    65281 cgaaccgatt cgtttacgct gatatgccgg tcgaacggca atattcgtga tatggcaatc
    65341 taaaccgaac gctcttgaac cgataaaacc aatcattctt ccattatcaa agatacctag
    65401 atatagatga ggaagcggtg acttcaattc tgatataaag gcactttttg tccatggcaa
    65461 ttcgccatta tagacttctc gttcgacatc cagcagctct ttgatatctt ctgtagtcaa
    65521 ttctcttagt acgtaacgac gatcgatttg ttcgactgtt ttttctgtat aaatcatttt
    65581 atcttgaaaa aagcttctgg catacgctct aaattttttc aacataactt tcgtctccag
    65641 gtgtgtgcgt ctccaaccat ttttcttctg cttctactcg ttttaaatag cgaggaagaa
    65701 aagcttgttt ctctgcaact ggttcaacta aagcacctaa ttgagccaca gttacaccac
    65761 ttggaatatc ccatgctgga actgtattaa tcatcgcact aggcaatatt tcctttattt
    65821 cagagaagaa tttgtgacaa tcactcccga cgaaataaat agcttcattc agcttttgta
    65881 gttgtgtgaa caaatcagaa gcagaaatat gtacatcttc aagtacagtt tctaatctat
    65941 tttctttcca gcggtatgcc ccagcgtata cattttttct tcgagcatca aacatgggca
    66001 caataatatt atccacaccg atgcaattag ccgcgatggt tttcagacta gatactccta
    66061 ctagctcttt atctaatgta taagcaatcg tttttgctgt cgttacacct atacgaagcc
    66121 ctgtataaga accgggacca tcagaaaccg cgattcggtc aatgtctttt ggacttattt
    66181 gaagatctgc aaacaattgg tcgattgcag gcatcagtgt tacactgtgg ttgcgtttga
    66241 tatttgtttg tatttgtcca agaatttgtt cgtcttctac cacaccgatc gccaaagttt
    66301 ggtttgcagt atctattcct aatgtaatca tatatttgat cctttctgct atgacattct
    66361 cgccttccat tgtagcatac ttttttattc tgaggatgaa aataccaaag gcaaaactag
    66421 tacaataata catgattatc tgctggcggg caaattttgc cccttcctga aacacaaaaa
    66481 agctgcggta tcactccatt ttcccacagc ttttccatct tttatttcgt tgattctcga
    66541 ataatcaact ctgtttccac aataatcttt cttgaaaccg gtgctttgga attacttaat
    66601 tgaagaatcg tctccactgc tagctctccc atccattcgg tataaacttt tacagtagaa
    66661 agcgagggcg ttacatattt cgctacactg acatcattga agcccatcac agaaatatct
    66721 tctggtacca ctaaaccttt ttcttgaatc gctttcagtg cgccaatcgc taatgcatca
    66781 ttagctgcaa aaagcgcatc aggaacatgc ggattcgttt ttaaatattg cttcactgct
    66841 tgatatcctg actcgacaga aaaatctgct tcgataattg gaccttcgtc gtagcctttt
    66901 tctgccaaaa cttgttgaaa tgccataatt ctgggatctt ttagccgctg atggtttttc
    66961 ttcgtatatt ctgttccagc aagcatagcg atatgttgcg ctttatggga gacaaagtgt
    67021 tcaatgactt tttgaacact tgacttaaag tcgacaacta gagagtcgat tccttgagaa
    67081 gtgccgtcag aatctaccaa aagcaaggca ttttgggatc ctttcatttc taataactga
    67141 gcttcgtcga attttcctag tgcgatcgtt ccatctgccg gaagatcact aatggaatcc
    67201 cacgtttctt tcaataaagt aacgtttgct tcttctgcct ttttttcgat tcctaggcga
    67261 atagataaat aataaagatc ttcaagctct tccgtatcgt cgtaccactg gatcaggcga
    67321 agcgtttgct tagtatttgc tgcattttta cgatgtttcg tataatttaa gcgttctgct
    67381 gcttcaaaaa ttttttgctt tgtggctaag ccaacggaaa gatcaggatc atagttgaga
    67441 actcttgaaa cagtagcagg agaaactcct gccaactgcg caatgtcttt aattgttgcc
    67501 atttgtctct cctccttttt tacgtttata aaatcgcagt aaatcgttca aacgctgcct
    67561 gtcctttttc atctcgcttg aatactccag cgtcttccag tacacgtgca aaaacctgac
    67621 ctacagattt ttgtacgaca tcggtgaccg tatctttcgt caaatcagga tgttcttttt
    67681 ttaattgttc tgcccacgga cgatgatatt cagccatctg gttttcttct cctaataaga
    67741 aatgctctac ttctactagt tctggtttca aacgaggtgg taaaacagca agccccatta
    67801 cttcgatcaa cccaatgttc tcctttttga tatgttggac atctttatgt ggatgaaaaa
    67861 tcccatcagg atgttcttct gaaacattgt tgtctcgaag gacaaggtcc aactcaaagt
    67921 aattgtccct tcttcgtgca attggcgtaa tcgtatggtg tggtgtacca tctgctgaaa
    67981 aagctctgat agatactgtt tcatccgaat atgctttcca tttttccaat actgagttag
    68041 ctgcttcaat aagcaagttt ttctctgttg attgcaaacg gatcacagac atcggccatt
    68101 tcacgactcc tgcgatgact tgcggataat cttctagttt gataagtttt tctatcggtg
    68161 cttttgccat aggaaattca tgacgtcctg cctgataatg atcatgagaa agaatcgatc
    68221 ctccaacaat tggtaagtca gcattcgaac caacaaagta atgaggcaag acttcagtaa
    68281 tccgaagcag tctagcaaat gtttcctttg tgattttcat cgggcggtgt tgttctgata
    68341 aaatgatcga atgttcattg taataagcat aaggggaata ttggaatccc cagctttcac
    68401 cgtctagatt cattcgaata atccggtgat tggtgcgggc tggatagttc aagcgacctc
    68461 tatatccttc gttttccatg caaagcatgc aggtaggata gtctactttt accgcctcgc
    68521 gttctgctgc gatttgtttt ggatcttttt ctggcttaga taaattgatt gtgatttcca
    68581 gttcaccata ctccgactct gccggaaatt tgatgttttt tgcgatggct cttgttttga
    68641 tgtagtcatt tttcttactt aaattaaaga aatactcagt tgcttcctct gggcttttcg
    68701 aatagtgctg tgcaaagaat gcattgacga ctgaaggtgg cggtgtgaga aaatccatta
    68761 attgcgcttc aaaaatctct tgttctgctg gcaattctga aagaacacca ttttctcttg
    68821 ccttagcgac aagctgatcc aataagtcta cagattcttc cttaactggt cttacttcaa
    68881 tgctttctag agcatcttct cctaccatcc ctaaaagacg attctgtaaa tataagcggt
    68941 ccatttccat ccatccgcca gcttcgatcg caagtgtggc aaaatcacaa atcgtttgac
    69001 tgattgacat atctcattcc cctattcttc ataaccattt ggatggctga catgccaatc
    69061 ccatgctgtt ttgataatcg ctttgatatc tgtgtattca ggtttccagc ccagaatctc
    69121 tctcgctttt tcacttgaag cgactaatcg gctaggatct ccagctcttc ttggtgctat
    69181 ttctgctgga atttcttttc ctgtcacttc tctagctgct tctagcattt ccttgactga
    69241 gtatcctttg ctgctgccta aattgaagaa gttgctttca tttccttctt tcaagtattc
    69301 caaagctaaa atatgtgcag caatcaaatc ttctacttga acataatctc tgatacatgt
    69361 tccatctggt gtatcataat cgtctccata aacagccaag gcttttcttt gaccaagagc
    69421 tacttgtaaa atgattggga caagatgcgt ttctggtgta tgatcttctc cgatagatgc
    69481 atctgctttt gctccggcta cattgaagta gcgcaaagcg acatagcgca tgccatatgc
    69541 ttggtcacac cacttcatca ttttttccat catcaattta ctttcaccat acggattttt
    69601 aggattagct ggtgtatctt ctgtgattgg agactctttc ggctctccat aagttgctgc
    69661 agtagaagag aatacgattt tattcacgtt gaactcgtgc atgacttcaa gtaagatttg
    69721 cataccgtat acgttgttgt tgaaatacat caatggtttt tcgacagatt ctcctactaa
    69781 agagcttgca gcaaaatgga ttactccttc aatcggttcc ttttcaaata cggaacgtag
    69841 aaattcttta tcccggatgt ctccttcata aaaatgagca tctggatgta ctgcttgttt
    69901 gtgacctgtg agcaaattat ctaccacagc tacttgatac cccttttgaa ctagctggtc
    69961 tacagcgtgc gaaccgatat aaccggctcc gcctagtact aaaattgtca taaaaaacac
    70021 tcctttgatt agtaaaattg tgtttgttga ttctatataa tttaaaaaac gaagtttact
    70081 tttatggtga aaacaaacaa agtaaaattt cgtaaattca tatggtaaat ttataataaa
    70141 acatttagta aacattttca agggtttttt gcaaaggttt acaaacaaac gtaaaactag
    70201 cctttttttc tcttttgttc cataatagat ataacaaata ataaatgagg tggattcaat
    70261 gaaaaaattt gtatctggaa tattagtagg aagtctggca acagccgctg ccgttgctgg
    70321 tttggttgct tctgtgaaaa aaacagtgat cgatccaatt gacgaaaaag aagcaatgat
    70381 cgaagaaaac cgtaaaaaag caatgcgtaa acgcgtttct cgttaataat tatttaaaaa
    70441 tacgcatgaa gactttctaa aaaacagata agtcatcatg cgtattttta tttgtcagtc
    70501 aatataagtt gtgctatttt atctgcctgt ctcagattcc atggatctgt ataaggtcta
    70561 gctactgctg cagttagcca atccacacct tcaacaggta ttccatagca ataaaagtca
    70621 gactggattt cccctgaagc atcaatcacg cgattcgtac ctcgctcaac atctatagct
    70681 tctgaatgat aacttcctgt attatctgaa aatgaaaaag ggcgaacaag tttgttttcc
    70741 ttcaaatttt ttatgacagg attacttgaa cgagaaaagc ttgtttgtgg caatcgagct
    70801 tcaatcaaat agcgactgct gatttcttta tcttgtagag aaataacata gcggttgtgc
    70861 ttttgctgaa tatcaaatgg cggttcgatc aaatgaaaaa tacccgcatc tatcagtgct
    70921 gctaattctt tcgtccgaat gattggcgga ccgatcgtta aaaagctatt tagatgagta
    70981 aaccatcccc atagtatttc tttgtattcc ttagcagaaa aaacgtgcca ttcaatagcc
    71041 tgccggattg gatcacgcca gtcttttaat gcatcaaatg ttgaagcaaa tgctcctgtg
    71101 caattgcctt tttccgcttc ttttatctgc ccttcaataa atattcggct agcttctgaa
    71161 aagggctcat tctgataggc aagaggagtt tctaaatacg accaatccca tctataaggg
    71221 attagtgctg gatgctttcc gagacactcc tctgaagaga gggagagaaa atcatgctca
    71281 aaatttttct ttggaatcgg caagtgatat tcttcgatga ttttcttgta ataaaacaac
    71341 tcaacgtctt ttttcagata gtcaaaaaat gtttcgccag tcaaaaatcc cgactgatgc
    71401 cattgctcca ggttttcttt tgttagtaac cgtggccatg ccattgctcc gccttgcttt
    71461 tgatttcttc ctcgagggta ataagggagc ccccttcttg atccactgta tacaatcggt
    71521 tccttgcctg atggatgata gaccagtttt cccttttcgt tctcgaagcg ccctcctctt
    71581 gatactgtaa acaatccgac ataatcaaaa aaacttaagc ctagacctct taaaaagaca
    71641 ttttctttag gcggtatctt cgaaagatct acatctgcag gattagaagg aagctgatac
    71701 agtaaaacat ttttctttgc gtagtctacc cacactcttt cttcttctgt ctcatcattt
    71761 tcccagtgac cgcttgctaa aacaagctga tcgatagaat agctttgctg atctgtctgt
    71821 aaaagataac catcttttct tttgcttact ttttttacta aagaataaac aaactgaata
    71881 gaagctggaa attcttcttg caactttgag aaaaaccagc gttgatagag tccgtataaa
    71941 catcgagtag attgctgatc tttttccaga cgattgattt cttctataat tagttgctta
    72001 tttttggtta ccgtctgttc gatataatct gtagcaggtc ctttactcca ttgaaacaag
    72061 ttgggtccct gtgttaccaa tcctccactg gacaatgttt catctgtaaa aagcgtcact
    72121 tgttgagaaa cagaattcat taataactcc ggtggctgat tcaaccgcca aactcgacct
    72181 ccaggaccat tgggatcgaa aagaaaaagt tcaagagaat gtctgtcctg attattatgg
    72241 agaatccttt ctgctacact taatcctcta ggtccggcac caatgatccc tattttcatt
    72301 tgcatgcctc catttcgata aattttttca ataaaacagc atggttctga tgttcatttt
    72361 ttgcaccata aacaaaagta atgactggat gttctttcat aagttgactg agtttaaaaa
    72421 tagcttgctt cttttcttct tcgaaaatca attcttgctg gtatttcttt gcaaatgaag
    72481 caaatcgttc tggtacatgg tcaaaagttt tgcgtgcttc attactaggt gcaatttctt
    72541 tcaaccacag atctaactgc gctttttctt ttgaaattcc tcgtggccag aatctatcca
    72601 cgagtattct atagccatcc tctttttcag catcaaggta aacacgtttt aatttgatca
    72661 tagttgtttc cttctttcta ccttttcgct tagcttatat atgtagataa tagcacaaaa
    72721 taaaaaaaat gaacggcaca actatccatt gcgccgttca tgtgatcttg gtcaaaatct
    72781 aatgattgat tcggttttta aagctgtcat acaatcatct gttttatact tttttacttt
    72841 tgatttttcc agaccatccg tcatatccac ccttaagtaa ataaatctct tgataacctg
    72901 ctttacgtaa tttatttgct gtacggatgc tcaaactttt cttttgatcg taaatataga
    72961 caggctggtc ttttcgaata gatcctaatg aatctttcaa aacagtgtaa gggatgtttc
    73021 ttgcacctaa aatatgccca gcatcaaaca catctttttc gcgaacatcg attacttgtg
    73081 cttttctcat tccttctcga aattcttctt ctgtcaaagt cgttgctgaa cgtttggcca
    73141 ttactcgtag atagacttcc caaaggatga ttgcaagcac aatcaatagc aaaatgatat
    73201 taattaccca taaaaccatg taatgcctcc gtttttttaa gcaaatttca aggctaatga
    73261 ggcagcacca atgacaccag cttcattacc aagctctgct aatttgattt ttgttgattc
    73321 tcttacttgc gggaaagtaa attctttaaa atatttctct acacggctac gtaaaaattc
    73381 tcctgctgcc gatactcctc cacctaacac gatacttgac ggatttaatg tattccccaa
    73441 gtttccgcaa gctaaaccta agtagaagca tacgcgatca acaaccatca atgcaaacgg
    73501 atcgtcttct tgagccattt caaagatatc tttacttgtt acttcttctc cgttgtctag
    73561 cattgctttc agttttgaat cccctgcgta ttcttctgcc aagaaacgac ctaggcgtac
    73621 cacacctgta gcgctagata cagtttctaa acatccgcgt ttaccgcaag tacattcgaa
    73681 cccttcagga tccacagtga tatgtccgat ttctcctcca gctccgctca cgccgtgaat
    73741 caaatttccg ccagcaacga tacctccgcc aacacctgtt cctagagtaa cgaatacaac
    73801 gtctggatcg ttttctccag cacctttcca tcgttcacct aaagcagcaa cattcgcgtc
    73861 attatcgata gcgaatttga ttcctgttcc tgcctcgatc agttttttca caaattgaac
    73921 ttctgtccag tttaagttat acgcaccaat aaccgttcca gcttcgctgt ccacgcttcc
    73981 tggggtaccc atgccgattc cgataaagtc ttcggctttc atattatata aattcaaacg
    74041 atgattgatt gattcaatga tttcaggaac gatatgctta ccatcatcca aaatattggt
    74101 atcgatgctc catttttgct gaatctctcc ttctggtgtt aaaattgcaa attttgctgt
    74161 tgttccacct aaatcaatcc caataatctt cttgtccatt acaaatttcc tttctttcgg
    74221 ctttcttcaa ttcggtgctc tctttttaat atgcgccacg ctgtcatgta tgtatcatga
    74281 tcaatcaaac ggctatcata cagattacgc aattcgatag tcattaattc aatgtcatag
    74341 atgcgtgcac ccacatagat aaagatgcca aattttttga acagctgctg tacatcatat
    74401 aagctctcca tctttaagca cttccttcat attatacaag taaaccatat ttttttaaac
    74461 ccagtaaaat acatattaca aaaagaaata caaaaactag tgtagaaaga atcctttggt
    74521 gtatcgaata gcttgtctgt tgtttcggta gacccaaaac attccctaac actaatccgc
    74581 caattagccc accgacatgt ccccaaacat ctacagaggt atccagaaga ccaaaaacaa
    74641 atgtcaacac aataaataaa agaaaatgtc tgactagctg ctggatcgct gggttatgtt
    74701 taaaatgaaa ccctaagata aacaacgcac cgaacaaacc gaatatcgaa gtacttgcac
    74761 caccagacag aacattcgct tcgttaaaag caaagcttgc tgtatttccc attatcccgc
    74821 tgaacatata aatcaagaaa aaacgccaat ggccatagat tgcctcgatt tgctgcccca
    74881 taaaatacag tatcagtgag ttcattacga aatgcatcag tccaaaatgg atgaagattg
    74941 gtgtcactaa acgccaccat tcattgaagt gaacaagata aggaccatac attccggcat
    75001 aataagggat ctcaagtcgc ggaaataatt ccatcatgag gaagaccgct gtctgtatcc
    75061 ctaaaaaagc ataggtccat aacggtcgtc ttaaccatgc acgcaatttt atttgctgtt
    75121 gataattcat gaaaacctcc catttcattt tagtcaataa acaattgttg gatcttctga
    75181 tcaaagctct ccggttgcca ttgttcattc aattgttcac gaaaaacaag gctacatgtt
    75241 tttttatgaa aattatttaa ataccggtcg taataaccac cgccaaaacc gattcgataa
    75301 ccggctctat tgtagataat acctggtaca atgaggagat cgatcatctc cggcaaatag
    75361 agcttctctg attgtggctc aagaacacca aaactcgaac gtacaagaac ggactgttca
    75421 tccatttcat aaaacgccat ctgacgtttc ggcaaagttt taggtacaac tattttcttt
    75481 tgttcttttt ctgctcgttg gataaccggc tgtgtatcca gttcaaattc attcgataaa
    75541 gtcgtcccta tcacttttgc tgacttccag tactcgctgg cgaatagctg tttatagatt
    75601 cgctgttctt tttccttttt cttgccactt ttggccagat ttttcagctt ttcgattcct
    75661 ttccggcgta atcttacttt caattggtcc aaaaactcac ccttccttct ctcataaaat
    75721 ggtataggaa aaaaagaaaa atagcaatcg aactttcaaa taaatgcata aatagaataa
    75781 aaagaagacc tagaaatgat tggccttcct tttttaatga atttcaactg ttcagcgcgt
    75841 gtttttgtct gataaaaagt gcatacagaa aatatggcgc accaaaaagg gcaatcaaaa
    75901 ttcctgtagg tacttcccca cttggtagaa tcactctagc aaccatatct gcactaagca
    75961 gaaaaatgga accgaacaaa ccgctcagaa caaaggtcca gttattttct ttacgtacga
    76021 ctagcttcgc agcatgagga gctagtagtc ctacaaaaga taaactacct gtcaccgcta
    76081 cactaccgct tgccaaagca acagctaaca acaaaaggat tttttgactt ttagccacgt
    76141 taaggcctaa tccttgcgcg cgttcttgac caaatgatag caatacaatc ctctgtgcat
    76201 aaagtcctcc tagcggaatt aagataaccg cccatggaag caatgcccaa acataaggcc
    76261 agctcgcacc ccagattgat cccgctaacc atgcattcac aaatccataa ttttccttag
    76321 ataattggat cgtgcatagc aatgttaatg cagaaaggcc ggcattaacg gcaataccgg
    76381 acaataagat tcgattcata cccaaaaagc catttcgatc ataggccgca agatagacac
    76441 agcaagcagc taaaacacca cctagaaagg ctacaactag caatagaaac ggcagcgaat
    76501 agtgcgaaaa gaaacctaaa taaagcatca ctaaaaatcc tgctccggca ttaatgccca
    76561 atatactaga atctgccaat tcatttcttg ttactccttg caagatataa ccagaaacgc
    76621 caagacaagc tcctgctaat aaactgatca gtaatcgagg aactcgaaat tctctaacaa
    76681 tcagcgccaa agaagatgat tctttcccta tgaacgtggc aaaaagctga tccaggtaaa
    76741 taaaaggcgt accaatcatt aaactaccta tagacaggat gacaagtaca aaaagcaaga
    76801 aatagaacgt ccaatatatt tttttcaccg ttgttccctc cttacttgta tcagtaaaaa
    76861 cggaacgcca atcaatgcaa tgactaatcc aaaaggtgtt tcaaaagggg gattgatcat
    76921 cctcgctgta aaatccgcca acataaccaa tccaccgcca actaaaaaag agacaggtag
    76981 aacataacga tagtccgttc caaccattcc gcgaacaact ggcggaacca acagcccaat
    77041 aaatgaaaca ggtccgacta acgaaacggc aatggctgct aacactgcaa ctagacagaa
    77101 aacaatcaac cgcgttcgtt taggatgact tccaagagct aatgcatgtg tttcactcaa
    77161 atgaatcaaa gatattgctt ttcctaatga aaaagaaacc aaaacagcaa gtatatataa
    77221 aggaaacaat actgctaatt gtttccatgt gatattggca gctccgccta caaaccaaaa
    77281 agcaagatcc tgctgcagat taaagaattg ggtaagtgct tggctgatag cagtaaaaaa
    77341 agaactaata gctacgccag ctaaaatcag ctgtaaagga ttcatgccca ttttcgaaaa
    77401 ctgcaaaaaa ccaaatacga gcaaagttac agcaaaagaa cctgccaatg acattagaaa
    77461 cacagaaaaa tcagaagctt taggccaaaa agcaaaacta agggccattg ccaacgaagc
    77521 acccgcgttg attcctagta agcctgaatc tgctaaagga tttcttgtca ctccttgcat
    77581 caatgcaccg ctcaatgcaa aacaactccc tacaagaaat gctcccgcca cacgaggcaa
    77641 acgaatattt cgtatgattt ggtgactttg ttttgatcta tcaaaatcaa acaacgcctg
    77701 ccaaaaatct gctttttcca cagtcgctgc gccatttgaa agagcaacaa aaaaaataat
    77761 caaaagaaca aaacagacca aaagcaggag tctatttttc ttcatagtcc tcataattga
    77821 tcctcctgct cttttggcaa caaatcatag gttagaaaaa ctggtttatt tgttcttgga
    77881 agcgtgacaa tcgttgcatc aatctcaaat atttttttca tacactcttt tgtgatcact
    77941 tcttcaggtg taccttctgt gatcaactta ccgtttttca ttgctaataa ataatctgaa
    78001 aaacgtgaag catgattaat gtcatgaatc gacatcaaga tcgttgtttg tttcatttga
    78061 ttgatttcag tcaataactg taggatctct aattggtgtg ccggatctaa aaatgttgtc
    78121 ggttcatcca agatcaagat atctgtttcc tgagcaagcg ccatagcgat ccagacacgc
    78181 tgggtttgtc caccagacag cgttgcgata tcccgcatac gaaatccagc tagacctgta
    78241 gcatccaacg cccactcaat tgcttcatga tcttgcgtgt ccatgccact gaacagtttt
    78301 tgataagggt atcgtccgta agatactact tcttctactg tcatacctgt agggtgttca
    78361 ctagtttgtg ctaataatgc aatttttttt gcaagttctt ttgaactgta tgtagagata
    78421 tcagagttat tgacaatgat ctttcctgat ttcacaggta gtatacgggt aaaacttttc
    78481 aataaagtag attttccact tccatttggc ccaatcaaac tagtgatttt cccttcagga
    78541 atcgtaacag acatgttttc aatgattttt ttgttttcgt agccggctgc aatgtcagct
    78601 gctcttaatc tcgtcatttc acccatcctt tcgctgaaaa tcattctcaa ttatgacgct
    78661 gtttcaacat ttcgtcaagc gctactttca tatctatagc caaatgaagc ggttgacagc
    78721 gttcgaaata tcaggaataa taaccaatga gaaagattct caattatgtt aggaggaaag
    78781 aaatgaaatt aaaaacaaaa gtattcacat tatctagcat attgctgctg gctggagtac
    78841 tgagcgcttg ctccccctct tcagataaag aaacagctac aactgccaat tcgacgactt
    78901 catccaatag tactcataca gtcacagata cacttggaca taaagtagag attccaaacg
    78961 cgcccaaacg gatcatcggc agttacttag aagactatct gattgcacta ggggaaaaac
    79021 ctatcgccca gtggactgtt ggcagtggtt ccattcaaga ttatctgcaa gatgatttaa
    79081 aggatgtccc aacgatttct tatgaccttc cttatgagaa agtgttaagc tttgagcctg
    79141 atttgctgtt gatttcttct tccgctactg tcgaaggcgg gaaatacgaa caatatagca
    79201 aaatcgcgcc aacttatgtt gtaaaaaacg gaacagatgt cacatgggaa gaacaactaa
    79261 aagatgtcgg caaagctttg gcaaaagaaa aagaggcaga aaaaatcatt tccgattatc
    79321 aaaaatccat caagaaaact cgagaagaac tagcagataa aatcgagaac aagacagctg
    79381 cagtgttgtg ggtgaccaac aactcagcct ttatggtcag caaaaatcgg tcaagtggaa
    79441 gaatcgtata cgacgatctg gaatttggtg ttcctgatct agtggaagag gtctccaaaa
    79501 aagccacttc tgactggtct gctgtttcct ctgaaaagct agctgaatta gatgctgact
    79561 acatcatcct tgtgaacagt gacaaagatg ctgccatgtt caatgaacca agctggaaga
    79621 atctaaaagc agtgacagac aatcatgtac tgcaattcgg acctgaatct agttggctat
    79681 ataacggacc tattgccagt caggaaatgg tcaatgatat caaagaaaaa ctaaattgat
    79741 tttaactaaa aaaagcatct tcacgattag tcgtgagatg ctttttttct tattaacaaa
    79801 ctagacgcat agattttatt cttcttttga agcaacccta ttttttactc tttcccattt
    79861 ttgaaaacga tgggcatata gattttcttg atccgttatc ccctcatact cctctataag
    79921 ggcgaagtct gaaaaatcaa tattcccaat atacgtatcg ccttcaaacg tgctatcgat
    79981 caatgttcgc cagatccgac cagtgtaagg aagaagttct tgaaaaatcc gactaccacc
    80041 cgaaacatag atatcttctg agatcgtttg actatacgac aaaagttcat cgatcgaatg
    80101 cattacttcc gcattttctt tcgtgcgaaa atttggttgc gttgtcaaca cgatgatatg
    80161 gcgataagga agtgaaagat cccccattcc ttcataggtc tttcttccca tcactaaaat
    80221 tcgatccatt gtatgttcgc gaaagaaacg catatcattt ggcaatcgcc atggtaacaa
    80281 accatttttg ccgatcagac catttttatc ttgtgcccac atggaaataa acatattatc
    80341 cgctccttat gattttagat gttttgagat aaaaaaagtc tcaattcttt gaccagcaag
    80401 gaattgagaa ctttaaaaac attattttgt ttcacggtgc aaagtaactt tgcgttcgcg
    80461 tgggcaatat ttttgttttt ccaaacgatc aggattgtta cgtttgtttt tgcttgttag
    80521 atagttacgt tctttacaag aagtacactc taaagtgatg tttacgcgca tgtttttccc
    80581 tcccattttt acaagaatcc tctaagatga ctctcagact tgattatctt accatgattt
    80641 tttctagatt gctagtgttt ttcacgattt tgttaagtaa aactacttga cgataaatac
    80701 aacggtttta cttctcaaac aaaatctttt tctttttgta taaataccct tacacttgtt
    80761 tatatagatt atgtttttta ataaaggggg atactaatat gccatggaac atgaaggact
    80821 ttcctgcatc aatgaaaaac ttagataaat tgacaagaaa aaaagcaatc gacatcgcaa
    80881 atgcattatt agatgaaggg taccctgata accgtgcgat cccaattgcc attgatcaag
    80941 caaaaaaatg gtatgaagat gctagtgaat cagaaaaacg aactttcgaa aaagaaaaaa
    81001 atccaagcaa gacggatgaa cacgatacga atcctcgtgc tggaaaactg cttgattcag
    81061 atgtgatcgt agaatatgag gaagaacaat ggatcgtgaa atctaaaggg gcaaaaaagg
    81121 caagcaacca ttttgataca aaaaaagaag caatcgaaaa aggaaagcaa gtagcacaaa
    81181 acaaagaatc aactttgttc atttataaaa aagatgggac aaaagaaaaa gaaatcgatt
    81241 attgaacata tgtaaagggg ttgtgacgaa aatcgtgtca caaccccctt atgttcgaaa
    81301 caatggtgtt cctctgccaa ctccgaacca taagtcataa tatctataaa acgggaagag
    81361 ctgttttttg aaattgtttc ttatcactca gtgttaaacg gtaggagaaa acctcttttt
    81421 tattgatatt tgattttcat caaacagtca catagtcgat tgcttctgct tgcggaatcg
    81481 tttcatctac aaagtagact ttataccatg tcaagaaact gaagattgtc cagatttttc
    81541 tttgctcttc tttacgtcct tcgtgatggt catctagcaa cttcatgatt ttttcttgat
    81601 caaaaaattc ttttgcaaaa tctgcttcga ataatgcttt gacttgttcg tagccgtgtt
    81661 cttctttcaa ccaagctttg attggcacag ggaatcctaa tttcacacga ttcgaccatt
    81721 cttccggaag atgtttgttc gcagcttgtc tgaaaatatc ttttgtgttg ttttgattca
    81781 ataaaaactt acttggtatt tgttgagcca atttcatgac ttcgatatcc aataaaggta
    81841 ctcggacttc caaagaactt gccatagaaa gtttatctgc ctttaacaag atatcttttg
    81901 gcatccattg atgaagatcg acatattgca tcttattgac ttcatctttg attccttctg
    81961 ttttctcgta atgaacagtc atgatttcat ccacagatgg tgctgtttga tattttggtg
    82021 ttaacacttc tgatgcttct gattcttcga acactcgagc atgaccgata aaatattctt
    82081 ttgcaggagc aagtgattca tataaatgga tccgtccatg gaagtttttc atttttccga
    82141 ttttacgtcc taaattatag cgtgttcctt ttggtaattt tttcaatcct tgagcaatca
    82201 cacggatgaa ttttgaattc gtatggaatc catacgtttg gtatcccgca aacagttcat
    82261 ccgccccttc tccagattgg actacccgca cactttgtga agcaagattt gctaaaaagt
    82321 acaaaggtac gcaagaagga tttgaatcag gttcatctaa gtgatactgg atcaaaggga
    82381 atgctttgaa cgacatgtct ccgtcgatca ctgctgctgt attatctaag tccaatagtt
    82441 cggttagttt tctggcttca atcgcttcat tataggtttt atcatcaaac ccgattgaga
    82501 aagaatgatc tggtttcaat acagaggtta cataactgga atcaaccccg ctggataaga
    82561 aagaaccaac ttctacatca ctgaccgtat gtgcttcaat agaagcttga acggtttcgt
    82621 cgattttttc gatccattct tgtcgggaat gcgtttcttt tgtttcaaaa tctgcatccc
    82681 aatattgctg aatgtctatt tttccatctt tatacgtata ataatggcct tcaggcaaac
    82741 gatagacatc tttgaagaat gtttcgccgt ttaatggaga atattggaaa gtcatataag
    82801 gtttcaacgc ttctttgttc aattctttgt taaaatcagg atgaggcaga aaacttttga
    82861 tttctgaacc aaacataaat gttccgttca tttctgcata ataatatggt ttgatcccaa
    82921 agtggtctct tgcaccgaat aactcattct tttcattatc ccaaatagca aaagcaaaca
    82981 ttccgcggat cttttgcaat aattctgttc cccattcttc gtaaccatgc aaaaggactt
    83041 ctgtatctgc atgtgtttga aaaacgtggc cagctgcaat caattcttct ctcaaaggct
    83101 ggtaattata gatttcgcca ttaaaaataa tgatctttgt ccgatcttca ttgtaaatag
    83161 gctgagtacc gccctctaag tcaataatac ttaatcttct gaatcctaaa gcaacatgtt
    83221 tatcgatata ttctcctgaa ctattaggtc cacggtgaac gattcgatcc atcattgtat
    83281 taataattgt ttttttgttg tccttgtcgt taacaaaacc tacaataccg cacatttaac
    83341 tttcacatcc taatataaaa ttactgttta tttcattcat atgcatctta tcatagaata
    83401 aatagcggac gaatattttc tctcttacaa tttcgtcacg tgaaaacaaa agatgaaagt
    83461 ttctgttttt acagaaaata aagtcccaat atctaattta ccatgttttc ttttttgagg
    83521 ctaccttatt ctcttcgtgt taaaaaaata ttagtggatg ctatttccaa aaaaaccagc
    83581 aaaaaaagac acgacctaaa gatcgtgtc
//
LOCUS       DADGHT010000002        64414 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.002, whole genome shotgun sequence.
ACCESSION   DADGHT010000002 DADGHT010000000
VERSION     DADGHT010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 64414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64414
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.002"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(132..509)
                     /locus_tag="JX887_000079"
     CDS             complement(132..509)
                     /locus_tag="JX887_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256101.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            765..1493
                     /locus_tag="JX887_000080"
     CDS             765..1493
                     /locus_tag="JX887_000080"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAX1256102.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1493..1747
                     /gene="purS"
                     /locus_tag="JX887_000081"
     CDS             1493..1747
                     /gene="purS"
                     /locus_tag="JX887_000081"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAX1256103.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1749..2420
                     /gene="purQ"
                     /locus_tag="JX887_000082"
     CDS             1749..2420
                     /gene="purQ"
                     /locus_tag="JX887_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAX1256104.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2421..4643
                     /gene="purL"
                     /locus_tag="JX887_000083"
     CDS             2421..4643
                     /gene="purL"
                     /locus_tag="JX887_000083"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAX1256105.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4628..6067
                     /locus_tag="JX887_000084"
     CDS             4628..6067
                     /locus_tag="JX887_000084"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAX1256106.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6099..7142
                     /locus_tag="JX887_000085"
     CDS             6099..7142
                     /locus_tag="JX887_000085"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAX1256107.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            7139..7717
                     /gene="purN"
                     /locus_tag="JX887_000086"
     CDS             7139..7717
                     /gene="purN"
                     /locus_tag="JX887_000086"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAX1256108.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7714..9249
                     /gene="purH"
                     /locus_tag="JX887_000087"
     CDS             7714..9249
                     /gene="purH"
                     /locus_tag="JX887_000087"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAX1256109.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9265..10539
                     /gene="purD"
                     /locus_tag="JX887_000088"
     CDS             9265..10539
                     /gene="purD"
                     /locus_tag="JX887_000088"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAX1256110.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10661..11575
                     /locus_tag="JX887_000089"
     CDS             10661..11575
                     /locus_tag="JX887_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAX1256111.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11708..13273)
                     /locus_tag="JX887_000090"
     CDS             complement(11708..13273)
                     /locus_tag="JX887_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAX1256112.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13266..14717)
                     /locus_tag="JX887_000091"
     CDS             complement(13266..14717)
                     /locus_tag="JX887_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1256113.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14731..15747)
                     /locus_tag="JX887_000092"
     CDS             complement(14731..15747)
                     /locus_tag="JX887_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1256114.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15967..17055
                     /locus_tag="JX887_000093"
     CDS             15967..17055
                     /locus_tag="JX887_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAX1256115.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17109..18635
                     /locus_tag="JX887_000094"
     CDS             17109..18635
                     /locus_tag="JX887_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAX1256116.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18637..19842
                     /locus_tag="JX887_000095"
     CDS             18637..19842
                     /locus_tag="JX887_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1256117.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20099..21076
                     /gene="guaC"
                     /locus_tag="JX887_000096"
     CDS             20099..21076
                     /gene="guaC"
                     /locus_tag="JX887_000096"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAX1256118.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21340..22764
                     /locus_tag="JX887_000097"
     CDS             21340..22764
                     /locus_tag="JX887_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAX1256119.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23225..24334
                     /gene="pdhA"
                     /locus_tag="JX887_000098"
     CDS             23225..24334
                     /gene="pdhA"
                     /locus_tag="JX887_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAX1256120.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24337..25314
                     /locus_tag="JX887_000099"
     CDS             24337..25314
                     /locus_tag="JX887_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAX1256121.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25339..26982
                     /locus_tag="JX887_000100"
     CDS             25339..26982
                     /locus_tag="JX887_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HAX1256122.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26990..28396
                     /gene="lpdA"
                     /locus_tag="JX887_000101"
     CDS             26990..28396
                     /gene="lpdA"
                     /locus_tag="JX887_000101"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAX1256123.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28558..28833
                     /locus_tag="JX887_000102"
     CDS             28558..28833
                     /locus_tag="JX887_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAX1256124.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28839..29606
                     /locus_tag="JX887_000103"
     CDS             28839..29606
                     /locus_tag="JX887_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAX1256125.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29774..31603
                     /gene="typA"
                     /locus_tag="JX887_000104"
     CDS             29774..31603
                     /gene="typA"
                     /locus_tag="JX887_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAX1256126.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31864..33623
                     /gene="recQ"
                     /locus_tag="JX887_000105"
                     /pseudo
     CDS             31864..33623
                     /gene="recQ"
                     /locus_tag="JX887_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
     gene            33737..34039
                     /locus_tag="JX887_000106"
     CDS             33737..34039
                     /locus_tag="JX887_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAX1256127.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34042..35205
                     /locus_tag="JX887_000107"
     CDS             34042..35205
                     /locus_tag="JX887_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAX1256128.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35231..38659
                     /locus_tag="JX887_000108"
     CDS             35231..38659
                     /locus_tag="JX887_000108"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAX1256129.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38680..39804
                     /locus_tag="JX887_000109"
     CDS             38680..39804
                     /locus_tag="JX887_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256130.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39794..40231
                     /locus_tag="JX887_000110"
     CDS             39794..40231
                     /locus_tag="JX887_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAX1256131.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40215..40553
                     /locus_tag="JX887_000111"
     CDS             40215..40553
                     /locus_tag="JX887_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAX1256132.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40672..41232
                     /gene="rsmD"
                     /locus_tag="JX887_000112"
     CDS             40672..41232
                     /gene="rsmD"
                     /locus_tag="JX887_000112"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAX1256133.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41229..41720
                     /gene="coaD"
                     /locus_tag="JX887_000113"
     CDS             41229..41720
                     /gene="coaD"
                     /locus_tag="JX887_000113"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAX1256134.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41710..42753
                     /locus_tag="JX887_000114"
     CDS             41710..42753
                     /locus_tag="JX887_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAX1256135.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            42912..43640
                     /locus_tag="JX887_000115"
     CDS             42912..43640
                     /locus_tag="JX887_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAX1256136.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            43756..44001
                     /locus_tag="JX887_000116"
     CDS             43756..44001
                     /locus_tag="JX887_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAX1256137.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            43998..44216
                     /locus_tag="JX887_000117"
     CDS             43998..44216
                     /locus_tag="JX887_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAX1256138.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            44352..44891
                     /locus_tag="JX887_000118"
     CDS             44352..44891
                     /locus_tag="JX887_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAX1256139.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            44884..47157
                     /locus_tag="JX887_000119"
     CDS             44884..47157
                     /locus_tag="JX887_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAX1256140.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            47195..48241
                     /gene="holA"
                     /locus_tag="JX887_000120"
     CDS             47195..48241
                     /gene="holA"
                     /locus_tag="JX887_000120"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAX1256141.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(48330..48584)
                     /locus_tag="JX887_000121"
     CDS             complement(48330..48584)
                     /locus_tag="JX887_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAX1256142.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(48984..49253)
                     /locus_tag="JX887_000122"
     CDS             complement(48984..49253)
                     /locus_tag="JX887_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256143.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(49723..50178)
                     /locus_tag="JX887_000123"
     CDS             complement(49723..50178)
                     /locus_tag="JX887_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAX1256144.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(50316..52244)
                     /locus_tag="JX887_000124"
     CDS             complement(50316..52244)
                     /locus_tag="JX887_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAX1256145.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(52441..53274)
                     /locus_tag="JX887_000125"
     CDS             complement(52441..53274)
                     /locus_tag="JX887_000125"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAX1256146.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(53466..54170)
                     /locus_tag="JX887_000126"
     CDS             complement(53466..54170)
                     /locus_tag="JX887_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAX1256147.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(54193..54819)
                     /locus_tag="JX887_000127"
     CDS             complement(54193..54819)
                     /locus_tag="JX887_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAX1256148.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            55145..57520
                     /locus_tag="JX887_000128"
     CDS             55145..57520
                     /locus_tag="JX887_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAX1256149.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(57544..58035)
                     /locus_tag="JX887_000129"
     CDS             complement(57544..58035)
                     /locus_tag="JX887_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAX1256150.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            58222..59142
                     /locus_tag="JX887_000130"
     CDS             58222..59142
                     /locus_tag="JX887_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAX1256151.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            59296..59640
                     /locus_tag="JX887_000131"
     CDS             59296..59640
                     /locus_tag="JX887_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAX1256152.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(59830..60330)
                     /locus_tag="JX887_000132"
     CDS             complement(59830..60330)
                     /locus_tag="JX887_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1256153.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            60858..60941
                     /locus_tag="JX887_000133"
     tRNA            60858..60941
                     /locus_tag="JX887_000133"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60892..60894,aa:Leu,seq:cag)
     gene            complement(61265..61903)
                     /locus_tag="JX887_000134"
     CDS             complement(61265..61903)
                     /locus_tag="JX887_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAX1256154.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            62238..62672
                     /locus_tag="JX887_000135"
     CDS             62238..62672
                     /locus_tag="JX887_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAX1256155.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            62695..63015
                     /locus_tag="JX887_000136"
     CDS             62695..63015
                     /locus_tag="JX887_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256156.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            63156..63347
                     /locus_tag="JX887_000137"
     CDS             63156..63347
                     /locus_tag="JX887_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256157.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(63418..63675)
                     /locus_tag="JX887_000138"
     CDS             complement(63418..63675)
                     /locus_tag="JX887_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAX1256158.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            63833..64096
                     /locus_tag="JX887_000139"
     CDS             63833..64096
                     /locus_tag="JX887_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256159.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            64120..64308
                     /locus_tag="JX887_000140"
     CDS             64120..64308
                     /locus_tag="JX887_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256160.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
BASE COUNT        21273 a        11046 c        13771 g        18324 t
ORIGIN      
        1 caaaaaagaa gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc
       61 aataatagga acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa
      121 aaatagagga attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga
      181 tgttgcagca agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg
      241 atacgataat gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct
      301 ttgtgttctg tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct
      361 cggcggattt ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg
      421 atcgacagca aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa
      481 agctgacctt gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa
      541 atttttagtt aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta
      601 taagattttc gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca
      661 tatttttgtt gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa
      721 aacgatgtat ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac
      781 ttttgtatga aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga
      841 tagaatattt agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa
      901 aaggagaatt gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa
      961 taaaaaatca ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa
     1021 ttatccctct ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag
     1081 gtgttcccga aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc
     1141 agttggatga tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg
     1201 aagaaatcag tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat
     1261 ttgctaaggt cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac
     1321 aaattttgct tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga
     1381 atgaacatat ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc
     1441 aagaagtata taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt
     1501 cgtaaaagta tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa
     1561 aaaagcagtc catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt
     1621 tgagatacaa cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga
     1681 caagctgctt gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga
     1741 agtataacat gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt
     1801 tatgggcagt tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct
     1861 ctttagaagg atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga
     1921 gatgcggtgc gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag
     1981 aagggaaacc agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt
     2041 tgccaggtgt actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga
     2101 aagtcaaccc caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc
     2161 cagttgctca tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa
     2221 aaaataatca gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg
     2281 cagggattac gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag
     2341 tagaagactt gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact
     2401 tcggaaaggt gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga
     2461 aaaaaagaat ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag
     2521 atatcttagg aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg
     2581 aacattgttc ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc
     2641 atgtgttgca aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag
     2701 ttgtcttcaa agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg
     2761 cgacaggagt tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt
     2821 tgctagattc attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag
     2881 aagtagttgc aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg
     2941 aaattgcatt tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt
     3001 tgattgaaca caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt
     3061 atgtaggtgc aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat
     3121 ttaatcaaga agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa
     3181 agctgctgct tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta
     3241 tacaggatat gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg
     3301 gctcaggact tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt
     3361 atgaaatgat gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg
     3421 aagaaaaaat ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag
     3481 taacagacga cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag
     3541 tcgatgcatt agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa
     3601 tcgtagaatt tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat
     3661 tgcttgatct gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg
     3721 attcacaagt acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg
     3781 ttagagggac gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt
     3841 tggatccaaa aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta
     3901 gcggtggtaa gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag
     3961 aagttttttg ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag
     4021 gaactcctgt tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct
     4081 atccaacacc aatgattggt atggtcggat tgattgagga tcataaacat atcactactc
     4141 aggaattcaa aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg
     4201 atggcagtga attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg
     4261 atctatccat tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga
     4321 ttgaaagtgc tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt
     4381 tcaaacatca gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag
     4441 aaactcaatc aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa
     4501 tgatgggaga tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt
     4561 cagcaactga cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg
     4621 caatcgtatg tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg
     4681 gggtcatcca gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg
     4741 acaagaaggt gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt
     4801 ggggctgctt tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc
     4861 tgcaatcgga catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc
     4921 ttttctattc aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa
     4981 tgctcgttcc cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga
     5041 tacggagata ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt
     5101 aaaaagtgct ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc
     5161 aatgattgcc gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa
     5221 cggagcatac gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat
     5281 aagagatgtc cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg
     5341 ctttacgaag gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc
     5401 agattcaaac atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt
     5461 agcgaaagaa tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc
     5521 agccgcaagc ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa
     5581 tcaatacatt gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg
     5641 aatgaaatta tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga
     5701 ttcaattgtt cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc
     5761 aaaagaagtc catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat
     5821 tgatattcaa acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga
     5881 atgtatcggt gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg
     5941 tctggaaaaa gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc
     6001 gacgccgtta tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt
     6061 cttttaaaag cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag
     6121 ctggcgtaga tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa
     6181 aaacggaacg tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat
     6241 cggtctttca attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat
     6301 tagcagtggc aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt
     6361 gtgtcaatga tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa
     6421 cggggaaaaa tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg
     6481 ttcaaggaaa tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag
     6541 gtaatgatta tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga
     6601 caggagaaac gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt
     6661 caaatgggta ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat
     6721 caaaactgcc agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct
     6781 atgtttcttc cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca
     6841 ctggtggagg gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa
     6901 tcaaacttgg ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa
     6961 ttcctgagat ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc
     7021 aagaatcgaa agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg
     7081 aaatcgggaa agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat
     7141 gagaatcgct gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct
     7201 atcgaaaaaa ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata
     7261 tgttttgaaa cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt
     7321 tgattcaaaa aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga
     7381 tttgatcgta ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga
     7441 taaaagaatc atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat
     7501 acgtgatgcc tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca
     7561 aggtgtagat actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac
     7621 gttcgattct ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat
     7681 tagtgaaatt attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca
     7741 gataaaactg ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt
     7801 tcaacaggag gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa
     7861 gaagtgacag ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc
     7921 catggtggtc ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa
     7981 aatatccaac caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg
     8041 aaaccagatg tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg
     8101 ctccgtagtg cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat
     8161 gaagaagtac tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa
     8221 ctagcggcaa aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta
     8281 acggattggg tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa
     8341 acgcttcgtt acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg
     8401 gaaaaatatt cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat
     8461 atccgagatg cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc
     8521 gccttgaaac acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg
     8581 gaagcagcgt atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga
     8641 gaagtagatc tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc
     8701 ccttcttata cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg
     8761 acagtagact ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt
     8821 ggacttcttg tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg
     8881 acaaaacgta agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc
     8941 aaacatgtga aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga
     9001 gccgggcaga tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa
     9061 atggaaggtg cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat
     9121 gcagccaaac atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat
     9181 tctattgata tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt
     9241 agacattaga gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa
     9301 catgcaataa gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca
     9361 ggaaatccgg ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat
     9421 tcagcgttaa tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa
     9481 gttcctttgt taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt
     9541 ccgacaaaag cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat
     9601 acttatcaaa tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg
     9661 tatatcaaag aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa
     9721 ggtgtagtcg tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac
     9781 cagcatcgat ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa
     9841 gaattctccc ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa
     9901 gatcataagc gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat
     9961 tcaccagtac cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa
    10021 ccagcggctt tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt
    10081 ttgattgcta cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct
    10141 gaaacgcaag tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta
    10201 ttagagaatc gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg
    10261 gttgcagctg ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg
    10321 gaagaagagc tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga
    10381 gcaggaggac gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa
    10441 aaaatttaca ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt
    10501 ggagaaaaag ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa
    10561 aaaatacaac aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt
    10621 ggtacacttt tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg
    10681 tacttctgat cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga
    10741 agatccagta aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc
    10801 agatatttat ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc
    10861 aatcaaacga gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt
    10921 tgatttttct aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat
    10981 ggattatgtg gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt
    11041 agctgaagcg tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa
    11101 tcaaaaacca atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa
    11161 tcagctgcaa tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat
    11221 gacagatgaa gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga
    11281 tatgacgatc caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg
    11341 gaacgaaaaa ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac
    11401 gacaccaact ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat
    11461 cgccggtacg atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat
    11521 gtctcgggaa gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt
    11581 gtcataagca ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt
    11641 cagcttcgag atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt
    11701 tcgtttatta gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa
    11761 tcccttgttt tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa
    11821 aagcaatatc tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc
    11881 tttgttctgt cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga
    11941 aatgagaggg acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg
    12001 taaaattttc tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg
    12061 aaggctgtga gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa
    12121 gcgagtcgtc ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt
    12181 gcgggatttt cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac
    12241 gatataatcg tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag
    12301 atacttcgtt tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat
    12361 caactggaag tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg
    12421 aactggcggt ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc
    12481 tttctgcgac aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat
    12541 ggaccaacgt ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa
    12601 ctattaaaaa tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc
    12661 taaataaaaa cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt
    12721 ggtttgctgc taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag
    12781 caagtttcaa tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat
    12841 tttttttcaa ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta
    12901 aagcagttac tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca
    12961 gataatcatc tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac
    13021 taataaatat gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc
    13081 cgtccatgaa aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg
    13141 aagacagtgc catctcacca tctccagctt cgccgacata agtgattgga taataagaac
    13201 caaggacagt tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa
    13261 aaactttata catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg
    13321 acagttgttc cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa
    13381 taaagaagga gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg
    13441 atccctttgg ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg
    13501 ttgtctataa ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat
    13561 cctttgtgac ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag
    13621 atcattttta aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc
    13681 atatggccgt atcttatttt taagatgact agataatcat tgatatggct aatttctttt
    13741 tcaagaggaa tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca
    13801 tgggtcatag tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc
    13861 aaactgttat aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt
    13921 gctaaatggt attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt
    13981 ttattcatgc tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag
    14041 ccaaggttcc ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg
    14101 acctttctct ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact
    14161 ccaagttcca ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt
    14221 gctaagtcga tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca
    14281 gaatctacct gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta
    14341 ttgatcagct cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac
    14401 gtactaattt ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt
    14461 tcttctagga tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc
    14521 cacatacttt ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata
    14581 tttgcgatcg tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc
    14641 aaagggataa cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg
    14701 cttaaatttt ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat
    14761 attctgctgg gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt
    14821 ttgaatattt ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt
    14881 acactcgact acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc
    14941 atcaatagtt acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc
    15001 taaagcaccg tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc
    15061 atttgtttct aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac
    15121 aattcggtga acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt
    15181 tggtttacga ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt
    15241 ctctgaacca gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt
    15301 gctgacaaat aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac
    15361 gaaaagctcg ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc
    15421 tcgctttgct tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat
    15481 catatccact ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat
    15541 gtagccattt cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc
    15601 agtatgcttt ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg
    15661 gtcaggtgct tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag
    15721 ggctaaaaaa aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta
    15781 tcttatcaga taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa
    15841 acttaaaaaa atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa
    15901 aaaatcaatg ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga
    15961 taaaaaatga aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc
    16021 attctattaa gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga
    16081 atcgctatgc cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg
    16141 gaattagaaa aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat
    16201 caagtagcac aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct
    16261 atcgatggtt cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg
    16321 atcgcctatg atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat
    16381 aattttggag taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa
    16441 ggaaaaggac cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta
    16501 atcaattaca acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc
    16561 gtgccatctg gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg
    16621 gcgcaagcaa ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct
    16681 gttttgtcgc catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg
    16741 tatgggagtg aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc
    16801 gttaaatcga tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta
    16861 gcaaaaaata cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat
    16921 gatactgaaa cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta
    16981 tctgtcgata aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc
    17041 gatctgaaaa attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga
    17101 taagaattat ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa
    17161 tccgagcgtt agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg
    17221 gagaaaacgg agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg
    17281 gctcctatga cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag
    17341 atagtgaaga aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt
    17401 caataaaaga gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg
    17461 aactgacaga aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga
    17521 atcttctagt atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat
    17581 tatcaaaatc cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag
    17641 aaagcgcgaa tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca
    17701 ttatttcaca taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg
    17761 atggacagac gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg
    17821 gaatggtggg cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag
    17881 tttattttaa agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa
    17941 acgaccacat caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg
    18001 gagcgggcag aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat
    18061 ccggacgtat attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg
    18121 caaacggact cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg
    18181 atattcggga aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag
    18241 ataaagaaaa agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa
    18301 actccatcca tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat
    18361 ccaagtggct gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag
    18421 atgttggggc aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag
    18481 ctgtctgtct tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata
    18541 cgatgaacga aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct
    18601 tgatgaaatt aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg
    18661 gataaaaaag agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac
    18721 agcatggtga tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt
    18781 ttctggcgtc cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta
    18841 gctgcaggga tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg
    18901 atggcgtttg ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg
    18961 atgacagtta tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg
    19021 gtagcttatg cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt
    19081 ggactgacac aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa
    19141 aaaatgtcta cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca
    19201 ttgattttag gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat
    19261 cgtcggaaaa atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta
    19321 tttacagcag tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg
    19381 attattttga tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca
    19441 gtagcaggtc gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg
    19501 atcaaaacaa agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta
    19561 gctggattag ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg
    19621 gaactggatg caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga
    19681 acaatcatgg gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg
    19741 attttaggcg tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc
    19801 gttgtgctag acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca
    19861 gaaaaaagac tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca
    19921 ttgtttcgtt tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc
    19981 tttttgctct tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc
    20041 ttgattaaat taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat
    20101 gaaagtattt gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg
    20161 ttctgaatgt gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc
    20221 tgccaacatg cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta
    20281 tttctatatc atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa
    20341 aaagcgtgga ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat
    20401 agagaagttg gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg
    20461 acatgctaac tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt
    20521 tgtgattgcc ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc
    20581 agatgcaaca aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg
    20641 ctttgggact ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa
    20701 gccgatcatc gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt
    20761 tggtgcgaca atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga
    20821 aacaaaagtc gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca
    20881 aaaaggcgaa aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt
    20941 gaaagataca ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg
    21001 aagagatctg gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa
    21061 tggagacaca atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca
    21121 ttaagtaata agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt
    21181 attatcgcag atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt
    21241 tttgtcacag tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta
    21301 aaatcaaaag aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa
    21361 aaacaaggac cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga
    21421 aggatcaatc ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg
    21481 aatcgttcca ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc
    21541 aaacgtggca gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga
    21601 atcgattggc ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa
    21661 ataagagaag caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg
    21721 ccagatgagc ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg
    21781 gaagaaaaag aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat
    21841 ttggaaagta aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt
    21901 cagcaagcaa tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta
    21961 gagtcacctt ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt
    22021 gggataccga tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa
    22081 aataaattga aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg
    22141 agtcaaaaac gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt
    22201 gaagacgatg tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga
    22261 acgattgatc cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca
    22321 acgaaaatcg gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa
    22381 gaaatgatgg agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat
    22441 gaagcaattg atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg
    22501 ataagcgctt ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac
    22561 tatgcctgga ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta
    22621 gatatgggtc ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga
    22681 atcaattaca gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt
    22741 ctagaaaagt ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct
    22801 tggatttaaa tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact
    22861 aagaaaaaac cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa
    22921 caaaactgta taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa
    22981 aatagaaaaa atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat
    23041 gctgttaata tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt
    23101 gtatttctca taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt
    23161 tattcactgt ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg
    23221 acaaatggca aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc
    23281 agatttccca gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt
    23341 acctgattta tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt
    23401 attagaccaa cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac
    23461 tgctggacaa gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct
    23521 tcttccaggt tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc
    23581 ttttttatgg tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct
    23641 accaccacaa attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt
    23701 gaagaaacga aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca
    23761 aggtgatttt tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta
    23821 tatccaaaac aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac
    23881 acttgcacaa aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc
    23941 gcttgcagta tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc
    24001 agtcctaatc gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc
    24061 aacccgctac cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg
    24121 cttccgtaaa tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat
    24181 cgaagcaact aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca
    24241 aaaggtttca gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca
    24301 aattgcaatt tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa
    24361 gcaatcacag atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt
    24421 gaagatgttg ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc
    24481 ggagaagacc gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc
    24541 ggtcttgcgt tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc
    24601 gaagcaatgg acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact
    24661 agaaatctac ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg
    24721 cattcggata atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct
    24781 tccaaccctt atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt
    24841 gttttcctag aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct
    24901 tacgaagttc ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc
    24961 acatacggag caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat
    25021 atatctgttg aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt
    25081 caatccgtgg aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc
    25141 gttgccgcgc aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca
    25201 atcggacgag tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg
    25261 ttgccaaatg caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag
    25321 aagggacgaa acaaagtcat ggcttatcaa tttaaattgc cggatatcgg tgaaggaatc
    25381 gcagaaggtg aaatcgtcaa atggttcgtc aaaccaggag atacgatcaa tgaagatgat
    25441 acattactag aagttcaaaa tgacaaatca gtagaagaaa tcccgtcacc tgttacagga
    25501 acggttaaaa atgtgattgt tccagaaggt accgtagcaa atgttgggga tgtattagta
    25561 gaaatcgatg caccaggaca cgaagacaat gaaggggaca gtggtgtagc cgcagaatcc
    25621 caaactccag ctaaaccggc tgctgaaccc actgttgata cagaatcagc tggatcgtca
    25681 agcgaaggag tcttccaatt taagttaccg gatatcggtg aaggaatcgc agaaggtgaa
    25741 atcgtcaaat ggttcgtcaa accaggagat acgatcaatg aagatgatac attactagaa
    25801 gttcaaaatg acaaatcagt agaagaaatt ccgtcacctg tcacagggac agttaaaaac
    25861 gtgattgttc cagaaggcac tgtagcaaat gttggggatg tattagtaga aatcgatgct
    25921 cctggacaca atagtgcacc gtcaactagt gcgccatcag ctgaagcacc aaaagaaaaa
    25981 gtggaaacat caggttcagc aagtgtcgtt gaagctgccg atccaaataa acgtgtattg
    26041 gctatgccat ctgttcgtca atttgcccgt gaaaaagatg tagatatctc acaagtaact
    26101 gcaactggaa aaggtggcag agtaacaaaa gaggacatcg aaaacttctt ggcaggtggt
    26161 ccaagcagtg caccagcgaa atcagaagcg ccagaagcgg cagcaccgaa agaagcagct
    26221 cctgcagcag aaagcaaacc agctgcacca gcaaaaccat tcaagtccaa cttaggagac
    26281 ttggaagaac gtgtagcaat gacgccaaca cgtaaagcta tcgctaaagc aatggtcaac
    26341 agtaagcata cagctccaca cgtgacattg catgatgaag tagaagtgtc taaactatgg
    26401 gataatcgga aacgatttaa agaagttgct gctgcaaatg gtacgaaact tactttcttg
    26461 ccatatgtcg tgaaagcttt aacagcgact gttaagaaat acccagtatt gaatgcatct
    26521 atcgacgatg caaaccaaga aatcgtttat aaacattact acaatatcgg tattgcaact
    26581 gatacggatc acggactata tgtaccaaat gtgaaagatg cagaccgcaa aggaatgttt
    26641 gctattgcag acgaaatcaa tgagaaagca aaattagctc atgacggcaa actatctgca
    26701 gaagatatgc gcaatggaac aattacgatc agcaatatcg gatctgtagg tggcggttgg
    26761 tttacaccag tcatcaacta tccagaagta gctattttag gtgtaggaac gattgcacaa
    26821 caaccaatcg taaatgctga aggcgaaatc gttgtcggtc gtgtgatgaa actgtcatta
    26881 agtttcgatc accgtatcgt agatggagca actgcgcaac aagcaatgaa taatatcaaa
    26941 cgtcttttag ctgatccaga gctattaatg atggaaggat gataaacaaa tggtagttgg
    27001 agattttgct gtagaattag atacagttgt aattggtgcg ggacctggtg gctatgtagc
    27061 tgccatccgc gctgctgaaa tgggacaaaa agtagcaatc attgaaagag agtatattgg
    27121 cggtgtttgt ttgaatgtcg gctgtattcc ttcaaaagca ctgatagctg caggacacca
    27181 ttatcaagag tcactagatt ctgaaatgtt tggagtaact agtgaaaacg tcaaactaga
    27241 ttttgcaaaa acacaagaat ggaaagaaaa caaagttgtc catacgttga cttctggtgt
    27301 tggtttccta ttaaaaaaac ataaggttga aacaatcgaa ggagaagcgt tcttcgtaga
    27361 tgatcacaca ctacgcgtca ttcatccaga ttcagctcaa acttattcgt tcaataacgc
    27421 aatcatcgca acaggttccc gtccaatcga gattccagga tttaaattcg gaggacgtgt
    27481 gttagattct actggcggat tagcattgaa agaagtacct aagaaatttg tgatcatcgg
    27541 tggcggtgtg attggtgccg aattgggcgg agcgtacgca aacttaggag cagaagtaac
    27601 gattcttgaa ggctcaccac aaattttacc aacttacgaa aaagatctag taaaattagt
    27661 agaagatgat ttcaagaaaa aaggcgtaac agtcgtaacg aatgcaatgg cgaaagaagc
    27721 agtcgataac ggtgacagcg tgacagtgaa atatgcagtg gacgggaaag aagaatccgt
    27781 tactgctgat tatgtgatgg tcactgtagg tcgtcgtccg aatacagatg atatgggctt
    27841 agaacaagcg ggtgtcgaag taggagaacg aggattgatc acggtggata aacaaggacg
    27901 tacgaacgta cctaacatct atgccatcgg tgatatcgtt ccaggggcgg cattagcaca
    27961 caaagccagt tatgaagcaa aaatcgctgc tgaagcaatc tctggcaaaa aagtagctgt
    28021 agattataaa gcaatgccgg cagtagcctt cactgatcct gaattggctt ctgtaggtat
    28081 gacgatcaaa gaagcaaaag atgctggtat cgaagcaaaa gcatataaat tcccattttc
    28141 agggaacggt cgggcattat cgcttggtaa aacagaagga ttcatccgtc tagttacgac
    28201 gatcgaagat aacgtgctta ttggcgcgca aatcggtgga gtcggcgcaa gtgatatggt
    28261 ctctgaatta gctttagcaa tcgaatcagg aatgaatgct gaagatatcg ccttgacgat
    28321 tcatcctcat ccatctcttg gcgaaatcgt catggatgct tcggaattag cattaggttt
    28381 accaatccat atttgatttg aataatacag gcgaaacgca actgaaaaat cagttgcgtt
    28441 ttgtttttta gaattatcaa taatattatt atgtaaactt aaaaatatga caacttcttg
    28501 gtttattacc acttcctatg ctacactgaa gaggaatatg aaataggaga gttgaagatg
    28561 caagaatatc agtatccact tgatttagat tggacaacag acgaaatggt cattgtaatg
    28621 aagatgtggg aagatctgga acgtgcgaat gaaaaaggga taaacaatga agcttttttg
    28681 aagacttatc agcagtttaa aactgttgtc aaatccattg gtgaggaaaa acgattggga
    28741 cgggaatttg aaaaagcttc cggttattct ttatatcgta cagtgcagca agcaaaaaaa
    28801 aatccaaaca aaactttgag aatgaacggg tgagataaat ggaacagatg attgatcata
    28861 tcaagtcctg gcttgaagaa gctggtgaga aaatcaaatc ttctcaacaa acattaacaa
    28921 tctcgcaaaa atcaaatcga acggatctag taacaaatgt cgatcgaaac atccagaatt
    28981 ttctaatcga aaaaatccat tcctttgatc cagaggcgaa aatattggca gaagaagaag
    29041 ggtgtaatca attatcggat ctcgatggaa gagtctttat catcgatcct attgatggca
    29101 ccttgaattt tgtgattgaa ggggaaaatt tttgtattat gctcgctgtt tatgaatccg
    29161 gcgttggaaa gcttggtttc atttatgacg tgatgagaaa tgaacttttt tggggtggaa
    29221 aaggaatagg cgtgtataaa aatgatgagc cattgcctag accagcaaat aaatccttat
    29281 cggaaggctt acttggtgtg aatagttatc ttttcggtca taataaatat ggaatccgag
    29341 aaattgcgga aagcagcatg gggacacgta tgtacggatg cgctggtctt gaactagtgg
    29401 caatcttgaa aggaaaccac attgcttata tttcaaacct tagcccttgg gattatgcag
    29461 cgggaaatgt cttattggaa gagtttggta tggtaacaag cggtcttttt ggtactcctt
    29521 tgacatttga aaaaagggaa tactatttag cagggacttc ttgtgcatat gcagaaatcg
    29581 cagacctttt gaaaaaagaa ggctgaaaaa aaggtagaaa tcattcacaa aaatgataaa
    29641 aacgagcaaa agattaattt tctcgaaaaa atgaaaacat tttactatat ttcatgaaaa
    29701 aagtctgcta taattagcag tcgagtaaaa tttgccctgt cataaagaac caataaaaaa
    29761 ggagttagtt acattgaatt atagaaacga tatccgtaac gtcgcaatta ttgcccacgt
    29821 tgaccacgga aaaacaacat tagttgatga actattaaaa caatcagata cattagacgc
    29881 acatacgcaa ttgcaagaac gtgcgatgga ctcaaatgcg ctagaaaaag aacgtggtat
    29941 cacgatttta gccaaaaaca cagctgtaga ctataaaggt attcgcgtaa acatcatgga
    30001 tactccagga cacgcggact tcggtggcga agtagaacgg atcatgaaaa tggttgacgg
    30061 cgttgtgttg gtcgtagatg cgtatgaagg aacaatgcct caaacacgtt ttgtattgaa
    30121 aaaagcactg gaacaacata tcacaccaat cgttgtcgta aacaagattg acaaaccttc
    30181 tgctcgtcct gagcatgtcg tagatgaagt tcttgaacta ttcatcgaat taggagcaga
    30241 tgatgatcag ttagactttc ctgtgattta tgcatctgca ctaaatggta cgtcaagctt
    30301 gtcagatgat ccagcagatc aagaaccaac catggcacct atttttgata caattattga
    30361 aaaaatccct gctcctgtcg ataacagcga cgaaccatta caattccaag tttcattact
    30421 tgactacaac gattatgtag gtcgtatcgg aatcggacgt gtatttagag gaacaatcaa
    30481 agtaggagac caagtagcat taattaaatt agacggaaca gttaagaaat tccgtgtaac
    30541 gaaattattt ggtttctttg gactaaaacg tctagagatt caagaagcaa aagctggaga
    30601 cttgattgct gtctcaggta tggaagatat ctttgtcggt gaaacagtta ctcctgtgga
    30661 tcatcaagat gcgttaccta tccttcacat tgacgaacca acattgcaaa tgactttctt
    30721 agttaataat tcaccatttg ccggtcgaga aggtaaattc gtaaccgctc gtaagattga
    30781 agaacgtttg atggcagaac ttcaaacaga tgtatcctta cgagttgaac caacaaactc
    30841 tccagatgca tggacagttt ctggtcgtgg agaattgcat ttgtctatct tgattgaaaa
    30901 catgcgccgt gagggatacg aattgcaagt atctcgtcca gaagttattg aaaaagaaat
    30961 cgacggtgta aaatgcgaac cgtttgaacg cgtgcaaatc gatacaccag aagaatatat
    31021 gggtagtgtt atcgagtcct tgagcttacg taaaggtgaa atgcaagata tggtccatac
    31081 aggaaacgga caaatccgtt tgacattctt aacacctgcc cgcggtttga ttggttattc
    31141 aactgaattc ctttcaatga cacgtggtta cggaatcatg aaccatactt ttgaccaata
    31201 tctgccaatg cttcctggtc aaattggcgg acgtcaccaa ggggcgcttg tttcgatcga
    31261 tacaggaaaa gcaacgactt attctatcat gagtatcgaa gaacgcggta cagtcttcgt
    31321 agaaccaggt acagaagtat atgaaggaat gattatcggg gaaaacagcc gtgataatga
    31381 tttgactgtc aacatcacga aagcaaaaca aatgacaaac gtacggtctg ctactaaaga
    31441 ccaaacatct gtcatcaaaa aaccaaaaca attgacgttg gaagaatctt tggaattctt
    31501 gaatgatgat gaatattgcg aagtaacacc agaaagcatt cgcttgagaa aacaaatttt
    31561 agagaaaaat gctcgtgaaa aagcatctaa aaagaaaaaa taatctgtaa aaggatgaag
    31621 agagaaacca gcttgttata aaaaatagct ggtttctttt tttgtccaac tcttttctgt
    31681 ggagaagtca tctttgtcaa tggacataaa ttcagaaaat acgccgaaag acgtttaaaa
    31741 gacttttaaa aaacttattt ctagagagtt tttgtttcat aataagataa tgtttcacga
    31801 aaggagatca acttgtcctt cgaagaaaat cgaagtaaaa tggcaagaga aaggagcggg
    31861 aagatgaacg acttattaaa acaatacttt ggctatgatg agtttagacc tggtcaaaaa
    31921 gaaattatcc agaaagtcat tgatcaggaa aatgtattag gaatcatgcc taccggaagt
    31981 gggaaatcaa tctgttacca gcttccagct ttactattag atgggcttac tgtggttgtg
    32041 tcccctttaa tctctttgat gaaggatcag gtggacgcgg cgaatcaatt aggtataccc
    32101 gccactttta tcaatagctc gttagatggt tacgaaacag ctagacgctt ccaagaaatc
    32161 gatagacagc agtaccgttt actttatatc gctcctgaac gttttatcat gccggatttt
    32221 atccaagcaa tgaagcgatg gaacgtccgt atgatcgcta ttgacgaggc acattgtatc
    32281 tctcagtggg ggcatgattt ccgcccaagt tatttacaga tggcgaacca gctagatcaa
    32341 ctgccaaatc gtcctgtaat tgttgctttg acagctacag cgactgtgca agtagctgct
    32401 gacataaaaa gacttttaaa aattccagaa aacaaccata ttcagactgg ttttgaacga
    32461 gaaaatctac gatttcaagt aattaaagat caaaaaaaag aacaatatct aatcgaatat
    32521 ttaaagatca acaaaaatca atctggtatc atttatgcag caacgagaaa agaagtagac
    32581 cgtctctatc atttgcttaa aaaattcgat ttttccgtgg gtagatatca tggtggtcta
    32641 aatgagaatg agcgaacaga aatgcaagaa gcctttttat acgatcgctt gcagctgatt
    32701 gtagcgacaa atgcatttgg tatgggtata aataaaagca atgtccgttt tgttatccat
    32761 tatcaaattc ctggctctct agaagcatac tatcaggaag ctggtcgggc gggaagagat
    32821 ggtctttcca gtgaagccat cctgcttttc tctcctcaag atatccaagt atccagcagt
    32881 cccaaagaga agaagggcaa aagcaaaaag aatatgaaaa attaaaagcg atgacagaat
    32941 acgtgtatat tgagtcctgt cttcagcaat acatcctaaa ctattttggc gagacaagca
    33001 gtccgtgcaa ccgttgtggt aactgtttag atgacagaga aatagtagaa gtaacgacag
    33061 aagcacagat ggttctttct tgcttaaaac gtatgggtga gaactatggt aaacaaatgc
    33121 tgatgaaagt cttagcagga tcgaaagaac aaaagctgca agctttaggt tttggacatt
    33181 tatctaccta tggactgatg aaaaaccaat cgcaaaaaga aacgatgcag ttaattgaat
    33241 atttgatatc gaatggctat cttctgacca tcaatggtga gtatcctgtt ttgaaagtaa
    33301 cagaaagagg gatacaagta ttgaaaggac aagaatctgt ttatcgaaag gaacccaaga
    33361 aagtccagca gctatcggat gaagaaaccg atacactatt tgaagtgctg cgggaactgc
    33421 gaacggatct agcatcagaa gcaggcgttc ccccgtatgt cgtattttca gattccacat
    33481 tgaaagaaat gagccgaata cgtccatcaa gcagattgga gatgcttcag ataaaaggag
    33541 ttggccaaag caagcttgat aaatatggcg aagccttttt atctcggata aaaaatgcgg
    33601 actctaacgt tctggataag tagaaagaac gaatacgtaa aaatgaataa aaacaactgg
    33661 ttaaatctgt tttttttgct ccttatgaaa atcaaatatg ttataattaa ggaattagaa
    33721 tgggaggtaa gcacagatgg attctttgtc gaaaaaactt gcgatccaag tattaaatga
    33781 tgaagcagaa cggatcaaac gattaatccg aaatcaaaac aacagtctct gtatctcaca
    33841 atgcaaagcc ttcgaagaag tggtagatac acagatgtac ggcttttccc ggcaagtcgg
    33901 ttttgctgtc cgtataggag taatcggaaa gaacgagggc cagctgatgt taagtgagct
    33961 agaacgagaa ttgaatcagt tatatagtga ggtttaccaa gaaatttatg ataaaaaaga
    34021 agttggcaag gaggaataga cttgcctaag aaagtgaaaa aaaggcatct attagactat
    34081 agcatcttga ttccctattt aattttatgt gtattgggat tgatcatggt atatagttct
    34141 acgtcgtatc tattattaga aaacggacaa aatccgtccg catcagtcat taaccagagt
    34201 attttttggg tgcttagctt gattgctatc gcactacttt ataaaatgaa aacagatgtt
    34261 ttgaaaaacc agcgtttgat catggcagcc atcgcagttt tgacgatttt gctgctgatt
    34321 gttgtgtttt ttggtaagga gatcaatggg gcgaaaggtt ggctgcaaat tgcaggattc
    34381 tcgatccaac ctgccgaata cctaaaaatc atttctatct ggtacctgtc tctgacttta
    34441 tctaaaagac aaaacagtgt acaaaaagat tttcttggga ctgtgaaacg tccacttgca
    34501 atggttatcg gacttactgc attagtcgct attcttcccg attttggtaa tgcggcagtt
    34561 atctttttga ttattttggt tctgctttta gccagcggag tcaattatgt gtatactttg
    34621 attgtaggag taggaggctt ttgtctaagt acttttacga tctggctgat caatatcaca
    34681 aacggaaaga tcttacccgg acgtttacag tatatctata atcgatttgc tatttaccaa
    34741 aatcctttct cagacgaatt aaataaaggg catcaactag tcaacggcta ctatgccatg
    34801 ttcaacggag gactatttgg caggggatta ggtaacagta tccagaaaaa aggattttta
    34861 caagaagcac aaaccgattt tatttatgca atcgtagtgg aagaactggg agtgattatg
    34921 gggattttga tattagcgtt gctattcttt atgattgtgc gcattgtcct tgtaggtatc
    34981 cgttcaaaag atccgttcaa ttcgcttttg tgcattggga tcggcgcaat gtttttgatc
    35041 caagtatttg tcaatcttgg aggaattact ggcgttattc ctttgacagg gatcacgttc
    35101 ccatttttaa gtcaaggagg ctccagtttg ctgatgcttt cgatttgtgt cggctttgtc
    35161 ctcaacatca gtgcggatga aaaacgcaag agcttaggtt tataataaaa aaagatgtag
    35221 gagtggttcg atgaaaaaag ttttagttgc taacaggggt gaaatcgctg tacgtgtatt
    35281 tcgtgcttgt acagaattag gaattaaaac tgttggaatc tatgcagaag aagatgaata
    35341 ttccgtacac cgtttcaaag cggatgaagc atatttagta ggacaaggaa aaaaaccgat
    35401 tgatgcgtat ctagatattg aagggatcat ttctatcgcg aaagaatgcg gagctgacgc
    35461 tattcatccg ggttacggtc ttttgtcgga aaacttgaat tttgcgcaac ggtgcgaaga
    35521 agaaggcatc atttttgttg gacccaaact gcatcattta gatatttttg gagataaaat
    35581 caaagcaaaa gctgcagcta tcgaagcggg gattgcttcg attccaggca cagatggacc
    35641 aatcgcttct atagacgatg ccttggagtt tgcgaaacaa tacggttatc cgattatgat
    35701 caaggcagct ctaggcggcg gcggacgcgg catgcgtgta gctcacgatg aaaagagtgc
    35761 aagagagggc tacgaacgtg cgaaaagcga agcaaaagca gcctttggta gtgatgaagt
    35821 gtatgttgaa aaatacatcg ctaatcctaa gcatatcgaa gtacagattc tcggggatac
    35881 gcatggaaac gtcatccatc tttttgaaag agattgttct gttcagcgcc gtcaccaaaa
    35941 agtagtagaa gtagcgcctt gtgtctctat gaatgaacag caacgtcaaa aaatctgcca
    36001 ggcagctgtc caattgatga aatatgtcgg gtatgtcaac gcaggtacag tagaatttct
    36061 tgttgaagga gatgattttt actttatcga agtcaaccct cgcgtccaag tggaacatac
    36121 gatcacagaa atgattacag atattgatat cgtaacaacg caactgttga ttgctcaagg
    36181 tttggatctg cataaagaaa tcggattgcc tcagcaagaa ggaattaaat taaatggttc
    36241 agccattcaa tgccgaatca ctacagaaga cccgttgaat aactttttac cagacacagg
    36301 gaaaatcgat acgtatcgtt cacctggtgg ttttggcgta cgtctggatg tcggaaatgc
    36361 ttacgcgggc tatgtagtga caccgtattt tgattcattg ctagtaaaag tatgtacgca
    36421 tggtgctacc tttgaaacag ccattcagaa aatggaacgt tgcttgaaag aatttagaat
    36481 ccgtggagtg aaaacaaaca ttccatttat gctcaatgtc atcacacatc ctgaattcca
    36541 atcaggaaat gcaaaaacaa ccttcattga tagtacagca acattatttg aatttcctcg
    36601 actacgagac cgcggaaaca aaacgatgaa atatatcggt gaaattactg tgaatggttt
    36661 tccaggtatc gaaagtggcg aaaaaccatt ttatgaagaa ccacgtatgc ctaaagatct
    36721 aatcacaaga actgattacg taacggctaa gaatgtatta gatgcgaagg gtgccgatgc
    36781 tttggtcgaa tggatcaaag gacaggaaaa tttgttgttg acggatacga catttagaga
    36841 cgcccatcaa agtctgctag caactcgtgt tcggacaaag gatttcaagc agattgcacg
    36901 tttgactgga gaaggtcttc ctgaactctt ttcaagtgag atgtgggggg gagcaacatt
    36961 tgatgtggct taccgctttt tgaatgaaga tccttggcaa cggttgagaa aaattcgttc
    37021 tttaatgcct aatacgttgc tgcaaatgct tttcagaggt tcaaatgccg ttgggtattc
    37081 taattatcct gacaatgtat tggtggaatt tgtcaaagaa gcagcagcgc aaggaatcga
    37141 tgtatttcga atctttgata gtttgaactg gactccacaa atggaaaaaa gtatccaagc
    37201 tgtacgggat actggtaaaa tcgcagaggc agctatttgc tatactggcg atatcaacga
    37261 tccaagtcgg gcaaaataca atgttcagta ttataaagac atggcaaagg aactagaaca
    37321 actgggtgcg catatcattg caatcaaaga tatggctggg ctgcttaaac cgcaggcagc
    37381 ttatcgtttg attagtgaat tgaaagaaac gacagatctg ccaatccatc tgcatactca
    37441 tgataccagc gggaatggaa tcatcactta ttctgctgct tcaaaagcag gagtagacat
    37501 cgttgacgtg gcaatgagtg caatgagtgg gaatactagt cagcctagca tgagcagctt
    37561 gtattatgca ctggtcaatg gtccacggct gccagaaatc acgattgaaa atgcacagaa
    37621 attaaaccat tattgggaag atgtgcgcat gtattacaaa ccgtttgaaa acggcttgaa
    37681 tgctcctgaa acagaagtat atatgcatga aatgccagga ggacagtatt cgaatctaca
    37741 gcaacaggca aaagctgtcg gattaggtca tcgctgggat gaaatcaaac aaatgtatca
    37801 tactgtcaac ttgatgtttg gcgatatcgt taaagtaact ccatcatcta aagtagttgg
    37861 agatatggca ctatttatgg tccaaaatga tcttacagaa gaagatattt atgaaaaagg
    37921 cgaaacacta agtttccctg aatctgttgt gactttcttc caaggagaac tagggcaacc
    37981 cgttggcgga tttcctaaaa aattgcaaaa gattattctt aaaggcagac ctgcattgaa
    38041 tgaacgtcca ggtcttttgg ctgaatcagt cgacttcaac gaagtaaaaa aagaattggc
    38101 agaaaaaatt ggctatgaac caaaacaaga cgaagtatta agctatttga tgtatccgca
    38161 agtctttttg gactatcaaa aagcatataa tcaatttggc gatgttacat tactggacac
    38221 accaacattt ttccaaggta tacgtttggg tgaaacaatc aatgtacaaa tcgaacgcgg
    38281 aaaaacgctt atcattcgtt tagatgaaat cggagaaccc gatatcgaag ggaatcgcgt
    38341 actgttcttc aatttgaatg gacaaagacg tgaaatcact atcaaagata attcgatcat
    38401 cagtacggtc caaacccgat tgaaagctga accgacaaac cgagaacaaa ttggagcaac
    38461 gatgtctggt tctgttttgg atgtattagt gaaaaaaggc gataacgtta aaaaaggtga
    38521 tacgttgatg attactgaag cgatgaaaat ggaaacggcc atcgaagcac gttttgacgg
    38581 agaagtcgca catgtatatg tgtcttcagg agacactatt tcgtctggtg accttttgat
    38641 tgaagtgact gagaaataat aagcgaaagg tggggaaaca tgaaaagact gggtttgttt
    38701 tggctgattc tgctattagt tattgtggca ttctacatgg aaccagtctt gtttccgcca
    38761 aaacttgaag tgaaggaaaa ctctgatcaa caaatatcaa accaaatgac aacgtggaaa
    38821 taccaggagc ttaaagcaac tggtttttct acttatatcg gaaaaccgat cgatcagctg
    38881 gaaaaggatt ttggccaagc ctatgatcga ttaactagcg gatttggttt tgaaacaaga
    38941 tattatgaaa ataaagctag tcatctcaca tttgaagcga acatccaaga cagcagagtc
    39001 acaactgtta aagtactgca aacagggcct gctgatatcg cgccgtttta tttagggatg
    39061 acgatgcaag atcttacgaa aatcactact atctatacta atttcacttt tgagtaccat
    39121 gatacagaag ttggaatcga actaatggaa gaggatatga attatcgtcc gctaattgct
    39181 tttgataacg acacttttgc tattttattt tttgatcaaa caacaaacgg cctattttca
    39241 gttgtgtatt tagataaaga tagtcttttg aaactattgc catatcaagt gtttggtgaa
    39301 ggccttccac attatcaagc agataaatcg gctgattggg aatcaatcaa tcgcgttaaa
    39361 gaacgaaaaa gtacgacttt attaaatatg cttagaagag aagacgaact tcccatatac
    39421 aatcaaacac ttgcctttca aaaccacagt cagctgctac tacatgattt tttgacaagg
    39481 cctgaggaaa tattgtcaga ggaacgtatg gctgattggc aaaaatcgct aggcagtgct
    39541 caaacgacag tgaaattctc actgacgaat gatgaattgg agaagttaat cagtaaacaa
    39601 aaattagaaa atactagtgg gctatttatt catccggcga ttgacgctac tttttcgttt
    39661 ttatattggt acagcgatcc ttacaaccat gaccgtttca tggacccggg aacggattct
    39721 gtaggcattg ctttttctaa agaaaatatg ttagtcttat tgcaagaaga aaacggagaa
    39781 agtagtgata gcagtgatcg ttaacgaaga gctgtttcaa ctggaggatc aatgcctcca
    39841 agtcgctgaa atgataaaaa agagtaaaac gatggcttct tatcttgaac ataaacagtc
    39901 aatggaagaa tctgcaaaag tttgccagtt gaaagaagcg ttcttgtcta agaaagaagc
    39961 atttgaaaat gtagcggcat atggtgagta tgcacctgat tatcgtgaaa aaaaacgagc
    40021 tgttcgaaaa gcaaaaagac agcttgatat ggatgagcat gttgcagctt tccgatatag
    40081 tgaaacacag ctgcaaagtc tgttggatca aattgtccaa gtacttgccg aagaagtttc
    40141 taatgaaatc aaagtagatg caggtagccc gttttttgaa acgaaaaaac actttggatg
    40201 cggaggtaat tgtcatgcaa ttagacaata gtgaatttga aataacaaaa cgacgcgggc
    40261 tgatcgtatg ggtctacagc ttaaaacaat taaagaatct gaaaaagttc ggcttgttgc
    40321 attatgtctc aagaagaatg aaatatgtcg tgctttactt aaatgaagag acattggaag
    40381 aaacagaaga acgaatccgt aaattacatt ttgttcgaaa cgtagaacgt tcttaccgac
    40441 cggatatcga aatgaatttt gccgaaaaaa taggaaacaa aacagtatta aaagacgaag
    40501 gtttcgaaat tgaagagcta aatacagaaa tccgattagc tgaacatctt taaaaatctc
    40561 ttatgagcag tttttaaata aaaaataact tggataacga tcgatttttg atcattgtcc
    40621 aagtattttt ttggtatact agtaccagta ccatttctaa ggagtgagta gatgcggata
    40681 atatcaggaa attatggcgg gcgccgttta aaaagtttag caggggcgaa caccagacca
    40741 actacagata aagtaaaaga atccatattc aatatgattg gaccatattt tgatggagag
    40801 acagtattgg atctgtttgc aggaagcggt ggtttagcta tcgaagcagt atctagaggc
    40861 tgcagtcatg cggtatgcgt agacaaaaat taccaagcgc taaaaatcat caaagaaaac
    40921 atcgaaatta cgaaagaacc agagaaattt accacaataa aacttgatgc ggacaaagca
    40981 atcgaacggc tagcagcgga gaaacaacaa ttcgactact tgtttcttga tccgccatat
    41041 gcaaaacaaa aaataatcga tcaaatccat aaaatggaag aactgggact tttttctaaa
    41101 accgcagtta tcgtatgcga aacggataaa acagtcgaat tgccagaaac tgtggctgga
    41161 ttccatcaaa taagaaaaca gatttatggc ataacggccg taactatcta tagaaaagag
    41221 ggaaatcaat gaaacgtgca ttattcccag gaagttttga tccttttaca aaaggtcact
    41281 tagatacggt ggaacgtgcg gctaaattat tcgatgaggt agtaattggt gtttttatca
    41341 atacttcaaa gaaaagtttg tttcccccag aagaaagaat gacattgatc acaaaagctg
    41401 tttctcatct tcctaatgta aaagtcatgc atcaagaaaa tcaattgacg gtagaaacag
    41461 caaaagagat tggtgcagat gcgttgatca gaggcatacg aagtatcaaa gactttgaat
    41521 atgaacgaga gattgctcag atgaatcatc atctatatga tgaattggaa actgtcttct
    41581 tattagcaaa accagaatat agtcacgtga gttccagtat tttaaaagaa gtactgcact
    41641 ttggcggaga tgtgagcagc tacttaccgc cagtgatcaa cgaagcttta gctggaaagc
    41701 gtgaatcaaa tgaaagctaa acaatggttg aaaacagtac tgattatcat atttggaatg
    41761 ttgatcattg gatttgtagt agttcccttg ccgtattatg tagaatcacc gggagccacg
    41821 atcgatctga aagaactaat tacggtcaat gataaggaag ataaaggttc tgggtctttc
    41881 tctcttacct ctgttggtat caggcaagct acaggtttct tagctttaaa agctaaaatg
    41941 accccttttg aagaattgat cagtgaagaa gaattgactg gtggggcgac aaatgaagaa
    42001 tataatcaaa tgcaacagta ttatatggat tcttcccaaa atgcagcaat cgaacaagcg
    42061 ttaaaacttg cagacaagcc ttataaaatg gaattcaaag gcgtatatgt catgagtgta
    42121 gagaaaacat cgaatttctt tggcaagctt tcagttggag atacagtaac aaaagtagac
    42181 gggaaaagct ttcaaagtac agaagcattt atggattatg taaaaagcca aaaagttgga
    42241 caaacaatcg aaatcagtta tttgcataat ggtgaagaaa aaacagcttc tggtgatctg
    42301 atcgagttac caacagataa aaaggcagga ataggtatca cgcttactga ccataccgag
    42361 atcgaatcag atacagatgt tcgtattaat tctggctcta tcggtgggcc atcagcggga
    42421 ttgatgttca ctttagaaat ctatgaacaa gtcactggta aaaacttgcg acatggtaag
    42481 caaattgcag gaactggaac gatcaacagt gaaggagaag ttggccgaat cggaggaatc
    42541 gataaaaaag tggcaagtgc ggataaagct ggcgtagaga ttttctttgc accagatgat
    42601 acgatttcag acgatgttaa gaaagaatat cctgaaataa aaaccaacta cgaagaagca
    42661 aaagctgccg ctaaaaaatt gaattcctca atgaaaatcg taccagtaaa aacagtacaa
    42721 gaagcgcttg actatctaga gaaaatgaaa tgaaactaaa taattaaaga ggggttgtga
    42781 cacgagttct gtcacaaccc ctctttttcg tcaaaaatct tcacgataaa aataaaaaca
    42841 aaagaaaaaa ttgacgtaat tagatgttga agggacgatt ttgccagagc tcactgtttc
    42901 ttcaatttta aatgaaagga gtaatgaatg atttttactg gtcattcttt gaaaaaagaa
    42961 caatgataga aaaaatcagc aagaaaatac tagcttcacc caaattgatc atttggatgt
    43021 ctatgatagt tcttatcttt tgtatcgcaa gtggtttttt attatcaaat ttgctatttt
    43081 atagagaaac agaagagact gctgcaaaag aaatactttc ttcgtttagt tccagtggag
    43141 aagatccatc agctgaagga aacgatgtag aagaggatgc tcgtccaaag gtcatgtaca
    43201 ccgatatcaa aggaagtgtg aaggagcctg gtatctattc cttttcttca gaagaacggg
    43261 tctatgatgt actaaagcgt gcaggtggat tattagaaga agcggatagc gatcgaatca
    43321 acttttctgc gaagatagaa gatcagcaag tcctatatat ccctgctgta ggtgaagagc
    43381 tgccagaaca tcttgatcag ttggcatcct cggaaggaaa acagcctaca gcagattccg
    43441 agcctcccaa aataaatatc aatacagcca ctccatcaga acttcagcag attcctggga
    43501 tcggatcagt caaagcgcaa gaaatcattc gatttagaga agaaaacgga tccttccaga
    43561 aagtggaaga cctgcaggag atttctggta tcggtgaaaa gacagttgaa aaactaaaaa
    43621 acttcgttac aattaaatag aatgattcaa aatcgactgg cacgagcaat aaatggacgc
    43681 taatggatac taagaataat ccaattctaa gagcttggca ggacgaggag gtagtatttt
    43741 tggataggaa atagcttgat tgttcgcaaa gaaacattaa aaaaaccaat gctgaatgtc
    43801 tatctccaaa ataaaatatc tgggattcat attatgaata cggctgtcag cggcaataac
    43861 agtcaagctc tacgagaacg ctttgccaaa gatgtactta gctatacagc agataaagta
    43921 tttattctca ttgggacgaa tgatctagca gagcataaac aactttctaa agaaacgtac
    43981 caaaaaatct gcagtggatg atagttcagc tgaaaaaaga ctatagttct gatcatgctt
    44041 tctttatcac gccaccagca gtcgatgaga caaaacaaaa atatcggaat aacaagttga
    44101 tcaaagaata tatctctgtt ctcacagaag tagcaaaacg ccatgattgt gaagtatcga
    44161 tttttatacg gaatttcttg aacaaatgga ttcgaagaat ttttataatg ggctaatgga
    44221 tgacggactt catttcggca gtgaagggta ggatcttttg tcagacagga tgattcgtta
    44281 tatttaaaga atattttgtt taagcaatga gtacttttta atcaacttga aaaaacggag
    44341 gaatataaaa catgttagaa aaatcttcaa aagcatgcga tacgaataaa gaaaaagtta
    44401 ctgataagtc acataatgaa cgcattcctt gggaccagta ctttatggct caggcagtac
    44461 tgttatcttt acgtagtacg tgtacacgtt tagaagtagg agcgacactc gttcgagaaa
    44521 aaaggatcat tgctggcggc tataatggag cagtcagtgg agatgtccac tgcatagatg
    44581 aagggtgtta cgtcgtggat ggacactgct tgcgaacgat ccatgcagag atgaatgcac
    44641 tcctacagtg tgcaaaactt ggtatcccga cggaaggttc agaaatctat gtcacacatt
    44701 ttccatgttt ggcctgtaca aaggctttgt tgcaagctgg tgtgaaaggg atcaattatc
    44761 tccatgacta tcgaaatgat ccttatgccc aagcgttgat cgaacaatta ggtgtatctg
    44821 tacaccaagt tgctttagac tcacagcatt tttcaaaact tcaaaatgaa ttaacaggaa
    44881 aacatgtcta gcgttttaga aaggcatgtt cgaaatcggt tgatttttcc ggcaattacg
    44941 tcgatgatta tctgtttgtt gtattacact gacaattggg gttatcgttt gcttcttgcc
    45001 ggaatttttt tatggttttc gctaaaagaa ggacgtttta tcgcgtactt gtgtattttg
    45061 tgtagcataa cggtatccat ttcttatagg ctacaagagt attcattttt agaggaaaaa
    45121 acaacatctg cgcaaattac tgtatttaca gatacgattc gtgcaaatgg taattttttg
    45181 acaatggaag gaaggttatc agagaataaa caaaagctcc agctttctta tcaagtaaac
    45241 acagaagcag aattgaaaac atggcttaac ttccgaggaa agggaataga attgactgct
    45301 gaaggcgagt tcatctctcc agcaaaaaag cggaatcttt ataattttga ccaagaagct
    45361 tacttcagga accatagaat ttctggacgg ttccaaattc aaaagattga acagatcacc
    45421 atgcaaaatc actggcgaaa ctggcttcag agaaaaagag gatcttttat ctcctttgtc
    45481 caatctgaat ttccgcaaaa aacaagtgta tatattaatt ctttattatg gggctataaa
    45541 gatgcaggat tcagagaacc agaagaaatt tttagggaga gtggtttgct gcatctgttc
    45601 agtctatcgg gtctacacat ccaattttat ttagggtggc tgtattattt gtttcgacgt
    45661 atcggatggc cactacacgt cagtattatt ccgttgagtc tactaactat ctgttatgtt
    45721 tctattgcag gaagttctat ttctgttttg cgtgctagtt tgctgttttt attgcgattg
    45781 ctagtcaaat tgctgaataa gcattattcc accatggact tatttgcagt tgtcttttgg
    45841 cttcttttac tatttgatcc tcgatttctt tttcatgcgg gtggacagct tagttttttc
    45901 atgagttttt tgtttatcct gatttctttt gatggagatt ggttgaaaaa aacggcctct
    45961 cacgtcctgt ttactatgat cacgatgccg ttgattgtat ggcattttta tgagtggcct
    46021 attttaggta gtctttttac attactgatt gcaccggtat tcaagtttct ttttcttcct
    46081 ggtgtgttat ttctcacact cttcaatcgc tggctgccgg aaactttact tttgctgata
    46141 gaagagggat taatcttatt tgagcgaata atcgattttt cttcagggtc gtctctcatt
    46201 ataggacgtt tgccccttgt gctatctggg atgtatattt tcggattact gatttgtatg
    46261 gataggttga aagaacaacc tgtgaaacac ttgttttatg ttggtctttt ttcttttatt
    46321 tttttgactt tgccattttt acgcttttct tcaacgatcg cttttatcga tgtcggtcaa
    46381 ggagacagta tctttttgca aagtcctttt cgaaaagaaa cgattttgat cgatactgga
    46441 ggtcagttac actttgaaag agaaaagtgg gcgcaaggta tgatacgtcc tcctgctgaa
    46501 agaaatatcg ttccatatct aaaaggtcag gggataagtg taatcgataa actcatcttg
    46561 acacacgacg atacggatca tgtgggagaa ttacccacgt tatctcagca ttttactatc
    46621 aaaaaaattt atatcggttg gggcgctgga cgaaatgagc cattacaaag gcatttatct
    46681 gaagctcaaa aaaatggtac tgagatcatt gaaatcaaac atggggacag gatcagcggt
    46741 tattatgatc tttatgtatt gactcctttt gaaaagggag agggaagaaa tgaagattcg
    46801 attggtctat ggatggaata taacaatagg cgctttttat ttttaggaga tttgaatcaa
    46861 gcaatggaaa aacaattgct tttgatttat cctaatctga aagccgatgt agtcaaatta
    46921 ggtcatcacg gtagccgtac gtcaagtaac acagattttc tttcccatat tgaagcaaaa
    46981 catgggatta tatcctgcgg cgtaaataat cgttatggtc acccgcacag cgaagtattg
    47041 gagacactag aagaaaatca gataaaaaca tggcgaacgg atcaacaagg aatgatcacc
    47101 tatcgctggc atccagtttt tcatcctcat gggctagtgg aaacaatgat agactagtaa
    47161 ttctcatctg ctcatggtag gataattttt gaaagtggtg agtaatttga gtatacaagc
    47221 agagttacaa aaaatacgta aagaaaaact tgcatcttgt tacttgattt taggaacaga
    47281 aaagtttctc caagatcaag ttcggacaga aattgtcaaa aaaatccaat tagagggcga
    47341 agatgactta aattttttaa gttttgacat ggaaaatgca agtttagatg aggtagtagc
    47401 tgaagcagag acgttgccgt ttttcggaga tcaacggtta gtattcgtag agaatcctta
    47461 ttttttaaca ggtgaaaaag taaacaatgg aatcgaacaa aatactgatt tattgacggc
    47521 ttatttgaaa gaaccattag aatcgactgt attagtattc tttgcgccat atgaaaagtt
    47581 ggatgaacgg aaaaaagtaa cgaaacaatt gaaaaaaaca gcaattatca tcaatgtcca
    47641 acagttgaat gaaaaagaag tacgtcaata tctgatgaat accttagaga attcctcaat
    47701 caaaatggaa cgaagtgcaa ttgatttatt cttgaggttg accgacttag atttatccaa
    47761 aatgatgaga gagttacaga aattggtcct ttatggacaa aatcaacagc aaatcacggt
    47821 aagagaagta gaagaattag ttcctaaaac gttagaacat aatatttttg acatgaccca
    47881 atatatttta aaagggaaga cggaacaagc tttgcgttta tacgaagatt tagttatgca
    47941 aggggaagaa acaatcaaaa ttaatgcgat tttgctttct caattacgtt tatttttaca
    48001 gacaaaattt cttgtaaaga ttggttatca gcaggcaaat attgctgaaa cattgaaaat
    48061 ccatccatat cgtgtaaaac ttgccatgca ggaagtaaaa aaattcgatg aacatttgct
    48121 ggtacagttg tttgatcaat tagttgagat ggattatcaa atcaaaacgg gacaaatcga
    48181 aaaagaatta agttttcaac tattcgtttt gcgcacaggg cagttgttaa gaaatcgata
    48241 agaagaaaga cgagggcaaa gcatgcggga aggtcgtttg tttttgtcct ttttttgaca
    48301 aataaaaaaa tcggccgaag ccgattcttt tatttagcga tttttttgct taaacgagat
    48361 ttgtcgcggt tagctttgtt tttgtggatt agaccttttg attcagccat atcaatagct
    48421 ttaacagctt ctttatataa cgcatctacg ttgtcagcac ctgaagctac agcatcttca
    48481 aattttttga ttgcagtacg catagcgctt gtttgagatg aatttttcac attagcgttt
    48541 tcgcttgtac gaacacgttt gattgcagat tcaatgtttg gcattagttt cacctccgat
    48601 aacttaagtt cttacgcgtg ttaccgcata attcaacatt cattattata cctaaaggca
    48661 gcgtgctttg caatatgaac atgacaagtt tttttcctta acagtctttt attaggattt
    48721 tttttcagta aaaacggata gtacaagctg aaaaaaatca aaaagacgct attgtgggag
    48781 gcaatagcgt caaaccaaac tagattttta tttatctatt taaacaaagt ttgaatggga
    48841 atgtttggta ctaagttatt atataacaaa gagaaccgtt tgcaaagttt tttttgaaaa
    48901 gggatacgat tccctgttgt tctttgtttt tctattaaga aactgcagtt attttataac
    48961 cagtatcctt tgatcagtaa aggctattct ggtgtaccga ttattttaat gtattcatcg
    49021 atatttttta tcaacatttt ttttatgacc aactggttcc gacggttcca tttgccactt
    49081 acttccagca catatttatt taggggcaaa cgtaagatat attttgccaa atagcgatct
    49141 ttaagcaggc cattgatcac acggtcctca agctgcaagt tgatcccagt cagcatcatt
    49201 ggctgttctt gtaaaacgta cgtatcaatt aaaagacctt caaaagtttc cacaagcgtc
    49261 ttcctttctt ttcaaagtaa cctgaaaaca ggcactaatt cttccatttt gatattcgtt
    49321 gaagtggatg cgatcattct ttcttttgtc cactgtaatc tagtataaca aaaaagagca
    49381 gaagagccaa aaagaaaaaa gagcatcgaa ttctatagga agtctcattg gcacggccta
    49441 aattattaca aaacattgat taaaaaaagc ccctgcatcg caggagcatc ccctatatcg
    49501 ttttaatagg tcaatcaaaa agcagtatca aacacatttt gtatcaaatc aggaaataat
    49561 agataagcta agcccagaat caaaagtacc gctagaagaa accagccgat tgttcctatg
    49621 aaatacttta atttttcgaa cattgtatca cctcgttgtc agtatatcac ggatcagtaa
    49681 attgggggtg ttaagaatct cctaaaatag acaaaatttg ttctattttc ctaaagcaaa
    49741 tacttgtaag atacagtaag tgataccaga agcaatgacc ggtccggcgg cgattcctct
    49801 taagaagaca acacctaaaa tcgtgccgaa aacaagtgca acagtgattt gtggatcaga
    49861 agcaatcaat cctacaccct tggaagataa gacagccact agcccaccgc aaaaaacagc
    49921 tacccagcca ataggggatt taaaggcttc taatagatca cgtagaccga tttctcctgt
    49981 tgcgataggg attagaatag ccgctgtgat gatcgtcacc ccaatattga ttcctttgcc
    50041 ttgaagccaa gggaaaaagg aacgggaggc tggtatgagc ttcataatca aaacaaaagc
    50101 tgccgctatc atcagacttt gatttttagc taaaattgct acaagtaaaa taattcctaa
    50161 aaaaagccaa ctttccatga aatatattcc tcactttctt cgaaacaatc ataacatgtt
    50221 tttagaaagt tacaaaagta ggaattcatc cttcaagacc tattcataag ctgttttttt
    50281 cataaaataa acaaaatcat aaaaaaacac tttgcttatt tgacagaaga cagccgcgct
    50341 ttgtatagtg gacaagactt acattttttt gaagaatcag aaagatcagg taaaggtctt
    50401 agtaaacgca agccattcag aataaccaat attgtgcttc cttcgtgtcc tacaactcca
    50461 agaggtagat ttaaaaattg caggaagtta gaagcaatca acaagagaat aacaagaatc
    50521 gaaaaaataa tattttgttt gatgatccgc cgcattttta aagatagccg atgactgtag
    50581 acaaatttat ttaagtcgct tttcattaag acgatgtctg cgatatccat agcggcatct
    50641 gtcccttgcc ccatagcgac acctaaagaa gcggctgcta aagcaggcgc atcattgact
    50701 ccatcaccaa ccatcgcatt tacttggtaa agttcattct cttttttgac tagttgtgtt
    50761 ttttcttccg gagtacagct tgcatagtaa tgttcaatcc ctacttgttc agcaatggcc
    50821 tttgctgtgc cagaatggtc gccggttatc atacttgtat ggatgttttg ggatttaaag
    50881 taggaaatta cttgttgggt atttgctttt ggaatatcta gcagacctaa aacagcaatt
    50941 aactgctgat ctttagaaag ataaatcacg gttttgcctt gattttccaa acgttcgatc
    51001 atttccgcaa tctctttgct gattatcatc gtctcaggat catatgcgtg cttgccaact
    51061 ttccattgcg cacctaaata ggtagtttgt aatccaaaac cagtaatttc ttctattggt
    51121 aagtattgga tttcttcagg tattgtgcaa tcgaaatatt gcaaaatcgc atgagcaagt
    51181 ggatgcgtcg ttttttgttc catagcaaca agaagttgtt gtgccaaatc cttttcatca
    51241 aagaaaaagc tgtcagttac aactggtttt cctttagtga gcgttcctgt tttatcaaag
    51301 gcaatcgctt ttaattcaga aagcttttct aaatggatac cgcctttgat taaaatccca
    51361 ttttttgcag aatttgaaag agcagctaga gaagctggtg tagcagatgc gacaagcgca
    51421 caaggagaag ccacaactaa taataccatt cctcgataaa agctttcatc ccaactccaa
    51481 cctaggaaaa agtgggggag aaggatcatt agaggaacag caagcaaaat caattttaca
    51541 taattatttt cgattcgttc gataaatgaa gctgtttgag ttggcgtatt ctgcgcttct
    51601 tctactaatt ggataatctt agcaaagaca gtttcggaac tcgtttttgt tactcgaatc
    51661 gtgatgggat ttccttgatt cagcgttcct gcatacatct catcgcctaa atatttttct
    51721 acaggcacag attcaccgct taatgcagac tcatcgatcg ttgcctgtgt gctttctaaa
    51781 aagccatcta tcggaacagc tgctccttta gcgacaaata ccaagttatc cacctttagt
    51841 tgagaaacat ctacttcttg catttgtcca ttttctttta ataattgggc tttttgtggt
    51901 tgaagattca tcaaagcagt aatttctttt tgacttttat tagttgtgta ttcctctaat
    51961 gcaccgctta aacaaaagat gaatgtcaac attgctcctt caaagtaatt accgatcaaa
    52021 caggcaccaa tagcagctaa agccatcaat aaatccacat tcagtgtccg atcattccac
    52081 aattctttca agccttccga tgtttgttta tatccaccga tgataatggc actgatataa
    52141 aaaagtgggg tgatggtaag agagaatcgg tcgaagataa aaccgaagat cataaataaa
    52201 aggcagccga ttgttgctgc aaaagctttt ttctgattag tcatcgttat tagacctcct
    52261 tgtcaaaaca aggatagcat aataaaaatg taattgataa taataacagc taaatgagaa
    52321 cgataatggt tatcatttgg tgattaagct tgatgttgtt tttattattt ataatgatta
    52381 ttattaaaga aaataaaaaa ccagaacatt tctcaaataa gagaagtgtt ctggtttttt
    52441 ctacattgca ataaaccaat aaccaatcaa aatgatacca aggataatac gataccagcc
    52501 aaaagcggta aagtcgtttt tcttcaaata gcttagtaag aatttgatag ctaagacgga
    52561 aaccacaaaa gatacgaatg ttcctacaag aagaacaaca gtttcttcca ttttgaatga
    52621 attcccttca gctaaatatt tgacgatctt caagccgctt gcgccaaaca tgacaggaat
    52681 ccctaagaaa aatgaaaact ctgtagcgac aaaacgcgaa gcaccaatca agatagatcc
    52741 taggatcgtt gcgccagaac gggatgttcc gggaacaagt gccaagactt ggaataaccc
    52801 aacaagaaga gctgcttggt acgtaaagtc attcagagaa gtccaacgag gtgttttgtt
    52861 tttgttgcgt ttttcgacaa taataaaggc aataccgtaa acgatcaaaa caatggcaac
    52921 tggtaagaac ttgtggaaat ttgcttctaa ccaatcatcc aaaggcaaac caatgatgat
    52981 ggctggtatg caagcaacga tcactttaaa ccaaagtgtc cacgtatctt ttttttctac
    53041 cgttgattta cttggagaaa atgggtttaa cttgtgaaaa taaagaacga cgacagccaa
    53101 gatcgcccct aattggataa cgacattgaa catcgacata aattgtgaac tggcatccag
    53161 tttgatgaat tcatctgcta ggatcaaatg accagtacta ctgatgggca gccattccgt
    53221 tattccttca ataataccga gaatcactgc tttgataata tttgcaaaaa acataaattc
    53281 cttccttccc aattaagata catcttatag tataccgtta ttttttgaga aacccaatct
    53341 gttttttaat attaagaaaa acttgagaaa taaagcagat aagtacacga agagaaaaaa
    53401 gaagacaaag ccctcgttca gactttgcct tttatgattc tctggtaaaa attaaaatat
    53461 ccccattata gaaacgagtc gcgactatgt gttttcccgt tatcgatata agacgtatca
    53521 ttgatgccgt ggatagaaaa tcgaccgttt gcataagtga cctttgttac gctgccattt
    53581 aaaagcccag cacgaacagg ctgtttagga tcgatcagat taagcaaaaa ggcgatcgtc
    53641 aaaccatgag atacgactaa aacatttcca ccaccatttt tttcgcagtg atgggcgata
    53701 tcttcaaatc ctgtccatac acggtctcgc aatgtttcat aagtttccgc ccacccagcg
    53761 gtatctaagt tgtatacagc attagcaatt tgttcaaaag aaacttctgt ggtaaacatt
    53821 tcatcatatg ttttaaaatt caatacacga gggatcacac cccacatttc catgtcatat
    53881 ccaccttcaa gagacccgaa acaccattct ctaatccttt tttcaataaa ataaggaatt
    53941 tcttttccct tagaatgttc tcctagaata atacgggcag tttcgattgc acgaccactg
    54001 tcactagaat aagcaaatga aaagtcgaca ttttttaacc cgcgacctaa ataatgaatg
    54061 ccttcttgtc cttgctttgt gaggggtgta tcacaccagc cttgtactcg ttcaattgta
    54121 ttgaacatcg tttttccgtg tcgtacgata taaagtgtag tttctgtcat tttattctcc
    54181 tcctaagtcg ttttaacgat tgaaaaaagg atttgtcctt ttttcctgtt caatcgtcgt
    54241 tgcatcgcca tgtcctggat agactgcaaa ttcatcaggt aatacaaaca gctgggtccg
    54301 aatactatga agtaattgtt ctaaattccc tgtatacaga tcggttctac cgatacttcc
    54361 tctaaacagg gcgtcgccag aaacgacaaa atcatcaaaa ataaagctga cgcttcctat
    54421 agaatgccct ggggtaggga cgacgcgaaa agacatgttt cctaaagtat aagttttcat
    54481 ttcaaattca tattctgcag gcgagacaat aacatcagca atatcatcat gtctaccgag
    54541 tccagaaaga ttcaaaatcg gatcacctag ccatttttgc tctagtgggc tgacataaac
    54601 tgggatttga taatacgcgc gtaaaggttc cactgcaccg atatgatcgt agtgagtatg
    54661 ggtaagcaaa atcgctaccg gctgttggtt tgtttttttg atttcttgtt tgattcgttc
    54721 cgcatcttct ccagggtcaa tgatcaaaag tgcttcttcg ttgtagacca aataacagtt
    54781 ttcttcaatc attcctgttt ttaatctttc gatatgcatg tgcattcctc cttgatagcc
    54841 aaaacttctt tcatccatta gtataacgca ttcattgcta ggaaacaaaa acaggtactt
    54901 atttctcttt acttatctga attatcagac tatatgaaaa gtatttggat attctaaaga
    54961 gaaggaaagt aagttttcat agcattttaa tatgtccttg ttacattaga ttcatccaaa
    55021 aatccaaatt ctatatccta tatccctgcc taatcagcag ggtgtttttt tatgtttgga
    55081 aagagagctc tttttgctaa actaggtttt ttcaggtaat cttagagaga aagaggtggt
    55141 ggaaatgatc aaacagtcaa aaatatctgt gcggcactta gtagaattta ttttgcgacg
    55201 tggaagtatc gacaatcgta aaaaaagtaa ccatactgca ttagaaggag cgagaatcca
    55261 ccgcaagctc caaaaagatg cgggagaaaa ctatgaaaaa gaagtctttt taaaaacaac
    55321 agttcaatta gatgaatatt acctgatcgt tgaaggccgt gcagacggta ttttcaaaag
    55381 agacggtatt tattatatag atgaaatcaa aacctccgaa ccacgatttg aagatttaga
    55441 accagaacaa gtggaacttt tctttcatca agcaagggtg tatgcctata tctatagtca
    55501 agaacatgat ttacaagaaa taaatctgca attgacttac ttccagacgg cagaagaagt
    55561 gatcacgaga aaggttgaac atcagacaag agagcagtta gaaacttttt ttaaaaagct
    55621 gactgaagat tataaagaat ggcttgtttt tcaagaaaac tggcgcactg tacgcaatgc
    55681 ctctttgatg gctttgaaat tcccccatga tgagtatagg aaaggtcagc gtgaactagc
    55741 ggtagctgct tataaaacga tccgtacgaa acagaaattg tttgtagaag cacctaccgg
    55801 aacaggaaaa acaatctcta cgttattccc cgctttgaaa gctgtagggg aagaagaggg
    55861 agaaaagatc ttttatctaa cggctaaaac aataactaga caagtagctg aagatgctat
    55921 gacagcatta aaagatacag gagctgaagt aaaaagtgtc actttgacgg cgaaagacaa
    55981 gatctgcttt ttagatgaga cgacctgtaa tccagatcag tgcccatatg ccaatggtta
    56041 ttacaatcgg attaatgaag gtttatggga tcttttgaat catgagaatc agatcactcg
    56101 tgaagtcatc gaaacttatg caagaaagca tacactttgt cctttcgaac tatcattaga
    56161 tgtcagtatc tggtgtgacg taatcattgg ggattacaat tatttatttg atccaactgt
    56221 ttatttaaga cgtttttttg aagatgaaaa aaacgaggac tatctgtttt tgattgacga
    56281 agcacataat ttggtgaatc gttcccgaga gatgtattcg gcagaactat cttatgaaaa
    56341 aacgaaacga agtaaggaag ctataccaaa ggaattcaaa aaacttcatc gccgtttcaa
    56401 caaactatta aaagaatttg attcgatccg agaaatagca aaagaagatc attgggatta
    56461 tcatcatcaa aaagcaccgg ctgaatcttt agtaaaggca ggttatcaat taagcgaaaa
    56521 aattaaagaa tggctggcag aatttcctga gcacccatca caagaacaat tgcttcctta
    56581 ttattttgat ttgcttcatt ttttgaaggt cagtgaattt tatgatgatc actacgaaac
    56641 aacagtcgaa aaaacgtatc gcgatctgat agtaaaagag ttttgtattg atccaagctt
    56701 gtttcttgag cagtcgttgg ataaaggaaa aagcagtatt cttttttctg ctagtttttc
    56761 accactctct tattatcagg aaacactggg gggacaaaaa agtctggctt acaaactgcc
    56821 gagtcctttc ccagaaggaa accagcaagt tttcatcgca aattacctag agacgactta
    56881 tcgaaaaagg gaacacagtc tggcaaaatt agtagagacg attcatgctt ttgctgatgg
    56941 aaaggtcggg aattatttcg ttttctttcc ttcttatcaa tatttagatc ttgcggtgga
    57001 agcattcaga cagcaatatc ccgacagcaa tgtgctaatc caagaaacgg acatgaatga
    57061 ggaagaacgc gaacgatttt taacaaaatt tcaaacaaat cccgctgaaa cattgattgg
    57121 attttgcgta cttggcggga ttttttcaga aggaatcgat ttgagagggg accgattgat
    57181 cggcagtatg atcgtaggtg taggtttgcc gcagatgaat catgagcagg aactgatcaa
    57241 atcatattat gatgagaagg aacaccttgg atttgcttac gcttatcagc ttcctggaat
    57301 gaacaaagtc ttgcaagctg gtggtcgagt gattcgtggc atggcggatc aaggaatcgt
    57361 tgtattggca gatcaacgat tttctagttt ttcttatcga cgtttattcc cacaacattg
    57421 gcaaacagca agagaagtac gaagtgttgg ggaattggaa gaaggaatac agcgtttttg
    57481 gttatcaaaa gaagcagtaa atcaaaaaaa cgaggaatga cagacgtcag cctcgttttt
    57541 tgattaacga tagttagtga attgcaactc gattggtaag tcaagtttac gtaataaagc
    57601 aatcacagct tgtagatcat cacggttctt acctgtcact ctaatctgat cttcttggat
    57661 ttgtgctttt actttcagtt tttcattttt gatagctgta gtgattttct tcgcgttttc
    57721 acgatcgatt ccgttgacca aatcggcagt ttgtcgagct ttgccaccta gagcgtgttc
    57781 tgattcggaa aaatggatat ttttgattgg cacatttctt ttgatcagct taccaaataa
    57841 tacatctttg atctgttcga ttttgaaatc atcatcgctc aatacaacta gattgctgtt
    57901 ctctaatttg atttctactg tagaatcctt gaagtcaaag cgattggaca attcttttgt
    57961 tgtttgctga atcgcatttt ttacttcttc tgtattgact tctgatacaa tgtcgaagct
    58021 agcatctttt gccataggaa ccctcctgat atacatataa atatttacca tacatctatc
    58081 ttatcatagg attagggcag attcttacct gtttgctaaa attcttctca tttgagttcg
    58141 aagtatttta ttttaataga taaactgtta ttcttacatt tggaatacca aagtagggga
    58201 gaggtgcttg tgagtaaaat tatgactgcg tatcataaaa atgaaagatt aaagaaaata
    58261 gtggttattt tgataaccgg attgaccgct gcggtcgctt taaattattt tttgattcca
    58321 gccaatgtct tttctgcagg gatgaatggg atcgctcaaa tcatttcctc gcttttatat
    58381 gaatggtttc atatcaagat agacacagga acatttattt ttcttttgaa tatccctgtg
    58441 tttgtattag ggtttctcaa agtaggaaaa cgagcaacga tccttagttt tgtgaatgtt
    58501 gtatgtgtat cggtgatgac gatgctgctt ccagtcggac agatcactga taatattttg
    58561 atgaatgccc tagtaggcgg tgttttatta ggtcttggcg taggattatc tttaaaaatg
    58621 ggctttacaa ctggtgggat ggatatcatc tctcttgtac tttcacaaac aactggaaaa
    58681 acagtcggaa actacatgct gattctaaat ggtatcattg tagtcatcgc aggcttcttc
    58741 tttaactggg aaagtgcctt gtatacgatt atttccattt atgcaatgac tcaagtaatt
    58801 gatgccatcc acacgagtca tcaaaaagta acagcaatga tcgttaccgt caagccagaa
    58861 gaggtaacag aagaactagc aaaacggatg gtacgtggaa tgacattact gccgtctgtc
    58921 ggtggctatt caaaaaaaca agggaacatg atcatgatgg tcatcacccg ctacgaaatg
    58981 tatgatcttg atcagatcgt tcatgaaatc gacgacgatg catttatcaa tattttacca
    59041 actcattcag tatttggccg gtttgcaaat gaaaacgaac aaaaaatgta tcgaacaact
    59101 ggcgtattgc cagaaataaa aaatcgttca caaaaaaaat gaggaatcag gtttatttta
    59161 gaataaattt aatctattac atctaataag aacattttta taaatttaaa cgagaatctt
    59221 acttctaaat tctcatttac aagcagctaa aaaaagagta tgataaataa aaatcgtgtt
    59281 aaggagtgtc gtacgatgag cgaagcaaac caagaacggt ctggacaaga aatagaacta
    59341 atcaaagaac gtattcttgc tgccttggaa atggtgattg atcctgaatt aggaatcgac
    59401 atcgtcaatt taggcttgat ttatgatata gaattcaatc ctgaaaatgg agaaacagtc
    59461 attaagatga ctctaacaac tatgggctgt ccattagcag atattttaac agaatctatc
    59521 catgacgcat taaaagaagt gccagaagta acgaaagcag aagtcaaact agtctggtat
    59581 ccagcatgga cgacagataa gatgagccgt tatgcacgga ttgcgttggg gatacgatag
    59641 aaatcttggc tgactagcta tgagaagcaa ataggaaaaa caaaaaagcc ttttatcctt
    59701 tctagaagaa aagagataaa aggtttcttt gtttataaaa ttttgtctgc tatattataa
    59761 gttaattaaa taaatgtgtt ctattgataa aggacattca aatccctttc cttttggaat
    59821 ccttcttttt tacatcagtt tgattttcgt atagtattct ttctcatctt cacgataaat
    59881 cgcagcccca tttttttgtt gtgctttaag actgccaaga ttttttttat ttacagacaa
    59941 aagtgcctca tcaatgccga ttttttttgc ctcttgtagt actaatgcta atccttgtgt
    60001 ggcatatcct tttttacgat aattagggga gatgccgtaa ccaatatggc cagcgccgtt
    60061 tcttaatgtt tcgttcagtt tatggcgcaa attaaaaatt cctacatact catgttcatc
    60121 actttctaaa ataaagacgg ttgcgggaac gtaactctca ggaagatcga ttcctaaaga
    60181 cgttttttcg cattttttta cataatctaa aaattcagca aatgtatagc cataagcatt
    60241 gttgataaat ccactctcat ttggtccaaa gctagtttgt agctgataag ctttctttaa
    60301 atctgcttcc catagtttga tcagtttcat cgtattcacc tctttaagta accttattca
    60361 tttgttttct actatagcac tattgttgta aatagccatg cctattttta tttattgtgt
    60421 catatcgtat taagaatcat cgaacaatac aaatatgaat tacaataaaa aaattatttg
    60481 aagttcgttc attcgttact tatgatctct agaagaaaga aaacgtgaat tacttcagcg
    60541 tctagaattc cagaaggata gtaatcaaca gaagaaataa tcaatatcca aatgaaagaa
    60601 gatagctgaa tcgagaaaaa gaggaaaaaa gaaatgaaga aaaaaataaa atagttacta
    60661 atcccagagt cgttcgttta acattgaaat cgatcatatg gataaaacag attttttcac
    60721 caaccctcaa tagatgatgg agttgctcgg atgaattatt tgtgtagatg gcataaggga
    60781 gggcgtacag aaatgaaaaa gaacaaaaat atgttcttga caaaaaacac atgtaatcct
    60841 aaactaaaag atgtgatgcg gctatggcgg aattggcaga cgcgctagct tcaggcgcta
    60901 gtgagggtga cctcgtggaa gttcgagtct tcttagccgc ataatttgtt tttttataaa
    60961 gagaaggtac acctggagcg atgagaaaga aaataacata ttatctaaaa gaatatagga
    61021 aaaattttaa acaacggaac cagattcaaa taaatcaaaa aaaatttgtg tgaaggtggg
    61081 acagtttaaa acctaataga ttgattcaaa tagtagattt atagattctg atacaagaaa
    61141 tactggcaaa cgatagttaa ggaataaaga ctaaacttaa actcaaaaag aggtcatgcg
    61201 aaagaataaa tcgcatgacc tcttactata ttttgaatgt gtttaaacgt tcaaataatg
    61261 aatcttagta ccaaccgttt gcttcccaga atgctttcgc cgcttcccaa gaaccataac
    61321 gtgaagtaac atattgttct gctactcttt cttggtttgc agcagagtag tcaccattta
    61381 agtaagaaga atctaattgg taacggccga tgtaacgtcc gttcgttgct gtgtaagaac
    61441 cgcttgattc tttttgtgcg atccattctt ttgcagagct tgtacttgct ggagtagcag
    61501 cagtttctgt tacagcagga gcaggttgtg tttcagcaac aggcgctgct tgtgtttccg
    61561 tttgaaccgt ttcttgtaca acaggttgtt cagcttgaac aggttcagct tggactggtg
    61621 cttcttgaac ggctgcttga ggttcagcag ctgcttgtgc agagccttct gttgggattg
    61681 ttaattgttg tcctgagtag atcaggttaa tatcagaaat tgaatttgat tctgcaatgg
    61741 cattgatcaa ggagttatca ccaacgtatt tttgagaaat cgttgataga gtatcacctg
    61801 attgaacggt ataagcttcg tccgcatgag cagtcgttcc catgaagaat gcagcgccgg
    61861 cagccaaagt tgttccaaaa agtaaagttt taagtgatgt catgaaaaat ctcctttatt
    61921 cgttaaaaag ttttatttgt tgtgttcaac gaggaatact ttaacacgtg aaaatatttc
    61981 ataggtaaaa gaagcatgac aatttatgac aaatccacgt tttttgtaac agaatgatgt
    62041 tcgctcgatg tgaaaaatga tgaggaattt cacataatgc agaaataatg ggattagaac
    62101 aggtgttctg atgagaaaag aaatgtataa ataacttgaa agaaattgct tttgttcatc
    62161 attttattta catattgcgt atattttttg tatttttgct tgagatgtta caataaaaga
    62221 aaaaggaggc ggttccaatg agtaaaagat accagaacat catggtagca gttgacggat
    62281 caagacaatc gatcaaagcg ttcgctgaag cccttgactt agcaaaggac aatgaagccc
    62341 acttatttat cgtgtcaatc atcaacaaag ttgagctgac ccatagtgcc tatgcctttt
    62401 caaaaatcta tgcagatgaa aaacaaagaa cagaagtagc catgctgaaa aaaatcaatg
    62461 atgccaaaga gtacggcatt gctgagatcc acgcaatagt tgaaactgga gatccaagaa
    62521 atttgattgc caatgtcatc cctggacaag aaaatattga tttgatcgtt atgggagcga
    62581 caggaaaagg tgctatacaa caagcattag ttggatcgac cgcttcttat gtcgtatcac
    62641 atgccccttg cagtgtgttg gtcgtgaagt aatgagataa gggaggaata gaaaatggtt
    62701 cgtcctcaag aagtccgtgc gccaaaagaa aaaatagaaa ttttagcaat tattgaagac
    62761 ggcacacaaa caaagaaggg atactcgatc gctttagtaa agtggaaagg aaaaaaaggt
    62821 gttgctctga gatgggatgg agataaccaa caagataaag gattccctgt cacagctaac
    62881 ggttatcatc cagcgtggtt tgttctgcct gataaattta tggaattata cagctatgat
    62941 tatgcaagag ccgcagcatc aatcaaagca ttagataaat taacagaaga gcagaatgaa
    63001 atggaggaaa aataaaaaag acgaaccaat cagcctttag aaaactgatt agttcgagga
    63061 gtaaaaatga aaaaaggtta tttgggatga aactagaata atgcgtataa cttaaataaa
    63121 acttaaagca ataaaatggc aagagggtga ggcaaatgga agcaggaaaa gtattacagg
    63181 aagtaaaagc actatgtgca gataaaaaat atgaagaagc gaaaagcctg atcgaaaaga
    63241 acaaagaaaa tttggaagaa aagtacccga tcgcacaaga atttatagaa ttaaaacaag
    63301 gaacgatcct tcaccgattc aaacattttt ttggtataac agaatagaaa aaacgattaa
    63361 agatcggcag aaatttgctg catctttaat cgttttcttt ttaaacatgc gagggattca
    63421 attctgattc ttatataaaa aatagatcca aataataaga aaaattactg aaagcgtcaa
    63481 ttcgatgatg tgtgttatta atacagacgt tgtttcccaa tgcctaaaag aaaaaatttg
    63541 ataagtaaaa tatacagcag gtaaagaggc cagtaaaact gaaaacttct tttttgtcca
    63601 ttttatgtaa tagaaaagaa tgcttatcat aataaaaaaa ggaatataaa aaacaaattg
    63661 accgatcgcg atcatactat tgcctccgat aaataaagtc catgatacaa aataacactt
    63721 tgtgcgaaat ggcgcaagca gttttgtgga tttatccggt aaaatctgta tcgattttga
    63781 aattagagga gaaacttgct ataatcaaag tgaaagaagg agtgggattt tcatggatca
    63841 tgtagtgtta gaaatcgatt tgcatttgat caataatatt cgggtgattt actatgttgt
    63901 aagtaacagt gtcgaacaac gtgtactgac gaataaaata aatggtattt tagcaaagaa
    63961 agacgttcac cgattcaata atggtgaagg aagttattat agtatcccag tagaaaaaat
    64021 tatttatacg acagtcaaag tcagagaaga tctagatacc aaaaaagcat atgaacctat
    64081 ttttacaact tattgattga cagcagatgg aggaaaaaaa tgaatccata tgaacaactt
    64141 attcaagatt tgatcgatgg aaaaatcgaa aagattgatg taaaaagaga agaattaatg
    64201 gcttttcgag aagcgtggct gaagttggag aatcgtaaat atgtggtggg aaaagcctca
    64261 ctgaacggca atgtgactta tcattacgat ccgacacgtt tattttagta tgaagtattc
    64321 agaaaagaac caaaggagga cgatgcagca gcattgtcct cctttgattt tacaaaagtg
    64381 aaagttttac ttatttgaat agatttttaa attt
//
LOCUS       DADGHT010000003        61938 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.003, whole genome shotgun sequence.
ACCESSION   DADGHT010000003 DADGHT010000000
VERSION     DADGHT010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61938
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.003"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            275..1111
                     /locus_tag="JX887_000141"
     CDS             275..1111
                     /locus_tag="JX887_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAX1256161.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLINLYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            1175..1606
                     /locus_tag="JX887_000142"
     CDS             1175..1606
                     /locus_tag="JX887_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1256162.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(1668..2990)
                     /locus_tag="JX887_000143"
     CDS             complement(1668..2990)
                     /locus_tag="JX887_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAX1256163.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3144..4784)
                     /locus_tag="JX887_000144"
     CDS             complement(3144..4784)
                     /locus_tag="JX887_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAX1256164.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            5117..5587
                     /locus_tag="JX887_000145"
     CDS             5117..5587
                     /locus_tag="JX887_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAX1256165.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            5809..6912
                     /locus_tag="JX887_000146"
     CDS             5809..6912
                     /locus_tag="JX887_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAX1256166.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            7196..7876
                     /locus_tag="JX887_000147"
     CDS             7196..7876
                     /locus_tag="JX887_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAX1256167.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            7966..9000
                     /locus_tag="JX887_000148"
     CDS             7966..9000
                     /locus_tag="JX887_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAX1256168.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            9014..9349
                     /locus_tag="JX887_000149"
     CDS             9014..9349
                     /locus_tag="JX887_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256169.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            9333..11813
                     /locus_tag="JX887_000150"
     CDS             9333..11813
                     /locus_tag="JX887_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256170.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            11869..13428
                     /locus_tag="JX887_000151"
     CDS             11869..13428
                     /locus_tag="JX887_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1256171.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            13425..14789
                     /locus_tag="JX887_000152"
     CDS             13425..14789
                     /locus_tag="JX887_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAX1256172.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            14960..16030
                     /locus_tag="JX887_000153"
     CDS             14960..16030
                     /locus_tag="JX887_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1256173.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            16045..16713
                     /locus_tag="JX887_000154"
     CDS             16045..16713
                     /locus_tag="JX887_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256174.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            16733..17311
                     /locus_tag="JX887_000155"
     CDS             16733..17311
                     /locus_tag="JX887_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1256175.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            17712..18623
                     /locus_tag="JX887_000156"
     CDS             17712..18623
                     /locus_tag="JX887_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1256176.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(18711..19628)
                     /locus_tag="JX887_000157"
     CDS             complement(18711..19628)
                     /locus_tag="JX887_000157"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAX1256177.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            19830..20267
                     /gene="zapA"
                     /locus_tag="JX887_000158"
     CDS             19830..20267
                     /gene="zapA"
                     /locus_tag="JX887_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAX1256178.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            20326..20874
                     /locus_tag="JX887_000159"
     CDS             20326..20874
                     /locus_tag="JX887_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAX1256179.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            20989..23349
                     /locus_tag="JX887_000160"
     CDS             20989..23349
                     /locus_tag="JX887_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAX1256180.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            23436..23750
                     /gene="trxA"
                     /locus_tag="JX887_000161"
     CDS             23436..23750
                     /gene="trxA"
                     /locus_tag="JX887_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAX1256181.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            23932..25710
                     /gene="uvrC"
                     /locus_tag="JX887_000162"
     CDS             23932..25710
                     /gene="uvrC"
                     /locus_tag="JX887_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAX1256182.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            25855..26754
                     /locus_tag="JX887_000163"
     CDS             25855..26754
                     /locus_tag="JX887_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256183.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            26747..28009
                     /locus_tag="JX887_000164"
     CDS             26747..28009
                     /locus_tag="JX887_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1256184.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            28170..30068
                     /locus_tag="JX887_000165"
     CDS             28170..30068
                     /locus_tag="JX887_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAX1256185.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(30398..31117)
                     /locus_tag="JX887_000166"
     CDS             complement(30398..31117)
                     /locus_tag="JX887_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAX1256186.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            31454..31786
                     /locus_tag="JX887_000167"
     CDS             31454..31786
                     /locus_tag="JX887_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256187.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            31773..33776
                     /locus_tag="JX887_000168"
     CDS             31773..33776
                     /locus_tag="JX887_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAX1256188.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            33795..34265
                     /locus_tag="JX887_000169"
     CDS             33795..34265
                     /locus_tag="JX887_000169"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAX1256189.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            34286..34870
                     /locus_tag="JX887_000170"
     CDS             34286..34870
                     /locus_tag="JX887_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAX1256190.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            34885..35871
                     /locus_tag="JX887_000171"
     CDS             34885..35871
                     /locus_tag="JX887_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAX1256191.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            35861..36172
                     /locus_tag="JX887_000172"
     CDS             35861..36172
                     /locus_tag="JX887_000172"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAX1256192.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            36194..37975
                     /locus_tag="JX887_000173"
     CDS             36194..37975
                     /locus_tag="JX887_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAX1256193.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            37968..39344
                     /locus_tag="JX887_000174"
     CDS             37968..39344
                     /locus_tag="JX887_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAX1256194.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            39351..39986
                     /locus_tag="JX887_000175"
     CDS             39351..39986
                     /locus_tag="JX887_000175"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAX1256195.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            40016..41371
                     /locus_tag="JX887_000176"
     CDS             40016..41371
                     /locus_tag="JX887_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAX1256196.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(41563..42957)
                     /locus_tag="JX887_000177"
     CDS             complement(41563..42957)
                     /locus_tag="JX887_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAX1256197.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            43049..44020
                     /locus_tag="JX887_000178"
     CDS             43049..44020
                     /locus_tag="JX887_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAX1256198.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            44017..44799
                     /locus_tag="JX887_000179"
     CDS             44017..44799
                     /locus_tag="JX887_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAX1256199.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(44968..45339)
                     /locus_tag="JX887_000180"
     CDS             complement(44968..45339)
                     /locus_tag="JX887_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAX1256200.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            45473..45916
                     /locus_tag="JX887_000181"
     CDS             45473..45916
                     /locus_tag="JX887_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAX1256201.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(45959..46768)
                     /gene="yidA"
                     /locus_tag="JX887_000182"
     CDS             complement(45959..46768)
                     /gene="yidA"
                     /locus_tag="JX887_000182"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAX1256202.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(46787..48154)
                     /locus_tag="JX887_000183"
     CDS             complement(46787..48154)
                     /locus_tag="JX887_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAX1256203.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(48138..48968)
                     /locus_tag="JX887_000184"
     CDS             complement(48138..48968)
                     /locus_tag="JX887_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAX1256204.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            49131..49568
                     /locus_tag="JX887_000185"
     CDS             49131..49568
                     /locus_tag="JX887_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAX1256205.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            49644..50264
                     /locus_tag="JX887_000186"
     CDS             49644..50264
                     /locus_tag="JX887_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAX1256206.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            50453..50959
                     /locus_tag="JX887_000187"
     CDS             50453..50959
                     /locus_tag="JX887_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAX1256207.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            50976..51875
                     /locus_tag="JX887_000188"
     CDS             50976..51875
                     /locus_tag="JX887_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAX1256208.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            51962..52846
                     /locus_tag="JX887_000189"
     CDS             51962..52846
                     /locus_tag="JX887_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAX1256209.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(53038..53109)
                     /locus_tag="JX887_000190"
     tRNA            complement(53038..53109)
                     /locus_tag="JX887_000190"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53074..53076),aa:Arg,seq:ccg)
     gene            53169..54503
                     /gene="rpoN"
                     /locus_tag="JX887_000191"
     CDS             53169..54503
                     /gene="rpoN"
                     /locus_tag="JX887_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAX1256210.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            54706..55743
                     /locus_tag="JX887_000192"
     CDS             54706..55743
                     /locus_tag="JX887_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAX1256211.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            55784..56785
                     /gene="gap"
                     /locus_tag="JX887_000193"
     CDS             55784..56785
                     /gene="gap"
                     /locus_tag="JX887_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAX1256212.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            56895..58085
                     /locus_tag="JX887_000194"
     CDS             56895..58085
                     /locus_tag="JX887_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAX1256213.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            58189..58944
                     /locus_tag="JX887_000195"
     CDS             58189..58944
                     /locus_tag="JX887_000195"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAX1256214.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            59060..60358
                     /gene="eno"
                     /locus_tag="JX887_000196"
     CDS             59060..60358
                     /gene="eno"
                     /locus_tag="JX887_000196"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAX1256215.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            60757..61896
                     /locus_tag="JX887_000197"
     CDS             60757..61896
                     /locus_tag="JX887_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAX1256216.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        20466 a        10839 c        13054 g        17579 t
ORIGIN      
        1 aacggcaggc tcacgacctc tttcttaaac ggtgttcaaa agcttgcatc tgcggtaata
       61 agttcaacca aacgaaaatt atgaggagct atttttgttt ggctgttctt attacttgat
      121 gcaggacagc tttttcacaa cctcttttcg tttagcacta aatttcctta aaaagtagaa
      181 aagctttcga agcctcgttt gtttctttta ctgtataata aaagaaaaga gtaacaatcg
      241 ctaaaagata taaacaagag aaaggaaata caagatgatt ggtctgattt attttgtggt
      301 gatcgttctg gcgaacacag ttggcgctat ttccgggatg ggtggaggcg tgttgatcaa
      361 accgattctt gatcttatcg gcgcccattc tgttgcaggg atttcttttt actcaacagt
      421 tgcggtattc acgatgtcca ttgtttcgac tgtgcgacaa gtatcaagcg ggaaatcact
      481 gaattggcag attgtcggtt gggtatctag tggagctgtt gttggaggag tagtcggcaa
      541 cattgtattc gaagtttttt tacagttatt tgaaaacgag aagcatgtgc agctgatcca
      601 aatttttttg acggtattga ccttggtttt tgcgttcttc tacaccaagc atcatcagcc
      661 aaaatttcat ttgacgtcat ggacttggta ccttatatgt gggggggttc tgggcttttt
      721 agctagtttt ttaggtattg gtggtggacc agtcaatgtt tctttgttga tgctgatgtt
      781 tgcattgcca ataaaagaag caacactata ttctctatct acgattttct tttctcaact
      841 ggcaaaattg gtaacgattg ctttaacaag tagctttatg cgctttgatt tatctatgtt
      901 gttttatgtt atccccgctg ctgttattgg aggtttgtgg ggagcaagat ttagcagggt
      961 tttgtctcca aaaaaagtga cctttatttt tcaagtaatt gtcctcgtgg ttcttttgat
     1021 caatctttac aatgctttcg tcatcttaca aacattagga gaatctagac taacgcaagt
     1081 caaaatcact gaaacatatt gttctaaatg aaaaaaggag tatactgtga taaaaaaatt
     1141 catttaaaaa aataaaaatt ggctggtgat ttggatgttg cgggaaatgc gtttaggaga
     1201 tgcagaagca ctacgagaaa tcaatgcgga acaattagga tatgatgtac cattaaccgt
     1261 tacggtgaga caaatgaaga aactgttgaa ggagccagaa aaaaattttt tcttggtcta
     1321 tgaagatcct acttctaaaa aagcagctgg ctatgtacaa gcggagtcct atgaatcgat
     1381 tttcagcgat ccgatgttca atattatggc acttgctgtg tctaaacatg ctgaaaaaag
     1441 aggaatcgga aaggccttga tgactggcgt agaagaagcg aaaagacgag gaatatcagc
     1501 aataagactt aattctgcag aatacagagt agaagcacac cgattttatg aacgcatcgg
     1561 ttatcattcc gataaaatgc aaaaaagatt tttgaaaatc ctgtaaattt ttatcaaaaa
     1621 atacctggtc atcaagccga tacttgatga tcaggtattt tttttgacta agaaagtaat
     1681 tgcatcaaga aacctgagat gatcaaaacg atggcaccac caagccgatt gcccatttga
     1741 gcaaaagcaa taagttccat ccgattagct gcagataaga cagctacatt tcctgtacca
     1801 cccatcgagt tgttgcataa gccagcagta atagttgatt cgattggata taaaccaaac
     1861 aaacgaccga caaatcctga aactactgaa atcgcgataa cacttgtcaa acataagaca
     1921 acaaattgcc atgtcaaagc agaagccaat acatttagat tcaataacgc aataccgata
     1981 ccggcaagaa cagctgctgt caagtttttg acaatcaagt tgttgaacat gatagctgca
     2041 tcttcgtaat attctggtaa taggtttgcg attttacaga taacaacgat aatgatcatg
     2101 aatgcgtaag catggacttt aggaacaaaa tagttacaga tttgtcctaa gatgaagaaa
     2161 gtcaatgata ccatcaaacc gacacctaat tgtggaatgg aaggttttac atttctaggt
     2221 tttccatcgc caaggtcgcc tttttccatt aatttaccat taccgttgaa ttttggcatt
     2281 gattgtcccg cacgagcaac taacgctgca ccaatgatag ctaggacatt tgtcattgct
     2341 gtcgcaggaa tcaggcggga aatgatagaa gaagcgtccg tacctaaaac atttgcataa
     2401 atcgttgata aaggtacagc tccggctcca acaccaccag ccattgcggg caatgagata
     2461 tataaaacgg aatttgcaaa accatttccg ataagcatac ctacgagtcc tacggcaaaa
     2521 aaggagacga ccattgaaat aagtgcaacg ggaataaaac gaacagaagc tttcatcaat
     2581 agattacggt tcataccaag gatgctacca gtaatcaagg cagcaatata aaagtctaaa
     2641 aagcccatat tgctgacaaa gttttctgtg gattttacta catactcagg taagatccca
     2701 aatgtagcaa tcgcggcaga ggcaaagatc gcaaaaacgg agccaccacc taaataactt
     2761 ttgacgatag ggatttttgt tccgataaaa tgaaataaat taccgaaaat gaccaaaaca
     2821 gcgattgggc caatcatatt cgtcggtaat tttcctaaag ccattgcaat gatcaggaca
     2881 aggaccatga tcaaataaag gggcaaactt acgccggtaa tttttgttga ccaaaaccct
     2941 tcttttttct tttcctcaac tgcagttgcg gttgttgttt tttgtgccat ttttacagat
     3001 cctttcttat tctgtatcgt atgaaaaaag ccaaagagaa gcggcaaaag agcagtagtt
     3061 ggctggctgc tgttttgccg cagtcgcttt tttcttttta gacgtcatac aaagtttctg
     3121 tatgttcttt tactataaca atcttaatct tctaaagatt tatattcagg aacccattta
     3181 gcagattcaa cagcttcttt gatatccgtg atttcttcac gattcaattt ttgtgcaaca
     3241 actgattttg cgacagtttc agcaatcgtt tgagagaatt cagtgatttt tgctactgga
     3301 ggcaagatag ctgctcctgg ttttgttaca tcaacgattc cgcctaatgc tcgactagct
     3361 tgagaaatga tttcagcatt tactcgtgta gctgttgaag caatcaaacc aagccctaaa
     3421 cctgggtaca tcaacgcatt atttgcttga ccgatttggt aagttacacc gttatattcc
     3481 acatcagcag cagggatacc tgttccaact aaagcttttc cgtccgtcca ttcaatcaaa
     3541 tcttttgctt ttgcttctgc caattttgtt ggattagaca aaggcatgat gattggacgt
     3601 ggggtatgag ccgccatttc tttcacgatt tcttcagtga atgctccagg ttgggtagaa
     3661 gtaccgatca tgatcgttgg atggattgct tttacaactg cttctaagtt tgtcaattca
     3721 tcagcattag tgaattctga gcgtttacga gcgaatggga tttgaccagg agtcaatcct
     3781 tttgtatctt caaacaataa accctgttta tctacttgat agaaatgttg gcgtgcttct
     3841 tcttcaggta caccttgacg gatcatttca tctaaaagga tgtttgcgat acctacacca
     3901 gcagtaccag caccaaatgt caagatcgtt tgatctttca attgctcacc tgatatattc
     3961 aatccaccta atacaccagc tagtacaacg attcctgtgc cttggatatc atcattgaaa
     4021 gtagtgattt tatcttcgta tttttctaag atcgttgcag catttcctcg tccaaaatct
     4081 tcccaatgta ataacaattc tgggaataat tcagtagctg attgaacgaa ttgatcaatg
     4141 aattcgtagt aagtttcgcc ttctacacga gcatgacgat tccctaagta taatggatta
     4201 ttcaataatt cttcgttatt agtaccagcg tcgattgata caggcaagac ttgtgcagga
     4261 ttgataccag ccgcagcagt gtagaccatc aatttaccga tagcgatgtc aacaccgttc
     4321 acaccccagt cacccatacc taagattcct tctgcatctg tcacaacgat caaacgaatg
     4381 tcgcgtccat ctgctgcgtt tttcaaactt gctttgatat tttctggttc gtcgattgaa
     4441 agaaatgcag catcttgtgg tttcaagaaa atttcgttgt attgttcgat tgaatccgca
     4501 acgacaggat cataaacgac aggcatgaat tcaactaaat gttcgcccat caatttataa
     4561 aacaatgtcc ggttcgtatt gaatagattc attaagaaga tacgtttttc caaatcggtc
     4621 tgtttgctta agtattgacc gtaagcttgg acagattgtt gttccaatgt ttggacagta
     4681 cttggaagca taccagtgat tccgtatttt gcccgttctt cttttgtaaa agctgttcct
     4741 ttatttagaa aaggattatt taataagttt agccctgtaa gcatgaatga ttcctcctaa
     4801 gttttaatac aaacgaagta taggagtcag atgaggatat agtcaaaaag agcaggtata
     4861 ataaatttta tttatatgag taatagagtc aaaagaaatc aaaatagcgg tatttgttct
     4921 ttttatatca acaatccttg cttgattact atgcgtatct cttatatgct aaagaaagaa
     4981 aagtagaaga ataaaggata tgttagatag ataaatagaa tctctgaaga ataaatcacg
     5041 tgatcgtgac gataaaatac acttacgtca ggtgataaaa aatacataag tagaaaacta
     5101 agaggaggaa cagaaaatga aagaagttca attgatcaga aaaagcgaac tatcagaagg
     5161 tggttgcaat gcatgcggcg tagtagaagc aacaagctat acattaaagc ttggtgccaa
     5221 caaagcgata atctctgagt tgacagtagg cggtcttgtg gacagtctgg cgcttgctga
     5281 aggttttatt ggagaagata tttatgagat gttttcagaa atccgtcagt taaaaaaagg
     5341 ggaaaactgc atagaggttc atcatgagag cccgaatgtg agattcaaac gtggtgataa
     5401 tgagatgatc ttcaataatc atgtgtccga tcacaccgag ctatatggaa tcgtgaatca
     5461 aatactaact gagctttttg gattgggacc ttatgcgttc aaggaagaaa acggtaatcc
     5521 aaaattaaac gaagaatggc aagaaacgat tgaaatacaa agaaacaacc cgcacttatt
     5581 tcaataggca tccacagtat ttcgtaaaag ggactttgac acgacttttg tcaaagtccc
     5641 atcgtttttt atctatttgt gttctaaaca tttctttcag agtagtaaca actggaatga
     5701 ctgaaatgta aacagattat ttgcctgtat caatacggaa gagtaatata aagtgtgtaa
     5761 acgctatcat attattcatt caatttttta tagagggaag gcattgaaat ggaaaaaacg
     5821 tatcaagcag gtacaaatga aggaatagtg gattttatca atatggaaga tttagaaata
     5881 gccgcttcac aagtgattcc agctggtggt tatggttaca tcagcagtgg tgctggcgac
     5941 ttatttactt atcaagaaaa tgaacgggca ttcaatcatc agctgattat tcctcatgta
     6001 ttaaaagatg tagaattacc cgatacaact acacattttg acaaagaaac gctgactgca
     6061 ccaatcatca tggcaccagt tgctgctcat ggcttagctc atgtgaaggc ggagaaagct
     6121 tctgcaaaag gtgtagcaga ttttgggacg atctatacag caagttctta cgcttcttgt
     6181 acattagaag agataagaga agcaggcggg gagaaagcac cgcaatggtt tcaattttat
     6241 atgagcaaag atgatgggat caatttggat attcttgaag tggccaagcg taatggagca
     6301 aaagcaatcg tattgacagc ggatgcaaca gttggcggaa accgtgaaac agaccgcaga
     6361 aatgggttta ccttcccact gccaatgccg atcgttcagg cttatcaatc aggagtaggc
     6421 caaacgatgg atgctgtgta caaatcttcc aaacagaagc ttagtccaaa agatgtagaa
     6481 tttattgctg ctcattctga tttgccagtc tatgtgaaag gtgtccagtc agaagaagat
     6541 gtctatcgtt cattagaatc tggtgctggc ggaatctggg tatctaatca tggtggccgt
     6601 caactagatg gtggtccagc agcgtttgat tcgttgcaat atgtggcaga agcagtagat
     6661 aaacgtgtac caatcgtgtt tgacagcggt gtacgacgcg gacagcatgt tttcaaagca
     6721 atcgcatcag gtgcagatct tgttgctatt ggcagacccg ttatttatgg attgtcttta
     6781 ggaggaagta caggagtcca tcaagtgttt gatttcttta aaacagaatt ggaaatggtc
     6841 atgcaattag ctggaacaca aacagtagaa gatatcaaaa aaataaaatt gcgtgagaat
     6901 cgttttattt aagaaacaaa tgacgaaaaa aataggagtg cggcagatga tgccgtactc
     6961 ctatttttat agttcaagga tgtcactaat agaataattt gaaacgaaaa aataaaattg
     7021 aaatattttt tcatacttaa taaaaaagga agaatattca tgtaaacgat tttattgttt
     7081 ttttctcttt tatacaaaaa gggtcataat ttcaagtaag cggatgaatt catgaggatt
     7141 ttttgcatac tgtctctact atacttaggt cactaagaaa aaggagtgat ttattatgaa
     7201 aaagaacatg attgggacat tattactttc aacacttctt ctaggcggct tggcaacacc
     7261 agcttttgct gagggtcaag cgacttcaaa aggagatatt acctttactg aaccaacaaa
     7321 taccgtggag cctcttaacc ctactgatcc ttcaaaacca gtagagccag cagatccgga
     7381 aaatccagca actggccaga caggtccttt aacactggat gtagttcccg aattgccatt
     7441 tggtacacac gagattgaaa gcggaacaaa aacgtatcaa gtagacgctt caaaaaacga
     7501 tacaccttat ctccaagtat cagatcgtcg aggtgtaggt gcagatggcc aagcacaagg
     7561 gtggaacgtg acagtttcgg tttcagattt tgtaaacggt tcacaagttt tgcaaggcgc
     7621 tgaattagat tttggaacat ccactgttaa aagtacgtca gataacgaat ccactggacc
     7681 aactagtcaa actgtaactg ggttgagtaa agcaagtgca gcgacaccaa tatttacagc
     7741 agcaaaagat caaggtctgg gaacatggct ttctgtttat gatccagcaa atatcacact
     7801 gaaagtgccg aaagcagcag ctggaacatt cacggctgat ttgacttgga acctcgtggc
     7861 tggcccagta gcatagagta tgaaataaat tcaacaaact gcggtgaaaa tactataggt
     7921 gaaggatttt ttaccgcagt ttttgttgaa aggatgtggt ggacaatgaa tcaaagtaaa
     7981 cgactgtttg tttcgttttt ttctatttta agtctatttt tcatttttcc gtcaatcagc
     8041 caagcaaagg attcagcagg agactttgga atcaaaccgg tatttccaga gaaccaaata
     8101 gataaagcaa tcggttattt tgatttatta gtggcaccgg aacaaaatca gacactagaa
     8161 gtaattatca gcaattcttc agatgaagaa cgaacatttg aggtctctgt caatccggcg
     8221 gtaacgagtg atggtggaac gatcgattat agtcaaaaaa acccaacgtt agatgagaca
     8281 ttgccgtttg atgtccgtga cgttttgctc attgcgaaaa aggaaatcaa tgtatcagca
     8341 catgcagaaa caactgtacc tatagaagtg aaaatcccag caaaaagctt taagggacgt
     8401 gtattagcgg gtattcatgt ttcacctaaa gaagaagctg aaacagaaaa tgctacagaa
     8461 ggagcacaaa tcaaaaatcg tattgcttat aatctcgcag tcgttttaca agaaagtcaa
     8521 gagacgatag aaccggatct gaaactttta tcaggagatt tggacgaggt caacgcaaag
     8581 ccaactgttc agcttcgttt ccaaaatcct cagcctagga ttatcagcaa tttgatattt
     8641 acgagcaaga tcttttatga aaatcagctt tatattgaaa atacgtctaa tgcattttta
     8701 gttgcaccaa attcgaattt tcacttgaat cttgatttag ctggtgataa agcaaaagcc
     8761 ggcgattacc gcgcagaaat catagcaaaa tcaggcgaca gtaatgaatg gcgatttaca
     8821 caaaacttta cgatcaaaaa agaaaaagca caaaaagtaa atgaaaattc cgtttttgca
     8881 gtacaagaac aatctttccc atggctttat gcaggattgg ttgctgcagt tctagtgtta
     8941 tggttgattt tgctgttttt gtgggtccac aagaaaaaga aaaaaggaga aacaacatga
     9001 tgaggtgatt tcgttgaaaa catcgatctt attgggaggg attattgcaa gtttgctgtt
     9061 cttcagctgg caagagccag tccaagcaga taccaaaagt tcaggtacga ttacatttta
     9121 tgatctaagt ccaattccgc atccaagtgg ttcagtcaat ggcgcatcaa aacagcagac
     9181 acagctaccg atttataaag aatctaatca acatggcgta ttcccggaga cgaatgaaca
     9241 aaagatccgt tttctttatt tgatcattgg tatagaatta tggcttcttg cgtggttgtt
     9301 gttatggaga agaaaggaaa aggaggatga acatgttgct acaaaataaa ttttcatttt
     9361 ttcgctcctt cttttttact tcgctttttg ttttaagtat atttatcttt tcaccttcgg
     9421 cagaagctgt tggagcaacg cctcctgcca tttcttatga tccatacacg tatgaaaata
     9481 tcgtacctcc aaatggtgga cgtagtgcag tcaatggcgg gaagcttgtc caactaactg
     9541 gggctaacca attgcctaaa ttgactgcta cttatttgaa cgatggttca aatgatcctt
     9601 ggaaaggtgg cacggtccgt tttcattggg aaagccatgt gaaactaaca aatgtacttg
     9661 atttggtgaa tatcactgca caaggatttg catttgtggc gatcatcaat ttgccggaac
     9721 atgtatcaag cagtgatgta ttaaaagcaa ttgactggaa caacgcctac ttgtatattg
     9781 ccggtgcccc catcaaggtt actagcggaa gtttattatc agcaggaagc cataccttgc
     9841 gttttgggat ggggtcgtgg gatacaaata ctctattgac agatattatt gctattatta
     9901 cgcgaggcga attcaacgtg gacgatatcc cgcttcaatt tgatgttaca gctaatgtcg
     9961 cgaagatgac agaaaacgga gataaatatg atacgagtcc aaacaaaatt ttgaccaagg
    10021 gtaaattaca accttctatg tctaaaaagg ccgttttttc tgttgatttt tatgattcga
    10081 ataatattat ccaagatcgt atgttcaatt cgattttagc tccagctgca ggtagatttt
    10141 atcctaaatt aactggcgga aacttgaatc caggagcata tgcattttct gcaagtgcag
    10201 agataaatac gtggaatagt tacatctcac caagtgattc aacaggaaaa tataatacat
    10261 ttgctgatac cacagaatac gtggatggaa ataaccagaa ccttccaggc tctaccaata
    10321 gtcggacatt gacgatgggg ctgactgaag gacgttttga tcagttgcca tttagtcgct
    10381 ttgatcgcgt agtcaactat tttacaggaa aaaacgttac acaaggagca atactgactc
    10441 atactccagc aagcacaagt ggattgaatc agacagccaa tatcgtgtac agtgggaaag
    10501 atgcgcaagg cggattgctt tctcctgttg ctttaaaggt attggagcag tacaagctag
    10561 acggaacggt tttaccaaca aacttaacag ccgatagtca gtggggaaag ctcctttctt
    10621 ctgcatcgta ccaagtcacg gccaattggt cagcaactga actaaaaaag ggttcgatcc
    10681 attacaggct ttattcgaaa ggaacccaaa aattagcgac aggatggaca gatcaacttt
    10741 tccaaacgat ccaatcaaat aacgggggtg taaatacagc tacttctaca ctacctgcat
    10801 tggcttcagg gcaatattat tttgattatc gcttggtgga cgatgtactt actaacatgt
    10861 atccgtcttt tgcgtacaaa tggcagtctg aacaagctgg aatcaccact cttcctcaaa
    10921 taacagtggc taattttcca tctgtgagtg cagatagtca gctaaaaaac cttagcagac
    10981 aacctgagac aggagatccc ctgtctgctc tatcaggaga tacgattcaa gaaaatgtga
    11041 cattcacgtt aacaaaatct ggggatgcga taaccgacaa aaaaatcacg atctcacttc
    11101 ctgaaaatac tacttatatc aatggttcct taaaattaaa tggtacaact atcgcagata
    11161 ccggcattca acaaggagtt tctgtcccag cagatctatt gagcaaaata ggagatacca
    11221 ttcatcttac ttacaactat caattaaata ctgtagatac ttctttacaa tccgtcagca
    11281 tactgacaaa ggcagctgta ctttccagca atattacatt agcagatggt gctaagcttc
    11341 ctaacccagt tgtccaaaca tctgctaaaa caattcttgt ccccaaacaa gaattaacat
    11401 tagttaatgt accagatgat tttacatttg gtaacgatct ccccaaaccg ttgaagacaa
    11461 gttattatga atcaaaaggc gatttttctt ttgatgtgcg ggatactcgg cttccaagca
    11521 cgtctccttg gcaactgaca ggtacattga cttctttatt taagaatgat caaggtcaag
    11581 aattaagcgg aacaaaatta tacttcaatc attctggatc aaagcaattg attcagcaag
    11641 gtcaaaacac gttgatttat gagagtgatg gaacagctaa aggagaggtt ctcgttgact
    11701 ttcccgatac cgatggttta ctcttagagg taaatagcag tacgaatgct caacctggcg
    11761 caacgtatca aggcatggtc acatggaaac tgacagctgg gccaaccagc taagtgatta
    11821 gaatttgtat ggatctgtga taactgtcac agatcctctt tttcaaggat gagaaggaaa
    11881 cttctgctgt taaaatcaga aatgcttgaa ggagtggact tggaactttt cagtttgctt
    11941 gaaaaaaatg aacaacggca aatcaaactt ttccaacttt tattagagga aaaaggagag
    12001 gtttccgtta ataacgtact tacccgctta tcagttgatc gggctacctt gaaagaagat
    12061 ctgttttatt tacaagctaa cttggaaaat atcaaacaat tggaaattgt tatccaagaa
    12121 gggaatattt tattaatcag acatggaaat atagcagcag tcgatgttta ttatcattgt
    12181 tacttgcgct attctacaaa atatcagata cttctttatc tgttggaaaa tggctcattt
    12241 gatcggcaga aacttgtcat ggaacttaat atcagttcgg ctactttgtc tcgcagagtg
    12301 aaggaattaa atgattcttt aaatgagttt catctgaaaa taaaaagcgg gcggctgacc
    12361 ggtccagaaa gtcaaattcg ttatttttat ttccaattat tttggtttgg acgtccctat
    12421 cttgaaaaca aaaaagaata cagtgattta tcaggaaaca cttttttaga tctgctgcaa
    12481 aaagagttta gttttgctat tacagaagaa ggacgattga aatttgaaat atggctttcc
    12541 attatgaaga agcgaatgcg ctgtacgaaa aaatccaaac cagattatag caatcttcct
    12601 gttggattgt ttcaaacgac acaattttta ttggacctcc atacattttt gacccgttac
    12661 ttctttcaat atgcctttcc ttggaatcaa aatgaaacgt tggtttttta tcttttcatg
    12721 atcagtaact ttacattaga tacacataac tcgcatgtcc aggagttttt gataagcgaa
    12781 aaatacaaag acgacgtagt agctcaattg aatcgaacgt ttaaacaatc gatagaagaa
    12841 tatttctctt tttatgtttt tccagaagag atttcgcaaa agattgcgtt gacagtgatg
    12901 caaaatcacg ctcattttgc ctattttaga ggatggatga atatttttgg ccaagaagga
    12961 ttaaaacagc ggttaactga agtagaagat aaacaattcc tggttttatg tgaaagattg
    13021 gtcagacaaa catttgctat tgttgatttt actgaagtag acgaggaaaa tgcccgcttt
    13081 gaattatttg ctcgctatgc atctatttta cggacgctga tcaagcagtt agaattacgt
    13141 ctgcaaattg cttatgatct tccttatgaa aggctaatgg cggatatcgt gaaagaaatc
    13201 atccaggaac aattgctgaa tacgatcaaa tatgatttag tcgaatacga gaaagaaaag
    13261 cagtatgata tcattttgac tagccaattg aaagagtacc cgtcacagaa gtccgctaaa
    13321 gtttttgtat tcactagcaa cgaatataat tatgatttcc cctatttgaa ccaattttta
    13381 aaagaatgtt atttagaaaa attgaattta aggatgaata aaacatgaaa atcgtgatca
    13441 ttggtgcttc ccatgcaggc atcacagctg ccctaaatct aagaaaactt caaccgaaag
    13501 cagaagtttt actgatcgat gaagatcata aagatggact aggctatgtt tcaaatggaa
    13561 tcaaccttta tttaaaagga aagatacgta gtttagctga agttgcccat aacatgcgga
    13621 ctcttcaaga aagtggggca aaactgatca ccgaatggag agtaactgaa cttgatccag
    13681 acaaacatca gctcatcctc gcatccaaag aaggaaaaaa cgagaccata acctatgata
    13741 aattaatcgt agcgacaggt tcctctcctg tcaccttgta taaacaaatt gaagctgaaa
    13801 atgtctacac ctataaaaat ctagtgcaat ctaagcaagt acttgccgct ttaaaagaag
    13861 caaaagaagt agtgatcttc ggtgctggtt acattggatt ggaattagca gatgctttga
    13921 gaaataaagg atacattatt catctagttg attatatgcc gaatgtttta tcaagatatt
    13981 tcgataagga tatgatcaac agttttcaaa atcagctgca aactaagcaa ataaattttt
    14041 atccaaatga attcttgatc gattggaaaa aatcagaaga gaaagtagta tccgtacaac
    14101 ttctgtctca aacaataaag gcagatatgg tcattttttc tgcccaaact cgtcctaata
    14161 cgacattgtt aaaagaaaaa gtggctttgt atgaggatga gactgtgata gtcaatgaat
    14221 atctgcagac aagtgatccg gacatctatg cgattggaga tatcgtccca gtcagttttg
    14281 acaaaaataa acggcatctc tttttacctt tagttactcg agctgtacat atggcaagag
    14341 cagtagcgct aactttgagt ggtcagccaa ccgcttacga cctcagacaa aagataacag
    14401 cagcagtcat tatagactac tttttaggaa ctgtagggct gacagaagat gaagcgccat
    14461 tcttggaaca aaataccggt tcgtgttcag gagaatttga tctatttcca caatacgacg
    14521 aagaaaacaa aacagtaaat gcaaagctga tctaccatcc ggatacatta gaaataattg
    14581 gcggacagct gataagccaa gaattcttat tatcagattt gaacctgctt gcggatatcg
    14641 tgaaacacaa aactacgatt ccacagctag cagttgagga ttttggattt ctgtctgaat
    14701 acacctctcg ttttcactac ctcaatgagt tagcttttaa agtactagct aagagagcaa
    14761 atagcaatag agtagataaa agactgtgag aaatatcacg gtcttttatt gtgtggggat
    14821 ataataaata ttaatcaatc gagaataaaa aattcatata atgaaatagc ggaagaattt
    14881 tttgagcata atattcgcca aaaatttatc aagtgataaa attgttgtat aaaatgatta
    14941 tttcaggagg aggagttaaa tgtttttagc attaaatgaa attatgcatt caaagttacg
    15001 ttatgcgtta gttgcagggg tgatgttttt gatcgcctac ctggtatttt ttttgactgg
    15061 gttagcttat ggcttagctc aagataatcg aacagcagtc gacaagtggg aggcagattc
    15121 gattgtgctt tcgaaagatg caaattcaaa tctagggatg tccatgatta ctaagaagat
    15181 agcagaagaa gtcgaaggtg ggaaagtggc gtatcttgcc caaacacctg gagtcgtgac
    15241 tagtaaagac agtacagaag aaggaaaaat caatgttagc ttcttcggta tcgataaaaa
    15301 tcaattcatc atgcccaatc ttgttgaagg aaaagctttt gataacgatg atgaggcagt
    15361 aggcgatatt agtttgaaag aagaatatgg tctagccata ggagatacag ttaagttatc
    15421 tggtagtgac aagacgttta aactaactgg ctttacggat catgccaaat tcaatgtctc
    15481 accagttctc tatacaacca tcaatgctta ccaagaaatc cgcttcgaaa aagaagatac
    15541 aagtgaaaat gcacggatta acgcaatagt tgtcagaggt aaaatcagta atttacctga
    15601 agatttagaa cagatcaaaa tttctaaatt catcaatgaa ttacctggat ataatgcgca
    15661 agtattgact tttggattta tgatcggatt tttgatcgtt attgcggcta ttgtgatcgg
    15721 gattttcatt tatgtactga cgatgcaaaa gattaatatc tttggtgtaa tgaaagcaca
    15781 agggatcaca ggaggattta ttgcgcgttc tgtagtggca caaacattca ttttatcatt
    15841 tgttggtatt cttcttggtc tattaggaac agtgggaaca tcccttgttc tacctgatgc
    15901 ggttccattc caaagcaatt ggctgttttt tggcgtcatt agcttgttga tgttagtagt
    15961 agctgtgtta ggcgcactat tttctgttcg gacaatcgta aaaatcgatc cgttgaaggc
    16021 aattggataa gaaggaggaa gaacatgaaa gcaatagaat ttaaagaagt agaaaaaagt
    16081 ttccaagatg gcgaccaagt agttaaagca ttgaaagaaa caaccatgag tatcgataaa
    16141 ggggaatttg ttgcaatcat cggtccttct ggttcaggta aaagtacttt tttgactttg
    16201 gcaggcggat tgcagacgcc tagcagtggc tctgtattta tcaatgatca agaattcagt
    16261 aatcaaaaag aaagcgaacg cgttaaacta cgttttaaag aaattggctt tattttgcaa
    16321 gcttccaatc tggttccttt tctgacagta aaaaagcagt tattattagt agataagatt
    16381 aaacatgaac atcgtcaaaa agaagcaaac gaattatttg agcagcttgg cgtggataag
    16441 ttgatcaaca agtatccaga agaactatct ggtggagaac ggcaaagggt cgcaatcgct
    16501 cgtgcattgt acaatgatcc gtccattatt ctagcagatg aaccaactgc tagtttggat
    16561 tcagaaaagg cacgagaagt agtcgatatc ttggcaaaag aatcaaaaga caaaaataaa
    16621 gcaacgatca tggttactca cgatacacgg ctgattgaca aatgcgatag aatatttatg
    16681 atggaagatg gtgtattgaa agaaaaagaa taaccaaaaa gcaggtggaa aaatggtcca
    16741 tcgatacaac aaagatacac agcaaaaaat tttgaaagaa gcgactgact tgtttatgtc
    16801 caagggatat ctcggcactt caacaagaga aatcgcacaa aaagttggga tcacccagcc
    16861 caatctctat cattatttcg gtgataaaga aaaactatat acggcagttt tagaaaacca
    16921 cttaaaagat gttggaaaag ctttgagaga aatcgttcaa acaagcgaaa cgggatttca
    16981 agtaaccttg acaaaaatgg cgcagttttt gattgagaca catctggtcg atttgtttct
    17041 gatgcttcac gatcttgaaa gcaatctttc aaaggaaaca agagatcatc ttttctttct
    17101 atggaagaaa aattatcgtg aaccttttga agaaatcttt tcagcaaacc aatctgtgct
    17161 aagaaatggg atttcaaaag aaatcgcagc aaggcatttt ttcttagtgt tagcacctta
    17221 catcactcgg tcgaaaagac ctgtggaaga accgctaaat gtggcgcaat tgatcgattt
    17281 atatttgaat ggtgtattag gagaagcgta aagctgttat atagggagaa aatagttagg
    17341 tgaagaagca agatatgacg aagatcgtta tatcttgctt ctttatatag gtagtttttc
    17401 ataaagacaa atttgttatt ctctcatgat tatcagggta tatttttatt tattatgtcg
    17461 gtgttccagg aagtgtttta atttaataac gaagaaatta attgtttgta gaatgaagga
    17521 aactatttat tgggtagatg aatcaccacg aatagtcaaa aggagatttc aggatatgcc
    17581 aaaaatgaaa aaaatcattt tagcagtaat gttattttct acggttatat cttttacagc
    17641 cccttttttg cttacttaag ctgattttaa gttttggccc ttagtctgga tctacgaggt
    17701 gagagtcaag aatgaaaaaa ataattggag cttttgtatt tgcaatcatt atcattatta
    17761 tctgttttca aatagatgtt tttggtcaaa aaaagatagt tggacaaacg gtcagcagta
    17821 cgaacagtac ggttacaaag acaaaggaat catttgatga tacagaacaa gagacattaa
    17881 tcaaaatcgg aaaaaatgac cgtacactat atacagatga ctcgctaact accccacttg
    17941 caactataaa cggcggagag ctggcggagt ttctttctga aacaaaaaat gcttatcaga
    18001 tcaagacaaa tgatggctat actggatatt tagccctcga agatggaacc aaagtcacaa
    18061 agaatataca aacaaaaccg gaagagctat ctgatgcagt gattgtatta gatcctgggc
    18121 atggcggaaa tgatactggg gcattaagca atgatgaaca aacagaagaa aaagatataa
    18181 cattaagtac agccataaaa gtaaaaaagg cgctagagga tgctggagca acggtttatt
    18241 tgacccatac tacagatgaa ttagtacagc ttggagatat atgcgactac agtgaagaaa
    18301 aaaaggcaga tgtctttatc agtttacacg cagactctac ggaatatgcg aatgaagcaa
    18361 ctggaatcac gacatattat tactatggac aagaggaaac attagcacag acaattgctg
    18421 actccttcac tgatctgcct ctggattcaa gaggaatctc cactgggaac tatcaagttc
    18481 ttcgagaaaa tcttcaacct tctattttaa tcgagatggg ttatatgaat aatgatagtg
    18541 atttaaagga attagtaaca gacagttatc agcagcagat tgctgcaagt ttgacacaag
    18601 cattgaccac ttattttcag taataaataa gcccagccaa acaaaaatag ctcctcatat
    18661 ttttcgtttg gccgggctta ttatcgcaga tgcaagcttt tgaacaccgt ttattttttt
    18721 agtagcttca aagctttttc tgtatttgca aagtgaagtt tggcatattt ttcaagcata
    18781 ggcatgccgc ctttctccaa tagttttgcc gctacttggt cagatttcgt tccagctcct
    18841 gatggaaggg tgattccagc ttcagctgat gctttgtgta actcttccaa aaagctggca
    18901 cgactgatga tagaagcagc agcaacagct aaatgatatt gttctccttt agtaacgaag
    18961 tacagttttt cttgtaattg atttttttct aaacgcgcat attttttaaa atttgcttcc
    19021 ggcgtaaact gatcgatcaa aatcgcttct ggtttttctg gctcgatttt ttttagcagc
    19081 aaatggatcg cttgattgtg caaagcgact ttcatccgaa cggcattgta ttttggttgg
    19141 atctcattgt atttttctgg agataagaca agcagtttat aggggatggt tttttttaag
    19201 atgtcagcaa gctggatgat ttggctatct tttaactctt ttgaatctct aacaccaagt
    19261 ttacgtaatt ctgcaagctg atcacgtttc acataagcag cacatactgt tagcggaccg
    19321 aaatagctgc catttccgac ctcatcacta cctaaaacgg ataattgact gatatttttt
    19381 ggcaaagaag aggctgtttt tgctggcttg gcttgtttat cctgtgcctc cccccattta
    19441 tcagcttcta ttgctgcatt cgtaccttga aacatcactt ttccggatgt ataagcggta
    19501 atggtcgtcc cgtctttttt tgcagcaaag ctagtataag gaatctgttt atttaacaaa
    19561 taagagcgat agtatgcttt catttgacta agttggtcgt ttgttgcttt gataatgacg
    19621 ttgctcataa aattctcctc gtttttatac ataaaactat accgcaactc acgacttttc
    19681 gttttctaag agattgcgag acatagcatt tttttaaagt ttatcatata atagttaagt
    19741 atgtgaaaaa tatttgtgga gaacggtgaa agaaccaact tcatggtaca ctaaataaaa
    19801 ctttcatcaa ataggaggaa atgattcgta tggcgcacga aaaaacacgc tacaaagcgg
    19861 tgattgccaa ccaaacatat actattatcg gacgggaaac caagcatcat atggatatcg
    19921 taacgaagct gatcaatgaa cagttagcag aattgaaaca attatcacca caaatggata
    19981 atgaacaagc agcaatcttg atggctgtca atgcgctttc ggatcaattg aagaaacaag
    20041 aaagaatctt ggagctggaa gaagaaacag cagaattaaa gaaaaaaatg atcaaattta
    20101 cagagcttga aaatcgtgtg aaacgcattg aagcaatcga gaacgaagct cgggaagtat
    20161 tgaaagaaaa tggtcaagca gatcatacca ttaaaaatca tgtggaagca caacagattt
    20221 taaacgagaa acgaaaagga caaattaaac aaaaatcttc taattaagat ccttttatca
    20281 aaataagaaa aatttaaaaa aagttagaag agaaaggaac gtagcatgct gagtttgctg
    20341 attttatttt tattgctaat tgcgtttttt tctggagcac gtcgcgggtt tgctttgcaa
    20401 atcatattcg cgattggata tgtattgtca tttattgctg cccagcattt ttacaaacca
    20461 ttagcaagtc atttggaatt atacattcca tacccagctg tcacgccaac atcaaagtta
    20521 gcattttttg atcaggtatt tgcctttcac ctagatgaag ctttttatgc aggaactgct
    20581 tttctgatta ttttgctaat tggctggctg cttacccgat ttgtgggggt ttttgtccat
    20641 ggattgacgt atgtgccgat cttgagacag gtagactgga ttgcaggagg catcctgtca
    20701 ctaatcatgg cttacgttac tatatttttg attttgcagt tacttgcctt tgttccatta
    20761 gatgtggtcc aaaatcaatt cggcgagcat agtttcgctc gctttatcgt tgagagaacg
    20821 ccatttctta ccaacaagat gtatgagctt tgggtaacga atattttgaa ttaaggaaaa
    20881 tagtgctgga aaatatttcg ttttttgtac agagtagatt atttaagaag gctgcgtagc
    20941 gtatgtccgg cacagctctt ttttcatagt gaaagataag gtgataaaat gaataaccga
    21001 atccttgaaa cattggaatt tgaaaaagtc aaacagatgg tcagacaatt tgtagtgact
    21061 gcacaaggaa aagaagaact ggcagaattg gtaccagtga gcgaggaaca aacgatcaca
    21121 aactggcttc aagaaactga ggatggattg aaagtgcaac gtctgcgagg cgggatccct
    21181 atacctaaac ttgaaaatat ccgtccccat atgaaacgga ttgagatcgg agcagacttg
    21241 aatggagtgg agcttgcaca agtttccaga gtattgtcta cgacaagcga attgaatcgt
    21301 ttcattgatg atctttatga cagtgaaatc gaatttgcac gtttgtatat gtgggcagat
    21361 cagttagtca cgatccctgt tttgagccgc cgtttaaagg aagcaatcga tgaagacgga
    21421 cgcgtgactg atgacgcttc tcctgagtta aagagcataa gacagaacat tcggcgaagt
    21481 gaacaagctg ttcgtgaaca gttagatggg atcgtccgtg ggaaaaatgc aaagtattta
    21541 agtgatgcga tcatcaccat gcgaaatgac cgctacgtta tcccagtcaa acaagaatac
    21601 cgcggtgtat ttggcggtgt agtccacgat caaagtgctt caggacagac tttatttatt
    21661 gaaccaaaac aagtggtgga tttgaataat cgtttgcgtc aataccaaat cgctgaacga
    21721 aatgagattc aacgtatttt aagtgaactt tctgctgaac ttgttcccca tcgtcaagaa
    21781 atcatccaca atgcttatgt gattggtaaa atggatctga tgaatgcaaa agcacgattt
    21841 ggtaaagaag taaaagctat cgtgccggga atcagtgaag acaatcatgt cgtcttgaaa
    21901 caagcaagac atccactgat cgatcaggaa aaagtagttt ctaatgacat cacaatcgga
    21961 aaagactatc aagccatcgt cattacagga cctaacacag gtgggaaaac gatcacgttg
    22021 aagactttag gtctgttaca actgatgggg caagcaggat taccgattcc tgcaggtgaa
    22081 gaaagtcaaa tcggtatttt tgaggaagta tttgcggata taggagacga acagtcgatt
    22141 gagcaaagtc tatcgacctt ttcttctcat atgacgaaca ctgtagatat tttatcaaaa
    22201 gtcaatgaaa aaagtctggt attatttgac gagctcggtg caggaacaga tccgcaagaa
    22261 ggtgctgctc tagcaatcgc aatcttagat gatcttggta aaaagtctgc ttatgtgatg
    22321 gcaacaacgc attatcctga attgaaagtt tatggatata atcgggcaaa tacgattaat
    22381 gccagcatgg agtttgatgt ggatacatta agtccaacgt atcgtttgct gattggcgtt
    22441 cctggacgaa gcaatgcgtt tgaaatctct agccgattag gtcttgatac agaagttatt
    22501 gatgaagcga agcagttgat gaatgatgag agccaagatt taaacgaaat gatcacagat
    22561 ttagagaatc gccggaaaat ggcagagacc gaatatctgg aaatgcgtca ttttgtttct
    22621 gaggcacaag aacttcacga tgatttgaaa gaagcttaca gctatttctt tgaagaacgt
    22681 gaaaaagaaa tggaaaaagc aaagaaaaaa gcaaatgaag tcgtgtcaga ggcggaagaa
    22741 aaagcagaaa aaatcattgc tgatattcgt aaaatgcaac agcagattgg gcaaggaaat
    22801 gtgaaagagc atcagttgat cgatgcaaag acccaattag caaatctaca tcaagaagaa
    22861 actttgaaga aaaataaagt attgaagaag gcgaaagaac aaaaaacgtt gaaaccggga
    22921 gacgaagtgt tggttacgac ttacggccaa agagggacgc ttttacgtaa aaacgggaat
    22981 cagtggcaag tagaaatcgg tatattaaaa atgaatgtgt ccgaagacga gctgacgcct
    23041 gttgctcctc aaaaagagcc gacacaacga gttatccatg ctgtacgatc tgaatctagt
    23101 agtcacgtgc cgaatcaatt ggaccttcga ggaaaacgat acgaagaagc gctaagtgag
    23161 gtagatcaat atttggattc tgccattcta gctggttatc ctcaagtgac tattgtccac
    23221 ggaaaaggaa caggcgcact tcgcaaggga attactgatt atcttaaaaa ccatcggagc
    23281 gtcaaaagct ttgagtttgc accggcaaac caaggcggaa atggtgcgac aattgttaaa
    23341 tttaagtaaa gcttactaaa ggtaagcaga tggttcgcta tccaagtata gaaatgctat
    23401 actagtcata gattttaaaa atggaggtct ttgatatgtc acaagtaatt acagataaga
    23461 catttaatga agaaacagat aaaggacttg tattgattga tttttgggca acttggtgtg
    23521 gtccatgtcg tatgcaagca ccgattttgg atcagttgga acaagaatat gatgaagaag
    23581 aattcagaat tgctaaaatg gatgtggatg aaaatccaga aactcctcaa caattcggta
    23641 tcatgagcat tccaacatta atgttgaaaa aagatggtca agtagtagaa aaagctgttg
    23701 gtgttcattc aaaagaacaa ctacgtcaaa tgatcgatca atatttataa aaacttacag
    23761 caaaaataag ctgagggtgg gactgaatcc agttccgtcc tcggtttttt tgcggttgag
    23821 ttaaggttat tcaaattaat attttttgag tataattacg ttgtcaggct ggattgtttt
    23881 tttgacagac atgctataat aactttaatt gaatatgaag gggagtacca gatgaacgaa
    23941 cgaatcaaaa acaaattagc tttacttcct gatcagcccg gctgttactt gatgaaagat
    24001 aaaaatggaa cgatcattta tgtcggcaaa gccaaaatat taaaaaatcg tgtccgctca
    24061 tattttactg gtagccataa tacgaaaacg gaacggcttg ttagtgaaat cgaagacttt
    24121 gaatacatcg ttacagaatc gaatatcgaa gcattgctct tagagatcaa tctgataaag
    24181 aaaaatgatc ctaaatacaa cattatgtta aaggatgata aaacctatcc tttccttaag
    24241 ataacgaatg aaaaatatcc ccgtttggtg attactcgta aggtactaaa agacaaagca
    24301 ctgtattttg gaccatatcc cgatgtcggt gcggcgaatg agacaaagaa gatcctcgat
    24361 cgattatttc ctctgagaaa atgcaaacct agtcagacga aggagccttg tctttactat
    24421 catttgggac aatgtctgtg tccttattat ttcgacgtag atccgaaagt ctatacgaaa
    24481 atcgttgatg aagtgaaaaa ctttttaaac ggaggacacg aaaaaatcga gtcagagatc
    24541 catcagaaaa tggaaaaagc tgctgaaaac atggagtttg aaaaagctgc agaataccga
    24601 gaccagatcc gtgccattga gacaatcatg actcgccaaa aaatgacaaa tactgattta
    24661 ctggatcgag atgtatttgg ttatgcgatt gataaaggat ggatgtgtgt ccaagtgttt
    24721 ttcgtaagac aaggaaagct aattgaacga gatgtttcaa tgtttccttt ctataacgaa
    24781 gcagaagaag atttcttgac ttacctcggt cagttttatc aggaaaatga gcatttcatt
    24841 cctaaagaag tcttgattcc tgatacgatc gacaagccca gtgtagaagc tttgttagct
    24901 acgaaagtgc tgcaaccaaa acgaggagaa aagaaaaaat tagttgaatt ggcgagtaag
    24961 aatgcctcag ttgctttgaa tgaacggttt gatctgattg ccagaaaaca ggaacggacg
    25021 atcggagcag ttgaacgttt aggaaacgcg atgaatatcc cgaccccaat acgtatcgag
    25081 tcttttgata actctaatat catggggacg aatcctgtgg ctgcgatggt cgtattcatt
    25141 gatggaaaac cggcaagaaa agaatatcgg aaatataaaa taaaaacagt caacggaccg
    25201 gatgattatg catcaatgag agaagtcatc tatcgcagat attcgcgagt gattcgcgaa
    25261 gggttgcctt tacctgattt gatcttgatc gatggaggaa aaggacaagt agatgtggca
    25321 aaagatgtct tagaaaatca attaggaatc gatattccta ttgctggcat ggcaaaaaac
    25381 gataaacata aaacaaatga gttgctattc ggtacagatt tggctgtagt accgcttgag
    25441 cgaaattcac cagagttttt cttactccag cgaatccaag atgaagtcca tcgattcgca
    25501 atcactttcc atcggcagct acgcagtaaa aacagttttg cttcccgatt agatgaaatt
    25561 gaagggttag gaccaaaacg aaaaaaaatg ctgcttaaag agttcaaatc gttgaaaaat
    25621 atcacagcag ccacgacaga agaattacaa gaaatcggac tgccgaaaaa tgtcgcacaa
    25681 aacgtatttg ataaattaca tcaggaatga ggaaagggca ctttacaaag aaagtaaagt
    25741 gtcctatcat tttatgtaca acaaaaagag cgtttacgtt ttgttggtaa ataataaatc
    25801 gcttacgtct ggtgtctaag gatatatgtg atttcttgaa gaaggagtga agaaatgtta
    25861 gaagtcaagg atcttgttaa aacttttggg aactacacag ctgtcgatca tgtctctttc
    25921 caaatccccg atggaaaaat catggggcta attggccaaa acggggctgg gaagacaacg
    25981 acttttcgtt tgatcttgga ttttttgaca caagaccaag gagaagtgtt atggaatggc
    26041 catcatcttg gggagaaaga ttatgatgtc atcggttatc ttccggagga acggggactt
    26101 tatccgaaag taacgattca agaccaactg ctttattttg cagaacttag agggaaatca
    26161 agaaaagaga ttgaaccaaa aatcgacttt tggatggaaa aatttcaggt aaaagggaaa
    26221 aagacggata aagtaaaatc tttgtctaaa ggaaatcagc aaaaagtcca gctgatcgcc
    26281 acgttaatcc atgaacctaa attgatcatt ttggatgagc cattcagcgg gttagatccg
    26341 gtaaatgctg aattgctaaa agatggaata ttggaattga aaaaacatgg ttcatgtgtc
    26401 attttttcta gccacaatat ggataatgta gaaaaaatct gcgatcattt gatcatgttg
    26461 cgaaacggaa aaatggtttt gaatggaaaa gtacatgaga ttcgtgaatc atttggccgt
    26521 acgaagttat tcttggaatc tggtttaagc caacaggaag tagaagaaat cgaaggcgtg
    26581 aaaaaagtga tccttcatga agacaatacg ttagagatta ccttagaaga tcctgaagct
    26641 gggaaagaaa tctttactcg tgcgactcag ttcggctaca ttcctatgtt taaccagcaa
    26701 ccgccaactt tggaagagat tttcaaattg aaagcaggtg aaatcgatgc gtaagttttg
    26761 gattattacc aaagatgtct atttaaaaaa tgttaagtcg atttctttct tgatcatgat
    26821 attagtccct tttatcatgc tgggtatcat ttatgtagca ggaaactttg ctcaacaaaa
    26881 tagtgatgtc aataaaatcg gcgtattggc tgataatgag caaatcagtc agcaaatgag
    26941 ccaagtcaaa acagatgatt ttgagttcaa agcagttgat tctgaagaaa aagcacaaaa
    27001 agagctttcg gaagaaaaaa tcgatgcgta tttagtagtc tcaactgaga atgataagat
    27061 aaatgggatg ctttatagcg aaaattcatt aggacaaagt acacaactac tgatacaaca
    27121 acaactgact ggcttgcaat cgatgcttcg agcgagtcaa ttaggcattt caccagaaga
    27181 agtagctagc ttgagccaac aagcaagttt gactcgacaa aaagtcaatt ttgattcaaa
    27241 aggaaaaatg acagtcggag aagataactc gacagtccaa tacgtcgtaa gttatgtagc
    27301 aacgattgtc ttgttcatta ttattttgac gtatgcgcag atcattgcac aagagatcgc
    27361 ttctgaaaaa ggcacgcgga tcatggaagt gatcctgtcc agtacgactg cacaaaagca
    27421 tttttacgga aaattaacag gtgttttact tgttgcatta acgcaaatgg cattatacgg
    27481 tattattttt ggtataggat acagtcaatt caaagatatg gaaatggtca aaaatatatt
    27541 agacggtatc tcattggata acttgattgg accattcttg tggtattctc ttctattcat
    27601 gatctttggc attttgattt tttctgtttt agcagcttta tgtggctctt tggtcaacaa
    27661 agcagaagat acagcaaaag caattttgcc agtgacttat ctatctctag gcggatacat
    27721 gcttggattg atactaggag cttcagatcc aaacaatatc gttattcgga tcacttcgta
    27781 tattccattc ttatcttcat atattatgcc ggttcgctta gcaaatgaga cagtcggtat
    27841 gggtggagca ttgatttcct tgttggtact tgtagccgta acattcttat tgatgatctt
    27901 gtctgcaaac atgtacaaat cgaatgtact cgtttatagc gaaggcggat tatggagttc
    27961 attgaaacaa tcgatttcaa ttatgaggaa tgaacgaaaa aaagcataaa acaatcctaa
    28021 aatacagaag gaagctggac atctattgtt cccagcttct ttttgtatag acctatttta
    28081 tttattttac tatattggat atatattcat tgaaaatagt gtataacaac tttataatat
    28141 tgagtatacc aatttttgga ggcgttttaa tggaccgtta tttagattta ctttcagaaa
    28201 aattcccctc aacggaggat gtcatcacgg aaatcatcaa tctcgaagca attttgcagc
    28261 ttccaaaagg aacagagtta tttttgagtg atatacatgg cgaatttcct gcttttgatc
    28321 atattctgcg tatcggttca ggaaatctta aagaaaagat caaagacctt ttttctgaac
    28381 aaatgacgga aacggatatc agccaattca ctatttttac ggcttatcca gaatatgcat
    28441 taacgactga ttggtacaaa gaacaagata aatcgcagct gatccatcat ttgatcgatc
    28501 ttttacggtt tacgacagtc aaatataccc ggtcaaaagt tcgaaaagga ttgccgaaag
    28561 aatatagcta tatcattgag gaactcttgt atatcgatga ccgtatcaat ggaaaaaaag
    28621 actatgtaaa aaaaatcatt gaacaacttg ttttgatgaa ggaagaagaa aaatttttaa
    28681 cgaaacttgc acagacgatc caaaaatctg tcatcgatca tttgcatatc gttggagata
    28741 tttttgaccg aggaactcaa gcagccaaag tgatggatcg aatcatggat ttttcttctg
    28801 tagatatcca atggggaaat catgatattt tgtggattgg tgcgtattgc ggctctgagg
    28861 catgtttact gacactttta cggattgcag cacgctataa ttatttattt gaattagaga
    28921 aagaatatgg gttgaattta cgtccattgt tttcttttgc tcatcaaact tatcagaaga
    28981 atccagtatt tgcgcctaaa aacagtaaaa atctatccga aagagagcaa gaagaattag
    29041 aaaaaatcca tcaggcactt tctatccttc aattcaaatc agaacatcag ttattggatc
    29101 gtcgacctga atttaaaatg gacgatcgta aattgctgga aaaaatcgac tatgaagcat
    29161 caacgattga tttagaaggt cagctctatg agttgaaagg aacttgtttt caaacgatcc
    29221 agccagatga tccaaaaaaa ttcttggaag aggaacaaaa agtgattgat agtttgatgt
    29281 attcattcca gcactctttg agaatgcaaa aacatatgac gtttttgatc gaaaaagggg
    29341 gaatgtatct cacgaacaat cagcatgtgc tgtttcatgg ctgtatacct gtagacgaga
    29401 agggacagct cttagcattt gaattagacc aatcttatcg cggaaaagaa ctgctgggct
    29461 tttttgaaaa acagataact gaaagcgcaa aagatctgac tgcaaaagaa gatttagcaa
    29521 ccgatttgat ttggtatgcg tggagtgggc cattttcgcc tttattcggc aagagtaaaa
    29581 tggcgacttt tgaacgttat tttctcacag agcctcatac gcacgtcgag aaaagcaatc
    29641 cttattatca cttgcgagat gaagagtggt tcagtgaaaa aattttagca gaattcgaca
    29701 caaaagaaga agggtcagca atcattaatg ggcacacgcc agtaaaagta aaaaaagggg
    29761 agtcaccgat caaagcaaat ggaaaagtat ttgtcattga cggaggttta tccaaagctt
    29821 atcaaaaaac gacaggaatt gccggttatt cactattatg caattcttat ggtttccaaa
    29881 tcgtgacaca ttatccgttt ttgcctattg aacaacaatt tgcaaaaaaa tccgaccaaa
    29941 caaatgtgaa aaaagtaatc gaacagcaac taccacgcaa actcaatcgt gatacaacaa
    30001 aaggtatgga actgcagcag cagattaccc agctcaaaag gctgttggac tatcgaaagg
    30061 acgattgaga agaattccag tgaacattgt tccatagact ggagactgag acaaaagtcg
    30121 tgtcgcagtc tctttttccg gataaacggt gttcttctgc caactcctcg gtcacaagtc
    30181 acactattca acaaacatga aaagctgttt tttgaaattg ctccttgtga ctcagagttg
    30241 aacggcaggc tcacgacctc ttggtataaa cggtgttcaa aagccagttt ctcggtatta
    30301 agccaaattt atgcaaaaat gtgaaaagcc attttcacaa aatttttctt aatactcgaa
    30361 actaaacagc tttttcacaa ccccctcaga aagtctatta aaattcattc acaaagaaat
    30421 cgaataagcg ctgttcagat ggatgtacac ggtgggtaag ttccggatgc cattgaacac
    30481 cgaggatttt atgcatatca tctttgcttt gaaccgcttc aatgagtcca tcgttagaaa
    30541 aagcgatggc ttttaataaa ggtgaaagat ctttgactgc ctgatgatgg taagaattca
    30601 caaaatatgg atcggggaga aggttgctta acaaactgtc tgaaacaatc ttgacttcgt
    30661 gagtcgtaaa ttgcggggca gtgggctgtt gttcatgttt tactgaccac tttggatata
    30721 atgaaagatc ttgataaagt gtaccttcca aaacgacatt caatagttgg agtccccggc
    30781 agactgcaaa aattggtttt ctttgtttca atgcttccaa gatcagtgcc tgttcaaatt
    30841 ggtctcgttg aatatttgtt tccgttagct ttggatgagg atcttccatg taaagttgtg
    30901 gactgacatc ttgaccacct gcaagaataa gtttgtcgat ttgtccaatc agttgaggag
    30961 ctgaatctgg agacatgact ggcagaataa gaggcaatcc ttgagcatct aaaactgcat
    31021 ccacgaatcc ttgcggtgta tagctcactt gatttccttg gaaagtatct gttgctcgaa
    31081 tcagttgatt tccggcaatg ccgatgattg gtttcatttg tattccccct aaagtagact
    31141 tattgtaaca aggatttaaa aaaaattaaa ctatgtaaga cttgccccta tacttatctg
    31201 ttcttgctgt gttactatct gtaaagagaa atttcgtgtg aaattcatga cgatagttga
    31261 aaatattgct taatttgtta taataaaaag taagcagaaa taaaaaggtt gggcgtaagc
    31321 ttcaaggatc tagttcttca aggggtgaga aggacatttt attgaagggg cctgcctata
    31381 ctaagttatc tttagaggta catactttca atgaaaaaag aaagcatgta cctctttttt
    31441 aaatcgaaag gaagtgaagc aagtgttaga agctttggaa caaatccgaa aagcagaaga
    31501 agaaaatgaa aagcgtgctc aaacactgcg gcagcagctg aagatctatg caacagaaaa
    31561 agagcaggaa ttggaaacga tccaaacaaa ctatcgacaa caactaaaac agttggtgga
    31621 agaaaaagaa caatttgaaa tacaagaatt agaaaaagaa aaaatgaaat tgaaagcaga
    31681 agcagacaag gtgcaagcaa ctttgaaaga tcaatatcaa aagcatcaga gtcaagcgat
    31741 cggtgcgatc attgaaaggg tgaaagaaac ttatggccgt cactaagatg gaaaaagtga
    31801 ccctcatttc agataaaaga aatcaggaga ggattttaca agcagtacaa ggaatccaaa
    31861 acgttgaaat ccgggatctg tatcaaaata gaacaaacaa ccagtgggtg gagaagtatt
    31921 ttccagatac cacgattatt gataaagaag caaaattaag cgctttaggt aatcggttga
    31981 aagacatcca agaagctatc caattcatac aacaccacgg cgatagccgt caaaagaaac
    32041 tccatttgaa acgtcaagaa ctttccttac aagatttgga agccaattat tccgaagaaa
    32101 atttcataaa taaattgaaa gaagtccttg atttaaaaga aaagtgggaa caactaactg
    32161 aagaacgtga tcgtttagaa gaagaggaag aatggcttct tcattggcaa cagctggata
    32221 ttgctccaag tatgtatgca agtaagacga ccatttttga gatggggact gtgagtgcag
    32281 caaattttga aagtttcaag gaagaactga gtaagcttga tgacgtttat atggaagaaa
    32341 tagattatac gccaaaacaa gtttatcttt cgtatgttgc tttaaaaaaa tcagttgctg
    32401 ttatagaaga aattgctggg aaatacgggt tcaataaaga aacgtatcct tatgaacaaa
    32461 atcctaaaga aaaactgcaa gagaccaagc agcaattatc cattgttcac gagcagcaaa
    32521 agaagataac gacagcgtta ggtcagtgca gtggctatat ccaagaattt gaatgggtag
    32581 aagaagtcac acttgccgtt gcagaacgag aaaaaataaa agaacggttt atccatgcga
    32641 cttatctgat cgttttgcaa ggttgggtag atgcagaaga aaaacagaat ttgctgcatg
    32701 tgttaaacga aaccgtatca gaagaagata tatacgtcag tttcgaaaca ccaaactcag
    32761 aagagattca gcaggaagtc cctactaaat tgaaaaacca tccgcttgtc gaaccttttg
    32821 aattgctgac tgaaatgtac agtctgccaa aatatgaaga agtagatcca acaccttgga
    32881 tgacaccatt ttatcttgtc ttcttcggga tgatggtcgc agatgttggt tatggtttgc
    32941 tgatgctcat tgggacaata ctagctcaaa aactacttgt tctaccacgc gggatgaaac
    33001 gtttcgtaaa attctttgag attctctcga taccatcgat catctgggga ttgatctaca
    33061 gttcattttt cggacagtca ttaccaaaag aactgtttgg catccgcttg cctttcccaa
    33121 tcctatctac gacggatgac gtcaatacga ttttgatttt atccgtgatt ttcggtctga
    33181 tacagatttt ggttggatta tttgtggcag caaaggaaaa tatcaggaga aaagattact
    33241 tgagtgctgt cagtgatgga tttgcctggc aagggatcct aattgggatc gttattgcgt
    33301 tggttggtgc catgttgata aaaaatacag catttgttta ccttggcgct gggctatcga
    33361 tcattgctgc cttatgtatc ttgatcgttc cgattatcca aacgccgtct aaagtcaaag
    33421 gtgctgccaa aggtgcgtat aatctttacg gactgaccgg ctatatcggt gatttagtca
    33481 gttatacacg tttgatggca ttgggtattt caggcggaag tattggagcg gcattcaata
    33541 tgctagttgc tttcatgccg ccagctgctc gattcagtgt agggatcctt ttgatcatcg
    33601 ctttacacgc actgaatatg tttttgacac tgctaagtgc ctatgtccat ggcgcacgat
    33661 tgcagtatgt cgaatttttt gggaagtttt atacaggagg cggacgtgcc tttgatccgc
    33721 tgaaaacggc ggaaaaatac gtcaacatca atcacaagaa aaaaaacaat aaataattgg
    33781 aggattttta tataatgatg gattacttaa ttagtcaaaa tggtggaatg gtatttgcgg
    33841 tattagcgat ggcaacagcg acgatttttt cagggatcgg ttcagctaaa ggtgttggaa
    33901 tgacaggtga ggcagcagca gcattgacaa caagtcaacc cgaaaaattc gggcaggctc
    33961 tgattctgca attgcttcca ggtacgcaag gtttgtatgg attcgttatt gcctttttga
    34021 tttttatcaa cttaggaaat gacatgtcag ttgtacaagg actgaacttt ctaggtgctt
    34081 ctctgccgat tgcttttaca ggcttgtttt caggtattgc ccaaggaaaa gtcgcagcgg
    34141 caggtattca aattttagcg aaaaaacctg aacatgctac aaaaggaatc atttttgctg
    34201 cgatggttga aacatacgcg attttaggtt tcgttatttc cttcctatta gtgttgaatg
    34261 cctaagcata aaggaggaaa agcagatgaa cgccattgaa aaaatcatct ctcagatgaa
    34321 cgaagcagca gagcaggaaa gagcggcgtt agaacaagaa gagcgaatga agatcgatca
    34381 aaactttgaa caaaaacgta cgcaagttga aacagaacat caaaaacaaa aagaaaaaca
    34441 aatcgaatta ctcgaaaaaa aataccgtca gctaaggaat cgccagcaag tagaagtacg
    34501 acaagaaaat ttgaatgcga agcaggaatt tttaagacga ttgtttgcag atgcggtaac
    34561 tgaaatggaa aattgggatg aatctgaaca aatccagttt atcaaaaatg cattgtattc
    34621 attacctttg acaggaaaag tagcattcat tgctggagaa aaatcagcag cctatctttc
    34681 tcagacgttg ttggatgaat ggaacaatga acttcccttt atgatggttt taagtgatga
    34741 aactgttgct gatcaagcgg gttttctgat aaacgatcaa ggagttcagt ataattttct
    34801 tttcagcagc cttgtacaag atatccaagg aacgatgagt tttgagattg ccaatcaatt
    34861 attcgaataa ggagggatca gtgtatggaa taccacgaac taaatccctt gattcgcgga
    34921 agagagcttg aacttttgtc caatgagaca tttgaacgga tgattcaaac aaattctgtc
    34981 gaagcacttg gtgaaatatt gaaatccacg atttacagtc catatattta tgacggatat
    35041 gaatatgact tcgaacagaa tcttttaaag gagcagagcc gtctatttcg ctggttaaag
    35101 gaatcagcac cggagcctga aatcgtttgg atctatacga tgcgttatac tttccataat
    35161 ctgaaggttt tgacaaaagc tgagatgaca aatcaaaatc tggaccattt gtatatcgac
    35221 gatggatttt attcattaga aaccttgaag gatgccattc atacgcaagt ttcaaatgaa
    35281 cttcctgaaa gcattatgga cagtatacga gaagtacgtg attattttga agagtctacc
    35341 attcttcagg gaattgacgt gatttatgat cgacagtttt tgacagagca gcgacggctt
    35401 gccgataagc taggatatca agaattgctg acagaagtca ttgcttttat tgacttgacc
    35461 aatatcacaa cgatggctcg aggaatattg cagaaaagaa catatgggtt catgacgacg
    35521 gtactttcca gctcgggaag tatcgaaaaa gaagtatttt tgaactttgt agataaagat
    35581 atggaagatt acacgaattt tctattagag acagattatg ctgattttct gcgccctgtc
    35641 atccgtgagg gaaatattga tctcgtaaag cttgaacagt tgaaagatga ttatctaagt
    35701 tcattgtatc aagaagcaca aacccaggct ttcggaccac tgccactact agcctttttg
    35761 aacgcaaaag aggtagaaag caaaaacctt cgtttactgg ttatcggcaa aagaagccat
    35821 ttcgaatcag aaacaatcag aaagcgggtg agacaagtct atgacgcata agatcggtgt
    35881 agttggcgac aaagattctg ttttgccatt caaattgttt ggctttgatg ttcgttatgg
    35941 tacaaccaag caaaccgttc gtcaggcaat tgaagaaatg gcaaagaatg agtatggcgt
    36001 gatttatgtc acagagcaat gtgcagcatt gagcccagaa acgatcgaac gttacaagga
    36061 acaaatgata cctgctatcg tattgattcc caatcatcaa ggatcattag ggatagggct
    36121 ggaagaaatt caaaaaaacg tagaaaaagc agtaggtcaa aatatcttat agtatgaaaa
    36181 ggagatagaa attttgcaaa ttggaaaaat cataaaagtc tccggacctc ttgtaatggc
    36241 tgagaacatg tctgatgcca gtatccaaga catgtgtcta gtgggagatc taggagttat
    36301 cggagaaatt atcgagatgc gtggcgatgt ggcgtctatt caagtatatg aagagacttc
    36361 tggaattggt ccaggcgaac cggttcgctc tactggtgaa gctttatctg ttgaattagg
    36421 accagggatc atttcacaaa tgtttgacgg aatccaacgg ccattagata cctttatgga
    36481 aatcacacaa agtaatttct tagggcgcgg agttcaattg cccgcattgg accatgagaa
    36541 aaaatggtgg ttcgaaccaa cagtagaagc cggagaaacg gtgagtgctg gagatgttat
    36601 cgggatcgta gaagaaacaa aagttataaa acataaaatc atggtgccaa atgggataaa
    36661 aggaacgatc aaaacaatcg aaaaaggttc attcactatt gatgaaacag tatgtgtcat
    36721 tgaaaccgaa aatggtgaca aaaatttgac gatgcttcaa aaatggccag taagacgtag
    36781 tcggccaatc aaagaaaaat taaacccgga tgcacccatg atcactggac agcgagtgat
    36841 tgatacattc ttcccagtga caaaaggagg agcagcagct gtacctggtc cttttggtgc
    36901 agggaaaaca gtcgttcagc atcaaattgc aaaatgggcc gatgtggaca tggttgtcta
    36961 tgtgggatgt ggcgagcgtg gaaatgagat gacggatgtt ttaaatgaat tccctgaatt
    37021 gattgaccct aatacaggag aatcgttgat ggaacgtacg gtattgattg ctaatacatc
    37081 aaacatgcca gtagcagctc gagaagcttc tatctatacg ggaatcacaa ttgcggaata
    37141 tttccgtgac atgggttatg acgttgctat catggcagac tccacttcac gatgggcaga
    37201 agcacttcgt gagatgagcg gacgtttgga agaaatgcct ggtgatgaag gttatccagc
    37261 ttatcttggt tcacggcttg cggaatacta tgaacgatct ggaagagtca ttgcattagg
    37321 atcagaaggt cgcgaaggaa gtataaccgc aatcagtgct gtatccccgt ctggagggga
    37381 tatttcggaa ccagtcacac aaaatacatt gcgggtcgta aaagtattct ggggtcttga
    37441 ttccagttta gcccaaaaaa gacattttcc ttcgatcgat tggatacaaa gctattctct
    37501 ttattcaaca gaagtaggga agtatatgga tcatatcctt caagctgact gggcatccat
    37561 ggtcaccgag ggcatgcgta ttttgcagga agaacagcag ctgaatgaaa tcgtgcgttt
    37621 ggtagggatt gattcccttt cagataatga ccgtctgaca ttagaagtgg caaaatccat
    37681 tcgtgaagat tatttgcagc aaaatgcttt tgatgatgtc gatacattca cttcaagaga
    37741 gaaacaattc aaaatgttga agatgatctt gacctttggt gaagaaggac gccgtgcgtt
    37801 gtcgttaggt gcttatttaa gtgagatcat ggacggtacc gtatcgattc gtgaaaggat
    37861 cggacgaagc aaatatatcc cggaaacaga attagaaaaa ctagatcaaa ttattggtga
    37921 aatcaagcaa acgatgcaaa cgatcgtttc agaaggaggc atgagcaatg attaaagaat
    37981 atcgtacgat cggtgaagtc gtcggtccat tgatggcggt tgaaaaagtt gctggtgtca
    38041 aatatgaaga attaatcgaa gtccgtatgc aaaatggcga gattcgtcgt ggacaagtat
    38101 tggaagtcca agaagataaa gcaatggtcc aaatattcga aggaacaagt ggtatcaatt
    38161 tacgtgactc ttctgtacga tttttaggcc atcctttaga actaggtgta tcggaagaca
    38221 tgatcggtcg agtattcgat ggtttgggac gaccgaaaga taacggacca gagatcctgc
    38281 ctgaaaagca tttggatatt aacggagaag taatcaatcc agtagctcgg gattatccag
    38341 atgagtttat ccaaacaggt atctctgcaa tcgatcattt gaatacatta gttcgtgggc
    38401 aaaaattacc agtattttct ggctctggtc ttcctcataa agaattagct gctcagatcg
    38461 cgcgacaagc aacggtactc gattcatcag atgatttcgc cgtagtcttt gctgctattg
    38521 gaatcacttt tgaagaagct gaatttttca tggaagattt tcgtcaaacg ggcgcaatcg
    38581 accgttctgt catgtttatg aatttagcaa acgaccctgc aatcgaacgt atcgctactc
    38641 ctcgtatggc tttgactgct gcagaatatc ttgcttatga aaagggaatg catgttttgg
    38701 ttatcatgac agacatgacc aactatgcag aggcattgcg agagatttct gcagcacggc
    38761 gagaagttcc aggaagaaga ggatatcctg ggtatcttta cacgaactta gctactttat
    38821 tcgaacgagc aggaagaatc cgcggactaa aaggatcggt tactcaaatt ccgattctaa
    38881 caatgccaga agacgataaa actcatccaa tccctgactt gactggttat attacagaag
    38941 gacagatcat cttgactaga gagctttaca agagtgggat tcagccacca attgatgtac
    39001 tcccgtctct ttcgcggtta aaagataagg gaactggacc cggaaagaca agagaagacc
    39061 atgcagctac gatgaatcag ctttttgcag cctatgcaca aggaaaacag gcaaaagaat
    39121 tagccgtagt tttaggtgaa tctgctttat ctgatgtaga caagatctat gcgaagtttg
    39181 ctgagcggtt tgaaaaagaa tatgtcaatc aaggattcta cacgaaccgt tcgattactg
    39241 aaacacttga tctagggtgg gaactgctat cgatgttgcc aagaaccgaa ttaaaacgaa
    39301 tcaaagacga catgctggac aaatatctgc cagaagggaa gtgagttctg atggcacgat
    39361 tgaatgtgaa tccgacccgc atggaattga ctcgattgaa aaaacagttg acaactgcca
    39421 caagagggca taaattatta aaagataagc aagatgaact gatgcgtcaa ttcatcctgt
    39481 tgattcgaaa gaacaaccag ctgcgtcaag aaatggaaga gtctatgaca gaagcaatgt
    39541 ctgattttgt attggcaaat gcttcgatca cggaaccttt catcgaagaa ttatttgttt
    39601 tgccggcgga aaacgttgat ttgtctatcg tagacaaaaa tatcatgagt gtaaaagtac
    39661 ctgtgatgaa ttttgaatat gatgaacagc tgacagacac acctttggaa tacgggtatt
    39721 tgaattccag tgccgaactg gatcggtcaa tcgatcggtt tactaccctg cttccaaaac
    39781 ttttggaact gacagaaatc gaaaaaactt gtcaactgat ggcgagtgaa atcgaaaaga
    39841 cacgtcggcg agtcaatgca ttagaatata tgacgatccc tcaattagaa gaaacgatct
    39901 attatattcg tatgaagctg gaagaaaacg agcgcgcaga agtaacaagg ttgatcaaag
    39961 taaaaaatat gggtaccact gactaagtgg tatctttttt taaaagagga aaacgatgat
    40021 taaacaaagc aaacaaataa agaaacgttt gccggctgtt cagcttctcg cattaggatt
    40081 ttttctcctg attttagttg gcggcggcct acttacccta ccatttttta gtaatagtgg
    40141 gcatgggaca aattttatcg atgcgctttt cactgcaact tctgctgtct gtgtaacggg
    40201 attgacaaca ttgaatacag cagagcattg gaacagtgct ggtcaatttt tgatcatgct
    40261 tttgattgag atcggcggtc ttggttttat gatggttccg attctatgct ttgcattgat
    40321 aaagaagaaa gtcagtctca gcacacgtat tatattaaaa gaagcgctga atctagaaga
    40381 agtatcaggt gtgatgaagc tcatgcttta catcctaaaa ttggcctttg tgatccaatt
    40441 gattggtacg gttgctttat cttttgtatt tgtgcctgaa tttggctggt tgaaaggtat
    40501 ctggtacagt ttgttccatg caatctctag tttttgtaat gcagggtttg atttgttagg
    40561 agacagttta gccaatcacc agcaaaatgt ttatttgatc atggtggtat ctgctttgat
    40621 catttctggt gggttaggct tcatcgtatg gcgtgattta ctggaatatc atcagaaaaa
    40681 gaagatgacg attcattcaa aaatcgcatt aaccgttaca ggtacccttt tattaggcgg
    40741 attcgttgtg ttctttttca cagagcgcaa tggggcaacg ctagtggaag ggaatatgtt
    40801 tcaacgattg gcaaacacct tttttatgag tgtgacacct agaacggctg gatattattc
    40861 agttgattac ctccatatga gccatgcagg tctgatttta acgatgtttt tgatgtacat
    40921 cggcggaaca tctgggtcga cggccggcgg attgaaaaca actacgttag gtgtgttgct
    40981 gatccagatg cgttcgatgt tgaaaggacg tacgagagcg gaagcatttg gccgtaccat
    41041 ccgacaaggc gcagtgttgc gggcacttac tttatttttt gttacgttga cgttgtgtgt
    41101 agtcgccatc atgattttat cggtgactga aacgatacct aaaacttctg gcatcgaata
    41161 tattgctttt gaggtcttct ctgcgtttgg tacagtaggt cttacgatgg gattgacgcc
    41221 agacttgact gcaataggga aattgatcat tatagcgctt atgtacattg gacgagttgg
    41281 tgtattgact gtggtcttct ctctgatgac aaaagcacaa agaacacaat caaaatacaa
    41341 atatccagaa gaaagtgtca tgattggata atttcatctt ctgacagaaa cctagtgatt
    41401 tagtaaaata agaaaataaa ataatttttc ttgcttcttg gatactttaa gtgcaaaatg
    41461 ttcgtttatt ttttgaggca ctacccgttg ttgaacctcg ggtagtgcct cttttttatt
    41521 gaaaggaatc aataagattt gattccttta tttatcaata ggttataatt catatttttt
    41581 tattttttct tttacgatac ttagtccaga agctaaaatt tcaaggttat tagaggatag
    41641 ggaaattcga acgaatgcat ctggttgcgt acgtgtagta aagcgtctgg aatgataaag
    41701 tcggataccg ttagcaagaa agtcattctc aattatctta gggtcaatct caggatcaac
    41761 tggaagaatt cgatagtaag ggacacgatt cgttggtttt tctactttga aaagagaatc
    41821 aaaaagctga ttggctcttt ttgtaagact taatttagtt tctaagatcc tatttgcttc
    41881 atttgaatgg aggatttgag tgatgacttc cacatctaat ccagaagttt tcacatttat
    41941 attaaaaatt gcttgttcta tcttgctttg gacatgtact ggaactacaa gataagcaac
    42001 tcgcaatcca gaacaaataa attttgtcat tccagctaag tagattgttt ggttaggtaa
    42061 taaattttgg aaaggaggaa tgatcgtatg ttgatagtaa gttgttaaaa atgaatggat
    42121 atcatcttca ataacccata gaccttcttt ttcaatcact tcggctaatt gctctcgtct
    42181 tttgtgagag atttgaaacc ctataggatt attacaagaa ggcataagaa agacaccatg
    42241 aatcttcttt tttctacatt cctgaatcaa tatatcaggt cgcattcctt gctcgtcaaa
    42301 atcaattgga acgatctcta aatgatataa ctgagccaat tcaatgaaat tagcgtatgt
    42361 atatcggtct gttgctattc tatcacctgg agagaaaagt gcagaaagtg tgatagccaa
    42421 tccattttga acaccggaaa caatagatag agattctaag gacggaatga ctccttgagt
    42481 ttttaaccaa tttgctgcag tagtcaattg aaaatttgtg cctttgggat cttggtaatt
    42541 aagcaaacca acaagatttg ggttattact agttgattga ataaacggga caacgaattt
    42601 attacattct tcaaaagaac taaccagacc aaaatcaatg atatgttcgg ttacttcatt
    42661 ggtagagatg gtgatggact caaagacatt gggagaaata aatgtgccac ttccaatatt
    42721 cgtatacagc aaacctttct caattccata tttataagcc ttgccaacgg tagtaaaatt
    42781 taaatctaaa taatcagcta gctctctttg ggagggtaac tgagtgtttt tctgtaattt
    42841 attctttaaa atatcttgtt ctaattgttg aatcaacgat cgataataag gacgcttcaa
    42901 tttttgtttg tctggtcgcc aagttaacgg gtaattgtca taagaattaa taggcatttt
    42961 ctccactcct taaaattgta taccatacaa ttttaccatt gattgtattg attttagaag
    43021 ttaatctttt gtgaggaggg aattgtctat gaaaattatt aattttgagg aagtagtagc
    43081 ttcttttagt tttgaagaag cgattcaagt aatgaaaaaa tgtttttttg attatgaaag
    43141 tggtaaaatc agccaaaatc ctcgattggt ggaaatttta cctgacggaa aaggcaaaaa
    43201 tatgtttgcg atgatgcctg cttatttggg ggagaacaga tattttggca caaaagtcat
    43261 taccgctttt ccggataatc atcagtatca tttaccttct catttaggag agattttctt
    43321 gtttgatgct caaaacggac tacccaaagc attgataaac gcaaatgcag tcacctggat
    43381 tcgaacagct gctgtatctg cgctggcaac agattactta gcaaatccgc atgcagaaac
    43441 acttgcttta attggagctg gtcaacaagc attgtcgcat ttgactgcga tttctaccat
    43501 tcgtcccatc actacagtgt ttgtttacga tattttagaa gaaagacgaa atacttttat
    43561 cgctaaagct aaaaaacagt atcctaaaat aacgtttata aatgcaatat cagtagaaga
    43621 tgcagtacgt ccagcggaaa tcatttgtac gttgacctct agtaaagagg catttcttca
    43681 aaaagagtgg gtaagggaag acgcacatat caatgctgtg ggcacattta ctcctgatac
    43741 aagagagata agtacatcgt tgatggaaac ttctcaaatc tatgtagatg attactcagc
    43801 tgccttaaca gaaagcgggg acctgcttat agccatggca gaaggagatt tagaggaatc
    43861 ttgtattgtt ggtacattag gcgaattagt ttctgagaaa aaaacatttt ataaaggaga
    43921 atcgaggccg acgattttcg acgcagttgg tctagctatt gaagatcttt gttgtgcaga
    43981 atatatttat aacaaattag agaaaggggc tttaaaatga acttagatta ttacgtagtt
    44041 gatgcatttg cagatgaggt gttcaaagga aatccagcag cggtttatgt gctagaagaa
    44101 tggctgccag aaggtacgat gcaaaaaatt gccattgaaa acaatttatc tgaaacagca
    44161 tttacagtga agaaaaacca agaatttgag cttagatggt ttacgccaga tcgagaaatc
    44221 gatctttgtg gtcacgcgac attagcaaca gcatttgttt tatttaacta ttacaaaata
    44281 cctgatgaaa cgattaaatt ttctactcaa agcggtaatc tatttgtgac aagaattaaa
    44341 gattattatt acatggattt tcctagtatt atgccgaaaa aagtgccgat attgtctgaa
    44401 tatgaagaag cgattggggc taagattaaa gaagcctact tagcacgtga tttatttttc
    44461 gtattagaag atgaaaaaac ggtggctaaa ttgcagccag attttacagc tatcaaaaat
    44521 tttgaattag gaataggagt catcgtgaca gcagaaagtg tgcaaaaaga ctttgtttct
    44581 agaaccttct ttccaaaatt aacaatcaat gaagatccag tatgtggatc agcacattct
    44641 aatcttattc cttattgggc agaaagaatg aataaaacaa aattgtcagc ttatcaaatg
    44701 tcatcaaggg gcggggatct agaatgtgaa ttaaaagaag atcgtgtgat aataggagga
    44761 aaagcagttt tgttttctaa aggtacctcg tttatttgat ttctttcaaa tgaattaaaa
    44821 ataaattggt ggagagtggc aaccttatag ctacaatggt tgttaaaaaa agacgcaaac
    44881 tttttcaatt taatgaaaag tttgcgtctc attttaatta ttggtgtttg ttttttattc
    44941 aatcaagagt aaaatgcccc atactaacta tcctcggatg acttcgattt tataaccatc
    45001 agggtcaatg acaaagtagt aagaaggcgc agtgccaggt aatcctttta agtcagtaat
    45061 ctcaagacca gcagctttat gttgctcgtg taatttttct agatcatcag ctgctatagc
    45121 gatatgacca tagccgtctc ctagatcata cgcaccatga tcatagttgt aagtcaactc
    45181 taattcatag tcatccccag gaagtgtcaa ataaacaagt gtaaatttgt tttctggaaa
    45241 atcacggcgg cggctttctt caaaaccaaa tgccttttga taaaattcga ttgatgcttc
    45301 aagatctttc actcgaacac atgtgtgagc cattttcata gattcatctc tccttttcct
    45361 tttactcaat cataacaaaa agaagtaagg aaatagttga tttgtgcttg ttcatgagaa
    45421 atttctcatg taaaatggat agaaaataaa actgttaagg tggaaactat tcatggataa
    45481 accaattttt ggtgaaaaaa agcaatttgc tgattatcaa acccgttatg cagcatatat
    45541 tgtcatagaa agagatcagc agattgcagt aatcgaggct ccaaatggtg ctttttttct
    45601 tcctggcggg gaaattgaag gagaagagac gaaagaagaa gcgattgtcc gtgagctgat
    45661 agaagaaatg ggaattgtgg cagaaatttc ttcttatctg ggagaagctg atgagtattt
    45721 ttactcgaat tatcgtgcaa cttattatta taatccagga tatttctttg ttgctgattc
    45781 ttggaagcgt ataggagaac caactgaaaa gaccaataaa atttggtggg tgagccctca
    45841 agaagcgctt gtgaaattga aacgtggtag ccaccgatgg gcagtcgaga gatggatcga
    45901 aaaaaataaa aactgaaaga aagcgagtag atcagctttc tctcagtttt tttatttatt
    45961 acagtacata ttttttgatt gcttcagcta caccgtgctc gtcgtttgat gaagtgatga
    46021 catttgctgc ttctttgaca agagaaacgg catttcccat tgctactcct agaccagcat
    46081 attcaatcat ggataagtcg ttctcgttat ctccgatagc catgatttca tcttgatcaa
    46141 taccaaggtg ctgtgcgaga ttcgcaactg ccgcaccttt acttgcttct ttatttagta
    46201 cttcgaagta atagggcgca cttttgaccg ttgtgtattt atcacggaaa gtttgcggta
    46261 aacgcgcaat tgctgcatct aaaatttctg gttcgtcgat catcatcatt ttgacgatgt
    46321 tcatgtctgg tgtcatttct tcaggtgttc gatattttag cggcatcttg actaaacttg
    46381 cttcgtggat cgtataagcg ctgatatctc gattaggcgt gtagatcgct ttgtcatcga
    46441 tcgaatggag atgactgccg acacggcgtg ccatcacttc gatctctagg aaatcttcat
    46501 gtgtcagtcc gtgacgggcg atgattttac ctgatttcgt ttgttgtacg agtgccccgt
    46561 tataagtaat aacgtaatca ttatcttgaa aaaggttcaa ctcgtttaac tgttcctgga
    46621 cacctggtaa gggacggcca gtgcataaaa cgatcgaaac accttttgca acagcagcgg
    46681 caatcgcttc ttttacttct tttgttactt ctcttttctc atttaataaa gtaccatcga
    46741 tgtcgatagc gactagtttg atagacataa tttcctccaa tatattttaa tttatttcaa
    46801 tcaatgcgcc attacggata tggctggcaa attcttgata agtttcgtca aataaatcat
    46861 aatgatcacg caaggacgga tcaaccattt cttttggaaa gaaaaatcgc tcatctcctt
    46921 gttcttgtcc cgctaatgca gcaacaagct gactaacctg tgataattct atcaaagttc
    46981 cgtcatttcg caaaatctcg atttgtgtgc gatgtctgcc ttgttctggg cgataaaaat
    47041 cataaggtag atcgtagcta gaattcacag cagtgtaata aacaggatta tatccgacct
    47101 tttctactaa caaagtgagt tcttggacta attttgaatc ccggttgcca gaaaaagtag
    47161 cagatttcag tggtttacga ttcaaaaaac gtttagctaa atcatttaaa ataggatcag
    47221 cagattcaga ccattgagta aagtaagtgc ccaagacccc atcatcaagt ttgaggtatt
    47281 cttctaaagt aaagcttccg tcaagaaatg gcagaagtaa ttgagaatgg agttcaaaac
    47341 tgctggcatc ttcttgatac aactcgtgtg cgcgatgaag cagatgctcc aaaattactt
    47401 ccataccacg ggaaacagga tggaagtaca cttgcacata catttgatat cggctaacga
    47461 tataatcttc cactgcatgc atgccactca tggaaaaagc gatcccgcct tcataaggac
    47521 gaatcacacg taatattcgg gtaagatcaa atgttccata ttctgttcca gtgaaataag
    47581 catcccgaag caaatagtcc attcgatctg catcgatctg actagaaatc atttggacaa
    47641 cttgtgggtt ggggtaagtt ttttggatca cactagctac cttttcagga aaaccttctt
    47701 ctactcggtt aagaatctga tacacttctg tttctggaga agtgatgatc tctacagtga
    47761 tggcttcatg attcgtatgg aagatatgtt caaatgtatg agagtaagga ccatgaccga
    47821 catcatgcaa cagtgccgca cataaagtca ccagccgttc ctgatcatcc cagcctccgt
    47881 tgcctatttt ttcttttgaa aaatttcgag aaaagatatc gcagattcgt cttgaaatct
    47941 cataaacgcc taatgaatga gtaaaacggc tatgttctgc tccgtgaaaa gtgaaagaag
    48001 aagtgcctaa ttgtttaatg cgtcgtagac gttggacttc tttcgaattg atcaaatcta
    48061 agattacttg atgctggaca tggatatagt tatggactgg atcacgaaaa actttttcca
    48121 taggcagcat ttgatattta taaggggttg tcataatgta gctcctttat gttattacgt
    48181 tgttccattc tctggatttg gttgttccat tgctccagct ggatttcttt ttttagccag
    48241 tcggtagaat cctgtaaatc acttgcagaa tacagctttt caaaagcttt tgcaaatgct
    48301 tctttgactt cttttacaaa aaggggttgg tcaagcagtt cttcaagtgt tgccattgta
    48361 gcaggatcca ctgcaggata gccatttgta ccaaagtctt cttttaaagc agattgataa
    48421 aatcgcttca tgacttgccc gcgtttttcc tgattaccgt tgacacttaa gtacatcata
    48481 acagaaatcc catttttgat ccgacgctga gcgataccgg caaatttttt gccatggatg
    48541 cttaaatcat aagttccagg acaataagaa tgggtgattt cgaatgcttg tatcggtgcc
    48601 tttggaaaag cgtatttagt caataggagc atttgctcgt aagcgtcatc tatggttatt
    48661 ttttttgtgt cactttgggg gaaaatcaaa gaaatattca aaattccttc atctgatacg
    48721 atccctaatc cacctgaatt tctgatcact ggagcgtaac ctgcatcttt cagtgtttgg
    48781 atcccgtcac ttagaaaagg agttcgaaca tccttcatac ctaagatgac tgtgcagtca
    48841 tattgccaga aatgtaaaaa gatttgctgg tgttctttag aatattccgt taatatatct
    48901 gttaatgcaa aaggggaaaa gtcgtttttt tgataaatgt gctgatctag tcgaatcgca
    48961 gggttcattc aaccggctcc tttgtataaa ttcatatttt ctacaatatt atactctaaa
    49021 atcaaagagt tgttttggaa aaaaggtttt ctgtaaaaat ggacaagttg gttgacaaaa
    49081 caaaagaaac taggaacaat gtagctatga gaagtaaagg agaatgaata atggaattat
    49141 cacaaggaac accgatttca atcaaattgc gtacaaaagt aaaacagcaa ggggaagtgc
    49201 aagattttta ttttgatttg aaagggcaaa tggtgacaat tggcgatacg ctgtacatac
    49261 gttataaaga gattcaggag gagacgggcg atgagattcc tgtaacgatc aaattagttc
    49321 cagatggtca tgtacagctg atccgtgcag gagaaatgcg gatgcgtttg aaatttggct
    49381 ataaagaacg gttagaaaca tcctatcgaa caccatacgg tatgatccag attgctactt
    49441 ttacgaaaga actgcatgtt agtttgaaag accgtcccac agcagggaag gttcgaatcg
    49501 attatgatct gttcatggga ccggaaaaaa tcggcgaata ttatttgacc ttggatttta
    49561 cagcgtaaat ataaaagaaa agtttgattt tttgtgtctg attttgtatg ataaggagta
    49621 gactgtgaaa ggacgtgtcc tgattggaaa ttagtgtatt tgaaggtgca aacaaaagcg
    49681 aattatcaat gatcgaagta gcacacgcga tcttagaaca acgtggcgat gtcatggatt
    49741 tttctgattt agctaaccag atccaaaact atcttgggaa atcagacagt gaaattcgtg
    49801 attcactcgc acaattttat actgacttga atattgacgg cagctttatc tcattagggg
    49861 ataatcgttg gggcttgcgt tcatggtatg ctatcgattc gatcgatgaa gaagtaaacc
    49921 atggaatgga cgaagaggat gaagatactc cacgtcgccg taaacgcaag aaagtcaacg
    49981 cctttatcaa tgatgatgaa gacgcgatcg attacaatga cgatgaccca gaagatacag
    50041 atctgacaga agaagatgac gatgatctgt ttgatgacga tgatgatgaa gatgaagaaa
    50101 tcgctgctta taattctgac ttgcaagaaa tcggagcaga tgacccgaca gatgatgaag
    50161 aagacttgcc aggaaatatc gaagaagatt taagtatcat agacgaagac gatgatgatg
    50221 aagattatga agaggaagaa ttttctgact ctgaaaaaga ataaacatta ttttcttacg
    50281 agaggttgtg acagagacga tcagcctatc agaataagga ggtgtgacac gatttttgtc
    50341 acaccttctt ttttgtatat aaaaatccca agtaaataca taaaaaataa aaaaattgaa
    50401 acttttagcg caccttgtac gtcatattaa gtgaggcaga aaggagtgga gaatgatttt
    50461 tactggatat aagaaaaaac ggcagatcga aaaataccgt cacctgctga atggactcat
    50521 cgaaactgat tatcaaaaaa tgttccgtat cacgatgaat tacgtacatg ataaagaaga
    50581 ggccttagat gtgatgcaag atagttttca taaagccctg aactattttg aaaaagaaaa
    50641 agagatcgag cattttagtg catggtttta tcggatattg atccgcacgg cattagatag
    50701 ttggcgcaga caaaaaagga cgcctgtgga cttatttgaa attcaagata tcccccaaca
    50761 gttaccttta gaaacttccg ttgcagagct ccatatgatt ttagataaaa tagacagtcc
    50821 ggaaaaagag attctgatcc tctacttttt tgaaggattt cgtttgaaag aaattgcgac
    50881 tatcttggat atgaatgaaa acacagttaa aacgaaaatg taccgctcat tgaatgcttt
    50941 acgtcaaatc ctagaatgaa ggagagaaga gtgccatgta ttcccaaaaa gaaaatttaa
    51001 aaaaactaaa gaaaacttat aaagaacaag caattcccaa agggcttaaa gaggagatcc
    51061 gccagcgttt tattatcgaa gagcaatcat ttataaaagc aaagcggaga aagagacgtc
    51121 tccaagggtt cggagtatct ttggctatcg taatgattac aacaagtagc cttcttttta
    51181 atagtcaagt tcgaagcttt gcagaagatt tacccatctt aggatcagtc attgaattga
    51241 tcttaggcga acgctttact gatcgatctg aaaaaatcga tattcaggta ccgaagatca
    51301 atacacaaaa tgagaaagaa aataaaacaa ttcatggatt aaatcaaaaa tactttcgcg
    51361 aaggacaagc agattttgaa aaagctgaaa aagaatatgg aaattttgaa acggatcatt
    51421 accaagtttt gggagattat cagaaaatcg tagacgataa ccggtttctc gtgattgaaa
    51481 ggcagatcac ccaaacagca gcagatagcc atgttgaaaa aagatacgac acaatcgaca
    51541 agaaaaacag tgtccagctc tcacttccac ttttattcaa agatgacacc tatctatctg
    51601 ttttgacaaa agaagtcaaa cggcagatgg ccgaacaagt caaggaagat ccatctaagt
    51661 actattggac tgagcaagat attcaagaag ggacgataga aaaaccaaca cttgttacgc
    51721 ctacacgaag tttttatttg aacaaagagc atcaattagt tttgactttt tctcaatacg
    51781 aaattgctcc tggttatatg ggtacaccag aatttgtcat tcctaagtcc gtgacaaaaa
    51841 cgattttggc atcggaagat tatttggatc attagacgag aagtagttgc gactagcagt
    51901 ttcaattttc aagtaagtac aagtaaataa taagaagaga aaaagagaaa gaagagatat
    51961 agtgaaaaga aattatttag ttatcagtat tattgcttta tccgtgcttt tgtttttcga
    52021 aattacttcg gtggcctcct tgatcaccga agtaaaagga caaacacact cttcggagca
    52081 ttcgtcacaa tctttcaaac aatcagaaca atcaaccatt aaaagccaat caactgaaac
    52141 agctaacgtc aaagaagcca ttcaagaatc agcggaaaag gtacaaagtc agtcatcaca
    52201 atcaacacaa gacagtacaa aaacgagccg agatccggct gtcaaaagcg tcgcaatcag
    52261 ctttgatgat ggaccaggag cgaccacaac accgcagctt ctgcgaatct taaaagaaaa
    52321 aaacgtgcat gccacttttt tcgtcttagg agaaaatacg gcgcagcatc ctgaaatcgt
    52381 gaagcagaca gctgaagcag ggcacgagat tggcaatcac acatacgatc atcagaatct
    52441 ggccactctt tctgcccagt cgatgacgga ggaagtgacg aaagcagaca ctgagatcaa
    52501 aaaagtcact ggcaaaaccc ccacttttgt tcgtccgccc tatggttctg tcacgaatgt
    52561 aggagcaacg atcatccagc gaccgatcat cgaatggtct gttgattcag aagattggaa
    52621 gacaagaaat cctgatttga ttttgcagaa gatccaagca acagtatacg atggggcaat
    52681 tattttattc catgatatct atcctgaaac gattcgtgcc gttcctcaag tgatcgatta
    52741 tctgaaagag caagggtatc gcatcacgac agttggggat ttattagggc atccaacggc
    52801 tgtcgagaac tattatggca gaaacgatca tcggccagtt cagtaagtga gacaagtatc
    52861 tttaataaat aacacatttt aataagtagt tgaacacata actaccttac ttgcaaaggc
    52921 ttaacaatat ctatacaggt acaacaaaaa actgtccacc aattttcttt ggcggacagt
    52981 tttcacttaa aaataaagaa gcaactattc gtaaattatg ctaaaatagc agtagaacgc
    53041 gtcctgaggg aatcgaaccc ccgtctcaag aaccggaatc ttacgtgata tccactacac
    53101 taaggacgca agcactggga taattgtaac taaacagata aaaaattaca aggggattgg
    53161 acaaaaaaat gaaatttgag caaaattttt cacaaaaaca gcagcagaca cagaaactag
    53221 ccatgacgca acagttgcaa cagtccatcc aagttttaca atataacagt gaggagctgt
    53281 tggcattcgt tgagaatcaa gcaatggaaa atccattggt ggaagttgtt gagccggaat
    53341 ggcagccaga ttacataaaa gcttcttcat cttcttatga aggagaagag acaaattacc
    53401 taaatcagat tcctgataca aaagggtctt tatttgattc attgatcgaa caagtccatt
    53461 tgaattaccg agatactttt ttgaggaaaa tcgttcttta tcttgtagaa tacatcgatt
    53521 tgaacggatt tttgacgatt agtttagaag aagccggaaa agagattgga gctacgccta
    53581 tccaaatgct cgatgcgttg actctgattc agcaattaga accagctgga gtaggtgcac
    53641 gtagtttgca agaatgtctc atgcttcaaa cagaacgaga tgattatgcg ccggaattag
    53701 cttatatcgt gttggaagaa tgttttgagg aactggtgga gcgaaaatgg aaagaaatcg
    53761 cacaacgttt ttctgttgat ctacatgctg ttcagcagat attcgactat ttacaaacgt
    53821 tgagtccaag ccctggccgg attttcgacc gtagcagcga attgtacatt attcctgatg
    53881 tccgggtatt agtggacgac gataaaaatg tacaagttat ctcaaaccga aaaaatcagc
    53941 caaatatacg ctttcaagag agttacttca aacaaatgtc acaacaagca gataaagaaa
    54001 ctgaaaatta tttaaaagaa cggaaacagg aattcgaatg gttgaagaaa acgatcctac
    54061 aacgtgggga tacaattttg cgggttgctc aagtcattgt ttcccggcaa aaagctttct
    54121 ttatcgacaa ggaacgtcca atcaagcctc ttacgttaaa ggaagttgca actgagatag
    54181 atgtgcatga atccacggtc agtcgtgcag tcaacgggaa atatttggaa acagacttcg
    54241 gtgtatttga attaaaaaaa tttttcacta cacgaattcc tacgaatagt acagaacaga
    54301 cagaagacct ttcagcagat acagcgaaga aaaagctgca ggaattagtc gatcaagaag
    54361 acaaaaacaa gccgttgtct gaccagaaat tggttgaatt gctgaaaaaa gatgagatag
    54421 cgatctcaag acgaacagta gcaaaatatc gtgatttatt aggaatcccg agttcatcaa
    54481 aaagaaaacg ttatgataac taatcagtca aaagactaga aaaagtattt cactttttct
    54541 agtcttttta gttgaaaaac gagagcaaaa ctgttagact tacagtcgtg aggttgagat
    54601 ttccctttat tgatgtgaaa ttcgaatagt taatttcttt ttttatcgta tatgggtcgt
    54661 tttaagtcta cattggacgt aaagtgtcca actaaggaga tcgctatgct ggatgaaata
    54721 aaaatgattg aatctgttgc accagatatt atcgaagtgt tgcaagaacg ctataaaatt
    54781 ttacgaaata tctattggat gcagccgatt ggacgtcgaa gtttatcgga aagtatgggg
    54841 atcacagaac gagtattgcg aacagaaaca gatcttttga aaaatctgaa tttgatcgac
    54901 acctcaaaaa gcggtatgac gctgacaact aagggcgaag aagtttatca aagccttgaa
    54961 aacttcatgg atcagctttt aggtacgcat caaaccgaac aacagttggc agaatatttt
    55021 ggtaaccaac gctgtatcgt tgtttcagga aacagcgaag agcagaccaa agtggctgat
    55081 gcattcggcg aagcgctgag cgaagcccta gaccgactac ttccagaagg cgagaatatc
    55141 atcgctgtga tgggaggaac tactatggct gtggtagccg aacaattgtc taatctggaa
    55201 aataagaaac ggcataacct gtttgtccct gcaagaggcg ggattggtga agcgataact
    55261 gtacaggcaa attctgtcag tgcaagaatg gctgctaaag caaacggtaa ccaccgtgca
    55321 ctttatgttc cggaacaatt aagtctggca acttacaatt ctttactcaa tgagccatct
    55381 atccaagaag tcttaaactt gattagtgaa gcgaattgtg ttattcatag tattgggcgt
    55441 gcattacaca tggcagcacg tcgtaagatg actgaaaaag aattagtcat gctgaaacaa
    55501 gcaaatgctg ttgcggaatc ttttggctac tttttcaatg aaaaaggtga agtcgtttat
    55561 aaggtcccta gaatcggcat agaattgcaa gatttggaaa aagtcccgat catcatggca
    55621 atcgcgggcg gaaaatcaaa agctaaagca attcgagctt atatgaaaaa tgcaccaaaa
    55681 caaacgtggc tcatcactga tgaagctgct gcaaatgaga ttttaaaagg ggtaaccctt
    55741 taaaataaat atttttttga ttttcataag gaggaaatct taaatgacag ttaaagtagg
    55801 tattaatggt tttggacgta ttggacgtct agcattccgt cgtatccaag atgtagatgg
    55861 aatcgaagta gtagcaatca acgacttgac agatgctaaa atgttggcac acttgttaaa
    55921 atacgacaca actcaaggac gtttcaacgg aacagttgaa gttcatgaag gttcattcaa
    55981 cgtaaacgga aaagaagtta aagtattagc taaccgcaac ccagaagaat taccatgggg
    56041 cgaactaggc gtagatatcg ttctagaatg tactggtttc ttcacttcta aatcagcagc
    56101 tgaaaaacat ttaacagctg gtgctaaacg cgttgttatc tctgctcctg gcggaaacga
    56161 tgttccaaca atcgtttata acacaaacca cgaaacatta actggtaaag aaacagttat
    56221 ctcaggtgct tcatgtacta ctaactgttt agctcctatg gctaaaacat tgaacgacaa
    56281 atttggtgtt gttgaaggat taatgacaac tatccacgct tacacaggtg accaaatgac
    56341 tctagacgga cctcatccta aaggtgactt ccgccgtgca cgcgctgctg ctgcaaacat
    56401 cgttcctaac tcaacaggtg ctgctaaagc tatcggttta gtaattcctg aattgaacgg
    56461 taaattagac ggagctgctc aacgtgttcc tgtaccaaca ggttcattaa cagaattagt
    56521 aacagttctt gaaaaagaag taactgttga cgaaatcaat gcagcaatga aagaagcttc
    56581 aaacgaatct tacggataca acacagacga aatcgtttct tcagatatcg ttggtatgac
    56641 ttacggttca ttatttgatg ctacacaaac taaagtaatg acagttggcg acaaacaatt
    56701 agttaaaact gttgcttggt acgacaacga aatgtcatac actgcacaat tagtacgtac
    56761 tttagaatac ttcgctaact tataagatag acaaacgtac aagtgtaaat tatagacatg
    56821 tacatttaaa agcggggaag caatcgcgct tcttccgctt tttttgataa taagtttatt
    56881 caggaggaaa taaaatggct aagaaaacag tgaaagatat cgatttaaaa gacaaaaaag
    56941 ttcttgtccg tgttgacttc aacgttcctt tgaaagacgg cgtgatcact gacgacactc
    57001 gtatcaaagc agcattgcca acaatcaact acgttctaga acaaggcgga aaagcaatcc
    57061 ttttctctca ccttggacgt gtaaaaacag aagaagataa agaaggaaaa tctttagctc
    57121 cagttgcaaa acgtctaggc gaattattag gtaaagaagt aacattcgta cctgaaactc
    57181 gcggagaaca attagaagaa gcaatccgca acatgaatga cggcgacgtt gtcgtattcg
    57241 aaaatacacg atttgaagat attgacggta aaaaagaaag caaaaatgat acagaactag
    57301 gtaaatactg ggcttcatta ggcgatgtat ttgttaacga tgctttcggt acagctcacc
    57361 gtgcacatgc ttctaacgta ggtatcgctt caactggtat cccaacagtt gctggattct
    57421 tgatggaaaa agaaatcaag ttcatcggtg aagcagtaga agaaccaaaa cgaccaatga
    57481 ttgcaatcct tggtggcgca aaagtttctg ataaaatcgg cgtaatcgaa aacttgattc
    57541 ctaaagcaga taaaatcttg atcggtggcg gaatgactta cacattctac gaagcaaaag
    57601 gaatcaagat cggtaactct ctagtagaag ctgataaagt ggaactagca aaagaattaa
    57661 tcgaaaaagc aggcgacaaa cttgtcttgc caatcgacaa tgtctgtgca ccagaatttt
    57721 caaatgatgt tgaaacacaa gtaatcgaag gagacattcc tgatggtttg atggctttag
    57781 acatcggccc agcatcagta aaattatttg ctgatacatt acaaggtgca aaaacagttg
    57841 tttggaacgg acctatgggt gtatttgaaa tgagtaactt tgctaaaggt acaatcggtg
    57901 tttgtgaagc aatcgctaac ttagaaggcg caacaacaat catcggtggc ggagactcag
    57961 ccgcagcagc agaacaatta ggatttgctg acaaattcac acacatctca acaggtggcg
    58021 gcgcaagctt ggaattgctt gaaggtaaag aattaccagg actagcagca atcaacgata
    58081 aataaacgac caagtttgct caattctgac gagtaatcga acaaaaggtg aagggagttt
    58141 tcatgactcc ctagccattt ttcaataaat taaggagtgt gttcctcaat gcgtaaacct
    58201 attatcgcag gtaactggaa aatgaacaaa actgcatcag aagcaaaaga atttgctgaa
    58261 gcagtaaaaa acaaaatccc ttcaaatgac aaagttgatt cagtcatcgg atctcctgca
    58321 ttattcttac aagaattaat gacatcagct gaaggtacag aactaaaaat ctcagcacaa
    58381 aactgctact gggaaaactc aggtgcgttc actggtgaaa cttcaccagc agctcttgct
    58441 gatctaggtg ttcattatgt gatcatcgga cattcagaac gtcgtgaata tttccatgaa
    58501 acagacgaag acatcaataa aaaagcgaaa gctatctttg caaatggtat gacaccaatc
    58561 ctatgctgtg gcgaatcttt agaaacctat gaagcaggca aaactgctga atggatcgaa
    58621 ggacaaatta cagctggttt agctgatctt tcagctgaac aggtgtcaaa catggttatt
    58681 gcttatgaac caatctgggc aatcggtact ggtaaatcag ctgacgcaca aatcgctgac
    58741 gaaatttgtg gagttgtacg tcaaacagtt gaaaaacttt atggaaaaga agtatcagaa
    58801 gcagttcgta tccaatacgg cggttctgta aaaccagaaa atattgctga atacatggca
    58861 aaagaaaatg ttgacggtgc tttagtcggt ggcgcaagct tgcaagcaga ttcattcttg
    58921 tcattgttag acgctgtaaa ataattgttg aaaatttgcg aaaaatgcaa gaaatgtttg
    58981 cactaatgag caaaattaac taaaatcgta tatgagggaa atcccttagg aaaaaacaaa
    59041 ctcaaaggag agacaaaaca tgtcaattat tactgatgtt tacgctcgcg agatcttaga
    59101 ctcacgtggt aacccaacaa tcgaagtaga agtatacaca gaaagcggag cttttggccg
    59161 cggaatggtt ccttcaggtg cttcaactgg tgaatacgaa gcagttgaat tacgtgacgg
    59221 agacaaagct cgttatggcg gtaaaggtgt aactaaagct gtcgacaacg taaacaacat
    59281 cattgctgaa gcaatcattg gctacgatgt tcgtgaccaa atggctatcg acaaagctat
    59341 gatcgcttta gacggaactc ctaacaaagg taaattaggt gcgaacgcta ttttaggtgt
    59401 ttctatcgct gttgcacgtg cagctgctga ctacctagaa gtacctttat accactacct
    59461 aggcggattc aacacaaaag tattgccaac accaatgatg aacatcatca acggcggatc
    59521 acatgctgat aactcaatcg acttccaaga attcatgatc atgcctgttg gcgctccaac
    59581 attcaaagaa gctctacgta tgggtgctga agtattccac gcattagctt caatcttgaa
    59641 agctcgcgga ttagcaactt ctgttggtga cgaaggtgga tttgctccaa accttggttc
    59701 aaacgaagaa ggttttgaag taatcatcga agcaatcgaa aaagctggct atgtacctgg
    59761 taaagacgtt gttcttgcta tggatgctgc ttcttcagaa ttctacgaca aagaaaaagg
    59821 tgtttacgta ctagctgatt caggcgaagg cgaaaaaaca actgacgaaa tgatcaaatt
    59881 ctacgaagaa ttagtttcta aatatccaat catctcaatc gaagacggat tagacgaaaa
    59941 cgactgggac ggattcaaga aattaactga cgtattaggc gacaaagttc aattagttgg
    60001 tgacgacttg ttcgtaacaa acactcaaaa attatctgaa ggtatcgaaa aaggaattgc
    60061 taactcaatc cttatcaaag tgaaccaaat cggtacatta acagaaactt tcgaagctat
    60121 cgaaatggct aaagaagctg gctacacagc agttgtatct caccgttctg gtgaaacaga
    60181 agattcaaca atctctgata tcgctgttgc aacaaacgct ggccaaatca aaactggttc
    60241 tctatcacgt actgaccgta ttgctaaata caaccaatta ctacgtatcg aagaccaact
    60301 tggtgaagtt gcagaataca aaggtttgaa atctttctac aacttaaaaa acaaataatt
    60361 cttttctaat gaagatacat gatcgactat tgaaagatag tcgagtatga tcacttagtt
    60421 aagtaatcga actctctact tgctgaaata tcagcaggta gagagttttt ttgcaactag
    60481 cttctgtata tgatgtttac aaagaatggt acaagaaaag atcatccttg aaaaaggaaa
    60541 gctaacaata actagcatca tataagagct tttaaggata gaacagtaga ataggaatct
    60601 atgagcaagt cctctcgtat aaataaaata ggagggaagt agcagcatat ttttcataaa
    60661 gtggctctct ttcttcattt ttactttggt tgctcctatt tgaaaattcg agcacactca
    60721 aatacaataa aaagaaatgg caagggagag gattagatga aaaaagaaga aaaaatcgcg
    60781 attttacaag agatcatccg aattaaatca gtgaatggaa acgaaggtga agtagcagcc
    60841 tatttgaata agcttttggc aaagcatgac ataacaggag agattgtttc ttacagagat
    60901 ggtagagata atttgattgc tcgttaccaa aagggccaat caggaaaagt gttaggccta
    60961 tctgggcata tggatgtcgt ggcggctggt gatgaatcgt cttggaccta tgcacccttt
    61021 gcagcagaaa tccatgggaa ccgtttgtac ggacgtggtg ctacagatat gaagagtggc
    61081 ttggcagcaa tggtgattgc catgatcgaa ctgaaagagt caggaaaacc atttaacgga
    61141 acagtcaaat tattagccac tgtcggagaa gaagtgggtg aactaggtgg ggaacagctc
    61201 acgaaagcag gctatgtaga tgacttagat gccttgatca tcggagagcc aaccaattac
    61261 agtttgatgt atacgcacat gggatcaatc aactatacag tcacctcgca cggaaaagaa
    61321 gcgcatagct ctatgccaga ccaaggttat aatgcaatca atcacctaaa tgaattcatt
    61381 acgaaagcaa atgctgaaat gaatcacctc gctgaaacaa tcgagaatcc tgtcctagga
    61441 aaaacaatcc ataatgttac attgatcagt ggcgggaatc aagtcaacag catcccaagc
    61501 catgcgcagc tccaagggaa cattcgatcg attccagaat acccaaatga taaaatcatt
    61561 gcattgctgc aatcaatcgt caatgaattg aatcaagaga cagactatca tttggaattg
    61621 atgatcgatt acaacaaaat acctgtcaaa gctgatccag attctccttt gattcattgc
    61681 attcagcaac aattcagcca gccattacct ttagttggag cggcagcaac aacggatgca
    61741 gccgaattta cgaaagctaa ccattccttc gactttgtcg tctttgggcc tggtgtcgtt
    61801 actttgcctc atcaagtaga tgagtatgtt gaaatcgata attatttgga tatgatcgaa
    61861 aaatatcaag gaattatttt atcctactta gcgtaagatt tttttaataa atgaaaaaac
    61921 agagccagat tagcatta
//
LOCUS       DADGHT010000004        54422 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.004, whole genome shotgun sequence.
ACCESSION   DADGHT010000004 DADGHT010000000
VERSION     DADGHT010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54422
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.004"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(58..390)
                     /locus_tag="JX887_000198"
     CDS             complement(58..390)
                     /locus_tag="JX887_000198"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256217.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(404..634)
                     /locus_tag="JX887_000199"
     CDS             complement(404..634)
                     /locus_tag="JX887_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256218.1"
                     /translation="MCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQKGYPYGPTN
                     LKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(856..1398)
                     /locus_tag="JX887_000200"
     CDS             complement(856..1398)
                     /locus_tag="JX887_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256219.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(1419..2510)
                     /locus_tag="JX887_000201"
     CDS             complement(1419..2510)
                     /locus_tag="JX887_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAX1256220.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(2518..4728)
                     /locus_tag="JX887_000202"
     CDS             complement(2518..4728)
                     /locus_tag="JX887_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256221.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(4744..7272)
                     /locus_tag="JX887_000203"
     CDS             complement(4744..7272)
                     /locus_tag="JX887_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAX1256222.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(7324..7734)
                     /locus_tag="JX887_000204"
     CDS             complement(7324..7734)
                     /locus_tag="JX887_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256223.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(7747..7965)
                     /locus_tag="JX887_000205"
     CDS             complement(7747..7965)
                     /locus_tag="JX887_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256224.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(7962..8954)
                     /locus_tag="JX887_000206"
     CDS             complement(7962..8954)
                     /locus_tag="JX887_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1256225.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(9033..9944)
                     /locus_tag="JX887_000207"
     CDS             complement(9033..9944)
                     /locus_tag="JX887_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAX1256226.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(9963..10307)
                     /locus_tag="JX887_000208"
     CDS             complement(9963..10307)
                     /locus_tag="JX887_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256227.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(10327..10883)
                     /locus_tag="JX887_000209"
                     /pseudo
     CDS             complement(10327..10883)
                     /locus_tag="JX887_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10964..11464)
                     /locus_tag="JX887_000210"
     CDS             complement(10964..11464)
                     /locus_tag="JX887_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256228.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(11465..12010)
                     /locus_tag="JX887_000211"
     CDS             complement(11465..12010)
                     /locus_tag="JX887_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256229.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(12007..13263)
                     /locus_tag="JX887_000212"
     CDS             complement(12007..13263)
                     /locus_tag="JX887_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAX1256230.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(13624..13935)
                     /locus_tag="JX887_000213"
     CDS             complement(13624..13935)
                     /locus_tag="JX887_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256231.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(13958..15268)
                     /locus_tag="JX887_000214"
     CDS             complement(13958..15268)
                     /locus_tag="JX887_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAX1256232.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(15882..16334)
                     /locus_tag="JX887_000215"
     CDS             complement(15882..16334)
                     /locus_tag="JX887_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256233.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(16336..16701)
                     /locus_tag="JX887_000216"
     CDS             complement(16336..16701)
                     /locus_tag="JX887_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256234.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(16800..21083)
                     /locus_tag="JX887_000217"
     CDS             complement(16800..21083)
                     /locus_tag="JX887_000217"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HAX1256235.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(21230..21469)
                     /locus_tag="JX887_000218"
     CDS             complement(21230..21469)
                     /locus_tag="JX887_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256236.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(21559..21831)
                     /locus_tag="JX887_000219"
     CDS             complement(21559..21831)
                     /locus_tag="JX887_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256237.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(21914..22165)
                     /locus_tag="JX887_000220"
     CDS             complement(21914..22165)
                     /locus_tag="JX887_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256238.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(23161..24071)
                     /locus_tag="JX887_000221"
                     /pseudo
     CDS             complement(23161..24071)
                     /locus_tag="JX887_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(24267..26102)
                     /gene="lepA"
                     /locus_tag="JX887_000222"
     CDS             complement(24267..26102)
                     /gene="lepA"
                     /locus_tag="JX887_000222"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAX1256239.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            26249..27469
                     /locus_tag="JX887_000223"
     CDS             26249..27469
                     /locus_tag="JX887_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1256240.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            27489..27983
                     /locus_tag="JX887_000224"
     CDS             27489..27983
                     /locus_tag="JX887_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAX1256241.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            27976..28647
                     /locus_tag="JX887_000225"
     CDS             27976..28647
                     /locus_tag="JX887_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256242.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(28798..31407)
                     /gene="clpB"
                     /locus_tag="JX887_000226"
     CDS             complement(28798..31407)
                     /gene="clpB"
                     /locus_tag="JX887_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAX1256243.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(31658..32704)
                     /locus_tag="JX887_000227"
     CDS             complement(31658..32704)
                     /locus_tag="JX887_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAX1256244.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(32715..32987)
                     /locus_tag="JX887_000228"
     CDS             complement(32715..32987)
                     /locus_tag="JX887_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAX1256245.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(33022..33930)
                     /locus_tag="JX887_000229"
     CDS             complement(33022..33930)
                     /locus_tag="JX887_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAX1256246.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(34062..35294)
                     /gene="pepT"
                     /locus_tag="JX887_000230"
     CDS             complement(34062..35294)
                     /gene="pepT"
                     /locus_tag="JX887_000230"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAX1256247.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(35309..36430)
                     /locus_tag="JX887_000231"
     CDS             complement(35309..36430)
                     /locus_tag="JX887_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAX1256248.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(36427..37128)
                     /locus_tag="JX887_000232"
     CDS             complement(36427..37128)
                     /locus_tag="JX887_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAX1256249.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            complement(37272..37712)
                     /locus_tag="JX887_000233"
     CDS             complement(37272..37712)
                     /locus_tag="JX887_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAX1256250.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(37841..38767)
                     /gene="dnaI"
                     /locus_tag="JX887_000234"
     CDS             complement(37841..38767)
                     /gene="dnaI"
                     /locus_tag="JX887_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAX1256251.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            complement(38767..40140)
                     /locus_tag="JX887_000235"
     CDS             complement(38767..40140)
                     /locus_tag="JX887_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAX1256252.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            complement(40163..40654)
                     /gene="nrdR"
                     /locus_tag="JX887_000236"
     CDS             complement(40163..40654)
                     /gene="nrdR"
                     /locus_tag="JX887_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAX1256253.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            complement(40966..41298)
                     /locus_tag="JX887_000237"
     CDS             complement(40966..41298)
                     /locus_tag="JX887_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAX1256254.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            complement(41350..41979)
                     /locus_tag="JX887_000238"
     CDS             complement(41350..41979)
                     /locus_tag="JX887_000238"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAX1256255.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEILVGQIENWLFANRFL"
     gene            complement(41943..42779)
                     /gene="mutM"
                     /locus_tag="JX887_000239"
     CDS             complement(41943..42779)
                     /gene="mutM"
                     /locus_tag="JX887_000239"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAX1256256.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            complement(42824..45469)
                     /gene="polA"
                     /locus_tag="JX887_000240"
     CDS             complement(42824..45469)
                     /gene="polA"
                     /locus_tag="JX887_000240"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAX1256257.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            complement(45595..46278)
                     /locus_tag="JX887_000241"
     CDS             complement(45595..46278)
                     /locus_tag="JX887_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAX1256258.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGIILAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            complement(46271..46756)
                     /locus_tag="JX887_000242"
     CDS             complement(46271..46756)
                     /locus_tag="JX887_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAX1256259.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            complement(47063..48397)
                     /locus_tag="JX887_000243"
     CDS             complement(47063..48397)
                     /locus_tag="JX887_000243"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAX1256260.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            complement(48528..49289)
                     /locus_tag="JX887_000244"
     CDS             complement(48528..49289)
                     /locus_tag="JX887_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAX1256261.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            complement(49305..49787)
                     /locus_tag="JX887_000245"
     CDS             complement(49305..49787)
                     /locus_tag="JX887_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAX1256262.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            complement(49807..51987)
                     /locus_tag="JX887_000246"
     CDS             complement(49807..51987)
                     /locus_tag="JX887_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAX1256263.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            complement(52131..52862)
                     /locus_tag="JX887_000247"
     CDS             complement(52131..52862)
                     /locus_tag="JX887_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAX1256264.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            complement(52931..53872)
                     /locus_tag="JX887_000248"
     CDS             complement(52931..53872)
                     /locus_tag="JX887_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAX1256265.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            complement(54052..54420)
                     /locus_tag="JX887_000249"
     CDS             complement(54052..54420)
                     /locus_tag="JX887_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAX1256266.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
BASE COUNT        15305 a        11718 c         8905 g        18494 t
ORIGIN      
        1 ttattctttt cataatttct cctccataaa aaataagtta ctttttaaat atcttgttta
       61 tgaattcatt ccccaaaggc cttttaagat tgatacagca gtccgttcac ttcttttaga
      121 cttgtcatac aagtctttta aatgatccca tatcagacta gtttgtctat ctagcttcaa
      181 tccattaaac gctaatgaac ggttcatttt ttctattact ttagataaag ctacagaaat
      241 ttttatacct tcacaacgcg catcttggat ttcaataata gtatcatcaa ttagtttttg
      301 aatttcttgc ctatcaacat attcaatctt agaaagagaa tcttttaaag ctactaatga
      361 ttcaacgatt tcttttttct cttcagacat tttcttcctc cttctagtga cccgtaaagc
      421 catgtagagc agagtccatt gaaccagtaa ttacactatc tacaacgcca ttccaattta
      481 ctctacattt tccatttttc agatttgtcg gtccatacgg atagcctttt tgacattcaa
      541 tgttcggatt ataccagata ggattatacc attcagccgc agaagcagat tcagtcgata
      601 caaacaatcc cacaccaaca aatccaatac acatcacact atagccaatt agttttttca
      661 tctcgtatcc atctcctaaa aaatagaata gttcttatag ttattcataa gacatatttt
      721 ttccgttttt gttttatcct ttctgtccta taacaacttt tttcaagtaa agaatgacat
      781 agtttttctt aaaaaaacag tctgtttttt tctatttctt cggtgtataa taaatatgag
      841 tgttcatttt ttattttaat acgcactccg tacataataa atcttgatcg catcaatctt
      901 ttgagcttct tgatctactt tcaattgaag taatacaaat tgagtaacct tattcattgt
      961 ttcttctcca aataacaaat attgatccgg attctctata tcttgtgtca cctggtaaag
     1021 tttcccagtt gttttcattt gtacatgcgg gtctacatca atactattgt ctttaataca
     1081 acgatctgtc atatagtccc tcacagcttg attgcgttta taaacatctg tgaaattact
     1141 ccattttcta gcaaaatctt ttaagaaatt ttttgtcatt tcatctattt gcatttgttg
     1201 cgctgtctcg tcttctaatg aaccaatttg actgttactt tcagtacttt gaagagttcc
     1261 acttgtttct tttactgctt cgattgtttc ttctgtcgtt ctcaattgtg ttttttgttt
     1321 ttcagaagaa aaccaatgac aaccagtaag acctatcaaa cataaccaac taaatactaa
     1381 aattatccct tttttcacgt ttctagtcac tgcctttctt atttcacctt acgaaccaga
     1441 ctacgaattt ttgtttgatt gtacgtgcgt tgataccgag ccataatccg tccttgctcg
     1501 gcattctgtt ccacactaga gaaatgttgt ccgccatatg aaacatctgt tataattccg
     1561 gtgtgaccat agattccagg agacaatgca ccacctgctt gccaattcac cacatctcct
     1621 gcttgtaaat cacttggttt tgggttcatg attacttgcc aaccataggt tgtccagtta
     1681 taatcttccc ctattaacat cgcaaacatg tgtccagaac ccattaactg tgggccacct
     1741 aattgagata cataccatgc cgtaccacca taacattccc cattatttac ggatcgtcca
     1801 atgatccgat ccaaaacctt cgcattgcct ttactttttc ctgcaataag cgaagttttt
     1861 tttgttggta ggctattcca atgcttgatc gcaaaagtat catattccgt taagttatag
     1921 gacgttatga tactcattgc tcctcgataa tacggactcc cttcggtaat acctgctgcc
     1981 gcatagcctc cacgacctag aatcaataaa caacttccag gatctttatt gcccacacat
     2041 tgattaaagt tgctttggct cgccaccata aagccataat agtcataaca agcttttaag
     2101 ttcggaaact tcatatagaa accaccttca gaaccaccaa ttccacgtgc agaaccttgt
     2161 gggtagggac aaccaggaaa ccaggtaatc ccaaaaaagt tcgtatcgtt tcttccagat
     2221 tgtgactgtc cataagctga ttcatagcct aattgagaaa gaatcacact cggtaataac
     2281 tgatacttta cagctgcacc aactgctgct tgcgcatgtt catctgtgat tggaccacgt
     2341 cctttaatct ctgaaaaaat cggtaatcct tcggtatatt ccccattaaa agcgacagct
     2401 agacctgtag cttctcctcc atgctcagaa agttctcctg aaaaaaagaa tggcaataga
     2461 aaaaagggaa gaataaagaa aagaagacaa cctagacacc ctttcttcat ttcttcctca
     2521 tcctttcttc gataatggtt tttggactgt tcgtcctttt ggtaaagtaa aatcagttcc
     2581 tggttttgcg tccaaaatcg gcagtgtttt aggatccttt tctatttttt ccgattgctc
     2641 tgttggctta tctaaagaag aaaatgcagg ttgtaacgat tttggtgcgg aaatcgacgg
     2701 tttactttca gacgaacgtt gccccggttg ttgcacagaa cgatttcctg atagagtggc
     2761 taccgacgaa ttaggaacag agtattggtt caataactgc tgcattgctg gataactccc
     2821 atttttcgcc tgatttttca cttggcgaat ctgttgtgaa agagaaccag cagctgttaa
     2881 ttgtggcacg ggtacttttc cagaaggcaa cggaatcgat tgaccaacaa aagcgatacc
     2941 tttatttaac aatggttttc tttgattatt cccttgttgc ttactcaatt gtgccaatga
     3001 ttgtacctgt tgttttggtc ttactgaatt catggacgaa tttggaatca aaccatttga
     3061 aagaccagaa ttccactctg ttttcgattt ggtagaagac atttcaggct ctaccccatg
     3121 ataacgaaca tgacgaccac tataaggcaa ggcttgattt gaacgcccac ctagttcaaa
     3181 gggattaacc acttgcctcc cttttaccga ttcttgtggt gtacgttttt gttgaaactt
     3241 ttgaaatcca tgtatcgctg cagaagcgag tggattcgtt gctcgataca cattccctgc
     3301 taatcctgca cctttgattg ccaaattttg tccagcagtt gatagttgac caggcagttg
     3361 tttcatttga gacaaagaat gacttgctat gtttttcgtg ttgtttatag tttgatctgc
     3421 agctcctaac cctagtttct ttaataaatc tttccgtttt acaatgagta aaattgatag
     3481 gagtgctttg acaaacatat ttcctaaaaa accaaaaaca gtattcattg gaattaaatc
     3541 gtctactatg ttatagatca aaaatgccac caaaataatc acactgtaaa aagatttttg
     3601 aaacatcaag cccaaaaagg actttaaggt attcatgagc atataatcaa atactggaac
     3661 aaaagaagcg agtaatgaaa aaggaatcac aagtaataaa cacaacacca acatttgaaa
     3721 gataaaacga atcatgccaa tcactacaag tggtaatcca atacttagat taagcaatgg
     3781 caccatagaa ccaacgactg ctttataaac agctttagtt ggttgaatat agacacgata
     3841 agccttcttt ttccctctat cttctcctgc agcagtggtc acttttgtct caatatcaga
     3901 taattcttca cttgacgctt ccttggctag aaattcttgt ggttcaatct ctgcttgata
     3961 caattcttct aaatttgttg tcccataatt taacaatata tacggatcaa caacagccgc
     4021 tttataataa agttggcgca ctttttgaat ggcttccttt tgtgtcgttg gcactaaaac
     4081 accattgaca tcttttgtcg ccaattcatc tagactattt gtagcagaaa aaataaagcc
     4141 ttctacctcc acggacaaat catttaaccc tttggtaaaa gcttctcctt tactaggtac
     4201 gttactacca tagccaaacc aaaccattga aaaaatgaca acgaagagaa atcgaataaa
     4261 caccattttt gcgtaatgtt tccctctaaa tatacgaaga gtaaatagat ataacacata
     4321 caagacgaca atccccgcac caataggatc gtatattttt gaataaatag tatccgaaaa
     4381 agtgaaaaac tggtgaatta actcgttcat tgcagctcct tcatagagct tctcaatgac
     4441 aaaatcaagg ccttgccaaa tcaatttact taaactaaag aacatattcg tcatcatttt
     4501 tagaaaatct gtgccatttg ccccaaataa cattttgcct aatgaaaatt cactatcaga
     4561 taaataagaa gaaaaggtat caatatgaaa tttcccaatc tcatagatcg attgatccac
     4621 ctgcttttct gccgcataca ccaatccacc aacaaaaagc agtccgaatc caatcgttaa
     4681 aaaaaacaaa acgcaccatt tcttttcctt atgctttata taagccattg tttcacctca
     4741 tttctattgc atgattaacg tatcctgttc ttctacttga gagtgacttg ttttttccgt
     4801 tgtttgtaat gcagcggtca tttcttcaaa caaactgtgt acattgagtt ttcctacacg
     4861 tccataggga tctaacatcc aacactgtcc tttaatcatg tggctcattt cagctaagtt
     4921 cgcttcattt acttccaaac gtaaatgatt caaaatcttt tctcgctcac tgtcttcatc
     4981 aaaagcaaag acgacaccaa aattcccttt ttctttatct gaacctaagt caccaataaa
     5041 ttgtgtatct aacactaatt gattcatctg ggaacgcccc acacgtgcca ttgctgcaat
     5101 aatactacgt cctgcgttcg aattattaaa tacccatgct tctgtaaaat aaatcgctgt
     5161 tttcttacta ctatctcgtt ttccaaacat ttcacaaaaa cgacctaaac taatcatcaa
     5221 acacaaagac tttcgatccg catctgtata tagttctggt cggacattgt catttggtaa
     5281 tttcaaatct tggatctcta aaatcgttgt tttggcatta aagtctaatc ccgggttttc
     5341 tccataagaa aatcctaaac gtaaaatcga atcttctacc gtcaagcgta aaaactcacc
     5401 atattctcga acctcttttt gttccatttg ttctaaatag tcgaccacat gcatcaagcc
     5461 aacttgttgt ccggcttctt tttgaactaa aacttcttgg attcccttta ataccgcccc
     5521 ttttaaaagg tgattggtac ctaacggact taactcatca atcatatcct gggctacttg
     5581 tttcgcatct actcgggata aacaaacaat tggatctaat acaccataat tacggggatt
     5641 tgtagcatct aacgtgacat aactcatttt ttgcaaatgt tctacaaaca aagggtaatg
     5701 tttctgataa tacgggtctt gaatgagttt cgtaaaccat ttgcgctttt ctcctttggg
     5761 atccacaaat aaactttgta cattcataaa cgaactatac aaaaagagca agccaactaa
     5821 aaaggtcttc cctttaccgg tttttccagt tactgctaca tgaggcgcat caaacaacgc
     5881 acctttgatt ccttccgcaa tggctagaag attcaaaaag acaaaacgat ttgacgcata
     5941 aattaattct tctaatggtg ttttttctcc tcgagaacca ccatccccta atgtatcttg
     6001 ccgaccaata taccagccgg attccatacc taattctgat actgctgaaa acaaccattc
     6061 gccaactgct tctacagttg ttcggtgctt ccaatgtaac tgccgtccca atggttgccc
     6121 taataaacat ttatagaaca attctcgttg atcatttttt gcacggtgga tatggataat
     6181 cgtatgaagt tgttgaataa ccgttgcact attttgacga acttcttcaa ccgtttgacc
     6241 gtatacaata aaacatgcga tccaatcgac gacaggttgc ccattatcta ctcgttgctt
     6301 taaatgtttt actaatcctc gaacagttaa taagcgttca ctaggttctt catcattttg
     6361 aaccaattcc ttatgctctg ttttgaaccg ttccgatagc caattcagtt ttaaaccaat
     6421 acctccctgt cctttcaagc gtggatagtg aattttcatt cgcaattctg ctgggaaaga
     6481 aagatcctga gcaaattgaa atagatcaca atttctcata ttttcaggtg tttccccaat
     6541 aggcaacaat gctaaataac tactccctaa ctcatcttct aattgaagaa ggcctttatg
     6601 ttccttcggt atacgtacat acgttccttg attgtctttc agtacttccc aattattttg
     6661 ttcttctact ttgtgagcca ttcctcgaat atattgcaga cgattgagat acaacagctc
     6721 tttttttact aagggacgaa tagaaaagct ataaagtaat tgtgtcactt cttttacata
     6781 aggatcactt tcagaaaaca aagtttccaa atcatctact tctaatccaa ataagcgtgc
     6841 taaacttcct gctaaatcta accagattag atttattaca tcatgaaaac tctccaccgt
     6901 tgctttttct ttgactttga ttcctaaaat aaatgaagga cgatagactt gaccttctcg
     6961 ttccaacaat gtcactgttt cttttgcata atacgcacca attgcttgac tatcgggaga
     7021 aaatcccttt cctaatgtgt caaacttcgt ccgtaaattc attgttcgtg gatacatcac
     7081 caactccaca tcttcataat ctgctaaaag caacagtaaa cgagccatca tttcttttat
     7141 ttcctgtgtc ttttttggtg tgttttttga aattgttcgt ggaaaaacat gatagtaggc
     7201 ccagatacaa tcctctccat ttaacaaaca atttttcttg aatgctttta ctggttcttt
     7261 tacaagcacc aatgaatttc acctcccaat aaaaaaggaa caaccagttg attgtccctt
     7321 tttctaatcc tctaaataaa catacttatt cacaaaaagt aattcttcca atgcattgtt
     7381 tgataccttg tcccagttat aatacacaca atcaccattc atcatacgaa tcatataaca
     7441 aaaccaatcc cataaataaa aatgcacttt ttttccatca ggttttagtt ttgccagtgc
     7501 taacacacat aaatagggga gtcctatata aaaaacaact cctgctggtg gaaaaaaaga
     7561 aatgacccaa ccaataaatg aacgtaaaaa taaatattca aagattacga ccaacaaaaa
     7621 agttgctgca ttgactaatg caactggaaa tggaagacgc caattgcttg taatctgttg
     7681 tacgcgataa ggttccgcat aaacaatcga ataatcataa ggttcccaat ccacttcact
     7741 atcctcctaa tccataaata atttttcaat gattttacca aacgcatcaa atacacgtgt
     7801 tggatcattt aagaagaaat aaactgcggc acctgctgcg atagatatta atgcatttcc
     7861 tacttttgat ttcataaaat ttcgcaatcc cagataaaca accaccatta ttaaaaaata
     7921 gccaccttgc gttaatataa aatctacaat tcccttcagt gtcatttccg ttcttctcct
     7981 ttcctatcca accaattatg tgttaatttt tcaacataat actgatttgt ttttttcgta
     8041 atgacaatcg tcatttgttc tttttgtaaa agtgacgtat caccatctcg aaagacgacc
     8101 gttgctttta caataaaagg ttttttcgtt tctttataac gcaatacttt catctctact
     8161 tgatcaactt tagctgtttg attgagtcct tcaggttctt tcatcatgta tgacatatct
     8221 tttgcattgt ttttcgcata cttatctaag aaatcttcca caaatccttc aacatctttc
     8281 gcttccgacg catcaaccgt ttcgtataat gtgtcatcat aagtaatcat tcgttgtttt
     8341 tctgtattct ttggtagtgc cgtaaaataa ggataagcaa taatacgaca gcccttgttt
     8401 gaaatagaaa agggaagatt gagtacttgt gtgattgtca cacttgtttc tttcttactc
     8461 tctggattca tcgagcgaat atcataagtt actttataac tagcagttgg aatggtttca
     8521 atttctttta atccaataaa cgaagcagca gttaattttc gaacacctga aacacttcct
     8581 ggttcttgaa taaagttttg tgcataaaac tcttttttta atgtttcttg acgttgttgt
     8641 tcttgttcat gattatcgaa tgtattcata tacaaagcaa caaaacgatt cataaaggat
     8701 tcaatttcag gtgtgtacgt taattctgac cgactttgta cttctttctt ttgtaattgt
     8761 tggatttcat ctttcaaaaa cgacacttga accttcgttt tcatggattg aaaaaatgcc
     8821 aagccccctg aaaaacaaag aaataaaacc aaacaccaaa tccatttcac tgcttttttt
     8881 gaatggattt tcttttgctt cggtactttc tctgtataaa ctttttcttt ccgccgtagt
     8941 tgtcgttttt tcataagcta ctccttctag tatgttttta ctagtacgta cgattgacaa
     9001 cgataagctt gtttttctga aaaatagtcc attcaattac cctcattttc tattcctttt
     9061 ctctttcttt tatatccaac aaatccagca atacttgtca acactcctcc tagaacagaa
     9121 agtgcaacat gtatttcttc accagtcttt ggtaagactt ttgtttttcc atctgctgtt
     9181 ttgatttcaa tattgccact tggaagtttc tttacaggaa tcgacaaatc ctttaccaaa
     9241 ttcccttcac tatcttggat taatggaata ccatctttta caccaacaat tgtttgatca
     9301 cctgctactt ttaatggggt ggttggtgtt ggaatatggg tcaattcctc tacattacta
     9361 gtgacaatcg gtacactcat tccttgagaa gtattcgtcg taatttcacc gcttggggtt
     9421 accgatactg tgacttcttt tgctggaaca ataggtttat tttcttttgg aattgcttct
     9481 gatttttcaa caggttgttt cggttcttct ttttgttctt cactggtaga cgacatcgtt
     9541 ggctgttccg tacttgacga atcagtattc ttttcagaag aactggttgt tcctgattgt
     9601 tccggagttg tgactatact tgaatccgtt gttgttgaac tatgcacacc ttcttcttcg
     9661 atcgaatcag tcggtaaagt tgattcagga aactctggtt ctggtgtcac tggctctttt
     9721 tcaggtttct ctgactgcaa ttgttcaggt tctgctggtt tttccgttgt tcctccattt
     9781 agctctgtct caacatctgg taatccttcc cctggcaatg tttctacaat ttctgactta
     9841 ggtgtttcta cagtttcatc tgcataaacc aatgaactcc ctaattgaaa cgaaaataat
     9901 gaaattccta gtgttgttac gactgctaat gttgtttttt tcatgattat tcctccaatt
     9961 ttttatgcaa ttcgtgtttt gttcatagac gccgcactaa tattatctga acgataaaag
    10021 aactcccgtc cgttttcttc taacccaaca tatggattat ttttgaataa ttgaatcaat
    10081 agttcactgg tgttgtattt tggatagttt gcaaaaaaat aatactgtgc ttgtcgccca
    10141 tccgaaaatt caacaagtaa ttcataacga taccgcttca atccttttcg ttgttttaaa
    10201 ggatctctat accaacttgt ccatcgttcc attcgtggat agagatagac acgatacaca
    10261 tagaacaatg ccataccaca taccaccaaa aataataatc gccacataaa aattccccct
    10321 tttcttctac ctttcttgaa tcatcgaaca ttcataccct ctatagagat ttgaaaaatc
    10381 catcatcaat tgttcatata aacgttgttg caaatagcga ttgtttcgaa tacataattc
    10441 ttcatagcca tcaatcactt gatcttcttt ttcatagcat cttgtagctc tatgacgctc
    10501 agcttgcaag acataaccaa actctgcacc atatcgttct actgttaata actgttgact
    10561 acgcaataat gcaatataac aatcacaaaa atgttcaacc gacatttgat ttttctcacg
    10621 tttgtgaaat aggtattctt tagaaagcac attattcgtt aaacaatctg ataaatagcg
    10681 ataatctggc ggtcggttat tttcatctgt gaatttttcc cataataaac tgatttttat
    10741 tcgttcagcg gctagatagt cttgttcgcg tggataaaat tcatcaatcg cacaaagttt
    10801 tttatcacct gaataaacaa atccatataa tgcgaaacga actcttcctt ttcaattggc
    10861 tctcctaaaa attccagtga cataccatct tctccttcct aaaaaaaata aaaaagcaga
    10921 aaccgatttg gcttctactt ttctttcctt ttatagctct tttttacgga agaatccgca
    10981 aatgacattt tttcaaaaaa tcaatcggca caagttcacg aaaacttgga gcaattttgg
    11041 atagaatcac ttccccatct tgtaaaatac aatcataaaa atcatcagtt acttgatact
    11101 tacgcttctt acaataattg ataaaatagt agcgatcatt ttctatttcc attcgttgtt
    11161 ctactaagcg catacgaaca tcatcataga aataagccac aaatcgccct tcaagttcat
    11221 gtttttcaat gggatactct tctggtaaca atctattttt tcgtcgttta tacattgctg
    11281 gataccttag aagaagttca tctaaacgtc tgtcagtata tggtaactga cgaatcaacg
    11341 attctaatcg ttctttatac agatagaata attggcgcaa gcaatagtgt accgcctctg
    11401 gattttctaa tactgttgga tcacgtgacc aatacgcacc aacataaatc ataatttttt
    11461 tcatttagac aatcacacca gcaatactaa tgaccgatcc acaataggta gaacaagtgg
    11521 catagcgacc aatttcctct aattctatct caatctcttc taaagaaaga tatgtctgtt
    11581 cttctgttgg ctggcgactc atttcccaag tgacagtcac caatgaaatt tcttccataa
    11641 gaggtttttc gctgctaagt gctgccacac agttttcata tatcttcatt ttatcgcagc
    11701 cttttttaac cgctaaaatc gcaggtattg gcaatgaaaa tcgataaaag cgaatgaatt
    11761 ctagccttcc tttccttcgg ctaaattcca actcttcgag ttcttgttcg tatcccttac
    11821 gaacttctaa taagcgtgca atttcttgcc agttctcttt ttcctgataa cgtccagctt
    11881 ttaccgcttg ttcaatataa ggaactcgaa aacgaaaata agacaaatca accatctttt
    11941 catttaatgc ttcgattgca gcctttaaat ccaacaggcg cagccattct gttgtcgtat
    12001 atgcattcat gcaattttcc ctcctgacgt tcccatccat tctagatagt tttgttgctc
    12061 gtcatttagt tcggcattat caatcccttc ttgtacaaag tctcttccta aaatacgatc
    12121 tgcttcttgt aacaacttta atgtcggagc tacttgtttc aaaaaccagc gttctgaacg
    12181 atctaatgag aatttttctg gctttactgt aaaatccaat tcttccatcg aacgaaataa
    12241 ttttgcccat cgtttatcaa caatccgtgc atcactttcc agtctatccc aaacaataag
    12301 ttttgcatta attaaaccaa cgccaatctc tcctaaacgt ttcggtgaat cacctaaaat
    12361 aaatgcttct actgcttgtg ttgctttctc attggctaac cgtaactcat atcgattata
    12421 aataccatat ttcgttaatg cttctaattc tgaaattttt tctcggttcg caatttcaaa
    12481 acgtttctca taaaaattaa aaaagagagg actctttcgc gatccaaaat acaaagataa
    12541 tccttcactt cgaaaatagc catcatctaa aaaacaaccg ccaatattct ggaatctctt
    12601 aaagtccatt tctaataaac ctgctttttg tttttctagt aattcaaaga gatcgaaatg
    12661 ttcttccgtt tccaatcccc aaagttcatc taacgcaata tcgaatcggc tacattgcac
    12721 acgtgtataa ccagcttcca actttccttg atttttccaa atggaatata gccatgttcg
    12781 ccaatctgtt tgttgttcac gcatgacttc ctcatattcc cggcaacctt gtcctgaaaa
    12841 ttgcacaagt acattttctg ttacagttcg ttttgaatgc cagaacaccc agatattccc
    12901 acgaacagaa agacagtcaa aaagatacaa gcccgttgga cgtgtttcaa attctgtcag
    12961 atccattcgt aatacacgtt gaatcactgt tttgtagtct gtcccaaaaa aggaaagacg
    13021 caaataatca atcattgctc gaagatctat tccgcttttc atatacaatc gaaagcgttc
    13081 cttgattcgt tgttcaaaat cctctgggat ttttcttttc ccttgttcca tctttctaat
    13141 gtaatctttt gagcagccca tcaattgcgc aaatcttgct tgtgatagcg gctttttatc
    13201 tccacttata ttatgaattg cacttaactt ctttctgtag ctttttagct caatcggtgt
    13261 cattttctcg ctccttttat aaaataacaa aatcgatttt ttttaaccct ttagaaacac
    13321 cgatatatca actagtcccc ctcgtttttt gggaaaagta gtacaactgc tgaccttaga
    13381 taatcacttg atacaaaagg gtttataaaa cttttttcta tgtgttatgt tatttctgcc
    13441 ccccatatta tatatcgggg ggctttacac aaagaggccg tgcgcaagcg cacgacctct
    13501 ttgtgagctg cacacgctgc tagcgagtgc gcattatagg cccatgcttc gcagccttaa
    13561 tgcgcaccgc caggcagagt gcggctacca gactacgtct agagccctcc cgatagataa
    13621 taactacaaa attaaatgat ctaattttgt tatttcacta tatttttcag gagaaaaaac
    13681 gcgataaatt gacaaagtta aatcctcttc taaatctact cgataatgat acaatcgagt
    13741 caatcgttct atatcttttt tcgttagcaa tacttgatta ataacttttc ctgtaaaaac
    13801 acgttctttg cgcaaaaagc ggtaatcagt tacttgttca atacgattca accaatcata
    13861 aaacgttctg gaagaaagag aaggattaat cattcgtatt gctgtagcta ctctataata
    13921 acaactctct gccatttaac ttcacctcct tagttgatta caaaatatgc gcatcagaaa
    13981 aacttgttcc ttttggatct tttgctaaat acatttggcg ctctagttgt tcttgtaaca
    14041 actgattatc atctcccatc gtttgatctt gactatcctc ttttactgta aaatcataga
    14101 caatcatttc agtaaatttc tcaaattctt tgataaagtg ataatctttg taaacaaatg
    14161 gcgcaaaaaa ctctacaggt acatcaaatc ctggaaaagc atatccacga ccaggttgat
    14221 ctttgttgta aaatggctta tttttaaaat cttctccaaa agtcattaaa taaccaatgg
    14281 gagacaatcg accaacagaa atacggaatg ttaaattatc ccgaacacca cttggaaaat
    14341 attctgcatc tggtcgttgc attgctaaaa taatgtacat ccctgcttga cgacccttta
    14401 atactaatgg ctgaatcaat ttatcgactc tatttctcgc ttccatatcc aacgaaccat
    14461 aaaaagctgc ccattcatca aaaaagataa aatgcggtgg taacccataa taagcataat
    14521 ttttccctgg ttcatattta ggatctttca tggttttcat ataggcatac cgttgattca
    14581 tttcttttaa tgcatttcgt aaacaaataa tcatttcttc atttattttg taaaacacat
    14641 gtcctttgaa tacatcgacg tcacctaatg ctgctaaatc tgccgctttt ccatcgcaaa
    14701 tatctactgt cccaacactt aaacaagctt gaattaaaga atacaataaa taggttttcc
    14761 caccaccgat tgcaccagca atcaacatat ttggtgattg atcatatacc caatccaaag
    14821 ttttcattaa atgaatacgt ccattttctg ctatacattg atcaatagga atccgaccag
    14881 aatctgaaag gaatacataa ttgattcggg ctttttctcg ttcttcacga attaaatcac
    14941 gcaaaaatac ttcagataac aaatgaccca tttttaaaaa tcgttcgtga aaacgcccac
    15001 catctaaagg aaaagaaacc actaattctt gtttcttttg ataaaaataa acttttggta
    15061 atctcatttt ttcccttgtt tgtttctcac taacttgttt ctttgtataa acaaaccgat
    15121 tgtcaattaa cattcgaaca agtaactgac gccaataaac agaggcaaaa tatccttctt
    15181 ttagtcgcga ccaatgcatc aaccctaaaa ttaacccact aaccagcaac aaatacaaca
    15241 caatacttat tccaggaata agatacattt gccaattcga aaacgtactt aaacgtggat
    15301 aaaatacttt ccaactaaac caacctaaca gaatcaaaaa tggaaacaaa aagaaaccat
    15361 aatagcaaaa ccataaataa cgattgaaat agcgaattcg ccgaccacga tacttgaaaa
    15421 aatgagcttt caattgtcac attcctcctt tctgttttta cttttcctgt gctaaaaact
    15481 tttgacaaaa agcaactaat acaggaatat cacatttagt aaaaaaacat aatcgaaaaa
    15541 gatttaatcg atttttataa gggtgtgcac acatattaca tattcgtact atacgaatcc
    15601 aaatcacttc ctgatgatct tgtttccact ggtacggtaa tgaaaaacga acaagatcac
    15661 gtaaaaacat acactgccca ataaccgcac aaatatatgc atttgtttgt acaaaaatcg
    15721 ttggattgtc tccaaaatac tcaatcaatt gttggatatt ttgataacaa gcacaatctc
    15781 tcaaagtatt tgattggttt tatctgaatt caaaatctcc ccttccttct atcttagata
    15841 aaaagaatag gaagactcct tcctattctt tcaaaaaaac cttatttttt ctctttttcc
    15901 ttagaatcaa cacttggttg tttttgatct aaaccttttt cttgtgattg tttcatatta
    15961 ggattatttg ttggagcttc tactttctct aatcctttcg cataaatcac taaatctgaa
    16021 tattcacgat tgccatcttg tgctggaata tataccacat gatattctgg atcaattaat
    16081 ttcacaggat cacgtcgttt aaaaccagtc aaatctacat ctgctggaaa tttaactcgt
    16141 cgtgcaatct ttggttcatc tggatttcca aaaactaatt gtgctcgctg tgatcgaatt
    16201 tctcccgtat aatcgcctgt ttcattatca aatacacgat cagactcttc taatgcgcca
    16261 aagcgtacgg ctcctaaaca agtttcatct aatgcttctg taatgtcata attatttgga
    16321 aattttaatc ccatcttaca aaacctcccc aatttttaca ccagttaaaa agacaccaac
    16381 atcttgatag ccagttgttc gacgctctgt ttgtcccata tcatttgttt cacgactatt
    16441 cactcgttct ttacgaaaaa caaaataagc ttcttcaaat gaaatacgca cctctttttc
    16501 tggtaatcgt aatcttttat cctcttcagc tgtgagataa acaaaaaaag caggctgttc
    16561 ttctcgcgaa cactctgctt gtaattgaac atatcgccca gacacaccat taatttcctt
    16621 tggtggatta ggttcccgtg aacccaataa aaatacttga cctaaaaact ctttcttcat
    16681 acgcaatgct ttttctgcca taaagttttt cctcctctta aaaaccaaaa taaattctaa
    16741 atatttctac attacaatca aacaagcggt taaaaatcct aaccgcttgt tcctcatgac
    16801 taatctttgg ctttacgtac tttataaagt gttataccta aagcaatgac taatactact
    16861 aatccaagaa ccataagtat actacttgtt tgttcacctg tttttggcaa cattggtaca
    16921 acagtagctg gtttaacccg ttgttctggt ttcactggtt gcggtggttt tggcgcttcc
    16981 acaatttgaa ccgtttgatc tttgtttgtt agatctacat tgtgtttcgc cacttcttca
    17041 aacgtttctt tctcatcttc cgttttcgct tggagccatt ccgcaaaact caagcctttt
    17101 cctgcaagat tgcgaccgtc cactaagaat tcaaataaga attccatcat ttctttatcg
    17161 gccgcaaaga ctttttccgc atgagtgcct tcaaatggtg tgccgtctgg tgttaagtag
    17221 ccttgaacaa ttaagcgata gatttgacca atcgcaagac cgtctacttt gacccattca
    17281 agcacagttt gatttggcaa ggccaagatc tcttttccgc catttttatt cgtcgctttc
    17341 gtcgtaatgg ttggattact gattttgatg gtttggtcat tgtcggtaat atctgcgtga
    17401 gaagccaata atacgccttc tctaaacaga tcttcaaaga ccacgacttc tttgcctcgc
    17461 aacgcacgtg cgtctagaat aaagtctaga ttgactgtac catccgttgt ttctgccaca
    17521 aacgttaagg tacttgtgac ttcttttcca tctactagca ctggtttttc cgttactttg
    17581 tccattagaa caccgttgac tgtgtatgtt tttccaacga ccaaatcgtg gtatttcaca
    17641 gcgtctgtaa tggtgacttt cgttaatgga ttaacctctt tcaagccagt gggtttatgt
    17701 gtagccgttg tacgtacact tgggttagtt actcgtaccg tttgcccttt gtcgttgatg
    17761 tctttatggt ttgctagttc ttcatcattt ctaaaaagac tttcaaacac gacgatttca
    17821 cgaccattta tacctgtcaa atcaaaggta aatggtacga tcaccgtttc attttctgct
    17881 ttggcaataa agccaacact cgtttctacc gtatttccat gcacaagcaa gggttcaccg
    17941 gttgctttat ccattaagat ccctttgacc aagtatgctt ttcctggaag aatctcggta
    18001 atttcaacgg tatcgtttaa ggtaaacaat cctgttgggt ctgcgactgt caatccgtct
    18061 tcaaagacag ccgtggtatg aacggttgga ttattcactt tcacactttg ggcttcatcg
    18121 ttgatatccg catgtgctgc aacttcaatg ccatcacgga aaagtttttc aaaaacaacg
    18181 atcgtttgac ctttcagaac actagcatta accacaaatt caaggtcttt tgtgccattg
    18241 actttgtctg caataaaggc caaggtactt gtgatttctt tgccatcttg taaaattggc
    18301 gcattcgttg ccttgttcat caatactcct gaaatggtgt attcttttcc gacaaacaag
    18361 ttggtataag aaacactgtc tttaatgacg atcgtttcta atggatcaac cactttttca
    18421 ccatcggctt tatttgacgc ttgtgtttct agttttggtg gaatcaagta attacgtaca
    18481 gaaaccacta acgtttcccc atcatctggc gcattttgtt tgaatgcaac cgtgaatgct
    18541 tgtttatctg tatttggttg gaaactttct aatggggcat tttccaagaa gtaatagtca
    18601 tcggcaacta gacctttcac taaaatttcc ccgttttgat cagtggtata ttcaccaatt
    18661 gcttgatttt taccgttata caaggtaaag ttcacacctg cgagcggcgt tttcttcttg
    18721 ttccattctt catacttgaa taattttaca cttttccgtg cttgacggtt cgcaaaatgg
    18781 atcactttga tcggttctgt atcattggta atcgagaaca ctaatgggtt ttgattcaaa
    18841 acgtaattta cgggggcttt gatttcttcc aaacgatagc gatcttttcc ataagtaagt
    18901 gtaccgttag ttaggaaaaa gcctttttca ttggttttaa agatatccgt tgtttctgta
    18961 tcatttggaa tctccattgt gacataacga ttggctaaag tatcaaaaat cttgaattct
    19021 gtattagcaa gtggaatcac ttttcctgtt tcttgatcca ctttcaccac tttaagacgt
    19081 tgttcaatta ctttatcttc taaaacataa tggaaagttt gcccattttc agaaattgtg
    19141 acttcaagtg gttcaaatag tttataccct tcttttcctt tggtttcaga aagaatgtac
    19201 gtatcaaaga caacggtatt tttaccaaaa gtagcataac catcattgtc tgtcacaacg
    19261 gttttcacca ctttgccagt tgtttttgac gtcaaagtga tttcaatgcc agctaatttt
    19321 ggtttgttat ctggattcgt tgaatcgact aaatctttat tagcaacttt cactaaatca
    19381 atggttcctt tgatcacttg atcttttgcg gtcgcattga cagtttttcc aggttcaaca
    19441 acaatttcaa ttgcttcatc agaaagcaca taaccttttg gcgctttgat ttcttttaaa
    19501 acatatttgc caggatcaag atctttaatt tctgcctgta ctttgccgtt aatttttttc
    19561 aaggtaattt ctttaatctt tttcccatct gcttgataca aaccatagac cgcattttct
    19621 aaagaagctg caccttgtgc tttcacacca gtttccgcat cttctttaaa cacacgaatg
    19681 tttccttgtt ttagaatttg taaattaata acagacgcat taggttctgt tggatgtaac
    19741 acaccaattg tttgagctcc tggacgacga taggctaatg gcgcaccttg aactttaatt
    19801 ttattcaatt gaatttttgc tttatccggt gcctcttttg tgactgtaat ccatacttca
    19861 ttgccgtgaa tagatacatt gacacctttt ggtttttgaa tgtctttcac atatttcaaa
    19921 aaatcatttt tattctttac tttcaacgtt tcgccaattt ttaccgtatg tgtttgatta
    19981 ttaaaagttg ctttttcacc aaagttatta atcaaacgtt gaatttctgc ttttcgacga
    20041 tcataatcaa cacggatatt tttgattggg atttttgtgc ccaaagcttc ccaaatcata
    20101 aattgtgccg caatgtattg ttcatcggat ttgtctttat ttgtgacata tcctaaataa
    20161 gagatcaagc ttgttttttt ccgtacattt gaatttttca aatagttttt caaagcagta
    20221 gctgtataaa cttgaccttc tgcggctgag acaccaggct caatacaaaa cgccacttgt
    20281 ccattaatct caaaacgaac catataattt aaagtgaagt ttagattgtt cggactagaa
    20341 gtaacaccaa tattttcgcc ccaatcaatt ttccgaccac ctaaaacagc tgcattggtt
    20401 gcacggcgaa cacgaaccga acgattggtt ggtactgtta ctaacagtgt aggtgtacct
    20461 gtttttggaa tgttctgctc ttttttcttt tgattttcaa tactagccgt agattctttg
    20521 tttggtttcg ttggttgatt ttgactagct gcggttgaag agattgtttt ttcaacgttt
    20581 tcctcatttt ttccttcttt gtcagcagta gccgctggtt gttccactgt ttcttctatt
    20641 cgtttctttt cttccgcttg tttctcagaa gactctggct gcacagaagg cgttgcttcg
    20701 gcagcttttt ctccttctag agtggacgtt tctgaagcag gggttgtaat tgaggcagtt
    20761 tcttcaactg gttgtgaagt accaggacta ttccctgggt gttgtgtttc cccaatcgtc
    20821 tgatcgagag tcgttttgga attgaccgtt ggcgcttctg tcacaggggc ctgttcaaca
    20881 gtggcttcac cagctgggac cccggcttct gctggttgga cttctgtcac ttcagaagcg
    20941 acttgggcaa tggcttccat cgtaggttgt atagccgtcg tttcttctgc atgtgcttga
    21001 gcagttccca ccaagaaaca gaattgagaa aaagccacca atgcgagtgc tttcaaccaa
    21061 ttcattttcg tttttgcata cacaagaatt cctccttttc ctgagaattt tatataataa
    21121 aacaaaacgc cgttaccaaa agtgataacg acgtgaactg tctcttctat ttttatctgg
    21181 cgctcttatc tgaacacatt tcatcaatga ttttaccctc ccactataat tacagaacaa
    21241 aaaaagaacc tgcttcgtgg aaatcaactg tccatttccc aattggaata ccagcttttt
    21301 tggcaacttc accatcacca aatctcatgc cataccaatt actaccttca tccttaattt
    21361 ctttccaacc atatgacata gcttcatcta atgaatcaaa aatcatgaca ctattgccaa
    21421 ttgttacagg atctggctta agatcttctg gaagagaaat atcaatcata ccataatgat
    21481 ccgattcctc agtattattg tcattactag ctactggttt ggttgttcta ctggcttatt
    21541 ttgatacaac aagtactctt attcttcttt tacttctccg ttttcaattt cccattcaaa
    21601 ccactccgca aagtcttgct taaaaccatc tactcgatac ctattttgta aataggcatc
    21661 ttctgacgtc gtaggatcta aataggtagg tttattctct ggacgagcat agacacctac
    21721 ccatgtttcg taatctcctt caaaataact atctaccaaa tagccttttt ttctaagaat
    21781 ctcccgaact tgatttttaa ttattgatac ttgttcaaaa ccatcactca ttctatcacc
    21841 tcaaataact ctagattctc ataaatattc ccgacaattt caatcctatc aatgatctct
    21901 aacaaatcgc tacttatgct tccccattcg tataagaatt tcccttccgc aaaataaatt
    21961 ttccataaac ttcttcatga tcgtcccaac caatatcact ctcgaaaaat tccacgttgt
    22021 tcttatcttt tagctcagta aatgccataa gttcaacatg ttttccaacc tcgaaacaat
    22081 cacaccaccc atcaaccgtt acacgtgtgc cttcaatacc taagaaactt tgtcctcgtg
    22141 tattaaacac taaaactttc cgcatttttt gctcattaat taatcacgcg cgaaatctag
    22201 gaatcacaac ttattcgctt cttctttata aataaaaaaa ctccaataat cggaaattac
    22261 tatcttttcc tcattccttt tttaaatctt catacttctt cttatctttg tcctaaccta
    22321 ataacacaaa ttttgaagaa aaactcagta aaacctgatt ctttttttat cttcacaaca
    22381 accaactttt tcttcagatc cttttactag aacttgtata caaaaattgt tgaatgctga
    22441 tataatttgc ggctacttga aaaaacgata gatgtaaaaa gataaataga atcatttttt
    22501 attctatatc agtctatgat tcattgctta tcaatcaccc aacccattcg atgccgtttt
    22561 ttttagagaa atttaaaaaa gaccgtacga atctcgcatt atccgattac ttttccagaa
    22621 aagatcccca attctgtata aataacccta tcttcttgtt ggtttcattt tctcatataa
    22681 gaattcagtc aatctaccca ctatgaccat tactacgtcc aacacaactg acatattaac
    22741 cacgtaagta ttccctcaca gatctccgaa tctccatggt atggattccc atcctgacgc
    22801 tgcagaggac aacatatttc atgtggctct gtaccctttt gatttggaaa cactacaaat
    22861 caatactcat ctataactta tcaagcgaac tttcgctagg cttctagtga ttactaaatt
    22921 gttggataac atacatagcc cattttatct agctgttatt cataacagtt agttcttgta
    22981 ttacttcttc cgcttgtgtt gccattgagc ttgtcaaaaa gttacttaga aaaaagctgc
    23041 cagtaaagca actttcaaca aacccttttt gtttcttatc atatcaagaa acctcctttt
    23101 ataaattttt tctataataa aaaacgtcga taacttaata agtatcgacg taaactattt
    23161 ttatatcccg taaatcaaaa attctaaaga aagatttcct atataagcat attggataat
    23221 tcgattagta ttgggtatat ctctaccatt ctcataccta tctatggacc attttgaaat
    23281 tgaaggagaa aaaagctttc caaactcctc cctttctaga taataatctt tcctaatttt
    23341 cctcatcctt aatcccatac taaaagaatt tatcttttta aaatcgctaa ctctttcatc
    23401 ttttggaagt atattcttat aatcttctcc gtacataagg taaggaacag tgaccttacc
    23461 aagataggca atattcatta gtttttcaat atctggaata ttaatacctt tttcccatct
    23521 acttataaca tttttgcctg tatagatggt aaagttttta ccaaattttt caagcgtctc
    23581 ttcccggttc tttcggactt ctcgtattct ttttcccata acaattttat cgtcttttga
    23641 taaactaaat atctcactat cacgattaat ctccttcaaa atttcttttt cattacttaa
    23701 tagaaaaata tcgatttttt ttgcatttct tttgacggat ttctctttct atttaacaca
    23761 taactgagta atacttcact aattcctata ttatcagcta actctttgtt aagtaactta
    23821 ttcatatctc tgtatgcaat tagtttaccg atgagaatct caatcttatc ttcctcatct
    23881 tttattagag tttctatatt cagaatcttg cttagagtat tatctacgtc tttagggatt
    23941 tttcttgacc ctttttcata tttaactaaa gtactttgtg aaatacctgc taaatcagct
    24001 aacttttttt gagatagttt tttctctttt cttagagatt taagaaccct tccacttgaa
    24061 ttatcaacca tgaaaaaagc acctcctatg agatgctttc atcatatact gacagctaaa
    24121 aatcttcaag aaaaatattc caattttgtt aattttagta tcgccgtgat aaccaaatga
    24181 cagtttaaaa tcttttatac agataatcct cagtgttgca tctactcaaa aaggtttatt
    24241 taataggttt ttcgattgat tataagttat ttcacactat cttgctcatc cattttcaga
    24301 acggccatga aggcttcttg cggaacttcg acggagccga tttgtttcat ccgcttcttc
    24361 ccttcttttt gtttctctaa gagtttacgt ttacgagaaa catctccacc ataacattta
    24421 gccaagacgt ttttacgcaa ggctttgatg tctgaacggg caacgatttt ttgtccaata
    24481 gctgcttgga ttggcacctc aaattgttgg cgtgggatta gttttttcag tttttcaacg
    24541 attgcttttc cacgttcata ggcaaagtct cggtgaacga taaagcttaa tgcatcgact
    24601 ttttctccat tcagcaagat gtccatcttc actaacttgc ttttttgata accagacatt
    24661 tcataatcca atgaggcata gcctttcgtg cttgatttca atttgtcgaa aaagtcaaag
    24721 acaatttcag aaagcggaat attatagacg acatttactc ggtaatcatc taaataatcc
    24781 atcgtaatga attctccccg ttttcgttga gaaagttcca ttactgcacc gacaaaatca
    24841 tttgggacca tgatctgtgc tttgacgaat ggttcttcta catcctgaat cgttacaggt
    24901 tcaggaaaat ctgccgggtt atctactgta gcagtcgtac catccgtttt attaacatgg
    24961 taaataacgg atggtgcagt cgtgatcaat tctagattga attcccgttc caagcgttct
    25021 tggacgacat ccatatgaag aagtccgagg aatccacagc ggaacccaaa acctaatgct
    25081 tgagaggttt ctggttcgaa ttgtaaagca gcatcattca attgcagttt ttctaaagct
    25141 tcccgcaaat cgttgtaacg agaagtatca attggataaa gaccacaata aaccatcgga
    25201 ttcatttttc ggtaacctgg taaagcttca gcggcaggat tgtctgctaa cgttactgta
    25261 tcccctactc gtgtatcttg gacagttttg atacttgctg tgatataacc gacatcaccg
    25321 accatcaaaa agtctctagc aactgctttt ggcgagaaga ccccgacctc tgtaacatca
    25381 aatgttttgc cattactcat cagtttgatt ttgtctccgg gtttgaccat accgtccgtg
    25441 atccggacat ttagaacaac accgcggtaa ctatcataaa tagagtcaaa gatcaaagct
    25501 tttagcggtg catctaagtc tccacttggt gcaggaacat attccacgat ctgctcgaga
    25561 atatcttcaa tcccaatccc tgatttggca ctggctaata cagcttcact agcatcgatt
    25621 ccgattacgt cttcgatttc ttgacggaca cgttcgggat ctgctgcggg taggtcgatt
    25681 ttattgatga ctggcaggat ctccaaatca ttgtctaacg ctaaataaac attggccaat
    25741 gtttgtgctt cgattccttg tgctgcatcg accactaaaa cggcaccctc acaggcagca
    25801 aggcttcgag agacttcata ggtgaagtcg acgtgccctg gggtgtcaat caagtgaaag
    25861 atatatgttt ctccattttt cgctgtgtaa ttgagttcta cagcatttaa tttaatcgtg
    25921 attccacgtt cacgttccaa atccatcgag tctaacagct gatcttgcat ttcgcgagac
    25981 gtcacagtgt gcgtcatttc taaaatacga tcggccaatg tagatttccc atggtcgata
    26041 tgagcgatga tcgaaaaatt acgaatctgc tcttggcgtt ctttcatttt ctttatatcc
    26101 atagcgtctc ctcttttcat ataatcagca ctttccatta taccaacgaa aagcagtaat
    26161 ttaaagagtt tttaattagt cagctataga agtttttttt gtagaatttt gctatactgt
    26221 tatcaagcta ataaatggag atgaaaaaat ggatcaaaaa gattttagag aaaatcttga
    26281 attaaaaccg gtcactcaag aacatatcga tcaattcaat gaattgcttt cctatgtgtt
    26341 ccaagtgact gaagcagaca tcgaggaaag cgggtttgag aataaacgag cttttatccg
    26401 ttccaaaaaa ccgattttgg aagtatcgaa agtgttcgga tggttccacg aaaataaact
    26461 gatctctcaa atcgctatct atccttgtga agtcaatatt cacggtgcac gttataaaat
    26521 gggtggtgtg actggagttg gaacttatcc agaatatgct aaccatggat tgatgcaaga
    26581 tctaattatc gttgcattgg ataatatgcg caagaataag caatggatct cttatttgta
    26641 tccttacagt atcccctact atcggcgtaa aggatgggaa atcatgtctg ataaactttc
    26701 ctttaaaatc agagatacac agctacctaa acaaatccca gtaagtggta tggttgagcg
    26761 attaccagtt gatcatccag acgtattttc cgtttatgac aaatttgccc aacaaaacca
    26821 tggtgcttta ttccgcagtg attttcattg ggaagagtat tggcgtttcg aaaatgaaga
    26881 tgagcgcaca gccgctgtct actacgatag caaccatgaa ccaagaggtg ttctgttcta
    26941 ctgggtagct gaagaaatat ttcacgtaaa agaaatgttc tatcttgatc aagaagctcg
    27001 aaatggctta tggaacttta tttccgcaca tttttccatg atctactggg tacatggaga
    27061 tatttataaa aatgagcctt tagcattttt gattgaagat agtcagatca aagagcagat
    27121 cgaaccatat tttatggctc ggatcgttga tgtaaaagaa ttccttcaac ggtttccgtt
    27181 tgttggaaca gctgatgctt ttcatttcat cattgaagat cctgtcgctc cttggaataa
    27241 tggtgtcttc gctttaacat gggatgaaca gggacaagtc cgtgtcttaa atgaacctat
    27301 aggaaaatcc gttcgactgg atatccaaac attgacttgc ttgatgatga attatcgccg
    27361 tgcttcttat ttggcaagaa tcgaacggtt agaaacagat gaagaaacac tgaagtcact
    27421 agagcgtatc attccaaaca tggaagctta ctttagcgat tatttttgat aaaaaggatg
    27481 atgtttagat gaaaatttat tttgccgcac caatgtttgc taaaagtgat ttgttatata
    27541 accaacagtt agttaaagaa atcagagagc tctcttctga gctttcgatc tatcttcctc
    27601 aagaaaatga agcaatcaat gacaaaactg cttatgcaga cagtcgaatg attgctcttg
    27661 ctgacacaga aaaagtgttg gctagtgatt taatgattgc tttactagat gggctgacga
    27721 tcgatgccgg ggtagcatcg gaaatcggtg tggcttatgc gaaaggcatc ccagtgatcg
    27781 gcttatatac tgatactcga cagcaaggcg gaacccaccc gaaaaaaatc gctgcactac
    27841 aagaaacagc tgaaaatcaa tttcactacc tgaacttata tacaataggt ttgatcaaat
    27901 tgaacggaaa agtggtttct tcagaaattg agttgctttc agaagtaaaa agatttttag
    27961 atggagggac tttcagtgat taaagaaatc aaaaaggtgc aaatagcttt acttgctttt
    28021 ggtgtattcg ttgtctgcta taatttttat gaatttatca cacaaaaata ttcgacttct
    28081 caaggaatca catttatcgt ggaatcttta ttagggattg cattgatttt catgccacaa
    28141 gtcattttga aagttttcaa acttaaaata ccagcagcaa tcgttttgtt ttactggttt
    28201 ttcttgttca tctctgtctt tttaggcaca gggatgcatt tgatcagtat catctctttt
    28261 tgggacaaaa tcttacatgc ggtgagtcca atggtcctga cagctcttgg ctatggattg
    28321 attggttact tgatgaaaga tgctgagata tcaaaaacca gtccttggtt gttcctctta
    28381 ttcggctttg cgtttgctgg actttgcggc gtgttttggg agttctggga attcttatgc
    28441 gaccagttct taggcatgaa tcttcaacgt tttgctgctt ctgatggcac actgtttgtc
    28501 ggacgagcag cattgatgga tacgatgggc gacttgctga caaatacgat aggtgctgcc
    28561 ttaatgggat tgtttgcatg gtctcaaagt aaaaaagatg agcgttactt tgaaagttat
    28621 aaattagaaa aagtgaaaaa tacctaataa aagaggttgt gacagaagcg ggcagcttca
    28681 agaaatttcg gcttattttt cgaagaaact acttctggaa cactgtttat ttgaaaaaag
    28741 gaggtctgac actagttgtg tcagacccct tttttctttt atagtctcaa tggaagatta
    28801 gacgatttct tctagctctt ctgttttgaa atgaagttgt ccatcaagta aagtaatcgt
    28861 tacttttgat ttaggcataa catgtcctgc aacgatttct ttagctagtg gtgtttctac
    28921 ttccttagtg ataaatcgtt tcaatggtct tgcaccatat gctggttcat aagcattttc
    28981 agcaatccac gttttggctt catcactgat tgtcagcagg atttcttgat gttccagacg
    29041 ttgtgccaat tgcgccacca ttttgtcaac gattcctttc acgttgtcta ggctcaatgg
    29101 tgtaaataaa atcgtgtcgt cgattcggtt caagaattct ggtttgaagt ttccacgtaa
    29161 tagcgtgttg acttgttcag ccactgcttc tggaatcgtt ccatcagcag tcacgccttc
    29221 cagcagtaac tgtgaaccga tattgctggt catgatcaga accgtatttt tgaaatctac
    29281 tactcgccct tttgaatcag tcaagcgtcc gtcatctagg acttgtaaca agatattgaa
    29341 gacatcggga tgcgcttttt cgatttcatc caacaagacg attgtataag gatttcgtct
    29401 gacagcttcc gttaattgac caccttcttc gtaacctaca tagcctggag gagctccgac
    29461 tagacgagac acagcatgtt tttccatata ttcactcata tcgatccgta ccatatgatc
    29521 ttctgagtca aacaagttct cagctaacgc tttcgctaat tcggtttttc cgacaccagt
    29581 tggtcctagg aaaaggaaag aacctagagg acgatttggg tcttgcaatc cagcccgtga
    29641 acgaattacc gcgtcactga ccgcatcaac tgcttcatct tgaccaatca ctcgtttatg
    29701 aagtgtttca ttcaatttaa ttagtttttc tcgttcacct tctacaagtt tcgttacggg
    29761 gatacccgtt aatctgccaa cgacttgagc aatctcattt tcggtaacgg actcttgaac
    29821 catcttaatc tcgctgtctt ttgctttagc ttctaattcc ttcaattctt tttctaattg
    29881 aggtatcgta ccatgacgca atacagcagc gcgttctaaa tcatagttat tttctgcatc
    29941 ttctaattcg tgttttgctt tatcgatttc agcacgtttt gctgaaacag aattgacttc
    30001 ttctttttct gtttcccact gcatcttcat cgcatttgct tcttcacgaa gttcagctaa
    30061 ttcttcttgc aaatttttca agcgtttttt acttgcatca tctgattctt ttttcagtgc
    30121 agcttcttcg atttccaact gcatcaaacg tctagtaact tgatctaatt ccgttggcat
    30181 agagttcatt tctacccgaa tcgttgcact ggcttcatcg atcaaatcga ttgctttgtc
    30241 cggtaagaac cgatcagtaa tataacggtc agataaagta gctgctgcta ctaatgcgtt
    30301 gtcatggatg ttaacaccat ggtggatctc aaaacgttct tttaatccac gcagaatact
    30361 gatcgtatct tccactgttg gttctttgac taataccttt tgaaagcgac gttccaacgc
    30421 tttgtctttt tccatatatt gacggtactc atctaaagtt gtggcaccga tcaaatgtaa
    30481 ttcaccgcga gcaagcattg gtttcaacag atttccggca tccatacttc cttctgtttt
    30541 tcctgcccct acgatattgt ggatttcatc gatgaacaag aggatacgtc catcactttt
    30601 tttgacttct ttcaagactg cttttagtct ttcttcaaat tcaccacgga attttgctcc
    30661 agcgatcaat gcacccatat ctaatgaaaa aatcgtttta tcttttaaat tttcaggcac
    30721 atctttgcgt acgatacgtt gagcaagccc ttcaacgatt gccgttttcc ctacaccggg
    30781 ttctcctatc agaacaggat tattttttgt ttttcgtgaa agaatacgga tgacatcacg
    30841 gatttcttca tcacgaccga tgattggatc catttttccg cttttgactt gctgtactaa
    30901 atcaacgccg tatttttcta atgctttgta ttgttcttct tggttttgtg aggtcactct
    30961 ttctcctcct ctcatctctt cgatgttttt acgcaattct ttttcagata atccgttttt
    31021 attcaaataa acagttaacg gataattttt taatttcatc aacgctaaaa taacgacttc
    31081 cgttgaaaga aactcgtcgc cgaagctttc acgtatttgg tctgcttcat tcaataatcg
    31141 aaagaaattc tggctgaggt tttgtccata ttggacgttt ccaccagaaa caactggata
    31201 ctcatccagt agacgatcaa tttcatgttc aaaagattcg acatccaatc cggcatccgt
    31261 atagaaattt cgaccaaaat gattagattg taaaaagatt ttccatacat gggcaatgtc
    31321 gatatcttga tgttttcgag tgaccgcaat ctgttgagct tcagcaatcg cttcttgaag
    31381 cgtcgtagtc attttctcaa tattcataca ggtataccct cctaattaaa ggtaagatca
    31441 cttatttctt tgatctttac aaaaactatt atatcgcttt ggtcaatttt ggtcaaaata
    31501 tacacatagt tttttgactt tttttctcga cttatataaa tcttaaaaaa acaaaattga
    31561 ttgtatgtat ataaaaaaag agccaaacaa acgtaaaatt atcttatcca taacgttttt
    31621 ctttgatttg ataaaaaggg tagatcttat aaaagaccta cccttgattt tctttattct
    31681 ctttttttac ttctattatt tcttctttga tcactcttcg ccgttcagca atcacataca
    31741 caaatccata gagaaatggc aagataaagg aactgaaacg atacagtaaa agcgaagaaa
    31801 ctgcgtcaac tgttccaaca actggtctga ataataacaa atagacaaat tcaaaggaac
    31861 caataccagc aggcgtagga ataacccctg aaagcactac tgcaaagctg ataaacgaaa
    31921 tggtcagtag aaaatctatt ttaggatggt tttcaatcag aatcaaataa ggaagtacat
    31981 accaaaatac aagttttaac atattccata gataaatccg caatagcgca gtcctgtctt
    32041 ggataatggt ttggaccgtt tcccttaaag agtagatctg ctgattgcat gtatccaccc
    32101 atttccgcaa acgctcactt ttaaataact tattcgataa gctgacaaaa aatatttgaa
    32161 cattcaagct gacggacatc gccaataaaa aggcaacaat cacgatcgtc aaaaggatac
    32221 cagcgatgat aaaccagatc attgatggac cattagaata aaaaagagag aattggatga
    32281 ccaagccagc taatgcataa gtgatcactg ccagtttgta cataatcata tggagtgctg
    32341 tcacccctgc tccctgggat agcttcattc cttttttgtt ataaaaataa atctccgaga
    32401 tcagcgttcc tgtaccaaac gaaacgattc ggtaaaacgc aatatagcta gaggtcaaga
    32461 acccatcttt cgttgtaaaa ttcggcgcga aaggttcagc aatttctttg attgagcgcc
    32521 cttcagcgat ttggtaaact gtccctaata taacagccgc tgccaaaaca acaacactgg
    32581 tagacagcaa ttcggcaaag atatctgcaa atgattgatt gattaaataa taaataatgg
    32641 caaaaatcac aatcagcaaa agcagattca gaatgatttt agttttcgtt cctttagacg
    32701 acatctcctg ctccttaatg gaaaaaataa atgagaatca aatcaacaag tacacctgca
    32761 gcgaatccta tagtaaactt ctttttccga gttttatgat ggaaaacttt tcgagagatc
    32821 aatcctccca aaccaccgcc taacaggctg acaaatatca aattattctc aggaacacgc
    32881 cagccgctag ttctagcctg atgtttatca taccccatca gacaaaataa gtaaaaattc
    32941 acaatgaaaa ggtaaaacca caaaggattg tgtaacaata catccattac tcttcttcca
    33001 actttctgtt aactactatt tctaagcttt ttcttctttc tttggtgaat aaactgttaa
    33061 tccttttgat acaacagata attcaactgg aagatcatct gtcgtgtctc catccgttcg
    33121 agtgcccaca gatttttcct gcgcttggat tttcatgcgt ttggctgtga aataagtaat
    33181 gccggggatc gtatagaatt tgcctctcat gattctaggc aaataaaaaa taaatcggaa
    33241 aatatctaag gaaggtacga tcgttacatg aaattttcca tcatctaggg tcgctgagtc
    33301 gtcaaaattt gtaaaaccgc ccacggagtt agacatcgtg actgtcaaca gttgggattt
    33361 tcctttccaa tgctcctcgt ctgtttctaa atccaaatga tattttttct tcttcagcaa
    33421 taacttaaaa aacttcttga taaagatcca cgagccgtaa cgctgttttt cttcttgact
    33481 gatccaaact gctgtatctg ctaagattcc gattgtcagt gtagagataa tgacttcatc
    33541 attgacttga ccatagtcta ttttccgtac attgccttcc aggatcacgt cagcagcttc
    33601 ttcttttttg aggggaatct caagaacacg tgcaaggttg ttgacagttc cacctggaag
    33661 taatccgaca tggtattgag ataatgtttt ttggaacgct tggacgatat gatgaatcgt
    33721 gccgtctcca cctataatta ctaaagtatc agcttctatg gcttctgctt tcttgactaa
    33781 ttccgcatca tcaatcgatg ggccagtttc agctagttct acatataatt ctggctgctt
    33841 ttcttttaca taatcttgaa accagcgtgc taatttctca ccctcatctt tccctgaact
    33901 tttgttataa aaaactagca gcttttccat tctttacctc ctatttactc ttcaaaaaag
    33961 agggcgggac aaccaattcc attgtcctgc cctttagcct tagacagatg acattccatc
    34021 attgggacga acgccttgtc ataagctgtt ctttttcgat tttaactctt tgtgttcaat
    34081 tctgcaattt ttacaatcac gtctgttgct ttttccatta cttgtaaaga aacaaattcg
    34141 aatcgtccgt gcatattttc tcctccggca aatagatttg gcgtcggaat acccatgtaa
    34201 gagatttttg aaccatctgt tcctccacga actggttcga tcactggaga gataccaagc
    34261 tcgatcattg cttgtttcgc taattccacg atgctcatat ctttttcaat gatttctttc
    34321 atgttgtaat attgatcata catatctact ttgattcgtt cttgatcaaa tcgctgattc
    34381 aactcttctt ggatatgtgt gatttgtgct ttgcgtgctt cgaatttttc acgatcatga
    34441 tcgcgaatga tataactcat agaagcttct tcaggattcc catccaatgc catcaaatgg
    34501 aagaaacctt cgtatccttc cgttttttct ggaacttcat cggctggaag ctgattatga
    34561 aaatcgattg ctaactgtag agcattgatc attgtatctt ttgccgtccc tggatgtaca
    34621 tttttccctt ggatcgtaat atttgcttga gcagcactaa acgtttcata ctgcaactca
    34681 cctaaaggac caccatcgac tgtataagca aaatctacat cgaattgctc aacatcgaat
    34741 ttatccgctc cgacaccgat ttcttcatca ggaccaaaag ccactttgat ggtaccgtga
    34801 gggatagaag gattattgat caagatctcc attgcagtca tgatttccgc aatccctgat
    34861 ttgtcatctg ctcccagtaa tgtactgcca tctgttgtga tcaatgtgtg gccttcataa
    34921 tttttcaaat ttggaaaatc ttttgtattc aatgtatagc gttcttccgc atctagtacg
    34981 atcgtagact cgccatcata gttttcaatg atttgtggat tgactcctac tgcattaaaa
    35041 tctgctgtat ccatgtggga aataaatcca atggaacgca cttcatgatc aacattgctt
    35101 ggtaatgttc ccataacgaa tccgttatct tcattataga aaacatcagc taagcctaac
    35161 tcttctaatt cttttttcaa ttcttgcgca aaagcaactt gtgtctgagt cgatggagtc
    35221 gttttgcttg ttgcatcgga gcgtgtttct gttttgacat atcgtaaaaa acgtggcaaa
    35281 agattttcgt acatagtatt ctctcctttt aattaaattg aaatgggttt gtatttgttt
    35341 cagaaacgaa aaagttaata tcccaatttt cttcttgttt ccaagattca aatttctcga
    35401 taaatcgttg cttgcataac gattcaatat aatgaccggg atcaattgca atcaacccag
    35461 cgctttgcat atcatgagcc gtatgataat agatatctcc cgtgatatag acatctgctc
    35521 tttgggcgat tgcttgcgga taaaattttt caccgcttcc accgcaaatc gcaatgcgct
    35581 tcacagagga ttttgcattt tttggctgga ctattctcag tccatctagt tggaacgctt
    35641 cttttacttg ttctacaaat gcctctatag aaatttcttg cggcaattca cctactcgtc
    35701 ctaacccaaa catttcgact ggttcatcta tagcgaaaag atcataagca ggttcctcat
    35761 aaggatgagc tgaccgcatg gcttgaatca cttgtttttc gatagtttcc ggcaaaataa
    35821 cctcaacttt tgcctcttga acttgttctg tcttccctac tttcccaatc gctggttgtg
    35881 caccagcttc cggagtaaat cgaccgtgtc caatcgaggt aaaacttgta ccggtataat
    35941 caccttgtgt accagcacca gctgcagcta atacttcacg cattttctgt gcatgatcca
    36001 caggtacata aacggccagt tttttataat gaatctcatg agtctttact aaataactct
    36061 ccacttcaat accgagaagt tcacaaaacc agtcattcag tccatcccaa ataatatcca
    36121 tgttcgtgtg tgctgcatag acggcaatat catgtttcaa caaatctgca tacatttttt
    36181 cttgtggctg atcagtaacc agccgtttta caggacgaaa gattggagga tgtttagcaa
    36241 tcagcaaatc gatttttttc ttgattgctt cttcgaccac ttctggacga acgtctaatg
    36301 tcatcattac tcgttggatt ggcttatcca atgttccgat atgcagtccg actgggtctc
    36361 cttcttcagc tagccactga ggacaatagc tttcaaactt ttggatgaaa gtgcgtccgc
    36421 tgattgtcat ggctttaaaa cctcctcaat catttggatt tcctgctcga tttgtttttg
    36481 acgtgcctct tgattagctg cttgtttgag ctgttcacgg atagcttttc tttgttgaag
    36541 ctctcttgtc cattttgatt tgaagatctc acttttctct tcaagcagaa atggcccgaa
    36601 catcagctcc atttcattgt aagtaactgg tttttgttct ttttcggcta caatgatttc
    36661 atatattttt ttattttctt caagtatttt ttctgattgg attttatact gattttcttg
    36721 cagccaagat cgtaatgtac gctctccgat gtttggctga aggatcaaac gttcttgtcc
    36781 gcttaagcgt tgattcaact tgccagcttc taggatatct cggatcagtg aacctcccat
    36841 acccgcaatc gtgacagctg taataccatc ttgtggctgg atagcatcta gaccatttgc
    36901 aaggcgtacg gtgatacggt cttctaatcc atcttttttg acttgcttac gtgctgattc
    36961 ataaggacct tgaacgactt caccagcaac tgcatattcg atttttcctc ttaatatcaa
    37021 tgcaacgggt aagtaagcgt gatctgatcc aatgtctgct aaacgagcgg attcagggac
    37081 aaagtcaccc actgcggcta agcgctgaga taaatctaaa tggttcatag cttcactcct
    37141 tctagataat tatagcattt tccaaataaa ataaggagac taggaataaa aaaattccca
    37201 tatctcctta aaaaatatac cttttcgttc tataaaacaa cattttctta tttttgaaaa
    37261 aatgttattg gttatttgtt caatgaaaca tcaataatcg aatctccagg aacttgcggt
    37321 gggatagaca tcgtcatgat cggcatctca actaatgtaa attggacttt gtcaccgatt
    37381 ttcaattcat ttatgtccac gcttattttt tcagcagtag catttaagat cactccgtca
    37441 ttgctgaatg acgttcccat attcgctgga tcttctttgg ccatgacatc gacgagtttc
    37501 aactgaagcg tttcttcttc tgcttctact tgagtgatac tttcaatcgt tccgacaaat
    37561 atgctttgtc tctccgtttt cgtactgctt gtttttactg tttgacccgc atcaatcgaa
    37621 tcaacagaac ctgtgttgct atctgcgcta ccgcagcctg ctaaaagaaa aaatagacca
    37681 actacagata tactagaaaa aatagccctc ataaaaaatc ctccgtttaa gtttctgcat
    37741 tacttgttgc ggtgattgtc tccggtcatt tctgtccata taatgattcg ctgacctgct
    37801 tttactacta ggtcaaatgt cagttggact tgtcaactgt tcaaccattg cgtcggttgc
    37861 gaccagtcat ttcgatttct tttgtcaaat aacgtatgcg ttccattatc cgtttcgctt
    37921 ttagcggctc ttcatctcca cgttgagtga cggacaaatg ctgttccaat tcatccattg
    37981 taaaattcga tgagaagaag gttggtaact gttcctgcat ccgatattga aggataacac
    38041 cgaatacttc gtctcgtatc caactactca tcgcatctgc accaatgtca tcgatcatca
    38101 aaataggtga acgtttcact gcatctaact tttctgccac ttgatctttt ccgattgcct
    38161 gtttcatctc aacggcaaat gtcggaaaat ggactagcgt cgtggtgaat ccagcaatcg
    38221 ctaattctct cgctgttgct cctaataaat atgtttttcc aataccaaaa cttcctacta
    38281 gatacagtcc tttatgatac ccttttggat cagcagtata tttctctaca aaatctaggg
    38341 cttctaagct cgcatatcct cgtccatctg tacgttcaaa gttttcaaaa gaagccgatt
    38401 gaatatcttt tggcatatcc attgctttta ctcggcttct gatttcttct tgtctttgcc
    38461 gtgctaacaa tgcttccgtt ggtacataag tgacatccac ataatgaaaa ttcaacgtca
    38521 gcttcggctc atagccggga gcgatcatcg ttggatcgtt tttttgatat ttacgctttt
    38581 cttgcacgaa ttcatacaat ttagcgtaac ttttttcaat atccgcttgt gtcaattctt
    38641 cttggtgtgc gcttagaaaa gcttgaacat ccgcatcatt taagacttca gcgatcattt
    38701 cagcatactt ttcttgataa ttgcgtttgc tgatgatcct cttcaattct ttgcctacgt
    38761 cttccactag atatcaccct ccttttttgc caggtattct ttaaaacggc ggtcaatctc
    38821 tgcttttttc tcgctgctga tctgtttttc atcttttggc tggttgaccc aatcaggaag
    38881 cttttcccgt cgaacatttc gcttgccagt ttgataattt gtttgcttct tttgttttga
    38941 ttgttttgct tgattactta tttgccgaat gtgctggatc gcttcttctg ctgtggcgat
    39001 tttcttttgt gcccattcat ttgccactgt atttacataa ctggcattta agctagcatt
    39061 attcttgatc actagtacat aattcagcaa aacattgatc acgctactgg aaagacctga
    39121 ttgagaaaca agatcttgca gtaaccagtt ttcttgttta gaaacatatc cgcctttttc
    39181 tgacttgatt gcttccagat atttcatcgg tggaatgctc tgtgcttctt ttatcagctg
    39241 aagcgctgcg tttgtcaaat gttcgtttga cgagggttca ttactgtttt cagaaaccgc
    39301 aactgtttct tttgtttgct tcaccggacg tctctgcatt gccaaaatgg ctttttgcag
    39361 ttctttttca gatacttttt gttcactaaa gtcataagat tgactgatca gttcgccaag
    39421 tgtcaattca tcgaaaccgt aaagctgatg atacatgtcg acttgtttga tgattggatc
    39481 atcaagactt gcaatatgtt tttttgccag ccaatcattc aaaaactgcc aatcgaatgt
    39541 cgaatctgct tcaagtaatg ctactgattc agattcttca aaagatttat tcagcgattc
    39601 gatgttttct tgattagcag cgtacactgc ttcattgaag cgataaacat ctaaaaattt
    39661 ttttgtgatt ttttgatatc cctctgctgt atgcctttta ggttcaaaga attgggtaag
    39721 cttctggaat cgtcgttcac caactttttc cagaagaaga aaagccagaa cagagtcttt
    39781 gaaaaatgct ttaggaatga gtggttctaa cagctcataa ataaaacgag gtcccagatc
    39841 actatcttct ttaaaataaa catccagtaa gccgattcct tctagctttt ttcttgcatc
    39901 ataaaattgc gggataccgc agcctagact actaagcaga tctgcatgca tcccttcagg
    39961 acctttgcca gattcttgag agatttctga taacagggtg aaatagatac tcaaggcttc
    40021 tccgccgatt agtggctgat aaagatacag caaggcgttc ttgctgtctt ctctcagcgg
    40081 agccgctttt cttccttggt aaatattttt tggttgaagc tctttccaag cattttccaa
    40141 ggaaatgcct cctttttgtt tcttaattgt tttctttatt attctcttta ttattttctt
    40201 ttgctttatc cacgatatct tgcaactctt ttaagaaaac agacatatct ttgaactggc
    40261 gataaacact tgcaaaacga atataagcga tttcgtctaa atcaactaaa tcttccatca
    40321 catattcacc aattagattc gtcgatactt cgttttctcc gagactgcgt acgcggtttt
    40381 cgacatggtt gacgatttgt tccatttgtt ccatagctac aggtcttttt tctgctgaac
    40441 ggatgagtcc tcttaaaatt ttatcgcgat tgaactcttc gcgttccccg tttttcttga
    40501 ttactaataa cggagcagct tcaattcgtt caaatgtagt gaatcggaac gaacaattct
    40561 cacattcgcg acggcgacgg atcgcacgtc catcatctgc ttgacggctg tcgattactc
    40621 gtgaattatt atgttgacat ctgggacatc tcattttgtc tcacctcttg catcgcattt
    40681 tatataaagg atgtgtcttt ctttacaact agttgtatta taacacgaaa caaatcacaa
    40741 acgcgactgt cctacccaaa aaacacggat ataagaacaa ttttttctac tttcatgcgt
    40801 aattgtgtcc cctgtcctta ctaaatttca attttccaat actgatcacc ttgattactg
    40861 agaaataact tacacaaaag ctgatttagt catctagcac aaaaaacttg aagcagatga
    40921 acaccttctc atctgcttca agtcacatct cgatttttta ctattttata acttctcttc
    40981 gattcctgta tagtgtttca ttcgctgttc ctcgattttt tgctcatcgg gaatgtggtc
    41041 actttctggg agcggtgttt tactacgatc aggtgtcgga ttttttcgtt cttgagtcaa
    41101 atcttgccgc ttcgcttctt cttctgcctg ctggtcttct atttcatcga ttcttgcttg
    41161 gtactgcttt tctttttctt ctgctgtttc tgattgcgta cgaccttcat cgattagatt
    41221 ttctttattg agcatctcgc cgattttttc ttttgcgtta cctacgactt tatccttttg
    41281 attttttaat gatcccatcg ctatccctca ctttctatat actcaggata gcaaaattga
    41341 cacagatact caaagaaagc gattagcaaa aagccaattt tcgatttgtc ccacaagtat
    41401 ttcttttgtt ccattgttgt cgaacaaaat atccgcacgc tgcttttttt cttcgattgg
    41461 aagttgacta ctaattctct gctgcgcttg ttctagcgtc agttgattac gtttcatcaa
    41521 acgctgaagc tgagtttctg gcgtagtata aacgacagct actgcatcca tatagtggtc
    41581 ataatgacct tcgtagagca atgggatatc tacaattact aaaggatgat tggaacttag
    41641 agaggcgatt tgatctttta tcgcttttcg gataaacgga tctaatagct gatcaagttt
    41701 ttgccgtttt tcctttgatg gaaaaacaat catcccaagt ttccctcgat ctagttgccc
    41761 atcaggctgc aatacctctt ggccaaacac tgatacaatt ttcctcagag caagcgttcc
    41821 aggctcaaca gtttctctgg caatcacatc gccatcgatc aaaggaaatc catgagactg
    41881 aaagactttg gctgccgtac ttttaccggt agctattcca cccgtcaaac ctaaaacaaa
    41941 tcctactttg cgatttttag cctttgacaa ttcggacaat agtgcgtccc cctttgtgcc
    42001 acttttgttt tcacgatcgg cgttccacaa cgtatacatg gtttgccagt ttgctgatag
    42061 acatgcagtg ctacttgaaa tccgcctgat tctcctaatg cattcaaata actgcgaatc
    42121 gtggtacctc cggcttctat tgcacgatcc aaaacatcaa tgatcgatag acgtaattgt
    42181 tctacctctt tggggcgcag tgtgttcgcc ggttgttctg gatggatctt cgcttcccat
    42241 aatgcttcat ctacataaat attacctaga ccagtcacta gacgttggtc tagcagcaat
    42301 ggcttgattg ctttgtggga ctttttcagt ccatttgcga aatctgctaa taagaagcta
    42361 tctggcaaag gctcaggtcc caatttcatg attcctcggt aagttgcact tgctcctttt
    42421 tcgacgattg tcatacgacc aaattttcgt acatcgttgt agcgaagttg gcttccatcc
    42481 tcaaaaaaga aaagtacatg cgtatgttta tcgattggtg tattttcttt cgtaaattga
    42541 tattttcctt ccattcgcaa gtgtgagatc agttcacaat gatcgagatg aaaaattaaa
    42601 aacttccctc tacgtccaat ggattggatg gtttcgccaa caagagaagc ctcaaagatg
    42661 ggtgtctctg gttgctcgat gatcttgggc cacaagacct gaactttttg aatcgttttt
    42721 cctactacta accgttccaa tcctttacga acggtttcta cttctggtaa ttctggcatt
    42781 ttttcttttc accttcatta tattgctctg tcttaaacaa tgtttatttt gcttcgtacc
    42841 acgtttttcc ccaactgctg tcagtgatca gtggtacatg aagagaaaca gcttgttcca
    42901 taacttcctt caccaattta tctaatgatt caagttcttt ttccggtacc tcgaagacaa
    42961 gttcatcatg aacttgtaac agcatcgtag cttgaagacc tgtttctttt aatcgtttat
    43021 ccaattcgat catcgcgatt ttcaaaatat cagcagcact tccttggatt ggtgtattga
    43081 tagctgttcg ttccgcaaaa gaacggatat tgtaatttct tgaattgatg tctggcagat
    43141 atcgacggcg gtgatacagc gtttcgacgt agccttggtc ttttgcttcg cgtacgattc
    43201 tttccatata ttctttgaca cctgggtatt tttcaaagta cgtatcgatg tattgctgtg
    43261 ctgcttttcg gctgattcct agattttgtg aaagtccgta atcagagatg ccatacacga
    43321 taccaaaatt cactgctttt gcctgcctac gcatatttgg tgtgacatcc tctgcctttt
    43381 cgattccaaa tacacgcatc gctgtgctgg catggatatc ttgaccttct aggaaggcag
    43441 ctttcaaatg ttcatcattt gagatatgcg caagtacgcg taactcgatt tgtgaatagt
    43501 cagaagaata aatcagccag tctttttctc taggaacaaa tgcctgacgt atctttctcc
    43561 cttcatctaa tcgaatcggg atgttctgca aattaggatc aacagagctt aatcgtcctg
    43621 tttgggtcaa tgtctggaca taacgggtat gcacttttcc atctgattgg atcactttca
    43681 gcagtccctc gacataggta gattgaattt ttgcaatttg acgataggtg aggatatcct
    43741 ctacgattgg tgcttgttca cgaagctgtt ccagtacatc tacggctgtg gaatatccag
    43801 tttttgtttt tttgataacg ggtaatccca ttttttcaaa taagatcact cctaattgct
    43861 ttggtgaatt caaattgaat tcttcgccgg cttcttcgta gattttttgt tcgatctctc
    43921 ttaagcgagc agagaactcg cccttcattt cttgtaagcg agtcgcatct actttgatcc
    43981 cgcttatttc catctctgcc aaaatgatag acaatggcag ttccattttc cggaaaagat
    44041 cttcttggtt tttttctgcc agttcttggc tcaattttgg tgtcaacgca ttgattgcag
    44101 ctacttttcg cgctaaatga gcaaaaaaga gttcctcttc ttctggtaaa ccttttttcg
    44161 cccctttgcc gtatacagct tcatctgatt ggatatcgtt gtatccgtaa tgagcagcta
    44221 ttccttcgat atctgtgctt ttttcattcg tatcgagaag gtatgcacct agcaagacat
    44281 caaaatcgat tcctttcgtt tttccagtat agcggtttaa agcaacataa gttcgtttcg
    44341 catcatatac ttttttcagc cgagtcggat cagtgatcca agaatggaac gctcggtttt
    44401 cgaatacaga tagatcgttc gtgacataaa ttttcttttc tgtcccccac gctactccga
    44461 cgatttcctc tgtatgataa ttgtcgccca tcatttccac gtacaacgcc atatccgtag
    44521 taaacatttc ctctttgaat tcatgaacga cttcaaacaa aatatcatcc atttttactt
    44581 cttcttctac gatattcaat ttagaaagga actgattgaa atccatttct ttataaaacg
    44641 gaacgagttt atcgagattt ttcccttcat acttcaatga gtcgatagag acatccacag
    44701 gcgctgaagt attgatggtc gccaattttt tcgataagaa agcctgctct ttgtcattta
    44761 tcagattttc tttcattttg ctttgcttca tttcatcgat atgttcataa attccttcga
    44821 ctgagccata ttgtttcaat agcttgatag ctgttttttc accgatttta gtcacaccgg
    44881 ggatattgtc agaggcatct ccggctagtc ccttcatgtc aataatctgt tttggcgtca
    44941 acccatcata tttttccgct acatgttctg gtgtatagct ttcgatatcg ctgacacctt
    45001 ttacagtgat atccactttt acttctttac tagctaattg agtcaaatcc cgatcacctg
    45061 aaagcacgac gacatcaaat tgatctttgt ctactttttc tgccaaagta ccgataatat
    45121 catctgcttc ataattgggc aattcgtaat actgtacccc tagtcctgtc aacaaatcac
    45181 gtatatatgg catttgttct ttgaattcgc caggtgtttt ggatcttcca cctttgtact
    45241 ccgcatacat ttctgtccga aaagtcgttt ttcctgcatc gaacgcaacc agaacatgag
    45301 tcggttgctc tttttgcata acattttcaa acatcgtatt gaatgcatag attgcatttg
    45361 tatgaagacc gtttctattt ttgaaacgtt caagagaatt gtgaagcgca aagaatgcgc
    45421 gaaaagccac actgttccca tcaacgagta ataatttatt ttttgtcatc ttcttaactc
    45481 cttactgtaa agttcttatt cattctaaca aagaatcctg cggaatgcga aaagaaaaag
    45541 cgggaccata ccaaataatt cggtatagcc ccaactgatg aatttttttc ttttttagtt
    45601 gttccgtcca aagattctca gaaacgccaa gaacaagttg ataaagtcca aatacagctt
    45661 caatgccatg aatacagcaa ttccactatg tgctgttccg tttgtctgga catagatatt
    45721 acggatgctt tggttatcat aagctgtaat ccctgcaaag atgacgacta acagtaggga
    45781 gatgaacagc tcaactacgc tacttctcaa aatgaagatg ttcaagacta gtgcaatgat
    45841 cactccgatt aaagctgcct gtcctgctct tccaaccccg ctaagatctc tttttgttgt
    45901 tactccgaca acagacatcc ccatgaacat caaagtagct gtcaagaaag cttgcgttac
    45961 tgttccaata tcgtagtatg caagagtaac cgctaatatt atgccattca aaagagagta
    46021 ggcaataaat ccaccgattg ctaagctcgg attcttttgt gcttttacgc ctagaaccat
    46081 tactaaaatc agttcaacga tccacagacc cacaaagcct agtggaaaat tattgataaa
    46141 agttgctaat tgcaaaggaa atacccaaag agccaagtaa gaagtgactg cactaagggc
    46201 aagtcccata cctaaaaatc cataaacttt tgcataaaaa cgattgatac ctgacattga
    46261 tgtacttgga ttattcattc aattcacctt cactttcgat tgctatttcc aattcaggaa
    46321 cttgtggcgg ttggaccata acgacagcat ccaacacacg atcttcgttc gtattctccg
    46381 cttctacaga aatcgtcacc acatccttca tcttatctac ttttatgacc tcaaactgaa
    46441 aagtcagtgt ttcataatgg aaaaccggtt caataaaatt gacagaaaaa ttgacaacat
    46501 gtgatcctgg tccaggaaga tgctttgaaa ttgcacttgt gatgatcccc atcagcatca
    46561 ctgatggaac gattggctgt tgatattctg ttttttgtgc aaagtcatgt tggatataca
    46621 aaggatttgc atcattcgtc aatcccaaat acagcaaaag ctggttatct tcaatagatt
    46681 ctgttaagga taacgagtcg ccttcctcga tttcatttat tgtttttcct agttttctcg
    46741 gcttacctat gttcaagata gaaaccctcc agtttatttt taatcataca ttattgtacc
    46801 aaaagtagcg taaaaggcaa gttctgctcc cttgatttaa cagattccta tagtttacag
    46861 aggtcgtgaa aaagctgtcc tgcatcaaat aataagaaca gccaagaaaa aacagcttct
    46921 catgtttttg atttgattgg gcttattacc gcagatgcaa gcttttgaac accgtttatc
    46981 ataagttgca aaaaaggggg cttggcaaga tttttgccac tccccctctt tctattttta
    47041 taaggacact gcagtaattg tattacagta catttttcgt cgtgctgctt aaaagttttt
    47101 catacgcttg ttcaaatttt tgaacatctc cagcacccat gaagattact actgcatcat
    47161 gataatctaa caatggagat acattatttt ctttgatgac ttctccacct tttttgattt
    47221 tcgctccaag gtcttcaatc ttaacgtttc cttgttcttc ccgagccgaa ccaaaaatat
    47281 cgcataagta aactttatca gctaaatcaa gtgcttctgc aaattcatcc atcaatgcaa
    47341 tcgtacgcgt aaacgtatgg ggttggaaaa ctgcaattat ttctttatct ggatattttt
    47401 ggcgtgcgcc atcaatcgtt gctttgatct ctgcagggtg atgcgcataa tcatcgacta
    47461 cggtcatgtc tgctacgatc ttttcactga atcgacgttt tactcctggg aaagtcagca
    47521 tttcttctgc aacttctttc agatccagtt tttcgaaata agctactgca ataacaccta
    47581 aagcatttaa gatattgtgt ttaccgaatg ctggtacagt gaagtgccca acaaattcat
    47641 ccccatgata gacatcaaaa gcagaaccag aagttgtgcg ttcgatgttt cgtgcttgga
    47701 tatcatcgtt ttctgtgaca ccataataat aaatcggcac atttgctttt aatttgcgta
    47761 aataagcatc gtcaccatac gcaaaaatag cttttttcac ttgtccagcc attgtttgga
    47821 aagctgtaaa tacatcgtcg atacttgtat aataatccgg atgatcaaaa tcgatattgg
    47881 tcatgattgc atagtctggt gaataggcaa ggaaatgacg gcgatattca caggcctcaa
    47941 atgaaaagaa ttccgcttgc ggatcaccat gtcctgttcc atctccaatt agataacttg
    48001 ttggacggac accactcaat acatgagaga gcagtccagt cgtacttgtt tttccgtgag
    48061 agcctgttac agcgatactc gtataatttt ggataaaatg accaataaag tcgtgatagc
    48121 gaatcacttc caaacctaat tcttttgctc gctggatttc ttcatgtgaa tcaggaaatg
    48181 catttcctgc aatgatcgtc atccctggtt ttacattatc tgcgttaaat ggcagaatcg
    48241 tgatatttgc tttttctaaa tctctttgtg taaagaaata tttttcaatg tctgatcctt
    48301 ggacatttag accttgttca tgtaaaacaa gagccaagga gctcattcct gaacctttga
    48361 taccaacaaa atgatacaat ttattttgat tttccatttg aatcctcttc tcttatctag
    48421 cgtccattct tttagctatt acattcaaca cgctcctcat tatcttataa acgattgaaa
    48481 atttcaacca aatttatttg gaaaggagga ttcgcttgct aaaatggtca agtacgagaa
    48541 aaatccgttt ttattgactc tttaattctg gtgtaagaag accaaacttc ctctgatata
    48601 tcaatgtgag gaataaaatc ttttcctttc ggaccatagc cgttctcatc gtcatggaga
    48661 cgttccattt ctcctaatac tagcgcatgg aaatattcct taggccattg atgattcagt
    48721 tcttttgctg taaagatgat ctcttcagaa aagtgaagga tttccggcac aaatggcaca
    48781 gcattcgcga aaatagtttg ttcattttgc catactttct caaaagttgc tcgagtcctg
    48841 cgttgcagtg tcggatcatt catcaataag attttttctg gtacagctcc taaggaatga
    48901 agaatctcca gtgaaaaagt ggcgttctct ccagaatttg tagacttcga ttctatcaga
    48961 aaagccttat cgggcaaatc atagacttct tttagatact gacgacagat ttcactttca
    49021 ctcatgccat cttcaaaatg aaatccttgc ttttcaaaat tctcataaag gattctagtc
    49081 gcatgcccca cccctccgac caaaaacaat tgatctactt ggccatttaa atacatttgt
    49141 gctgctttat cagctaagat aggaagacag tttccagcta aaataagtgt aggtgccgtc
    49201 agttcctcaa aatttccctc ttcaggtgcg gctaaaaaat ttaatagctg attccagtct
    49261 tttagattcc tctgctcact tttttccaaa ggccttctat cctttcatct gattttttgt
    49321 gcttcattaa agtcttctct ttttgtctca atccatttga tttctccatg acatcttcca
    49381 caacgatatt tgcgtacatc gattcttctc ttgcggcaga tcgtggcaga acaatcttgg
    49441 catcgataat actccatctt tatctgtttc ttcgtcaagg ctggtgcata gcgcaaccct
    49501 cctgtttttt tcaaaagata cttgaaatcc atatctttat gctgataccc tcttccagct
    49561 agatgaagat gataatggca aagttcatgt ttgatgattc ctgcaatcgt ctcttcgtct
    49621 gactcttcaa atagcttcgc attaaaatct aaatgatgat cgtttaaatg atagcgcccg
    49681 ccagttgtac gtaagcgtgg attgaacatt gcttggtgct tgaaaggaag ctggaagctt
    49741 tttaatgata tctcttctac taactgctgc agttcttctt gtgtcaattt ttgttactcc
    49801 tcattgttac tcttcataag gggaaagcat cgtcaaactg attctgcctt ttttcgtatc
    49861 gacttgttct atccaaactg ttacgatatc tcctactgac acgacatctg taggatgctt
    49921 gacgaatttt ttgctgagtt tcgatatatg gacaagtccg tcttgcttca caccgatatc
    49981 aacaaatgcg ccgaagtcaa tgacattacg gaccgttcca gtcaattcca tccctggttt
    50041 caagtcttcc atactcaata catctgtacg taataagggc gctggcatct catcacgcat
    50101 atctcgtcca ggttgtgtca gcccagctaa aatatcggct aacgtttctt ctccgactga
    50161 taggctttca gccagtttct ctacggataa tcgtgtcaat ttttctactg cttcttctgt
    50221 accaagctct ttttctgaaa gttggactga agttaatatt tcttttgcaa tagaataact
    50281 ttcgggatgg atacctgtgt tgtccaaaat gtttttccca ccagggactc gcaagaatcc
    50341 gattgcttgt tcatatgctt ttggtcctaa gcgtggcact tttttcaatt gagttcgtgc
    50401 ggtgaattct ccgttttctt cacgataaat gacaatgttt tgggcagttg ttttattcaa
    50461 tcctgatata tgctgcaaga gctgcgggct tgctgtattc acatccacac ctacttggtt
    50521 aaccgctgtt tccacaacaa aatccaattg ttcagccaaa cgtttttgag aaacgtcatg
    50581 ttggtactgg cctactccga cagctttagg atcgattttg actaattcag ctaaaggatc
    50641 ttgcaggcga cgggcaatag aaacagcact tctttcttca acttgtagat gcggaaattc
    50701 ttttcgtgca atttcgctag cggagtaaac agaagcgcct gcttcgttga cgatagcgta
    50761 ataggtttta tggtcggcgg atttcaactg ctcagccaca aaaagttcag attcccgact
    50821 ggctgtacca tttccgatag ctaccatatc tacttgatat ttattaatta attggataaa
    50881 agctggtcca gcagcttctc tttttgcttg cgctgcaggt ttatgaggat aaataacttc
    50941 gattgctaaa actttccctg tcgcatctac gactgctagt ttacatccag tacgataagc
    51001 cggatcaaat cccaggacaa ctttaccttt tagtggcggt tgcaacaaaa gattacggag
    51061 gttttcgccg aaaatagcga ttgcttgctc atctgccttt tcagtcaatt cattgcgcag
    51121 ttctcgctcg attgctggct gaataaagcg tttataacta tcctgatagg cttctctgac
    51181 gaatgaagaa gaaggagagg caggattttt gactatttgg cgatccaagt aagctaaaat
    51241 tgctgcttca tctacttgaa agaatacttt cagaatatct tctttttctc cacgattagt
    51301 agctaatatt cgatgagaaa ccattttatg gacgggttct gcaaagtcat aatacatttc
    51361 atatacgcct ttttcatctg cttgctcatc cttgacattg ctgacataca tacctttgtt
    51421 atacgtataa gaccgaatcc aagtccgaaa ttttgcatta tcgctgactt gttcagcaat
    51481 aatctcatga gcaccgtgca acgcttcttc ggcagaagag acttcttttt ctttgtcaat
    51541 atatttttct gcttcagatt gcacctctcc atctgtaagc tgcatcagcc acttcgcgag
    51601 tggttcaagt cctttttctt tagcaatcgt tgcttttgtc cgtcgttttt gtttgtatgg
    51661 acgatacaaa tcttccactt gttgcatttt cacggcttgg gtgatttctg cttctaactc
    51721 gggagtcagt ttcccttgtt catcgattag ccgaatcact tcagttttac gtttttctaa
    51781 gttttcaaga taggcatacc gctcttcgat ttcacgaatc tggacttcat caagacttcc
    51841 agtcatttct tttcggtaac gcgcgataaa aggaacagtg tttccttcat ttaacaaatt
    51901 aagtacagta gtcaactgct taggacgata gtctgaaagt tctttttgta caagctgaat
    51961 gatcgtctgg ttcaaatttt ccgtcattaa aatgcctctt ttctgctaaa aattgcttct
    52021 ttattctatc atacttttta tcctgggtta aactactgaa agaaacaata ttctctataa
    52081 aaataaaaag agccgcaaca aagtcacagc tccttcattc tttccattag tcagattcca
    52141 tgccaaggtc cttcgttgtt ctgatattca atatcttgaa gaataccttc cttgtcaaaa
    52201 acaaccccat gcaatgaccc tccgaataca gccccaccgt ccattccgat tttatgatcc
    52261 tgaatccaga ggtctgttgt ctgcatatct ccatggagca ttggtgtaat cgtatgtcca
    52321 aatacaattg tcttacctgt attgtttttc ccttcatgaa atggttccct tatccaaata
    52381 aagtctctta gacttgtctt acgccagtct ttctttgtca aatccacacc ggcatggaca
    52441 aaaagataat tttcccattc ataatacaag gggcgctgga ctaaaaattt aatcagttct
    52501 gaatatctcg attggatcat catcgagatt tcagttgggg agtattcctc cgatgcccct
    52561 gggtgaatca ggctttcaaa cgtttctttt ccaccatttc tcatataagg cgcataccag
    52621 tcctccggtg attgcagaaa ttgcaaaaaa tattcttcat ggtttccccg gaggtaaatg
    52681 gctcctgttt cttcgactaa ttgctttcct aataaaaaac attcttttgt acgaggacct
    52741 cgatcattga gatcccctaa taaaacaagc tgatggatct ttggatcata atagtgaata
    52801 agtttttcaa aaagctcatg tttgccatgg acatccccaa tagcataaat caatgatttc
    52861 atgtggatca ccatcctcaa cgctagtata gcgcatattg gaaatggtcg acaatcaaaa
    52921 ctattgtttt ctatttaatt aaagctgtaa accgcagttc tgcttcttct ggagagattc
    52981 catggtcttg aacatagcga ttgcgcggat gtttcgcaca ctctatgcta catgctccta
    53041 aatgtttttc ttcattttca atggaagcaa gaatctgacg attgcactca ggattgctac
    53101 aattgatata tcgttcacat ggtgttccgt caaaccagtc gcgaccgacg atttgtttat
    53161 ctacttggtt gatatcgaca gcgatccgtt catcaaacac atacatcttg ccgtcccata
    53221 attctccttg gacttcagga tccttaccat aagtagcaat accgccatgc agctgtccga
    53281 catctttgaa tccttcacgg acaagccaac cagaaaactt ctcgcaacga atgccaccag
    53341 tacagtaggt cactacccgt ttttccataa attcttcttt gtgctcgcgg atccagtctg
    53401 gaagctctcg aaaactgcgt atatctgggc gtacagcccc tcgaaaatgt cccaagtcat
    53461 attcataatc attccgtgca tcaatcacca ctgtctgttc atctaaaata gcttctttaa
    53521 attcttgcgg tgaaagatag gcacctgtca cttggtttgg atcaatgtcc tcttctagct
    53581 ttaaacttac aagctctgga cggtatctta caaacatctt cttaaaggca tgtccttcgc
    53641 ttggatcgat cttgaacatc gtatcagcaa atcgaggatc agctttcatt gctttcatat
    53701 aggcagtcgt gttttcaacg gttccagaca cagtaccatt tattccttct tcagctacta
    53761 gaatacgacc tttaagatcc aaagatttgc aaaaggctaa atgatttttg gcaaattcct
    53821 ctggttcttc gatttttgta taattgtaat aaagcagtac ttgataatcc atgtatttct
    53881 tccttccttc ttttcgttcc taaacagtat aaagaaggcg ttcgcatttg acgatttatt
    53941 tgcttgtgta taattacgca tggaaagttt tttgtttaca taatattatt atttgaatta
    54001 aaaagacttc gctttcctgt ttcgcacaga aaaacaaagt ctttatttct attatttacc
    54061 tgtaaccgca aagtagttgc catcgggatc agcaaagtta aagacatatt cttctccaag
    54121 ctgtaccata tcacctaatg tgactgattg cgtctgcatt tttttatata gtccaaagat
    54181 atctttactg taaaacatca aagatggggc actagtagct gtgccaggtg aatgggactc
    54241 aacaaatgct cgatcatata acagaaatga ggtttgactg tcctcaactc ctacttcaat
    54301 tataagcgtc ccatccattt cttgacgatc tttttccgca aagccaactg ctctccaaaa
    54361 cgttgcattt ttttctacat cgtccacata aagcatgatt tttatttcat tcgtaaacat
    54421 ct
//
LOCUS       DADGHT010000005        52664 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.005, whole genome shotgun sequence.
ACCESSION   DADGHT010000005 DADGHT010000000
VERSION     DADGHT010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.005"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            72..656
                     /locus_tag="JX887_000250"
     CDS             72..656
                     /locus_tag="JX887_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HAX1256267.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDIPVGTDVEVYGPDDKKSETYANENTMGSVAPGKQM
                     DVTAHFTLNQKGEIEIHFSPLVSFEKAAIFKATV"
     gene            758..1906
                     /locus_tag="JX887_000251"
     CDS             758..1906
                     /locus_tag="JX887_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1256268.1"
                     /translation="MLKVWVEQTKDGQFKFIERYVDPYTEKTRKKSTTLTSNSPQAWK
                     KAQKILDKKIKEALENYNKSDITFGELYKEWYEYYKQHVKRTSYLKVPMMMKHVSKHI
                     SDDTIVRNIDETLINKMIEDMYTFGDLSLNYTKQTKTTLSVMLNYAIDRKYIQRNPAL
                     AVKIHPKKVEEEKRKLSMDKKYLEKEEIDQILKQLYSNPRRKLHGIIAEFLYLTGLRY
                     GELLALQMKDYGEGKISINGTLDYTSVKMDNAIKTTPKNTYSQREVQLSNRAKELIES
                     VIADNILAGRPTNPDQYIFISTNGTPLTLHSFNAVLHKVEEELELEKNLSSHIFRHSH
                     VSLLSELGVPLKAIMERVGHSDANTTLSIYNHVTKKAKQQVIDKLNRL"
     gene            complement(1995..3620)
                     /gene="groL"
                     /locus_tag="JX887_000252"
     CDS             complement(1995..3620)
                     /gene="groL"
                     /locus_tag="JX887_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAX1256269.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(3671..3955)
                     /locus_tag="JX887_000253"
     CDS             complement(3671..3955)
                     /locus_tag="JX887_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAX1256270.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            4180..4842
                     /locus_tag="JX887_000254"
     CDS             4180..4842
                     /locus_tag="JX887_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAX1256271.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(4918..6210)
                     /locus_tag="JX887_000255"
     CDS             complement(4918..6210)
                     /locus_tag="JX887_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1256272.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            6380..7009
                     /locus_tag="JX887_000256"
     CDS             6380..7009
                     /locus_tag="JX887_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HAX1256273.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(7112..7921)
                     /locus_tag="JX887_000257"
     CDS             complement(7112..7921)
                     /locus_tag="JX887_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAX1256274.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7976..8845)
                     /locus_tag="JX887_000258"
     CDS             complement(7976..8845)
                     /locus_tag="JX887_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256275.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(8846..10162)
                     /locus_tag="JX887_000259"
     CDS             complement(8846..10162)
                     /locus_tag="JX887_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256276.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(10159..11994)
                     /gene="walK"
                     /locus_tag="JX887_000260"
     CDS             complement(10159..11994)
                     /gene="walK"
                     /locus_tag="JX887_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAX1256277.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(11999..12703)
                     /locus_tag="JX887_000261"
     CDS             complement(11999..12703)
                     /locus_tag="JX887_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1256278.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(12893..13753)
                     /locus_tag="JX887_000262"
     CDS             complement(12893..13753)
                     /locus_tag="JX887_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAX1256279.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(13740..14309)
                     /locus_tag="JX887_000263"
     CDS             complement(13740..14309)
                     /locus_tag="JX887_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAX1256280.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            14690..14762
                     /locus_tag="JX887_000264"
     tRNA            14690..14762
                     /locus_tag="JX887_000264"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14723..14725,aa:Lys,seq:ctt)
     gene            complement(15258..15644)
                     /locus_tag="JX887_000265"
     CDS             complement(15258..15644)
                     /locus_tag="JX887_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAX1256281.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(15641..16162)
                     /locus_tag="JX887_000266"
     CDS             complement(15641..16162)
                     /locus_tag="JX887_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAX1256282.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(16164..17198)
                     /gene="sppA"
                     /locus_tag="JX887_000267"
     CDS             complement(16164..17198)
                     /gene="sppA"
                     /locus_tag="JX887_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAX1256283.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(17231..18646)
                     /locus_tag="JX887_000268"
     CDS             complement(17231..18646)
                     /locus_tag="JX887_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HAX1256284.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(18615..20768)
                     /locus_tag="JX887_000269"
     CDS             complement(18615..20768)
                     /locus_tag="JX887_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HAX1256285.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            21026..21262
                     /locus_tag="JX887_000270"
     CDS             21026..21262
                     /locus_tag="JX887_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAX1256286.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            21281..21496
                     /locus_tag="JX887_000271"
     CDS             21281..21496
                     /locus_tag="JX887_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAX1256287.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(22199..22951)
                     /locus_tag="JX887_000272"
     CDS             complement(22199..22951)
                     /locus_tag="JX887_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1256288.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(22966..24213)
                     /locus_tag="JX887_000273"
     CDS             complement(22966..24213)
                     /locus_tag="JX887_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAX1256289.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(24289..24435)
                     /locus_tag="JX887_000274"
     CDS             complement(24289..24435)
                     /locus_tag="JX887_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HAX1256290.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(24539..24850)
                     /locus_tag="JX887_000275"
     CDS             complement(24539..24850)
                     /locus_tag="JX887_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAX1256291.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(24852..25049)
                     /locus_tag="JX887_000276"
     CDS             complement(24852..25049)
                     /locus_tag="JX887_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAX1256292.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(25443..27170)
                     /locus_tag="JX887_000277"
     CDS             complement(25443..27170)
                     /locus_tag="JX887_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1256293.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(27163..28356)
                     /locus_tag="JX887_000278"
     CDS             complement(27163..28356)
                     /locus_tag="JX887_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAX1256294.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(28543..29187)
                     /locus_tag="JX887_000279"
     CDS             complement(28543..29187)
                     /locus_tag="JX887_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1256295.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(29281..29415)
                     /locus_tag="JX887_000280"
     CDS             complement(29281..29415)
                     /locus_tag="JX887_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAX1256296.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(29417..31549)
                     /gene="feoB"
                     /locus_tag="JX887_000281"
     CDS             complement(29417..31549)
                     /gene="feoB"
                     /locus_tag="JX887_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAX1256297.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(31546..32019)
                     /locus_tag="JX887_000282"
     CDS             complement(31546..32019)
                     /locus_tag="JX887_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAX1256298.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            32420..32644
                     /gene="nrdH"
                     /locus_tag="JX887_000283"
     CDS             32420..32644
                     /gene="nrdH"
                     /locus_tag="JX887_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAX1256299.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            32803..34962
                     /gene="nrdE"
                     /locus_tag="JX887_000284"
     CDS             32803..34962
                     /gene="nrdE"
                     /locus_tag="JX887_000284"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAX1256300.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            35012..35977
                     /gene="nrdF"
                     /locus_tag="JX887_000285"
     CDS             35012..35977
                     /gene="nrdF"
                     /locus_tag="JX887_000285"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAX1256301.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(36066..37205)
                     /locus_tag="JX887_000286"
     CDS             complement(36066..37205)
                     /locus_tag="JX887_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAX1256302.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(37514..38227)
                     /locus_tag="JX887_000287"
     CDS             complement(37514..38227)
                     /locus_tag="JX887_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAX1256303.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(38481..39182)
                     /gene="nagB"
                     /locus_tag="JX887_000288"
     CDS             complement(38481..39182)
                     /gene="nagB"
                     /locus_tag="JX887_000288"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAX1256304.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            39416..40948
                     /locus_tag="JX887_000289"
     CDS             39416..40948
                     /locus_tag="JX887_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAX1256305.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(41139..42341)
                     /locus_tag="JX887_000290"
     CDS             complement(41139..42341)
                     /locus_tag="JX887_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1256306.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(42423..43112)
                     /locus_tag="JX887_000291"
     CDS             complement(42423..43112)
                     /locus_tag="JX887_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAX1256307.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(43218..43586)
                     /gene="rplL"
                     /locus_tag="JX887_000292"
     CDS             complement(43218..43586)
                     /gene="rplL"
                     /locus_tag="JX887_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAX1256308.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(43639..44142)
                     /locus_tag="JX887_000293"
     CDS             complement(43639..44142)
                     /locus_tag="JX887_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAX1256309.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(44552..45241)
                     /gene="rplA"
                     /locus_tag="JX887_000294"
     CDS             complement(44552..45241)
                     /gene="rplA"
                     /locus_tag="JX887_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAX1256310.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(45345..45767)
                     /gene="rplK"
                     /locus_tag="JX887_000295"
     CDS             complement(45345..45767)
                     /gene="rplK"
                     /locus_tag="JX887_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAX1256311.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            46110..46778
                     /gene="sdaAB"
                     /locus_tag="JX887_000296"
     CDS             46110..46778
                     /gene="sdaAB"
                     /locus_tag="JX887_000296"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAX1256312.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            46791..47663
                     /gene="sdaAA"
                     /locus_tag="JX887_000297"
     CDS             46791..47663
                     /gene="sdaAA"
                     /locus_tag="JX887_000297"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAX1256313.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(47754..48773)
                     /locus_tag="JX887_000298"
     CDS             complement(47754..48773)
                     /locus_tag="JX887_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAX1256314.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(48946..49833)
                     /locus_tag="JX887_000299"
     CDS             complement(48946..49833)
                     /locus_tag="JX887_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAX1256315.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(49910..50455)
                     /gene="nusG"
                     /locus_tag="JX887_000300"
     CDS             complement(49910..50455)
                     /gene="nusG"
                     /locus_tag="JX887_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAX1256316.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(50556..50726)
                     /gene="secE"
                     /locus_tag="JX887_000301"
     CDS             complement(50556..50726)
                     /gene="secE"
                     /locus_tag="JX887_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAX1256317.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(50750..50902)
                     /gene="rpmG"
                     /locus_tag="JX887_000302"
     CDS             complement(50750..50902)
                     /gene="rpmG"
                     /locus_tag="JX887_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAX1256318.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            51064..51708
                     /locus_tag="JX887_000303"
     CDS             51064..51708
                     /locus_tag="JX887_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAX1256319.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(51764..52267)
                     /locus_tag="JX887_000304"
     CDS             complement(51764..52267)
                     /locus_tag="JX887_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAX1256320.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(52280..52326)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
BASE COUNT        16064 a        10618 c         8885 g        17097 t
ORIGIN      
        1 gctggcacac ggactcatac ctcatttctg agatcgcaaa tatattataa caagaagtga
       61 ggaatattta aatggcaaaa aaagttatgg gtcaagacgg aaaaatgtat aaagttagta
      121 aaccttttta caaaaaagta tggttttggg tattagcagt aattttaatt ataattattg
      181 gttctgcttt aaatggtgga tcagatagta ataaagcaag tgataatggt ggcgaaaaag
      241 taactaaatc ttcaacctct gcttcatctt ctaaagaaga aaaaagcgat accttctata
      301 agattggtga cactgtaaaa gttggtgatg ctgaatatac actaaatagt gtagaactaa
      361 ctgatgaaag aaatcaattt gaagaaaacc aacctgcaca agtagtaaaa attacttata
      421 ccgtaaaaaa tgatggcgat tcagatatcc ctgtaggtac agatgtggaa gtatatggac
      481 cagatgacaa aaaatcagag acatatgcca acgaaaatac aatgggatct gttgctccag
      541 gaaaacaaat ggatgtaact gctcatttca cgttaaacca aaagggagaa atagaaatcc
      601 acttctctcc tttagtatca tttgaaaaag cagctatttt taaagcaact gtataataaa
      661 taaaaaacac gccccaccgt ccagagtaag agcgtgcttt tagaaaacaa acctatatag
      721 gtctatttgt tatgcctatt atagcaaatg ataggagatg ttaaaagtgt gggttgaaca
      781 aaccaaagat ggccaattca agtttattga aagatatgta gatccttata cagaaaaaac
      841 acgaaaaaaa tctacaacac ttacaagtaa ttcaccacaa gcgtggaaaa aagctcagaa
      901 aattctagat aaaaaaatta aagaagcact cgaaaattac aataaatcag atatcacttt
      961 tggtgagctg tataaagaat ggtatgaata ttataagcag catgttaaac gtactagcta
     1021 tttgaaggtt ccaatgatga tgaaacatgt ttctaagcac ataagcgatg atacaatcgt
     1081 tagaaacatt gatgagacac tcattaataa gatgattgaa gatatgtaca cttttggtga
     1141 tctctcactg aactacacaa agcaaacaaa aacaactcta tccgttatgc taaactatgc
     1201 aattgataga aaatacattc aaagaaaccc tgctctagca gttaaaatcc atcctaaaaa
     1261 agtggaagaa gaaaaaagaa agctttctat ggataaaaaa tatctggaga aagaagaaat
     1321 tgatcaaata ctgaaacagt tatattccaa tcctcgcaga aaactacacg gcataatagc
     1381 tgaatttcta tatttgactg gtttgagata tggggaattg ctggctttgc aaatgaagga
     1441 ctatggagag ggtaaaattt ccattaatgg gaccttagat tacacatctg taaaaatgga
     1501 taacgccata aaaacaactc caaaaaatac ttactcacaa cgtgaagtac aattatccaa
     1561 tcgtgcaaaa gaattgattg aaagtgtgat agctgacaat attcttgcag gtagacccac
     1621 caatcccgat caatatatat ttatatctac aaatggcact ccgcttacgc tgcactcatt
     1681 taacgctgta ctccataaag tagaagaaga gttggaatta gaaaaaaatc tatcatcgca
     1741 tatatttaga catagccatg tttcgctatt atctgaatta ggcgtacctc ttaaagccat
     1801 tatggagcgt gtaggacatt ctgatgcaaa tacaactctg tctatttaca atcacgtaac
     1861 caaaaaagca aaacaacaag taattgataa actaaatagg ctttgatatt tctgcccctt
     1921 ttttgcccct tttacttaaa ataaaacaaa aaaagaaaag agaaccctgt aatataaggg
     1981 ttctctttta attcctacat cataccgccc atcattgatg gatccattgc aggagctgct
     2041 ggcgctgctg gttctggttt atctgcaacg actgcttctg tcgttaataa caaggcagaa
     2101 acggaagcgg cattttgcaa ggcagaacgt gttactttag ttgggtctac gatacctgct
     2161 tcaaccatgt ttacccattc tccagtagca gcattgaaac cagtgcctag ttccacgttc
     2221 ttcaatttat caacaatcac tgatccttca taaccagcgt tttcagcgat ttgacgaatt
     2281 ggttcttcta aagcacgaac aacgatcttg atacctgttg ccacgtctcc ttctgcttct
     2341 acagcagaaa ctttgctgat aacgttcact agagctgtac caccacctga gaccattcct
     2401 tcttctactg cggcacgtgt agcattcaat gcatcttcaa tgcgtaattt taattctttc
     2461 aattctgttt cagtagctgc accaacttta acaacagcta caccacctgc taatttagct
     2521 aagcgttctt gtaatttttc gcggtcaaaa tcagaagttg tttcagcaat ttggtttttg
     2581 atcaattgca cacgagcttc gattgcttct ttttctccag aaccttctac gatcgttgta
     2641 ttgtctttat ctacaacaac tttagaagca tttcctaagt tttcgattgt tgcatctttc
     2701 aattctaaac ctagatcgtc agtaattact gtaccacctg tcaaaatagc gatatcttca
     2761 agcattgctt tacgacgatc gccgaaacca ggagctttta cagctactac gttgaatgtt
     2821 ccacggattt tgttcaatac aagagttggc aatgcttcac catctacatc gtcagcaata
     2881 atcaacaatg gacgtgattg ttgcaagatt tgttctaaca atggcagaat atcttggatg
     2941 ttagagattt ttttgtctgt gatcaagata tatgggtttt ctagaacagc ttccattttg
     3001 tcgttatctg ttaccatata ttgtgataag taaccacgat caaactgcat accttctaca
     3061 acatctagtt ctgtttcgat cccttttgat tcttcgattg tgatgacacc gtcgtttcca
     3121 actttttcca ttgcatcagc aatcaaatgt ccaactttat cagaacccga agaaacagct
     3181 gctacttgtg caatggcttc ttttgaatca acaacagttg agatattatg caattcttcg
     3241 actgctgctt ttgttgccaa ttcgatcccg cgacgaatgc ctagaggatt agcacctgca
     3301 gttacgtttt ttaaaccttc gcgaacgatt gcttgtgtca gaacagttgc tgtcgttgta
     3361 ccgtctcctg caatatcatt tgtttttgat gctacttctg atacaagttt tgcacccatg
     3421 ttttcaaaat gatcttctaa ttcgatttct tttgcgatcg tcacaccatc atttgtgatc
     3481 aatggagagc cgtaagattt ttctagtacg acatttcggc ctttaggtcc taatgttact
     3541 ttcactgtat ctgctaattt atctaccccg cgtaacatag ctgcgcgtgc gtcttctgca
     3601 aatttcaatt cttttgccat gattgattca cctcattgat tatttttgat tattttttta
     3661 tcttccaaat ttactcaaca atcgccatga tatcttttcc tgcgacgatc agatattctt
     3721 ttccttcgta ttttacttct gtaccggcgt atttttcgaa cataacttgg tcgcctgctt
     3781 ttacagcggc aggaactttt tcaccgtttt ctaacaaacg gccttcaccg actgcaacaa
     3841 ctgtcccagt ttggggtttc tctttagcag cagaagctaa aacgattcct ccgacagttt
     3901 tttcttcttc ttttgcgact tcgataatga cgcgatcacc taatggtttt aacacgataa
     3961 atccctccga taactctttt tttaatctgt tagcactctt aaccttcgag tgctaaccta
     4021 catttttaat aatactcatt ctccctcttt tttgcaagct tttaaatcaa agaaaagaaa
     4081 ttttattctg acagctgctt attgaaatta tgatataatt gaaatcaatc gatataagct
     4141 tgccttgcat gcttgttatc ccttaaaagg aggaattaca tgtctttaaa aaaatatagc
     4201 ttcctcagca ttttttgcta tggtctaatt tttatctcac ccttgatcct agcttcgata
     4261 ggacttgtaa aatctacgtc tgaattgatc acagcaactg cagtcatgta tatactaggc
     4321 gccgttgtcc tagctatttt ttattttaag caacgtgaac ccttagcgat cgaatcagcg
     4381 gtaaaaaaag cttctgctcc aaagattgtt atttatggat tggttggaat ctttgtcgca
     4441 ttgattctgc aaagcatcgc tgtcatgtta gaatctgtat tgtttggcaa agcaacccct
     4501 tccgagaata cacaaaatat catccagatg atcatggaag cacccgcttt tattttggcg
     4561 acaactgttg ctggacccat catggaagag ttcgtattcc gccgcagtat actggggatc
     4621 atcagtcgat attcaaattt ttgggtcgga gcagtgatca gctctttgct gtttgcgttt
     4681 gctcataatg atggtcatct gctaatctac tttttcctag gtttcttctt cagcctagag
     4741 tacaaagcaa ctggtcggat ctggacatcg atgatcacac acgtaggaat gaacacatta
     4801 gttgttcttg ttcaattagc tgtccaaaaa gggctagtat aaacatgact ataaatactc
     4861 ctgtcatcct agattggtga ttttcccaat ctaaagcgac aggagtattt ttgtttttta
     4921 gtcgttcatc ttttctgctg ctccatcatt ttttgtctgt ctttcctttt tgcagtttgc
     4981 agaatctatt tttttcaaaa atgggaaata aatgaaaaaa ctaattgaca acacgatacc
     5041 ttgtaaaatc gctgcaggca ctccgcctac taagaaaccc gagaggatcg gcggtgttgt
     5101 ccaagggact tggactgctg taaataaagg aacgaatcca aaatataaag cggaataggt
     5161 aatcaatcct gaaacgaccg gtgcgaaaat aaaaggaaca gccatcatcg ggttcatcac
     5221 gatcggtgtg gaaaaaataa ttgattcatt gatgttgaaa aaggctggta aaagagcaag
     5281 atttcctaat tctctgtatt tcttcgattt cgcaaaaacc gtcataaaaa atacagcccc
     5341 taacgtcaat ccagcacccg taaccgtcat gaactgatcg agaaattgct gagtaacgat
     5401 atgtccgcca tttgccaccg tcaactcttg tcctgaggct aagatttctg catttgctaa
     5461 tgaattcgct tgcaagacgg gactaaccaa cccattgacc atcgcagatc catgaagacc
     5521 aaataaccat aaaaacggaa caaaaaaacc taataaaagc acaccaaaca acgtgtctat
     5581 gaacgattga atgggaagct ggacatatgt ccatactcct tgaacaacag tcattctgaa
     5641 caaatgttga aaaaccgctg aaccgataag cgtaaaagtg actataacaa tgattggaat
     5701 caatgaagta aaagactgcc aaacattttc aggtatcttc tctctttgct tccacccttt
     5761 cgcaagtctt actaaacgtg catagcccca tccgatgatg agcccagttg taactgctcc
     5821 tagtatccct tcagcacctg tccagacagt atctatctga gtatttagtg gctgaataag
     5881 cagtagataa gcagacaagg ctgttatgcc gactggtaag cgatcgatgt cttcttcttt
     5941 tgcataagcg tatgcaatgg caaaaacgat ccaaaaggct atcacatcaa atgtagcctg
     6001 gtatacttgt gtaaaataca tagaaaatcc tgttttgtct atccactgag cgatgtaatc
     6061 cacaggaaaa tgagcaaata agaaaaacag cgagccaaca ataattattg ggatcgtgta
     6121 agtcattcca ttacgcaaag cagttaaggg tctaagattc acaacagatg ttatcattgg
     6181 taaaaaggca cgatctaacc actctttcat ttcttatctc cttcaacttc tatttttatc
     6241 aatcagtttt cttaatttaa ctatacccaa tgatcacgaa ccatgaaagg aatgcgcact
     6301 gagcttttca aaaatcggat tctttgacga atattcagca actgcttaca atggacagga
     6361 ataaaaaagg aggtttttta tgaaaattgc actcattgga gctactggcc atgcaggttc
     6421 atttatttta gacgaagcat tgtccagaga tttagacgtg acggcaatcg tgcgtcatcc
     6481 agaaaaattg ccatcagatg ttccgtttat acaaaaggat ttatttgagt tgacaactac
     6541 tgatcttgca tcttttgatg ttgtcgttga tgctttcaac gctcccaaag gaaaagaaga
     6601 aatgcatcaa acttctttgt cccatttgat tgagatgctt gaaggaaccg atacacgctt
     6661 aattgtcgtt gggggtgcct cttcgttatt cttagataca gaaaagacga ctcgtatgat
     6721 tgaccaagta cctaaaaatg cacccttcta tccaacagct ttcaatatgt acgaaggatt
     6781 gttaaaattg aaacaatcta aaaatctaca ttggacttat atcagtccag cttctttatt
     6841 tgatccacat ggcaaacgta caggtactta tttgttaagt gatgattatt tacaaagaaa
     6901 cgctgctagc gacagtacga tcagcatggc agattacgcg attgcattag tagatgagat
     6961 actggatgag aaacatgaaa agcagcacat cagtgtagtc agtcgataat acggttattt
     7021 ttttaatatg ctaaaaaaat aaaaatagaa gataaaacca accctgattg attttatctt
     7081 ctgcttttta tatttttatt gattgaactg tttaaatcga aaatagctca gttgcttcat
     7141 ctggatctgt atcatagatt tcaaaatcat gtccaacgcc aaaatctttt tctttcaaaa
     7201 cattttccat tgttaaatga gcaagttctt tcatattgtt ttccttgcta agatggccaa
     7261 gatagattcg tttggtccga ttaccgatca catcagtcat gacaagtgca ccgtcttcgt
     7321 tggaaagatg tcctctatct cctaaaatac gctgttttaa attccacgga taaggtccca
     7381 tgcgtaacat ctcaagatca tgattacttt ccatcaaata accatcggca ttttcaatga
     7441 cacctcgcat ataatcactg caatatccgg tgtccgtcaa catgacgaat gaccgatttt
     7501 ctttatggaa acgataaaat tgcggagccg ctgcgtcatg ggagacgccg aaactctcaa
     7561 tatcgatatc gccgaatgtt ctgactttcc ccatctcaaa tagatgtttt tgttccactg
     7621 gtacatttcc aatcagtggt tccatcgctt cccaagtctg ctgattggca aaaacatcca
     7681 aatgatactt acgagccaag acacccacgc catgtatatg atctcgatgt tcatgcgtca
     7741 caagtattcc atctaattgg tccggtgtcc gatcaatttg agccatcaag gaagtgattt
     7801 ttttaccgct aagtcctgca tcgaccaaaa gccgtttttt ttcactttcg atataaagtg
     7861 aattacccga acttccactt gctaggatac tgattttaaa agctggtttt tcttcagcca
     7921 tttgactcct acttcccttc ttactttgta aacttttttc attatactcg cttttttatt
     7981 gatcttccac ttttggtaca gtattgtttg tcacgatcgt attgctgaaa gcgttgacgc
     8041 tctcaatttg gaccacttta tcgcttgttt cgatcgctac atgccaaaca ggaacataca
     8101 catttttttc ccggactttc agaatacagg aataagctag ctgacgccat aaaatttttg
     8161 atcctcttgg tattttgtta ttgatgtaca atgtattgat tgcttcctct tccgtataca
     8221 gttccgtctt ttcgcgcagc tgctcgatat cagataaatg cgtctgcatg tatttcgtga
     8281 tgctataatc attatcgttt ttttctaaag aaagaacgat ttttgctgta tcatcattga
     8341 atgggatgcc ttcatactct tggcttgctt ggatttctag tggttcttct tctaaatgag
     8401 aaaagttttt cgtgtacaca taatcattac cgaataaaat attgtctttg ttagataaaa
     8461 aatcttccaa ggaactacta attttatctg gatcgatcac gttcttttca gcatctgaac
     8521 tggataaaga tttcgtcaaa acatcaccgt ctaaaaacac accacttgcc agcaagccgc
     8581 ttttaccagc cttgcgataa ttcgctaatg aagtgctaag attggtctgc tccgcgctaa
     8641 gataatagcc ttgcttgttc tcagacgaaa tcttccccgt gtaagtgata tcgtcgctag
     8701 ccagacgttg ttggattgat tcagtctgat tagagcgaat gacattgttt tcttggtata
     8761 ccgcgtcatg ataactgctg aataaaaaca cattcaaccc taaaaaagcg acgaaaaata
     8821 tccattcgat ttttttgaaa tccaattaat tcgcctccaa tccaggtaat ttttccagaa
     8881 ggtcgttagc tgaataccag ttatctttat atttcacata ccattcaggt aagagatcaa
     8941 cgacacgatt cgtttctttg acattttgcc atgtatagcc aacgatcact gaaccaatct
     9001 tgttgctatc tgctccctta gcttttaact gctggatgat ttcattcgta cttgcaagtt
     9061 ctacttcttc gtctgaaggt atcggcactt gaatcgtatt caaactggtt tggatattca
     9121 cttgcacaga accattcgtt tcaccgccaa cttccacacc aatctgtcct ctgctgtctg
     9181 tcccaaaaac cgggaagcct tccacgaata tccgataatc gatcgtattg tcactgcggt
     9241 caaaatatct gaggttccct aaagaactgc ctaatttgct aatatagggg aaactttcag
     9301 aaaatacact agcattttct tttttctctg gcagctctcc acgaaaatca actacttgcg
     9361 tttccgaatg gatagacatt gtttcattcc caccgtaaaa aatcaattca ttgctttcat
     9421 cattattttt cacgctatct ggtttctgga aaaaagcatt tctaaaaagt gtatagggtt
     9481 gctgtgacag gatataacta tacttcttca gtttgatcga atgtttcgta gcatattgcg
     9541 tgtcgatcgt cgatggttct gttgtcattt ctgtccattt tgtgtctttt gctgttaatt
     9601 ctttattgat atctgtccaa ttcaacgaaa tatttgcttc atatacgaga tggttcgaat
     9661 aattcaaaaa tcggattttt ttatttcctt gatcgaattg tattctagta aaatacatat
     9721 tttcgctttc ttttgccaag ttcgacacat ctaaatctaa atcaaatgct tccttgtatt
     9781 ctcttagcaa aaaaggcgca ttataggcca actcaaaacc agagttcaga tttttcacct
     9841 gttcaaactg tgatttgtct cctgaaacta cttcagaaag ctttccaaat cttgctttat
     9901 cgatgatcaa ttgcaatcgg tacacgagat tttcactgtt ggtttcttgg atcattcccg
     9961 aatggtgcca tgtaacatga agcggaagaa agacttcgga agtttttcga ttgctttgag
    10021 actcgatcat ttgagtgttt gtctcatcta cgttgattga actttttcct gctgggctca
    10081 gccagattgc ataagagaag tatatgctta acgcaaccat caaaatgagt cctatacgaa
    10141 cgactttttc agagattctc attcccacca ttcctcctca taaggttcat atggcagcga
    10201 gatataaaaa gtcgaccctt ttccttcctt gctctctgcc caaatagcgc ctcgatgcgc
    10261 cttaatcact tctctagaaa tagctaatcc aagtcctgtc ccaccttgtg ctcttgcacg
    10321 tgctttatct actcgataga accgctcgaa cactcggttc agatcttttt taggaatccc
    10381 caatccttga tcggtgatac ttaaaatcac gttattatgc gtttctaata agcgacaagt
    10441 aatcgttccc ccatctggtg aatacttgat cgcgttattc atgatattat cgactacttg
    10501 gatgatttta tctgtatcta cttcgaccca aagatctctt tgcgtaaatt cacgacggat
    10561 cttataattt ttttcctgat ttcccaccat catatcaaac cggtcaagaa caaaattcac
    10621 taactcgttg aaattgacat attctaattg aagctgggta ttacctgtat ccatgcgaga
    10681 tagatttaag aggtcattga tcattcgaat cattcggtct gtttcatcta gcgttacctt
    10741 caaaaaattt ggtgctactt cctcgtcttt ccacgcacct tcgctcaatg cttcgatata
    10801 actacgcata cttgtcaacg gtgtacgaag ttcatgggaa acattagaga cgaattcacg
    10861 acgttcccgt tctgtttttt cttgttctgt cacatcatgc aagacagcta ctaatccgct
    10921 gataaaacct gattcgcgac ggatcataga aaagtctact cgcaagatca tctgatcact
    10981 ttccaatgta ctggttgaac ggtcaagtac catttcgttt ggatcttcta ataatttccg
    11041 caacgtatat tcttcttcga tatctaaaag tgtcaaaatc gattgtccga ttgcttcctc
    11101 gtttttgata tctagcaagg aaacagccat atcattgatc gtaatgactt tacccctgcg
    11161 atctgtcgca atgacgccgt ctgtcatatg ggatagcacg ctatccaaac gattgcgttc
    11221 agcttccatt gtatcttgag cttcttcaat acgttcagct aactgattga aggtatcagc
    11281 cagctgtcca agttcatctt gtccatgcac tttgactttc cgactgtagt ctcctctagc
    11341 gattcgaatg gcttgttctc tcatttcacc gatcggctgt gtaatcgaac gagcaactaa
    11401 aacagatacg atcattgaaa taaatgccgc aattagtgag gcagtaaaga aaatgactgc
    11461 tgtgttattg atttccgaat atttttgttc gatattactt ttgacgtaaa gagccccgat
    11521 aacggcatcg ccggtcgggg acaggatcgg ttgaacattg atattcaccc gtttatcgtc
    11581 gttatctaaa gcaacataac gtttagtcgt gaaatcattg atatcaacat aatcattttt
    11641 ctttcccaca gcgctttgtt cattgacatc ggttgttcct cggatgatcc ctttttcgtc
    11701 aacgacccgt atttcgatga tatcgctagt cgcactgttt tcaataaatc ttttgatatt
    11761 cgcatttacc tcttcatcat ctgcattatc ttttcgattc aattccgggc tgattgttgt
    11821 tgctaatgat tccaccgttt gattcatatc tttaataaat gtattgatcg tggaacgttc
    11881 taaaccacgt ataaagtagg caccaataat ttcgatcgag atcaataaaa tcagaataaa
    11941 ggtaatagcg atcttaaaat tgactgatcg aaaaaagcgg acttttcttt tcatccaatt
    12001 actcctgttc tgggttacgc aaatagtaac cgacaccacg acgtgtcact aaataatttg
    12061 gatggcttgg attatcttcg atcttttcac gcaaacgacg tacagttaca tccactgttc
    12121 gtacatctcc aaaataatca taaccccaaa ccgtttgtaa taaatgttct cttgtcatca
    12181 cttgtccaag gtgcttcgcc aagtaaaaga gtagttcgaa ttcacgatgt gttaactcga
    12241 ttgtttctcc tcgtttcgtc accatgtaag cttctggatg gatcgtcaaa tcaccaatcg
    12301 tcaattccgc aggtgctgcc tcttctggtt ccttcgcagc cgtggcaccg cgacgaagat
    12361 ttgctttgac acgtgcaact aattctcggt tggaaaatgg cttggtcacg taatcatcgg
    12421 cgcctaactc taagcctagg actttatcaa tttcagaatc tttggctgtt accataatga
    12481 tcggcatatc ataagttttg cgtacctcac gagcaacttc taagccgtcc attttaggta
    12541 gcatcaaatc aagtaaaatc aaatcaggtt ctacctcagc aactttttcc aaggcttctt
    12601 ccccatcata tgcagtataa acgtcatagc cttctttggc taaattgaat ttgacgatat
    12661 ccgaaatcgg cttctcatca tcgacaacta aaactttttt cataaagagc cacctcttat
    12721 atattattgt cataccttct cattataccg tatttctgct tttgtttcat ctttgcctat
    12781 aaaacaaaag agaaaattaa aatgaaagtg caaaatactt tattattttt tgttctaact
    12841 tcaataaaaa aggaaaacac tgattttcac ctcagtgttt cctttttttg atttatcctt
    12901 ctaaaacttg tacaccgaca cccaataatc ccggaccagt gtggactact aatgccggag
    12961 aaatctggcc aaagtagatt tggtttgctt gtgggaactc tcttttaagt ctcgcttcca
    13021 tttcaattgc ttcttctttc gcatccccat gggcaacagc taagttgaag acctttgcat
    13081 taccgatttt ttctttgacg taagcaaccg ttttatccaa acttttttta cgtcccctag
    13141 cttttcctac tgtgtaataa atcccttctt cattacatga gatgattggg ttaagcttta
    13201 aagcggttcc tacaatagaa gcaactaaac cgatccgtcc acctttttga agatattcca
    13261 atgtcgcaac attaaagaaa acttttgttc tttcgactaa ctcattcaga ttactgatca
    13321 gttgatccca ttctactcct tcttccagcc attttgctgc ttggatcgca gaaaaacctg
    13381 caccaatacc aatatttttc gtatctagta catatgcttc caattcttct tgctgttgtg
    13441 caattaaacg aaccacatta tatgtcccgc tcaatccact ggaaattgtt accgcaagta
    13501 ccttttcata accgtctttt ttgatttgct caaagatttc tgtgatcgac tcaccatccg
    13561 gcaaagatgt accagggatt tcctctggca aacgttgata gatctcttca ggggtaatgt
    13621 caattttatc tgtatatacc tgatctttat aaataatttt caatgggatc atatacatct
    13681 cgtatttttt tatcaattct tctggaacat ccgtacctga atctactaaa attgcgattt
    13741 tattgttttt catttgtttt ctcctctttt aaatattcgg tttctagaac aatcgttttt
    13801 tccgcaagaa gtttcattgc aaacgataaa gttgccgctc ttacagcaat atattctaca
    13861 ggggttgcct ggtcgaattt ttgcggatga gatttacctt gtgctaattg gctgaccatc
    13921 cacacagctg cttcttgttc atcgcaaaat agattatagg cttcacgaat tcctactgtt
    13981 tttccttgga acaatatccc ttctttgatt tcaggaatag tcaatacttg tttcaacgta
    14041 gtgattgcaa gtaaaaatgc tacgtgttct ttgttatatc tttttttaac tggtgctggt
    14101 atcaaaccta gtttaacgta attgtttacc atagaagagg taagcaatgg atgcttttct
    14161 ccttgtatca caggtgaaag ataacgatca actaacgttc tgacttggtc catataaagt
    14221 tctaagtcag ggagttcttc ccagtgaggc agacggaatg tttctagttc cttcccccac
    14281 tccattaatt gctgacgcat tttttccatc ataaccgctc cttttttcat ttcataaaca
    14341 tgatatcaga cttatgataa acattcaatc tagttgcttt aactaggtga tttgattagc
    14401 gggattccat gaaaacaaaa aacaagaagg ctaagccttc ttgtctttta tcgttaagaa
    14461 caggagaccc gccggggaga cggcgggaaa ggagtaaaaa atgaaaaaag tgttagggtt
    14521 tgttctcttg caagaacttt gtttgttggt atgcttatat aatagcgagc aaatgtgaat
    14581 aatctatgaa tgatttccta taaggaagta aagatttttc tgattttctt taaatgtagt
    14641 cttgcatttt aaaattctta gtgctactat tattaagtac tttttgtacg ggccgttagc
    14701 tcagttggta gagcagctga ctcttaatca gcgggtcgcg ggttcgagcc cctcacggcc
    14761 cattgggtgc caaacccacg gaacaggtaa atgttggtgc gaaagcattt cgaaaacatt
    14821 tacgctgttc tttttttatt tttcaaaata actagggctt tttattttta actcaaagtc
    14881 cactgtagcc ctttggactt tgagttaaaa aagaagcata attatgaaca gtaaagtttc
    14941 taatataaca ataattcgag aagctttgca aaatcatgct gccaatgaac tctctaaaca
    15001 tataggatta aatctaagta ctataaaagg ttaaaaagtg aagaatattt aatagaaaaa
    15061 ctaaatttac ttgctgcttt ccccttttcc attaatacaa caatcagaga gtgtcttttt
    15121 ttcgaaaaaa ttagaataaa taaaagacac gtagtttttt tatctacatg tcttccatcg
    15181 actacaagtt atcatttctc aaaacgtatt tagcttttaa ttgattaatc gtttcacgtt
    15241 gtctacacat tgcctaatta agattttctt attagaagca tcaatcccgc aataatacct
    15301 aaaactccag gaattaccca caataatgtt aaaagaaaaa atggaataat agataaaatg
    15361 agtaaactaa taccatagac cactgttttt tgattttttc ttactaaaaa acctattatg
    15421 aaaatcatta tcgaaaaaac tagggtaatt cctccaaata aaacaacatt cccgcttaga
    15481 ttgactaaca tatctatatc cttactggtt agttctgtag tatttaaagt agttgaatca
    15541 atagaagata gaaacatacc acccatcaat gctaaaagac tacataaaat ccctgttatt
    15601 ccactaatta aaatcaaaat aaactctgtt tttctcttat tcatttaatt ctctccagat
    15661 taagtgtttt agaattagaa attttttgac catagttaat agcttctaat gaacgaataa
    15721 caaccactga cgtgttagaa aaataatccc caatatgttg tttcttgggc gtgaaagcag
    15781 ccaccaaata cccaatttga aatacaaaat tttttaatat aaacctacat atacactcac
    15841 gaataaagat agtttgccaa cttagctctt tttcctcaaa gctcactact cttatcccaa
    15901 aaatcatttt cccaattgtt tgtcctgaat tcagcttagt caaaagtaca aaataggtta
    15961 aataaatagc taatgacgct ataccataaa aagtaataat ggatttgtca gattccagtc
    16021 ccatgatttt gtaaaagaga cctatagtag catgggtgat gatgctaata caaattaaat
    16081 caataagaaa agcaaaaaat cgtaaccaaa atcccgcaaa tacataatta ggcaaagttt
    16141 caatgccact cttcttattc attttatagc cctccatagt aatacattgg ttttggagta
    16201 tcagaaaatc caagtttttc aaaaactgaa attacacgat ctgatgtagt tgcctttagc
    16261 ccttgccatt cagcaatctt attacctaac caagaagaag caaagccagt tgtgtcattt
    16321 ttatattcta taaccgtcgc atcagttaat ttcttctctt tttttaggga atctaatgca
    16381 tcttcagagt aaccaatttg atccaccaac ccattttcta ctgcttggtt accatcataa
    16441 attcttccat ccgcaagttc tttcactgca ttagtatcca tatttcttcc ttttgctaca
    16501 acattgacaa aacgatcata agcactcatc acaaattcct gtataacttt attctcttcc
    16561 tctgaaggtt tgtgttgagg tgacatcata tcttttaatg caccactttt atacgtcgca
    16621 tcagttacgc caagtttttc taataagcca gaataattta aaccagaaat aatgacacca
    16681 attgatccag ttgttgtttc ttccgtagca aatattttat ctgaaccagc agaaatgtag
    16741 taccctccac ttgccgctgt atttttaaat gcagtataga taggaatatc tagcttttta
    16801 atttttgcca tttctttagc aatctcagca ctttcatata ttcctccccc aggtgaattt
    16861 acttctaata acactccctt aaccgctttg tcttcttgaa ttttctttag ctgtgttaaa
    16921 aaattctgat ggttatattg ttccctacta aaaagattgc tttcacctgt atctgcaata
    16981 actccattga cggatagttt gacaatcttt ttatttgatg cgccttcttc taacgtttct
    17041 tctgtgattt cgttagatcc gtaaaaaatc ttatttattc ctgttagggt tgtatttgat
    17101 gcttcctctt tatcttttcc tggaattagc gcgacgataa tggatagtaa caataatccg
    17161 cacgctactc ccacagcaat ccatcttctt ttattcatat aaactcctcc tatattctta
    17221 gtaaaaataa ttatttttta tttagaaaca catcgacaat ttgttgccaa tatgtttttt
    17281 ctcctacaat taaagacaac tctccagtta atccataacg aaacggaaac gattgagttg
    17341 tttttaacgt tcctttcact gcataaaaaa cacctttctc agtggcagta gaattttctg
    17401 aaatttcatc taaagttccg tcgatcgtaa tcggagcccc acctttttga tccaatttaa
    17461 aatgaacctt catcccttct ttaatatagg tactttcatt cgcaggtaaa agtgctgtaa
    17521 atttcatttt tgatttttcg tggatcggat aaatttctgc aagcactgtt cctttggcta
    17581 gttctgcttg tccctttgtt tcttcattta aatgaaccgt tccagataca ggagctttta
    17641 gtattccttt tgaaagttga tcgtccaaac ttttgataac tgactggttc ttctcttgtt
    17701 tttcatttag ctctgtaact gtttgtttta cagttgttat tgcttgttct agctcttgct
    17761 ttcctttttc cgtttgacta attctgtcat tctcagaagt agttggttta actaatttag
    17821 ctttttctga ctgatactgt tctacttctt tttttagttg ctcaatttgt tcatttatgc
    17881 ttgctgaaat tgtcagtttc acttgatttt tttgatcatc agaaacatta tttagttgtt
    17941 cttgccaatt ctcatagttt gccatcattt cttttgaaaa atcttttaat gattgattat
    18001 tactccaagc tacctgtact tgttgccatt cttgtaattt actatctgaa ctctcaattt
    18061 gtttttctag ttgtcttttt gtcttttcgt atacttctaa ttgcttttga tcatttaatt
    18121 cactttgctt caaagcgtag cggagtgatt ctttttctga caacatgctc tttaattgat
    18181 tactgtagcc aaaactgtca tccgttgaaa acaaattttt tcctttactt atactttcaa
    18241 taaatagctg agccatcttt atttgttgag taatacgttg gttttcttgt tctatctgag
    18301 ccttttcatt ctctattaaa gaacaatcca atctaaccaa cacatcgtcc ttatgaacaa
    18361 attgattttc ttttaggaag ttttccatta ttttagcttc taatggcact tgtaacttct
    18421 ctattttttc ggggttcaat tgagccgttg tccgaataac aacctctttt ttagcaaagg
    18481 ttaaaaacaa tccaataata cataaaaaaa gaattacagg gtataacacc caacggtaga
    18541 agctatgatg ttgtttagta tagatactag aatgttcgaa ccaattatta ttctgcataa
    18601 attgtttccc tctcctagat ttcccataat ttttgataga taccatcggc aaaacgaagt
    18661 tcatcgtgcg ttcctttttc taccaaatgc ccttcatgga gaactaaaat ttgatcacat
    18721 gcttttgcta ttggtaaatg atgcgcaata aaaataatcg ttttttcttt taaattgagg
    18781 agataattca taattgcatg ttctaacaag gtatctaatc cactagttgc ttcatctaaa
    18841 attaatatgt ccggattttt taataaagcc cgtgctaagg ctaatcgttg tcgttgccct
    18901 cctgaaagat tatttccacc ttcttccaac aatgtctcgt aacgtaatgg ctgttgatta
    18961 ataaattcat ttagttggac tatctcacaa acttctatta tttgttcgaa acttggtggg
    19021 ctatctaaac cgaatataag attctcaatg attgttccac taaagaaaaa tgactcttga
    19081 ggcaaatatg tcactcgatc gcgtaatatc tgaaaaggaa tgtctaagtg attaatgttt
    19141 ccataatgga tcgatccttc tgatgcttca taaaaacgaa caaataactt tgcaagagtt
    19201 gattttccag aaccactaac tccaactata gccgttttac tgtgcgaagg aattgtacat
    19261 gaaatttcgt tcaacgttgg ggccttcatg ctatacgaga atgaaacgtt ttttacagtg
    19321 atatcttgtt gaaataattg ttcagaaagc atatattcaa aagactggtt cgatttttct
    19381 gaatcaatcg cgaaaatttc atttaaacga ttatttgcaa cttgagccgt ttgcattttc
    19441 acttgtaaat taataatgtt ttgtaaagga tctgtcaaaa atactagtaa agcattgtat
    19501 gtgataagtt gacctagact aattctatta tccataacaa aataagaacc tagccataaa
    19561 attaatgcac tgctaattaa ttgaatcaaa tgtttaattc cttgttgaat attatcaagc
    19621 gtaaccgtac gaaatgattt tttcattaat ttaacaaatt catggtctat acggttatat
    19681 actttctctt caccgctata tgctttaatt gtttctattc ctttaagact ttctatgata
    19741 ctagaattta cagctgcacc ggctgccatt tcttccctgt tcgatttttc atagcttttc
    19801 acgaaagcga atattgcaac tacataaaaa ggcaaagagc atagagtgat taaaaacaac
    19861 gtactattct gaatagctaa cgtaacccca acaagcaaca ccataccaat atctaaaaat
    19921 attgataacg tagcacttgc taaagcatca ataatcttac tggcatcaag aaaacgagaa
    19981 ataatttccc ctgattttct cgtagcaaaa aaattcattg gtaaagttaa cacatgtttg
    20041 aaatactgaa gcataattgc catactcatt cgctgtccta aaataataag aagataacta
    20101 cgactatatt caaacaatac ccgaaataaa tagacagcga tcaagccaat ggaaattata
    20161 tttaaagttg aacgtgcttg attagggatg aaaaaatcaa gaataccttg aaaataatat
    20221 gagcttccta tgccaaaaaa cgtaatgaaa atcgatgcta aaacgatgtg gaatactaat
    20281 cctttttgtt tccaaattat aggcaaaaaa gaacttaatc cagctacttt ttctttaata
    20341 ggaatataag tttctctagg cataggtaat aaaagaatac ctgtccattc tttttgaaac
    20401 gcttcaatcg tttttctatt ttttccatta gcgggatctg caatccatag tacgtttccc
    20461 ttcgttttat aaattacaac gtagtgcata tagctgttat caaccaatat atgtgcaatt
    20521 aatggtaaga taagatctct ttctttccag atctcactat ctgcttgaat agccatacaa
    20581 tcaaaagaca atttttcaaa tgtctttttc aatccaaatg ctgaagtacc ctctaaatca
    20641 gtcccagata ggtcccgtaa tttatgaatc gggatatcag ttttaaaata ttttaaaatc
    20701 atcgaaaggc aagcaacacc acaatctttt tcatcttgtt gctgcacaaa aggaaatgat
    20761 tttatcactt atctaacaca actccttcta aaaaattttt atagaaaaat tctcaatata
    20821 gctttaatac agtgaaaata ttgtctcata attccacaaa aactttgaaa acagttcttg
    20881 aacactaact ttttcattcc tgaatcaaat ttattttgga aattttacta ttcaagaata
    20941 aacttgataa gtttcaggaa gatttttact gttaatcaaa tacgtatgtt acagtagcac
    21001 cgtaaaaaat attatttaaa gaagcgtgtt taaacatgca aaatgtaaag gaactaagta
    21061 ttgtggaaat gcacaaactg ttggtggagg caataatgct tggggaaaat tggggcaagt
    21121 tgtaggtgga cttaccacag gggcagtagg tggtgcaggt ttaggaacag caatttgcgg
    21181 accagcttgc ggtgttgttg gagggttata tggagctgtc gctggaggtg ctgcagctgg
    21241 ctgggatgct cgaaaaaaat aaaaaaggag aataagtagt atgcatatta aaaacacaaa
    21301 aacaacattt atattatctt cagaagagtt gaaaaatatt caaggtggga gtgccgtggg
    21361 agttttaggc actacttttt ctggggcaac agcaggagta aaactttgtt cagccggagg
    21421 accttatgca atagctgctt gtggtgtagg tggagcttta ttaggtgctg gattcagcat
    21481 gtggaccggt gcgtaaacaa ttaaaaaata tcaaacctca agattggttt gtgtcgatta
    21541 cgaacatagg tatgttcttt atcttttcaa aagtttggaa tggacagaac tttttactaa
    21601 agcttcttgt gctagttttt ataattatat taaattttta tcttttatta aagtcagata
    21661 aaaattcttt ggaaatgtaa tggtagagat atttttacaa aaggacttgc agcgctgtag
    21721 ttggtgctgc aggaggacct atttcggccg ttacaggagg tattggtaat gtacttgtcg
    21781 gatgtgcatt aaagcctgtt cctgcaagtt aaatttataa aaacaggaaa gtaattatct
    21841 caaatcctat caagtacaat cataggattg cacttgacag gacaaatttt ttaactaaaa
    21901 aatgaaaaac actttctaaa aattagtaga atttgccaaa tctttcgcat cttccaccat
    21961 acatttaatt ttaattcccc tttatggtac ttaataaaaa caagaaaaga actattcatt
    22021 tggccctttt ttggttccag accatagaaa tattcctcca gtaactaata ttgctgttat
    22081 gcacgtaact aataacagct ataaaaattg gtacaacttt aataggattc agaaaaattt
    22141 gcactagtga aggaatctat tttattagaa aaatgcaatc tccctaaaga aaaaaccact
    22201 aaacagtgct ttctttcaac ttctccttaa ttttttgtgc tttccctaaa gtaaagtttc
    22261 tggccaactc tgaatcaaaa tatagtgaac gttttttaaa atctatttct ttaacgttaa
    22321 agatatttac taaacacgct cgactaattc ttgttaacat aggatatttc ttttcaagct
    22381 cactaattct tccataaaat tcgtactgcc catctttagt acacaatgat aatctatgtg
    22441 gtaattttga agcttctaca aaataaatgt catttatatc aaaagtaaat gtttgagaac
    22501 ctatggaaaa aacaaatgct tgattcgtaa cctgttttgt tgcatctatc ctttcttgcg
    22561 ctaataacaa taactcaaca atctcgtttc gatactcatc tagtgtttga tcttttgtta
    22621 caaatcctaa cgtttcaact cttcttttta ttgttacggg taacatctca tcatgagtag
    22681 ttgtaaaaat gatttttgct tgaacatcat attttctgat tacttctgct aattctatac
    22741 cgttaacttc atgatttaaa tcaatatcta agaaatatat tccttgcttt ggtcggaatt
    22801 gtttgaggta ttttttaact tctaacggac tttgtgtttt caatactatc ttaaatactt
    22861 tatcgtgaaa aagaatgaaa ttatcaataa ttcgttctaa ctgatttaat tgtataattt
    22921 gatcttcaca taatattatt ggataactca taaatcctcc ttccctcaaa acaacaaaat
    22981 aacttgagta gtaaattgat acggatcgtt ttgatagttc acaaacatat tgggattctt
    23041 tttattgatt tcctctatac tagataaacc taacccttga tgtccctttt ttgttgttat
    23101 tccttttttc attagagtat ctatagagag tagtatctct ctacaactat tcgatatcga
    23161 aatttctatc tgtttatcat ctcggtaaat agctagagac agttctctat cttgactctc
    23221 tatagatgct tcaattgcat tatcgagaat aattccaagc accctaatac agtcaaatat
    23281 tggaacagga acttcaataa tagtacttgg acattcgaat ttacaacaaa tcttattgtt
    23341 atttgcttgg tatagcttcg ctatcaacaa acttttcaaa tattcatttt ttatattttt
    23401 taaataacga tattcaaact tattggttag ataagaatta gaatagatct ctaattcttt
    23461 tatttctttt tccaatatcg aatcatggtt ttgattagcg atttctttta aactcagcaa
    23521 taaattttta tagtcatgtc taaatctggc aaatttttct tgatcttttt ccagtgaatc
    23581 agtatatttt tttagataaa ccaattcttt tcttttcaat tgctgttcat attgttctcg
    23641 ttgcctaata gttattctaa taaataaaaa tagaacaaca aacatttgaa tgattaaaaa
    23701 tattaagaca ccaaacacaa aatgatcaaa tacttgatat tgatgagcaa cataagaaac
    23761 aaataaacca attgtaagta aataaatcat gaatatagca gtaagtttag aactggactg
    23821 ttcaacaatc ctatttatag ctaattttct atataaccaa ataaacatca gcaaaaacaa
    23881 agaatcaagc attatctgga atactacata accataccct tttatccctt caaatgaaaa
    23941 catatacgtc ataaccatgg aagtaataat agatctgaaa tcatcaataa gcatacataa
    24001 tagtaattta tttaaaagca ctatattagt tttcttcttt tcctttaata taaaataact
    24061 tccgattata ggtatagctg cggaaacatc agtaaataat tcaacaaaaa aagtgagtgg
    24121 tatcaataaa catacaaaaa gatattttct tttgttaaga tcagtattag tcatataaaa
    24181 taagagaaaa aagaaaaagt ttcccacgaa cattcttaat agataagctt ttgtatcgat
    24241 agtaatcaag agatcccctc ctgattttag gatatcataa aaaaaatttt agttacactt
    24301 tttaaataat gaaaaaacac attccactaa atttgatgcc ggttttcctt gaggttttgt
    24361 tccagcacct cctttaattt ttttaagctc ttgatctgaa cattgtttag catttagtct
    24421 atttttttct tccattacga ttccccctac aaactataaa tacttttatg tcactgattc
    24481 aatataccta tttttctaat caaaaaattt tgagacatat ttaatattat aagtatcatt
    24541 aaaattgaga tttatctcca taatctgctc gatataaacc atttattcca gcagttcttc
    24601 caatttcact caaatttctt attaattcct cttgatattc agtgaatctt attttattag
    24661 tataagcagt aaaatataga taattcacca atctatttat taaaggaccg ggatctaatt
    24721 catatttttg tttttctaat tttaaatata ccttttgtaa aacctcaaga atatcagaat
    24781 atttaggatc tttacttata gatatatcat tatataattc atgaacaatt tgcttagcat
    24841 tttttttcat tttagcactt ccctggaatt gctccaccta aaaaaccacc tatagacatt
    24901 cctgcaatac aagtagttgc cttggcccaa tcgaccgtac atttattttt agtgcaatac
    24961 actccatttc cataatattt tccactatga gtggtacccc catagataag ttgtgtctct
    25021 ttaatagaca aaatttttaa atgtttcata atctaatcac ccctaaatta atgtttttag
    25081 actattattc taacattcat taaatttcaa aaaacaattc cttcttgaaa cgtagcaaaa
    25141 taattcctga ataagaattt aatcactttt aagtatataa actatgtata ttctttaata
    25201 ttttttgaga atgcacttcg tacataataa actttaatca cattagtctt tcatacctac
    25261 gatcgatctc tttgactcgc acccataaat tcataatagt ttgtcggcgt ctttggacgt
    25321 ttcgaagatg agctacgcat tctctttttt tatagacaaa aaagatagag acgaacatgg
    25381 agcttccaaa tttggatatt tgatccaatt ttggaagctc catttatttc gtgtctgtct
    25441 ttttattttt tccagctttc gactaattct tggttctctt tgatccagtc ttttgctgct
    25501 tgctgtggat cttttccatt gttgatttcc aacataactt tttccatatc tttttctgac
    25561 caatggaaat tgtctaatac tttgtaagct tctggctggt cttctttcaa tccttttcga
    25621 accatcgtat ggatctgctc ttcgcttccc attccgtttt caggatcttc taagtatttc
    25681 agatcatatt tggcaaacat ccaatgaggt gtccatcctg taactacaat tggttcgtgt
    25741 tttttgatcg cttgacctag tgcaacggtc attgctcctg aagaagatgt ctctactttc
    25801 cagtctttca agttgtcata tttttggatc gtgttttcag cagccgtaac tacaccagct
    25861 cctggctcga ttcctatgat tttcttacct gcctgatcgg ttaactcatc gatcgaattt
    25921 acatccatgt aggctggcac tgctaaacca acttttgctc ctgtcaaatt ggcacctagg
    25981 tcttcgactt gatctttata ttgtgcatat tgtgaaccat gagttttagg tagccaagct
    26041 gaaaccatgg catctgactc gccatttgaa acagatttcc acatgattga attatctaat
    26101 ggcgtcatcg ttacatcata gcccatttgt ttcaatactt caccgactac atttgttgaa
    26161 gcaacttctg tatcccattc aacataagat aagttgatac gttttgtttc tttggcagat
    26221 gaaaaactcc ctataccaat cgcacctaag atcactacta ctacagcacc aatgatcagt
    26281 ccttgacgtt ttttactttt ctgtgttgtt gctcctgcag cttttttatt gtttggctgg
    26341 ttcaaatgct gtgtaaaacg gtcaatgatg attgctaaga taactaatgc aaccccgttg
    26401 acaaatccat tcccgacttg tgctctttgc aatgctgata atacgccgcg tcctaagccg
    26461 ggtgcaccga tcatagaggc aataacgacc attgaaagtg acagcattgt tgtttgattg
    26521 atccctgcca tgatcgtact tttagctaaa ggcaattcta gtttgaatag tttttgacga
    26581 cttgtgctcc cgaatgaatc agaagcttct actaattctt taggaacttg tcgaatccct
    26641 aaattcgtaa aacgaacggt tggtggcaga gcaaagatga ctgaggcaaa tacccctgga
    26701 accatcccga taccgaaaaa tgcaactgct ggaatcaaat aaacgaatcc tggcattgtc
    26761 tgcataaagt caaggatcgg tttgataata ctttgggctt tactgctttt tgccatcaag
    26821 atccctaatg gtaccccaat gatgatcgag atcacactag ataaaagaac aagtgtgaca
    26881 gtattcatca aatcattcca tagaccttgg ttataaataa accatagacc gattaatgtg
    26941 aacaacgtaa gtcctggacg tttcttagaa ataaagaaag ctgctaccgt caataacaag
    27001 ataaacaaag gagctggaat cactaacagt aaatttgtaa tccccgacat cactgcctgt
    27061 ccaatcgttt gtaaaaatga aaataggcca gaaaaagttg tcgtaaacca ttctgtgata
    27121 ttttctaccc agtttgccac tggtaattga tagttcaata gattattcat gttcactcac
    27181 ctcgcttgtt tctgctaatg cttcaatcac actacctcgg atgacgacac cttttaattt
    27241 tccatcctct acaactgcaa gtggagtcgg tgagtcataa ataatattga aaatatcact
    27301 taccaccatg tctttcccaa tcaccgtcac attttcatct aggaagtcga tcaatggacg
    27361 tttttgcttc ctagcttcta acgcttgatc tgcagtgatg atccctttca ggtgtctctt
    27421 tctgtcaaca gccatcagca tgctgacttc ttcattacgc atccttgtca atgcaacgtt
    27481 tggtccatca gattcgatat tcgtcgtcaa tgcaggtacc atgatgtttt gagccgtaag
    27541 cactttggaa cgatcgactt cttccacaaa ttcacgtaca taatcatttg ctggattggt
    27601 caatatttct tcacctgttc cgatctgcat gatttcgccg tctttcatca aggcgattct
    27661 gtccccaatc cgtaaagctt cattcaaatc atgggtaatg aaaataatcg ttttttgaac
    27721 attggcttgc aggtccagta attcgtcttg catttctcgc cggatcagcg gatcaagagc
    27781 cgagaacgct tcgtccatca gcaagatctc aggatcattt gctaaagctc tggctaggcc
    27841 aacccgttgt tgcatcccac cagataactg actaggatat tggtctttaa atgaaagcaa
    27901 actagaattt tctaatgctt tttctgcttt ttcttgtcgt tcttctttag gtacaccacg
    27961 gacttctaac ccgtattctg tattttccaa gatcgttcga tgtggaaaca gaccgaagtt
    28021 ttggaaaacc atattgattt tatgacgacg gacttctcgc aattcttctt tgcttaactt
    28081 cgatacatct tctccatcaa tatagatact gcccgaagtt ggctcaatca gacgattcaa
    28141 tagacggatc aatgtggatt tcccactccc ggaaagcccc atgatcacga agatttctcc
    28201 ttcttttacg tcaaaattca cgtcatacac accaaccgtt gcaccggttt tctttaaaat
    28261 ctccgttttc ggctggtgat cattcatcat atctaaagcg gcttgtgtct ttttaccaaa
    28321 tatctttgtt aaatgtttta cttctacttt taccaaacaa attctccttt tttatgtaaa
    28381 ttcatttttc tttctgaaaa aagtgaccac actatgttaa catcatgtag tcactttgtc
    28441 aaaaatgaaa gaaatttgct tgtccaaact gaaaaaaact tggctaaatc tttgtaaata
    28501 aaaggtttag ccaagttaat atttttttaa tatttcacac aatcattctg caagctgatg
    28561 ctccgggtaa aaaaagtttg tcatacgctg tagtgtatat tcatttccaa taaaatgaac
    28621 gatgtcccct gccgtaaatt tagcataggg gccaggtgaa acaagcagtt cttcattatg
    28681 agaaattgcg ataactgtgg cgccagtcgc ctgccagata ttcaactcgc taattgaacg
    28741 gtccagatgc attgcttttt ctgataaaga taattcaaac ggaagtaaag gattcatctt
    28801 atgtattcgc ttcgtttgat tgaccagctg atccaataat tgagaaaaat gattcagctc
    28861 atcttgttgc ttctccacac ttgccatgat ttctgctttt gtatcttgga tggattgtac
    28921 atcttgatat tgcaatagga aatcttttgc tttttccttc gaagcaacaa atgccccact
    28981 tccatgccgt acttccatga ttccaagatc taccagcaca ttgatagcct tgcgggtagt
    29041 ctcaggagaa gcattgtacg tactggcaag tgttgagcgg gcatggatct tctcacccac
    29101 tttatatcgg ttttcaacga tacgttcggc taaatcaaca gcaatctgct ggtagcgcgg
    29161 gcggacgatt tttttctttc cagacatttt ctttcctctt tcttttttta ctttccctca
    29221 tcttactatg ctctagcaaa ataagcaaaa aaggggagaa tagcctcttg caacgactga
    29281 tcatcgcttg atctgttcct tttttactgg gcaagctgtt tgacagtcat cacaattctt
    29341 accggatttt aaacgagtat agacaattgc gcctgcactt ccaaagatta acacacttaa
    29401 taagaatgtc gccatcctat tcctctcctt ctaatgacaa tatagtataa aactggttct
    29461 tggattttgg ctgacggaac aaaacataaa cgagtcctat catcagtaaa atagcaagat
    29521 acgtccctaa cgctacctgt ccaccctcca ataagtgtcc caactgataa atcacaaaac
    29581 taactaaata agctaaaccg cattgatagc ctatggcgat ccaagtccat ttcttggcat
    29641 tcatttcccg atggatagcc ccaattgccg caaaacaagg cgcacaaagt aaattgaagg
    29701 ctaacaatga ataagctgct gcgggagtat atgtgtgttg tagcacttgc cagatttctc
    29761 tgccattttc ggatacttcc gcatgaccaa acaaaatacc aaatgtgcca ataatatttt
    29821 ctttagcgac caatcctgta atcgctgcga ctgttccttg ccagtttccc caaccaagcg
    29881 gctgaaaaac aactgccagg attcgcccga aaaaggctaa gatactttgg tcttcagaaa
    29941 caggttgagc ataaaaatta taagaagagc tgaaccagat cacgatacta gaaacaaaga
    30001 taatcgttcc tgctttttta acaaaagact tgctgcggtc ataggtttgt cttaggaccg
    30061 ctgaccattg aggaaaatga tatgcgggca attccatgat aaaaggagct gtatctccag
    30121 caaacaaacg tgtttttttc aagctgattc cagagaaaat aattgcagtc ataccaagaa
    30181 aataggcaga aggagctacc caagattgat gaggaaaaaa ggcccctgct actaaggcaa
    30241 taatcggcaa ctttgcagaa caaggcatga aggttgtgac catgatcgtc aaacgacgat
    30301 cttgctcgtt ttcaatcgtg cgactggcca tgacgcctgg cactccacat cctgtagcaa
    30361 tcagcatagg aatgaaggat tttcctgaaa gaccgaattt cctgaaaagt cgatccatga
    30421 caaaagcgat cctcgccata tatccgcagt cttccagaaa gctcaagcat aaaaacaata
    30481 taatcaattg cggtagaaat cctaacactg ctcccacgcc tgcgatgatg ccgttcaaga
    30541 tcagctcctg catccatccc gctacttgcc attcagctaa caatctgcca acatgttctg
    30601 gtaaccatgt accaaacaat gtgtcattga tccaatctgt ccccattgtt cctactgttt
    30661 gaatagccag ataatagatc agccacatca caaatgcgaa gatcggcaag gctaaccaac
    30721 gattcgttgc aatctgatcg attttgtcac tcatcgataa ttggaaagaa tcatttgaca
    30781 caacacagag tgtacatagt tgggtaataa attcataacg ttcattgacc agaatcgtct
    30841 cactatcgtc gtccaatagt ttctctgtta actggatcag ttgctcgatc tctttttgct
    30901 gagaaactgc tatctcgtaa tcctctctta ccttctgatc tcgttcaaaa tatttcattg
    30961 cataccagcg tttcttgccg ctttgttctc ctagtacatc ttcaatttca tgtaaagctg
    31021 cttctaaacg tggatcatat gtacagggaa caggaataga aggccgcttt tttgcagact
    31081 cctgaatctt ttcgattagt ttttcgattc cttgcttttt caatacgctg attggtaaaa
    31141 ctggtacacc aagaccatag gaaagctttt ctagattgat tttttttcct tcttttttga
    31201 tgacatccat catattcaga ccaatgatca taggaatgtc taaatccaat aactgcgtag
    31261 ttaaataaag atttcgttct aaattggtag catcaataat gttgatgatc agttcaggct
    31321 gttcctgaac caaataatct cttgcaatca cttcttctgg tgtataagga gacaaagaat
    31381 agatgccggg taggtcctga atatgaatgt tcggattttt tttcaacgat ccttcttttt
    31441 tttctactgt tacgcccggc caattcccta catattgatt cgaaccagtc aagagattga
    31501 acaagctagt tttcccgctg tttggatttc cgactaacgc gatattcatt ctttttcctc
    31561 cctttgtatc aagattagtt cggcctctga ctttcgtaac gtcagttcat accctcgcac
    31621 tgtcagttcg attggatctc ccagaggggc tagttttcgg ataactattt ttacatttcg
    31681 cgtcaatccc atatccatta accgtcgctt cactgcgcct tgtccgtgga ttgctacgac
    31741 gatcccagtc tctcctgctt ttaattgatc aagagaagtc cagctttcag aggaagcagt
    31801 ctttttattg acaaagattt gacctagtat ttcccgactt actgccactc gatgactttt
    31861 taccagtaaa atggcattgt tgcctgataa attgacgacg acgattttac ttccggcaac
    31921 gatcccgata ttttgcaaat ggcgttttgt tttttcttct gtttcgattc gttcgacttg
    31981 ataaacgaaa ttctgctttg cctgcgctaa ggtctgcata ttgattcctc tcttgtgaaa
    32041 taaatcatgt attaaaatca ttcattatat gttctaattt tcttacgtgt tacgcaaata
    32101 aatgagaatc attctcacat agaatactct cggtaattga gaatgtcaat tatacttgtg
    32161 atattatgag cgaatcttta gtattgatag ataaaaatga gaaaaaaata tttcttcata
    32221 gttttccaca attttttctc tattaaattt gctattttcc cacacgatac ttgttttcag
    32281 ctcttttttc aaaaacacaa aacttagtat tccacagttt ccacaacaca atatgtagtg
    32341 tttgttgttt gactttttta ctaagagttt tatactatct attatagata ataagaatgt
    32401 gttagaggag gcactcacca tgaacgtaaa aatcttttct aaaaataatt gtatgcaatg
    32461 taagatggtc aaacggtttt taacagaaaa tcaaattgct tttgaagaag tcaatatcga
    32521 tgaacagcct gaagcagtag actggttgaa agcacaagga ttccaaagtg ttcctgtcat
    32581 tacttctgat gcagaaacag ttatcggatt ccgtcctgat cagttgcgta aacttgccag
    32641 ctaacatgac taaaagaatc aaaacgtgat acatggattt gaagggcttg agacagcacc
    32701 agtttttgtc gcaaacttcc aaatcctttt ttaaagctta aaaacaatgc aatgatttgc
    32761 aatcaagcat catcaaatac gaaatgaagg ttgggcgtac gtatgagtct taaaaattta
    32821 caagatgtca gttatttcaa gctgaataat gaaatcaatc ggccagtcaa tggtcaaatc
    32881 cctttgaata aggataaaga agctttagtt gccttttttg aggaaaatgt caaaccaaat
    32941 acgatgactt ttctatctat tatggaaaaa atcaattact tgatcgatca agaatatata
    33001 gaagcagaat tcattcaatt gtattcacca tcatttattg aaaagctata tcaatttttg
    33061 gacgagcaac atttttcttt caaatctttt atggctgctt acaaatttta ttctcaatat
    33121 gcgttgaaaa ccaacgacgg ttccgcttat ctggaaactt atgaagatcg agtagccttc
    33181 aatgcgcttt actttgcgaa cggggatgaa gaattagcac ttgctcttgc agacgaaatg
    33241 atccatcaac gatatcagcc agctacacct tctttcttga atgctggacg taaacgtcgg
    33301 ggcgaattgg tgtcttgttt cttgactcaa gtcactgacg atatgaactc tatcgggcgc
    33361 tcaatcaact ctgctttgca attgtcccgt attggtggcg gcgtagggat tactttatca
    33421 aatcttcgtg aagccggcgc tcctatcaaa ggatatgagg gtgctgcaag tggtgtcgtt
    33481 ccagtcatga aattattcga agatagtttc agctattcta atcaattagg tcagcgtcaa
    33541 ggagctggcg tggtttattt gaacgttttc catccagaca ttattgcttt cctttcagca
    33601 aaaaaagaaa atgcagatga aaagattcgc gtaaaaactc tttctcttgg cgtgatcgta
    33661 cctgataaat tttatgaatt gacacgtaaa aacgaagata tgtatttatt tagtccatat
    33721 agtgtcgaaa aagaatatgg tgtcccattc tcttatgtaa atattacagc tgagtatgat
    33781 catctagttg caaatccaaa cattcgcaaa caaaaaatca aagcgcgtga tcttgaaaat
    33841 gaaatctcaa aattacaaca agaatctggc tatccttacg taatcaatat tgatacagcg
    33901 aaccgcgaga atccaatcga tggcaagatc atcatgagta atttatgttc agagatttta
    33961 caagttcaaa cgccttctgt gattaacggc aaacaggaat atgaagtatt aggaacggat
    34021 atctcatgta acttaggctc gacaaatatc gtgaatttga tgcaaagccc taactttggt
    34081 caatctgtgc gtacgatgac tcgtgcattg acatttatta cagatgcatc tgatatcgat
    34141 gtcgtaccac cgatccaaaa cggaaataag ctgaatcata cgattggatt aggtgccatg
    34201 ggcttacaca cttatcttgc aaaagaacaa atggaatatg gctcagagga ttcattagac
    34261 tttacaaata tttacttcat gctgttgaat tattggacac ttgttgaaag caacaatatc
    34321 gctcgtgaaa gaaaacaagt tttccataat tttgaaaaat cagcttatgc tgacggcact
    34381 tatttcgaaa aatacgtaac tggagaattc cagccaaaat cagaaaaagt caaagcattg
    34441 tttgaaggca tttttatccc aactgctgaa gattggaatg ctttgaaaca agcagtaatg
    34501 aaagatggac tgtatcatca aaatcgcttg gcagtagcac caaatggctc aatttcatat
    34561 atcaacgata cgagtgcaag tattcatcct atcactcgca tgatcgaaga acgccaagag
    34621 aagaaaatcg gtaaaattta ttacccagcg ccttatctat ccaatgagac gattccgtat
    34681 tacacttctg cttatgatat ggacatgcgt aaagtaatcg atgtttatgc aatggcacaa
    34741 caacacgtcg atcaaggcat gagtttgact ttattcatgc gttctgaaat cccagaaggc
    34801 atttatgaat ggaagacaac aacgaagcaa acgacacgtg atttgaatat tttaagacat
    34861 tacgctttcc acaaaggaat caaatccatt tattacgtac gtacctttac tgatgatgca
    34921 gaagaaatcg gaagcaatca atgtgaaagc tgcgtgatct aatatcatag atagattcgc
    34981 ttattcatat tttaattaaa ggagcattct catgtcagaa acatattatg aagcaataaa
    35041 ctggaatgaa attgaagata tcattgataa atccacttgg gagaagctga cagagcaatt
    35101 ttggctagat acacgtatcc cactttcaaa tgacctagat gattggcgta cattgtctca
    35161 attggaaaaa gatacagtag gacatgtatt tggcggtttg acactgctag atactgtcca
    35221 atctgaaagt ggcatggatc agttgcgtaa agatgtccgc actccccatg aagaagccgt
    35281 tttgaacaat attcaattca tggaatccgt tcatgccaaa agttattctt ctatttttag
    35341 tacactgaat acgaaaaaag aaatcgaaga aatttttgac tggacaaata cgaatcctta
    35401 tctgcaaaaa aaagctgagc gtatcaatga aatctacaaa cacggtacac cgctagaaaa
    35461 gaaaattgcc agcgtctttt tagaaacatt cttgttctat tcaggttttt atactcctct
    35521 ttattattta ggaaacaaca aattggctaa cgtagcagag atcatcaaac taatcatccg
    35581 agatgaatct gtacatggaa cctacatcgg ttacaaattc caattaggat tcaacgagtt
    35641 acctgaagca gaacaagaaa cgttaaaaga ctggatgtac aatcttcttt atgagcttta
    35701 cgaaaacgaa gaacgttata cagaagaatt atacgatcca atcggctgga cagaagaagt
    35761 caagacattc ctacgctata atgccaacaa agcattgatg aacctaggga tggatccact
    35821 ctttccagat actgccaatg atgtcaaccc aatcgtaatg aacgggattt caacaggcac
    35881 aagcaaccat gacttcttct cacaagtcgg aaacggctat ttgttaggtc atgtagaagc
    35941 gatgaaagac gacgattatt tgattggatt ggaataagga tttattttaa ttcaaaaatt
    36001 tttcgaaaaa taaaaagagt ttagcgtaca gatattttaa atgtacactg aactcttttt
    36061 tatgcttatt cacttgtttc ttccagcact tttggactgt ctaacttttc cgaaacatgt
    36121 tccattcttc tcaataaata gattttccgg atatttaata ttatcgtctt aatcactgca
    36181 tagacaggta tgcaaatcag catgcctaat attcctgcga cacttcctgc tccaatcaat
    36241 accaagatga tcgtcaaagg atggatattc attgatttcc caaataacaa cggcttgatc
    36301 aaatttccat ctaattgttg gatcactaaa atcgacaacg ccatatacaa agcttgaaat
    36361 ggagagataa acaaaccgac aatgattgct ggtaccgctc caataaaagg gccgacatac
    36421 gggataatat tcgtgattcc gcaaatgacc gcaagcaaca agctataagg ctgatcgaat
    36481 attctcattg ccaaaaagct cattacacca ataatcaaag catctaagat cgtactgctg
    36541 atataggcag ataatgtttc gtttaattct tttaccgttt ggcgtaactc tttacgaatc
    36601 gctttcggaa agaagtgaga caacgcatca ataaatttgt gcccatcctt gaacataaat
    36661 agcaaaataa atggaacggt aaataacaaa ataaaaaatt gcatcataaa tgaaatgatt
    36721 tttgagacac ttgcagataa actgactaat atgatattga acaaattact aagagataaa
    36781 tttgctgatg ctaattgttc ttccaaattg aaatttttaa actcttcccg ctgcgccaat
    36841 tcatttaacc atttgcttgt ttcatctgca tacattggca agctctgggt caattgaatt
    36901 gtctgttcca ttaactgagg cactacattc atgacagtta aaacaactaa aatgattacg
    36961 accaaaaacg tcaataaaaa accgaacact ctcgggatcc gatgcttttc gagaaaaaca
    37021 acgattggat cgaacatata atagataaaa ccagcaacaa gcaatggtaa aaaaactgcc
    37081 gaaagcattt tcaatattgg actaaaaata ttcggcattt gtaaaataaa gtacacgccg
    37141 atgatcgtga gtactagctc cactgtccag aaaaataatt ttgattgttt aaaacgtgat
    37201 tgcatacatc tcctccaagg tcctttgata cttctattct atcatttaac aaagagttac
    37261 gcgctgagat tttcatttgc ttaaaaaaaa caaaaaaaat aaacatattt taatgagtag
    37321 acgagtactt aaacaaaaac acggtttgga gtagtgacaa aaattatact gcagtccctt
    37381 tttccaaata aacggtgttc aaaagcttgc atcttcgtaa taagcccagc caaacgaaaa
    37441 atataaggaa ctatttttat ttggctgggc ttattacttg atgtaggaca tctattttac
    37501 aacctcagat catttattgc gcaatactga ctaaatgcaa ctttgtgata tttttgtgta
    37561 cggacaactc ctcgatcaca tcggcataag tgagcccttt tggaagatca atcgtataga
    37621 tatttttgta cactcggtag tcatcaacga attttacgtc aaaattcaca tcttcgatta
    37681 cgatattttt ctcttcaaaa taatcggtaa gaaaatcttt ggtttctttt ctatggataa
    37741 attggatttc taacttttta gtcgtaggta catggatcac gcgtttcact actgtgagtg
    37801 caatagcaat cccgataaaa ctgatgatcg caatggaata gtaacccatg ccgatggcga
    37861 tccctaatcc agcaattgcc cataaagaag cggcagtcgt aagtcccgtc accgattgtt
    37921 tcgtgacgat gatcgttccc gcgcctaaga aaccgacacc actcaccact tgagcaatca
    37981 gccttgcttc atctgaacga atcgttccag caagctgtgg atactctaaa gcatctctta
    38041 atgcaccact agcgatctca acttggatca atgcaatgat acatgctccc atacaaacta
    38101 aaatatgcgt acgcatacct gctggacgat ttttatattg tcgttcaaaa ccgattgctc
    38161 cgccaaatag catagcgatc cctaaacgta aaataatctc tggaattgtc aataccatat
    38221 cattcatcta aacaccctcc agtccaatat atcatgtctg aaaggagcag acaaaaaaag
    38281 tgcaattttt acctcttacg aaaaaaggac tgtgacaaaa tttttgtcat agtccttttt
    38341 atgaataaac ggtgttcaat cagctgaccc tcggtattac tcaacaaacg gcaaaatatg
    38401 gggagctatt tttcctttgt cttctctaat actcaggtca aaacgctgat ttcacaacct
    38461 ctttagccta ctattgaaaa ttacaactta cttgctgctt cttcatcgat gatcacaaca
    38521 acattgtcgt gattttgcaa tacacttgct ggcaaatgat tcgttacagg tccttcaatc
    38581 atccctttga ttgcatcagc tttgctttcg ccaaatgcca tcaagacgat ttctttactt
    38641 ttcataattg aaccgattcc cattgaaaca gcttttgttg gtacatcttc tgctttatcg
    38701 aagaatcgtt tgtttgcatt gattgttgat tctgttaagt caactactga agtcgttccg
    38761 tcaaatgaag caccaggttc attgaaaccg atatgtccat tttgcccgat tcctaagatt
    38821 tggatatcga ttggatgtgc atcgatgatt tgatcatact ttttgcatgc tgcttccaga
    38881 tcttctgctt ttccatctgg tacaaacgtt tctttgaatg gttttttatc aaataattgg
    38941 acatccatga aatgacggta gctttgttca tctgaaccgc ctagtccaac gtactcatct
    39001 aagtttacag aagtcatttc actgaaatcc aaatcgcttg aagtcatttc tttatataaa
    39061 gtaactggtg tgcttcctgt tgccaatcct aatacttttg cacctttgtt cataccttct
    39121 ttgatgattt caaatgcttt ttttccgcct tcttcagcgt tttttacacg aatgatttcc
    39181 atagtgattg ctcctttata ttttggtata gcccaattat agcattcttt ttttcttttt
    39241 acaataatta gtatagacca aattgcattt ttttcatttt cttgacaata aataggaatc
    39301 cgtgttaggt ttcataagat ggttcaatca aacaatccat gttgcatgaa aaccaagcaa
    39361 gtgattcact gtggacgctt tatgtctgca gtttttttat gaaaaaggag ttattatgag
    39421 tatactgaca ttaaacaaca ttacccagca atttggcgac aaaatcctct atgaaggtgt
    39481 cgatctgcaa ttaaatgctg gcgaacatct tgggctgatt ggacaaaacg gagccggtaa
    39541 aagtacattg attaaaatca tcactggtga gatcttacca gatgacggac agatccattg
    39601 gcaaaaaaat attcacaaag gttacctcga tcaatatgtg gaagtcgatg aaacattaac
    39661 aatcgaagaa tttctaaaaa ctgcgtacgc aaaagaatac gaaaaggaag aaaaaattgc
    39721 ttttctttac caaacatata gcgagacctt cgatgattcc ttgctggaaa aagctgggaa
    39781 actccaaacg gaattagacc aaggagtgtt ttatcaaatc gacaccttag ttgctgagat
    39841 gagcagcggg ttggggatcg atgtcttagg tttagattca ctgttgaaaa atctaagtgg
    39901 tggacaacgt tcaaaggtga ttttagcaaa actactttta gaaaacccag atgttctgat
    39961 cttagatgaa ccaaccaatc acttagatga tcagcatatc caatggctga cgcagtttct
    40021 tcaggatttt gacggtgcgt atatcgtgat ttcccatgac caagaatttc ttgatcagat
    40081 caccacccat atcgcagaca tcgagtttgg aaagattact aagtatactg gccatctaaa
    40141 acaagcattg aaacaaaagg aacaaaatcg cgaaagctat ttgcgccaat atcatgctca
    40201 acaaaaacaa atcgaaaaga ccgaagctta tattcgaaaa tacaaagccg gttcccgatc
    40261 aacgatggca aaaagccgac aaaaacaatt agataaaatc gaacggctga cgcctccagc
    40321 ttcagcaagt aaagctgtct ttgattttcc attctcgcct attgtcacga cattagcagt
    40381 ggaaacaact gatttagtca tcggatatga tcgaccgcta cttgcaccca tcaatttgac
    40441 catccgcttt ggtgaaaata ttgccattcg aggcttcaac gggattggaa aatctacttt
    40501 attaaaaaca ctgatcggtg agattgaaaa aataagtggc gatttccact tcccagataa
    40561 cacaaaaatc aattactttt cacaagatct gtactgggaa aatccattag aaacaccact
    40621 acaatattta agcagtcaat ttccaaaagc gactatcaaa gaattacgtc gccaactagc
    40681 taaagcaggg ttagttaatc aattagcaag tgaacctctc actacattaa gtggtgggga
    40741 acaaactaag gtgaaacttg cacagttgac aatgaaccaa ggtaatttac tgattctcga
    40801 tgaaccgacg aaccatatcg atcaagaaac gaaagaaagc ttacaagacg ggatacagaa
    40861 atttccagga acagtaatca tcgtctctca tgaacaagaa ttttatcaag atcttgtgca
    40921 acgagtcatt gagattgaac caaaataaac gtttgattga atagttgaaa aaaaggagct
    40981 gtgacaaaag ttttgtcaca actccttctt ctgaataaat ggtggccaat tagctgacct
    41041 tcggtattag ctcaaaaaac ggcaaaatat gaggagctat ttttatttgg ctattcttat
    41101 tacttgatgc agaacagctt ttcacaacct cttttcgtct attttttatt ttcgagattt
    41161 ctctttcctt taaaaacaac tgtttgaaag aagaacgcac atccttgaaa aacaagcccg
    41221 ctaaccgtta cacctaacca gccatactgc tgccacattg tcgtccctag caatgaacca
    41281 gccgcacctc caataaagta cataaacata aatacagtat tatttcggtt gcttgctgct
    41341 tcacctagcc cttgtactcg tgtttgattg gcgacttgac caaattgatt cccgacgtct
    41401 aataaaataa tagctaaaag caaaatggcc aaatggcttc cgccaaccaa taaagcaata
    41461 aagcttattg tttgcataac aagtcccata tacacgattt ttctttcaga ataagaatct
    41521 gccagtcgtc ccacgatagg tgcagcaact gctccagaca aaccaaaaat cgctaatatc
    41581 cctgcttcga atgttcccca attgtaggcg ggactgctga tataaaaaat caacgtagac
    41641 caaaagatcg aaaatgttcc aaacatgaaa aatccactga ctgccgcttc tcttaataga
    41701 cgttgagaag caactaaatg cggcaaactt ttaagtgaat caaggtatga aacagctgta
    41761 ctactttgct ggacagaacg cggcattttc cagtaaagca gaagtgtaag aattccgact
    41821 gcacataaag caaataaata gatcatccgc caagaaaaaa gactggcaac aataccagat
    41881 accgtccgag aaagcaaaat ccccacgagt aaaccgctaa gcaatgtacc catgaccttc
    41941 cctcttgctt ttggtcccgc tagtaccgca ccgtaaggaa tgatgatttg cggcacgatc
    42001 gaaagtaatc ctattaaaaa agaagcgcat gcaaataacg taaacgaagg cgcaaaaaaa
    42061 gcggccaaca gagagacggc agataacgct gccattcgaa tgatcaattt tggacgatcc
    42121 accacgtccc ctaaaggaac taaaaacagt aaccctaacg catagcctaa ttgggtcaac
    42181 atcgtcaata tcccgactgc acttgtgcta acagataaac tagctgctac ttttgttcca
    42241 atcggctgga tgtaatacat attggcaaca acaacgccac aagtgattga taatagtaaa
    42301 ataagcgaag ttgttaaagg ttttttttca ttactcttca ttgatttccc ccatttccta
    42361 tcttagttta caacttatgg aaaagattgg aaatagaaaa atacaactat tcgccacact
    42421 tattatttgt gcttttgttt tccttgtttt ttcttgcgat ctttataaat gaagacaact
    42481 aaccctacta gcacagtaac acttgcaacc aacgtgactg cagttttgtt atatccgtga
    42541 aacagagctt ctccaccaca cgcatacaac acagacgaag ggatgactcc aatcacgatc
    42601 gacaatatga tttgctgtag aggcaatttc atcgcatctg cagcaaaatt gaccatagaa
    42661 gatggaataa ccggtatcat atagcctaac attacaccta tttttggatg tttcatttgt
    42721 cggattgctt gcacccaatg attcgtttcg gttttcttat ctaaaaattt taagcgatgc
    42781 ataaggaaaa ttgcagtgat gttaccaaga gcattaccca aaatgttgat gatcgcacct
    42841 gtcagtggtc caaagctcaa accagcaatg actccaacta ctgaagtagg aatacctgga
    42901 acagcacaca tcaccgctgt caatacgatc aagagtatcg atgcaaaagt cccatgcgaa
    42961 cgaatatgtg cgagtagctc tgccttactc gctctcggat ttaaaaataa ttggatgtct
    43021 gtctgatatt ctaaatacaa ccgatagccc actaccagta tcagaatgat tcccaacgag
    43081 atcaatatca atcggattat tttctttttc atatttcctc ctgaaaaaaa tctatattca
    43141 ttaaataata gtttaacata aaaacaaaaa agcaccgaaa tccaacatag gatctcagtg
    43201 cttttaaata gtaaaaatta tttaacagtt acagatgcgc caacttcttc aagtttagct
    43261 ttcaattctt cagcttcttc tttagatacg ccttctttaa ctggtgcagg agcgccatca
    43321 actacagctt tagcttcttt caagcctaaa ccagttgctt cacgaactgc tttgataact
    43381 ttaacttttt ggtctccagc tgcagttaat tctacagtga attctgtttg ttcttcagca
    43441 gcagcagcgc caccagcagc agctacagct acaggagcag cagcagatac gccaaattct
    43501 tcttcaatag ctttaactag gtcgttaagt tctaggatag ttgcttcttt taactcagca
    43561 acgatgtttt caatgttcaa tgccattata atttcctccg tttaattgtt cttttttatt
    43621 taatgcttta tgcggcaatt aagctgcatc tccatcttct ttgtctgcca ctgctttgac
    43681 agcgtaagcc acgttgcgga ctggcgcttg tagtacagat agcaacatag atagaagtcc
    43741 ttcgcgattt ggcaattttg ccaatgctgt gatttcttcc aatgaagaga ctttaccttc
    43801 gatgataccg cctttgattt ctaatgcttt tgcttcttta gcaaattcgt ccatgatttt
    43861 cgctggtgcg actacatctt cgttactgaa tgcaacagct gtaggtccag tgaatacttc
    43921 gtccatgcct tcaaggccag cttttttagc tgcacgtgaa agaatagaat ttttgataac
    43981 tttcatttct acgttagcat cacgaagttg tttacgtaaa cgtgttactt catcaactgt
    44041 taatccgcgg tagtcaacga ctactactga tgcagctgct gtaaattttt cgcttacttc
    44101 atcaacgatt gctgcttttt ttgcgataat tgcttcactc atttttgagt ttcacctcct
    44161 gaattttgat ggaagagttt tttgcactga aaaggcaagt cacttttata gttactttgc
    44221 tcaaccagta ttattcatca cctattcact tcgttcatag tgattctact cgctttgctc
    44281 gaaaggaaac tcctttcgct ttgctcaacc agtattgttc atcatctctt cacttcgttc
    44341 atagtgattc acaataaaaa actctatgcc accgcagaca tagagggact attgaatata
    44401 ttcaataaac gtcctcggta ggaaattaag gcttgatgcc acctactgtc ttcggtacaa
    44461 gttaattatt aacctcaact agcttagcat gctaaactag ttgagtcaag aattattttt
    44521 cagttggatc aatcaacatt ctaatattta attagaaaga agcttggtca acatggatac
    44581 caggtccaaa tgttgttgtg atcgttacat ttttcatgta ttgaccttta gctgctgatg
    44641 gtttagcttt tagcaataca tcatggattg ctgcaaagtt ttcaactaat ttttcatcgt
    44701 caaatgaaac ttttccgatt ggtacatgga tatttccagc tttgtccaca cggtaagtta
    44761 ctttaccagc tttcacttcg tttactgctt ttgttacgtc cattgtaact gtaccagttt
    44821 tagggtttgg cattaagcct tttggtccta atactcgtcc tagacgacct acagtagcca
    44881 tcatatcagg tgttgcaaca actacatcaa agtcaaacca tccgttttgg attttttgaa
    44941 ccatgtcgtc gtcacctacg aaatctgcac cagctgcttc agcttctttt gctttgtctc
    45001 ctttagcaaa aactaaaaca gtttgtgttt taccagttcc gtttggtaat acaacagcac
    45061 cacggatttg ttggtctgct tttttagggt ctacgttcaa acggtatgca acttcaactg
    45121 ttgcatcaaa ttttgcaatg tttgtttctt ttgctaaagc tactgcttcg gcaacaggat
    45181 aaactttact tgaatcaact ttttttaatg catcttgcat ttttttgctc tttttagcca
    45241 ttttggttcc tccttgattg tggttataac ggttgtacct cccacgtgtt ctatatcttt
    45301 caatatagag ccaactgaga agctgctgtc ttagggtgta tagattattc tacagtgatc
    45361 cccatgcttc gtgcagttcc ttcaaccatg cgcattgctg cttcaacgtt agctgcgttt
    45421 aggtcttcca tttttaattc agcgatttct cttacttgat cgctagaaac tttcgcaact
    45481 ttatttttgt ttggttcgcc tgaacctttt tcgattttag ctgctttttt caatagaaca
    45541 gcagctggcg gtgtttttgt aacgaatgtg aatgaacggt cttcgtatac agaaataaca
    45601 accggaatga tcaaacctgc ttgatcagct gtacgagcgt tgaattcttt tgtgaatccc
    45661 atgatattga tacccgcttg acctagtgca ggacctactg gtggagctgg agttgcttta
    45721 cctgcaggaa tttgcaattt aacgattttt tctactttct ttgccacgag acatacctcc
    45781 ttaagtccgt gatgtggtta attggagatg catatttctc ctcccacgtt ttatctgatc
    45841 tgaaaaaatc cagacaaata atgtgcaaaa caatgcacac tggtacagta tagcaaattt
    45901 atttgttttt tcaagatttt tttctgctat ttttacattt tgcttgaata aacgctaaat
    45961 ttattctaaa aaaacaacaa tttttcgttc tcatttcttc ttttatgtta cacttgcgct
    46021 agcatggttc aacagatgaa agcaaacaat aacacggttt tttagaccct tgtacaaaga
    46081 ttcctacata acaaaatgag gtggagaaaa tgaaagattt aaggtataga agtgtctttg
    46141 atattattgg acctgtgatg attggtccaa gtagctctca cactgccgga gctgctagaa
    46201 tcgggaaaat catacgtagt atatttggcg aacagcctga ttctgtagat atttatctat
    46261 atgaatcatt tgcaaaaacc tatcgggggc acggaacaga tattgcatta gttggcggcc
    46321 tgttagggat ggaacccgat gatgaacgtt tagctgattc tttgaaattg gcatatgaag
    46381 ccggtatgga agtcttgttt gttcctaaga gtgaaaaagc cgaacatcca aactctgtaa
    46441 agatgcttct aaaaaaagga acacgaaagc tttcagtcac tggcatttcg atcggcggtg
    46501 gcaatatcca gatttctgaa ttgaatggat tcaaaatttc tttaagcatg ggtactccta
    46561 ccttgatcgt tgtccaccaa gatgttccag gtatgattgc taaagtgact agtatacttt
    46621 ctgagaccaa tacgaatatc ggcactatga cagtgacacg ggaatcaaaa ggtgaaaatg
    46681 ccattatgat aattgaagta gatgatcctc aagtagaaga aacggtaaaa agactcaaac
    46741 agctgccaaa tatcgacagc gtaaattatt tcgattaagg agctaaaaaa atgtttttat
    46801 cgattgaaga attagtagat caagcaaaag cttatccaag tgtagcagaa ttgatgattg
    46861 cagttgaaat ggaaatgagt ggccgttccc gtagtcacat catcgagatc atggaaaaaa
    46921 acctctcagt aatggaacaa tcaatcaacg agggaaaaga aggtgttacc tccgtcacag
    46981 gaattaccgg tggtgatgca aaaaaattag atgattattt aaatgaggca gactttttaa
    47041 gtggagaaac aatcttaaaa gctgtacgca atgctgtagc tgttaatgaa gtcaatgcaa
    47101 aaatggggtt gatttgtgct acaccgactg ccggaagcgc gggtgttgtt cctggtgtgc
    47161 tgatggctgt ccgagatcgg cttgatttga cacatgaaca gcaattggaa ttcttattta
    47221 ccgctggcgc tttcgggtta gtcatcgcaa acaacgcttc tatcagtggt gcagaagggg
    47281 gatgtcaagc agaagttggt tctgcaagtg caatggcagc agcagctttg gtttgtgcaa
    47341 aaaatgggac tcctcatcaa gcagcacaag cagtagccat tacattgaaa aatatgatgg
    47401 gactgatttg cgatcccgtt gcaggcttag ttgaagtccc gtgtgtcaaa cgtaatgctt
    47461 taggctcttc tcaagctttt atctctgctg atatggcatt agcgggtatc gaaagtgtca
    47521 ttccgccgga tgaagtcgtt gctgcaatgt accaagtcgg acgtcaaatg ccgtcgattt
    47581 tcaaagaaac agcagaaggt ggcttagctg ttacgccaac tgctaaacga cttgcggaag
    47641 agattttaaa taagagggcg tgataaagct ccttaatttc gagtattaag agattagtta
    47701 tcttcataac aaaaaacgaa gagaggacta attgcccttc tcttcgtttt ttattaatcc
    47761 atcaatttcg tattttttac ttcatcgatc gtttttgttc ctgcaagttg catcgtgatc
    47821 gacaattctt tgttcaggtg ttcaaaaaca gatgttactc cttctgcccc acctagattc
    47881 aacccataaa tcactggtcg gccaatcgca actaagtcag caccacttgc cagagctttg
    47941 aagacatgct ctcctcgacg gacaccagag tcgaaaatca ctggtacacg tttgttgact
    48001 acttcggcaa tttttggcaa tacttcaaag gacgcaggac ctccatctag ttgacgtcca
    48061 ccatgattgg atacccagat accatctgcc cctgcagaga tagcgattac tgcatcttct
    48121 ggcgattgta ttccttttac gataactgga agatgggtga tttctttgat tgttttgatg
    48181 tcatctggtg tcaagccttg ttttgcagct gcataaattt ctgcgattcc ttttccttcg
    48241 ccattaccac ttgcactttg ttcgctatac gcagctaagt taggcattgg taatggaaat
    48301 tggaattgat tgatgacgtc ttcttcacgg taaccaccga gcgttgaatc tgccgttaaa
    48361 atgatagctt tagcccctgc ttctactgct ttgttcaaaa tgaactcatt gaatctgtcg
    48421 tctttactca tatataattg gaaaaactgc ggtgcgcctg gcgctgcatc ggctgcgtct
    48481 ttgattgtcg tatttgcata agtgctgatg gaaaagattg atccagcagc agctactcct
    48541 ttagctgtat cagcttcccc tttttcatgt gccaatcctt gggccgctga tggcgcttgg
    48601 ataatcggtg tatctaattc aattccgaaa acagatgtat gcaaatcggc tgagtcgatt
    48661 ccgcgtaata tccgtggcat gattttcttt gtattaaaag aagtcgtatt ttctttcatc
    48721 gtccactcat cttcagaacc accgcgaata tagccaaaag ctcctgcttc catgcgctct
    48781 tttacacgac cttctagtta ggcaatgttt acaatatcga ttggatgttc ttcattactt
    48841 gtatgataag tcatagtaga tccttctttc atcttcttga ttacatataa atcatactaa
    48901 acttacaaaa agtaagcaaa catttactct cagatacttt tatcgctatt ctttccaaat
    48961 aaatcgactt acaagctgat ctacttcttg gttttcatga agcatactat gagaggcatt
    49021 ttcacctgtc actacttttt cctctatttc atttccgcgt tgcttcaaca acgcatagac
    49081 cgctaatgca ctgtttaacg gtactgttcc atcactcaag tctgtttcat ctagttgacc
    49141 agcaatcaag aaaaatcgag tggttatagg aatattaccg atcatttgct ggtaatcttg
    49201 atagcggtta gaaacgacag caggcccctt tgctaactca tctgtcagag actgcgcact
    49261 atcatcgaca aaatcattaa aaggcgcgcc aattgctgtt aatgtctgaa cttgtggcaa
    49321 tgacgtatcc tgtccatacg ttcctaaata gcgtagtgca ctaactcctc ccatggaatg
    49381 ccccactatg ttgactttat ctatgccgta gttttctttc agatacaaaa gacaagtttt
    49441 gatccattct gcttgattcc actcgttatt tttattatct tcaaacaata cttggaccat
    49501 cggattgtct gcttttccag acaaatctcc tgttgcttgt atttgtccat ctgttcctac
    49561 tgttaaaacc aattctttta ctgcttgctg atttttttcc aaacgccgca acatcccttt
    49621 aaaggaattt tctgtcccgc tgtagccgtg gaaaaaaagt gttggaatag tggttttttc
    49681 tatcacttta ctggattctg ccgttttttc tttatcagaa acttcagtag tatttatctt
    49741 cgtcgtctgg caaccactta acgcaaacaa actgataagg actaaagctg ctgcagttgc
    49801 acgtttgcat aaatttttga ttggttctgt catacacctc ttcctttcca tatagaaaaa
    49861 agaaagactt gaaaggccaa tcatatgatc gacatttcaa gtctctttat taatcgattt
    49921 tatctacttg atcgaaatca agttctgtac tggtttcacg tccaaacata tcgatgttga
    49981 ctttcaattt ttctttttct ccgtcaactt ctgttacttg tccttctaat ccagcaaatg
    50041 cgccttcgat gattttcacg acttcgccaa cttctacttc tagatcattt tgtcgcaggc
    50101 tcataccgat agaacgcaag atatgattga cttcttctgg aagtaatggt gctggtttgc
    50161 ttccggctcc gtgtgaacca acgaatcctg tcacaccagg tgtgttgcgg acaacatacc
    50221 atgaagcgtc tgtcatgatc atttcaacaa gtacgtatcc tgggaatgtt ttatgaacga
    50281 tttctttttc tttcccattt ttgacttcag tttctttttc ttcaggaaca acgacacgga
    50341 aaataaagtc ggccattttc atactttgcg cacgagattc gatatttgct tttactttgt
    50401 tttcatatcc tgaatatgta tgcaagacat accagttttt ttcaaaagat tccattgaag
    50461 gctcctcatt tcattgtaaa ataaaaaaac ctcagtacac ccgaagtttt tctttcgctt
    50521 cattatagca ctaaaagtac gttgtggcta gcgagttatt ttaaaatcca gccaaataag
    50581 ctttggatgg ctgtatccat tacgtaaaac atcaatccga aaataataga agtttcgatg
    50641 actactaacg tatctttacg gagttgtttt ctgcttggcc aagttacttg tttgatttca
    50701 tcttttacgc tttttagaaa tttcatgaga caacctccct tgctactgtt tatttcgttt
    50761 ctttatgtaa tgtatattga ttacaatatt tacaaaactt attgatttcc aaacgttcgc
    50821 cgctttttcc ttcactgact gattttgtgt agttgcgaga cccacaaacg gaacaagcga
    50881 gtgctgcttt tttctttgcc atttacttct gcccccttgc tgagaatcag acttatactt
    50941 cataacagta tcacgtaact ttttacttgt caatttgtga aataaactat ctattgtttt
    51001 ggataaaatt atgatatgat taatttgaaa ttaagctaaa atgagacaat tggaggtata
    51061 gcgatgctat taaaaacact tgtatataag aaaaaagatc tgacaaccgt tacagagact
    51121 agtacattag aagaagcatt aaaaatttta gaaacttccg gataccgttg tgtgccgatc
    51181 ttagattctt caggtaatat tttccgtgga aacatttaca aaatgcatat ctatcgtcat
    51241 aaagcaaatg gcggtgatat gacgcttcct gtcactcatc ttttgaaaaa cgctacaaag
    51301 ttcatttacc tggatacttc tttcttcaaa gtattcttta cgatcaaaga gcttccttat
    51361 attgctgtcc ttgacagtga aaatcatttt tatggtattt tgacacatag tacgttgctt
    51421 aatatgctct ctcaatcttg gagcgtagaa caaggaagct atgtactgac aattgcttcc
    51481 acaggaaagc aaggagattt ggctgctatt gcaaaaatca tttcaaaaca cagcagcatt
    51541 gccagctgta ttactcttga tatcgaaaaa gacgaataca ttcgacgtac attgatcacg
    51601 ctaccggcta acactgaagc gaaagtatgt gaaacgatcg tcaaccactt agagaaaaag
    51661 aattataaag tggtagaaat tgaaaatttg caaaaccaag aagcataatc aaaaagcgaa
    51721 aaaagaaaac agctaatctg ctttcttttt tcgcttttta taattagaca cgcttttcaa
    51781 aatcaagcgc gcgatctaaa taatacatca atggtgctga aacagccatg acgataaact
    51841 cacttaatgc aagcgtgcca taggttgtcc aaaatgcttg gccacctgtt ggaactaaca
    51901 tataagcaat cagtcccatg ctgatggtaa agaagatcgt gttcaatact aaacgcatct
    51961 ttacattttt cactttgttt tgcaataaag ctgtcaggcc taaagaaagc aatgtttggc
    52021 cgccaccaaa aaccacatcc atgataccaa aaccaaagaa ggcattatag acgatgaccc
    52081 cgcctaaaac tccccaaagc aatttacggt taaagacaac taaatgattc aaactttctg
    52141 aaatacgaaa ctggatcggc cctgaggata caggcgcaac taaaatagtt aacgctagat
    52201 aaagagccat gatgatgcca tttacaacga ttacggataa ccgttgtctg cttttcgttt
    52261 tttgcatttt ctctcctctt ttctcctagt ttttttaacg cgggatggtt gatgaaccgc
    52321 ggttatgtga aacaaacaat aattataaca gacttttcat ttatttcaat ccgtcttatc
    52381 tgcttttaaa aaagcaaaag cttaaacaat gtaaacgttt gctaaaaatc gtgggatatg
    52441 gtataaagta agtgtaaggg gtcataagaa ttcccagtaa agcagacgaa gtaggatctg
    52501 caagaacaga attgttgtga aacttaaata aataaaaaag gatgtgggaa tttgagcaac
    52561 ctcttactag agaacggtct agcaagcagc tgaagatcta agtggacatg ccgaaccttg
    52621 gaacttctcc ttacgtaagt aatggatcat gcgcttgcta ggct
//
LOCUS       DADGHT010000006        51594 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.006, whole genome shotgun sequence.
ACCESSION   DADGHT010000006 DADGHT010000000
VERSION     DADGHT010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.006"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(22..1722)
                     /locus_tag="JX887_000305"
     CDS             complement(22..1722)
                     /locus_tag="JX887_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256321.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            2229..3389
                     /locus_tag="JX887_000306"
     CDS             2229..3389
                     /locus_tag="JX887_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAX1256322.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            3405..3848
                     /locus_tag="JX887_000307"
     CDS             3405..3848
                     /locus_tag="JX887_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1256323.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(4331..4861)
                     /locus_tag="JX887_000308"
     CDS             complement(4331..4861)
                     /locus_tag="JX887_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAX1256324.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            4966..5517
                     /locus_tag="JX887_000309"
     CDS             4966..5517
                     /locus_tag="JX887_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAX1256325.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(5670..6143)
                     /locus_tag="JX887_000310"
     CDS             complement(5670..6143)
                     /locus_tag="JX887_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAX1256326.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            6281..7753
                     /locus_tag="JX887_000311"
     CDS             6281..7753
                     /locus_tag="JX887_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAX1256327.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            7750..8460
                     /locus_tag="JX887_000312"
     CDS             7750..8460
                     /locus_tag="JX887_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAX1256328.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            8812..9096
                     /locus_tag="JX887_000313"
     CDS             8812..9096
                     /locus_tag="JX887_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAX1256329.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(9413..9796)
                     /locus_tag="JX887_000314"
     CDS             complement(9413..9796)
                     /locus_tag="JX887_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAX1256330.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(9798..10382)
                     /locus_tag="JX887_000315"
     CDS             complement(9798..10382)
                     /locus_tag="JX887_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAX1256331.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(10429..11904)
                     /locus_tag="JX887_000316"
     CDS             complement(10429..11904)
                     /locus_tag="JX887_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAX1256332.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            12085..12396
                     /locus_tag="JX887_000317"
     CDS             12085..12396
                     /locus_tag="JX887_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256333.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(12511..14847)
                     /locus_tag="JX887_000318"
     CDS             complement(12511..14847)
                     /locus_tag="JX887_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1256334.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            14989..15657
                     /locus_tag="JX887_000319"
     CDS             14989..15657
                     /locus_tag="JX887_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1256335.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            15660..16703
                     /locus_tag="JX887_000320"
     CDS             15660..16703
                     /locus_tag="JX887_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1256336.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(16940..17821)
                     /locus_tag="JX887_000321"
     CDS             complement(16940..17821)
                     /locus_tag="JX887_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1256337.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            17980..18708
                     /locus_tag="JX887_000322"
     CDS             17980..18708
                     /locus_tag="JX887_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAX1256338.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            18864..19181
                     /locus_tag="JX887_000323"
     CDS             18864..19181
                     /locus_tag="JX887_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAX1256339.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            19174..19782
                     /locus_tag="JX887_000324"
     CDS             19174..19782
                     /locus_tag="JX887_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAX1256340.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            19798..20628
                     /locus_tag="JX887_000325"
     CDS             19798..20628
                     /locus_tag="JX887_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAX1256341.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            20766..21254
                     /locus_tag="JX887_000326"
     CDS             20766..21254
                     /locus_tag="JX887_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAX1256342.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            21305..22177
                     /locus_tag="JX887_000327"
     CDS             21305..22177
                     /locus_tag="JX887_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAX1256343.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            22353..22715
                     /locus_tag="JX887_000328"
     CDS             22353..22715
                     /locus_tag="JX887_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAX1256344.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            22724..23476
                     /locus_tag="JX887_000329"
     CDS             22724..23476
                     /locus_tag="JX887_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256345.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            23490..25292
                     /locus_tag="JX887_000330"
     CDS             23490..25292
                     /locus_tag="JX887_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1256346.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            25569..26609
                     /locus_tag="JX887_000331"
     CDS             25569..26609
                     /locus_tag="JX887_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAX1256347.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(26661..28805)
                     /locus_tag="JX887_000332"
     CDS             complement(26661..28805)
                     /locus_tag="JX887_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1256348.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(29162..30535)
                     /locus_tag="JX887_000333"
     CDS             complement(29162..30535)
                     /locus_tag="JX887_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1256349.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(30535..30930)
                     /gene="rbsD"
                     /locus_tag="JX887_000334"
     CDS             complement(30535..30930)
                     /gene="rbsD"
                     /locus_tag="JX887_000334"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAX1256350.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(30958..31875)
                     /gene="rbsK"
                     /locus_tag="JX887_000335"
     CDS             complement(30958..31875)
                     /gene="rbsK"
                     /locus_tag="JX887_000335"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAX1256351.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(31983..32996)
                     /locus_tag="JX887_000336"
     CDS             complement(31983..32996)
                     /locus_tag="JX887_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1256352.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(33077..33676)
                     /locus_tag="JX887_000337"
     CDS             complement(33077..33676)
                     /locus_tag="JX887_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAX1256353.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            33862..34563
                     /locus_tag="JX887_000338"
     CDS             33862..34563
                     /locus_tag="JX887_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256354.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            34573..37284
                     /locus_tag="JX887_000339"
     CDS             34573..37284
                     /locus_tag="JX887_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAX1256355.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            37735..39363
                     /gene="treC"
                     /locus_tag="JX887_000340"
     CDS             37735..39363
                     /gene="treC"
                     /locus_tag="JX887_000340"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAX1256356.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(39423..40604)
                     /locus_tag="JX887_000341"
     CDS             complement(39423..40604)
                     /locus_tag="JX887_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAX1256357.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            40856..42379
                     /locus_tag="JX887_000342"
     CDS             40856..42379
                     /locus_tag="JX887_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAX1256358.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(42448..43176)
                     /locus_tag="JX887_000343"
     CDS             complement(42448..43176)
                     /locus_tag="JX887_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1256359.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(43189..44469)
                     /locus_tag="JX887_000344"
     CDS             complement(43189..44469)
                     /locus_tag="JX887_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAX1256360.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(44610..45212)
                     /locus_tag="JX887_000345"
     CDS             complement(44610..45212)
                     /locus_tag="JX887_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAX1256361.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            45457..45663
                     /locus_tag="JX887_000346"
     CDS             45457..45663
                     /locus_tag="JX887_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256362.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            45975..46694
                     /locus_tag="JX887_000347"
     CDS             45975..46694
                     /locus_tag="JX887_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAX1256363.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(46775..47458)
                     /locus_tag="JX887_000348"
     CDS             complement(46775..47458)
                     /locus_tag="JX887_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAX1256364.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            47677..49863
                     /locus_tag="JX887_000349"
     CDS             47677..49863
                     /locus_tag="JX887_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAX1256365.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            50209..50619
                     /locus_tag="JX887_000350"
     CDS             50209..50619
                     /locus_tag="JX887_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAX1256366.1"
                     /translation="MIKVYTSPSCTSCRKARAWLKANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            50633..50989
                     /locus_tag="JX887_000351"
     CDS             50633..50989
                     /locus_tag="JX887_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAX1256367.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT        16852 a         9073 c        10262 g        15407 t
ORIGIN      
        1 ggatgtattt atcccttttg cctaagcacg taaaagcttg tatctatgat aaataaataa
       61 acatagcaag gtaaaccagc caatcaaagt aagagaaaga atgaaataga aatagattgg
      121 cgtttgataa tgaagcgtga gctcgttgat tcctttttgc tgcttcacga ttggggtccc
      181 gatatctgtt acttcataat cagtcaatgt ttttccattt tgctgtagca cagtccgatc
      241 gtagacgata acagggatat gaacagtttt gtccccagtg tttttccact tgattgtcaa
      301 aagaccgcct ggatgtgttt ttataaaagt tgtttcgttt tctagtattt cttcgttata
      361 ccggtcgtat ttattgtctt ttgtctcctt atagattggc agatagtcag gtgtggtttt
      421 ttggaaaacg aacaagctgg tagacatatc tttgctgaag aatgttttcc ttgcttcttc
      481 cggcgtatcg aatagataag tatgtcgact gacaaatgtt tcattttccc acttttccag
      541 atgctggtat aagttctgga tcgtctgtgc tgaaaaaata agaatgccaa atatacttaa
      601 aagacggaac cacttttgtt cagaccactg gttcagtgaa agggcaaggt aaagtagaag
      661 caatagcgta aatggcacga aaaatcgaaa tggaaactgg atcaaactaa taaaaggcac
      721 atttttttcg atcaatgtcg tccatggaat caagctagta gaaagaaaaa agaaaacaag
      781 acttgtgtac aacacgattt tttggaataa ggtgttcttt tgttgaaaga aaataaaaag
      841 caaaaaacct gataatatca atataggaaa ggccttaggg taatggagcc aataactgcc
      901 atccagatct atcgcctttt gactcatttc tctgttaaca aagggaggaa gaatcttatt
      961 cccactgtaa acaatagcta atcctgccca aatatttgct gtcagaacaa aataaagcaa
     1021 gaccgactta atcagttgaa gcagtgcttt tcctttttca gtctggttaa aaaagtaata
     1081 aagataaaaa gggatataca tcaaagctaa catgatcgaa gacagtaaat ggatctgtgt
     1141 cataagtccc actgagacag cgactttgat aacagggaac tttttatgaa ggacgaaatc
     1201 agcaataggg atcatacata aaggataaaa acaagtcccc cagctagtga atccttggtt
     1261 gatagaccag tattgaatag aatacgtact catgaataaa acggctactg gtacacttac
     1321 ccaatttcga acattgacat atctcagtaa aatcagcata gaaaatcctg aaataagata
     1381 aagaatgaaa tttgaaagaa tctgataatg aaaccagcta cctgcaagca acacgatcaa
     1441 tccttgtaaa taagcgaaaa atgggccgta aacggcattc acgatcctgc cactttgctg
     1501 gaatccataa agggaaggaa aataatggaa atccccatat ttaatttgtt gcgcggcatc
     1561 atagaaccga ttgtaatgga atggggcatc agcacccaaa attagtttat gtgtgaataa
     1621 atgaggcatg agaaatgcca aagcaatgaa aaaaattgct aaaaatgggc catatttttt
     1681 caattgtcga actcctttgc aaactttaga taaattcatc atatatccta tgcgagaggt
     1741 aggcaagaaa ttagaaaatt catgaaaata tttatgaatt ttacaagaaa aacataagtg
     1801 aaagttctaa ggagagagga tgcgacataa gttttgttgc atctccttgt tttgaaacag
     1861 aatttttctt aatactcgaa acaaagtagc tttttcatga cctctcggta aacggtgttc
     1921 aatcagctgc ttctcggtaa taagctcact agcctagaaa atatgagaag ctattttctg
     1981 actagcgctc ttattactca aagcataacg cagttttcac aacctcttcc ttaaacggtg
     2041 ttcaaaagct tgcatctgcg gtaataagcc caacccaaca aaaaatatga gtagctattt
     2101 ttttgggctg tacttattac ttgatgcagg acagcttttt cacaacctca tcggctttca
     2161 ttttctattt ttttcctgaa cccatataat aaaagaaaga acaaaaaaac ttgcaaggga
     2221 ggacacatgt gaagcagagt aagcaaaaac agtctcgtcg acttttgttt cgtttgtttt
     2281 tattaatatg tatcgtcgta gggttactga tcgctttata tccattttat gtggattctt
     2341 taaatagttt tattgatcaa aaacgtatcg aacaagtaca aaaacggacc gcagctgaaa
     2401 ttgaagtgca gcgaaagaaa atggaggaga aaaaccaacg attaactgac caaggattca
     2461 atcctggtac tgatcctttc aatgaaaaga acagaaatga aagtacaaca tccagccaat
     2521 tagaggaatg gctgatcgga agtatcaata tacctaagat ccaattaaat atttcacttt
     2581 atgatcggct caatggtagg atccttgaaa atggagcagg cgtcttgcaa ggaacctctt
     2641 tcccgcttgg tggaaattcg acgcattcag tgatctctgc tcacagcggt ttacctaatc
     2701 gacggttatt taccgaatta gatcgtttag aaaacggaga cacgtttatt ttgactgttt
     2761 tgggggagaa attggcttat caagttaaaa atatacaagt ggtactgcca gatgacacgt
     2821 ctgttctaac gatttcagaa ggagaagact tagttacctt gcttacatgt acgccgtata
     2881 tgatcaacac gcatcgtttg ctagtgacag gacatcggat tccttataac gaatcggtaa
     2941 aaaaagaaga aggaaaagga aatcaggaaa gaaccatgcg gcaatggttt attcttgcag
     3001 gaacgataat agctgtagtc atactgttag tgtttatcgg acgactaatc tatcagtata
     3061 gattaagtaa aaaagtgctt gatttttcat ttattattag tgattcgtca gggaaaccgg
     3121 taaatggtag ttcattcatt ttgaaacata agaaaaaaac acttactaga aatggtgtgc
     3181 cgttttcagt acaaagcgac catcatggga aagtcaagct ggatcaattg cctggtggaa
     3241 cttatcgaat cgtttcagct gatgatccta aagttgctgt ttcttttggt attagaaaag
     3301 taaaacaaga gaagatatac ttttttgagg ggcgaaaact tgtaaaagag cttcaaaaaa
     3361 atggttttta ttttaaaatc aatgaataag taaggagaga aaaaatgatc cgcacaacaa
     3421 caaaattgtc tgccaaagaa ctggaatctg ttctatcgat ttggctgcat gctaacttgg
     3481 attctcatga attcattcca tcaacttatt gggagaatca agtagaatct gttaggaaag
     3541 ctttaccaga tgcagtgatt tacttagcag aaatagatca agaaattatt ggttttgctg
     3601 gggtgattga tcagtttatc gcaggaatct ttgtgaaaag ggaataccgg caacaaagaa
     3661 tcggtacgca actaatgaaa aaaataaaag aaaccaataa aacactgact ttgacagtct
     3721 atcaaaaaaa tcaatcagct attcatttct atctttcaca aggttttaca attcaaacac
     3781 agcaaaaaga tgaagcagta aatgaggagg aacttgtgat gaaatggaat caaaacgctg
     3841 atttttgatg aacagaataa cgaaataatg ctcccagcct aattttttgc tgggagcatt
     3901 atttcatttt gaagtcacta atttaactgt gtgaatatgc agttgttaca atctttgata
     3961 aacggtgttc aatcagctga ccctcggtat tagctcaaaa aacggcaaaa tatgaggaac
     4021 tatttttcca tttgtttctc taatactcag gtcaaaacgc tgatttcaca acctcttgat
     4081 aaacggtgtt caaacggctg cttctcggta ataagcccac tagcctagaa aatatgaaaa
     4141 gctattttct aactagcgtt cttattactc aaagcataac gctgatttca caacctcttg
     4201 ataaacggtg ttcaatcagc tgaccctcgg tattagctca aaaaacggca aaacatgagg
     4261 aactattttt ccgtttcttt ctctaatact caggtcagaa cgctgatttc acaacctctc
     4321 tttcacaacc ttattttact cgtttataat tttcatcgaa gtattttccg ctacggatat
     4381 catctggcat tccatcgtat ggttcttcgc taataacatc ttcattgtct atacctgcat
     4441 cacccatata agtgatcgta gcaaattcag gaacaagtaa ttttggataa gtttcatatt
     4501 tttcacgagc tgcttccatt tctgcgatat gttcgttttg gaaagtaaca gtgatttctg
     4561 gatgttcttc aacccattta gggaaaaaga tcattccgtg aagtttcttt tcatttggca
     4621 taaagtccaa tgccacgtct gtccctgttg gctctgtcca agtgattttg aatacgccgt
     4681 ccgtcaattt aacgatatca gcttcttggt cttttaccca acggcctttg accattccgc
     4741 catggatacg gtaatcaaca gtatggtcat ttttggcata ccattcatat tcccaaccat
     4801 tgtcatacgt atagataaag tgagttccaa taaaatcttc caattcttta aattctttca
     4861 tgtttaagca tctccttata aattaaaaca tgtaataaac tacatgtttt cgattactca
     4921 tttatgatag aatggattta aagatttgtc aaggagggaa aactgatggc aagaaaaaat
     4981 acacttcgat atattttgtt agggttatta agtaagaaga agatgacagg atatgaattg
     5041 aatcaatcgt tcaaaaatga aataggagaa ttttggcaag caaaacatag tcagatttat
     5101 cctgaacttg caaaaatgga agagcaagga atcattcagc atcaagtaga gatcacaggt
     5161 gaaaaattgg aaaagaaagt ttatgaatta acagaagaag ggaaggaaca attggcagag
     5221 tggattcata cacccaccaa tgaactaccg gttaatcgag acgaatttgt tctgaaattg
     5281 tatttcgtca aagacgtgaa tgatccggca ttagtagaaa ttattcagca gcagcgtgac
     5341 cttcatgaag aaaaacgact tcatctatta gagcgaaaaa aaacgatctt tcctactgaa
     5401 aaagaaaaac atgaaaatta cggacactac ctgattttag cgcatgcgat caatcgggaa
     5461 acagaatatg caaattggct aacagatgta ttagaagaaa gtaaccgaaa aaaataaaaa
     5521 aatatccgaa cagtgatgga gaattccttt ctatatgaaa gaaacgcaga tcaccgttcg
     5581 gatattctta tgttcaaaca ggcctttttt caagtattta tgtagcatct acttattaaa
     5641 aagcttggta cttaggagat tagtggcgtt tagagttctt ttaacaactg ttcgtagtca
     5701 gctttttcat cgacaggaag gagcttgtaa gttaattcgt ctgtctcgtt gtcatgaatg
     5761 atgtacatct tagcattctc ttctttgaag ttaccgattt gtaaaatcgt atagcgttcg
     5821 tcgatcaatt cgatatcttt gattgctttt gaaaaaactt tacggacatg gtgcattttc
     5881 ttttggcgga tttctgcctt ttctgcagct tttgacaaag taaatccgtc atctaaatat
     5941 tttttgatca gttctacttt tatgactgta ggtaaacgat attttctagg acaattcgca
     6001 tcagcttcga tcgaacgaat gaatcccttt tgttcccaat accttaattg acgtggagac
     6061 acacctacga tatcacttaa ttcactgatg ccaacaacca attgatcatt ttccaacaaa
     6121 cgtttaaggg aagccccaac catttttgtc actccttttg tcctcttgct tcccttaatt
     6181 atatccgtat taacttatgt gtcaagtagg ttgacaaata gcgaatttag gactaaagta
     6241 ttctagtagt ttcagaaaaa attcagaaag aaggagaaat atgagtaaca accaacccgt
     6301 agatatttac ggaaaaccat ataatcggac acttttagtt gttgtcttat taattggtac
     6361 attttgtacc gttttgaatc agaccttatt gacgacagct tttcctacat tgatgaaagc
     6421 tttcgatatt tcagcgtctg atgtgcaatg gttaacgact ggtttcttgc tagtcaacgg
     6481 gatcatgatc ccaataacag catggctgat caataaattc agttcaagaa atttatatct
     6541 ttctgccatg acgatctttt tgatcggaac gattacttgc tttacagcac ctaattttag
     6601 tacattacta atcggtcgtt tgatccaagc ttgcggtgtg ggagtatcga tgccattatt
     6661 gcaaaatatc atgctatcta ttttcccgcc agaaaaaaga ggatcagcaa tggggatgtc
     6721 agggatcgtt attggacttg ctcctgcttt aggccctaca ttatctggtt atatcattga
     6781 taactaccat tggcgtgact tgtttggtat ggtactgcca atcgttgttc ttgtcttggt
     6841 tttagcattc ttcctaatga aaagtgttat tccattgtca aatcctagca ttgatatttt
     6901 atccgctatt ttatcaacga ttggattcgg tagtttactt tacggatttt ctagtgtagg
     6961 agatgacggc tggggaagct tgaaagtaat tggtttctta gttgttggtg tgattttcat
     7021 cgccttgttc tcatggcgtc aattacattt ggaacatcca ttcttggaac ttcgtgtatt
     7081 caaatcatct acattcacga ttgcagctgt tttagctggt gtaacaaata tggcgatggt
     7141 aggggcagaa atggtcgtac cattgtatat tcaaaatatt cgtggagaat cagcattcca
     7201 ttctggcttg atgttgttgc cgggtgcatt gatcatgggg gctatgatgc ctgtgacggg
     7261 tgcgattttc gataaatacg gcgcgaaacg tttagccatc acagggatgt tcattttgac
     7321 agcggcaact gcaccatttg ctttcttgac aaaaacgact ccagttttat atatcgtgat
     7381 cctttatgcg atccgtatgt ttgggatctc catggtcatg atgccggtaa cgacttctgg
     7441 tatgaatgca ttgccaaata acttgatcag tcatgggaca gcggtaaata atacattccg
     7501 tcaaatcgca agctcgattg gtacagctat tttgatcagt gtgttgacga atgtgacaaa
     7561 agcaaatatc ccaagcaaat ctgtattgga taatacgcca ttagcttata aagatcaggc
     7621 aatcaatgcc acactgtcag gttaccatgc cgcgtttatc gtagcgatca tctttgggat
     7681 tcttggcttt attattgcct ttttattgaa gaaaaaagaa cctgttctaa tgaaagcggg
     7741 ggataatgca tgattattgg agttttgatt gtcagcttgc ttgcttttgc tttaacgaac
     7801 gtgttcgcta aaaaaacatg gcaaaccttt ttatctttga ttttcggact aatcttcgtc
     7861 gcttcactaa gtttgatcgt cgctaatttg tccaatcact ttggaatgga aaaagtaacg
     7921 gaaacaaaaa cagaaaaaat tgtttccagt gctgattccc aaggagcaga tatgcttttg
     7981 tataaagctt tagggaatgg aaaagaaaaa gtgtatcttt accgaacaaa tgaaaaacaa
     8041 gaaaaaccaa aagcaactgg tacggataac gaaacaaata aagtagaaaa gacagacggc
     8101 gatgctgaaa aagtgacgaa aactacttat tgggaataca aaaacgacat gtataaattc
     8161 tggttcaata ttgctgataa caatcacgaa tatgacagcc gagtgaatac attcaaaatc
     8221 ccagagacat gggtagaatt aagtacggac caagcagcca agttagctga attagtgaag
     8281 aaacagcaaa gtacgatgga aagtgaagca aaagcttatg ttcaagacgg tatggtaaaa
     8341 gcaatgactg aaaatccaaa aatgagcaaa gcagagcaag aacaacgtac gaaagcctta
     8401 gctgctgaat tccaacaaca agcattcgca aaattagtga aagaagcaaa aggcgaataa
     8461 tattttgaac accatgtagg aggttgtgaa aaagctgctc tgcatcaagc agtaagaaca
     8521 atcagataaa aatagcactc catatttttc atctgattgg gcttagtgcc gtagatgcaa
     8581 gcttttgaac accgtttaag gaagaggttg tgagcctgcc gtttaactct gagtcacaag
     8641 gagcaatttc aaaaaacagc ttctcatgtt tgttgactat tgtgacttgt gaccgaggag
     8701 ttggcaggag aacaccgttt attcgaaaaa aggaactgcg acaagacttt tgtcacagtt
     8761 ccttcttttt tttgctatgc tatactagat gtaaaaaata ggagaaataa aatgagggaa
     8821 atttattctt ttgaatcaaa aatctatgct tccgaagtcg gcaagggcgg ggcatatatt
     8881 atttttccgt atgatataag aaaagaattc ggtgctggaa gagttaaagt ccaagcaact
     8941 tttgacaatg tgccgtatga aggcagtatc gtgaatatgg gcgtgaaaaa tccagatggt
     9001 tcagtctgct acatccttgg actacgaaaa gatattcgta aaaacatcgg aaaagaaatc
     9061 ggtgatattg tagcagttac agtgaagcaa aaataaaaga ggttgtgaca aaagacgtgt
     9121 cacaacctct tgataaacgg tgttcaaaag ccagtttctc ggtagtaagt caaatttatg
     9181 caaaaatgtg gaaacccatg tttacaaaat ttttcttact actcgaaacg aagcggcttt
     9241 atcacaacct cttgataaac ggcgttcaat cagctgtccc tcggtattag ctcaaaaacg
     9301 gcaaaatatg agaagctatt tttccatttt tttctctcat actcaggtca taacgctgat
     9361 ttcacaacct cttctttcat aatggttttt caccatcttt ataataaact ggttatttga
     9421 tatggaaatc tattttttcc aaccaatcta aaatcttgta acctaactct tctgacatcg
     9481 gaaaagaggc gttgatttgt gcattggaga tatggtcaac atggataccg gaagtgatcg
     9541 tacaacttcc cggaacggca gttttgatga tcacagctat tttttcggct aagacatcgt
     9601 ctttatggaa ccgaccatcg tggctaggga aacgtacagt ttgcatctct gtatcacgag
     9661 aaaatgtagt gactgttccg atatgtggtg tatctccgcc tgttaaagtg atcaataagt
     9721 ctttaccgat tactttaaca gcagcttgga tcgtgaaacc tagtttggtt acttcaacta
     9781 tcgtttcttt ttccatatta atcaccctgc caacgttttg aatgctcatt tacaatttca
     9841 aattgatcca aaagtttcat tgtatggtga ttaacaagat cttggatcgt ttgaggctga
     9901 ttataaaaag caggaattgg tggtatgatt tgcacaccta gtcgtgctaa tttagtcaag
     9961 ttttccaagt gaatggcatt taatggcgtt tcacgaggaa caatgactaa ctttcgttgc
    10021 tccttcattg ttacatcagc agcacgtgca atcaggttgt cgcctaaacc aacagagata
    10081 cctgcgactg ttttcatact tgccggtacg atgatcattc catcggtcaa aaatgatccg
    10141 ctggcgacag cagcacctaa atctttgttt gaataatggt aatcaaacag gctttcgaat
    10201 tcagttagtg ataagtcgga ttccagcttt aagttctgtt ttgcccatgg actgatgatt
    10261 ccgtgtgttt ctatcatcgg atattctttt agtttcttca ctaggttgat ggcataaatg
    10321 gtgcctgaag cgccacttac accaatcacg atttttttct tccgttgtgc caattgttcc
    10381 attttccgca ctccttttta tgatgtcaaa acagttgcag atcattcatt atttcaaata
    10441 tttttcccaa tcttctactt cttggaattt tgcacgtaca aaatgttctt tcatatcgaa
    10501 aggaactgta ccgtcaaaga tagtttttgc acttatccca cggaaacgaa tagagccagg
    10561 attatattct ggtaattctg atgggtccaa tggatggttc ctcattcctg ggatcacgat
    10621 gatatcttta tctccttgga aacgagtgtt gaaagtccaa actacatcgt tcatgtcgaa
    10681 aatatcaaca tcttcatcga ctaaaatgac tgtcttcaat tctttgaagg ctgataaagc
    10741 aagaatagct gcttgacgct gaataccttc atccgcttcg ttttctttac ggatttgcat
    10801 gatggtcatc aatttaccac cacctgcagg aggattgtag acatttacta cttttcctgg
    10861 aatagcttta tcgaccaagg caagaatact tgcttctgta ggaataccgg ccatagatac
    10921 gtgttcttca ctgggaccaa tcgttgtttg catgattgga ttgtcttttc ggtgagtaac
    10981 tgctttgact ttcactactt gtacagctgg attagcatcc ccagtatagc caggaaattc
    11041 tggcattgct tttcctgagt tcgtgttgat atcttcttgc attgtttcat ttggcatgat
    11101 ttctgcttca atgatgaatt cagcacgagc aatacccact tcatcgactg ctataccatc
    11161 aacgatttga ataggttcgt tacgcaaagc tcctgcacac catagttcat tgtagccaag
    11221 tggagtggta ggtggttcga aagtcgtgcc aatggcaatt gctggatcta aaccaatatt
    11281 gatagtgata ggcattggtt tattcaaggc ttcgaattgt ttttggaagt gaccaatgtg
    11341 gcgtccgcca ggcatgatgt acataccgat cgtatcttta tcttctagaa ccatacgatg
    11401 gatcgttaca tcgctcattg ttttttctgg atctgatcct aagactacac ccattgtgat
    11461 gtatggacca gcatcttcag gagtatttgt aggtgcaggc aaaatgttgc gaatatcgaa
    11521 gtctgcatcg gtagctagat gaacgacttc ttgtgctgga gcgtctgctt tgtctacttt
    11581 cacaggtttg attggatttt ctacagcgtc tttcaagaaa cgaccaagtg ttcgataatc
    11641 atggtgcaaa atttcaccta cacgtttacg actagccatt gttccgatgt tcacacgtgt
    11701 gccggggaaa cctttgatat tgttgaaagt catagctggt ccttcttgag tcggacgttt
    11761 tactgtaccg ccagcaccga tataacggta aacaccagat aattctgctt caggatcgat
    11821 ttcaatatct gtttcgtgat attgacctgg aagtgttttt agttcttcga tgacttttct
    11881 taaatcatac ggttgatctg tcatgagaga ttcctcctta gttgtcttta cctatctata
    11941 gtaaaaggtg aaaaagagga aaacaattca acttgttcgg taaagtattc tacaatggaa
    12001 tggatgcgtt tttttgataa tagaataaac tatgatatac ttatcactaa aagaaagcgc
    12061 atacttagtg ttggaggaag gaaagtgaaa aaaatggagg agtcatttcc taaagcagta
    12121 aaagtggaaa atatagcgaa tattttgaaa gttacatttg aaaacggaga agtaaaatac
    12181 gtgaaatctc attggacaga agagataacc gatgccttgc aatttggaaa aaaaggaaga
    12241 ggaaaaagaa aaaatcttct cgcactttct cgtaatatgt ggattgggac tgaagtaacg
    12301 attgaagcag atggaacagt attcataaat ggaaaagaca ggtatacgcc agaagagttg
    12361 tggtacaaag gaaagaaaag tataccagaa ttataaaaaa taattaaaaa aaacagcgcg
    12421 aaacaaggaa catattactt cctcgtttct tgctgttttc tactatttca gcgctcttat
    12481 gactcaaatc taaatgtggt tgtcacaacc ttattctgca cgcaaagcga tagcggcgtc
    12541 ttttttcgct gccattcgtg caggaagatg accgccaagc atcgtcaata tagtagagac
    12601 gatcactaga ataatcgcat ggacaggatt tagttgagca acatttttta gatccgtcat
    12661 gttgtataag atgctattga tagggaacgt agctagccat gcaataaaca cacctaatat
    12721 cccagaagaa atacctaaaa tacacgtttc tgcgtcaaat acgcgagtga tgtctttttt
    12781 acgtgcacct aaagctttta gtacaccgat ttcttttgtc cgttcaatca cagatgtata
    12841 agtaatgata ctgatcatga tcatacttgt tactaaagag atccctgcaa aagcaataag
    12901 gacataagtg atagcatcca tcaatccgcc agtcagttca gtcatcgttc cagctaaatc
    12961 agtataaatg attttatctt catctgattt gcctttattg taatcatcta gataatccaa
    13021 gatcttttct ttgtcttcaa aattgttcgg ataaatcatg atacttgaag gcaagctgtc
    13081 tccacctaaa taactaagca atgtttgttt ggcattttcg tcaacttttt cagtagttaa
    13141 gacatttaca ccactgtctc tttgagcttt gacgatttct gattctttgt tttcgttgac
    13201 gatttgagtc gttaattgat cgctataagc gattcctgga gataagagat tcattgtaga
    13261 agaagatttc acgcgtagga tccccgagat cttcaattca tcagaagcat tctgatacat
    13321 cgcatcataa tctgtattag ggataaaatt cccagttgga agttttgtat agtaagtatt
    13381 gttgtttact aatttgaatg ttgtaccaac gatatcatca aaatcaagtt tttcgtcttc
    13441 tttcacatca aatccaagat tcttcaatgc gttgatatta gtattattat tgccgtctac
    13501 gatcagcacg acatctgttg ctgaggctgg ataacttccg gcaagtaaag aataattgtc
    13561 ttttaaaaag ttttctttgc tagtgtcaag ctgtgtaggg aaacttgaca ctcccacacc
    13621 tgtcattgct gacatcgtac tagataaaga aagagattcc gtatcaggat tttgattcga
    13681 gaagctgaca ggctgtactt tgccatttac atcacgtaaa agattgattc ctgtagtacg
    13741 ggtaaatccg atattattac ttaagttagg atcgatgtct gttacgtaat cgacgtatgt
    13801 ttgatcaatc ttattcgtgt gctgtgcttt atcttcttcg ctgacttttg cagtaatcgt
    13861 tttgctgtct ggataatccg ctttgcttgc acccaatccg gcatcgtcac gagtctggtt
    13921 agtcgttacc ttagaaatag taatcggaaa tttcgccatc gtttcagctt gcgtgttatc
    13981 gatttgtttt tggaatccag aagaaaggga cagaacgatc gcgattccga tgatcccaat
    14041 actggaagca aaggaggtca agaaagtacg tccttttttt gttcggatat tgttgaagga
    14101 aagctttaac gctgtccaaa aactcatctt tgttctgcgt aagttaaatt gatcatcttt
    14161 tggtcgttcg atgtgaggat gggaatctgt taagatctta ccatcagaaa attcaatgat
    14221 tcgatctgcg tattgatggg ccagttcagg attatgtgtg accatgatca ctaatttttc
    14281 tttcgataac tcttggatca attccatgat ctggatactt gtttctgtat ctaacgctcc
    14341 ggttggttca tcgcacaaaa ggatatctgg gtcattggct agtgctcgag cgatggccac
    14401 tcgctgcatt tgtccaccag ataactgatt tggcttttta tgcatatgat ttgtcaagcc
    14461 gactcggtgc aatgcatctt ctgcccgttt tcgtttttcg tctttagaaa caccacttaa
    14521 tgtcatccca agttcaacgt tttcaataat gcctagatga ccaatcaagt tgtaactttg
    14581 aaaaatgaaa ccgatagagt tgtttcggta ggcatcccag tcactgtcct taaagtcttt
    14641 agtagacttt ccgttgatta ccatatcacc ggaatcataa ttatctagtc caccaatcac
    14701 attcagcata gtcgttttac cagaaccact aggacctaaa atcgctacga attctttttg
    14761 tctgaaagcg acagacacac catccaatgc tttggtggtg gtttcgccga ctttataata
    14821 tttttttata tcttttaatt gaagcataat cacccttctc ccgtattgaa atattcggta
    14881 tactaataag tatatcagaa caatgatcgt agtatacgaa ataaatgtta actgaagatg
    14941 aactacaaga aaaaatctag aaatttttca aaaaacagag ggagatcaat gaatcgtatt
    15001 ttagtagtag aagatgatcc gcaattacag ttgctttacc gttctgtgtt ggaacgagcg
    15061 ggcttttcag tcatcaccgc attgaatgga gaggatgcgc tgaaaaaact agaagcgaca
    15121 cgtatagaat taatcattac agatatcatg atgccgaaaa tggatggcta tgacttgcta
    15181 gactcattac gtagcaccag atttgacaca cctgttctaa tgattacggc aaaggccgat
    15241 tttgaggata agaaacgcgg gttcaaatta ggagcagatg attatatgac aaaacccatc
    15301 gatgtcaatg agatgatcct acgtgtggaa gcattgcttc gacgttcaaa gatcaattac
    15361 agcagtagct tgataatcgg acaaacaaaa ttagagctag atgcttatac agtgttacaa
    15421 gatcagcatt cgttgattct gcctcaaaaa gaatttctgc ttctgtataa attactgtct
    15481 tatcccaaca agatcttcac tcgccaacag ttgatggatg atatttgggg attagatacg
    15541 aatacagaag aacgaacgat cgatgtacat atcaaacgtt taaggacccg ttttgaaaag
    15601 acggaagatt ttcaaatcat cacagtacgg ggactaggct ataaggcggt tatttaaaga
    15661 tgaaaaaaaa gctattttca caattatgga tctattttgc tagtattgtc ttcatttcga
    15721 tcttagtgac actgctgtgt tttctcggtt ttattttctt attgtctcga cattctatct
    15781 cgcctgctga atcggctgga aaaccaacgt tatacccgtt attcgtcttt gcggggttca
    15841 gtatggtcgt gggtacagga atatcgattt ttgttgggcg gcgtatcctg catccaatca
    15901 gtgcgctagg gacaaatatg agtctggtag caacgggaga tttttcgatt cgaatggatg
    15961 aacagcagaa agtagcagaa gtacagcaac tgtataaaga tttcaacgtt atggtccaag
    16021 aactcaatag tatcgagaca ctgaggaatg actttgtgtc cagtgtatcc catgaattca
    16081 aaacaccact agcaacaatc caaggatatg ttcaattgtt acaagcccca aatctctctg
    16141 acgaagaacg ccaaatattt ttatatcgga ttatcgaaag tatcacgcag ctttcacaat
    16201 taacagagaa catcttaaaa ttgaacaaac tggaaaacca gcgtatccaa ctggaaaaga
    16261 aagagtatcg attagatgaa caaatcagag aagtaatcgt tttttttcag cctaaatggg
    16321 agaaagaaca gctagaattg gatatcgaac ttgctgcagt aaattacaca ggcaatgaag
    16381 agtttttgta ccaagtgtgg ctgaatatca tggataacgc cataaagtac aatcaaatca
    16441 atggacagat tcatatcaaa ctatttgaga cagccacaga gattgtactg gaagtgaccg
    16501 attcaggtgt aggaatgaat gaagagacca gagatcgaat gtttgaaaaa ttttatcaag
    16561 gagatacaag tcgtcaaatt tctgggaatg ggctaggact ttcactggtt aaaaaaattc
    16621 tagaactgca tgatggacgt attgattata gcagtatcga aggagtagga acgacagcaa
    16681 tgatacggtt aagtaaacaa taggaaaaag aataaaaccc ctaaaaattc tattgaaggt
    16741 ttttaggggt ttttagtcgt ttttttgtga ttagggaaat gttcttacgg ttcttttggc
    16801 ataaaaatcg ctgctttctt attgaactac gagaaatgtt agaggtgtca ttgaaacaag
    16861 gacatgatgc aagaaagaga gcgaaagtca tgcgtcgctc tctttttttg ggtggataga
    16921 tggacagaaa atgtagggct tagttttctt cttgatttaa atactcccaa aatgtatctg
    16981 aagccaaaga atgctcaccg actttacgag taaatgcaag ataactctct gttgttggag
    17041 aaatagggag aatcacagta ttttctttta atagattctt gactgttttt tccataacaa
    17101 tagcaatccc catgtcattt gcaatcatat tgatgatcaa gtcgattctt gctcctttat
    17161 aagagatttt tggttcaaat ccagcttcgc gacacagatc tagtacaggt tgatacaagt
    17221 tcgtagtggg gccaaggagc aaaaagttct cctttttcag ttcgcttaga tccaatttct
    17281 ttttactagc taaaggatga tttttaggta gaactgctac aaaatcgtct gtttcagtag
    17341 gcaaccactc aatcgaactt ggtggggcct ggaaacttct agcaaagtgg atcgtgtcac
    17401 tatgttcatt ggcgtcattg taagttaatt cgacactttc cacttctttc aactggactg
    17461 taaattcagg atggcgtttc aaaaactcgg tgattttgga aaaaccttta taattgatca
    17521 ttgtcggtat cgttaagata tttaatgaaa gattgttgtc tttcgtatag gtttcaagca
    17581 cttcttgcat agcatggtat tgttctacga cattttttac atatgggagc aataagcttc
    17641 cagcttcggt caattcgatt tttctatggg cgcgttcgaa taatttgacg tctaattctg
    17701 tttctaacga aagaatctgt ttagaaatat ttccttgggt ggtgaattgt cgatcagcag
    17761 ttttggtgaa attcattgtt tcggctaaat caagaaaaac ttcgaattta tggatatcca
    17821 tcatattcct cctacttatt ccaataaaga atactttaac acaaaaaatg aattggtgta
    17881 atcttctctg tctgttacaa tctttcttgc agcgaaagca ataattacag aaatttttct
    17941 gatttttttc gcttcgtaga aaaagagagg agttttttga tgccaactgg agttttgatc
    18001 aatgtaggtt ccgttttgtt tggcggacta attggcggat tagtaggaaa taaattaagt
    18061 gaacatttta aagcacagct gacgatggtt tttggtgtgt gttcgatggg gatgggaatc
    18121 tattccattg cgccgatgaa aaatatgccg gctgttattt ttgctttagt gataggaaca
    18181 gcgattggtt tgattgttca tttaggtaat gggataaata agggggctgc gctgatgcaa
    18241 gtacctattt ctaaaatctt ccctagtgaa aagcttggta tgacccacga tgaatttatc
    18301 agcacattag tgacggtcat tgttctattt tgtgcaagtg gtacggggat ctatggaagt
    18361 ttagattctg ggatgacagg agacagtacg attttgattt ctaaatctgt ccttgatttt
    18421 ttcacagcag ctatttttgc gtgtaattta gggtatgtcg tttctgtgat agcaattccc
    18481 caattcatta ttttttatat tttgttctta ttggcaaaat ttatttatcc attgactaca
    18541 ccagacatga tcttagattt taaagcttgc ggcggattct tgatggtcgc taccggtttt
    18601 agaatgatca acgtgaaaat gttcccagta gctgacatga tacctgcaat gatcgttatc
    18661 atgccactga gctggatgtg gacaaattgg attatgccac tgttataata aaaatcaaag
    18721 agaagccatt ttttgctgac taaaaaggat caaatctttt agtcagtttt tttgtatttg
    18781 acaaactgat tttgaaacta tattatatgt tgtataatat agattgaaat aaaatattac
    18841 acttgagaat agaaggtgac gtaatgcaca tccagattcc aactgttctt cttgatggta
    18901 ctgtgctagc agcattaagc aaggaagata tgtatgggta tgccttaaca aaaatcgtac
    18961 aagaaagtct ctctgtcagt gaatctacac tatatccggt tttgagaaga ttgaaaaaag
    19021 aaggatatct tgagacctat gatgaacctt ttgaaggcag aaaccgtcga tattactcgt
    19081 tgacaccaat gggaagtcgt catttagaag aaattattga tgaatggatt gtttttcgag
    19141 attctttaga ccggttattg gaggagagca caaatgaatg aatatttgaa tgaagttgtg
    19201 gatcatcttc aagaaattcc tgaagacgat cgttttgatt tgatccagta ttatgaggaa
    19261 tattttttag attctggaaa aacattagat cagatcattg atgaatatgg tacaccaaag
    19321 cagtttgcct taaaattaaa aatcagttac ttttcagaag aagaacaagc agaaaacgag
    19381 ttagtgaaaa atccaaaaag acaaattcgc ctgatttggt taatcattat cggtttattt
    19441 gcttctcctg tcctcattcc actagcactg gggtttatat tggttattgg gggactattg
    19501 gttgctttac tagcgctcat ttttagtatc tatgttttat gtatcagtat cttaggtgtt
    19561 ggcctattca tgatcatctc aggaatcagt gtgtttggac aatcgattct gagtggatta
    19621 ttctttatcg gtgtcggtct gttcgccaca ggaagcgcag tatttatttc gccactgttg
    19681 ctgaaaggaa caaaagggct tttttatgtc atgatgaact ttgttaaatg gatgggacga
    19741 cgttttatta caaaaagaga tctgcattca gcgggcgttt gaaggaggac acataaattg
    19801 agattgaaac attttttgat taccggtatt ggtctgatgc ttactggtgg cctcctagca
    19861 ggtgcaactt atacattagg cgctcaaaag agtctgactt gggataatgg tcctcggttg
    19921 atcgatatgg ttactgagac aaaaaaaatc aaggatgcaa acaaaatcgt catccatgca
    19981 gaaaatcaaa cagtttcggt catacgcgga ttggattttg agataaaaac gacttatgat
    20041 aagacagaaa agccagaaat aaaggagaaa aatggcgtgt tgactgtgaa tgcagtcaaa
    20101 aaatcaacag gtgcaatcat tagtttagaa gacacaagtg cacaaatcac tattgttgtc
    20161 cctgcagatc atgaattatc tgaattgaca atcgaaggga ataatagtgc aattgatatc
    20221 aacgaagtat caatcaaaaa agtgaatact aagacacatg atggctgggt atcgttcaat
    20281 gaatttacag gaggaacaat aactgcgaaa gatgaattag gctcacttcg attagatgag
    20341 gccaatgtgg ataacttgat cgtcacaggt gaaaacagca acttccatct agaagacagt
    20401 ttgatcagca aagaaggaaa agtcatccta aacggtggca atttatcttt gcatgagatg
    20461 gaaaacagtg gctatactat ccaaacgtct ggtgaatctt atattgaaaa agactaccag
    20521 ccaataacaa atactttgtt agaacaagga cagaaaaagc taaagatcac tgctaaagac
    20581 acatcgatca atattacgac ggatcaagag gacaatgaaa cagattgatc ctgtactcaa
    20641 ctggatattt taagaaaaaa cagcaaagat ccttccaatc tttgctgttt ttcatcgctt
    20701 aacgcacata actatagtaa aataagaaag aaaatatcta aaaagaaaac agggtgaaag
    20761 agtatatgaa ggtagaagaa ggtcaaagag aaaagttaaa aacagaaatg gaaagattac
    20821 atacttatat cactcaacta agccaaacct tctatgatcc agacaaagaa aaagtgatgg
    20881 ttaattaccc gaacaattca gaaggtcgcc aattagagca agtgtaccat gaagttttca
    20941 aacatttatt gacggtgaag aaagagctgg attattattc tttaccgatt atcgatacag
    21001 gaatattgaa gtatgatggg aagaaggaac gatttatctt taaatctgtt cgggaagatt
    21061 tgcctctttc agcagggatg gatctagagg tcttggtaga agactatttt acagaagaaa
    21121 agcactgggt tcgaacaaaa ttggattatt taccgcaggc agccggaggg acacaggcaa
    21181 gcggttggta catcactgaa gacaaagagt tagaactaga aggtgtaatg gcgcgtattc
    21241 gaaaaaaaaa ttaaaaaagt aacattagat atttattgaa ggataaagga gcgcaggaag
    21301 tagcatgaga gaaaaaagag cattttatat caatggttat gcagggattg tcggattggt
    21361 cgtattagct ttagttggat tgtttttctt ctatttaggt atgtggcaag cgaaagtttg
    21421 ggcacttttt ttaagtattt ttctttggtt gatcacgtta ttgttgttaa gttcggcaac
    21481 tgtagtcagt cctaatcaag caaaagtaat tttgtttttt ggacaatatt taggtacgat
    21541 tcgagaaaat ggctttttcc ttacgatacc tttggcacaa aaaatgactg tttcgttgaa
    21601 agttcggaat ttcaatagtt ctgttttaaa agtcaatgat ttggatggaa accccatcga
    21661 aatctcagca gtagtagtct ttaaagtcgt tgatacagca aaggcattat tcgatgtagc
    21721 gtattatcaa gattttgtag aaatccaaag tgagacagcc attcggcata tcgctagcca
    21781 atacccgtat gatacattca atgagaatga tttgacgctt cgaggaaaca cgacggcagt
    21841 gtctgacgag ttgcaaaaag agctgcaaga gcgtttagca gtagcaggtg tcgaagtaat
    21901 cgaaacacgc ttgaaccatt tagcctatgc aacagaaatc gctagtgcca tgctccaacg
    21961 tcaacaagca aaagccattt tgtctgctcg acaaaccatt gttgaaggag ctgtcacaat
    22021 cactcaaatg gccttagagc aaatcgaaga tggacaagaa atcaatttca ccgatgatcg
    22081 gaaagtccaa ttgatcaata atttacttgt ctcaatcatt acagacaaag gaacgcaacc
    22141 tgttatcaat acaggcgaca tgaaagaccg taagtgacat actttttgta agataggaag
    22201 aaggagttta ggacggatta ttgtcttgaa ctcttttttt agttgtttta aagaaaatga
    22261 caaaattgaa agaagaatga tagttgattc gaaggcagaa ttgttcgctt ttttctataa
    22321 tcagtatata aagtaagaga gaaggggaaa aagtgaaaaa acttctgatc ggtctacttg
    22381 ttttcatcgt tgtggtactt gcaggggtga aaatcgcaga ttacgtagtt atgggtggag
    22441 aagaatacta tgtacaaatt acgacagatg gtacaaaaac agtttcaaaa tcagactctg
    22501 gacaagaaac agtcaactat agatatatcc tgcctggcta tacgaaagag ggtaaggaaa
    22561 aagaactgga cttcaaggga caattgactc gaccgcttcg taaaggagca tatttaaaaa
    22621 tcacctggaa caaaaataaa ggtgtcactt cgtatgaaga agtcgaaaaa aaagacgtgc
    22681 cgaaaacagc actggaaaaa ctaattaaag ggtagggaaa gaaatgaaca aaatagtcga
    22741 agtacagaat gtaacaaaag tatacggaaa aaacaatgag aaaaagacgc aagcattaag
    22801 cggcatcagc ttcgatgtag aaaaaggcga atttattggg atcatgggcg cttctggttc
    22861 tggtaagtcg acacttttga atattttatc cacattagat aaaccaacag atgggcatat
    22921 ccgaatcaat caaaaagatg tgaccacatt aaaaggaaat caactagcag attttcgtgc
    22981 gaatgagatt ggctttattt tccaagattt caatttatta gaaagcttga cagcacaaga
    23041 aaatatcgct gttcctcttt ctttacaagg cgtcagacca aaagaaatca agcaacgtgt
    23101 ccaaaaaatt gcagaacgtt tatccatctc tcatattttg gaaagctatc cttctgagat
    23161 ttccggtgga caaaaacaac gggtcgccgc cgcacgtgca ttgatcacac aaccaacgat
    23221 tctattaggg gatgagccta caggtgcgct ggattccaaa agtgcccggg atcttttaga
    23281 tacgatggac gaattgaata caaaagatca tgtatcgatt cttcttgtga cgcatgatcc
    23341 gttttctgca agttattgcc aacgtatttt attcatcaag gatggcggta tccatcaaga
    23401 agtgaaacgt ggagatcaaa gccgtgattc cttctatcga gaaatactat ctattcttgg
    23461 aaacttggaa cagtaggggg agattgacta tgctttggaa attatcactt actgggatca
    23521 agagccgttt aagagactac ttggtgttat tctcaggatt agttatggca tctgctattt
    23581 tttacatgtt tgaatcaatg gcaagcaacg aagctttttt gaaaagtaat acgatcgttg
    23641 cggctacagt tatcattttc cgattcggtt ctgttttact agggatcatc acattcgttt
    23701 atattttata tgcaaattcc tttttgatga cgatgcggca aaaagactat gcaatgttta
    23761 tgatgctggg agcaaaaggc agaaaaatcg cacagatgat tttttctgaa acattcttag
    23821 tagggatcgc agctacttta gtgggttcag ctgtcggtgt aggattgaca agtatcgtcc
    23881 accgattatt agtggatcag ttagatctca atatttcgca ttttacacct tttagtattc
    23941 acgggttgtt gatcactgtt ttgttttttg ctgttttgtt tttattagct gctgttgtca
    24001 atgctttttc gattgtcaaa aaaccgattt tagcattgat tcgtgcggat cagacaccaa
    24061 caagaatcaa gcagcataaa ttcttgtttt tccttgaagt agtactggga attgcttttc
    24121 taggctgcgg ttactatatg atgaaacacg tggggaccta tcaagtcttt ggtatagggg
    24181 tagccttagt tacgatcgta ttaggaactt atttcatttt ccattctgtg atcattttct
    24241 ttttatcatt actaaagaaa tcagaacaga tttcattgaa aaaattgaac aatttcacat
    24301 tgtcacagtt aaactttcgt attcgtgaat atacacaaat gctctcaatg gtcgctatgc
    24361 tgtttgcctt ggcactgggc gctttgacgg taggattagg ttttaaaaat gaaattgcag
    24421 acttgacaga aaacaattct ggatatgatc tagtgatgaa taatcctcgg gcagaagatc
    24481 agcaaaaaat caaagaactt tcaccaacac tttctgcttc ttatactcaa aaagaagatg
    24541 cgggaacgat ttactataat gcaagtgaat ttgcggctca accattgatc atgataaaac
    24601 atgaagatgg aacaccgccg aagatcacga aagaaaaagt tcctgctaaa aaaatgaatg
    24661 aactgactgt acaagaggaa cttcgaagct atgaattgcc ggaacagcaa gaaaaagaaa
    24721 tcaaggtagt cagtcaatca gaatttgatc aactgaactt gccacaatcc actttacagc
    24781 tagttcaggt aaaagacttc caagcaaacc tgaaaccaat cgaaacactt gttgctcaaa
    24841 ataaaatgaa caatccatct ttgcaaaaag tagagtacag caaccagaaa tatgaaatgt
    24901 atgaagtgta taatggtcta ttctctggtt ttgaatttat gggattcttc ctaggtttag
    24961 ctttcttgac catgcttgct agctgtttga tgttcaagat cttgtcagga agcaagagtg
    25021 acattgctcg ttatgaaatg cttgaaaaga taggaacacg acgcgggttg cttaaacaat
    25081 cgatccgtag agaagtaggc gtgttattct tagcaccagg aatcttaggt gtagtccatg
    25141 tcttattcgg attacaaatg tttggtctat tcatgcaaaa tccatacaaa gatatttggg
    25201 ttccgtttac gatattcttc gtattgtatt tcatctacta tgtactgacg acatggttat
    25261 atactggaat cgtattgaaa aagagattgt gaaaaagctg tcctgcatca agtaataaga
    25321 acagccaagc aaaaatagct cctcatattt ttcgtttggt tgggcttatt accgcagatg
    25381 caagcttttg aacaccgttt gttcggaaaa agaggttgtg acaatatttt tgtcacaacc
    25441 tttttttcac ggtcttttat tagaatatag taaatttttt ctcgttactc acggaataag
    25501 ctgttaagaa aacggtttcc atgtatactg gaatcagtgc aaatgaaaga aaagagggtg
    25561 caaggaacat ggaaatcaat gaacaaaatt ttggcgaaaa ctatcacttg attacgatca
    25621 cgaatcaaaa tgggacatct ttgtctgtca gtgatcttgg ggcacgggtt gttcattttc
    25681 aaacaataat cgataatgaa aaacgagagt tgatcttagg ttttgatgaa gcaaaagaat
    25741 atctagaaaa agacccttat atcggtgctt caatcggacg tatggctgga cggattacga
    25801 atggcacatt caaattagat gatgaaacgt tcgaagtaaa aacagacccg gacactggtc
    25861 attgtttaca tggtggtgca cctagctttg aagccaagca gtggcattat acagtcatca
    25921 atggtgaaaa cgaagcatcg gtcattttct atcagactag cccagatatg gaaaacggat
    25981 ttcctggaac tttagatgta gaagtacggt atacgctgac gaacgatgat acatggcgag
    26041 tgacggtcca agggatcagt gaccgcaaaa cagtattcaa tcctacaaat catgtctatt
    26101 tcaatttaac cggtgatcca gcacagtcaa tcgacgaaca tatactttgg ttgaatagcc
    26161 gattatttgc tacgctcaat aaagatacaa cgcctacagg agaagtagtt tcagtaagtg
    26221 gcacagcatt tgacttccaa cgtcctaaaa aattaggtga ggtctttgcc agtgattttc
    26281 gccaatcaat gatagtgggc ggcatcgatc atccattttt gttgaaaaaa caatctggtt
    26341 tactaaatgc tgcggaattg acaagcccag atgaaaaagt atcgatccaa gtaaaaacag
    26401 atgcttcagg aatcgtgatt tttacagcaa attttggaga agatggaccg gaaatgcgcg
    26461 ggaataaatt agtaaatcat ggcggtatca catttgagac tcaagaactg ccaggagcgg
    26521 agcgacttga aagttttgga gatgtcactc tggaacctaa ccaagtacgc gagtttgtaa
    26581 cggaatacaa aataaatata aagaaataga ataaattaaa aagggagtgt gacagtgtca
    26641 catccccttt ttaatttatt ctatttcttt aaaggcagat caagccagaa tgatttgtct
    26701 aaacttaaca aggttagtac aggaacagtt gcagctttaa ctgtacgagt agttgtttct
    26761 ggtatctgtc ttgccgtaaa attgttccac aaatcccaga ttgaagcgac acggaagatg
    26821 gaagaagcgt tgttgacgcg ttttatcgtt gaaaattcta atcctgtgat tggcacgcca
    26881 tctgttgtcc atttgattgg cacatcgaat cgcttagaca tattgaggat ttcagcgttt
    26941 gcttcttcag ttgttgctgc ttcttttttc ggttcatcat attttgtcag gtcgtacgct
    27001 tcgatgatcg cgttcaattt ttgtgaatat tggcgatctg tagcataacg tccttccaaa
    27061 tatttggttg cttctttgta gtcttttgtt tccgacttcc aagttggttt gtagaaatca
    27121 ggattgccag tcagtccatt tttgatcaag tcggcatagt cttccaaact ttccttgtaa
    27181 gaaggatatt tacggaattg tgcgcggatt tggtagcttt gtccggaact atcttgttca
    27241 agtgtattga aggtcacgct gcttccttta tatgatcctt tgataccaaa aaggttatga
    27301 tttggttcgc ttgataataa gctgtttcca gatccacttt caaggatagc ttgagccatc
    27361 atgactgatg cgtagattcc ttctttttgc ccgatttcct gtgcatcatc tgcaatcttt
    27421 ttcaagaact gatcagttgt ttggttttga ctgaaatgga acgagccatc taatccatct
    27481 aaaatagatg agccgcctgt cagcgaacct gaagcagcag gtaaacctgc taagtttact
    27541 cggacagcaa aatcaggcgt gaaatctgaa atagaagtta ctcgaacttt atctcctggt
    27601 tgaggcgcat ggataaattg tccgttccca atatagatac ctacatggtg agtaacaccg
    27661 gaagaaggtc cccagaagac gaggtcgcca ggttgggcct gacttactgg aatctgcgta
    27721 cctgcatatt gctgttcgcc tgtccagcca ccgatataat gaccggttgc tttcatatat
    27781 acgtaataag tcaaaccaga acagtcaaaa gtatttggac cttttgctcc ccatacatat
    27841 ggttttccaa gatgcttgaa tgcttctcga acgattgctt gttggacatt cgttgtattt
    27901 gtaggcaata cagcatcaat tggtgatttt acaacaaaat cagaagaagc agaagatgga
    27961 ttctctatac cgctttgatt tgctgtattt ggacgagatg aagcattgtt cgttccgcca
    28021 ttcgatgaac cattgtttgg atggtttggt tctctctgag tatttccatt gttattcgat
    28081 ccagatgggt ttgtttgatt cgaagaattc ccgctgttcg aattattgtt attattgttt
    28141 gaattatttg aaccattatt attgttgtta ttacccacat ctggtttgtt tggcgtttcc
    28201 ggatctggtg tactagggac ttcttcacta ggatcagttg gtttctctgt tgaagtatcc
    28261 ggtccagctt taaattctgc agtaatagat aaattgttcg tacctactgt aaaggtcttt
    28321 gcatcataat ttacttcttt ggcaccatta acagcgactg aagcaatttg ttcaccttca
    28381 gctggcgtaa tagtgtaagt taccttcgtt tccgctaata aaccttctac cgttccactt
    28441 tccgtaatat ccaaaggttg ctgttcaggg gaatccgctg tcgaagcagt cagttggatc
    28501 ttaccaatca aagaaggagc aattgtaagg gaatatgtct cggctggctt ttcattttct
    28561 gatggatcag ccggatcaat ttcagttggc tcggtcgatc ctgttgttga gttagttgtt
    28621 ccagttgggt cttctgtaaa agaatccgtt gtttcactag tagctgagct ggatgtagtc
    28681 gtatctgttg tgactgtttg atcagctatt tgattatcta cggcaaatac ggtattggtc
    28741 gacaaaacag acggagcaat cagccaagta gcagctagca aacgtatcgt ttttttattt
    28801 ttcataataa actagtcctt ttcctttcat tgattttctg tcttattcag cattcattag
    28861 acattttttg gaacagataa tcgtgtcgaa aagctttttc ttttcataaa tctgtctgtg
    28921 tattctaaat aaaacaattt gtaaataagc aacgagcatt cattcgtttt tctttgacgt
    28981 tcattttatt gcatagacca cctttgtttg gggataaaca agtggggata aaaatggtta
    29041 tgcatatgta aattatacca aagtttggaa agtatcacaa aaatttataa aaataatgat
    29101 cctaaaaaga aaaagactga aatatgtgat aaacatctca tacttcagtc tttttcatta
    29161 actattcata agacattagg tcttcatcaa acccgctaac gagagtagtg atcattgcta
    29221 cgactagact aacagccagt cctgctaagt accagaaaaa agtaccggaa atgaatgcag
    29281 gcaatgtggt cagactacca aatacaaaag cgatcgcttt cacttgggca aatcccatta
    29341 cagctccacc agcagctgca ccaatgcaag cagcaacaaa tggttttttc aatgggatcg
    29401 caattccgta aacagttggt tcggtcactc ccgcaagtaa aatcgaagca aaagcagaac
    29461 cggagatcga acgggttttt gaacgtttac ttcgcagaaa tacacctaaa gctgcaccag
    29521 ccattccaaa attggctgct cctgtcaacg gaacgattcg gtcgaaccca taagcagaga
    29581 tattactgat catgacaggg tttacagccc attggatacc aaatattacc aaaatattcc
    29641 aaccaccagc gatgattgcg ccactgatcg gtccgttaat atccatcatc caagtaattg
    29701 cggcagctaa accttcgcca aggtaaacac ccgcaggccc gaataccatt aacgtcaaag
    29761 gaaccgtgat aactaatgaa agtaaaggta caaatactaa ttgcatattt tcgcgaatat
    29821 attttttgag gaatttttca acaaaagaat aaaagaaaat acctaaaatc gccggcatga
    29881 cagtagacgt atactgcatc agtactacag gaatccccag aaaatcagta gctgctttgc
    29941 cactgtctga aagtaaagag gtcagattcg gttcaatcag tgctgcagca atgacagccg
    30001 caatatatcc attcacttta aacgttttgg cagcagaaaa agcaagaaag attggcagaa
    30061 aataaaagac ggcattcgac gcagcagaca aaatatgata agttccgctt gtttcactaa
    30121 gccagccaat cgtagtcgct aaaacaacca gaccttttaa tataccagaa ccggcaaaca
    30181 gcggaatgat cggcgtaaag atttccgata tcaaaccaaa tagtttttcg atcggattta
    30241 gcttttcttt cggagctgaa tgatcgattt gacgcgtcaa ttccttgtaa gcaggagcca
    30301 atccctgatc catgattatt tctgcatatc tatcgagtaa aatgaaatac ttaatggaag
    30361 ggatttgctg ttttaatttt tctgcattgg ctactggctg ttttttcaat ttgatacgaa
    30421 gccgagtcgc acatggaagg acagaatcaa tattgtcttt tcctcccaac tgttcaatca
    30481 gcatatgaat ctgctcggac agtaccatct gttcaggatt cattgtcgtt tccattagaa
    30541 gaccactcca ctcactaata taatattggc gtaaggtgtc atttcgcctg tacgaataaa
    30601 tgcatgacag ttattcaact cttttttcat ttcttcatgt gggataaagc taatcggtgt
    30661 atctggtaac aataatttga ttttttccaa tatttccggg ttcattgtct ttatttcttc
    30721 cgccaattca atcgattgta cctcaagttc ttctaaaacg ttttctaaaa cagataaaaa
    30781 acttggaaga ccgtttgaga cagccaaatc tattttttca gtaccaaagg ggacaggcat
    30841 gcctgcatcc ccgatactta atttatcaaa gtgccccatt tgtgcgatta ctcgtgaaat
    30901 atctgaattg attacttttc cttttttcat gtttgtttct tcctctcatt gttaatttta
    30961 gactgctgat tgttctaaag cttcgcggta agggatagaa ggttgcgcac cataagactg
    31021 cacagcaaca gaagaggcta gatttccata aaggatcgct tctttcaagt tactaaggtc
    31081 tggctgaagt gtgctgctta atgcgccaat aaatgtatca cctgcggctg ttgtgtcaac
    31141 ggcatccact ttaaaagcag ggacgatacc gtgttctttt tctgtatgat agaaagcgcc
    31201 ggcactgcct agtgtaatga ttactgttcc aatacctaat tcatggagtt tttcggctgc
    31261 tgcgaccaaa ctgttatgat ctgtcactct gattcctgta atgatttctg tttctgtttc
    31321 atttggtata atgatatctg tcttttcaag tagttcagta ggaatcgttt cacgagctgg
    31381 tgcaggattc aggatcgttg tttttcctgc gtcttttgca atagaaaaag ctaggatcgt
    31441 cgcatctaag ctactttcaa actgagcaat aataaagtca ctgtttgtaa tcagttgctt
    31501 gttttttagg acttcttgtt catggaaagc attatttgcc cctgcatgga tcaagatact
    31561 attttctcct gctgcgtcta ccataatcat tgcttgtccg gttgtggcgc cttggatttc
    31621 agctatccca gatgtatcga tgttttcttt tgtcagtaga tctaataact gttgtccttc
    31681 gctgtcagcc ccaacgcctc caataaaaga tgtccgtgcg cctgaacgtt tggctgccac
    31741 tgcttggttg gcacctttac ctccgccagc gtgaaaaatc tcatgcgcat gcatcgtttc
    31801 gcctggcttg ggcatgttgg ttaaacgaag ggtagtgtcc atattaatac ttccaattac
    31861 tgtaaccgtg ttcattttac aaacctccaa ctatctcatt tattttgatg ggaaaattat
    31921 tttttaaaac gttttagtaa aacgttttaa tagttcgata aaaatatagc acaccttgaa
    31981 agctatttca agggtgcagt tgaaaatctt ttttctaatc gtacaggtaa tcttttttct
    32041 tcccattctt tttctgggaa ttggatccga tctaacaata acttggcaga tgtttgtccc
    32101 aattcgaaga ttggttgtgc gatcgttgtc agtttcggct tgatatactc gcacatatct
    32161 atattatcat agccaataat gctgtagtct tcagggatgc tttttccagc ttcctctaat
    32221 ccgcgatata atccaaaagc taattcatca tttaaagcaa acacaccagt tgcagcagaa
    32281 tcaagaagtt ctgctgtgat ctggtagcca ccttgttttg agaactgtgt aggtaagagg
    32341 atcagttggt cgtgagggat ttggtaaaca tcaagagcag atttaaaccc ctcaatccga
    32401 gcgtggacat tttccggtgg attttcagga tagacaaggg cgatcgtttg atgtcctaga
    32461 ctaagcaagt gcatgcccgc taggtaacca ccgcgaaaat cgtctgttcg tacggcatca
    32521 ctaaatcctt cagatttttt ctgatccaaa acaatgaagg gccggccttg ttttttcaaa
    32581 ttttcgttga ttgcatctgt agagacagca gaagtcgcga taatgaatcc atccacacct
    32641 cgacgtgtga gctcggctag atattcgatt tctttttgat gatcagaatc agcattacat
    32701 aatatcgtga cgaaattctg cttatacaag atatcctcaa ttcctcgcat cagtgtactg
    32761 aagaatggat tcgtgatatc aggaacgagt acaccaattg ttttcgtttc cttggtaatc
    32821 atttgtctag caaaatagtc aggctgatag cctaattctt ctttggcagc taaaactttc
    32881 tgaacagttt tcggactgaa tttctccgta tttccattta atatcaagga gacagttgtg
    32941 attgaaacgc cggaaagttt agcgacttct ttgattgtga tctttttttt caccatgttc
    33001 atactcctat ctaaatcctg tggttatttt cccatgaaat caaaaagaag taaatgaaaa
    33061 tcacgtgtgc cagtacttat ttgctttgtt ggatagcttc gattatttgt ttcgttgagc
    33121 gtactcgtgc agttttcgga aatatctttt ttatgaacaa ttgatgggat tctttgtcac
    33181 gatcactgca agcatcttca gcaagcacga tatggtaccc gtgttgaaag gcatctaatg
    33241 cagtagcata tacaccgttt gttgtcgcta caccgcttaa aatgatagtt tcgattccac
    33301 gccggcgaag ttgaagatca agagaagtac caaaaaaagc acttggattg tattttgtga
    33361 tagtcaacat attatctgta tctttcaaag aatccttcaa aagtaaatca gtgaattctg
    33421 gaggtacaga agcagtcatt ccacccatat cagtttgttg actcaaataa gggaaagtgg
    33481 agatgtctac gttcactaaa actttcaagg cagcggtacg tttcaatgtt cttactaaca
    33541 aatcattgtt tgtcagaata gatgctgcag tgtgtggaga gagtgtaccg ttatttacga
    33601 tctctttttg catgtcgatc gcgacaaaag cagtttttga taaatcaaaa atcatatttt
    33661 cctttaaatc attcatgatg ttccttcttt caaataacaa tgttttttat gtaagtaaat
    33721 cataaatcgt ttatttgtca actaaattaa aggattcctt tctttagtct agagaaattc
    33781 agtggtaaaa taaataagtg tgagaaaacg cattcgatgc atagatatag cgagaaatat
    33841 cgtgaaaatg gaggaatcag agtgaagtat gtcgaagtaa aaaatgaata caaacgatac
    33901 aaaatgggag aaacgaccat tacagcaaat gacgatattt ctttttcaat tgaaaaaggc
    33961 gaattagtga ttatacttgg tccaagtgga gcaggaaagt caacgattct taatatttta
    34021 ggtgggatgg atacacctga tgaaggtcag atcattattg atgacacaga tattgcgcaa
    34081 ttttcagata aacagcttac tgcttaccga cgaacagatg tagggttcgt tttccaattc
    34141 tacaatctcg ttcctaatct aacagcaaaa gaaaatgtgg aattggcaac ggaagtttct
    34201 cctgatgcgc ttgatcctgt agaggtattg aggcaagtgg gcctagctca tcgattgaat
    34261 aactttccgt cccaattatc aggaggcgaa cagcagaggg tttcaattgc tcgtgcacta
    34321 gctaaaaatc ccaaacttct tttatgtgat gaaccgacag gcgcgctgga ttttgaaacg
    34381 ggcaagcaag tattgaaatt attgcaaaac gctagcagac aacacggcaa taccgttttg
    34441 atcattacac ataattctgc tttagcgccc atcgctgata gagtcattca cattaatgat
    34501 gctaaagtaa ggtctgttga attaaatgat catccttcat ccattgatga gattgtatgg
    34561 tagggggatt ttatgaaaac aagaacatat cttaaagcag gttttcgcga aattcggcaa
    34621 tctaaaggac gattcattgc aatcatcctt attgtcatgc taggaacact tttatttgta
    34681 ggtgtcaaaa ctgctggacc tgtcatgcaa aaaacgatgg atcactatgt tggtacagca
    34741 ggactttctg atttgcaaat cgtttctact ggtggcttga cacaaaaaga tattgctcaa
    34801 gcagaaaaga tcccagatgc aaaagtagaa acaggaaaac agatctatta ttccaatact
    34861 ggcaaaaacg aagtgattca aatattttct tataacaaaa ataacaagca gaacaagcta
    34921 caattaactg atggaaaact cccggaaaaa ccaaaccagc ttgtattgga tgaaaaagcg
    34981 gaagatgaag ggtataaaat cggtgatatt tatcagattg attcagatga attgaaagaa
    35041 aaagagtata ccatcacggg ctttgtccgt tctccattgt tcatcaacaa tttggagaga
    35101 ggatacgcga acgtcggaaa tggtagcgtc gattattttg tctatttacc tgaatccgtt
    35161 tttaaaacag atatttattc tgtcttatat cttgatttta caaacgtaaa gaatttgaat
    35221 acgtacagca aagcttacaa agataaaatg gagcaaaatc aagaaaaggc agaaaagtat
    35281 ttacaagatc gacccgaaga acgcttagaa gagctgaaaa aatcggccaa cgaagaatta
    35341 gaaccggcac agcaaaaaat agcggatggc aaagcacaaa caacgcaagc aagaacacgg
    35401 ttagaagatg ctaaaaaaca gttagcgcaa cagtcagcaa ctatccagca gcttcctgaa
    35461 gcgcaacgaa caatcgctgt tcaaacatta tctcaacaag aagctcaact tgctgaacaa
    35521 gaaaggcaat tagttgagaa agaacgtgaa ctggcctctg cagaggaaga attgaatcga
    35581 aatgcagaaa aaattgaaaa tttaactaaa ccatcatacc tatacaatga acgttcagaa
    35641 aatgtcggtt ttcaagaatt tggtgatctg tctgatcgta tcgctgcgat tgccaatgtt
    35701 tttcctgttt tctttttctt tattgccgca ttgatcacct ttacgacaat gacacgtatg
    35761 gtagaagaaa accgcaggga aatcgggaca ttaaaggcgt taggttatac gaaagttgaa
    35821 atcgcaaaaa aatatgcaat ctatgcaagt ctagcctcag ggataggtat tgttttagga
    35881 acgatattag gaacgaatct tttgccaagg atcatttttg agctgtctaa cgagcggtat
    35941 gatattggga gtgcgcttat tttttatgac tggccgccga ttttacaagc agctgccgca
    36001 ttcttcattg ccgcatttgg cgctgcaatg atcgttttat tcaaagattt aagagaacgg
    36061 cctgctgcat tgcttcaacc gaaagcaccg aagccaggga aacgcatttt tcttgaatac
    36121 atcactccgc tgtggtcacg ccttagcttt aatcaaaaaa tcagttaccg aaatctcttc
    36181 cgatataagt caagaatgct tatggcgatt atcggaattg ctggatgtgc cgggctgatg
    36241 gttgcaggcg tgggattgaa agattctcta agttctgttt cagccaaaca atttggaccg
    36301 atcattgact atcaagcaat cgttacattg gattcatcca cggaagatag tcgtcaaaaa
    36361 gcagcggata tgctgcagaa gcaagaaaaa gtaaatgaga tcctagctat tcatactcaa
    36421 accgtagaat tgagaaaaaa aggacatgct tcgcaaagtc tgacagtgat cgtaccaagt
    36481 aaaacagctg atttggatcg ttttatccat ttaactgatc ttgaagagaa cccacgctcc
    36541 ttgcctaaaa caggaatcgc tattacgcaa aaagtagcag aactatttga cttatctaca
    36601 ggagatcata tttcgcttta tgatgaagat caaaaagaat ggaaagtcga agtaaaagaa
    36661 atcgtgaaaa actatctagg tagctttatt tatatgtccc ctgaatatta tgcttcagtt
    36721 actgatcaat cgatgatgga taatgcattt ttgctgcgta cagataagat gacaacaaaa
    36781 gaagaagaaa tgctttccga gaaactgctt gccacagacg ctgtgacaaa tacgtctttc
    36841 atgtccaaac aaatcgaaac gcaagaagaa tcaatggcga acttagactc ggttgtctta
    36901 atctttgtcg tattatcagg actgctggct tttatcgtct tgtataatct aactaatatc
    36961 aatatttccg agcgtgtacg cgaattatct acaataaaag tccttggatt ttttgataaa
    37021 gaagtcacga tgtacattgt tcgagaaaat atcatcttta ctcttttagg aatcatcgga
    37081 ggatttggtg taggatatat attgactgac ttcatcttgc aacaagcgtc tatggagaat
    37141 gtcatctttc cattagtgat cacatggtgg gcttatgtct tatcagcagg attaactatc
    37201 gtatttacgg ttattgtgat gattgttacc catttcaaat taaagcatat cgatatgatt
    37261 gatgcgttga aatcgaatga ataaaaacag aggttgtgaa atcagcggtt tgacctgagt
    37321 attagagaaa caaacggcaa aatagttttt catattttgc cgttttttga gctaataccg
    37381 aaggacagct gattgaacac catgaatcag aggttgtaaa aaagccgtcc tgcatcgagc
    37441 aaaaagaata ctcaaataaa attagctcct catgttttac atttgagaag actgattgcc
    37501 gtagataaaa gcttttgaac accatttata gaagaaacaa gaatattttg ctattttaaa
    37561 caagaggata gacaaataca tgtctgatct cttgtttttt attgggcaac agacctctta
    37621 gaatgtataa agataaattt tacaaacgct ttcggttcag ttataataat aaatgataac
    37681 ttgtatatat aagttgtggt aggtaataaa tcagttgaat ggaggtaaat atccatgaca
    37741 tttaaagaca aagtcattta ccaaatctat cccaaatctt acaaagacag taatggtgat
    37801 ggaattggag atttaaaagg aatcaaagaa aaactcccgt atctgaatga tctaggcatc
    37861 gacatgattt ggctaaaccc tatttatcca agccctcaaa aagacaacgg ttatgatatc
    37921 tctgattaca cagccatcga tcctatcttt ggtacgatgg aggaattcga acagctaata
    37981 gccgaagcaa agaaataccg gatagaaatc atgctcgata tggtgctgaa tcacgtttcg
    38041 acagaacatg aatggttcaa aaaagcacta gcaggggacc agcattatca ggacttcttc
    38101 attttaagag aagagccaac ggattgggta tcaaaatttg gtggaagtgc ttggtcgcca
    38161 tttggagata cggggaaata ttatttgcac ttatatgatc ggacacaagc tgacttgaac
    38221 tggcggaacc aagcagtaag agaggaacta ttcaaagttg ttcgtttttg gatggaaaaa
    38281 ggggtaaaag gattccgttt cgatgttatc aatgttatcg gtaaagacga acaattgaaa
    38341 aataataaag aaaatgatgg caaacctgaa tatacggaca aaccaatcac ccatacgtat
    38401 ctaaaagaat tgaaccaagc aacgtttggg acggattcca ctatcatcac agtcggtgaa
    38461 atgagctcta cgacgatcga aaattgtatc ttgtatacag aacctagtag agaagaatta
    38521 tcaatggtct ttaatttcca tcatttgaaa gtcgattatg aaaatgggaa taaatggtct
    38581 actcctccat ttgattttgc agaattaaag cgactatttc atacatgggg agaaaagatg
    38641 agtgagggta acggctggaa tgctctattt tttaataatc atgatcagcc acgtgcgctc
    38701 aatcgatttg tagctatcga tcagtatcga aaacaaggag cagagatgct agcaaccatg
    38761 atccatttga accgtgggac gccctatatt tatatgggag aagaaatcgg catgatcgac
    38821 ccagactatt catcgatttc cgactatatt gacgtagaaa gtttgaatgc ttataagtta
    38881 ctccttgaac aaggattcac agaaaaagaa gcgtttcgtc ggatcaaagc aaaatctcgc
    38941 gataactctc gaacacccat gcaatggtca gacacagaac aagcaggatt tactacaggg
    39001 aaaccttggt taaaagttgg aggcaagcta gaagagatta atgtagaaaa agaactatct
    39061 tctgaagatt ctattttgtc ctattacaag aaattgattc ggctgagaaa aacatatcca
    39121 atcgttgcac aaggagatta tcatgcttat gaagcaaatc atccggaagt ttatggcttt
    39181 cttcgccaat ttgaaggaca gcagctgctt gtattaacaa atttctatga taaagataca
    39241 aggatcgcca tcccagaagg attcacagaa gccaatattc ttatcgataa ttattccgat
    39301 actgttcttc atcaaagtct ggagctaaaa ccataccagg caattgcttt gctgaaaaat
    39361 taaaacaaaa acacaaaacg tcgttcctac gagctattct cgtaagatcg acgttttgtg
    39421 ttttatttaa aataatcttc ttcagaaaat gaagagtttt catactctcc tttatcgcca
    39481 taaaatttat tgtagcgttg tttgaattta cggaaaataa aagtaacgag taatttgact
    39541 aacgtataga taggaatacc aaaaataacg cccacaattc ccattagatc acccatgaca
    39601 agtaaaacga ttaagatcgt aatcggatgg atctgtaaac gatcacccat tactcgagga
    39661 atcaccaagt caccgtggag aagttgtacg gcaaaccaga caatgacaaa tttgacagcc
    39721 ataaaagtag agtcttggaa tgcaatgatc aaacctggaa agaaggcgat aaacggccca
    39781 atatatggaa tgatacataa caacccagca gaaatagcta aaacactagc aaattctaat
    39841 ccgatcagta agaaacaaac ccagtagact gctccaagga taaatgaagc aatgatttgc
    39901 ccctttagaa atgaacccaa ttgttgatta gcaatctttg tcaaattttt aaaatctgta
    39961 cgaaatgctg gtgggacaat cgctaaaact gactgataaa atttttgagg atctctcaaa
    40021 aggaaaaaag cgacaattgg accagtaaat aaagtaataa aaatagctgt aacagttgaa
    40081 aaaatgttgc tgatccgttg tgcgccactt tcccaataat ttccaataaa tccagctata
    40141 tcagacgtca cgtcgtcaat agaagcgaaa aattgattaa atgaatcggc aaaaggtgtt
    40201 ttctccaaaa attgtcggag actctcttga aaatcttgaa acaaatctgg caaactactg
    40261 atcaatgtct ttgcctgttc ttcaagaaaa ggaataagcc atatgcttcc aagccccaat
    40321 aaaaataaaa taatcacata aacgataatg actgacaagt tcctcgaaag gtgcttgctc
    40381 aaacgtttga tgactggttc caaaagataa tacaagatca gtgcaaacaa taatgggggc
    40441 aagatagtag cgataatgat tccgacaggc ttgaatataa acgagatctg atggaaaaaa
    40501 taaatgatca gcgcaagtaa gataactatt cctaaaacat agtaagaggt ttttcctcct
    40561 aaaaagcgga tcaaacgatt cgttgtatct gtttcttttt tcactctttt tcctccttta
    40621 tctataactt cattatagac aaaagcgggt ataaaaggaa aatgatagag gttgattgca
    40681 aaaatatcgt caatcattca tataaacttt ctcatcaatt aaaataagaa aacgcttgac
    40741 agttctttta accatatgat aaattaaatc ctgttgctaa aacgtaacta ttacggtttg
    40801 cgaaaagcga atcggaacat tcaaatgaaa gaagatgaga agaggagtgt cataaatgaa
    40861 acgattgata ggtatattgg ccatgctggt tttagcaggt atgttaactg cttgcggggc
    40921 aagtgggaaa gccgaggaca gtaaagaaaa attgagcgtg atgacgacct tttatcccat
    40981 gtatgatttt acaaaagcaa tcgtcgggga tgaaggagaa gtagagttat tgattccagc
    41041 agggactgat tcccacgatt atgaaccttc tgctaaagac atggcaaaga tccaagatac
    41101 agatatcttt gtttataatg atgaaaacat ggaaacatgg gtccccgcaa tccaaaaaac
    41161 attacaagaa ggcaatgtcc atacgataaa agcgacagaa ggtatgcttt tacttccggg
    41221 aagtgaagaa ggacatgatc atgaccatga acacggggaa gaaggccata cacatgagct
    41281 agacccacat gtatggctag ctccaagttt agcaatcaag caggtagcaa acatacgtga
    41341 tcagctgatt gaagcttacc cagaaaaaca ggaagtatgg acaaaaaatg cagcagccta
    41401 taccgagaaa cttcaagcac tccatcagct ttatcaagaa acctttaagc aagcaaaaca
    41461 aagatctttt gtcacgcaac atgctgcatt caactatcta gcgttagaat atggattgaa
    41521 tcaagtatcg attgctggtc tttcttctag tgaagaaccg tctgcggcga gaattgctga
    41581 actgaaacac tttgttaaag aacatggaat caactatatt tattttgaag aaaacgccaa
    41641 agatagtatt gccagaacgt tagcaaacga agcaggtgta tctttagaag tattgaatcc
    41701 tttggaagga ttgacgaatg aacaaataga aaatggagaa aactatcttt ctatcatgga
    41761 agcaaacctc gaagcgttga aaaaaacgac agagacagaa aacccgctag aagatacttt
    41821 gacccccaaa aaagaaaaga gcgtctacaa cggttatttt gaagacgagg atgtacaaga
    41881 tcgctctctt tcagattggg caggaacttg gcaaacagta gatacgtatg tagaagatgg
    41941 gacttttgat cctgtttttg aatataaaga aaaattgaat caggataaga cagcacaaga
    42001 atataaagaa tattatacga agggctatca aacagatatt gcttcaatca agatcagtga
    42061 gaaagagatg gcatttacgt ttaagaatgg aacaacgaaa cgttcaaatt atcgttatgt
    42121 agggaaagaa atcttgacct acgaggcagg aaaccgtggc gtaaggtatc tattcgaagc
    42181 agaagataag gaaagtggcg cttttagata tattcaattc agtgatcaca cgattgcacc
    42241 ggctgactcc gaacattttc atttatatgc aggaaatgaa agtcaagaag tattgctgaa
    42301 agaaatggag aattggccaa cattttatcc agatacaatg gatggacgtg aaattgcaca
    42361 ggaaatgctt ttgcactgat aggcaaaaaa gaaccgaagg gtttggatcg gctggtcatt
    42421 tagtcggtcc aaactattcg gttcttttta tgaaatcaat ttctttaatc cacggataga
    42481 ggctgggatg gtctcgccgt ttgccaacgt gacttctctg gtttttttat taatcgaccg
    42541 cacattttgt gtattgataa cataggattt atgacaacgg ataaaattcc gatgcatttt
    42601 ctcgatttct ttgatcttct catagaattg taattgggca tgagtcaaat ggacttccag
    42661 tttatgtggc gctcctagcg aagtagaaaa atattggatg tctttgatcg gtaaaaattt
    42721 gatctcatca ttaaactcta ttttgaagat atctttttgg atttgggaca tttgaaaatc
    42781 ttcgaaaatt ttgctcagga tatgctcgac attttctttt aaatcataaa gatcttcttt
    42841 gacgatataa tcagtcggtt cgatgttgct ttttaagatt ttcatcgaca tttccgtatg
    42901 ggaagtcaca tagattattt ttcctaaagg atctaattca cggatcaatt taccgatcgc
    42961 tacaccatcc atttcactgt cttctagttc gatatctaaa aagtaaatac caaaagaaga
    43021 agttctgatc ttggctgcat tgagaagttc ttccggatca gaggtagaaa tatggacata
    43081 actgtctaag ttttcaatca tgattctatt tttgatcacc gttgataaaa cttctaattg
    43141 ttttggatcg tcttcacaaa tataaatggg aatcatatca ttactccttt attttatttg
    43201 tatataaatc gtttgagaaa aacgctggtt ttcaattgat gtttcaagga aaagataagg
    43261 attggtcttt gtcaattcat ccaagataaa caagccaagg ccttcgtttt ttggatttgt
    43321 ttttgttgag aacccttttt gtttcaactg gtttaacggt aatgtatttg ttgttgtatt
    43381 gatcacacga atcatcacgg aatgattctt cttgagtatg gtcaattcga tttttttctt
    43441 ctttgcagca ctagctcctt caatcgcatt gtccaagata ataccaagca tacgtacaag
    43501 gtttaccgta tgtttcgtat ccagttcgat tggctcagga aaatgaagct ggacgatcaa
    43561 ccctttttcc tgtgccatca tgagttttaa tgacagtaaa ctacggatct caggaacttt
    43621 catattatcc aacatactta gattggccgg aaaaaggttc atcatctggc gtgtaggtaa
    43681 tatcgtttga tcataataag accgtaatcc ttctaagtcg ccttctgaaa tatagctgtg
    43741 aagagaaaaa agcagatttt ggtaatcatg tttgaattct ctcaagtctt gatagttttt
    43801 ttctagatct ttgatataat cctgttgcat cctgacttgt tgctctaata actgatcagc
    43861 taatttctta ttagagattt tccaataata aaccaagatg atcaggccaa cacacagata
    43921 tagaatgaaa aaactcgtat tcaaagctaa gacatcaggt gtttcaccag aaaaacgggt
    43981 ataaaaaata atgatatagt atgtaaataa tatcaatgtc ccgatcgtac cgatcatacg
    44041 gcggtccaca gtgtgaaacc aagtctctaa cgattttttt aaacaaaaag ctaataaagc
    44101 agataaaaaa gcggataaga caatgtgaaa atactgcaat gaatctcctg gttcaataac
    44161 cgaagatttc aaaacaaaaa aatcgccgat gcttgttaag tgatctccta aaagcgacgt
    44221 caataaccca aaaggaagcg cgtaaaccaa ttgttgacgc gaagtcgaaa agaagaaaaa
    44281 agtaagcatc agcattccta tagcaattag agcagtaaaa atccctaaaa tcgaatagac
    44341 ccatccaatc aaaatacaag aaatcagaat gactcccgca aacagatatt tgtatcggat
    44401 gtgatggtca atcaataaga tacaaattgt gtaaatcaaa tattgcaacg ctatggacca
    44461 taaaaacata aagtacagct cccattgatt tttaccaaat tatagcacaa ttggcgtatt
    44521 atttttttaa tttttcaggg attttgaatt cagaactcat accaaagcag cagccagata
    44581 caaaaaagtc agataagtta gttaattgtt taatgattgt ttttttcatg aaagattcct
    44641 ccaaaattca tcaagtagtt tgtaatagga agcaacgtag ctatttctaa aacaatccca
    44701 agtagcaaat aggtagaaaa gtaagaagct gagaaaaata acgtaatgag agaaaaaatt
    44761 agaaacatgc tgatcgcctt ctttaataat gggggacgtt tctcgggttc aatgggattg
    44821 attgctgtac ctcttgatcc atagcgaagc agtaacaaaa agcagctgat taacaaaaag
    44881 accatcattg ggaaggagat agtcaattgc agatgtttca tcaccaaggg aacgccccat
    44941 aaataaagta gtgtccacag cagacaaacg aattcagagt cggaatgcaa tccataagca
    45001 tatctgcgga tgcagatata agaaagaaag gtgattcctg tttccgccca tgagcctgtc
    45061 accagagaaa agactagaac gaccgctagt tttccaagat tattcaataa aacttctaag
    45121 acaaatttta cttggacata caccatatct tcttccgatt tgtctccgct gaataaggct
    45181 tctaataatt tgttcacaac tttatctttc atctcatacg tacctccacc acaaatttta
    45241 tgctaaaaaa aataaaaaac gtcttttgtt tcataaaaag tggttttgac atcaaaaccg
    45301 tcatgatctc ctaaaaaaat cttcgttttc caagaacctt accaaaaaaa gtgacagttt
    45361 tgatacgaaa agtacttttt atgacaagtt tgtgcttttt cgagtgattt atgttaaaaa
    45421 attactgacc ttataaaagg tgatggaggg attcttatgg aaaatgaaca attgtttgaa
    45481 gtcggcgaaa catatgcatt taaatctgat ttatttgaat caccaataaa aggaaaaata
    45541 gaaaaaatct atgaaaatag tgtgatgata cgtgtcatga aatgcgcagt agaagacaat
    45601 gataccgctc ataatctgca ctggcagtta gttgtacgca aatcaagtac aatagaagaa
    45661 taaaaacaga taaaatgttg agagcataaa gaggttgtga gtctcccgtt tagctctgag
    45721 ttacaaggaa taatgttaaa aaacagcttt tcatgtttta tgaatattgc cttgtgaccg
    45781 aggtgttggc aggagaatac tgtttatttg aaaaaagggc tgcgacaaga cttttgtcac
    45841 agcctttatt ttcatgaata ggagttactt ttggctactt ttagagaagt agcttttaag
    45901 gagcagataa agtcaaggct tttatttcta taaatgaagt agtaaaatga agaacagatt
    45961 ttattacagg aaggatgccg ataattgtga tcattgttgc aggaacgatc ggtgcaggga
    46021 aaagcacact aactgaaatg cttgcccaag atttagaaac aaaacctttt tatgagaacg
    46081 tggaagataa tgaagtattg ccgctatttt attctaatcc agaaaagtat acttttttat
    46141 tacagatttt ctttttgaac aaacgctttt tggcaatcaa agatgctttc agccatgatg
    46201 acaacgtact agaccgctcc atctacgaag atagtatgct gtttcatttg aatgcagatt
    46261 tagggcgtgt ttctgaagta gaagtaaagc agtatgaagg tcttttagaa acgatgctga
    46321 aggagttaga agaaatttcg ccacaaaaga aaccagatct actggtttat attcgtgtat
    46381 cctttgaaac tatgttagcg agaatcaaaa aaagaggccg ggaatatgaa cagctagaac
    46441 aagatcctga actctattcc tactataaag aactcaatcg acgatacgaa gagtggtatg
    46501 aacagtttga tatatgtccc aaaatagtga tcgatgggga caaatatgat ttcgtagccg
    46561 atccggcatg tggagaacaa atcgtacaag aaatcaagat gcgggcaaag aaaatgacag
    46621 aagaggcaga tgcccagtcg atccgctaca ctacaaataa cccgaaagca aagggaatct
    46681 ttacaactaa ataatataaa aactaagcaa attgctcact cgcagatatt tctctgtgag
    46741 cagcatcttg cttagttttt ttgattcatt gagatcaaat agtgaaccga ttcgtatgat
    46801 aaaattgcca taaatgaaat gtctgagtga gggccatgat caaaaataaa atggaaacga
    46861 tcaaaatcga atgggcgcca aacagatgat gacagaaaac aaggacaata gctcctgcga
    46921 taaaggcaag aacgacactt agatagtgga aaaatcgatc aaaatctgct ttttctttag
    46981 aaatacaata atcatataag ttcgttgcta ccccttttaa atttccagtt gtaaataaat
    47041 tagtgtaggc acgcccgttg attttatcaa aagctaccca ctggatcgat gcagtaaaag
    47101 caatcaaaat cgttactaat gcgggatgct catggacggg tgtcaaacta acaaagaaaa
    47161 aaatcactgc ttcataatat agaacaaaca agcgccagaa atgtttttct ttttttctaa
    47221 aataatcaat tagatacttt gttagaagaa tccctaagaa aaagaaaagg gtagacaata
    47281 cttttttacc aacacttagc cattctccgt caaatgcttg gatgatcgat agaatgatat
    47341 tgccagtttg agcagaggca aaagcaccat attggatata agtataactg tccatggctc
    47401 ctccgataaa tgtcagcaaa agtcctattg tacgcccctc gtgaaaggaa gtctgcattt
    47461 ttttcatcac cttttatgaa tatttttgtc ttccttatct tagcataaac gattgaaaaa
    47521 aaaggaaaaa ttttcagaaa actaaaatca tatcgcttcc cattttcatt tttagaaagg
    47581 tctgttagta taaagaaaaa atagacaacg aaactttaaa taaccaactt gaaataaaca
    47641 aattcaaaga agaaagatgg gaaggaaatc aatcagttga atgaaaaaga aattctccga
    47701 ttacaaaaag aattgaaacg ctgggagaac aagtataaaa agcttcaaca agtctttcgg
    47761 ctacaagaag aaatcattgc tacctatgaa gcggcttatg gcgaagcacc cggacttatt
    47821 gaggaagaag tacaagtaaa agaaagtgaa ggaaacagct ctttctttaa aatgatggag
    47881 aaacgttcct ataatcgctt caatcaagaa caaaaagcag ctatcacata tgatatgaag
    47941 aaacatcttc gaatcatagc aggagctggg agcggcaaaa cgcaaacaat ctgtgcaaaa
    48001 gctgtttatc tgatgacgca aaaacaagta gacgaagaac gcatactaat gatcactttt
    48061 acaaggaacg ctgcaaatga actaaaaaaa cgagtagata atttcagcca gagaaaaacc
    48121 gctgtccata tcggaacatt ccatagtatc ttttttagga tatacaatga aatttgtcga
    48181 aaatttcctg aagtagcaat gcaaggaata caaggagact tttcaaagga tactgcacaa
    48241 aaagtgaatg ctgttttgca acagctgata cgtaaatata atctttatat atttgatcaa
    48301 tatggagaaa aaacgattgc ttctcggtta gactattggc agaatatgaa cctttcagta
    48361 gaagaaatgg ttcagttagt taaagaaaaa tatgattcca ttgataagaa tgcacgacag
    48421 ccgatatcag aacgactgta tggattgctc acggaactcc aagaacaaaa aagaagccag
    48481 caattgctag agttcaatga tgtactccaa aatctgaaaa gcgctttgga gaatgaggag
    48541 atccagcatt atatcggcca aaaatatgat tatctattca ttgatgaatt tcaagatact
    48601 aatccacttc aatgggaaat cgtgaaacgg atgacaaagg aaaacaggat caagttgatt
    48661 gttgttggag atgatgatca gagtatctat ggattcagag gatcagagcc agcatacatc
    48721 aagaactttg aaaaagaata tcctaccaaa actcttttct tattaactaa ttatcgttct
    48781 cgggcagcta ttgtccaagg agcaaataga ttgatcagct ataataaaaa tgatcggata
    48841 ccaaaggcga tgattccagc acaaaaagaa gcaggtgtta tggaagccta tttgttttct
    48901 gatactaaag cagaaagtca gtggctaatc aaacaaattc agacatttat tcaaaaaaat
    48961 gggaaatata aggaatcaat catattatac cgatcagctt cacaaacgca gcagcttgtc
    49021 caatctctgc tgaaaacgaa tattcctttt gtactggaag cagatagtcc atatgaaggt
    49081 atctttggta tcaagtcttt ccaacatttc tatcaaaaaa ttgttcattg gcaaacagca
    49141 ctgaatctgc aaaagaaaaa tcaggcctac cagcaattgc tccggcagct gatggcagac
    49201 tgctacctga aaaaaagtga atgcgatcaa tacttttctc ctaaatatca aaatatagcc
    49261 gttgcagatt atattttgtc gataagcccc aatttaaaat cgaaatctgc agaaatccga
    49321 gagtttgagg aagcgttgcg taaaacagac cagcatcaag aaatctattc gcttgttcaa
    49381 agctatcttc atctgccacg tatagctaag gaaatcgacc agagtgatca agaatggata
    49441 cgagaagaag taaagcagca tgctactttc agaagactcc aagccttatc gcaagaaacc
    49501 caagcgacag ctaaagaatt aaaaacccgc ttgattgctt acagacaagg aaaacttgat
    49561 gcactatgta tccagagcat tcacaaaagt aaaggtctta gttaccgaaa tgtctttttg
    49621 attggttgta acgaaggaag tttgccttat aacggagcga cagaaaagaa agtaatcgac
    49681 tttaatgaaa taaaagcaga accagtaacg acgatagaag aagaacgaag actattttat
    49741 gttgcgatga ctagagcaag aaatcgtctg tatctatgtg tacctcaaat gaaaaattca
    49801 agaaaattga aagtatcgag atttatcaaa gaaaccggga gtcgtgtgaa aaaaggaaag
    49861 tgatagaaga gagggtgtga cagaagtggt cagtttcaag aaagaagaag gaatgtacga
    49921 aaattgcttc tcaaattttt gtgaaatttc agcttatttt cgaagaagct atttctggaa
    49981 cacagtttat tcggaaaagg gaggtgtgac aagaattttg tcacacctcc cttatttatt
    50041 ttgaaaatga gaatactatt atcaaaatag agaatatata gaaaaattct cattattcaa
    50101 acgtaaataa tcagttattt tgattttttt tatattttat tagctaataa ttggtatttt
    50161 aaaagaaatt actgtagaat tggattataa ttaaaaagga gtgagaaaat gataaaagta
    50221 tatacttcgc ctagctgtac ttcctgtaga aaagcaagag catggttgaa agcgaatcaa
    50281 cttgaatttg aagagaagaa tatttttgcc gaaccgttaa cagaaagtga gatcaaaaag
    50341 atcttggcag cgactgaagg aggagttcaa gatattattt ccactcggtc gaaaatttac
    50401 gaaaagctgg gcatagattt taacgaatta actttaaagc aaatgatcgt cttattcaaa
    50461 gaatatcctt cattattgag acgacctatt ttgattgatg aaaaaagaat actaatcgga
    50521 tttaatgaag atgagatccg gtcatttgtc cctcgtgaaa ttcgatgtgt tgccagaaat
    50581 ctgatctatt tacaaaacaa taacatctta aattcatagg gagggagcct tcgtggaagt
    50641 gaaagtctat ggatcagcgc actgtgtaac aagtctgaag gcgaaacaat ggttagaaca
    50701 ccatcaattg ccttatcaat ttgttgactt agaagaacgc gatttaagta cagaagaagc
    50761 agaagaatta tgcagttttg aagaagtgca agcagaacag ctatttgcga cttggtctga
    50821 ggcttttcac aacattgcga ttgacctttc ctgtgtagga aaaaaacaac tgattttttt
    50881 atgcacacaa cataccaatc tcctcagacg tcctttgatt attatcgatg aagttctatt
    50941 tattggatac aatgagcagt tgatggaaca gcttatctta aataaataga ctttaactgt
    51001 tttaatcaag tcactgagca tttcatacag ttgtaacagt cgaacactta gcatcaagcg
    51061 tgttatgtgt tctttttttg actttatttt tctactatag agacatgctc aatttatgtg
    51121 gtcaaaattc aaatctaggt ggggatatag agttaaaaat atattgacat gtgtaaattt
    51181 acatgatata ttcatttctg ttgttttaag tagcaaagca ataaaatagt attttaaaaa
    51241 acatataaaa tagttgttga catgttagaa atgacatgat aagataactg agttgttaaa
    51301 aaagaaccac ttgtgaagct tgattctatc gaaaaaaact tcaaaaaagt tcttgacaaa
    51361 taacaaatga taagttatga taaatgagtt gctgtaagat ttcgaaaaac gaaatcaaaa
    51421 aaacttttaa aaaagagttg acaattactt gtctctctga tatgatataa aagttgctac
    51481 ggcagccaaa aacgaatcgg ggaacactcc tgatgaagta gacctttgaa aactgaacaa
    51541 agtaagacaa accaaatgtg tagggcgtct tgattcaatt caagacaaca aaca
//
LOCUS       DADGHT010000007        51536 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.007, whole genome shotgun sequence.
ACCESSION   DADGHT010000007 DADGHT010000000
VERSION     DADGHT010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.007"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(334..942)
                     /locus_tag="JX887_000352"
     CDS             complement(334..942)
                     /locus_tag="JX887_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HAX1256368.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(948..1976)
                     /gene="vanB"
                     /locus_tag="JX887_000353"
     CDS             complement(948..1976)
                     /gene="vanB"
                     /locus_tag="JX887_000353"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HAX1256369.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGTFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            complement(1969..2940)
                     /locus_tag="JX887_000354"
     CDS             complement(1969..2940)
                     /locus_tag="JX887_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HAX1256370.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            complement(2937..3764)
                     /gene="vanW"
                     /locus_tag="JX887_000355"
     CDS             complement(2937..3764)
                     /gene="vanW"
                     /locus_tag="JX887_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HAX1256371.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGEPFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            complement(3782..4588)
                     /gene="vanY"
                     /locus_tag="JX887_000356"
     CDS             complement(3782..4588)
                     /gene="vanY"
                     /locus_tag="JX887_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-B/VanY-G family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HAX1256372.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGRR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            complement(4759..6102)
                     /gene="vanS"
                     /locus_tag="JX887_000357"
     CDS             complement(4759..6102)
                     /gene="vanS"
                     /locus_tag="JX887_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAX1256373.1"
                     /translation="MERKGIFIKVFSYTIIALLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQAQSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            complement(6105..6764)
                     /locus_tag="JX887_000358"
     CDS             complement(6105..6764)
                     /locus_tag="JX887_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HAX1256374.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            complement(7707..7892)
                     /locus_tag="JX887_000359"
     CDS             complement(7707..7892)
                     /locus_tag="JX887_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAX1256375.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            8037..8408
                     /locus_tag="JX887_000360"
     CDS             8037..8408
                     /locus_tag="JX887_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1256376.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            8666..8995
                     /locus_tag="JX887_000361"
     CDS             8666..8995
                     /locus_tag="JX887_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAX1256377.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            8956..10284
                     /locus_tag="JX887_000362"
     CDS             8956..10284
                     /locus_tag="JX887_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAX1256378.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            10281..10652
                     /locus_tag="JX887_000363"
     CDS             10281..10652
                     /locus_tag="JX887_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256379.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            10835..11071
                     /locus_tag="JX887_000364"
     CDS             10835..11071
                     /locus_tag="JX887_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1256380.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(11371..11574)
                     /locus_tag="JX887_000365"
     CDS             complement(11371..11574)
                     /locus_tag="JX887_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256381.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMLVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(11578..12522)
                     /locus_tag="JX887_000366"
     CDS             complement(11578..12522)
                     /locus_tag="JX887_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256382.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            complement(12523..16443)
                     /locus_tag="JX887_000367"
     CDS             complement(12523..16443)
                     /locus_tag="JX887_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HAX1256383.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKID
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            complement(16592..18673)
                     /gene="topB"
                     /locus_tag="JX887_000368"
     CDS             complement(16592..18673)
                     /gene="topB"
                     /locus_tag="JX887_000368"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAX1256384.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            complement(18670..19899)
                     /locus_tag="JX887_000369"
     CDS             complement(18670..19899)
                     /locus_tag="JX887_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HAX1256385.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            complement(19889..20140)
                     /locus_tag="JX887_000370"
     CDS             complement(19889..20140)
                     /locus_tag="JX887_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HAX1256386.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            complement(20163..22154)
                     /locus_tag="JX887_000371"
     CDS             complement(20163..22154)
                     /locus_tag="JX887_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006060479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HAX1256387.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            complement(22186..24585)
                     /locus_tag="JX887_000372"
     CDS             complement(22186..24585)
                     /locus_tag="JX887_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HAX1256388.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            complement(24515..24937)
                     /locus_tag="JX887_000373"
     CDS             complement(24515..24937)
                     /locus_tag="JX887_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HAX1256389.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            complement(24951..25493)
                     /locus_tag="JX887_000374"
     CDS             complement(24951..25493)
                     /locus_tag="JX887_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HAX1256390.1"
                     /translation="MLISTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVE
                     RLASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTR
                     GNAEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFAR
                     QKTPGWDVWGNEVECDLILT"
     gene            complement(25524..26387)
                     /locus_tag="JX887_000375"
     CDS             complement(25524..26387)
                     /locus_tag="JX887_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256391.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            complement(26479..26694)
                     /locus_tag="JX887_000376"
     CDS             complement(26479..26694)
                     /locus_tag="JX887_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002574004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer protein"
                     /protein_id="HAX1256392.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            complement(26771..28579)
                     /locus_tag="JX887_000377"
     CDS             complement(26771..28579)
                     /locus_tag="JX887_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003819036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAX1256393.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            complement(28576..29052)
                     /locus_tag="JX887_000378"
     CDS             complement(28576..29052)
                     /locus_tag="JX887_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HAX1256394.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            complement(29127..29339)
                     /locus_tag="JX887_000379"
     CDS             complement(29127..29339)
                     /locus_tag="JX887_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAX1256395.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            complement(29361..30560)
                     /locus_tag="JX887_000380"
     CDS             complement(29361..30560)
                     /locus_tag="JX887_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1256396.1"
                     /translation="MLFTSGPDRAFERLMQEKPGFDHYDGGGADAPEDCGTCRFYRPD
                     WKYQFCQFAECPYQPGKLTDYAAVKFTVKGANNAMAVFRVEKNKGYTVMSNHHLRNKN
                     LTLKAKGLLSQMLSLPEDWDYTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDA
                     KGKMADMVYTIYEQPVLENPVLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLS
                     KKEKIITDGQSTHSIPIPSPTPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEY
                     AYLIQDRSIDREQLDEIVDLMLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRF
                     VLDCLRENTTKVRNIKQYLRAMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYS
                     CGEGESL"
     gene            complement(30817..31338)
                     /locus_tag="JX887_000381"
                     /pseudo
     CDS             complement(30817..31338)
                     /locus_tag="JX887_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
     gene            complement(31354..32052)
                     /locus_tag="JX887_000382"
     CDS             complement(31354..32052)
                     /locus_tag="JX887_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAX1256397.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(32009..33670)
                     /locus_tag="JX887_000383"
     CDS             complement(32009..33670)
                     /locus_tag="JX887_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAX1256398.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            33888..35288
                     /locus_tag="JX887_000384"
     CDS             33888..35288
                     /locus_tag="JX887_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAX1256399.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(35540..36619)
                     /locus_tag="JX887_000385"
     CDS             complement(35540..36619)
                     /locus_tag="JX887_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1256400.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(36705..37664)
                     /locus_tag="JX887_000386"
     CDS             complement(36705..37664)
                     /locus_tag="JX887_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAX1256401.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(37676..39199)
                     /locus_tag="JX887_000387"
     CDS             complement(37676..39199)
                     /locus_tag="JX887_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAX1256402.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(39209..39772)
                     /locus_tag="JX887_000388"
     CDS             complement(39209..39772)
                     /locus_tag="JX887_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAX1256403.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(39778..40641)
                     /locus_tag="JX887_000389"
     CDS             complement(39778..40641)
                     /locus_tag="JX887_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1256404.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(40655..41551)
                     /locus_tag="JX887_000390"
     CDS             complement(40655..41551)
                     /locus_tag="JX887_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1256405.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(41726..42997)
                     /locus_tag="JX887_000391"
     CDS             complement(41726..42997)
                     /locus_tag="JX887_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1256406.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(42987..44504)
                     /locus_tag="JX887_000392"
     CDS             complement(42987..44504)
                     /locus_tag="JX887_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAX1256407.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            44702..45592
                     /locus_tag="JX887_000393"
     CDS             44702..45592
                     /locus_tag="JX887_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAX1256408.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(45665..46489)
                     /gene="nadE"
                     /locus_tag="JX887_000394"
     CDS             complement(45665..46489)
                     /gene="nadE"
                     /locus_tag="JX887_000394"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAX1256409.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(46501..47973)
                     /locus_tag="JX887_000395"
     CDS             complement(46501..47973)
                     /locus_tag="JX887_000395"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAX1256410.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(48610..48972)
                     /locus_tag="JX887_000396"
     CDS             complement(48610..48972)
                     /locus_tag="JX887_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAX1256411.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            49195..49947
                     /locus_tag="JX887_000397"
     CDS             49195..49947
                     /locus_tag="JX887_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAX1256412.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(50087..51010)
                     /locus_tag="JX887_000398"
     CDS             complement(50087..51010)
                     /locus_tag="JX887_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAX1256413.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(51025..51297)
                     /locus_tag="JX887_000399"
     CDS             complement(51025..51297)
                     /locus_tag="JX887_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256414.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        12835 a        12717 c        11439 g        14545 t
ORIGIN      
        1 gaggggcaag gctttttttg agtggtggaa gtggattaga gcatggcaat agcaaaacag
       61 catagcggca tcctcctatg ggccgccaca ccttttgctg ccagaaaaga acggcggcct
      121 tgatttctca aaaccgccgc cagcaaaata caaaatgggc gtgggaaagg tctgcccaac
      181 agcggttttt ttcttttctg ccgctgggca gattgaatac tataatttgc aatgtattac
      241 aaaagatgct ttaaccactt tccagtaaaa gattgtccat gaccagcata gattttatca
      301 aatccaaaat ctgatacaaa accaatactt tcattatgaa acggcaaaat taaaataggt
      361 atcggggtat ggctcatcaa tcaacttata gtgccaccat tcaaagcgat aagactgaaa
      421 tccgctgctt tccatgattt tacgcaagca tcttcgattt tgtgcctctg catcccctat
      481 cccttttgct gtatgatgcg accgttcgtc cataaaatcg aagttacttc ccattgaaac
      541 aagttcccct gtatccaggt ggtagagcgt aagatcaatt gcgcttccac ggctatggct
      601 ggattgtgag gccacataac cctttgtaat caactcggct cgctctatat tggggtaaaa
      661 tttttctttt gtgagattgt cctccggttg cgctgcccaa cgcaggaagc agtccaccgc
      721 agttcttggc cgatatccat cccataaaag caagccatag ccaagcgcag ccgcatggat
      781 ttgtgcctcg cgcagagcaa acgccacggc ctttgtgccg atgatgcgat tcacctcata
      841 cccatccacc ggttttcctg tgaagttatc ccatgtggcg tacttggcat cccaacggac
      901 gccatgcaac atttcatcta aaaacaaaaa accattttcc atacttatca cctctttaac
      961 gccaatgtaa tcaggctgtc aatcagtgca ggaagcgtga ttcctgcggc ggccatcata
     1021 cgtgggtagc ggctgtacga tgtaaaaccg ggcagggtat tgacctcatt tagaacgatg
     1081 ccgccatcct cctgcaaaaa aagatcaaca cgggcaagcc ctctgcatcc aagcacccga
     1141 tatactttct ttgccgtttc ctgcacccga tttcgttcct cgaccggaat gtctgcggga
     1201 actgtaatca tcgcattttc tgagcctttt tccggctcgt tttcctgatg gatgcggaag
     1261 gtaccgtggc tcagccggat ttgatccact tcgccgacaa tcaaatcatc ctcgttcccc
     1321 atgaccgcac acccgacctc acagcccgaa atcgcttgct caattaagat ttttccatca
     1381 tattgtcctg ccgcttctat cgcagcgtta agttcttccg taccgtttac tttggttacg
     1441 ccaaaggacg aacctgaccg tgccggcttc acaaagacag ggtaggtaag cgcacccgcc
     1501 tccggcttgt cacctttatc aatcatttga aattcgggaa cggcgatgcc cgcatttttt
     1561 gtaagaatgt aggccagtga tttgtccatg caagctgcgg agctttgaat atcacagccc
     1621 acatagggga taccagacaa tacaaacagc ccctgtatcg caccatcctc cccgcatttg
     1681 ccatgcaaaa ccgggaaagc cacatcaata cgccgtgttt cgtattcgct ttctttcatg
     1741 acaagcagcc catgcgtttt cctatccggg gagagtatgg cggggagact gtcggcttcc
     1801 cattccgtac atggcttctt gcatagcttc catacaccgt tttttgtaat tccgatgtag
     1861 tgcggatcga atttttccgt atcaatgttc gcagcaattt ctattgcgga ttttaccgac
     1921 acatcatgtt cctccgagca accgccgaag atgattgcga cttttattct attcatgctg
     1981 taaactcctt tcaaaattga gacaattcct gattgttttt tctgtagtat cctgcagcac
     2041 acgctcagtg tagtacgccg tatggggtgt gatgatcaca ttcggcatcc ttaaaagctg
     2101 cgacaaaaag ggatggtcaa gcactttctg cgagcaatcg gtataaacaa actgatcctc
     2161 gccctccaac acatccagtg ccgcaccacc cagctttccg ctttccaacg cctccaccag
     2221 cgccccggta tcgacaagcg ctccgcgccc ggtgttgatt aaaaatgcgc cttgcttcat
     2281 ctctccaatt tgcttctgac cgatcagatg gcgggtatcc gcacaaagcg gcacatggag
     2341 cgtaacaata tcgctgtttt ttagaagctc atcaagctgg acataatctg catccatttt
     2401 tcggctgtta tcataggcca gcacatggca tccaaatccc cgcagccttt tgacgaccgc
     2461 ttgcccgata tggccggttc caataactcc cacagtcata tcccccagtt ctttcccccg
     2521 gatacgatcc aatctgaaat cttgttgcgc cacggcgtgc atggtgggtt ttgcaccccg
     2581 tatggccatc agcatcagca tcaaagcata atccgcaacg ctgtccggcg aatacgcaac
     2641 cgtgccaacc gagattccca ttctctcggc ggcagtcgta tcaatgtgat cgcagccgat
     2701 gctgcgggta gaaatgtatt ttaccccgac ctttctcagc gcaagaattg tcgcctcgga
     2761 aacctcggac ttatggccta cgctaacgca ttgattgcca gcggccaatt ttgcgttgtc
     2821 tgccgatatc gcatcgctaa tcagcgtagg gataatatga aaatccggcg ataaagcgcg
     2881 gaaagcattt gcctcatcct gttcgcatcc aaaaacagta atgcccacac tttttctcat
     2941 tggttctcct cctgaatatc cacactttcc gggaggggat aacagatttt gcatttgttt
     3001 gtataaagca gcttgcaatc tattatttcc ccggtaccta aggcaacttg catccgttta
     3061 acctgggcat attcataaat cccgccactt tcacggacat actggatact gccatttgta
     3121 attttgtata atgcttgggg ctctttgtcg gcggacacct gaccgatgat tttctcatca
     3181 tctaaggtca cccatatttg gtaggtgcag tcggtatcgt ttcgcacttt taaatcaatc
     3241 cagccctctg aaatggttgc atccacccct ttaatctcgt cactgtttgg ctctggaaac
     3301 tcctttactt cgtgacctct gcgctggata attgtcaatg gcgtatgcag gaacatccaa
     3361 aatagtaaat tgctcatctg gcacataccg ccgcccgaca tggtggtgag tttaccattg
     3421 gtcaccgtaa ggccgtcttt atagggggta tctttgtccg catggcgtac cagccaccag
     3481 aaagaaaagg gttcccccgg tcttatcaat aagccgttta aggtctttgc tgccagcttt
     3541 aagttgaaca ccttgttttc ctggtatatc atgtcaaatc cggtattgtg gttgtataat
     3601 gcgcaatccg tttcaaagag caaatgggaa agcgattttt cccctatcgt ctgcgcatag
     3661 cgacagccgt caaatctcat tcccgcataa aagcacattt ttctctgcgc ccgtctcatt
     3721 ggaagcagga acgggaaacg ctgtgtcaat ctttttctgt ccataacata acatcctttt
     3781 ctcatttttc tggttttaaa tattcctcaa ggcaaacccc ttggttgtac atctctgtgg
     3841 cagcttcgat gccaacatat cggtaatgcc acggctcgtt gctcacaccg gttatctctg
     3901 tcttgtctgg tgggtagcga cgaataaaac caaaacgata gctgttttca tccagccatc
     3961 tataaacctc gttgcctgtt gaatgaattc cgtccgcatt gatatccaca gcaagaccaa
     4021 gctgatgctc gctcgttccc ggcacggcca cccaagtttc tgcttccgct ttagcctgtg
     4081 cagaggtgta gcctttcgcc ttatattcgg caattttttc atccataatt tcttgctgtt
     4141 tttctgttgt tcggtatccg gatgcgacaa tcgggtaaac tccatcagtt cttgcggcat
     4201 caaacaaatc ttgaagatag ggagaaatcc gaatatctat ccgctcacca tttgatagtt
     4261 gctcaagctc cacatcgtac tgtgcgggga tggggttctg cctgttcact aaaatcaggc
     4321 tccattcctg ttcatctccc tgttctttgg cggtggcaag agcgttttcc tccaaattct
     4381 ccactacgtc agtgctgctg cctgtatgag ttgcagggat gggcggtatc tgtgttgcct
     4441 ccaatacgga agccagtctc cgccccaaaa acagcgtgca gactgtgaac gaaataatga
     4501 acgcacatag aaaagcccgc ttttccacgg attgtttcat atgccgtttg tgatgatccg
     4561 cattggaatg atagttgctt ttttccattt gatcgaatgc ctcctttgca ataaaactac
     4621 gatttgtggc tggtacgatt gttattatgg caagcgcatc tgtactttcc ctgtagccag
     4681 tctgtagttt tcctgtagca gcaaaaaaag accggcaggg ttatacctgt cggtcaaaat
     4741 catttaagtt ttaaatattt acaatgttga tgtgagcggt aaatccagcc agaacaaaac
     4801 gccatccgag gtgttttcca gcgcatactg gaggctcatg gcatccagcg ttttttgtac
     4861 gatggcaagt cctaaaccgc ttcgcccact ttttctgctt tgcgcctgat caatgcgata
     4921 gaatggggtg aacagccttg gaagcgcagt atcatcaatg tgaacgccca tgttcaaaac
     4981 aaaaaggcgg catttttcag caccaggctc actccatatc cgtacctcgc ctccctgcgg
     5041 cgtgttctga actgcattca atatgacatt ggatagtgcc ttttggagca gcctcggatc
     5101 ggacaggaca atttgcccgg ctggaatatc tgtgacgaac cgctggttgt ttgcctctgc
     5161 caaggtttga aaatcgggca gcaactcggc aaccgtgcgc cctatgtcca acggttcagc
     5221 tatgggtacg attctcccat cattcaggct gacaagctcc agtatttcgg aaatgatttt
     5281 gccctgccta tccatcattt tgatgcattc gcgcagatac ttagaatgat ctttgtagtc
     5341 accgatattt tcaagcattc cctccaacag aacgcttgta gccgcgatgg gcgtttttag
     5401 ctcatgagaa gctgccgcaa agaaatatcg ctgtgtttcc tccaactcat gttcccttgc
     5461 gatttcatcc tccagccttg cgatggtttc tttcagcctg acatacatgg aatgcatatc
     5521 atgagccagt gcgccaagct catcctttcg ctccagcggc ggcggtacat ctttcaggtt
     5581 tgccatttta ttcgcactgt ccgctaaggc tttgatcggc gttgtcattt gccgcgcaaa
     5641 gatatacgcg cataaaaggc tgaatacaac cattatcgca atcataacaa ttccccgaat
     5701 tgtcagccct tgataaagca atcccacacc tgccttgctt tgagcaacaa tcgaaatatt
     5761 atcatctcta tgtaccacat aaagaaagtc gggtctaaaa ctatttgatg tattggcatt
     5821 tggtgtggca tagagtacgc ttccctcttt atcttcaata taaaactcaa aggattggtt
     5881 attgtagtga aacagccctg ccacctcttg aatatcaagc ctatcgctat tctgaatcag
     5941 ttccaccaat ggctgatagg attttactgt ttgctgtaat tccatcactc tgaaataaga
     6001 cacaaattgc tgtgcaaaca gtgttgctgt tacaccgaca agcagtagca gggcaatgat
     6061 cgtataggaa aaaaccttaa tgaaaatccc ttttctttcc attattatga ttcctccaat
     6121 cggtatccta caccgcgaat ggttttgatg atattttccg gcagcttggc ccgcaaattt
     6181 ttgatatgag tgtggactgt gctgccatca ccctcaaagt catatcccca tatacgtgac
     6241 aaaatgattt catgcgttaa ggttctgcct ttgttctgca ccagcagcaa aaggatttca
     6301 aattcttttc gtgtcagggg cagctctgta ccgtcacaaa gtaccgtgaa atcctccggc
     6361 agaagtgtca gcctgccgac acggatttcc tttgccagcg caccgctgcg ccgcagcagg
     6421 gcttccaccc gctttagtaa aatctgcatc ttgaatggct ttgttacata gtcgtctgcc
     6481 tctgcatcaa acgcccggat ttggttttcg tcatccgaca gggctgtcat catcagaatg
     6541 ggagtatcat ttttcgcacg aaattcacgc aaaagttcat gcccgttcat accgggcagc
     6601 ataatatcaa gaataaccag ttgataagtg ttttcgtaaa acttggtgta tgcctcattt
     6661 ccatctgtgc aggcatccac ctgatatcct gcctcagcca gaaacgccct tactgtatta
     6721 cagatatgat catcatcctc gacaagtaga attcgtatcg acataaaaat ccctccattt
     6781 taagaagata acataacagt ctgtagtttc cctgtagttt caaagcgatt tcttttcgga
     6841 ttttaatcat ccgtcattgg gatactcgct tcttttcatg gtgtatgtat ctatattatt
     6901 ggtttaaacg aattaaatca agataataat aattaacacc ttcttaatgt ttgggatgtt
     6961 tcgattacag cggttgtcaa aacatcccga taatactggc aagcaatgga tcagaatatc
     7021 ctttacggat attctgatcc accacttgcc cgcctgcggc gttctcgttt tgcttgttgg
     7081 ggacacccca agcctcagca aaatgcgcgg cctctttttt gcgaatgcac cttgcggtat
     7141 ggcttttcac acaggcaggg cctgtgtgta ctccctccgg tcgctcttgc cgcactccgc
     7201 gcagcagatt cagtcctaat accgttcaag acagtagaaa atcagcaagt ctatattcct
     7261 catatcttca tcatccgtgt ccttgcagtt acaggaaatg taataatcgc caaatgtaaa
     7321 tcccagaata ttttcctcaa aaagccgtac ctccccggta ttaaaatcaa tcaccccata
     7381 ctcaaaggcg cattagacca gcagttatcc aatgtctgga gacttcacca taaagaatcc
     7441 agatgccggc cttttcaatt ctaccatata cggctgatac agcagcagct tcctcgtctt
     7501 tgtttcgggc attttccatt tctgtcatga taaagtttcg cttcttcata catccatgtg
     7561 taaatctttt ctttctgttt cagatgagaa tactttttat cggtctggag cagcctgcca
     7621 tctatcatct tatagttttt ccgtgacaaa ataccatgct ttctctctct tcaaaaccat
     7681 atccaaaatg cgccggtttc attatactat tcagtaaccg cctttccttt ctttgtacgc
     7741 ctgtcaatcg gcttttccgc agttttggga atgagccaga tcgtcgccat ctttacagcg
     7801 ccggggatgc gtcccgcagc acaatagtag tttatccatc gtgggggcac accccatttc
     7861 tcgcctgcct ctttcaacgt catgtagtcc atagtacacc tccacagggt acattataat
     7921 tcttttgctc gaagaataaa agaaacaaaa tgtgaaatat aaactttaag aaaggtgcat
     7981 ataccaacat tccacgggca gagtatgaaa tatacaatgt aagtgggagg tgcgatatgg
     8041 cgaatattga agattgtccc ggctttgaaa ctttcggcgc ggatgtgaaa gcggcccggc
     8101 aagcaaagcg cgtttcgcgc aaagcaatgg cagagaaaat aaatattgac tggcgctatc
     8161 ttgccaacat cgaaaacgac ggggccattc ccagtctgcc ggttgtcata cagcttatta
     8221 aagcctgcgg gcttcctgtg gaacgctact ttaacccgga gatcatgcgg gaggaaagcg
     8281 aactgcggca aagggtcagc cacaagctga aactctgccc cgaagaatac ctgccgatca
     8341 tcgagggcgc gattgacagc gccatactaa ttgaaaagcc gaagaagaat gaaacggagg
     8401 atgtgtaact ggcatcctct gttttacttt tagcgggagc tgcacagcgt agcttctatt
     8461 tttttgcact tttttctttc cagagggcta ttttgcgggt agtttggggc tttggaaacg
     8521 tcttgttagt ggagaaacag taacgtagca agcataggga gtgtagccac tcccggaaaa
     8581 acggcctgcc ccgtccctgc cgggccgcgt ccgttttgct tgttggggaa atccccaaac
     8641 ccctgaatgg aaaggacggt gaagcatggc aaacagaaag cgaaaaatcg tgctgcgcgt
     8701 ccctgtgacg ccggaggaac gggctatgat tgaacagaaa atggcgctgc tgcatacgaa
     8761 gaacttttca gcctacgccc ggaagatgct cattgacggc tatatcgtca acatggacac
     8821 cagcgacatc cgggcgcaga ccgccgagat acagaagatc ggcgtcaacg tcaatcagat
     8881 tgcaaagagg ctgaacggta tggggccggt gtacgcacag gacatcgagg atataaaggg
     8941 ggcgctggcg cagatatggc agttacaaag atacatccta tcaagtcaac gctgaaaaaa
     9001 gcccttgact acatcgagaa cccggacaaa actgacggca agctgctggt ggcctccttt
     9061 gcctgctctt atgaaacagc ggacattgaa tttgaaatgc tgctggcgca ggcataccaa
     9121 aagggcaata atctgggcca ccacctgata caatcctttg cccccggcga agccacgccg
     9181 gaacaggccc atgagatcgg gaagcagctt gccgaggaag tgctgcaagg gaaatatccc
     9241 tatgtgctga ctacccatat tgataagggc cacgtccaca atcacattat tttctgtgcc
     9301 gtggatatgg taaatcagcg caagtacatt tccaacaaac agagctatgc ctatatccgg
     9361 cgcaccagcg acaggctgtg caaggaaaac ggattgtccg tggtgaagcc cggccagagt
     9421 aagggcaaga gctatgccga gtgggacgcc cagcggaaag ggacgagctg gaaagcgaag
     9481 ctcaaagcag ccattgacgc cgctatcccg caggcaaaag attttgatga tttcctgcgg
     9541 ctcatgcagg cgcaaggcta tgagatcaag ccgggaaagt ttatttcttt ccgcgctccc
     9601 ggacaggaac gctttacccg ctgcaagaca ttgggggaag cctacaccga ggaagccatc
     9661 aaagagcgta tcaaaggccg cgttatcacc agagcgccca aagagcgcaa ggggatttct
     9721 ttgcggattg atctggaaaa caacattaag gcccagcagt cggcaggcta tgagaggtgg
     9781 gcgaagctcc acaatttgaa gcaggccgca aagactttga atttcctgac tgaacatggg
     9841 atagacacct acccggattt ggaaagcaaa gtggccgaga tcaccgccgc cagcgacgag
     9901 gccgccgcta ccctcaaagc tatggaacac cggcttgcgg atatggcggt gctgataaag
     9961 aatatttcta cctacaagca gctctggccc gtggctatgg aataccgcaa tgcagcggat
    10021 aaggcaaaat tccggcgtga gcatgaaagc acgttgattt tgtatgaagc tgcggcaaag
    10081 gccctaaagg gacagggtgt gaaaaagctc cccgatctgt acgccctgaa agccgagtac
    10141 aagcgattgg ccgaggaaaa ggaacggctg tatgagaagt acggcgaagc gaaaaagcag
    10201 atgcaggaat acggcatcat caagcagaat gtggacggca ttttgcgtat gacgccggga
    10261 aaggaatgga cgcaagagct atgagtattc cacgaatgaa ttaccctcaa tatcgcaagg
    10321 cccggaagct gacgcatgag tgctgcaact attgtgacgg caactgcctg ttgctggacg
    10381 acggcgaaga atgtatttgc gtacagagca tttcctattc gcttctgtgc cgctggttta
    10441 aggccgctgt cctcccgctg gatgcggccc tgtatgccga gatcaccaaa gaccgggacg
    10501 aagtgaaacg ctgctgtgag tgcggggcca cgttcacgcc gaagtctaac cgggccaaat
    10561 actgcgcggc ctgctccaaa cggatgcgcc gccgcaaaga ggccgagcgc cagcggaaaa
    10621 gatactggaa acctacgcac ttagagctgt aaaagccctt atatttcaag gcttttccgg
    10681 catggtcagc ggggtatgtg ggtgttttat cctatccccg ccgaagtgct gttctaaatg
    10741 cgtagaattt accagcagaa aagcgccgtt ttctctggtt ccatgcttcc gaatatggta
    10801 tcatagaaaa aatcagtctg acgggggtat caggatggac ggacaagaaa agctgctgga
    10861 ctatgaaacg atcaaagccg ccgttgccgg tgagaggtgg gccacggaaa aagtgttggc
    10921 ccattatgct gactacatca acgagctttc cacggtggag atcagacagg caaacggcaa
    10981 aaagaagaaa gtcattgacg aagatatacg gcagcgcatt tccctgaaac tgctggaagc
    11041 attgccgagc ttcccgctgg aacagagata gacggcaaga gggctgcacc ctcttacgcc
    11101 gctttgcggc tatcacctgc acacccctga aacagataca cccgctgcgc ggctatatct
    11161 gtttcagggg tctaattata gctgcaacct acgcatttaa gggattgaaa accgcccgct
    11221 gcaaggcttc tcccgcatgt ttgcaggggc aagcgaatac ttcatcctat ccccgacaat
    11281 accgggttct aaatgcgtag gaataggcaa aaagaaaaga cgccggacgc aagcgaccac
    11341 atggccgccg cgcccggcgt ctgctgttcg ttattcgtct gtgaagtgga acttctggcc
    11401 gtcatagtcg gcatccgtca tgcgttccag cttggaaagg gtctgctggg cctgcgcccg
    11461 catatcccca tccataacca gcatgacggc ggtgagcctg tttatcgttc tgcgccggtc
    11521 tgcattgtgg tacatacaga tcaggttttc ttcctccacg gtaaagtgca tcattcctta
    11581 tacctccaat tcattctttt tggttctggc cgccgccttt tttgggctgg cggcctgttt
    11641 gctgtcggat agctgcttgc ggatagaggg ccggggcctg cgaatactca catcccggcg
    11701 ctcgtcccgg ttaatcacgg catacacgcc atgcctgcct ttcatcccgg taaaacacag
    11761 ggatttatag ggcagcatgg caaagagccg gtcattatcc ttggtggaag caatcgccgc
    11821 aaagtgcggg gagatctcca ccatgaaatg cgttttattg gggctgttag gcgcggacag
    11881 atctttcagg ctgtccacaa tacgccgggc ctcggtttca atccggctgt catgcaaagc
    11941 ggtgacgtgg actttgaaat cgccggggac ggcccgcccc cggctgtgct gctccgtccg
    12001 tagcgcctcc tgcagcacag ccgggtcatg gggctgggcc tcatagtaca aaaagtttcc
    12061 caatacccgg tcagggcttc cgtcaaaacg ctggctctcc gggatgtcac gggtgccatg
    12121 ctcataaaag agccggttca cactcaccgg ctgggcggtt tcaatgacgt gccggaaatg
    12181 ctgcggatag tccagctcat agagattgcc ccggatagtg ccgccctgtg tgccggtcag
    12241 ctccaccgcg taggccagta tcttgtcacg ggtctgctcc ccgtaaaatt tccatgtgtt
    12301 gtactgtcgg gtgtctttca ggaaaacatc acgttcccgg aaacagtacg tcccggaggg
    12361 ccgggacatc cagagcaggg tcttgtctgc ggcctgatcg ctggcggcat cccgcctgat
    12421 aatgtctttg tcaatgccaa agtcactttg ataaaacgcg gtgttctgcc gcatgatctg
    12481 ttccagcgcg gccagaacgt ccacattttc aaacttctgc atttactcta cctccaatcc
    12541 ctttgatttt tcccgcgccg gtggctgctt ggcctgttcg gtcttggccg cgttgagctg
    12601 cgcccggata gagggctttt ctttctccct gcgggccgca agctgtaagg cgctgggctt
    12661 ttcgccggaa aggggctgga tgcacttgat acggtcagcg acgcggattg tggtgtcgtt
    12721 taactgccgc tgccatgccc cggccttggg cgaccagcgg aaaccgttgc ttttcagctc
    12781 gtcgcgtaca gcagcatccg gcttcccctc aaagaagatt tgcaggcggt tggccacccg
    12841 gttgatctcc acagtgccgc cgtcaaactc ccatcccaca taggccgcct ccttttggcg
    12901 ggtcaattcc tcaatgcggc cctttaaccg gcgtatctcg gcgttattgt tggagagctg
    12961 ccaggactgg aacggttttt tctcatagtg ccagcccgac gccatatccg ctttcaggtt
    13021 ttcaatgcct ctttcggtca gatgggggca tccgtccagc gtcccatgct tgcggtagta
    13081 ggcattgacg gccttcatca actcctgcga cgcttccagc ttttccagtt tcttttccag
    13141 cttggaaacg gcctgcggat cgtcggcgct gataccaccc atgccggtgc tgcggatttt
    13201 gtcaagcaag ccctgaatgt actgaaattc ctccatgttg cggtcactgg cggcgttctg
    13261 cttttctttc gcccgtaccg ggaaattgga cggcccggca atcaggacag aggggacgcg
    13321 ggcggtaatc tcatagccct tattcatgtt ctcggccagc ttgcgggcgt aggtgtcaag
    13381 gaggctgtct atcttttcgt gatactctgg ctccacacgc tttttctggc gctccgcaat
    13441 ttccacggcc tgatcgacat agtgccggta ttccgccgtg gcgctgccgg gccggtagtc
    13501 agaaaagctc atggcttcct tggcgcggcg ggcggctccc tcattgatgg gataatagcg
    13561 gacagccgtt tgcgggggcg cagcctccgg gggttcctcc tgtgtctggc cggaagcaac
    13621 tgccacatcc tcaaaagata gctgttcggg ttcctccggc tgcggttcgg gcggcgtatt
    13681 gttgataatg ccgtcaatca tgttttcgtt ctgctccgta gacagttcgg cggtacgcag
    13741 gggattttcc cgcaaaaact ccggcacttc catatagccg aagctgtcta catagtgggc
    13801 ggtgtcctgt ccattctggt gcagcaccac cacgtcggaa acggaaaggc tgtgtcccct
    13861 aaaatctgcc gggtggtcga tgttgaatgt gcggtaaata tcctccaaag acgtgctttt
    13921 atccagcggt gccgtataaa caaggtcata gttggcactg tccacggcca gccctgcggc
    13981 ctgtaaacgc tcgtatggct caaaccgata gtcgcgggtt tcctccccgc ctcgaagctg
    14041 gtagatggaa aaggtgtcct gttggggtgc ttcatagcca gccgccgcgt attcctccac
    14101 ggtcataccg gctgcggcgg cctcctgcgc gatctcggcc tgtacctgtg ctttgtagtc
    14161 ctgcaagctc tggtcgaagt cagccagttt cggcggctcc ggcaactgat actggccctg
    14221 attgagcatg gggcggcact cctgcacata agagagaagc gcccccaaat aggccgtttc
    14281 ctccggcgtc agggtttccc cggactgtaa gcggccctgc gccgtctgtt ccatttgggc
    14341 aaggctgcaa tgcagcttca tataggggac aaactcgcct aacagcatat cccgatgggc
    14401 cttgtcctgc tcccagccct ctatgccggt tgtagcgatt acatgctttt tccagttttc
    14461 gtcctgcgcg taaaattggt ggtagctctg gatatgttcg atcagggaac cgtccctatc
    14521 tccaaaatcc tgccgcccct cgtagctgtc cggctcgccc tgaaagatac agtcaatgcg
    14581 gaacgcggtt ttgtcatagc ctgcctctgc cggatatgct gcatccagac gggcaaacag
    14641 cgcgtcggcc tcatgcaacg gcatttgctg gccgtccttt agctgggggc tttcgctcca
    14701 tagcacagtc acaagcggct cggctgccgg atcaagggcc ggggcctgtt cttcctcggc
    14761 ctgcgccggg gccgctgcct ccggggtaac gtcaaccgtg acggcctcct gttcctgccg
    14821 ggcctcgcgc tcctgctgaa gctgggcaaa atggccgtcg atctcggtta tcaattcgct
    14881 ggccgtggcc cggatggttt caagggaggc tttcagctcg gataactccc tgccgctgct
    14941 ccaatcggcc acatagccaa aagaatagtc cgacgtgtcc agcccgtaat actggcagac
    15001 ggtataggcc acgctttcgg cctgtacctc gcgggtgctg cggtctggcc gggccgcctg
    15061 ttcctcggcg ggggcctccc ggtcaatggc gtggagcttg gcatgggcaa tctcatggat
    15121 ggcggtcttt agggtctgca attcgctcat gccctcgttg atggcaatgc gctgttttgc
    15181 gtagaagcag cggcccttgg ccccgtctga aatcggctca atgcttatgg gatagggtga
    15241 tgtccgttcc agcgcggcaa agaaatcctg atactgctgc acgtcgccgg taagttcact
    15301 gatatagggc atgggaaaat ccttgccctc ggtctggctg atgtcaaaga ctgtcaccac
    15361 cttaaaggcc ggaaccgtca cttcctgttc ttcggtcacg ggcttgccgt ccgcgccgat
    15421 cacgggctgc tgggtggccg ggtcgatttt ctccatctgc tgcttaacct tgaacggggc
    15481 cggggccagt atcttaatgc ctttctcgcc ccgcttcaca tggcggtcaa attcatcctg
    15541 ccacctgtta tagcccgcca caatcgaacc gccctgcatg gcgatcagca gcgtattgtt
    15601 cagactgtaa tcgtgcatct tggacatagc ggataagtaa gccatatagc ggctactttc
    15661 aaaaagctcc tgtacgccgg tttccagacg gtcagtaatc actttcatgc gttctttgct
    15721 gttcatgccg tccagcatga tcgggataac cgggggcggc gctttgtcgg ggctttcgga
    15781 tgcctccggc tgctgggcct gcggttcctc ccggtcagct tccggctggg ggtagtgcat
    15841 cacccggtat tcctccggca ccggctggcc ctcatggacg cgctgccatt cgtcgccgct
    15901 tctcaccaga tagccgtact gggtaaaaac gccttgttcc tgctgggcaa tgtggcgtcc
    15961 aaactgcgcc gtatcaatcc cggctttcca ttcctccggc atatccacca tgccggaacg
    16021 gttcaggtag tagtcgccca actgtccatc ccccctaacg tcgggaagat gcacatagta
    16081 atccacattt tcggtgtagt cgatgatctg gccgatattc tcaaagccgc cacggggatt
    16141 ttgcagggcg gcgttcagct ctgcgatctc ggcggcgtca agctggccca gccgggcggc
    16201 aaggaaattc agctcgtcca cgtcggcggc cagcaccatg tcatagggaa tggcaaggtg
    16261 tctgtcctcc gggcaggaat acccgttgat aaaaaaatcc tgcggattgt cggcagtaat
    16321 gccaacatcc cgcagggcgg cttgcagcgt ttcggttgtg gtgggcaaat ccagccagac
    16381 gccttgtttg ccctgttcca aaaactgccg gttatggact tggatagaaa atacttcgtt
    16441 cacgcggtca ctcctttctc tgttctgttt caaaaaatag ggggttgggg acttccccaa
    16501 caagcaaaaa tccccggccc ggcagggacg cggccggggg attttaccgg gagtgtagcc
    16561 acactcccta tgcttgctgt gttactgtcc tttagctcct gtgttcaatg cggtagttga
    16621 cgtacttgcc cccggtatca gccaaaagca ccgtcccgtc gtaggttttg ccggtcttta
    16681 cggaatagag gccctttacc ttgactttgc cggttttgag cagcgcagcg gcgatcttcg
    16741 gggtgaacgc tttcttgcgt tcctcaaaaa atcggtcatt cttccacatg acgaactggc
    16801 aggcccggtt tccgcagtag tagtttttct tgccctcata gacagcctca ccacagcggg
    16861 gacacgtccc gataggaaca cgctcggcct gaaacaattt ctgcttttcc tcactgatac
    16921 aggaataggt ctgcaccagc tcccgcgcct gcgtctcgat gccgtccata aattcgtcag
    16981 gatcggcctg ccccttggcg atctcggtca gccggttttc ccattcggca gtaagctggg
    17041 gagaagtaag cgcctccggc agcaccacag ccagattgat gccgtccttg gtgggaatga
    17101 gctgcttgcc ttttctctgg acaaagccca tctgcaccag cttttccaga atggcggcgc
    17161 gggtggccgg tgtgcctaat cccttgcgct cggcatcctc cggcatatcc tcggccccgg
    17221 cccgttccat agcggacaaa agcgtatctt cggtgtaggg cttgggcggc gtggtgaaat
    17281 gctcggtgac agaggcggcc acgtctgcaa aggtctggcc ctcgcaaagc tccggcagct
    17341 cccgcaccgc ctcggcgtcc tcgtcggcgt cggtctttaa ggaagaacgg aaccggcgtt
    17401 caatctcttt ccagccgggg gaaaggacgg tcttgccctt ggcggtaaac tcctgcccgg
    17461 cacaggtaaa tgtggcggtg acggcctcat agatatgcgg cccggccacg gcacataaga
    17521 gcttgcagca gatcagggac agcagctttt tttcactctc ggccagagtg ccaaagccct
    17581 gcttcacaaa ttcagcggtg gggataatgg cgtggtggtc ggacaccttt ttgctgttca
    17641 ggatgcggtc aaactgcggg gaaaggttca ggcccttggc aaacggcacc agctcccaca
    17701 ggccggacac aaggctttcc acggcgggca gcatatcgtc ggtaagatat tgactatccg
    17761 ttctcggata ggtcagcagc ttctttagat acagtgcctg ggcatagtca agggtctgct
    17821 tggcggtata gccgaaaagc cggttagcct cccgctgcaa ggtggtaagg tcatagagct
    17881 tgggcggctg ttccgtcttt ttctcccgcg tcacggaaac gcaaacggcc tgcgcttttg
    17941 cacaagccgc cttgacggtg tttgcctcgg cagcgtcgga aaagcggctg cttaccgcgt
    18001 ccgcgccgcc cgccgtgata tggacgatgt gatatttctc tttcttgaaa tcggtaatct
    18061 tggcgtccct gtccaccagc atttttaagg tcggcgtctg gacgcggccc acagtcaggt
    18121 tcttgtggta caggacggaa aaaagccggg tggcgttaat gccgatcagc cagtcggcct
    18181 tggcccggca cagggccgat tgatacagcg gatcatagtc gccgcccggt ttcaggtggg
    18241 caaagccgtc cttaatagca ctgtcctcca tagaggaaat ccaaaggcgc tcaaagggct
    18301 tttggcatcc cgccatctgg tagacgaaac ggaaaatcaa ttccccctcg cgcccggcgt
    18361 cggtggcgca cacaaggccg gtcacgtcgg ggcgctgcat cagcgaacag agaacgtcaa
    18421 actgctgttt cttgtcgtcg gggacgatgt actgccatgt ttccgggaga atgggcaaat
    18481 cctcatagcg ccattttttg aaacgctcgt catagcgtcc ggcgtcggca aaggacacca
    18541 gatgtccgat gcaccagctc accagatagc cgttcccctc caaatagccg tcgtgtttct
    18601 ccgtggcccc gatcacgccc gcaatgctgc gggccacgct gggtttttcc gcgattacaa
    18661 gtttatatgt cattcctcgt cctcctgttc actcacaaaa tcagcttccg ggtcaaactc
    18721 ggtttcgggt tcctcgtcct ccaaatcctc gtcctcccca aaatcatact cgcccaaatc
    18781 gtcgctgccg gtggtttcag ccttgggctt tttgaacttg aaatagtaaa gggccgcacc
    18841 gccgcccgcc agcgccacca gcaggaacac gatcaggccg cccgcgccgc ccttgggttc
    18901 ttcctccggg gcttcgggtt cctccggctg gggttcctgc ggctccgggc cgctgcactc
    18961 ggtcaggttg gttttacata ccgggcaatt cgtgttcaca gccccggcct tgcatttcgt
    19021 ggtacaggag cagacagcag cgggggtgac ggtttccccg tcctccatca gcgtcagcag
    19081 atcggcttca tccacctgat ttaagaaatg gacagtttct tttccctcgt cgtcccggtc
    19141 aataatcaga taaaacacat tgccgttttt ggtttccacg gtgataaact gcttgccatt
    19201 tttcgcggcg ctgccgatgt cgtcaatcag tgacaggttc ccgtccgggg acagggcggc
    19261 gctggccccg ccgccattga acagttccag cagagaagca atttcctccg ggtcaatgga
    19321 gagggaaaaa ccgccctcgc cggtagccgc tacttccttt tcgctgacgg tcatatagtc
    19381 ggaatggaca tagccgatgc gctccggcaa gagaatttta atccagtcgc cgtctgtgcc
    19441 gactacctca accgtcgtcc cattgggaag ctgggtgaac gcggtcttgt caagccccgc
    19501 gccggtgcgg acattcagcc tgccgccgtt ggtggtgacg gtgccggtct gttcaggttc
    19561 ttttttgtcg gtgccggtgg tgatctggat gccgtcgtcc gtggcggcaa tgctcacctt
    19621 ggaaccgaac agcgcggaaa acaggtcggt gatgtccttg ccggtcagag ggccggtatc
    19681 tttttcggcc tcggtttctg tcccgtccgt ggcggtgccg gtttcgtctg tttcaggctc
    19741 caaaccgccc gtagcgggtt cggttgtagc ctccggcagc ggggccggtg ccgggtcatt
    19801 gccgcctgca agggcggtaa cgggaaaggc cgtgacgcag agcatcacgg ccagaagtgc
    19861 ggggagaata cgggaaatcc gtctggtctt attcttcatg ggcattgtcc tcctgttcat
    19921 ggtaaggggt tgcggcaggg gcggcctgca ttgcgccgct gcgtaagaac gcggcaaatt
    19981 cctccggctt catgttcatg ccgcgcacaa gctggatgat ctgcaaattc tcctgttcgg
    20041 ttttctgcgt ttccagctcc cgaagctgtt tctgaaactc cgcgatctta gacttggttt
    20101 tctggatgtc cttttcgatg cggtcaagtt tggttgccat aattgaaagc tcctttctgg
    20161 cgttaaggta aacgcccgta actgtaaaaa tgggattgcc agtagtttga agtaaggttc
    20221 gtgtaggaaa tcgggttccc gcaatgcagc atcacattgt tgcccacata caggccgacg
    20281 tgggacacgc cgggggtgtc gtaggttccc ttgaaaaata caaggtcgcc gggcttggcc
    20341 tgcgaactgg aaacaggggt gcagatgtta tataggccct gcgcccccag ccgtcccacg
    20401 ttccatccac tatgattgat tacccacgaa atgaagccgc tgcaatcaaa gctggtgctg
    20461 ggagagctgc cgccccacac atagggataa ccgatatatt tttccgcctc tttgagcatg
    20521 gcggcaaagg tggcatcctc caaagcctcc gggggtacgt cgtagtaggt cggcggcgtc
    20581 agggtggagg cgttggggta ctggctgccg gaaaacagat caggccggtt tcctagcgtg
    20641 gacatataca gggaatagaa acttagcgtt tcctcgtcca tgatatagac tggcacatgg
    20701 gacaggtcga agttttccag cgtgacgtag cagatgtaat agtcatacgg cacttggtag
    20761 gtgtctgtat gggtgttgcc ctccgcgtcc gtccatgtat cggtttcggt gcggtaacgg
    20821 gtttctacca cgacgttttc tgtcaggata tattgcttgt caaagagcat ggacaaatca
    20881 ccctgtacct ccccgatggt aaatatcccg tcatggagcg ccgacagaat ggaaatcagc
    20941 acataggggt catggctgat ctcgtcaagg tcaaaatggt attcgtcata gtcatgggtg
    21001 gcctcgtagt tgtccagata gtcttgcagc tcggcttcca gctccgcgta ggcgtcctcg
    21061 gcggccaaca tatcgctatc ctcggaaaag taagaggacg ccgtgatgcc gcttccggcg
    21121 ctgccgaaca tggcggtgca ggactgtaag ccgccgatga taagcagcat caaaagcccc
    21181 aacacaagga cggccagcgc ccctttccag tggcgggcca caaaggaggc cgcccgttca
    21241 ctttctttgg ctgcggcctt ggccgctttc gtggaggccc cggctgtctt ggccgcgccc
    21301 tgtgccgccg cgcctgcggt ctggcccgct gtccgggcgg ccttggcgta ctggcgcttg
    21361 atctgctgtt tctgccagaa ccgggaaatg gggttgctgg ccgcctgtgc gatctccggg
    21421 ttatcccgca aagatttctg gtagaaatac tccgcgttgg cagacaatag cctgcgctcg
    21481 gccttttccg cgtcccagta gggtttcagc ctgtggtgcc ggatggtgct gcggatggct
    21541 tttccggcct gccgctcggc aagttcctcc cccttatggc cgccctccac acccacgttt
    21601 tcatgctcga cttcatggat tttcccgtgg ccgaatagaa aaacctcgga aacaggacgg
    21661 cctgccggat tgggtttcag ggagggaggc cccttgtcct gtttgtcaaa gtgcaggacg
    21721 gtctttgctt tgccgcttgc ctcgtcaaag acggtttcct tgaccgggac gcgcttcttg
    21781 gggatggcgg cgcgggcctt atccagctta tcggcccgtt tgtccgattt tcggatatag
    21841 ggctgtaaat ccgggtcggc ccgttcttcc tccgacagtt ggagccgggc ggatggccgg
    21901 tgcagggcag cgtccccctc ggcggccaca gccccggcct gcttcgcggc tttcttggcc
    21961 ttatggccgt catggatggc gtcggcccgt tccagcagct tatcggcggt gccgcccggc
    22021 cccggcgcgg acaaatcctg ttcggcctcc cggctggaaa tgttctccac ctcgccggtg
    22081 gcctgatttt ccagcgtcag cccgtcgcgg gtcatggcct gcgtcacttt cgccttggct
    22141 ttcagctctt tcatggtggt tcacctcctt tgtggcgtcg ccgggtcata ctcccgccac
    22201 ctcgtttaag cgggtcgtca taatcttgta aagctgggtg ttgtgcggga tggggttggt
    22261 aaagggcagc accacgtttt caaagatcaa aaggccctcg ccgggttcgg aattgtcgat
    22321 gtacttctgc tgttcggtgg acaaattcaa gcgttccgca aggatttttc tatccccgga
    22381 cgcctgattg agcagcgtaa tgaagtcgct gttttcaagg atattttcaa tttccgggga
    22441 ggaaagcagg tctttgacgt tctgggtggc acctgttgga atgccgcccc atttcctaaa
    22501 ccgcttccaa atctccgcag aataggccgc cgtctgttcc tctttcaaaa gcaaatggaa
    22561 ctcgtcggca aaataccatg tggcctttcc ttggcttcgg ttggccgtga cgcgccccca
    22621 tatctggtct tggacaatga gcatccccag ctttttgagc tgcttgccca gctccttaat
    22681 gtcaaaggac acaagccggt tgccgatgtc cacgttggta cggtggttaa atacgttcag
    22741 ggagccggac acatacaggt caagggcctg cgccacccgg tcagcctccg ggacatgctg
    22801 atctaacaac gctttgtgga ggtcggacag gatcggcata ttctccgggc gggggtctgc
    22861 cagatagggc cggtagatca cgcgcacagc ccggtctatc acggtctttt caatggcttc
    22921 cagcccgttc ttgccgccca tgacaagctc acagaacgac agcacaaagt cggatttcag
    22981 ggccagcggg ttatcgtcct ccgaataatt caggttgatg tccagcgggt tcacaaagtc
    23041 cttgctggta ggcgacagcc ggattacctg tccgtggagc cgtttgacaa gggggtaata
    23101 ttcggcctcc gggtctgaaa taaaaatatc gtcaggcgtc gttaagaaca cactgacgat
    23161 ctcggattta cagctcatgg atttgccgct gccgggggtg ccgagcttca aggcattggg
    23221 gcaacgggcc tgcttcctgt ccagcataat catgttgcgg gacttggcgt tgatgccgta
    23281 atacatggcc gcgccgccct gaaaaagctc ctgcgtcaca aaggggacga acacggccac
    23341 gctggaagtc gtaaggctgc gctgtatctt gatctgattg acgcccagcg gcaggctgct
    23401 tgcaaggccc tgttcctgct ggtagtccag ccggacaagg ggacagttat gcttttgggc
    23461 cacgcctgcg gcttggaaca cgtcgttatt cagcttttgc ttggtgtcgg ccacgttgag
    23521 gacaaggaac gtcaactgga acagccgttc attgcgggtc tgcaactttg tcagcagctt
    23581 cttggcgtcc tcgccgtagg tggcaaggtc gctgggaaga atgtccatat cgtaaccgct
    23641 gcggacggcc tttttctgct ccgcaatctt catagcgtca aggtcggtaa ttttgcgctt
    23701 gatggtcttg atcgccttgg tctgttcaat ggcctgcaca tggagattga ctaaaacacc
    23761 gctttccgta ttgaggaagt cggccagcat atcgtccgac agctccgggg acaggatttg
    23821 caggaaactt accgcgccgt atttgccgcc catgccgaat gtctttgcat tgccgaagca
    23881 cagggaggac ggggcaataa aatccttggt ggagaggccg gacggggcca gccacttcca
    23941 gtcaaaattg aatatctcgc cgtccgggtg gtacacgcca tgcagcaggt tcagccgttc
    24001 ccagccgtcc atcacatggg ctacggcccc catgctcttg aaatagccta acaggtcaaa
    24061 gccgatgcgc ttcaatctgg ctcgcgccgc tttcacgctt tcggcctcga tggtgaatgt
    24121 caggtatttg gtctttacca tgccgttgtt gccgtttgca agctgctttt gcagaatgcc
    24181 ggtgtactcg gcccggatgt cgtcgaagtc gtccccctgc ggcgcgatct caaagctctt
    24241 ggcgtactgc accgggtcaa ctttccgatt gaggaaagaa aactggatat gaatggaggc
    24301 gtccacatag ttatacaggt cgcacagttt ttcaaagata gccgtctgcg tgtccggctg
    24361 ggcaagctga tagctgatgt ccgcaaactc aatgcacttg gaaaagacgc cgggcgatac
    24421 ccggcacacg ccgtccgggt acatgacctc gtaggggatg ctctgctgcg ccgtgtgggg
    24481 cctgccgtcg cccttatatt tacggattac cgcgtcaatt tcttttcgct gggcgcgggt
    24541 cagctttgtt ttttcggttt ctcttgggat ttcctttttg gacaatggcc tttacctcct
    24601 gttccatctg gtattgccgc acaagggcgg tgtaggtgtt gtcggtctga tagggacgct
    24661 cctttggctg gatgaagcag cactggatga tctgcataat caccacttca aggggctggc
    24721 cgtgacgctc gtacatggca agcaaaaagc ccggcagcat ggcaaatacc atgagcaggg
    24781 ccgccgcgct gttggtaaga tagtcacggg tgagaaaata taaggggacg ccgatcacca
    24841 gcgccccgga aaaacagatc agttgccgtt tggtaagccc aaacacaacc ttgcttttca
    24901 catgggttaa gtccttgggg acggttacat aagccatttg gcacctcctt tcacgtcagg
    24961 ataaggtcac attccacctc gttcccccac acgtcccagc cgggggtttt ctgtctggca
    25021 aacagctcca cgcggggcaa atcgcccgcc agctctacga ttttttcacg ggtcacatcc
    25081 ggctttttgc tgtgttgttc aatcgggctg ataataaact gatggacaga ggcagaacga
    25141 cgcttcggct tgccgtgtgt tgccagcagg cagatttccg cgtttcccct tgtccagcgg
    25201 cccagcccgt aaaaccatgt aaggctttta cggttctgtt tcagccatac aaaagccacg
    25261 gtcttgaatg aaaagcccca cgctttgatt aaccgcagag cttccggcag catggggaat
    25321 gtggcccaca aaaacagcag gcagtctttg gacgccagcc gttccaccgg cagggcgcac
    25381 agctcgtcaa tgctcatggt ggaatagtga ttttccgctg cgccctgtac gtttttgcag
    25441 tcataccgcc acggcgggtc agcgtaaatg atgttgtacg ttgaaataag caagttcctc
    25501 ctgtgtatgc ttggattttg ggatcaatgc gccccgaata cggcctttga tatactgccg
    25561 gtcttgaaca ggcagaagca cagcagcacc gtatagccca tacagcccca gattgcgccg
    25621 gatatgtcgg aagcggaacc gatattctgt atcagcaccg cgtagatacc caccacaacc
    25681 atgattaaaa aggcttggaa gcccagcgcc agcagggatt tcagataccc ttggcccatg
    25741 ccgcgccatt ccgcgttgcc cattgtggca agggggatag gccccagcga cgtgacaaca
    25801 tagatttcca ccatgcggcc ataggtcaca aggaaaatgc agatggaaag gatattcatg
    25861 gtgaggccca caacaagggt ttggaaccac agccccaaaa gagcgcccac gctcatagcc
    25921 tccaattggc tttcaaggtc tggtatcagg gtgttaaaat caatggatgt ctgcccgata
    25981 atcacaccgg cgctttgatt gacgacgctt tgggtggcgt cgaatacgcc catgacgatg
    26041 ttccatgtgt tcgttacgat caggattgca aacgcggatt tgaatatcca gcggaagaac
    26101 atggagctgt caaagtcgtg catattgttc ttttccgtta tcatctggat aagctcatag
    26161 cacatgacaa gggcgagtat ggccccggct atggggacga tcacggtttc cgacaggctg
    26221 tgcagcatat tgaaaatacc gctgttccat gcctgcgggg ttcgtcccac gtcggcggcg
    26281 atttctccga ctttggcatt taccgtatcg aacagcccgg acaggttgcc cgtgataccg
    26341 tccatgagga tgccttttat ccattcttca atgatttcac taatcacggg tagcacctcc
    26401 tttcccgcgc cctcccggtc tggccgggag gacgcggagg cgattagtta agggtttgga
    26461 cagggacaaa ggccaggatc agcccagcag cccggacagc aggggaacca gagtgacacc
    26521 gatcagggcc acgccgccgc cagcgacaag ctgcttgaca ccctgcgatt ttgcccccgg
    26581 attgtcctgc ccgtatccct ccaacagatt gatgccgccc catacgcaca gagcgccgcc
    26641 cagtccgatc acgatagtct gcaaagtagt aactgcggaa ttaaaaaatg ccataaattt
    26701 acctctttct gccggtttcc ggctcataat gattttttga ttttgttgtt ggaatgaaaa
    26761 aagccgctgt ttattcagcg gcggcgtcct cgtccgacag gtcgatttca tacaggtcga
    26821 atacttcatc ctgcgttacc acttgctgcc gtttccggcg cgtgatagtc aaaaatctgt
    26881 ccacgtcaaa ggtattcttc ttgtcggcgt cggcaaggta tttgtaccgg ggatgcttgg
    26941 taatatcgaa tttctccgat aaaaacgggc gcacaccccg tagctgcaag atacacttgc
    27001 cgccgtccat cacggcaatt tcgtcttggg acatcaactc ctttcctaat ttttgatagt
    27061 tcaatccgtg ggacgtttgg cttccccggt tctcgctggt gttgaaactg tcaatcgttt
    27121 ctttccccag cgcatcggaa atctccttgg catttttgcc gcgcccacta aggaaaagca
    27181 cactatcgca gttatccgaa atgatctcgg cggcgtcctt gtaaatcgct tttagctgcg
    27241 actggctctg caaaataata gaggccgata tttcacggct tcgaatggtg gcaatgagtt
    27301 tatcgaaatt gggtatttgg ccaatgttgg caaattcatc caaaatcagg cgtacatgga
    27361 caggcagccg cccgccgtac acatcatcag cccggtcaca aagcaggttg attagctggc
    27421 tttggagcat agccagaatg aaattaaagg tcgtgtccgt atcgctcata atgagataca
    27481 gcaccgtctt ttcgtccccg atggtgtcca gctccatttc gtcgtcctcc atcagctcgc
    27541 gtacctcccg gatgtcaaag ggcgcaagtc tggcaccgca tgaaatcagg atggaagaac
    27601 gggtcttgcc tgcggacagc aggaatttct tgtactggcg caccgcaaaa tggtcggggt
    27661 ctttctgctc caaacgctca aacatgagat cgacggggct ttgaaactcc gggtcgtcct
    27721 cgcgggcttc actggcgttt atcatttcca gcagcgttga gaagttcatt tcctccgctg
    27781 gggcctcgta ccagatatag ccgatcaggg ccgaataaaa caaccgttcc gacttcaccc
    27841 aaaaatcctc cgctgacttt tccccctcgc ccttggtgtt ggaaatcagg gtatttacca
    27901 gctttagcac gtccttttcc gaatggatgt agacaaaggg gttgtacttc atggacttgg
    27961 aaaagttaat ggtattcagg attttaatgc ggtagcccgc ctgctggaac atcctgccgg
    28021 tttccagaac caaagtgcct ttcggatctg tcaccacaaa cgaagtcgga tagtccgtgg
    28081 tcggaaagca ttgcatcagg ttgggtttca cgaaaaatct cgttttccct gaaccgctgc
    28141 caccgatcac cagcacgttt ttattccgcg ctgtcttggg gtctttgggc ctgccggtca
    28201 tggtaagccg ttccgtttgg gtgagcagga tattattttc aaacttgggg tcgatgtaag
    28261 gcgctatgtc tttggccgtc ccccagcggg cgctgccata ctccatgcct ttgcggtatt
    28321 tcttcacgtt cttgctcttg cagtacacca ccagccgcac gatcacggca ccggcgatac
    28381 cgatacacag gtcaaacagg tgcaggcttg gcagcgggtt ggcaaaagcc gccgcaaaac
    28441 catccgcaaa atgcaggagc ttccccgaca ggtcagcacc agcggccagc cggtacgcct
    28501 ccccgcattt cgcaaacagg tacacaaaaa tcagatacgg gaggttcagg atcagcaatt
    28561 tctttacgtc aggcttcaca gttccagccc cctttccttg attttctcct tggcccgctg
    28621 cttggtctgg gccgccgcct tttgcttcac agcggacaaa accttgcgga tagagggccg
    28681 ctgctccttg gaaagcgtct tggcggtaaa ctcccgaaac gccagatcaa ggttatctgc
    28741 atccttggcc ttgaaaatca caacgtagtg gggcggctgg gtggtcttat cttttcgtaa
    28801 ggtaaaatcc acgccgtatt tcttggcgca tggcttgaac gctccaatgt tggcctcggt
    28861 gatctcaatg ttggagagat cagccccatg ctttttaagc tgctttaggc tctgctggcc
    28921 gtggtgcagc gtgtttttgc ccttggcccg gtgttgcagg tactttttca gcgccgcttg
    28981 cagcacttga gccgtgagct tgcccgtttt catggacagg gcaatggtct tttgagtaac
    29041 ttcttcctgc aatcgcatcc ctccttgtca gaaagtcaaa agcggcgtct aaggcggaac
    29101 caccagacgc cgcaggtaga tataggtcaa atccgcaccc gcaggccgga aaggtcgtcg
    29161 gcccggatgc cgacaagata ccagttttcg gccatttcaa tgcgggtggg cctccatttg
    29221 ccgccgatca tcacgtcgaa acactccccg caatgcaggc cgccgtaata gtcggccaga
    29281 tcaaagcgga tgtcgtaacg gtctgttcgc tcgtcaaaaa tcaatgcgcc ctgcttcata
    29341 gggtcgtcct ccttttctcg ttacaggctt tcgccctcgc cgcaggaata gtccggcagg
    29401 ccggatttag gctttcccca atcgggctgt gccatgtcgt gcgcgacaag ggccgtgtag
    29461 tagttggaaa tggtgctggg ggcgttgaac agcatagccc gcaggtattg tttgatattg
    29521 cggactttcg ttgtgttctc ccgcagacag tcaaggacaa agcggatatg ttcgccggtc
    29581 agcttcatgt acttggattt caccagctcg gcagggtagt cgtccccggc gacacggatt
    29641 gtctttcggg cggtgcagac ggtttccagc atcaggtcta cgatttcgtc aagctgttca
    29701 cggtcaatgc tcctgtcctg aatgagatag gcatactcga tgttctccaa aatgatttcc
    29761 cgataaatcc gtacagcctc atcctttcct gtccttttcc gttccggcgg cgtagccgct
    29821 gcctcgccct ccataggggc aggggtcggg gatgggatag gaatggaatg ggtactttgt
    29881 ccatctgtaa ttattttttc tttttttgat aagtcagttc tttgtacttc tttatttaat
    29941 tgcgttggat tttccgacgc cggattatcc gatgtcggat tttccaacac cgggttatcc
    30001 gatgttggat tttccaatac cgggttttcc aataccggct gttcgtagat ggtatagacc
    30061 atatcggcca ttttgccttt tgcgtcacgg ccctgctcac gccggatata tccagctttt
    30121 tcaagctccc ataccgctgt cctgatcgcg tcgatgcttt cccggttgat ataggacagt
    30181 ccttttaggg tatagtccca atcctccggc aaggacaaca tctgcgacag caggcccttg
    30241 gcctttaagg tcaggttctt attccgcagg tggtgatttg acatcaccgt atagcctttg
    30301 ttcttttcca cacggaaaac tgccatagcg ttgttcgctc ctttcactgt gaatttgacc
    30361 gctgcatagt cggtcagctt gcccggctga tagggacact ctgcaaactg gcagaattga
    30421 tatttccaat ccgggcggta aaatcggcag gtgccgcaat cctccggcgc gtccgccccg
    30481 ccgccgtcgt agtgatcgaa accgggcttt tcctgcatca gccgttcaaa cgcccggtca
    30541 gggccggaag taaatagcat ggcgtcgcct cctttctcta tttgggcata aaaaagcggc
    30601 gtcctgttct cccatgacgg gaaagaggaa cgccgcgttt acggtgtcgt attcaattta
    30661 tgatgtgccg tatttggggt ggcgggtatt agcagtatgg ttcagcatat atgcggctca
    30721 atccgaaagt agtaaattgg tagtaaattg agttctcata tcctgcgaaa tgcccgtatt
    30781 tccggggctt tcagcgataa cctaaatttt tggaataaaa ctttcattat aggctactgc
    30841 aacatccatc caatcagcaa tctctttttg gatctcaggt cgtttccagt agccaacgac
    30901 gattttattt tgtttattta atcgagcatt gatgaaccca tattcgcggt caccatgagc
    30961 ggattgattt aaattcatga aatccatatc gatcgttttc caaggaatgc tttcgttata
    31021 ttgcgtagct aaatgaagca atggtttttg tagaagcttt gtcccgcgga tccacatttt
    31081 tgctggtgag aaagtatgca tccaagtgat cacacctgct acttcttctc gataattgac
    31141 ctctttcatg atttttgtga tcgtatcagc agtaactgct aattcttgaa ggcggattgg
    31201 ataaggcaat tggccatttt cattcagttc atcgaccatt tcttgtgcat gtttctttac
    31261 ttctcgcagt gcttcttccc catataaatg ctgtgatcct acaacaaacc aaaattcttt
    31321 ttctccaata ttcaacataa ttagccactc cttttatttg ttttgtccgt aatacgcatt
    31381 ttttccgtgt tttcgtaaat aatgtttatc taaaatccgt tgaggcagct cttctgaaaa
    31441 tgaattgagc tgtctggtaa ataaattcat cttgcatact tcatctagta cgactgcgtt
    31501 cattaccgca ctttgcgcat ctttccccca agtaaatgga ccgtgtccgt gtaaaagtac
    31561 ccctggaatt gctaagggat caattttgcg ttctttgaat gtttctatga taacttttcc
    31621 tgtttcatat tcgtacccgc tgtcgatttc ctgttgtgtc aaaaatcgag cacaaggtac
    31681 cgatccataa aaagtatctg catgcgtcgt ccccatcgca ggaacatcca atcctgcttg
    31741 tgcccagatc gtcgcccatg tcgagtgagt atggacgatt cctccgattt gaggaaatga
    31801 acgatataaa acagcatgag taggcgtatc cgaagaggga ttgagtttac cttcaatgat
    31861 atgattgtcc aagtccacaa cgaccatgtc gtctgctgtc atctcttcat aactgactcc
    31921 gctaggtttg ataacgaaat atcgtgtttc aggatcaaaa gcgctcacat ttccccatgt
    31981 atatttgacg agtccgtgtt taggcaagtc aagatttgct tggtatactt cttctttcag
    32041 ttgttccagc attttctatc actccttttt cttgcaattg atgaatcgct gttttttcaa
    32101 tgtcgatccc ctcacggtaa cgtctcataa atatctgata gcctgctatt tcttctgctg
    32161 aaggtgtgat ggtgattcct tggtcttgtc caaacacgtc ttctgccaag aagttttcta
    32221 aagacttccc atgtcgatcc atcatatagg ctgctaataa cgcgattccc cacgctccac
    32281 cttctccggc tgtgtccatc actgtaactg gtgcctccat agcagatgct agaatccgct
    32341 gtccaacttc tggtgtttta aaaatccccc catgccccac taaacgatca atttggacat
    32401 tctcagattt caatatatcc attccgattc tcattgcacc aaaagcactg gctaaatgga
    32461 tccgcatgaa attcgctaaa tcaaaacggc tacctggtgt acgtacaaat aatggccttc
    32521 cttcatttac tcctgtaatg ttttcaccgg aaaaataacc ataagaaagt aatcccccgc
    32581 aatccgtatc gccttctagc gctttgttga ataataccgt gaataattta tctctgctta
    32641 tctccatacc caaagaattg gtaaattctt caaaaatact gacccaagca ttgatatccg
    32701 aagagcagtt attcgtatga accatgccta ctagttctcc tgaaggtgta gtgaccatgt
    32761 cgatttccgg atggacattt tctagttctt tttctaatac gatcatagcg aaggcggaag
    32821 taccagccga aatgttccct gtccgtttgg ctacactgtt cgtagcgacc ataccggttc
    32881 ctgcatcccc ttctggcgga caaaccggga ttcctggtct caaatttccc gtagggtcga
    32941 tcagataagc ccctgattcg cttaacttgc cagcttcttc tcctgctact agaactttag
    33001 gcaaaatgtg atccaagtca atcgctacgt gcgctttttc gattaactga ccaaaaatat
    33061 ttttcatttc ttgatggtag gttttcgttg aaggatcgat aggaaacatg cctgatgcat
    33121 ctcctacgcc tagtactttc tcaccagtaa gctgccaatg gacataacct gcaagcgttg
    33181 tcaaaaaatt aatttctttc acatgttctt ctttattcaa aatagattga tacaaatgag
    33241 cgatactcca tctctgcgga atattgtatt gaaatttttc cgttaatatt cgttctgctt
    33301 cttcagtgat tgtatttcgc caagtacgaa atggtactag taactgttcc ttgctatcaa
    33361 atgctagata accgtgcatc attgcactga acccaatcga cccgattgtc gtaagattct
    33421 cgccatagat ttcgaatact tctgctgcca tttttcggta actgacgcgc agtcctttcc
    33481 aaatatcttc taatgaatag gtccagatac cattttctag tttgttttcc cactcataac
    33541 taccagcggc aataggagta aaagatgaat caatcaatac agctttgatc ctagttgatc
    33601 caaactcaat ccctaaagat gtacgaccat ctatgacatc taacatactt tgcgcattta
    33661 cttccttcat aatgatttaa ctccctcctt ctcgtcaaac ctgatcaaac cgtcttttta
    33721 gtagcgctta caatgattat tgtatacttt tgtacgtaca tgtcaagcgg ttatttacaa
    33781 gaatacaata aaaaacactt gttttgtacg tacataagtt ataaaatgaa attgcttaca
    33841 aaatctgatc aaccgccttc tcgaaattct agaaggagag aatacttatg aaaaaagaaa
    33901 aaaaagtttc ctcatcgttt atttattttt ttggcgcatt tggcggcatt ctatttggat
    33961 atgatattgg tgttatgacc ggcgccttac cttttttaca gcatgattgg ggtttggcag
    34021 gtaaagcttc tttgatagga tggatcacgt cttcggtcat gttaggtgcg atccttggcg
    34081 gctctttatc tggtcttctt tctgataagc ttggacgacg aaaaatgatt cttctttctg
    34141 cacttatttt tatggctggt tctgtccttt ctgcatctgc ccctcacaat ggttcttatt
    34201 ttctgattgc agcaaggatt cttctaggtt tagctgttgg cgctgcatct gccctagttc
    34261 ctgcttatat gtctgaaatg gctcctgcta gactaagggg aagattgtca gggatcaatc
    34321 aagtgatgat tgcttctggc atgctccttt cctatgttgc agattatttg ctaaaagtgt
    34381 tgcctgaaac gatggcttgg cgcgtgatgt tagggctcgc tgctgtcccc gcgctgattt
    34441 tatttttcgg tgttttagct ctaccagagt caccgcgttt tcttatgcaa tctggccgct
    34501 tggaagaggc aaaaagagta ttgaactata ttcggacacc aaaagaagct gaacaggaat
    34561 tcgaacaaat ccagctgaat gtcaaacaag aaaagacaac cggaacttct tggcatactt
    34621 tgtttttaga aaaatatcgt tccttagtca ttgccggtat tggtgtagca gtattccagc
    34681 aatttcaagg agctaatgct attttttact atattccgct gatcgtagaa aaagcgactg
    34741 ggcatgcagc gagcgatgca ttgatgtggc cgatcatcca aggaatcatt ttagttgctg
    34801 gttctttgct ctttttggtt attgcagaca agttcaatcg gcgaacttta ttgaaaatag
    34861 gcggtagcgt gatgggactt tcattcatcc taccagctgt tttaggaact gtactggatg
    34921 ctcatacaaa ttcgttgttg attctcttgt ttttatgtat ttatgtcgca ttttattctt
    34981 gcacatgggc tccactgaca tgggtaatca taggcgaaat attcccacta gctgtccgcg
    35041 ggcgagcatc tggcctagcc tcttctttta attggattgg ttctttccta gttggcttgc
    35101 tttttcctgt gatgactgct tctatgtctc aagaaatcgt tttcggcatt tttgggatca
    35161 tctgcttttt aggggtttta tttattcaag agatcgtacc agaaactcgt gggaaatctt
    35221 tagaggaaat cgaacaaagt gcatctaaaa aaacttatcc taaacgtatt tctatccatc
    35281 attcttaaag aggttgtgac agaagtggtc agcttcaaga aataagaagg aaccgcttag
    35341 tttccagtca caaggaacaa tttcaaaaaa cagcttctca tgtttgatga atattgtgac
    35401 ttgtgaccag ttggtaggag aacaccgttt agtggagagg tggtgaaaga aacgttcagc
    35461 cttgagcgat gacaaaagct ctcacaaaca ttgcgacgag taaccgtagg agcaataaga
    35521 ggcggtaaaa acccgtctct tatttttcgt tttctttcac tgtttcccgt tcaactagta
    35581 caggttcata gagaatattt ggctgtgcct gtcctttttc aatcgttgtg acgatccacc
    35641 gtgcggcatc ttgtcccaac ttttcttttg gatgcgtcaa tgttgtcaat tttttattcc
    35701 ctaaatggct taaagaagaa tcgtctgttc ctacgatcga taggtcatct ggaatatgat
    35761 agccattttc tgtcaactta tctagcatta aactagctat ttgatcgtta tagcaaatga
    35821 tgccatctaa agcttgttct tctttcaacc gttgtactgt tttttcagcg attgtttctc
    35881 gtgtttccgt ggtgaaagta atgatatctt ccgtcaaaaa acgcacatta tactgttcac
    35941 acgcgctgat aaaacctttc atcctgtatt ttccttgaag atcgtcgatt tttgtgatga
    36001 acaacagacg ctgatgtcct ttttttatca aatattctgc tgccataaaa ccgactttca
    36061 catcatctaa acaaatataa gaggcattta actcttcata agcagcattg atcatcacca
    36121 tcggaatgcc ttgttctctc aaagcaacat aaagtgctaa gtttgggtta tactgattac
    36181 ttttcgtagg ctcaacgatc aaaccatcta ccccataagc aatcattttc ttcaaacact
    36241 ctttctccaa ttcgtgatcg ttattcgtac tggctaaaag caatgaatac ccagattctc
    36301 gtaattcatt ttcgattcct cggataatcg acggaaaaat ataatcagag agatatgtgg
    36361 tgatgacacc gatcgttttt gttctgttca atggtgtttt ttctttctta tagctgtcat
    36421 ctacatatgt gcccgaccct ttttctttac gcagatagcc ctcatttacc aacacagcga
    36481 ttgcttgccg aatcgtatgt ctgctgacgt catatatttc ttgcagcttg aattctgagg
    36541 gaatggttgt atttacttcg tattcctcac gaaggatctt ttgttttatc tcttctgcaa
    36601 tatcttgata ttttgccatt tgccttgccc ctttttattt gtacgtacat atatcataac
    36661 gagtctgcaa ggtttattca agcaaaaatc aaggtttctt gtgctcataa ggcatacgga
    36721 acaggttcac caaattctgg aaatccttgc tcattccacg taaagcattg cgcgttcgcg
    36781 tgccgattag gattgtctaa cggatcccct ttttggttct tctctggtcg agcatgatag
    36841 atcaaaatat caaagcaccc gtcttctgaa accgtaaacg agttgtgacc aggaccaaat
    36901 tgcttatttt tttcagaaga aacgaatact ggctccgata atttatgcca tgattctttt
    36961 aataaaagat tcttgtgctc atcagcccac agcaggccca tggcatagtt ttcatctgtt
    37021 gcactaccag aatacgtaat gaatattttc ccattgcgag taaggactgc tggaccttca
    37081 tttactgaaa aaccccgttt ttcccattca tactcaggta tagaaaggag gatctgcttc
    37141 ccctttaacg tccaaggatt atccatttcg gatagataaa gattagaatt cccagtaatt
    37201 tcaggatctt gttgggccca cacataatat agctttcctt gagaagagaa agttgttccg
    37261 tctaaactga aagtttccct tttcgttttt atttgtccct tttctatcca atctgtattc
    37321 attggatcta tatgctgatt ttcaagtacg aacatgcggt gatgatgaga ttcatcacgt
    37381 atagttttat gattgcttgc agcaaagtaa atataccatt ttccattgat ataatggact
    37441 tcaggtgccc agatcaattc actcatcggt ccttcttcat gagcctgcca tacaatcagg
    37501 cttgcagcat gttctaattc attcagtgac tttgcccttc ttaattcaat cacttggtag
    37561 cctggaaccg atcctgtaaa ataataataa ccatctgtat gtttatatac ccaaggatct
    37621 gcccgttgcc gaacgatagg attattataa agtgtcttca tcataacaaa tttcctcaca
    37681 ttttctttat tctaattaca ttccaagagt atttttctat ccctacattt aattcgtcat
    37741 gtttttctat tgaaaaatag tttatttcag gttttatttt ttctggttct tcacgtgtat
    37801 ttttgtccaa cagatcgcta ctggttaatg tgtagtgctc tccttgatct agcaaattga
    37861 aatcatgttc aatcgttatc ttttgttgtt catttgtgcg attgatcaag aaaatagtca
    37921 gctgattgcc gttatctacg atcacactgt ccacataagg aacatttttt atcttttcac
    37981 aatcataaac agggcaaatg atttgttgtt tcaatacttg acctttagca tatttcgata
    38041 agtgttgcat cacataataa gttggattcc tccatgcttg tcctttagca tctgtcagta
    38101 ttaaaggtat tgtgtttact aacaatgatt gacaactaat ctttacgcga tctgcgtgtc
    38161 gtaaaatagc cagccctaat gaaccaaata ataatgtatc ttccatagta aagtaacacc
    38221 aatcgatggg actaccgact tcaaaatccc tatgtctttt ttccggttgg gcatgtacat
    38281 tccattcatc aaacgctaga tacattgttt tctcacttct caaatatcct tttacataat
    38341 cacaagtagc aacgatttct tcaatttgac gatcgaatcg ataagctttt gcaaggtatg
    38401 tcgctgtatc atcacgctca tttttaggag gtttagtcaa gtcttcttca tcatacttat
    38461 caatatagtt atgcaaagct aaataatcta cattctcata agcttcttct aatgcgatac
    38521 gatcccattc agggtacgat ggtaaacgtg gcgtagagct tccaactaag attgtttcaa
    38581 ttgaatcatc cactaacttc atgacttttg aggcttcatt tgctaaccta ccatattcat
    38641 aagcactctt agcccccact tgccatggac cgtctagctc attccctaaa caccataatt
    38701 taacgccaaa aggctttttt tgcccatttt ttattcttaa atcactccag aaggttcctt
    38761 ttggaaaatt acaatattct actaaatttt ttgcttcatc aattcctttt gttcctaaat
    38821 tcaccgtgaa tatcggtttc gcttgtacat gactgatcca tttaaaaaat tcgtggagtc
    38881 caaaagaatt tggttctata cctcgccatg ctaaatcaat tttttttggt cgttgttctt
    38941 tcctacctac agtatccacc caatcataac cagatgtaaa gtttcctcca ggatagcgaa
    39001 tgacacctaa ttctaattcc tttacataag agaggacatc ttgtctaaac ccgtcaccat
    39061 cagctgtttc atggcccggt tcataaatcc ctgtatagac gacacttccc atatgctcaa
    39121 caaatgagcc aaacagccga gaactgatct ctcctaccgt aaaatcctct ctgattttta
    39181 ctttcacttc ttcgtccaac agctttccct acctttcatt tcctatagtc aagataatag
    39241 atacaagttt ccatacgcca ccagcaaaga taaaaataaa aggagggaaa agaaatatga
    39301 gcagtacaaa tcctaataac aatacgcaac aaagaatatt tctcaaaaaa tcaaaaaata
    39361 ctttccatgc actttgttca aaaatttgta aaaatgtgat atctttgttt tcagaaatca
    39421 catatatcca ggataaaaga aacatggaat aaataagtaa aactacatat ccactaattg
    39481 aaagtacgat tgtctgttct tctaataatt gattaacaag aaaataaata atgatcgtta
    39541 acagactaag gaacaagttc ttaccaaaat gttgctttat tccttgaaag aaaaaataaa
    39601 tgatatttcc tgatccctca cctttccatt gcgccattac ataaaaaaca gcacatgtag
    39661 caggcacgat agtaataaca ggcaaacaca cgattaccca gagaatacct aataagatgt
    39721 aatcagaaac cacaatcaac tgtccataaa atttagtctc aactattttc atcttcctca
    39781 ctctttcatt ccagacatag ctgttccttg aacaaaatat ttctgtgcaa aaatataaac
    39841 cactagtaat ggcagcattg aaataaccgt tccagccatt acaggtccat aaaaagaaat
    39901 gttctgccct gtaaataaag ctaaccctgc tggtaaagtt ctcatttttg aactacttgt
    39961 caatatcaat ggataaagca agtcattcca actattcatc agcgtgaaaa tccctaatga
    40021 taaaagagta ggtttgctca atggcaacat gattttcaaa aaaatattaa actcacttaa
    40081 tccatcaatg cgtgctgcct cttccaaaga atctggtaaa gtaataaaaa aggaacgcat
    40141 catgaagata ccaaatgcag ttgtcatacg aggaatgatc aaacctgcat aagtatcaag
    40201 catgccaagc aaattgactt caataaatag aggaatcatg aagacttgga atgggatcat
    40261 cattgtcagc aaaacgaaat agaacaaaac tgattttcct ttgaaacgca tacgagcaaa
    40321 tgcatacccc gcaagagaat caaagaatac agaagtgatc actgtccctc cagcaaaaat
    40381 cactgtattt ttgatgtaat ctaataaagg gatcgttgtc caaaccttaa tatagttatc
    40441 tagggtatag ctatctgcaa atattctagg cggaaatgag ataatgtctt tttcgtgttt
    40501 aaaagaagaa ataatcagcc acaaaaaagg aaacgcaata accaacaata taactagcat
    40561 actaatcgtt cgaatgattt ttttaccact aactgctttt cgactattca cagtaactgt
    40621 aatcgagctt tctggtgcca tacaggtttc cctcctattt catttgtttt tctttccgtg
    40681 acatgtacac attagtggag atagctatag ttgcaacaat gataaacaaa accgaagaca
    40741 gtgctgatgc atagcccaat tcataaggtg ctgtaaatcc tcgactgtaa atatattgaa
    40801 cagctgtttc tgtcttaaat tgtgggccac cagcggttgc aacatatact tggtcaaaca
    40861 cttgcatcga accaatcaga ttcgttaaaa tacaaaaacc taaggaggga acgatctgag
    40921 gtagcgtaat gttaaaaaac tgctgtcgat ttgttgcacc atccatttga gcagattcat
    40981 acaaagaggg agagattccc tgaatagcag tcaagagaat cgtcatagta acaccaaaat
    41041 tcttccaaac agtcatgatg gctaccgtcg gcatagcaag ggttggatcg cgaaaaaatt
    41101 gagggatcgg caagccgact tgtgaaaaca agtaaggaat cgcccctaca ttcggatcaa
    41161 gcaacataga aaaaataatc gcaattgacg tcaatgaaca aataactgga atgtaaaatg
    41221 tcgaacgaca aaaacgattg aatctggtat ttttagataa tgctactgct gctaataaac
    41281 caacgataat ttgtgttggc gtttcgagta cggtgaaata taaagaatga atcaacgaat
    41341 taactgctcg ttcatcacta aatatacgtg tgaaattttc aaaacttaca aaatttcttg
    41401 atgtaaagaa aatattcaaa tctgtaaaac taatagcaaa tgttcctaaa agcggtatga
    41461 cagtaaataa taataaaact aaaaaagatg gagttaaaaa caaatacgca gcacgatcag
    41521 gacgattcca atatttggtg aatccgttca tatagtccac ctcatctttc attttgataa
    41581 aatatacaat cttggtttaa acgaatctga ataagatatc cgaacaatcg ctgtgatttt
    41641 tgcaataaca cctatctgca aatactaggt cgatcattca gatatctgta tcttgccaac
    41701 agtctatcct gtataaagtt ctgtactatt tttgcagtaa ttgattgatg gcatcatctg
    41761 catcgttcat gagtgtctca ggatcttctc ctgctaataa tttttcaatc agtggattga
    41821 tgatatcgtt attgatcgca gagatttggg taaaacctgg taaatatggc tctgcatagt
    41881 ccatttgttt cgataattca gatacaatag gatcattttt tacttcttca tcttttgcta
    41941 ctgaatccaa gtaggcagga aaaccatttt cgatactcca ttttttacca atttcagttg
    42001 tattccaata tttcaaaaac tcatagacag cttctttttt attattatct gtacttgccg
    42061 gaatggcata tcctacgcca tctaaaatag ctgttttttt gtctgaatca ctcccttgtg
    42121 gtaaggtagt cacattataa tcaatctcgt ttgctttcaa tccgttattt aaccatggcc
    42181 cattgatttc aatggctagt tgaccagcat tcattaaatt gtccatttcg gcgccagaaa
    42241 tcgattctgg accagtcttg tctacatgga tcattttttg gatcgctttt aacgttttaa
    42301 ggttctcagg agacgcaaat tcagacttag tataatcatc gttcactaat ttaccgccat
    42361 ttgctaacat ccagttatat aacggtgcag ttccatcctt attgaagaca aaacctgata
    42421 catttttact actatcagtt aattttggtg ccatttctgt caattcttcc caagtagtag
    42481 gtggttgttc agtatctaat ccagcttgtt taaacaaatc attattccaa tacatataca
    42541 tgccttgtac ctgcatgggg acaaaatact gtttaccttc tacttcacct aattcaatag
    42601 ccgtttcttt aaaatcagat ttatctactc catcatattc ccagaaatcg tctaatggtt
    42661 gtaccgctcc gttttctaca tactgtgcaa aatctggata atttaatgca ataaagtcag
    42721 gtgctttttt agaagaaatc gctgtaggaa gtttttcatt caaattggcc caagtcatga
    42781 tatccatttc aattttgatg tttttatcat ttgttttatt aaattcatta acgatttctt
    42841 gcaatatttc accatcagat gcagtaaacc cattccaaaa agtcaaagtc acttctttat
    42901 cagaatcaga ttctgctgaa cttccgccac cgcaagctcc taaaatacct gttgcagcta
    42961 ccaacaaaga gccaattaac cattttttac ctttcatttt ttgttcctcc ttcatctgat
    43021 aaacgacatc tgaccacatt ccaagatagc ggtttcaata aacaattgat tttcccatct
    43081 tcagctttta catttgttga atgacttggt tttacttgtt cacttttagg aagattagtt
    43141 gcttttgtat caaatccact catttcagaa aaatcaatca ctccctctaa tgataattca
    43201 gacaagtgaa cagttagatt catttcttct tctccacggt taactgcaaa tatgacaagt
    43261 tctttgtcat ttattacggc tatactttct aaatacggca cttcttcaaa atcttccgtc
    43321 gcatagtttg ctgaacgaat ttgtgggctt aacacctctc cttgtccata cacagcagct
    43381 tgcataaatg gataatagat cgtctgtctc caagcttctc cgtttgtttc tgtcctgatt
    43441 ggtgcaataa cgtttaccaa ttgagcaaga caagcaatct ttactctatc tgcatgtttc
    43501 aataaagtga ttaatagaca gcctaatagt aatgcatctt caaaattata gttatcttct
    43561 agtaaaggag gagcaatctg ccaaggcgct gcttgctcat cttgttccgc tgaatgatac
    43621 caaatattcc attcatcaaa ggacaggttg atctgcttct tactatgttt cttcgccttg
    43681 actgtatcgc acatcgctgt cacttcagaa atgaaccgat ccatgtctaa ggaacgtgca
    43741 agataatgag aaagatcatt tttttggttg ccataatatt gatgcagaga caaataatct
    43801 atttgatcgt acgcttgatc aagaactgtt aactcccaat caccaaatgt aggcatttgc
    43861 cgattcgaac ttccgcataa aaccacctca attgaatcat ctacgagttt catcgcctta
    43921 gccgtttcct ctgctaaccg tccatattct tccgctgttt tatgtccaat ctgccaagga
    43981 ccgtccattt cattccctaa acaccatgtc ttaattccaa aagggctctc ttgaccattc
    44041 gaacgcctta aatcactcca ataagttcct ttaggaaaat tacaatattc gactaaatta
    44101 cgagctgcat ctactccacg agtacccaga ttgacagcca tattgatttc ggcccccaca
    44161 tgctgacacc agttataaaa ttcatgaatc ccaacttcat tcgtttcaat tgtccgccaa
    44221 gctaaatcca accttctagg tctatttgct atgggcccaa tactgtcttc ccaacgaaat
    44281 cctgacacaa aatttccacc aggatatcta atcatgggaa tgttcaattc ttttaccaag
    44341 tgaatgacgt cttggcgaaa tccactttta ttagctgatg gatgatctgg ctgataaatc
    44401 ccttcatata ctgctcgtcc catatgttca ataaatgaac tgtacaaccg cggatcaact
    44461 ttgcctacac gcttgacact actaatcaac attgtggctt ccataactga cctcctttaa
    44521 tttatacatg aataatacac ctcgttgaaa gcgttgtcaa taatataaat gttaaactta
    44581 cttatttttt atcgatttta attaaccaaa atattaataa tgattaaaac aaataattta
    44641 atataacttt tattaacaaa tatgttaata tataagaaaa accttttaag aggtgatata
    44701 tatgcaacta caaataaacg aagaatcctt accggtatat gaagcattag ctagtaaaac
    44761 aaggatcaag atcatccagc tactttccaa aaaaaagatg aatgtcaaag atttggcaaa
    44821 agaacttgga gtgagcagtg ctatcacgac gatgcacgtg aaaaagctag aggaagcaaa
    44881 catcatcaaa acagaaaaag taggacaaca aaaaatttcg agccttcgtg tcgataaaat
    44941 cgatattagt tttccagaaa aaatattcaa tgcttttgat acgaaagaaa catcgatacc
    45001 tattggtcac tatacaaatt atgcaattga accaacatgc ggtttagcta cgatccatga
    45061 ttttatcggg aaagtggatg aaccacgcta ttttatggat cctcgaagga tggatgcccg
    45121 cattctctgg tttaccagcg gatttgtcga gtatcaggca cctaattttt taaatacaga
    45181 ggatacattg gagatgttgg aagtttctgt ggaaatttct tctgaatttc ctttttcaaa
    45241 tgacaattgg ccttcagata tcactttcag cctaaatggt gtggagctag gaacatggac
    45301 gagccctgga gattttgctg atatccgcgg taaatatacg cctgattggt atccagataa
    45361 tcttaatcaa tacggcttgc tgaagacgat ccgaattacc aaacacttga cgaatatgaa
    45421 tggagaaccc ttgtcaaaca tcacgatcaa cgacatccct aaagagcaag acacttggca
    45481 tttgcgaatc gaagtgaaag acgatgccaa acatgtgggg ggctgtactt tatttggtaa
    45541 aggattcggt aattacgatc aggatatcaa attaaaagtt tactacagct gatatttttc
    45601 ttttctattt tataaaacaa aaacagccaa tccctatgaa gggacggctg tttttgcttt
    45661 attgttattt ccagaaatca tccaaaacgg aaattggcaa atgtcgttta tgttgtgtct
    45721 tgttccacca tgcttcgatt ttttcttgtg cttgagcggg aacttctttt ccttctagat
    45781 aatcatcaat ttcattatat gtgacaccta gtgcgacttc atctgcaatc attggtttcc
    45841 catcttcaag atctgcagtc ggaatttttg tgtataattt ttccggtgca ttcaatgctt
    45901 gaagcaattg tttcccttgt cgtttgtcca aacggaataa tggcaaaatg tcggctccac
    45961 catcaccaaa tttcgtgaag aatccagtaa tgttttctgc agcatgatct gtccctaata
    46021 cggctcctgc tctttctcca gctacggcat attgcgtaat catacgttga cgtgctttga
    46081 tatttccttt gttaaaatcg ctgattccca cacctgcttc gcttaatact tgtacttgtg
    46141 catcaacagc tggtttgata tttactcgca gactaacatc gggctggata aagtcaagag
    46201 cagcttttgc atcttcttca tctgcttgtt caccataagg aagacgaaca gcgataaatt
    46261 gatagttttc atcttttgtt tcttcacgca tttcttccat cgttagttgc gccaaacggc
    46321 ctgctaaagt agaatcttgg ccgccgctga tacctagtac aaaagtttta agaaacggat
    46381 attttttcaa atatgctttc ataaagtcaa tacttttacg tatttcttct tttggatcaa
    46441 ttgttggttt gacacctaat tcattgataa tttctgtctg caggctcatt tattctcctc
    46501 ctatgcttct gtatgaagtt ctgctacgct ttttttcatt cgttccatga tagccatttt
    46561 atggttccag cattcagtag acagatcgac tgggtatttt tgcggattca agtctcgttt
    46621 atactcttcc catagtgaat ctagattttc ttttgtatat tctttgattt cgtttagtgc
    46681 aggtaattcg taaactcttt ttccttcgat aaagatatct tgtaaaactg ggcgagctgt
    46741 aaagtctcga acagttttat tgataaacgt atgcactgga tggaacatga agatagcttc
    46801 ttcttctcga gggtcttcat cccataatgt cacgtagtct ccttcagatt tcccatcaaa
    46861 atttcgagtg atgcgccaca cttgtttttt ccctggagta gttacttttt ctgcattgct
    46921 tgataacttg atcgtatcca tcatttttcc ttcatcatct tcgatcgata ctagcttgaa
    46981 tactgcacca agggctggct gatcataggc tgtgatcaat tttgtcccaa caccccatac
    47041 atcaatttta gctttttgca tctttaaatt caaaatcgtt gcttcatcca agtcattcga
    47101 agcatagatt tttgcttccg taaatccggc tgcatctaat tgttcccgaa cacgcttaga
    47161 tatataggcc atatctccac tgtcgatgcg tacgccttgg aagttgattt tgtcacctaa
    47221 ttctttcgcc acgcgaatcg cacttggcac acctgatttc aacgtatcat aagtgtcgac
    47281 taagaacacg cagtctttat gggttttagc gtaggccata aatgcttcat aatcatttcc
    47341 ataagattgg actaacgaat gagcatgggt cccgctagct ggtatcccaa atatcttccc
    47401 agcacgtaca ttgcttgttg catctgctcc gccgatatat gccgctctag ttccccagac
    47461 tgctgcatcc agttcttgtg cccgtctagt tccaaattcc aatagtggat cttctccgat
    47521 gacagatttg atacgagctg cttttgtcgc gatcaacgtt tggaaattga ccatattcaa
    47581 cagtgctgtt tctactaatt ggcagtgcgc taaaggccct tccacttgga tcaatggttc
    47641 atttgcaaaa actagttctc cttcacgagc agaacgaact gttgctttaa attcaaaatt
    47701 ttgtaaatac tccaaaaaac cttcaggata gacttctaat ccacgcaagt aagcaatatc
    47761 ggaatcattg aacgtcagat tctctaaata attgactaac cgttccaatc ctgcaaaaac
    47821 cgcgtatccg tggttaaaag gcatttctcg aaagtaacat tcaaaaacag catgtaaatc
    47881 agctcgacct aattcccagt atgtctgcat catattgatt tgatatagat ccgtatgcag
    47941 cgtcaaactg tcgtctgggt aagtattatt catcttgtat tactcctctt ggcaagtttt
    48001 catttcctac ccattataac aaaaaaaatt aataggaaaa gaaatcttcc attttttctg
    48061 aaaaagcaca tgttttacgg atatttcttg ctaaaaatga actccatctg ctaaaactat
    48121 cctttcttat tggtatttaa cctaaacgag aaagaatact tattttattc aatgtatccg
    48181 agacacgaag aaattagcgt tttctatttt tcttacttga taaaataagt agattttcct
    48241 actacaatcg tagccgttaa gataccgatg attgaacaaa tataaccaaa tgtctctaca
    48301 acataatcaa tggcaaaagt ttttgaagca ataatacgtc tttccttttt tgcttcttat
    48361 ccccaaagaa acggatataa cttattatgt attgaatttt tttggaaagg cgaattatga
    48421 caagatatac cttgcgttga aaaaactcgc ggaaaaaata tcacacgttt ttaaaaagat
    48481 acaaagtaag aaagcagctg tcaatagaat ggaaacaaaa atggcgagac atcaatcagt
    48541 ctcgccttgt tttttattgt atacattaga tatggagcag gttaccataa agatgattat
    48601 tagtcgttat taaatagaat ccttcgtatt tttttgttct atcactacaa tatctttatt
    48661 tggacgtttg aattgtattc cggcacgttc tagctcctgt ttcactccta catggacttt
    48721 gacatcttct cgtgtcattt ttaaaacgtg atgaatcgca tagtcgattt cttgccttgt
    48781 gatttttttc ttcgtattga tcatcacgac ttgcttttta tcatatgtgt ctaccaatag
    48841 cagttgtgtt cgatctaacg aaaataattt gtaataatta atagccgtat tcccaaaaaa
    48901 gaattccact actttaggat aaaatgtctt aatatttaaa ttactattca caggtgtttc
    48961 gattagcttc atctcattcc tcttttctat atagtcgatt tagatccaat cttaagttat
    49021 gttaccatct ttcctagcat taaggaatcg gttacaattg aacctttaaa gacaaaagga
    49081 tttacctttt atcacttaat agtataacat aatttcatga gaaaaaaata caattttttc
    49141 ttgaccatct cgttacgtaa aggattatgc ttacatttgt caggaggaaa aataatggag
    49201 tacacaataa agaaaatgtc agagatatca ggagtcagtc cgagaacctt gcgcttttat
    49261 gatgagattg gactgctaaa accagctagg atcaattctt caggttatcg gatttatggc
    49321 aaaaaagaag tcgatcgtct gcaacacatc ttattttatc gaacaatggc attcaagttg
    49381 gatgatatcc aagaggtctt agacaatcca tcttttgacc accagaaagc tttaatcaag
    49441 catcagcaaa tgttgctgga aaaacgggca caaatcgata ccctcttgac aactgtccaa
    49501 cagacacttg atatgtacga aggaggaaga aaaatgagtg acaaagaaaa atttgaaggg
    49561 tttaaacaac aaaagttgaa agaaaatgaa gaatcctatg gacaagagat tcgacaaaaa
    49621 tacggaaaaa aaaaggttac agcatccaat gaaaaatgga tgaatatgga taaagaaacg
    49681 tatgaagaaa tgcaaactgt tgaaaagcag atgttatttg atctcactct ttacttaaaa
    49741 gaaccagaag atgaaagctt agcagaccgt atcttccaag ctcataagaa gtggttatct
    49801 tacagctggc ctgaatatca gccaaaagcg cataaaggac taggaatgat gtacgaagcc
    49861 gatgaacggt tcactgcata ttatgacgag cgaagtggtc atggtgcagc aaaagcttta
    49921 aatgaaatta tccaaaaaaa ggcgtaatct tttacatgat ccaacaaaaa agtacacgta
    49981 aaatgaccta ataacaaaac agcagacacc caagttagat ttttatgcta acttttggtg
    50041 tctgctccat tctttcacaa gttttttcat cctactttaa atatattcat cgttgaataa
    50101 acgtataagg tattttcact ttatcctttt tttctgtaag aaacaattga aatgccattt
    50161 ctccgcaagc ttccagatgg tggtcgatgg ttgggaaacc aagaagctcg ctgatcagca
    50221 aattatcgcg tccaatcacc actggtgtct tatcttgcag atagctttgc aagatgcctg
    50281 ctgcaaccat atccgaattt gtaaagacac catcaactcc aagctcttta aaaaagaagc
    50341 ctgcttgttt tcctttctct gcatctatac aatcccaaaa aacaagtgat tcatcaaaag
    50401 atggaaaaag ttgatgacat agctgcaaag tgatttttga gttataactt agcctgccac
    50461 ttcgccccaa cgtgatgccc aattgcttta taccttgctg cttcaaataa gtaagacctt
    50521 ctgtaattga ttgttctcga tcaataaaga cacagcttgc ctgttttccc ttgatttctt
    50581 cacaaaaaac tagaggtcca tatttttgat atgccaataa atcatctagt gtattggcac
    50641 gagacgtaat gatcaatcca tcgaaagctt tagctgcaaa ttcttcaaga taccttcgct
    50701 ctttttcttt ctgatagccc gtcggtaaaa gtgtcacttt gtaatcataa tcaaacgctg
    50761 cttcaatgat cccactgatc aactgatcaa aatacggatg attggtataa ggcagaatca
    50821 ctccaatgct tttcgttttt ccataactta actgtctggc atttgcatta gggatataat
    50881 cgacttcttt catgaccgca agtatttctt tccttttttc ctcatctaca tatggatgtc
    50941 cattgattac acgtgaaata gtagaaactg aataacctgt gagctttgcg atatctcgaa
    51001 tgtttgccac tgctgcttcg ccacctatac aaaaagattt tcttgtaaat agtctaccac
    51061 agctggaccg cattcaaaaa actgatacat ttttccttca tgcgaaaaac tgatccgctg
    51121 cccgccccaa tatatatctt ttgtcaaatt ttcgatttca ttcattggta tttcttttac
    51181 tatattccta ttcaaccctt gaaaactgta caacgttaat acggatccct tgaactcgac
    51241 aaacgcataa aaataattgt tcgttgtgcc atctgttatc tctacataag tattcattgc
    51301 aagccctcct tttgatactt tgagtatagt gtatgaaacg cgtctcatag caaggagttt
    51361 gttttgccaa agaaaagttt tattcctctt tcattattac caaagtctct tattttaaat
    51421 tgaatacatt ataatgatac tgtaaatata tctttattat tagtgaatgg atatttactt
    51481 ttaatagata aaatattata actattaaaa ataactattt tcattataat tacaca
//
LOCUS       DADGHT010000008        49594 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.008, whole genome shotgun sequence.
ACCESSION   DADGHT010000008 DADGHT010000000
VERSION     DADGHT010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.008"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            558..3197
                     /locus_tag="JX887_000400"
     CDS             558..3197
                     /locus_tag="JX887_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAX1256415.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3365..4063)
                     /locus_tag="JX887_000401"
     CDS             complement(3365..4063)
                     /locus_tag="JX887_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAX1256416.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            4281..5426
                     /gene="tgt"
                     /locus_tag="JX887_000402"
     CDS             4281..5426
                     /gene="tgt"
                     /locus_tag="JX887_000402"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAX1256417.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            5523..5903
                     /gene="yajC"
                     /locus_tag="JX887_000403"
     CDS             5523..5903
                     /gene="yajC"
                     /locus_tag="JX887_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAX1256418.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            6208..8805
                     /gene="adhE"
                     /locus_tag="JX887_000404"
                     /gene_synonym="adhC"
     CDS             6208..8805
                     /gene="adhE"
                     /locus_tag="JX887_000404"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAX1256419.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            9034..10140
                     /locus_tag="JX887_000405"
     CDS             9034..10140
                     /locus_tag="JX887_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAX1256420.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            10157..11185
                     /locus_tag="JX887_000406"
     CDS             10157..11185
                     /locus_tag="JX887_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAX1256421.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            11191..11670
                     /locus_tag="JX887_000407"
     CDS             11191..11670
                     /locus_tag="JX887_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAX1256422.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            11686..12981
                     /locus_tag="JX887_000408"
     CDS             11686..12981
                     /locus_tag="JX887_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAX1256423.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            12992..13816
                     /locus_tag="JX887_000409"
     CDS             12992..13816
                     /locus_tag="JX887_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAX1256424.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            13981..14880
                     /locus_tag="JX887_000410"
     CDS             13981..14880
                     /locus_tag="JX887_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAX1256425.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(15006..15875)
                     /locus_tag="JX887_000411"
     CDS             complement(15006..15875)
                     /locus_tag="JX887_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAX1256426.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            16028..17488
                     /gene="rhaB"
                     /locus_tag="JX887_000412"
     CDS             16028..17488
                     /gene="rhaB"
                     /locus_tag="JX887_000412"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAX1256427.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            17485..18741
                     /gene="rhaA"
                     /locus_tag="JX887_000413"
     CDS             17485..18741
                     /gene="rhaA"
                     /locus_tag="JX887_000413"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAX1256428.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            18755..19600
                     /gene="rhaD"
                     /locus_tag="JX887_000414"
     CDS             18755..19600
                     /gene="rhaD"
                     /locus_tag="JX887_000414"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAX1256429.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            19602..19913
                     /gene="rhaM"
                     /locus_tag="JX887_000415"
     CDS             19602..19913
                     /gene="rhaM"
                     /locus_tag="JX887_000415"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAX1256430.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            19995..21146
                     /gene="fucO"
                     /locus_tag="JX887_000416"
     CDS             19995..21146
                     /gene="fucO"
                     /locus_tag="JX887_000416"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAX1256431.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            21273..22031
                     /locus_tag="JX887_000417"
     CDS             21273..22031
                     /locus_tag="JX887_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAX1256432.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            22131..22775
                     /locus_tag="JX887_000418"
     CDS             22131..22775
                     /locus_tag="JX887_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAX1256433.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            22782..23789
                     /locus_tag="JX887_000419"
     CDS             22782..23789
                     /locus_tag="JX887_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAX1256434.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            23805..24647
                     /gene="kduI"
                     /locus_tag="JX887_000420"
     CDS             23805..24647
                     /gene="kduI"
                     /locus_tag="JX887_000420"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAX1256435.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            24667..25470
                     /locus_tag="JX887_000421"
     CDS             24667..25470
                     /locus_tag="JX887_000421"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAX1256436.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25719..26783)
                     /locus_tag="JX887_000422"
     CDS             complement(25719..26783)
                     /locus_tag="JX887_000422"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAX1256437.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26780..27865)
                     /locus_tag="JX887_000423"
     CDS             complement(26780..27865)
                     /locus_tag="JX887_000423"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAX1256438.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="JX887_000424"
     CDS             complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="JX887_000424"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAX1256439.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="JX887_000425"
     CDS             complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="JX887_000425"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAX1256440.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            30114..30767
                     /locus_tag="JX887_000426"
     CDS             30114..30767
                     /locus_tag="JX887_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAX1256441.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            30852..31757
                     /locus_tag="JX887_000427"
     CDS             30852..31757
                     /locus_tag="JX887_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAX1256442.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(31759..32391)
                     /locus_tag="JX887_000428"
     CDS             complement(31759..32391)
                     /locus_tag="JX887_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAX1256443.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            32711..33235
                     /gene="infC"
                     /locus_tag="JX887_000429"
     CDS             32711..33235
                     /gene="infC"
                     /locus_tag="JX887_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAX1256444.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            33307..33507
                     /gene="rpmI"
                     /locus_tag="JX887_000430"
     CDS             33307..33507
                     /gene="rpmI"
                     /locus_tag="JX887_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAX1256445.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            33560..33919
                     /gene="rplT"
                     /locus_tag="JX887_000431"
     CDS             33560..33919
                     /gene="rplT"
                     /locus_tag="JX887_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAX1256446.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            34171..35508
                     /locus_tag="JX887_000432"
     CDS             34171..35508
                     /locus_tag="JX887_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAX1256447.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            35556..37685
                     /locus_tag="JX887_000433"
     CDS             35556..37685
                     /locus_tag="JX887_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAX1256448.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            37660..38349
                     /locus_tag="JX887_000434"
     CDS             37660..38349
                     /locus_tag="JX887_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256449.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(38757..39370)
                     /locus_tag="JX887_000435"
                     /pseudo
     CDS             complement(38757..39370)
                     /locus_tag="JX887_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(39506..39700)
                     /locus_tag="JX887_000436"
     CDS             complement(39506..39700)
                     /locus_tag="JX887_000436"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256450.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(39750..40190)
                     /locus_tag="JX887_000437"
     CDS             complement(39750..40190)
                     /locus_tag="JX887_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAX1256451.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(40194..41039)
                     /locus_tag="JX887_000438"
     CDS             complement(40194..41039)
                     /locus_tag="JX887_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAX1256452.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            41188..42606
                     /gene="pepV"
                     /locus_tag="JX887_000439"
     CDS             41188..42606
                     /gene="pepV"
                     /locus_tag="JX887_000439"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAX1256453.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(42663..43610)
                     /locus_tag="JX887_000440"
     CDS             complement(42663..43610)
                     /locus_tag="JX887_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1256454.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(43833..44183)
                     /locus_tag="JX887_000441"
     CDS             complement(43833..44183)
                     /locus_tag="JX887_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAX1256455.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            44383..45462
                     /gene="pepA"
                     /locus_tag="JX887_000442"
     CDS             44383..45462
                     /gene="pepA"
                     /locus_tag="JX887_000442"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAX1256456.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            45606..45926
                     /locus_tag="JX887_000443"
     CDS             45606..45926
                     /locus_tag="JX887_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAX1256457.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            45948..46412
                     /locus_tag="JX887_000444"
     CDS             45948..46412
                     /locus_tag="JX887_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAX1256458.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            46617..47222
                     /locus_tag="JX887_000445"
     CDS             46617..47222
                     /locus_tag="JX887_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAX1256459.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(47261..48550)
                     /locus_tag="JX887_000446"
     CDS             complement(47261..48550)
                     /locus_tag="JX887_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAX1256460.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            48978..49457
                     /gene="rlmH"
                     /locus_tag="JX887_000447"
     CDS             48978..49457
                     /gene="rlmH"
                     /locus_tag="JX887_000447"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAX1256461.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
BASE COUNT        15706 a         9051 c        10638 g        14199 t
ORIGIN      
        1 aaaaagccga gctctcgata agctcggctt tcttgtacct cggaaggatt caaataaaca
       61 gaaatgattg taactttcca tcatacatgc aaagcacggt gttgaatttc ttcatgttaa
      121 acaaaaattt tgttttcgtt acatcttcaa catttgaaac atctcttgtt cctattcaat
      181 tttcagacgt ttacgttatt caattgttac gtatcgcatt acttcttgtt tcggatactt
      241 cgtgatccaa acatccatac gcattcacta tttataggtt tgtactctac acgcatgtct
      301 gggtgaaacc tgtacttcta acaactttgt ttgcttacac tgttctatcg agaaattctt
      361 ctgtctattt gatggtatcc tccttcctta catctatata atagcatcct ttggtagcgt
      421 ttgcaaatat aagcacttta aattttacgc tttcttaaca aataatcgat aagcccttta
      481 tttgaagtaa ataaaaaaag gatgttatag taaaataagt accttttttt gtacgaagat
      541 tttaaaggag gaataggatg gaagaataca agcagacaat agaagaagta aagaaggtaa
      601 cagaagcaga tccagatact gggttgtctt cacaagaagt ggatgaacgg cgaaaaaagc
      661 agggattgaa taaattcgat gaggcgccga aagaatcgat gatcaaaaaa ttctttcgaa
      721 gcttgtccga ttttacaacg atcatccttc ttgtagcagc ggtgatttcc ttttataccg
      781 catttgctac agaacatggg gatttatttg aaggactgct gatcatcgct atcgttgtga
      841 tcaactcggt attggcgatt gtccaagaag gaaacgcaga aaaagcactg gaatccttgc
      901 aagatatgaa taaacaaacg gcaactgtca tacgagacgg caaagtgacc actgttgagt
      961 cagagcaact ggtagtgggt gatattcttg ttttagagtc cggtgatgct atttctgccg
     1021 atgcccgttt gatcgaagca tcacaattac gtgtagaaga atcggcgttg actggagaaa
     1081 gtgaagcagt tgaaaaagat gcagcattta ttgctgaaga agatgagtca ttaggtgacc
     1141 aacttaatat ggtatttaaa ggatgtacgg ttgctgcagg tcgtgggaaa gcgatcgtca
     1201 ctgccattgg catggctaca gaaatgggta agatcgcgga tcttttgaac gaaaatacta
     1261 tgcaaaaaac acctttacag gtccgattga atcagctagg caaacgaatc agtatgatcg
     1321 ctttagcggc tgcggcttta gtatttgtga ttggtgaact gcaaggagaa ccactccttg
     1381 agatgttcat gacttcgatt tccttggctg ttgcagctgt accggaaacc ttgactgtta
     1441 ttgttacgtt gacacttgca tacggtgtgc agaagatggc gaggaaacat gcgatcatcc
     1501 gacagttgcc agcagttgaa acgctaggaa ccgctaatgt tatctgctca gacaaaacag
     1561 gaacgctgac acaaaatgaa atgcgcgtcc gccgggtatg gagcaaagaa gatgaagtaa
     1621 cgaatatcga agattcaatg acgaacagcg cgatggaaat attgaaaatg gctgcactat
     1681 gtacagatgt gacggtcgag caagaagatg acgaccttgt tatcaaaggt aatccaacag
     1741 aagtagccat cgtaagggct gttgaagaga attatcatac aaaggcagaa ttagaagaaa
     1801 aatatccacg agtaaacgag cttccttttg attctgaacg aaaaatgatg acaacagttc
     1861 accaaatggg cgaaaaatac atctcaatca ccaaaggagc attcgatgtt cttgctccgc
     1921 gctttagttc aggcgatgta gaacaagcgg cgatcgttaa tgatcgcttt ggtaaacggg
     1981 cactgagagt gattgctgtt ggttatgcta cttatgacga agaaccgcaa gatatttctt
     2041 ctgaagcact ggaaaaagac ttacgtttga ttggtctgat cggaatgatc gatccaccac
     2101 gtccagaaag taaaggagca atcaagcgag cgaaaaaggc tggcatcaaa acagtcatga
     2161 tcactggaga tcatgtggtg actgccagtg ccatagcgaa agaattaggt atcttgaatg
     2221 atccgtcaga agcactttca ggatcagaac tgcatcaatt atcagacgaa gaattagatg
     2281 cgcgtgtcaa agctctctct gtctatgctc gggtaacgcc agaagacaag atccggatcg
     2341 tcaaatcttg gcaacgtacg ggtgcagtcg tagcgatgac tggggatggt gtgaatgatg
     2401 caccagcgtt gaaagcaagt aacgttgggt gtgccatggg gatcacagga acagatgtgg
     2461 cgcaaagtgc cgcagatatg attttgacgg atgacaactt tgcgacgatc gtagacgctg
     2521 tcagtcaagg acgttcggtt tatcagaata ttcgtaaagc tatcaacttt ttgctaagct
     2581 gtaatatttc ggagatcttt attgttttga ttgcgatgct gttaggatgg ggagcaccat
     2641 ttacagctgt gcaactactg tttgtcaatg tagttgctga tggacttcca ggatttgctt
     2701 taggaagaga gccagcggaa cacggcatca tggatcagcc acccattccg aaaaatgaag
     2761 ggatctttgc tcgaggttta ttgcaaaaaa ttgccataaa tgcaggggtc ttcaccatcg
     2821 taaccttgtt tggttattat ttaggtagtt atgtcgatac tatcagccca tgggtagacg
     2881 caagtcagca tgtcggtcaa actgttgcat tcttgatctt agcttattca tcgattctgc
     2941 atgtgttcaa tgtacgcagc agccaatcga tcttcaaagt caatttagcg accaataaag
     3001 ctttggtaga aatggcgtta ctggcattag ctattacaac ggctgttgct ttgctgccat
     3061 ttacgcaaga actattcggc ctagtacaca tcagtttgaa tcactggttc ttggtaggga
     3121 ttttatctat cgtaccaatc gcggtgaatg aactgatcaa gttccatcga ttaccggaag
     3181 cagaagaaga ggaatgatta actgtttcta agttgatttt ctttttactg gaactataca
     3241 aaaaggaggt gtgacatgaa tgttgtcaca cctccttttt gctaatgggc tgaatgtttc
     3301 ttttactgcc tctcgataaa cggtgttctc ctgccacccc ctcggtcaca agtcacactc
     3361 tcttttaaat atcttttggc aattgttcat aaaatgctgc ttttgttgca gaaatgtatg
     3421 ggctgagcca tagataacca ataccagcag ttgctaatgc taagatatgc cagccgataa
     3481 atgaaagatc taaccagaaa agttgtcctt tataaccatc catcaatttt cgacttgcag
     3541 tgatcgtatc cagtacttta ggtgtttgtc ctgtttcttg gacgatatcg tagtaaataa
     3601 aatagctttg agaataagaa tagcttttaa tgattccagg aataactaat agcaaacccc
     3661 ataatgttgt aaagatcgag atcagcacag ctaagctgat cactccgccg ataaacaaac
     3721 ctttgaatcc acgaaatgca tctttgaatg gttcgatctg atctttttgt ccacgtaaaa
     3781 tatcaagata agtccaagaa ataccgctca tgaacaaagc gctaatgatg ctggaaataa
     3841 ttccgccacc gcctcctgaa ctaccgcctc ctgaagttgt cgcttctgag acgctcgctg
     3901 atccatcata tatggtggtg gcaaacaaga taataggaat cataataaga agaatagtag
     3961 caataccaat caatgtaggg attagattta gtaaaacagc ttgtccccaa cgtcctttta
     4021 gactctcttt tgcttggcgt tttaattctg cagaagattg catgattttt ccctcctttt
     4081 ctttaataac accaatatac catgtatcaa aaaatatttc tgtcataatg tttttctttt
     4141 ttttgttatt cataaaaaaa ggataaaaaa aagaatatta aataaagtag aaggaagccg
     4201 agggaacttg caaaaagcac ttgaaacgat tatgatggtg ggagttgtca agatatttta
     4261 tatagaaagt agggaaatga atgacgcaac ctgccattcg ctatcgttta atcaagaaag
     4321 aaaaacatac tggcgcgcgt ttaggggaat tgatcacgcc acacggaact ttccccacac
     4381 caatgttcat gccagtagga acattagcta cagtaaaaac aatgtcccca gaagagttga
     4441 aagaaatggg tgctggcgtt attttaagta atacatatca tttatggcta cgccctggtg
     4501 aagacttagt agaagaagct ggcggactgc ataaatttat gaactgggat caaccgattt
     4561 taacagattc aggcggcttt caagtttttt cattaagtga tatgcggaat atcgaagaag
     4621 aaggcgtgca tttcaaaaat cacttgaacg gttcgcgtat gtttttatca ccagaaaaag
     4681 caatcaacat ccaaaataaa ttgggctctg atatcatgat gagttttgac gaatgtccac
     4741 cattcgatga aagttacgac tacgtgaaaa aatcagtaga acgtacgtct cgatgggcag
     4801 aacgaggatt gaaagctcat gctaatccag accgtcaagg attatttgga atcatccaag
     4861 gagcagggtt tgaagatctt cgtcgtcaaa gcgcgaaaga tctagtcggg atggatttcc
     4921 ctggttactc aatcggcggg ttatctgtcg gggaacctaa atcagaaatg aatcgtgtat
     4981 tagaattcac tacaccgttg atccccgaaa acaaaccacg ttacttgatg ggtgtcggtg
     5041 ctgctgattc attgatcgat ggtgttatcc gtggagtaga catgtttgac tgtgtcttgc
     5101 ctactcgaat cgctcgaaat ggcacatgta tgacttctca aggccgtcta gtagtgaaaa
     5161 atgcgaaata tgcccatgat ttccgtccaa ttgatgagaa atgtgattgt tatacatgta
     5221 aaaactatac acgtgcctat atccgccatt tgatcaaatg tgatgaaaca tttgggattc
     5281 gtttgacttc ttaccacaat ttatacttct tgttgaatct aatgaaacaa gtacgtcaag
     5341 caatcatgga tgataatttg cttgaattta gagaagcctt ttttgaagaa tacgggttca
     5401 ataaagaaaa cgcaaaaagc ttctaaagga aaatctttta aaaattaagt aaaaaactag
     5461 tgttatcagc atttttctgc taaagtgttt tttgtagata cagaattagt gaggtgaaaa
     5521 aaatgggaac attaccaatg cttgtgatgt ttatcgcgct attagcaatg tggtttttta
     5581 tgtcacgttc gcaaaagaaa caacagcaag aacgtcaaaa cttgttagat agcatgaaac
     5641 caggtgattc agtcgtaacg atcggcggat tacatggagt tgtttcagaa atcgacaatg
     5701 acaaacggac agttgtttta gactgcgaag ggatcttcct tgagtacgat cgtgcagcaa
     5761 tcaaaacggt caaaccaggg actgtcgtaa caaatgatgc aacgactact gttgaaacaa
     5821 cagaagaacc agctgagaca gttgaagtaa aaactgaaac aacagaaacg ctggaagaga
     5881 cagaagagaa ggaagaaaaa taagtatcaa agcttattta aagacgaggt agggcagaaa
     5941 gatgtcctac ctcatttttt attcaaaaaa gaaagagata agagcatggg atatattgct
     6001 caatattgaa taatcgggtg tgtcatataa ataataataa ataactttat atatttttct
     6061 atacaaacac ctgtaaataa agcaatttta tatttaaaaa taactgtgaa aaaaatcaca
     6121 aaaaagtgtt tacatagaaa aataaatatt gtatgatata catgtgaatt atttaacaaa
     6181 taaccatgac ccattaggag gataatgatg gctaaagtaa tagaaaaaga aaaaacgaag
     6241 acaattgacg tacaagcaat gattgatgat ttggcagaaa aagcaaatgc agcattgaaa
     6301 gaaatggaaa gctttgatca agaaaaagta gaccatatcg tgcatgaaat ggcaatggca
     6361 gctttggatc aacatatgcc attagcgaag atggctgtag aggaaacagg ccgcggtgtt
     6421 tacgaagata aagcaatcaa aaatatgtat gcgtccgaat atatttggca taatatcaaa
     6481 catgataaaa cagttggtgt gatcaatgaa gatgtccaaa aagggttgat tgaaattgct
     6541 gaaccagtcg gtgtggtttg cggagtaact ccaacaacga atccgacttc cacaacgatt
     6601 ttcaaatcaa tgatcgcgtt gaaaacaaga aatccaatcg tttttgcttt ccatccaagt
     6661 gcccaaaaat cttctgcaga agcagcacga gtggtacgtg atgctgctat cgctgccgga
     6721 gctcctgaaa attgtatcca atggatcgaa catccttcga tcgaagcgac ttctatgcta
     6781 atgaaccatc caggtatcgc gatcgtctta gcgacaggtg gagctggaat ggtcaagtct
     6841 gcttactcta caggaaaacc agctttaggt gtaggtccag gtaacgtacc agcttatatt
     6901 gaaaaaacag caaaaattaa acgtgcagtg aacgatttga tcgtttcgaa aacatttgat
     6961 aatggaatga tttgtgcttc tgaacaagct gtgatcgtgg ataaagaaat ctatgcagca
     7021 gtaaaagcag aattccaagc acaccaagtt tatatcgtaa aaccagatga attgcaaaaa
     7081 ttagaagatg cagtgatgaa cgaaggaaaa tatgcggtca atccatcaat cgttggacat
     7141 tctgcgatgg aaatcgcaaa attggcagga atcagtgtac caaaaggaac gaaaatgctg
     7201 attgctgaat tggaaggcgt aggcccagat tatccgctat caagagaaaa actttctcca
     7261 gttcttgcca tgatcaaagc taacaacacg gaccatgcgt ttgatttgtg tgaaggtatg
     7321 ttgaatcttg gaggattagg acatacagca gttatccatt cagaaaacga agagttgcat
     7381 gtcaaattcg gtcttcgaat gaaagcttgt cgtattttag tgaatacacc atctgcagaa
     7441 ggcggcatcg gtgatatcta taacgaaatg attccgtcat tgactttggg atgcggttct
     7501 tatggtaaga actctgtttc tcgtaacgtc tctgctgtaa acttaatcaa tgtcaaaact
     7561 gtagcgaaac ggagaaataa catgcaatgg ttcaaattac cgccaaaaat cttctttgaa
     7621 aagaactctc tattgtactt agagaaaatg gaaaacgttg aacgtgtcat gatcgtttgt
     7681 gaccctggta tggtccaatt cggttactgc gatacagttc gtgaagtatt ggcacgacgt
     7741 aaaaatgatg tgaagatcga agtcttctca gatgttgaac cgaacccatc gacaaatacc
     7801 gtatacgcag gaacgaaact gatggcagac ttcaagccag atacagtaat cgctcttgga
     7861 ggcggttctg caatggacgc agctaaggga atgtggatgt tctatgaaca cccagacaca
     7921 tctttctttg gtgcaaaaca aaaattcttg gatatccgta aacggacata taagatcgac
     7981 aaaccagaaa aaacacaatt cgtatgtatc ccgacaacat cagggactgg ttctgaagta
     8041 acgccatttg cggtcatcac tgacagtgaa acacatgtga aatatccgtt agcagattat
     8101 gcattgacgc cagatgtcgc aatcgtcgat cctcaattcg tcatgtcagt tccagcatct
     8161 gtcacagcag ataccgggat ggatgtgtta acacatgcaa tcgaatccta tgtttcagtc
     8221 atggcttcag attatacacg tggattgagc ctacaagcaa tcaagttagt ctttgactat
     8281 ttagaaaaat cagtaaaaac acctgatatg gaatcacgtg aaaaaatgca caacgcttct
     8341 acaatggctg gtatggcgtt tgctaacgca ttcctaggta tttgtcactc agtcgcacat
     8401 aaaatcggcg gggaatacgg gatccctcat ggacggacaa atgcgattct tttaccgcat
     8461 attatccgct ataatgcaaa agatccacaa aaacatgcga tgttccctaa atatgactat
     8521 ttccgtgcag atacagatta cgcagatatc gcaaaattct taggtctgaa aggcgaaaca
     8581 acagaggaat tagtcgaagc tttagcaacg gctgtttatg aattaggaaa atctgtcggc
     8641 atcaacatga gtctaaaagc tcaaggagtc acacaagaaa cactagatac aaccgtagac
     8701 cgtatggctg aattagctta cgaagaccaa tgtacgacag ctaatccgaa agaaccattg
     8761 atctctgaat tgaaacagat catcattgat gcttacaacg gataagcaaa agaaagcgta
     8821 gaaaaaagat aagaaaatag atgaaaaaga acttggaaaa cgttgtttct ccaagttctt
     8881 tttttaattt ccaagtaact gaaagttact tttgttattt aacatttagg tcaattttag
     8941 acagtttttg ttcaaaaagc gatatttata gtggacggta ttactgctat attaaggata
     9001 taaaatgaaa gcgtttaaaa aggtggcgta aagatgatta ttaaagaaga gatttttgta
     9061 cctaaagaat tagtgaaaga aaaaattgac ctgctcgttg aaaacctgac aacgatcaaa
     9121 gacgataatg gtgaattttt gttggacttt gatggactga aagtagatga caaaagctgg
     9181 acagtgtgga attggccaca aggtgtcggt ctatatggta tttataaaaa ttaccagatg
     9241 acaaaaaatc ctcgcgctta tcaagtggtc aatgaatggt ttgaggatcg tatggaagaa
     9301 ggcgctccgc ccaaaaacgt caatacaatg gcaccgctat tgactatggc ttacttgtat
     9361 gaagacacga aagattcacg ctatttgcct tatttagaac aatgggcaga atgggtcatg
     9421 aatgacatgc ctcggacaaa tgaagacggg ttacagcatg ccacatatgg accggaaaat
     9481 aagaatcagt tgtgggacga tacattgatg atgacagtgc ttcctttggc aaaaatcggg
     9541 aaactgttga atcgcccaga atatttagaa gaagctcgtt accagtttat gatccatatc
     9601 aaatacttga tggataaacg aacaggattg tggtatcacg gctggacgtt tgaaggaaat
     9661 cataactatg ccgaagcatt ttgggctcgt ggaaactgct ggttgacgat tgctattcca
     9721 gagatcattg aaatcttaga attatcgaaa gaagatgcat tgcgcaaatt attgatcgaa
     9781 acacttgaag cacaagtgcg tgcattaaaa acttatcagt ctgaaagcgg tttatggcat
     9841 acgttgttgg atgatccttc ttcttacgta gaatcttctg caactgcagg atttgcttac
     9901 ggtattttga aagcggtcca taaacgttat ttaccacaag aatataaaga agtcgcttat
     9961 cgtgctatcc aaggattgct tgaacaaatc gatgaaaaag gagaagttca aaacgtttca
    10021 atcgggacag gaatggggga cagtttagat ttttatcgga atatcggaat cacagcaatg
    10081 ccttatggac agtcgttaac ggtgctttgt ttgacagaat tgctcgtctc ttattgttaa
    10141 aagaaaggaa acccatatga aaaaaacatc actgctgttt gcagcaagtt cgcttagcct
    10201 aggtctgcta ggtctaagcg gctgcggaaa taattctagt gtggcaactg tcgcagatgc
    10261 agatgtaaat gagatagtta ccttgcgctt tgcttatgca agcaacagcc agccagtaat
    10321 tgatgcaatg aatgaatttg ggcgtttagt aaaagaaaaa acagatggtt ccgtacagat
    10381 ccagtatttc ccagatggac aactgggtgg agaacgtgaa ctgatcgaat tgacacagtc
    10441 aggagcagta gatttcacaa aagtaagtgc ctcagcgttg gaaagtttct ctaaagatta
    10501 ttcgattttt tcagttcctt atctattcaa tgatgaagaa catttcttta aggtgatgga
    10561 taatgaagaa ataatggagc caatctacca atcgaccaaa aatttaggat ttaccggatt
    10621 gacctattat gattctggtc agcgcagctt ttatatggta gacggtccga tccatacgcc
    10681 ggaagatttg gagggaaaga agatccgtgt gatgcaaagc gaaaccgcta tcaaaatggt
    10741 agagctttta ggcggttcgc ccgtacctat gggaagtgat gaagtgtaca cgtctcttca
    10801 atccaatttg atcaacggat cagaaaacaa tgaatttgtc ttgtatacag ctggacatgg
    10861 tggtgtggct aaatactatt cctatgatga gcatacacgt gtgccagata tcatcatcat
    10921 gaatgatgcc atcaaagaac agctaactga tgagcaggaa aaagccattg aagaagcagc
    10981 gaaagaatca acggtttttg aaattgaagc ttttgcaaaa gcaattgaag aagaaaaagc
    11041 tttagcacaa gaagaacatg gagtccaatt caatgatgta gataatacac cgtttcgaga
    11101 ggcagttgcc ccacttcatg atatattcaa aaacgatcct acctacaaag acctttatca
    11161 aaagatccaa gagcaaggag cgtagctgtg atgaaaatga ttttaaacaa ggtattagag
    11221 atcctgggag ctgttttgct tgttgggatg gtcgctgttg ttttatggca agtattttcc
    11281 agaacggttt taggaaatcc aaatacggtc acggaagagc ttgttcgatt cggtcttgtc
    11341 tggtttgcca tgttgtcttc cgcgtatgtt gtgggacaaa aagcacattt agccgtaacg
    11401 gttttaagtg aaaaattaac tggcaaaaaa agtaaaattt tagaagttgt tgttcaaagt
    11461 ttatttctgg tatttgctgc gatgatcatg gtgtatggcg gatggaatgc tgtcacattg
    11521 acaatggggc agatctcgcc ttctttaagt attcctatgg gatatgttta tctgtcagta
    11581 cctgtatcgg gggtactcat cattatctat agcctgatca atctaatcga tacattaagc
    11641 aacaagccag caattcaaga aaaaatataa aaatggagga ataaaatggc aatagaagcc
    11701 ggattagtgt tattttttgt atttgttgtg ttgcttgtat tagggatgcc gattgctata
    11761 agtattgcat tctcatcgat gatgacttta ttgttagtta taccgtttga tgtttctgct
    11821 tttagttcag ctcaaaaaat ggtgggaagt atcaatagtt tttcgctgat cgctattccg
    11881 tttttcgttc tctcgggcat tatcatgaat aatggaggga tagctaagaa actagtggat
    11941 tttgcgatgt tgttcgtcgg gcgcgtgccg ggggctttgg ctcatacgaa tgtgttaggg
    12001 aatgctttat ttggttccat ctctagctcg gccattgccg cttctaccgc gattggcgga
    12061 gtgttgatcc ctcagcaagt ggaagaagga tatgaccgga agtttgcgac agcggtcaat
    12121 atcgcgtcag ctccgacagg tatggtcatt cctccaagta ctgcttttat catgtattca
    12181 cttgttgctg gtggtgcttc gatctctgct ttgtttatgg gaggttatct cgtaggcgct
    12241 ttgtgggcgc taggaatcat gctagtagca ttcatcgttg ctaaaaagaa taaataccct
    12301 gttgtcgaaa aaggacagat ggctcatgct ggaaaaataa taaaagaggc gattcctagc
    12361 cttctattga ttgtcatcat tatcggtggt atcttgacgg ggatatttac agcagtagaa
    12421 gcttcagcga tagctgtcat ttactccctg ttgattgcta tgttttacta taaaacggta
    12481 aaactaaaag atatacctaa tatgttgttt caatcagtag caatgtcagg gacgatcatg
    12541 ttcttattgg ctacttcttc catgatgtct ttcgccatgg cgtttaccgg tattcctcag
    12601 gcaattagtt cgttgattat gggcgtaacg gataataaat ttattattct gttattagtc
    12661 aatcttgtgt tattactggt gggtatgttt atggatgtgg cgcctgctat cttgattttt
    12721 acaccaatat ttttaccaat cgtcacaagt gtaggggttg atcctgtaca ttacgggttg
    12781 ttttcaatca tgaatctgtg tgtaggctcc atcacgccgc cagtaggtac aggactatat
    12841 gtcggtgcaa gtgtaggagg cgtaaaagca gaggcaatgc tgaaaccgct tcttcctttt
    12901 tatggggtta tcttagtcgt cttgtttttg attacttact tcccgcaaat cgtcatgtgg
    12961 ctacccaata tgctgagtta ggagaatagt tatgttgaac attacaatta gaggacatga
    13021 tctttccgaa gtccaaacga tagaagatct tgcagaaaaa acaaaagaac aagggattca
    13081 tacactgcag ctcgccttag gtctttcgtt tcctgaaaca ccttctggcg caaatgagat
    13141 caattctggg atgggaaatt atgtcaaacg agttttagaa aagcaagaag tgaccgtagg
    13201 aattttaagt tgctatatca atatgattca tccagattta acgatacgac aagagttgct
    13261 gacaaagttc gagcagtatc ttcgctatgc ttcttccttt ggtgcgtcga tggttgcttc
    13321 ggaaactgga tgtgttttgc cggaaatcca atatacggaa gaaaatttca cagatgaagc
    13381 atttgctgaa gctgtgtccg ttatccgtcg cttggtaaaa gctggagaaa aataccaaat
    13441 gatggtgggg atagaaccag gtttgaatca tccggtgtat tctttagcaa gggtagagca
    13501 gctgatccaa gcagtagatt cggactatct aggaatcatt ttagatccga ccaatttgat
    13561 cacaagtagt gattatcaag aacaagtcca attggtagaa gaagcttttg aacgttttgg
    13621 tgaaaagata tgtgcggttc atttgaaaga ttttcgtgtc gaacaggaaa aaatcgtgcc
    13681 ggtaaatttg ggagacggtg tgatcgagta cacaaaaatc aaagaaatca tcatgaagaa
    13741 tcgtccgtac ctgtatgtgg ttcttgaaga aacaaaagat gatgggattc gttatggaag
    13801 aagtcttctt gaataatgta aagaagacgt tggttaacta atatttagaa tggagggggc
    13861 ggggctagaa gatgccacgt ctcttctttt ttataagagt atataaaagc agctcttttt
    13921 gattacaaaa aacgtggtat aataaaattg tgcataagtg aacaaaagga ggtgcggcac
    13981 atgctccaaa agaaaatcag cggtgaacaa gtcaatacga tggtttctga tcagtatgaa
    14041 atctatcatg tcaaagatgt cgtcagccaa aataaaacga tctatcatca tcatgatttc
    14101 tatgagatcc atgctacatt aaagggagaa gcgacttttt atttgaacgg acgacaattt
    14161 acgatcaaag caggaagtgt gctgctcatc cattccaatg atttgcatcg tatcgtccgc
    14221 caatcttcag atgtattcga gcgtgtctat atctttgtca ccccttcttt tctagaaagt
    14281 cgttccacgc catggtctaa tctatcggct tgttttcaac caatgggaga gaagaggagt
    14341 cgtgtattgc aaatagaaca ggaagtattg aagcaaaaat tatcatttat cgaccatcct
    14401 cctgataaaa aaatttacgg tgaagacata aaatatgaac aagctctggt agaatacttg
    14461 atttttctca atcaagttgt acaaaaagaa gagagtgcgc aagaacagaa tgctgtagtt
    14521 cctaatgagc gtgtggaaca aatgttacaa tatatctcaa aaaatttatc tcatccgctt
    14581 tctttagagg aaatggaaaa gcagtttttt gtcagcaaat accatatcac acgagaattt
    14641 aaaaagtaca ctggatttac gtttcatcag tatgtaatga agaaaaagct gatctatgcc
    14701 aagcacttgt tgcgagaata ccgcagctct agtgctgtat atagtaaaag tggtttttct
    14761 tcttatccgc attttctgaa agcattcaag agagagttcg gcataacgcc taaagaattt
    14821 ttgaaacgtg atacacagaa acagttggtt cattatgaac attttgaaga tgaacaatga
    14881 gaatgatcac taaaaaataa ccgcagtagc tgctgttgtt tacatagaag cagaaactgc
    14941 ggttatttta tttttatcta tatatttcaa aatattttga aaaaatgacg tacatattat
    15001 atgaatcagc tgaatttacg aaagtctctc ggcgatagtc ctgtttttgc tttgaacagg
    15061 cggctaaagt aagcaaaatt ctcaatccct atttcttcgg aaatcattcg aaccgtaaat
    15121 tctgtatacc gaagaaggtc tttagcgtaa gaaagttttt tgctgatcaa ataatcgatt
    15181 ggtggagaac cgataaattt ggaaaaatct ttgctcagct gatatttatt caataagaat
    15241 tgttgttcta attgatcaag tgtaatcgtt tctttgaaat gttcgtctaa gtattgcttc
    15301 agtttgtaaa cgtaggcggg aatatcctct tcttcgaaat ctagctgata cttttgcaaa
    15361 atcagttcat tcagcaactc gtggatagct acagaggact ggaaatcggt acgggcattc
    15421 gtgccttgtt gcatgtggat caattctgtg atcaaatggt ggatcttgtt ttctgatgga
    15481 tcccctgttg aatggaaggt gttatggccg tcttttgtga actcctgata aaatgattgg
    15541 acgttctgac cattcaaatg gatccaatcc atttcccatg gttcttcgct gatcgtttga
    15601 taacgctgat attcttggca gtcaataaaa aataagtctc cagcttttag ctgttgctga
    15661 ttatcattat atgtaagcga acctttgcca gacaaagtaa actttatcaa gtaagaaggt
    15721 aaatgtgctc gttcagtata gtaagggatt ggtgctttga agtaaccgat ttcttggata
    15781 taaaaaaata aattcctgct tctttgtgta ggcgtcaaga tcactctttt tgagtcttcc
    15841 gaccatgagt ggttggcttt ttcccagtaa tccatgtaaa cactcccaac ttgtcaagat
    15901 aatgcaatta tataccaaaa tagtgtgaag caaaatataa gattctgtat tatgatagca
    15961 ttgttaataa atgataacgc tttattaata aagtgctaat caacaataaa gtaaaagagg
    16021 tggagaaatg aatccaacat ttgttgccat cgatatcggt gcatcaagcg gacgactaat
    16081 gaaaagtacg agggatgcaa aaggttcttt gatcttggaa gaagtacacc ggttcaaaaa
    16141 cggctttcgg aacaaagacg gtcacgatcg ctggaagatc gattatctta tcaaagagat
    16201 tttgattgga tttgaaaaat taaagcagac agggattgat cgcctttttg cggggatcga
    16261 tacatgggca gtcgattact gtctgattga tgaacaaggg gatcggataa atgatccgat
    16321 tgcttatcgg gacaagcgta ccaatggagc agtagaacag ttttctgaaa tctattctct
    16381 agataagttg tatgagcaga cagggattca gatccagcct ttcaatacct tgttccaatt
    16441 gtttgctgaa gaaaaagaaa atttggcaaa agcacataaa ttgttactga tacctgatta
    16501 tttagggtat gtctttactg gtaacatggt gacggagaaa actaatgcat ctactatgca
    16561 gctgctgaat gcagggacaa aagaatggga aatagaactt cttgaaaaaa tcggtgtctc
    16621 gaaggaatta tttccaccat tgacagagcc gggaacgata ctaggagatc tgcaaaaaga
    16681 acaattttca aaatatgatt tgccagatgt gacctttatc acagtagcaa gtcatgatac
    16741 ggcgtcagct gtattaggaa cgccaggtca aggagaacgt tggggttata tcagcagtgg
    16801 gacatggtcg cttttaggga ttgaaacaaa gatcgccaat gtttctcgca atgctttttc
    16861 tgaaaattat acgaatgaat ggggtgccca taacacggtg cgttttttga aaaacatcat
    16921 ggggatgtgg ttgatccagg aagttgcccg aatgcaagag tacgagtaca gttatgcgga
    16981 attggcagag cttgctgcaa aagaaaaacc gctgcagcaa gtgatggaaa tcaatgaccc
    17041 tcgatttttg aatcccccaa atatgataga agagattcag caatactgtt ttgaaacaga
    17101 gcagccagtc cctgtctcat cgggagctat cgctcgttgt gtgtatgata atcttgctct
    17161 ttgttacgca caagagctga tcaaagtaga acacttaact ggaacgaaat tggaaaagct
    17221 gcacatcgta gggggcggat cgaataatcg tctactgaat caattgacag cagattatgc
    17281 cggaatcatt gtagaagcag gacctagtga agccacagca atcgggaatg ttgccatgca
    17341 aatgctcagt acaggtcagt tttcgaatat agaacaagca agaaatgtaa tcaaacagtc
    17401 gtttccatgt gaaacttttt acccagatga aaataagcaa aacacgatgg aatggtacgt
    17461 gaataaaatc aaaggagtaa tcgtatgaac acgattgaaa gaaattacga acaagcaaaa
    17521 gaaaaatatg caactatcgg tgtagataca gatgctgtac tagaaaagat acaggacatc
    17581 aaaatttcta tgcattgctg gcaaggagat gatgtcaaag gtttcttgac accggatggc
    17641 gaattgaccg gtggaatcat ggcgacaggg aattttccag gagccgcacg aacacctgaa
    17701 gagcttagac aagatctgga gaaggcttat tcgttgatac cgggcaaaca caaattgaac
    17761 cttcatgcta tctatttgga tacagaagaa tctgtcgatc taaatgaaat tgagccgaaa
    17821 cattttgaaa aatgggtaga gtgggcaaaa aaagaagaaa tcggtcttga cttcaatccg
    17881 actttctttt cgcatccaat gatgaaagac ggctttacat tggctcatcc agataaagaa
    17941 gttcgtgaat actggatcga acacgggaaa agaagccgca aaatcgcgga gtactttggg
    18001 aaagaaactg ggcaaacaag tatcaataac ttttgggtac ctgatgggat gaaagataat
    18061 ccgattgatc gttttacccc acgggaacgt ttaatggaat cactcgatga aatttttaca
    18121 gaagagttag atgaacggta tgtacaagat gcagtagaaa gcaaactatt tggtttaggc
    18181 gctgaagctt atacagtcgg ttcccatgaa ttttatatgg gttacgggtt gactcgtgac
    18241 aaacttgttt gtctagatgc tggacatttt catccaacag aagtgatttc caataaatta
    18301 tcttcattag ctttattcag caaaggaatc atgttgcatg tttcccgtcc agtgcgttgg
    18361 gattcagacc atgtggtttt gatggatgat gaattgcagg aaatcgctaa agaattagtc
    18421 cgtaacgaat tgttggaaaa aacaaatatc ggtctggatt tctttgatgc aacgatcaac
    18481 cgtatcgctg cttgggtcat cggtacgaga aatacacaaa aagcactgct gaaagctatg
    18541 ctggaaccag ttgagcgatt gaaagaaatg gagctggctt ttgactttac ttcaagaatg
    18601 gcttatacgg aagaattgaa agatttcccg tatgccgatg tatggaatta tttctgttac
    18661 aaaaatcaag ttccagttgg tttggattgg ctggaagaag tccaggaata tcaaaaagac
    18721 gtgttggaat taagaaaata ggagtgtggc tatattgaaa aaaatagata ttttacaagc
    18781 gccttatgtg aaagaaatga tcgaaacgac gtcgaatctt tatcgcttgg gatgggatga
    18841 aagaaatggc gggaatattt cttatttact aaaagaagaa gagatcacac cgttcttgga
    18901 tcctgaaaaa gtgatccgcc gcatctcgat gatttttgat gccagccgtt tagcaggatg
    18961 ctattttatt gtaactggtt caggaagata ttttaaaaat gtagcgagcg aacctgccga
    19021 gaatcttgga atcgttcgag ttgctgaaga tggcaaaaca ctggaacttt tgtgggggct
    19081 ggaaaacgaa tgccttccta caagcgagtt gccaagtcat ttcatgagtc atatcgcccg
    19141 tttagaagta gacccagata atcggatcgt tatgcattgc catgctagtc atctattagc
    19201 gatgagtttt acgcatgaat tagacgaacg ttcctttagt cgtacgctat ggcaaatgtg
    19261 tacggaatgc ttagttgttt ttccagaagg aatttccatc attccgtgga tggttccggg
    19321 aacaaatgag attggggaag caacagctga aaaaatgaaa gaaactcgat tggttttatg
    19381 gccacaacat ggaatctacg ggtcaggaaa agacatggat gaagtctttg gtttgatcga
    19441 gacagcagaa aaggcagcag aagtctatac gtacgtcaaa gcgcaaggac caatcttgca
    19501 aacaatcacg gacgaaaacc tgtggcattt agcagatgcg tttggtgtca ctccaaaagc
    19561 aggttatttg gaggaagttc atacgaaagc aggtgtctga catggtgaaa aaagcttttt
    19621 gcatgaaagt ttacccagaa aaacaagaag aatacaaaaa aagacatgat gaactttggc
    19681 cagaaatgcg tacagcactt cgtgaacacg gggtcatcga ctattcgatc tatcttgatc
    19741 cgagtacaag tttgttattt ggttacttag tgatcgaaga tgaaaagtta tgggaaaaaa
    19801 tggcaaatac atctatcaat caaaaatggt ggaagtacat ggaagatatc atggagacaa
    19861 atccagatgc ctctccagtc agttgggaat tgatgccagt ctttgaactg tagcaacaag
    19921 caactgggca accggttgct tggggttctt tcgtttttat tgtgaaaaaa aatacaaatt
    19981 aggaggaata gaaaatgagt aatcgaatga ttttaaatga aacatcgtat tttggaaaag
    20041 gagcgattga gtcgatcgtc cctgaatttc agcagcgagg attcggcaaa gcagctgtca
    20101 ttactgacaa aggattgatc gagcacggta tagcaacaaa agtaacagaa cttctagata
    20161 aagcagcaat cgcttatgct ttatacgacg ggatcgtacc taatccaacg atccaaaatg
    20221 taaaagatgg agtggctttt gttaaagagg cagaggcaga ctgtttgatc gcaatcggtg
    20281 gaggttcgcc aatcgatacg gcaaaagcca ttgggattat tttgacgaat ccagagtttt
    20341 cagacgtcat tagtttagaa ggtgttgctg atacgaaaaa tccatgttta cctatattag
    20401 ctataccaac gacttctgga acagcagcag aagtaacgat caactacgtc atcacagatg
    20461 aagtaaatca ccgaaaattt gtttgtgttg atcctcatga tatcccaatc gtcgcgttca
    20521 tcgacagcga tatgatgatg ggaatgccga aaaaattggc tgcatcaaca ggtatggatg
    20581 ctatgacgca tgctattgaa gggtttatca caaaaggcgc ttgggaaatg actgatatgc
    20641 tgcatttaaa agcaatcgaa atcatcggcc attctttgga agtttctgta gatggcgatc
    20701 aaaatgggcg agaaaaaatg gcattaggac agtatattgc gggaatgggc ttctcaaatg
    20761 tcggtttagg actggtacac gggatggctc acccgttaag tgcatggtac aacattcctc
    20821 atggcgtagc gtgtgcagca cttttgccaa ctgtcatgaa atataacaaa gaatatactg
    20881 gagaaaagta ccgtgagatc gctcttgttc tagggattaa aggagcagct gaaatgtctt
    20941 tagaagatgt aagagaagcg gcttgtggtg agatcgatcg gttgagcaaa gcggttggaa
    21001 tcccagaaac catttctgaa ttaggtgtaa aagaagcaga tattccagca attgcagaag
    21061 atgctttgcg agatgtatgc acaccaggaa atccaagaga aacgacagta gaagaaatca
    21121 ttgctttata tcaaagtttg atgtaaaaac gaagcggatc ttcaacatta aattgcctgt
    21181 aaagagaaat ggtagtttat atctggatat ctcttttaaa ttgatggtat ttccgctata
    21241 atttttctta taaagaaata ggagaatatt atatggaaaa taaaaagcct tatggaactg
    21301 tattgatcaa agcctctaaa atactagact atttagcgga aaaccaagat gtctctttgc
    21361 agacgatcgc aaagggtgtg ggaatgacct cttctacagt cttgaaaata ctagatactt
    21421 tgttgatgat cggctacgta aataaaaatt cagagaaaaa ctatcgttta ggtgcaaagc
    21481 ttattcgcta cgcgaataaa aacattgaac aaatcgattt ggtagagttg actttaccgt
    21541 ttttagaaca gctgcagcaa aagatcgatg agactatcca cttaggggta ttggacaaca
    21601 atgagatctt gtacgtgaac aaactagatc caaaacatca aacgatccgc atgtcttcaa
    21661 aaatcggaat cacccgacca ttatacaatt ctgcgatggg caaagccgta ttagcagaat
    21721 tcagtgaaga gcagtacact gattatcttg aaaagcatcc gttgatccct tacacagaat
    21781 atacgatcac caatgcatta cggttgaaaa aggaaatcca aacggtaaaa gaaacccaca
    21841 tcgcatttga cgatgaagaa atcgaacgtg atattttttg tataggagcc tcaatcgtga
    21901 aaaacgaaca aatcattggt gcatttagtg taagtatgcc gaaatatcgt ttaacagatg
    21961 agacaaaaga acaaataatc agtgccctca agcaaacaaa aagcgaaatc gagcaaagaa
    22021 ttcaaaaata atgaaaaaag cgtttgcaat ttttcttttc tgccgtataa tatgggtata
    22081 gatttccaag ttataaaata aaatttctaa ataggaaata ggtggagaag atgaaaaaaa
    22141 ttgatatttt atctcgattg aaaaacgccg gagtgattgc ggtggtacgc ggaaaaagca
    22201 aagaagaagc tttgaatgct tgccacgcaa tcatcaaagg tggtctaact ggtattgagt
    22261 tgacttttac agtccctcaa gcagatcaag taatcaaaga acttttgtca ttctacaaag
    22321 accaaccaga aatagtgatt ggcgcaggca cagtattaga cgctgtcaca gctcgcttgg
    22381 ctatcttagc tggcgcagag tatattgtta gcccttcctt tgatcaagaa acggcagaga
    22441 tgtgcaatct gtatcaaatt ccttacttac caggatgtat gactattacc gagatcaaaa
    22501 cagcgctgaa aagcggggta gatatcgtca aactatttcc tggaagcgct tatggaccaa
    22561 gtatcatttc tgccttcaag gcgccgatgc ctcaagtcaa tatcatgcca actggcggtg
    22621 tgagtctgga caatatgaaa gagtggttcg atgctggtgt cgtaacagtc ggagtaggtg
    22681 ggaacctttt agcacccgca gctacaggag attttgacaa agtaacggaa gtcgcgcaac
    22741 agtatgcagc aaaaatgaaa gaaatcaaga ggtagctgct tatgggaaaa gtagtgacac
    22801 tcggagaaat catgttgcga ttgtccacag agcagggaac ccgtatcgat tcaagtgaac
    22861 gattcgctgc ccattatggc ggaggggaag caaacgtagc aatttcttta gctaattacg
    22921 gacatgaagc gatttttgct acaaaagtac ctgataacgc attgggaaaa gcagtcaaaa
    22981 agcacttgca atgttatgga gtagatacga aacaggtatt atctggtgga tcaagactag
    23041 gtacttatta tatggaaact ggtagtggcg aacgcgccgc ctcagtgatc tatgatcgtg
    23101 ccggatcaag ttttgctgaa atggatcatt tggaatggtc gctagaggag ttattccaag
    23161 gaatagatat atttcatgtt tcaggaatca ccccagcttt gtctaaaaaa tggcaaaaaa
    23221 tgacgaaaca ggtgatagaa gctgcaaaaa aagctggctg cctgatcagc ttcgatatca
    23281 actatcgtgg aaaattatgg acacagcaag aagccagcga agtaatccat cagcttttac
    23341 ctttagtaga tatctgctca gctggaaaaa tggatgctct ttatttgtta ggtatcgaga
    23401 aagcgccaga agcagaagaa caacctctaa tttattatta tcaaaaaatg caggaaaagt
    23461 tcccgaatat tcaggtgttt tattcgacca agcgtaccgt tcattcagca agtgaaaatg
    23521 aattgaaggg gacattgtgg atgaaccatg aatatgtgga atcccaagtc catagaatca
    23581 ccccaatcgt ggatcgagta ggtggcggag atgcttttgc aggtggcgtg ctccatggga
    23641 ttttatccaa tatgtctccg caagaaatca ttgattttgc tacggcagct tctgccttga
    23701 agcatacgat ccatggggac tgcaaccaat ttagtcaaga agaagtcgca caatttttag
    23761 catgcggctc tggaaaaatc attcgataga aggagtagaa gaaaatgcaa gaaatggaaa
    23821 cacgttatac acacagtcca gaagatatcc gtcattattc aacggaacaa ttgagaaaag
    23881 aatttttagt agaaaaggta tttgaaccag ggaaaatcag tttgacttat acgcacaacg
    23941 atcgaatgat ctttggtgga gtgacaccta ctgaaaaaga attagaaatc acattagaca
    24001 aagaactagg tgttgattac ttcttagagc gtcgtgaact aggtgtgatc aatatcggtg
    24061 gaccaggatt catcgagatc gatgggcaaa aagaagaaat gaaaaaacaa gacggatact
    24121 atatcggaaa agaaacacga catgttgtat tttcttctca agatgctgaa aacccagcta
    24181 aattctatat tagttctgtt ccagctcatc ataaatatcc aaatgtaaaa atcagtatcg
    24241 accaagtaaa accaatggag actggtgaag gcctgacact gaatgaacgt aaaatctacc
    24301 aatacatcca tccaaatgta tgcgaaagct gtcaattaca aatgggttat acgattttag
    24361 aaccaggaag cgcttggaat acgatgcctt gtcatacaca tgaacgtcgt atggaagctt
    24421 atgtctactt tgattatgcc aatgaagata cacgtgtgtt ccacatgatg ggcaaaccag
    24481 atgaaacaaa acatttagtt gtagacaatg aacaagccat tatttcgcca agctggtcga
    24541 tccattcagg tgtaggtaca agcaattact cattcatctg ggcaatgtgc ggagaaaata
    24601 tcacctatac agacatggat atggtgcaaa tggatcaatt aaaataagca taagggagag
    24661 aaaatgatgg aatttagtat ggatatgttt cgtttagatg gaaaagtagc attagtcacc
    24721 ggtgctgtct atggtattgg atttgagatt gcacgctctt tagctacagc aggagcaaaa
    24781 atcgtattta ataacttgaa tcaagaatca gttgatgaag gtatagcgca ttataaagaa
    24841 gcaggcatcg atgcaaaagg ttatgtctgc gatgtgaccg atgaagaagc ggttcaagcg
    24901 atggttcaac agatcaaaga agatgtaggt tcagttgata ttctagtcaa caatgcaggg
    24961 atcatcaaac ggacaccgat gatcgaaatg gatgcggcag acttccgcca agtaatcgac
    25021 gtggatttaa atgccccatt catcgtttca aaagcagtta ttccggatat gatcgaaaaa
    25081 ggcggcggta aaatcatcaa tatctgctcc atgatgagtg aattaggacg cgaaacggtc
    25141 agtgcttatg ctgcggcaaa aggcggatta aaaatgctga cgaaaaacat cgcttctgaa
    25201 tacggtcaat acaatatcca atgtaatgga attggaccag gttatattgc tacaccgcaa
    25261 actgctccat tacgcgaaac acaagaaaac ggtgaacgtc atccattcga tcaatttatc
    25321 gttggacgta cgccagcagc acgctggggc gagccaatcg atttggctgg accatctgtc
    25381 ttcttggctt ctagcgcatc tgatttcgtt aacggccatg tcttgtatgt ggacggaggc
    25441 atacttgcct atatcggaaa acaaccttaa aagagcttta gtacactgtt tagtggagag
    25501 gttgtgaaat cagcggattg aacgaatacc gaaggacagc tgattaaaca tcatttattc
    25561 gaaaaaagag gctgggacag aagcatttaa ctccaagaaa taagaaggaa ttcacgaaaa
    25621 ttgcttttca aatttttgtg aatttcagct tatttccgaa ggagttgctt ttacttccgc
    25681 cgtttgtacg tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt
    25741 tctgtgcgtc ttccatactt cactaagtcg atccctcttg cttcgcacca atccttcact
    25801 ggtccggaaa agatcagaga ttgttggtgt agggccgcgg tattcgttgc gccgaccata
    25861 gtataaagca gacgaagctc ttcttgccat tgcttcatca gtataatagt ttcttctacg
    25921 ccgtgattca tcagatgcgt cagtacggtt cctgaagtac ccacggcatt tgcgccgaga
    25981 caaagggctt taaatatgtc ataggcattg cggatacctc cggaggctag gatttccata
    26041 gaagtgtctg cttcatttgc ttcaagcaat gaagagactg tcgattgccc ccagtcagct
    26101 aaataactca gttcccgctt ggagcgacgg gcgttttcga tctgggtgaa gcttgttccg
    26161 cttcgaccgc tgatatcaac tgtatgaact cctaaagcag ctagatcatt gagcgtttct
    26221 cttgtcatgc caaaaccgac ttcttttacg atgaggggga cgtcaatggc tgtttgagtt
    26281 tcttgaataa gtactttcca attggtaaaa tcacggtctc cctcaggcat aaccaactct
    26341 tgaggtgcat tcaaatgaat ctgtaaggca tctgcgtgaa acaatcggat agcttctttg
    26401 gctctttcga cagaagtccc tgcaccgatg ttggcaatga ttttcccgtg aggatattct
    26461 tgtcgcataa tcgtataagt atcggctaaa gaagggactt tcaaggcagc gctgactgaa
    26521 ccagtggcaa tcatcaaatc tgcttctctt gcgacgattg caagatcttg gttgattttt
    26581 tttgtttttt cgcttccgcc agtcatcgca ttgatataaa atgggctgct tagtgtaaac
    26641 ccaactgcct gtgtacttag atcgacatca gaaactgcta tttgcggcaa agggttatgg
    26701 atgatccgta cgaagtcaaa ttcgtttttt tgtttatcat gaaaggcttt agctagtgaa
    26761 acatgttcgt cttttcgatt catcggtttt cctttctttg atcgctatag acatgtaacg
    26821 gcagtggagt gatttctgct ttttcccatg cactcattaa aggaagaatg ccagatttct
    26881 ggtcaacaat tacgattccg caatcgcccc cacctgcacc agaagatttt gcggctcctt
    26941 catactgttc agctaaatta cacaatttgt tcaaagcagg cgtttcgatg acgaccccag
    27001 tgattgcaga taaatcatgc agtaattgtc ggttttttcg aatcatctgt tggatcaacg
    27061 ttacattatt ttctttaaac cctttgatca tttcgttgac acattctgta ctatttttta
    27121 agaaaagctg ataagccacc attttatctt ctctcgaacg gtgaacttga tcgaccaaat
    27181 cagaagtaga ggcagggcta cccgtccaac caatcaataa acgtaaatct tcaggagcaa
    27241 tcaatggctc aatggataga cctggccaat ccagggcaag taactcactg atagaatgct
    27301 gagtttcttg ttcttggagc caaggatggt cgaaggttga gaaagcgatc cagccaccat
    27361 aacagctagc agcgatgtcg ccgcaggaac cattatcttg aactgctaaa ttggctagtg
    27421 ctgcaatctt gaaaatctcc aactgagata aattcaacgc gtaaaaaaca ttcaaggctt
    27481 tgaccgttgc aacggtcacg gcaccgctag aacccaatcc atatttccgg ccatttgaac
    27541 tgtctaactc acttgttact ttcagatcat aaaaggataa aagaatgttt ttttcttgtg
    27601 catacttttc agtcaagcga atagcagcaa ggatataatg aaaaggattt tcccgaatat
    27661 ctaaaactaa ttctccgttg cgtcttgtcc aacgtacagg catcccacta tattgtgcag
    27721 attggatact tccgactttt cgtgcagatt ctacagtgac tgtcacgaat tgatcgactg
    27781 cagcgataac tgctggatgg cctgtttcaa caactgcata ttctccggca atatagagtt
    27841 tgcctggtgc agatacttca atcataaaaa tctcccttta ttcaataatc gcaattcctg
    27901 gaccagcatg tgcagtaatt acttgttctt tgctaaataa tttggtaaat gtttcttgta
    27961 cctcagataa atggctgttt tccactaaaa ctttgacatt agggccagca tccatcgtaa
    28021 agtagcatgg aatgccttgc tttctcaatt gtcgcaccgc atccatcgct tttaagctgt
    28081 caggagacca gtaagtgaat ggaggctggg cagctaaagt cgttccatgc atttttagtc
    28141 cgtttctttc catcgtttct ccgagaagtt ggaaatcttt tgttttgatt gcttgtttca
    28201 attgatatag atccccttca acggaatcta accagccttg ataaaaactg gatgtttcga
    28261 ctgtccgacg catcccattt ctgctggaca cttctttttt ctggtcgttg atcaaaacga
    28321 aaaccattgc taaatcgtct tcgaaagaat cggaagggac tggcttagcg taagaactta
    28381 agtcgtcatg gcctttttcc cattcgacga aaccaccgaa aatacttcgg caagctgaac
    28441 cagacccgcg tcgagcaaat cttgaaagag agagatcatc taatccaagc ttaagagcag
    28501 tattgcaagc gcctgctaaa gcagctagcc cgctggcaga ggaggctaat ccagctgcgg
    28561 taggaacgaa attctgactg attactgaag cttttagtga gaggccggct tctttacgaa
    28621 aaaggtcaag aaactgactg actttttttg ttgctttttc gtcttgcaag gtgccatcta
    28681 gataaaattc atctaccata tagctatcag aaaagatgac ttctgtctct gtataaaatg
    28741 catccaatgt taacgaaagg ctgttgttca ttggaaggat gagttcttca tttttcttac
    28801 cccaatattt gattagagca atgttggtat atgcgcgtgc tttgccttta aacataggta
    28861 tgtactccta atccttgtat ccaagtttca gcagcacccg catcttcaag tgcttgactg
    28921 atttcttggg cttttgtttt tgtttgtgct aatgcaatca tacagccacc gcgtccaccg
    28981 ccagttaatt tggcacccaa tgccccggta tcttttgctg tttggatcaa tagattaaga
    29041 aaatcattgc tgattgtcag cttttccaga agtgattgtg attcatccat tgtctgtgcc
    29101 aacgtttctg gtgaattttc aatgattgct tgttttgctt gcttcgtcaa gtatcctaat
    29161 ttttggatca tttgtccagt ttcatgaggc tgggtttcaa agaggtgagc gacatctttg
    29221 acggcttctc ttgtttgtcc tttgattcct gtatcagcga caatcaaaaa agcatcgatg
    29281 ttcaaagaaa agtagtcgaa aggatgccct tttgtaaaat aaatcggctg caagctgcta
    29341 gtagcggctg catcgattcc actaggatta ccgtgggcga ttttttccga aagctggaca
    29401 ttttctaata gtatttcacg agacaaagga aatgctaagt aatcataaaa agcacgagtg
    29461 actgctgtgg cgactgcagc gcttgatccc attccacgtt cagcaggaat cgtgctttca
    29521 atggtcagtt gcaagttttt ttggatgtca tgctgttttt ttaagtgaat gaataatttt
    29581 ttgatatttt ttaatgcatg aggagcttcg gctaaatttc ctgaatagta ggaagaaacc
    29641 agttgatcgt ccattgcatc cagctcttca aggaatgcgg tgacttttgt tgcatagaaa
    29701 ggaaaggcaa tcgctggttc tccataaaca accgcgtgct cgcccatcaa tatgatcttt
    29761 ccgcttgatt ctccttggcc atagtttgcc ataatctaac tccttctcac gtaaaagtga
    29821 tttttaagca aaaaataaag cgcccaaaac gagttgcgct gcttcacgaa tttttttgtc
    29881 cactaagggt ctcaaaaaac attcctcctt tattttacta aaaccatctc agaagtaaaa
    29941 ctaagaatac gttttctaaa gaaaaaacac ttttttctta agaatttttt gacttttttt
    30001 cttctttgac tagaaaaaaa tacaattgac actactagat attgggggta tatttaaaaa
    30061 ggttggagtt aaacacaata tttagtgatg aagtgagctg gaggtaaatg agcgtgatcg
    30121 ttttagcagg tacaattggt gccggaaaat caagtttaac agaaatgatg gctgaacact
    30181 ttgatagtca ggcattttat gaatcgattg atgataatga agtcttgccc ttattttatg
    30241 caaaccctga acagtatgct tttttgctgc aaatttattt tttgaataaa cgttttgcaa
    30301 gcatcaaaca agcaatgaaa gatgacaata atgtattgga ccgttcgatt tatgaagatt
    30361 cactgctttt ccatctaaat gcagatctag gaagagcaac agaaacagaa gttcgtgtgt
    30421 atgatgaact gctggaaaac atgatggaag aacttcccta tgctgcccat aaaaaacatc
    30481 cggatttatt agttcatatt cgtgtatctt ttgatacgat gttggagcgt atcgaaaaac
    30541 gtggtcgttc gtatgaacaa ttgtcctttg atccaagtct atacgattat tacaaagaat
    30601 tgaacagacg ttacgatcaa tggtatgaag aatacaaaga aagtccaaaa atccaaatcg
    30661 atggagaccg ctataatttt gtggaagatc ctcaagcaaa agaagaagtc ttgaaaatga
    30721 tcgaagaaaa attagcagag attcgccaaa ccaaagtagc catttgattt acagttgctc
    30781 aaataaaggg taaaccttta tttgagcgac ttttttcttt atactggaaa caaatgtcag
    30841 gaggatagag tatgcgggaa aaacactatt ttaatcaaga ccgtaatttt tggatcaatg
    30901 tacagcaaaa cgatgtgcta gctgttaaaa acttaaaaga agaatatggc attagtgacg
    30961 agatgctgac ttattctcta gataaaaatg aacgggcgcg cgtagagtac gattcttttg
    31021 atgaagcgtt actgcttgta tcaaatgttc cgcaccagca aaaagtcgat aatcattatg
    31081 aaactagtcc tatcgctttt attttaaaag aagacggttt gtttacattt accacgccga
    31141 ataccgagta cgtgattcga ctaattcgat cgcttttgga acgaatgcca gacatgagtg
    31201 tatacagttt attgtttcgt acattgtttt tgatttctga ttcctttttt cctttaatcg
    31261 aggaagtgaa tagtgaacgt cagcggctta atctgaaatt aagagaaaaa acaacgaaca
    31321 agaatctgct gcaactttca gatttagaga tcggtttggt ttacttagtt acaggaacaa
    31381 aacaaaatgt agtactttta gaacaaatca aggcattggc tatttatcgc aagttgtcag
    31441 aaaaggaaaa agaagagttg gacgatgcgc tgatcgaagc acgacaagca gttgaaatga
    31501 cgaacttagc ttcgcagatt ttagaccagc tctctggcac ttataataat ttgctgaata
    31561 acaacttgaa tgacacgatg aaatttttga cggtctggtc gctgatcttg accgttccaa
    31621 ctattgtgac aggattcttc ggaatgaatc tccagttacc ctttacccat tccgttttcg
    31681 gatggggaat cgccttgatc atcagtttgg tcttatctat ttggatgctt attgcactgt
    31741 ggcggcggat tcgttgatct agtctttgat ctgcaaacca agggcttggg cgatcacaag
    31801 tgcttgctct tggttgacga ttagtcccgc caaagaatct tgagataaag cgattgctgt
    31861 gaagaaatta gtcgtaaagt ctaatccctt cagagaagtt cgaaaccagt tcgaaccggt
    31921 caactgattg tcagacaaaa aaaggttttt ccaagtgacc tcataaaatt cgctgtcttc
    31981 taattgacaa tgatcgaagg agacagcttt caagtttgta ctactaaagg aagccatcga
    32041 agcaatacaa tcagtgaaag tacagtctcg aagataactt tcggcaaaat tcgtacctgt
    32101 taatttacat tgatgaaaca cgacttggtg gaaactgcca ccaatccact ccagattgga
    32161 aaaatcacat ttttcaaaaa tgacattact gcattcaaaa tgacgtaaaa ctgttttttg
    32221 catcgtaagt ttttggatat gactctctct taataccata tttttggcat cgagatagct
    32281 ttggtcaccc ccgttgatca gaagaccaga gaagatctcc tcatcttcta aataaaactc
    32341 tccctttgta agaagaggaa gagaaggtgg aataggttcg atttttttca tgtgggttca
    32401 cctcgttttt ctttagtata gcaaagaagc gggaatcact gctagaaagt ctgctaatct
    32461 aatcattttc agaaaaggaa gacaaactgt atgaaaaaca ttgacaaaaa gattagtttt
    32521 tgctatacta tgatggttga gaaataaaag cagaagcacc cgcttctcgc cttagttgat
    32581 aatgtcactg ggctagatag ttttcactgg ttctattagg tgaagtacgc gcgggttctg
    32641 taagagaact cgttttttta ttgccgttta ttcggtaagc ttttctttct ctcataatat
    32701 ttggaggtga atgaccatag caaaggatat gatggttaac gacggcattc gtgcacgaga
    32761 gttacgattg atcggttcag atggtgagca attaggagtt aagacaaaag cagaagcatt
    32821 gaatattgca gaacaagcaa acttggatct tgtgttagtt gcccctggtg cgaaaccacc
    32881 agttgcgcga atcatggact acggtaaata ccgtttcgaa caacaaaaga aagaccgcga
    32941 agcgcgtaaa aaacaaaaag tgatcaatgt aaaagaagtt cgcttaagtc ctacgatcga
    33001 cttgaatgac ttcaatacaa aacttcgtaa tgcacgtaag ttcttggaaa agggcgataa
    33061 agtgaaagct tctatccgtt tcaaaggccg tgccattacc cataaagaaa ttggtcaaaa
    33121 agtcttgaat cgcttagctg aagaaactgc ggatattgca acagtggaac aaaaagcgaa
    33181 aatggacgga cgcagcatgt tcttgacgct ggcaccgaaa aacgacagta agtaatttga
    33241 atgactaact ggctgttgga cagccgatag tcggataacg aaagattttg aggaggaaat
    33301 atagtcatgc caaaacaaaa aacacaccgc ggatcagcaa aacgtttcaa acgtactggt
    33361 aaaggcggat tgaaacgctt ccgcgcgttt acaagtcacc gtttccacgg caaaacaaaa
    33421 aaacaacgcc gtcaattgcg taaagcaagc atggtttcta gtggcgactt caaacgtatt
    33481 cgccaacaac tagcaaaaat gaaataagaa gtacaaataa cagaatctga agatttattt
    33541 ttattaggag gaattataca tggcacgtgt taaaggtgga acagtaactc gtaaacgtcg
    33601 taaaagagtg ctaaaattag caaaaggtta ctacggttca aaacacactt tatttaaaac
    33661 agcaaaagaa caagtaatga attcatacaa ctacgcatat cgcgatcgtc gtcaaaagaa
    33721 acgcgacttc cgtaaattgt ggattgctcg tatcaacgca gcagctcgta tgaatggctt
    33781 gagctactca aaattaatgc acggtttgaa agttgctgaa atcgacatca accgtaaaat
    33841 gttagctgac ttggctgtta acgatgcagc agcatttact gcattggctg accaagcaaa
    33901 agaagctttg gctaaataag ctaaacaatt ataaagagga aagaagataa cgaaaagtta
    33961 tgttctttcc tcttttttta tttacaatcc tccatcaaat gaaacaggac aataacgtat
    34021 aagtctaaaa tagcataatt aaggtttttt aattgaaaac tgaacattta tggtcaccct
    34081 ttaatgaaag cgctaactac ataagttaga atgagtttga ctgatatatt agtttgctta
    34141 tcagaaaaac aaaatggacg gaggaataac atgagtgata ttattattgg tattttgtta
    34201 gttatctcat tctttttcat ggtctggtac tgtgtaaaag gctacaactt gatggtcggc
    34261 tttgccatca tggctactgt atggatggga ttagcgctag tcggaaacac gttttcacca
    34321 aacccggcga tggaagggca aggagtaatt gatgtgttga cgcatatcta tacgacgggg
    34381 ccagctgagt acgccaaatc gatcttggta aatgtcttct ttggtgcctt tttcgggcgt
    34441 gttctagtag atagcggaat cgcagctacc ctgattcgaa aggtagttga acttggaggg
    34501 gacaagccaa gaatcacgat gagcttacta tgtattgtaa ccgctgttat attcatgtcg
    34561 atgacaggaa tcggaccagt gatttctatt gcagttattg tgttgccaat cttgatgtca
    34621 ttaggtattt cagtaccggt tgcactgttc tcatttatgg gctcgattat ggctggaatc
    34681 tttgctaata tcgtcaattt caaacaatat caaacgattt atgctggttt caatccagcg
    34741 gctgaaagct atacttataa tgactatttc caaattggta tgattgggat gattgtaagc
    34801 ttagttgtgg tactaacggt cgctaatata tcaatgaaca aaaagaaacg ctatgcaatg
    34861 gcagcaaacg taccagctga aggtggcgac gcaccaatga tctcatggtt agccgtatta
    34921 ttaccagttt taggggtcgt tcttttagat cttccaatca tcttaggttt tattctagca
    34981 ggtatctggg cattgctgtt tactggaaaa ttgcgcggag gttataaaga aatctgtcgt
    35041 cagtttgcga aattatttac agatggcgca gtagatgttg caccaatggt tggtttcttg
    35101 atgaccttag cgatgttcaa taattcagct gcgtatgctt ctccttattt ttcagctatt
    35161 tttggagatt ggataccgca atcaccatta gtcttggcaa tcgtatttgc tatattgaca
    35221 ccactaggat ttttccgcgg tccaatgaat ctagtcggtt caggctcagc tattttagct
    35281 gtcgtattag ctgttaatcc aacgatgtcg ccagcctttt tgttcccgtt atttgcaatc
    35341 acaacgattg ctcctcagca tttagatatt acacaatctt gggttgcttg gggattaggt
    35401 tatacaaaag taacttctcg agaatatatg aagaaatcca tcccaactgg ttggatcatc
    35461 ggagcgatct tatgcctgat cacgttctta ttgtacggga acgcctagta aacaaaacgt
    35521 cgataaaaac gattagatga atggaggaaa agaaaatgaa acgttttgtg cgaatgggaa
    35581 ttgatgttgg cggtacacat acgaaagcag tcgcaatcga taatgcgacg cacgaaatca
    35641 tcggaaaatc ttcagtgaaa acaacccacg atgatgtccg tggagtagcc gcaggtgtcg
    35701 ttcagtcttt tcaaaattgt ttgcgggaaa ataatatcag tccagaagat gttgtgtttg
    35761 ttgcacattc taccacacaa gcgactaatg cactgattga aggagacgta gcaaaagtcg
    35821 gcgtaatcgg gatggcaaaa ggtggattag aaggtttttt agcaaaacga caaactagat
    35881 tgaacgatat cgatttaggg aataagaaaa aaatagagat tgtcaatgca ttcttacctg
    35941 tcaaacactt aaatgtagac cgtgtttcag aaacgatttc ttctttagaa agagaaagag
    36001 cggaggtctt ggtttcttct atggcatttg gagtagataa tggggaacca gaacgagttg
    36061 tttatgaagc agcatcggta aaatcgatcc ctacaacgat ggcttctgac atcacaaaat
    36121 tatatggatt gacaagaaga actcggacag cagcaatcaa tgcatctatt ttaccaaaaa
    36181 tgctagatac ggcaacctct acagaagatt ccgtacgaga agcaggggtc aatgtttctt
    36241 tgatgattat gcgcggagac ggcggagtaa tggaaatcaa tgaaatgaaa aaacgacctg
    36301 ttttaaccat gctttccggt ccagcagcat cagtcatggg ctctttgatg tacttgagag
    36361 cgtctaatgg tgtttatttt gaagtaggcg gaacaacaac caatatcggg gtcattaaaa
    36421 atggacgtcc agcaatcgat tattcaattg taggtggcca cccaacatat atctcttcat
    36481 tagatgttcg ggttctaggt gtggcaggcg gttcgatggt acgggctaat cagtcaggaa
    36541 tcatcgatgt cggtccacgt tctgcacata ttgccggtct agattatgca gtatttacgg
    36601 agacagaaaa aatcaaaggt cctaaggttg aatttttctc tcctaaagaa ggagaccctg
    36661 ctgattacgt caaggtagtg atggaagacg gagaagaagt gactattaca aatacatgtg
    36721 cagccaatgt ccttggatta gtgcaagaag aacatttttc ttatggaaat gtcccatctg
    36781 cacgaaaagc catccaagca ttagctgatt attgtcatac gacggttgaa gacatcgcag
    36841 aacagatcat ggaaaaatcc tatgctaaga ttgaaccggt gattttagaa ttggcagaca
    36901 agtatcactt ggagaaagat cagatttctc ttgtaggtgt agggggcggc gctgcctcat
    36961 tgattactta ctttagtaat aaaatgggtg tgaaatattc gattcctgaa aacgccgaag
    37021 tgatttcttc tattggtgta gcacttgcaa tggtccgaga tgttgtagaa cgtatcatcc
    37081 cttcgccaag taaagaagat atacgatcgt tgaaaaatga agcgatgaat aaagcgattg
    37141 aatcaggcgc tacaccagaa tcgatcgaag tccacgtaga aatcgatcca cagacttcaa
    37201 aagtaacggc tatcgctact ggttctacgg aagtgaaagc aaccgatcta accaaggaga
    37261 tcacaacaga agaagcacta gagcttgctg cagaggatat gcgattaaat aaaaatgaag
    37321 tttgcttatt ggaaaataca cctttctttt atgtatgcgg cgaacagaat cgttcaaaaa
    37381 atgctggaag tcttcggatc atcgatcaaa aaggatttat caaggtccaa cgtggacatg
    37441 cttcatgtat gaaaacaact gcagccaatt atatgacagc tgtcgaacaa ctttgggaag
    37501 atatggcagt ttatcaaact gaattgattg cccgaccaga attttatctc tgcttaggag
    37561 caagagtctc tgattttaca gcgacggatc tggaacaact acagcttttg atggatctgg
    37621 aagtatctac tatggaaccg gaggaagaag tgatcgtcgt tgccggaaat atcaaacaaa
    37681 cataagttag aagagttact aaacgaatta caacagatcc ccgaagaaat ttggggattc
    37741 taccagtttc ggcgagattt attttggaaa aagattcctt tgtccaagca gaaaattctt
    37801 atacaacaat caatcgattg tggtatcgaa acggcatgta gcatcaaaaa aaagtaccct
    37861 tttgccgatg taggagaaat ttgtgaacaa atggctgttc caatcgtttc ctgtgaatca
    37921 gagcaaataa acgaacgaat cacttttgca acttatgcag aagatgaagg gattcgattg
    37981 atgacggagc cgttagaaaa attaaaatgt tcaggactag cttcgatctc taaagaaaca
    38041 gcgcaagctt tgattattgg acatgaacta tttcaccaca tcgaagcttc tgttaaggga
    38101 atttatacgc aaagcgaaaa aattgtgctg tggcggttgc ctttttatac acatcaatca
    38161 aacattcgtg cattgagcga gatagcagcg atgagttttt caaaagagat gaatcaaagc
    38221 gatttttcgc cttatgtatt agaggcagtc ttactttggc catataatga aattcgtagc
    38281 caagggatct tagaagaaat aaaaaaaata gaaaaaagat gtacggagta tgatttagat
    38341 tacaaataaa gagactgtga caaaagtcgt gtcacagtcc tttttttccg aataaacgat
    38401 gttctcctgt caactcctcg gtcacaagtc aaaatattca acaaacatga gaagctgttt
    38461 tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc ttggaaaacg
    38521 gtgttcaaaa gcttgcatct gcggtaataa gtccagccaa gttaaaaaca taagaagcta
    38581 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctctcaataa
    38641 acggtgtgca atcagctgac cctcggtatt agctcaaaaa aaacggcaaa atatgaggaa
    38701 ctattttgcc gtttctttct ctaatactca ggtcaaaacg ctgattccaa aacctcttat
    38761 ttgatgggtc tgtcctgaat atcttcaaaa taatcggggt aattatgaat cacgtattct
    38821 tgctcctcga taatcatatg taaatgcatc gtgcaaagaa atccgacttc atcaaagtta
    38881 tgatcaatca ttgattgaag cattgtctga tgttcatcta atactcgacc ccagtctaat
    38941 tctgaaatcg tcaaacgtaa ccatctgaaa cggttcaagt gcgtactata actttctagc
    39001 caatcccaaa tttctcgttt tccagcaatt tcataacaag ttcggtgaaa atcagtatcc
    39061 aaatcaaaaa aagctttttt attttgagcg attactgcct gatcggtttt tccaactttt
    39121 cccgcgtata acgggctaat gaagcagatc ggatatcgat ttttgaaaca taagtgccgg
    39181 actgtggaat ggtttttaca agctcttgat tgcgcagttg gatcagtgct tctcgaatcg
    39241 gtgtacgccc gatagctagt tgttcttcta acactttatc ggagatttta cttccaggtg
    39301 ctaactcgga ataaatgatt tgtttacgta tagattcata agcttgctgt tgcaaattat
    39361 tgataaccat ttaaccttcc tttctatgca gatataatct attataacat aaatcgctta
    39421 caaatcgtgt gggcataaaa acacagtctg caaaaaaagc cctgataggc atgcctatta
    39481 gagcctcgaa aagaaaaata ttgaatcaat ctggtcgtac ctcttgtatc ggtttgacac
    39541 gaccgccgat tcttttagca aaagcttcgg attctttttt gtctttgaaa atgagcagat
    39601 tgtctaagtt tttttcccga gtgcgacagc cagttttatc gatgtaaccg tgcattactt
    39661 taacgacata catggggatc acctgctttt ttcttttcat tatacgaact actcgacaca
    39721 atacaagaaa aatgcttaga cggtctttat taagaattta catcatccaa agaagcgtac
    39781 gcttggaata actgatctaa ctccggattg actttgctca gcttcactaa tcgttgcgaa
    39841 tcagaaagta aaaaacagtg tttactactg ccagtagttt ttaatttttt gtcttcagtt
    39901 cccacaattt cgtagctaaa atccaaccgt gtccccgtat acttttggat agttggatgg
    39961 atgctcactt tttctccgta atggatcatt tctttatagc tgcaatttac ttccagaacg
    40021 gggatgatga tcccagattc ttcgattttt ttatagggaa accctagatg taccaataag
    40081 gctacccgag cctcttcaaa ccagcggata taattgctgt gatgaataat ccccatttga
    40141 tctgtttcat aataaaaagg ttctcgcaca taacctgtaa atttctccat gactcatgcc
    40201 tcgttttcca ttgatttttt acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt
    40261 tgtgtcggca aaacaatata ttgttctttt gccagctggt ctccaatgaa actatgaaga
    40321 taaatagctg ctgcaatcgt ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc
    40381 atcccagcta aagtgtcacc catgccgccc gttgccatag cagcagaacc taaaggattg
    40441 gtgtagaagt gctggtgacc ataaattttt gtctcatgac ttttcaaaac gagcacagca
    40501 ccgatttcct gttgcttctt tttgttttct ttatcccgtt gttcttgtat cggtagagaa
    40561 ctcaaccgtt gccactccat ttgatgaggt gtaagtacag tttgttcggg atagggtagc
    40621 aaaagatgat tagcagcaag taaacttaaa gcagagccat caatcaccag ccattgttct
    40681 tttgattggt tttctagtac ttgtttgaaa cgttccaaac tcttagaaga agtacccaat
    40741 ccgggaccaa tcaagagtac atctgcttgc tttattacgg aaagaaactg gtcagtatcc
    40801 gtccaaacta caatcattgc ttctggcaga tgactgtgaa gagcactccg atttttttca
    40861 tcagttacta cagtcgtgag acccgctccg ctgtgtacgg cagctaaagc actcataatg
    40921 attgctccgc catattgttc attgccgcca atcaaaacga tacgtccaaa tgttccttta
    40981 tgtgaaattt ttggacgagg tgtgatgact cttttcacta gttgttcgtt tatcagcatc
    41041 taaaaacctc cttttactca ttatagcgta tatttttttt agagaaaaac agataagaaa
    41101 aggaattgtc agattttttg aactattttt ttctgtaatt tgtggtatca tgaacacgaa
    41161 gacttaaata agtggaggat taactttatg acaattgatt ggcaaaaaga agtagaagca
    41221 cgtaaagaag acttgcttga agacttgaaa aatcttttac gtgtcaacag cgagcgcgat
    41281 gactcaaaag taacaccaga tgcaccattt ggacctggac ctcgcgacgc attgaaacat
    41341 atgttagctt atggcgaacg tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg
    41401 catattgatc ttggcgaagg agacgaaacg ctagggatat ttggacacat ggatgtcgtt
    41461 cctgcaggag atggctggga cacagatcct tatgaaccag taatcaagga tggaaagatc
    41521 tttgcacgcg gatcaagcga tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag
    41581 atcattaaag aacttgactt gaaactatca aaaaaagttc gcttcgtagt cggcagcgat
    41641 gaagaaagcg gctggggcga tatggcttat tatttcgaac atgaagaaga accagatttt
    41701 ggtttctcac cagatgctga attcccaatc atcaatggtg aaaaaggaaa tgtttcttta
    41761 gctttacgct tcaaaggcga caatgcagga gattatgtct tgaaatcttt tgtttccgga
    41821 cttcgcgaaa atatggtgcc aggaacagca actgcagcac ttcaagtacc aagtgcagat
    41881 gcagctatcg cgatggaaga agcattttac caattcatcg aagcaaatcc agtaagcgga
    41941 acgattgaag cggacaatac gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt
    42001 gcaagcccac aatctggtat caatgcaggt tctttcttgg cattgttctt agataactat
    42061 gaattcctag gatctgctaa acaatttatc catgtagcag ctgcttatgt ccatgaagat
    42121 ttttatggag aaaaactagg agtcgcttat gaagatgaaa aaatgggcaa attgacaatg
    42181 aatgctggac tatttgcttt tgaagaaaat ggtacagagg aagcgaactt catcaatatg
    42241 aatttccgtt ttccaaaagg tgtaacagta gacggattgc aaagtgacat cgaacaaaca
    42301 gtggggcaag aaggcgcaac agttactcga ggtgctcgcg taatggaacc acattacgta
    42361 ccaatggatg atccattggt ggctacatta ttgcaagtct atgaagacca cactggagaa
    42421 aaaggctacg aacaaatcat cggtggcgga acttacggac gtttgttgaa acgtggcgtt
    42481 gcttatggag cgatgttccc aggatatact gatacaatgc atcaagcaaa cgaatttatg
    42541 agtcttgatg acttgttcag agcaacagca atctatgcag atgccatcta tcgtttggcg
    42601 aaataattaa ttaaaaagag gatcaagaat tgcaaattat ttttgcagtc ttgatccttt
    42661 ttttactttc tactgtggta ttcatgataa acatgatata gattcaattc atattctttc
    42721 ttagcgttcg tgacgactgt atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa
    42781 gtcatcaatc cagtacttaa aatcgcagaa gggatgcgtg taataaagct tgtcagcata
    42841 tattcgcgaa tcacaggaat ccccgtgacc aatccaaata aaaagaagaa gatggtccaa
    42901 atcccaaaga aaagcaaagg cttataatct ttaaacattt taataatcat catgatcact
    42961 ttgaatccgt cagagaatgt attcaatttt gattcgctgc cttcaggacg atcacgataa
    43021 tcgattggga tttcaacgaa cttgaatttt ttatctaaag catggatcgt caattccgtt
    43081 tcgatttgaa aaccagaact cataatagga aaacttttga caaagatacg attgaatcct
    43141 cgatagccgg tcatgacatc aagaattttt gttttataca ttctagtaat tgtatttcta
    43201 acaaggttat ttccaaaatc gtggaaaggt ctcttattct catcaaagta ggttccattt
    43261 gataggcgat caccaatgac catatctgct tcaccagaac gtaatttctc gagcaaacca
    43321 tgtacagctt ctgcaggata agtatcatcg ccatctacca ttaaataata gtcggcatcg
    43381 atatcaaaga acatttggcg gatcacattt ccttttcctt gacgaggttc tttttttacg
    43441 attgctccac cttgaacggc caattcgtat gttcgatcgg tcgaattatt atcatagaca
    43501 taaatatctg cttctggtaa ttctcgttta aagtctgcaa tgactgttga aattgttgct
    43561 tcctcattgt aacaaggaat cagaacagca attttttctt gttgttccat ttttcactct
    43621 ccttaactat agaaaacaaa agctaaatta aaaatacctc ataatcaaag gaaatgctag
    43681 tttttcccgc taaatatcat ttatttaaaa agaaaatact ggaatatatg tttggaaagc
    43741 tctatctaaa aaaccaccca ctacaaaaga aggacatgat acctctcttt tgaatagtgg
    43801 gtgcgtattc gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa
    43861 atttctaata cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca
    43921 tcttctattc gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata
    43981 ggttcctttt caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac
    44041 ttgatatttt caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt
    44101 gaagctaccc cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag
    44161 cttagttcgc tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg
    44221 tgcttatttt accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat
    44281 aagctataat aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat
    44341 aagtctgaga ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt
    44401 caacgaatca aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc
    44461 gcttatatgg aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc
    44521 ggcatttttg gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca
    44581 catatggatg aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc
    44641 gtacctctag gcggctggaa tccttacgtt gtttctgctc agcgttttac acttaaaacc
    44701 tctactggta agaattatcc atgtatttct tcttccgttc ccccacattt attgcgagga
    44761 acaagcggac aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca
    44821 agagaagagg caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa
    44881 acgatcaaaa cagccaacgg aaagaatatt atcagtaaat catgggacaa ccgctatggc
    44941 tgtacaatgg tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg
    45001 attgcaggcg cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat
    45061 aaattcaagc cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg
    45121 aaaaatggca cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt
    45181 ttgatcatgc ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc
    45241 ccttatcaat actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac
    45301 gaaggaatcc caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg
    45361 atgttcagta ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt
    45421 ttggataaat caacagtgaa tacgatcgta tacggaaaat aatgcgatag tgaaactata
    45481 aaatctggca aaagattgct ttttgccaga ttttttttat aaaaagagga tcaatgtttg
    45541 ttagttcgaa agaaaggtgt ataatttaat tgaaaaatac ataaacagaa agtagaggac
    45601 aaagaatgat tatcccaaat agtttagaag aattagcagg ctacgtagaa actggaaaga
    45661 gtgtattttt ctttactgcc ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc
    45721 ctgaaattga aaatgacttt tctgattggc aatttattga agtagaccgt gacaagtaca
    45781 tagatgtagc cgctgaatgg aacatttttg gtatcccaag ttttgtcgtg atccaagacg
    45841 gaaaagaatt aggtcgtcta gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt
    45901 tcctagaaag tgtaacaaaa ggctgacatc tgttaggagg ggtcaagatg aatcaagaat
    45961 ataagaatat tttagtaggt atcgacggta gtgaacaagc acttgctgct ttcaaaaaag
    46021 cggtagaagt ggctcgccgt aataatggga aagtatatgt agcaaacgta atcgatcagc
    46081 aattttataa ctttatgggc tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg
    46141 aaacagccaa ggaaatgatc gaagaatgta aagaatatgg gaaatctgtt gattacacaa
    46201 atatagaagg aattattgca tatggttctg ttcgtgaatc catggcagtc aaattgccaa
    46261 aaaaatatga gatcgatcta atcatggttg ggcagtcagg tctaaatgca gtcgaacgct
    46321 ttatgacagg aagtgtagcc agctacgtga tacgtcattc accttgtgat gtcttgatcg
    46381 tttctgacga agaagaacag ccaagtaatt aagcaagtgg aacttgtacg acctttttaa
    46441 tcaattaact aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg
    46501 aataaatggt gttccagaag aggcttcttc ggaaataaag catgaaaaaa atttcatgca
    46561 gtgaatgcaa ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga
    46621 tttttgctta taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata
    46681 aaggaacaga aaacactgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag
    46741 gtcaagttgt tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg
    46801 gccaagtaag cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag
    46861 gattcgaaga acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa
    46921 catgcgtccc acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg
    46981 gtacagtatt gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg
    47041 ttgcaaaacc aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag
    47101 gggtagatag ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag
    47161 caaaaaaagg aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat
    47221 aaagaggttg tgacaagtct ttgtcacaac ctctttttta ttaattttca ctattttgat
    47281 tttgttttaa tgccgattga tcgatcgtca attcaacagt agttgttttt tctttcgagc
    47341 cttcatagta agtgattttg acagaatctc ccactttttt cttatacaaa gcagattgaa
    47401 gttctacacc agaagaaact tctttgtcat cgatcttagt aatgacgtcg tattgtttca
    47461 atccagcttt ttcagccggt gtagctgttt ggacatttgt cacgatgaca ccgttagtta
    47521 cagatgaagg aatcttcaag atttgttctt gttgctgagt agaaacggca gataagtcga
    47581 ccattgtgat acctagagct ggacgtgtca cttttccgtc tttttccagt tgattgatga
    47641 tattcactac atcgttactt ggaatagcaa atcccattcc ttctacgctt acattagaag
    47701 tagattcaga agtacttgcg atcttacttg agttgatacc gataacttgt ccttcgatat
    47761 taactaaagg accaccagaa tttccagggt tgattgctgc atctgtttgg atcgcattga
    47821 tattgactgt ttcgttcgat tcattcgtac ttgtcacttg tcggttcaag gaagaaatga
    47881 ttcctgaagt gacagaattt gcatattcag atcctagtgg ggaaccaatc gcaatcgcag
    47941 gctcaccaac cttcagagca cttgagtcac caaaagaggc aactgtttcg actttgtctg
    48001 aattgatctt caacaccgct aaatctgaat aagcatctgt tccaactaat tcagctttta
    48061 ccttcgtacc gtctttcatc aagacttcaa gaccttgctg gccatctact acgtgattat
    48121 tcgtgactac ataagcagta ttcccgtctt ttttgtagat cacgccgctt ccttcactat
    48181 aagcttccaa attactatca tctgagctgc tactttcttc ttgctgcccg aatagtccgc
    48241 caaaaccgct tgattggttt tgactttgta agttgataac agaaacgaca gcgtcttgaa
    48301 ctttatctac cgctttggtg atatcagaat ctacattgac tttgacattt tccacaactg
    48361 tttcaccggc agaattctga ttgccgcttg tagcagtaga actattgttg ccagtgccca
    48421 tcgctgcata aaaaatgcca gctgtcagta gtcctccaac gatccctcca acaagcccca
    48481 gacctaactt acgccagagg ctattatttt tacttttttt catctttggt gtcacatttt
    48541 ttctatccat gtgttcctcc tccaattaca ttcatttatc tactgttagt atagtcttat
    48601 ttgttgactt tagtctactt tgagactgtg aactttttat gaaaaacttt aggaaaaatc
    48661 attgttttca gatgaaaata tttgattttc tttttccaca gatactgtgt aaaactacgc
    48721 ggataggatt ggaaaaataa gggataaaac atatccacag cctgtgtata aagtggataa
    48781 attcttataa aacgtatgtt tgcctaatga atgtgatgaa ataaggtaaa ataacactgt
    48841 tttctgtgga taaacctgtg gatgttgtgc ataactgttg gggaaatctt tttaacaaaa
    48901 atagccaaaa taaacatata gacgaaaaaa ttgattataa taaacaaagt gagcatgaag
    48961 accaaaggag agaaaacatg aatatcaaaa ttatctcagt aggaaaatta aaagaaaaat
    49021 acctgatcca aggtatcaat gagtatgtca aacggctgaa tgcctatgca aaaatcgaat
    49081 tgatcgaagt tcctgacgaa aaagccccgg agaatttaag cgaagcgcaa atgagacaag
    49141 taaaagaaaa agaaggggaa cggatcttag cgaaaatcaa agaacaagaa tacgtctatg
    49201 ccttagcaat tgaagggaaa aatcctacaa gtgaatcttt tgctaaacaa atcgaccaat
    49261 taggtatcca aggaaaaagc caccttgttt ttgttatcgg cggctcttta ggactcagcg
    49321 aagccgtcat gaaaagaagc aatgctcaga tctcttttgg aaaaatgacg tatccacatc
    49381 aattgatgcg tctgatcctt gtcgagcaaa tctaccgtgc cttccggatc aatgcggggg
    49441 ctccgtatca taaataatga tatttaagat tgaatgctcc tgaacactaa gttagctttt
    49501 cattgaaatt tatatataaa aaagttaact tgaaaatcgt tgagaatttc aaaaaaataa
    49561 taataacttt attatgtatt caaatttgtt acaa
//
LOCUS       DADGHT010000009        44287 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.009, whole genome shotgun sequence.
ACCESSION   DADGHT010000009 DADGHT010000000
VERSION     DADGHT010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.009"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(501..1055)
                     /locus_tag="JX887_000448"
     CDS             complement(501..1055)
                     /locus_tag="JX887_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAX1256462.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(1181..3110)
                     /locus_tag="JX887_000449"
                     /pseudo
     CDS             complement(1181..3110)
                     /locus_tag="JX887_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(3416..4132)
                     /locus_tag="JX887_000450"
     CDS             complement(3416..4132)
                     /locus_tag="JX887_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAX1256463.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(4133..5956)
                     /gene="glpO"
                     /locus_tag="JX887_000451"
     CDS             complement(4133..5956)
                     /gene="glpO"
                     /locus_tag="JX887_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAX1256464.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(5970..7466)
                     /gene="glpK"
                     /locus_tag="JX887_000452"
     CDS             complement(5970..7466)
                     /gene="glpK"
                     /locus_tag="JX887_000452"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAX1256465.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(7602..9062)
                     /locus_tag="JX887_000453"
     CDS             complement(7602..9062)
                     /locus_tag="JX887_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1256466.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(9052..10347)
                     /locus_tag="JX887_000454"
     CDS             complement(9052..10347)
                     /locus_tag="JX887_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAX1256467.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(10679..11356)
                     /locus_tag="JX887_000455"
     CDS             complement(10679..11356)
                     /locus_tag="JX887_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAX1256468.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(11386..12477)
                     /locus_tag="JX887_000456"
     CDS             complement(11386..12477)
                     /locus_tag="JX887_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAX1256469.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(12578..13012)
                     /locus_tag="JX887_000457"
     CDS             complement(12578..13012)
                     /locus_tag="JX887_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAX1256470.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(13596..15053)
                     /gene="ascB"
                     /locus_tag="JX887_000458"
     CDS             complement(13596..15053)
                     /gene="ascB"
                     /locus_tag="JX887_000458"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAX1256471.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(15050..16945)
                     /locus_tag="JX887_000459"
     CDS             complement(15050..16945)
                     /locus_tag="JX887_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1256472.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(17003..18778)
                     /locus_tag="JX887_000460"
     CDS             complement(17003..18778)
                     /locus_tag="JX887_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1256473.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(18828..20324)
                     /locus_tag="JX887_000461"
     CDS             complement(18828..20324)
                     /locus_tag="JX887_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1256474.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(20518..22140)
                     /locus_tag="JX887_000462"
     CDS             complement(20518..22140)
                     /locus_tag="JX887_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAX1256475.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(22468..23781)
                     /locus_tag="JX887_000463"
     CDS             complement(22468..23781)
                     /locus_tag="JX887_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAX1256476.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(24026..24250)
                     /locus_tag="JX887_000464"
     CDS             complement(24026..24250)
                     /locus_tag="JX887_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256477.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(24270..24638)
                     /locus_tag="JX887_000465"
     CDS             complement(24270..24638)
                     /locus_tag="JX887_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAX1256478.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(24834..25544)
                     /locus_tag="JX887_000466"
     CDS             complement(24834..25544)
                     /locus_tag="JX887_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256479.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(25562..26059)
                     /locus_tag="JX887_000467"
     CDS             complement(25562..26059)
                     /locus_tag="JX887_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1256480.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(26096..26548)
                     /locus_tag="JX887_000468"
     CDS             complement(26096..26548)
                     /locus_tag="JX887_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAX1256481.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(26683..27288)
                     /locus_tag="JX887_000469"
     CDS             complement(26683..27288)
                     /locus_tag="JX887_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAX1256482.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(27738..28358)
                     /locus_tag="JX887_000470"
     CDS             complement(27738..28358)
                     /locus_tag="JX887_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1256483.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(28360..29229)
                     /locus_tag="JX887_000471"
     CDS             complement(28360..29229)
                     /locus_tag="JX887_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAX1256484.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(29252..29659)
                     /locus_tag="JX887_000472"
     CDS             complement(29252..29659)
                     /locus_tag="JX887_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAX1256485.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(29678..30967)
                     /locus_tag="JX887_000473"
     CDS             complement(29678..30967)
                     /locus_tag="JX887_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1256486.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(30994..31296)
                     /locus_tag="JX887_000474"
     CDS             complement(30994..31296)
                     /locus_tag="JX887_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1256487.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(31321..33414)
                     /locus_tag="JX887_000475"
     CDS             complement(31321..33414)
                     /locus_tag="JX887_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAX1256488.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(33903..34667)
                     /locus_tag="JX887_000476"
     CDS             complement(33903..34667)
                     /locus_tag="JX887_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAX1256489.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(34778..35647)
                     /gene="mdcB"
                     /locus_tag="JX887_000477"
     CDS             complement(34778..35647)
                     /gene="mdcB"
                     /locus_tag="JX887_000477"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAX1256490.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(35672..36748)
                     /locus_tag="JX887_000478"
     CDS             complement(35672..36748)
                     /locus_tag="JX887_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAX1256491.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(36772..37365)
                     /locus_tag="JX887_000479"
     CDS             complement(36772..37365)
                     /locus_tag="JX887_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAX1256492.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(37369..39045)
                     /gene="mdcD"
                     /locus_tag="JX887_000480"
     CDS             complement(37369..39045)
                     /gene="mdcD"
                     /locus_tag="JX887_000480"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAX1256493.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(39035..39334)
                     /locus_tag="JX887_000481"
     CDS             complement(39035..39334)
                     /locus_tag="JX887_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAX1256494.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(39436..41082)
                     /gene="mdcA"
                     /locus_tag="JX887_000482"
     CDS             complement(39436..41082)
                     /gene="mdcA"
                     /locus_tag="JX887_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAX1256495.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(41089..42000)
                     /locus_tag="JX887_000483"
     CDS             complement(41089..42000)
                     /locus_tag="JX887_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAX1256496.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            42120..42977
                     /locus_tag="JX887_000484"
     CDS             42120..42977
                     /locus_tag="JX887_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1256497.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(43164..43526)
                     /locus_tag="JX887_000485"
     CDS             complement(43164..43526)
                     /locus_tag="JX887_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256498.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            43872..>44287
                     /locus_tag="JX887_000486"
     CDS             43872..>44287
                     /locus_tag="JX887_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1256499.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDL"
BASE COUNT        12581 a         9525 c         7440 g        14741 t
ORIGIN      
        1 tttgacctaa gtattagaga aaaaaacggg aaaatagctc ctcatatttt gccgtttttt
       61 gagctaatac cgaaggtcag ctgattgaac accgtttaag gaagagattg tgaaaaagtc
      121 gcttagtttc gagtattaag aaaaattttg tgaaaatgga tttctacatt tttgcataaa
      181 tttggcttaa taccgagaaa ctggcttttg aataccgttt aaggaagagg ttgtaaaatc
      241 agcggtttga cctgagtatt agagaaacaa acggaaaaat agctgctcat attttgccgt
      301 tttttgagct aataccgaag gtcagctgat tgaacaccgt ttaccaagag gttgtgagcc
      361 taccatttaa ctccgaatca caagaaataa tttcaaaaac aacttctcct gtttttggtt
      421 cggttggctt attatcgaga agtagctact gggagtctat ttatcaaaaa aaggaatgcg
      481 acataggtca cacccctttt ttattttctt tgaaacatct ttcggtactc gacagcatac
      541 aagacaaaag attgtaaaag accgtaagtg atgacggcaa aaatgactct cacccacagc
      601 gttggtaatt ctgggaaaag cagcaaaagg atcatgccaa catagatgac agcagtcgct
      661 actttgccat accacttcgc tccacttaat ttgatatttt tagatagccc gattaatcca
      721 gctacaaaca taaagccttc ttttatcaag aatagaccaa acaacagcca aagccacggt
      781 cgataccatg ccatagacaa aatcagaaaa agttgtgtca atttatctgc aaacggatca
      841 agcaccttcc ctaagtctgt tacctgatta tatctccgag caatgacccc gtctagataa
      901 tcagacaaac ctgagacaac aatgaccgct cctgctatat aaaatgactg tctcagcaca
      961 aaataaagat aaatcggcag caaaaaaata cggaatatcg ataaaagatt cggaatcgtt
     1021 tgtatttctt tacgccagtc tgtgcttaat ttcattttat cgccctacct cctcagcact
     1081 cttttctttt tattttagct tacacgggga ataaaaccaa tgatttcact gtttttattt
     1141 ttctttacag acactgatat tatgagctaa tttgagataa tcacttgctg ttttcatcgt
     1201 ttactcttct ttcttcctgt cgtttgcgca tttcttttac tagtacttta tgagcttttt
     1261 ttgatcctcg ctctaggtca cgctgccgtt tacgtgtttt ataatcgata aacagactgt
     1321 ctaaatcgta acctgtcggg tacagatctt ctgctgaacg caccagacga acacgctgac
     1381 gaggcacgtg gattattttt ttgtctaaat atacatcaat cgtatcttca cctatatctt
     1441 cataaactaa cgcttctttt tggtattcat tgacaaatat ccgatcacct tttgcaaaga
     1501 gctgacgttc ttttttattc tccttcctat ttgtaactgc tgtcttagga agaaattctt
     1561 ttttctgtgt ccgataggct ttttccgcca agtaacgctc tgcttgatgg atcaatttca
     1621 tcgacatatc cattttatga gcaatccaca aagcttggct ttctcctgtt tcttccaacc
     1681 cgcaactgat atttaggacg aagtgcttcc cgatcgaaag ccatagcagc cggcacaaaa
     1741 tcttcatgat ctccggcgaa tttcttgatt tctccataat gggtcgtggc aatgatcaat
     1801 gccccttgct catacataga ttccatgatt gcgatcgcta gtgcagcccc ttcatttggc
     1861 tctgttccac tgccaatctc atctaaaagt accaacgtat tcctttttat ctttttcaaa
     1921 atagcagcga tgttttgcat atgaccagaa aatgtactca acgcattttc taaattttgg
     1981 tggtcaccga catcgacgaa aatctcatca aagacagcaa gctctgtccc ttcttttgcc
     2041 ggaacttgca taccgaacat cgccatcaaa gtcaataaac cgactgtctt caacacgact
     2101 gttttgcctc cggcatttgc tccggtgata atcaagcctc gatagtcttt accgatttca
     2161 acatccaatg gtaccgcatg ctcaggtaaa aatggatgtc tgccttgctt gataatgata
     2221 tgttccgatt tattgattct aggtgtgctt ccattgattt ctcggctaaa ttttgcccga
     2281 gcaaagatga tatctaacac cgtgatcgtt tcgatcaata aatcgatcac ttcttcgttt
     2341 tctgcgatag caccagtcaa tgccgccagg acttgatatt cttcactgat ttcttcagct
     2401 tttaacaact gatagtgttc attcaattta gaaatcacag ttggttcaat aaaaaccgtc
     2461 gttcttttat ttgattcatc gataatcgtt ccatctattt tatttttata gctggctttg
     2521 ataggaatcg tatagtattc gcctttttga acaatcattg cttcttggat catttctttg
     2581 tttttcggat gacgcaagaa tttcagtaat tttgactgga tttctttttc gattagttgt
     2641 aattgtttgc gtactttacg caaattacgt gacgcgtcgt cactgacttt attatttttt
     2701 attttctggt caatcaactc ttctacattt atcaaatcag gaagatgttt gctataagca
     2761 aacaacaagg gtgtctggta ttgattctta tcaaaaaact ttgtgatcat ccgactgctt
     2821 ctaagaaaat ccgcatattc gatcaaatcg gttggctgca gaatcaaccc ttttttgact
     2881 tgttctgtca gtgcatcgat cctcggcaac cccataaatg gaacatgctg actgctttct
     2941 aagatcaagc gtgcttctct tgtttcttct tgacgatcca agacagtttg taggtttgtc
     3001 gagaccgtca tatcgctgat tcgttttttg ctatagtttc caattgctct tgcttggatt
     3061 tcctttttga tccgatcaaa ttgtaattga ctaatcattt cgttgtccat attctctcct
     3121 tttcttgaag agatacctgt cccaaaataa ataagggcct agagataaat aaaaggatag
     3181 aacacagctt aaaaaagtca tgtcctatcc ttattagaat acaaagatat tgttttcctg
     3241 acaggtaccg tttcataagc acaccaaata aactttgttt attggctatt cgacttactg
     3301 attagatacc agctacactc acaaaacata ccccattctt ctaggtctta tttattttcc
     3361 acttaactat agcaagacac attttggttg tcaaacttta gtatgtttta tagatttaca
     3421 ccattaatga atagacacct accgcgataa ttgctccgat cattggacct gcgattggta
     3481 cccatgaata tgcccaatct gaagttcctt tattagctat tggcaatacc gcatgtgcta
     3541 atcgaggacc aaagtcccga gcagggttga ttgcatatcc tgttggccct cctaatgaaa
     3601 gaccgatggc taagatcaat ccacctacag cgaatacgtt cgttccaggt gcaaattcgt
     3661 tttgtccaaa agctagcaac ccaagaacta atacaaatgt accaattaat tctgtgatca
     3721 catttgctgg ataattccgt atagcaggac ctgttgcaaa cgttcctaaa atcgcgcttt
     3781 catctttcgt tgcattccaa tgtggcaaat aagaaagcca aacaagaatg gcccctgcaa
     3841 aagctcctaa aacttgcgca atgatgaaag gaacgacaag attccaacta attgcccctg
     3901 tcatcgccat agctagagag actgcaggat tcaaatgagc tgggcccatg aatccagaaa
     3961 tatagacagc cattgttaca gcgagtcccc aaccaaatgc gatgacaatc cagccagaag
     4021 cctgtgcttt acttttgttt aaattcacag ccgcacacac accatctcca agcaaaacta
     4081 ggatcagtgt cccaataaac tcccccatga tttgagtcat atcactgttc atttatttct
     4141 ccccctttag ttcccgcaga tctgattctg caatcaatgc ttctaaacgt ttagtctgtt
     4201 gcgccttctc ctcttctgtc cattcaaaat atccagcaat tgcatcgatc acaggttgct
     4261 tgatctcatc aagctgatct cgttcaaaca acagatgatt tgtacgacga atgagataat
     4321 cgcctggggc caaaaccatt tcttcttcta aaccataacg taaccgagct gactcagcga
     4381 gactcaaacc aggataaggt gccatttctt ttgctaattc aaagatacgt cgggcattag
     4441 tcccgtaaaa atcagcgata taagtagcat cttcttcctc taaaccggct gctactcctt
     4501 cttttgctaa ttctgtcact gtttcttcta atttagttgg atcgaagttt ccacctgaaa
     4561 tctgatattt tttagagtcg atttctttcg tctctattcc gtattcttct tttaataatt
     4621 ggcgtatcaa tcgcaaagct ccttctgcca tcttacggta atcggtgatt ttcccaccag
     4681 ataaagtcag caaaccatct ggttctcttt ctaaagaact acctctggaa atcgtagaag
     4741 gtgctttttc atcacggctg ttttccaaat ggttcaacac gtcttctact tcagcacgag
     4801 aaactttgtt ttccttatat tcacttactg tatcgacaac tttattgaag ctcttgtctg
     4861 aaatcgatcc attatctcca ccattgtaat cagaaccaga attaccaatc aacagtggac
     4921 gaagtcctgc ccagcttgct tcgatatcat tcaatgtgat atttgcttct ggatagcgat
     4981 gattgatcac atccaataga taatctacat cttcttgtgt gactttcgga tccgtaaaat
     5041 ctccttggta atccgtatct gtcgtaccaa agtaagtctt gttttctctt ggaatagcaa
     5101 aaaccatccg cccatcttgc tttcctgtat cgaagtatgt gggttgcggt acaggcagtt
     5161 ttttcgcatc tacaactaaa tggatccctt tagttggacg cattttagga gagactggac
     5221 gcgtaaaatt caagtttcgt actttatcta cccaaggacc actcgtattg atcactaatt
     5281 ttgctttgat ttcgatcact tcatctgtca gcaggtcacg agctttgacg ccaacgattt
     5341 gatcgccatc atataaaaag ccaaccgctt tcattttact tactagataa gccccatctt
     5401 cggcagcctt tttgatatta tcaatcacta aacgggcatc attgttgcgg aaatctagat
     5461 agacacccgc gccttttagc ccttcttttt tcaaaaacgg ttctctttcc aatacttctt
     5521 ctggtgtcag cgtataattc tcatatttgg ttcctgtcac atttgccagt ttgtcataaa
     5581 ggtccattgc tactttgacc gagaacatat tgaaggttgt tgctccttcg ccctcataga
     5641 ttggcaaaag cattggatct ggttttggga tgtgtggggc aatactttgt acgactgcac
     5701 gttcaccaac tgtgtcagct actacttcca catcaaatgt cttcagataa cgaataccgc
     5761 catgaacaag tttggtcgag cgagaggaag tcccttctgc aaaatcctgc atttcgatca
     5821 atcctgtttt gattcctgat gctgctgact ggactgccac accggcacca gtgattccgc
     5881 caccgatgat caacagatcc aattcttctt gctgcatttt ttgaatgcta tcttgtcttg
     5941 tcttgtttga aaacatatgg atttcctcct tattcaaatg cttgggtagc ttttactgct
     6001 tttttccaac cgttgtaaag tttttctcgg cgctcttcct ccatttgaac ttcaaatagc
     6061 ttgccagctt cataaaattc gcggatctcg tctgtatctt tccaataacc gacagctaat
     6121 cctgctaaaa atgctgcccc tagcgccgtt gtttccaagt tttctgctcg ttggatcggt
     6181 acattcaaga tatctgtttg gaattgcatc agatattcat tgtttgctgc accgccatct
     6241 actttcaata caggaatctt gattccagtg tcatcttgca tcgtatcgat gatatctctc
     6301 acttgataag caatcgactg taaagtagct ttaatgatat cttcttttgt cgtaccacgt
     6361 gtcaagccaa acatagcccc tcgtgctgcc tgatcccaat aaggagcacc tagcccaacg
     6421 aatgcaggaa caacataaac ctcatcttcg cttgtagagc gtttcgctgc gtcttctgaa
     6481 tcgctagctt tttgcaacat ttgaagtcca tctctcagcc attgaatcga agaaccagcc
     6541 acaaaaatac ttccttctaa agcatagtaa acctttccat ttatgccgta accaattgtc
     6601 gtcaataaat tatttttgga taattgcggt ttttcaccgg tattcatgac aataaatgaa
     6661 cctgtaccat aagtattctt gaccatgcct ggttcgaatg ccatttgtcc gaataatgcg
     6721 gcttgctggt ctcctgccat ccctgaaatt ggtgcttcgc ttccataaaa atgataacct
     6781 tgcgtataac cataaacttc tgagttagaa gtgacttttg gtaacatcac tcgaggaata
     6841 tttagtaaat ctaaaatctc ctgatcccaa tctagctgat ggatattgaa caacatcgtc
     6901 cgactggcat tcgagtaatc agtaacatgt gcttgtccat cggtcagttt ccatactaac
     6961 caagaatcga tcgttccaaa catcaattcg cctttttcag ctcgttcttg cgcgccttct
     7021 acatgatcaa gaatccagcg tatcttcgtt gctgagaaat aggcatcgat cactaaccct
     7081 gttttttcgt ggaaaaattc ttgatagcct tcatttttta agttatctgc aattccagct
     7141 gactgtctgg attgccaaac aactgcatga tagattggac gtcctgtatc tttttcccat
     7201 attactgttg tttcacgctg gttcgttatg ccaatcccag caatctgatt tggtttgatc
     7261 cctgattcga tgaacgctcc ggcaataact gactgtacag aattccagat ttcatttgca
     7321 tcatgttcca cccaactttc ttgcgggaaa tattgcgtga actctttttg agaactgccg
     7381 atgtgtcttc ctttcttgtc aaagataatt gctcgtgagc tagttgtacc ttggtcaatc
     7441 gccatgatat acgttgattc tgtcattgtg attccctcca ttatatgcaa acgctttctt
     7501 taactactct tatcatacta ctgttttaaa aaaagaaact gtcaaaattt tattcttttt
     7561 ttcttttttt gacagttttt tattatgaag ctatttttta atcaattctt ttcttttttc
     7621 agcgtctcta ttcttctttt caatcgaata atgtcgtaag gtgacgcaaa ttctgacaga
     7681 taatattcac actgtttttt gtttctctgg caaaatgtga tcaccaaatc atattcttta
     7741 ccttcttcat aacttccaat ctcaataccg ccgattcccc tcagttctct gatcagatat
     7801 tgttgaaaag caatacgata aatcggcaga ctttctaaat cgattccaat cactactggt
     7861 tttgcaatat aaaaatcgat catcaaaaga acattggcat actggatcat caggtaacta
     7921 agctcactat cttcagctct tttcctcggc aattgctgca ccgctgtttc ctgtaatttc
     7981 gccagtaact gtgttaagga atgcccgagc attttctgct gctgttccaa aagccgatca
     8041 cgctcataga cttcgatctt tccaacaaag aaaaaccatt cattgttgat ctgggaaatt
     8101 tggtagccta ctgccttttc ttctttgatt ttcaaacgac gaggacgata atgccataac
     8161 atcgtttccc gaatgtaagt atctaaaaca gcggttggta actttttgct ccgtgtcaaa
     8221 tcatactgat aaaatatttc ttcgtctact atcgaaaaag aaacaaaaaa gctgtaaaac
     8281 atcattgttt cgtatacatt cagttctgct gctgttcgac taagatgcat cacgatgatt
     8341 ggatcgattg cttgataaag ccggtccgac tgatagagta atttcttttc tttcaaagtt
     8401 gcgtacgtac ttttttcatt caatagtctt tttttcgtaa tcccgagcca gcaagcaatc
     8461 tgtgcttctg ctgatgccgt aaacgttgtt tctaatacac ggtccaatcc tagaatgaac
     8521 ggtctttttt ctggtgtatt ttgcaaaaaa agcggtcgct gatcttccgg gatatattgg
     8581 aatagttcat aataaaaata tcgtatctgt agctcttctc cgtataattg accgtttttg
     8641 atttgtaatc caaattcctc taagagctgg ttcaattctt tgatctttcg aaaaacagaa
     8701 gactcactga tattaaacgc tgtcgctaat cgaacgatgg atacttgctg atgttctaat
     8761 aaatagacga gcatcttaaa cttcaagctt tcctgcaata aaaacaatag aattttttcc
     8821 aaacttacat cttcgtccaa cacaagcagc gcctgatact catttcgctg tacttctact
     8881 tttttttcca tcattcggcc aatcaattca atatcttcca aatattgatc aaacgaggct
     8941 tttgacagtt ggacatgctc tctcaaacca ttgatagagg ctgttccccc ttgcagaaca
     9001 aggtttcgca aaatcaggat ctgtaactgc tcttttcttt ctaataatgc ttcaatcttc
     9061 ataggcagta ttcgccacct ttgaccacac catatctggc acacggtatt ctggctggaa
     9121 aaatagctca tgttcttcta actgttcaaa cgtccatcct tcttctactg caattgtcag
     9181 ttggtcaaga aggtggaaca tctctttttt gctttggagc tgtgctccaa gaatcttttt
     9241 ttcagaatca aatagaaatt tgagtttaac tttgctttga tttattgctg taagcttgta
     9301 gtctacgtat cctgtttcaa ttttttgggg ataaaaaatg ctctcttctt ctgtcaaacc
     9361 tacgcttcct aagaaatagc caaaccactg attgccgact ggacgatagg ttccctgatc
     9421 ctttgtctgt gagccactaa ttgtcttgct gacatttcgt gctgtacgga cagcgttatt
     9481 tactagagaa acatacattt tttcatttgt tggacgaaaa gttacttgga tcgcatcgcc
     9541 aatcgcataa acgtcttttt gagacgtttg caagtagtca tctacccaga tcgttccatc
     9601 atcattcaat gttaattgtt cttcccacat ctgattgtcg ggacgagaat gattagccag
     9661 caaaacaaga tcatagttct cctttctttt ttccgtctct acaatagcgg tttcattttc
     9721 ggtcaaagac acaacttgtt cttctaaaaa aagtgaaagc ccttgatttt tcatttcctt
     9781 tactaacggt tctgtcattt caggatctag ataacgaaaa agaattgact ttcggctttc
     9841 gtaaagatgg atttgttttt ttcttgatgc caacccttca gctatttcga ttcctgcttg
     9901 tcctgcacca ataattgcaa ttttctttgc attcatgatc ttttgctgaa gagccgttac
     9961 gttttgtatc tttttaactg ggtgaataag cgttgattct gcagaaatat ttcgaaactt
    10021 ttgatttgaa ccagtcgcta gaatcaaacg atcaaaatcc aatttttttc ctcctgctaa
    10081 aacgactttt ttttctttca atcctattac tgtcttttct gtgtaaacat ggattcgata
    10141 gcggtcagtc agttcttctt tcgtgatcca agaaagttgt ttttcactgg taacctttcc
    10201 ttttaatatc aaattgaacc cgctgggaat ccatcctaac ttcgattgct tttcaatcaa
    10261 atatatttca cttgttggca tcaattggcg aagataaata gccgcatgaa tccctgcaaa
    10321 cgacccgccg acaattacaa tgttcatctg cattcctctt tcttataagg tgttctactg
    10381 ctaacttctc aatcagaaaa cacagtattc ataactcgct ttcaacctta tgatacatag
    10441 cgatgcagca gaatcaaccc tctccatcat accgtgttct aggtctgctt ctcaataatg
    10501 tactagtgga cctaattgaa gagtatcatt tctgaagaga tgtttcaaaa aatgtactct
    10561 tataaaagaa aaaaactcgc cttttacgta cctctgtcca aataggaaac agaaaagaac
    10621 gaaaagacga gttttagcgt gtgtaatgta atagttagaa tagacacatc atttattttt
    10681 aattctttaa tgcttcaaca actgcttcgc ctaattgatg agcagattga ggattttgcc
    10741 ctgtaagaag ccgcccatca atttgaacca cttctgaaaa agctgctcca gactgatagt
    10801 ttgctccttt ttctttcaaa gcatcttctg ctaagaatgg tacttcattc gttgtaccat
    10861 ttgcttcctc ttcttcatta ctgaacccag tcactgtacg tccagctaaa atagattttc
    10921 cagactcatc tgtaactggc aacaatccta caacaccgtg acaaacagct gagaccagcc
    10981 cttcatttcg atagatttgt gaagcgactt tcccaagatc tattgcttct ggaaaatccc
    11041 acattgttcc gtggccacca gcataataaa ccgctgcata atcatttgca tccacatcat
    11101 caggacgtaa ggtatttccc aaggcccgat ttctgaaatc ttcatcttca taataggccc
    11161 aatcgatttc atccatattc aaaacacttt gcggttctaa aggtacatat ccgcctttag
    11221 gactgacaaa atctgcatcg atcccatttt ttactaatac atcataaaaa tgagtcagtt
    11281 cacttaacca caaacctgta ggacgctcga tcttttcgta cttttctaca tttgttaata
    11341 cgatcaatac tttcattttc ccatcctctt tctataaaaa ttgcgttatt gataacgtgc
    11401 tttcaagaaa ttatataatg ggcttggcaa ataaagctct ttatatgctt cttcaaaagg
    11461 tttcgttaca aattcatcct cacggttttc caataatttc tctgcccagt caggatcgac
    11521 gatcatttgc tgtccaattg ctgcaagttc tgcatatttc aatacctgct ctacatcttc
    11581 gcgattgcgg atcccaccga caccaactaa agggatcttt ccttgaatcg tgttatggac
    11641 cacttcaaga atcgatttat cgttgtattt atcagaacga gctattcgat catacatatt
    11701 taatgaaaca tgcagataat ctagttttga ctcacgtaat cgttcaagaa gccagatcgt
    11761 gtcttcaaaa cggatacctg gtgtttcata ttcttctggt gagaaacgat accctacgat
    11821 gaatggtttt ttagcatatt gttcaaccgc tgagaaaacc gttgttaata attcttcaat
    11881 aaaacgataa cgattttcca agctaccgcc ccattgatcc tctcgtctat tcgaatgcgg
    11941 agagaaaaat tgttggatca aatacgtatt tgctccatgc aactcgattc catcaaatcc
    12001 tgattcaatc gctctacgtg tggctttgcc aaatgcttgg attgtttcaa cgatttcttc
    12061 ttcactcatt gctcgtggtg tttccgcatc aggacgtttt gctgcaactg cacttgcaga
    12121 tacaggctgt tctccagata aagttgctcg acttgtcatt cgtccaccgt ggaaaatctg
    12181 aataatcgct tttgcgcctt ctccttggat tgctttcgct agctcactta atcgaggaat
    12241 catttcatca tgagcgatgc tgagttcacc tggccagcct tttccgatat cttggacatt
    12301 tgcagcacca gtaataacag caccaagacc tttagaacgt tgtttataat aagtgatctc
    12361 atcttcggtg atcactccat tgaaaaagct gagttgtgtc gtcataggcg acagcatcaa
    12421 tcggttcttc aattgaactc ctgaaggtaa agtaattgat tgatcaaatt gtgacattgt
    12481 cattcctccc ataattcgct ctgattaacc tatcgagaat catctatcat taaaccactc
    12541 gattagttgt acatgcaact aatttgctta aaaaatttta ttttttttgt aacttatctg
    12601 ttgcatcatt cattgtctgg gctaattctt tacttgcttc atttcccaaa actgctttgt
    12661 atgactgatg aagttcttcc cagctaccat cgacttcctt agcaaattgg cgtccttgtt
    12721 ctgtaagata aactaatgac aagcgacctt cgctaactgt tttgacgtat cctttatatt
    12781 ctaatttttc aacaaaacga gcaatcgttg atggggcgga atagagcatt tgtgcaatat
    12841 ctttttgtgg tattccatct ttttctttta atatcaataa aataaaacca taagttggtg
    12901 ccagacctgt ccttctaaac gcttcatcag ctaatttatt caacatgcga tctagctttt
    12961 tcacgctaaa gaaaagacat tcatctaacg ctttttcaat tggcttttcc atttcatccc
    13021 ctccattggc gtacatatca tagtatgatt tttatttttt gtcaaaaaac acggaataat
    13081 gtccgcctcc tctgtctaga tttgaaaaaa agaagtagcc atcttcaaag aatttcggct
    13141 tgttttcgac aaaactcctt ctggaacacc gtgaatcaga ggttgtgaaa aagtcgttta
    13201 gttttgagta tgaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaatttgg
    13261 cttaataccg aaaaactggc ttttgaacac cgtttatatc agaggttgtg aaaaagccgt
    13321 cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt gtcgtttttt
    13381 gagctaatgc cgatggtcag ctgattgtac accgtttatt gagaggtcgt gagcctgccg
    13441 ttgaactccg agtcacaagg agcaatttca aaaaacagct tctcatgttt tatgactatg
    13501 gtgacttgtg atcgaggagt tggcaggaga atactgttta ttcgtaaaga aggggctgtg
    13561 acaagacttt tgtcacagtc ccttatttcc ttttattata ggatttcgcc atttgattgg
    13621 atgacttgtc tgtaccaatc aaatgatttt ttctttaacc gtttctttgt gccattccct
    13681 tcgtcatctt gatcaacata gatatatcca taacgttttg acatttgtga agtagaagcg
    13741 ctgacgatat caatgcagcc ccacgacgta taaccaaata aatctactcc atctttgata
    13801 gcttccttca tctgctcaat atgctgcttc aaatagtcaa tgcggtaatc gtcttgaacg
    13861 gttccatctt cttctacttt gtctatagct ccgagtccgt tttcagctat gaacagtggt
    13921 ttttgatacc tatcatataa ttgattcaaa gcaattctca aacccttagg atcaatctgc
    13981 cagccccatt cacttgatgg aagatacgga tttttaattc ctccagttat taagtttcct
    14041 tggacccctt cccaattttc tggatgagca ctgactgcac tagacatgta gtagctaaaa
    14101 gaaacaaaat caacagggta ggctgctaag atttcttcat cacctacttc tatttttaag
    14161 ttgacacctt tttcttcaaa cattcgttgc gtatacgctg gataatatcc tcttgcttga
    14221 acatcactaa agaacaaaga agttctttgc tgctcaattg ttttttgaat atcatccgga
    14281 tcacaagaat acggaacaag aagctgatag ctgatcatac aaccgacttg tgaacctttg
    14341 ataatttcat gacaagcttt tgtagctaaa gcacttgcta taaactgatg gtgtgcacct
    14401 tggtatttcg cttgttccaa atggggatgg ttttcttcaa ttactcctac gctaacaaaa
    14461 gggtgatgtt ttacacagtt gatctcattg aaagtcatcc aatattttac tttattttta
    14521 tagcgtttga atactgtttc agcgaaacga acgtaaaact gaataagctt tcgattaggc
    14581 catccaccat attctgtaac caaatataac ggcatttcat aatgggaaag agaaacgact
    14641 ggctcaatcc catattttag acattcgtca aacacttgat cataaaaaaa taatcccgct
    14701 tcattgggtg tttcttcatc accatgagga aaaattcttg tccatgcgat agacatccga
    14761 tagcatttaa aacccatttc agcaaataaa cggatgtctt ctttaaagtg atgatagaaa
    14821 tcatttccgt gtcttttagg ataataatac ttgctgttgg gatcctgcgc cgcttttact
    14881 tgctgatgcg tcatcatatg ccattgatct gtccattttt ctttaggtaa atcgctgtcg
    14941 aatgtataca catcagacac agataatcct ttttcatcta catcccatgc accttcacat
    15001 tgattggccg ctgtcgctcc gccccataaa aatccttctg gaaatttttt catatcgatc
    15061 cccctaaact tgctagtttt cttgtttgat tatttttctt atgactagta atgatatttt
    15121 tgaatctact actatttgta acaataacca ttgtggtcgg atcatatccc tctttgatta
    15181 attcttgcaa atctacttcc atcaataaat cgcctttacg tacttttttt ccatcagata
    15241 ctgcactttg aaagtatttg ccatttaaat tcactgtatc aataccgata tggatcagta
    15301 tctctgctcc ttcttcactg actaccccaa ttgcatgttt cgttggaaaa actgttgaaa
    15361 cttccccgtt tacagaactg tagatttttc cgtccgttgg aatgatcgca aacccttctc
    15421 ctaaagatcc actagcaaat gttggatcgt ttacttcaga taaatcaatt atttcacctg
    15481 ctgcaggagt acttaacact atatcctttg aggattcttc ttcgatttca tccttgtagc
    15541 cgaaaagaaa agttagcata caggaactga tcatcgctaa gaaataacta gcaactagcc
    15601 aaacaaatcc ttcaccaata taaatcggga aagacaaaat acttcttgta gcaactgcca
    15661 aagcaccggc tcctgcggca ccagctactc caccaaatat agctccacat atacaagcaa
    15721 tgtaaaatgg tcgtttatat ttaagagtca caccataaac agcaggttca gtgattccaa
    15781 ataatgctgt gataaatgca gataaagata aactttttac tttcttattt ttcgttttca
    15841 aaaatacccc aagtactgct cctgcttgcg cagctacggc agtcatacat gctggaccta
    15901 gcgtatcacg accgtagaaa gaaagattgt tggtcattac tggtacaagt ccccaatgta
    15961 acccaaaaat cactaacact tgccaaaatc cgccgataac agcaccagat aaaacagggc
    16021 taaagttata aacagctaaa tatccagctg caatcagctg acttgcataa tctgcaattg
    16081 gacctacaac taataaaata attgggacca tcacgatgat acaaatgaat ggtgtcaata
    16141 aatttcgaat actttcgtgc aagcttttgc gaatcttagg ctcaatataa gaaagaaccc
    16201 atacagctaa aattgctgga ataaccgtac ttgtatacct tgctagaatc acgggcatcc
    16261 ctagaaatcg caaggttatg ctatcactat atgcactgac aatcgtagga taaacgagag
    16321 ctgctgcaat aaccatagcg atgaaacgat ctgtattgaa cttttttgca gcagtatatg
    16381 ccaaaaatat aggcaagaaa tagaaaaatg catcagctgc tgcattcaaa atgatataag
    16441 ttcctgattc agtagttaat aaattcaaac tcgtacataa ggcgagtact cctttgatca
    16501 aaccacttcc tgccaagacg cctaaagtcg gggcaaaaac agcggcgatc atgtctataa
    16561 aagagtttaa aatgcctttt ttctcagttc ctctctttcc actagatgca tcatcttcta
    16621 gtttcatttg tttggataat acgtcataca cttcatttac tgcatttcct actacgactt
    16681 gaaacattcc tccagcttcg actacagtga tcacaccttc tagttgctct accttctcct
    16741 tatctgcctt cttattatct tttagggtaa agcgtaacct tgttgcacaa tggtaaacat
    16801 tgctgacatt ttcttcgcct ccgacaaatc ggacaatatc tttcgctaat tgtgaatagt
    16861 ccatttttac ttcccccttg ttaattaatg ccgtagcaat ccttcttaca agataagtat
    16921 agttcttaga aaacggtttc tccattcaat tagtacccct tctaatagcg aacgaaactg
    16981 tacaatagtg tgtatggttt acttagccga gcaaatcact cactgcttga aagaaaacaa
    17041 gtatatcgtt tctcttatag tcaaaggaga caaaaaaaac acgcttgatc ttcctttgct
    17101 gatgtataag tggtatctca agctgatact ctgtgatttt tgtttctact tggcttttga
    17161 taagacagca caacaaagtc tcggcattta acggaagcat aactaggtca gaactaggag
    17221 agattagttg ctgaatggaa tctatctttt tatggatttt tatttgattt tcttctttgt
    17281 agtaatgatc aagcagtttt gttttctttt tttcttcaac tatggtcagc ttttcacgca
    17341 aaatctgata aatctcccaa gattcaaact catctagaac actaggtaga taaatcaaat
    17401 catcccactc aaaaataagc tcttgctcag tagtcaaaat tgcatcatat tccgttattt
    17461 tgtttgattg atttttgaaa agatacactg gttctatccg gcattctttg atccacatgt
    17521 tcatactttg ttgaatctgt ttttttagtg tattcaaaat actaattggc tggttactaa
    17581 caatcagtat ctccccttgt tttcgaaaag gattcaacgc ttcggcaaga tacaaaacaa
    17641 aataagcgct ttcagctaaa ttgggacgta attgaaaatg tattgggaag aaacgccgaa
    17701 ttaaataaat ttctaaagga taacgggaga tgatcttttg tacaaaatga ttcatggtat
    17761 tatgtccggc atccatcctc gttttcattt gtttgatatg ggttagcaaa aattctgttt
    17821 catggaacaa taacgaaaca ggaagatcta aaaaacgaat aatcgtttgc tcaaatgctc
    17881 ttagattctt ctctatttct ttgttttttt catcattaat catcaaataa tttaactcta
    17941 atagtcgatt ttcaattgct tgtttttctt gattggaaaa agaatagggt agttctgatg
    18001 ataacttttt tgtgagggtc tctaccatcg gaataaataa tgtatacctg tttgtttttt
    18061 ctaaaagttc ttctcttcga agaatggtca aaacgagata ccgagaaaat cgtatgaagt
    18121 cctctcctga aacaatataa ttatatgata taagaacctc ttttaatgtc ttttggacag
    18181 tcggcatgat attggaaaaa attgtactga tttgttgagg aaaccttgcg tgttggatca
    18241 ccgtttctgt tccaacaaga gataagaaaa ttctttttga attttcttca gcaatgattt
    18301 ttagtccttt tgtcgacgaa acttccagtt ctaatttagg attgcgctcg atccaacgca
    18361 aaatcgtttt tatttgtaat gatacggctg tttttgaaag aaagaaaatg tctgctatct
    18421 tttgcatact gacataccct ttttgaaaca ataagtacgt cacaatagtt gaagctcgga
    18481 aatccatgct ggaatagatt ttatgtttcg tcacctcttg tatgatttgc tgtttagttt
    18541 cagattcaat tgattctaaa aaataacctg aacgtttatt tgactggata atgattttct
    18601 tctcgtagat agcaagcata tttttgattt cagtttggat cgttttcttg ttggtaccta
    18661 aagcttcagc taattcttcg cttgttatcc aatgattctt atttcttaat actacaagaa
    18721 tttggagttg tcgtttattt aagtccattt gcttacacct cctctttgtt ataaacatac
    18781 aggaaaaacc tctcaaatga caatagtcac ttgcagaggt ttaaaaatca tttgaagaaa
    18841 gatctatatt caaggttttt accattagac tggataattt gtttataata ttcaaaacta
    18901 tcttttttca atctcctaaa gcttccgctc ccatcatttt gtctatccac ataaataaag
    18961 ccatatcgct tcctcatttc ccctgttcct gccgatacga tatcgattgg tccccaccat
    19021 aagtaaccaa tgatttggca accatctttt attgcctcag caatttcctg aagatgtatt
    19081 tttagatact cacaacgttt tggatcgtgg attcgattca attcatctgg tgcttcatct
    19141 agtccaatgc cattttcaac tatgaataat ggtaattcat aacggtctgt caattcattc
    19201 atgacataac gaaaccctag aggatcaatt ggccaactcc aaggttcggg agatttttcc
    19261 ttcaaaaagg gattatcgaa accatttgct ccgccagtat ctacgcgcat ttctgcttct
    19321 tttttataga cagcgctacg ataataacta aatgcaatat aatctgccgt gttagcttgc
    19381 aagcactgtt cgtctccatc taacattact ggtgcacagt cttcttcctt ccatgtcctg
    19441 taaatataag ctggataatg ccctcggcac atgacatcgg agaaaaacca tgaattgcgt
    19501 ttaaattgca gtgaaccaaa tacattctct ggatcacagt catatgcata agtcgctaat
    19561 gcagaaaagc tacacataat acccatctta gcatttggat cgattttctt taataattga
    19621 gtagcacggg cgttcgctag aaacatatga tgacaggctt gataaatcac tttttttgtt
    19681 agtgtagcaa tgggttcaag tttatctcta gcagggaatg taaccaatcc agcagctgca
    19741 taaggcatac gaaaagcatt attgatctca ttaaaggtca tccaatattt cactttccct
    19801 tggtagcgtt caaagacggt ctgcgcataa aattcaaaaa agtcgattaa ttttcgattt
    19861 tgccaccccc catactctcc taccaatgct aagggggttt cataatgact aagagtaatt
    19921 actggctcga tatcatatcg atttaatgta ttgattagtc tgtcataaaa tacgagacca
    19981 gcctcatttg gcttctgttc gtctcctctt ggaaatattc gtgcccatga gatgcttgtt
    20041 cgaaaagctt ttaaacctaa ctccttcagt aaacgaatat cctcttcaaa tcgatgataa
    20101 aaatcaatcg cttcatgaga aagataatgg agtgattcgt ctaaagcaat ctcccaaatc
    20161 tttttttctt cattccactg aatactagga tgctggttca tgatcccgat aagcgtatct
    20221 gtcacattag gtaatttgcc gtcttccaac catgcacctt cacattgatt agcagctact
    20281 gctccgcccc ataaaaaatt ttctggaaat atttcctgat ccataactat ctctcctcgc
    20341 tatcaacaat ttcttacttg aagtatagct cgattcatca aaacaagata ttctaactat
    20401 ttcggcagaa gagaagaaaa aaattgaatg ctactcttca tttttaatat ttatatataa
    20461 caaatacata agacgatccc cgaaagaaaa cactcgttaa ccatctaagc aaacgattta
    20521 ttttacttcc aacacaaatg cttcataagg tcgtaaatca actttgccgt ctggtaactg
    20581 tttcagagga taatttgaca caataaccct taaagcttca cgtggaatag tgaacgtctg
    20641 cttttcactg gacatattac aaataacgag ccattgctgg tcttcatata tgcgagaata
    20701 ggcaaagaca tgctcaggcg tcttttccac taattcatag tctccccaga cgatgatgtc
    20761 atgttttcta cgcaaatcga tcaatttctt gtacatataa aaaacagaat cttgatctgc
    20821 taacgcttct tctgcattga tttctttata atttggattg actcgaagcc atggaattcc
    20881 agtagtaaac ccagcatgtt cacgggcgtt ccattgcata ggcgtcctag cattgtctct
    20941 tcctttcgcc ttgattgatt ccaagatttc ctcttttgta aatccagaag aaatcctttc
    21001 gttatacata ttgattgtct caatatcttt tgcttccgcg atatcatcga ttgggcaatt
    21061 cgtcatgcct aactcttctc cttgatagat ataaggggtg cctttcatca tatggagcaa
    21121 gatagcaaac atcttggcac tttcttttcg atacacatcg tcatttcccc aacgagaaac
    21181 aattcgcgga agatcgtgat tattccaaaa taaactattc catccttcat cacctaaaga
    21241 tgtttgccat ttggataata cttttttcag ttcagagata ctcaagggtt tcaaatccca
    21301 tttgtctttg ccttcttgct gatctaatcc tatgtgttcg aattggaaga ccatggataa
    21361 ttcatttctt ttaggattgg aataaagttt agcgatttcg gtagttgctc cccatgtttc
    21421 gccaacagtc atcagatttt tgtcaccaaa agttgcttga ttcatttcct gaagatactc
    21481 atgcagttta ggtccattac ttgtgatttc tttatccggt tctttgccaa tcatatcgat
    21541 cacgtccata cgaaagcccc caataccttt atcgatccag aaattcatca tttgataaat
    21601 ctcttggcga acctgtttat ttttccaatt caaatcaggt tgacgcttgc tatacaagtg
    21661 cagaaaatat tgccccgttt tttcatccaa ctgccaagca gaaccactga atattgagcg
    21721 caatctatta ggctcttttc cattgaccgg atcacgccaa atataatagt cccgataagg
    21781 attttcttta tttttacggg cctcaatgaa ccacggatgt tcatcagaag tatgattcac
    21841 caccagatcc atgatgatac ggatatttct tttctttgct tcttcaatca gttcttccat
    21901 ttcttccatc gtaccgaatt ctgccatgat tgcttgataa ttactgatat catacccatt
    21961 gtcatcattc ggagactcgt atactggaga aagccaaatt gcatcaatac ctaaatacgc
    22021 cagataatcc aacctggaaa taatcccccg caaatctcca ataccatctt gatttgaatc
    22081 ttgaaaactt cttggataga tttgataaac aactgaatgg tgccaccatt tttgttccat
    22141 gattttcctc ctataaatgg atgtttctat tttttgctta atcatttatt ttagtctctc
    22201 tcactaaaaa ttgtaacgct ttcaaatagc tattgcacct tgttatcggt aacagaataa
    22261 aacaaaaaaa cagctgagga aattccctca actgtttttt gaaaggattg atttatgcag
    22321 ggaagaatgc tgatttcaca acttctttat aaacggtgtt cactcagctg tcccttggta
    22381 ttagctcaaa aaacggcaaa atataagaaa ctattttttc gtttttttct ctaatactca
    22441 ggccagaacg ctgatttcac aacctcttta tttcacattc aatatccaca tgaatcccac
    22501 aaatacaaag aacagaccat acatgattgg agatacttct tttcctcttt tagctgctaa
    22561 catggtaatt ggatagaaga taaaacctaa tgcaatccca tctgaaatac tataagtcaa
    22621 aggcatgccg atcaagatca agaatgaagg gatcgcaatc tctaagtttc cccattcgat
    22681 ttgtcgcaaa gattgtgcca tcaatactcc taccataatc aatgctggtg cagttacttg
    22741 tgaagtaaca actgatagta atggagaaaa gaacaagcct aacaagaaga aaatccctgt
    22801 agtaatagct gtgatacctg aacgtcctcc aacggcgata ccagctgatg attctacaaa
    22861 tgcaccaaca ggagaagtac caaataagga acccgcaagc atagctgttg aatcagaagc
    22921 taaagctttc cctacacgag gcatcttgtt gtctttcatg aaacctgctt ggtttgctaa
    22981 tccaactaaa gttcctgctg tatcaaagaa agtcacaagc aagaatgtca gcactacgac
    23041 ccacatttga agagaattga tgtcccctac atgttttaat gcaactaaaa atgttggttt
    23101 caaacttggt gctgcggcaa caatttcaga aggcattgga atcaaacctg tgaccagacc
    23161 taaaatcgtt gtagctgcca tcccgatgaa gatgccacct ggtacacgcc gaacaagcaa
    23221 gatagcagtt acgactaatc caaaaatcgt caaccaagta gaaccaacgt tgagtgatcc
    23281 taatcctact aatgtagatt cattcgaaac gatgatccca ccttcgctca gaccaaggaa
    23341 agcgataaat agaccgatac cgccagaaat cgcatatttc aaatctgctg ggatcgcatc
    23401 aatgatcatt tcccgcagct tgaagattgt gatcaaaata aaaatcaaag aagcaacgaa
    23461 tacgccggct aatgctgttt cccatggaat ccccattcct aaacaaacag aataagcaaa
    23521 aaaagcattg atcccaagag caggtgccgt tccaattgga taacgggcta atacccccat
    23581 taaaacacag ccgatcgcac tggctaatgc agtcgcagta aacactgctc cttcatccat
    23641 tccagaagca cctaatacag ttggatttac aaataagata taagccattg agataaatgt
    23701 tgtaaatcct gccagtacct cacgttttac cgtggtgttc aatttttcta tttcgaagta
    23761 ggaaagtatt ttttccttca tcttccatcc ccctaaatcc gaacattata aataaagtcc
    23821 gttaaaattt cgatttatta ataaaacaac gtgttttatc atatactaaa acaaaacata
    23881 agtaaacaaa aaattcggat tttaagcaaa atccgaacgt tccatctgat taaatccctt
    23941 tatctcaaag ttcatgaaca ttcactttgg attacaagaa tttctttatt gtgttaataa
    24001 agtttcttca ttctagtctc aaaaatcaat agtgtgattt gattttacca tttcgtttct
    24061 gttcttcttt gatgaattct tttgtatcga caggattcag attatttagt ccgccaaaac
    24121 ctgtatcgac catttttccc cagccttttg tcttcttttt tcctgatttg agattctttg
    24181 ctcgaagctt ctcactatgt tttgctcgcc gatacttcaa ataaccttct aatcttccca
    24241 ttagatccac tgtttttcct cctttttatt caatcagacg actcagcttt tcctataaca
    24301 aaataattgc cttcagggtc agaaaaattg aaagtcaaga tgccattgtt atctgtgatt
    24361 tctcctggtt cttccatgtt ctcgtagata gtttcaaatt catccgtaaa aaatactaaa
    24421 gaaggcggtg gtcctaatac ctctggtgaa aacttctgca caaatacttt tgggaatacg
    24481 cctaattcta attcttttga gatgctgagt acaatactct taaattcttc tggcaattcg
    24541 attgtttcag aaatttctgc accaattttt tctacaaaga atcggcaaat catctctacg
    24601 tcattgacat aaagcatcac acgtgttttt tgtatcatca tttgaccctt ctttctattt
    24661 gattttcttt cctgtctata aactgattcc attatatcac gaaagcgcaa acaccttgtg
    24721 tttgatacta ttcaagaaaa ataaagcaat agtttctagg attgctttcc tccacaaact
    24781 ttttttacaa aaaaaaaacg gcaatgaatg ccgctcttct tatttcgatt cttttataat
    24841 tctgcttctg attcatcttt ggttagtgtg tgtctaacac tagttacgcc aaatgtttga
    24901 tcgatttttt ccttcaacgc ttcgattgcc tgtgcgccac gtgccgcttg ttcagcattg
    24961 atggattcaa tgaccagcac cgctgcttgt gtttcttccg tcagcatcgt tctttgggct
    25021 tcacgccagt tgagacagcg acagatcgct ccttgttcat catagtagat gatttcttcc
    25081 ggaagtgccg gagcatcgga atctgcacct aaaggcagga atgattcgcc accttgggct
    25141 tttcctaaat gcagatttcc tgcgatcttt tcgatatctt ctccgccgca aggtacgcca
    25201 aaagacaagg aaatactatt atagatatct acaagcggat tgattgggaa aaattcccgt
    25261 tcttgatttg cacgtttcag taaagcttca atagaagaac gtgcaccttt tttagtcttg
    25321 aatgtggtaa atgcctgacg ccactgagca atgacttcgt tttggctgaa tgtttcttct
    25381 gtaaggtaat ttcttgcttc ttttgctgcc tcattcaata attgatgata cgtttcttca
    25441 ctttcttttg ttacgtggtt atcgatacca tttacggata agatttcgat ggttgcttca
    25501 ggaaatactt cccagaaatt ggtatccact attacttttt tcatctgttc acacctcttg
    25561 attagaataa ttgcttgatg aatagatagt ctgtttgggg atcatctccc atataaaaaa
    25621 catgttcgct gtatttgata aatccttttt tacgataaaa agcgagcgca acatcgttgt
    25681 gttcccaaac accgagccaa atggctgttt tttgcttttc ttttgctttt tcaatagctg
    25741 tatctagtaa aaatgtaccg ataccttgat gtttaaattt ttttcgtaca tagattcgct
    25801 cgatttctaa aaaatgatca gccatttcct cagattgact cgttcctgta tttagtttca
    25861 ggtaacccgc aggctcttga tcgatactca ctaggaaaaa atcggtttct ttatctttta
    25921 gctcttctgt aagtttttct agtgcataag cttgtgtcaa gtaatcagct aaatgctccg
    25981 gtgaattatc ttttccaaat gtatctgtaa atgtttcgat actaatttgt tgtagtaagt
    26041 ctacatctga aggcgtcatt tttcgaattt cgtatttatt cacggcttct tcctttcaat
    26101 agatcctttt attgcctttt ttgacaaaat tccaatcttc gctaacattc ttgcatactt
    26161 tatttaaaag atattccaat tgttttgctt cttcgtcaga aagaccattt aatgcgactg
    26221 cattggagta gttgttttct cgaatgatga aaggatagat ttctgctcct tttttagtcg
    26281 gatagagttt cttgattttt ttattttctt tatcttccaa acgttcgatc atcccattgg
    26341 attctaattt cttgattgct cgggcagtcg ttgtacgatc tactttgatc atttctgcta
    26401 gtttttcttg gatgattcca ggattttcgc aaatacgtac taaataaaga tactgtcctc
    26461 ttgttaaatc gacttctttg aattcgatat tgctaataga atctagcgct cgggcaatca
    26521 ttccgatgtc tcgaaggatt tcagccattt catcccacct ttattttgtt tgtaagacta
    26581 gttcacctct ttttgttgca aatgcaacta ttttcaataa aaaaatcaag ttctttttta
    26641 ataactagta aagtatattc ttttcttctt ttacgaaaaa gctcaatcac aatagatctg
    26701 gtttttgttt tctaaaataa gtaactgttt cttcgttgtt cgcttttctg atagctttgg
    26761 caactcttct atactaaaaa atcccatgtt ggaagtttca ttattctcaa taaacttggc
    26821 ctcttcaccg tggatcgcac aagcaaaaac aagtttataa tactgaaaaa gctgtggaat
    26881 atctttttgt ttattcgtat caaaaactgc tcgcaactga gtagtttcta ctgttaatcc
    26941 tgtttcttca tagacttctt tacgcacatt ttcttcagga gacaatccta tttcagcaaa
    27001 tccaccagga agtgaccatt ctttcgtccg tttatcttcg attagtagga ccttgccatc
    27061 ttttttgata taggcacgaa catctacttt tggtgttgga tgtccttctc caatcgttgt
    27121 gagcgctttt atttcttcga aagtttcttt tcctatttca ctgatcagtt ccaatgaaat
    27181 cgtccggatc tcctcaaaac gctctttatc aaatacatct tttccataat atagaccagc
    27241 ttgagaaagt gcgagtagtc ttttgtattg agccaacttc ttgttcattc tcttcccttc
    27301 ttttttagca aatgtatgac tatgtaatca agtatagaag actggtttaa ttacggcaaa
    27361 taaatataat gaaatctgca ataaataaaa gaatgttaaa aaactcgaga acaaaagaca
    27421 ttcgacttct ctggggctgt gaataaatgg cgttcaaaag cttgcatctg cggtaataag
    27481 ccccaccaaa cgaaaaatat gacgagctat tcttgtctgg ctgttcttat taattgaggc
    27541 aggacagctt tttcacaacc tccccactaa acggtgttct cctaccaact cctcggtcac
    27601 aagtcacaat attcatcaaa catgagaagc tgtttttttg aaattgctcc ttgtgactcg
    27661 gagctgaacg acaggctcac gacctctcgg taaacagcgt tcaaaagcca atttttcgat
    27721 attaagccat ttctttgtta cttattgtca ttgatttctt tttctaattt atccaatagt
    27781 ggagtgtaat ccacttgagt atagtctgtt acatcaaatt catatagtgt tcctaactgg
    27841 aatttgtcat attttcggtc ggcgatgatc tttttgaatg cttctttcgt aatatgattg
    27901 gtccctttcg ttcgatcttc caatacgtca ccatagtgat aatgatccat gatatagctc
    27961 aaatgacgat ctgattcacg atcacgtttg taccgacgtt gccataacac ttcaaagtct
    28021 gctgttaggc gaatcgtgat cacctgatat ccgtatctat ctgctaattc ttggagtcgt
    28081 gctttttgct tatcactaaa aggatactcg gacacaatca ctttctttcc tgcttccata
    28141 tacaaatcaa gtgctttgta atagaaagga taaactttcg tcctttcttg ttccgcccgt
    28201 tcttccaaat tgttaaaccc gatggattct gcatagtatt ccttgatttc atcgagcgtg
    28261 atggcataca tatctggaaa tcgttcccgt agtttattca taagatatgt ttttcctgta
    28321 ccaggactac cagccagaag aatgaaatac tttttcatct catttatttc ctaagttaat
    28381 tggactttcc aagttcataa acagtccaat cttatgcttg acaatttctt ttactgcttc
    28441 atttgctgga atcacattat ggcgaagaga cttgttgatt tctgtttcac taaaggtttc
    28501 tttagctact ttcgtccagt tgactaaaag ctccgttcca acattgaatt tgcggatccc
    28561 gttattgatc aattcaggat aatcttcttc tttcacacct gttcctccat ggataactag
    28621 ggggacatca actactgcat cgatttcttt cagcaaggga atgtttactt ctgtttttga
    28681 tttgaattgt ccatgattcg taccgatagc aatagctaat gcatccacgc ctgtagcttc
    28741 tacaaatttc actgcgtctt ccggtcttgt atataccttg tcattttcag cgacatggat
    28801 tccttcttct gtaccgccga ttgttccaag ttctccttct acggaaacac cgtgcgcatg
    28861 ggcatattct actactgctt ttgtcttcag gatattttct ttgaaaggca gatgggaccc
    28921 atcatacatg acagaagtat atccgctgtc gattgcttct ttgatatcat caaagtctcg
    28981 ggcgtggtct aagtgcaaga ctgcatcaac catttcttct tctgcaatag ctgtcattac
    29041 attgactaac acatgcatgc cgatatattt agcggtatcg acacttgttt gaataatgat
    29101 cggcgaaccc atttcttttg ctgcgcctag catagcagga agcatttcta ggttatgcgt
    29161 attaaaagct ccaactgtaa aattcaactc ttctgctgtt tttgttactt ctttcaatgt
    29221 tgtatacatc ttttattgcc accttatctt tttatttgtt tcctttgatc gttacttgtt
    29281 ttgcaatttg tcgcatctca tccattttgc ccatgtagta atcgatccct tgatcatcac
    29341 cagcacgagc agcatctgca cgcttctggt tatagaggct catcagtttt ttatacccat
    29401 ctccgatcgt ctgtttattt tccaaactct tttctaaata ttggatggct tgatcgttca
    29461 catacaattc agaaaattta agtccaactt gttcataaag tttcgctaat ttatgcttat
    29521 cttgggtagt ggaaatctct tgtttcaatt gtgtaatctc tgattgaatc ttttcggtcg
    29581 cttctggcga tagggctttt tcttcttttg ccagaacttt tttcggttct ttttcttttt
    29641 tcttaaaaaa tccaaacatc attttcccta ctttcaatta aaatgctttc aaaactgggc
    29701 ttaagatcca ggcatataag agtgctgcgg ctactgtatc tacatcggtt gctgtagcat
    29761 tgttgaatcc catcgaatta aagatcgtta ctagcaaagc gggcaataat gtaataaaga
    29821 aaccatgagc aataccgcca atgatcgctc ctcggcgtcc gccaactgcg ttgccaaata
    29881 tccctgctgt ccctccggca aagaaattgg ttagcatacc aggtaaaatc atcgctaagc
    29941 cgaacatggg caaagtaaac atggcaataa tcgtaccaat cgttgtcgta atgaaaccta
    30001 aaatgacagc atttgggcta taaggaaaga aaactggaca atctaaggca gggatcgcat
    30061 caggaactaa tttcatagct atccctcgaa atgccggcac gatttcacct aacagtagac
    30121 gtacaccagc tagcaataca tacacaccca ctacgaattg gatggcttgt aaaaaggcaa
    30181 acatgatata gttttgatct cctgataatt cagaagcgaa tggttcgcct gcaaataaaa
    30241 cagtgatgat atatagcggg accatcacga ccatgacaga caaataagta tcttgcagaa
    30301 attcgaaatg tgtcggcaac ttgatatctt cgatcgactt tttattttcg cctttctcac
    30361 caaaaagctt agcaacaccg gcttcaaata agtacccgat cgtacaaaaa tgacctaaag
    30421 caatatcatt tgatccagtg attttacgaa tgatcggttg cgctactgcc ggcatagcaa
    30481 tggcgaaaca agctccgata aaaccaccga ccaagatcaa tacgatccct cgcagaccgg
    30541 caaaatagcc aaagactgtc gtcatcgttg ccatccataa aattgcttga ccagttaaaa
    30601 aaatgtactt ccattttgtg aaacgagcca aaataatatt gaatacaaaa atggctaaga
    30661 acgtcagtgc aatatctcta cctaaaccca aatcattcat tgcttgacca ttgatagatt
    30721 caatagaagg gatgatccct tgcatatgaa atccttcagt aaagattttc ccgaaataag
    30781 ttaaacttcc aacgatgatg ctcgaaccgg cactcaacac ttgaaatcct aggagtgtct
    30841 ttaacgtgcc agagatgact tgtcctgctg atttcttctg cagtagtaga cccaacatag
    30901 caatcaatgc aatggtgatc gatgcctgag tcaaaatatt ttcgatgata aaattgataa
    30961 cgcccatgtt tttaccctct tttctttttg tatttagata actcccttat cttgcagaac
    31021 tggggtgatt ttttcttcaa tttcattttt tgaaacaata tttttcaaat agatcatcgc
    31081 cgttttagga tcaactgcga acttttcgaa ctgcgaacga aaattttctg ctgtgatgat
    31141 cacatctggt ttcatggaaa ctgcggaaga aatatcacaa tggtccagtt tggcttctac
    31201 tcctaatttg ttcaaaacat cctcagcaga catctgtgct gcaaaactac ttcctaaacc
    31261 tgcaccgcat acgaataaaa tgttcaattt gttcatcttt gttctccccc gtatcattta
    31321 ttatttctca actactgaaa aaagcagttg tttgaaatct tcgatatttg tgcattcaat
    31381 caatcgatcc aacttctctt cgttgttgat caattcaatt agttctttca tgatgttcag
    31441 atgcgagtag gagtctactg ctgccaaaca aaaaataatc tttactggat ccatttcagg
    31501 attaccgaaa tcgattggtt gctcaatcgt agctacgctg actcctaatt tattgacccc
    31561 atcttctggt cgggcatggg ctagtgccat gtgtttgcca atcacgatat acggtccgta
    31621 atcattcact gcacgaatca tcgcttcgac atagcgctct tcgacaatgt tttctttaac
    31681 caatggtcta gcagctagtt caatcgattc ctcccaagta gtggcttttt ctttgatcat
    31741 gatattgctg tccgtcaaaa tatcttttaa cataggctgg atctcccttt tgttgatttc
    31801 taaattgttt gtttcgaata atttttctaa cttgccatag atgattcgat ctactcggcc
    31861 accactttct ttcatgacat ctattatttg agtgaataac tccgtcgatt catgactgtt
    31921 aggctctaac cgctgtagtt cttcatttct tttcaaaaag tcttctataa ccaagatatt
    31981 cgtctcagtt aaaatcggat cgacaactaa aagcggctta tttcgataat tcaattgaaa
    32041 ggtgctgaaa accagattga catccaattt atctactaat tcgatttctt ttgaacttaa
    32101 aactgcagta atctcgatct gaggaaactt ttctttcaga ttctctgcta acagatttcc
    32161 agtagccatc ccatggttac agacaacgac tgatttataa acataattca agtctcgctt
    32221 gattacactg gcgatcgtcg aaaagtggat gacaagaaaa gctatctcgt cctccagtat
    32281 cttgccacca attacttctt cgatcgtagg aacaaaatga gtgactgcgc ggtagattgg
    32341 gaaataattt gttcggatgt tttctttcaa tggattcatg acttggatat gattcttgat
    32401 tcttacaatc agtgcagcca tgtgcttata gagattttcg aataaagctt cttcctttag
    32461 atggaaaggt acgtgtgtct cgttctctac aaattggatc aattggatcg ttagtaattg
    32521 agcttgtacc cactcgattg aattggagat atctctagca ttgaacgtct caatagtgaa
    32581 acgaagataa tttctttcta cttgcgggac attgtccaat tgaaattcct cgatcatgtg
    32641 gtcaataaat gcagaaaagc tactgtcttt tatttctgta tttttccaat taatggcaga
    32701 gataaattca tgtttcctga ttcgctggat ccagatcaat gtaaaaagca ggatttgttt
    32761 tttataaata tcatcttctt gtttcaacaa cttattggaa tagatctcct gtattttttt
    32821 gatttccacc aaaggaaaat aatggagaaa gattttttga gccggtgtta attgtgcatc
    32881 ttgattcata aagaagtcgg tcattcccag attctgattg ataaaatcat agatcatcgt
    32941 acggatagat cgttctgaac ctttataaac cagtccttgc tttccataac tgacgatctc
    33001 tatcccataa ctgaccagtg ttgctcgtaa ccgtctcata tcttcatcta atgtactttt
    33061 agagatttga aattcttctt cttttttgtt tagatggatc gggattcggc tgtaagcaac
    33121 ggctaaaact agatcaaaaa tacgttcgcg ccgattcaaa aagccgtctt tcacatcttt
    33181 tatttcagtt tctaatcgag cttgcttttc cttttccagc ttcaacaaaa aacctttgtt
    33241 gcgaattgta cggatctccg gaagcttttt actgctcaac cagatattcg cttcaagaac
    33301 ttcctgacgg atcgtccgct gactgacatt gaactcactt gctagatgtt ttgcttttac
    33361 tggatattgg gctgtcatga ttctgtgaag tatttcaatt gttcttgttt tcatagaaat
    33421 gatctccttc tgatttcaag tatatggttc cgcttacata ataaaaagta gatatttctg
    33481 ccacttgaag tggaaagaaa gtaagcaaag caaacaaaaa ataagccata tgctttttca
    33541 tctcctcaac gaaaaagaca tacgcctatt attacaaaaa ttttgcccat ctatacaaaa
    33601 aagaggttgt gaaaaagctg tcctgcatca agtaataaga acaactaaac taaaatagtg
    33661 cttcctattt ttcgtttggt tgttcttatt atcgcagatg caagctttta aacaccattt
    33721 agtggagagg ttgtgacaga gatgttcagc cttgagcgat aagaagcgat tttgaaaaat
    33781 cgcttcccat attttacaaa atcgtgcctt attgccgata ggctatctct ggcacaccgt
    33841 ttattcagaa aaaggagctg cgacaaggct tttgtcacaa ctccgttcat aaatatttcc
    33901 tgtcaatcca gcataatcgg ctgaataaaa tcggcttgcc atcttttttc tttctcagaa
    33961 aaatcaaaat accatatctg agaaaaatac tgtcgttgtg tcttacttcc tgagatcaat
    34021 cgcccatctt ttcgatcgac tgaataatca cagcatctga aatcaattcg gatggcaaaa
    34081 ctattttcgt ggatctgtcg ataatttcct acttcctgaa tagttatttt tttagtatga
    34141 tttcttacac cgtctgcttt gtttttttgc agaactttct gatgttcggc aaacagcttg
    34201 tctgtataac agcttctggc tttttcagga gtttcttctt cccaagcgga ttggatcttc
    34261 atgaatatct tttggatttc cagaaactgt gctttctttt ctttagccgt tcctgacatg
    34321 cgggacaata tctccgcttt cagccttttc ttttgtcttt tattcttgac gatagaaaaa
    34381 gcagaaaccc ctcctactga caaaacagct aatgcaagaa atcccgtttg ctcataacta
    34441 gaaggacctg tacctggacc ataataccca taagaatctc tgccgtaaga acgactgcca
    34501 aaataactgc ccccatatga acgaccacca aatgaacctc tgcccgaact tcgaccgcta
    34561 gatgtacctc caccatgacc acccgcgaca gcgaatcctt gggtcggcag agcaaacaaa
    34621 cataggccca ctaacaaaat gattgctaaa taattgattt ttttcattgt cttcctcgtt
    34681 atcttttatt acaaaaaact atttttatga tagccttgct aaaaggaaga gtcaataacc
    34741 agatgcataa actgtttttt tagcaatttt gtcttattta gtcattgagt aacatcggac
    34801 aaatgtatgt gtcggcagtc cataattcct ctatcttcag catgaacaag cttgcagaca
    34861 agagatctgc gcttcctcca ggagagattt ggttttcctg acaaaagtgc aacagtgctg
    34921 taaatggacg atttggtaaa gcactttgac tagcagcatg agcaagtttt tgcatttcca
    34981 ctaacgtttt ctgatcactg cgatgcaata cgcatgtgtc atctagcgaa ctcatcaaaa
    35041 ctaacaacat atgcatttgt ttctgtacat atgaatcatt atctagctcc ttagctgctt
    35101 gaattgcaag cctgatatgc ggatacccta atatcgcttc ttcatatgca ccatttacgc
    35161 catatttttg cttcacccta tgaccatgag tggttttttt atgacgatat tttgtatcag
    35221 gaaaagcagc aagcttgctg acatcatcaa gtattttcga taaagaaaaa ggctgttcca
    35281 tactgatttt ttgtgcaatg acactgatca atagccccat tgcccaaatc gctcctttat
    35341 gggtattgat gccatttgta gcaatcagca ttgccttttc cgcttttcgc ccaatctcag
    35401 caattctttc tcttaactcc tgatcaatag catgatgcca tgctatttga gccatttctt
    35461 caaaaaaagg agttagcgtc ttagcagact taagaaataa agcatagtcc atatcggaat
    35521 gtgcacccgc atccagtgca tccactaatc caggttttgg acttaatgtt acttctgcga
    35581 tcaatgcttc ctctaccaac gcagcgagtt gctgagtcac tgcttttttt cgttcgtcat
    35641 ttatcatgac actcactcct tcttcctact attacttgct gaaacctttt ttgatagcta
    35701 cccaaatgat atgaagtaac cagcttaaag caaatgcaca acttgccgtc attagataag
    35761 ctacaagaat catgactcct gaaggtaact gcagccaact atctttaaac aataataaca
    35821 gtacttggaa aacaaataca ttggctaaat acgtacgata agcataaaca gacaaccatt
    35881 tgaacaatgg caattttggc gaatcgttta caatcatttt ggaagcgcct atgaagacag
    35941 caaagatgat gactaaactg tataaacttt ggatcgtatt caagtaaggt gcattcgcaa
    36001 agctcaagtc tcctggatgt gcgagcaatg aacggacaga aaagaacgcg ataactaagg
    36061 caacaggtaa gaaaagataa cgtactctgt ccaaatattg atagactttt tcgtgataaa
    36121 caaatgcggc taccccataa atcatgaaac tagcaacaaa ccgatctaat aagtaccagc
    36181 tgtcatgata aggcccagtc aatacttgtg tttgatagaa cagataccat gcgacatata
    36241 aaatcgttga accaatcaat actggccata catatttttt attagcaaat actttgtaac
    36301 cgagccaaac aaaaaacggc atgaacaatt ggatctgcag catcataacg gtataccata
    36361 aatgaggcgc tccatcacct gtgacatatt tcagtaaaaa gcttgcagta tccgtatacg
    36421 gagtttgttg ttggactgct ggaaatagcc aaagataagc cgtcgtccat agaagatacg
    36481 gaacgactag ttcaaaaaac ttttctttca aaaattccca ataagacaaa tgctgacttg
    36541 tttttaccat attataaaca attgcaaaaa taaacattgg tgctgtgtat ttaacgatga
    36601 cgtaaaaggt accaagaaaa gctgtatttg ttgcgctgtg gctgtttgcc aaagcaaagc
    36661 tcaatatcgt ttgcatcata acagccgtta cagctgatac tttctggaag tcacttacgt
    36721 tgattttgat ttttttgttt tcaaacatct ctttctctct ctttttcttt attaccaaag
    36781 ttctttggtt aatttaggtc cttcgactgt tttcaataga atttttttct ctggctctct
    36841 caaatactct tttagtgaaa aaccgccttg ccgagtcact acttgggtat cgaattgctc
    36901 aaaaaaagca ggatgcgatt gaattacctg aattggcaat tcaatcggtg aatttgcgta
    36961 cagcagcaaa tcaaaatcac tggtttcttt tactgccgga atcccagtcg ataattcaaa
    37021 tcctaagctg ccgccgattc cccatttaca tcctgataat atgtttctag cagcatgaaa
    37081 ttgctgataa acaggataat ccatgatttt ctcttgtcta tacgattctt gttcgatgat
    37141 gtcccacgga tgaatgactt gtttgacggc atgttttgag atttctgttg accatctctg
    37201 attgcgggca ggtccacgta aaccaatcgg tagtatttct gcgtgatccg tcgacgcacg
    37261 acgaactgtt ccgaacatct tttcagttag aacgacccat tcaggcaagg tgaacccttc
    37321 tatttcatgt ttatcaaaaa ggacaatatc atgtgcttga atcatttttt atgcatccca
    37381 ttcttcgtcc attttggcac ggactttatt tgtttcgaca cgtccgaatg ttttggctgt
    37441 ttcgtttgtg tatcgatttg tcagcatcgt gtcatttgta ttgcggacat cttgaatggc
    37501 ttcattgatt gcttcgatga ctttgctgac attttgttct gaagcagctt ggtcggtgat
    37561 atcttctagg aaatgataga tcgctcctag ttttgtataa ttattgatat cgtaagcgat
    37621 agctggaact ttttcagcag ctgcttcgat ttcagcaacc gaacgttttg tcacacgtgc
    37681 agcactttct ttagacatcg cttggacggt aatttcttta ttgtttaaag caatcaagcg
    37741 gcttgattgt aatccatgtg ctaaaaatgc acctgaaata gcatttcctg caatcaatcc
    37801 aataactgga tgtccagctt gacggagttt tgcataagca gcagcactat tagccaaagc
    37861 cacatggata ccgatcaatt cttcgttata gccgtatgct tggcttggta catcgatcac
    37921 aacgatgatt ggccgtttca cttttttgtc tttatcttct tcgtaaacgt gatccaaaat
    37981 ttgtcccatg cggaaacctt caactaaacc aacttcaccg tttcgtacac ggtacatcgg
    38041 gtttttagga tcaggtacga ttgatgtcac gatggcttct tctatgaatt tacttgattt
    38101 accataatac acagtactaa tagaagaagt tggatttttc atgccagtta gtgccgcaaa
    38161 ccaatcgtaa ccaacacttg ctgcagctgg ttcatttcct tctgctactt ctggtaagtc
    38221 aattgatttt gcttgatggt tagcaattgc ttcattgtaa tcgtcaatgg ccattggttt
    38281 tgaaagatct aaagaatcaa gtaatgataa ataaaatgct gagctttcac tgcgatgcgt
    38341 gtcttttcgt tcgtccattg ctgcgatgac agcagctttg attgcttcta cactatcagt
    38401 cactaattca tcaatgattt ttgattctac ccgttgacga gatcctaatg tattccaaat
    38461 caagtctttg tcactagaat caaattctcg aacgcctgct tcttgttcaa taacttctgg
    38521 tccattcaaa ccgactctcg ctttttttgt tgcgattaaa taactcatta atgctgaagt
    38581 aatcgacata ccgccaaatg atcctacacg tcctggaatc aaaccgatga ctggtacata
    38641 ttgttttaga gcaatgatta catttccgat ttctgaaata gataacagtc cgtagtttgc
    38701 ttcttgcaaa cgaacaccac ctgtatctag tacaatgact ggaaagatct catttccttt
    38761 tttattttct tctaacacat gttcaagtgc agcaacgatt tttgcaccgg aaacttcacc
    38821 gataccgcca ccttggaatt ttccttccat agcgattact actgcttgtt tgccattgat
    38881 cgtgccacgg ctgacaacga tcccgtcatc actttcaggg acgattcctt gtgctggtaa
    38941 acttggcgcg atgatttgat cgaatggatc aatcaattca cgtccattgt caagtagagc
    39001 gttcactcgt tctctggcgt ttaattctac aaaactattt ttcatctgaa agttcctcca
    39061 ttgcttgcgt caatcgtagg tacacaactc ctggtgtagc accgaagtca ttgatcacga
    39121 tatctgctga aattggataa cgatcaaaaa atctcgttaa tacattgttc catacttcgc
    39181 cgaagccatc gcttcctgta caaattttta cagtagattc tgttttttct gttggaaaca
    39241 tcaagatttc caaatctcct gaaccgacca ctcctacatg gattttctta ttgatcggct
    39301 gtttcgttgg atatttataa gctaattgtt ccatggatct ctcccctttt tgtaaaacag
    39361 agcatacacg ttctgcttat tcgtctttct tcttccatct gggtaaatgg cgacaaaagg
    39421 tttttctcgc caattttatg accaagttct gaatttcatt ggtggttcat acaggccatc
    39481 tgaccattcg atcaaatcat cgatggtttg tgcagctaat aatgaacgtt tcgcttcact
    39541 acgtttgatg cctagatctt ctggtaattt cacgatgccg gctgcacgca agctatctag
    39601 tgattctttc gtgctagtca ttccaagagg tgtaacaccg ccaattgctg caattgctgc
    39661 ttgtcgttct tcttttgttt ttgctttgta caaataagca attccttctt ctgtcacgat
    39721 atgtgtagta tcttcgctat aaatcatcac tggtgcattg gctaagcctg cttgtttttg
    39781 aacagctagt gcatctaatt cttcgacaaa gactggtttt ttatttgaac catatgtttc
    39841 aaccatttga acaactaatt tttggccttt ccctaatgga tcatcattgt cgcgaagtga
    39901 ttgccatgct ggtgtagaat gacgacgacc gccaggatta tgtcccatgt taggcgcacc
    39961 gccaaaacca gataaacgtc cttttgttac ggtagaagag tttccttcgt aatctaattg
    40021 caaggttgaa ccgataaaca tatcgatggc atattgtcct gcagcttgtg ataatgttcg
    40081 gttactgcgc atcgtgccgt ctttaccgac aaaaaagaca tctgggcgag cagcaatata
    40141 tttttccata ccaacttcgc caccaaaact atggatgctt tcaacccaac ctgattcgat
    40201 ggctggaatc atcgttggat gtgggttcaa tacccagttc ttcgcgattt tcccttttaa
    40261 ccctagtgat tcaccataag ttggcagtaa caattcgata gctgctgtat tgaatccaat
    40321 accgtgattc aaagattgta cgccgtgttc tgcgtagatt cctttgattg ccatcattgc
    40381 cattagaatt tgcaattctg tgatgttttg aggatctcgt gtgaataaag cttctaattg
    40441 ataaggttta tctgctttca cgacaacgtc tacccagtca ccagggatat ctacacgtgg
    40501 taaagaatcg acaacttcgt taacttgaac gatcacgata ccatctttga aagctgcagc
    40561 ttcgatgatt gttggtgttt cttccgtatt gaaacctgtg tacaagttgc cgtctttatc
    40621 tgctttatct gcagctacta aaacaacatt tggaatcaaa tcgatgaata agcgtccata
    40681 aagttccaaa taagtatgga tatcacctaa tttcattgtg ccgtcttcaa tcatttgggc
    40741 gacacgcaag ctttgtgcac cagcataaga gaaatcgatc ttgcttgcga ttcctttttc
    40801 aaaaatattc aaatgttctg gtcgtgagat actagacatg atcaaatgca gatcattcac
    40861 tttttctgca tctacttttt caagactttc tgaaagaaaa cttgcttgtt tttgattgtc
    40921 gccttctaat acaactttgt cgccgggagc aatcagtttt tccattactt ctacgatttt
    40981 ttcagtttct acatacttgc cattgagcaa gttgctgatt ttttccaatc gctgcgcttt
    41041 tttttcgcgt ttagaagccc agttgcggtt tggtttttcc ataattagtc atctccattt
    41101 ttgatataga aacgtggcgt catcaatacc atgttggtct agattgatcg tacggatccc
    41161 tttatctaca ccaaattttg tatgaatcag ctttgtcaaa gtattgccgg ggggaaattc
    41221 aatcgtcaga tccattccta attcttttgc caagtccatc atttggttcc actgcacagg
    41281 gaaagctagg ttttccaaca aatctttacg aatctcttct gcgtcctgag tggctcttcc
    41341 atccgtattt tttatataca aacatctagc atcagataga tggacagact gcatatacgg
    41401 cttgaatttc ttgaccgtat cattcatcaa gagacagtga gatggcacag ggactttcag
    41461 cagcttcgct gtttgcgctt ggtgccgttt ggcttctgcc aacgtaacgg ataaaccttc
    41521 gatactccca gataacgtat gttgcatcgg acaattttca tttgacagat aaactggatg
    41581 gtcaggatca aatgtttttg ctacaatttc ctcagcttcg cttctcgtca cacctactac
    41641 tacgcccatt gcataaccgc ttggataagc ttctttcatt aagactgcgc ggtgatagac
    41701 tagttccgct gcattctcaa atctcaaaga tcgacaagca acagctgcac aaaaagcacc
    41761 aatcgaatgt cctgctgcaa tatcaggctg aataccgttt ttttccattt catctaaata
    41821 aaatactgct tttgtcagta atgctagctg gataaaaacc gtatcttgat agttttcttc
    41881 tttatcaact aaccgatacc ccgtcacatt ttctaaacgt tccatgtaca tttcagggat
    41941 atccgctaac atccctaact tctgactgcc ttgtccagga aataagaaac ctgtactcat
    42001 gagcctcgcc tcctcagcac ttactttttc cactgctatc ttagtcaatt tctgctataa
    42061 taaaaaatgc caaaaaaaga aaaaaccata acaaaaaggt atggatggga tggataatta
    42121 tgaaattgct tcatctgcag tattttaaaa aagtattcga aacaaaaaat gttacccaag
    42181 cagccaaaga attatttatt tctcaacctg ccttgagccg tgcgatcaaa catttggaaa
    42241 acgaattagg tgtccctttg ttttaccata gcggcagaaa cattgagacg accgtttatg
    42301 cagaagaatt ttatccatat gcagtcaaga cattagacac attagaagaa ggaatcaaat
    42361 tattgtcttc ggtcaatgag aagatcgtta cttccgtcat attgtattta gaggtagcct
    42421 ctgtttctat tccgaacttg gtccgaattt ttatggaaaa gcatcctgat atccaattaa
    42481 cgatcatgca acatcattta ccagatgata ttaccgatcc tgtactgtac atcacttcgg
    42541 agatgaagcc tggcatgacc aatattccta tcatgaaaga acctgtttat gtcgccattc
    42601 ctaagaaaca tcctcttgct aaaaaagaac atctgcaatt agaagatatc caacgcaccc
    42661 ccatcttgat gctgtcaaag agcaacgcct tccgtcatac actggatgca gcacttgaag
    42721 cgaaaagtat cgaattgacg atcagttcga cgacagatga tcctgcgaca ttacgttcta
    42781 ttgtcaagca aggattagct gttagctttt tcccaaaagt ttcttggtct tacgataaaa
    42841 atgatccttt cgtcttgcgg gaaatcaaag atttgccctt gacacgaaca atttatttat
    42901 cttctagctt cacagaagat catcctttga tcaaaatgat tgcaaaaacg atgcgggaat
    42961 tttatttagg aaaataaaaa aaaaagagct gggacaaaat tcttgtcgca gctctttttt
    43021 cgaacaaacg gtgttccaga agtaatttct tagaaaataa gccgaaattt cccaaaaatt
    43081 tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag ctaaacattt ctgtcacaac
    43141 ctcttctcta ttgtcctaga cattcattgc gttgatttaa aacttccatc aatcaaatct
    43201 gctagttcat ctagcttttc tattttacgt agatcaatag agatccaatg ttctttattc
    43261 atgtgatagg ctggaaaata cccctctttt cctcgcaaaa ttccgccaag ttcaggatcg
    43321 accttcaaat caagaatatt gatgatccta tggtcacttg catcatcata gattttttct
    43381 tctggaacag acatcaggac cccaaaccat tttttgcttt tttgatgtct gaatacgcaa
    43441 taatcaggaa attttttaaa aatatattct ggagacaaat tgtatgtttc attgatgtga
    43501 tcgattagtt cttttttcgt tagcatctgc ttccatctct ttcttattga ttcgctttat
    43561 tcaaagatac cacgtaagaa tagaaaaatg aatacaagta gttgctaatc aaatacttcg
    43621 atatttttct tttttatcaa ctcttaaatg ttcaatccgc ctgtgttggt cttgctacca
    43681 tctactatta aaatgtttat tattgtttgc ccacctattt tttgatttta gtggtatcat
    43741 ttttcaagtt catgatgaaa ttcttatcat cagtaaatgc tccagaaaaa taaacaatga
    43801 ttgaaaaatc agttgaaact tgaccaccgt ttattttctc cgtattctta gaatagaagg
    43861 gagtctgatt gatgtattca ctaatgaaaa aaatcattac cgaaaaagat attcgacgtc
    43921 atgtttcttt agtagaacaa ttgctgaatc atacaaagat aaccgtaaat gaattagctg
    43981 aaatcatagg gacaaccgaa cgaacgattt tttctgacct tcaatctatt cgctctcagc
    44041 tgcccgaagg ctgggacatc atcagcgatc aagcaggaat cagtttgcaa aaccagcaaa
    44101 atttattaac aaatgacctt tgggagattt ttttcaaaca atcagtcagt gtcgaactgc
    44161 tgaaaaatct gctttttaca aaaaaagttg ctgtccctga ttttctagcc gaccatgggc
    44221 tttcttatgg gacattgaaa agacatgtga ctaaaatcaa tcagcgttta gcaagttacg
    44281 acttgca
//
LOCUS       DADGHT010000010        41270 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.010, whole genome shotgun sequence.
ACCESSION   DADGHT010000010 DADGHT010000000
VERSION     DADGHT010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.010"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(143..1729)
                     /locus_tag="JX887_000487"
     CDS             complement(143..1729)
                     /locus_tag="JX887_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAX1256500.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            1980..2204
                     /locus_tag="JX887_000488"
     CDS             1980..2204
                     /locus_tag="JX887_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAX1256501.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            2346..4097
                     /locus_tag="JX887_000489"
     CDS             2346..4097
                     /locus_tag="JX887_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1256502.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            4097..5881
                     /locus_tag="JX887_000490"
     CDS             4097..5881
                     /locus_tag="JX887_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256503.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            6339..7190
                     /locus_tag="JX887_000491"
     CDS             6339..7190
                     /locus_tag="JX887_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1256504.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            7287..9173
                     /locus_tag="JX887_000492"
     CDS             7287..9173
                     /locus_tag="JX887_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1256505.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(9214..10116)
                     /locus_tag="JX887_000493"
     CDS             complement(9214..10116)
                     /locus_tag="JX887_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAX1256506.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            10346..11749
                     /locus_tag="JX887_000494"
     CDS             10346..11749
                     /locus_tag="JX887_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAX1256507.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            11749..13182
                     /gene="ascB"
                     /locus_tag="JX887_000495"
     CDS             11749..13182
                     /gene="ascB"
                     /locus_tag="JX887_000495"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAX1256508.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            13327..14253
                     /gene="trxB"
                     /locus_tag="JX887_000496"
     CDS             13327..14253
                     /gene="trxB"
                     /locus_tag="JX887_000496"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAX1256509.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            14466..16193
                     /locus_tag="JX887_000497"
     CDS             14466..16193
                     /locus_tag="JX887_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAX1256510.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            16266..16559
                     /locus_tag="JX887_000498"
     CDS             16266..16559
                     /locus_tag="JX887_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAX1256511.1"
                     /translation="MPDTQKTKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAIIQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(16643..17503)
                     /locus_tag="JX887_000499"
     CDS             complement(16643..17503)
                     /locus_tag="JX887_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAX1256512.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            17595..18023
                     /locus_tag="JX887_000500"
     CDS             17595..18023
                     /locus_tag="JX887_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAX1256513.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            18185..18361
                     /locus_tag="JX887_000501"
     CDS             18185..18361
                     /locus_tag="JX887_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAX1256514.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            18388..18834
                     /locus_tag="JX887_000502"
     CDS             18388..18834
                     /locus_tag="JX887_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAX1256515.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(18990..20369)
                     /gene="brnQ"
                     /locus_tag="JX887_000503"
     CDS             complement(18990..20369)
                     /gene="brnQ"
                     /locus_tag="JX887_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAX1256516.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            21075..22046
                     /locus_tag="JX887_000504"
     CDS             21075..22046
                     /locus_tag="JX887_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAX1256517.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            22070..24262
                     /locus_tag="JX887_000505"
     CDS             22070..24262
                     /locus_tag="JX887_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAX1256518.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            24279..24755
                     /gene="ybeY"
                     /locus_tag="JX887_000506"
     CDS             24279..24755
                     /gene="ybeY"
                     /locus_tag="JX887_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAX1256519.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            24733..25134
                     /locus_tag="JX887_000507"
     CDS             24733..25134
                     /locus_tag="JX887_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAX1256520.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            25149..26048
                     /locus_tag="JX887_000508"
     CDS             25149..26048
                     /locus_tag="JX887_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAX1256521.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            26191..27003
                     /gene="recO"
                     /locus_tag="JX887_000509"
     CDS             26191..27003
                     /gene="recO"
                     /locus_tag="JX887_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAX1256522.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            27387..28304
                     /gene="glyQ"
                     /locus_tag="JX887_000510"
     CDS             27387..28304
                     /gene="glyQ"
                     /locus_tag="JX887_000510"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAX1256523.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            28306..30381
                     /locus_tag="JX887_000511"
     CDS             28306..30381
                     /locus_tag="JX887_000511"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAX1256524.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRASRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            30771..31550
                     /locus_tag="JX887_000512"
     CDS             30771..31550
                     /locus_tag="JX887_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256525.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKNFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
     gene            31596..32540
                     /locus_tag="JX887_000513"
     CDS             31596..32540
                     /locus_tag="JX887_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1256526.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTLQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            32556..33335
                     /locus_tag="JX887_000514"
     CDS             32556..33335
                     /locus_tag="JX887_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAX1256527.1"
                     /translation="MEETISLKEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            33347..34045
                     /locus_tag="JX887_000515"
     CDS             33347..34045
                     /locus_tag="JX887_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAX1256528.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            34073..34837
                     /locus_tag="JX887_000516"
     CDS             34073..34837
                     /locus_tag="JX887_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAX1256529.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMTASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPDYEEVKKKKFGLF"
     gene            34851..36668
                     /locus_tag="JX887_000517"
     CDS             34851..36668
                     /locus_tag="JX887_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAX1256530.1"
                     /translation="MFILTRRRKIATLVFVDSLLLIAANIAAAKFMKPFVSIPMDLIL
                     ISIGLSIGFYLFYGSLFKVFTRINRYTNLREIIAIFSSLSASAASSILILLFINRRYS
                     LRLVIFAYLLSLLLIIGSRLIWRIYIETKNMRYVSADSAKNTLIVGAGEGGRILYNSF
                     LGSKTAQDIHVVGFVDDDPNKRNTYLSGKKVLGALKDIPELIEKYDIQMVTIAIPSLS
                     RKKLRRIFELVESARVKVNTMPSIEELASGKISVSKLKTIDVVDLLGRDEVKLDIESI
                     KDQITDKVILVTGAGGSIGSEICRQIIQFNPAKLLLLGHGENSIYLIDRELRTHHQNC
                     PTEIVPIIADIQDREKINEIMEQYHPDIVYHAAAHKHVPLMEYNPKEAVKNNIFGTKN
                     VAEAAKAAKVKNFVMVSTDKANNPPNVMGSTKRIAEMIVTGLNEEGCTKFSAVRFGNV
                     LGSRGSVIPVFREQIAQGGPITVTDFRMTRYFMTIPEASRLVIQSGALAKGGEIFILD
                     MSEPVKIVDLAKNMIRLSGYSEDEIEIIETGIRPGEKLYEELLLDKERNDEAVYEKIF
                     VGNIKGYSIQKVMDFVKSLPQDDEQLAKDIVTFANASNR"
     gene            36722..37645
                     /locus_tag="JX887_000518"
     CDS             36722..37645
                     /locus_tag="JX887_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HAX1256531.1"
                     /translation="MNAFKTALNNNEMEGKIIGADCSELAPALYMCDEKIVLPKVSES
                     NYIEELIKVIKFFEIKLIVPTIDTELSTLSRNKKYIENETDSVVLVSSEKVIDICENK
                     ILTSAFFEQNGFKTPEILNSSEITKFPVFIKPLNGSSSVNTFIVNNEKELLFFSEYID
                     NPLIQEYILGEEYTIDVCLNFDSTPVSIVPRKRIATRGGEILKGQIIKDRELIETTKK
                     MLEKLNAIGHITIQCIKNEKGIFYLEINARYGGGAPISIKSGANSPEYIIKMIDSKKN
                     LRYRENYLDKMIALRYDQAIYLDEKGNVYND"
     gene            37617..38333
                     /locus_tag="JX887_000519"
     CDS             37617..38333
                     /locus_tag="JX887_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAX1256532.1"
                     /translation="MKKEMYIMIKAVIFDLDDTLVSEYDYVKSGYKCVARRLAVQKIF
                     PATFDEIYRVLLDLFAEDSKNVFNRLYDYFEIPYSKKEIKELVNVYREHKPDINFLEN
                     ADTLLTELRSRGYKLGIITDGYAITQRNKLDALKVDYLVDYICITDELGRELWKPHPI
                     SYLLLLEKFNLKAQECIYIGDNELKDFITAKSIGMQTIKIERVNGIYRESSLKFKRFY
                     QADKKIRSLWEIKNFLGVIS"
     gene            38330..39448
                     /locus_tag="JX887_000520"
     CDS             38330..39448
                     /locus_tag="JX887_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAX1256533.1"
                     /translation="MKSKRILLASPHMSEEGYEKEYVKEAFDTNWVAPLGANVNGFEK
                     ELAEYVGASHAAALSSGTAAIHLALKAAGVGKDDIVICQSLTFSATANPILYQGAIPV
                     FVDSDYETWNMKPEHLRTALEKYPNTKAVLVVHLYGLSANLDEITKICKEYDVTLIED
                     AAESLGTTYKGKYTGTFGDYGIYSFNGNKIITTSGGGMLVSNDKEKVEKVRFWATQSR
                     EKARHYQHNEIGYNYRMSNIVAGIGRGQLKVLNERIEKKRYIHSFYKKELSKLSNIQF
                     MPENNWNEPNYWLSVITIKGINANHLIDELDKNNIEARPVWKPMHLQPVFKNYDYIGD
                     DVAETLFDLGVCLPSDTKMTDEDLKYVVSTIKRVINDA"
     gene            39441..40058
                     /locus_tag="JX887_000521"
     CDS             39441..40058
                     /locus_tag="JX887_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAX1256534.1"
                     /translation="MRKKTFYQLFGKRILDILLSGIALIVLSPIILIVGFLVRIKLGS
                     PIIFKQERPGKSEKIFSMYKFRTMTDERDHNGEYLPDEIRLTKFGKMLRATSLDELPE
                     LWNILKGDMSIVGPRPLLVEYLPLYSEKQRKRHNVRPGLTGLAQVNGRNAISWEEKFD
                     LDVYYVDKISFFNDLIIIIQTCKKVIKKENINTINNNIPEKFKGS"
     gene            40185..>41270
                     /locus_tag="JX887_000522"
     CDS             40185..>41270
                     /locus_tag="JX887_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAX1256535.1"
                     /translation="MCRVLNILFQYEKIIKKYKEKRVMAKYYNKKILIMANNDDGLYR
                     FRGMLIKNLVDQGNEVIVSLPKGKNIPKLIELGCQIIETPIDRRGINPKTDFKLFFNY
                     CNILKKIKPDMVIAYTIKPNIYGGLACRLRKVSYALNITGLGTAFQKKGVLKSLIVFL
                     YRLAAKKSKVIFFENFENMKTFQTLQIAKQSKYKLLNGAGVDVEHFSYLEYPKDEQVH
                     FLFIGRIMKEKGVDELFEAMKNLYSEEKNCVLDVLGYFEEDYGIKIEKYEKEGWLKYH
                     GYQSDIRPFVERAHCFVLPSWHEGMANTNLESAASGRPIITSDIPGCKEAVIESKSGY
                     LCERKNSCSLYNSMNKFLKLSYEQRINM"
BASE COUNT        13943 a         7107 c         8691 g        11529 t
ORIGIN      
        1 atacacggtg ttccagaagt aacttcttcg gaaataagcc gaaatttcac aaaaatttga
       61 aaagcaattt tcttaaattc cttcttattt cttgaagctg cccacttctg acacaacctc
      121 ctttgtgtaa aagaatcagt ttctactcga tttcttctat cgtttcctgc aaacgctgtt
      181 catatttttt gtttccttta tataaatcac caatcgtcca tgccaacagg agaaggacaa
      241 gaacaatgat tacataagcg atttgatcag ccaatgctag ttgagctgag gtggcttgct
      301 cgccgaagaa actttcgatt tgacctggta atcctcgtaa attcaagtaa gtcagactaa
      361 tcacagagaa ccagccaagt agttttacaa caaatgaatt tttgaatcgg ctccccatct
      421 ccgcttggct attggtcatc atcagtaaag gaatcatcga gaatggcaat gcaaaagcca
      481 gaaaaacttg ggattcattc atcaagttat tcaaagcggt atgttcttcg atcgttcctt
      541 ttgtacttgt aaacaaaaca caaatcaata caggaatcac agaaagcaat cgtgtgacta
      601 gtcttcttag ccaaattggg atacgcatat ggatgaagcc ttccatgatg acttgaccgg
      661 tcaacgtacc agtaatagta gagttctggc cagaagcaag aagtgctaca gcaaataaag
      721 tagacaagat accagatttt gctacagcaa tcaagatacc attgctcata gctgatggat
      781 cagataaagc ttcatacaga ccaaaaaagg aaggatcttg gacagaaccg gttttgaata
      841 cagccacacc catgatcaat agcagtgcat tgactagaaa agccattgac aactggatat
      901 tagaatccca agtagaaaag cgtaccgctt gtgctacatc ttcttcgtct tggtgatcga
      961 tcttccgagt ttgagaaact gctgaatgaa gatataagtt atgcggcatg actgttgcac
     1021 caataatccc taaagctcca gtcagcggag tttcgccgcc gatgaccggt gagtctgaga
     1081 atgtgtgact gttagggata aatccggcaa acaaactgtg ccaatcaggg ttagacaagc
     1141 caacttgata gacgaaaacg aataaaatga cgaaaatcaa gcagacaacc aaagcttcga
     1201 ttttacgaaa cccgactttt gtcagcaata aaaggacgaa aacatctaac acagtgataa
     1261 atacggcaat taccaatgga atatcaaaaa gcaggtagag ggcgattgct gcaccaatga
     1321 cttctgcgat gtctgttgcc ataatggcta attcagtcaa gatccataaa atgacaccca
     1381 atgtcttact tgtccgtgct cggattgctt gggccaaatc catttgggtc acgattccta
     1441 attttgctgc catatattgt aaaagcatag caatcagact agacatcaaa ataactgaca
     1501 tcaataaata ttggaaattt tgtccaccag tgatcgaagt ggaccagtta cctggatcca
     1561 tataaccaac tgctactaat gcacctggtc cagagtaagc aagaagtgtt ttaaaaaaac
     1621 tttttccctt gggtacatcc actgttccat ttacttcagc taaagataaa ccatttgtat
     1681 gttcaataag tcgatgctta tgaaattgtt tgttggattg attattcaag aaaaaaccac
     1741 ctttcctatt tatctacgat tacattctac acctcagaaa gaaaaaatta aagaaaaaga
     1801 tttggtatgc ctaatttttt ttcgtggcgt gtcttgctgg ttaatgaaag aaattttgtt
     1861 cttctctaaa aaaaccacta ttttttgcat gaaactaaag aatacgcctt tcttttttca
     1921 ataaacttta gtaaaataaa tcattgagag caattcggaa atagaaagga gagatttata
     1981 tggtatcaac aggtattgtc gtacttattg ctattattgc tttgctaatc ggcgcagtag
     2041 gtggcttttt cctagcgcgt aaatatatga aagactattt agaaaaaaat cctcccgtta
     2101 atgaggacat gttgcgatca atgatgatgt caatggggca aaaaccatct gagaagaaaa
     2161 ttcgccagat gatgcagcaa atgaagaacc aagggaaaaa ataggttctg acccaaagac
     2221 tttttgcggg ctgatttttt cagtccgttt tttatttcgt aatttgttag actattcaga
     2281 ctattcagca aaaaagacaa gcacagacaa tcctatgctc ttgataaaga caaaggagga
     2341 gtaaaatgtc gatttttaga aaattaggtt ggttttttcg acaggaaaag aaacattatt
     2401 taattgggat tttctcccta ttcgcagtgg ccttggtaca gttagctcct ccaaaagtga
     2461 ttgggatcat cattgatgag atcgccgata aaaatttatc aataaagatc atttcctggt
     2521 ggatcttatt attgatcctt gcagctctct tacaatatct ttttcgttat atctggcgga
     2581 cgaatatttg gggaagtgca gctcggttgg agaaagaact tcggcagcag ctattcaaac
     2641 attttacaga aatggacaat ctcttttacc aaaaatatcg gactggagat ttgatggctc
     2701 atgcaacgaa tgatttgaat gcaatccaaa atgtagcagg agctggtatc ttgacctttg
     2761 cagattcagt gatcacgggc ggaacaacga tcattgcgat gattttgttt attgattggc
     2821 gcttaacact gattgcgctg attcctctgc ctttactagc cgttacttca cgagtgctgg
     2881 ggtcaaaact ccacgatgct tttcgtgatt cgcaagaagc tttttctagt atcaatgata
     2941 agacacaaga aagtattact gggatcaaag tcattaaaac atttggacaa gaaaaagaag
     3001 atctcgcgga ttttgaagaa aagattgaag atgcaattat taaaaacaaa cgagtcaatt
     3061 ttttagactc cttatttgat ccattcatta ccttgattat cggtctgtct tatgttgcaa
     3121 caattatttt aggtggaaag tatgtcttgg aaggcacgat ctcaatcggg cagatggtct
     3181 catttattag ctatatcggt atgcttgttt ggccgatgtt tgcgattggt cgattgttca
     3241 acgtattgga aagaggaaat gcttcttatg atcgcgtcaa tgaacttttg catgaaaaga
     3301 cgcatatcgt ggaacaactg ggtgcagtgc agactccggc aaaaggcgag ctgaatgtag
     3361 ctatttcctc ttttaactat ccgaaagaag aatcaccagc attagaacaa atcaaatttg
     3421 cgatccaaga aggagaaaca ttaggtattg ttgggaaaac tggtgcggga aaaacgacaa
     3481 tcatcaaatt actgatgcgt gaatacgatg attatcaagg aaaaattcaa tttggcggat
     3541 gttcgatcaa agaatattca ttgaatgctt tattaggatc aatcggctat gtgcctcaag
     3601 atcacttctt gttttcgatg accattcgag ataatatccg tttttctaat ccaaaacttt
     3661 cagaagaaga agtagagcat gcggcttctt tagcatttat caacaatgaa atcaaggaat
     3721 taccaaaagg ttatgatacc ttagttggag aacgtggagt ctctttatct ggcggacaga
     3781 aacaaaggat ttcgattgct cgagcattga tcaaaaatcc tgaattgctg atcttagatg
     3841 atgcactttc tgcagtagat gccaaaacag aagaagctat cttgcataat ttaaaagaaa
     3901 taagaaaaga gaaaacaacc atcattgcag ctcaccgttt aagcagcgtg atgcatgcaa
     3961 aagaaatcat tgttgtcgat caagggaaaa tcattgaacg aggaacccat catgagctgc
     4021 ttgcattagg cggctggtat gaacgaatgt gggagaaaca gaaattagaa gcgaagatag
     4081 aaggaggcga ggcctgatgg atgaaaatta tcaatcggaa tggacaaaat cgattccact
     4141 taaagaacag aagaagatca tcaaacgact gatgaagttc gccaaacctt ttagaagaac
     4201 gttcatcgtt gctatcttat ttgcgtttgc cctgtctgtg atcaatgtcc tattgccaag
     4261 gatcatccaa acttttatgg atgatcatct ggctaaacag tcggctacga cacaagttat
     4321 tttgtttttt gctggtatgt acttgtttgg agtcatagtc aaaagtatca tttggttttt
     4381 ccaatggtat ttgtattcca tggcttcatt gaagacctat cagtatgttc gggtaagatt
     4441 atttgaaaag ctgcatacac taggtatgcg ttattttgat cagacaccgg caggatcgac
     4501 tgtttctcga gtgacaaatg acacagaaac gctatttgaa ttttggtatg tctttttgat
     4561 ggtattgact gggatctttg cagtcgtttc ttccttcatt gccatgtttc aaatcaatgg
     4621 agaaattgcc ttgtggactt tggtgttctt gccgatttta ggaatcgtca tctggtatta
     4681 ccagaaattc agttctcgta tttaccggaa tatgcgggaa aaattaagtc agctgaacac
     4741 gaaattgaat gaatcgattt ccggcatgcg tattatccag cagtttcgcc aagaagctcg
     4801 tttagctaaa gaatttgaac aagtgaacaa cgagtattta gacacgcgct atgcgatgat
     4861 caaaacaaat tcgattctgt taagtccgat catcaatttt ctatatgcat tggcgattgc
     4921 gttggcgttg actttgtttg ggatcgatgc gctgcattct cccgtagaag ttggactgat
     4981 ctatgcattt acgacctatg tccagggatt ttttaatcca atgtctcaaa tgatggactt
     5041 tttgagcacc tttacagatg gaatggttgc cggtagtcgt attttgaaaa tcatggatac
     5101 agaagaatat gcaccgcaac aaaatcctgg agcagatcaa gcgattactt caggtaagat
     5161 cgagtttcgc aatgtaagct tttcttatga tggagagcac aatgtattga acaatatctc
     5221 ttttgtcgct aatccgggag agaccgttgc attagtgggg cacaccggaa gcggaaaaag
     5281 ctcgatcatc aacgtattga tgcggtttta cgaattttat gaaggccaga tcttgattga
     5341 tgatcatgac attcgagaat atccaatgga agagttacgt aagaaaatgg gattggtctt
     5401 gcaagatgcc ttcttgtttt atggagatat cgcaggaaat atccggatga tgaatccaac
     5461 tatcacagac gaacagattc gccatgcagc tgagtttgtt caagcaaaca agttcatcga
     5521 tgaattacca aaaggatatc actcaaaagt gatcgaacac ggtgccagct attctagcgg
     5581 acaacgacag ctgatcactt ttgcgcgaac aatcgtgaca gatcctaaaa tactagtatt
     5641 ggatgaagcg acagcaaata tcgatactga aacagaagga ttgatccaag aaggattgac
     5701 aaaaatgcga caaggacgga caacgattgc gattgcccat cggctgtcca cgattcggga
     5761 tgcagaattg attttagttt tagacaaagg tcatatagta gaacgtggga atcatgaaac
     5821 acttctagcg caaaatggtt tgtatgcaga tatgtacaaa ctgcaaagca gtggtgtgta
     5881 aaaagtggtt gtgacagggc tccgttcagc tttaggtgat aagaaaaaaa ttgtaaaaaa
     5941 ggctttccag atttttgcat aaatttggct tatcaccgat aagctggtac tggaacaccg
     6001 tatattagaa gttgggacag tagcatagta gcattttgac ctaagcgcta gagtgaaaat
     6061 aaaacagagc ttcccagatt cttcatctgt gagcgttagt gtcgtaatta ccagatttaa
     6121 aaaaaatcac gacagctagt cagaagtgcc caatagccgc taagaaagcg ttgacaaaag
     6181 tgcttgcttt cgataatata aagaaaacga tacaacttgg atagtgattg cctgatgcaa
     6241 gctaaacctg atgagtctcc catggttcca tggacggctt tttgggtttt tctttttgtt
     6301 ttggatacag ccctatatat catggaaagg agtaaaacat gctgattgag aaagtactga
     6361 ataacaacgt cgtaataacc agggatgaaa gaaatcagga aatgatcgtg atgggaaaag
     6421 gtttggcatt caaaaagaaa gtgggtgacc cgatttttga ctcatgcatc gacaaaaaat
     6481 ttcagttgac aaatgacgga ctttcacaac agttccaaga attggcacaa gcgattcctc
     6541 ttgagtactt agaaatttct tgtgaaatca ttgaatatac aaaagaggct ctacaagtcc
     6601 agttgaatga ttcggtgtat attgcattga cggatcattt gtatacggct atcgaacgtc
     6661 acaaaatggg aatatttgta ccaaatgtat tgctgtatga tatcaaacaa ctatttccta
     6721 aagagtatgc catcgggaaa aaaacagtga agaaaatctc ggataaatac cacatcaagt
     6781 tatcagaaga tgaagccgga tttatcgcat tgcatttagt caatgcacaa ggcattcaaa
     6841 gccaacaaga caatacctac ctgtttacta caacaataca ggatattcta aatatcgtcc
     6901 gctattacta taagattaca tttgatgaag attcagtcca tttttttcga ttcgtcacac
     6961 acctacgttt ttttctgaca cgcgtcctag atggagaaaa atcagaagtg ggagaagttt
     7021 ctgaggaatt gtaccaggtt attcaaaaaa aatataagga tacgtttggt tgcgttgaga
     7081 aaatagcaga ctttttagcc gagatattca actaccagat gtccacggac gaaaaaatgt
     7141 atttaacgat ccatattgcg cgtttagtgc atgagaatcg ttgtaaataa ataaaaaaag
     7201 gaggataaat taacaagaac gcatgaaata agggtagtga cattcagttg gctaaacctt
     7261 ccactaataa attggaggga atagaaatgg gaaaatatca agaattagcg agcaaaattg
     7321 tagaaaatgt cggcgggaag gaaaatatca atggtttgac acattgtatc acaaggcttc
     7381 gtttcaaatt aaaaaacgaa gaaaaagcaa atgatgagat cttgaaaaat atggacggtg
     7441 ttgtgacggt aatgcgagcg ggaggacagt accaagttgt catcgggaat catgtgccag
     7501 tcgtgtttga agaggttata aaagcaggaa accttacttt tgatgaggct gtttcaacag
     7561 aaaaaatgag accgtttgat atgcttattg atggaatatc gggctgtttc cagccattcc
     7621 ttgctattct agctgctggt gggatgattc gtggactgac agcattactt gtcttcttag
     7681 gcgcatttga ccgcggttct ggcacatttg ttatgtttga taatatcggt gattctgtat
     7741 tccaatttat gcctgttatt atcggtttaa cagctgcccg taaatttaaa gtaaatgaat
     7801 tcgtagggat gttgcttggg gcagcattaa tgaatcctag cttgtcgctg gaagctttga
     7861 gtggtgcagc agaagcacca ctgactacca tattttctgg cactattttt gaagcaccta
     7921 tttatcaaac agtattcggc attccctgga ttgcgcgtaa ctacgcttct tctgtcattc
     7981 ccattatctt tattgtgttg ttagctagcc aaattcagaa accaattaaa aagttagtac
     8041 ctgagatgat cgcgaatttc ttcgttccat tcttcaccgt tcttattaca atgcccttag
     8101 gttttttact cgttggacca gcattcacat tcgcaactga tattttaatg gctggatttg
     8161 aaacactttt agcactttcg ccagttattt atggagcaat cgtaggcttc ttctggcaaa
     8221 ttctagtgat gtttggtctc cattgggcaa tcgtaccaat gggattgatg caattttctg
     8281 tgaatggttg gcaaaatatc atgacacctg ttgcagtagt gtcttttgga caaactgcag
     8341 cacttactgc actctacttt aagcttagaa acccaaaaga caaagcaatc gcaataccag
     8401 ccattgtttc tggtattgtg gggattacag agccagctat ttatgggttt acattgccac
     8461 gtaaaaaaat atttattttt acctgtgtcg gtggtgcgtt agggggcgcg tatagtggat
     8521 taatgaattt aacttcttgg aatccaggtg gattaggcat ctttacaatt cccaactata
     8581 ttagaccaga tggtgattta acggatgtga ttaatgtatt gattggaatc gccattgcga
     8641 tggtggtatc ctttgcgctg acttttttct tttggaagga ggaagcaggt gaaacagatg
     8701 atagacagaa aagatcaggt aaagaaattg taaaaacacc gatacaagga caaatcgctc
     8761 cactgaatgc agcaaaggat gcagcttttg cacaaggaac actaggtcga ggaatcttga
     8821 tctaccctga aaaaggagaa gtacgtgccc cttttgacgg aacagtcatg accctgttcc
     8881 cgacgaaaca tgcaatcgga atggtttctg aagcaggtct ggaattgctg attcatgtcg
     8941 gattggatac tgttcagttg gaagggaaat attttgaaag cttggtgcag caaggagaaa
     9001 gagtgaaaca aggcgatctg ttgctccgct tcgacaaaaa gaaaatcgaa gaggaaggat
     9061 acagtttaga aacacctgtg atcgtcacca attacacgga ttatttggat attttggaaa
     9121 atcaagggga gacggtcggg ccagacgatg cacttatcac cgcactgacc tgaacggtta
     9181 ggtgaaagaa tggactaggc ttaattattc tttttagtcc acttctttat tttcaaaatt
     9241 gaaaggctct ttcatgatgg ctgagctgat agggcgttta tcaaattttt gtcctacaga
     9301 aattagatgg actaaattct gttgataatt ttctgcaaaa acacaactat ataacacgtc
     9361 tagaagataa caaatcgatg tattgatcgt aaaattacca attttcgaat acagtcgttc
     9421 gcgtgtcgta agtcgcaaag cggctgtact cattgaagat agcgttgaat caccgatact
     9481 ggtcaaagct aaaattggaa catgattttg tttcaatatt tctgcggtac gaaggatcac
     9541 attgttttca cccgtataag aaatcagaat cccgcacata tcactcgtgc aattgtacgc
     9601 ttcatagaac gattcaccaa aagtggtgac aatcgtgaca tccattttga tgcgcttcat
     9661 tttcagcatg aaatcttgag aaatcaaagt attcgagtta ctggcgaaaa tcacgatttt
     9721 ttttgcttga agcattagtt gtttggcttt ttgcagttgg tcatgatgaa tgagagaaag
     9781 tgtatcttga atcgtcatct gttctaaaga agccatttta tttgcgatcg tcataatacc
     9841 gtctgtggtg gaaaaaggaa gattcgcatc tacgtcttga aaattccctt caagataggc
     9901 tgtttcagct aaaaaagcat tacgaaaact gacccagcca tcaaaaccca ttttttttgc
     9961 tacacggatg agtgtggacg ggtggacata acatcgctca gcaatctctt ggatggtcat
    10021 ttcgccaagt gctggagaat cgcttaagag aaactgaatc acttcatttt ctgaaggaga
    10081 aaaggagatt tctttgattt tttcacgtaa taacatgtag ataccttctt cttgtttttt
    10141 tacgtaaatt ataacttttt tgaaaatgat ttgtaaacgg atttatgtta tatagcttaa
    10201 taaagacatt ttttgacaag atatttacaa aaatccagta gaaaacacta acttttgtaa
    10261 atgttactgg aaagaaacga atttctattg tttgttttgt ttacaaaaaa gataataaaa
    10321 gtgtaaaaag taaaggagtg agaacatggc aaaaggaatc aaaatcgcta cgattggtgg
    10381 aggcagcagt tacacccccg agttgatgga aggatttatc aaaagatatg aggaattacc
    10441 gatacgagaa atctggctcg tagatgtaga agaaggaaaa gaaaagcttg agatcgtcag
    10501 tcagatgtct cagcgtatgt gggatgcttc tccgtatgaa gtcaaaatct atgcaactct
    10561 ggatcgggaa gaagcattga aagatgcgga ttttgttacg actcagtttc gtgtcggtca
    10621 attagatgca cgaatcaaag acgagcggat ccctagttat tatgggatga ttgggcaaga
    10681 aacaaatggt gctggcggga tattcaaagc ttttcgtacc gttccagtgg ttttggcaat
    10741 cgttgaagac atgaagcgtt tatgtccaaa tgcttggctg atcaatttcg cgaacccaag
    10801 cgggatggtg acagaagcag ttatcagata tggcaaatgg gataaagtga taggattatg
    10861 caatgtgcca gtaatggcga tgatgacaga accaacaatg cttggcaaga aaaaagaaga
    10921 gctgatctac aagtttgccg gtctaaatca cttccattgg cacaaagtag cagataataa
    10981 aggaaatgac cgcacggcag aattgattga tcgtttatac gatgaagaca atggattgcc
    11041 gaaaaatatc tttgatatcc cgtttttcaa agaacaatta aaacaaatga acatgatccc
    11101 ttgtggctac caccgctatt actaccgtga agaagaaatg ctggaacatg ctttagaaga
    11161 atatcaaacg attggtacaa gagcgcagca agtgaaagaa acagaagcag agctgtttga
    11221 attatacaaa gatccagaat tggatcataa acctgaacaa ttgcaaaaac gaggtggtgc
    11281 ttattattca gatgctgcct gtgaaacgat tgcttcgatc tatggaaata aagaaacaca
    11341 gatcgtggta tctacaaaga atgatggagc tgttcctgat ctgccggcag attgtgtagt
    11401 agaagtcact gcctatgttg gcgcacaagg cgcacgaaat gtagcgtttg gttcccttcc
    11461 tgctgctgaa agaggctggt tgcaagtaat gaagaatatg gaattgctga cgatcgaagc
    11521 agctgtgact ggtgattatg gaacagcttt acaagcgttt acgatcaatc cgcttatacg
    11581 atcaggaaag acagcaaaac ggatcatgaa tgagttgttt attgcacatc agcagtattt
    11641 accgcaattc aaggaaacaa tcagccggtt aaaagcagaa ggaatcgaag tccaagatga
    11701 actggcaaga gaattatcaa gcaatacaca tgtaatggag gaagtatgat gggattcaga
    11761 aaagattttt tatggggcgg agctacagca gccaatcaat gcgagggcgg ttatgatgaa
    11821 ggcggacgtg ggttagcgaa cgtagatgtt gtgccaatcg gagaagaccg ttttcctgtc
    11881 attactggaa aaaagaaaat gtttgaattt gatgaaaatc atttttatcc agcaaaaatt
    11941 gcgatcgata tgtatcatca ttataaggaa gatattgctt tatttgcaga aatggggttc
    12001 aagacttatc ggatgtccat tgcttggagt cgtatttttc caatgggcga tgaaaaagag
    12061 ccaaatgaat ctggtttgaa attttatgag gatgtcttta aagaatgtca aaagtacggg
    12121 atcgagccgc ttgtgacgat tacacatttt gattgtccga tgcatttgat caaagaatat
    12181 ggtgcgtggc gttccagaga actcgttggt ttttatgaaa atctgtgccg agtcatcttc
    12241 aatcgctata aaggacttgt caaatattgg ttgacattca atgagatcaa tatgatcctt
    12301 catgcaccat tcatgggcgc agggctgtat tttgaagaag gagaaaatga agaacaaatc
    12361 aaatatcaag cggcacatca tgagttggtt gcaagtgcca tcgcaacgaa gattgctcat
    12421 gaagtagatc cggagaacaa agtaggctgt atgctggcag caggagcata ttatccatac
    12481 acttgcaatc ctgaagatgt ttgggcttct agaaaatcag atcgagaaaa ttatttcttc
    12541 attgatgtcc agtcacgagg agaatatcct gcttatgcat tgaaagaaat ggaacgaaat
    12601 ggcattcaga tcaaaatgga acctggggat gccgcattgc tgaaagaaca tactgttgat
    12661 tttatctcct tttcttatta ttcttctcga gtttcgacta ctgacaacga actcttggaa
    12721 cagactgcag gaaatatctt tgcttctgtc aaaaatccat atctggaagc aagtgaatgg
    12781 ggttggcaaa ttgatccatt aggcttgaga ataacgatga atgatattta tgatcgttat
    12841 caaaaaccac tatttattgt agaaaacggc ttaggtgcag tcgatacgcc cgatgagaat
    12901 ggttatgtgg aagatgacta tcgaatcgac tatctggcag cacatatcca ggcaatgaaa
    12961 gatgcagtag aattagatgg agtcgatcta ttaggctata cgacttgggg atgtattgat
    13021 ttagtatcag ctggtacagg tgagatgaag aaaaggtacg gattcattta tgtcgatcgt
    13081 gacaacgaag gaaatggcac attagcccgt tcgaagaaga aatcattcaa ctggtataaa
    13141 aaagtaattg attcaaatgg agaaaatctt tcgaatgatt gatcaatgat ttataaaagt
    13201 ctattgtttt tcagcggatt tttcgagtat aataaagcta ttcgagaaac gcaagcagaa
    13261 caatagactt tttttcgcat tggctgtaaa gtatgcttac ttgattaagt aaaggagaat
    13321 ctacatatgt atgatgtaat cgttattggc gcaggtcctg ctgggatgac tgctgcttta
    13381 tatgcttcac gttcaaactt atccgtattg atgatcgaac aaggcgcccc tggcggccaa
    13441 atgaacaata cggcagaaat cgaaaactat cctggtttcg attcaataat gggtcctgat
    13501 ctagcttata agatgtatga aggtgtttca agatttggga cagaaaatgc ttatggaatc
    13561 gtgcaagata tcaaggatca cggcagccac aaagaagtta tttgtgaaga taaaacttac
    13621 gaaggaaaaa cagtcattat cgcaacaggc tgtatccacc gtaaattagg cgtacctggc
    13681 gaggaagaat ttgctggacg tggcgtttct tactgtgcag tttgtgatgg tgcgtttttc
    13741 cgtaacaaac gtctagtagt gatcggagga ggagactcag cagtagaaga agccatctat
    13801 ttgacacaat ttgcttctga agtagtcatc gtccaccgta gagatgaatt acgtgcacaa
    13861 aagatcatcc aagaccgtgc atttgcgaat gaaaaaattt cctttatgtg ggatacagtc
    13921 gttgacgaaa tcgttgggaa tgaaatggta gtgacaggtg tgaaagcacg taatgtcaaa
    13981 accggcaatg agtttgattt ggcagcagac ggagtattca tctatgttgg actggatcca
    14041 ttaactgcac catttagaga agcagggttg acgaacgaag ctggctggat tccaacagac
    14101 aacgaaatga agacgaatat accaggcgtt tttgccatcg gagatgttcg tgaaaaagat
    14161 ttgcgacaaa tcactactgc tgttggtgat ggtgggatcg ctggacaaca agtgtataaa
    14221 tacttggaat ctttagaaga aacaactgca taagtttaaa aagagtggaa gaacggttta
    14281 attgttcttt tactcttttt tttcgcgtga aatctactga atccgattta tgcgaatact
    14341 tgcaaccgtg cttgataaaa gaatcctttc ttgatttaag cgttttttgg tcctcatact
    14401 ttcatatcta ataagtgaat gctatactta ttaagaacca tatttcagaa agaggtgtta
    14461 ttttcatgtc ttgggaacaa gtgtatgaac aatgggtaca tgaagaaaat ttagaagaaa
    14521 acttaaaaaa acaattaaat gatctgggtg aagatcctga aaaacttgaa gatgcttttt
    14581 atgcaccgtt ggaattcggt actgcaggca tgcggggaat cttagggcct gggatcaatc
    14641 gaatgaacat ctatacggta agacaagcaa cagaaggact tgcacgtttc atggatacac
    14701 aaggcgaaga aacaaaacgc cgaggtgtcg ctatcgctta tgactcacgc catcaatcac
    14761 cagaatttgc catggaagca gccaaaacat tagcacatca caatatccca tcttatgtat
    14821 tcgaaagtct acgtccaaca ccagagcttt cttttgcagt ccgtcatttg aagacgtttg
    14881 cgggaatcat ggtaaccgca tcccacaatc cagcagctta caacggatat aaagtctacg
    14941 gagaagatgg gggacaaatg cctcctgcag acgcagatgc attgacgaaa tatgtccgtg
    15001 aagtcagcaa tccgttaaaa gttgaagtat tatctgacga agaagctgaa catagcggat
    15061 tgatcacgat catcggagaa gaagtggatg ccgcttatct agaagaaatc aaagcagtaa
    15121 cgattgatca tgaattggtg gaaacaatgg ggaaagattt gaaacttgtg tacacaccac
    15181 ttcacggaac aggaaaaatg ttgggcgaac gtgcgttgaa acaagctgga ttcgaacaat
    15241 tcgtactagt tccagaacaa gctgtcgcag acccagattt cactacagtc aaatcaccaa
    15301 atccagaaga acactctgct tttgagtatg cgatacgact tggcgagaaa gaaggcgctg
    15361 atttgctgat tgcaacagat cctgatgcag accgtttagg tgcagccgtt cgtttgccaa
    15421 atggctccta tgaagtattg accggaaacc aaatcggagc actgtttgct caatatattt
    15481 tggaagcaca ccaatcgcga ggcactttac ctgaaaacgc agcggtattg aaatcgatcg
    15541 tttctagcga attacctaca gcaattgcgg aacactatgg ggctaccatg ttcaatgtat
    15601 tgacaggatt caaattcatt gctgaaaaaa ttcaacaatt tgaagaagat cattcccata
    15661 cttttatgtt cggattcgaa gaaagttacg gttatttagt taaacctttc gttcgcgaca
    15721 aagacgcgat ccaagcattg ctcttattag cagaagtagc agcttactat aaaaaacaag
    15781 gcaaaacgtt gtatgatggc ttgcaaacga tttttgaaac ctatggctac tacgcagaaa
    15841 aaacgatttc tgtgacaatg agcggacaag aaggttctgc gaaaatctct gctttgatgg
    15901 aaaaattccg tgaagaagca ccaacagaat ttgccggagc aaaagtcatc caaacagaag
    15961 acttcaaaga gttgacgaga acagaccgtg aaggaaacgt agaaaaacta acgacaccgc
    16021 catctgacgt attgaagtat acgctggaag aaaatggctg gatcgctatc cgtccttcag
    16081 gaactgagcc gaaaatcaaa ttttatatcg gtgtaaaagg aaactcttca gaagacgcag
    16141 ctgaaaaagt agccgcttat gaaacgatta tccaaaagat gacagaagaa taaaaaaact
    16201 tgagactgat ggaaaaagtg gtaaacttta gaagtcagtc ttttttcaag ttggaggtga
    16261 atggattgcc agacacgcaa aaaacaaaag tagagaaagt cagccaacta ttcaaaatgt
    16321 tgagtgaccc cactcgtctc aaaattctgc tgtatctgaa agacggggaa caaaatgtga
    16381 cagcaatcat ccaagcagtg gaaatggaac aatctgctgt atcgcatcaa ctgcgtttat
    16441 taagagaaaa ccatgtcgtc aagtcccatc gtgagggaaa agcgattttg tatagtcttg
    16501 atgattctca cgtactggat attttgaacc agacactcaa acatgtggaa catcaataac
    16561 gataggtgca aatagagaca aactggactg tgtcaacgaa tcttcttcgc tgacacagtc
    16621 cagttttttt aaagaaaaat tgttagtctg tttcttcggt ggtttcagtt ccataataac
    16681 tatggtcttc taggtctaaa gcattcaaaa taagcgaagc tgtttcttca atagataaag
    16741 aagcgacatt gattactacg cagcccaatt tttcataaag atcattcgca aaatcgagtt
    16801 cagctcgtat tttttcgata tcggaataag cagtatcagg atttaatccg taagagcgca
    16861 tccgttcttt acggatattg tttaaaatat ctgggttatt cgtcagtccc acgatttttt
    16921 taggatcgat ctcccaaagc tgtttgggaa tatgtgcttg tgggatcaaa ggtagattgg
    16981 caacttttaa atttttgtta gctaaaaaca agctcaaagg cgttttggaa gttcgggata
    17041 cgcctagcaa aacgacatct gcttctagaa acccacgagg atctttcccg tcatcgtatt
    17101 ttacagcaaa ttccattgct ttgatccgtt tgaaatagtt ctcattcaat aaatgaaggg
    17161 cgccaggttg ccgaatgggc ttgataccag ttaagcgctc gatttctgat atcggcggag
    17221 tcatcacatc aaaactaaat aattgatgtt cttcacaaaa agaacgcgtc atctcgatca
    17281 attcttgatt gatcaatgtg tgcaggacaa gagctttttc ttctagtgca tcttgcagtg
    17341 cctgcatcaa tgttttctca tctgtcacaa atgttctgcg gaataaattg aactcaacgc
    17401 taggatattg ggccatagtg gcttgcgcta gttttgtcgc agtttctcca gcagagtcgg
    17461 agatgacaaa aaaagtaacg atttctgtag aatcggaaga catggataaa acctcacttg
    17521 catttttttt atgtttatta taccatactc tagaatgtgt acttcgtaat cattttgatt
    17581 tggaggaata agtcatgaaa aaacagacgt tgatcgaaca atcactagaa acattgaaaa
    17641 ataacggttt taaatatact aaaaaaagag aagcattgtt aacttattta gtgaagcgca
    17701 atcgctacgt atccgctaaa gaagtttttg actatatgaa tcaggaattc aaaggagtaa
    17761 gttacgatac gatttatcga aatctccatg attttgcaga aatcgattta ctggaagaaa
    17821 ccgatttaaa tggagagatg aagtttcgtt ttcattgctg tcaaggggaa atcggccatc
    17881 accatcactt tatctgtacg gtgtgcggaa caacgaaaga aatccatatg tgtccaatga
    17941 attatttcga agaacagctc ggtggatgta cgatcgaagg gcatagattc gagattttcg
    18001 gaagatgtga aaattgtcaa taaggattta aataaaataa catttgataa ttttaaaaaa
    18061 aagcaagatt tccttgacgg tcaaaacagc attagatata atatttacag gacagtcttg
    18121 ttttttgaga tatatttcaa taacaattac ggttactttt taagctcgga gggagggaat
    18181 taacatgtca aaaacagtcg ttcgcaaaaa cgaatcactt gacgatgctc ttcgtcgctt
    18241 caaacgttcc gtgtcaaaag cgggtacttt acaagaatct cgtaaacgtg aattctacga
    18301 aaaaccaagt gtaagacgca agaaaaaatc tgaagcagct agaaaacgca aaaaattcta
    18361 gttctgtgat gaattggagt tggtagtgtg tcactactaa gtagattaaa cgatgacatg
    18421 aaaacagcga tgaaagcgaa agataaggaa tctttacaag tcatccgaat gatcaagtca
    18481 tctatacaaa acgagcagat taaagaaggt cacgacttga cagaagaaga agaattaacg
    18541 gtgttgtctc gcgaaatgaa acagcgacgt gattctttgc atgagtttga agaagcagga
    18601 cgtgacgatt tagctgaaaa agtaaaaagt gaaattgtga tagtcgaaaa atacatgccg
    18661 gaacaacttt ccgacgaaga aattcgacaa cttgttcaag aagcaatcac gcaaactggt
    18721 gcttcatcaa tgaaagaatt tggcaaagtc atgggtgcga tcatgcctaa agtcaaagga
    18781 aaagcagatg gaaaccaagt aaatgccatt gtgaaagaac tattacaatc ttaattttat
    18841 catttaaact gcggacaatc attgtccgca gtttttttgt gctcgtaaaa aagagatcta
    18901 aaaaatagct agacgaaaga ataggattct ttcatctagc tgtttttttc ctgtttaata
    18961 tttcttatgt taaattgtgt ttgatctggt tattcttctg gtagttcatt tgcttcttgt
    19021 ttataccctg ataggcgata ggcgtaatag aagagtaagc tgccagcata cccaagtaac
    19081 gttgggacca tccagccaag tcccaatgca gcaaaaggaa cgtgatgatg ataaaattcg
    19141 agcatgcttg ctacaactct ttgttgactc actaaagcag gcgaatttgc cagcatatcc
    19201 aatacggcgg gaacagcagc aaacaacatc gttacttgat agacaaatgg tgtcttttgg
    19261 aaaaattttg ctgttaagga aagcaaaatc aacgcaagcg acaatggata caaaagcatc
    19321 aatactggta aagaccattg gatgatattg tccaaaccag catttgcaac gacaaaagag
    19381 acgaaagtcg ttaaccgcag ccatgtcata taactgactt tagggaacag tttatggaaa
    19441 tcttgtgcaa aagaaacaac gagtcccata gcggtagtga agacacctaa tgtgaccatc
    19501 actcctaaga agctagcgcc gaagttacct aaataaaaat tagtgatctg agaaagtgca
    19561 gttccgccat tttctgataa agacatctta ttcaaactca tcgcaccgag aagaacaaga
    19621 ccaaaataga tcatgacttc tagcgcaacg ctcaggctac cagcttttgc tgttaattct
    19681 gtgacttttt tatctttgaa accaaggtca cggactgcat ggacaaaagt gacacttaag
    19741 gcaagcaagg ctactgcatc aaccgtgtta taaccttcta ggacaccatt tgttaaagcg
    19801 tttgtttggt aagtatctgc agcagattga tttagatttc ccattgggtg gaataaagaa
    19861 acgacaaaaa tgattgctaa taatgcaaga aacaaggagt ttagatactt tccgacgtat
    19921 ttgaccaacc gtgtgggatg gacagtaagg aaataagcaa gtaaaaagaa aagagcagag
    19981 aataaaaaca tacctaatga attatatttt tcaggcaaaa atggtttagc agccatttca
    20041 aaagcagtag cagctgtccg tggtgtaccg aaaaatggtc cgatcgtcaa atgaacaagg
    20101 attaagaaca aggcagcata ccattttccg acaggtttag ctaagtcata cagaccatca
    20161 ctttttgtca ctactacagc taagatagct agtaatggga aaagagcgcc tgagatggca
    20221 aatcctacgc cagcactgac ccagtttgcg ccagccattt gacctaagtg gacaggaaag
    20281 attagattac ctgacccgaa aaacatcccg aagataagtg aactgaccat caatagttgt
    20341 ttccatgaat aagtttttgt ttcttccata aatttttcct ccaataatta tcattttgat
    20401 tgacgatata aacgttgcag caattagtaa tgccactaat atcagattcc atgaaaacca
    20461 ccaccttaaa atataaaaaa aagccctttt ccacttggga aaagggctct agattctaga
    20521 acggtaccac cttttttcgc ttaaaaaagc ttcttcattc acggacgctt tttgataaag
    20581 ttatccgcta gcctgataat ggaggcagcc acaatgatct acgttttcga cattgactcg
    20641 gaaatgatgt tcgtctattc gatttattgt catttctcac ttacatgact cactgggaat
    20701 aaatcgttga atagcctact gttttcctcg acgctttgct gtatgtttat ttgttgacgt
    20761 aataatacac ctgttttttt tgaaatgcaa gaatatttta actattttgt tttctttttt
    20821 tgaaacaaga aaaataccta gagaatacct ctgaatgaaa cggaatattt tgttctccac
    20881 tttcatataa cttacattct cagattcttt ttatcaaaac gagaccttta gcgaatggaa
    20941 acagctattt tttaacgttt cttggtacgt atggttaaac gactctttta caaccttttc
    21001 ttatttgcta tatagtttct tctgagtatg gtaaaatagg aaagaatgaa tcgaaaaaaa
    21061 ggggatgtct atttttgacg gaagagtcta gttctttaga gattagattg acagctgctg
    21121 atgatgtcag catgctttta ggtgcacacg acaagcatat aaaactgatc gaggaaacaa
    21181 cggaaacaac catccataca cgtggagaaa tcattcagat cattggtgaa caatcccaga
    21241 tttccttggc tgcctcagtc attcggacat tacaggaatt gatcaaacga ggaatccacg
    21301 taagtacacc agatgtcgtg acggcattga aaatggggca aaaaggtaca ttagattatt
    21361 ttgttgagat gtatgaggaa gagatcgtca aagaccgtaa tggaaaacct atacgggtaa
    21421 aaaacagcgg tcaaaagaaa tacgttgaat cggtagccaa acatgacatc gtatttggtg
    21481 tagggccagc cggaacaggg aaaacgtttc ttgccgtagt attagcaatt gctgccctaa
    21541 aaaaaggcga agtgcaaaaa atcattttga cgcggcccgc tgtagaggca ggggaaaacc
    21601 taggctttct acccggggat ctgaaagaaa aagtggatcc ttatctgcgg cctgtttatg
    21661 atgctttata ccaaattttt ggattggatc atacgaaccg attgatggaa cgaggcgtaa
    21721 tcgaaatcgc accattagct tacatgcggg ggcggacatt ggatgatgca ttcgttatct
    21781 tggacgaagc acaaaacacg acagtcgctc agatgaaaat gttcttgacc cgtctcggtt
    21841 atcaatcaaa aatgattgtc aatggggata caagtcagat agacttgcct cgagggacga
    21901 caagtggtct tgttcatgca gaacgaacac taaagcaaat caaaaaaatc gattttgtta
    21961 attttgaagc aagtgacgtt gttcggcacc ctgtagttgc cgaaatcatc aaagcttatg
    22021 aaaaggcgga tcttcatcaa gaataagctt tgcttaggag gataagcaca tgttgaataa
    22081 aacactgcag aaactacaag aaaaactcgg aaaggcagca ttgcctttcc ttctgttctt
    22141 gttttttatc attgtctgcg gcgttacatt tagtagtgtc aaacaaaagg ccaatgattt
    22201 cagagaaggc caagtagcag aagagagtat ccgtgcgaat aaaacgatcg agaacacgga
    22261 agaaaccgaa caaagaagaa aactggcagc agaagcagtg actccagaat atacttatca
    22321 aaaagatctg gcagatgacc agaacaatcg gatcaagcaa ttattcgaat tgatcgataa
    22381 gacgaatgat accatcaaca aatcttataa tgacaaggta gataaggcga aggaagatga
    22441 aaatatcccg aaacctacta cagaagagcg gattgctaca ctgaagaaaa attttgaaaa
    22501 cgtgaatgca gaaaacgttg cgttttacca aaaactgccg aacaattttt attcgacgat
    22561 atttgaaatg actgaaacgg aaattcacac ggttagggat gaaagtttga agctcattga
    22621 cgaacagatg agtaaacaag ttcgtgaaag cgaattggaa gcttttaaac aagaagcaga
    22681 agatcagatt cagtatttga atgtcacaac agagcagcaa caaatgattc gctacttagt
    22741 ggatcaaggc attgtagtca atgatgtatt gaatgagaaa aagacagaag aattaaaaca
    22801 atctgcacga gaagctgtac aaccagtgat gatcttccaa ggagaaatca ttgttcgcga
    22861 aggaaatcaa attgatgctt cagcgatgaa aaaattggaa ttactaggat tgacgaatca
    22921 aacgacttcg attttcccac tcattgccat ggttttagct gttttgcttc aaatcggcgt
    22981 actgatttat aattcacttc aattccaaaa tgcaggagaa agaacaaaat acgtgctttt
    23041 ctatgtgaca gctatgtcag tcagcatagt gctgatgaaa tttttccaat tattccaaac
    23101 ggaacaagct acttatatcc cgctgtttta tcccgctgct tttgcaccac ttgttttaag
    23161 ctttttcttg aaccgaagag cagggatcat ggctggtatt ttccaagcag tatctgcact
    23221 tttcattttt tatgattcga ttggcacgaa ctttctaacg attatcttga tgtcttatgt
    23281 tttctctggg ctcatggcaa cgattgtcag acgcaaacgg atctcagaac aaggattatc
    23341 tgctgccatg tgggtcatta tttttcctgt gatgatggat gtcattttga tcgtctatca
    23401 aggaatgagc tttggtgatg caacgacttg gttaatgctt gtctgcgggt tcactggtgc
    23461 actcttctca ttcttgctga cgatcggtct acacccatat attgaattga tggtcaatga
    23521 tgacagtgta attgtattaa atgaactcag caatccaaat catcctttat tgaaacagtt
    23581 gctggaagaa gcgccaggta cttatcatca tagtatgatg gtagctaatc taagtgctaa
    23641 cgctgtagca gaaatcggcg gacgttcttt gctaactcga gtagcttgct attatcatga
    23701 tatcggcaag atcaaacatg ctagcttttt cgttgagaac ttgccttcag gagcggaaaa
    23761 cccgcacaat ttcttattgc cagaagacag taaacatatt atctttggac atgtgacaga
    23821 tggagccaaa atattggaag attataatat gccgcaaatg gtgatcgata tttgcaaaca
    23881 gcatcatgga accacgctaa tgcgttattt ctacatcaaa gcgaaagaac gcaatccgga
    23941 agtaacagaa gagcaattcc gttatcctgg accaaaaccg caaagtcgtg aagcagggat
    24001 cgtcaatatt gctgacagtt gtgaggctgc agtacgggca atggatcatc cgacgagcga
    24061 aaaaatcgaa agttttgtcc ataatcttat cgaagagcgt atttccgatg gtcaattaga
    24121 cgatagtgga ctgaccttga aagaaatccg aaaagtggaa aaatcattga tcagcggttt
    24181 aagtagcacc ttccattctc ggatcaaata tcctaaaatg aaaacagaag ttgagaagat
    24241 aaaggaagaa caagaagaat agaaagaagc gatgtataat ggatattacc tttatggatg
    24301 aaacaaacca agtctcagaa gagaaaatga aagaaatcga tgacttgctg caatttgcag
    24361 catcttattt aaagctgcca gaggaaacag aaatgtctgt tactttcatg gacaatgcgg
    24421 caatccaagt aatcaatcgt gattaccgtg gaaaagatgc accgacagac gtcatcagtt
    24481 ttgctctgga agaagaaggc gaagacgaaa tcccagtgat ttttgaagat ggagagaatc
    24541 ctttgcctcg tgtactagga gacatcatga tttctattga acgtgctgct gaacaagcag
    24601 aagcttacgg ccattcatat gatcgggaac ttggcttttt agcggtacat ggattcttgc
    24661 atatcaacgg gtatgaccat atgacaccag aagatgagaa agaaatgttt ggtttacaga
    24721 aagagatctt ggatgcctat ggactcaaaa gataaaaacg tagagaaaaa caaacatttc
    24781 ctgatgtctg tggaatttgc tgtccaagga gtcaaaaccg tttttgagga agaacgcaat
    24841 atgaggaaac atgttgcgtt cggtatcctt gctttattta tgggcgtgat tttccagctt
    24901 gatcggatag agtggttatg gctgctttta gctgtttttc tcgtttggat agtagagatc
    24961 atcaatactg tttttgaaaa tgtagtggac atgtttacgg attttcattt tcatccgatt
    25021 gggaaaaaaa tcaaagatat ggcagctgga gcagttttag tgaccgcttg ttttgctgtc
    25081 atcattgggt tgattttatt tgtccctaaa atatatcatt tgttgtttaa ttaaaaagga
    25141 gaacgtatat gccagaacat aaatcagggt ttgtcgcaat cgtcggccgc ccgaatgtag
    25201 gaaaatccac attattgaac cgaatcgtgg gtcaaaaaat tgccattatg agtgacaagg
    25261 cacagacaac tagaaataaa atccaaggag tatatactac accagaagct cagctgattt
    25321 ttatcgatac accaggaatc cataaaccaa agcatcgtct aggagatttt atggtagaag
    25381 cagcttacag tgcgttgaaa gaagtggatg cagtcttatt tatgatcagt gctgatcaaa
    25441 aacgcggccg gggagacgat tttattattg aacgtctaaa aaacgtgcat tctccagttt
    25501 atctgattat caataaaatc gataagatcc atccagacga gttgctggga atcatcgaag
    25561 attattcgac gcagatgcct tttgcacaag tgattccgat ctctgctaca gaaggaaaca
    25621 atgtcgaacg cttaatggat gtattagtca gtgaaatgcc agagggccca caatattttc
    25681 cagatgatca agtgactgat catcctgaat actttatcgt ttctgaattg atccgtgaga
    25741 aagtcttgtt tttaacacga gacgaagtgc ctcattctgt cgcagtcgtt gttgattcga
    25801 tgaagcgaaa cgagaatgat aaaatccata tccaggccac gatcatcgtc gaaagagata
    25861 gccaaaaagg aatcattatc ggcaaaggcg gaaaaatgct gaagcaagta ggaacgaaag
    25921 caagaaagga tatcgaaaat cttttaggag acaaagtatt tctagaactt tgggtcaaag
    25981 tccaaaaaga ctggcgagac aaaaaagtct atctgcaaga ctttggctac cgaaaagacg
    26041 aatactgata ttctgaactt cttataggtt aagtatagaa ataaactgga taaaaatccg
    26101 cacgttgaga aaaacggcgg aagatcgaaa cataaataat ctggatcggc agaatctgct
    26161 tttccagatt tattttttag gagggagaat atgagccagc ttgcagaatc gaaaggcttg
    26221 attttatcta gccgtaatta caaagaaaaa gataaattag tcaaaatctt tacggaatct
    26281 tctggcaaaa tgatgtttta tatcaaagga atccatcggc aaaatcagcc attagctccg
    26341 gctttgctcc cctttaccga agcagtctat atcggtaatt ttcgaagtga aggtttgtcg
    26401 tttttaagca gtgtcaaaga cgtccatgcg tttcggaaca tccaagaaga tatctttttg
    26461 agcggttatg gtacctattt gctaaatcta gtagatgcag caatcgaaga tcatcaatat
    26521 gacccgcatt tattccaatt tacgcaacaa gctctgcagc ggatggatca aggagatgat
    26581 gcagaaatca tcacgaatat ctttgaagtt caaatactgc aacgcttcgg aatcgcgcca
    26641 atttggacgc actgtgtcgt atgcggggaa acaaaaggaa aatttgacta ttcttccaaa
    26701 tctggcggtg tgatatgcga gaaacactgg ccaatggacg aacaccgtta tcatgcagat
    26761 cctcgcgctg tttatttcgt tcgaatgttt tcggctattt cttatgataa gatcagtgga
    26821 atccacttga aagaagaaac gaagcaggca atccgtgacc tcattgacca gttgtatgat
    26881 gaatatgtcg gtattcatct aaaaagcaaa aagttcattg atcaaatgaa gtcttgggca
    26941 cacgtattaa agacgccaga gaaaaatatg cctgaaaaag agatacctga aaaagaagaa
    27001 taaatgaaag atacaacaaa aaaatcaaaa ctatttgaca aatacaggga cttccgtcta
    27061 ttattaaccg tagattaaat agatcgttca ctgagaggat ctattatata aacaagaaaa
    27121 ctgcaaaatg aatacgtaca ttgaccaaga tcagtaaaaa acacgtggtt tagcgagttc
    27181 gggagagtgg aagccggacc caaacgattt ttgaagaggc acttgcgagt acgataaatg
    27241 aagctgccga atctttattc ggaagtaggg tggaaccgcg aaattattcg tccctatgtc
    27301 tgtaatcaga catagggact ttttgtcgtt ttctttcctg tattcttatt gacagcaacg
    27361 cttaaaaatt gaaaggggca aaacagatga gtaaaaaatt gaccgtccaa gatatgattt
    27421 taacattaca aaaattttgg tcatcaaacg gctgcatgct gatgcaagct tatgacacag
    27481 aaaaaggagc aggtacgatg agcccatata cattcttacg ggcaatcgga ccggaaccat
    27541 ggaatgctgc ttatgtagag ccatcccgcc gaccagctga cgggcgttat ggagaaaacc
    27601 caaaccgttt gtatcagcat catcaatttc aagtcgtaat gaaaccttca cctgaaaata
    27661 tccaagagct ttatttagaa agcttgcgtc ttttaggaat tgatccatta gaacacgata
    27721 ttcgttttgt tgaagacaac tgggagaacc catcgatggg gtgtgccggt gtgggttggg
    27781 aagtatggct tgatgggatg gagatcacac aattcacgta cttccagcaa gtcggaggac
    27841 taccttgtaa accagttact tctgagatca cttatggact agaacgtctt gcttcatata
    27901 ttcaagaagt tgaaagtgtc tatgatctgg aatgggctga tggtgtgaaa tatggcgaga
    27961 tcttcaaaca accagaatat gaacattcca aatattcttt tgaagtaagt gaccaagact
    28021 tgctactaag caactttgac cgttttgaaa aagaagctaa acgctgtatc gatgaaaatc
    28081 ttgttcatcc agcgtatgat tatattttga aatgcagcca tacattcaat ttattagatg
    28141 ctcgcggtgc agtatccgta acagaacgag caggttatct ttcccgtatc cgcaacatgg
    28201 ctcgtgctgt agccaaaatc tttgtggcag aacgcgaaaa attaggattc cctttattga
    28261 ataaaaacac agcaaatcca gaaaacatga aggaggctga ataagatggc aaaagactta
    28321 ttacttgaaa tcgggctgga agaaatgcct gctcatgttg tcacaccaag catgaaacaa
    28381 ttagaagaaa aaacagcaaa atttttagat gaaaaccaat tgacttatga tacgatcgaa
    28441 acgttttcta caccgcgccg cttagcaatc aaagtaacaa acattccaga acgtcaagca
    28501 gacagcgaag aagaagtcaa aggaccagcc aaaaaaattg ctttggacgc agatggaaac
    28561 tggacgaaag cagctgaagg atttgtccgc ggacaaggtc tgacgacaga tgctatcact
    28621 tttagagaat taaaaggcgt ggaatatgtc tatgtaacga aatacactca cggcaaagaa
    28681 gcaaaagaag tattgacagg tttagcagat gtcattaaaa gcctcacttt cccagtaacg
    28741 atgcactggg cagaatacga ttttgaatat attcgcccta ttcactggat cgtggcattg
    28801 ttagatgacg aaataatccc gtttgagatc ttggatgtca aaacagacag agcttcaaga
    28861 ggtcatcgtt tcttaggcga agatgtgaca tttacgcatg caaaagaata cgaagaaaaa
    28921 ttgaatgaac aatttgttat tgcttcaccg caaaaaagaa aagaaatgat catcacacaa
    28981 gcaaacgaat tagccgaaaa aaatcactgg atcattgatc tagatgaaga tttactagaa
    29041 gaagtcaaca atttagtcga atatccaact gtcttttctg gcgacttcga agaaaaatat
    29101 ctatctgttc ctgaagaagt actagtcact tctatgaaag aacatcaacg ttatttcgaa
    29161 gtacggaacg atcaaggtat gttgcttcct cattttattt ctgctcgtaa tggcgatcgg
    29221 gtaaaattgg aaaatgtggt acgaggcaat caaaaagtat tgacggctcg tttagaagat
    29281 gcggaattct tttataatga agacaagaaa gcttcaatcg accaatacgt tgaaaaatta
    29341 aaaactgtta ctttccatga aaaaatcggt agcatctatg agaaaatgca acgggtacaa
    29401 gtcatcgctc gcatcatagg cgaacaagta ggactatctg aggaagaatt gatggatctg
    29461 caacgcgctg ctgaaatcta taaatttgat ctagtaacca acatggtagg agaattccct
    29521 gaactacaag ggatcatggg agaaaaatat gctctgctga aaggcgagaa accagccgta
    29581 gcaacagcga tccgtgaaca ttacatgcct atatccagtg aaggagattt acctgagact
    29641 acagtaggtt ctgttttagc gattgctgat aaattagata gtatcttttc tttctttgca
    29701 gttgggatga tcccaagtgg ctcaaacgat ccatatgctt tgcgccgtca agcatatggt
    29761 gtcgttcgaa tcatcgaatc gaaaaaatgg gcctttcctt tgtctgttct gcaagaaacg
    29821 attagtgaag ttatcagtaa agatacggat cgttttggca ttggcttgtc agcgggacaa
    29881 caacaggtga tcgactttat caaaggccgt ctgcgccaat tattgacaac gaagaatatc
    29941 cgtcatgatg tcatcgaagc tgttttgaat gcagaacaaa aagatctgac aaaagtattt
    30001 gcagcagcac aattgttcaa gcagcatctt gcagatgaag acttcaaacc atcgatggaa
    30061 gctttgacac gtgtcgtgaa cttagcgaaa aaagcggagc ttgaaaaaca atcagaagta
    30121 gaccctgaac tgttcgaaaa cgaagcggag aaagaactgc acaaagcagt agaggcaatg
    30181 aaaacaagct ttgctgacca aacgatcaac gaaaattatg atcagcttgt aagccttcgc
    30241 ccactgatcg aaaattattt tgatcagacg atggtcatgg cagaagaacc agcagtacgt
    30301 aagaaccgat taacgcaatt aagtcaaatt gctgccatgg ctttgtcact agcaagttta
    30361 gatcaaatca tcacaaaata atttctaata tgtaaataaa ccagagaaca ggcacaaaat
    30421 aggctatttc tctggtttat ttgttataaa tataaataac tattattaat tcaatgttaa
    30481 tttttttgtt attttatttt ttgtgtaact tttaaaaaca cctatgaaaa ttaaggaaat
    30541 aaaaatgaaa tcgattaatt gttatcttat taatgtttta tttactttta aatcgtaaat
    30601 tgccctagtc aagaaaatag tttgtggtat gattatatag ggaaaacttg tttacaaata
    30661 tttctgtgaa tatattaatt taattatgtt ttttaaaata aaaagctgtc atttttatgt
    30721 atgtgaatta tatcttaatt tatctatcat caatacttag gagtgaatct atggaaaagc
    30781 cattcgtcaa gtcattgact gctgtggcgg taggtgcagg tgctattgcg atctgtttgt
    30841 ttggttacca tatcaataat cagcggcaac atcagcaacg gatcaattat gcagaatctg
    30901 ccatcaccaa tcaaaaagac accttgactt ctttatcaaa agaagtagac aagctgtata
    30961 gtacaaaaga aaaaaatttt ctaaaccctg aaataacaga agaaacaatc acaagtttgt
    31021 caaataagct atcctctgtc aaactttcag cagatgatta cgacatcaaa gaatcagaat
    31081 tgcctaaaga agctgttgca atccaagatg agaagaaagc aatcgtgaca cagttagata
    31141 gtgcagaatc aaaactgaag atccagacag ctgtcaacga tttatttact aaaaatgtat
    31201 caaactggca gcaagctgta gacgatgtcg tcatcaaaga aaaggtgaca agtgcagatg
    31261 tcgctcgtgt acgtgaaaat atgagctttt ttaaagatag tccttggaaa acggttgtta
    31321 tgcaatatct aggattcgct gatactcaga tcgcgcaagt cacgcaacta gatcagttat
    31381 tcgatacgat gttgaaggat ggtcaagtga ctgccaccgc tacttacgat caatatttga
    31441 cggcgctcag tcaaatagag cagatccgga atgaaaaaat aagcgcagca tacgcaacaa
    31501 aagcacaaac tgttgctcag caaatgggct atagcaatat aagttattga cagttaaaac
    31561 gttgattcaa gcaaggttag caaacggagg aaactatggc aagacgaaga agaaaatcaa
    31621 gagggaaaaa aatatttctg attattttag cagttcttat cgtattagta ttagcaattg
    31681 taggagtagg agcaaaatta tatctggatc tctcacattc tattgagaaa acttacgaat
    31741 cagtggaacg aacccaagga gaacgaacga aaccagttga tctggacaaa caagaatctt
    31801 tctctgttct attgatgggc attgatactg gagatttagg tcgggtcgat caaggaagat
    31861 cagatacgat gatggttgcc acagtcagtc ctgaagacaa acagacaacg atcgtcagca
    31921 ttcctcgaga tacgtatgtc gacatcgtag gtcgtgacac aaaagacaag atcaaccacg
    31981 cttacgcatt cggcggagct gccatggcga tggataccct acaaaaatat gtagacatcc
    32041 caatcgatca ctatgtctct atcaatatga aagggctaaa ggaactcgtt gatgcagttg
    32101 gtggtatcga agtcaataat gacctcactt tctcacaaga tggctatgac tttccaatcg
    32161 gtaaaattac attgaacggg gatcaggcat tatcttattc tcgtatgcgt tatgaagatc
    32221 caaatggtga ctatggtaga caagagcgtc aaagaaagat cgtagaaggt gtagcaaaaa
    32281 aagtattgag tttaaacggt gtcagcaact atcaatccgt tttgaatgct ctagagtcga
    32341 atatgaaaac agacatgagc tttgatgaaa tgaaaaaaat cgctttagat tatcgggagg
    32401 catttggtac gatcaagcaa gatcagctgc aaggagaagg cttcatgcaa gataatatct
    32461 cctatcaaaa agtcagcgat caagaacttg atcgtgtgaa aaaagaatta aaagatcaaa
    32521 tgaatctaga gaataaatag gaaagtggag aaaaaatgga agagacaatc agcttgaaag
    32581 aaatttttga aacattacgc aaacacttgg taacaatcat catctcaatg tttgctggct
    32641 tggccatctc aggaatcgta acatttttca tcttgacacc aaaatacagt tcacaagcac
    32701 aattgatcgt gacactgcca caatcagaca cagcaaatgt caatgatgtc aatacgaacc
    32761 tgcaaatgat caatacgtat aaagatatga tcgtcagtga tttagtacta aatgaagtca
    32821 aagatcgttt agaaacagaa gacaatgtga aaatgactgc tggacaaatc aaagatgcga
    32881 tctccgtcaa tcagtcacaa aattcacaaa tgttctcgat ccaggcaata agcacgaatg
    32941 cagtgactgc tcaacagatc gctaacacaa cttcacaagt tttccaagag aacgcaaaag
    33001 acgtgatgaa tgtcgataaa atctcgatta tttcaggtgc agttgccaat acgacacctg
    33061 tttcgccaaa taataaattg aatctagtga ttggcttagt attaggaatg atggtaggcg
    33121 taggtctggc attcttattc gaattacttg atcggacagt gaaagatgaa aaatatgtga
    33181 cggatgcatt aggattccca atcttaggaa cagttccaga aatgtcagcg aaagaattga
    33241 acgctggtat ccgtaaaaaa ggaacagctc ctgcacgacc aaaagctaca aacgataaaa
    33301 cagccccatc acgcagaagc cgctcaagag tctaggagga agaaaaatgg cacgaacaca
    33361 gaaacaaaaa gcagcacaaa ctcatgcagt cagtttgatc acattaacaa acccatcttc
    33421 accaatcgcc gaacaatatc gtacgatccg gacgaatatc cagtttgcct ccgcagctgg
    33481 tcagcaaatc aaaacgattg tcgtgacttc atcaggtcct ggagaaggaa aatccaccac
    33541 tgcagcaaac attgcagtcg tttttgctaa atccggtcaa cgagttctac tagtcgatgc
    33601 agatttacgt aaacccgtcg tctataagac attccagctg aacaatgcca ggggattaag
    33661 tacagcactt agttcatcag gaagtgtagc agatgtaatc caacgaacgc cagtcgagaa
    33721 cttgtcgatt ttgcctagtg gacctaagcc acccaaccca tcagaattgt taagttcgcc
    33781 aagaatggat cagatcctag acgaagcaag acagttattt gacgtggtga tattcgatat
    33841 gccaccagta gtagccgtaa cagatgcaca gatcatgtct tcaaaaacgg atggcacttt
    33901 attggtcgta cgtgaaaata catcacgtaa agaatcattg aataaagcaa aagaactgct
    33961 agagatggta caagcacgag ttttaggtgt tgtatacaac ggagcagaac atagcaaaga
    34021 tgctggttat tactacggaa attaaggaat aagaagagag gagacaagag aaatgatcga
    34081 tctacattgc catatcctac caggaatcga tgacggggca gaaaacttag aagcaagtat
    34141 tgcaatggct gaaaaagcga ttcagcaagg catcacgcat attttatgca caccacacca
    34201 caataatgga aaatacagca atgaaaaatc acaagtcatt tctctagtcg cttcgttaca
    34261 agccgaatta gagaaaagac agttgccttt gacgttattg gaaggacaag aagtacgtat
    34321 taccggaacg ctcatcgaag acatccaccg agatgaaatt ttatttacag atttagatga
    34381 tacatatctt ctgatcgaat ttccgacact ggaagtgccg ttatatgcag aacggctttt
    34441 ttttgagttg ttagaactag gaaagacacc agtgatcgtc catccagaac gcaacgcgca
    34501 ttttcgcgaa gacccgaatc atttgcttcc gttcctagat atggggtgtt tggcccaact
    34561 tactgcgcca agttatgttg gggtatttgg caaagatatt cagaaaacag ctaaaacaat
    34621 ggtcaaacat aatctcgtgc agatgactgc ttctgatgca cacggagtct ctaagcgcac
    34681 cttttactta aaagagtgct atgagcagat tgccaaggac tttggtaagg aaaaagtagt
    34741 acagatgaag caagttgcaa aggatctgat caacggggat gaaatcagtt atccagacta
    34801 tgaagaggta aaaaagaaga agtttggttt attttagggg gaattaaaaa gtgtttatat
    34861 taacaagaag aagaaaaatt gccacattgg tttttgtgga cagcttgtta ttaattgctg
    34921 caaatattgc agcagctaaa ttcatgaagc cgtttgtatc tataccaatg gatcttattt
    34981 taatctctat cggtttgtcg attggttttt atttatttta tggtagttta ttcaaagttt
    35041 tcactcggat caatcgctat acaaatttaa gagagatcat tgcaattttt agttcactat
    35101 ctgcaagtgc tgcctcaagt atcctcatac tgctgttcat taatcggcga tacagtttac
    35161 ggttagttat ctttgcttat ctgctttcgc tcttattgat catcggtagc cgattgatct
    35221 ggcgtatcta catcgaaaca aaaaatatga gatacgtatc agcagattct gctaaaaata
    35281 cattgattgt tggtgctggc gaaggcgggc gtattttata caacagcttt cttggatcca
    35341 aaacggctca agatatccac gttgtcgggt ttgtagatga tgatccaaat aaaagaaata
    35401 cgtatctttc aggaaaaaaa gtattaggtg cattaaaaga tattccggaa ttgattgaaa
    35461 aatatgacat tcaaatggta acgatcgcta tcccttcctt atcaagaaaa aaattacgac
    35521 gaatcttcga gttagtcgaa tccgctcgtg tgaaagtcaa cacgatgcct tctatagaag
    35581 aacttgcttc agggaaaatt agcgtatcaa aattaaaaac aattgacgta gtggatttac
    35641 tgggaagaga tgaggtaaag ctggatattg aatccatcaa agatcagatc acagacaaag
    35701 tcattcttgt caccggcgca ggaggatcga tcggttcaga aatctgtcgg caaatcattc
    35761 aattcaatcc tgcaaagcta ttgcttttag gacatgggga gaactcgatc tacttgattg
    35821 accgtgagtt acgcacgcat catcaaaatt gtcctacaga aatcgtaccg atcatcgcag
    35881 atatccaaga tcgcgagaaa atcaatgaga tcatggaaca atatcatcca gatatcgtct
    35941 accatgcagc tgctcataaa catgtaccac tgatggaata taatccaaaa gaagcagtca
    36001 aaaacaatat tttcggtaca aaaaatgtag cagaagcagc taaagcagca aaagtgaaaa
    36061 acttcgtcat ggtatcgaca gataaagcta acaatcctcc aaatgtcatg ggttcaacaa
    36121 aacgaatcgc tgaaatgatt gtgactggat tgaatgaaga aggctgtacg aaattctcag
    36181 ctgtcagatt tgggaatgtc cttggttctc gcggtagtgt gattccagta ttcagagaac
    36241 aaattgctca aggtggtcca atcactgtaa cagactttcg tatgactcga tactttatga
    36301 cgattcctga agctagtcgt ttagttattc aatctggcgc attagcaaaa ggtggcgaaa
    36361 tttttattct agatatgagt gaaccagtga agattgtaga cctagcgaaa aacatgatcc
    36421 gattgagcgg gtatagcgaa gacgaaatcg aaatcattga aacaggtatc cgtccagggg
    36481 aaaaactata tgaagaacta ttgttggata aggaaagaaa tgatgaagca gtttatgaga
    36541 aaatctttgt aggaaacatc aaaggttact caatacaaaa agtgatggat tttgtcaaga
    36601 gcctgccgca agacgatgaa caattggcta aagacattgt cacttttgca aatgcttcga
    36661 atagatagga gattaaaaat tgaatatttt aatattaagt tgtggacgtc gttgtgaact
    36721 agtgaatgca tttaaaacag cattaaacaa taatgaaatg gaaggaaaaa tcattggagc
    36781 agattgctct gaactagcac ccgcactata tatgtgtgac gaaaaaatag tattacctaa
    36841 agtttcagaa agtaattata ttgaggaatt aataaaagta ataaagtttt ttgaaattaa
    36901 attaattgtt cctactattg atactgaatt atcaacatta tcaagaaata aaaaatatat
    36961 tgaaaatgaa acagactcag ttgtattagt ttcttcagaa aaagtcatcg acatttgtga
    37021 gaacaaaatt ttaacttctg ctttttttga acaaaatggt tttaaaactc ctgaaatttt
    37081 aaactcttct gaaattacaa aatttcctgt atttataaaa cctctgaatg gtagttcatc
    37141 tgttaacaca tttattgtaa ataatgaaaa agaattgttg ttttttagtg aatatataga
    37201 taatcctctt attcaagagt atattttagg tgaagaatat actatagatg tttgcttaaa
    37261 ctttgattcg acaccagtaa gtattgttcc tagaaaaaga atagcaacta gaggtgggga
    37321 aatactgaag ggtcagatta ttaaagatag agaactaatt gagactacga aaaagatgtt
    37381 ggaaaaatta aatgcaatcg gacatattac tattcaatgt ataaaaaacg aaaagggaat
    37441 attttattta gaaataaatg caagatacgg tggaggagcc cccattagca ttaaatcagg
    37501 agctaattcc cctgaatata ttataaagat gatagattca aaaaaaaatt tgagatacag
    37561 agaaaattat ttagataaaa tgatagcact gagatatgat caagcgattt atttagatga
    37621 aaaaggaaat gtatataatg attaaagcgg tgatctttga tttagatgac actcttgtgt
    37681 ctgaatatga ttatgtaaaa agtggataca aatgtgtagc tagaagatta gcagtgcaaa
    37741 aaattttccc ggctactttt gacgaaatat atagagtcct tttagatctt tttgctgaag
    37801 atagtaaaaa tgtatttaat cgtctatatg actattttga aattccttat agtaaaaaag
    37861 aaattaaaga actggtaaat gtatatcgag aacacaaacc agacataaat tttttagaaa
    37921 atgcagatac tttattaacg gaattaagaa gtagaggata caagctgggg attattacag
    37981 atgggtatgc tataacccaa cgaaacaaat tggatgcttt gaaagtagac tatttggtag
    38041 attatatttg tattactgac gaattaggcc gtgaattgtg gaaaccacac cctatctcat
    38101 atcttttatt gttagaaaag tttaatttaa aggcacaaga gtgtatatat attggcgata
    38161 atgagttgaa agattttata actgccaaat caataggaat gcaaacaatt aaaatagaaa
    38221 gagtaaatgg tatttacaga gaaagcagtt tgaagttcaa aagattttac caagctgata
    38281 aaaaaatacg ttcgttatgg gagataaaaa attttttggg agtgatttca tgaaaagtaa
    38341 aagaattcta ttagcttctc cacatatgag tgaagaagga tatgaaaaag agtatgtaaa
    38401 agaagcattt gatacaaatt gggttgctcc tttaggtgcg aatgtgaatg gatttgagaa
    38461 agaattagca gaatacgtgg gagctagtca tgctgccgca ttatcttctg gaacagcagc
    38521 tatacattta gctttgaaag cggctggggt cggtaaagat gacatagtga tttgtcagtc
    38581 cttgacgttc tcagctactg ctaatccaat tctctatcaa ggagctatac ctgtatttgt
    38641 tgatagtgat tacgaaactt ggaatatgaa acctgaacat ttgcgaacag cactagaaaa
    38701 atatcctaac acaaaggctg tattagtagt acatttgtac ggtttatcag ctaatttaga
    38761 cgaaattact aaaatatgca aagaatacga tgttactcta attgaagatg ctgcagaatc
    38821 attaggaaca acatataaag gaaaatatac tggtacattt ggcgactatg gaatttattc
    38881 ttttaatgga aataagataa tcacaacttc aggtggcgga atgcttgtat ccaatgacaa
    38941 agaaaaggtg gaaaaagtga gattttgggc tacgcaatct cgtgagaagg cacgccatta
    39001 tcaacacaat gaaattggct ataattatcg aatgagcaat atcgttgctg gtatcggtcg
    39061 aggacaattg aaagtattaa atgaaagaat tgagaaaaaa cgatatattc atagttttta
    39121 taaaaaagaa ttgtctaaat tgtcaaatat acaattcatg ccagaaaata attggaatga
    39181 accgaattat tggttaagtg tcataacaat aaagggaata aatgcgaatc atcttattga
    39241 tgagttagac aaaaataata tagaagcccg cccagtatgg aaacctatgc atttacaacc
    39301 tgtttttaaa aattatgatt atattggcga tgatgtagca gaaactttat ttgacttagg
    39361 agtatgttta ccatcagata caaagatgac agatgaagat ttaaaatatg tagtatctac
    39421 gattaaaaga gtgatcaatg atgcgtaaaa aaactttcta tcagcttttt gggaaaagaa
    39481 ttttagatat cctattgtca ggaattgctc tcatcgtttt atcgccgata atcttaattg
    39541 taggtttttt agtaagaatt aaacttggtt ctccaattat cttcaaacaa gaacgaccag
    39601 gaaaaagtga aaaaattttt tccatgtata aatttcgtac aatgactgac gaaagagacc
    39661 acaatggaga atatttacct gatgaaattc gactaactaa atttgggaaa atgcttagag
    39721 caacaagtct ggatgagcta cccgaacttt ggaatatttt gaaaggtgat atgtcgatcg
    39781 taggacctcg tccattatta gtggagtatt tgccactata tagtgagaag caacggaaaa
    39841 gacacaacgt aagaccagga ttaactggac tggctcaggt caatggaaga aatgctatta
    39901 gttgggaaga aaagtttgat ttagatgttt attatgttga taaaattagt ttctttaatg
    39961 atcttattat tataattcag acatgtaaaa aagtaatcaa gaaagagaat attaatacaa
    40021 tcaataacaa tatcccagaa aaatttaaag ggagttaaat acagcagctt aatgcaagtt
    40081 ttgtgacttg cattatattt aggtataaat caaagcgagt atattagaat tatataacat
    40141 atgttaaaaa aacgtatagc taataaaagt atgattttaa aaatttgtgt agagttttaa
    40201 atatactgtt tcaatacgag aaaattataa aaaagtataa ggaaaagaga gttatggcaa
    40261 agtattataa taaaaaaatt cttataatgg caaacaacga tgatggtctt taccgttttc
    40321 gaggaatgct cataaaaaac ttagtagatc aaggtaatga agttattgta tctcttccaa
    40381 agggcaagaa tattcctaaa ttaattgaac ttggatgtca aattattgaa actccaatag
    40441 atagaagagg aattaatcca aaaactgact ttaaactatt ttttaactat tgtaatattt
    40501 tgaaaaaaat aaagccagat atggtcattg cttatactat caaaccaaat atatacggtg
    40561 gattggcatg tcggttaaga aaggtttctt atgcattaaa tataaccgga ttaggaacgg
    40621 catttcaaaa aaagggggtt ttgaaaagtc ttattgtatt tttgtataga ttagcagcta
    40681 aaaaatctaa ggtcatattt ttcgaaaatt ttgaaaatat gaaaacattt cagactttac
    40741 aaattgctaa acaaagtaaa tacaagctat taaacggtgc aggagtagat gtagaacact
    40801 ttagttattt agaatatcct aaagatgagc aagttcattt tttatttatt ggaagaatta
    40861 tgaaagagaa aggtgtagat gaactttttg aagcaatgaa aaacttatat agtgaagaga
    40921 aaaattgtgt acttgatgtc cttgggtatt ttgaagaaga ttacggcata aaaattgaaa
    40981 aatacgaaaa agagggatgg ttaaaatatc atggatatca atctgatatt cgtccctttg
    41041 tagaaagagc acattgcttt gttttgccta gttggcacga aggaatggca aatactaacc
    41101 ttgaatcagc agcatcaggg agaccaatta ttacaagtga tatcccaggg tgtaaagaag
    41161 cagttattga atcgaagtct ggttatttat gtgaaagaaa aaatagttgt agtctctata
    41221 attcgatgaa taaatttcta aaattatcat atgagcagcg cattaacatg
//
LOCUS       DADGHT010000011        39887 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.011, whole genome shotgun sequence.
ACCESSION   DADGHT010000011 DADGHT010000000
VERSION     DADGHT010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.011"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            73..942
                     /locus_tag="JX887_000523"
     CDS             73..942
                     /locus_tag="JX887_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAX1256536.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            1107..2378
                     /locus_tag="JX887_000524"
     CDS             1107..2378
                     /locus_tag="JX887_000524"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAX1256537.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            2375..3670
                     /locus_tag="JX887_000525"
     CDS             2375..3670
                     /locus_tag="JX887_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAX1256538.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            3769..4032
                     /locus_tag="JX887_000526"
     CDS             3769..4032
                     /locus_tag="JX887_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAX1256539.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            4477..4926
                     /locus_tag="JX887_000527"
     CDS             4477..4926
                     /locus_tag="JX887_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1256540.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            4983..6401
                     /locus_tag="JX887_000528"
     CDS             4983..6401
                     /locus_tag="JX887_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1256541.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            6401..7261
                     /locus_tag="JX887_000529"
     CDS             6401..7261
                     /locus_tag="JX887_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAX1256542.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            7435..8208
                     /locus_tag="JX887_000530"
     CDS             7435..8208
                     /locus_tag="JX887_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAX1256543.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            8355..8720
                     /locus_tag="JX887_000531"
     CDS             8355..8720
                     /locus_tag="JX887_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAX1256544.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(8868..10076)
                     /locus_tag="JX887_000532"
     CDS             complement(8868..10076)
                     /locus_tag="JX887_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1256545.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(10095..10373)
                     /locus_tag="JX887_000533"
     CDS             complement(10095..10373)
                     /locus_tag="JX887_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256546.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            10566..11222
                     /locus_tag="JX887_000534"
     CDS             10566..11222
                     /locus_tag="JX887_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAX1256547.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(11664..12461)
                     /locus_tag="JX887_000535"
     CDS             complement(11664..12461)
                     /locus_tag="JX887_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAX1256548.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(12458..13642)
                     /locus_tag="JX887_000536"
     CDS             complement(12458..13642)
                     /locus_tag="JX887_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAX1256549.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(13667..14914)
                     /locus_tag="JX887_000537"
     CDS             complement(13667..14914)
                     /locus_tag="JX887_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAX1256550.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            15129..16874
                     /gene="dnaX"
                     /locus_tag="JX887_000538"
     CDS             15129..16874
                     /gene="dnaX"
                     /locus_tag="JX887_000538"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAX1256551.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            16894..17208
                     /locus_tag="JX887_000539"
     CDS             16894..17208
                     /locus_tag="JX887_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAX1256552.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            17233..17829
                     /gene="recR"
                     /locus_tag="JX887_000540"
     CDS             17233..17829
                     /gene="recR"
                     /locus_tag="JX887_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAX1256553.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            17893..18537
                     /locus_tag="JX887_000541"
     CDS             17893..18537
                     /locus_tag="JX887_000541"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAX1256554.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            18552..18881
                     /locus_tag="JX887_000542"
     CDS             18552..18881
                     /locus_tag="JX887_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256555.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            18895..19833
                     /gene="holB"
                     /locus_tag="JX887_000543"
     CDS             18895..19833
                     /gene="holB"
                     /locus_tag="JX887_000543"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAX1256556.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            19869..20693
                     /locus_tag="JX887_000544"
     CDS             19869..20693
                     /locus_tag="JX887_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAX1256557.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            20686..21033
                     /locus_tag="JX887_000545"
     CDS             20686..21033
                     /locus_tag="JX887_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAX1256558.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            21102..21974
                     /gene="rsmI"
                     /locus_tag="JX887_000546"
     CDS             21102..21974
                     /gene="rsmI"
                     /locus_tag="JX887_000546"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAX1256559.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            22083..23204
                     /gene="dinB"
                     /locus_tag="JX887_000547"
     CDS             22083..23204
                     /gene="dinB"
                     /locus_tag="JX887_000547"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAX1256560.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(23258..23860)
                     /gene="nrdG"
                     /locus_tag="JX887_000548"
     CDS             complement(23258..23860)
                     /gene="nrdG"
                     /locus_tag="JX887_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAX1256561.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(24175..26364)
                     /gene="nrdD"
                     /locus_tag="JX887_000549"
     CDS             complement(24175..26364)
                     /gene="nrdD"
                     /locus_tag="JX887_000549"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAX1256562.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            26690..27457
                     /locus_tag="JX887_000550"
     CDS             26690..27457
                     /locus_tag="JX887_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256563.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            27447..29489
                     /locus_tag="JX887_000551"
     CDS             27447..29489
                     /locus_tag="JX887_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1256564.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            29770..29919
                     /locus_tag="JX887_000552"
     CDS             29770..29919
                     /locus_tag="JX887_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAX1256565.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            29930..31444
                     /gene="dltA"
                     /locus_tag="JX887_000553"
     CDS             29930..31444
                     /gene="dltA"
                     /locus_tag="JX887_000553"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAX1256566.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            31441..32646
                     /gene="dltB"
                     /locus_tag="JX887_000554"
     CDS             31441..32646
                     /gene="dltB"
                     /locus_tag="JX887_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAX1256567.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            32691..32924
                     /gene="dltC"
                     /locus_tag="JX887_000555"
     CDS             32691..32924
                     /gene="dltC"
                     /locus_tag="JX887_000555"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAX1256568.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            32927..34195
                     /gene="dltD"
                     /locus_tag="JX887_000556"
     CDS             32927..34195
                     /gene="dltD"
                     /locus_tag="JX887_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAX1256569.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            34336..35418
                     /locus_tag="JX887_000557"
     CDS             34336..35418
                     /locus_tag="JX887_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAX1256570.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            35418..36221
                     /locus_tag="JX887_000558"
     CDS             35418..36221
                     /locus_tag="JX887_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAX1256571.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            36291..37031
                     /locus_tag="JX887_000559"
     CDS             36291..37031
                     /locus_tag="JX887_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAX1256572.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            37042..38046
                     /locus_tag="JX887_000560"
     CDS             37042..38046
                     /locus_tag="JX887_000560"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAX1256573.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(38091..39854)
                     /locus_tag="JX887_000561"
     CDS             complement(38091..39854)
                     /locus_tag="JX887_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256574.1"
                     /translation="MLFLTGIAYFFYFIFSPADSNQMKEIKDSWVFYTKDDPDFKFDS
                     KYTRTIPTVDKDETFIMETTLEKPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEES
                     NPGLSLAVIDLPANYIGKKLTLTVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQV
                     LTMIIAVFIAIGTFFYTIYLMYKQKRLEYSLILLSCFALALGFEAVSEDILSGILFEP
                     FVHSFLSHLFIILTSAFIICYYWSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAEL
                     PELMPIANIASVISTLVTSLACIGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGI
                     YQTTINWSTILYIIILIVIISYNLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQH
                     IQEVNTLRLEFVQEMENLQDLMHTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLI
                     LARYQKLAAKRNIQITFQADLPEELPINDDDLAQLLIHALEHSFRETHAIENPLYRKI
                     YLSIHEQEEHFVICCEHSAHYDTNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQ
                     EKDTFIDRITVQLSRNYPNPV"
BASE COUNT        12792 a         7022 c         8279 g        11794 t
ORIGIN      
        1 ggtaaaatag ggtcgttggt taagaattgt cttaacaaat ttagttttac aaaacttagg
       61 aggaatttta ttatgccagt agtatcagga gctgaatttt taaaagctgc tcgtaaaggc
      121 ggttacgctg tcggcggatt caacacaaac aacttggaat ggactcaagc aatccttgaa
      181 gcggctgaag caaaacaagc accagtactt atccaaacat caatgggtgc agctaaatac
      241 atgggtggtt acaaaatctg taaagattta atcactgatt tagttgaagc aatgaacatc
      301 actgttccag ttgctatcca cttagaccat ggtgattacg aagctgcttt ggaatgtatc
      361 gaattaggct atacttcagt aatgttcgat ggttcacatc taccatttga agaaaacttg
      421 aaattagcta aagacgttgt tgaaaaagca catgcaaaag gtatctcagt tgaatgtgaa
      481 gttggttcaa tcggcggaga agaagacgga atcatcggta acggcgaatt agctgatatt
      541 gaagaatgca aacaaatggt tgctacaggt atcgactact tagcttgcgg tatcggtaac
      601 atccatggtc aatatccaga aaactggaaa ggattagctt ttgaccactt acaagcaatt
      661 gctgatgctg taggtccaga catgccttta gtattacatg gcggatcagg tattcctcaa
      721 gatcaaatcg aaaaagctat ctcaatgggt atctcaaaag taaatgttaa cactgaattc
      781 caattatcat ttgctgcagc tactcgtaaa tatatcgaag ctggtaaaga taaagaaggt
      841 aaaggattcg accctcgtaa attattagct ccaggtaaag cagcaatcgt tgaagatgct
      901 aaatctcata tcgactggtt cggttcagct aacaaagcgt aagcatccac ataacagata
      961 cgatatatag gaatggagaa cgacttttga agtcgctctc cattcttttt tacttaaaac
     1021 ggcagaccat gctcgtttct tttttttatc tatgataaaa tacaagcata tccatgaaaa
     1081 aagattaata aacaaggtgg aaacagatga aaaaaatcgt aatcaaagga aaccgacctt
     1141 tagctggtga agtaacgatc agcggtgcaa aaaatagtgc agtcgcattg attccagctg
     1201 caatcttagc tgattcccca gtgatcttgg aaggtgtgcc ggacatacaa gatgttcatt
     1261 cattaattga aattttagag atcatgggcg caactgtcca tttttccaac aacatactag
     1321 aaatcgatcc tcgagaagtc gtatcgattc cgatgccgca cggaaaaatc aatagtttgc
     1381 gtgcttctta ttattttatg ggaacactgc ttggtaaatt tggcgaagcg gtagtaggcc
     1441 tgccaggtgg ctgttattta ggccctagac cgattgacct acacgtcaaa ggatttgaag
     1501 ctctaggtgc tgaagtgaca aatgaacatg gtgccatgta tttacggaca gaaaataaag
     1561 gattgcgtgg caatcggatt ttcatggacg tggtttcagt cggagcaacg atcaatgtga
     1621 tgttagctgc tgtaaaagca aaaggacaga cagtaattga aaacgctgca cgagaaccgg
     1681 aaatcataga tgtggcaact ttactgaata atatgggggc aaaagttcga ggagcgggta
     1741 cagatgtgat ccgtatcgaa ggagtcgaaa cattacatgg ctgtcggcat ttcatgattc
     1801 ctgaccgcat cgaagcagga acctatctag cattagcagc tgcagtagga aatggtatca
     1861 aagtgaaaaa tgtgatcttt gaacatttgg aaagctttat agcaaaattg caggaaattg
     1921 gtgtccatat gaaaatcagc gaagatgaaa tcgaagttta cccctcgaaa gaattaaaac
     1981 ccgcaaacat catgacctat ccttatccag gatttgccac agatctgcag cagccactta
     2041 ctgcgttact attgatgact acaggcactt cagaaatcat cgatacgatc tatgcgaaac
     2101 gtgtgaacca tgtgccggaa ctagcacgaa tgggcgctga tattaccgtg gaaggaaata
     2161 tgatcatcgt gaatggtcca aataaacttc acggcacaga agtcgtggct tctgatcttc
     2221 gggcaggtgc ttgtttagtg attgctggac tattggcaga agggacaacg acgatttaca
     2281 atgtagatta tatcttacgc ggttatgatc atattatcga gaaactaaca gccttagggg
     2341 catcaattga aatgatagag gaagtgggag ctgaatgagc gattatttga caatggcaga
     2401 actagagaac aaaacgttaa aagaagttta tagttatgcc aaagaattta aaattcctta
     2461 ttacagtaag atgaataaaa aggaattatc tctagctgtg attcgtgcac aagcagagaa
     2521 acaaggattt tattatatgg aaggaatatt ggatatcgtt ggtcaagatg gttacggttt
     2581 tttacggcca atcaattatg gaccaagtgc agaagatatc tatatttctg cctcacaaat
     2641 cagacgattc agtttgagaa atggggacaa agtggcagga aaagcccgtc cacctaaaga
     2701 atcggaacgt tattatggtt tgatgcacgt ggaaagcgtt aatggaaaag atccggaaga
     2761 agcaaaagaa cgtccgcatt ttccagcctt aacacctctt tatccgcaaa gacagcttca
     2821 actggaaaca acaccgcaaa gactatctac ccgaatgatc gatatctttt ctccaatcgg
     2881 ttttggtcag cgtggattga tcgtcgcacc gccaaaagca gggaaaactt ctgtattaaa
     2941 agaaatcgca aatggtatca ccgaaaacta tccggaagta gaattaatcg ttctactgat
     3001 tgatgaacga ccggaagaag taacggatct agaacgaagc gtgaaaggcg acgtggtatc
     3061 ttctacattt gatctgcagc cgcaaaacca tactcgagtt tctgaattag tattggaacg
     3121 cgcaatgcgt ttagtcgaag ataaacgaga tgtcgttatc ttgatggata gtattactag
     3181 acttgctcgg gcctataact tagtcgttcc accaagcgga cgtacattga gtggcgggat
     3241 tgacccagcc gcattgtata aacctaagaa atttttcggg gcagcaagaa acatcgaaga
     3301 aggtggcagt ttgacgattt tagcgaccgc tttagtcgat acaggaagcc gtatggatga
     3361 cgtgatctat gaagaattca aaggaactgg aaatctagaa ttacaacttt cacgtgaatt
     3421 atctgaacgt cggatcttcc cagccatcga tatcaaaaaa tcaggtaccc gaaaagaaga
     3481 attattgatg ccaagtgaag aattagaaga aatttggaaa cttcgaaaaa atatgactgg
     3541 agattcatta gaatatacgg aacaactgat ccgctttttg cgtaaaacaa aaaacaatca
     3601 gcaatttttc aaagaatttc aagatgtctc ctttggtaaa aaaaatccga ccagaaatct
     3661 gaaaagataa ttgcaacctt gactgaaaca tgttaagatg ttaatgttgt aaatcgacaa
     3721 atcaactctg gttcagcaaa tggagcaggg caaaggagcg aaaaaatcat gaaagaaaac
     3781 atccatccag attaccaccc agtagtattc atggattcaa caactggttt caaattcttg
     3841 tcaggttcaa caaaaacttc acaagaaaca gttgaatggg aagacggtaa tacataccca
     3901 gtcatccgtg tcgaagtaac ttctgactca catccattct acactggacg tcaaaaattc
     3961 acacaagcag acggacgtgt ggaccgtttc aacaaaaaat acggtctcaa agacgcaaac
     4021 gctgcggaat aataaaaacg ctgataactc aacgtttagc agactatctg atagggatag
     4081 tctgtttttt tatgtttttt gccaatttaa aacttcgttt gatgctgaaa aagtcgtagg
     4141 atcataatgc acaaaacaat gaaaaactag tatatagttt taattatcca cttgataaaa
     4201 acaccttata ttaacgaaat gaagaggggt tatttcgaag taaaaaacca tttacctaaa
     4261 attagaagct aagctttcct ttcaaggaag gctttttgtt ttgttataga cttgcgattg
     4321 tttgtgagct agatcgttca ttttaatgac ttatacacgc ggatgatggg tctttttcct
     4381 ctgttcattc ataatattga acggtacagc tagcgatgct atactgacct cagttccaag
     4441 aaaacgttaa cattttttgt gggggagagg ttttttatga ggtttgatca attgatcgca
     4501 gaagaactga ttgttttcga tccatcgata gattcaaaag gatcattatt tgagcgaata
     4561 ggggatgtgt tgaaaaaaac aaataaggta agaaatgttc aaaaagtcgt taaggcacta
     4621 ttcaaacgag aggaggagat ctccacagga atagaagatg gatttgggat tccccatgca
     4681 aaaagcaaat atgtgacaaa accagcactg tgtttttttc atacagccaa attaacggac
     4741 tatagcggga tagatgaaat gccaattgaa tatatttttg ccatcgtagt tcctgaaaaa
     4801 tcagcagata tgcatctaga gattctcagc acactctcca gacgattgat gaatgcagat
     4861 tttagaaagg gaataaaaga agccactacg ccagcagata tcatcagaca gattagtcaa
     4921 gaatgaaaat agtagagtct ttgtccgagt atcgatagtg aagaaaaagg aggaaaataa
     4981 tcatgaaaat cgttggtgta actgcttgcc cgactggaat tgctcatact tatatgtcgg
     5041 cagaaaaatt agaagtaaca gcaagaaatc taaaccatca agcaaaattc gaaacacaag
     5101 gtgtaaaaac agaaaatcag ttatctgaac aagaaatcaa agaggcagat gcaatcattc
     5161 ttgcagtaga taaagaaatc gaattggacc gatttgccgg gaaaaaagta aagcgtgtct
     5221 ctacaagccg agcaatcaaa gaaccgcaag tagtaataga cgaagcattg agagatattg
     5281 gcgtattcgt tgtgtctaat gaaaaagaac cagctgcaaa tgagaaaaag ccgacaatct
     5341 ataatcattt catgaatggt gtgaattaca tgcttccatt tgtgatcgca ggcggaatca
     5401 tcatcgcact gagttttgcc tttgggatta cagcggctga tcccaactca gcagactata
     5461 atgtgttagc agctgcattt tcaaggatcg gaggagatac agcgtttgcc atgatggttc
     5521 ctgcgttagg cgcggggatt gctacatcga ttgctggaaa agcaggtttt gccccaggaa
     5581 ttgttgccgg attactggcc tctacaggtg gttcaggttt tcttggcgga atgattggtg
     5641 gcgtgctagc agggtatatc tgtgattttc tggcaaataa aattagcgta aaaaaagaat
     5701 tttctgctat ttatcagctg attgtcgtcc cctttttatc gatcttaatt attgggcttt
     5761 tgatggtatt tgtgattgaa caaccgatca catgggtgtt ggatgctttg acaaattggc
     5821 tgaatagctt gggaaataca tccgggctat tgttcggatt acttatcggg atcatgatgg
     5881 cagctgatat gggtgggccg atcaataaat cgacttcgac tttctcgatc ggtttgatgt
     5941 cagctggagt aaatgcaccg attgctgctt gtatggctgc aggaatgaca cctcccctag
     6001 gtattgcttt agccacttta ttattcaaac ataaatttac caaagaagaa cggacttcag
     6061 gtcaatcatg ctggatttta ggcgcttcgt atattacaga aggtgctata ccgtttgcgg
     6121 tatctgaccc gatccgcgtg atacctagtt tgatgacagg ttcagcagtc gctgcaggga
     6181 tttccatggc agtaggagtt acttcaatgg cacctcatgg agggatttgg gtgatgctaa
     6241 ttccaaatgt tatgaacaat ttacctatgt atgtcttggc aattgcatca ggtacagtca
     6301 ctacagcctt tatgcttgga ctattgaaaa aaacagtgaa agagaaaaaa caagacaagt
     6361 ggacgaaaaa tgaaaatcta acaaatgagg tggaagcgta atgttatata caatgaaaga
     6421 gttattgaaa gtggctaaag agaatcaatt tgcagtacca gccttcaata tttgcagcta
     6481 tgatatgatg aaagcaatca tcgaagaagc agagagatta gaagcaccag taatcttaga
     6541 aattcatcct gatgaaatcg cctatttaag tgatgagttt gttgcggcag taagagccta
     6601 tgcttataca agtaaactgc cgatcgttat ccacttggat catggcggta cgatagaaga
     6661 tgtcttacgg gcgattcgaa acggctattc ttccgtgatg atcgatgcgt ctttgaaatc
     6721 attcgacgac aatgtacaga ttacgaaaaa agtggttgcg ttagctcatg cggtaaatgt
     6781 ctcagtggag gctgagcttg gaacgattgg gaataatggt tctgctgaag gaggtgctga
     6841 aacaatcatt tatacagatc ctgatcaagc gaagattttt gtgaaagaaa caggaatcga
     6901 tacacttgct gtagcaattg gaacagcgca tggcttgtat ccgaaaaaca gaactccaaa
     6961 attaaatatc gacttactga aagaattgaa ccaacaaatc gatcttccat ttgttttaca
     7021 tggcggttca ggtaatccgg acgcagaagt cagcgaagca gtaaaatacg gagttgccaa
     7081 agtgaatttg agctcagatc ttaaaagcgt ctttttcaat gctttgagag aaatattgag
     7141 tgaaaatcca tcgatgtacg agccgaatgc aatttatcca gcagctaata aaaaggtaca
     7201 agaagtggtc aaacataaaa tggaaatttt gaacacagta ggcaaggcta gtttatacta
     7261 aaaataaaaa tgtgtggtca agagggtatg acaatagtct tgtcataccc tcttaaccac
     7321 acacgatgtt cagaagtagt tttttcgaaa aatttcttct tatttctcga agccaatcac
     7381 ttctgtcaca acctcttttt tcctgttact atataaagta aatggggtga ttttatgttg
     7441 aatgaagtgg agaatagaca gcaggagatt gtgaattatc taaaaaacaa ccaatttgca
     7501 agagtcaccg atttgatcga gttagtaaat tatagcgaag ccacgattaa acgtgacctt
     7561 gtttttctgg aaaaaagtgg attgatccgt agagttcgcg gtggcgccat gcttattgac
     7621 aatcgaaaaa ttgacgtgcc ttacctgatg aagatcacca aattagaaga agaaacagaa
     7681 aaacgtaaga ttgcagatac agcttcttct ttgattcgag atgatatggt cttattcttg
     7741 gattccagta caacctcttt acacttagtc agaaacctag caagatttga tggtttgcag
     7801 atcattacga atggcatcgt cacagctgct atgttgagtg aatatacaac ggcaaaagta
     7861 tctgtattgg gaggggcaat tgttccgaaa cgagcaacaa tcaacggttc aaaagcctat
     7921 aacgatgcat tgtcatatta tgcggattta gcgataatga gttgtcgcgg gctagatttc
     7981 agccaaggag taacagaaac tcatgaagga gaggcaatgg tcaaaaaagc ttttagaaaa
     8041 caatcagacc ggcttgccgt tttagttaca cagcaaaaaa ttgcacataa attcatgcat
     8101 caagccattg cttttcatga aatcgattat ctggtgacaa gtaaagaact gacaaaagaa
     8161 cagtatgcga aagtaaagga acaccatatc gaatgtctgt acggataaat tattacgtga
     8221 atgttctaag tggcttcctc atttttagat aggaccttat ctttgctcgc ttctctcagc
     8281 cgatggtata ataatgaaaa ggttatcttg ttagataatc ttactttttt atccaggaga
     8341 aaggagtgca gaaaatgaaa catgtgaagg cgttggtagt gaaggcaatc atgatctggg
     8401 cgattctgtg ggtcgtgctg acaggtttat acggtgttag ctttatggat tcaacgattg
     8461 ttggggtaat tattgtagtc atgatctatg tgctagggga tctgttgatc ttacgtaaag
     8521 tagggaacat cgcagcgacg atcgcagatg ctggttcagc tgcagttatc ttgtggctct
     8581 atctatattt tatgaatgat acagtcgata tttggatgaa agtattgatt cctgctctat
     8641 tgatcggtgt ggcagaatgg ttcttccaca agtggttgct aagtcaaggc atcgtaccag
     8701 atgaacggaa aatggaataa atcaacagtt aaactattct tatcgataaa tgaaagcttt
     8761 aaaaataaat agatgtttaa ttaagaataa tcataaacta tttttactca aaaaaccgct
     8821 cagattattt tcagatctga acggtttttt ttatctattc atcaagatca aatttcattt
     8881 ttcaatgatt caatcaattc gccctctgct tcatgactat gttttcggcc attaacaaga
     8941 tagagtgctg tacatatcaa tggaatgact ccggcaatca catacaatcc tctaaatgaa
     9001 gtaagagatt ttagcatccc catcaaataa ggaccaacgc ctaagcctag gtctaaacca
     9061 ataaagtagg tagataaagc aatactgatt cgatgttcgc ggacgatttt taaacaaaca
     9121 gcctgtccat ttgacataaa cgtaccataa cctaggccga ctaatgctcc agagataagc
     9181 aatgtcacac tattcgtcgt tacactcagt aaaaataatc ctgctgttaa gaataaatag
     9241 ctaggataca tcacgtattg ttctcctttg acatcgaaaa tccttccagt caatggacgt
     9301 gtaaatgtga tgaccaaagc atatacgacg aagaaaaatg acccagcagc aactaagtgg
     9361 attacttttg tataagaaga taaaaatgat aaaacacttg aataagaaag acccatcaaa
     9421 aaggcaattc ctgtaatgaa aagtgctttc ttttcaataa aactattgat attccatgag
     9481 cgaagagata ttttttgttc ttcagataat ggaatatttt ttacaggaaa gacaaggcag
     9541 gcaatcgtaa caaagaagac cagtacaatt gaaaaccaga taatgaaacg aaaatcagtc
     9601 atattcagca aaatcattcc taaaaatggc ccaacagcgg cagctaaact agtacttaat
     9661 ccataataat tgatgccttc ccctttttta gatgcaggga tatatgcagt aacgatagca
     9721 tttgtagctg tagaaactgt accgtagccg aatccattca agaatcgaac taaatacaat
     9781 gccccgatag ttggcgtata aagatatgct aatgttgaaa ggagatagaa gatcgcgccg
     9841 cctcttaagg taaacttccg accaaatagt tctaactgtt tccccatgaa taagcgtgcc
     9901 agcaatgttc cgatgatata gatcccagaa gcaaaacctg cttggctcaa gctggcgtgt
     9961 aaggtgtctt gcgcaatgac tgccatgatg accatcaaca gataataaat caggtagaca
    10021 ataaaattga tcaatgtgat tccaataaaa tatttattaa ataatttctt ttccatgtat
    10081 gttatacatt ccccttaagc tgaatatgct tttaattttt gtatttgaac ttctacatcg
    10141 tgataattgg atggatagcg atcaacaagt tggcgaataa ataaatctct tgtagacata
    10201 aacagattta aaaattcttc gcattcgttt gttggattct catccactgc tttgatcaat
    10261 tcgatcgagt tttgatacgc atcatttaaa aagactaaag aagctttcat atcaaatctt
    10321 gtttgatatg ctgtttctaa tcgattaatg attgtgttca tccagtaatt catgtttttt
    10381 ccctctattc ttaaaaaatt ttacttctgc agtataacga ataaaaaaaa ggaaaaaaat
    10441 cgcataagtg atggaaaaag gtacttaaca aatgttaata tcattagtaa aatacctttg
    10501 gactttaaaa agttttaaag tactgtatga tctttttaga tgaaagtttg gatgggggag
    10561 catcattgga tagtagagtc ttaaaggaat atttggataa aaatgatttt ccgattatac
    10621 gcaaaggata tcataaatat ttgacattcg aagggatgga agattcccat acgtatatct
    10681 tgaaagaggg aacggtaaaa gcaagtgtta tttcaaatga tgggagagaa tttaaccttc
    10741 gctatatcaa agatcttgaa atcgtctctc ttttaaaaga cgaatattca caattcatcg
    10801 attcgccgta taatattcga gttgaatcag aatatgcaga gttttatcga atcaatcgtg
    10861 tgcgcttttg gcaaaatatc aaccaagacc caaagctaca acactatgta aaagagtatt
    10921 accgctatcg tctgctttat tcgatgaaaa aaatgcagca aatgctatta aacggaaagc
    10981 tgggagctgt ttgtacgcaa ctttacgaat tatatgattt attcggtgtg cggacagaag
    11041 aagggatgct gatcgatttt tcgatcacga atgaagaaat cgccaaattt tgtggcatct
    11101 caactgctag cagtgtaaac agaattttaa aacaactgaa aaaagatggt attatcaccg
    11161 ttaaagacca tcatatcgtt attttgaata tggacttgtt agaagacaat attatctttt
    11221 gatgaacaaa gaggttgtga aatcagcgtt ttgacctgag tattagagaa acaaacggaa
    11281 aaatagttcc tcatattttg ccgttttttg agctaatacc gagggtcagc tgattgaaca
    11341 ccgtttacca agaggttgtg agcctgccgt ttaactctga gtcacaagga acaatttcaa
    11401 aaaacagctt ttcatgtttg atgaatattg tgacttgtga ccgaggagtt ggtaggagaa
    11461 caccgtttac caagaggttg tgaaaaagct gttctgcatc aagtaataag aagagccaag
    11521 taaaaacagt ctcttatgtt tttaacttgg ctggacttat caccgtagat gtaagctttt
    11581 gaacgccgtt tatttgcaac aaaaggggct gtgacacgat ttttgtcaca gccctttttt
    11641 tgcgaacatt catttagcaa tttttagaaa cttctgccgc caccgccaaa agtcccgcca
    11701 ccgctagaat gggtagtact tccgccaccg ccgcttccag gaggtgggct tttggggatt
    11761 cttcttgtcg tgacaaaaga atttgtcaga cgatcggttt tttcagttaa tttgatactg
    11821 gatttttctc ggaatggata tttgtagatg cctgatttca attgataacg cgaaacagtc
    11881 acaaaataaa agacaagact aaggataaga gccaaaacaa cagcaatgat gatttctact
    11941 gtcgtcaaaa ccttatagcg tgtaattttg ccagtttctt cgtctacacg ataatgtcct
    12001 cctggaactc cgtcttccac atatgttgct gatttagaca ggtaagcttt tgcagcattg
    12061 taataggcag catttgtcat ctgatcataa acatcatcta agatcgaatc gattctgcta
    12121 tcagtcaaat aatcgatcat attaccagaa gtcgaaatgt agatttcacg ctgtcccata
    12181 tctaatagca atactgagcc attttgatca tttccgactg cgtctcttaa gtaattatca
    12241 gcaaagtctc ttggttcttc tgaattagat gtagtcgtta cgatcaagac tcgtcctttg
    12301 attttttcat tcagcttttc tgcctgttgt tccaaagatt ggatttgatc tgttgtgaat
    12361 aacccagcct catcatttac cgtagctgta tctgcatgag tagccaccgg ccagccaaca
    12421 cttactagca aaagaaagaa taaaaaaaat tttttcatca tatcaagtaa cctccgatca
    12481 gaaagaggat cgctagccca gcgaaaatcc caagagcggt cagtcccaat tttttctggc
    12541 tgatcggcag gacaccgctg acctttcctg tttgtccatt cattgcgtag tagtagactt
    12601 ttttacttga gtcattgctt cgataagtaa caagccatac cggcagtaat acgtaattat
    12661 ttacttcgtt tgtgattgaa gcagaagttc gcacaccggt caatgttgta tatccatttg
    12721 cggtatcttt taacagcttc tctgaatagt cttttaattc agattgaatc tgtgatttga
    12781 ttgcctcata ttcgatatct cttttttctg cttggaaccc ggctaaatac tggcttttaa
    12841 aatcaattgc tttatctaac gggaaaggtt gcacgccttc gaccatcttt tgttgcgtat
    12901 tttttgataa ggcatttttt actagttctt taaaagaaag cttgcctgct cttgaaacag
    12961 caaattgctt cgtttctgtg tattcgatgt cacctatccg ccatatgcgg ataactgtac
    13021 cattcgcctg catggcacca tctacttcag catctgtagc ccaataaggg aaatacacac
    13081 ctgtcaactt atcgatttga tccttattga aaaaagcttt gggaacaaac cattttttct
    13141 tggtccaagc gagaaatctg ttgattgctt cttctttctc gacagcaaaa ggaagtactt
    13201 tatttggcaa gaattctccg cttaaacgtc ccgatagtac gacgggatta tggcagtagt
    13261 aacaataagt cgcagcagtt gtcgcatcag tcacgatctc tgcaccacag ttgggacaaa
    13321 gaaaaagatc tatcgctgcg gtattatctg cagattcgtc cgctgtatct gaaaaaccgc
    13381 ctgcctcgtc aaccgctttg cgctcggctt cattcatatc ggcaagctgt tcttgggctg
    13441 taaaagtaaa atcttcggta ggtgaaggtt cttctttgct ttcttcgcca gccatacgcg
    13501 cttctttttg cttttgctca tattggctga cttcttcttc tgtatagata ttcaggcagt
    13561 attcgcaatg aaatttttgg tctttgggat caaaagtcaa cggaccgccg caattaggac
    13621 atttatgtgt aagaacatcc atcagctgca cacctttcta aataaattaa ttaacgggga
    13681 ttcctttaaa cggtttacca cagtttggac agaatttagg gatgccgttg gaaagatcca
    13741 cgatctcatt gcattcactg catcgcattt gtagcttagg ctgaacgttt tctacaggtt
    13801 tggcagctcc gcagttggaa cagaattttc cggaattttc tgtcccgcaa actggacatg
    13861 tccaagtatc cgcatttcct tgtgcagttt gttgattttg tttttctgct tgttgtttga
    13921 tttgttcttg gttattttga gctgcttgag aaagataaga accatttgca ttcattccca
    13981 tacctacacc cataaagccg gtcattgctc ctgcttcatt ttttccggct gcttccatac
    14041 cacgtgcaat ggaaccttgc acgtagcctt cacgtacgct aggatcacct agcatcgccc
    14101 cttcgttacg catattgatc agtttcacag aatcatcggt gtaagaaatg ctggctacag
    14161 ccacagaaac aatctccatc ccacgtaatt cacgccaaga atcatccaat gcagtatcca
    14221 tgtatttgct taattccaaa ctcttagatg gtacataaga aatccgttga ccatctgcag
    14281 acatctgatt gattgctgat tgtagcgctg ttaggaattc agctaaatac tgctcattga
    14341 tatcattgat ttccacttgt gttttgtttt tagggattgc gtttgtataa aataaaatcg
    14401 ggtcaacgac atgaatagaa taagtgccat gtgcccgtaa gaataattct gcgttataga
    14461 aattgtcaaa gtagttcaac ggcgcgcttg taccgaattt gattcccttt atttcttgga
    14521 gattgatata aaaaacttgt tgtttctgcg gtgtgacgcc gccaaatttg aatcggtcaa
    14581 aagtttcagc aattgcttct ttcagtgttc cattgaacat ggaaggagct gcgtcatttt
    14641 taatggtgta ataaccttcc tcagcggtat aatcgatgat ttttccacca tcgaccaaaa
    14701 gcatcatcat gtttggatag acatggacga ctgttccgtc tgttaaaaca tcttctgttc
    14761 ctttacgatt ggagccacgt ttgtcatctt tgcggacttt gacacctttt gtcatgaccg
    14821 ttgtatcact catattgtct ggttcgatga cttctagcca ttgatctgcc agaccgccgc
    14881 caaccatact tgttgctgct ttgataagac ccataaaaaa ttcctcctct gattcagcta
    14941 gtgccaaaca attattgttt atttattata ccataggaag atgtgaaact tctcggacta
    15001 gagacggaat tgaaatggaa aattgcgtat tgtttaaata cctgaaaaag ccgagaagga
    15061 tagtagtttt tttacctaat atcacgtata ataagagata gtgaattttt taaaaaaggg
    15121 ggatccttat ggcatatcaa gcactttatc gagtctggcg ttcgcagcgt ttcgaagaca
    15181 tcgttggaca aaaagctgtg acacagacac taaaaaatgc tattgtttcc cacaaaacct
    15241 cacatgccta cttgtttaca ggacccagag gaaccggaaa gacgagtgca gcaaagattt
    15301 tcgcaaaagc aatcaactgt ccgaacagta aagacggtga gccatgcaac gaatgcgaaa
    15361 tgtgtcgatc aattactgct ggtacgcaag aagatgtgat cgaaatcgat gctgccagca
    15421 ataacggagt cgaagaaatc cgatttatcc gtgatcgggc aaattatgcg cctacaaagg
    15481 cagcgtacaa agtgtacatt attgatgagg tacatatgct ttcaacagga gctttcaatg
    15541 ccttgttgaa aacattggaa gagccaaaag aaagtgtcat attcatctta gcaacgaccg
    15601 aacctcacaa aataccagct acgatcattt cacggactca gcgatttgat tttaaacgga
    15661 tcaatacggc agatattgtc gaacatcttg aatttatctt gaaagaatcg actatcagct
    15721 atgaaccagc tgcattgaat gtgattgccc gttctgcaga aggcgggatg cgggatgcat
    15781 tgagtattct tgatcaggca atctcgttta gtgaaggaac aattacttta gatgatgcca
    15841 tgcaagtgac aggtagctta actgacgaaa tgatggacag ttacttgagt gcttgcgtga
    15901 aaaaagaagt accagaagca ttggaaacat tgaaccaaat tctcgcagcc ggcaaagaat
    15961 cacgtcgctt tctagaggat atgttacaat actgccgtga cttgctgatg tatcagcaag
    16021 cacctaacct agttgaggaa caatcgagta cgatcagaag tacatttaca gaattggcac
    16081 aaactgtttc agcggatcag ctgttttcaa tgataaagat tttgagcgat actcaaaatg
    16141 aaattcgttt taccaatagt gccgctattt atttggaagt cgctacagtc aaacttgcac
    16201 agctaccgtc tgcttctgtt ccttcagcag atgtagcatt tgcagatgat cagatagtaa
    16261 aacagctaca acaagagatt aaggaactaa gaaacgaaat caaggaacta cgcagtaata
    16321 caggaattga gaatacaaaa gtacagccgg tacagcaaac aaatcataaa aaacagacaa
    16381 gtacctatcg tgtaccgacg gaacgagtat ataaagttct gcgggaagcg acaagacagc
    16441 atctgaacca agtaaaagaa gtatgggaag acttgctgat gagtctatct gtcactcagc
    16501 gagcaatgct taaagcaagc gaaccagttg cagctggacc tacaggacta gtgattgcgt
    16561 ttgattatga gattgtttgt caaagagcag caaatgacga agaattgcag ctttcggtac
    16621 acaacaactt aagccgaatg atcaaagatt atgcgcctga tcctgtttat attacaagag
    16681 aaagctggcc agaacttcga agaaattatt tgacgcaggc acaagaagag ggaacagaaa
    16741 actcttttgc ttctgaagac tcagaaggag aaatcgagtt gcttcctcaa gaacaagaag
    16801 taccagaaga aacacttgta gtaaaagcag aggaactgtt tggctccgaa gctgttacag
    16861 tggtagatga ttaataaaaa ggagtagata attatgatgc gtggaatggg caatatgcaa
    16921 ggcatgatga aacaagtaca aaaaatgcaa aaagaaatgg cagaagcaca agagctgcta
    16981 aataaaacag agtttacagg taaagccacc aatgaattgg tcaaagcggt ttttacaggc
    17041 gatcgtcgca tgaaagatat ccaaatcaat gaagaagtcg ttgatcctga tgatatcgag
    17101 atgcttcagg atcttgtcgt aatggcagtc aatgatgcga tcgcacaaat tgatgtggaa
    17161 actgagaaaa aattagggaa atacgcaaaa ggtttgccag gattttagtt ttaaactgaa
    17221 ggagtaatga atatgcaata tccagaacca attgcgaaac tgatcgacag ctacatgaaa
    17281 cttccaggaa tcggtcagaa aacagcgaca agactcgcct tttatacgat cgatatgaaa
    17341 gatgaagtag taaatgaatt tgctaaatct ttgttaagtg taaaacgcga tttgcatttt
    17401 tgtagtatct gcggaaacat cacagaagaa gatccctgcg aaatatgtag aaatccttca
    17461 cgtgatcgaa gcgttatcct agtggtcgaa gagccgaaag atgtaatggc aatggaaaaa
    17521 atgcgagaat atcacggact ttatcatgtt ctccatggtg tgttatcacc gatggaaggg
    17581 acaggtccag aagacatcaa tatttcttct ctgttgcagc ggctgcatga tgcagatgta
    17641 aaagaagtga ttatcgcaac aaatgcaaca acagagggag aagcaacagc tatgtatctc
    17701 tcacgtctga tcaaacccgc aggtatcaaa gtgactcgtc tagcacatgg tctgtctgta
    17761 ggctctgata tcgagtatgc agatgaagtt actttattga aagctgtcga aggaagacgt
    17821 gagttataaa tttctaatta agtgtttttt cagatacaat ataaaagcag cacaagagat
    17881 gggggcaaca atgtgaacgg actatttatt acaatcgagg ggcctgatgg tgcaggaaaa
    17941 accagcatct tgaatgaact ttaccctctt ttgaaagaag tagcaaaaac agaaatcatt
    18001 caaacaagag aaccaggagg cattccgatt gctgaagaga tccgagcagt gatccttgat
    18061 ccaaaaaatg atcggatgga tgaacgtacg gaagcactgc tttatgcagc agcaagaaga
    18121 caacatctag tcgaaaaggt tctgcctgct ctggcaaaag ggaaaatcgt tttatgcgat
    18181 agatttgtcg acagttctct tgcttatcaa ggtgcaggcc gacgcatcgg cgttaccgag
    18241 attgctcggt tgaatgagtt tgctacagaa ggtactacgc cggattttac cctttatctt
    18301 gacgtagatt cagacaccgg attaagaaga atcaagaaaa acagacaaaa tcaaatcgac
    18361 cgtttagatt cggaaggttt ggaattccac cagcgtgtac gtcatgctta cttaaagctg
    18421 gcagaagaga atccggaaag aatccacaaa gttgatgcaa gaaaaagctt tgaagaagtg
    18481 ctgcaaacaa gttatcatac aattattgaa cagtatccgc aattttttga aaactaggaa
    18541 ggtgaacgtt tatgaaaatt attttagcga ttatccaaga caaagacagc aaccgtttat
    18601 caaatgaatt gattgatgca aatatccgtg ccacaaaact atcatcgaca ggcggcttcc
    18661 ttaaggctgg aaacagtacg tttatcgtgg gtattgaaga tgaccgtgta gaagaagcat
    18721 tggaaatcat caaaaaaacg tgtgaatcaa gaaagcaatt tgtatctaca cctgttacac
    18781 tggatatttc gatggatggg ggcgtccctt atccagtaga agtagaagta ggcggtgcca
    18841 cagtcttcgt cttacctgtt gaaggattcc atcaatttta ggaggagctg agctatgaat
    18901 caagaaataa acttggctca aatgcaaccg atcgtgtatc agcagcttca acggagtttt
    18961 gagcatgggc gtatcgctca tgcttatctt tttgaagggg agaaaggaac aggaaaacat
    19021 gaagtaggta tatggcttgc acagcacctg ttctgtaccc aaatgaaaga caatctgcct
    19081 tgtggaaaat gcaacaattg tcagcggatc gaaaagaaag aacatccaga tgttttggtt
    19141 attgaaccgg aaggacaaac catcaaagtc gatcagatca gacgtttgca gacggaattc
    19201 agtcgcagcg gttacgaatc aagaaaaaaa gtttttttga tcaaagaagc tgaaaaaatg
    19261 aatagcagtg cggcaaacag tttgttgaaa ttcttggaag agccccctgg agatttttta
    19321 gcggtgttag aaacagatgc agtaggaaga attctcccta ctattcaatc tcgttgtcaa
    19381 gttctgcatt ttcaagaact ttcgaaagaa gcactgatcc atcgattgca agaagagcag
    19441 attccattgg aaaaagcaaa acttttggct ttcttaacaa acagtttagg aaaagcagtt
    19501 gaaatctctc aagatgaatg gtttaatgat gctaaggact tgatttatca atggttcgtt
    19561 tacttgcaaa agcaagatac tcaagccttt atctatgtcc aaaaaaaatt ggtaaaatca
    19621 tttaaagaaa aaacacaaca gtttacagga ttatctgtct tgatgtttta ttatcaggaa
    19681 gcacagcgtc aagcagtagc aaacggcgaa tatggcaaag tgaaacagat aaaccagata
    19741 attgaacgga tattgatcgc agagcagaaa ctacgcagca atgtcagttt tcaggctgtt
    19801 gcggaacagt tcgttttgca tacgattttt tagcttgccg caaaggatga tgatcaagga
    19861 ggatggaaat ggtagaagta gtaggtgtcc gatatagaga tgcaggtcat atctattatt
    19921 ttgcaccagg agactctgaa tatgtttata gtgacaaggt attagtcgaa tctcagcaat
    19981 ccttacatat tgctactgtt gtccttccta aaaaagagat tgatcccaat gaccttcctg
    20041 aagctatccg tccgatcttg cataaagcgt cacaagctga attagaaaaa gacaaaaaaa
    20101 acaaaaaaga tgcttatgat gcattgaaaa tcgcaaaaga aaaagtgcag ttgcgtgagt
    20161 tggaaatgaa aatggtcaaa gccgaataca catttgatcg aaataaattg attttttctt
    20221 tcacagcgga cgggcgaatt gactttagag aattggtaaa agatctggcc gctgtatttc
    20281 gtactcgtat tgagcttcga caaattggtg tccgcgatga agcaaagata ataggcggaa
    20341 ttggtccatg tgggcgtcca ttatgctgtt cttctttttt aggcgatttc gtgcctgtat
    20401 caatcaaaat ggcaaaagat caaagtttat ctttgaatcc aacaaaaatt tccggtttat
    20461 gcggacgctt gatgtgctgt ctgcaatatg agagcgaaga atacgagaca gcgaaaaaag
    20521 aactccctga ctttggaaaa gtaattgcta cacctgatgg taaagggaaa gtcgtagggt
    20581 tgaatctgct tagccgtatc gttagtattc ggctgactgg acgggaaaat cctgtcgaat
    20641 atgaatggga tgaattgaaa gaatttatcc aagtaggtga gatgaatgga taagagatca
    20701 ttatacgacg gattgaatca attagaatca gagttgagaa atacattaac agaacttgtt
    20761 gaaatgaagc atgctttgca tgagatcgta gaaaaaaata caactttgga gatggaaaat
    20821 caacgtctgc gggaacacct gcgggaattg aaccaagttg cacaagctcc agctgaaaat
    20881 gtgaagcagg aactttctaa gtctcgtatg aatcttgaaa aaatttatga agaaggattc
    20941 catgtctgct acgatttata tggatcaaga agggacaatg acgagccttg tgcgttttgt
    21001 ctagaagtga tctatcgcga aagcggtcga tgaccaataa caagaggaga ctggagcgga
    21061 gaaatactgc tccagtcttt ttattaagga gattgtgaca gatgtataat caaaaaagtt
    21121 tcaagggaaa tccggtatat ggggatttat atcttgtacc gacgccaatt ggaaatttag
    21181 aagatatgag ctacagaagt gttcgtatgc tgcaagaatc cgatcttatc gcaagtgagg
    21241 atacgcgtaa tacacaaaag ttattgaatc attttgaaat ccatacaccc caaaaaagtt
    21301 tacatgaaca taattataaa gaacgtgtcc ctcaattgat tgctttgtta aaagaaggaa
    21361 aaacgattgc tcaagtcagt gacgcaggaa tgccttccat cagcgatcct ggacatgagc
    21421 tagttttagc ctgcataaaa gaagggattt ctgtgatctc tatcccagga cctacagctg
    21481 ggatgacggc tttgattgct tcagggctag tgcctcaacc atttttattt tatggcttcc
    21541 ttccacgtaa gaaaaaagaa cagaaagaaa cattgaaaaa gctaaaagaa cagacagtta
    21601 cgctgatttt ttatgagtca ccttatcgga tcactgctac attgacgaat ttcttagaaa
    21661 tttttggaaa tcgccaagtc gttttgtgtc gggaattgac aaaggtccat gaagaatacc
    21721 ttagaggaag tacggaagag ctactcgctt atatcgaaga acatccagta aagggtgaat
    21781 gttgtctgct tgtagaaggg aatttgttcg aaatgccagt gacggaagtt gatgaagagt
    21841 tgggaacgtt aaaggaacaa gtagaagcaa agatcgcttc aggcgaaaaa ccaaatgctg
    21901 ctatcaaagc agtagcgctg aaaaatgggc tgaaaaaaca agaagtctac cgtcagtacc
    21961 atgaattaga ctgagatagt ataagttgtc tataatgaaa gactaatgag gaaatcagct
    22021 actaactttt caaatctctt gaacgcgaac gaatgttctt gtataatgaa taagaggtga
    22081 ggatgatgga gctgcaattt cctttacata atgatacatc aagaaaaatc attcatattg
    22141 atatggatgc ttttttcgct tcggttgaag aacgagatca tcctgagttt cgcggacatc
    22201 cattagtaat tgccagacac cccagtgaca ctggtgggcg tggagtagtg actacagcaa
    22261 attatgaagc aagaaaattc ggaattcatt cagcaatgag tgcacaaaaa gcgtatgagc
    22321 tttgtccgca agccatcttt aagcctggcg accatcataa atacagcgat atttccaaac
    22381 aagtacggga agtattctat cgttatacag atattgtgga accagttagt atcgatgaag
    22441 cgtatcttga tgtgaccgaa aataaaatca attgcaagtc agccatcaaa atcgcccgaa
    22501 tgatccaagc agatatttgg gagagtgtcc agctaacatg ttctgcggga gtaagttaca
    22561 ataagttttt ggccaaatta gcatcagact atcaaaaacc tagaggaatc acggtagttg
    22621 cccctcaaga cgctgtgcca tttttaaaag ctttgccaat tgaaaaattt catggggtag
    22681 ggaagaaaac tgtacctaga atgcatgagc tagggattta tacaggaaaa gacctatatg
    22741 aatgcacaga aatgatgttg attcgaaatt ttggaaaaat gggctattct ctttatcgta
    22801 aagtcagagg aatccatgat tctccagtaa acgttacaag agagcgaaaa tctgtgggaa
    22861 aagagcatac ttatgggcag ccgttgcaaa cggaagaagc agtgctgact cagttgcgcc
    22921 aactagctga aaaagtagaa gaagcactga gaagagtcca aaaacatggg aaaacagtag
    22981 ttttgaaggt caggtacacg gactattcta ctgtgaccaa aagagtgaca ttgccagaat
    23041 atatctataa aaaagaagca ctcttttatc aagcaagcct tatatgggag gaaatcttgg
    23101 gagtagaaaa aggaatccga ttgttaggga ttactttgac gaatctggac ccgatgactt
    23161 atgaaaacat cgtccttcca ttatgggaaa atcaagaaat ataaaaacag ctttgagagt
    23221 tgaaaccgga aatccgtttt ctctcccaaa gctgttttta tatcaagtct tgctttttga
    23281 tttgttcata ggtttctgtt gcatccgtac atttttccca aatcacaact tgattggatt
    23341 ctaaagattt ttggacgtca atgatccgct ggttgctact tccgcgaaat tgtagtttta
    23401 ggtcacgttt gcttaattca aagcgtccgt caacaaggat atcgatttgc gaaaggagtt
    23461 ctaatttatc ttctgaatct tgtagcaatt catcaaaggt atagcctgtc catgaccaga
    23521 tatcttttgt cgtaccgaac tcttttcgga tacgtcgtac gacttgcaga caaacatctg
    23581 tattcaaaaa aggttcgcca ccaagtaaag ttaatccttg cacgtaatcg ttgcgcaagt
    23641 cagcgatgat ttgttcttct aattcaggtg tgaatggttt gccatatcga aaattttgtg
    23701 cagctttgtt gaagcagcct tcgcaggcaa ataagcagcc actaacgtaa agactgttgc
    23761 ggacaccttc accatcgaca aaattaaacg gtttgtagtc agcaatatag ttttggctgt
    23821 agtcttttgc taaccattct tttggttttg gatttctcat aaaaaaactt ctttcattta
    23881 aggttcaaag atatagctat tgaagataaa atctactcga ccacataaat aagaacaaac
    23941 tgacctaaat ccattgttca agaaagcttg ttcttatttt gatagagggc gttcaaagat
    24001 acaaagccat cgaaagaggg tggtgaaaaa agacttgtca tagcctctta ttctgaataa
    24061 acggtgttca aaagcttgca tctgcagtaa taagcccaac taaacgaaaa atatgaggaa
    24121 ctatttttgt ttagctattc ttattacttg atgcaggaca gctttttcac aacctcattt
    24181 catgtgtttc acacgtgagg aaatttcttt atggcggcca tgtaccatcg gacgagcttg
    24241 cggatttcct aaatagccac aagtacgttt gactacatca catgtttttg gatcatgatt
    24301 tccacattct ggacattcga accctcgttc tgtcggtttg aaatcacctt cgaaaccaca
    24361 ttgatagcaa tgatcgattg gcgtattcgt accaagatac ccgattttgt catatgcaaa
    24421 atcccataca gcttctaaag ctttcggatt ttgttggagc atagggtatt cacagtagtg
    24481 gatgaatcca cctgaacaat attttggata atccttctca aattccaatt tttcaaatgg
    24541 cgttgggttt ttacgcacat catagtggaa actgtttgta taatattctt tatctgtgat
    24601 attttcgatg atgccgaatt tttctgtatc caaacggcag aaacggtcag ttagactttc
    24661 acttggagtt gaatagacac tgaaatgata accatattca tccccccatg catctgcatt
    24721 agcttttaat tctttgacga tatcaagtgt gaaagctttt gcttctgggt ttgtttccca
    24781 ttcgccaccg aagaaagctg aagcaacttc atacaatcca atgtagccta acgatacagt
    24841 agctcgacgg tttttgaata attcattgac agaatcggta cgtgaaagac gtttcccgaa
    24901 agcaccatac atatataaaa ttggcgcatt tgctggaatg gcttctttac aacgttctac
    24961 acgatagaga agcgcatctt tcatgatttc taagcggtca gacagtaact gccagaattt
    25021 attctgatct ccttttgatt cgatcgcgat tcttggcaaa ttcaatgtaa caacacctaa
    25081 attcattcgt ccgacattta cttcttgacc attttcgtct ttccaccctt gcaagaatga
    25141 acgacagccc ataggtactt tgaaacttcc agttaattca acgattttat cgtaattcag
    25201 aatatcagga tacattcttt tcgttgcaca ttccaatgct agttgtttga tgtcgtaatt
    25261 aggatcttca gggtttaagt tcacaccttt tttcaaagtg aagatcagtt tagggaagat
    25321 agctgtccgc ttttcactcc ctaatccatt gattcgaatc tgtaaaattg ctttttgaat
    25381 ttctctttca aaccagtttt ctcctagtcc aaatcctaat gaagtgaaag gagtttgtcc
    25441 atttgaagta aataaggtat tgatttcata ttccaaactt tgcatagcat cgaagatatc
    25501 ttttttggtt tttgcttttg catattcttt ttggcgttct ggcgaatcga tccattcttc
    25561 cgcgtctttt agatgttttt tatagttcaa ttctgcaaaa ggagcaagca attcatctgt
    25621 tcggtcggca gaacagccac catattgact tgacgctaca ttggcaataa tctgtgagat
    25681 ttgtgctgtg gcggtctgga tagattttgg cgattcgact tcggcattgc cgattttgaa
    25741 cccattgttc agcatgcctt tgaaatcaat caagcagcaa ttcgtcatcg gtgtataagg
    25801 atgataatcc aaatcatggt aatggatatc gcctttttga tgcgcatttg ctatatgtgg
    25861 tggcaacatt ttcagtccga ttgattttcc aacgatcccg gctgtcagat ctcgctgtgt
    25921 attgaaaaca ttactgtctt tatttgcgtt ttcgttcacg acagtttggt ccttgttgat
    25981 tagcttttca atcgaaaagt tgatatctgt tgctttactg cgagcaaaat ctcgtttggt
    26041 acgataattg atgtactctt ctgctaattc atattcgttt ttttctagta atatatgttc
    26101 cacgatgttt tgaatctcat agattttgac attttcagca aaccggcttt tgatttcttg
    26161 gacaaccaag tctgcaatca tttgaatttt ttcataagta agtggtgata atgagccgtg
    26221 aattttcttt tctgctttga tcagtgcttc attgatcttt tgttcatcga aatcaacatg
    26281 gcggccatcg cgtttgatga ctttcatctg ggatgtctct ggctgctgag taacgacagt
    26341 tttttcttca taatttactt tcattatctt caactcctgc taaattgttc ttgtctatca
    26401 taaaacaaaa tcggggaagg agcaactaaa tatcggctat atatagtatt caatgtgctg
    26461 tataattgga tttctatact atatgtagtg tatattttat tgtgaaaaaa ggtgaaaact
    26521 tgtagctggt ggatttgttt tttgcatatt taattttgct gaataaaata attgaataaa
    26581 attttttatt cagtccaagt aaaagtgaca aaaacataag agcaaattat tcgtagatat
    26641 gctactatgc aaataaatag aaatgaaaaa tgaaagagga ggagaagaat tggaaaagat
    26701 gatcgaagtg aaacatctaa gtaaaagcta cggcagcaaa ctttctcccg tcaaagcctt
    26761 agataatatc tcattcacag tagaagaagg cgagtttgtt gggattatgg gcccaagtgg
    26821 tgcaggaaag acaacgctga tgaatatctt gtccacgatc aatttgccta cgatgggcag
    26881 tgtctcgatc caaggaaaag aaatcacaaa aatgaaaaac agtgagctca gtgactttcg
    26941 tcgaaaaaaa ctaggattca tttttcaaga gttcaatttg atcgataccc taaatgcaaa
    27001 agacaatatc ctattgcccc tagcagttga acggatgact aaagaggaaa tggaaaagag
    27061 agtaagacat gtagctcaat tgttgaatat agaagaactg ctcaaacggt atcccgatga
    27121 actttctgtc ggacagagac aacgaattgc agctgctaga gcacttgttg ttcagccaca
    27181 agtgattttt gcagatgaac caactggctc tttggactcg aagtcggcta cagaattgtt
    27241 gaactacttg aagaccatga atcaaaaaga aaaagcaacg atactgttag tcacccatga
    27301 tccatataca gcaagctact gcgatagaat tttatttatt aaagatggtg tgattttttc
    27361 tgaagttgtc agaagaggga caagaagaga gttctttgag aaagtaatag acatgcaggc
    27421 gacgattggc ggaggaggaa aaatgaatgc tgtataaact agccgttaaa agtttttttc
    27481 ggcagtcacg aggctatctt gtttattttt tcagtttgac tttatccgta atgatctatt
    27541 attccttcag cgcaatgacc tacgatcaat ctttagtcag aagagcaagt caagatactt
    27601 cgatagatgg tggattgagt tttggtggat ttatcattac tgttgttttg ctttttttcg
    27661 tattcagtgc caaccgattt ttcttgaata gaaggcaaaa ggaaataggc atctatcagc
    27721 tttttggtat gaataaactg cagatatcag gtatatatgt gttagaaatc atgataattg
    27781 gattgttcgc ctgtatttct gggatattac tcggtattat tttttccaaa ctcttttcaa
    27841 tgattttggt tcgaatgatg gatatggatc ttactagtcc attttttatc tccattccat
    27901 cagtagtaga tactttattt gcttttttca tcatcctttt agcagtatct gtatattcaa
    27961 tatggaaaat atggcgctat ccaatgattc gaagttttgg agaaaaagaa caagcagata
    28021 gttcaacaat gcgcttcagg acaaggcacc gattactcgc agtcatcggg ttactacttt
    28081 taacgagcgg atattttgga gctagtcatt ttagggaaat cacttcatgg atgatcagtt
    28141 atcattatct tgatacatta gttttctttt ttcctttttt aatttttttc gtttgtgtgg
    28201 tcggtactta tttgtttttc tgttatacat ttcggttatt tttgatcata ttgagtaaat
    28261 ggaagattta ttactatggt atcaattttt tgataatggg taacacgcaa gttcatttgc
    28321 tcaaaagttg gcgtacaaat tctctgatta cagtcattct cggaatttct ttaatgacaa
    28381 ttggcggcac ggctagtatc tctactattt tatcctacca ggagaaagtt tcctccccga
    28441 tggactatca gtttgatgtt gagacagaga aaaaaatcaa gccgattcta gcagaggaag
    28501 ggcagaagat aactaaagaa atcaccttgc attataaagt cattgggagt atctatagtc
    28561 aaaatctcga agaacctatg tttcaaactg ctaatctgat cacggaaaca caatatcaag
    28621 ccttcagaaa agttaatcca gatttgccga acatttcttt gaaatcacct ggtcatactg
    28681 ttttgcttga tcaaatgcaa actctttttc ggaatatttc attatatgga tctagtattg
    28741 gactgccaga taatcaagaa ttgaagattc aacaaatgct tccaagtgta ttaggtgacg
    28801 aaacaatggt atatctaagt cctgtactga ttgtagatga taccgttttt gaaaaagcaa
    28861 aaggtgtgga ttatcaagta gtcaatgtag atgtatcagg tggaaataat gaaaaaatag
    28921 atgaacgact gagcaatgac ctgtcgataa agtggctcaa tgctgtttat tattcttatg
    28981 atatcgtaaa tggaagtcta caaggagaaa ttagcacaaa gaaacttccg gatgaccaaa
    29041 tgaaggaagc acaatttagc caagaaagct ctcgtttgaa tttctcttcc agctattcga
    29101 aattgcgtgc agttaatcgg cgaatcggta tcaatatttt tgtcacacta tttgtcggga
    29161 tgatcgtgat tattgctact ggtagtattt tgacagtccg gcaattagca gaagcagagg
    29221 aagaaaaaga aaattatcac ctattgacta agctggggat tccacaaaga aggatcagac
    29281 ggatgatctt cgagcaaaac gcacttacct tctttccacc catgatatta gggatcactc
    29341 acgcagtatt tgcaatcaat gtcttcactc agtatataaa aactgccgat tactggttgg
    29401 cttatcttgt gagtggctta ttgatcctta tctatctttt gctttatgtc attacgagtc
    29461 agttatattg tcggattatc gaggaatgat atacggaata agacaagata ataaatagaa
    29521 ctaaattttg aataccattt atttggaata agaggttgtg acacgatttt tgtcacaacc
    29581 tctttatttt ttatattttt taaaagtacg agaaattata aagaaaaaag cagtgatttg
    29641 atgtgctatt tttataaaag ctatgtgaca aaactgttag taaaaaaacg gtttctgtaa
    29701 gctagacaca tgtttctttt tgtcaaaatt agttacactt tgtgtgaggt tatatgagga
    29761 gggaatccaa tgaacaaatg gcgttctaat ccaaaattga attattgggg aaaattcatc
    29821 attcgaacaa ttttttatag tgcagtactg ctgttcctga tttatctgta tcactataaa
    29881 aatattcaag gaggaacttt tatctataac gaattttagg aggaagagta tggaaatcaa
    29941 aacgattatt gaagcaatcg atgattgggg aataaatgaa cctgatcgag ttgcttatca
    30001 ggcggatgag acgcatactt ttggtgaatt gaaacaagca tcagacgcac ttgcttatta
    30061 tttagaaaaa aaggtagaag gcgatggacc aattgtcgtt tttggcaatt tggagtttga
    30121 aatgattgtc tcatttctag gggttgtcaa atctggccat gcctatttgc cgattgaaga
    30181 gcatacaccc aaggagcgta tcctatcgat ctttcgggtg gctaaaccat ctatggtcat
    30241 cagtatcggg gactggatag aagatattcc ttcggttcct gtcataacaa aaaaagaatt
    30301 tcaagaaatc aagaagatac cagtaggatt ttatcccaga aatagcgtaa aaggtacaga
    30361 aaatttttat attattttta cttctggtac tactggagaa ccaaaaggcg tacaaatcag
    30421 tcatgataat ctagtcagct ttgttcaatg gacgatggaa gactttggga tcaagcctgg
    30481 tatgcatttc ttagcccaag cgccattttc ttttgattta tcggtatttt ctatttatcc
    30541 tgcattagtt tctggcggaa tgctgaagcc gttaaataaa gcagttgttc aagactttcg
    30601 tcaattattc gcgacattgc cagccttgaa gttgaatgtg tgggtttcta ctccatcatt
    30661 tatggatatt tgcttgatgg aacctacatt caatggagaa aatgtgccgg aattggacat
    30721 gtttttattt tgcggagaag aattgacgaa aaaaactgca gaaagtctac ttgatcgatt
    30781 cccaaatgca cggatatata atacttacgg tccaacagaa gcaactgtag ctatttcaag
    30841 tattcagatt gaccagcatg tactagatag ttatgaccga ctaccgattg gctacgtaaa
    30901 aaaagacacg aaagtttcta ttgtccaaga aggtaaacct gtttcaaaag gagaaacggg
    30961 tgaaatcatt attgcaggac caagcgtatc aaaaggttac ctgaacaatc ccgaaaagac
    31021 agctgctgcg ttcttttgtc aaaatgactt agcaagttac catacagggg atgcaggtag
    31081 actagatgaa tatgggcttt tattttatga aggacgtatg gatcagcagg tcaaattaca
    31141 tggataccgg attgaactcg gggatatcga acattatctg ctccaagaca accgaatcaa
    31201 acaagctgtc gtcgtaccaa aataccaagg aacaaaagta cagcagctgg ttgcttttgt
    31261 cgtattagaa aacaaaacga aacagccgga ttttcagttg actaaatcta tcaaagaaca
    31321 attactagaa gttgtaatgg attatatgat tcctcagaag ttccattatg tcgatctgct
    31381 gcctcagaca gttaatggaa aaatcgatcg aaaaaaatta acagctgagg tgaatcctga
    31441 atgatgttac ctcatatgat cccttatgca gagccgtttt atttttttct tttagccatt
    31501 gcgcttgtac cgatcgttct atctttattg atatgggaaa aaagattacc agtttatcaa
    31561 tcagcagtga cacttttctt tttatttgtc agctttggag gtaattattg gcaacaggga
    31621 gcggcgctga ttgggtatgt tttgtggcag acgatacttg tatggggcta ttttgtttat
    31681 cggcaaagga aaaatcagac aggatggttt tttgccgccg ttattttagc gataattcca
    31741 ctgtttttaa cgaaagtgac tccttttttt gaacatggaa aagcatcgtt acttggtttt
    31801 ttaggaatct cttatttaac ctttaaatct gtacaaatga tcatggaaat aagagatggc
    31861 atgatcaaaa catataagcc atttcgttat atccagtttc tgctgttctt tccaacaatc
    31921 tcttctggac caatcgatcg ctataggaga tttgaaaaag atcagctcca tccgcctgtt
    31981 cgtgataaat atgttgatct tttgggaaaa ggcgtccaaa atatttttgt cggtttttta
    32041 tataaattca ttatcggtta ttattttggt caagtactgc ttcctgtagt gggacgcatt
    32101 gccttacagc atggtggtat ttcatgggca ttagtaggtt atatgtacgt gtacagtatg
    32161 tatttgtttt ttgattttgc tggctatagc ttatttgcag tcggtacaag ctacatgatg
    32221 ggatatcaga caccaatcaa tttcaataaa ccttttttat catggaatat caaagaattc
    32281 tggaatcgtt ggcatatgac gctgtccttt tggttccgtg attatgtata tatgcgattg
    32341 atgttcttca tgatgaagaa aaaatttttt aaaagcaaga tcgtaatgtc aaatatcggt
    32401 tattttgctt tgtttcttct aatgggtata tggcatggat tgacgtggta ctacatcgta
    32461 tatggactgt atcatgcttg tctgatctgt ctgacagatg catggatccg atttaagaag
    32521 aagcataaag agcagttgcc ttctaacaaa tttacgcatg gcttagccgt atttttgaca
    32581 tttcaagcag tatgttttag cttcctgatt ttttcaggat ttttagataa actttttttt
    32641 agctaacgaa tagtgacata ttaatttata taacaaagga gaaaaggaaa atggaagaac
    32701 aaattttatc aatcttagaa gaaataacag gaacagatga agtaagaaaa aatcgtgata
    32761 ttgatctatt tgatgaaggg ttgcttgatt ctttagcatc tgttcaatta ttagtcgagc
    32821 tagacggaga gctggatatc caagtccctg tatctgaatt cgagcgagag gattggtgca
    32881 caccgaataa aatcattcaa caagcaactg cattgaaggg ttgagtatga aaaagaaact
    32941 ttttgctatt ttcggcccgg ttgttttagc tgttggctta ctgtttgtgt tttttacctc
    33001 ctcctatcaa gtagatatct ctaatccaga aacgattaga cgtgcctctt cttccatgtc
    33061 agtgaacgtg ttgaaaggag atgcgataaa aaattatgca ttatctgaaa aacaatatat
    33121 tccttttttt ggctcaagtg aattaagcag aatcagtcca tttcatccgt ctgttctggc
    33181 agaaaaatac cagcgaaact atcgtccatt tttgctggga gcacccggga cacaatcgtt
    33241 aagccaatat atgatgatgc gttctgcagg agatgctatg aaaaacaaga aagtcgtctt
    33301 tattatttct cctcagtggt tcgttaaaaa tggtgtaaaa actgattact ttaatacgta
    33361 ttattctgaa cttcaaacat acgactggtt gttttcaatg aagaaagtaa cgcctgctga
    33421 tcgctattta gctagaagat tattaacttt ctcaaaagta aaagagaatg atacgttgac
    33481 ggcgattctg caaacgatca aaaaagggaa gctaccttta cctgaatctt tgaatcagct
    33541 gcgcagccaa tggaacatgc tgaagagaga ggatgaagta ttcagcaata ttgggttgaa
    33601 agatcgacag caaaaaatcg atcatgagtc aaaacgatta ccaaaacaat accaagaaac
    33661 agaattatcc attttagcaa atcaaattgg agaacgagaa acgacgaata atccattcgg
    33721 gttgaaaaac gatttttata cgcatcgtat ccgagcccac gagccagagc tcaaacagtc
    33781 acaaaaaaat tgggattatc gtttttcgcc agaattttct gattttcagc tggtcttgga
    33841 tcaattagca aaaaaccata acgaagtatt gttcatcatc ccaccggtta acgagaaatg
    33901 gagcgattat accggactat ctcaagaaat gttacaagga tttgccaaaa agatcaaatt
    33961 tcaattaaat agccaaggat tcaatcgaat agctgatttt gtcaatcaag cgggtaccaa
    34021 ctattttatg gaagacacga tccatctagg ctggaaaggc tggttggctg cagatcaaca
    34081 gatcagaccg tttttagaag aaaatcatat tactgctagt aagtatcatc ttgacgatgc
    34141 tttttttagc aaatcttggc aacatcaaat accagataaa ctacaattaa aataaagaaa
    34201 acaggcgagt gttgctcgct tgttttcttt atttttgaat attctgaata aaagataaaa
    34261 ataccaagtt tgcctgaaca aaaatcataa gcaatggtat aatcacaata tgaatataga
    34321 aatgggggaa aacatttgga tacaaaagaa gaacagctac ttattgattt aacttctgca
    34381 aaaggagtac ctggaaatga agaagaggta agagaagtat tcagagaata tgccaaacca
    34441 ttcgctgatg atatttttta tgacggttta ggcagtgtga ttgccaaaca tggtgctggc
    34501 ggaggcccca aggtctttat ttctggacat atggacgaag ttggttttat ggtaacaaaa
    34561 ataaccgaaa aaggattctt ggaattccaa actcttggag gttggtgggg gcaagtcatg
    34621 cttgctcagc aagttgaaat caaaacacgt gaagggaaaa tcgtccacgg tgtgattggt
    34681 tccaaaccac cacatgtttt aacacctcaa gtaagaaata aaccttatga aataaaggat
    34741 atgttcattg atattggcgc atcaagccaa gaagaagcca aagagtgggg catacgtcct
    34801 ggagatatgg tcactccata tattgaatac aaacgaatga atggcagtaa atatttactg
    34861 gcaaaagcat gggataatcg tatcgggaca gctgtttctc tgcgagtatt agagaatcta
    34921 tctaaagaag cacacccaaa tgttttattc gcaggaagcg atgtgcaaga agaagtaggc
    34981 ttgcgaggtg ctcgaacaag tacacacctt gtaaatcccg atattgcttt tgctttagat
    35041 actggtacag caggagacac tccaggaatg acaccaaaag aagcagattc gattttagga
    35101 aaaggcccac agattttgat ttttgatgca tctatgatcc cgcataaaaa attattgaat
    35161 tttgttattg atgtagcaga ggaaatggat attccattcc aatatacagt gatttctggc
    35221 ggaggaactg atgcaggaca aatgcatttg acaagagatg gtgttccgtc tgtagccatt
    35281 accgttcctg ttcgttatct gcattcccat acatcagtga ttcatgaaga tgattatttg
    35341 aatacagtga aactagtcac agaattagtg aaacggcttg atagtgaaac agttgaaaaa
    35401 attcggagtt atgaataatg aataatagaa tacctatttc tgaatatcgg aaaaaagcac
    35461 gagtttcttt ggaaaatcaa tggggaatca atacttggct tgttttctta tctataatat
    35521 ttacgagcgt catccagaac ttttttgacg gtttcagtcc ttttccggaa gaaagcatgc
    35581 agcagcactt attgagtttt ctagtcgata atttactttt attcgcattc aactatgcat
    35641 tgttttacat tgcgctagta gttgtacggg gtggcagacc aaaaagtaac cttttatttt
    35701 cagttttcca aagaaagtat tttggttcga tacttggcat caatttgatc aattcagtca
    35761 tcaactggct actcaacagt ttaatctttc tgcccatgtt tttaatcagc ggagtgagta
    35821 cttatatgca gctgcttttc agttcaaatg cggtacctac gggtgtcatg ccagaagatt
    35881 ttcttgatat cagctttgtt ttatcgatga tagggatgat ttttgtttca gcactcatca
    35941 tgagtattgt tggcggttta ttccaatttg ctgcatggac aaagttcgac tatcctgatt
    36001 tgtcggttat tcaatgtttg aaatatggct ggtttttatt gaaagataga attggtacgt
    36061 atattttgtt gcagctgtct tttatcggct ggtatttgct aggagcaatc gctttgttca
    36121 tcggtctttt gtgggtcatt gtttatgtga atgtgtcagt tgcagaattt tatgaacaag
    36181 cacggattga aaaaggaggt ccagacgcct attttactta gcatgtaagc agtttattca
    36241 tcaaaaaaat aacttttgtg gtaggataaa tctttgaggg ggaatgtacg atgaaattaa
    36301 ctgttttagg atgcttagga gcgtatcctt ataaaaatca agggacaaca ggttatttgc
    36361 ttcaatctga cgggttcaat ttgttgatcg atgcaggtag tgctacgctg atcaaattac
    36421 aagaacacct tgatccactt gatctagatg ctgtgatcct tagccattat catcatgatc
    36481 atattgctga ccttggtgta ttacagtatt actggcaact tcatcctaag agaaatccgg
    36541 agacattgct ttcaatttat ggacacacaa aagattccat tcactttgaa gaattgacgt
    36601 tggaaaatgt ctcaaaagga catccttatt ttgaagctga agaattaaaa attggtcctt
    36661 ttctgattac ttttatggaa acaatccatc cagtagtatg ttacgccatg cgtatcgtag
    36721 aagaaacaac ggggaaagta ttcgtattta caggtgattc aggttatttg gaaagtttcg
    36781 ctgattttgc gaaagatgct gatttgtttc tagcagatac ctatcttttt gaaggaaatg
    36841 aacatcatca tgcccatttc acttcaaaag aagctggaga acttgcgaaa tcagctaacg
    36901 taaagaaact tgtacttaca cacctacctc agtttggtga tttagaacaa ttgaaaaatg
    36961 aagcgcaaaa ggcagcaggc aaagggattg atatagaact tgctgcagtt gacaaagtgt
    37021 ttaacattta ggaggaagaa catgattttt gtaccaaatg aaaaccacga cccaagaatc
    37081 aatttagcaa ttgaacaata tttgctgcaa gaaatgcctt tagatgaacc tattttgctc
    37141 ttttatatca atgaaccttc aatcatcatc ggcagaaacc aaaatacgct tgaagaaatc
    37201 aatcgagatt atgtggaaga aaatggcatt catgttgtcc gtcgcttaag tggaggcgga
    37261 gctgtctacc atgattttgg aaacctgaac tttagtttta tcatgcctga tgatggggat
    37321 tcattccgtg actttgcgaa agtaacacag ccaatcatcc aagcacttca tgaattgggt
    37381 gttgctgggg cggaattgaa aggccgaaat gatctagtca ttgatggcat gaaattttct
    37441 ggcaacgcga tgtatgctac caacggtcgg atgtttgctc atggaacaat tatgttcgac
    37501 tctgatatca atgaagtagt caatgcatta aaagtaaaaa aagacaaaat cgaatcaaaa
    37561 ggaatcaaat cgatccgttc tcgtgtaacg aatatcaaac catttcttcc agaagaaaag
    37621 caaaaaatga caacagaaga atttcgtcaa gaaatcttgt tgaaaatttt cggcgtagag
    37681 tcagtagaag aagtaaaaac gtacgaattg actgatgaag attggaaaaa aatcaatcga
    37741 atctctgagg aatattatcg aaattgggat tggaattacg ggaagtctcc agatttcaat
    37801 ttctctcgcc aaaaacgttt ttctatcggt tcgattgaag tccatttgaa tgtctcagaa
    37861 ggaatgatca aagaagcaaa aatctttggc gatttcttcg gactaggaga tatctctgac
    37921 gtggaaaaaa aattggttgg acagaaatat gataaagcat ctctatcaaa aatagtcagc
    37981 caaattgatg tgaagaaata ttttggtgcg atagaaccag aagaattgct taccttactt
    38041 tattgaaaat aaaaaatagc ggaatccaca tatatggatt ccgctatttt ttatacagga
    38101 ttcgggtaat ttcgagagag ttgaacagtg atccgatcaa tgaaagtatc tttttcctgc
    38161 gttagtgttc ctgtgtaacg atccgctacg tctttcatca tcattaagtc aaaacgttcc
    38221 tgatcatcta attcttctgt gatgcctcga ctaaataggt ttgtatcgta atgtgcacta
    38281 tgttcgcaac aaatgacgaa atgttcctct tgttcgtgta tcgacaaata aatttttcga
    38341 tacagtggat tttcgatggc atgagtttct ctaaaggaat gctctaaagc gtggatcaaa
    38401 agttgagcca gatcgtcatc gttgatagga agttcttcgg gaagatctgc ttggaaggtt
    38461 atctgaatat tccgtttggc agctaacttc tggtaacgcg ctaagataag atttgtcacc
    38521 tggtggttgc aaaaagaaca cagcatttcg aaattttttg cttcttctaa tatcttttcc
    38581 acatagtttt tagcttttgt ttggtccgta tgcattaaat cttgcagatt ctccatctct
    38641 tggacaaatt ccaggcgaag tgtatttact tcttggatat gctgtcgaag ctgctcataa
    38701 tgttgctcca acaaatcatt tttgattttt aagaaatcta cttgtctccg atctttgtcg
    38761 gtatttaaga tgtgatcgat tagattgtag ctgataataa cgattagaat gataatatat
    38821 aaaatcgtag accaattgat cgttgtttga tagataccta atgccgtttg gatgtaaatc
    38881 aagcaatgga taatggctac caagacgatc caaggtgtac aagctacata aaaacggtta
    38941 ttcttatatg cttcgccaat gcatgcaagt gaagtgacta aagtgcttat aacactagca
    39001 atattagcaa tcggcattaa ttcaggaagt tctgcaggag taaaagttgc ataaagcaga
    39061 acgccgataa aaatcaaaag ttggaacgta caaaaaattc cgtaccattt tttatagtaa
    39121 aacattcggc tccaatagta gcagatgatg aaagctgacg ttaagataat aaataaatga
    39181 gataaaaaag aatgaacgaa tggttcaaaa agaataccac ttaaaatatc ttctgataca
    39241 gcttcaaatc ctaatgccaa agcaaagcaa cttaagagaa taagtgagta ttcaagacgt
    39301 ttttgtttat acatcaagta gatcgtatag aaaaaggtcc ctatagcgat aaaaacagcg
    39361 attatcatcg tcaatacttg cggcactgat tgtgaataaa taaaactaat caatggtcca
    39421 gttgttccta gataaacttt cggtggcagt ccagcatagt tctgataagg agatgagact
    39481 gtaagggtca atttttttcc gatataattt gctggtaaat ctatcacagc caatgagagt
    39541 ccgggattgc tttcttcctg ataatctttc cgttggtata aaatcttttc gcctagatat
    39601 acagtaatcc attgatggtt tcctttgatt agtaaatttg cttcgtccaa cggtttttca
    39661 agtgtcgttt ccataatgaa tgtttcgtct ttatccacgg taggaatcgt acgagtgtac
    39721 ttgctgtcaa acttaaaatc aggatcatct tttgtataga aaacccacga atcttttatt
    39781 tctttcattt gattgctgtc cgcaggagaa aaaataaaat aaaagaaata agcaattcct
    39841 gttaaaaata acaatgataa tataatgatt atgctccact ttatacg
//
LOCUS       DADGHT010000012        39854 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.012, whole genome shotgun sequence.
ACCESSION   DADGHT010000012 DADGHT010000000
VERSION     DADGHT010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.012"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..369
                     /locus_tag="JX887_000562"
                     /pseudo
     CDS             1..369
                     /locus_tag="JX887_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(495..1574)
                     /locus_tag="JX887_000563"
     CDS             complement(495..1574)
                     /locus_tag="JX887_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAX1256575.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(1677..2117)
                     /locus_tag="JX887_000564"
     CDS             complement(1677..2117)
                     /locus_tag="JX887_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAX1256576.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(2174..2584)
                     /locus_tag="JX887_000565"
     CDS             complement(2174..2584)
                     /locus_tag="JX887_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAX1256577.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(2764..3198)
                     /locus_tag="JX887_000566"
     CDS             complement(2764..3198)
                     /locus_tag="JX887_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAX1256578.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(3298..4146)
                     /locus_tag="JX887_000567"
     CDS             complement(3298..4146)
                     /locus_tag="JX887_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAX1256579.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            4535..6301
                     /locus_tag="JX887_000568"
     CDS             4535..6301
                     /locus_tag="JX887_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAX1256580.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            6403..7662
                     /locus_tag="JX887_000569"
     CDS             6403..7662
                     /locus_tag="JX887_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAX1256581.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            7809..9110
                     /locus_tag="JX887_000570"
     CDS             7809..9110
                     /locus_tag="JX887_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1256582.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            9113..9964
                     /locus_tag="JX887_000571"
     CDS             9113..9964
                     /locus_tag="JX887_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1256583.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            9977..10792
                     /locus_tag="JX887_000572"
     CDS             9977..10792
                     /locus_tag="JX887_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAX1256584.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            10943..12109
                     /locus_tag="JX887_000573"
     CDS             10943..12109
                     /locus_tag="JX887_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1256585.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            12339..12986
                     /locus_tag="JX887_000574"
     CDS             12339..12986
                     /locus_tag="JX887_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAX1256586.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            13070..14014
                     /locus_tag="JX887_000575"
     CDS             13070..14014
                     /locus_tag="JX887_000575"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAX1256587.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            14149..15600
                     /locus_tag="JX887_000576"
     CDS             14149..15600
                     /locus_tag="JX887_000576"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAX1256588.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            15621..16457
                     /locus_tag="JX887_000577"
     CDS             15621..16457
                     /locus_tag="JX887_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAX1256589.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            16457..17116
                     /locus_tag="JX887_000578"
     CDS             16457..17116
                     /locus_tag="JX887_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAX1256590.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            17242..17931
                     /locus_tag="JX887_000579"
     CDS             17242..17931
                     /locus_tag="JX887_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256591.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            17937..18893
                     /locus_tag="JX887_000580"
     CDS             17937..18893
                     /locus_tag="JX887_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAX1256592.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            18937..19449
                     /locus_tag="JX887_000581"
     CDS             18937..19449
                     /locus_tag="JX887_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1256593.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(19705..20253)
                     /locus_tag="JX887_000582"
     CDS             complement(19705..20253)
                     /locus_tag="JX887_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1256594.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(20342..21523)
                     /locus_tag="JX887_000583"
     CDS             complement(20342..21523)
                     /locus_tag="JX887_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAX1256595.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGLGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(21759..23267)
                     /locus_tag="JX887_000584"
     CDS             complement(21759..23267)
                     /locus_tag="JX887_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAX1256596.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            23426..23617
                     /locus_tag="JX887_000585"
     CDS             23426..23617
                     /locus_tag="JX887_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256597.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            23820..24737
                     /locus_tag="JX887_000586"
     CDS             23820..24737
                     /locus_tag="JX887_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAX1256598.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            24730..25803
                     /locus_tag="JX887_000587"
     CDS             24730..25803
                     /locus_tag="JX887_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256599.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            25951..26469
                     /locus_tag="JX887_000588"
     CDS             25951..26469
                     /locus_tag="JX887_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256600.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            26450..26842
                     /locus_tag="JX887_000589"
     CDS             26450..26842
                     /locus_tag="JX887_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAX1256601.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            26918..27853
                     /locus_tag="JX887_000590"
     CDS             26918..27853
                     /locus_tag="JX887_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAX1256602.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            27986..28765
                     /locus_tag="JX887_000591"
     CDS             27986..28765
                     /locus_tag="JX887_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAX1256603.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            28758..29075
                     /locus_tag="JX887_000592"
     CDS             28758..29075
                     /locus_tag="JX887_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAX1256604.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            29319..30929
                     /locus_tag="JX887_000593"
     CDS             29319..30929
                     /locus_tag="JX887_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAX1256605.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            31086..31934
                     /locus_tag="JX887_000594"
     CDS             31086..31934
                     /locus_tag="JX887_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAX1256606.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            32165..32644
                     /locus_tag="JX887_000595"
     CDS             32165..32644
                     /locus_tag="JX887_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256607.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            32677..34905
                     /locus_tag="JX887_000596"
     CDS             32677..34905
                     /locus_tag="JX887_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAX1256608.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            35034..36677
                     /locus_tag="JX887_000597"
     CDS             35034..36677
                     /locus_tag="JX887_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAX1256609.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(36750..37295)
                     /locus_tag="JX887_000598"
     CDS             complement(36750..37295)
                     /locus_tag="JX887_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAX1256610.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(37318..37803)
                     /locus_tag="JX887_000599"
     CDS             complement(37318..37803)
                     /locus_tag="JX887_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAX1256611.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(37793..38605)
                     /locus_tag="JX887_000600"
     CDS             complement(37793..38605)
                     /locus_tag="JX887_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAX1256612.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(38744..>39854)
                     /locus_tag="JX887_000601"
     CDS             complement(38744..>39854)
                     /locus_tag="JX887_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAX1256613.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        13176 a         7200 c         7809 g        11669 t
ORIGIN      
        1 tccagaagaa aaaccagatg tgactccaga accagatacg gacgcaagag accaaggaat
       61 accagaaaaa ataaacaaaa aaacaattca agaggatgga aaaaaagaga gtaaaaaatc
      121 aaatctagca attctaaaaa taaatgaaga gcagctgaat aaaaaatcac gaatatttga
      181 tagcgcccaa tcagctgaaa ccttaaaaag tagcaaggat acaacctttg ctgtcctgaa
      241 acgaaaaata aacagctacc aaaatccgga gagtcacaaa acaaagttat actgtggagc
      301 ggaatcattc tattaagtat agcaacaatg ctttctgcaa aaagatttaa acaaaacaga
      361 tctctctaac atttgaataa tgtctgtgaa cgcatttttc aaataaaaag aaatatccag
      421 aaaatgaccc caaaatacca gattgaaatc tgatatttgg ggtcgttcat actttatctt
      481 tcttcatatt tattttaagg gatatctgtt tcttttggaa gatggttcgg gatctttttc
      541 actttcaata catctaaaaa gaaggtaaag atcggaatgc cgacaatcaa gccccaaacg
      601 ccaaagaacc gttcgctaac aagtaagacc acaaatgtat aaaaaatcgg cagttctgtt
      661 ttgctggaca tcaacttcgg attcagcaca taagactcaa ttagatggac aatcaaaatc
      721 gtaatcagga tataaacaac atctcggatg cctccttggg aataagctat gaaagataga
      781 ggaatacaag aaatgataac acctgctact gggatcagac ttaaaatgaa aatcatgatc
      841 gctaaactca gcagctgatg aaagccaaat acagccaagg cgattgtagt gagcaacgta
      901 tttaaaagag cgacaacaaa ttgagcttct aataccaaac caaatgtatt gacaaactta
      961 tcggcaaaat agtaaatatc ttgaaagaac caagaaaatt cactttttaa aaacaatctt
     1021 gagaatacaa ttgttttttt cttttcaatc ataaaaaaga aacttaagat gaatgacata
     1081 gcaaacgcca ctgccatttt tcctatatcc tgtaaatagc caagcgcaat cgaagcgcca
     1141 ttttgaagct gttcaaaaaa atcgtttcgc tcaatataag tatggatata ttgtaaaaca
     1201 ggatctgcat cttttggctg atgctcgtaa aaattaataa cggactggat catgtcaaat
     1261 gtttgatgaa taagcatcgg gatatacttt gtgaatgcca gatagataag gtaaacgatc
     1321 agtgtataaa tcatgatagc taaaacacct gtagggattc ggacaaatcg ctgaatgatt
     1381 tgaacaagat gaatcatcaa ataagtaaag ataaatgtga gcaaaatggt tgtaatcata
     1441 cttctaacta agaaaagaac aaaaacgaca aataataaaa cagtgagacg gcgtattttt
     1501 tcattcgcca aaaaacgctg ataaacggtc aaatcgacaa cctccaaata acaaaaaata
     1561 aacacgttat tcattatatg atggaatatg aaaataagaa agagcaaaaa gaaaaaccgc
     1621 taaatgacgt tatcttatga gttggttttc ctcataaaat cgttcatcta gcagtttcag
     1681 ccctttttct ggtcttgatg aaaattatct agcatttttc gggtcagatg ttgcagtgta
     1741 tccaattctt cctgttcaag tggaagataa gacttgatct tttgtggaat accttctgct
     1801 tgtttttgca acgcagcacc ttgagcagtc agcgtaacat ttacgattct ttcatcaccc
     1861 gtttcacgct gacgattaat ataatttttt tctgctaact tttttagtaa gggagtcagc
     1921 gtaccagaat ccagacacaa atcatttcct agctctttca ctgaagtctt tttcttttcc
     1981 cataaaacta acatcacaag atactgggta taggtaagat tcagcggctt gaggagggga
     2041 gtgtagtgtc taatgatttc tttagaggcg gcatataaag gaaaacatac ttgattaact
     2101 aaatatagat cttccatttt tccacctccg ctgttttact atagtgtatc atagcggatt
     2161 tacacaaaaa agtctattca ctaactgctt tcagagtaac ttctatattt ccagctgtag
     2221 cttttgaata cggacacact ttatgcgctg cctctaataa ttcttgcgtt tcttccagag
     2281 aaagaccttc gatagatcct tcaatctcta cacctaagac aaagctcgtt tcactttctg
     2341 aataaaggga aacttgtgca ctgacagtag aagccccaga gatatttttt tgctgtttga
     2401 tcaattctaa tgcactgtta aaacatgcac tgaaaccagc tgcaaacaat tgttcagggt
     2461 tggttgcatt ttcgacgcgt ttaccaggag ctgcaatatt caattcgaat gtacgatcgg
     2521 gattatgcac ttctccagag cgtccgcctg tgttgatcat tttcgtagaa tacatttttt
     2581 tcataaaatt accaccttta attatatttt atacaattga attttacaca atataattgt
     2641 ggaaagcaaa gaaatggatt ggcataagat aaataagaga aagcacatga aacagacgcg
     2701 ctttctcgaa tagcaaacat atacaaaaaa tatcagagac aaaaaataat ctcatcataa
     2761 acattacata tatttctcaa aaagttgttt tctttcttca aaaattactt cacgatggac
     2821 ctgatgaagc atccataaat aaccaaaagg atctctgaac attgagttag tcacaccaaa
     2881 gtccatcatt tctgtcattt cttgaatctc tacacagcca tttcgtaatg ctttattatg
     2941 tgtgtcctcg atatcagaga cgatgatatt gaaccagatc gtatttggat gttcagcagt
     3001 aggagcagtc aaaccaagag acgtgttttc atccagcata tggaatctcg taccatacaa
     3061 ggtaaaaatg acttcattat tgcctctagg gtaatctgtt gcctcaatca gttgtatttc
     3121 atcaaagatt gtttgataca gttctagtgc tttcaaacta tcatttaata caaaatcgat
     3181 ttccgttcct ttatgcataa agatctcctc tccttttcag tcgaacagtt actagattct
     3241 tttattatac cagctaaaga aaacgcattc aaaaaaatag cggatttact taccaactca
     3301 ttcgattgga tgataagtaa atccgcgtcc cattacttct gctacgctgc tgacaatgac
     3361 aaaggcactt ggatcgattt cttctatcaa tggtttcatt cgggaaaatt catgatcagt
     3421 cacaacgatc aataaaacct cttttgactt tcgattatac ccgccttttg cctctagcag
     3481 ggtaaggcca cgtccaatct cagcacttaa gcgaaggcgg atgtcttcca aataatgttc
     3541 actcatgacc ataacagatt tctttcgatt gatacctgtt tcgatataag tcatgacaat
     3601 tgaagtgatt gcaatagata aaatagcata aagaaactct tctattccaa aaataaacag
     3661 attaagagaa acaacgaatg cgtctgtaaa aaataagcca atcgaagtat tcaagtggaa
     3721 atatttttta aaaatgaggg gagggatcgt cgtaccgccg ctagaagagt tgtttttata
     3781 taaaatcgca actcctaaag caaaaatcgc acttccaaaa atgacagaca acaaccgatc
     3841 tgaagtaatc attgtttctg gaactattgc aatgattaaa ggaaaaacca agcttccgaa
     3901 aagtacttta aaaaagggtt ttttacctaa aaatagaaga gctagtacca acataacgat
     3961 attcaacact aaaataacta tagctcggtc aaagcctaaa gcagcttcca gtaatattcc
     4021 tagaccgctg acacctccag cagcaatatg atgaggccct aaaaacatat tgatagcgac
     4081 tcctaatatg aagagggcaa aaataatctt aatgtatgtc catataaatt gtctcgtttc
     4141 tttcatttat tcacttcctt aattcattaa taatactctt atcttattat aacttacttt
     4201 tcaccttaag ttaactttaa ttaataaaaa aattaggcta gtctaaatta ttatgtttca
     4261 ttcttctaga atatacttct acgccaaaaa ctgttaaaaa acttttactt tagaaaattg
     4321 gagaaattga tcgcttaaga taaattcagg acactaaata gtacaggaag tagactaaaa
     4381 cttttaaaag ttttaagtct atctatttgg caagtttaaa aaataaaaat tcggtatcaa
     4441 aaaactgtta ccgataacat ttttgaaagc gttgtctttt gcttctctat cacttatagt
     4501 gatgacgtca tattaaaaca caaggaggaa atcaatggat acagctgcaa tttatcatcg
     4561 accggaaagt gaatatgcat ttctatatac gaatacaaga tttcgtattc ggcttcgtac
     4621 taggaaaaat gatatcaaaa aagtatatgt gctatgtgga gatccatata ccataacaac
     4681 tgaaaaatgg tatcaaaaac aacgaccaat gaaaaaatgt ctaagtacca atgttcatga
     4741 ttattgggaa attgaagtga cgagcgaaac aagtcgctta cagtatgcgt tccatgttgt
     4801 tggggaagat aacacggact gtttttacgg tgatcaagga atttttcctt atcgagaaaa
     4861 tgtgattact gaaccaaatt tttattttcg aataccttat tttcatcaaa tcgatcgatt
     4921 cactattcca gaatgggtaa aagaaacagt atggtatcaa atttttcccg aaagatttgc
     4981 aaacggggac aaagcaaatg accccgaaca cactttacct tggggaagta aagatccaga
     5041 ccgagaagac tttttcgggg gagatttgca aggtgtgatg gatcatttgg attacttgac
     5101 ggaccttggc atcaatggca tctatttttg tcccatattt aaagccacat ccaatcataa
     5161 atacgatacg attgattatt atgaggtgga tcccgctttt ggcgataaaa aacttttaaa
     5221 aaacttgatt gatgaagcac ataaaagagg gatacgtatc atgttcgatg ctgtattcaa
     5281 tcatatgggt gtccattcac cacagtggca agacgttctc aaaaacggag aaaaatcgat
     5341 ctataaagac tggttccaca tccgtttttt cccagtagat tcttatcaga tgactgactt
     5401 accagaaact gctgaaaata tcccatatga tacttttgct tttactccat tcatgccgaa
     5461 actaaataca gcaaatccag aagtgcaaaa atatttgctg gatatcgcaa cttattggat
     5521 aaaagaattc gatattgatg gatggcgtct tgatgttgct aatgaagtcg atcatcattt
     5581 ttggaaaaaa ttcagagaag cagttacaga aatcaaacca gacatctata tccttggaga
     5641 gatttggcat tcctctcaag cttggctgca aggggatgaa ttccatgcag tgatgaatta
     5701 tgcatttaca gattcgatta aagattattt tgcaaaaaag aaaatcacag cttcacaaat
     5761 ggtcagtgga atgaatcatc agcaaatgct ttacagagat caggtgaacg aaggaacatt
     5821 caacttatta gattctcatg atactgccag gatcttgacc ctttgccaag gtaacaaaga
     5881 attgatgaag tctgtgatgg cctttatgtt tcttcaaaaa gggtctcctt gtatctatta
     5941 cgggacagaa atagggatga ctggtgaaga tgacccggat tgccgcaaat gtatgatatg
     6001 ggagaaggag gaacaagatc tagagctatt cggttttata aaagaacttg tttctctaag
     6061 gaaacagttg tctaagatta tttctgaagg ttctactcag tggctaatag taaatgatcg
     6121 tgaagataag ctctatttca cacggaaact agagggacag atcatctatg tttactttaa
     6181 tcagtcaaaa gaaccttggg tagtagaaca ggaaaatgag gtgattctta gtcaaaattg
     6241 tcagttgtta gaagacggga aagcagagat acgacaatac ggatttttga tcatgtgttg
     6301 aaaactgtta ccggtaacaa caagaaagcg tttgcaaatg aagatttgtg cccattataa
     6361 taagggtgta acagcacgtt gaatacaaag gaggaaatga agatgaaaaa aagaagtgtg
     6421 aaacagttgg gtttagggtt aatctcttta ggaatcttag gcggattagc ggcttgtggc
     6481 aatggtaact cttcagcaga aggggaagcc gatgaaggaa aaacgttaac agtttccgtt
     6541 gattctggat ataaagatta tataaacgaa ataaaaaaca ctttcgaaaa agaaaacgat
     6601 gtgaaaatca agctagtaga aaaggacatg ttcgatcagt tggaatcatt agcgttagat
     6661 gggcctgctg gaaagggacc tgacgttatg atggcagcat atgaccggat cggtgcgtta
     6721 ggacagcaag gacatctggc ggaagtaaaa ctgggaaatg aagcagctta cgatgaaaca
     6781 gacaaagccc aagtgactta tgatggaaaa atctacggag aacctgcagt aatcgagacc
     6841 cttgttttgt actataacaa agatttagtc gatacagcac catcaacgtt taaagatttg
     6901 gagaatctat ccaaagacag tcgttttgct tttgagtcag aagcaggaaa aaatacagga
     6961 tttttagcta aatggactga cttttattat tcctatggtt taattgcagg ttacggtggc
     7021 tatgtatttg gtgatgatgg cacaaatcct tcagatatcg gtttgaataa tgcaggtgct
     7081 gtagaaggaa tctcttatgc aacagattgg ttcaaaaatg tttggccaaa gggaatgcaa
     7141 gacataaaaa gtgcaggaga cttcgccagc cagcaattca tgtccaataa aactgcagca
     7201 atcattgacg gtccatggca agcgcaaaca tacaaagaaa acaatatcaa ttatggtgta
     7261 gccaaaattc ctactctaaa taatggacag ccttatcaac cgtttggcgg aggaaaagga
     7321 tgggtagtca gcaattatgc taaaaacaaa gacctctctc aaaaatggct tgattatgta
     7381 acgaatcagg aaaatcaaga aaaattcttt gaaatggtaa atgaaatccc tgcaaaccaa
     7441 caagctaggg aaacagcaaa ggctaaaaac gatgaattaa caacagctgt gattgaacaa
     7501 tatgaaacag ctcaagcgat gccaaacatc ccagaaatgg gcgaagtttg gacaggtgca
     7561 gaaaacttga tgttcgatgc agcatcaggt tcaaaaacac caaaagaatc cgcagatgaa
     7621 gcagtaaaaa caatcagtga agccatagaa caaaaatact gattaaaatg ataaccgtcc
     7681 atttttataa aaaatggaac aggtgcttca gataaaagtg gcaagagcga gatggaaaat
     7741 tatcttgctc ttgttgccat tatcttaaaa gcagtttgcg gtttagcaag tttagagggg
     7801 gcattcagat gcagcaagat aaaacaagca atatcaacga aaaaaaaatc acgctttgtt
     7861 cacttattcc agggatgggg cagtttgtaa atggccaagc ttttaaaggt atcgtttttt
     7921 tcgccatatt cgtcctattc attggtcaga tgcttctggg cggatttcat gcattggtag
     7981 gattggttac tttgggaagt ataccaatgg aagatcattc attatttatt ttgattgaag
     8041 gcactttgca attcatcatt acaatcattt tcttgatttt ttacggtttg aatcttttag
     8101 acgcttatcg agtagcgaag atgcgtcaag agggcaaaaa aatcaatcgg acgatgaagg
     8161 aagtcataca taatataggt gatgaaggtt ttccttatct attgacactt cccgcttatc
     8221 ttctcatgat ttttacgatc attttcccag tcctagttac attgttcact gcatttacta
     8281 attatgactt caatcatatt ccaccagcca gtttaattga ttgggtaggg gctaaaaact
     8341 tttttagtat cttcttttta agctcatatc gtaatacttt ttttgcagtc ttttcgtgga
     8401 ccgtgatttg gactttatgt gcaacaactt tgcaaatcac ccttggtatt ctcacagcgg
     8461 ttgttgctca ccagaaattt attaaattca aacgtatttt cggtatcatt ttcttattac
     8521 catgggcggt cccagctttt attactatca tgagtttttc gaatatattc aacgatagcg
     8581 taggtgccat caatactcaa gtgattcctt tcataaacca gcttcctttt gtagatatca
     8641 gtgcaatctc ttggaaaacg gacccgaact ggacgaaagt agcaattatc ttagtgcagg
     8701 gctggttagg atttccctat atctatgtga tggttacagg aatcttacaa tcgatttcag
     8761 aagacttata tgaagcagca aaaatcgacg gagcaaatgc atggcagcgc ttttcaaaca
     8821 tcacgcttcc tgctgtcttc ctagtggcag cgccaacatt tattacacag tatacgggga
     8881 atttcaataa tttctccatg atctatctgt ttaacaatgg cggtcccgga agcgtaggcg
     8941 gaggagctgg ttctactgat attcttattt cctggatcta taaacttacg actggaactt
     9001 ctccgcagta ttctatggct tcagcaatca cgttgattat ctccgtcatc gttatctgtg
     9061 tgtcattgct ggtatttaaa aagacaaatg cgttcaatat gggggattaa caatgaaaaa
     9121 atttcattcg agtgctcgat tccaaaaacg actttctcac ttttttactt acttttttct
     9181 tttaatactg tcagtcatta tcatctatcc gcttttgatc acagcaagta ctgccttcaa
     9241 gtcaggaaat attgcagctt ttagtttaga tctttcaagt gactggactt taggaaactt
     9301 tactcggcta ttcagtgaaa cactttacgg gacttggtat aaaaatacat tgatcatttc
     9361 tgtcctaaca atgatcgtac aagtgactgt agtaactttg gcgggctata cttatagtcg
     9421 ctatcgtttt atcggccgca aatcaagttt gatgttcttt ttagtgattc agatggtacc
     9481 gactatggca gcattgactg ccttttatgt catggctttc ttattagaag cgctcgataa
     9541 gtactggttc ttgacaatga tctatatagg cggtggaatt ccaatgaata cttggctgat
     9601 gaaaggatac tttgacactg taccaataga tttagatgaa tctgctaaac ttgatggggc
     9661 agggcatttc aggatttttt tccagattgt attaccgctt gtcaaaccga tgctcgccgt
     9721 tcaagcatta tgggctttta tgggaccttt tggggatttc atgttagcta agttcctgct
     9781 tcgaacacct gaaaatcaga ctgttgctgt cggcttacaa acatttattt ctgatgtgac
     9841 aaaccaaaga gtctctcttt ttgctgctgg ggcaattttg attgcactac cgatttgtct
     9901 attattcttc tttttacaaa agaactttgt taccggcctg acatctggcg gaacaaaagg
     9961 ataggagcag agtatcatgc aaacatttcc gttaaactat ttttccgcat tacgtacgcc
    10021 aactcaagtg tttgcgggac gcaaactatt atcatggcct aaatttttct tgatatttgt
    10081 atttttagtt tccttgatgg tcatgcctgt gactcttttt tatgccaatc agatccaagc
    10141 gattccatta gaacaatttc tatccgttca ttcgctgatc gatgaacaag gaacccaaaa
    10201 attttctgaa cttgaattat ctgaaactgg gttacaagca tcgcaacaaa cgatagctgt
    10261 gacccctgaa attttggtag gtgtgtcttt atctgagaaa caacaatccg atcatggaac
    10321 ttttattgat tttgagaagg aacaatgggt gatccaacaa aaggataaat ctggtatacg
    10381 ccgctatacg atgaattata gcccatcttt ccaaccagat tctgtacgta cgcccgaaga
    10441 tttccaacga tttttagaaa gagaatttta tgccagtaat cgtccaacaa tcattttatc
    10501 ttatagttta agtcttggtc ttgtcctatt tgtcatgacg agtctcattt tattcggggc
    10561 ttcctttttc ttgtggatga caagaaaaag ccaactttca tccattcata cattcaaaga
    10621 gagtgcaaat ttgatgctga atgttatggg aataggttcc atggcagcag cagttgtagg
    10681 gtttatccac tttgacttta tcttgatgct aagtgtccaa acaacgataa ctgtcttgct
    10741 gcttttatgg gtttttgtca aaacaagatt caaagataag cgtgtcgaat gacaagttta
    10801 agcgatttat gcgacaatga atgtgaaaaa aatgaaaaat aaagtagttt ttgaaaaatt
    10861 tctgaaaaaa ttaaacttct tagttgattc ttttcttttt tagtattaac gtaatagggt
    10921 agttttttta aggaggaaaa tcatgttaga gaaaacttta tacaatcaat tattttcacg
    10981 ttctttctcg ctccctgtcg aagtaaatta ttgggacggt acaacgaaac aatacggaga
    11041 tacggacact cctccccaaa tcaaaatcaa tatccatgaa gaaatcccaa tgaaagagat
    11101 tacaagtaac gcttctttgg cactaggaga agcctatatg gatcatcgaa tcgagatcga
    11161 gggaagtatc caagcattga tcaacgatgc ttatcagcaa gcaaacagct ttttacgagg
    11221 aaaagattat ctaaaatggc tgccaaagaa agaaaaacat acgaaacaaa aaaacaaaga
    11281 agatatccat gcgcattatg acttaggtaa cgacttttat aaactttggc tagatccaac
    11341 tttgacttat tcttgtgctt atttcaatac acctgaagat acgttggaac aagcacaaat
    11401 caataaagtc catcatatct tagacaaact ctttatcaaa gaaggcgaaa cgttgcttga
    11461 tatcggttgt ggctggggaa cattgatgtt cactgctacc aaagagtata atgtcaaggc
    11521 aactgggatc acactaagtg aagaacaata cgatttgatt accaaaagaa taaaagaaga
    11581 acatttagaa gataaatgcc gtgtattatt aatggattac cgcgaactaa aaggcgaaac
    11641 gtttgatcat atcacaagtg taggtatgtt cgaacatgta ggttctgaaa atcttgaagg
    11701 ttatttcaaa gtggtaaaag atttattgaa accaaaagga acagctttga tccatggaat
    11761 cagccgacaa caaggcggtg cgacaaatgc ttggatcaat aaatatattt tccctggcgg
    11821 ttatgtccct ggtgttactg aattagttga taatattaca aaaaacgatt tgcaactgat
    11881 tgatttggaa agcttacgtc gtgactacca attgacatta gaacattgga caaagaattt
    11941 tcatcaagtc caagatcaag tcacgaaaga aatgggtgat tccttctatc gaatgtggga
    12001 tctatattta caagcttgtg cagcttcatt tgaatcaagt aatatcgatg tgattcaata
    12061 tttgcttgtt caacctggaa acaatgacat cccaatgcat cgtgcataat tgaggcaaaa
    12121 gtactgttta aagactattt aaaaagaagc taagttttat gatgctccag aagtgaactt
    12181 ttttgtctaa cttctaggat tgtctctaaa gcttagtttc tttttcttta tattttcata
    12241 ataaaagttt ggttctttaa tttttaaaca tgacagaaaa ttttttcttc gttatacttg
    12301 taatagaata ctattttata acaaagggga tcgaatcaat gaaaaaaact gttatttata
    12361 ctagtttatt tgcagctttg tttttagctg cttgtcaatc aaataccaat caaggcacat
    12421 ctgggaatac gtcttccagt agcgaacagc gctcttcaca ggtatcggac tcctcaacaa
    12481 aagcaagcac atcttcgtct agccagacaa aaagttctag tgaagcaagt actcagtcag
    12541 atatcaaagt gtctgcagct cgtgcgatcg aattgttcca agataaatac ccagatactg
    12601 caattactag tttggaatta gatagtgatt ggggatctta cttctacaag atagaaggtg
    12661 tcgatgatca aaaagaatac gaagcaagaa ttgatgctca aaatgaaaaa atggagacag
    12721 agaatccaga aactctagat cgagatgaac aaaatggtca aaagaaaaaa gaagatggtc
    12781 tggatgttga taaattgatc acgattgagg aagcagcaaa aatcgccgtc gacaaagtag
    12841 gaagcggtac ggcaacagat tgggatttgg ataaagattt aggtactact tattgggaag
    12901 tcaaagtaaa agacggcaat caaagtacat cagtcaagat caatagccaa acaggcgaag
    12961 tactgtcaac tgaacaagat gattaagaat ttcttcggaa aacaagagtt gatttttctt
    13021 ttagtcatga tacactagac aaaataactt gtttgaagga gcgatttact tgagtttaga
    13081 aacgaccttt gccaatcata tctttgccaa tcctttgatg aatgcatctg gtgtccactg
    13141 catgactacc caggaattag atgaactggc tcattcagaa gcaggagcat ttatcactaa
    13201 gagctgtacg atcaatgaac gaaaaggaaa tcccgaacca cgctattttg atgttccttt
    13261 agggagtatc aattctatgg gacttccaaa cttaggtttt tcttattatc tagagtatgc
    13321 tcttgcgtat gaaaaagtgc aggaaaacca aaatcaaccg ttattttttt ccattgccgg
    13381 gatgagtgtc caggaaaact tggaaatgct tgagaaaata gaaaaaagtg ggtttaatgg
    13441 gatcactgaa ttaaatttat cttgtcccaa tgtgcctgga aaaccacaac tagcttacga
    13501 ttttgaggcc acttatgaaa cactgaaaga agtattcagc atcttttcta agccgctagg
    13561 aatcaaattg cctccttatt ttgattttgc tcattttgat cagatggctg atatcttgaa
    13621 tcagtttcca ttgacctatg tcaatgctat caacagtgtg ggcaatggtt tgtatatcga
    13681 tacagaacaa gaagcagtag tcatcaaacc aaaagaaggg ttcggcggca ttggcggaga
    13741 gtatatcaag ccgactgctt tggcgaatgt tcgcgctttt tatacacgtt tgaaaccaga
    13801 aatccaaatc attggtacag gtgggattcg gacaggacaa gatgcatttg aacatctgct
    13861 atgtggcgca agcatgttac agattggtac cgagcttcat aaagaagggc cggaaatttt
    13921 ttctagaatc ataaaagaat taacgcagat tatgtcagaa aaaggatata cgtcaattga
    13981 cgaatttaaa ggcaaattac gcaccatttc atagcaaaga gacgaaggtc atgattgatc
    14041 ttcgtctttt tttataaaaa acactcgtct gttcattcct gtgcaagcgt actcattgta
    14101 tgttagacga acttgtggga aaataacaga ggcaaaaagg aggataatat gaatgatgca
    14161 acagaattag caaaagagct taaagaaaaa gaatttagtt ttcaagaact agttacggat
    14221 atacagaaaa aaataaagaa gcaaaatcat gaattgaatg cgtttgtcgc gcttgaacca
    14281 ttcgagagta attcccacga gctattgatt ccccagtcag aaaaagggcc attggctggt
    14341 atcccatttc ctttaaaaat gctcggtcaa gaaaaaaagg gatggctagc tacttcagga
    14401 tctcgtttat ttgaaacaca ccgagcttct catacatcta attatgtgcg gcaagcagaa
    14461 gcgataggtc tagttccttt tggacaaacc aatgcgccag agtttggttt caaaaatatt
    14521 acagacccag tcatctatgg cccagcaaga aacccttgga accttgaatg tacaccgggc
    14581 ggatcaagtg gaggagctgc tgctgcagtt tcatcaggaa tcgttccttt agctggtgct
    14641 agtgatggcg gtggttctat tagaataccc gcttcgtttt gcggattgat tgggctgaaa
    14701 ccttcgcgag ggacgatgcc agttggtcca tatgcttgga gaggatggca aggagctgct
    14761 attgatttcg gcttgacagt ttctatgaga gacacggagg ctttatttta tgggatgaga
    14821 agtatccatt ccggtgcgcc atatcaagta tcgccagttg agtggcaaac acatccaaga
    14881 aaaaaacggt tgaagatagc tttttgtgtt gattcaccga tccactcaca gattagtgaa
    14941 gaggcagtac ttgctgtaaa aaaagctgta gatttccttg gaaaagaagg gcatgatttg
    15001 acagagattc cttacccact agatggtcgt aaactgatca cgtcttatta tcagatgaat
    15061 ggcgcagaaa cagcagcaat gatccgctcg attgaaacag gcatccagcg agctgtcaga
    15121 aaagaagaac ttgaacccat ttcttggact ttgttccaat atggtcagaa gctctctgcc
    15181 gctacttaca tcgattctct gcatgtatgg gatgaagcag caattgtcat ggaaaaccta
    15241 catcaagaat acgatctatt cctttcacca acgactgcat ttaccgcccc taaaatcagc
    15301 gaagatttgc aaagtgatgc gataagagca cagatggaac acatcagtga ttgttctgaa
    15361 gtagaaggtt tagacgttgt ttcttccatg tttgaggaga gcttgaagat cacaccttat
    15421 acacagttgg ctaatctgac tggacaacca gcaatcagct tgcctactca tttgacaaaa
    15481 gaaaacatgc ctctaggaat ccaatttatg gctgccagag gaagagaaga tttgctattt
    15541 caaatcggct atctatttga agcaaatcat cagttccatt taccaaatcc atggaaatag
    15601 cagaaacaag gagaagaaga atgaagaaaa aaagattgtt tgctctaata actagtgcct
    15661 tttttatttt aagcgcttgc ggtacagctg ccgctaatca ggaagataac agctggagta
    15721 atgtagaaaa aaagaaagaa ttagtagtag cgacttctgg cacactgttt cccgcatctt
    15781 attataatga tcaaaatgaa ttagttggtt atgatgtaga tttggcaaaa gaggtggcta
    15841 aacggttaaa tgtcaaaatc tcctttaaag aatacaacgt ggatggacaa atcacttctg
    15901 tttcaaaaag agaatcagat tttgctgcga acgattttgg tatcacaaaa gaaagagaaa
    15961 aaaaattctc cctttcagag actttcaaat attcatttga cagtatgatc gtacgaaaaa
    16021 aagatgattc aggaatccac tcacttgaag atcttaaagg gaaaaaagca gctggcgaac
    16081 ccaatactag ctatatgcgt ttagcggaaa aacacggagc taaattagtc acatatgaca
    16141 atgccacgaa tgatcagtat ttaagcgatg tagcaaatgg tcgaacagat gttattctaa
    16201 atgattatta tctgcagaaa atggccgtat ctgctttacc agatatccct gtaaaaatac
    16261 tggagaacgt ttatttcaat gaaaacgaaa gtggtttttt attgaaagaa ggaaatgatg
    16321 ctctgaaaaa gaaaatcgat ggcgtattaa aagagatgaa agaagatggg acgacaaaga
    16381 aaatatctga aaaatatttt caaactgatg tttcagtcaa accgaaagaa acgatggctg
    16441 agtcggtgag tgagtgatgt actttcctct aattgatttt tccctcatgt ggacttcact
    16501 tcctttcgta ctgcaaggct tggtatacac attagggatt ggcttcgtgt cgtttctttt
    16561 aggaaatctg gtagggttgc ttttgacagt tttaggtctt ttggattggc tgcctctgaa
    16621 tgtatttatt cgtttttatt tatcgttctt tagaggcatt cccgcactag tcctgctgtt
    16681 tctgttatat tttgggttac cttatcaatt aagtgcctta acggcttcag tcatctgctt
    16741 tacgattacc agcagtgcat ttattggtga aatctatcga ggatcactag caggcgtttc
    16801 ttcaggtcag tgggacgctg gtttagcttc tggtttttct ttctttgggg tattgaaata
    16861 tatcgttttg ccgcaagctt ttcgaatctc agtaccggca ctcagtaacg tagctatgga
    16921 tctagtgaaa ggtacttcgt tagcagcaac aatcacagtg ccagaaatat ttcaaaaagc
    16981 aaagatcata ggcggtcgga cattcgatta tttttctctc tatattttag ttgcactgat
    17041 ttattgggtc atttgtatcg ggatcgaaaa agtgcaacag tatttagaaa aacgttctat
    17101 gcatcagtca atctgaaaaa tagaaatggt gctagcgtgg ctggcaccat ttctattttt
    17161 tgtttcttgt atattctgcc tagtatttta aaaccatttc atgtaaaatg taaatcgaaa
    17221 atatgttcgg aggtagaaaa catgaagacc ccgctaacca tcgaaataga atcctcgtta
    17281 taccaatatt gcatcgagca aggcggcttg gttgtagaag aagtcacgat gcctgatgac
    17341 caaggaattg tagatacgct tagctgcttg acaaaatttg atggaagccg agaatggcga
    17401 tgctatgagc tgaaagtgac aaaagcagat tttcgctcta cagccaaact gtcatttgtt
    17461 ggacattata attattttgt tttaccaagt aaactatatg aagaagtaaa aactgaaatc
    17521 cctacaggaa taggtgtttt agtgtatcgt ccgtacacgg ttgaagagga gatgcctgcc
    17581 tctggtacat ttctgattgc gaaaaaagca gcaaagaaag agcttgctgt accggaagaa
    17641 gctttgacaa accgcttcat ggcttcttta ttcagggaag taagaaaagc aaagcaaatg
    17701 gagcgaggcg taaaatattt tccaacagat caattgtaca aagaattgaa aagacgttca
    17761 gaaaatcaag atccattttc taacgaacga tattatgaac ggtttttaga ggaaatagct
    17821 agtcaggcaa tcaatgagtt gcaagaagaa gttatcgcgc ttcagcatga ttatgaatat
    17881 ttgaggcaac aacagcagat ccgtcggttg cctacagagc cattggagtg aaaaatatgt
    17941 actatcctta tttaagagga aaacaatttg acctattagc attaaaagaa gcactgtcgc
    18001 gaggattgct ctccaataaa atccaaccag tgatcgaacc agtacgtgat tccgctacgc
    18061 ttaaaaatgt gatcgaatta tttcaaaaaa agcaccatcc aatcgctgtg atccaaaatc
    18121 cccaagtagg acaattcaaa ttattcgatc agcatgtgca cagttggaca gtcaaagaaa
    18181 atagctctgt cgtccctgca cagatcttaa cgccagaaaa tctcagtgaa gtactggatt
    18241 cacctccagc gtttcttgtt ttcgatggac agcactaccc aaaagataca gaggtgtgga
    18301 aacagttggc aggagttgat tcgaaatttt tgataccaga tactagtcgc tttcgcatct
    18361 ggctgcccga aaacaaaatt gtgatccgtg actcttttca aacgagaaag catgttgaaa
    18421 gttatgcaga taaaacagat gactttttta gtgatgacta tctttttttc cacgcagacg
    18481 gatatattgg attttctgat ttcacgatcg aaggtagccg ttatttcgat aaagggttcc
    18541 ctagccgagc gcttgctatc catctaacgt atattgatgc ttacggcaat atacgcgtga
    18601 aacattttgt ctctgacagt aacgactctg ctaaagacca agcattgaag tttcttgaag
    18661 caggagataa aatgaaaaaa tggatcatgc gtcaccatca tcaactcttg attacttcag
    18721 gaatgattga attattggct ctttaccagc aacaaaaatt ccctggactg ggagtgttga
    18781 aaaagtggtc acttatgcat catttggaac ttattagtca cctgctagat catccaaaag
    18841 attggcttaa atattattca aaagttcagg aactatatga agtgatccaa tgattagata
    18901 atgtaaatga aaaaggaata gaaaagagga aactggatgt atattcggca aacaaggaaa
    18961 gaagaagtag aagaagtggt agaaatcatt aatgccgcag cggatttcat tgcttcgcaa
    19021 ggctctcctc aatggcaaaa cgggcagaaa ccaacaaaag aaacgatttt gaacgatatt
    19081 gaaagaaaag aaagctatgt attaatagtg gaagatcaaa ttgctggaac agctgcatta
    19141 gtctcaagcg tggatcccgt ttacacaaaa atagatggta gttggaaaga atcaactggt
    19201 ccttatttat cgattcatcg tgtcgcttta gcagaaagta ctcgaggaaa aaaactagca
    19261 aaaccgttct tagaacattt gttgacgatt gcagccagca aaaatatcca agatatccgt
    19321 atcgatactt atccagctaa tgaaccgatg gaaaagacca tctattctgc tggattcact
    19381 tatcaaggga tgattgaatt tccttttgaa cacggcgaaa gaaaagcata tcaaataatc
    19441 atcaattgac tataaaatca tctgagcaaa gataaagaca ttaacactac tgaaaaaaac
    19501 aatcatatga tagccaagag gttgtaacag aagtggccag cttcaaaaaa caagaaagaa
    19561 tttccgaaaa tgcttctcaa atttttgtgg aattttagcg tattttacga aatagctgct
    19621 ttctgaaact cccttcatcg agaggtcgtg acatagcttt tgtcacgacc tctcggctta
    19681 tcctacgagt attattcgat acatttatat caataatcct ttttttattt tatctgcagc
    19741 ttcttggaac gctccatcgt ttgacacgac taaaagtgag gggatagctt tcaaacgttt
    19801 caactgtgct aaatcttcta cataaaccgc cagtctggct gaaatctgtt cagatgaatc
    19861 tccacgtttt ttcaggcgcg attgcaatgt ttctttagag atcgtaataa agataggacg
    19921 gactaccgtc ccgaaatact catataaatg ccaaaaacca tttgctgtca aaacggcgta
    19981 acaatttcct actgtcagtt tctttttaat ttctgcttta ctggaaccat atttatgttg
    20041 agcatattgg tcccactctg caaactcatt tcccttgatc atctgattga atgtattgtc
    20101 agaaacaaaa taataatcct cttgatcttt ttccccaggt cttggtgatc gattcgtgta
    20161 agtaatgatc ttttgttccg gctgaaaaat agcttctgcg agtgaagttt ttccagaacc
    20221 agaaggaccg ataaatacat agcaataatt cattgtcatt tctcctttga tgattgaaca
    20281 agtgaaaaag ctttggaaaa tatttccaaa gcttttaaaa gtaactttgc ttttttgtat
    20341 attataccag caagccagtc acaatagcac ttaaaaagct gactaaagtc gctgttagca
    20401 aaattttcaa tccgtgtttt gcgacaagat ttcctttttc ttcatttaat cccttcatcg
    20461 caccagaaat gatcccgata gaagagaagt tggcaaatga aacgaggaag acagatataa
    20521 ttgctgttgt acgctcagta aaatggaaat taccatttgc taattctgtc atagcaacaa
    20581 attcatttgt aaccagttta gtcgccatga tactaccggc atccactgct tctttccatg
    20641 ggattccgct gatgaaggca agaggggcaa agatgtaacc taggatctct tggaaagtga
    20701 tgccgaatat cccgtggaag atagcattga tcatggcaat caaagcaaca aaaccgataa
    20761 gcatagcagc aaccgtgatc gccacatgga aaccatcaag aatgtattct cccaacattt
    20821 ggaaaaatgt ctgttctttg ttttcttcaa tgatcagctc atcttctttt tcttctaata
    20881 catagggatt tacaattgaa gccagaatat aaccgccaaa taagttcaaa acaagggcag
    20941 tgatcacata tttagaatcg atcagtgcca tataagatcc gacgatcgac atagaaactg
    21001 tagacatagc cgatacactc atggtgaaca aacgtttctc agataggaag ggtaattcct
    21061 tttttatgga aataaaaact tccgattgtc ctaaaatagc agaagctact ccattataag
    21121 attccaattt gcccaacccg ttgattttac ttaatcctag accaacagct ttcataaata
    21181 atggaagaat cttgatatag cgtagaatac cgataatagc agaaataaat acaattggca
    21241 tcaatacgga aagaaagaaa ggtgcacttc ctttatttgc tacaccggca aaaacaaagt
    21301 caacaccttg cccagcaaaa gcaagaagat gatcaaacat ttttgccaat acagaaacaa
    21361 ccgctgtacc aaaagttgta cgtaataata cgaaaccaag aacaagctgt aaaacgaaca
    21421 tcacaattag tggtttcaat ttgattgctt ttttgttact gctgatcaaa aaagcaagcc
    21481 ctaatgtgac aaataaacca ataataccta ataaataact caaataatca ctcctattcc
    21541 aaattccgtt ttattttacc tgttttgcaa ataaaatact aatctttagt gaaattttca
    21601 ttactttttt agagtgaaac gcattcattt tccattagaa aataaagcga acaaaataaa
    21661 aggtttaaaa agtgtaacgt cttagtaaag tctataaaaa aacgaaacta tcgattaagc
    21721 taatagtttc gttttcaaca tttataagta aactttttct attggtaata tagattttcg
    21781 gaagggtaga caggtgcgca ggtaatatcg attcctagtt ttttcaatgt ttgttcatca
    21841 tttttattga ccatcacagt agagtgggct tgtgctccct caagttcagc tagtttatca
    21901 taagcaactt gagcgattgg attcgttact gcactgattg ataaagcgat caagacttca
    21961 ttgatgctta gtgcatccaa agaggaatga agtgtctttg atttcaatcc ttgtattgtt
    22021 tcaagaacta atggtgacaa taaaggaatg tcatctgcga tatgggctaa atgttttact
    22081 gcatttaaga taactgccgc tgacgcatcc atcaatgaac ttgtacgccc ggtaatgatg
    22141 acttcatctg gtaattcgat tgcaatcaca gcagaaggat cttttgtagg actttgcgct
    22201 tgaatcttat ctgcatagtc atgggcaggg actaccacgt ttcggtcttc aggacgtaaa
    22261 ccgacttctt ccataatcag tttgattcga ttaactgctt cttcgtcgat caatcctttt
    22321 ttgaagtcgc attctgtttg gaaataacga cggatgattt cttgtttaga ggcttcttgg
    22381 acaacggtat catccacgat cccaaatcct acacgattca cacccatgtc agtaggagat
    22441 tgataaacag attctttacc agtaattttt tcaataatac gtttgattac aggaaatgtc
    22501 tcaacatccc gattatagtt cacagctact ttattgtagg catcaaagtg gaaggaatcg
    22561 atcatattga catcttttag atcgactgtg gctgcttcat aagcaatgtt cagcggatgt
    22621 ttcaacggaa cattccatac tgggaaagtt tcgaacttgg agtaaccagc tgcatgtcct
    22681 ttttggcttt catgatacag ttggttcaag gaagtagcga gctttccact tcctgggcca
    22741 ggagctgtca ctacaacgat tggtttagtt gtttcaatat actcattttt tccaaaacca
    22801 tcttctgaga cgattttttc tacgttgact ggatagtctt cgatttctga gtgtttatag
    22861 accttgatgt ttcgtctttc tagtttattg ataaagactt tcgtggcagg ctgtccacta
    22921 tagcgagtga taacgacact gttgattaat aagccataac cacgtaattc atcgattaac
    22981 cgcaagatat ccatatcata agtaatccca taatcaccac ggatcttatt acgttcaata
    23041 tctccagcat agacgcaaat cagtatttca gcttgatctt tcaatttttg cagcaatttg
    23101 attttcgcat cttcttcaaa tcctggaagt acacgtttcg catgcttgtc gtcaactagc
    23161 ttcccaccaa attctaaata taatttgtca tagtggttca ctcgttccaa aatatacgct
    23221 gactgctctt caatatattt ttctgaatca aaaccaattt ttttcactag gttccctcct
    23281 taagtactaa agcatttttt catttttttg aggattcgtc aactggaaga gcgaaattcc
    23341 tcaaaaaaac aaagaaaatg gtttaaacca acttgtctag atagttattc attggtatga
    23401 tagtttttga taaggaaggt gctacatgaa aaaaagacag aaaaagaaaa acgcatataa
    23461 acactatatc cgttcgattt ttaccggtta tgaaagaatg cttgaagatc ccgaattgga
    23521 acaattgacg tttacttatc taaacgaaga aacgcagcta actcgtgatg agcatcagcg
    23581 cattcatttc acaacaagag atctgcctag taaataaaaa ataagataaa ggtcatcgga
    23641 ttcgattctg tcctatcaga tggaaagact agttgatcga aaaaaaggct gtaccaaatt
    23701 ttggtgcagc ctgttttatg gagcattgcc cgctcttttt tataacaatt ttttacagaa
    23761 aatggtacta ttgaagtatt aataagtgaa aaacagatga gtaagaggag gcaagtagta
    23821 tgaaagagcc agatacaaat gcaaattatg agccagacga actagaggag acgaatgcgg
    23881 atcaggatac aggacaagaa tcgtcttctt tttacgatat caaagaaaaa gcaagcatga
    23941 atctttccca attattagaa gacttacagg cttttgaaaa agctgtccgc gaagaagata
    24001 tccctgagat ctaccgttta tacaatggcc gattgaatga agaattaaaa agaagctcaa
    24061 atgaaaatca cgagatcgat caattgctga tgcgtaagat ccatgatcgt tttttacagg
    24121 aatttccttt tatggaacaa gtagaaaaca tctcgccaac gatgagctat tacaaaatcg
    24181 gcacttatta ccatgatcgg cccacggtcg gtattgatgc aagtctgcca gaaatttttg
    24241 ttttgcctaa gatcgatgaa gagtgggaga aatattccca accggagtca acggactatg
    24301 acaaaaaaat caatgagcta gacgcaaagg tgatcactgc tcagacagaa attgaacgtt
    24361 tagatgaaca aataaaagaa atcaatcgac aaatgactga tttgaacgac aataaaggat
    24421 tcttgaatcg taaaaaaatc gaggaagaaa ttcaagaatt agagaagaag aagcaagtac
    24481 tatctaatga aaaattaggc tggcttcctt atattgagac gcctgaaaca atccagcagc
    24541 aaaaagaagc attgaagcaa gaagcaagag cagaccagct tcgtgcagcc atcgtagaaa
    24601 aagaacaaag gcaaatcaga cgctatttcg gtagcaaaga gggattcggt caagcaatcc
    24661 atgaattctt gatgaattat cttggcaatg agaatcctaa taatcaatct aatgaaggag
    24721 gttccgagta tgaatgaaca cgatgaagca gaatggacaa aaaatgaaga acaaacagaa
    24781 gatcatgaag aaacgaacac ttcattggaa gaacaaacaa gtaatcctct ggatgacaca
    24841 gaagaaatcc ctatgctaga ggaaacaaaa atacacgaaa aagaaaaagt aactccgacg
    24901 aatacgaata ctgcagaaaa cacccatgct tacgaaataa ctgaaaatcc cgggtattta
    24961 gaaggaaaag agcaagatca tcaagatatc gtcagtttga ttgaaacagc ggaagcagaa
    25021 ttagcggatt tacgtatgag aaaagatttg atcgaatcag attttccaca attattagaa
    25081 tcatatgatc gttttatatt gaatgaagaa ccaatctcca cgatcggaaa gacaagcctg
    25141 atcgaatact tcacgtatga attactgaaa ccgttgaatg atattggtct ggaacggtca
    25201 aattcagctt atgacacatg gaaaacaaga catttttcga tcaattatac gttgaatgga
    25261 caaaacgaat tagtcttttc ctttgtatta ccgaccatcg atcaacgata ccaagtggaa
    25321 tcgatgagtc tcctaaacgt atcaccagag acaatggaaa tcaatgtcca agatgaccgg
    25381 gtgctttctt tgatccgaca ctggtcagtg gatcgagtat tctctgcagg gcagatcacg
    25441 atattcaatc acaaattgaa tcaattatta gcccatgcaa gaacacttgg ttttaccgtt
    25501 aatcagacat tactagacaa tacgaagcca cttcgtttga atcttcagag cgaatttgaa
    25561 ttgacgaatg aagtattgga tgatattttt atcgtggcaa tgaaaaatcc atcctacgat
    25621 atggaaaaga tcaacgaaac tacttatcaa gtacgattag ataaaggaca gtctttaacg
    25681 ataacaacaa acgaaaaaga tcaaacagtc ttgtcgatct catctggaga ctacccacga
    25741 tctgtcattg atttctttat caattacgaa ttcttggtcc cattaatggt gagaaagtcc
    25801 tgattggata agttggatta ccagatgtca ttcagataat tctgttccaa aggacttgcg
    25861 gcagttatcc agaataattg tcacaagtct tttctgtatg tactaaatgg acgtgaataa
    25921 cttgctgatg aaggagggat ttcattagga atgtccacaa ataaaatagc acagcttagc
    25981 ttattgtctg ctgcttgtgt agcaggtagg atcgcttttc aatttattcc gaatttccag
    26041 ccaatgactg ctattttttt atttatagta ctttacttaa gcttaaaaga tgcgttaatt
    26101 gtcatgagtc tttctattgc gatcagcagt ttttattttg gtgttggacc atgggtcatc
    26161 ggccaatgga tcagctatac tgttgttctg agtttgtttt caatcgtctg cttgagaaaa
    26221 acagtgcaaa ggaatctatg gttaaaggga gtctgttttt ttctggcggg catggtttac
    26281 ggaataggta tgaccgtttt tgatacgctg ttatatcgtt tgcctcaacc ttggatctat
    26341 taccttcaag gggtgtcgtt tgatttgatg cacagtatag gcaatgttgt gttctttctt
    26401 gtttttctgc cagtcgtcaa acgtttttac aatcattcag gaggaaaaaa tgaaaaaaat
    26461 aatttatagt ttgcttgcaa tgagtgtcag tatactcatt ttgacaagtt gcagtacaac
    26521 ctatacacaa tcggcttcca accaaaagga ggaagtaaaa acatcgcaaa aagcaacaat
    26581 cacgttacaa gaaaatggtc aaaacttttc ggaaaaagaa gtgttcttca aaaaaggcga
    26641 tgatttactg agtattttga aacgaaattt tgaagtcaaa gaagataacg gcttcatcac
    26701 ttcgcttgaa gggcactcac aggatgagaa aaatcaactc tattggatgt ttactgtgga
    26761 cgggaaaagt gctactactg gtgccaaaga gatcaaattg aatgatggac aatcggtcat
    26821 tttcaatttg tctaaactat aagtttcata aaaaactgtt aaagggcgaa tattgccata
    26881 attcagtgag ttcagttgat gaaagaagga aaataacatg gaaaatttta aaaaaagcgg
    26941 aatgttttcc gtaattgctg ctctaggggc taatattcta gttgctatca gcaaatttgt
    27001 cggctatgca atcagtggca gtgccgccat gctaaacgaa agcatccaca gtatcgttga
    27061 ttgcagcaat cagattttgc tgttattcgg tgataaacaa gccaataaag gacagagcga
    27121 gttgcatcaa tttggtgaag gacgagcaaa atactttttc agtacaatcg tcgcaatgat
    27181 gcttttcttc ggcggtgggg cacttggggt gatggaagct tttgaaaagt tgacgcatcc
    27241 atcccatgaa gtgggtaatc cgatcattgt tatagcaata ctgttatttg gtttggtaat
    27301 cgaaggaagt tcgttacgcg tggcaatgaa agaaatcaaa gaattgaata ctgaaaaact
    27361 ttccacgatg cgctttttgc gcgaaagtcg acacagtgaa atactgatta tttttacgga
    27421 agacttgtgt gctgtaatcg gtttggtctt ggctttagca ggaacaatat tgacttatgc
    27481 aaccgggatt gctgcatttg atgcgatcag cggattgctg atcggtttct tgctgatggg
    27541 agccgccatt ttcctagcaa aagaatttta tagtctgatc atcggtgaaa gcgtgacagc
    27601 aagcgattta tcaaaaatca agttagcttt tgaacgtcct gagatcagtc ggctgatcga
    27661 tataaaaaca gttcatttaa gtccaacgga gattttagtt gcagcaaaag cagatatcgt
    27721 tggtaacaaa gagaatgaag cttactcggt catcaatgat attgaaaaaa atatgcgtca
    27781 gtctcttcct gacaagaaga tgtatatata cattgaaaca gataaatatg acccaaatta
    27841 ttctcgtaaa taaaacgttt attcatgaat tgaagcaaaa atgagaaaaa tataatcttg
    27901 tttttaaata aaacggctac aatttagcga atttatgtta caatgagtcc gctgtttatt
    27961 tgttgtaatt aaaggagata ttttaatgaa caaaaagaaa agtgcgccat ggcttcaagc
    28021 tttgcatgca gtgatgccac tttgtataag ctatatacca gtaggattag cttgcggagt
    28081 attgttgcaa aaagttggat ttgatcctct cttatcagga ctgttatcga ttctggtctt
    28141 ttccggtggc gcgcagtttt tagttgcatc tatgcttacg acgcaagcat catttgcaac
    28201 gacattattg atggttttct ttttagaatt acgctataca ttattaggag caagtcttgc
    28261 cggttttatg aaaaaagaaa agcggacgtt tttggctgtc ttttctcaat cactgaatga
    28321 tgaaaactat gcggtgaact acttaaagtt ttcaactgac ccttcctgga ataaaagaaa
    28381 ggctttatat gtcaattggt tctcaatgac tgcatgggcc ggtagcaata tgatcggtaa
    28441 ttttttcggc tcggtgattc gagtagatgc tgaccttgtc cattttgctt tgacggccat
    28501 gttcattttc atgtttatca tgcagatgaa aagcgcacta ctgatcttta caggtttatt
    28561 ctcaggcgta ttaggggtcg tattcatggt attattccaa aatactttcg gattgattgc
    28621 agcaacagtc attgcttcat ttgccggatt tatgctggag aaggcattca aaaaagaaaa
    28681 agctaagaaa ctaagagacc gcggtaaaga tgtcaatgag ccgctcttca acttcccgga
    28741 acaggaggcc aatcaccatg actaaactat atttgctact tttagttgct tgtctgttca
    28801 tcgtggcata tatcccgcgc ttgttcccga tgctttattt tactcatcga aaagtgccat
    28861 cctggttcag tgactggatg aaatatgtac cggtggcatt atttgcggcg ttagctttta
    28921 aagatgtttt cattactcat gaacatctgg atattgcttg gaatatcaaa atagctgcaa
    28981 tgattctagt agcaggcgtg gcttacaaaa cacgttcgat ggcgttgtca gttttgacag
    29041 gacttgcgtc tgtctttttg ctgtctatgc tttaaactgt tttattttat taaaaacaga
    29101 gattgcgaca taagttgttc aaactgatct atccgaactg catttgcaac agtcaattct
    29161 ggatgcaagt ttattcgtag ggataaaaaa gattagtgtt ggcttatgat gcaagctctt
    29221 ttttatttta ggaattagag agggatttgt ccttctatga ttttttgcta taatagggaa
    29281 gatgtttatt ttatgaaaga atagttgagg gaatttaaat gaataaaaaa ttgatgcaag
    29341 gaacattttg gctaaccttt gctaatcttc tatgtaaagt tttaggggta gtctatttga
    29401 ttccctggct aagtatgatg gggaacaatc aagatggtat gcttgctacg acattgtata
    29461 atgttggcta tcttccttat ggattgttcc tgatgcttgg tacagtcgga tttccaaatg
    29521 cgattgcaaa aaaagtagct gtagccacaa aagaaggaga taacgctgct tgtcggctga
    29581 tttttagaag tacgatcaat atcatgtttg tcatcggtat cgcctctgct gcactgatgt
    29641 atttatttgc tcctttacta gccggaatca gtccgattgc taacgttaat aatgggatac
    29701 tagctatcag aagtttatgc ccatctttga ttgctatccc aattcttagt gcaatgagag
    29761 gatatttcca aggaaaaaat gatctgcggc cttatggaac ttctttgatt atcgaacagg
    29821 ctgtgcgagt gatcgttatc ttggctggta cttattactt gcgcgtattg actgacggaa
    29881 ccatattaga agctgtattg atcagtacag tcgcttcttt cttcggtggg ttagctgcga
    29941 ttatccatat gtatatcgtc ggacgcagaa aagacttctt cgaacttaaa gattttttga
    30001 tttccagccg ttatttcgaa agagaaaacc gatctgcctc tgtctctatc attcgggaaa
    30061 cactaccgtt tatttttgtc ggctcagtca ttactatcgt tcaaatgatc gaccaagtaa
    30121 cgatgaaacc actgcttcac tttttccgtc cagagatcgc agatcagcaa ctggaattct
    30181 tattcagccg tgcttctgtc aatccaaata aattgacatt gatcctgatc tccatggtag
    30241 gaacagtagc tataagcagc ttgccaatat taagcacgat gaagaaaaaa gatcggatac
    30301 aaatcgaaaa aacagtagga gatagttttt cgattgcgtt attgattctt cttccttcat
    30361 tgactggaat gtctttatta gctggaccac tatacacatt gttttttggc tatgatcctg
    30421 aaagtgtcgg atatttccaa atggctttgc tagcttcttt gtttttctct ttattcacga
    30481 tcctatctac gatgcttcaa tctttgaatc accatcgttt tgcgatccga ttaactgtag
    30541 aagcaattat cctgaaagtc atcttccaag taatcggatt aggattagtt ggcggatacg
    30601 ggatgagctt atcaaatggc ttagcattcg gtattgtctt tgttcgcggc tatcacttta
    30661 tgtgcaaaga ataccgaata gcacctttag caaagatcag caattttttc ttaaaaactt
    30721 tccgctccac cctgattatg cttgcagtat gttttgccgt tttctttttg ctgaatcagc
    30781 gattgtcaat ggaatcaaaa agctatgcaa tgatttattg tgtggctgta ggaagtattg
    30841 gcggcttagt atttttattt tctcaattcg gaaaaaatgg gtttcgaatg ttgaaaaatg
    30901 ttaaacatca tagcagaagc aaagaatagg ttaactaatc gttttttgct gtcacttgaa
    30961 aaacggcaac tcgtatgatt acgcttgtcg tttttctatt ttccaatttt agtttcatat
    31021 ctaatcttac ttatgatata gttataaggt ctggaaaaat tctttgaaac gaggaaatta
    31081 aacacatgaa acttgcagta gttacagata gttcggcata tctgccggaa cgtatcaaga
    31141 accatcccga cttattcgtt attccaatcc ctttgattat ggatgggaaa atttataacg
    31201 aaggaatcga tatcgaagcg gatgaatatt atggactttt aaaaaacagt aaagattttc
    31261 ctactacttc acaacctgtc gtaggggaag ttttgggttt atatgaggaa ttgaaagaga
    31321 aagggtatga cacgatttta agtatccatc tttcttcagg gatttctggc tttgtcaaca
    31381 cattatttgc gatgaaagat gacatcagcg gagtaacggt cattccttat gactctaaga
    31441 tcactagtat gccgatggga cacatggtag aagctgcctt agacttaaat gatgaaggtc
    31501 agtcccttga tgaaatactt gcacatatcg atcgaatccg agataatacc tacgcttatc
    31561 tgattgtaga tgatttgaac aatttagtac gaggaggacg tttgacaaat ggtgcagcgc
    31621 tgattggcag cttattaaaa atcaaaccga tcctgacatt ttctgaaggg aaaattgttt
    31681 tattcgaaaa aatccgttca agtaaaaaag catttgctcg agctgaagaa attattggta
    31741 gaagaaataa cgaaatacaa ccgccagtca aactttacgt gatacatgca aataatttag
    31801 aagtagcgat tgcggagaaa gagaaattgc agaaaaaata tccaaatgca gaaatcgaaa
    31861 ttggtcattt cggaccagtc attggtacac atttaggtga aaaagccatc ggcattgcca
    31921 tttcagcgca ataattcctt ttattcaaaa aacataccaa aaatattcca acatcatctt
    31981 ggactttcta catgttacta atgagcgtgt aaaagaacga gatggtgttt ttatttctat
    32041 caatgaagct ctttttcttt gcaatcctca cttcaatcct ctataatgtc gcatatagtt
    32101 tagtaaatga gtaaactact aatttactta tttactaaaa ataaaaggat gaggagttaa
    32161 aataatggaa ataccaacaa atttaaaaca taaaccagta atcgttgtag aagactatga
    32221 taaagttgat ggaagaaatg cattaaatac ggatgcaaaa gggctttcac tgggccttgc
    32281 tcagtggaat gatcgtggaa aagtcgatat ctcaggcaag gtatggcgac atactggaga
    32341 aaaatggtca cgacagtcgg aagaattacc aatcacacgt attttagatt tagcgatctt
    32401 agctgcacaa ggaagtttat acttccaaga tgcttatcgt tatgaaaaat tttatgatcc
    32461 agaaaatcca gtcgtagaca tcattggatt acaagggaac cgaatgacgg tagaagtaga
    32521 taccaaaaat ccaaagatcg atgaagacat cattttgtat tacgatacac tacaaaaaga
    32581 cggagaactg attggggaac gattccgtat tttaaaacgt cttttagatg agctaggata
    32641 ttaatagaca gagatgatca aaaggggaag agaagcatgg agaatttctc actaacagaa
    32701 aaccgaacct tttcacggct agaaaagcaa atgatctgga agaaaccgaa aagccatcgg
    32761 acaagtgcag aagaatggcg gatcgcctcc gaaatcaaag ggaattggca agatcctgaa
    32821 atgaaaatca gtaacgtact tttggaagga gatgccgggt cggggaagac acaattagcc
    32881 aaagcactat ctgctgatct gcaacttccc tatacaaaag tgacctgttt tgcagatatg
    32941 gacaaatcag atgttttcgg agccttatta cctgtagtag attctaataa ggaacaagac
    33001 caagaattac tagaagctat ttaccaaaca gatacacttg aagctgtact gacactgatc
    33061 cagaaccatt acggcattga tcctttttct gctaaagaaa aattagcaga gctagttcaa
    33121 aggatcgaag ctgattatcc agatgcaatc cattacagct attacccttc tgaaatcgtt
    33181 cgagcgattg aaaaaggata tttattagag attcaagagc cgactgtcat ccgagatgcc
    33241 tctgttcttg tggcacttaa ctcagcgctc gaaccaaatg ggatgttgaa tttaccgaca
    33301 ggaatcattc gtcgccatcc agattgcgtc attgtgatca ctacaaatcg aaattaccaa
    33361 ggaaatcgcc cattaaatga atctttaaga gatcggatgc aacatgcgga aaaaatggat
    33421 cttcctgcct tagaagtcat ggcagaacgt gcgatggcga aaactatgat ccaaaaacaa
    33481 gaacttctct taaagatggc agagattatc cgtttgttgg atgaaactgc aaaagctaac
    33541 gccatcaaag gtgtagcagg aatgcgttct tatttttatt gggcaaatac ctataagcaa
    33601 ggacaagatt tactccagtc gatttatcca aaagttttgt ataaattatc cactgattca
    33661 gatgaattgg caattcttga acaagctttg tctgacagtg gattgctact ggaacttcag
    33721 gacatattga gaaaagaaaa atggggtcat cctcaatctg agcatacaaa aggaagaacc
    33781 attagcgccg aagaagcaaa tgaacgaaac atcactgaaa atgctgaaga aattctgcgc
    33841 ttagatgaaa agaaatcgtt gtctgctgaa gaaccaaatg agggagaaga gaaacaagaa
    33901 gaaacaatag aaaaaaacga gattcctcct caaatgcaaa aagaacgcag tagcgatatc
    33961 gaaggaaaaa atcaaaaaga acaacaaaca ggagatgatt ctcaagaaat gtctgcttct
    34021 gacatggaag cacatgataa ggaaatcaag aagcaactga ataaagaagc gcgacaaatc
    34081 atgaaggaaa cgattcatga aaaagaaggt ctcatcgttc accgaccagc tttccaagga
    34141 aaaacgccgg aagcacgtga gctacacatg caagtaatgc caatagtaga atcacttagc
    34201 cggcaaattt tagagttact ggataatgaa caaacagaga cgtaccaaaa aggaaaatac
    34261 gaaggtcagc ggttcaatgc aagcaaagta gcatatggtg atttgagaaa ttttgacaaa
    34321 aagaacccgc cacatgagca accttcttta gcggtagctg tacggatcga tgaatctggg
    34381 tcaatgatac gggatgatcg gatcgaagcg gcaaaaaaag cagcgattgc cattgccgaa
    34441 ttttctaaga aagtcgatat cccattgttg atttacggag atacagcaga ccgttcgtca
    34501 agagaaaaga cttctttgtt ttcttataaa gaatttgaag acggatttca atggttaaat
    34561 gaaaaattag tcactatgaa accaaggcaa aacaatcgtg atggtgctgc acttcgttta
    34621 gcagcagaaa aattaaacag acaatccgca acaaccaaac tgttgcttaa tattagtgac
    34681 ggtcagccaa aagcgttgcc ggattataca ggcaaaaaag caaaagaaga tatccagtct
    34741 gttttgaaag aatatgaacg tcaaggaatc ctatttgtct ccgcagctat tggccaagac
    34801 aaagaagaaa tcaagtcgat ctacggtgaa agtcgttttg tagatattac tgacttgaat
    34861 gaatttccca agcaaatgat tcaactgatt gcccgctatc tatgataaaa taaagctcaa
    34921 cgaacgcact tagcagattc gttgagcttt tcgtttctag ttaccggtaa caaggatact
    34981 tctaaaatag aatcggttat aatcaagagg gaccgttaaa ggagtgaaac gatatgatac
    35041 aagaacaaaa atggtggaaa gaagcagtag gctatcaaat ctatcctgct agtttcaaag
    35101 atagcaatgg cgatggtcaa ggagacatca atgggatccg tgaaaaactt aattatttga
    35161 aagatcttgg tatcggcttt atctggatca atccgatcta tcaatctcca tttgtcgata
    35221 atggttatga cgtaagtgac tatcaagata tagaagagag attcggaacg atggaagatt
    35281 ttgatttatt gctaaaagaa gcacatgaat tagggatcaa agtgattatg gatcttgtca
    35341 tcaaccatag ttcggatcag catcaatggt ttgaagaatc gaaaaaatct aaagaaagcc
    35401 cgtatcgcga ttattacatt tgggtcgacg gggtagatgg caaagaaccg aataattgga
    35461 catcgatttt cggcggttct gcttgggagt attctcatga aactggacag tattatctgc
    35521 atgtttttgc aaaagaacaa ccagacttaa attgggaaag cgagaaattg aaagaagaac
    35581 tattcaatat gatccgatgg tggttggata aagggataga tggatttcgt ttagatgcga
    35641 tttctcatgt aaaaaaagat gaatattcag taaaagccac agagaaccct ttctcaccct
    35701 ttcaaaatgt ctcaggaatc gaagaacatt tgaccgattt gaaacatgtt tttgaagagt
    35761 acgatatcat gactgtcgga gaagcaagtg gtgtcactgc agaagaagga ccacaatggg
    35821 tagggaaaga cggttatttc gatatgatat tcgaatttga tcatatccat atctggcagc
    35881 aagaaaaaga agggcaatta gatgtcctta aattgaaact tgcattaagc gcttggcaaa
    35941 cttcattgga tggtatcgga tggaacgctt tatatatgga aaaccatgat gttcctcgtg
    36001 ccgtttcagt gtttggagat actcgtcccg atttttgggc tatgtctgca aaagcaatcg
    36061 ctatgatgta tttctttttg caaggtacgc catttattta tcaaggacag gaaatcggaa
    36121 tgacgaatat gccctttgaa tcgatcgatc aagttgatgc agtagattcg aaaagacttt
    36181 ataaaaggct gcttgcggaa ggtaagacaa gagaagaagc attggatatc attcgtgaaa
    36241 caacgagaga caacagcagg acacccatgc aatggacttc ggaacaatat gctggttttt
    36301 ctacacatga accttggctg atcactaatc caaataccaa aacgatcaat gtagaacaac
    36361 aagaatatga accagagtcg gtcctgcaat tctataagaa catgatccgc attagacaaa
    36421 ccaataaagg tctgatatac ggttcttata aagaatatct tcatgaacat ccacaacttt
    36481 atgtctatga aagatattta gaagatgaac aatatcttat tatggtaaac ttaacagaat
    36541 cacttgctga ctatgaactt ccaaaagaag cagatcagtc ctggacatta ctcttgtcaa
    36601 attcctctag cggagaattt gaagctaaag gcatactagc accttatgaa gctcggttat
    36661 ataaaacaaa caagtaaaac ttcctcgtta aagttcatta gttggacttt gcgaggaagt
    36721 ttttcagatt gctctgtcaa ttactcattt caataattcg ctctaggacc accgatatat
    36781 ttaggacgag agcgaagggc tgtcacgtga gcttgtccaa gggttttcaa acgaggtctg
    36841 acaggtactt ggacatgttt gatatgcata ccgattgatg tgtcaccgat atcgataccg
    36901 gcttgtccaa ctacgtgttc cacttcgaca ggatcattga actggtcaaa agcagcaaca
    36961 gaacaagcac ctccagcatg tagtgcagga acaacagaga caatttcgaa attttttgct
    37021 tctgccactg ttcgttctac tactaatgct cggttcaaat gttcacaacc ttggacagct
    37081 agcgcaattt ctttaggatc caacaactct tttaacgtac ggatgatcca ttgaccaact
    37141 tccgcactgg aattttttcc aatatgtcct ccaacgactt cgcttgtgct gcatcctaaa
    37201 acaaaaagat cacctttttt caagtgtgcc tcagccaata tgtcattaac tatttcagtc
    37261 aattggtctt ttaattcttt ttctgacaac ttcattttct aaaaccttct ttttcaatta
    37321 atattgcttc cgtgcttgaa tacgttgaag acttgcagtt ataggaaagg caagtcccat
    37381 tccaatcaga ttttggaaga tgtttcctgg tatagaagcc actccagccg gccaatcata
    37441 taaaatccaa ccggcgatac catagccgat gatcataact aagcttccta ataaaagccc
    37501 taatccccac atacgagtag aagatttgct gaaagaacca gcaacatatc cttgtaaccc
    37561 gtggatcact aatgaaaaaa ctgcccactg cggatatcct gaaatcaaat cgatcaatag
    37621 accactggaa gcaccaacaa ctaatccacc cgttggacca taaagaaaag cagcggtata
    37681 gatcccggcc tcgcataatg tcacaaatcc attcgtagcc ggtacaggga tcaaaattgt
    37741 taatgaaagg gcaactgtca acgcaatcag catagcatag atcgttaatt gcttagtttt
    37801 catttctcat tcctcctttt tgaataccgc cagaccagac acttccggta tgatcgttca
    37861 tcagcacgcc attagaaata caatgggcaa caaatttttt actttctgct actgctttgg
    37921 taaaatctgc ccctaacaca agattcgctg ttattgcaga agaaaaggca caaccggccc
    37981 cgtttactgt tgtagtgtcg atttttttat gagaaaatac ctcataatga tcaattgaat
    38041 agagaagatc cacagcttca tctccagcca tccttgtgcc gcctttgatc acaatgtttt
    38101 ttgttcctga agcagtgagt tctttagcga gatggatcat ttctgttaac gaagagggaa
    38161 gagcttgacc agaaagtaaa gcagcttctg ccaaattagg cgtaatcatc gtaacaagtg
    38221 gaaaaagttc ttcgatgagc tgcgaaatat acaattgatt gatcacagct tcagtttctt
    38281 tgaatgccaa aacagggtct aaaatgattg ggatattttg ttttgttttt atgaagtctc
    38341 gaacaaccat gattgcttca cttgaattca ataacccaat tttgatacca tctaatgaag
    38401 tcattttatc aatcgaaact aactgtcgtt taagcaattc caaagatata gattccagca
    38461 taaatcgctc attaatatct agtgccccta tagaagtcaa ggcgcttagt ccgaatagac
    38521 caaaattctc aaaagttttt aaatctgttt ggattcctcc accagcaaat ggatcagaac
    38581 cgccaattgt caagattctt ttcataacat tttcctccat gaataagagt ataacgaaat
    38641 tttcaaaaaa gaaaaacagc caattggcat atttttatct catccaattt aaaaaaacaa
    38701 aaagaaaaga aagaccaaaa tggatctttc tttccttaaa tagttaggac ttttgtgatt
    38761 ttaattcttt ctcgatttga agccgttgca ctttcattgt agctgttcgc gggattgcat
    38821 caaaatcacg gatgataggg acgttcaagc gaggaagttc atggacttgc tcccaccatc
    38881 gattccaatc catttcttta tcaggagcta aagcaataat cggttgtgga gaatgatttt
    38941 tatcccttac aatcactact tctgccaaaa aatctaacga atctaataaa aagtcttcaa
    39001 tagctaatgt actattgatc gtttcgatca aatccacttg ccgatctttc aaaaataggt
    39061 ggccatgctt atccataaaa ccgtaatctc cgctatccca ccaatcgcca taaacatttt
    39121 cctggaaccg tgcatcttcc ttgtaataag tcaaagcccg tcctttagac agtaattgta
    39181 tatgaccatc tgtgttttca ggtaggacat tcccaactga atctgtaatc cgagcgcttg
    39241 tcatgtcttc cagtccaacg cccatatctc ttgcatcact tgttttcaaa ctctctagtg
    39301 tatgagcctt aagaatcatt ggtccgcatt cactttggcc atatacttga agaaataccg
    39361 catcctgtgc catcgacgtt cgcaaaaatg tcttcattgt ctggttgttt atagcatcaa
    39421 aagtggagtg atagtatcgg atacccgaaa aagcttctgg atgctcctta gcagtaaaac
    39481 gccactgaac aaagttattc ggatgggtct ctagtgcaat tggccggtga gcttccaaca
    39541 tatgaacaac ttttgaactt tgtgcgtttg ctaaaggcat cataggaaat cccatggaca
    39601 tcaaagaaga gataccaata ttgaatctgg aatgcactgg agagatgtga aaagcgatta
    39661 atttcttttc cgaaattttt gtgaaaactg ttttttgcca tttcgtccgc catcccatag
    39721 aatgagcaga atgacaaata agtttaggga taccagttgt accagaagta tgggtcatat
    39781 aagaaatttc atttttgtct aaaaatgatt gagaaacaga caaagcaggt tgttccatta
    39841 aataaagaat agga
//
LOCUS       DADGHT010000013        38667 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.013, whole genome shotgun sequence.
ACCESSION   DADGHT010000013 DADGHT010000000
VERSION     DADGHT010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.013"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(369..995)
                     /locus_tag="JX887_000602"
     CDS             complement(369..995)
                     /locus_tag="JX887_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256614.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(1290..1625)
                     /locus_tag="JX887_000603"
     CDS             complement(1290..1625)
                     /locus_tag="JX887_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAX1256615.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(1612..1896)
                     /locus_tag="JX887_000604"
     CDS             complement(1612..1896)
                     /locus_tag="JX887_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAX1256616.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(1952..3475)
                     /locus_tag="JX887_000605"
     CDS             complement(1952..3475)
                     /locus_tag="JX887_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAX1256617.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            complement(3468..4643)
                     /locus_tag="JX887_000606"
     CDS             complement(3468..4643)
                     /locus_tag="JX887_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAX1256618.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(4647..4832)
                     /locus_tag="JX887_000607"
     CDS             complement(4647..4832)
                     /locus_tag="JX887_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256619.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(4798..6492)
                     /locus_tag="JX887_000608"
     CDS             complement(4798..6492)
                     /locus_tag="JX887_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAX1256620.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(6489..6962)
                     /locus_tag="JX887_000609"
     CDS             complement(6489..6962)
                     /locus_tag="JX887_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HAX1256621.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(7031..7186)
                     /locus_tag="JX887_000610"
     CDS             complement(7031..7186)
                     /locus_tag="JX887_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HAX1256622.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            complement(7320..7700)
                     /locus_tag="JX887_000611"
     CDS             complement(7320..7700)
                     /locus_tag="JX887_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAX1256623.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(7704..7919)
                     /locus_tag="JX887_000612"
     CDS             complement(7704..7919)
                     /locus_tag="JX887_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256624.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(7922..8329)
                     /locus_tag="JX887_000613"
     CDS             complement(7922..8329)
                     /locus_tag="JX887_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HAX1256625.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(8595..10070)
                     /locus_tag="JX887_000614"
     CDS             complement(8595..10070)
                     /locus_tag="JX887_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HAX1256626.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(10060..10908)
                     /locus_tag="JX887_000615"
     CDS             complement(10060..10908)
                     /locus_tag="JX887_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein"
                     /protein_id="HAX1256627.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(10945..11307)
                     /locus_tag="JX887_000616"
     CDS             complement(10945..11307)
                     /locus_tag="JX887_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256628.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(11607..12231)
                     /locus_tag="JX887_000617"
                     /pseudo
     CDS             complement(11607..12231)
                     /locus_tag="JX887_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(12228..12539)
                     /locus_tag="JX887_000618"
     CDS             complement(12228..12539)
                     /locus_tag="JX887_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256629.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(12583..12876)
                     /locus_tag="JX887_000619"
     CDS             complement(12583..12876)
                     /locus_tag="JX887_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256630.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            13070..13717
                     /locus_tag="JX887_000620"
     CDS             13070..13717
                     /locus_tag="JX887_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1256631.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            13778..14923
                     /locus_tag="JX887_000621"
     CDS             13778..14923
                     /locus_tag="JX887_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1256632.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(15004..15309)
                     /locus_tag="JX887_000622"
     CDS             complement(15004..15309)
                     /locus_tag="JX887_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAX1256633.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(15334..15765)
                     /gene="ruvX"
                     /locus_tag="JX887_000623"
     CDS             complement(15334..15765)
                     /gene="ruvX"
                     /locus_tag="JX887_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAX1256634.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(15762..16028)
                     /locus_tag="JX887_000624"
     CDS             complement(15762..16028)
                     /locus_tag="JX887_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAX1256635.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(16283..17008)
                     /locus_tag="JX887_000625"
     CDS             complement(16283..17008)
                     /locus_tag="JX887_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAX1256636.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(17369..17439)
                     /locus_tag="JX887_000626"
     tRNA            complement(17369..17439)
                     /locus_tag="JX887_000626"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17405..17407),aa:Gly,seq:ccc)
     gene            17556..18308
                     /locus_tag="JX887_000627"
     CDS             17556..18308
                     /locus_tag="JX887_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAX1256637.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNNLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            18324..18803
                     /locus_tag="JX887_000628"
     CDS             18324..18803
                     /locus_tag="JX887_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAX1256638.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(19054..20634)
                     /locus_tag="JX887_000629"
     CDS             complement(19054..20634)
                     /locus_tag="JX887_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAX1256639.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(20627..21370)
                     /locus_tag="JX887_000630"
     CDS             complement(20627..21370)
                     /locus_tag="JX887_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256640.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(21546..22322)
                     /locus_tag="JX887_000631"
     CDS             complement(21546..22322)
                     /locus_tag="JX887_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1256641.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(22570..23406)
                     /locus_tag="JX887_000632"
     CDS             complement(22570..23406)
                     /locus_tag="JX887_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAX1256642.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(23417..24346)
                     /locus_tag="JX887_000633"
     CDS             complement(23417..24346)
                     /locus_tag="JX887_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAX1256643.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            24538..24891
                     /locus_tag="JX887_000634"
     CDS             24538..24891
                     /locus_tag="JX887_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAX1256644.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(24965..25621)
                     /locus_tag="JX887_000635"
     CDS             complement(24965..25621)
                     /locus_tag="JX887_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAX1256645.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            25847..27781
                     /locus_tag="JX887_000636"
     CDS             25847..27781
                     /locus_tag="JX887_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAX1256646.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(27867..29090)
                     /locus_tag="JX887_000637"
     CDS             complement(27867..29090)
                     /locus_tag="JX887_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAX1256647.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(29084..30982)
                     /locus_tag="JX887_000638"
     CDS             complement(29084..30982)
                     /locus_tag="JX887_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAX1256648.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(30976..32094)
                     /locus_tag="JX887_000639"
     CDS             complement(30976..32094)
                     /locus_tag="JX887_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAX1256649.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(32177..33010)
                     /locus_tag="JX887_000640"
     CDS             complement(32177..33010)
                     /locus_tag="JX887_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1256650.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(33003..33920)
                     /locus_tag="JX887_000641"
     CDS             complement(33003..33920)
                     /locus_tag="JX887_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1256651.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(34147..35271)
                     /locus_tag="JX887_000642"
     CDS             complement(34147..35271)
                     /locus_tag="JX887_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAX1256652.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            35454..36362
                     /locus_tag="JX887_000643"
     CDS             35454..36362
                     /locus_tag="JX887_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1256653.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            36503..38116
                     /locus_tag="JX887_000644"
     CDS             36503..38116
                     /locus_tag="JX887_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAX1256654.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT        11704 a         7707 c         6342 g        12914 t
ORIGIN      
        1 ggaagagact gtgaagtcaa cgttttgacc tgattattag agaaacaaat ggcaaaatag
       61 ttcttcatat ttcgccgttt ttcgagcgaa tgccgagggg cagctgattg aacatcgttt
      121 atttggaaaa agggattgtg acaagacgtt tgtcacaatc ccttttttta tatcttatta
      181 attcattctt ttgttctatt cttcttcttc cgccatgaat gagaaaccca tatcaaagaa
      241 ctataaaggt tatcaaaaca gcgtttatga ctaaatgaat tagagttatc tatcactatt
      301 tttcaagcga tttaaaccaa atggcataca atatggcata caaaaacttc aataagccgt
      361 gggggttttt aaatttcttc ttgttcttta aaatcaatga gtggagctac ataatttgaa
      421 tccacttttt caaacgtcac tttttgcatc gacgaatgtt ttctttccca agataacgta
      481 aatagatttg actctggact tataaagtct acttcacctt ctagtattac tttcttatgc
      541 aaatattcct ctaataaata tagacttgct aaagcataca acacattttc caaatttgct
      601 tccttataat ttgaagaacg accatgtttt actctgttat atattttcca ccaatctggt
      661 gtatcttcag gccacccatc tccaaaaggt tttagtgaag tcaatgttaa agaattcata
      721 accctaacac cattatccaa acacattaat tcgctagatt taataacagc tttaaaatca
      781 gttatgcttt tattgctact gctatcaaat ccgcaaagtt ctttgaaaat aatctcacac
      841 tccgaaccaa tcgctagtag tagtttttga tattcaatag agaatgtttt gaaattattc
      901 tcatcgagca tcacaaaatc tgtggtatta ataaactcat tttctaaatg tagataatac
      961 ttccaataaa aatttgtaaa ctctgctttg tccattaaat cacctctttt gaattataac
     1021 aaaaaaaaca cgtccacaac agacgtgttc tttgatttct acacaatcag cttgccaaaa
     1081 ccatccaatc agtcctagca tgcctgtatt aaaattgaac gttcatcatc tatcatcttt
     1141 cttagtccag catgtttgca accacaccta caattttcag tccaacaata gatttcgact
     1201 agctaagtct tgcaaaattc aggcagctaa cccttcattt actaccttaa ttatactaaa
     1261 tacccacaac gtttacaagt gtaatcattc taagaaatct gtttagctat gatcgttgta
     1321 taatctttaa acgccgttcc ttcattgatt gaaataattt tataactctt gtttttccaa
     1381 gctactttca tatcgtttgt tagttcataa tcttgatcgt atcgaataat aaacgtcaac
     1441 gttccttcaa gaatggtacc tacactagca agcacgtctt ttagcatttg tgaacgcaca
     1501 ttagcccaac attcaaatac agtttcttca ctatccacca tctgcccatc ttcatctttt
     1561 acccgttttg tctttttaaa cttgactctc tcagtcaatt catttacatt cttaatgatt
     1621 ggcataataa gcacctctca tttgttgtac taatgcttgt accgttactg gtatccgttc
     1681 gctgctggct tcttgacggt tcaaatacca atgttgagta agtaatgaca ccgccaaatc
     1741 aaattgctga taattatcca tatctttatc cgttgcgcta ctatcaatag cactttttat
     1801 atattcgcct gctgtatcaa tcaattgttg aataaagtca tcatcaatag tgtgatcgat
     1861 ccgcatactt ttttttatgc tatccaaaat taccatttta tctctcctaa tgaaaaaaag
     1921 gcagtgggat aaaccgccgc ccaatatttt tctatacttt tggtgttaca actggcgtaa
     1981 actcaatata cactgaagca ttttgatcaa ttttcttata atcgttgcga acgatcactg
     2041 caagtccttg tgagtagtaa tcgaattttt cccattgagt cgttacttga tttctacgag
     2101 caacaaagat agattgtgca atatccccca taatcatagg gaatgttcca gctttaggat
     2161 tggcaaacaa tgtatctgca atcaatacta ctggcatacc gaataatgat ttaccactag
     2221 gtgctgtcac atcgggttgt aaaatgtaac gtccatctga atctttcaat gtatctaggt
     2281 ggtaatatcc gctttggttt agaattacca ttttatttaa tgctgggtct aatgccacat
     2341 tgtatagttg tttcaaatcg tccaacgtag cagccgtttt cttagtgaat gtttttaata
     2401 aatccatgat atgcttattg tcagtgtttt ctaccaattt cgctaactga tctttgacct
     2461 cttgtacaat attcactgct gaatcttcca caacctcatt tgataaggca atcttaccag
     2521 cacgagtttc tactttataa tcaactgaag taaacatttc agcgtcaata tcaccaattt
     2581 cagcaagttc agcttttgtt gctaacactg cttgttggtt agttgctact ggatatttac
     2641 cttgtccatt tgatactgtt tttactgttg catattgagc taagttataa tttgaacgtt
     2701 tcaaatcaaa gacttcaccg attacttctt cgggaacaac tgccgctgca tttacagtag
     2761 tgactccatc acgcacttcg ccttgtgaac ggatatattc ttcataccca cgcaattctg
     2821 ttttttcgtt atcgattaaa gttttttcca tgttattact ctccttttgt gctttagaag
     2881 tggattctaa gctattgttt gtttgttttg cttggttgtt actcataaac gattcgtaag
     2941 aacgcttatt tacttggaca tttgatgaat cataagcggg aacggtcacg acactaattt
     3001 cattaagtgc tttgatttta tctattgatc gttcaattgt gccatcttct tttttgtcga
     3061 atgaatctaa tccaagcacg aacccaaagg acatagaatc aacaacccct tttgagatat
     3121 tctcatacac atcatttgaa taggtcgtgt cggttagctc tgcttcaaaa tgtaatcctg
     3181 tatcatcgac attcaatttc aacgtacctg ctttgacact agctagtggc tttgaataat
     3241 cgtgtccata taataagaac acatttgata aatccacctc ttttaatgct tcgggtgtaa
     3301 tcacttctac aaagccgcct aaatcttttg acggttgccc gaatttcaac gcatagcctg
     3361 aaatagtttt gccgtctgtt ggttgttttt cattttcttt ctctactttg ggagaatcgg
     3421 ctgttagctc agcttcttct gtcagccgtt tttccttttc ttcttcatta ttcaactggt
     3481 gtaactcctt cctgttcttt taattgatat ttctccaacg tatctaaata cgtaaagttc
     3541 aaacttgcta gtaaacgatc gccaccatcc atggggggta gccccatttt cgaccgcccc
     3601 tcattaatcg tgagaagtga ccctttgacc tgatccaata cattttttac ttttgtttca
     3661 ggatcagtct ctagtaactg atcggaatta aagcggatat tggtttcaag tttcgtatct
     3721 aattcactca caaacacatt aaagtaatga atcagcgtac tttggatata ctggagatta
     3781 ctttgaacgg tgctagaatg ttcattttca acgcctaaac gctcaatcgg tacaccaaac
     3841 gccttggcaa tttgttttgt gttccaatca ttggaattga taagcttcaa aacatcggtg
     3901 tttatttcta atgttttgta gtccattgtt tcatcaagaa tgatcgttct aagagcatta
     3961 tctccactac ttgaaccgtt ggcttcttca aacttttcac gaattgcgtt ctttgctgat
     4021 ccgtctaaat ctgacttatg aaccttcaaa atacctgacc cactgacacc acgagtaaag
     4081 aaattgtgca atgtgcggtt gccagcttgt tgaattttca gttcatcacg taacgcataa
     4141 agtggtggta atcctgttaa accatcttgg gtgaaatatt tgaagtgcaa aatatcgcta
     4201 gacttcacac gtcttttttt atcaccaatc tgataagaca acgtaccatt atctaattga
     4261 gtaaccgtta cacttgagtt aggtaataag tgaatttctt ctaccttttc accgttgcgt
     4321 ttaatctctg caaagctatt accgtttagc aacatattga ccgccaaagc aaactttaaa
     4381 tgccaaccat ccatttctga attaggtttc tcgtttagta acttcaccag ttcattatca
     4441 gcttgtggca tattgttttt gaccaattga atcggacttg aagcaatatc actagcaata
     4501 attcgaacgg ctgcaaacac atcactattt cttaatgcac gaacgcttgt aaagctggtg
     4561 gtgtaatcat ccgattggat tgataccaca tgttgtagga aaggatctcc cgttgtattt
     4621 tgtctcgctt taaaaaatgc catcttttaa cctcccttct gttctgtatt tagcatgacc
     4681 gctaccccaa taagcactat gcccagcgct aacaagccat agtagacatt tgttagtaag
     4741 gtgatagcaa ccaacacaca caccaatcca agaagtaaaa gaacggtatg aatgtaatta
     4801 gaaagaaaat tcttcacttg tataaaattc attgtctgct ttcgctcctt ccgttgtggt
     4861 gaagtaatcc attgcaaaca cataggcatt gattaatgca gctattggat caattttgtt
     4921 actgttcttt gatttattaa tctgaatgcc gttgttatcc gtttttaaaa tagcgttgtt
     4981 cactgcatgg gtgagaatcg tatttttatt gtgaataacg ttgccttcat aaacttgttc
     5041 tctaaaagtt cgggtcggaa cgtttagagt aatcgttcct tgtcttactt ctaacattgg
     5101 gtagttggct ttttcagctt tactgataag cgaattagcg ttatacgggt cataacaaat
     5161 ccccatacat tccaaatcat tttcttgaat caaatcttga ataaactgaa atacttggtc
     5221 atagtccacg attccacttt ctaattgagt aatggaacac tcaccagctt tttctagttc
     5281 tcgataaggc aaaccgtcgc gcttttcttt gtcttgaagc ccatatttgg tggctacaaa
     5341 gctatgtgaa tcacaataaa gttcgccgtt atctagcggt acgatccatg aaacgctagt
     5401 taaatcatct gttttagata aatccactcc gatataaacg ggcttgcctg taatatcttg
     5461 tggttctact tcggttgcct gccagtcttc agcaatcata tagctgtcct cactcgcttg
     5521 tctccataaa ttgaagtttt tcaccaatac agaattaagg ttattttgtt tcaaagcaag
     5581 gttcacatca tcttgaatgg ttggaatcat tacttttttg atttcttcac tttcaaaaat
     5641 cggattggct ttgatccatt tctcttgatc gtgaatttct tcgggatcgt ccaattccca
     5701 tatcgctata aagtacctgt cggcttgttc ttcgcctttt agcacacgat ctaacaataa
     5761 gtattcctcg tacataggaa cgtttaaatc aagcccagcg gtactaataa cacacaataa
     5821 gccgttcttt tgttgggtca ttcctgactt aatgacgttg tacgttttac gagtttttgc
     5881 ttcgtgccac tcgtcaagaa ttgcggttgt tggtgcaaac ccatctagcg tgctggtttc
     5941 actagccagt gccatagcga acgaattaga gggcaagtgc tgaatcttag agttcataat
     6001 tttcagttgt ggtcttaaaa acttactaga cttgaccacg tttctaagtg aattagacag
     6061 catatcatag cccaatttag cttgtttcaa agcgttactt acaaacaata cttgccttgc
     6121 ttctgctggt tcttgttcca taatcaacgc attggcagcc atgccacttg cgatatacgt
     6181 tttcccattc ttacggctca tactggtaaa cgctcgattg aatcgcctgt aattcccttc
     6241 tttagtacgc cagccataaa gactgcctag aatgaatttt tgaaatccta acatcttgat
     6301 tgctttaccg tccgtagatg gtagcaactc aatgaattta atcgctttgg tggcttgttc
     6361 ttcatcgaac acataaggga agctatctga cttagaacgc tccaaatcgc ttatatgacg
     6421 ctcacacgct tggataattt tcttgggtgc aatcagctta cctgatagga ctttctcaat
     6481 gtaatcattc atgaattcat caactctttg aacgggtctt cgggttcatc atttttaacc
     6541 ttgttcaaag ctagttttga tcgtgattct aaggtcatac ctagtgaggt ggcttgtttt
     6601 ttcaaatcac tcatagcttg tgattgaacc cgaaccgctg gattggcttt ctttactccg
     6661 ttttcgcatg tgataaacgt acctgatttt cttatctcgg cttcggctgt tttcattcga
     6721 gcaaaggcta aacaataggc taccaatgaa ccataatctg cttcactcaa tggataatct
     6781 ttttttaatg ttggtacgat acgattccat tcacttctag cgctcgctgc catccagtca
     6841 gggggcgtga tatttattaa tggttgctgc ttgaacaatt cttctctagc gtccacacgg
     6901 attgcttttt cttcacttga tatattgcct tttgtatcgt gtaatatttt agggtgtccc
     6961 atgttgtcct cctttcagac aaaagaaaaa ggaacgtaag caattaagct cacattcctt
     7021 cgtttttcga tcagaatttt tctttatcta atttatctat ataaatgatt tttccgttct
     7081 gcatttgaat ggtcacttga ccaaaatgag gtaactcaat ggtgcgctgt ttccctgttt
     7141 tatcagtaat aacaattgta tttttcaata aatctcctac tttcattata tactttttca
     7201 cttgtgatta caagtgtaat cgttatttgt aattaccctt atgccttttc acaacggtta
     7261 tttgtaccaa aatgagtagg catcgattgt cagtaagttt cacactatgc ccccttaact
     7321 caaagggtac tcttttctcg tctttgtctt tcattggctg tcttggaatt atggtgtgca
     7381 tggcataaag aacgaaaatt agtttcatct aaccgtctat tccaatcatc ttttagttca
     7441 attttgtgat ctacaacatc agctttcctt atcaagcctt cttctaggca atcctcacat
     7501 actggatgat ttaaccgata caagtatgaa gcctttcgcc atgttctact ttgatagaat
     7561 tgaaaatatt taccttcgct ttgctttctt tcttcacgct taattgccgt ttgctttgct
     7621 ttatgcttcc cacaatactt ctgcctataa tcaatcaatg ttttacatcc agcatgatta
     7681 cattgttttt taactgccat agattaccaa ccaaagcgat ctcgttcgtc agaatcatct
     7741 tgttcccatt ttgatttgta ttcaatataa ggcgaaacta tcttcaagca cgttccgtct
     7801 ttaaaattaa ctttagtgat tttatcttcc tcaaaactaa taaagtctac atcttcttga
     7861 gtgtttgaat actcaatgtg tttctcacca tcgaagtatc taatactttc catatgcata
     7921 attattctac ctccaataaa ttagttatca attcatcatc tgttagtagc aaagccaaga
     7981 acttatcatg gatgtttaaa aacaaattat cctcattcga tgtaagctct cgttgtctcg
     8041 ctcgatcata taggttaagc agacaattaa attcatccat tagctcacct gtatcatcat
     8101 agttgccact atctaccaat gatcccacta ctagcgattg acaccacgct actgactcct
     8161 gcagccaatc aggttcttct tccattatct ttaatacttc tggatcaaat gtggaataat
     8221 cttctgttac caatcccaca ctaaatgcca gcgtgttcat tagaaaccga tccatttcat
     8281 ctgtatattg aaagttcggt gctttgtttg ttgaaataat attgagcatt tactttcctc
     8341 cttgattcgt aacacgtggt aacacctacg taacaggtac ccgttaccac tcaatcccaa
     8401 cggggacaag ggttctagcg ttttggtaac aggtaacggg taaaatccag taacattatt
     8461 ccccagcata ttagctaact atttcaaaag ttttaaggaa ataaggtgtt accccgttac
     8521 caaattgctg tatcccttgg ggcagtaagg gtaaactagt aacgggctag gtgttactga
     8581 cccgttacta cccgttactt tttgtacttt ccagctcgat ttttattttc ataggcattt
     8641 gacttattgt aaaatcctcg tcgtttattt ctttttggca gttgcttccg ttcccaacca
     8701 ggaatactgc taataatcaa ggcaatcttt ttagtttctg catctgatcg accattcaat
     8761 aaatcctttg cttgtttatc aaaaacagct tccaaaatat cagcggtgag tacgctatca
     8821 actaaataaa actcttgttg catagtagct ccattataga aatgctgtaa atttttctca
     8881 ttacatttac tgtcaggata gttctgataa taagaacgtc tcgcccacgc tggagcttct
     8941 tcccatttat acgggatttc catttccaaa tatttagtga ttgcttcttt aattggattc
     9001 tccatcttgg catcctcttg atagtctttt gcaatttcta agacttcttt atcttcatcg
     9061 ggactaaaat agattcgttg tcctttatca aaaagcacct ttgcttcagc taacacttga
     9121 agaaaatatt catcctttgt tttaaacgga ttcatctttg gcttattctt acaaggcaaa
     9181 ggataaaaac ggcggtttcc tgtatcatct ttcaaatact gcccatcatt cgacgttcca
     9241 ataaatacac attgccttgc ccaagctatg acattccgac cataaggagg tctaatttta
     9301 tcgatcttgg cactgatgaa gttttttatc tgttcaattt tagttttgtt cattgaagat
     9361 aattctccaa gttcaataat tacattgcct tgaagctgca tataatcatc tttcttttca
     9421 cctagcgaat ctaatgaatc ggtgaaaaaa tcatccgtgt aaagtaatgc tggaacggta
     9481 ctcttaccaa tcccttgcgg tccatccaaa actggaacga tctcaaactt tattcctggt
     9541 ttatagatac gtgcgactga tccgactatc caacgttttg ttacttctcg tgtgtaaagg
     9601 ttgtcgtcta cccctaaaag gtcaataaac agtgtttcca gtctaggctg ttgatcccat
     9661 ttaacttttt cgatacgttc ttttactggg ttgaaaacat tctttctagc cacatttact
     9721 actgctttgt gtattttgtt gtcatcaaaa actacattgt agttttcttc aatatatgcc
     9781 gttaaggcat cctcaaaact gtcttcccat tctccagcgg tacgattgat ccaaggagaa
     9841 tcttttaata ggtgaatgta tccgctaaat tcgttataag caattgttcc agctaaattg
     9901 ctatcattgg ttaaaatcaa ttctgcattc acaacactgt tacttttaat ctgatcgtct
     9961 ttattgcatc ttaatcgtga catccaggtt ttcaattcaa tgatattgtc ttcacgctcg
    10021 ctggcttcgg gaaagtctaa aatactatct aatttatgct tatgagccat gagctttccc
    10081 cctcaaatct tttttaatca tcgatcgaat aatttgattc acttctttat cttttagcgg
    10141 tggttcattg tacgcatttg ctgtataaat caattctgct aaagtttgat tatctacacc
    10201 gtgccatagt aaccaaccgc ataacttagt taaatgatcg tttctactac cttcgccagc
    10261 gccttgaaca atcatatcta atttttttgc tgtccctgtt tttgctacgg gtcggtattg
    10321 agtctttatt tcttgcggtt tttttagcag taggttcact agccaatcgg gagctggtgc
    10381 aatattattt agagatacgt tttcaatagg ttcatatgct ctcccaacac ttcttgaaat
    10441 aatcatagtt ggcgctattg gaactccttt agtgataata tcaatcccgc ttaaactttt
    10501 acctttatca tcacgcccga agatatcagc aaatgcacct gtttcttgtt ggataattac
    10561 accatcagga attttaaaga agaaatggat tcctttacct ggtgtgattt ccgtataagt
    10621 agaaggaaat ggatcataca ttgaagcaag ttttttataa ttctcaacgc cgtttcgtgt
    10681 ttcagaatgt tgatctaggt caactaccac catttgatga tcttcaagca ttaacccaat
    10741 atttctagtt gcatcttccg tccaccattc attaatttga ttagaatcgt tagttgcatc
    10801 attccaacca ctagagcctt ttattggaat tttagttcca ggagataagg gataaattga
    10861 ccatcccgac ttttgtaatt ccgttgctgc ttgataatta tttgccaata aacctctcct
    10921 cctttttcaa aatactggta taaatcattc agacacctcc atgagcttca actgctcaag
    10981 ttcgtatttc aacccatccc gaacaaattc agcacctttt aattgattct gatactttac
    11041 ccatgtatta aatgttttca cccttgcttc ttgcatatca gtaatgttta accatgcggt
    11101 taaaatctga ttttttagct cgttgatttc tcgacaaatt attttgtgtt ctgcatgttt
    11161 tttgagtaca tacaaaactg ttagtttttc attgaatgaa tttccaaagt aggttttccc
    11221 gatattattt tctagttcag cgatcccttg attaatttcc tctaattcaa ggctatcgag
    11281 ttggtttaat agttttgttt tgtacatcta cttatgccct ccagttctta attgatagtc
    11341 gtactcgtca taagcagtga agagatataa cgctaatcct gcaaagatag ctatttttgc
    11401 aattaatggt aataagccga aaattccgcc gattaaaatg cttcctataa ttaagtttcg
    11461 tttcataatg gttccctccg attttttaat atggtataat cggaacaaag aatatcgggt
    11521 tttatcccaa ttaagttgcc tttatcctgt ccgccaagac tgttatggat aaggcttttt
    11581 ctttgttctc gatcatgtta atgctcctaa gttgtctgca attcagcaga acgattataa
    11641 attttctcac tcactgaaaa ctgcaaccca tatttttctt taacagtcat taattctact
    11701 gtctcatcta aaataggttc acgatcaacc aacatttcag gagtcatatc tttctttttt
    11761 accattttgg aatgaccata aatagttgat acagctttat tggctatcac attcgcttta
    11821 atgtagtcta ctggttttgg ttcagtaata gcgtggctta atttagtcat tgcttctttt
    11881 tggtgttctt tgtctagcat gcggaatact tgaaagcctt caagtcctgt ggactggcgt
    11941 agttctttga tgatgtcgaa aatccagtct tgaaatgcct cggcttcttt tttacggctt
    12001 ttgaatgcca tgcggtaaat attttttttc gttgatgatg tttacatctt gtgttctgcc
    12061 caatgaatcg atgaccttac tagtagtaac cccatcttta ggcaaagagt gaatggctct
    12121 agtaacctgt ttaagaccta acgcttccgc aacatctttc gccactgccc accattcatc
    12181 attaatatcg acaaatctta taatgtgtcc gttccaaatt tcagttttca ttcaacgtcc
    12241 tccagttcaa gccctagcaa gctcgctaac aactcaactt gctgatacaa aatttcttga
    12301 tactcttcaa tagaaagtcg ttctttaaac tctgcttgta ctaaatcgtt caagccacgc
    12361 aatactccgc ttaccgttgg ttcttgtggt agcaattttt gatagtccat ttgttcgtac
    12421 aaacattcaa acgtttcttc tagcgctttg ccttccaagt ttgctaattc tgccgctgtg
    12481 tcttctgtaa gaattgttga taatactttt tcgattgctt tattttgtgt cgattccatt
    12541 attatttcct cctattaatc cctttgcccc cacggcttgc gtttattttt ggtattcttc
    12601 cataaagcga tcacattcat cttgtgaaat tcttacgact ccatcaacta taatcaactt
    12661 taaaccgtta ggaacatatt tctgcatcat agtattgtat gaaacgttca tatacttagc
    12721 agcttgtgcc ttgttcatat attttggaaa ctggtacttt ttttctaata atgaaagtaa
    12781 cgttccttga gtttgctcta cttgttgaac aactcgatcg tcaataattt taaaagctgg
    12841 atcatcaagc gtgagtttgt caatttttaa ttccatattt atcccccctc gttagcatac
    12901 atttctatac aaagatttta aaaaaatgca agaggctctt gaatacattt ctatacctct
    12961 tataaactca atataccatc ataccttttc atttgcaaga attttaacat acttttttga
    13021 acttttatgt ttcacacata tttaaatcgt gatatagtag agaaaatata tgaatggtgg
    13081 tgaaaatgtg gctagaaaaa aataccccga agcagtggag acaggacaaa gaattagact
    13141 ggctagaatt gaaaagggac tctcaatgga acaacttgga ggtaaattat ccccaccggc
    13201 cagtaaaggt gccgttagta attgggaaaa tggctataat cttcccaata acaccaggct
    13261 taaacaactt tcaaaggtat tagatgtatc cactacctat ctattaaacg gatcttatac
    13321 attaagagat atgcatatga tgcccgaaat taagcgaaat gtgcttgaaa agcaattgaa
    13381 aaaaactatt gaaaaaaata actctataat tgattctaat ctttctaatg ctatcaataa
    13441 catcgaagaa gataacctga ctgtctcaca gaagatttat ttaacaaacg caataaaata
    13501 tcttaaaaca ggatctcgaa ttgaatttcc tgacgggagt accccaattg cttatctcgc
    13561 agctcttcta aatacgcttt tacgatatga ctcattaatt aatgattcag aaaaaaatac
    13621 agatgagaaa aaagagtatc aagaatttta tgaaaatgat cttctaaaag agttcacagc
    13681 tcttgttact gagctaaata aacactattc aaaataataa taaactgcct cctccaaccg
    13741 cccccacggc ttgctacact atggagggaa aactattatg gcaacattca agcaatatga
    13801 aactaaaaaa ggtaaatttt ggctctatga agcctatctt ggaatgaaca aaatgactgg
    13861 caaacctgat aaggttcgta gacgaggtta caaaacaaaa aaagaagccc agcttgcctt
    13921 gtcacgcttg caagtggact acgataaaaa cggtattaaa aaagcgaaca acgaaacgtt
    13981 taaagaagtt tatgacttgt ggctagaaac atataaaacc actgtccgag aagccacctt
    14041 catgaaaact gaaatcaagt ttagaaagtg gattcttcca aaatatggaa atcttcgtgt
    14101 gaatgaagtc acggtaaaaa aagcccaaca aattgtaaat agctgggctg aaactactga
    14161 ccaatacaag gtacttcatt caacttctaa gcgtattttt agctacgcta tcaatcttgg
    14221 gattattgag actaatccac tagacaacgt attaatgcct aaaagaacca ccactaagca
    14281 taaagaaaag gtcaaagttt acagtaaaga acaactgatc accttgtttg attacctaaa
    14341 cagcaaacct gaaacttatc gaaacgactt tgataaaacg ttactacgct ttctctttta
    14401 tagcggggtt aggatcagtg aagcccttgc attgaattgg tcagacattg attttcaaga
    14461 aaatacggtc accatcaata aaacactaag ccaatccaaa aatggctata aaatcagtga
    14521 tcctaaaact gattgtagtg ctggggttct tccactagat gaaagaacaa tttctatatt
    14581 aaaaaaatgg cagattaatc agcggaaata tatgctgaca cttggtgtaa ctgatccgac
    14641 tatgattttt tgtggtatct ataaagaact aatcacacac cacgctattt atgcaagatt
    14701 gattactatt tgtgaaaaag ctatggttcc atttctcggt gtgcatgtag caagacacac
    14761 tcatgcttca atgctcttgg acgctggagc tactatggta gaagttcaaa ctagattacg
    14821 gcatacaaaa attagtcaga cgatcgattg ttacggtcac ttggcaaaag aaacgaaaga
    14881 aaagactgtt gaaaaattag tacaacactt aaatattgac tagatggcat acaatatggc
    14941 atacagtaaa aaataaaaaa aggagaaacc ctatcatatc aaggtttctc ctagctttat
    15001 agtctattct tcttcttccg ccatgaatgt attgaatact tcttcaatca tgtcccattc
    15061 tgcgtctgtt tcgatttgtt ctaactcgcc ttctgttcca tcttcgtttt cgatgtatgc
    15121 ataagcttgt aattctacat cttcatcttc tgaaacacca gcaggatata aaagaacata
    15181 gttacgtcca aattcttctt gtccgtcaac tgttagtagg atttcatata atgtttcatt
    15241 tccttggtca tccaccaatg tgatgtgttc gtgtccttca tggtcgtggg aatggttatg
    15301 ttctgtcata agattacctc ttttctttta ttattaaaat aattgcttac ctgagccgtc
    15361 taaataattt tgtaagatca tcacagctgc taatttatcg atgacttttt ttcgtttggc
    15421 tcttgaagta tttgcctgct ctactagcat acgttctgcc tgaacagtgg ttaatcgttc
    15481 atcttgataa tcaactggca aggagaatag ttctttgatc ttttctccgt atgacatgga
    15541 agcttctgcc cttggtccga tggaattgtt catattttta ggtaatccaa ctacaaaccg
    15601 gtctacttca tattgtgcta ctaattcctt caaccgatca aagccaaact cttcttctgc
    15661 ttcattgatc cgaatgatct ctactccttg agctgtccag ccaaaggggt cactgatagc
    15721 aacacctact gtcttagaac cgacatccaa gcccattact ctcataaatt cactccatga
    15781 tttgagaggt agtccttgac aattacttcc atgatctcat cgcgttcgtg acggcgaatc
    15841 aaatttcgag catcacgata acgaggaatg taggacgggt ctccagaaag caagtagccg
    15901 acaatctgat tgattggatt gtagcctttt tcttccaaag cccgataaac aatcgctaat
    15961 gtttcgctca cttctttttt gcgactatcg tcaaaaccaa aacgtacggt ttcatctgta
    16021 aaacccatga ttctacacct ctttcccgca aggtaattcc agcttacctt ctacaacctt
    16081 attttactcg aagaaaggga aaactacaaa caaatattcc aaacttccga ataaattaag
    16141 aaacactatt tgtatgtttt tttccttttt tctgtagctt tatcaaaagt actcttttca
    16201 taaagtatac gctatatttc tttgaatgta tgtttttaca caattttttc ataatattca
    16261 taaaaaattc gaatagctgc tactaatttt ttgtttttgt tgcttgtcct gtctcataat
    16321 tgatcgtgta gccatcttga acattgtaga taaagacatt gaattcaatt tttttgtctt
    16381 caatgctttc tgcttccaat tgcactcccc tggctaccag ttcattcccc tcaaaatgag
    16441 gagtgacacg gtagcgtaca tgatgatttg tttctttgat atatgccgca atatcatttt
    16501 cgtgagcaag catgtatgga gcattcaacg aacgtgtccc tgtcatcaag tttttaatgt
    16561 tgttattttg accagtcagc tggaaaccaa ttaaatggct gcgattatat aaccattgcc
    16621 cgtcacttaa tttcttttgt ttccaacctg tcgggtcaat atacaaaggc tctctctttt
    16681 cagtagggaa caaatctttt ccaagcatag cattggcttg tcctactctg ttcaatttat
    16741 caatatttga atagctttcc catgttcctt tggaaaggct aagatcctct tttgtaaatt
    16801 ccggctgatt cccattgatt tctatttctt gatgttttcc atcatattct ggcacatccg
    16861 ctacttgaga agcttgtggt gtggaatcaa aaatagttgt aatctgctga aagatatctg
    16921 aatctttttg tgtggtggaa acaccgaatg cccctgcaat cacagcagcg acgatcccca
    16981 cgatcgcctt ggttgttttt ttgctcattt ctttactcct ttactaacag ctccctaaat
    17041 cttaacatat gttcccctat aaataaatac tagaaagaaa tagaaacagc aaaaaataaa
    17101 acctgtttta agatggctta aaaatacaaa aaagagacgg attcctcgtc tctaatcagt
    17161 caccactcta tctgtaaggt atttattatt attcaaaaat tttcttcata ctcaagacaa
    17221 tacactgatt tcacaaccgc ttggtaaacg gtgcgcaaaa gcttgcatct gcggtaataa
    17281 gtccatccaa gttaaaaaca taagaagttg tttttgcttg gctgttctta ttacttgttg
    17341 cagagcagct ttttcacaac ctattttaag cgggtgacgg gaatcgaacc cgcgacatca
    17401 gcttgggaag ctgggatttt accactaaac tacacccgca atacaaaaac agtatacgcc
    17461 tcttttattc cttcctcaag tttttttatt ctttacgctt ctggtatgtt ttgtagtaaa
    17521 ataaaactaa tcaatcaatt attggagaag atgctatgac gggaaaagaa ttagatctgt
    17581 tgctggacac ttgtttactc gctgggaaaa tcatgatgga aagcaatgcg gagatgtatc
    17641 gggtagaaga tacgatgagt cgaattgctt tagcttctgg aaatttccgt ttggtcagct
    17701 atgtcactca aaccggtctc tttattggtc ttgatcgtac ctcgaccatc cgaatggaac
    17761 aaattaccaa ccgttcgatt aatttagaaa aagtagtaaa agtaaataat ctttcacgta
    17821 aatatgttgc ttcagagcta acattagaag aactttactg cgaactgcaa gcaatcgacc
    17881 gagaccgttc tttctttcct gtctggttgc aaatcgttag cgcggcagtg atcagtggaa
    17941 caattatggt gttatttggc ggaaagatga ccgatttacc tgtgacttta gtcattggag
    18001 gattgggata cgcagcttat ctatatagtt tgaaattttt tagaatcaaa tttttatcgg
    18061 aatttttatc ttctttattg attggcatag ccgctatcta cagcgtacgt tttggcttag
    18121 gaagcaatca ggatctaatc attatcggat gtgtgatgcc tttagttcct ggagttcaaa
    18181 ttacgaacgc tatccgtgat ttgctagctg gacattatgt ctcaggagtt tctcgcggaa
    18241 cagaagcgat gatgactgct acgatgatcg gttttgcgat tgcttttatt ttccagcttt
    18301 tttattagga aaggaacaca agtatgggga cgatatttat tcagttttct tttagttttt
    18361 tagcgactgc ggcatttgcc gttattacaa atgtacctag gcgttcattg atttgttgtg
    18421 gtctttctgg tgcttttggc tggatgatct actggatctg tgttcaaata ggcggatctg
    18481 ctgcttttgg ttcattgctt ggttctttag gagtagcatt catcagcgat cttttctcta
    18541 aacgtttgaa aatgcccgta acgattttca atattcccgg gatggttcct ctagtccctg
    18601 gtggtttagc ttatcaagcg gttcgaaatc tcgttactga atcctatcga gaagcggctc
    18661 attatgcggt ccaagcaatt atgattgctg gagcaatcgc tttaggtctt gtattatcag
    18721 aagtctttaa ccataacatc cgtaatttca aagtaaagcg tgacgcaatc atgatgaaac
    18781 gaaaaaaacg gctttttaaa taaacgaagt gtaacaaaga aaaggttgtg aaagagacgt
    18841 tcagccttga gcgatgacaa aatatctcac aaacattgcg acaagtaacc gcaggagcaa
    18901 taagaagtaa ttatgagtat taaaaaaagt tttgtaaaaa tagcttctca catttttaca
    18961 taaaattgac ttaatactga gaaactgact tttgaacacc ctctatctgt aaaaaagggg
    19021 ctgcgacatg atttttgtca cggcccctct tctttattca aattttttcc aaaacgttcg
    19081 ttgataataa acgatccata gagcggaaag tattagaact aaaccgatca caggaatatt
    19141 cactaaccaa aatggataaa acaaagccaa cattccgtat aagacgataa gaataatact
    19201 gatgatcaat gaacccatca tagttgcgac taaacccaaa cttcctgaac ctctgttaaa
    19261 taattggtta atattggtcc agttcagcag cagcaaccga taatctctag cgaaataacg
    19321 tagtgacaat aagtagcagc cgaataaaga accaaatagc aagctaggga taaaaaacaa
    19381 aggcagctga aaagacagtc cgcttaataa tgcgatccca ccagttaaaa aactctgcaa
    19441 tatccatccg aatctgaact tttcttttaa atattggttc atagagattg gcaaagaacg
    19501 gataaacaga aaattttctt gatccaaaga aataagattg ctgataaaag aagtctgatt
    19561 aactgttaag aaagccaatg cgatccctac caggaaaaca acaccgatta acttattatc
    19621 taaatcagtt aattttattt cgcctcctag ggcaaaagca agaataaaaa tgattggagt
    19681 taacaaggaa gaagaaagaa cttgcataat caaattaggt tcttttacta attgagcatt
    19741 gtaactaaat aaaagctgat gcacattttg gttcttttta tgggttcttt ttattttgaa
    19801 ctcactgttt gaatcagtca gttgctctgt aagctttggt actatcagct gttttacagc
    19861 aaggaaaaat cccagagccg tgatagctag tattccccaa cccaataaac cttgttgaga
    19921 aagtggctga ctggcagcat catagaatgg caataatatc gaaatcggat gccgatctgt
    19981 taactcattt tcaatagtcc ccgtttgatg attcatccac atgattccag caaatgcgat
    20041 cagcatcgag ctgccaagca agatactaga aactgttttt ctatgttttt taaacactgc
    20101 tgttcgagcc aaaccaaaaa caatcaaact agccagacaa aaaagaataa tcaaaaatag
    20161 agaaaacaaa aggattgaga taatgatagt aagcaaaatc cctagatcag ctcgccatcc
    20221 ggttaaaata aacatgacta gaagcggaaa aacaaaagga atgatggtca aagcaactac
    20281 caaaatcttt gctgaaaaaa cctgttcttg tccaaaaggc agaggcaaaa atacttgcag
    20341 gtcatttcct tcaaaaaaga tattataaat gactgatata ctttgagtta aacctaacat
    20401 accaaaaagt gccacgtaat aagtaaagaa acctggcaat ttaacaaagt tcatagcaaa
    20461 catagcaaat ccgtaaatca gtaaaaaaat cagccctgaa aaaagatttt gagacaaaag
    20521 atagatagtt aatcgctttc ccttttttcc tttctctctt gctttattcg tgagctgtgg
    20581 attaacatat aaaagattaa ctcgaattaa ttctaataat tgtcgcttat acatacggtc
    20641 catctcctgt cgcttgcctt ccagccattt tcaaataaat cttttctagc gtttcatcag
    20701 gtgagccatt caataattca ctaactgccc cctgataaat caattcacct ttcttcaaaa
    20761 tagccagttt atcgcataac tgttgtgcgg tatccaatac atgtgtagaa aaaatgactg
    20821 tttttccttt tgcggcatga gccttcatca tttctttcaa atcaaatgct gcttgaggat
    20881 caagtccttg caaaggttca tccaataccc aaatatctgg atctggcagc aacgtgccga
    20941 tcaaaatcgt tttttgacgc attccatgtg aaaaacttgc gattgtttca ttttgatgac
    21001 tatacatatc aaaaagcgct gtcaattctg ctaaacgctt ttcttttttt tgtgtgtcta
    21061 attcataggc agctgaaatc aagtcccaat attctccagc cgtcaattgt aaaaaaatat
    21121 ctggggaatc aggcacataa ccgatttttt gtttgatact caatcgattt tccgtcaatt
    21181 tcattccatc tactaaaatc gttcccgatg atggttcaat aatactaact aaacttttaa
    21241 tcgtagttga ttttccggca ccattatgtc ctaaaaatcc aaaaatttcc ccttgtctta
    21301 tcgagagaga caagtctttt aatgcttgtt ttttcccgta acttttactt acattgatga
    21361 attcaatcat ttctgtactc cttttgtttg ttattacttt ttattgtacc cttcgttatt
    21421 ggtggagtaa atgtcaaaaa gagtgcataa caaaaaagga tagaaacgac taggctgcta
    21481 cttgggttgt tctcttctac aggaaaacac tcttctaaca ggtaagatat gagtctttgt
    21541 tttctttaaa atgattcatt ttctatcttt tcttgcataa aattctttag tttatcaata
    21601 cttctctttc ccatctctag ttgttctcca tttgcaaatg ttactatttc gtttactctg
    21661 ctaatagatg taatgttttc agtattaatg atataagctt ttaaatcttt acataaatac
    21721 tcatattcga gtgatttttt atatttttta attgtgccgt ttacgagaat ctcttcatct
    21781 ttcaatacta ggcctatttt atttttataa cctggcatgc tcattagata aaggatttca
    21841 tcgtaatgga tatagtgatc gctattacca taacggacag ttgtccacct ttttttcgta
    21901 gcatgttgaa caggatagtt ttctttttct ttcaataagt aactttggat gcttttttta
    21961 tttttttcat aagtgaattc ttttatcaaa taaccactag gcgtaatctt tcgattaata
    22021 acagttattg ctttattcgg atgagacgtt agataaacaa ttttacactt ttcattcttt
    22081 tctctaagca tttcgcctag ttcgataccg ctataatagg cgttcaaatc gatgtctagg
    22141 aaaaaaatat ctgaggaata gatttcatta tttttaatga attcaacaaa ttgtataacg
    22201 ttcaatccct gaacgatctc aaatttccaa ggacttaata aaattctgga ttcttccaaa
    22261 atttctacta gcattttttc aaaaaccaaa ctatcatcca aaataaatat acgcgttacc
    22321 ataaaaagta cctccactcg atattttact atcaaaatca tttcatacaa cttttcaaca
    22381 tacatgttag gaataaattg taattctctt cacaatcttt tccaacacct ttgaaaccga
    22441 tatcaaatac tttcaggatg ctgcttctaa aataaatatc aaacaaatga atacatcatg
    22501 caaaaaaagc cagacaaccg acgtccttgc gtgtcagctg tctgagctat gtttatttat
    22561 tttgttcttt taaaaagaac gatacacata ctgatttttc ggagcagaga ctttctcagc
    22621 gtttgtaaca actacagatg ggatttcacg cttgaatggt tgataatagt ctgattggat
    22681 ggttccttct attttatacc attcatcatt tttaaccgtt actccttccg gcatatgcgt
    22741 caacaaacca aagactcctg aatctgccac acaatggata atgccgaatc ggaacaagaa
    22801 gatatctgta ttgctatcgt tcggtgtttg gtaaacaaat ccttcatagc tgattttttt
    22861 gccaatgaat tcgctagggt aattataaat tagctccata acttctaaat agttttcatc
    22921 tgtgatcttg atagtttgct tatccccata cttttctttc aactcattca tttggtctaa
    22981 gtagtctgat ttgttgaaat aaatactggt atccggcttt aagtattgtg tctgcatctc
    23041 cggatcccct actgattctt tacttactgg gaaattaaat cctttggctt ctacgatcgt
    23101 agtgtcgaga ctaactgttg gaaacaacgt ccccacgatt actggcaaag ctagcagtac
    23161 ataagcgatt ccacgttgat aaggttttga caacccatgg tcatgatcgt gctcgtgtgc
    23221 cttttcttct gcttttccgt ttttgaccca caaatacagc tgaactaaag ccaaaagagc
    23281 agataaaatc attgaaagaa tagctaagta gcgataatgg acattgatat attgatcgag
    23341 tttgccagaa acttgcaagt acatcatcaa ttcgaaatac ccagataaaa tcaaaaaccg
    23401 cagcatattt tccctcctaa ataaataatg tgaatccaat aacgctaagg gcaatcagtc
    23461 cgatcagcga taaaataaag cgtcctgtaa aatatcgttt catcatcagt agatttttga
    23521 tatcgaccat tgggccaaag accaaaaagg cagctacagg tgctgtgccg aacagactta
    23581 acaaagaaga tcctataaac gcatctgctt ctgagcaaag agacatcgta aaggccaata
    23641 acagcatgat gataatggct aaaatctttg ttgagccgag cgttagcata attctagttg
    23701 gtaaataagt ctgcatcgca gctgcgatta atccgccaat gatcaaataa cgacctgtat
    23761 caaaaaattc gtcgattgaa tgtgtcaaca catgcccagt ttgatggatc agctgatttt
    23821 ttggttcatt cttctcactt tgttcttctt catggacatg atgatggtga ttttctgcta
    23881 ctttagacgt gattttttct ttcaatacag cgtctttttg aaaataggca agccagacac
    23941 caatcacaag ggcaacaaaa aagctgccta tcacccgcca gcttgccatc tgccaagaat
    24001 tgccaaatgc gataaaagtg gaaaaaatca cgattggatt gatgatcgga gcagtcagca
    24061 taaaagcaaa cgctgtgtga actggtacgc cttttttaac aaattgatga acgatcggta
    24121 cgatgccgca ttcacatgaa ggaaagaaaa atcctaagat cgaaccagta aaaatagaga
    24181 agatacgatt ttcaggaagc catctcttca cacgttctgg ggtcaaaaat acttgtaagg
    24241 cgcctgagat aagacagcct aataatacga aaggtaatgc ttcaataacg atcgataaga
    24301 aaatcgtact catctgcaaa accgaatttg gaataaaaga aaacatgagt ttcctccttt
    24361 ttatttctag ttcattcgct ttgcaaatat acgcttttat tcaaaaaaaa caagttgctc
    24421 tgtaaatttt tacacaactc ttatttttta ccaaagcact tcaattgact ttttctgtta
    24481 ttcccattaa attaaggtct catacatatc acttctatca taaaagggag aataaaaatg
    24541 aaacaaacca ctaacttgac tgaagttcaa gacatactgc aacagtcatc cgttgccgtc
    24601 atttatcttt cgatgcctaa ttgcagtgtt tgtcacgctg ttcgtccacg actagaggaa
    24661 cttctcacac attatgatat tccggcactt catttggatg catttgaaac accagaagta
    24721 gctagtaaat ttgaagtgct gactgcgcca gttgtcctga tttttcatca aggaaaagaa
    24781 gtctttcggc aagcacggtt catcgacttt aaaaaaatcc gttatctact agatgaactg
    24841 acagcagaag atgattccct ttcttatgaa gaaatcttcc gaacaaaata atcgttgtcc
    24901 aaacagaaaa aagcgattga acaagtgaaa gttttgcctt catttgttca atcgcttttt
    24961 atttttattc tgctgtattt tcggaatgcg catttgcgtc agaatgcaag aaatagatca
    25021 aggtttgcaa ttcattcgtc aaatcaacat tttggatcaa tacatctgac ggagcattca
    25081 atcgagcagc ggtaaagttc aagattcctt tgattcctgc ttccgttaac tgattgacta
    25141 cttcttgtgc tctttcagcg ggtatcgtta aaattgctac ttcgatttgt tggatcttga
    25201 tttgttctga catatcttcc attggataaa cggggatacc gtctacgatg cgcccaacga
    25261 tttcctcatt cacatcaaaa gcacaactga tacgtatgct attactttga tggaatttgt
    25321 attttagtaa agcacttccc aagttcccta caccgatcag cgcaacattt gtcaattgat
    25381 cgtcgtttaa tgtctttgca aaaaagtgca taagatcttc tacatcataa ccatacccac
    25441 gttttcctaa ttcgccaaaa taagaaaaat ctcgacggat cgttgcacta tctacttgaa
    25501 cggcttcact taattcagtt gaagacactt ttttctttcc agcattattt aaaatcctta
    25561 aatagcgata atacaaaggc agtcttttag ctgtcgcctt tggaataata tgatctttca
    25621 cgaaatgacc tccacgtatt gtctaattac atctttgatt tctccatcat agcagtattt
    25681 ataggaaaaa atcaattcca ttgctcagat attgtgaaat tttattcttt attcatttat
    25741 ttatcatttc tgcaaatctc gcagtataat ggaatttatg gtagactact aattgaaaaa
    25801 tagtttttta tttgaggaga attcacaaag tagaaaagag gattccatga tattattaca
    25861 agccaatcag attgctcgcc attttggtgc agaagtctta tttgaaaaca tacatttaga
    25921 aatcagtaca ggcgctcgtg tcgctttagt tggcagaaat ggcgctggaa aatcgacttt
    25981 attaaagatc attgctggaa ttgaagcacc tgatgaagga aagatcgcta aaaataaaac
    26041 agcgactctc ggatacctcg ctcaggacac aggacttgat tccaatgaaa cagtttggaa
    26101 cgagatgctg aaagcttttg aacaagttag acaaatggaa gagcggatgc gcgagctaga
    26161 gattttcatt agcgaaggta cgccagacac acctgcttat agttcttatt taaaagaata
    26221 cgaccggctg caacacgatt tttcagatcg aaacggctat ggttatgaaa atgaaattcg
    26281 ttccgtattg catgggttta aattcgattc ttcattttat gatcagaaaa tcgatacttt
    26341 atcaggcgga cagcgcacac gtttagcttt agctcgcatg cttttgcaac accctgacat
    26401 tttgattcta gatgaaccaa cgaaccattt agatatcgag acactttcct ggcttgagaa
    26461 ttatctgcaa agctatactg gtgcattatt gattgtttcc catgaccgtt attttttaga
    26521 taaagtagtc aatgaagtct atgaattaag cagaagaaaa atgcgccatt acaaaggtaa
    26581 ctattcgaaa tatctagatt tgaaagcaga acagttagca agtgaatgga aggcttatga
    26641 aaagcagcaa acagaaatcc ataaattaga agacttcgtt gctcggaacc ttgttcgcgc
    26701 ctctaccaca aaacgagcgc aaagccgcag aaagacatta gaaaaaatgg accggctgga
    26761 tcgtcctcaa ggggatgaaa aacaagcaaa ctttctattc agtatagaaa agccttctgg
    26821 aaatgtagtc ttgcaaatcg aagatgccgc tatcggatat gataatgtca ccttatctga
    26881 accaatcaat ctagatatcc gtcgtcaaga agcgattgct ctagtaggtc cgaatggtat
    26941 cgggaaatcg acgttgctga aatcaatcat tcaccagatc ccttttatcc gtggaaaaga
    27001 aacgctaggg acaaatgtca ccatcggcta ttacgatcaa ggtcaagctg atctgcatac
    27061 aaacaagacg atcctagcag aattgtggga tgagcatcct accactccag aaaaagagat
    27121 ccgaagtgct ttaggtgctt tcttattttc tggcgaagat gtagaaaaac caatccctct
    27181 gctaagtggc ggtgaaaaag cacgggttgc tttagccaag ttagcgatga acaaagaaaa
    27241 ttttttgatt ttggatgaac caacaaacca tttagatatt gacaacaaag aagtattaga
    27301 aaatgcattg atcgattatg acggcacact gctttttgtt tcccatgacc gatatttcat
    27361 caatcggatc gcgacaaaag tcgtcgaact ctctgaaaat ggcagcaaag tctatctagg
    27421 agactatgat tattatttag agaaaaagca ggaagaagaa gaaatcgccg aattgttggc
    27481 acaagatgag ccagaatctg ctcctgctcc cacgaacaaa tctgattatt accaaagcaa
    27541 agaacagcaa aagcttatcc gtagccttca acgaaaaatt actcaggttg aagaagaaat
    27601 ggcgcggatc gatgaatgga tcgatcagtt ggaacaagaa atggtcgcgc cagaaaacct
    27661 ggaagatcac gtaaaactca atgagctgaa ccaagattta gaagctgcta gacaagatca
    27721 agaaacaaaa ttgacggaat gggaagaact aagcttggaa ttagaagaat atgaaaatta
    27781 acgaaaaaac caaaacagaa accattcatg ctgttttggt ttttcttttt ttattttatc
    27841 aaacaaaaat tccatattta cctttttcac caataagaag accaattact agtcattctc
    27901 actaaagctt ctaaataata gtaatcaccc caaatacaag gtgtatttac cccattattt
    27961 ttgggcttat tataaacaga ctgtgttaaa aagccatctt cttcttccgt tgtagcatat
    28021 ctttctttca attgtcgcat aattttccaa acagcagact ggtataagtt cttttctgtt
    28081 ttgtctaata gacctgattc tattaattct aataatccac aaaccatgat caccatacta
    28141 gatgtatctt tttcttctct gctagaatca tcaaagatca aatcccaata acaaatggta
    28201 tcttctggca accgattcat aaaataattg gctaatattt tgcttaaatc aaaatatttt
    28261 tgttctttca aataacgata acttaatgca aaaccgtaaa tcccccatgc ttggcctcta
    28321 gcccaacagg aattatcact ataaccttga tgcgtacttc catatcttgg ttttccatct
    28381 ttgacatcca tataaaatgt atgataagtt gaaccatctt ctcttactaa ataatctgct
    28441 gcattttgaa tatgagcctg agcagctttt ttatattttt gatttccagt ttcttcactc
    28501 gcccaataca ataatggaag attcatgcaa caatccatga tcattctacc ttgttgtgaa
    28561 ggatcactag gatctcccca agcttgtata actcctgcct tctcccaaaa acgctgaagt
    28621 aatgtttctg cagcatcaat tgaagcttcc ttcatttttc gatttcccgt tattttataa
    28681 tctgctacgg ttgataaaga atacaaaaaa ccaagatcgt gatgattagt gataatttga
    28741 cagtcaatcc tgtggataaa atctatatct gctttttcag ctgtttgttg aaataaagga
    28801 tcacccgtct tctcaaataa caaccaatta attcctgtcc aaaatccttc tgtccaacca
    28861 atattgtctc ttaatggata acgtcctttt ataggacact cgcttgggaa ttgatactga
    28921 ctgttactga tacgtttgat taacctctcc gtgtgtctgc gacaacgctc gatctcatta
    28981 ttccattctt tttccattaa ttctttataa cattcattta tccatttttc tggatgtatt
    29041 atctcttcaa acatcacttt atcaagcatt tccccaccag cctttagcat aattttagtc
    29101 tttttttatt gtttttattt tggatagtta gcccggttgt cccatcaaaa tcaattttgg
    29161 gacgattgtt ccatacttct aaactataat cccgatcttg atgagcaacc actcctgttc
    29221 cgagccaatg ggttcctttt ccaaatgtac cctctaatcc aggaataaaa gtgttttccc
    29281 atgtcatcaa gtttgtattg ggcaaaccca taatagctgt ggattttcgt ttaatagtat
    29341 cgtcacttaa acagataata cctgaaaagc cagcttcact caccctatag ttttccttgt
    29401 cttcttctat gattattcct tctttctcag gagaacattc aatagcaaac cctgtctcat
    29461 atagaacata ttctgtatct aattctactt tgtgtacgcg aatctgccag ccttcaaaag
    29521 gaataagcca agttctgatt tttgcctgta aagtaggttc ccatgtagag gcaagtacct
    29581 ctttcttaca tacaatgtct cgtacattat ttcgaacgat gaactgtcca taggttttga
    29641 tgctctcatt cttaaaactg gtcgtgatat atgtgtccgc tcgctgaatc cctagcattg
    29701 aatccattgc catttctgct ttcaattgat tcgctcgcgg tatcgaaaaa ccaaattgac
    29761 tagaataagc aaattttaaa tatttttcat tggtcaatgt atggaaattt ggccctaatt
    29821 gtcccgcatt caaaaaaaat gtatgtccat tatcatgttg tatgagcaaa ttggcttctg
    29881 aaagaagttt agttccttca cgaataggca taggcatttc tttagccgtc caatactcat
    29941 ggtcttcagg tagcgccaac aataaaaaaa tcttattcag ccataatgga gataacgtac
    30001 tattataggg ttcagtcaat gtcaattgag ggtaggtata accaatattc aggatacctt
    30061 tttcatcaaa tatttctttt tgcatccacc atcttatatt ccgattgact aaccccttga
    30121 tttcacctaa tttaaaaggc aaaagatcgg cccacaacat agctgaccaa aagcttgaaa
    30181 ctgcaaaacg ataaatcatg cttcgaccaa aaggcacatt tgcaccatct tccgcaaaaa
    30241 aatgaatata gtctctagaa aaatcaatag ctcggttctt atatatctgg ctaatgggct
    30301 tttctggttc tagtacgcta taaatcaaac cataataatg aaatgcaaaa ggattataat
    30361 aatcttggcg acctcttgaa ctgtctcgat accagccatt ttgaagataa caattttcta
    30421 tattatcaaa tgcttctttc agtgctgatt ctttaactgg ataaccaaat ttttggataa
    30481 ttgttccgac aattatctta aaaaattgcc aattaccatc tgcacattca tattcaaaaa
    30541 tttgcgagaa ccaatgaata atctggcttt tttctcctgt atctaatttt ttccataata
    30601 attgttcatg atgatataac gctaataaca ttgcgggcat ttctaccata cgctggtctc
    30661 tttcatgtat ttctccccaa taatcgggat gggaaggatc tgttccagct tttattcctg
    30721 atagaattaa tttcaaccat cgttcatcta attggtcaat tgcgggcccc gctccccata
    30781 aaacccgaga gaatccttcc attcctgcaa ttttatttcc atatcctacc ccttgatgta
    30841 tataatcaat ttgtgcgcca cttgctcgat aaaacggctg gagtggttga tttatctttt
    30901 taaataagtc aaagtaatcc tgtctggtcc ttaatagtgg tactggatgt ttcattgtat
    30961 tttctcctct ttttactacc aaatagctaa ttccgactgt tctaatcgaa gtaagccttc
    31021 aataaaaaaa taatcagaat agatcagtgg cacattataa gtcagttctc tatggtatgc
    31081 ttctgctccg cctccaatga tcccatcttc atccatattc caatttgcat agtgcttttc
    31141 tgtcttttgg agtatattga tagcagcttc atgatacatt tttgatcgta cagaggaaac
    31201 atatcctgct aattccagaa gaccgcatgc agcgcatact ccagcactgg tatcaatatt
    31261 cgaatctttt acagcaaaat caatgagagg aatataacca gttttttcga ttttctgaat
    31321 aaaatttact gctatctttt ctgctatagc tagatagtac ggattttttg tgtaacgata
    31381 acttaacgcg aatccatata aagcccatgc atttcctctg ctccaacaag aattctcatt
    31441 gtatccttgc ccgccaagta accgaatata tttccctgat tctgcatcaa attctgcgat
    31501 atgcccggtt gatccatctt tcctcactag atacttagct gttgtatctg catgctgccg
    31561 agcaatttta gagaacctcg gatcaccagt ttccctcgaa gcccaataca gtaatggtaa
    31621 attcatcata ctatcaataa tcatccaacc aggtttatgg tcattccatg ctactaaata
    31681 gttccctgaa atattatagc gtccagcaag taccgtagct gcatgtaacc ctagttgtcg
    31741 actatgtttg ttttgagact gttgataatg tgcaatagcc gatggtaaga ataaaaaacc
    31801 tacatcatga tgaacgtctg aaaaatggta cagggcagat tctaataatt gttcttgttg
    31861 tattgctgcc tctttgaact tttctcgttt tgtcttgtga aagagctgcc ataaaatacc
    31921 actccaaaaa ccattggtcc accagtcgat tcctctgtcc tttattacgt ctgtatattt
    31981 tccgttgtaa gaaatatatg gaattttatt ccccattctg tctaattccg catctatctt
    32041 ttcagaagct acattcaaaa tttttcttga ccattccttc gtctgttcat tcatggatat
    32101 cccgccattc ttttaatttt tatgaatgtg gagttgctcc tagaacgaac tagatggtta
    32161 acattcgtta ttttttttac ttatttgcag ctccaatgtc attctcctta aatttagact
    32221 gcgcccacac ataaatcaag accattggga tcactgaagt tgctaaaatt agcataattg
    32281 cgccataatt aattggctca cctgtactag aaaccgtcat atttttgata attaagggaa
    32341 ccgtatattt atctttatct gaaagcatga ctaatggaaa tagatattga ttccaacttc
    32401 ccataaagat aagtaaacca ctagtaataa tcgtaggtga taaaatcggt acagcgattt
    32461 tcgtaaaaat cacccactca ttggcaccat cgattctggc agcctccatc agtgctgtag
    32521 gaaattgact gctatattgt cgcatcataa acactgaagt tgtactggca atcgaaggga
    32581 tgatcacacc tgcataagta ttcgataatc ctaaacgact cataatgtaa aataaaggaa
    32641 tcaatgtggt aaaaaaaggc accatcctag atagcataac tgtattgaac aacagtttat
    32701 tccccataaa acgatacttt gctaatgcat aacccgccat tgtagaactg gctgtagcta
    32761 aaactgtact gattacagca ataacaatcg aattccaaat aatcaaggga taattatatc
    32821 tcgccatgat ggcttgccag ttttttaata gcatatcccc aaacttgaaa ttgattccgc
    32881 cacttaaaat ttcttgatta ctttgcgttg aagctacaat catatataaa tatggcatca
    32941 aaaatattaa ggcaccaaac acaataatga cgtacgtaaa aattctgctt tgtatctttt
    33001 gtttagtcat ttttatcacc tccgaattta aattgaatag ccgataatat aacagataca
    33061 aacaccatcg tccaggcaat agcagaggct tttccaaaat caaccatttc aaaacttgtt
    33121 ttatataaat tgactcctac gaccaaagct gaattttctg gtccattgga agtcccaaag
    33181 aatatatttg ggatattgaa attacccaag ccattgatag tggctaaaac tgtggccatt
    33241 aaaatgattg gctttagcat ggggatcgtt aataaaaaga attgccgaaa tttcgatgct
    33301 ccatctattt cagcactttc gtatatctct ttagaaatcc cttgaagacc agctaaaaat
    33361 aaaatagtgt tatatcctac actaagccaa atcatcgtga tgatcattga tattcgtatc
    33421 caaaaaggat ttgttaacca ctgtacaccg ttaattccta gcgcattcaa aaatccattg
    33481 aataacccag tcggattgaa aaaagtcatg aatacggaag ctacagccac cgttgatgta
    33541 atggttggaa tataatagac agttctaaaa aatccttttc cttttaactg tgctgaattc
    33601 aataaaacag caaagtaaat agctaatagc atcgttattg gaattgatcc tgccatgata
    33661 atcaaaacat tcgtgtaaga tttaataaac aatggatctc ggaagatagc tagataattg
    33721 tcaaatccaa caaattcaaa tgagtagcca attttcataa aactaaaagc aaacgagata
    33781 atgatgggaa tcaaaatcgt cacaataaag aaaataacaa aaggtgtgac caatccataa
    33841 gcactttttt tatgagacgt atctgttgct tttttcttgc tgttctttat tgtcttgctt
    33901 ggtaacgaag attgcatcat cgttaagtcc tcctaatatt ttttaatcac cagttaattt
    33961 tacgccgtac ttatgagcaa aattttctgc ttcttttaga tatgaatttt caaaatcacc
    34021 tgtttgccaa tagttatatg cagcggtagt caaataagac gtagcatctg aataagtggc
    34081 tggtaaaaca gtatttgatg tattttcatt gattttattc aatagttcat agtatttttg
    34141 tcctccttag tagtcaaact ttttctcagc tgcttctgtt tgataggcca atgagttaga
    34201 tgtagccacg cccagctcca gtgcgttggc taagcattct tcatctgtca gcataaatgt
    34261 aagaaattgt tgtgccactt gtggattttt tgcatcttta gggacataaa aacttgatcc
    34321 tcctgatact gcaccttttc ctggattttc ttttgaaaaa ggaatcagtg gagccatgcg
    34381 ccatttgtca gatgcatcag gaaaattcaa agacatattc gtagcatacc agccgccagc
    34441 aacaaacatt gcagattctt gaaatgcttt ctcagcatct tgtgcaccgt agaaatgtac
    34501 aatatctgag tcgatcattt ctttgattaa ctttgcagca tgtttcgctt ctttagtatt
    34561 cagacggata tttccttctt catcaagcaa agattgattc tgctgggcta gcatgttgat
    34621 aaacaattct tggtccccag attctggcaa ggcaattcca aaactaccag ttttttcttt
    34681 taatgctttt gccacctgga tatattcttc ccaagaactg atttcttcaa aatctacacc
    34741 tatttcagca aatttttttg gttgataata acaaagtgct ggggtaaaat cactagccca
    34801 aggaataatc gtttcattac tcgtttgttg acgcaaaata ttcaattttt gatcataaaa
    34861 ctgatcgcca tatttgtcat aaaatccata ttcatcagca ctataaaaag catcttgaaa
    34921 tttttccagc acacctgctg ctgaagtgtc tgccatggag ataatatccg gcatatcttc
    34981 gtgtgttacc aattttgggg tgatcatttg tactgttgct gttcccgaag ctacattcac
    35041 aatttttaag tcaatatttg ctccagtttt gcggttatag atttttgcag cattttcaac
    35101 atagtttgtc agtttgccgt ttgcgacata tacttctaat gtagtggctt tttttatcat
    35161 tggatctgcg atgtttgctg ttacttcttc gttagttttt ccacatgcac ttaagctgaa
    35221 taatagggta atgtttagca aagctatcac caatttgtat ctttttttca tgtctatccc
    35281 ttctttcttt tcaagttctt atataaaacg ctttcactta tgtatattaa cggaattagt
    35341 aacacaaata tttatataaa aaaatatttt acttgtcgtt ttggcttttc atttttgtta
    35401 taatagtcat taattataaa tagaaagctt tttatataaa aagagaaagg aaagtggttc
    35461 ttttgttaac aaacaaccaa tcctccaatc ttgtcaaaaa aacactaacc tattccatag
    35521 atacccatct tcatttatct gctgctccct attttcgact actaataaat gaaagcgcta
    35581 atttatatgc tgaatttgca cataaatcta tagaactaga taatccttcc cttttattca
    35641 ttgataaaca gcaagaagtc caaatctttt ctactcaaaa ggaaacacaa acttttatca
    35701 ttatccagtt ttattttgat gagcaattat tagcacatat tacgggacaa tctttttcta
    35761 tagatcaaga aataacatct atcattactt ttctgaaaaa tgaacagttc aaaattgatt
    35821 atctaaaaca tagtaagcca gctatttcct atgatcagga aatcaattct tttttcatac
    35881 tatgccaaca gatgagcatt catttgcttt ccttattagt tacttattgt ctgcaaaaaa
    35941 ttcaattgtc ttccttacca aggcattatc aacaggaact tgctttattg acaatacctt
    36001 caaatgagaa agtcattcct aaaaaaaagc atattcttta ttcagatgaa ttagttgatc
    36061 caatcatacg atatttagaa gaacatcttt cagaaaattt tttgcttgaa caattagccc
    36121 aaattttttt tatcagtcca gccagcttaa aaaaacattt tagaaaagtg aatggaaaaa
    36181 gtgttattag ctattttaaa gaactaaaaa tggaaaaagc aaaacgtctc gtgctagaaa
    36241 atgaattaac ctatacagaa attgcagata tattaggatt tcattcgatc catcattttt
    36301 cttcagcttt taaaaaatat acagggttat ccccttcaaa gtattatcta tccttaaaat
    36361 agaaaaaaat ttttaggttt tatccacaaa ttatttctct atattttctg tctattcaaa
    36421 ataaacaata attttccggc acaattattt gctgtttttt accataacat agtacgatca
    36481 acgtagaaaa ggagatgttt ttatgaaagt tgttgtcatt ggcggtgtag ctggcggtcc
    36541 ttcatttgcc actcgtttcc gtcgattgaa tgaagcgcac gaaatcatta tctatgaacg
    36601 cggagaaaat atttcttatg caagttgtgc tttgccttat tatttaggag gtgtgatcac
    36661 tgaccgtgac tcgctgatcg aacgtacacc agaaatattg aaaacaaaaa acaacatcga
    36721 tgtctttact aaacacgaag taacagcaat cgatccttct actaagcgat taacagttaa
    36781 agacctatcc acaaatgaag aaataaaaac agattacgat aagttgatca tctcttctgg
    36841 tgctagacca gattatccgg atattcccgg agtttttgaa gcagaaaacg gctttgtcct
    36901 ccgtagtgtg acggatgcgg atcgaatcaa atcgttcctt gaagaaaaaa atccacaaca
    36961 tgtcgtcatt cttggtgcag gtgttatggg tctggaatta gctgagaatt tcaagcatcg
    37021 cggcttagac gtgactttaa tcgatcaatt gccacaagtc gctttccctt atgatccaga
    37081 aattgctaat ttagtttatg acaaattgct gaaagaagga ttagccgttc atttagaaac
    37141 aagagttact gagatccgtg ataaaggtcg agaaatagta ttatcagatg gctccgtcct
    37201 ttctgctgat atgctaattt ttgctgttgg tgtttctccg aagaatgaag tggtgaaagc
    37261 aaccggcata caattatcag atacaggtca gatcattgtt gatgaccagt tacaaaccaa
    37321 tctgccggac atctatgcga ttggcgatat tatcgaaacg actagtgtag tgactggtca
    37381 gccgatccaa agtatgcttt ccagtgcggc caatcgtcaa ggacatatgc tggcagatat
    37441 tttaaatggt acgcctatgc gctatcgcgg atatattggt gcaggtgtcg caaaaatctt
    37501 tgatcataca gcaagttatg cgggaatgac agaacatgaa ttaaaagcat caggcataac
    37561 aaattataaa actgttttta tcactccctt tgaccatgcc tatttctatc cagaagctac
    37621 aagattaaat ctaaagctga tttttgatgc agatagcggt cgtattttag gtggacaagc
    37681 atttggagaa aaaggtgtcg ataaacggat gggagaactt tctgtagcaa tcaccggaaa
    37741 cttgacagtc tttgatttgc ctgatttgga gttgccttac tctccaccgt attctactac
    37801 ccgtgacccg ttgaatatag ctggttatgt cgcaatcaat caaatgacga atatcgtaga
    37861 aacgatcaaa gcaagtgata tacccgaaaa cgatttgaaa gaagcgttct ttttagatat
    37921 acgtgaacct aataaagcac cttctggcag tatctcggca acaaaaaata ttccaatgaa
    37981 tgagttacga gatcgaatca atgaaatccc aaaagataaa aaagtttaca ttactttcag
    38041 aagaggattg aatacttata cttctgcccg aatcttggca ggtttgggta tcaaagcgat
    38101 tttgattgaa gaataaaaaa acgaccgcgg tgggtagccg cggtctagga gttattttta
    38161 cttgaggagt aaaaatgaaa aagtatatag ggttgttggt tggtatgtat atagaataga
    38221 agataaatgt gaagaaattg tgcattattt cttcacattt attaggttat agtttaagaa
    38281 agtttaaaca ttgcgcaatt taattatttt agctgtttct tttcataaaa aaacatgttg
    38341 tgactctgag acaaatcata gtccatagtg atgtctctag agtaactacg cctaatatta
    38401 cgaggcatca tattaatcta tcagcactag tacctaaact agcatccctt tcgaatattt
    38461 tttcttatat aataaagttt gctttcactc ctctaatctc accaaatcga ctggcttgcg
    38521 ttgtgtgata ctaggaactg attggtttag aacgactttt ctattgtaat catatttttc
    38581 gccatcctcg ttgtcttcta atccttcaat gaatgatccc taatgtgtgt attaaataat
    38641 ttaatttttt tgttcctatt tatttaa
//
LOCUS       DADGHT010000014        37758 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.014, whole genome shotgun sequence.
ACCESSION   DADGHT010000014 DADGHT010000000
VERSION     DADGHT010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.014"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(87..431)
                     /locus_tag="JX887_000645"
     CDS             complement(87..431)
                     /locus_tag="JX887_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAX1256655.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(568..1704)
                     /locus_tag="JX887_000646"
     CDS             complement(568..1704)
                     /locus_tag="JX887_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAX1256656.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(1893..2867)
                     /locus_tag="JX887_000647"
     CDS             complement(1893..2867)
                     /locus_tag="JX887_000647"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAX1256657.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(2947..3822)
                     /locus_tag="JX887_000648"
     CDS             complement(2947..3822)
                     /locus_tag="JX887_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAX1256658.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            3952..5859
                     /locus_tag="JX887_000649"
     CDS             3952..5859
                     /locus_tag="JX887_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAX1256659.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(6400..9678)
                     /locus_tag="JX887_000650"
     CDS             complement(6400..9678)
                     /locus_tag="JX887_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAX1256660.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(9949..10494)
                     /locus_tag="JX887_000651"
     CDS             complement(9949..10494)
                     /locus_tag="JX887_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAX1256661.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(10506..11198)
                     /locus_tag="JX887_000652"
     CDS             complement(10506..11198)
                     /locus_tag="JX887_000652"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAX1256662.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(11217..11501)
                     /locus_tag="JX887_000653"
     CDS             complement(11217..11501)
                     /locus_tag="JX887_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256663.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(11514..12077)
                     /locus_tag="JX887_000654"
     CDS             complement(11514..12077)
                     /locus_tag="JX887_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAX1256664.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            12305..12967
                     /locus_tag="JX887_000655"
     CDS             12305..12967
                     /locus_tag="JX887_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAX1256665.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            13091..14287
                     /locus_tag="JX887_000656"
     CDS             13091..14287
                     /locus_tag="JX887_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAX1256666.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(14388..15764)
                     /locus_tag="JX887_000657"
     CDS             complement(14388..15764)
                     /locus_tag="JX887_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1256667.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(15801..16667)
                     /locus_tag="JX887_000658"
     CDS             complement(15801..16667)
                     /locus_tag="JX887_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAX1256668.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(16756..17781)
                     /locus_tag="JX887_000659"
     CDS             complement(16756..17781)
                     /locus_tag="JX887_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1256669.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(17799..18473)
                     /locus_tag="JX887_000660"
     CDS             complement(17799..18473)
                     /locus_tag="JX887_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1256670.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(18657..19550)
                     /locus_tag="JX887_000661"
     CDS             complement(18657..19550)
                     /locus_tag="JX887_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAX1256671.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(19624..21321)
                     /locus_tag="JX887_000662"
     CDS             complement(19624..21321)
                     /locus_tag="JX887_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAX1256672.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(21314..22627)
                     /locus_tag="JX887_000663"
     CDS             complement(21314..22627)
                     /locus_tag="JX887_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAX1256673.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(22627..26664)
                     /locus_tag="JX887_000664"
     CDS             complement(22627..26664)
                     /locus_tag="JX887_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAX1256674.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(26677..27135)
                     /locus_tag="JX887_000665"
     CDS             complement(26677..27135)
                     /locus_tag="JX887_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1256675.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(27433..27951)
                     /locus_tag="JX887_000666"
     CDS             complement(27433..27951)
                     /locus_tag="JX887_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAX1256676.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(27953..28570)
                     /locus_tag="JX887_000667"
     CDS             complement(27953..28570)
                     /locus_tag="JX887_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAX1256677.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(28567..29421)
                     /locus_tag="JX887_000668"
     CDS             complement(28567..29421)
                     /locus_tag="JX887_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1256678.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(29418..30329)
                     /locus_tag="JX887_000669"
     CDS             complement(29418..30329)
                     /locus_tag="JX887_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1256679.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(30370..31704)
                     /locus_tag="JX887_000670"
     CDS             complement(30370..31704)
                     /locus_tag="JX887_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1256680.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            31912..32742
                     /locus_tag="JX887_000671"
     CDS             31912..32742
                     /locus_tag="JX887_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAX1256681.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(32986..33235)
                     /locus_tag="JX887_000672"
                     /pseudo
     CDS             complement(32986..33235)
                     /locus_tag="JX887_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(33426..33620)
                     /locus_tag="JX887_000673"
     CDS             complement(33426..33620)
                     /locus_tag="JX887_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256682.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(34125..34310)
                     /locus_tag="JX887_000674"
     CDS             complement(34125..34310)
                     /locus_tag="JX887_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256683.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(35160..35501)
                     /locus_tag="JX887_000675"
     CDS             complement(35160..35501)
                     /locus_tag="JX887_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAX1256684.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(35501..35731)
                     /locus_tag="JX887_000676"
     CDS             complement(35501..35731)
                     /locus_tag="JX887_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAX1256685.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            36018..36356
                     /locus_tag="JX887_000677"
     CDS             36018..36356
                     /locus_tag="JX887_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256686.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(36561..36800)
                     /locus_tag="JX887_000678"
     CDS             complement(36561..36800)
                     /locus_tag="JX887_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAX1256687.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(36776..37123)
                     /locus_tag="JX887_000679"
     CDS             complement(36776..37123)
                     /locus_tag="JX887_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAX1256688.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
BASE COUNT        11053 a         8020 c         6575 g        12110 t
ORIGIN      
        1 aagacaacta atttgcgtcg tccttacaaa gttagtcatc taacaatagg ccgtttcaaa
       61 actagttgtc tttttatatc cacagatcat tcgacttttt cgaataaccc acggctaatc
      121 atcccatcca tcagaaaata aaatttatct tggctcattt tctgttttgg atctttgaaa
      181 atattgactg ctttcaatcc atttgctgta gtgatcgaca ttttcaatgt ttgaatatct
      241 tttgatacag tgatttttaa tttgaatcct tctttgcttt gcggcgtggc atctaatggt
      301 cggatcaatt gataattgcc tccgtttgtt tctgtaaatc cattatcgcg caatgtatat
      361 ctttttgcat caggatgcaa acgatagcta attggtgcgc ccagtaccgt tgctgttgtt
      421 tcaaatgcca tgattttcac ctcgataaaa ttagtttctc tttattataa aagtttatcc
      481 tgatttttac taggtttttc agttaagttc cctaaaaaat gaaggcgttc tctcagacat
      541 ctgttcatat aagaatgact tcactagtta ttttttgaca gcacgaacta attgatcaag
      601 gaaatactgg atgtcgtctt cggtatttcc caaaccaaag ctgatacgga tggattcttt
      661 tagtatcggt gtatcttctc catacattgc ttctaatacg tgtgaaggct cgatatttcc
      721 tgctgtacaa gctgaaccag tagaaatagc gaccccatta agatcaagct tcatcagtag
      781 caaatcattt gcttcgccaa ttaagcgaag attcaacaca tgagggagtt tattcgttaa
      841 atcaccattt acttgataag ggatttcgtt tgcttctaat gtatcaagaa tcaattgctg
      901 gaatccttta tatttgttgt tacgtgcttc acgttcttca ggtgacagca gttcaactgc
      961 ttttgccata ccccagatcc ctgctaaatt ttctgtacct gcacgccgct tttcttcctg
     1021 ctccccgcct aaaagcaatg cagggatatt tactccgtct cgtttatata agaaaccgac
     1081 gccttttggc ccattgattt tatgagcaga gatacttaat aaatcgattc ctaattcttc
     1141 tggatggatc gtttggtttc cgtacgcttg taccgcatct gtatggaaat aagctggatg
     1201 atccgctaaa agttcaccga tttctttgat tggcatcaaa tttccgattt cattgttccc
     1261 gtacatcaca gagaccaaga tcgtatcttc tcgtaacgct tttttgacct cttcgatcga
     1321 cagattccct ttttcatcta caggcagata tgtaacgtca aacccctttg tctctaaata
     1381 tttcatggta ttaagaacag caggatgttc gatagctgta gtgattagat gtctgccttc
     1441 tttttgacgc gagaacgctg tttctaagat agctgtatta tccccttctg ttcccccact
     1501 gttaaagatg atctcgtgag gttttgcttg cagactgtct gcaatgattt gtcttgctgt
     1561 ttccaatttt tcatgcgcgt ggcgaccaaa tccatgtatg cttgaaggat ttccaaacgt
     1621 gtcttgcatg attgccgtca tcgcttcaat tacttgtgga tgcatggggg tagttgccgc
     1681 atgatccaga taaatagttt tcacttcatt catcccttcc aaattattgc taggcacatt
     1741 ctagcataaa atagcgaaca aaccaaagaa gagctcattt ttgtctagag gacgtttcat
     1801 gggcatagaa aaaaggagct gtgacaaaag tcttgtcgca gctccttgaa gctgctcact
     1861 tctgtcacaa cttctttccc tctttttttt gtttattcga attctttttc ttccagacgg
     1921 aataacggac tcatcggtgt attttcatgg atgcgtttga ccgcttcacc cattaattct
     1981 gaacatgtaa cgattgttaa gttttctgga tgacgatttt cttctgtgaa aacagaatca
     2041 gtgatacaaa tatctttgat tggtgcattg tctaaaatac ttttcgcatg atcggacaat
     2101 aatccatgtg acgcacaggc atatacttct tttgcgccgt tttcttttaa tacatttgct
     2161 gctcgtgcaa gcgttgctcc tgtgttcaag atatcatcta ccatgataca tgtctttcct
     2221 tgaacatcac cgatcacata accaccctca gttgaagcat catctgcatg atctacgatg
     2281 gctaatgtgc tgttcaaata ttctgaaaga ctacgtgcac gctgaacacc gctgtttttt
     2341 ggcgaaacaa ctacgatgtc atctcccgtc agacctaatt gacggtaata atgagcaaac
     2401 aacggcatcg taaataaatt atctacagga atatcaaaga atccttgtac ttgaaccgtg
     2461 tgcagatcta aagtcagtac tcgagttgcc cctgcttctt cgatcaagtt agcgatcaat
     2521 ttcgcagtga tcggttcatg aggtttcgcc gtgcggtctt gcctagcata cccatagtaa
     2581 ggcaatacga cattgatcgt tttcgcactt gctcgcttca ttgcatcgat catgatcagt
     2641 agttccatat agtaatcatt gacaggtgca ttcgttgatt gaacgatata cacatgatcc
     2701 cctcgaatac tttcttcgat attgatggaa atctcgccat cactaaattg cttcacgacg
     2761 cttttaccta attctgttcc gaacactttc gcgatttttt cagctaatgg acggttgcca
     2821 ttcaaactaa aaatcttcaa cgtgtcatcc tgatacttat tactcatgta gtcctcccca
     2881 aaacttctct attcttcgat agtttaacat atttttccaa gattttctgt taatttcagc
     2941 aaattcttaa ggaagtgaaa ctgttccgtt actccaactg gcaggaatga ctttatgata
     3001 atcgccccag ttgtcgtgta ctttgtaata acgttctcct gtttcagttt caaaataagc
     3061 gtacgctgtc acccaatgat tgccatatgt actgccaagt actttcaaaa taccaatcat
     3121 cacaggtttg ccttcacgta tacgttttgt agctcgctgc catgaaccta gaagagttgc
     3181 tcgtgcacgc tcatgattgc cattcttctt taaaaaacta gaaatccctg tactaacctg
     3241 aaaaggaatc gtaggaagtc ctagtggttg gatctggcta cgcaatgcct tcgtcaaaac
     3301 caacgaatca gccgtatttt tcttgcgaat ctcatttgga agcatccacc ccttacgata
     3361 gtcttgataa taggcaagga gaactgctgc cgcgtaagta ccacaaagat agcctgaggg
     3421 ggtagcccat ttcttatacc tcaaaaaacg ttcttctggc aatcccaccc agcaatttgc
     3481 gagttccttt cctgaccttt tttcttcgat caaaacggga atatcttctt ttctgttgat
     3541 ccatctagat aactcgattg gctcttcatt gatcagcttc cattttttac aagaaagacc
     3601 ctcttgataa gtatattttg ctggagaata ttctaccgga tgtcctgatt gatcgataat
     3661 cacataactt tgatcttcaa aaaccagagc taaaaaaagc aatttacttt ttcttgactg
     3721 cagctgctga gtgctggcta attttttaat ttttttatct actttgaaat ataaaggttt
     3781 atccactact tgattcagtt gggatcgcct cctttttttc attataagtg aaggattgaa
     3841 aaaaacaaat cagtttgatt gttcgaattt tcaatttttt atgttctatt tgttaattcc
     3901 ttcattttgt aagataatgg gcacacgaaa caaaaaagga gcgatcgatg aatgaacaaa
     3961 gaacgattga aacaagattt ctatgaagca gtcaatgaag aatggcaaaa aacagcaaaa
     4021 atccctgcag ataaaccagc tacaggcggt ttccaagatt tagttgacgg gatcgaccaa
     4081 cttttgatgg gagaaacaga cgatctgctt gcccatccag aaaaagtgtc ttcagaaaaa
     4141 atgaaacatt tccttgcata ttatcaactg gcaaacgatt atgaccgaag aaatgagttg
     4201 catgctcaac cgcttcaacc tataatcgaa aaagttgaat cattgcagtc tttcgacgaa
     4261 ttgaataagc aatttccaga atggctgttg gatacattac cattgccatt taatctggat
     4321 gtagatgcag atatgaagaa tgcgcaaacg aacgccttct ttgcttatcc gccttcttta
     4381 ttccttccag ataagacgta ttatgcatca gaccatccca acggtgcaca actaataggc
     4441 gttttctttg atatggctgt tcagttatta gagcttgccg gcaaagaaaa aagtcaggca
     4501 gaagcaatca cggaacaagc agtgcaattt gataaattga ttgctcctca tgtaaaaagt
     4561 gcagaagaaa acgcagatta cagcaaaatg tataatccgc aatcttttga tacatttatt
     4621 aaatacacag ataaactgga cttgaaaaaa cttgtcacgg gtttgattgg gacaactcca
     4681 gataaagtga tcgtaactga tccagtgtac ttcgatcatt tgaatgacat cctgacagaa
     4741 gctcattttc cgttattcaa aagctggatg atcattaaaa cagtacgttc tcttagtggt
     4801 tatctatcag aagaattccg ccaagtcagc ggaatctatt ctcgcgtatt gtctggaaca
     4861 gacgaagcaa tgcctcagaa aaaagcagcg tattaccttg cctctggaca attcgatcaa
     4921 gtagttggcg attactacgg aaaaaaatat tttggcgaag ctgctaaaaa agacgtagaa
     4981 caaatggtga aaaaaatgat cgccgtttat aaaaaacgtc tagaagaaaa tgactggctt
     5041 ggggatgcaa caaaagaaaa agccgtcata aaattaaata acttaggtat ccaagtaggc
     5101 taccccgata agatcccagc attattcgac cagttcaaaa cagtacctgc agatcagggt
     5161 ggtactttgc tttcaaatac tcttgttttc agcaaactca cattaaaaga tcgtttcagc
     5221 aaatggaaca aaccagtgga tcgttcagaa tgggaaatga gtgctgacac ggtcaatgct
     5281 tattatcatc catttcggaa tgtgatcgtc tttccggcag cgatccttca agcaccattt
     5341 tacagtctag aacaatcaag ctctgctaat tatggtggaa tcggagctgt tatcgctcat
     5401 gagatttccc atgcatttga taataacggc gctttatttg acgaatatgg caacttgaac
     5461 aactggtgga cagaagaaga tcttacacaa tttcaaaaca aagcacaagc aatgatcgaa
     5521 gaattcgatg gtctgccttt tgctgacgga aaagtaaacg gaaaattaac cgtttcggaa
     5581 aatattgctg atgcaggcgg tctaagctgt gcattggaag cagcaaaaac ggaatcagat
     5641 ctttctatcg aggaattctt tgtcaattgg gcaacgattt ggcgtacaaa agcaaaaaaa
     5701 gaataccaac aacttttact gcaaatcgat gtccatgccc ctgctaaact ccgagcaaac
     5761 gtgcaaccaa aaaaccttga cgaattctat gaaacatttg gtatcacgga acaagacgct
     5821 atgtatctag cgccagaaaa aagagtgcga atctggtaag aggttgtgcc agaagtggtc
     5881 agcttcaaga aataagaagg aatttgggaa aatcgcttct caaatttttg tgacatttcg
     5941 gcttattttt cgaagaagtt acttctggaa taccatgtat tagaggttgt gaaaaagctg
     6001 cttagtttca agtagtaaga aaaattttgt gaaaatggct ttccacattt ttgcataaat
     6061 ttgacttact accgagaaac tggcttttga acaccgttta tcgagaggtt gtgaaatcag
     6121 cgtcctgacc tgagtattag agaaaaaaac ggaaaaatag ttcctcatat tttgccgttt
     6181 gttgagctaa taccgagggt cagctgattg aacaccgttt agtggagaga ttgtgaaaaa
     6241 gctgtcctgc atcaagtaat aagaacagcc aatcaaaagc agcaaggaga acctcatcta
     6301 taaaaagata gaaggaagtg agacatctat tggtctcatt tccttctatt tttactttcc
     6361 tcagtcaatt gttttacatc ataaaaggag aaattccact tatttttttc gctgtttcat
     6421 gacataaaca actacaccga ttaacaaaat tcctccagct aatgctagca acgggttatt
     6481 aaattctccc gtttttggga gtccttgagt gccatttttt tcactttctt ttgctgtcct
     6541 atccggatga gaaggttttc catttggttt tccatttggt gattcatttc ctggattttc
     6601 tctttctggt ttgtcatttc ccgggggcac atcggcagtt tctcgcacag tgatcgcttt
     6661 ttgctgggta acagattctg tatgagcaga ccatttttcc ccatcaaata tttccgaacg
     6721 ataagtgact tctagcgtat attctccttt tgaaggtgct gaaaaaatag cggtatgatt
     6781 agaaaattga gcacttgact gtgtttcaac gatttggatc ttttctggga aataacgcat
     6841 atcttcaaag acaggcgttc cttgatttgg tgtgaaagtt gacacaaaaa ctgtaaaagg
     6901 cttcagttca atgatatttc cttctgcatt ctccgccaca ccatttgctt cttgtataat
     6961 aatcggatta ttttgttcat ttggttttgt ctgatttggt tcttgtacga ttgcatactc
     7021 tggatattcc gaagacggtg aggtttctcc gtcaaaaata gcacctacag ataatggaag
     7081 accatccact ctttcctttt ctgtttgacg attccccggt ttaatctgca tcagtccatg
     7141 aacatggata cttccatttt catagcgcgt aacaggctgc tgaccttctt tcgaacatgt
     7201 atttagagac tcgatccaat cttttgatat ggtatgtcca agagtatttt ctgattgttt
     7261 ctctcgttca ttccaatagt agttcaacga gtggtagatt tgatcttcgt tttgattcaa
     7321 tgggcggatc tgctctctca tctcaagatt ctctgttcgg aaagataaga taccagaagc
     7381 atggtagtct gtgtttcctg ctgaagaggt ataaagagcc acattatatg aaccgttatt
     7441 aaaacttgta ctgctattga cgataatatc tgttccgcta ttggaatcga ttcctttcgc
     7501 aagattttcg aaagacaaac tattgatcaa ttcatgaggg cccgttaaag aagaaccgcc
     7561 cattttgaat ccattaccgt taccttctcc ctcaattcct ggtacccagc cgtttcgata
     7621 agcaactgag tttttgatga ttacttttcc gatcgaacct gtttcatttt tagcaaaaag
     7681 gtcccaaccg tcatctgcat tatgatacgc gatacaaccg tcaaatacat ttccttctcc
     7741 tattgtcagt ttggccgcaa atccatcggc atcttcaaat cctggatcgg cattttcaaa
     7801 agatgtacag ttcttgacta agttatgcgc gggccatgct tcgaaaggat catttgagct
     7861 accgctgatt tggattcctg tatttccatt ccgataagca tgaatctctt cgatcaaatt
     7921 atgatttcca gaaatctgta atcctttttg catagctgca ctatttgtaa tgtcaaaccc
     7981 tcgtaaaccc cagtagtgac tgaacagtgt catcccattt ccagttcctt taaaatcaag
     8041 tacaggacgc ttgttttctg gatttttctc tgcaatcaac tgaatcgggt tttctcttgt
     8101 cccgttaacg ccttttggaa tcgtcaatcc tctttcgaag gaataagttc caggcgccat
     8161 gacgattgtc tgcccagcat atgcgtatct caatgcttgt gtcagagata atggattttg
     8221 tctgcttccg tttcctgcat ctgacccttc tggtgttaca taaactgtcg aatatttagg
     8281 tttacggtag tccactgtat gaagaatctc ttttgtttca taactagtca tctctacgta
     8341 ttcttctggc ggatagtttt tatctggcgt aaaactgaaa gtaaattcgt tcgttccttc
     8401 catcagtttt gtctgataat caaattcccg attcgcagtg atagccaagt tttttgcgtt
     8461 cttaagcacc tctcctgttg ctttattttt aattgtcaat aatccgtcag catttgctct
     8521 aaaggacata gtatgatctt ggtttcctga atgattacta gaggtcacag tgtaaatcgg
     8581 atcaatcaag cgagtaggtc tttcttgccc aggaggatct gtcgcaggat ctgagtaagc
     8641 aacttcgatt ccttctacct tgatcgtcat attccttgct gcagcaaatc ctgcataaat
     8701 aaccgattca tctgaagcgt ataatttttc ccagtcatac atgatgtcag aagccatttc
     8761 ttctcctgtt tcaggatcgt aataatatgc ctctaaacca gtattcgttt ttttcatctc
     8821 tacgtccagt ttagtaatcg agttcgtggc cggaaacaga ttcccatgac cgtttccgaa
     8881 tatattataa gaacctgttt ctttttccaa gaaccctgct gaagtctcta aaggtgttgt
     8941 ttccactgag acactcccag gagctggcgc agcttgcgga tcttcagatg atattcctgt
     9001 gattgcccgt gtccccaatc caagtcgcat cgtatatttg ctgccgctcg tgttgaccac
     9061 ttcttgtcta tccgagtccc agacatattc gatccgactg cctagtatgg caaatgaatt
     9121 tgaataaaat gcctgcccaa acaaatgatt ttttggtact gcgtctctta ccattaaagc
     9181 aaatccttct tgggcattcg tataggtcca agattctatt tcgatcgtcg cccgcatcct
     9241 aaagttgatg tctttgggga ttgcttgata ataataggtc attccatctg atccgcttga
     9301 ctggaatttt ccgccgttat tcgtggaaga gagccgcacg ccgtcttcta atggttcaat
     9361 ggcataccta ctagcacttg tgctttctcc gaaaacaacc cctttccact cttcatttgc
     9421 ttcttcagat tgcttttttg tcttttcatt ttctgattct ttcatcatag gatcatttcc
     9481 ttcttccgta tccatatctt cactagttct tggtatttcc tccattgttg acatcccttc
     9541 aatgttcacg tgtgcatttt cttcgttcac agactgttgt tcgttagcag caacttcaac
     9601 gacagaaatt aaaaccgggg tactgagcat aaggagattc atcattagcg cactgtattt
     9661 tatacgtttt tttaacaagt gtattcctcc cgtaacaaat tagaaagcgt ttacttaaag
     9721 tattacctaa tttattttta ctgtcaataa aaaacaaaat tataataagt gtattttata
     9781 aaaagaaaaa atataactta agttgttgat aataaagaga tttattaacg taaaaagaat
     9841 aagttttttt aaaataacgt ataaaaaaga gcataaaaca aagtcgtttg ttttatgctc
     9901 ttcttttatt attttgtgct ttttatttta tcaaatcact ttgttttttt ataaaatttc
     9961 tgcgcctagt gtggactcaa aatgtctcaa tgcccattca tgtccaacgg gatcgaaact
    10021 tgccacggaa tctttgaaaa tatggagttt gtatcctaga ttatacgcat cgactgctgt
    10081 atgcaacaca cagatatctg tacatacgcc ggtcaaataa atatctgtga tctggcgttc
    10141 tcgcaaacgg atgtctagat ctgttccact aaaagcggaa taatgccgtt tgtctatcca
    10201 ataaacattt tcctcttgct catagtcttg gtataaactt tttaaagagc cgtacaattc
    10261 ccgtccaccc gttcctatca cattatgcgg aggaaataag cggttctccg gatgaaagga
    10321 atcttttgga tcatgcgcat caatggcaaa aacgacaaaa tccttttgat caataaactt
    10381 ctttgtatga gcagtcagct ttttttcaat tacttgtcct gctgtcccag tagtcagctt
    10441 tccatcctct gcaacaaaat catatgtgta gtcaatcgag atcaatgcgt tcatcttagt
    10501 cctccttata cgagatgttt gacaaattcg atcaccattt ctgctgatcg tttgcctgcg
    10561 tcttcgataa attcgtcaaa gctttgtgtc gccgagtgat ctgctgtgtc gctcattgca
    10621 cgtacgatca aaaatgggat attgaactga cgagctgttt gtccaacagc ggctccttcc
    10681 atttcgcaag ctaatgcttc agggaaattc gttaagattt ctttgatttt atctggcgag
    10741 tcgacaaatg tatcacctgt aacgatcaat ccttcttttg cgttcaaatt cgttgctttt
    10801 gctgctttaa ccatttcact gcgcaaatat gtgcttgctt cataatatag aggcattcct
    10861 ggtaattgtc ctgggttgta gccaaatcct gttgcatctg catcaaaata agctactttg
    10921 tctgatataa cgatgtcacc tacttgtaag ccttcaccga ttccgccagc tgaacctgta
    10981 ttgatcacca tgttcacgcc gtattgttgg atcaacagac ttgtggtaat agatgctaag
    11041 acttttccta taccggaacg tacgacgatc acttcgtggt tacctaatga acctgaaata
    11101 aataaagcgc ctgcgcgttc ccatgataat ggttcgctta ggttctctct caaaattttt
    11161 acttcttctt ccattgcgcc gataataccg attttcatct ttttaattcc ttctttctat
    11221 ataaatgcga ttgctaaaaa aaccacacat aacattagga taacaataat aagagatttc
    11281 atcaaaaaag agttccattt ggtcgtcttt tcccgttcgc tgatccttgt tttcgtgatt
    11341 ggtttattct ttttgctttc tttacgataa aagctggcaa tctttttttc ttcttgctga
    11401 taagctgttt ctgcttttcg ctgttttttt aatgactcgc ttgcttgtgc ttgttgtcgc
    11461 ttgcgaagtt cgcttcgcgt aataagcggt cctttggcca taagccgatc cctctacttt
    11521 cctttggtca atagttccca gtattgaatc gcataaatcg tctttgcatc acaaatcaac
    11581 tgatctttca tcgcttgttg cgcctcttca agagttagat gatacaactc cagtacttcg
    11641 tcttcatctt gtgctaaagg attctcgacc ttctctaccc cttgtgcatg ataaatatga
    11701 aggacttcat ttgcaaaacc tggtgaaaga tacatcgaag taagatggct cagcgacttc
    11761 gcacgatagc cagtttcttc ttctaattct ctagctgctg tcatttcggg attttgtcct
    11821 tctcctggat cgatttttcc agctggaatc tccaaaatca ctttttctaa aggttttcga
    11881 aattgtttga caagaagcag acgatcttgt tcgtcaaaag caatgatccc gacaccgcca
    11941 ggatgaaata ccagttctct cttcgaagtt cctccatctg gcaaacgaac ttcgtctaca
    12001 gcaacatcaa taatttttcc gctatagatt tctttgcgac tgattgtttt ttcttcaaat
    12061 tgctcattgt tcagcatatc ttctcctgct ttctttgtaa tcataactgc ttttttttca
    12121 tttttcaatt tttctcaaaa actccttatt agtttaccat agataaacct tagattttct
    12181 ctaaatatag aaaatccttc tttagtccga tactctttct agtagtccgt atgctaaaat
    12241 aagtatgtaa tcgaataacg aaaagaattc aatactcaac gataaatgac atggagggtt
    12301 tattatgata aaacgaaatt ggccgtggct tctagcattg gtcttgctat ttctctttgt
    12361 ccgaaacaat agtttttctt ttgttctagg acttttattg ataggtgtag ttttagtttt
    12421 gtggggactc tttggttcgc gcaggaaaaa gggaaaacaa gaagaaattc ctgcactgac
    12481 tgacgaactt gaaactcact atgaaaaaag cggtatgaca gcgaatgaaa tttcattttt
    12541 tcgacaaaca atgaatcaaa caaaaaatga gatcaatcaa ttgcaaatga atatgcagca
    12601 gacagccaaa cttaaagcaa tcgatctccg ccatgatcca gtcaaagcag cgaaagcttt
    12661 attcaaagaa ttggtgaaag aaccaaaccg actgcatgaa gcaagtcagt ttctttatac
    12721 gcatctgccg aatctagttg atttgacaaa taagtataat gagatcaatg accatgagat
    12781 caaaaacaaa cagacctatg aaaaactaga agaaagcgcg cagatcatcg accagctgtc
    12841 agctttaatc gcacaagatt atcaaaaatt cgttgctgag gatctagatg atatcgacgt
    12901 agagatatct gttgcgaaac agagcttaaa gcgtgataat aaatatgaac cagaacaaaa
    12961 ggattaactc ttttgttcat aaaagaagac tcggaacatt cagatgatgt ctggctgttt
    13021 cgagtacttt ttctaaagta gagacattca tgtaagaatc gagaacagat tcaacaagga
    13081 ggaatttttt atggatcata aaccgactga aacaaaagat gttacaccag ttaacgatac
    13141 acttgaagat ttattgaaca acccgttttc aactccaaca gatacgctga ccacttcaca
    13201 acaagcggag attgatcagc tccaagagca acagacagct gctcgtttaa ttgacaaact
    13261 accggcggaa cgccaagaac aagctaaaca gctagcagca aaaatcgatg ctaatgatgc
    13321 acagtctgtc atcagctacg gatcggctgc ccaagcaaaa ttaagtgaat tctcacaatc
    13381 gatgttgaat catgtgcaag cacaagatat tggtcctgta ggagattcct taactgaact
    13441 gatgtatcgt ctccaagaag ccaatcctga cgaactgcgt gccggagaag ggaacatctt
    13501 ccagcgtgtc ttcgggaagg tcaaacaatc gatctatgaa gtgacagcaa aatatcaaaa
    13561 gattggtgca caaattgaca agatttcagt gaaattagat aaagaaaaag acggtctgct
    13621 aaaagataat ctgatgttag aacagcttta ccagaaaaac aaagactact ttgatgcact
    13681 gaatatttat atcgctgctg gagaattgaa aatggaagaa cttcaaacaa cgatcattcc
    13741 agaagcgatg aaaagagcag aagaaactgg cgatcagatg gatgttcaga ttgccaatga
    13801 ttacacgcaa ttcctagatc gtctggataa acgtacgcat gatcttcgct tagctagaca
    13861 gatcacgatc cagcaagcac cacaaatccg tttgatccaa aacacaaatc aggccttggc
    13921 tgaaaagatc caagcatcta tcgctacagc cattccgctg tggaaaaacc aagtcgtgat
    13981 cgcattgacc ttgcttcgtc aaaaagatgc agtaactgct caacgccaag tctctgaaac
    14041 aacaaacgac ttattgaaga aaaattcaga aatgctgaaa atctcagcca tcgaaacagc
    14101 gaaagaaaat gaacgtggaa tcgtggatat cgagaccctt caaaccactc aaaatgattt
    14161 gatcgaaaca atccaagaga cattgcgtat ccaaaaagaa ggaaaagaaa aacgtcgtca
    14221 tgcagaagta gagcttggac acatggaaga agatctgaaa caaaaactgt tggatttaac
    14281 ccaatagatc acctttcgct tgttactaaa acaaacgccc aacaacagtt tattacaact
    14341 gttgatgggc gtttttctta tctttcttct aacttctcca ttggagtcta tttctcattc
    14401 atcttgctgt gtccatagcc atagccaaaa taaatgatca gtccaataac cattacgata
    14461 ccgaacacga tccatgtcac agtttgcaga cgaagcatca atacaataca agtcaaaatg
    14521 gagacgattg gcaatagcgg aacgaatggc actttgaatt ctccagcttt tggtttgcca
    14581 aacatttttc tcaacttcag taagcctaga ctaacaagca tcaaataggc gagcgccatg
    14641 atattcgtta gttccgctaa tacattcaat gggaaaaatc cggcaaagaa tacagctgcc
    14701 acaccagcgg cataagtcgc ttttttcggt gtacgatgct tttgatcgat ttctgtcata
    14761 aacttaggaa gtaagccatc cttgctgaca gcaaacagta aacgagcaag tgaatacatc
    14821 atcgagatcg ttaccgtcag tagcgttaaa attgccccta cagcgatcac cgcgcccact
    14881 gttccatgtc ctacatacct cattgcaaaa gccactgggt cattgactcc tagttcagta
    14941 tacggaacga ttcctgtcaa gatcagcgtc acgatgatgt aaaggacagt agcaatcagt
    15001 atcgaaccaa tgattcctct tggcacatct ttttgcgggt ttttgacttc ctcggctgcc
    15061 attgcaacgg catcaaatcc caagaaagca aaaaacacaa gagctgcacc atctagcaca
    15121 ccggaaaaac caaaaggcat gaatggctgc cagttatcag gtttaacgaa aaatattcct
    15181 acaatgataa acaacgcgat gataccaaat ttgacatata ccatggcatt attcaaacgt
    15241 aatgctttct tggcttcaag cgacacgatg taagtgacga atatcactac gagcaccgca
    15301 atcaagtcaa tgtatgtacc attttccgga ttgtacccgc cagttaatgc ttgtggaagt
    15361 tcggccccta aacttttcaa aaaaccttgc atatagccag accatccgga agcaacagag
    15421 gaaaccgcta gtaaaaattc cccgatcaac aaccaccctg tcagccaggc agcaaattca
    15481 ccaaatacaa catacagata ggcatatggc ccaccaatca ctggcactcg cgaagcaaat
    15541 tctgcgaaac ttagtccaga caaaatgaca acgattgcag ctaagacaaa tgaaagtgac
    15601 agtgctggac cagcattttg attggccgca acccctgtca ccacaaatat tcccgtaccg
    15661 atgatcgcac caattccaag catgatcaaa tcagacgttt ttagttcttt tttcatctca
    15721 ctcgtatgat tgagattgat ctctttctta cgaaacaaat ccattgaagt tcctccccat
    15781 tttaggttgg aaaacagcga ttaaactgtt ttcatatacc ctaaaaggat accacctaaa
    15841 atgactaaaa ggcaaccaac aataacataa atgagctctt ttttcgtttt tctttcgcca
    15901 aggatgaaaa tcccacctaa agtagagata atgatcccca tttgtgaaag tgagaagcca
    15961 acagctaaac caagtgattt gactgttaga agcatgcaga tgtttcctaa gccccataat
    16021 aatccacaga tcatgttttt ccacacaaac tgatcgactt taactttacg gaaagcaaag
    16081 aagcttgcgc ctaagatcat tccgatactt tgaggtaaga taattgacat cgcatccaaa
    16141 ttcgcccagt tgacgatgat ggtatataca ccataaccaa tcgtagagaa gatcaatgct
    16201 ctaaaaccct taccaaaatc aagcatttta ttatctgtat ctatttttcc ttcgtcatct
    16261 tgtcgggcag tcaaatacgc accgcttaca agaagagcta aagcaataat accgtataca
    16321 taatctttcg tttgtgtcca ttcatggaag aaaacggctc ccgcaatcgt attcaaaatt
    16381 aattgaaaac cagtagacaa tggtagccct acagaaacac ccatgtactt cattccatgg
    16441 aactgtccat tttgtccaac actccaagct aagccggata aaaatccgat caagaaaatc
    16501 caaggggtga ttacaggact aacaacgaaa aagacaacta aagaaaacag aaatgcaccg
    16561 atcgtcattc ctagtgtttg ttgattggca tcgccaccaa ttttaccact tactaaacca
    16621 atactacccc atgccaacat agggactaat gctattaaaa tttccataac caatctcctt
    16681 ttatttcaca tgataagaaa cttatcagcg aaaacgttaa caacacaagc actttttttc
    16741 gtttctaacg attttctaac gtttttcatt ataaaaattt aagattggga aaaataaagt
    16801 cattgttgtc ccttttcctt cagttgattc agccgtcaaa tggataccta atttttcggc
    16861 cagatttttt gctaaataaa gtcctaatcc tgttgaatgt gttttgctaa gtcgaccatt
    16921 tctcccagta aatcccttat caaagatccg tttcaagtct tccgctggga taccgatccc
    16981 tgaatcttta actgaaaggc tgactccttg cgcttccttt tctatgctca caatgatgtt
    17041 tccgtgatcc ggcgtatatt tgatggcatt actaagcaat tggttgaaga taaaagcgat
    17101 ccatttagca tcggtcaaaa cagtatgatc ctcaccaacg atctcgtagc gaatattttt
    17161 ttggataaaa taatttgcct gactgcgtat cacaggctga atgattcctt ttagtccata
    17221 ttcttggatg aggtagtccc gcgagaaact gtcgagtctt gcataataca aaacttgttc
    17281 tacgtattca tcgatttttg ataattcatt ttctagtaat gtatactttt gatcgtcaat
    17341 atcgaactcg atcgaacgaa ctagcaattt agaagcggaa agtggcactt tgatttcatg
    17401 gacccatgag tcaatataat ctttttggtc ttgttgatta ctgattgctg attgcattac
    17461 ttcttggtgt tcacggatca gctgattgat atattcttct accagttttt cttcttctgt
    17521 cctcccacca ctcaaataat tttgcaaagg ggaagttttt tgtatgtcgg ctaattttcc
    17581 ccaccatctt ctcttgctca agtaaccacc cagcagataa aaaatcagaa agacgccctc
    17641 aatcaaagct aaataagcaa ttgtgctcaa atcaactttg atgtttggcg ccagccacat
    17701 cacaaagatc gtcaatgcaa taaaaaacag ccatcccaag atcaatgtcc actgatcttt
    17761 caaatattta aaaaaattca tcttaaccgc tcatcctttc agggaacgat atatccctgt
    17821 cctacttttg tttcgatata tccttggata cctgcctgtt cgatttttcg gcgtaaccga
    17881 ttgatgttga ctgtcaatgt attgtcatct acaaatcgtt cgtcatccca cagtgctcgc
    17941 agcaattttt cccgacttaa gatctttcca ttgtgcttca tcaaaataaa taatagacga
    18001 tattcatttt tgctcaaatc aatgatctct ccgttgattt ccatacttcc gttgtcaaca
    18061 ttcaacgtaa tgccattgtg gctcatcatt tcactagata attctgtgta gttgtaagaa
    18121 cggcgaagta atgcattgat ttttgcaatc agtacatcga tttggaaatg ttttgtcaca
    18181 aaatcatctg cccccatgtt catagccatg atcatatcca tattcgtatt cctgctggag
    18241 ataaaaatga tcggtacttt cgatacttca cgtatttttt gacaccaata atagccatcc
    18301 aaaacgggaa gattaatatc tagtaataca agctgtggtt cttctctttc aaagtctgag
    18361 aacacttgat tgaaatcggt cgttccaaag gtttcaaatt gccatttctc aagttcctcc
    18421 atgatcaatt gtcgaatgat ctcttcgtct tcgactacca tgatttttgc cataaaaaat
    18481 ccctccatct ttcttcttgc tactacaata tcaaagaagc ccttgtgaaa caagttggct
    18541 tacctggaaa atgtcatttt agcaaacgtt aaaaaaaact ggaaatatgc gatttaatcg
    18601 cgtttgtctc ttccaagcag cttaaattta ttatgttatt cttaataatt ggtctattat
    18661 ctgttatttt tctttcgttg tttttgtctt ttaaattttc gataacacca ataaccgaaa
    18721 agcgttagca ctagcaatat acctagaagg agtataagta atcgataaag atggtatttt
    18781 tttgtctgtt ctatctttga agagacttct tctgtaaagg gaactcgtct tcctgtcact
    18841 agtaatcggt gagtgttcac ggtgtaaggt gtacaagtga taagtgtgac tagatcctgc
    18901 ttttctctaa ttgctaatgt atttgttttt gttggaagga caacaatttt ctcaacgact
    18961 tcataagcga gcatccgacc atacacttca agatagaatc ggtcatcttg ctccatttct
    19021 tcaagatccg taaagagttt tttctcagca ataccgctat gggcggtaat cacggaatgt
    19081 gtactctctc ctccagttgg aaaagaggtg ccttgcagga ctgtcgctcc tctatctaac
    19141 aaaagatcat tcgtttcatc aaataaaggc aagctaacat tgattttcgg aatatagatg
    19201 gctccgatca tatgttgttc gtaatattct tttcctggat tttggacatt tctaaccgct
    19261 tgctcaaaag gatctttgac ttgtcccatt cctgggatta ctgatgtatg agcaagcgtc
    19321 tgatttttct tttcatgcac tgctaattgt tgctcatgtt tttcttcttt atcgcgttca
    19381 agctgctttt gataattctc gatccttctt tgatccaaat aattgctgag agcatctgct
    19441 aaaaatggat atgtaaaaac tgcagctccg gcaagaaaca tcactgccat aaataattgt
    19501 aataaaagac tgatttgggt ttgaggtcta ttacctattt tctttttcat tttcttcacc
    19561 ttcttattta aaaaaactgc agcaaccttt ataaaaccga ttgctgcagc ttatttttgt
    19621 tgcttatact tcagacttca ttttagattt acggtaccag ctgtacgctc caatcatcaa
    19681 acttattccg attagtaaga atgccaagag cccgttccca ccagtagcag gaagtgaccc
    19741 gcgtttcata ttcggtactc tttctggccc tggattttct actcctacga tctgaatttc
    19801 ttcattatag cttccataag agatgataaa ttcagtaaag gctgcctcac ctgttggaag
    19861 tacataacct tctggcgcca tggtctcttt catttgatag gttccataat ctaacccttg
    19921 aacctcaaag tatccatttc catctgcgac aaattctgtt gcttgtccgc ttgttgccca
    19981 ctcaattcta tctgctcctg attcataaac agctaaaggc gactcccctt tataaaatat
    20041 tgcgtattca gaacggtctt cattccacaa ttcgaatctt gcatctttaa gcaattcact
    20101 gcttgatgca tcatattttt caaactttct tccacctgtt gtgactttct ctggcggctc
    20161 tactccttct tcataatcaa attcatcatt tcgtccgatt tcaataaccg ctgtgttgtt
    20221 atggaaatca tccgcttcta gttctgtgga aaccttcaaa ttatacgtga tcgttaaatc
    20281 tcctccacgt gcatctgcta atctacctaa agtatctact ttggctactc cattttcttc
    20341 tgtcaaaatc gtcacgacaa acccgttgct tactacttct actatataat cttgtccttt
    20401 tgttaaaatc gtctcgccgg ctcgcacttc tatttcctga tcataataag ttagaccaac
    20461 tgtaggcgta tctgtgattt tgtaattttt gataacagcg cttccgtttt caaggacaga
    20521 atcgatgaaa taaggaatag gtgctgtgat cgtgtaagaa gccgtttttc ctctttctag
    20581 atcaatataa gaaatcgttt cttgttctcc agcttcatta ataatcgtta cttgtctaag
    20641 gtcgctttcc tctacattca tctgtttatc tgcttctctg atttcgtttt tcggatacaa
    20701 atgcacatct gtattgtatg tgtctttcca tgtagaacca tcccacacgc catccaccat
    20761 atcaggcatc atcactggca tcataacaac cattggagac gcgattctgg aaatatgagc
    20821 tggcgaataa gtttctaaga aaagatagac tttatctcta gaagaaggtg cttcttccgt
    20881 cacttggacg gtagagaata ccgcttctcc agcttcattc gttgtttgtt tgtcaatact
    20941 tgtcagtcga tattttaaaa accaactttc tgtgtgccgt ttttgaatcc attcaatcgc
    21001 ttcggcagaa ttaagaccgt cttctcgttc cggtgttaaa ggattatctc gaatcaaatc
    21061 gtaatatact tccgttacgt caaacaaatc aaaatcgact cctggaatat tttcttcacc
    21121 aaaatccgta gaaaccaatc cgctattcgg tcgttcttcc ggaacagatg agaaaccttt
    21181 tttgtgtaat gtaatcgtca cttcacttgg tttttgtgcg acttcttcgg ctttgactag
    21241 ttttccgttc ccgaaaatcc ctattcccgc agtaacgagt aacagtacac tcattcccgt
    21301 gacaatcatt tttttattca tttttttctc cccgttcttt ttttattaat aaaacagcac
    21361 ctaacaataa aagaattcct agtaaagaaa tcaacgttct tgcttcattc gtttgcggga
    21421 atacggacca ttttcctgat tgacctggat tgcttggacc actcggctct ttcggtttgt
    21481 ccgttgtttc ttttacggtc tcgttataaa cacgtggtgt tgcggattca taggcagaga
    21541 ctggaacttt cccggattct aattcagcca tctcctgtcc gttaactact acatattgtg
    21601 gttggccttt tgcatccacc caaaattcag ggatgatgac ctcgattctc ttacttgctt
    21661 catccatctc gtaaccttcc acacctttta attcttcaaa ataataggtg ccagaaggca
    21721 agaaacgttg tcctgtcgta acaaggccct ctttatccga aatgaatttg cttacatttt
    21781 tgtcattcaa aggatcattg tctgctggtt tgatccattg atttttcaag tcattagcag
    21841 gagccatatc taaataatat ttcccccctt ctatcatctg atatagagca aaaacagcac
    21901 cttctaatgg ttttcctttt tcagttgttc ctctttgacg tccatacttg aagaagtatg
    21961 gatctcttag ataaccgaca tttttaggat agatatgaat ctcttgcagt tcctcggttg
    22021 attctgtcgg gtgataaatt ggcaaaatag cagcaattgg gatagctgtc tgatcgatat
    22081 caacatccaa tccaacttct ggatcaatcg attcttcgaa aatcaaataa actgcatccc
    22141 gatcttggtt tttcttaggt gctttgatac gtgcaatccc gtctcctaat ccgccaaccg
    22201 tatctttccc agttgttacc gaagtcccta tttggacaag cctttcttct gtgattagct
    22261 gacggatatt gtttctgttc gtttcagcga tttgctggac gaattcttta ggagtcatgt
    22321 tttcagcagc ttttttttca tgataataat cggtcatgtc gtaaatggca aatgtcgctc
    22381 catttagtgg caccgtctgt gaaatgatat ctgctgtttc ccctgcttcc tcagagatag
    22441 ccaagccatc attttcatgg tattcaaatt gatcgttata atcgatatct cgaatcatcc
    22501 gtttatgcaa cacgaattcc acgacatctt cccctgattc ttctgccgac atcgcatgtg
    22561 gaagaaggac tgctgcaagc ggtagtaaaa caagtaattg aagcatcaaa cacaacagct
    22621 ttttcattac cttgctccct cctttttaga ttgtctgaca aacaaaccat aggctgctcc
    22681 tgcaagcgcc atgaagaatg cagcaagcag gatatagaat aatcgtccgg atcctcctgt
    22741 agcaggcaac ggattttcag gatcgttccc gacactaagc tgtaatctga ttcgatttgt
    22801 ctccaaaagt tcatattcta actcttgctg tagatcaggc gtctctgctt cttcgtttgg
    22861 ataatacgaa atctcaactt ttagtgtacc cgcttctttt cctggaacta cccgatcatt
    22921 ttctatgtca ggttcttctc gataactaat ttctaaaata aagtaacctg gaagttttct
    22981 atagctgtca ggtgacttca cttccttgat ccgatagacc ccttccaaca agtctgaagc
    23041 attgaatagg gaagaatcgt ttggatctgg tgccaagcct ccctcgatga tttcatactc
    23101 tcctgcacta ttttgtttct caattgaaaa ttctgcgcct tcaagacgtc ggctattcat
    23161 actgtcaatt ttcaaaagtt ccaaatcgat tggcgctagt tcatcttcta aggttacttg
    23221 tagtacacca tcgatgattt catagccttc cggcaaggga gcagtttcgt cttcgatgac
    23281 cgtatcttca atgataaact taccttcttc attcagtgca aactggaaca cttgatcaga
    23341 tagccgatac ccatttggtg cgacagattc cgagacctca tattcaccaa tagacagatg
    23401 cagaggttgg tcgtaattta aatcgacata cttttctact cctacggcac gagaatagaa
    23461 gtatccgatc ccaggcaaac gtttcgattc ttctggttct aacggattac cagtgtatgc
    23521 tcgatacagc gggaaggaag aatcccccac tttcctgata tcgaaacctg caccatctaa
    23581 tgtatggcct tcatggtcta attttctaac tcggatctcc cgataatcaa acgtattgta
    23641 agcagtgaat gctacccata aacgatcctc ttcatctgtt gtatacgtga gatattgcca
    23701 attttcttca cctgtttgct tgagttggat agtccctata gcattatcgt aaagtcgcaa
    23761 gatccatgtg tcattttcat caggttcttt gaaaccttct gggttctggc tctcaatgat
    23821 tttgtattct gcatagttgg tagtttcttc actatcctta taaacaaatg aatctggctc
    23881 tccgattgga tgaataactt tctcaccatc cacgattaca tatttcccgt cttcatctac
    23941 tgaatagaac gtgagtctcc ctttctcttc ctctacttcg ttcacaccag aaagcccttt
    24001 cgctactgga tatccgattt ccagtccgtt accatctgtt tcataaagtt caaactctgc
    24061 gccattgatt ggcatattac tgccttcaat tagtttattg atattcatgt ggattggctt
    24121 gaattcattt cgcatttcca gtttgacata caactcatca tactctgtgc cttctatgtt
    24181 aggctcttgt acaacagaaa gcttgtgata ttctccttca taataggaat tcggatcttt
    24241 accttccggt ccgccgactc tcgaaccaga tgtatattca tctacaagct cgtagtgacc
    24301 taacatctca tcttcgttgg ctgcatattt tttgatttgg aattgatacg tctcatctac
    24361 taactgataa cgtggtggtc cagcgatctc tctgatccaa aatatgtcgc tgactgctcc
    24421 agtttcatct cctaaaatcg gcatcttcgt ttcaaagatc gctattccgt ccgtggtagt
    24481 tttacttgtt tcgattggtt cggcttcccc actctctgga ttttggtcat ataatgcaaa
    24541 ttcgactcca gccaacggct cgccattttg acccttcttg ctgacttgga aattacggcc
    24601 tttatgttcg taacgaatgg aagaagatgg gaaatacatc cgtccagtag tgatatcatt
    24661 ctcataatcc tccaggttct gaatataggc catattgttc actgtgcaaa aatttccgtc
    24721 ttgagctccc gcatcaagtt ttacttggta cttgatcctg accatttccc cttcacctaa
    24781 agaaatcgga gaaaatttat aagcttggtt ttcccgtccg acatacgttg tcggagtcgc
    24841 cactacttct ggtggggctt gtccatgacg ttcttcatcc catatttctg gctcttggta
    24901 cttcatgccg ttttctcctg gatctagatg gtaaaactga atatctgccg atctgccagc
    24961 tccaaatggt gagacattaa aaccagtttc atcataaagt gtggcttgct ggatcgttct
    25021 cttgaaggta gaagagatat cctccaaggc tgtaacaatg tcattcttgt tgttcgcatt
    25081 gtaatatcgc ggtgttacgc catcttcttc taaatcagca atatttttca atacatttcg
    25141 tccaatagca tctagtcgtt gtctcccgct aacgtttcca tcgattccta aaccaatgga
    25201 gaagatactt ggcgggttct cttgatactt gtttttcagc caatgatgat aagcaactgt
    25261 gttgatcgca gatgactttt cttgcgaagt aggactgcca ttcgtattgt tattagaaga
    25321 accatcacca acccagtgag tcgctttatt atctccttct tttacctctc cataacgata
    25381 gtgtacattt acttcatctt ctggacggtt aaagtcagat gcataggtaa ctggatgagt
    25441 aaaccctgca ttagaagtat tcccagaaaa ctcctcaaaa tttctgaaca aaacgtcatt
    25501 atcttcagca atcttatctt ccatcacagt ccagttgctc caagctccat tagtgctcgt
    25561 acgataactt gactgaatcg gtgcataact gaaggtcggt gtcccatctc ccacaacgat
    25621 taggattttt tctggatttc tattttctcc gccattgtct ttatacaatg tttcatagcc
    25681 atttttaagc cctagtgtaa gcggagttcc tccgattggt gtacgattta atgctgtatt
    25741 ctcacttccc gtcaaacgat tgatatcatt tgtcaatgga aagatgtccg aactgatttg
    25801 ctcatggtta ttgatagctg tactattatg gtaaaaattc accataccga ttcgaatatc
    25861 cagactcggg tcagagagca gatctttact catttcgttt actgcctcaa tcaacgcagc
    25921 atttttagtt tgactattgg tcccagcggt taattcactc atactcgctg acttatctag
    25981 aacaaaaacg atatcgattg gactgatttc ctttttctcg cccccgatga catctagata
    26041 gacattgtaa agggttgttg catcttcagg atgtagatca gatgctgtgc tgcttggcag
    26101 aacaggttct acccattttt tgatgtacgc cccgttataa tccaagtaac tgttttcaaa
    26161 attccgttca tttccccaaa gctgaacggt ttgagctgga acgtttctat cttcttcgcc
    26221 tgcagttgat ccattattag tagcatagtc gtaatttcgc cagttcgctc ccccgtttgt
    26281 ataatcacta tcatcgatca agttctctcc gtcatatggc gagcctttgt ctccttgata
    26341 gcgttcattg ctttgtgtcc aatttcctaa cacttttgta tagtcattcg ttgtaaactt
    26401 cgggtagcga tgctgttcgt tttcaacttc tccgctagga tagatatatt cataggggtc
    26461 ttgcgtagct gttggcccaa gacgctccaa aataccgttg aataactggc gttgaatgcg
    26521 ctggagtgct tgaccgctgg gtacgattgg ttcgtccagc ttttccatct cattttcttc
    26581 gctacgttga atttcagcgg aatcttctgt atcagtttca ttttcttgta attcttggtt
    26641 atctattctt tcatcaacca ccacttgaag aggtagttac ccttcgttca catcggggat
    26701 cttttctgtt tcaaaaatca atgtgccggt ttctgcttct tttgaataaa cttttccgac
    26761 ataccattct tgaccatcga tcgtctcgac ttttaggtct tctccatctt catcatagga
    26821 ggatagacct gttccacgaa cgttttttac ggtaccaatc ccggcggctg ccgcatcgat
    26881 tgctaaacgt attctacctt cattggcact ttcctttttt tcaaaagcca gatgccattc
    26941 aagggtttct tctttttcaa tatacttccc ttcaattttt gcatagtcct catctaagaa
    27001 tacctcatcc tcctttgttt ctgttgactc agcagctaca tccagggtcg tcatatgata
    27061 gactgactgg aaatatggtc caaatagcaa actgacagtt actaactgca aaagcttcaa
    27121 ttttaaccct ttcacatcct tatactcctt tcaaaaatat ttgtcttctt tcacaacaat
    27181 caacaaaaca atgcccatct aattataatt taatttaatt ttaattttaa atcaaatgat
    27241 atccttttta gttaaaaaac accaattata caacatttat tattaaaatt aaattataaa
    27301 attttataac gttctcattt aacaaaactt aagttattaa gacaaatgaa taaacaacta
    27361 cgctttcctc gaaacaaaaa aataaagcac aaatgcgcat ttacgcactc atgctttatt
    27421 cgtacaatta attcagataa cggcagcgca taggatgcca ataacacttc ctaaaatagc
    27481 tcctcctaaa atgtcagtag gataatgtaa aagtaaaaaa atcctcgaat aagcgatcaa
    27541 acaagcaaat aaaaaggcta atattcctgc aactggactt aattcgaaca acgcagctac
    27601 tgataaaaag gctagcgctg tatgtcctga aggaaaagaa gaagtcttcg gtttacttgt
    27661 gtaaaggaca agccgacgat ttttttcata aggtcttttc cgtcttgtcg tttttttgat
    27721 aaaaagcaaa ccaacaaaaa aatagatcaa actgccgata agaatggcta gaccatattc
    27781 tctagtatca ggtatcaaga ctaaaacagc agcaaggagc aaccaaataa aaccaccatt
    27841 agagatatta ctgataaatt tcaaaaaatt gatttttcga ctatccgttt tccgttgctt
    27901 ggcgaacttg ttgataatac tatcatcgat tttagcaatc aaacgcaaca tgttattcct
    27961 cctttttaag aaccttttct tgcgtacgat ggataaaaag caggacttga aaataaaaca
    28021 agaaactgaa acctaataaa gcaaaataga ttggtcctgc aaaccagaat gcgacaagaa
    28081 ggatcaacgt gcctgccaaa tagaaaagcg cgcttttgaa atcattaaaa aacaagaaaa
    28141 atgcagtaat ccaagaagct tctttttgtt ccagttgaag caagattttg taactaaaga
    28201 gaagcgcgct taatagaagc aaaaacaacg tagtatacat caatgtatag ccaattcccc
    28261 caccccaata gcggaaaatc tgataatcga tcaatagaag aagaaaataa acacttgcta
    28321 aactatcttg ctttccataa agagagaagt tctcacgaaa ctttttccag aatagtgaac
    28381 cgagcttttt ctcttcattt tttttgtaat gataaatcat atacagaact gttcgacttg
    28441 cagttcctaa tgtgaaaaca ggcaagacgc acaggaacca tagtagctgt aaatggataa
    28501 gacgtggaat ccattcaatg atttctaaga aataatcatt ggctttttta ccaatcgatc
    28561 gattcatcat ccttttgaac ctcctgtcaa atccatccct tcaatgaaat aacgttgtgc
    28621 aaaaaagaac agcaaaatcg tcgggatcaa gacaagtgtt gctcctgcca tcagataatt
    28681 ccattgtgtc gttgcttggt tctgaaaaac ttgcaagcca atctgtaacg tgtatttttc
    28741 ttgatcttgg atatataaca gaggacctaa gaaatcattc caagctgcgt tgaaggaatt
    28801 gatcgcaatg gtaatcaagg caggtttcgt caatggaagc atcaaatgac tccaaatata
    28861 caaatgattc gctccgtcga tttcagcagc ttcgatcaat tcattattga tcgataagta
    28921 aaattgacgc atcagaaata tattgaacgc attgccgaag aacgatggaa cgatcagggg
    28981 caaataagta cctacccagc cgatcttgga gaataataca tattgaggga tcatcgttac
    29041 aaaccccggg atcatcatcg tagaaagaac caaagcaaac atcagctttt tcccaggaaa
    29101 atcaagcttc gcaaatccat aagcaataaa agaatttgaa aggacattac cgatcactac
    29161 tagcacagtg atgaataatg tatttcttgc atagcgccaa aaaggaaagg cggcaatcgt
    29221 atccagatag ttttcccata cgattttttc tgggaaaaag gtcggaggat aacgaacgat
    29281 ttcttccatt ggtttcaatg aagtaaacac catccaaagc aatggaatga tcaaaatgat
    29341 tcctattact gtcatgagga cataacttag tatttttttt gtttgccgat tcacactggt
    29401 ctttttgaaa taatccatca tttgccgtca cctccagaat aatagaccca cttaggtgca
    29461 agcttcaaat tgacaaacgt cagaaccaac acgatcagaa acaggatcat tgacatagcc
    29521 atcgcataac ccatatcaaa agctacgaac gccttgttcc acatatgcag attataaaaa
    29581 agcaaagaat ttgcaggtcc gcctgttcca tttttcgtca tgacataagc ttcttgaaaa
    29641 atttggaaag aaccgatcgt agaggtgatc acatcgtaaa aaataatagg agtgattaat
    29701 ggcaaagtaa tacttttgaa ctttccccaa acgcctgctc catcgatttc tgctgattca
    29761 tataaagatc taggaacatt ttgtaatgta gctaagtaaa gtagcattgc tcctccagaa
    29821 ctccatattt tcatcaaaat caacgcaggt ttcgtccatt gtggatcaaa cagccaagct
    29881 ggtccaggga tatggaacca gcccagaaat gtgttgatca atcctgcaga tggagaaagc
    29941 agctgcatcc ataagatgta gactgctact cctgataaga ctgccggtaa atagaaagct
    30001 gtacggaata cactgattcc tttgattttt tgattgagta ctgtggctaa aaacacactg
    30061 aaaatcgtcg tcagcggtac attgaagatg acgaaataaa cggtgttgta taacgatttc
    30121 caaaataaat catcgtgaac gaacattctt ttgaaatttg ctagaccaat gaaattcatc
    30181 ttggatgtca aattataatc ggtgaaacta ccaataactg aaaaaagcat aggccctagc
    30241 ataaatacca agaacccgat aataaaaggc gagataaata aataggccca tcttgcttct
    30301 tttttctttc ggatagataa acgcttcaaa ttttcttgcc tcctctgtac ctagacagtc
    30361 aaaaatggat tattgatttt gcttgactaa gttttctact gctttttgtg catctgccaa
    30421 tccttctttt ggtgattttg ttcctaaaag aatctggtca atctgttcat tcactaatgt
    30481 cgtgtaatcc ggagcatcta aaggaactgg tgtgatcacc gtatttttaa agttttcgtc
    30541 cgccatttga tagatcattt ttcctttatc cgttaggttg tcattattca ctaaattctc
    30601 attggctgtc ttgctcgcca tgatatcaaa acttttttcg ccgaattttt cttgtacttc
    30661 tggagaagaa agatatttga tgaattcata agaggcctca ggatcttttg ctccgtatgg
    30721 tacttccaag acgaatccgc caccccacga ccaatggcct gaaccttctt ctttttctgg
    30781 gagctgcatc acgccaaaat caaaatcatc cggtgcattt tccatcaaac tagagtaata
    30841 attgatattt tgggcacgca tggctactaa tccggaaata aatggatcag atacaccaga
    30901 cccaaattcg gcttctaatt tattgatcgt atttttccca taataatctt gccagtcttg
    30961 gatccactcc aaggcttcca ctttattttt agtatcaatc ttgacttttt catctttgtc
    31021 aaaccaacta gtcccgttat ctgcgtttag cgcccataca tcagccccta aattccataa
    31081 tggataaaaa ccgatgcgtg taaattcttt tccttctttt ttatctagtt tacgtgctgt
    31141 ttcttctaat tcatcccaag ttgtcggtag atcttgttca ctgattccag cttctttaaa
    31201 taacttttta ttataaaaaa tgacttgtgt atctgtattg aatgggatcg cataaggatc
    31261 accttcatat tctactgtat cccaaagctg cggataaaaa tccttagaag tgtctttttc
    31321 tacatatttg gagagattag ttgcttgctg tgcttctgct ctttgggcaa cggaatttat
    31381 gtcctgtaca ataacatcgg gtgcatttcc agctgttatt gcagataaag atttagtcca
    31441 gatgtcaccc catggctgat acttataatt tacatggatc tcgttttgtg attgattgaa
    31501 atcctcaatg atttcttcga tagcttcttt tcgtgcaccg gatccccaaa aggaccagaa
    31561 atcaatattt tttcttccat cacttgtttt ttcagaagaa tttgctgcac ttgaactggc
    31621 atcgcttgca ttacttgatc cgcatcctcc taataaaaac aatgctgaac ttgccagcaa
    31681 ccctgtaaac aataattttt tcatatttta cctccaaatt ttaatgtaac cgatgccggt
    31741 tttaatataa cgatatcatt ttgttctgaa aataacaatt tataaggtat gattctaaaa
    31801 aaattattaa tgataccaat actttatata attcgcgagc gctttctttg aattttttaa
    31861 tctttcgtag cagaatgaga atgtattaaa aatagattag gaggaatttt gatgtttaga
    31921 caccagaaag aattgcagtt tgaagcaaaa ccagatcgtc cgaatccatt aatcgcgaaa
    31981 tatctgcagg agctgatcgg cggccaatat ggcgagatga gtgtagctat gcagtacctg
    32041 ttccaaggct ggagctgccg aggagaagaa aaatataaag atatgctgat ggacattgca
    32101 acagaagaaa tcggccacgt ggaaatgttg gcgacaatgg ttgctcgttt attagagggt
    32161 gcgcctgttg aagatcaaga agcagcgatg caaaaagatc caacaatcgg tgccattatc
    32221 tctggaatga atccacagca cgcgatcgta gctggcttag gacctcgtcc tgctgacagc
    32281 gtgggcaatc catggagcgg tgcctatatc attgcgagtg gcaacttgtt agcagacttt
    32341 agagctaatt taaatgccga atcacaagga agacttcaag tagcacgtat ttacgaaatg
    32401 atcgatgatc gtggcgtaaa agatatgctg tctgttctcc ttgcaagaga tagctatcat
    32461 caaaatctat gggaatgtgc agtgaaagaa ttagaagaaa aagaaggttc aatcttagtc
    32521 ccaagtactt tcccgcgtga caaagaacga aaagacattg cttatgactt ctataacttc
    32581 tcagagggag accaaagtag tgaaggttct tgggctagtg gcaaagcact ggatggcgaa
    32641 ggcgaatatc aatggttgaa agaacctaag atcgaaggcg ctgcaccaaa attagaacca
    32701 gtaacaccaa aaatgtatgg gacacctcca ttcaagaaat aaatatctac ccgtagaaac
    32761 acccgttttt tgttccacac gctttgtgag caaaactgac taaagtcatt aatcataacc
    32821 acccttcaaa agggtggttt tctctagagc tataagctca aatcaccggc cagcgcctaa
    32881 agacgctggc tttcatattt tatgttcaag ccatattgcc tttgccagtt ttgcccacct
    32941 cttaaaaggt ttatgtacta ctccttagcc cttaaaagga tcgtcttact ctcgtacact
    33001 cagcttatct aacgcactat catgtttttc ttgttcttga atgtactttt tgatggtcgc
    33061 ttcattttgt cctacttttg tcacatagta tccttccacc caaaagtgtc gatacccaaa
    33121 tttatatttt agatttgcac aatctcttga tgatctcctg aatattggct cgatattgat
    33181 tataaattat ttttcttcta tactttggtg tgaatacaat gtggtattta cacatctact
    33241 ttgtacgggc taaactattt ccctttattg ctccacccgc atagcaagtg gttttgtatt
    33301 tcaatcgctc ggcgcgctca attaggtcta aagacaataa atctaaaaac ccgctgcttc
    33361 actgacagaa acaacgggtt ttcagaaaaa aatgaaatga aaaagatctc ttacggcaat
    33421 ctattttatt tttttgattt tttataaatg gaaaatgctt caagaagtcc aagaaataaa
    33481 gccgtataaa aacaagaacc tatgaaatct ttatttatta gatattcaac agaaatcccg
    33541 ataacactag ccaacaatat atttatcaga agtgtaaaat aaggatgctt tttatagaat
    33601 agaactagtg ttgttttcat agactctcct ttcttcatat ttccaattaa tcacaaattc
    33661 acggcattac tagaaaaatt aaaggggcgc agaagtggaa aaatactctt cgactttccc
    33721 tacaaaccag gccatcttgt gtttaataac tataccaaat ctaaggtacc tctaaatcta
    33781 aattccattt gtggcggtga cctccaattt ttaactcttc tatctcccat ccagtataca
    33841 taaccttgat acttcgacca cttatatatc gaacacacaa atacctatcc attgcaggag
    33901 tactacctaa cttagttgct acttgcatct aaataacagc tgaaaagata ggacttactc
    33961 ttagtaaagt atctgaacta ttaattttta aactatcatt tttatcctca actacatgca
    34021 catctgttgc aacttcactt tctgtctcat ccagataaat gattaaggaa tcgggaattg
    34081 caatatcttc agctgacgct ggaatagttg agctaaatta gtcatcatat ctttattata
    34141 aaataaccaa cagcaaaaaa tacaatgaaa aacaaacttg gaactaatgt atcattaata
    34201 aatgttgaaa aattcagcaa ctcattactg tatgatttta gcagcccaac caacatatac
    34261 cctataaaag ctaataagat ggttaggaat cctttagaat ttttactcat tcatagacac
    34321 ttccttaaat aacttttatt atagaaggta ttgtaaataa taatattgac aaaaagtgac
    34381 tcaaaataaa aaaaacctta cattatactg gaatgaactg tattgatagt gtacctaaaa
    34441 gctctactga cataagatcg tgtaatcggt aaagtaattt tattaattat acgggatgta
    34501 atcaattaga gaataaacta atcataaaag gtacttttac attcataatt gtcgctttga
    34561 gattctactt tggttcacta tctgacccaa ttgcacattt tcgatcatta caagtattgg
    34621 tgtcgttaga acaactaaat aaaaactagc ggtagatttt tcagaatcta tgctaatttc
    34681 tgtatggatg ttccagtgat ggcaaatttc tcttttcatt gtttttcttg tcgcatgata
    34741 tgcctttttg tgttattcag ttaaactata gaaattcttt cctagacaga tcttgatccc
    34801 aaattttacg tttttgagca tcgatatagt ttaaaatgac attactcata tctaaagagt
    34861 ttagattttt taggactaaa actgtcagtt gttctttttc ttctttctgt taaagtattg
    34921 tcgcgacttt tcgtatacgt taagatatgt cgtgaaaaaa caagttttgt gacacaaaaa
    34981 aacgaatgac ttgaggaaat cacctcaatc attcgtttaa aatgctatat attctttagt
    35041 ttaagatacg gaaattaatg ccatcgacca cactagtaga atgaacgaca tttacttggc
    35101 ctttttttaa tttcgttatg tttagcatat aaaaatatta tagagtttac ttacaatgct
    35161 taaaacatat actgtataat ctgatcaatt ttagccatgt cttgcaatgg taagttttct
    35221 atttttttga gttttcgttc cttaaaatca agagatttta attgtgtaat aattacttgt
    35281 ccttttatat ctagctcttc aggtaatgag taacgtgtcg gtaaattctt tatagtggaa
    35341 gtaattggac atatgaccga aaacattgtt ttacggttaa attcataacg agagacgact
    35401 agtcctggtc gtcttttttg aatttctttt cctacggagg gatcaaaatc aatccataca
    35461 atatcacctt ttttaggaat ataaattctt tcttctgaca ctataaaatt tctctccctt
    35521 caggagttaa atcttcccat tcgtctttct cataatactc ggcctcttcc ccaccactaa
    35581 atggatcttc aatttttgga actaacgtaa ttgttccatc atcagaatac acaacgatat
    35641 attcttggtt ttctgaaggt ttctttccgt tatcagaagg taaagttacc actacagaac
    35701 ttccttgtaa tctagatttt gtaacaagca ttatcatcac tcccttaata aaagtatact
    35761 atataacact aagtaacgca aaattcccct ttgtaaacta tctagaaaat tgttttgttt
    35821 aaagtatatc ttattggata taaatagaaa taaattgtag ccagttcatt ttttctttaa
    35881 ctaaaaaaat aatccaagaa acattgaacc tatggatcca aaagctaccc aaatactata
    35941 gctaaccccc cgctaccttc aattttgcag ataaaacgct ttgggagaaa atttcaaaga
    36001 caacaggcca tcctatcatg cccgattata aacaaaaagc tggctattcc ttttgctctg
    36061 acaaatttca attgggaaag ttcacgaaac tagcaggtga agaagtttca actgttcgga
    36121 tcaaagaatg cccgcttcaa atagaaacat tggttcaacg aatttcaact agacaagact
    36181 ttgctattgt agaacgtgag atcgtagcta tttttgtaga agaagggatt ttacatgatc
    36241 caactcatat caatgtggat aaatggcaac ctcttatcta taaattcaga gaatatacaa
    36301 ctgccaacca gtcgttaact ttgaatttta gattccaaga attcaaagag tcataatgat
    36361 aaacatcgtt aggtataaat aaaaaagact cgcagcacga gtaaaaaaca aatagaagct
    36421 atacattaga aaggtcgact gtgaccctat agatgcagta tatgcagctt atgagcattt
    36481 cttctgttct ctttgttttt gggatctgtg ctgaagtctt tttcgttttt tgccgctctt
    36541 tctttgaaaa atcgattatg ttataccttc tccattacta attcaggcat ctgctgagta
    36601 atgatttttc gcgcaaaaga aatatctgtt acccaaggtt cgatttgttc ttcagtcaag
    36661 acaagcggca ttcggtcatg gattggtgcg actgtgcggt taggttcagt agtcattatg
    36721 attgattctg ccattttttc atcctgatgg ctacgataaa aaccgccaat atacactatt
    36781 ttttccttat ttgaaaacat aaatttgtct ttttcttcat tccactcatt gggaaaacac
    36841 aacgattttg caaaaatggt tgatgaaagg tctttttttc ttctactgtc tctgcacggg
    36901 cattaatcat caattgtcct tttttaaatc cggtaaatcc ccacttcatg atttccggag
    36961 tgaggatgtt ttcttcctct tttcttaacg tcacaacaag atttgacgga aaaacttctc
    37021 cagctgctaa ttctgctgcc tgcttcggtt gtttcgtctg ggcttctcga taataattct
    37081 gaaggagctc tgactctaga tcaaaaaaat aacgaccaca catcctaatc cctcccaatc
    37141 tttttttcta tcatacactg caacaagaag ttcgcaccaa caaaacgctt tcaatttttg
    37201 tagaactaaa aaagttgtga caagtgacaa actctccagt gaatggtatt ctcctgccaa
    37261 ctcctcggtc acaagtcaca atattcaaca aacatgagaa gctgcttttt gaaattgttc
    37321 cttgtgactc ggagtgaaac ggcaggctta cgacctctgg gtaaacggtg ttcaaaagcc
    37381 agtttctcgg tattaagcca aatttatgca aaaatgtaga aagctatttt cacaaaattt
    37441 ttcttaatac tcgaaactaa gcgacttttt cacaacctct tccttaaacg gtgttcaaaa
    37501 gcttgcatct gcggtaataa gcccaaccaa acgaaaaata tgagcagcta tttttatttg
    37561 gctgttctta ttacttgatg cagggcagct ttttcacaac ctctccacta aacggtgttc
    37621 aatcagctaa ccttcggtat tagctcaaaa aacggcaaaa tatgaggaac tattttgccg
    37681 tttgtttctc taatactcag gtcaaagcgc tgatttcaca acctctaata cacggtgttc
    37741 cagaagtagc ttcttcga
//
LOCUS       DADGHT010000015        37534 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.015, whole genome shotgun sequence.
ACCESSION   DADGHT010000015 DADGHT010000000
VERSION     DADGHT010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.015"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1008)
                     /locus_tag="JX887_000680"
     CDS             complement(<1..1008)
                     /locus_tag="JX887_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1256689.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="JX887_000681"
     CDS             complement(1188..1532)
                     /locus_tag="JX887_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAX1256690.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="JX887_000682"
     CDS             complement(1525..1959)
                     /locus_tag="JX887_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAX1256691.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="JX887_000683"
     CDS             2097..2834
                     /locus_tag="JX887_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256692.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="JX887_000684"
     CDS             2827..4038
                     /locus_tag="JX887_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1256693.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4245..5024
                     /locus_tag="JX887_000685"
     CDS             4245..5024
                     /locus_tag="JX887_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAX1256694.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="JX887_000686"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="JX887_000686"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAX1256695.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="JX887_000687"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="JX887_000687"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAX1256696.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="cpaF"
                     /locus_tag="JX887_000688"
     CDS             7740..8669
                     /gene="cpaF"
                     /locus_tag="JX887_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAX1256697.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /locus_tag="JX887_000689"
     CDS             8626..9675
                     /locus_tag="JX887_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAX1256698.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /locus_tag="JX887_000690"
     CDS             9672..9950
                     /locus_tag="JX887_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAX1256699.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /locus_tag="JX887_000691"
     CDS             9925..10395
                     /locus_tag="JX887_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAX1256700.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10412..10714
                     /locus_tag="JX887_000692"
     CDS             10412..10714
                     /locus_tag="JX887_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256701.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10731..11102
                     /locus_tag="JX887_000693"
     CDS             10731..11102
                     /locus_tag="JX887_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAX1256702.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /locus_tag="JX887_000694"
     CDS             11074..11433
                     /locus_tag="JX887_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256703.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="JX887_000695"
     CDS             11605..12612
                     /locus_tag="JX887_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1256704.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="JX887_000696"
     CDS             12637..13821
                     /locus_tag="JX887_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAX1256705.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /locus_tag="JX887_000697"
     CDS             complement(14258..15841)
                     /locus_tag="JX887_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAX1256706.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16419..16562)
                     /locus_tag="JX887_000698"
     CDS             complement(16419..16562)
                     /locus_tag="JX887_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAX1256707.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="JX887_000699"
     CDS             complement(16785..17264)
                     /locus_tag="JX887_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAX1256708.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="JX887_000700"
     CDS             complement(17337..17621)
                     /locus_tag="JX887_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256709.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="JX887_000701"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="JX887_000701"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="JX887_000702"
     CDS             complement(17965..19251)
                     /locus_tag="JX887_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAX1256710.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="JX887_000703"
     CDS             19389..20060
                     /locus_tag="JX887_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAX1256711.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="JX887_000704"
     CDS             20026..20514
                     /locus_tag="JX887_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAX1256712.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="JX887_000705"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="JX887_000705"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAX1256713.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="JX887_000706"
     CDS             21475..22239
                     /locus_tag="JX887_000706"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAX1256714.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="JX887_000707"
     CDS             22472..24685
                     /locus_tag="JX887_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAX1256715.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /locus_tag="JX887_000708"
     CDS             24696..25142
                     /locus_tag="JX887_000708"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAX1256716.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="JX887_000709"
     CDS             25313..26572
                     /locus_tag="JX887_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAX1256717.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="JX887_000710"
     CDS             complement(26661..27608)
                     /locus_tag="JX887_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAX1256718.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /locus_tag="JX887_000711"
     CDS             28002..29294
                     /locus_tag="JX887_000711"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAX1256719.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="JX887_000712"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="JX887_000712"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAX1256720.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="JX887_000713"
     CDS             31187..32062
                     /locus_tag="JX887_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAX1256721.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="JX887_000714"
     CDS             32328..34211
                     /locus_tag="JX887_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAX1256722.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="JX887_000715"
     CDS             complement(34286..34570)
                     /locus_tag="JX887_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAX1256723.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="JX887_000716"
     CDS             complement(34560..35294)
                     /locus_tag="JX887_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAX1256724.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="JX887_000717"
     CDS             35423..36046
                     /locus_tag="JX887_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAX1256725.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="JX887_000718"
     CDS             36238..37359
                     /locus_tag="JX887_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAX1256726.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..>37534
                     /locus_tag="JX887_000719"
     CDS             37366..>37534
                     /locus_tag="JX887_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1256727.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETS"
BASE COUNT        11731 a         6686 c         7908 g        11209 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaaggcaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgag aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaatta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgattgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccg
//
LOCUS       DADGHT010000016        37256 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.016, whole genome shotgun sequence.
ACCESSION   DADGHT010000016 DADGHT010000000
VERSION     DADGHT010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.016"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..247
                     /locus_tag="JX887_000720"
     CDS             <1..247
                     /locus_tag="JX887_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAX1256728.1"
                     /translation="TETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(331..1053)
                     /locus_tag="JX887_000721"
     CDS             complement(331..1053)
                     /locus_tag="JX887_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAX1256729.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(1043..1780)
                     /locus_tag="JX887_000722"
     CDS             complement(1043..1780)
                     /locus_tag="JX887_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256730.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(1792..2784)
                     /locus_tag="JX887_000723"
     CDS             complement(1792..2784)
                     /locus_tag="JX887_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1256731.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(2799..3542)
                     /locus_tag="JX887_000724"
     CDS             complement(2799..3542)
                     /locus_tag="JX887_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1256732.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(3616..3720)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3783..5105)
                     /locus_tag="JX887_000725"
     CDS             complement(3783..5105)
                     /locus_tag="JX887_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAX1256733.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(5092..6057)
                     /locus_tag="JX887_000726"
     CDS             complement(5092..6057)
                     /locus_tag="JX887_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256734.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(6054..7592)
                     /locus_tag="JX887_000727"
     CDS             complement(6054..7592)
                     /locus_tag="JX887_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAX1256735.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(8008..8295)
                     /locus_tag="JX887_000728"
     CDS             complement(8008..8295)
                     /locus_tag="JX887_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256736.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            8429..9097
                     /locus_tag="JX887_000729"
     CDS             8429..9097
                     /locus_tag="JX887_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAX1256737.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(9388..10128)
                     /locus_tag="JX887_000730"
     CDS             complement(9388..10128)
                     /locus_tag="JX887_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256738.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(10258..11205)
                     /locus_tag="JX887_000731"
     CDS             complement(10258..11205)
                     /locus_tag="JX887_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1256739.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(11334..12098)
                     /locus_tag="JX887_000732"
     CDS             complement(11334..12098)
                     /locus_tag="JX887_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAX1256740.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(12102..12491)
                     /locus_tag="JX887_000733"
     CDS             complement(12102..12491)
                     /locus_tag="JX887_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256741.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            12626..13168
                     /locus_tag="JX887_000734"
     CDS             12626..13168
                     /locus_tag="JX887_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAX1256742.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13316..13948
                     /locus_tag="JX887_000735"
     CDS             13316..13948
                     /locus_tag="JX887_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256743.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(14082..14207)
                     /locus_tag="JX887_000736"
     CDS             complement(14082..14207)
                     /locus_tag="JX887_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1256744.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(14341..15234)
                     /locus_tag="JX887_000737"
     CDS             complement(14341..15234)
                     /locus_tag="JX887_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAX1256745.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(15416..16342)
                     /locus_tag="JX887_000738"
     CDS             complement(15416..16342)
                     /locus_tag="JX887_000738"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAX1256746.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(16427..17188)
                     /gene="pflA"
                     /locus_tag="JX887_000739"
     CDS             complement(16427..17188)
                     /gene="pflA"
                     /locus_tag="JX887_000739"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAX1256747.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(17432..19663)
                     /gene="pflB"
                     /locus_tag="JX887_000740"
     CDS             complement(17432..19663)
                     /gene="pflB"
                     /locus_tag="JX887_000740"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAX1256748.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(19940..22390)
                     /gene="parC"
                     /locus_tag="JX887_000741"
     CDS             complement(19940..22390)
                     /gene="parC"
                     /locus_tag="JX887_000741"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAX1256749.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(22402..24447)
                     /gene="parE"
                     /locus_tag="JX887_000742"
     CDS             complement(22402..24447)
                     /gene="parE"
                     /locus_tag="JX887_000742"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAX1256750.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(24613..25047)
                     /locus_tag="JX887_000743"
     CDS             complement(24613..25047)
                     /locus_tag="JX887_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAX1256751.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            25174..25812
                     /gene="plsY"
                     /locus_tag="JX887_000744"
     CDS             25174..25812
                     /gene="plsY"
                     /locus_tag="JX887_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAX1256752.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(25944..26819)
                     /locus_tag="JX887_000745"
     CDS             complement(25944..26819)
                     /locus_tag="JX887_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAX1256753.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(26901..27692)
                     /gene="codY"
                     /locus_tag="JX887_000746"
     CDS             complement(26901..27692)
                     /gene="codY"
                     /locus_tag="JX887_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAX1256754.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(27710..29110)
                     /gene="hslU"
                     /locus_tag="JX887_000747"
     CDS             complement(27710..29110)
                     /gene="hslU"
                     /locus_tag="JX887_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAX1256755.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(29124..29672)
                     /gene="hslV"
                     /locus_tag="JX887_000748"
     CDS             complement(29124..29672)
                     /gene="hslV"
                     /locus_tag="JX887_000748"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAX1256756.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(29709..30614)
                     /gene="xerC"
                     /locus_tag="JX887_000749"
     CDS             complement(29709..30614)
                     /gene="xerC"
                     /locus_tag="JX887_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAX1256757.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(30812..32188)
                     /gene="trmFO"
                     /locus_tag="JX887_000750"
     CDS             complement(30812..32188)
                     /gene="trmFO"
                     /locus_tag="JX887_000750"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAX1256758.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(32157..34235)
                     /gene="topA"
                     /locus_tag="JX887_000751"
     CDS             complement(32157..34235)
                     /gene="topA"
                     /locus_tag="JX887_000751"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAX1256759.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(34357..35214)
                     /gene="dprA"
                     /locus_tag="JX887_000752"
     CDS             complement(34357..35214)
                     /gene="dprA"
                     /locus_tag="JX887_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAX1256760.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(35270..36037)
                     /locus_tag="JX887_000753"
     CDS             complement(35270..36037)
                     /locus_tag="JX887_000753"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAX1256761.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(36030..36890)
                     /gene="ylqF"
                     /locus_tag="JX887_000754"
     CDS             complement(36030..36890)
                     /gene="ylqF"
                     /locus_tag="JX887_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAX1256762.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
BASE COUNT        10126 a         7893 c         6382 g        12855 t
ORIGIN      
        1 aacagaaact gctgctactc cagcaagcac aagctctgca aaagaatgga tcgcacaaaa
       61 agaatcaagc ggttcttaca cagcaacgaa cggacgttac atcggacgtt accaattaga
      121 ttcttcttac ttaaatggtg actactctgc tgcaaaccaa gaaagagtag cagaacaata
      181 tgttacttca cgttatggtt cttgggaagc ggcgaaagca ttctgggaag caaacggttg
      241 gtactaagat tcatttatta atcaaacagt ttacttttat acaaagaaag ccaaaaagag
      301 gtgcgacact agttgtgtca catctctttt ttatttacct aatctaatga aacgttccaa
      361 gttttgataa gtattttttt taacttcttc aactgatagc tctttgatct cagcgattgt
      421 ctttaactgt tcttcaagca gtgagacata atctttttct gaaaaaatcc cccctaaagc
      481 ccactctgct gcatgtagtc catccgtttc aataagtaag tggtcgattg ggactgcttt
      541 agctagttgc cagactgctg gattcttttt caaatcaaga ccaatgctga aataacagcc
      601 taaatcaata tagtcttgtt gatagtccaa agaagaatac caatggatca aatagtgatt
      661 agggtaagct tggatataat ttaagatctc tttttcgcat ccttttgtgt gcagtacaac
      721 aggtttctca tttatggctg caaaagcaag ctgtcgctca aatacttttt tttgtgtagt
      781 catcggtaca ttcgtccaaa tattatctaa ccctatttca ccgatgatcc ttgctttttt
      841 caaaaaaggc tcaacttgtt caaacgtata gctatctgct ttccaaggat ggataccgta
      901 acttaaggct tgagtcttac ttgctgcaag ctgtctgttt tccttccatt cttctggcga
      961 atcacaattg atgatcgtca aaatcgtgtg ttcctgctga aggagtgcta aactctgact
     1021 cccatctaaa tgacaatgag catcacttaa catctaattc acctgccaat aactgataaa
     1081 tcgtttgctt caactctgat tgctgcagta gccattcacg tgaccgtcgt ttttcaggca
     1141 cttgaatctc agcaatcaca tgtgccggac gggcggaaag cacaagaatc ctgtctgata
     1201 aataaattgc ttcttcgata tcatgcgtca caagtaaagt agtccgcttt gcttttttag
     1261 gcagcttcaa catccagtct tgcatctgcc ctctggtcat agcatctaac gctccaaatg
     1321 gttcatcaag aagcaagtaa gaagaaggat tcatgattgt tcgtaacaag gccgttcgct
     1381 gcttcatccc gccagataat tgttccggca aaaaatgttc atagccgttt aacccaaaga
     1441 tatccagata atcccttact tgttcttcat tgattgttag atgattgatt ttttgatata
     1501 acgtaacgtt ttgatagacg ctcagccaag gaagtaacat atcttcttgc ggcatataac
     1561 taaatgctgt atggagacca gttacttttt gatcgtctac tttgatcgtt ccagaagtca
     1621 taggctggac tcctgttaaa gttttcagca atgttgactt accggctccg cttggcgcga
     1681 caatcgatgt aaaggtatct ttagggatag tgaaatggat gtcttctaat attttcaggt
     1741 tttcaatgac tacattcaag tggctgattt ggattgacat atctatcact cctattttat
     1801 aaactgatta gtgaatagtt cttgcgaagg tacatcttgc ttgatcaatc cgttttcctg
     1861 cataaaagct gtataattgc gccaaacttt ttcttccatc aatccccaat tctcaggatc
     1921 atccgtataa ttttttgaca agaatgcttg tgattcttct aaaaacgtcc gatcattttc
     1981 ttttgcatat ttttgcaaca gtttagcact gtcatttgga tccttaatag cttcctgata
     2041 gccttttttc gtggcatcca taaaagactg taccaattct ggatcacttt tgatcagttg
     2101 atcattcgta ataattaccg gagtatagta atctaaccgt tcatctaatt ctttcaatgg
     2161 gatatagttt agttcaatac ccgcttcttt tgctttgatc atatcccaac cttcaaagta
     2221 ccattggata tctgaggatt ttcctaagct ttctggccct tctccattgc ttcctaccat
     2281 tgtcagtttt gaaaagtccc cgccgtcttt ttccatcaca gcttttaaga cagcttcttc
     2341 acttggactt tgccaacctg catatgtttt tccttcaaaa tcttttggtg aatggatgtt
     2401 actgtctgat agggtggcga atccagaagt attatgtttg atcactgtag caattgcttt
     2461 gactggtata ttctgtccat ctgcgtgagc ataagtgaca tcttcttgat aacttacacc
     2521 aaattgtgct ttgtccgcac ctactagacc aatacttgtc gaattatctc ctggttcgat
     2581 gatttggaca tttaaaccag cctctttata atagcctttt tcttttgcta ggtagatgcc
     2641 agtatgatta gtattcggta cataatccaa aacaagtgtc acttttttca aatcctttat
     2701 ttcttgtttg ctacttgttt cttttgcagt gccacaagcg gataaaagca acagtagcgg
     2761 taataaaagc cataattttt tcatttgatc cccttctctt aaaaaatata aagcatacga
     2821 taataccctt ttttcaataa tgaacaagcg ccattcagca ataaactcaa tagaatgaca
     2881 caaatgatcg cagcaaaaac tttatcgatc tggtagctgt tttttacgcg tatcatgtaa
     2941 taccctaagc ctgcttgagc gcttagccat tctccaacga ctgctccgct gacacaataa
     3001 gtagcagcca cttttaaacc ggaaaagaag ccggataaac ccgctggtat tttatatatt
     3061 cgataaatct tccctgtatc tgcccccatc gttttcaaaa agatgatttg ctcttttgat
     3121 actttcctca atgtatccga aaaagaaact acgatcggaa aatagcttat caagacaaca
     3181 aggatcactt ttggaagcat accgaaacca aaccataggg taagtaatgg ccctaacacc
     3241 atgattggca acatttgtga aatcactagt aacggataaa aagacatttc taaaaacttc
     3301 caataatcca ttgccaaggc agtaataaaa gaaagaacgc tagctattac caaaccaagc
     3361 actgcttcat ttaatgtcgt gacagaatgg gaaagtaata cttgtgcatc tgccgctaat
     3421 gcagaaaata cagcagcagg tccgggtaaa ataaaggcag gtattttcca aactatgaca
     3481 acaatctgcc aaataattaa aatgaatgcc atactgactg ctggataaag atttttcttc
     3541 attttgttac ctcctttctt ctaatatgaa taacaaaaaa cgcttgaaat gggcacgaca
     3601 tagtaacccg cttcaagcgt ctgctatgtt tctcccttca ccagtattaa ctgacaggtt
     3661 caatgggtct aagttcacaa cttactctca tgtcgtctac gacatcccca gaaacaggta
     3721 ttcatttttt aaagtgtagc acaagaagga aaaagcaaca agcgctttag ttatcatgct
     3781 gattatttca ataaatagga gagatcactt gccaatgtcg gataccccat gatatagcta
     3841 tccaactctt ttttagtcaa tttttgattg atgacgagtg tcaaatcatc gatcaattcg
     3901 tctgcttgct cgctaatcac tgcagcacca atcaaataat tttgctggtc aaaggtcaat
     3961 tcagccttag caactggttc attgacacga tgataggtga accaactggt aagatccatc
     4021 tctaccactt gatctgacga agaggcgtga ctttttgtaa ctcctacttc agcaagttta
     4081 ggactggcgt agacgatcgt aggtataatc ggatatttga taggttcgct tgttgcatcc
     4141 gttatccgct tagctacata atttccttca aaagtggcga ctggtgtcaa ttttggggtt
     4201 ttccttgaaa caatatctcc acacgcaaaa atttttggat tgctcgtttg cagataatca
     4261 ttgactgcaa ttccgtgttt atcaaagacg atattcgctt gctcaagtgc taaagattct
     4321 gtattcggct gtctcccagt cgcacaaaaa atcatatctg ctactaattc cgtctctttt
     4381 ccgactaaac gatagcgagt accttctgaa atgatctttt gggtttcaac accaaaagca
     4441 aactgaatgc cagatgcttc catttgatgg acggcttcct ctaccaaaga cgcctcaaat
     4501 tcttttaatg gccgttgatt atgatggaca atggttactt tgctccctgc agcattggca
     4561 atcgtagcta gctcaaaagc aatataacca ccaccgataa aaatgatttc tttaggcagt
     4621 acaggcaatg ataaaaagtc tgcactagtt ttcaagtatt cctttccctc cactggtaag
     4681 atcgtaggtc tttgcccggt tgccaaaact aagtaatccg catggaagac ttcttcgttg
     4741 acttcaatag atgaatcatc caaaaaacga gcggttcctg aaagatgatc gatttcagct
     4801 tctgctaatt gtttttttcg gctttctggg actggatccg taaatgttcg tttgaatttt
     4861 tgaagttctt cccagttggc agttgggatc tcgttaaaac cttttccact caattgtttt
     4921 acccgattac gtgcctctac tgcacttaac aagacttttt taggatcaca tccacggtta
     4981 ggacaagtcc cgccccatag atcttcttcg accactagta ctgttttacc tgcttctttc
     5041 aatccataag cagcacttaa gccgctcaca cctgaaccga tgatgattgc atcatatgtt
     5101 ttcatttcct tcctcctctc gacttaaaaa agcaaagatt tctttacttg tcagcgaccc
     5161 aatacttctt tgcttttcta ctatcacaat gcttggatac accgaaagaa gcgaatatac
     5221 ttctttcata ggcgtatcaa agcaaacttg ttgacgagca ttttctggta tttcatttaa
     5281 gaaatatcca ttgacgacta aatcttctac tcgccactct ttcgtctgtt tcggttcatc
     5341 aaagaaatgc cgaacgtagt cgtttttagg attcatcaat aactgctctg gtgtgtcaca
     5401 ttggataatt tctccatcct tcataaatgc aatacgatca cctagcttga ttgcttcttc
     5461 catattgtgc gtaacgaaaa cgatggtcgt gcccaattct tcgtgtaagg acaaaaccaa
     5521 ttcttgtaat gagtttcttg aaatcggatc taatgcgcta aatggctcgt ccatcaaaat
     5581 cacatctggg cttgcagcaa tagctcggat gatcccgatc cgttgctgtt ctcctccaga
     5641 caactctcta ggcatacgat ctcgataaat atcaggagat aagccaactt tttgaagaag
     5701 ttcatctaca cggtctgctc ttttctgctt ttcccaacct aacatttcag ggatgacttc
     5761 aatattttgc ttgactgtca tggtcgggaa caaagcgatt tgctgcagca catatcccat
     5821 attccaccgc attttctgca gattatattc atttaacgat tttcctttga agtagatgtc
     5881 tcctgctgat ggtttagata atccattgat cattttcaaa gtagttgttt ttccactacc
     5941 ggaaggacca accaaaacaa agatttctcc ttttttgatt gccagattta ggtcatcgat
     6001 gacatacttt ccatcatact ttttttgcac atgtttgaac tcgattaatt tagtcactga
     6061 tcttcctcct ttactaatcc ttcatttttc aggaagattc gtgctacttc tgtcggcttt
     6121 ttcttttcga cattgacttg gtaattcata tcaatcattt gatcctctgt tatttttccg
     6181 cttaatttat tcagtgcttt aacgatttca ggatgttctt tagcaaaatc ttttttcatc
     6241 agcggtgcgc cttgataagc tgggaataac cctcgatcat cttctagagt cactagatcg
     6301 tactccttga gctggctatc tgtggaatag gcatccacaa tattgacatc tccattattg
     6361 attgcttggt aacgcaaact tggctccatg ctttgtacac ttgaaaaatt caagccatat
     6421 gcttcttgga ttcctttata tccatctgaa cgatcaataa attccagtgt gaatcccgct
     6481 ttgatctgat cagagatagc tgccaaatcg gaaatctttt taagttgatg ttcgttcgca
     6541 aaagatctct tgactgccaa ggcatacgta ttttggtaag ccattggttt taataatgtc
     6601 atatcgaatt gcttattcaa taattcttct gcttcgtcat atgttttttc ttttgtcaaa
     6661 tcagcacttt tcattgcttc aggtaccttc accaagcttt ctaggacagt acctgtgaac
     6721 tcaggataga tatcgatttg accttgatcc agtgcattga acaaaaaact cgtcttgcca
     6781 aaattcggtt ttaattcaac ttctgttttt gtgttgtctt caatcaattc tttatacatt
     6841 tggatcagga tttcaggttc cgctcctaat tttccagcaa tcgtgatggt ttcattttta
     6901 aacaaggcag actgatataa agaaacgccg ccaaataaac acaccactgc tgctaaagta
     6961 atgatggaat atcgaggttt cttatgctgc aaccagcgaa tcagtccgct gaatataatt
     7021 gcaagcaagg cagaactgat cgcaccaatc aatgtcaaaa caggtgtatt tcggtcaata
     7081 cctaacaaaa taaatgtccc taatccacct gctccgatca atgctgccaa agtagccgta
     7141 ccgatgatta aaactaaggc agttcggata cctgagataa tgacaggtaa tgcgatggga
     7201 agctctactt tcagcaagcg tctcattctg gacataccaa atgctaccgc tgcttcttca
     7261 atagacgggt caatttcagc tagaccaata tacgtgtttt ggaaaatcgg aagcaaagcg
     7321 taaataacaa gtgcaatcaa tgctggaaca gttccgatcc ctacaaatgg gataagtaaa
     7381 cctaataagg caagtgaagg aatcgtttgg agcacacccg tgatctgcaa taagacttct
     7441 gccatttttt tatgattggc tgcccaaatc gctaaaggaa tagcaatcag tgctgcaatc
     7501 agcaaagaaa tgagagaaat ggacagatgt tgaaatgcag cttccagcaa ctcgcctttt
     7561 ctttcactta atgtttgtat aaaattattc atgcgacctt cctttctgtt attctttaag
     7621 tataaacatt tctttccttt ttcccaacta acttgtcttg ccttaacctt acagcacgaa
     7681 caaaaaaaag aaaaaaatac ctctaaatat gctgacaaaa aaagaatcca agcaacaaag
     7741 tcggatcaac tttttggttc tcgttttttc actacgaata ccataaaaat ctatacgaaa
     7801 ttgtcacttg gaatcagcta tatctttttt acacacacaa cttttatttt aataaaaaga
     7861 aacagccaat aaagtagaaa tctcgtgggg gagaacacct ttattggcct gttcaacgaa
     7921 tattatactg tatcatgaca cttttttgcc aaaaatgtaa aaaatggttg ttttgacatc
     7981 ataaacgtct tgttttctta tttttactta tatcaccact ttattttcta tctctttcac
     8041 tccataaaga ggaatgagtt cttcttttga ctgataataa acagctttct cacggttctt
     8101 catcaaaaaa agaaagatgt ctttcatagc aagtggtgct ttgccgtgtt caaataaaaa
     8161 gataaattga tttgctttat ttatctggac cattgtcaca ggcaccagtt tttgttcttg
     8221 agccaaaaaa actccttgat actctgtttt tttgggtgat tttgtaagaa ttgtcaataa
     8281 gtctgctgct cgcatttttc cactccttat ttgataaata aaaagaaaca gccaaaaata
     8341 attttttttc attttcctct tgaagtaaga gtataagtca gtataataaa gaagttgctg
     8401 aaaattttca aaagaaaaga ggctagaaat gaaaaaatta aatttattta cagaattgtg
     8461 cggaatcatt ttaggcgcag gaatctacgg attagctgtg acaggaatca atattccatc
     8521 taagctggca gatggtgggg ttactggtat tgctttgctt ttgcataatc tttttggatt
     8581 cgctccttct gtcacttcac tgctttttaa tttaccttta ttgcttatct cattgtttct
     8641 ttttggaaaa cacgcttttc tccggacgat cgtcggaaca tttgcgctag ttttcttttt
     8701 acatttatgg gagagccttc atatacattt tgctgtagat agtctactga tcaatagttt
     8761 gatgacaggt attctttctg gcattggttg cggtctcgtc tttcgattcg gcggaagcac
     8821 aggcggaaca gatatcattt atcaagccat tgaaaaatat tttcatatta agattggcaa
     8881 aagtcttttc ttgattactt ttggtatttt agttgtctcc ttgctttatt tggatctcac
     8941 acattttctg tatacattac ttagctgttc tattctatct tatacattga ataaagtgaa
     9001 gtatctggaa attggatctg ttttgcccca attggaagca aaacagacta cagaaacatt
     9061 tgaaccactt gatcctcttg aacagttaga gcactgattc ttatttttca ctactttatt
     9121 taatttacag aaatatcatt atgtaaacta aaatgatatt attcagtaaa atcttcttta
     9181 taaaaaaata aactattttt gcaaacgatc tgcgaaaata gtttgttttt ttattttgcc
     9241 attattttct tacttattgg gagaaaaaat tcgcttaaac tcaaaaaaat ttgaggatac
     9301 gatataaact ttcggataga gtataaaata aggaaacgcc gcagcgtttc ctttccaact
     9361 gtagccgaat ataaatttgt atatcactta tttaaaatag ctattttctc ccaaagagtt
     9421 tccttgatca tcgatcaatc cttgtaatga gcgttctaag ataccatggc tttttttcga
     9481 ttttttttct tctgactgct ttgtttcctc taacgttttt gttcgattga atgttcgtac
     9541 agacggctca ccatttcttt tttcttgata cggcgtcggt tctgtatcga acaacagata
     9601 agagtcatcc gtttttttca tcgattcgat taaatgatcc tcagaaattt tgctttctct
     9661 agggtctggg ataatcgatg cgggtacata tttaggaaca aaataagaac gctcccgcac
     9721 cttcgtgtca acagatgcgt ttcgtgtagt atgcttggac tctgtccttg tttcactttg
     9781 tctgacagaa cgagaggaat caccaaaaag tttttttcgt cctgtcgatg tgatttctga
     9841 ttggtaatgg ccggtataat ccggtaattt tcctttatgc ttttccaaat tttccttacg
     9901 cggagctgac ttcaatccat ttgttgcacg acgcttgcga cggattttct cggtgttcgt
     9961 gttcgtgaaa tgaaattctt tcatctgttc aaacggggac tgattctgtt cagtcaaaag
    10021 atcttcttgt ccgtcaaata atactcgctt cttgtcgttg gttaatttta cgcctaactc
    10081 atcatcgtac gcaggaaaac ggaaatgttt tcgtctgatt tctttcattc aaaccatcct
    10141 tctcaaaaat ggaacttttc tcaataatag cacagattca ttgttttcag tagcaatgcg
    10201 ctgattattt taagaaaata gcgatgaatt tcataaatat atatatagta ataagactta
    10261 attcgttgtc tctctgataa ctagttcagg aaaaaaacga cgataacctt gactcgcccc
    10321 tttttcttct atttttttta acaacatttc tccacatact tcacccatac gtataatatc
    10381 ttgcttgatc gttgtcaatt taggtgaact gatttggtct aaaaataccc catcaaatcc
    10441 aatcacacca aattcttcgg gcaagtgtcc tccagcattt ataatccctc ttactgctcc
    10501 tagtgctagc cgatctgaac tacatacaaa acaagtttta tctgtaaaat ctgcccagtt
    10561 ttctgtcata tatctttcta cttctgtcga atgatttgga aaccgcaaga ttttactagg
    10621 aagatcaact tccttcatca cagataaata accagtttcc cttgaaattt caaaaggctc
    10681 gtccacttcg ataccgatat aaataatcgt ttgataatct ctttctaagg catattgcgt
    10741 tgcttttgct gtaccatatt cattatcgct gtctacataa tcatatcctt cagaattttc
    10801 cccaaacaag acaactggtt tttccaaacg gtcgatccaa tcgaagtctt tttttctgac
    10861 acctgtgatg atgtatccat cacaagaacc gacgtcgaag gcatcatttg taactaattg
    10921 gagagaataa tgcgctttac cgatccgttt agcgattccc atcagcaaat tcatgtaata
    10981 gggctcagtt gtgtcgattt cttccagtat aaataatttg atgatctgcg accgattcgt
    11041 gacaagtgct tttgcagcaa tatttggacg gtaatccagt tcagccattg ctgagaaaac
    11101 taactctttc aattcgtcag tcacctgttc cggatgattg atgactcgag agaccgtcat
    11161 ttttgaaaca ttggcacgtt ttgcaacatc tgctaaagtg ggcatgctct cttcctttct
    11221 aacatgttgt cattcttact atcaattata ccaaattttc ctaacagagt ttattatagc
    11281 ccaaaataaa aaacggaaaa tcctctatcg tcatgagtga ttttccgttt caattattta
    11341 tactttttta tcaaattttt tgctaaaaaa gtggaagctt cttccattag tggtatttgt
    11401 accatatgtc gctgtgtttt tgaggaacga aaaacaattt cttttccgta agacttatgc
    11461 cgattttttt ctacaaatcg ttccgtttgt atataaggga ttttttcgtc agcttgtcca
    11521 tgccaaaaga acagaggacg tccagctaac ttttccggct gcaatgacaa atcatagctc
    11581 ttaacccatg aaatcaaatc aaaatagtct tttggtacga cataattata ttccgatgcg
    11641 cgccttacga tttcttttcc atattccaaa ggtgcagggg aacccatcaa acacacgccc
    11701 gctactatat gaggatgttt agccaacaag gcgcatgttg tcattccccc catcgaaacc
    11761 ccgccaactg caagctgatc atgtagaaga cctctttttt ctaaatgctt gataagtgtg
    11821 tcaaattcaa acagatttcc gtagatacta tcccaaaatg tataggatgg aatagaagaa
    11881 accggctgtt tgcgctcccc atgattcatc gcatctggca ggatcacacg aatgccctgc
    11941 tgcgcaattt ttcttccttg cgtcaaaact aactccttac ttgtctgcca tccgtgataa
    12001 tagatgacaa cgggaatacg ttcctctctt aattctttca gaacaacttc taacactgga
    12061 atatgatgga cagaacgttt caatataatt ggattcaatt gttactcacc tattttcatt
    12121 aaatttcctg atcgccatag caaccatgct ccaacagttg tctggaacag gttcagtgta
    12181 ccaaataata taaatgcagg actgaatggc tcgggaaata agcacagaga acaaagtccc
    12241 accactccta atgctagcga aaggagtgga taaatagaaa aattcaaaaa actggcaacg
    12301 ctaccgaaaa tattaccaat aaacagtatc aaaaagaaaa aaacgcttaa aattaaacca
    12361 tctgtcagcg acatctgaaa aacaatgttc tctacctcaa ttggctgttg aatcgaatag
    12421 acacctaagt atatactgag aaggagactt agcacgtggc tggcacaaaa cacacgattg
    12481 accgttttca ttttaatcac ctaacctatc tttataattc tattataatc attttatcat
    12541 ttttttgtat gtataaagtt tcaatttttc ttcacttacg attttttttg atattgttgt
    12601 tatataaatg aaaggagttt tacaaatgat tgatccaaaa atgttgggga tgatcttcct
    12661 cattaatttt gcttatatca ctctgaacac gttacgtttc atgttgacaa tgaaaggcta
    12721 tcgactgatt gctccacttg tcagtatggt cgagatcacg atttatatcg tcggcttatc
    12781 ccttgtttta gatcgtttag ataatccact gaatttattt gtctatgcgt taggttacgc
    12841 agtaggtatc agtgtcggaa ttttgattga agacaaattg gcattaggat acatcatggt
    12901 cacaacgatt ttgccagcaa atagcgcaga agataaaagt ttgccgggta tactgagaga
    12961 acacggttat ggtgtgacac agacttctgc aatggggctg gaaggtgagc ggctagttct
    13021 cgaaatactt tctcctagaa aaagcgaacg tgaactgtat cgcctgatca aagaaatcga
    13081 agagcgtgct tttatcattt cttatgagcc aaaatatatt tcaggtggtt tctggactaa
    13141 aaaagtgaga aaacgacaag gaaaataact cacaaactta aaaactgtct aatatctaaa
    13201 ttaaatttta aatgttagac agtttttatt tattattttg attaaaaaac atcgacatat
    13261 actcatcaat ttgttattat actttatata cttatcaatt taatttggag atattatgga
    13321 aattcaacgt agaaccacta attttttaca tttaggctct ttttttgcaa ctttgacgat
    13381 cttatttttt ctatgttatt cataccttaa gacctcacat gcgccttcta gtgcattagg
    13441 ctggttgctt ttggatcatt ctgatatcac agaagccgaa gaaaatccgt tttttttgat
    13501 tttgtcttct ctttgcggct tactgttttc tgtttatttc ggtgcctatt tttttcatcg
    13561 acatcctggt acgttaaacg aagcttcaag cgtattgatt gcatttaaaa cgttttcttt
    13621 tttagcaatt cttttttatt cgtttaatca caatacgctt ttcttcttta tcatgaatgg
    13681 tttagtcgtg attttatcca tttttactta ttttattttt tcactcattt ttagccaatt
    13741 gaaatgtccg ctcttctttc gattagttcc tgtcacctgt tttatttaca gcttgttttc
    13801 cttttttgtc cttgctttaa tgccactgac caacccttcg acgatccaag tcgcaggaaa
    13861 tctgttggat atgctcttca tcgtcagtct aggtgtattt atgtggcaaa gaaaaaacaa
    13921 acaaaataaa aagcattttg aagcctgact attacgactt cataaatgct tttttagttt
    13981 taaacacttc aatctaaaag aataacccaa gattggataa attattaatg actcgccatt
    14041 cgtttcttag tgattctgga ttatcaaatg gacttcctaa tctaatcagc tagttcttcc
    14101 cataaaatgc catacttgac tgaatcataa tattgattat ttaaaaatct aacttttctt
    14161 atcactactt cctttgtcat tccacatttc tcaccatttt tttgcattcc tttgtttcca
    14221 gaccatgtag tgaatctaat aggtggtaga taggcaaaat actcaaataa ttcttttaac
    14281 cataaaggaa gagaaaggct cctcctgcaa gagtcagtat aatttttgct tactgctctc
    14341 ttaggtttta ctcactaaaa ctgttccata ttctttgata taagaaaatg catgcggtat
    14401 aaatttcttg ctcagctcag aaaagatttg tcgtttaaga aaggccattt cctccattgt
    14461 caatgaagga tccaatgttg gtaattcaat ctcaaaattg tttttttcga caataggtaa
    14521 ttctaatgtg aatgattctt cttcctttat agtattcgtc acaagtagag actgatggaa
    14581 aatactaggc cggcgatttt tatatttatt cttacgtatc ctgtcaacga taacttctat
    14641 ttgatcaaaa aagtacgatt catttacgtc tccaataagt tcggctaatt ctttgaatgc
    14701 cttcgttaca ggaagctgat tcttctgtac aaaaaagtaa ttagccaaag taagcgggaa
    14761 gtgttctata gaggaaagtg tgataaaacg gtacttctca tttcctgcag ttgtcctcag
    14821 caattctgtc tctcggctgt ttcttactcc ataaaaatac gcttctttcc gttcatcttc
    14881 gaaacaatac gcccaaataa cttctcccat cgctaatttt tgttcatcaa cagagagtct
    14941 cttcaattgt tcagctatgg tttcagcagc cgaagtggct tgttgcaagt aatctttagg
    15001 atcaaatatt ggaaagttca aatgatatct tcgttcttcc ctcttgatta atcctgcatc
    15061 gatcaataaa tcaagaaaat gggaaaattt attttgcgaa aattcttttt tcaattctct
    15121 tagaatcgtt tcttgttctc gatgttcata tagataatcg gtcaatgaag aaaaaagcgg
    15181 atcatcggtc agtttttgat aaaagttttc cttatttttt gaataatagt tcatatatgt
    15241 tctcttttct atccgtttta ttttacttaa aaggctttta cgtaaaaagg aggaagaaca
    15301 agagtcataa ttgactgtta ttctcctcca tttcttcggc ctttagtatg ttctatgttt
    15361 ctttttatat caatcgctta tccattcatt ttgaatgctt catactacca tttgattagc
    15421 taaatacagc cgtcaattga ggtacgactt gttttttacg tgaaacgaca cctttaagca
    15481 aagcacggtt gttggtcaaa gttgtttgga aagcttcttc tactttttct tttcctttac
    15541 cagcaacaag taattctgaa tcactgtcta agatgtttgt gacaactaat acgaacagat
    15601 cgtagccatt tgctttcatt tcatcttcca ttgctgcttc tagctctgct tgtcgatcca
    15661 tcacttcatt aaggtccact gtattgactt gagcgatacg aacgttggaa ctgcccattg
    15721 ggaaactttt tgcatccaaa tcaagaagaa ccgcagctga tttatcactt agatttgttc
    15781 ctgctttcaa catttcaagt ccataagtgt ttagatcgac ttcagcgatt gctgcaagtt
    15841 cttttgcagc tgcttcatct tcaggcgtac atgttggtga tttgaacaac aatgtatctg
    15901 aaatgatagc tgagagcatg attcctgcga tttctttagg aattgttact tggttttctt
    15961 tatatagttt taaaataatc gtacttgtac atccaactgg ttctgcacga tagtacaatg
    16021 gattagctgt ttcaaagttt gcaatacgat ggtggtctac tacagctaaa atatttactt
    16081 cgctgatatc tgaaatactt tgttggaatt cattatgatc cacaagcatg acatctgcat
    16141 tttctgcttt agctgactct actactcgtg gtgcagatag ctgaaagtgg tctaatgcgt
    16201 attgtgtttc ttcattaggt gtacctagag caactgcttc tgtttcttta cctaattcat
    16261 tttgcaagtg tgaaaacgca atggctgccc cgattgcatc tgtatctgga ttttggtgac
    16321 caaaaactaa aatttttgac atgtcattcg ctcctttgtg atttctccta tttaataata
    16381 gcaaaaaaac ggaaagaagc aatacttatc ttctttccga tgcgacctat cgcgttaaat
    16441 attttgtata ctcttctgta tgaagcaatc gtttagcatt ttcgacacgt tcttttgtag
    16501 gtggttcgat cccttctaat ggatatttca aaccaagtgt ttcccacttg tattttccca
    16561 tcgtatgata aggaagaatc tctactctgt ctacatttga caaggtttga ataaagttgt
    16621 ctagtcggat caaatattca tcataatcac ttcgctcagg aactagtaca tggcgaatcc
    16681 aaaccggttt gttgattttt gacaaatatt gagccatttc taaaatattt tcattgtccc
    16741 aatgcgttag ttttttatgc tcttcattat cgatgtgttt gatgtcaaat aacagtaaat
    16801 ctgtatactt catcaattct tgaaaacgtg aaaagaaagg ttcttcatac gtaaaaggtt
    16861 ttccgcatgt atccaatgta gtatgcatct tccgctcttt tgctttttta aatagttcga
    16921 tcaaaaaatc gatctgcaat agaggttctc caccactaac agtaatacca cctttatctc
    16981 cccagtaagg tctgaagcgt tctgctttat ctaaaagttc atctgctgtg tattctttcc
    17041 ctccgccaat attccaagta tctggattgt gacaaaattg gcaacgcatg cggcatcctt
    17101 gcataaacac gacaaagcgc agtccaggtc cgtctactga accgaaagtt tcgatagaat
    17161 gaacatagcc gattgttttt tcttccattt aagttcacat cttttctttg atttcatttt
    17221 aagtacaagt tagctgtcga agcgaagctt tctgaacaaa atttttcgca attgccgctt
    17281 cgttatgtgt aaaatttaca gggacggaac atacaagtcc tgcccctgta aatcgtttct
    17341 ttcaaataag catactgatt attcgatttt gatgcgatgg ctattcaacg tcctttcgac
    17401 gctaagtcga aaaacttttt tcacgaactt tttacattct gtcgtgtgaa gttctcatca
    17461 agacatctaa ttgttgttct cttgtcaagt cacggaattt aactgcataa ccagataccc
    17521 ggatcgtcaa gttcggatat ttcattggat tttccattgc atcacgcaat aaatcattac
    17581 tgaatacatt gacattcaaa tgataagctc cttttgagaa gtatccatct aagacattac
    17641 gcaagttttc gattcttgta tcttgttctt ttccaagacc tgaaggattg attgtttggg
    17701 tatttgaaat tccatccaat gcacagccgt aattcatttt agctgttgag ttcaggctag
    17761 ctaataaccc actttgttcc gcattgtaac ttggatttgc tcctggcgca agtggttttc
    17821 cagcttcacg gccatcagga gtatttcctg tatttttacc gtaaacaaca tttgaagtaa
    17881 tcgtcaataa tgaagttgtt ggttttgagt tgcggtaagt tttatgacgt ttgatttgtc
    17941 ccatgaagta ttccaagatc catgaaacta attcatctgc acggtcatca tcatttccgt
    18001 atttagggaa gtcgccatcc acttcaaaat caactgctat tcctttttca ttacggattg
    18061 cttttacttt tgcatatttg atcgctgaca agctgtctgc cgcatgagag atcccagcaa
    18121 tacctgtagc aaatgtgcgt tgcaagtcag aatccatcaa agccagctga gctgcttcat
    18181 aagaatattt atcatgcata taatgaatga tgttcaacgt attgacatat agttctgcta
    18241 accaatccat catattcatg aagttatgtt tcacttcttc aaagtctagt atttctgatg
    18301 tgattggacg atattctggt ccaacttggg cgccagtcac ttcatcgact ccgccattga
    18361 tggcatataa tagtgtttta gccaagttag cacgagcgcc aaagaattgc atgtcttttc
    18421 cgacaactgt tcctgataca cagcaagcaa tcgcacaatc atcagaaccc cattgttcac
    18481 gaagctgatt atcattttcg aattgaatcg aagaactttc gatagcgatt ctgctagcat
    18541 atgttctgaa tccttctgga aggtgttcag aatacaaaac agtcaagttt ggttctggtg
    18601 aaggtcccat atttgttaat gtatgaagca gacggaaatc attctttgta actaatgaac
    18661 gaccatctaa tcccatacct gcaatggata aagtagccca gatagggaat cctgagaata
    18721 attggttata ttcaggtgta cgcgcgaatt tgaccatacg taatttcatt actaagtggt
    18781 cgatcaattc ttgtgcttct ttttctgtga ttactccatt atccaaatca cgttggatat
    18841 agatatcaag gaatgctgag atacgtccga ttgacatcgc agcaccattt tgtgatttga
    18901 ttgctgctaa atatccgaag tatagccatt ggacagcttc ttttgcattt gcagctggtt
    18961 tagaaatatc atagccatat ttcgcagcca tttctttcat ttgcgctaat gcacgatatt
    19021 gttcagtgat ttcttcacgt aaacgaatca cttcttcact cattgtatga taaccagtca
    19081 tatcatgatc ttttttcttt tgttccatca aatagtcgat tccatacaat gccacacgac
    19141 gatagtcacc gatgatacgt ccgcgaccgt aagcgtctgg aagccctgta atgattttgt
    19201 ttttacgagc agcacgcatt tcagcagtat aagcgtcaaa tacaccttga ttatgtgttt
    19261 tgcgccagtc agtgaaaata tgtgtcaatt catcgtttgg tgtatagcca ttgcttttta
    19321 gcgcattgtt agccatattg attccgccga acggcatgaa tgcttgtttc aaaggtttgt
    19381 ctgtctgtag accgacgatt ttttccaaat ctttatccaa atagcctgca tcgtgtgaag
    19441 taatagttga tacgatttct gtgtccatat catagacacc gttacgctcg aattggatat
    19501 catttaactt ttgcaattca tcccataatt tttctgttgc ttctgttggg ccttccaaaa
    19561 agctgtcatc accgcgatat tcagtgtagt tattttgaat aaagtctcta gtgtctacgc
    19621 cttctttcca tttggtacct ttaaatccat tccattgctc cattgtatgg acctcctaaa
    19681 tttctgtttt atgtaacagt ttttacgtga ttagtataac acagcaccct atctttgcaa
    19741 gggttttctt gttttttatt taacaatttt tatgttttat ttacatatat ttaaatcaac
    19801 gttgacatac caacatttaa gcattgtgaa cactttcatc tttttttgca aacgtataag
    19861 gatttattaa aaatgaatga aaaagagacg ccacctgtat taatacagat ggcgtctctt
    19921 cattaaaata ctacaacagt tacgactcga tgaaaatctc aggagcatcg ataacttcga
    19981 tgacttctcc accttttttc tcatccatcg caaatgatcc attcgatgtt cgatcaccta
    20041 tagggaaatc agttgggtca atcgttaact gctgcccttt ttgattcatc aaggttattt
    20101 cttttgatct tccttccgac atatagataa tacggtgcgg attttttttc agctcacgca
    20161 tgaccgtcac tccccgcttc gcacgtgaag tttggctgat ttcttgagca agcatgcgtt
    20221 taacagctcc tcgctgagta acgattacga tcggcgtatc accttctgct aacacaagca
    20281 gcccgttgat aatcctatct ccatctttca aattcataga cttcactcca gctgcctttg
    20341 ctccaacaac gggaacatct gttaaaggat agcgcaaacc cattccttga tgcgttacta
    20401 agaaaacatc taagcctggc tgatcttctt tcagatacac agcaatcagt tcatcttctt
    20461 ccgcctttag cttcatacag ctgagcggac ggctcttata ggtgcgccat ggttcgaact
    20521 ctgtcattcg tgtttgcttg atcaatccat tcttgctgat gaatacaaat gttttctctg
    20581 cttgaatttt ttgatatggg aaaacagcta aaatcgattc gtctacagac agattggaga
    20641 ttgtttgaga aatgtgctca ccagcatctt tccatttcaa atcgggtagt tcatggacag
    20701 ggcggtagat cacatttgct ttatttgtga tcagaagaac atggtccaat gtactcaatt
    20761 cacctgagta tagcaagtag tcgccttctc gcatcccgat ttcttctggt ttggaagcac
    20821 tataagaacg aaggcttgtt cgcttcacat agccttctcg cgtcacactg acaattacgt
    20881 cttcttgtgc cactaagact tgcgtatcaa ttttgatttc ttcgatttcg tcttcgattg
    20941 tcgttagacg agcggaagaa taattttttt tcacttctcg caattctttt ttcataacag
    21001 agaaaagctc tttgtcattt gaaaggattt tattcaactc tgtgatttgc gcaatcaagc
    21061 tttcggattc cttttgaagc tctgtgatat ccgtgttcgt caaacggtat aattgcaatg
    21121 tgacaattgc ttctgcttgt tcttctgtaa attgaaagac gtcgactaaa ttctttttgg
    21181 cgtctttttt gtctttactt tcacgaatcg ttgcgattac ttcatccaga atcgataaag
    21241 ctttcatcaa tccttctacg atatgctgtc ttttttgagc tttggctaaa tcgaattgac
    21301 tacgttttgt tatgacttgc tttcgatgct cgatataact tcttaaaatg tctttcagtc
    21361 caacttgatg cggagtcata tggtcgatag cgaccatatt gaaattgtaa ttgatctgta
    21421 gctcagtgtt tttgaacaaa taattcaaaa ttccttgagc attggcgtct tttttcaatt
    21481 cgacgacaat ttgcagacct gttctatcac tttcatctcg tacttcagct attccatcga
    21541 ttttcttatt caaacggatc tcatccattt ttttcaccaa ggtcgcttta tttacttcat
    21601 atgggatttc tgtgatcacg atttgctgtt tattaccctt cattgcctct atctttgttt
    21661 tcgaacgaag aataactttt cctcgtcctg tttcataagc ttttttgatt tcatcttttc
    21721 cttgcaagat ccctcctgtt ggaaagtcag gtccaggaat atattccatc aatttttcaa
    21781 ggctcgcttg tggatgatcg atcatataga ttgtgccatc gatcacttca gctaagttat
    21841 gagtcgggat ttctgttgca tatccagcag atatacctgt cgatccattg acgagaaggt
    21901 ttgggtatcg agctggaagg actgttggtt ctttttctgt atcatcaaaa ttccacacga
    21961 gatcgactgt ttctttctcg atatctgcta gcatctctcc acttaacttg gataatctgg
    22021 cttcagtata acgcatcgca gcaggtggat caccgtccat actcccgtta ttcccgtgca
    22081 tttcgatcag tacttcccgc aacttccagt cttggctcat gcggaccatc gcttcataaa
    22141 tactgatgtc accatgagga tgataattcc ccatgatatt tccgacagat tttgctgatt
    22201 tacggaatcc tttgtcatac gtattgccat ctttgttcat ggcaaataat atccggcgtt
    22261 gcactggctt caatccatca cggatatcag gcagtgcacg ttcttggata atatatttgg
    22321 aataacgtcc gaagcggtca cccatcactt cttctaaagt taattcttgt acttcttgtc
    22381 gattttccat caggtgacct cctattctac ttcaaataac tgattgtttt catttttatc
    22441 tgctcgttct tcatctaata aatcattaga aactgaagga gagatttcag tatcctcttt
    22501 tttatctaag atactgccat cttcttcgag cgtaaattgc acgtgatttt cgatccattt
    22561 tcttcgaggt tctactttgt cacccatcag tgtggttact cgacgttcag cttgcgcagc
    22621 atcatcgata cggacgcgga tcaacgtacg ggaagtcgga tccatcgttg tttcccacaa
    22681 ttgttccgca ttcatctctc caagtccttt atatcgctgc agcatatatc ctttgccgac
    22741 ttttttaatc attgctgcca attcgtcatc tgtccacgca tattcaatga cttgcttctt
    22801 tccttgtcct ttggatactt tatataaagg cggtaacgcg atatatactt tcccagcttc
    22861 aatcagcggt ttcatataac gataaaagaa agtaagcagt aatacttgaa tatgggcgcc
    22921 gtctgtatcc gcatcggtca tgatgattac tttgtcgtaa ttacagtctt cgatagaaaa
    22981 ctcaggaccg actcctgcac caatcgtata gatcatcgta ttgatttctt catttttcaa
    23041 gatatcttgc attttagctt tttcggtatt gatgactttt cctcgtaaag gtagaattgc
    23101 ttggaacttt ctgtctcttc cttgtttagc agatccgcca gcagaatccc cttcgactaa
    23161 atacaattca tttttcttag ggtttcggga ttgtgcgggt gtcaattttc ctgaaagaag
    23221 agattcgcct tttttacgct tcttcccatt tcggctttct tctctggctt tacgtgctgc
    23281 ttctctcgct tctctggctt tgattgcttt acggaccaac atctggctca tttcgctatt
    23341 ttcctgcaaa taaaagccca tttgttcact gatgacgtta tctactacgg tacgagcaac
    23401 tggcgtacca agtttttctt ttgtttgccc ttcaaattgc agaagatttt caggtacacg
    23461 gatagaaagt acagcagcta acccttctct gaaatcacta ccttccagat tcttgtcccg
    23521 ttctttcagc aaaccaactt ttctcgcata ttcattataa gatttcgtca tcgccgcttt
    23581 cataccagct tcatgggttc ccccatcttt tgtccgaacg ttattgacaa aagataaaac
    23641 attttctgaa taaccgtcat tgtattgata agcgacctct acttcgatac cttctttttc
    23701 tcctgaaaaa taaacaactg gtgtcaatgt atctttttct tcattcagat aatcaacaaa
    23761 ttctttgatt ccttcttcgt aatgaaaaat ttccttgact ggttcttctc cacgaagatc
    23821 agaaagagag attttaacgc cttttagaag aaaggcagat tctcttaacc gttcggctaa
    23881 aatttcatat gaaaatttcg ttgtactgaa tattgtatca tctggtaaaa aatggacagt
    23941 cgtcccgttt gctttttttg tttttcctat ctttttcaaa gtaccgtcag gtttaccgcc
    24001 gtttttaaat ttctgctgat actctacgcc atctctaacg atcgttacaa ttagccattt
    24061 cgataaggca tttaccacac tggctcctac accgtgcagt ccaccagaag ttttgtaccc
    24121 tccttgacca aactttccgc cagcatgcag cacagtaaaa atcacttcaa ctgttggtat
    24181 tccggaagca tgcattccta caggcatccc acgtccgcta tctgcaacag ttatactatt
    24241 gtcttcatgg atggtcacat caatctcact gccataacct gataatgctt cgtcaactgc
    24301 attatcgacg atttcataga ctaaatgatg caagcctcgg ctgtcagtgg atccaatgta
    24361 catccctggt ctttttctaa ctgcctctaa tccttccaat acttggatgg acgagtcatt
    24421 gtattcgttg tttacttttt ttgccaaggc aaacgctcct tcaataatac tttgcggcaa
    24481 aaccgcacca cgattatcat actagaaaag gtcgtgaaaa aaaagagggt agacgagaaa
    24541 tcaattttaa ttatctccta accgcttttt cgacattccc ctctatcgat catctcttct
    24601 ttgtggtcat ttttattttt ggttttcttt caacttacca agttcaatct taatacaacg
    24661 atccattacg atatctgtac gtcctgcttt tcttagcatc tcagctgctt ctttgttttc
    24721 aatccctaat tgtgcccaga acactttagc atcagttttc aaaaaatcac ctgctatttc
    24781 aggtaaaaat tcactccgtc taaatacatc tacgatatcg attggatcat cgatttctgt
    24841 caaattcgca tagactttct cgcctagaat ttcttcacca gccaataatg gatttactgg
    24901 tatgatttta tatccattgt cttgcaatac ctgtgcaacc atgtaacttg ttcgttctgg
    24961 tttattgctc aagcctacga cggcaatatt ttttgcttct tccaaatagt tgaaaatcgt
    25021 ttcttgtgtt ggatttttta cagacatttc tgccacccct tgcttttctt tttattccat
    25081 ctattatact tgtatctttc attttttcaa ttgttcctgt tacctattca tgctaaaata
    25141 aaggatagtt ttcaacttga aagagggtaa aaaatgaaat tgatcttatt acttatttta
    25201 gcatatcttt taggttctat tccttccggt gtctggattg gcaaattgtt tttcaaaaaa
    25261 gatatccgac aacacgggag cggtaatact ggaacgacca atacatttcg tgtattaggc
    25321 aaaacagccg ggattgttgt cctgcttatg gatattttaa aaggtacatt ggctacttgt
    25381 ttgccgatga tcttccacct ttctgggatt aaccctcttt ggtttggggt atgcgccatt
    25441 cttggccata catttccgat ttttgctggg ttcaaaggag gaaaagctgt tgcgacaagt
    25501 gcaggaatgc ttttaggatt taatcctgta ttttttgttt attcttgtat catctttatc
    25561 gttagtttat tttgtacaag tatggtgagt ttgagcagta tgatcagtgc agtattgatc
    25621 actttatcta cgatcgtcct tccttatgta gctcctgtga ttttggctaa gcccaattgg
    25681 ttactgacga tcattgcctt tttagtttct tcctttatct tttatcggca taaagacaat
    25741 atcaagcgta tcagaaacca tactgaaagt cgaatcccgt ttggtttgaa tagcagcaag
    25801 aaaaaatcct gatacttttt cattccaaag agataaaacg ggagtgtgac aaatcgatgt
    25861 cacactccct tattacttac aggatagctt ttttacacac cttggtaaac ggtgttccct
    25921 gctaacttct cggtcacaac ctcttacttc actgtgatgg aatattttgt cttgaagatt
    25981 tcatgggcac ctagttgatt gatccctact ttttccatca agtttccact actgttcacc
    26041 gtgtcagcga ttccgcacca cggttcgata caaacgaaag gcgcttcttt tggataagga
    26101 gaccagatcc ctacataagg catatcttta tagcttaaag ttacgctatg ggaagatttt
    26161 tcacttcgaa tggcgtacgc atttagaccc cttgtttcaa aaaccaaggc atcttgctca
    26221 aaaagttcac gattcaaagc cagattcgta tttgtctgac ctaacgtctt ttgatccata
    26281 tcgatgaatg ggcctttcaa tggtaggcgt aatcttgatt tcaatggaga aaatgccaga
    26341 tagaaatctt caaatgacaa tccttcttca agaggtacat tgaaagcagg atgtccaccg
    26401 atagaaaaga acatttcttt ttcaccggta tttgccactt gataatgaac cgtgatgccg
    26461 tctcctccta attcatagct gatcactaat tcaaaatcaa atggatactt ttctaatgtc
    26521 tccggcgtac tccttaagat gaaactagcc atttcttgtc catgttcaat gacttcaaaa
    26581 tccatatccc gagcaaatcc gtgttgcccc atttgatatg ttttcccttg ataaacatac
    26641 tgatcatctt ttaaacgtcc aacaaaaggg aataaaaccg gtgcatgtct gccccaatac
    26701 gctggatcac cttgccagat atactctaaa ccatgttctt ttgatttcag actgatcaat
    26761 tccgcaccgt gttcagcgat ttcggcgatc agctggtcat tttgaataat aacagtcatt
    26821 gccattcctc caacttcgac ttacttttta aaatgggaag gctggaacaa acatttctat
    26881 ctgccccagt ccccttactt ctaataactg tgttttgcta actcgtcttt aaaacgggaa
    26941 ttcaatactt ttaaataagt tcccttcatg cctaacgaac gagattcaat gattccagct
    27001 gattccaatt ttcgtaaagc attgacgatc acagaacgag tgatgccgat actatcggca
    27061 atattagaag cagtcagacg accttcatct ccatccaatg cttcaaagat agcttgtaca
    27121 gccttcaatt cgctataaga taatgtgttg attgccattt ggacagccgt tgcactccgt
    27181 acatctgctt cgatgcttcg agacttctga taaaggatct gcataccgac aaccgtagct
    27241 ccatattctg ctaagactag atcgtcatct gcaaacgatt gttccatacg agataagata
    27301 atcgtaccca aacgttcgcc agctccaaag atcggaacga cagtcgtcag accaaatgga
    27361 tatttctctc ttgactctac cggaaatgca gtaatatcac tagtaattgg gatattagct
    27421 tcagttttca tcaactgtgc cactgtatca gtataagatt caggaaattg tttctcaaca
    27481 aacattgttt tgattcgttc attgttcaca tcgtgacgtt cattataacc tagtaatact
    27541 ccgtcacttc ctatgatata ggtgttgctg tcaagaatac cacctagtgt gacagccatt
    27601 ttatcgtaag gcaaatctgc ttgcatgtca aaagtattct tttgctgcaa aagtgtgttt
    27661 atcttgcggg ttttcgttag caagtctgtc attgtcgtcc tccgattttt tataaaatat
    27721 agcgacttaa atcttcattt gccgcaattg agccaagttt gtcatccaca tatgcttctg
    27781 tgatcgttat ttctcccatt tgcatatctg gtgcttcaaa taatagatct tctagtagtt
    27841 tttccaaaat ggtatgcagt ctgcgtgcgc cgatattatc tgtgtcacgg ttgacatcga
    27901 aagcgatttg agcgatccgt tcaattgctt cttttgtaaa cgtaactgac acattttctg
    27961 taccgatcaa cgcgacgtat tgttttacta aagcattatt tggttcggtc agaatcttca
    28021 caaaatcttc agctgtcaaa tcatctaatt ctacccgtat cgggaagcgt ccttgaagtt
    28081 ctggaattag atcacttggt ttagacaaat ggaaagctcc tgaagcaatg aataggacgt
    28141 gatctgtttg gatgatcccg tattttgtgt ttacttgtga accttcgaca attggcaata
    28201 tgtctctttg gacgccttct ctggatactt ctccagattg ctgtgattta gaagtgatct
    28261 tatcgatttc atcgataaaa ataattccac tttcttccgc taatttgatt gcctcactat
    28321 ggatatcagc atccttgact aattttgctg attcttcctt gatcaataac tctaaagctt
    28381 ctttgactgt taccgtccgt tccacttttt tcttcggtgt caaagcacct agagtttcat
    28441 ttaggtcgat ccccatttgc tccaatccat tgttcatcat tggtgcaggt ttcttttggt
    28501 cttcaacttc aatggttact tcacgactat ccagtaaacc cttttgtagt tgttccaaga
    28561 ctgtacggcg attgattcga atatcttctg tcacttcttc ttgcggttca gcggtatttt
    28621 gctgactagc attaaaaaga ttcatcattt gttcaaattg attagtggat tgtttctgtt
    28681 cttttttgat accaggtacc aagattttta ccaaacgttt ttctgcattt tttttagcac
    28741 ttgtgtatac acggctgtac tgctcttttt ctacgatttg gatcgcattt tctactaaat
    28801 cccgaaccat tgattctaca tctcttccga cataaccgac ttcagtaaat tttgttgctt
    28861 cgactttgac aaatggtgca ttgacgattt ttgccaaacg tcgtgcgatt tctgttttac
    28921 cgacccctgt aggtccgatc atcagcatat tttttggtgt aatatcttgt tgcatttttt
    28981 catctaactg caaacggcga tagcggttac gcaaagcaac ggcaacagat ttttttgctg
    29041 cgtgctgtcc tacgatatat tcatctaatt cacttacgat ttgtcttggt gtttgtttta
    29101 attcatacat atctactcac ctcttacagt tcttctacga taatattatg attagtaaag
    29161 atacagatat ctgcggcaat atttaacgca ttttctgcaa tttctttcgc actcatgtcg
    29221 ttttgagcat agtttttcat tgctcgggct gcagccaacg caaaattccc tcctgatccg
    29281 atagctaaga taccatcatc tggtgtgata acttctcctg tacctgaaac aagaagcatt
    29341 tctttatcat tcattacgat cagcatcgct tcaagttttt gcatagattg ctgtgtccgc
    29401 cattcttgag ctaattcgac agctgcgcgt tgtagattcc cgttatattc gtttagtttg
    29461 ccttcaaatt tttcttctaa agtaaacgca tctgcaacac ttccggcgaa acctacaaca
    29521 acttctccat tgtagatacg tcgtactttc tttgcagtgc ctttcatgac aacagattca
    29581 cccattgtta cttggccatc tccagccata gcaaatttcc cgtctttttc gacggcacag
    29641 atagtggttg aatgaaatgg tgattcgacc atgtttgttt cctcctaaat ttgttctttt
    29701 ccttattttt acgctcttgg atggaaagaa cgatagtttt tttgtaaact ttcttttgtt
    29761 acatgggcat agatctgggt agtcgataaa ttggcatgtc ctagcaattc ttggactgtc
    29821 cgcaaatctg ccccattatt taataaatga gtagcaaatg tatggcgcag catgtgagga
    29881 tggatatcac tatccaaact gctttttttg atcatttgat tcaagacata ttcaattcca
    29941 gtaggcgtga ttggttttcc atgatgattc acaaaaacga tatcatgctc ttcgtgatat
    30001 tttgtcatca atacctggcg gccttccctg aaatattctt gcagagcatc ttgagcaaaa
    30061 gaacctagag gagcatatct ctctttgttc cctttaccat ggatcaacat gacctctgaa
    30121 tcaaaatcaa tgtctgatac cgacaaactg ctacactcac ttaaacggat gcctgacccg
    30181 taaaggactt ccagtaaagc gcggttcctc aaatccaaag gactatctcc tgctacgctg
    30241 tcaaaaagtg cttgcatttc attttcataa aaaaaacgtg gcagtctcaa atttttcttt
    30301 ttgagatgaa cgtaagaaaa tggattttct tttatcactt cttctttgag aagatactga
    30361 taaaacgaac gtaggctggc tatcttgcga ctgatagaat ttctgctata gctaggacga
    30421 tgatcagcta atgcactcaa atagacacga accgtaaaat attccgcctt cagcagatca
    30481 gcgtctccag attcctccaa aaaatgtttg aaatggagaa tgtcttcttc atatgcttct
    30541 ttcgtttttt ctgaatatcc tctttcgaca atcaaataac gcaaaaattt ttgttcccac
    30601 gtggcttctg tcattttctc accttccttt tgtcccagag aataatttag cacagcgttt
    30661 ataaaaagac aaataaattg tcagaattta accaatattt ctaagtttgt tcacaattgg
    30721 cgcaattcct cacattttgt ttgagaaatt cttaagaaaa acgcaagaaa aagagcgaga
    30781 ctatccgtct caccctcttc atggagtttc cttactcatt tgggattgca gttttttcta
    30841 attctgtttt tattgcctca ttagctttta aagctcgttg tgcaattgct tcatatcttg
    30901 cttttttgtc tcgaatgcgc tctggcagtt caggaaacag accatagttg gcattcatcg
    30961 gttggaaatg ttttccttcc gcatgagtaa tgtagtaagc catacttcca atagctgttt
    31021 cttgtggaaa ctcgactggt tccatttctt ttgctaagcg tgcggcgttg attccagcaa
    31081 gtagtccgct cgctgcactt tcaacatagc cttctacacc agtcatctga cctgcaaaga
    31141 acagatcttc gcgtttcgtt gattggtaag tcggtttcag caattctggc gaattcataa
    31201 agctgtttcg gtgcatcaca ccatagcgaa cgaattcagc attttctaac ccaggaatca
    31261 tccggaaaac acgtttttgc tcgccccatt tcaagtgagt ctgaaagccc acgatgttgt
    31321 ataaagaagc tgcagcattg tcttgacgca gctggataac agcataagga cgtttgccag
    31381 ttttaggatc ttccaatcca actggtttca taggtccgaa aagcatcgtt ttgaatcctc
    31441 gctgtgccat tacttcaatt ggcatacatc cttcaaaata tttttctttc tcaaaagatt
    31501 taagttctgc cacttcggca ttgattagtg cctcatggaa agctttgaat tcctcttctg
    31561 tcatcggaca gttcaagtaa gctgcttctc ctttgtcata gcgggacttc aaatatactt
    31621 tatccatatc gatcgtagct ttgtctacga ttggtgcagc tgcatcatag aaataaaaac
    31681 catctgaacc attgaatgct ttgatgcttt ctgctaatgg atgagaagtc aaaggtcctg
    31741 ttgctactac ggtgattcct tccggtattt cagtaatttc ttcgtttatc actgttacta
    31801 atggatgctc tttgactttt cgggtaattg tttcagaaaa agaatcgcgg tcaacagcta
    31861 aggcaccacc agctggcact gctgtttcat ctgccgaagt gattactacc gaattcaatc
    31921 ggcgcatttc ttctttcaat aaccctactg cattagccaa actgtttcct cttaatgaat
    31981 tggaacatac tagttcagca aaattacttg tgtgatgcgc ctcagtcgat ttgactggac
    32041 gcatttcata taaacggaca gggactcctg cttgtgcgat ctgccaagca gcttcacttc
    32101 cggcaagccc tgctccaaca acatttacca ttttcaatga aagaacctct tttctattat
    32161 ttttggatgt cttcttcgta atctccattt acacagacta cttgtttacc gcctttgact
    32221 ttcttctcga ccagatatcc gtcacatttt ggacaatttc tgcccactgg tttatcccaa
    32281 gaagtgaatt cacattctgg gaaacgggaa caaccataga atagtctgtt tttcttagat
    32341 tttcgttcaa tgacttgtcc ttcatgacat actgggcaag tcacaccgat ttcttttacg
    32401 attggtttcg tattccgaca atcaggaaaa ttactgcaag cataaaactt cccatatttc
    32461 cctaatttta tcaccatcgg atgtccacag acatcacaat cgaatcctgc tggttcatct
    32521 ttgatttgaa ttttttcgat tttttcttcc gcattcgtca gttctttttc aaacggttta
    32581 tagaaacgat caaccacttt gacccacgct tccgtgcctt cttcaatttt atccaaatct
    32641 ccttccattt ctgctgtgaa atggatatcg acgatttgag ggaagaattc acagattaat
    32701 gaattgacaa tttctcctag ttcagtcggc tcaaatcttt tttgtgtcaa ttttacatag
    32761 tagcgtcttt ggatcgtatc aagtgttggt gcataagtgg aaggtcgccc taccccgttt
    32821 tcttctagtg cacgaatcaa cgtagcctca ctaaaacgtg ctggtggttg agtaaaatgt
    32881 tgttttggtt caatatcaac agattggact acatcgcctt cttcaagttc tggaagaata
    32941 ttttctttct cttctttgcc gtcatctcta ccttccacat acacttgcat gaatcctttg
    33001 aatttgattt ttgaaccgtt cgcaatgaag atgacaccat tttgttctaa tgtcactttc
    33061 attgtatcta aaatagctgg tgtcatctga ctagccacaa aacgtgacca gatcaatgta
    33121 taaagtttca attgatcttt atctaaatat tgtttgagtt catctggtgt acgaagcaca
    33181 ctcgttggac gcacagcttc atgggcatct tgtgcgcctt gagcattttt gatctttcgg
    33241 tgatcatgtc tagaaaattc ttttccatac gtatcttcaa taaatgctgc ggcctctgct
    33301 tttgctgtat cggcaatccg ggtagaatca gtacgcatgt atgtaatcaa gccgactgtt
    33361 ccttgtttac ccaaagtgat tccttcatat aattgctgtg ctaccatcat ggtttttctt
    33421 gttcgaaagt ttaacttacg ggcagcttct tgttgcaggc tacttgtagt gaaaggattc
    33481 gcagggtttc ttttgcgctc tttcttttct acttttttaa cttcgaagtc tgttccatca
    33541 attctagcag tgacttcttt tacactttgt gcatctggta atttcttttt cttaccgtcg
    33601 attccccaga aatttgcttt gaatttcttg cgagcttttt taaaattacc gtcgatgctc
    33661 caatattctt ctggaacaaa ttctcggatc tctttttcac ggtcaataat aatttttaaa
    33721 gcgacagatt ggacacgtcc tgcacttaac cctttcttga ccttacgcca gagaatagga
    33781 ctgatcgaat aaccaacgat tctgtctaag gtacgacgag cttgctgtgc atctactaaa
    33841 tctacatcga tcgttcttgg ttccttaaaa gctgctttga ctgcgtcttt tgtgatttca
    33901 ttgaagacca cccgattttt ttctttcaga tccaacccaa gtaggtacgc taaatgccaa
    33961 gcaatcgctt ctccttctct atccgggtca cttgccaagt aaactttttg agcttttttt
    34021 gctgcggctt tcaggctttt gatgacatcg ccttttccgc gtatagaaat ataatggggt
    34081 tcataattgt tttcaaaatc gatacccatt ttacttttcg gtaaatctct tatatggcca
    34141 acactggcca ttactttata gtttcgtcca agatatttct caattgtctt ggcttttgca
    34201 ggtgattcta caatcactaa atatttatac gccattactg aatggactcc tttccattgt
    34261 cgtgttccta ctattaaaag aggattcata caaatcgtag ctaatcatat ccattcagaa
    34321 aacgtttgtc aagaaaagca aatgaaaagt atggtgttat tctttaaatt ctgccaagat
    34381 atcttcaccc gaaaccgtgc aaactgcacc gtcttggatc aaatgatgac atccggtaga
    34441 atgttctgtt aaaatatttc ctggaacaga aaaaactgtt cttccaagat ccaatgcttg
    34501 ctgtgctgtt atcagagagc cgcttttttt cttggcttca aagacacatg ttcctttaga
    34561 caaagctgcg ataatccgat ttctcattgg aaaacaatgc tttttcgggc cggattgagg
    34621 aggatattca ctcaaaagaa gatgatcatt tgcaatcacc tcttgcaagt cacgattttc
    34681 agcaggatag acttgctcta tccctgttcc aatgactgcg attgtccgtc caccatgaga
    34741 gattgctgct tggtgaccgt atgtatctat ccctttcgcg cagccactga cgatcacata
    34801 tccagcttct atcactggtt ttagtaaata ataaactgtt tttttggcta aagcagaagt
    34861 gtgtcttcca ccaacaacgc ttaacatgtt acaagaaagt aaagatagat caccattata
    34921 aaacagtaca attggcggat aggtcaagtg aagcagctga gggggatatt tgggatcaaa
    34981 gcaagtgata aacgactgtt tcgattggat tttgccccag ttagcgtgaa tttcctgcca
    35041 acttttgcga aacagctccc ggtgtttggt tattttacct atcttaatga tgtcttcaaa
    35101 tccgatttct ttataaggat actgcatcat ccagttagca agtgcccatt ttccttgact
    35161 actgattcct tttgtataag caagtttcaa taaattttct tctatttgat acatcataaa
    35221 accgcctttc gtctctcttt ctaataagat acgtaaaagc ggctgttttt tattgtaaat
    35281 atttttttac aggtgcaaaa cttttacgat ggattggcgt aattccttgt cgttcaagtc
    35341 cttctaagtg ttcctttgtt ccataacctg cattatgcga gaaaccatat ccaggataaa
    35401 gcacgtcata ttctttcatc aattggtctc gatatacttt agcaatgata cttgcagcag
    35461 caatcgacac agatcgtgca tcccctttga ttattttttc ctgctgaata ggcaaatcca
    35521 aggtcatcgc atcgatcaac aaatagcttg gtacaatgga caatttttct actgcttgga
    35581 tcatcgctaa tttacttgct tcataaatat tcacatcatc gattgtctgc tgatcaacga
    35641 tcccgatccc gattgccagg gctttttctt gaacttgttg ataaagaagt tctcgctttt
    35701 tctctgataa ttgtttggag tcattcagcc ctaatatgat ctcatttttc ggcaagataa
    35761 ctgcagctgc cacgacaggt ccagctaatg gtcctcttcc tacttcatca atgccggcaa
    35821 tccattggtg accttgtgcg tacccttgct tttcaaagca aaacatttct tcatattttt
    35881 ccttaattaa tgcttccttt ttcaatcgtc gttcaaaaga agccagtgct tgctgcacgc
    35941 ctttgcgtgg atcatttctt aatgattcta gtgtaggatc atctattctc tgtatgcttt
    36001 tcaatcgttc tttgatactt tggatggatt cagtcatcac ttttttgctc catttcttcg
    36061 caacgatcca gtgtgtatcg tccaagtttt ccttgacgaa tatcatgcac gactaattcg
    36121 ctgccacgat catagtcttc tttataccca cgttttgctg taatatccat cagtaattcc
    36181 ggtgccaatt tttcttcttg ctcgattgat aaaccataac gatcgctgat tcttcctgaa
    36241 taatatcggg caaaaaagtc taatccgtaa atcgctaaat catctaaatg gacaagctgg
    36301 tctttgatcg cgcctgtcag cgctagtttt ttgccgattt cttcatcttc aaatttgggc
    36361 cataaaatcc ctggtgtgtc taacaattcc aactcattac ctaaacgaag ccactgctga
    36421 ccttttgtta cgccaggctt atttcctgtc tgtgcaattt tcttgcctac tagtcgattc
    36481 atcaacgtag atttcccaac atttggaata cctaagacca ttgcccgaat agcgcgaggc
    36541 ttgatccccc gagcagcatc tcttgcccgt ttttctttca atgcttcttt agccgcaggt
    36601 actagacctt taattccttt actttcttgt gccgtgatag ctaatgcaag atggccttgt
    36661 ttacgaaaat attcttgcca cagctttgtc tgttgtggat ctgccagatc cgctttattc
    36721 aataaaacaa ggcgaggttt ttgctgaatg atctgatcta gcattggatt acgagaagat
    36781 aaaggtaatc gtgcgtctac caattcaaat acgatgtcca catatttcat tttttcagaa
    36841 acttctcgtc gggcttttgc catatgtccc ggaaaccatt ggatggtcat tgttctctcc
    36901 attcctttca taccggaata ttccccggct ttacttgttt ttttcttttt caatataaat
    36961 tcactttttt attataaaga aattccatct attagttaag tgaaagtgaa ccagtcctca
    37021 ttctatcaca tcttcacttt tttgatgatg caaattttta ttttggtttc tatatatgaa
    37081 tctaaatttt tgacagcgtt tcctaaataa gagatgatag acgaacaaaa cagaaaggag
    37141 acgaaacaaa tgaatagtat ggtttttgtt aattttcctg ttgctgatgt caatcgttcc
    37201 gttgcttttt atgaaaagct gggttttaaa aaaaatgaag aattttctac tgaaga
//
LOCUS       DADGHT010000017        36409 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.017, whole genome shotgun sequence.
ACCESSION   DADGHT010000017 DADGHT010000000
VERSION     DADGHT010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36409
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.017"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(51..632)
                     /locus_tag="JX887_000755"
     CDS             complement(51..632)
                     /locus_tag="JX887_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAX1256763.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(638..1897)
                     /locus_tag="JX887_000756"
     CDS             complement(638..1897)
                     /locus_tag="JX887_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAX1256764.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(1899..2945)
                     /locus_tag="JX887_000757"
     CDS             complement(1899..2945)
                     /locus_tag="JX887_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256765.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(3180..3455)
                     /locus_tag="JX887_000758"
     CDS             complement(3180..3455)
                     /locus_tag="JX887_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAX1256766.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(3698..5008)
                     /locus_tag="JX887_000759"
     CDS             complement(3698..5008)
                     /locus_tag="JX887_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAX1256767.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(5190..6419)
                     /gene="rpsA"
                     /locus_tag="JX887_000760"
     CDS             complement(5190..6419)
                     /gene="rpsA"
                     /locus_tag="JX887_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAX1256768.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(6554..7234)
                     /locus_tag="JX887_000761"
     CDS             complement(6554..7234)
                     /locus_tag="JX887_000761"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAX1256769.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(7283..7918)
                     /locus_tag="JX887_000762"
     CDS             complement(7283..7918)
                     /locus_tag="JX887_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAX1256770.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(7984..9387)
                     /locus_tag="JX887_000763"
     CDS             complement(7984..9387)
                     /locus_tag="JX887_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAX1256771.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(9374..10405)
                     /locus_tag="JX887_000764"
     CDS             complement(9374..10405)
                     /locus_tag="JX887_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256772.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            10436..10657
                     /locus_tag="JX887_000765"
     CDS             10436..10657
                     /locus_tag="JX887_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAX1256773.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(10822..11559)
                     /locus_tag="JX887_000766"
     CDS             complement(10822..11559)
                     /locus_tag="JX887_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAX1256774.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(11712..13052)
                     /locus_tag="JX887_000767"
     CDS             complement(11712..13052)
                     /locus_tag="JX887_000767"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAX1256775.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(13289..14812)
                     /locus_tag="JX887_000768"
     CDS             complement(13289..14812)
                     /locus_tag="JX887_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAX1256776.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(15190..15801)
                     /locus_tag="JX887_000769"
     CDS             complement(15190..15801)
                     /locus_tag="JX887_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAX1256777.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(15924..16049)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(16131..16847)
                     /locus_tag="JX887_000770"
     CDS             complement(16131..16847)
                     /locus_tag="JX887_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAX1256778.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(16853..17422)
                     /gene="scpB"
                     /locus_tag="JX887_000771"
     CDS             complement(16853..17422)
                     /gene="scpB"
                     /locus_tag="JX887_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAX1256779.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(17406..18203)
                     /locus_tag="JX887_000772"
     CDS             complement(17406..18203)
                     /locus_tag="JX887_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAX1256780.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(18173..18544)
                     /locus_tag="JX887_000773"
     CDS             complement(18173..18544)
                     /locus_tag="JX887_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAX1256781.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(18563..19450)
                     /gene="xerD"
                     /locus_tag="JX887_000774"
     CDS             complement(18563..19450)
                     /gene="xerD"
                     /locus_tag="JX887_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAX1256782.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(19546..20019)
                     /locus_tag="JX887_000775"
     CDS             complement(19546..20019)
                     /locus_tag="JX887_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAX1256783.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(20124..20987)
                     /locus_tag="JX887_000776"
     CDS             complement(20124..20987)
                     /locus_tag="JX887_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAX1256784.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(21183..23282)
                     /locus_tag="JX887_000777"
     CDS             complement(21183..23282)
                     /locus_tag="JX887_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAX1256785.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(23502..24611)
                     /gene="rpoD"
                     /locus_tag="JX887_000778"
     CDS             complement(23502..24611)
                     /gene="rpoD"
                     /locus_tag="JX887_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAX1256786.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(24635..26476)
                     /locus_tag="JX887_000779"
     CDS             complement(24635..26476)
                     /locus_tag="JX887_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAX1256787.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(26658..29051)
                     /locus_tag="JX887_000780"
     CDS             complement(26658..29051)
                     /locus_tag="JX887_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAX1256788.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(29158..30018)
                     /locus_tag="JX887_000781"
     CDS             complement(29158..30018)
                     /locus_tag="JX887_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAX1256789.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(30077..30598)
                     /locus_tag="JX887_000782"
     CDS             complement(30077..30598)
                     /locus_tag="JX887_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAX1256790.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            30918..31637
                     /locus_tag="JX887_000783"
     CDS             30918..31637
                     /locus_tag="JX887_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1256791.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            31663..34254
                     /gene="mprF"
                     /locus_tag="JX887_000784"
     CDS             31663..34254
                     /gene="mprF"
                     /locus_tag="JX887_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAX1256792.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(34442..35629)
                     /gene="tuf"
                     /locus_tag="JX887_000785"
     CDS             complement(34442..35629)
                     /gene="tuf"
                     /locus_tag="JX887_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAX1256793.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            35997..36353
                     /locus_tag="JX887_000786"
     CDS             35997..36353
                     /locus_tag="JX887_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAX1256794.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT        10129 a         7701 c         6241 g        12338 t
ORIGIN      
        1 attccacatc cagctgacct ttgtcttttt tagtactata ctatttttaa ctaattgtta
       61 tgttcactta cccggttact tttcttttgt gtctgcaaaa ggatctttcg gttaacttca
      121 tcagataatt tcaaaaaagc atccctatct ccatcttcta gtgcttgatc gatttgagca
      181 taaagcattt ttagttttgc ctcttcttct ttttcttgaa aatatcgttc aattaattca
      241 gtatcttctt cactgactga agaatcccaa gaagaaaatg gattgtcttc taagatagat
      301 agatattctc ttgtctgcca agcattttcg aatatacatt ccacatataa aggctttttc
      361 caattcaaac ggatttcatg aaaaatctgg tctgtgtccg taaattcttt tccctgcaaa
      421 aacaatttca tgggttcccc ttcaacagat agatcactga tctgcagtcc tcgatccgca
      481 aaattcgccc cttcaacaaa gtggacattg cttaaaatcg cttcatgatt ggcaagataa
      541 ttcaagatcc aaaaaacttc tcttcggcta aaagatacat gattgaccat ccacgttaaa
      601 aaattcttct tttcccgtac atcaattagc atttttctca cctctctgtt aggtcatcta
      661 ataatgacag tgcctccata tctcctggtt caagtgttaa ataataagtc aataattctt
      721 gcgctctttt cagctgccct tcttctctta agaaaaaggc atactctttc aagaaatctg
      781 gttcatgtga tagttcatga taagcctgtt catagtgtac agctgcaacg gtaaagtctt
      841 ctaattcatt ataagcatgg gctaggttcc attctgcata aggattagca gtttcttcca
      901 tctgattgat cacttgtatc acatcttcat atctttcatc atccaagtaa agattactta
      961 aagtaagtaa tgtttcatct tgtttgtctc ctacttctaa agctttcagt aaaagttctt
     1021 ctgctcgctg tctatcatgc agacggaaag cattttccga ggccaggtga taaagttcga
     1081 cttggtaagg attttctttg attccttctt ctaacactgt ttgtgcttct tcaatcattt
     1141 cttcttcttg aagagcttgt cctagatata gatataacga ttgataatgc ggattaactt
     1201 ctcgaagttc ttccagatag ttgattgcct gctgattttc tttcaattga agattcgtaa
     1261 aagctagctg gaacagtcga tcatctgtcc tttcttcttt cagtgcttct tctaaaggta
     1321 cgatagctgc ttcgaattct ccttgcatac ttaaggattg tcctaaacgt tcctgcatcg
     1381 agattcctga aatttcattt atcccgcttg ccaacaatgt ttcataaacc actgctgcct
     1441 ctttgaaacg atcaactgaa aaatacaatt cagctagcgc aaactggatc aatggttcat
     1501 caggaagcaa cccagctgct tctttcaatt ttgcttcact cacttcaggg attccgataa
     1561 cttggtacaa atcagctatc gccaataagc tttgcggata gtaatcactt tgcttatcca
     1621 ctttttccag gtattcaaaa gctaagtcga tctcattatc ttcgattgca atttctgcta
     1681 acgggatgtt cagtccgtca ttttctgggt attggttgat cagttgttca aaaatctgtt
     1741 ttgcttcgat caaaaagcca atagccagca attcttcgcc tagttcagct aatatatctg
     1801 ctgggtcttc ttttaatgct ttttctaaaa agatttgtgc ttgtgacaag tcttcatctg
     1861 ataaagcttg caacattttt tcgctatttg tattcatttc aattccctct tatctcactg
     1921 acgatttgtt gaaataccgt cattgttctc aataattctt tttcgtttgg atgttggtat
     1981 ccgtctatta tacctatttt ttctaaaaca agtatttttt tgcttttttc tgccaaaaaa
     2041 agaacttttt ccaaatactc catctttgaa atctgttcca gccagtggat tggatagcca
     2101 agcaagtcca gccacacaaa aaagtttttt agttggaaat caaaaggata tgcttggaga
     2161 ttccacacga aatgaaacat cattcctaaa aattttttca tactagcaga aagtagatgg
     2221 ccattttcgg tcagataaaa agcttgttca aacagtttac cataatttga caggttttct
     2281 gcctctaatt gataaaaata gatcatttct tcgatcatcc cggcaaacgg ccgagtcgtt
     2341 aattgctttt tatttggata gtttttatac agattttgca aaaaacgatg atcacaaatc
     2401 attccgcaac agataaaagt caaaaagtca atctgctttc cgtccacctg ccgctcgctg
     2461 attgtttgat cataaacgat gcgttctggc agattgatgg tttgcagcac tacacgattt
     2521 ggtagctgca aaatcgtccg ctgcggtgtt aatgctcggc ttagagaacg gatcgataca
     2581 gggatcatcc atagtgatga atcaagggtt gtatgttttt gaaaaaaacc tgccagatcc
     2641 atgatccctt catttccaaa tccgatgata aacatggatt gattttcggg atagcgtttg
     2701 acgaaatcaa gcaggttctt taattctgtt aaatgattgc attgagtgtt ggcacaaata
     2761 taccagtcat tgtttgcttg atttgcaaat aacgggttga tcttatctgc aaacaaatca
     2821 taatagcgct gattcgttaa aaataagatt ggctgatcaa tggaaagttc tcttagctga
     2881 ctgactagcg tttctccgta aaacactttc gtcaacgcat cttctacttg ataatcaagt
     2941 tccatacgca tccctcctct tcttattttt attttaccat tagtaagcaa attctagaaa
     3001 agataagagc aaagctcacc tcataacttg caaataaata aaaattaaat aaaatacatg
     3061 tgttttctat gtatgacata cggattcgga atctctgtct cttatttatt ccttttctgc
     3121 taggaaataa aaagaaaagc acttgtagcc ctagagccac aagcgctttt tcaactgtct
     3181 tatttaacag cgtcttttaa tgctttacct ggtttgaatg caggtacttt gctagctgga
     3241 atttcgattt cttcaccagt ttgtgggtta cgacctttgc gagctgcgcg ttcgcgaact
     3301 tcaaagttac caaaaccgat taattgaact ttttcgccgt tagctaaagc atcttgaata
     3361 gttgaaaata cagcatctac tgctgcagtt gcatcttttt tagttaaatc agtagctgaa
     3421 gcaacttttt cgattaattc tgctttgttt gccatggata gattcacctc ctccacaaga
     3481 gatatgatag aaatatcatt tagttaaaac tttctgagtg gtccagaagt ttaaaaagaa
     3541 atattgatta acttcaatat tctgttatca cgatatcata tgaaccgctt aatagcaagg
     3601 tttttaccaa ttttcacatg ctttttttag tcatagaaac gtaacaaacg aaactgtctt
     3661 tttcttttga aaaaaaaacg tcgatatggt aaaatgccta ttttctccta cgagggataa
     3721 ttcggatgga cgtcccttca aaagtaaatg cttttctgat ttgattttct aagaaacgtt
     3781 cataagaaaa atgcatcaat tcctcttcat tgacaaaaac gacaaatgta ggtggtttga
     3841 cagcgacttg tgtagcataa aaaatcttca ggcgttttcc tttatctgtt ggtgttggat
     3901 tgattgctac agcatccata atgatatcat tcaacacagc cgaagagata cgaagattct
     3961 ggttcatact tacttgttcg atcatttcag gcagacgttc caaccgttgt ttagtcactg
     4021 cagaaacaaa aacgattgga gcgtaatcaa gataccggaa ttcatcacga atctcttgtt
     4081 cgaaatcacg cattgtattg gtttctttct ttacaagatc ccatttattc acgacgataa
     4141 taattccacg accagcttca tgggcgtaac ccgctactcg cttgtcttgt tcccgaatcc
     4201 cttcttcagc attcagtacc atcaaaacga tatcagaacg gtcaatggca cgcattgcac
     4261 gcatcacgct gtatttttca gtattttcgt atacttttcc gcgtttacgc ataccagctg
     4321 tatctatcat taagaatttc tgaccacttt cagaaacgaa gtgggtgtcg attgcgtctc
     4381 gggtcgttcc ttcaatatcc gaaacaatta cacgttcttc tcctaaaatc gcattgatca
     4441 aagaggattt accaacattt gggcgaccaa tcaaactaaa cttaatcgtg tcgtcgtcct
     4501 cttcttcagt ctcttcagag aaatacttca ctgcttcatc taaaatatca ccaatcccta
     4561 gtccatggct tcctgaaaca ggataaggat cgcctagccc taaggaataa aattcataga
     4621 tatcgtttct catttctgga ttatctactt tattgactgc taaaatcact ggtttattac
     4681 ttctgtataa aattttcgca accatctcat ctgcgtctgt cacgccttcg cgtccgctga
     4741 ctacacaaat gattacatct gcttcttcaa tcgcgatttc tgcttgatgc ttgatctgat
     4801 ccataaaagg ttcatcgcca agatcaattc cgcctgtgtc gatcacgctg aattctcgac
     4861 ctaaccattc accttttgca taaatacgat cacgagttac tccaggagta tcttcgacaa
     4921 tcgagatacg ctcaccagcg atgcggttaa aaatcgtaga cttaccgacg ttcgggcggc
     4981 caacgattgc aattgttgga tttgccatat tatttcctcc tcacaagttt ccaatctcac
     5041 ttagtttaac gaatgcattg ccaactttca agcatagatt gtcaattaaa cgaagtattt
     5101 ttattcctta ttgaaatact aatcgctttt caaaagaaaa actgagacaa aagcagctgc
     5161 tttcatctca gtcacagata caaaatcaat tatttttcag aatcatcggt tgctttttct
     5221 tctacttctt ctttcaacgc atcacctaaa atgtctccca tagtaaatcc agtattttct
     5281 tctggtaatt cataagactc aacatttttt ggttcttctt ctgaagctgg tttttcttct
     5341 aaagctttga tactcaatgc aatacgatgt tcttctggat ggatctctaa tactttcact
     5401 ttcacttcgt caccttcatg aagcacttca tgtggtgtcg caatatgttt atgtgaaatt
     5461 tgagagatat ggactagccc ttctactcca gggaacactt caacaaaggc accgaagctt
     5521 gtcaaacgtt taactgttcc gtctaatact gtgccaactg gagcttttgt atcgatttct
     5581 gaccaaggtc caggctgtgt gtctttgatt gacaaggaaa cacgttcttg ttcaggattg
     5641 atagacaaca ctttgacatt tacatcatca ttgacagcca atacatcact tggttttgct
     5701 acatgactat gtgaaatctc tgagacatgg actagaccgt caattccgcc taggtcgaca
     5761 aatgcgccaa aatcagtaag acgtgcaaca cgtccactga gaacatctcc ctcatggata
     5821 gttgaaagaa tttctttttt cttttcttct ctttcgtttt ccactaccgc tttatgcgat
     5881 aagatcaaac gattttctga tggttcgatt tcgatgattt taaagctcaa tgttttgcct
     5941 ttatagtctg aaaagtctgc aacaaaatga tcttccacca ttgatgcagg gacaaaacca
     6001 cgtacaccga cgtcaacgac taaaccgcct ttgacaacat ttgtaacagg tgcttcgatg
     6061 accttgccct cttggaaatc tctttcgata tcttcccaaa cttttttagc atctaaacgg
     6121 cgttttgaaa gtagatagct gccgttttct ttatctttgc cgatcgtact gataacgact
     6181 aaatctaata catcaccgac ttttactact tcgctgatat cttctaccgg caaagttgat
     6241 aattcttttg ccggaacgac tccttcaact ccagcccctt cgattccgac aatcacttgt
     6301 ttgtcttcaa tgactaaaac ttcgccctta acaacatcgc caacttttac ttcttgtacg
     6361 cttttcattg cgtcttccat tgactggttg ttctcttgat tttgatcaaa ttctgtcata
     6421 acacttgtcc tcctaaccaa cattctgccg taagtacggt actgttttta gtttaattga
     6481 ttattcaaaa aaaataaagc gatttcgttc gttttccttg aaaaaacaat tgtttttcat
     6541 tttttttctt aatttaaaaa agaagataac cttttttcaa aacaacagct tttattgctg
     6601 caacgacttc tggaatcgat ttgccagtcg tatcgatacg aacagcatcc tctgcttgct
     6661 tcagcggaga gacgtccctt gttgaatcat aatggtctct ttcctgtatc tctttcgtca
     6721 gtgtttcaag atcagtcgga attccttttt cttggttctc tttgaaacgt ctttctgcac
     6781 gctcacttac gcttgctact aaaaagattt tcacttctgc attcggtaat acagctgtcc
     6841 cgatgtctct tccgtccatg acaacgccac cgcgttcccc tatttttcgt tggacagcaa
     6901 ctaattcttc tctgactttt ccatgtgcag agacttcaga aacagctttt gtgacatctg
     6961 gttgacggat ttctaaagtc acatcttttg atgctatgaa tacatgctgt ccatcttctt
     7021 gttgcgaaaa agagatagga tactttttga tcagcgaaac tagcccttct tcatctgaaa
     7081 aagatacatt gttcgtaata gctaaataag ttactgcgcg atacatggca ccggtatctg
     7141 tataaatata attcaattct tttgctaata tcttggcaac ggtacttttc ccagatgaag
     7201 caggcccgtc gattgcaata ctgatttgtg tcatgatata actccttttt ctcagaaaaa
     7261 aagccgcaaa gcgcggctat tattatttaa ttcttaattc ttgaccaggg taaagcataa
     7321 agttgtttgg atctaagcca ttcaattcaa acaattgatc agtggtgatc cctgcacgct
     7381 cagccacttg ttttggacct tcgcctgctt gaacagtcgt tgttgaaccg gctgcagctg
     7441 atgaagaagg tgttgtttct gctgcattgc tgcttgaatc ccctgcttga taagttgcct
     7501 cacttgagga agtcggtgtt gtctctgctg caatactgct ttctgacgtt acacctgtat
     7561 cttgagacac agtagattct tccgcgattg tactagattc tactgttgaa gtctcagttg
     7621 actcctcttt tgttgtactt gtagaacttt ctactactga tgtcgaagtt tcagaagaag
     7681 ttgctgctgt tgcattgttg cttgatccat ttctgatcca gaaataagca cctgctggaa
     7741 tagcgataca taagaccagt aaaatcaaaa atagcgaaag aaataatgta tttcctttct
     7801 tttgttgtct ctgagaactt cttgatgaaa cttcatcatc tgtatcgtag attggttgtt
     7861 cccatggttc ttgtgtttcg ttattttctg tagattgatg tctatctttt ctgctcactg
     7921 ttttacctcc taaactctat cgtgtgtatt ataccatagg aaaaagtgtc ttgtcctaaa
     7981 aaatcaatgt tccatgtttt ttttaaataa atttagtaaa atcgttcccc aatgaagttg
     8041 ttcagtctta gaaaaaagct tcctctttgg cagaagttct gcttttgctc catcaatatc
     8101 acaacaattc tgcggctttt cggagagttt ttcgccaaaa taagctaaga tgaattttct
     8161 gcggcagttt tcttcattaa tatagcgaag catctgctgc aggcggaatt ctttttcttt
     8221 ttcctgacgt ttgagccgtt ccacccaatt ttctggtttt tcagactgct ggatcagctc
     8281 catccatttt ttttgcagct catcaaaggg agcttgctct gtggcatatt ccaaataaag
     8341 ctcaaaactt tgtcgctgtt ctctagaaag ttgattaaag aaataatgga tacgttcatc
     8401 cccactttga taaaaaagaa ttgctgcact ttcttcctga tctctgcctg ctcgaccgat
     8461 ttcttgtaca tagttttcta gactgtctgg caaatcataa tggaccacat aacggatatc
     8521 agatttatcg atccccatac caaatgcatt cgtagcaatg agaaactgca gctgattttt
     8581 tacaaactgc tgttgaagtt gtcttctttg agctgcatca agaccaccgt gatagtatcc
     8641 aactgtaaaa cgttccctga ataaatgata caatcgttcg acttcttttt ttgttgcaca
     8701 ataaatgatt gccgctcctt gtgctctttc catgaagtgt tcaagttctt gttctttttg
     8761 ctgcgttttc cgaacaaaaa gcgagatatt ttgccgattg actgattgtc tgatctcttt
     8821 tggtggtcga tcaaatagta catgacgtat atctcttgct actaaatctg ttgctgtcgc
     8881 cgttagtgcc agtgtgaccg ggtttcctaa aagctttcgg atttttccta actgttgata
     8941 ttctggacgg aaatcaactc cccattgaga cacgcaatga gcctcatcta ctacatataa
     9001 cgcaatattt tgttttttca gatgctctaa aagagaagga ttagtcaaca tttcgggact
     9061 caaaaacaaa aatttatatt gcgatagatg acggaggacg tatcttcttt cagattgcga
     9121 aagtaaacta ttgaaagcag ctactcgttt ctcccctcgt ttttgtaatt gcgtcacttg
     9181 atcttccatt agagaaagca gcggtgacac gatgatgacc agaccttcca ttaaataccc
     9241 cgtcaattga tagcaaaggc tttttcccgt tcctgtaggc aaaatagcga gagtatcttc
     9301 tccatcaagc aacgcctgaa taatttcttc ttggccggga cgaaatgaat caaatccaaa
     9361 atattttttt aattcattta ttaacattct gtatcgcttc ctttctcaat agatagattt
     9421 gatacaaacg aaattctcca taatctaatt gtccatctac attccattcg ctaaagcgcc
     9481 actctcgcac ggaatcctta tttggttcca aacgttcgat tgtttctgca gagagaatcc
     9541 actcgtatgg aaaatcatca aaaaacaagg cccactcaat aagatgatct gttactgttc
     9601 ctctttttaa atgacggatt gccatgatct ggtcaattgt ctgaccattc ataaacatct
     9661 gcttggtgat catcatgctt tgattgaaat tttgctgtaa taatgaatcg atcaaagcgt
     9721 gccaaagcga atctggccgt ttttcgattt gtgctaacaa aaggtggata catctgcttt
     9781 gttgcagata aaccgctgac tcatcattgt tttttgccag ctgataagga agcagccctg
     9841 ttcgctcatt tccagataat tggttagcta aaaaatctgc tgcttcttct ggtatctccg
     9901 aaaacagctg caccaaactc tcatacgcag tatcaatcaa aatttcacgt ggcaattggc
     9961 tttcactaag ccattttttt agttggaaag tataaaaagg acttgtctct gctggaagat
    10021 agtcttgaat acccgttgcc agattagaaa ttacttgaac agcaaattta atgagccgcc
    10081 aactagtttc ccctgttctg ccatagcggt caaaacgcaa accagtatgt tctatttgat
    10141 gttcggacaa catatcagcc cctgcaggcg ttagctttgc ttcattttca tttatttcga
    10201 tccaaccttg ctgcgcaatt ttttgcaaaa tttgataaaa cttatcctgc ttcaattctg
    10261 gaaaactgtt atggataaac aaaagttcgt gggtaaatcc ataaataagt actgaagtcg
    10321 ttcgttttcc cacaaggagt tggtaaagag aactaatccg cagcttgtgt cctgatgaaa
    10381 atagcgataa aataaaaaca atcatattat tctccttaag ttaggatggt tagaaatgtc
    10441 actactatgt aaacttgtac ctgaacgctg tattgcatgc ggtctttgtc aaatcgaagc
    10501 gccagatatt ttcgattatg atgaagaagg aatcgtttta tttgcccaag aaccagaggc
    10561 tcatcaacag ttcgtgatgc cggaagaaga aacatatgta aaaaaagcgt atcaaaaatg
    10621 tccagttcga gcgattttat tagaaaataa aatataaata taaacgaaac tttaaaaacg
    10681 tacactaagt tctctaaact tgaaaataag ccgggatctg tttctcttgt tccgtgaaat
    10741 cccgacttat tttgaaagat tcatttgcta tctatagtta attgactagt tttttcacgg
    10801 accctatagg acccatttat attatttcaa ctttttcagc cagttttcca atgtattgac
    10861 gatcacagtt tgctggtctg cgttagaaat ttctgcctct ccatctcctt tttgctcacc
    10921 atagctgcca aaacctccat gatttccgcc attgattgat acatactctg ttctttccgg
    10981 taaatactgc ttagcttctt gataagcttc ctgattcaat actttatctt ttgtcgccgt
    11041 gatcgataaa acaggaacag ctgattctgt caatgttcct tttttgtcgg gataacttgc
    11101 catgaagaat acccctttta aatgtttgtc tgaatgattc ttattgacat aacgacttgc
    11161 cattacgcca cctaatgaat ggccaccgat cacataatcg gaatttggaa aatcttcttt
    11221 gaccttatcc gctttgtttc cgcccatcac tgctagatca agtggcattt tgacaatagc
    11281 gactgaaaag ccgttttttg ctaaatcttg cgcccaaata ctataacttt ctggctctac
    11341 gagagcacca ggataaaaaa taagtaatgg agactttcca tgattctttt tctctccttc
    11401 aaaaaataag taatcttctt tgttttttcc ttcttttacc aacacttgcg cttctgacga
    11461 tggttcgtac gtattttgct gtatatagta ataaccggct ccaccgagta atcctaaaat
    11521 gatgactaag ccaattagta ttcgtctaaa tattttcact ttctcccacc ttttctatct
    11581 gagtgacccc tttttcttaa tcaagtatga ttatacctta aaaaaataag agagaaatgc
    11641 aaactttcca gcatcaaata aaaaaagacg gaatatccat ttgaatatcc gccctttttg
    11701 tatgtttatt tttatttagc acataaacga tacacagctt ctgcataaat ttccattgct
    11761 ttatacatac tacttaattc ccatcgttca ttcgcctggt gcataaagtc aggagtatca
    11821 gggaacatcg caccgaatgc cacacactgg ttcatcgtac gagcaaaagt agcgccgcct
    11881 gatacaaacg gttcagtcat gtctccagta atatcgcgat atgtccccaa tagatttttc
    11941 actaactcac tgtctagtgg cacgtataat gaatcaagga agtcaaattc ttcataagtc
    12001 aacccatatt tttctgctgt tttagttaat ttagctacta aatcatcttt cttgaatgta
    12061 acagggattc tcatatctac accgattttt gtttgttctg gtgtgatttc caaacttgca
    12121 aagttcatcg ttagctcgcc ggattgttca tcttctgttt tgcccacgac agcttcacca
    12181 gttgcatttt cttgaactaa ttttcctaag aaattgattg ggccaaaatc aaatacttct
    12241 gaaagagcaa ttgccagacg agaaatagca ttcactcctt gtgctgcatc tttcgcgtgg
    12301 atacttttac caagaacgac gatgccttca ccttgttctt cgaaatcgaa ttcgtgtttt
    12361 ttcaatgctt cttttacttc agaaagcttt tctccagagt aaggagctgc atcaggaaca
    12421 acattcaacg ctcctccagc ttttacagaa aactcgttcg ttcctggtcc tgtcaagtaa
    12481 gcttgcaata agcctttttc tgcataaatt aaaggaaatt cagcatctgg cgcaaatcct
    12541 tgcgtaattc cttcttcttt ttcgttatat ttttctaaac aacgccataa attttcttca
    12601 tctgtaccaa agataaaacg aatacgtgtc ttgaattcca cgccagcatc aatcaaagct
    12661 ttgacggcat acattgccgc aatagaagga cctttgtcat cttgggatcc gcgaccaact
    12721 aaccagccgt cttttatagt tggatcgaat ggttttgttt cccaattatt ttcgtcccct
    12781 gctggaacaa cgtccatatg acacaagata ccgaataatt catctccaga gccaatctct
    12841 gaataaccgt aatagccttc tggatcttta aatgttctaa atcctagctt ttcactgatt
    12901 tccaatactt tatccaaagc ttcaatcact tttttaccga agggatgtcc ttgtcctgaa
    12961 tctgcttcat ctagtacgga aggaattcgg atcaattcgc tcaatgattc taatgcttgt
    13021 tcatgatgtt gttctgtcac aaattttttc atgatattat cctcctaata tgttaaaaag
    13081 ggtcatgtca aattcctccg acacaacctc ttcttctcaa ataatgacgt tttaagcctg
    13141 ctccatcagc aagcagaatg ttcttaacaa atgatgaaag aaaaaacact cactgaatgg
    13201 agctattgac ttatccacgt gcttatcgat agccgtttat cggtttcttc attcttatga
    13261 tagaccttgt acctgtattt gtctaggttt agaacattgc tgctacacct aggatcacac
    13321 agatggctac aaataatatc gcaattaatt taccggtaaa tttccaccac actgaaacat
    13381 cgaaacgagc aattgctaca gcacccatta cgatagcaga tgttggtgta attaagttta
    13441 ctaaaccaga tgcagattga taagcagtga ttactaaatc cttaccgacg ccggcaaatt
    13501 cacccatagg tcccatgatt cccattgttg cagcagctaa gccggaagtt gaaggaatca
    13561 agaatgacat agggatatag aaaataaatg taataatgat gaatacactt gaagataatg
    13621 aacttaatcc ttgttcgccc caatgtaaga tggtgtctgt gattaatcca ttgttcataa
    13681 ccacttggat accacgagca acagctacta cgattgctac accgatcaaa tcagaagcac
    13741 cagctaaaaa ttcagagaca aattcagact ctttcatgcc ataagtgatt gctactacga
    13801 tggacattac taagaataac atagtaattt ctgggaagta ccagtcacct aatggaagca
    13861 tgcttttacc tagaaccgta cctagtaccg gaaggtttgt taaccagttt gtcaatgatt
    13921 caaaaatcgt gaaattcgca ttcaaggttg tccaaggaat caaactgatg atcatgatac
    13981 caaaagtaat aaagaacaat acattaacat gtttttgttt tttcgtgatt acttcttgac
    14041 gaccgattgc ttcaatatcg aaatgcttca tatcttcttt acgttggttg tatactaatg
    14101 attttgttgg atctttttcg atctttgatg cataacgata cacatataca atagaaatag
    14161 ctaacaaaat aacgaacatc aagaatcgaa gaccaatacc ttcacccatc gaaatcccaa
    14221 cagcttgtga agctacgcct gttgcaaaag gatttaccgt tgaagctaga cagcctactt
    14281 gagaccctac taatacgatt gctacagcta ctactgtatc aaagcctaca gccatcatga
    14341 ctgggatcag taaagcatag aatggaatcg tttcttctgc cattccgtaa gtagagccgc
    14401 ctaatgcaaa taacagcatc aatactggaa taagcatttt ttcttttcct ttgaatttct
    14461 tcacaactga agcaatcccg gcatctagtg cccctgtttt gttgataata cctaaaaatc
    14521 caccaacaac caaaatgaag aaagagattg ggattgcagc aggtgtttct ttagttagct
    14581 cccccgctgg tacacctagc atcccattga ttggcgccat gaaaatatcc cacagccctt
    14641 gaggattttg ttgtactcgt tcatatgatc cagcgacgat gttgcctgca tcgtctacac
    14701 tatagtgccc agctggtata aaccaagtaa gtacagcgat tactgcaata ataataaata
    14761 agaccgtata cgctgaaggc atttgaaatt ttttcttttt tgtttgttcc atcttcttct
    14821 tcctttcttt tccgttagag acaacaattt tggctctaat gttattttat caaaaagagt
    14881 atcagaacaa aaataataac acgcattttg taaaactttt gttcaaaaag ttcgtttttc
    14941 cctattccct cctctttttt caggttttta aagctttctt ctttttcatt gtagcgtttc
    15001 ctttttttta taaacaaaca ttttcgtctt ttaaaaggag aagaatttca catttgcaaa
    15061 gaattgattg atttttatgc ataaatcaaa aaaatactca aaacaaacaa ataaaacgtt
    15121 tacattattg catgtcttgt atttttttcc aaaaaaaaag accaagaaat ttcttgatct
    15181 ttttgatatt tatttgactg ctgtatgacg ttgttcgaac tgatgttgtt ttcgacttaa
    15241 ccatggaaga agttgcgcat gcagcactaa aaagacagca ctcacgatga atcctttgat
    15301 caagttgaaa ggaacgatcc caatcagtac atagtttgct aaagacatgc ccagcatctg
    15361 tgttgcgttc agccctaaaa acattaagta aagaggcgta ataacgaaat aatttgcgat
    15421 actcataaaa atagttagag cgatggttcc tgtaatgaca cctaaaaatt tgtttcttcc
    15481 tttatgctgt ttctttacac taaagaaata ataaatcggg aatgtaaaga tcgttgttga
    15541 taagaaacta gcagtgtctc ctaccaaatt atccggagaa aaacctgtag tcagcagatg
    15601 taatactgaa cgcaagaacg ctgttgcaac tccggccgct ggaccgaata agaacatgct
    15661 gatcaatacc gagatatcac taaaatcgat cttcaaaaaa ctaaaagccg gcatgatcgg
    15721 aaaagcaaaa tactgtaaaa ctaatgcgat cgcagcaaac atcgctactg caaccatttt
    15781 ctgtacacgg gtgttcttca tttgaaatcc tcctgttagg actcctcttc agcgaacttt
    15841 ttgacgtttc tctccaaatg aaaaaactct attttccagg gaaaatagag ttagagttat
    15901 ttgatcaagc gtcgtcaaat aagctctatc ttctttatcc agactatact gtcggtatcg
    15961 gaatttcacc gattcagcta tttttttgca aaataggtcg tggactataa ccaccggtcg
    16021 ggaatttcac cctgcccctg aagacgaacc ttatataatt tttgtttaca tattcattat
    16081 acatatctat tcaaaaaacg caacatctaa cacttataaa aagtaagtgt tcattttgag
    16141 tggttcagca aactgctgac ttcttttttg ttcagttcac ggtaatcccc aggacgtagg
    16201 ccttgtaaag tcagatctcc gtatttttca cgttttagtt tttgcacagg aagaccaact
    16261 gcttgaagca tatttttcac ttgatgatta cgtccttcgt ggatcgtcaa ttccacgata
    16321 ctgtggtttg tcttaggatc cactgataaa atttggaatt tagctggaga tgtttttcgt
    16381 ccttcgatct ttattccttt tgtcaaaggt gcaagcatcg attttgtagc gatccctttt
    16441 acctttgcaa cgtaaacttt atccacttca tgttttggat gtgtcaggcg ctgagcaaaa
    16501 tctccatcat ttgtcagtag caagatcccc gaagtatcgt aatccagtcg acctacagga
    16561 tagatacgtt cttttaccat cggcaaaaga tccgtaacaa cttttcttcc tttgtcatct
    16621 gcaacagcag aaataactcc tttaggtttg tacaataaat agtaaccgta ttcttcttga
    16681 taaattggga cttcatccac ttccacagtg tcatgtttcc caacttttat ccctaattcc
    16741 cttacaactt gtccgtttac ttttacacgt cctgcaagga tgaattcttc tgcttttcga
    16801 cgagaagtga tgccagcgtg ggcaattact ttctgcaatc tctccattac aattattctc
    16861 ctttattcat tccatcaaag aatagatctg gtgacacgtc ttcttcaagt gaaatttcca
    16921 tttcttgtgt atcaggcagt tcttctaatg atttcaaacc aaaataatct aagaagtagc
    16981 cagttgttcc atataatatc ggccgacctg gtccttctac tctacctttt tcttcaatca
    17041 gtttatgggc agctagacgc tgtaccgctc ctgaaacctg aactcctcga atctgctcga
    17101 tttcagctct tgtgattggc tgtttataag cgatgattgc taaggtttcg acggcggctt
    17161 gagataatgt gtttgatgtc ccttgcgcat atcgcttaag taagggagcc agctcttttt
    17221 tagtcgttaa tacataatgg ctttccgttt caaaaatatg caaagctgag tgcgagtttt
    17281 gagtgtaaga ttcttttaat tctttcacta aacttgtgac ttctgcttcg ctgagattta
    17341 acagtccgct taattcttca ttactgatcc cttcctcgcc aacaataaaa agaagggctt
    17401 caagttcact taatttcgtc atgttcggta tctcctactg ctggataaag cataattgat
    17461 tcatagtttt ctttttgttg cgcaatgatc tgcccttttt tcatcaattc tagcaaagcc
    17521 ataaaagtag tgacaacttc acttttagaa ggtgactcaa aaaaagaatc gaaagtacag
    17581 ccatgcgcat ttctttttat acgctcttcg ataaatacca ttcgttcttc gatcgttgtg
    17641 tcatcgggcg tgatcgtttt ttccactttt tgagaaaatt tcttacgttc taagattttc
    17701 tgcatggcac ggatcaaatc gatttttttg acttgtcctc gcttcaacgg cttttcagca
    17761 tccgctaacc catcgatgtt cataggttct tttgtgtaat aaagacttcg ttcctctgct
    17821 ttttctgtca gtctttcagc tgcatattta tatttacggt attctaaaag ctgagtgacc
    17881 aattcttctc gaggatcttc ttcccataat tcttcatcgt ctgtgacgaa ttcttggaca
    17941 ggaagcaatg tcttgctttt gattgccatc aatgtagcag ccatcactaa gtattctcct
    18001 gcaacagcta gctcgagtgt tttcattgta tggatataat tcatatattg ctccgtgatc
    18061 gtagcgatcg gtatatcata tatatcgatt tccatttgct gaatcagatg aagcagcaga
    18121 tcgagaggac cctcgaatac atctaattta atattgatct ccgtcaactc attcactctt
    18181 tcttcttttt ctttgctagc cattttccaa tgtaaggctc tgtgatttca gttgcacgga
    18241 tggagacatc cgggtacttt tcctgtaatt catctaacat ttgaaagccc atattctcac
    18301 cgcgataaga cggattcaaa gaaatgtcat ggatgatcag ctgatcgttc gttgcccagt
    18361 aaataccaat aatcccttga atgttggttg aaccttctgg cgtaaagaaa aaaagttcat
    18421 aatcgtcttc agattcgtac gtatcaatct ccttcaacaa agaagtttta cctgtcagtt
    18481 tcttatggaa actcaatagt cccatagcaa ttttacggtt ttctttccgg taatgtgtta
    18541 acatcttctc accttcctat gactaagccc ttggaaaatg ctgcttataa acatccgtca
    18601 ttcttttctt cgtgatatgt gtataaatct gagtcgtaga gatatccgcg tgacctaaca
    18661 attcctgtac tgtccgcaaa tcagctccat tttctagcag atgtgtggca aagctatgcc
    18721 gcagcgtatg tggtgttact tctttgtaaa tcccagcctc tcgtactaac tgcttcagat
    18781 ttttccagat tccttgccga gaaagacctt tcccatgatt attgacaaat acatgcattt
    18841 cagatgcgtc ctttacaagt aatggacgtg cttcgtctaa gtagcgttcc agccattgga
    18901 tcgcataatc acctaaagga atgatccgct ctttatctcc ttttccaact gtctgtacca
    18961 gtccaagaga aagatgaaga tctcccaatt tcaatccaat caattcactg acgcgcatcc
    19021 cagtagcata catgacttcc aagattgcac gatctcttat ccctaacgtt tttgtcgtat
    19081 caggtgcttc aatcagcttt tctacttctg tcagagtcaa tgtacttggt aatttctgtg
    19141 ctttcttcgg cgtatcgata tgttgcatcg gatcatgatc agtgatacgc tcttgccgta
    19201 aaaactgatg gaatcttctg agacttgaga tcatccgagt aacagttgct gtcgcttttt
    19261 tttcttcatg caacttctcc agaaaacgga tgactaaaaa gcgatcgaca tcctgccatg
    19321 aagcaatttt ctgctcctgt agaaaatgca agtactgttc caaatcacgt tcatagcttt
    19381 gtcgtgtatt ggcggacaat ccccgttcaa tattcaagta gtggagataa tcgttgattt
    19441 gctctttcat aataatcccc ctcatgcctc tctatcatat cagataccgc ttcattctga
    19501 tagtcttttt ccataatctg agcaaagaaa aagccgtcta gacactcaga cggactggtt
    19561 tcttttttct ttttcatagc attcctgaca gattccatgg aacgttagcc gatgatcttt
    19621 tactaaaaaa tgataacgtt cttctactac ttgctccact tcaagtaaaa gatcctcttc
    19681 tacttcctcg atcgtgccgc agttcaagca tagtaaatga tgatggaaat gtttggcgcc
    19741 ttcttttctc aaatcataac gggctaatcc atcattaaaa cttactttat cgacaatttt
    19801 caattctgtc aagatttcaa gggttcgata aacagtagca agtccaattt ccggactctt
    19861 ttttttcact aaaaagaaga tttcttctgc agataaatgc tctttctcat tttccaaaag
    19921 cacaagcaga gtagcttctc tttgcggtgt cagcttaaac cccgcttcat gtagctgctg
    19981 ttttgttttt ttcatcgccg aaatagcatt catgaccatt tactcaaccc caacaattta
    20041 taataattac aaataaaaaa agatataaca ctatgttaat taaaattatt ataagctagt
    20101 taagaaaaac atgcaaggga ttctcaatta gattttttga ctagttttgt cacaccgttt
    20161 tcttgtgtaa tcaatccttg tttcaaaaga ttacctaatg cgcgcttaaa tgctcctttg
    20221 ctgataccaa aagctttcat gatttcttct ggatccgatt tatctgtaaa gttgatttgc
    20281 tgatctgcag aacgttctaa aatggttaaa atcatttgtg catcatctga tatagcttca
    20341 tatgctcttg gcttcaatga aagattcagt acaccgtctg gtcggacacc aatcactcga
    20401 ccttttatct gctcgcctag acgaggttca ttatatcgtt cagaaggatg gataaaccca
    20461 agatagaaat cttccgttaa aacgtacgta cctgttaatt tcaagcggta tgctgttcct
    20521 atcacatctt tgtttttcat ttcttctgtt ccatatttgc ttaaagattt gaatattttt
    20581 tcatctgcta aactgcccca aatacggtct tttgcatcaa ctctaaggga aatcatcaag
    20641 cgatcccctt ttttaggcca tagctctgtc attgtcggca attcatcaag agatacgaca
    20701 aagtctttat ctggaagacc gatatcgaca aacgcaccta aatcttttcg tgtagcagta
    20761 acgattccaa aagcgtaatg accgatacgg cttttaggaa tttgtgtagt gatccgattt
    20821 tcatgttttt gattttggta accgaatcct tcaactgctt caccgatttt gtgttcacct
    20881 tctgatttgc ttaagccaaa ggtttgtccg tttttttgga caaagtagtt tttttcattt
    20941 tcatcaataa taatacctgt aaatatagtt gctaataaat cgttcatttt tttctccctc
    21001 tatagtgaaa ggttttctta atacatttct ttgctatcat aacataatgt tatctacttg
    21061 aatagctgag ccttggtttg gaaaggtgaa aaaaggagta tgacaacagt tgtgtcatac
    21121 tccccttttt cgaataaacg gtgttaaacg gcaggctcac agcctctttc atttgcctaa
    21181 aattaattgc tcccatttcc tccgaaccat ccagttttac agttgatggt tacgatgtaa
    21241 aatggcaaag cactttctcc aatgcctttc atcaatgcag attttgttga agtggcatat
    21301 agattataat agccttcccc attttcgatt ctggcttttt ctaatctgta acctccttca
    21361 acgatatatc cacgttggat acatgtagca atcactttgc tttggacacc tggtgcccac
    21421 gtccatgctg gattagatgc atcggcaata tcacttgctc tggcagattt gattggctga
    21481 ttcgctgagt ttgaagagga aggggtcgag gatgccgctt cttgctgtgc tgcttgtgcg
    21541 accgcagctt gttgagcggc ttgagctgca gctgctgctt gagcggcttg ttttgcttgt
    21601 tcttcagctg cttttttcgc ttcttctgct tttttctttt cctcttcttc ttttttctct
    21661 ttatcagtga gcatcttatc tacttgtttc aattgttcat tcaactgagc agatagatct
    21721 gtatttttca ctttttctac tgcttctttt gccgtcttgt attggtcgcg tgttgctgaa
    21781 tccactactt ttccgtcttt aaagactata gctgtttttt ctttagctgt ttgcaattca
    21841 gcatattgat ttttagcttc tgtttgtgct tgttgaatca attttccaaa atctgtgtta
    21901 tccgtttcga ttgcttggat ctctttatct gctttcaact tgatgtcatc tgctagatga
    21961 tcatcgacga tggcaggtgc tatgaaccac tcattcactt tttggatatc tcggatctta
    22021 gattggatat cttggtaagt tgtttctaac tctgaatatc ctttttcatt cttaagactg
    22081 gataaatcat tttttagttt tgataaatct tgatgaatca tatctgcacg aataaattga
    22141 tggtgatcat ctgtataaaa ggcagcaagt ttctcatgaa gttcttccat ttgttgctgt
    22201 ctttttgctt ctgctgctac ttcggcttct actttttgat gatggtcata ataagcccag
    22261 cttcctccac cgagtagaag tactgctgct aaaacgagat aaggtacttt ttttgatttt
    22321 ttcttttgcg ctttatctgg atctgttttt tctaagtttg attcttgatg tgttttttca
    22381 gtatctggca cgattgttat tgatttcgct tctgcttcaa acagcttagg ctggttctct
    22441 tctttttcta tttttgcttc aagatcagta ccctctttgc ttacagattg attttcagca
    22501 tcggattcac tatttatttc atcgggctct gttgactttt tgtctgtgtt ttcgagtatt
    22561 tcttttttct ctgcttccgg cagtttattc gttttttcct tttctaattg tttttcagta
    22621 aatacttcag ttttttctgt gatatccgtt tttacgtctt ttatttttac tgtttcttta
    22681 cctgtggcgt tttctctatc agagtctttt tcagtttctt gttccttttc tggctctact
    22741 ttgttttcct gtgcaatttt ttcactgatc attttgagca gctctttcgc gtgctcttct
    22801 tttgtatctt cacgatgtgc tttgatataa gcggatagta tcgaattttc ttcctcatta
    22861 tcgacgattt ctttcagttc agctactctt cttttttgtt ttgattcaag cgtttcttct
    22921 tgattctttc ctgattcttc cgaagtctca tgaacagttg ctttcttctg ttcatttttc
    22981 tctatattag ttacttgatc gtgagcaggt ggttcttcgt cttctggttc tgctttttcg
    23041 aataattcca ttacagattc tagaggtaaa tctttcaatt ccgaccattc gattggatcg
    23101 tttaattctg tatcaggaaa gactgcatct tcagttgatt tatcctgcat agctgcatct
    23161 gtatttgttt cttcaattga ttcttttatt tgctgatctt ctgcagttat ttgatgaccg
    23221 cagtctggac agatagtatt ctgctccatt tttttcgatc cgcaatttgg acattttttc
    23281 atcacttagc gatcggctcc tttactaggt ttacgctacc atttaatcta tcatattcta
    23341 tacgtcacgc caatagctta tttttaggat ttacttaaaa ataatgaatg aatttccttc
    23401 ctatagaaaa aaaagcttga gactgcgtag tctcaagctt tttttctttt aaaataaacc
    23461 aaacagtttt actgatttct cttctggtca atagtccacg cttattctaa gaaatctttt
    23521 aattgttttg aacgagaagg atggcgcaat tttcttaatg ctttagcctc gatctgacga
    23581 atacgttccc gagtaacacc aaatactttc cctacttctt ccaatgttct cgtccggcca
    23641 tcatctaaac caaaacgtaa gcgaaggaca ttctcttccc gatcagtcaa tgtatctagt
    23701 acatcttcca attgttcttt tagtaactca taagctgcgt gttctgctgg acttgttgct
    23761 tcctggtctt ctatgaaatc acctaagtga gagtcatctt cttcaccgat tggcgtttca
    23821 agggaaacag gttcttgcgc gattttcaag atttctcgga ctttttctgt tggaagatcc
    23881 atttccgcac cgatttcttc tggcgtaggt tctcttccaa ggtcttgcag caattgacgt
    23941 tggatacgta tcaatttatt aattgtttca accatatgaa ctggaatacg gatcgtacgt
    24001 gcttggtcag cgattgctcg agtgatggct tgacgaatcc accatgtagc ataggttgaa
    24061 aacttaaatc ctttgcggta gtcaaatttt tcaactgcct tcatcagtcc catgtttcct
    24121 tcttggatca agtcaaggaa ctgcatgcct cgtcctacat aacgtttagc gatacttact
    24181 actaaacgaa ggtttgcttc tgccagacgc tgtttcgctt cttggtcgcc ttcttcgatt
    24241 ttcaatgcta acgctacttc ttcttccgca gttaaaaggg agacacggcc aatttctttc
    24301 agatacatac gaaccgggtc attgattttt acaccggttg gcgcagaaag atcttctgtt
    24361 tttgcttgtt cagctttttt ctcagcactc ttcaagctgt gaattgatgg atcaccattt
    24421 tcatccacca cactgatacc tgcgtcttca atcttttgga tcaatttgtc catttcatct
    24481 gcattcaaag tgaatggtgt agcaagctga ttggataaat catcatatac aacttgtcgt
    24541 ttgggtttgt tttctttgat gaaagctgct actgctgctt catacgtttt tttatctgtt
    24601 ccatttgcca taaaagaagg ccccccttga gtagctattt ggcttgtttt aactgtttcg
    24661 ttaaattgat gatttcaatc gtcaattcaa gctcaagctg tttgtttcca gttcgtctgg
    24721 cttcttgctg catttgtttt tttaatgtta tttcatcagc taagccagat ttgctgatca
    24781 catctagcaa gtcttggatt tctcgtggcg aactttcttc tgccaccggt aaatattcga
    24841 tttccaccac caaccgcctt aaattttcat cttgcaaaaa gtctaaaaac tctgcaaggt
    24901 tgaattcata atgttgtgag acatatgcat cgaataaaaa ataaacttct gcatatgcat
    24961 catgaataaa ctgaaattct cgttctttta aaatattacg gacagaaact tctttaaatg
    25021 cacgatataa tagaatctgc tctgcctttt ctacttgcgt caaaggtctc tttttccgtg
    25081 cagtttcttg tctcgtaacc tgagtgtgtt gactttcctg aggttcttga cgattttgct
    25141 gatttgtcct tcgaagatcg cgcagttgtt tttgtatcgt ctctctgccg atctgaaact
    25201 ctgttgacag ttgagataga tacatatctt gttcgattgg tgaaacaact cggctaagtt
    25261 caactagtaa ttcttcgagg tattcgatct tgtctttttc attatctaaa tttttccctt
    25321 gttttaaata acgtgattta aaagtaaaga ctgtttcgcg cccatgagcc actaattctt
    25381 ggaaagatgc ttctccatac ttacggagat attcatcagg atcaagcttt tctggaacga
    25441 ctacgacaga aagtgctaat cgactgtttt gccgaagcaa ttcaatccct cgattggttg
    25501 cttcaaaacc tgcgttgtct ccgtcatagc aaaagaccaa ttctttcgtc agcttttcca
    25561 tttgttggat ctgttgagct gttagacttg tccccataga agctaatcca gttttgatac
    25621 cagcctgcca tgcagcaatc acatccataa acccttcgaa caacaaaatt tctccgtttt
    25681 tccggatatc gcttcttgct ttatcaagat taaataaaac ttgtctttta ttgaacagtt
    25741 ctgtttctgg actattcaag tatttgggct gatctttttc ctgccctttt tcaggtgcaa
    25801 gccagcgtcc tgaaaaaccg atcgtctggc cttgagaatt acgaagtgga aacatcactc
    25861 tttgataaaa acgatcagac atacggccat catcatgcgt gacaaacaat ccagagcgtt
    25921 ctaacaattc atttgaaatt gattcattct tgaatacttg ctgaagaaaa gaacgctcat
    25981 taggtgcaaa acctatgttg aattcttcaa ttaattctaa agacaaccca cgactttgca
    26041 aatattctaa agctggctgt ccagcttttg tatgcaatag catgtgatga tagatttccg
    26101 ctgctttttc atgagcagca atcagtttcc ccgtagcaga ttcaggattt tggacagcta
    26161 tagtacgctg acgccattga tcttctaacg gtatctgttc gaagtctgcc acttttacca
    26221 ctgcttctgg aaaacttaga ccttctagtt cttgaagaaa agtaaacacg tttccgcctt
    26281 taccacaacc aaagcaatga aaaatctgct tgtcttctgc aacagaaaaa gacggtgtac
    26341 gttcttcatg aaaaggacac agccccaagt aatttttacc agactttttc aactggacat
    26401 attgtccaat cacctcaacg atattcgttt gactgcgtac tgtttcgata acctcttgag
    26461 gaatccgttg agccattttt tcaccccctg ctctattgat atcttttggg tttaacagaa
    26521 gatatttcag gagaataacc ggtaaaaaat cgcactaact gaaatcagtg cgattttaaa
    26581 ggacacaatt atacatgttt gattgtatca tatttcattg ctttttcaag tataacacat
    26641 ttctatctca ttaagcatca atttgctact cttttcagta actgattttg aatatcagcc
    26701 ttccagtaca atactcgaag aacaatattt acgagcatga atacaaagaa gtatcctacg
    26761 ctctctccca accctaagtt tacttccaaa attccatgga acagcattgc agctacatat
    26821 atccctacga tcgtcgttac tgctaggaag atgcgcaatg ggttgaaggg ataacaagct
    26881 tttacaactg ccatgcaact gatcccaatc agcaagtaat acatcaaagt agtagtttca
    26941 gcatttcccc atgcgaatgt ttttccaagt agatacaccg caatgatatt cactactaca
    27001 agcaaggcat ttggtaaagc attaataagt gctgtaggca aataacggta agtgattttt
    27061 cttttatctt gttcaaaaga taaaaagaag gaaggatacc cttcaatcgc taaatcaatc
    27121 agcgtgattt ggatagggat aaacggaaat ccaattgctg taacggcaca tataatcgat
    27181 aaaataaatg aataaatcgt tttgataaaa aagatgcctg agactttcgt cacattgttg
    27241 accactcggc gtccttcaaa caggacttct ggcaatgtag taaaatcaga gtccaacaat
    27301 accagattcg caatctgacg tgttgctcca tcaccttctg ccatagcaat gctgcaatct
    27361 gcttctctta acgccaaaac atcattcaca ccgtcgcctg tcattgcaac cgttctgccg
    27421 ctttctttca attcatttac cagcaatttc ttttgctgcg gactcactcg tccaaaaacc
    27481 gtatagcgat gagcagcttc tcgcacttcc atttcttcag taatttgaga aagatcgaca
    27541 tacgcatcat aattcggtaa tcctgcacgt ctagcgatat tggagacagt aaaaggattg
    27601 tctccagaaa tcactttcag atccacacct tcctcatgaa gataagctag tgtttcttga
    27661 gcgttttttc ggattggatc atcgatttca aacagagcaa ccggctcaac aaatgctggt
    27721 ttttcttcgt tcaattgctg atttggagcg atccccaaca taagtacgcg atagccattc
    27781 gcttgggctg tttttagact gtccggaagc cgatcttctt ccaccaaacg ttcaggcgct
    27841 cctacgtaca cgactcccag ttctggaaat tccatcgcgc cccatttgcg atcagaagaa
    27901 aatgcgactt tgtttgtcac atcataccga ttagaaagct caaaataatc tctcatagcc
    27961 cgcatagtga tgttgttatc actgctttct gccagatacg tccccataat ttctgggatg
    28021 gctttctcgt acagcggatg tagtgcttct acccgctgga tactcatttt cccttcagta
    28081 atggtccctg ttttatccaa gcataatgta tcgacatggg ccagcgtttc aattgaatac
    28141 atgtcttgaa caaggattcg tttttttgcc agtttggtta cccctgtcgt taatgcaata
    28201 cttattagca ataccaaacc ctttggaagc atgcctaaca aagctgctgc agatgcaata
    28261 acagaaattt tgatagaagc atcgcggatg aacagtgctt ccaaaaatag tatgatcccc
    28321 aaaggaataa tcacgaaact agtgaatttg gatactttgc gaatcgaatc tacaagttca
    28381 gaacgaatag ctttgtgagt ctttgcctcg ctagtcaagc ggacagcata attatctgca
    28441 cctactcgga taacttcagc catgacagaa ccgcttgtca aaaagcttcc agaaagcaat
    28501 tcagctccag tttctttgac aatcaaatca gattcgcctg tcaaaagagc ttcatttgct
    28561 tctgcccgtc cagatataac ctgtaaatcg gctggtatct gttctcctgc tccgattttt
    28621 accaaatctc ctaataccag ctctttagta gaaatcgatt gttctttacc gtcccggatc
    28681 actagtactt ctgattggga aacaatcgat aatttccgta caagatttct tgcatgtatt
    28741 tcttgataaa ttccaataac gatattgacg acaataattg ctaaatacgc catgttggaa
    28801 tacgcaccta caaataacag acaaatccca ataccaaagt tcagaaaatt gaataacgtc
    28861 aatatattat cgctgaatat ttgttttgta ctttttgatg catcttcctg gtagtcattt
    28921 tgctggccag aagccatttt ctgaactacc tcttgctgtg taagtccatt cattttcttt
    28981 ttctccattt tccgccaact ttcaaaaata atcacgtgtt taagtctagc gtgttccaag
    29041 attaaaaaca acttgttttt ataaaattta tagaaaaaca cacgaatgat tttacaaaaa
    29101 agatgccaac ctttttgttt gaatcacccg tgtgctgttt ttattatcaa tctatcttta
    29161 cttatattgt tcctccaaac ggctcatcca ccaacctagt gctgtaccgg ctataaaaag
    29221 aacaggacaa gctagtaccc cagcaactcc caatcccgcg taatcggtag gaatgatcat
    29281 aatcgttgaa gcaaaaacta cacctaaaat gaaatggaat agcttgctat atgcctttga
    29341 gaaaatgtaa tccatgattt ttgacaatcc aagaacacaa agaatcccac caattccgat
    29401 cggcacaatc acttcaagtc gtacttcttt aaatccgtca gccatcgctt tatacaatcc
    29461 catatacacc aaaaaattag aagggctcaa tcctgggacg atcataccca aaccaatcaa
    29521 tccgccggca atcagccatg ttccaaaatt ctgatcgact tgcccgtcaa ataattgagc
    29581 gccgtataat aaaaacaaat aagccagaac aaaagtaaca accatgatga tcacatcaga
    29641 agtatctctt ccttttttcc ctgcttcttt ccataacgca ggaacagttc cagcgataca
    29701 tccgacaaaa aaccataata tcgttgtttc atacgcacct aataaaaaac tgactaaaaa
    29761 agaaagtaga aagatgcctg tcactccgcc tagaccaaca ggcagaaaaa acaaaacatt
    29821 ttctttgaaa ttttttgtaa ggtgggctaa aaaagaaatc agccgctcat acatgccaaa
    29881 gacagctgct aatgcaccac cgctgactcc tggcaagata aatcctgaac cgataaacat
    29941 tcccttcaca aaccgtaaca tccagtcttt ggttgtgtac cccacttctt gattttccat
    30001 tttttgcctt ttttccacta tttgcgtact ccttctttca tttaatttta ttcatgattg
    30061 aacatttcct gctattttac ttaaagactt tttcataggt ctctattatt ttttcattca
    30121 ttttgacaat atcaggataa aacatgttac ctccattatg atagagatag ccgccattgt
    30181 aaagcaagga ctggatccgc caatatcggt attgtttccc ttcctcattt cctaaaagtg
    30241 ggctcagcac atctttagaa tacgcttctg ctaattctac tgtgttttct ccgccatgat
    30301 tttttacata ggcaatataa tctttcccaa aattatatgc ttggacagct gtccataaat
    30361 cgcatccttg tttctttgct tctactatca tttccgccaa atatttgaca ccttgatcaa
    30421 tactgtcagc tggattatca atgatctcag cttctccatg cagactttcc gagctctgca
    30481 tgagatctgt cccttttcct tttgattcgg tcaatattat cgccttgatc aaattctcgt
    30541 agttttccat atgataattt tttgcagctg ttgttatttc tatttgatag ctttccactc
    30601 gttttaccga acgataagtt cttcctcata aaaacaacac cgcaccaata accgtcagaa
    30661 tgatcatgta aaaaagaata cggataatag ataatcgttt tcgcttcatt tcatcaccta
    30721 gttattttga catctttttt tatcttacta tttctttatc ttcttggcta tttcttcctt
    30781 gatttctgtg tacgccttaa gaaaaaatga attttcctgt attttttgac atcttacgaa
    30841 aatgatcgtt gtttttcagt aaaaacaatt gcccaatgac tgatataatc gttatacttt
    30901 acacagtagg tgattatgtg aaaaaagaaa agaaatatgc aaaaatgcca gatgggagcg
    30961 aaatttacta tgaaaagagc ggtcaaggct tccctctctt tttactgcat ggcaatgacg
    31021 gcagcggccg ctttttttca gaacaggtcc ctgtactcga acgctactat accgtgtatc
    31081 tagtagatag ccgaggacat ggtcgttcga caaacgaagc atctatgttg aattttcagt
    31141 taatggccga ggatctgaat acgatcatgt tgctggaaaa aatcgatcag gcagattttc
    31201 ttggatttag tgatggagca aatctagcac tggtatttgc cagcagcttc cctaaaaaag
    31261 ttcatcgatt gattttaaat tctggaaaca cgcttgttaa aggcgttcgt ttttctgcca
    31321 gagtcatcag taatattcat tatgcatggg tatggttact ctctttattt cgcccaagtc
    31381 ttcgcaaaaa tcttttagtt atcaaacttt tgctgcatga catcgggctt acagaaaatg
    31441 atttaaaaaa aatcaactcc cccactttga tcatcgtggg aaaaaaagat gtaatcaagc
    31501 taaaacattc tttgtatata gctaaaacta taccaaaagc ttcctttgtg cttgtgaaag
    31561 aacaaggaca tgaattagct agaaaagatc ctgaacgctt caatcgagaa gttcttcaat
    31621 ttctttctga aacataacta ttaggaatag aaggtgattt atttgttaaa aaataccata
    31681 caatggctga aaaaccacct aggactgttc aaaacaatct ttttgatttc tgtcattgtc
    31741 attattgtcg gtgaattgat gtccatcggt aaaactctat ctatccagca attaggagaa
    31801 acgtttgcca ctatacctgt atggaaaagc ggactaatgc tattgattgg tcttatctct
    31861 gtgttaccta tggttggtta tgatattatt ttgaatcgga tgcttgaaca aaagcagaat
    31921 cctcgttacc tgtttgagac aagctggctg atcaatacga tcaacaatat tgccggtttc
    31981 ggcgggtttg ttagtgtggg gcttcgctct gaactatatg gacaaaagaa agagagcaga
    32041 aacgtgatcc aagcattatc gaaagttttc ttgtttttga tggctggact ttctatttac
    32101 agtctgcttt cttttttact tgtagtcttc acgccagttg ctcctttttt gaagcaatat
    32161 tggatatggt tgatcggcgg cggtctatat tttcctgtcg tctttttatt tactactttc
    32221 aaaaagaaag gattccttgg tggtacctca cttaaaactc aaggacagct attgctagtt
    32281 tcattgttgg aatggaccgg tgtcctgttt agtttccttt ctgttggtta tttaatggaa
    32341 atccggattg atctgtggca aacaattcca ttattcattg ctgcttcagt gataggaatc
    32401 gtgtctatga ttccaggaga aattgggagt ttcgatgtaa tgatgattat cgggttgtcc
    32461 gctattggtg tgccaagaga aatagtcgtt gtgtggatct tgctctatcg cctgttctac
    32521 tacatcattc cgtttttgat tggaatcgtc tttttcttca aaaatatcgg ttccactttt
    32581 gatcagcgtt attctggtat ccctaaacaa ttagcaacag aaattgcgca taaaatcgtg
    32641 gttgtcttat tatacttttc tggaatcatg ctagtacttt ctgccactat cccgcaagct
    32701 tttacagagt ttcgctggct tcatagtttg aacccattga aatttcattt tattatccaa
    32761 tttcctagta tactattggg atttctttta atcattatgg gcagagggat cgcagcacgt
    32821 gtgaaacgag catatttgcc tacaatcttc ttgattgttc tagctttact ttatgtttta
    32881 ttaagtgatt ttagtttcac accggtggtt ttcttgtcta ttctgcttct gatcattctt
    32941 gcttctaaaa acgaattatt tcgggaacaa ttgatctatt catgggagtg gcgtacgatc
    33001 gatggaatca ttattggtgc actgtccttg ctttacatcg ttattggggt atacaatctg
    33061 ccggatttcc ctcatcggcg tcaccatttt atttcctttt tcttatttcc ttctgaaaag
    33121 atttggtttt cgggattgtt ggccatcatc gctgttagtt tcatgatcgt tctatttgtt
    33181 catttccttc aaggagaaaa gaaacagatt ggcgaagcct ttaatgaaga aaaggccctg
    33241 aagatcctta caacttatgg aggaaactcc gatagtcaat tgatcttctt aaaagataag
    33301 cggatgtttg cctatgaaaa agacggtgaa ccaactgttc ttctccaatt cgcttgcttc
    33361 aataataaat gtattgtaat gggtgatcct tctggtaaga aagaagattt tccagaagca
    33421 atcgaagctt ttatcgaaga aacagatcga ctatgctatt taccagtttt ctacgaaaca
    33481 agcgaagaga ttgttatgat tttgcatgaa ttcggctacg atttcattaa gatgggggaa
    33541 gaagcttatg tagacctgaa tagttttaca acttcaggga aaaaaatgaa gggcactcgt
    33601 gctgtcttga atcggatcga acgagaagga tttacatttg atgtcttaca accaccattt
    33661 tctactgagc aaatgagtac tttcaaaaat atctctgata attggttggg ttcacgaaag
    33721 gaaaaagggt tttctttagg ctttttctct gaagattatc tacaaagagc gcctattgca
    33781 gttgtcaaaa atacccaaga agaaattgtc gcttttgcaa cgatcatgcc tacttacacg
    33841 aacaataaag taggaacgat tgatctgatg cgatatgatt ctaaaaaagc accttctggc
    33901 agtatggatt tcttgttctt gcatttgttt gcctatatga aagaagaaca tatccaatgg
    33961 ttcaatttag ggatggcccc tctttcaaat gtcggaactt ccagaaagag ttttttacag
    34021 gaaaggattg catacttggt ttacgagttt ggttctcatt tttattcttt ccatggatta
    34081 agagaatata aaagcaagta cgctacaaac tgggtctcac gttatactct atattctaga
    34141 gatagttgga ttgcatatgt tatgattgct ttgctgatta ttgataatgc gccagttgag
    34201 cagacacaag gtagaataag tggtttgaaa aaatggatac gaagaaagta ttaaaaactg
    34261 cataccgata gatgaacact ctcatgatga ataaaagaga ctgaagtaaa acgaaagttc
    34321 atgcttctac aatctcttct tatacaattg aagaacaaag agcggtccaa acagaaatcc
    34381 tgtttggacc gctcttttat tttaaacatt tttcattacc aaaatattcg agtcgcgttt
    34441 cttatgcttc gatctctgta acgatacctg aacctactgt ccgtccgcct tcacgaattg
    34501 agaatgtcgt tccgttttca acagcgattg gatggatcaa gtcaacatca atcgtcacgt
    34561 tgtcaccagg catgaccatt tctgtatctt ctggcaatgt gattgttcct gtaacatcag
    34621 ttgtgcggaa gtagaactgt ggacgatagt tgttgaagaa tggagtatga cgtccacctt
    34681 cttcttttgt caacacgtac acttctgctt tgaattttgt atgtggagta atggaacctg
    34741 gtttagcaag tacttgtcca cgttcgatat cgtcacgttg gatcccccgt aacaacacgc
    34801 ctacgttatc cccagcttcc ccgtaatcta acgttttacg gaacatttct acacctgtta
    34861 caactgcttt ttgtgtttca ggtttgatcc ctacgatctc tacctcatca ccgacacgaa
    34921 cagcaccacg atcaatacga cctgaggcaa cagttcctcg acctgtaatt gagaagacgt
    34981 cttccactgg caatagtaat ggtttatctg tatcacgttc tggtgttggg atatattcat
    35041 ctactgtatc catcaattcc ataatagcag cttcagcatc tggatcgcct tgcaatgctt
    35101 ttaatgcgga acctttgatc acaggagtgt catcgcctgg gaaaccatat tcgctcaata
    35161 actcgcgaac ttccatttct accaaatcga tcaattcttc atcatcgact aaatcaactt
    35221 tgttcaagaa aacaatcagg tattttacac caacttggcg tgacaataaa atgtgttcac
    35281 gtgtttgagg catcggaccg tcagttgcag aaacaactaa gattgcacca tccatttgtg
    35341 ctgcccctgt aatcatgttt ttcacatagt ccgcgtgtcc tggtgcatca atatgcgcgt
    35401 agtggcgttt ttctgtttca tattctacgt gtgcggtatt gatcgtaatc ccacgttcac
    35461 gttcttctgg agctgcatca atactagcat agtcttgagg atttgctagg ccttttttgc
    35521 ctaatactgt agtgatcgca gcagttaaag tagttttccc atggtcaacg tgtccaatcg
    35581 taccaatgtt aacgtgtggt ttacttctgt cataatgttc ttttgccata atttacaaac
    35641 ctcctaaata atatagatca ctgaaaaatt tcagctctca cctttttatt atagtctttt
    35701 tttgactaaa tcaaaaagaa tacgtccgac ttactttttg taagattcga actaagctta
    35761 ttatacgtca atattggtca aagtcaacta agagcactcg tctgtcttat acgcgaaaaa
    35821 agtacctttt ataaataaaa aaatgtgttt tttgagaaaa acttcaagat agtccttaac
    35881 tttcttttga agcaataaga acaaaatgag gaaaagttta aaattcagct gttgccaaca
    35941 actttcaata gacgaaatct tctatttcgt taataataag gaaagaggtg aagtacatga
    36001 aaaaattaat tggcgtactt gtcgttttag gcatatttct cggcggaagt tttgcagctt
    36061 atcattattt ttacggcggc gaagcttatt atacaaaaat cacgacgaat ggcgaaatgt
    36121 cagctaccca agcagataac ggagagaaat tcacgactta tacctacaag caagcggctt
    36181 ataataaaga tggtgaaaaa aaacaggtga cgcttcgcga agaaagagaa catccattaa
    36241 agatgaatgc gtatcttaaa ctcaaagtca atcctcgtaa aggtgtatta agctgggaag
    36301 aaataaaggc ttctgaagtg cctaaaaatg cggcagaaaa aatcgataat tagtaaatgg
    36361 tcttaaaatt ttattagata aaaagaggct gggacagaag cgtttaact
//
LOCUS       DADGHT010000018        36269 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.018, whole genome shotgun sequence.
ACCESSION   DADGHT010000018 DADGHT010000000
VERSION     DADGHT010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.018"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(326..1603)
                     /locus_tag="JX887_000787"
     CDS             complement(326..1603)
                     /locus_tag="JX887_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256795.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(1682..2326)
                     /gene="pcp"
                     /locus_tag="JX887_000788"
     CDS             complement(1682..2326)
                     /gene="pcp"
                     /locus_tag="JX887_000788"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAX1256796.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(2525..3469)
                     /locus_tag="JX887_000789"
     CDS             complement(2525..3469)
                     /locus_tag="JX887_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAX1256797.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(3471..4157)
                     /locus_tag="JX887_000790"
     CDS             complement(3471..4157)
                     /locus_tag="JX887_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAX1256798.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            4631..4951
                     /locus_tag="JX887_000791"
     CDS             4631..4951
                     /locus_tag="JX887_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAX1256799.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            5105..6010
                     /locus_tag="JX887_000792"
     CDS             5105..6010
                     /locus_tag="JX887_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1256800.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            6007..6780
                     /locus_tag="JX887_000793"
     CDS             6007..6780
                     /locus_tag="JX887_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1256801.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(6961..8385)
                     /locus_tag="JX887_000794"
     CDS             complement(6961..8385)
                     /locus_tag="JX887_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1256802.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            8596..9042
                     /gene="nrdI"
                     /locus_tag="JX887_000795"
     CDS             8596..9042
                     /gene="nrdI"
                     /locus_tag="JX887_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAX1256803.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(9107..11089)
                     /locus_tag="JX887_000796"
     CDS             complement(9107..11089)
                     /locus_tag="JX887_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1256804.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(11103..11999)
                     /gene="murQ"
                     /locus_tag="JX887_000797"
     CDS             complement(11103..11999)
                     /gene="murQ"
                     /locus_tag="JX887_000797"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAX1256805.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(12002..13063)
                     /locus_tag="JX887_000798"
     CDS             complement(12002..13063)
                     /locus_tag="JX887_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAX1256806.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(13274..13801)
                     /locus_tag="JX887_000799"
     CDS             complement(13274..13801)
                     /locus_tag="JX887_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAX1256807.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(13868..15370)
                     /locus_tag="JX887_000800"
     CDS             complement(13868..15370)
                     /locus_tag="JX887_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAX1256808.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(15628..16749)
                     /locus_tag="JX887_000801"
     CDS             complement(15628..16749)
                     /locus_tag="JX887_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAX1256809.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            16875..17816
                     /locus_tag="JX887_000802"
     CDS             16875..17816
                     /locus_tag="JX887_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAX1256810.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(17966..18862)
                     /locus_tag="JX887_000803"
     CDS             complement(17966..18862)
                     /locus_tag="JX887_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAX1256811.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            19131..20471
                     /locus_tag="JX887_000804"
     CDS             19131..20471
                     /locus_tag="JX887_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1256812.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            20689..21132
                     /locus_tag="JX887_000805"
     CDS             20689..21132
                     /locus_tag="JX887_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAX1256813.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(21636..23054)
                     /gene="nhaC"
                     /locus_tag="JX887_000806"
     CDS             complement(21636..23054)
                     /gene="nhaC"
                     /locus_tag="JX887_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAX1256814.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(23457..24680)
                     /locus_tag="JX887_000807"
     CDS             complement(23457..24680)
                     /locus_tag="JX887_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAX1256815.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(24711..25550)
                     /locus_tag="JX887_000808"
     CDS             complement(24711..25550)
                     /locus_tag="JX887_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAX1256816.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(25567..26247)
                     /locus_tag="JX887_000809"
     CDS             complement(25567..26247)
                     /locus_tag="JX887_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1256817.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(26249..27322)
                     /locus_tag="JX887_000810"
     CDS             complement(26249..27322)
                     /locus_tag="JX887_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1256818.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     gene            complement(27969..28640)
                     /locus_tag="JX887_000811"
     CDS             complement(27969..28640)
                     /locus_tag="JX887_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAX1256819.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(28727..31405)
                     /gene="mgtA"
                     /locus_tag="JX887_000812"
     CDS             complement(28727..31405)
                     /gene="mgtA"
                     /locus_tag="JX887_000812"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAX1256820.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            32064..32501
                     /gene="ndk"
                     /locus_tag="JX887_000813"
     CDS             32064..32501
                     /gene="ndk"
                     /locus_tag="JX887_000813"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAX1256821.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(32523..33389)
                     /locus_tag="JX887_000814"
     CDS             complement(32523..33389)
                     /locus_tag="JX887_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1256822.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(33549..35642)
                     /locus_tag="JX887_000815"
     CDS             complement(33549..35642)
                     /locus_tag="JX887_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAX1256823.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT        10503 a         7613 c         6400 g        11753 t
ORIGIN      
        1 gtgtcgtctt tgtataggac actgtagctg tgtcccattg aaacatctaa tgcaagaatg
       61 taaggcattt gttttcctcc tttttaagtt ttgaaagaac tttactgctt catttcgatt
      121 ccaatttcct atacacgggc tcatggcccc aacatacgta aacctgattc taaaatgaca
      181 gtaaagaagt tcggtttttg atagggactc gtagtcctca aggctttgtt cgaactttct
      241 ttcactcttc actataatct aaaaatagaa aatagaggag aacatcattc gtcaatgatg
      301 ttcccctcta atcttagtat gttttttata gtaattcctt cagatacttt cttgcctcat
      361 cattgaaacg cagtgattct tctaacttct gataatattc caacgcttgt ttctgagctt
      421 cagtaaaacg ataatgtttt cctttccatt tgtcgattgt ctcttgcaca tttccagatt
      481 ggatatcttt cactactagt tgccattttt cttttgagac tgtacggtct ttcttatcag
      541 cagattgtat agcttctcgt tctttacgca atacttttaa aaaaccattt ctgactatcc
      601 gaggaatgct gtcgaagaac ccttctgtaa aaccatagcg acaatattgc ttccaaataa
      661 atagatagat ttttggttgg atgaatcgtt ggtttttcgc aaaatattcc atctgagcag
      721 tgacttctgg tgttcgttga cgttttgtct ttctcaacac ggaaataaat gtttcaaaat
      781 aagcattagg atgtactggc acttcttcat atacgatgga ttgccaatct ttacgtaaaa
      841 atgcgcgata gttgatcaag aattcttcta catcctttac taattcttct gcaaagtcgt
      901 caaatagttc tttttttatc tgtcgctttt ttgactgccc attgatgtgt tcacttattt
      961 tcttgatttc attttccaat gcttgataat ccgctatgta aatcggcatt tctacttggc
     1021 gaaattctgc gagccgctga gctaatttta tatccggtaa atatggctgt ttcatccgac
     1081 gattttggta caagacaaaa cagtattttt gccatagtcc ttcaggaaaa tcgatattct
     1141 tctgcttaag ccataataat tcgtctaagg ccagatcaac ttttgtcatt ccctgatgga
     1201 tcgaagctgc cactgtcgga gagacatgca ggtgatcggc aaagtggttg atgcctagtt
     1261 ttaggatctt tccggttttt ggcgatttaa cgatgtattg cacttttaat tctctaccac
     1321 actcacaata caatttttgc tggcttcgtt ttgttcgaaa aaacggattg atcttgaagt
     1381 cagaaaacac ccaatctgtt gcagctaaat aatgttcttc cataaaacga gagctgatta
     1441 gatatcggcg gtgcttatcg actagttccc gctgtttttt cgttaatttt gcatagatct
     1501 cccaacgttg actgcttgtg tattgtttag aaattttgat gggatagctt ttgctgattt
     1561 cttttggaaa ccattcttca aagacggatt gccattcttc cacggctgtt tctttccttt
     1621 ctaattacaa aaagctggct actaacataa cgttagcaac cagccagtgt ttcttgctaa
     1681 attagtgagt tgttccggca tttccggaaa tatcttcttt attttctact gctgcttcaa
     1741 ctgcataagt caaagaagaa gcaatgtctt ctaaagacat agaaggcgta cccactggac
     1801 gatcgatcac ttgatcgggt gagaatggca cgtggatgaa cccacctcga attgccggga
     1861 attgtgtttc gatcaaatga agcaaacgat acatgatatc attgcagaca aatgttcctg
     1921 ctgtataaga gatgtacgct ggtagaccat gatcttgtac attttttgtc attgctttga
     1981 ttggcaatga ggtaaagtaa gcggctggac cgttttcttc taaagccgta tcgaatggct
     2041 gatttccttc attatcaggg attcttgctt ctgctagatt gattgcgaca cgttcgaacg
     2101 agactgctga ccgcccacct gcttgtccga cacagatcac gacatctggt tggtgctgtt
     2161 ggatggcttc tttgactact tgactgcttt tttcgaatac ggtcggtact tccactttga
     2221 tgatttcagc accgctgatt tcatctggca ttttttttac tgcttcatag gctggattca
     2281 ctttgtcccc accaaatgga tcaaaacctg ttactagtac tttcatctgt tgttcctccg
     2341 tccgattgat ttaacatatg gttatctttt atcataccat tttccttgaa cagcgtaaat
     2401 aaaggaaaca atagtttaaa taacataaca gatcaaactt aatatattct tataaaaaaa
     2461 tagtgttcca ctacaatgtt agaagaggtt gcgacaatta ttctgtcaca acccctctct
     2521 tctattattt aaatagaatc atataagcaa tttggaaaac tagcataaat aacgcaataa
     2581 acaactggtt tttgatcact ccgtatttgt ctttcatctc cagcatcgct acaggcacga
     2641 tattgaagtt agcagccatc ggtgtcagca gggtcccaca aaaaccgcaa gtcaatgcaa
     2701 ccattcctat taacgctgga ttcgctccat gactaaatac gaatggtgca ccgatcccaa
     2761 ccgtcatcac ggtgatggcc gcaaatgcat tccccatgat taccgtaaat atcaccatgc
     2821 caagagcgta aatgatgatg ccgatgttca catttccttc tggaacgatc gtacctactg
     2881 cattggaaat cactgtccca actccagcgc ttgtaaatac cgcacctaga gaagctaaaa
     2941 gcattggcaa catgcttaac ggccctactg tgcccagcat atctgctgca tcatctaaaa
     3001 atgtacttgg tcgattatct cgagaaaaga acatcaagat tagcatggct gcaaaaacac
     3061 cgacgcccac gccgactaaa gcacctaaat tggtaaatag agcaaacaag atcgcaaaga
     3121 caccgatact caaagctgga ataaaaattt tcattcctag tttgtctgac attttttcca
     3181 tatattcttt tgatggaagc cggctttctc ctttgctgac tttcttagca attgctggta
     3241 tggtcatcgc aaagatcaag ccaccgttca cgattgccgg aagccatctt cctcctgcaa
     3301 taactacccc taagaccgtc cagaaaaagg ctgacccata acgatgagga ttggttttat
     3361 ctgttaaatt tcttactcca gtgtaaatca atacgagtcc catcacgata taaaggatct
     3421 ccagtaattt atcgcctaat aaaatatcag gatttgtaaa aaagtccatc ttattgcccc
     3481 tttcctggat aatatttctt cgctaatttc ttttctttaa gatagaagta gacacttgcc
     3541 acaactaaag ccgtgatagc cactggaact tccactaaag caagctgtcc caatgttacg
     3601 tcatatccta gatctttcag tgttgattgg actagcaacg cccctgctcc tccgatgaat
     3661 agtacttggc caaagaacca gcagacattt tccatagctg aagccatacc ttttagttct
     3721 tcttcatgct taggatggac ttctaaccct tttgattcga tggtccccaa tgccatcggt
     3781 aaaatgattg gacgaacaaa tccagcaact ccaccaaaac tcacgttaaa agccgcaaag
     3841 atcattcgaa agatcccata aatatctaca atcataccag cagatacttt cttgaatcgc
     3901 ttgatcaagg aagccgctga ttctttcaga ccatttcttt caagcgttcc tgttgccaac
     3961 ataatgatga taaaaatcgc catcccgcga ttgtttacaa aacttgtacc taaaagttct
     4021 aacattcctt gaatgccaag accgccagtc aaagctgtaa caactaaagc aaccattacg
     4081 atcaatatcg agtctaattt aaatgcaaac ccgagaataa caatcaagac gcctaaaagg
     4141 ctaagataat tttccatata ttttcctcca taaaatgaca atattttttt aattataaag
     4201 caaaacacat aaaaaatata gttgttttct cacgaaatag acactatttt taaatatttt
     4261 tcgttatttt tttatcacaa aaattatctt acttattgta aggtaaagct ttttttaatt
     4321 tattgcccga taatatatag aaataaggtc tagttactgt tttttttaaa tgattaataa
     4381 ataacaactt ctttctatga aattgcaaag cattcatctt cttttccgct aacgatatat
     4441 ccgtcagtgc ttggtacact ttactaaaaa gtatgagatt gccgatatct ggataggtgt
     4501 gctatactac agaaaaagat atacaatctg ccaccgggta ggataaagag gatgatcatt
     4561 ccattaggtc tttgaaggga tgattttcct ctttttgtgt atttttttat agttaaggag
     4621 gaatgtaagt atggcatgga tggaattaat catagcagga attttggaag tattctggtc
     4681 aacgatgatg aaatggagtg atggtttttc taaaatcaat tattcttttt acacagtgat
     4741 tggcatgatt gctagttttt actttttgtc aaaggcaatc aaaagtttgc cgatgagtct
     4801 ctcttatcct atctggacag ggattggcgc agttggttcg gtcataattg gtgtggtctt
     4861 gtttcatgat aagctgaatc tttccacttg gttctttgtg gggatgctac tcatcagtat
     4921 cattggcatc aagattacta gcggccacta gacacttgga ataagtactg atcagaaaaa
     4981 ataagccttt ttatttaata ttcaattttt ttatgaaaaa ataagaaata agtccaatga
     5041 cctagcgact tctccactca tcaggtgtat gcttgtacta tctatagaaa aggagtgaat
     5101 atttttgaaa agtctttcgg tccaagaatt atccaagaac tttggtcaca aacaagccct
     5161 cagcgatgtc agttttagct tatcccctgg caaaatcgtt ggattagtag gtcctaatgg
     5221 cgctggaaaa acaacgatca tgaaagctat tttaggactg atccattact cagatggaac
     5281 aatctgtatt ggtgaaaatg agatttctcc ctctagtcat aaagggttgg aacaagtagg
     5341 agcattgatc gaatacccgg gtatctatcc attcttaaca ggctatgatc atctgaagtt
     5401 attctctgaa accaacgatg tatctgctat cgacactatc gtgaatcagc tcaagatgga
     5461 aaagtacatt cacaaaaaag cgaaatccta ctcgttggga atgaaacaaa aattgggaat
     5521 tgctcttgcc ttactgaacc atccgtctat cgttatttta gatgagccga tgaacggttt
     5581 ggatccacaa gcaacaagag atgtgcgaaa aatcattacc gacttggcta ctcagggcac
     5641 ctctttcttg atctccagtc acttactcag cgagcttgaa aaaatggtcg atgagctgat
     5701 cctgatcaat caaggaaaga tcatcaaaca atgtacaatg gctgaattga accaaacagc
     5761 gcaagatttc atcgttatct ctacaacaaa tgatctagct gctcgaacga tcttgacaga
     5821 agctggatat actttggaag atcctgataa aatcaagctt ttaaaagaaa acgaagaatt
     5881 attaggaacc gtgatccagc tattgtctgc acaaaatatc catgtgacag acgtccagca
     5941 tctgacgaat gatttggaat cttctctatt ggaaattctg gattcagtaa agggggaaga
     6001 agaaaaatga cattgcttgt aaaacaagaa ttatttaaat tgatcaagaa aaagtcaact
     6061 gctgttttat ctgttctatt agttgttttg ctcataggaa cagcacttct agccaaaaaa
     6121 tacacgacga tcattgatcc agttgaaatg actgctcagc tttttagtgc cacatcttgg
     6181 attgtcttta tcatgattgc agctgcaagc acgatcattt cgatggaagc acaatatggt
     6241 acattgaaaa atctccttta tcgaaagtat tctcgaggag aaatattagt aagcaaatgg
     6301 atcacattag ttatttattc tgtttattta taccttttag ctattattgt cactgtgttg
     6361 atgaaactga ttcttttccc ttcgatttcc ttcacggaga aggtttctac tggtcaaaca
     6421 ctgatccaaa gcttgttcac ttatactttg ggtagttata tcggtttatg gctgatttta
     6481 agtttagtgt tgatgattgc ttgctttatc aatagttccg gcgcatccat ctcagcagga
     6541 atcgtctttt attttgcttc gtcaatcata tctggtatcc ttattgcact catccaaaaa
     6601 tgggagtgga tcaaatggaa tccgatcagt atgttgaatc tgcaaaacca aattggaaac
     6661 gaagagatca tgaagcaatt gactcatctt tctactaatc aaatgctatt cggtaattta
     6721 gcttacatcg ttttgttctt agcattagga tatctcgtat ttaagcgaaa aaatgtatga
     6781 tgactcatca aaaaagaggc tgtgaaagag acgttcagcc ttattgccga ttggctgtct
     6841 cttaaacacc gtttattctg aaaaaggagc tgtgacaaca tttgtgtcac agctcctttc
     6901 ctagtatgtt tttgaataaa cgacaggctc acaacctctc tttatacttc ttttatactt
     6961 ctatacgtga agcatcccag tggcaaataa aaccattgca atcactccga ccatcgtcac
     7021 acctataagt aaaatcttat ctaagtggat atgttgtaca ggctcgtttt gctccttacg
     7081 tgctttgagg taaaaataaa tgcctggcaa gaaaagaaca agaacaagca ttacttcatt
     7141 aaaggctacg actagcatag cccatacttg aaaggcactt gctaaaagcc ctactaaaaa
     7201 ttggacccat tctttccgct gataagaaag tttcatttgg tacaatccta agaaaagcca
     7261 cgtgaagaaa atagctgctg taccaagtgt gtaagcaaag ttataagcac tgtcagtgaa
     7321 taataatgaa agtaaaaaga cattcgtaca taacgtcgtc aatacgatag cataagttgg
     7381 tgccccattt ttgttgagtt ttccccatgc tttaggcaaa agtccgtctt cagccatgtt
     7441 tcccattgtt tcaatcggta agatcgtcca tgagagccaa acaccaacta aagaaatgat
     7501 caaaccgccg ttgatcacga ctgctcccca tttaccaacc atcatttcaa acacatagcc
     7561 catagcaggc tgcgccttga tcgtttgcag ctgattcatc gtcattgtcc catatggaag
     7621 catggaaacc aagacgtaaa taataatcaa gccgaatatc cctagaatcg ttgctttccc
     7681 aacatctgat tgtttttttg ctcgtgaacc tacgacagag gctccttcaa taccaacaaa
     7741 tacccaaagc atcaccatga tgcaactcaa tacttgactg gaaaacggga tcggctgtcc
     7801 attcgcattc aatataatgt cgctagaaaa gttatcaatg aattgttgga tcgaaaacgt
     7861 gctgatagct actacaataa ataaaaataa tggcactaat ttacagaatg tgacgatagc
     7921 attgacgaaa ctagcatttt cgactccccg attcactagc catgcatatc cccataaaaa
     7981 gactgtactc atcacgatcg atgccagatt ttgcccacct tcaaatactg ggaagaaata
     8041 tcctaatgcg ctcatcaaca atgttgcaaa agctacgttg cctaaccagc atgtgagcca
     8101 gtaaccccaa ccgctgataa aaccagcgaa acggccaaaa ccttcttctg cgtaactaaa
     8161 gatcccgcct tttaaatctg gacgtttttt attgatatta ttgatcgaca aggagagcat
     8221 caacattgct gttcctacga gtacccaact gaaaatagct gggccgccag ccgatccgga
     8281 gatgtccgtc ataataccaa atacgccacc tccaatcgct gaaccaatta ctaaggcagc
     8341 aagtggaatt aaaccaattc cttttttctg ttgctctgta tccatgtaag catcctccaa
     8401 aataaaaccg cttttatcaa aaagtataac aaaccttttt tatttttact taattaataa
     8461 aaactttaat agaaatataa ttctaccggc ttttttctca ttatacaagc aaagcgccta
     8521 gtccctttcc aaattacacc accaaaaaac ttaaaaaaga tgctatacta aaaggaaaga
     8581 attggaggat gatccatgaa cattttatat atatcgattt caggaaatac gcgtgccttt
     8641 gccaaacatc tagcagaata tgctgaaaaa atgcatgcag aagatcctgt caatcctgaa
     8701 gttactttaa aagaaatcca tgaaaatagt gattttacga aagaaacaga accatttttt
     8761 actttcgttc ctacttattt agacggcgga aatggtttag ataacggtga tacagaaatc
     8821 ttgaccgaaa cgatgcgtga atatctggaa catgaagaca atcataaact ttgtcttggt
     8881 gtagtcggta gcggaaataa aaacttcaat aatcagtatt gtctaacagc caaacaatat
     8941 gcacaaacat ttggctttcc tttcttggca gattatgaat tacggggaac accatctgat
     9001 gtgacacgaa tttatcagat tttagcagaa aacaataaat aataaaaaag aagaagctga
     9061 aaaatagatt tcagtttctt ctttcgtttc tattgtttct atcatattaa gctttgacat
     9121 ccatcacagg tgcttttgct tttgctttac ctgttttttc caagacaaag ttttttacac
     9181 gatccatatt ggttaccaag acgatcatgg atgtttcttt gcctgctgct ttgatcgctt
     9241 ctaagtcagc ttctgctaca agcgtatcag gtgtcacttg ctgcccttct gttactttca
     9301 catcaaatgg cgtaccgcct aagtcaactg tgttgattcc catatgaagc aagatttcta
     9361 aaccatttgg cgttgtgatc ccaatagcgt gtttcgttgg gaagacagag ctgactaccc
     9421 cagtaactgg agaatagata tgtccgtttt ctggttctac aaagtagcct tcacccatca
     9481 tcttttgtgc aaaaactgga tcacttgctt tatctaaaga aacaactgtt ccgtcagcaa
     9541 ctgatgagag gatagtcaca ctttcagctg aagtttgagg tactactttt tcaggcactt
     9601 catttactgt ggctgtttca gtcgctaatt cttctttttc taaacggtct ttaggaatac
     9661 cgaagaagaa tgtagcaacg aagccaccag cataagctgc caataatcca aggatgtagc
     9721 ctaaccattt accgtcagag atcaatggga tcaaagcggc tcctgaaggt ccaatagcga
     9781 tagccccgac atttccgatc attccgatca ctgccccgcc gatacctcca ccgatacaag
     9841 cagtaataaa tgggcgtcct agaggtaatg ttactccgta aatcaatggt tcgccgattc
     9901 ctaggatccc gactggtaaa gctcctttga tcatttctgt taattcttta tcttttttgc
     9961 agcgaatcca taatgccaat gctgcaccca cttgtcctgc accagccatc gcaagaattg
    10021 gaagcaatag cgtacgacca gtttcatcaa tcatttgcac atggattgga gtcaaaattt
    10081 gatgcagtcc gaacataacc atcggcaaga ataatgtgcc tagaacgaag ccggcaaatg
    10141 ctccaccaac gccaagtacc cagttgatcc caccgaccat gccatcagaa atgaaacctg
    10201 ctaaaggcat gatgaagaaa atttcaatca gaccgatggc aatcaatgaa agagttggtg
    10261 taacgatgat atctaccgca tcaggtacta ctttatgcag ttttttctca acgattgaca
    10321 atagccaaac agcgaagatg acacctagga tcccaccttg tccagctgca agagcttcac
    10381 cagtaaataa gtttttcagt ggtgcttccg gattcatccc tgtcagcatc acaacggccc
    10441 cgataactcc accaagagtt ggtgttgcac caaaaacttg tgcagcattg atacctgtat
    10501 agataactag gtagctaaac atcccgtttt tcaagatgtt catcacatcg atatattgtt
    10561 gccatgttgc tgcatcaagt gttccggctg tgactaagtt tgctaaaact gcggcaatcc
    10621 ctgccacgat cccagtaccg acaaatgcag gaatcattgg cacaaagata ttagaaatgt
    10681 cttttaatac cgatttgatt ttagatggtt tttgtttcga tttttgtgcc gctttcattt
    10741 cttgtgcccg ttcgtttaca cggtcttttc cagatgctga tgaatttgct gtagctgtac
    10801 ttacagaaga aagtttttct cctaatttca cgcctgccaa atcaaccatt tgctgtgcta
    10861 ctttgttcac tttcccaggt ccgatgatga cttgaagctg ttcatcttct actacaccaa
    10921 gcactcctgg aatcgctttt aattcagaga catttacaag atcatcattg atgatcttca
    10981 tacgcacacg agtcatgcag tggacaatgc tttctacatt gcccatgccg cctgcccctt
    11041 tataaatttg ttttgccagt tcttccaaag tcagttcgtt ttttgccatg gtcttttccc
    11101 cctcataagg tcccttttac aaatccgttt gcttcagcta attttgcttg agcttcctct
    11161 ttatcactat ttgtcaaaat catgacgata gccagcttaa cattttgatc tgcttcttca
    11221 aagtactttt cagctgtttc gtaatcagct tctgtcgctt gcatgatgat tcgttttgag
    11281 cgttcgatta gtttttcatt tgttggtttg acatcgacca tcaagttatt gaatacttta
    11341 cctataccaa tcatactgat agtagaaatc atattcaaga taagtttttg tgctgttcct
    11401 gacttcaatc gagtagagcc tgtcaaaaat tctggacctg catcgacttc gattgggaaa
    11461 tccgcgtgtt tactgatttc ggcttgttta ttgcaagaaa tcgttcctgt gacagcaccg
    11521 atcgattttg cgtaatctaa tccaccgatc acatatggtg tacgaccgct agctgcgata
    11581 ccaataacta tatcattttt tgtcaaattc agcttgatta gatcttcttg ccctagctca
    11641 taagaatctt cggccccttc gacagctaca gtcattgctt cttctccacc agcaattaga
    11701 cctatgacca tttccggttc tacaccgaat gtcggtacgc attcagcagc atctaacaca
    11761 cctagtcttc cacttgttcc ggctcccata taaatcagac gtccaccttt tttaaaggac
    11821 tcaatcgtgt tagcaatcac tggttcgata cttgtcagtt ctttttcaac cgcagcggcc
    11881 actttctgat cttctttgtt cattagttga acggcttgag aaatactcat ctcatctaat
    11941 ccaaaagttt cttggtttct gcgttccgtt gttaggttct ctaaattgat tttgctcatt
    12001 tttatcttcc ttcttttctt ataaattgat agttcatacc agctttgatt tggttgatca
    12061 atggtagctc ttctttgata actttagcta ctacattcac tttttcatcc gctggcaaat
    12121 catatttggt taattggatc tcacccatat agcgcaaata cttttcgtta tctaaagtaa
    12181 tagacccttt catacgcgta gctgtatttc ttgctgggat aggcggaatc tctcgaaaac
    12241 gtgcatctac gcttcgtatg acatctcttg catcgtcttg ccgattcgta tgcttcccta
    12301 atatatattc gtaaaattct tcatctacag gttccgtatg gagcaagact gtctgttctt
    12361 tttggaaaga agcaaattgc tcctgaacgt tttctgacag acctgcatct ccgatgtaaa
    12421 caatatccgt gttacttgct aatagatcta gagcgcctgc aagaggatgg atccctcgat
    12481 gttcttccaa agttggcaat ccttgatata gtgggcctct caactctgta tctcctggta
    12541 caaaaccttg gacaaggaga ccttgaattt tgagccattg attttttttc tgataccatt
    12601 ctttgtccag ccctgtttcg ggacgtggat aataattatg ccaagcttca atctgtgaga
    12661 aatcagcttc tgcttctttc aattcatcga tatctttagg cgtgatcgtg ctagcattca
    12721 aactgatttt caattgatgt gaccagtcgg caatctgctg attggaaata tgataatcca
    12781 ttcttaaacc tgttacacca attgctttca aaggcgttag atcttctaat gaaaaacccg
    12841 ctcgttccaa tgcctctcct gaaatatcga ccatcaattc tagtttattc tttttcgctt
    12901 cgcttcctag ttcgatcaat cgcttttgat atgccgaaac atcatcttct ggtatatgca
    12961 tggaagtgaa aataccgaca aagccattgg atgccatttg gcggatatac tgtttcttct
    13021 cttctgacaa agaatcgttc ataaatattg aaaagccaaa catattatcc ctctttttct
    13081 gtatccgtct tcatttctat gactagagta tatatctaaa gaaacaaaat ttcaatactt
    13141 ttattaaaat aattaaattt catttctaaa ggttgagttt atattatcaa aagaattgtc
    13201 ataacctaaa aaaggcactg ctaagcaaaa gcagtgcctt gaaatatttt atttaaataa
    13261 cacaaaaaca taattactca taagaaacca attctgtatt atctaccatg aatgtaaaga
    13321 acccctcatt aggcatcgga tgaaaataag cattgatcac tcttatcaag gcattatggc
    13381 aaactaacag atagacattt tcttcgtctt cgatgcattc tttcaataaa ggaacgatcc
    13441 gtgcatacac atctaagact gactccccat ttgggaatcg tacagcgaac gctaaacgtg
    13501 ctttttgaaa gttctcatct ttgcttggca gtccatcata atccccaaaa tccatttcta
    13561 ccaatcgttc atcaacggtc agcggcaagc tgagacgatc agcaactgct tgtgctgtat
    13621 ctcttgctcg ttgaagaggg gaatggatga ttttcgtgat tggaacaggc aaatctacta
    13681 ccttttctgc tagtttctgt gcctgcatct gtcctttttc agtcagcggc acatctgccc
    13741 gtccgcaaac taatccttgt gcgttccaag ttgtttctcc gtgtctcgtt acataaagca
    13801 tgtgattctc tccttcgttg gcaaagttcc ccttaaccat accttgttgt tcttgagatt
    13861 acaagggtta gattctctca agagaaataa tctcagtaga tactttatcc aggaaggttt
    13921 gatcatgttc cactagtaac atggcaggtt tcacgttcaa gatcagttgt tctaattgtt
    13981 cttgattgaa gacatccaaa taattcaatg gttcatccca tgtatatagt tcagctggct
    14041 gtgataaaga tttagccaat tccacttttt tccgttggcc catactcatc tgctcgatct
    14101 tgttatgaaa aacatctctt tccatcccaa gctttcggag gttgttcaaa aatgcttggt
    14161 agtctacttg gtttttctct gcaaattccg ccaacgttcc tcgattgtct tcataatttt
    14221 ggcttgcata actaatgctc agatgttttg gctggtattt ttctcctata accttgccgt
    14281 tgaatgcccc cagaagataa tggataatgg atgactttcc tgcaccgtta ggacctgaaa
    14341 tcgccacccg ctgatgaggc tcgattgtaa aatgaattgg ctcgaataac agattttcat
    14401 accctaattg aagatcttct acgcttaaaa gtcgcttatg gtgagacgct tggctattca
    14461 tcgtcaaaga atcgatatat tcgatatctt ttaatagttt ttctttctcg ctgatctggg
    14521 tctccatccg attcacgatt gctttggatc gtttcatcgt ccgtgcagca tcagcaccca
    14581 ctgctccttt attcactcgt ctagattcag tatcgatgaa tccgacttgt ttctttgttt
    14641 tatctccttc tcgggaacga gaccattcgg ctttttcagc tgctgttttc tttagcctac
    14701 tgacttcttt tttcaatttt tcattttgag ccatttcaaa ttcatcacga agttttttct
    14761 gttcttcata gatagagaaa ttcccttgat aaagttccag ttgacttttt tcgattgcta
    14821 aaacatggtc cactacttca tcgataaatc cccggtcatg gctgaccacg atgaagcctt
    14881 gttttttctt tttcaaataa gccgctactt gttttctacc agagatatcc aaatgattcg
    14941 ttggttcatc gattaacggg aaatgagtgt catccacaaa taaaagtgcc agtaggactt
    15001 ttgtcttctc tccccccgat agtgtgctga attctctcca taagatttca ggatctgttt
    15061 gcatcaattg gagctctctt tcgatttccc atatctcaaa atccgtaata tcatttaaca
    15121 cgtaataggt taaacgttct ttatcttttg tctgttgcgg gaaataggca aattcttgct
    15181 gatggattac ttgcccttga taaggtagtt tgttttgtag aatattcagt aaagttgtct
    15241 ttcctcgacc gtttcgtccg ataagtccta gtttccattg tgtgtcaaaa tttagatttg
    15301 cttgttcaaa taataatgtg ccttggctgt cgtagccgaa tgtcagattt tttatttcga
    15361 ttttagacat tttccatcac ctcgtaaaaa aagaccagtc ctattttcag aactggctaa
    15421 agaggatgca agggttggat acacacaaaa agacccatac atcgaaaaaa ccaagccaat
    15481 cccgaaaatc tgcacactgc ttccttgtct ccacaaggta cagtctgaat gcagctttca
    15541 tcaatcgact taatttttca atgcacggat ccctcacttt gtcctatatt tgaaattacg
    15601 atagcataaa gaaaatgatt ttgtcaacta cttcgggagg atggtgaaaa atctgctaag
    15661 tgtctgtcct aagatttttg ttttttctaa tgtttgcctg tgttccattg cttcttctaa
    15721 acctattgga cccaaatgaa tacttaagac aattgggaga aaatcagaaa gtccttctag
    15781 ctcttggtct ctacttccgc aaatagcgat tattggtttt cgatattttt ttgcaagcac
    15841 tgctacaccg tatggaactt ttccgtggat cgtttgctga tcgatccgcc cttctcctgt
    15901 aatgatgaca tctgcttgtt cgatcttttt ttccaatcca gtgatttggc tgactaaatc
    15961 gaaaccagaa accatcttcg ctcccaacaa aaaaagggct ccaccaatac cgcctgctgc
    16021 tccacttcct ggaatatcat ctaaatccac ctcccagaaa tcttttattt gctgagcaat
    16081 ctttcctgct tgtttatcta agaaagctag cgtcgtatct attcctcctt tttgtcttcc
    16141 aaattgccaa gcagctcctt gttgacctgt atatggattg gtaacatctg cagcgataat
    16201 caattttact ttagaaacaa gaacgtttct tcgatcaaaa tgaagttttt tagtagataa
    16261 taaaggattt ccttctgtgt acccttctaa agaagcaccc aaggattgga gtaatcctag
    16321 accaccatcg ctacacccgc ttcctcctaa agtgacaata atttgttcta cttcttgaag
    16381 cagtgcatct ttaataagtt ctcctaaggc ataactggaa gcaagtcgga tagtttgatc
    16441 cgttggttta tcaagtagat ctaaccccaa tgcttgtgca gattcgatga ctgcggtgtt
    16501 ttttccttgc caagttgtca ataaatagct gatttttcgc tgacggaata agagatccat
    16561 cccatcaatg gtacgccatg ttcccctgag cgcgtaatag attgcttctg cagtattttc
    16621 tccgccatct gcaatcggca cattgatttt tcttccttta cgatcttccc agccatttag
    16681 aactgcctga tttagttcaa atgaagaagc acttccttta aatgaatcaa ttgccgccaa
    16741 aatatccatc tgtatccctc actttcttct taagtaagac actttttttc atttttttca
    16801 aacaaaacaa tgctattttc ttccattttt ctatatacta aaagggaact cattgaataa
    16861 aggagagaaa aaacatgaaa atcgcaatag ctggggccgg agcaatgggc agccgaatcg
    16921 gattgatgct acatcaaagc ggaaatgagg tcctcttgat cgatcgttgg cctgctcaca
    16981 ttgaagccat tcgtacaaat gggttgattg ctgactttaa cggtaaagaa gtggtcgcaa
    17041 aactgccaat ctattcacca gaagaaatca tcgaaagcaa cgaacacgtg gacttgatcg
    17101 tagcattaac aaaagccaat caattagatg atatgttttg ttcgatccaa tccattatta
    17161 ctgacaatac ttatgttttg tgtttactaa atggattagg tcatgaagat gtactggaaa
    17221 aatatgtgcc aaagaaaaat atcttatttg ggatcacgat gtggacagct ggtctagctg
    17281 gtcccggaaa agtcacattg ttaggtgatg gagaaatcga actagagaac ttggaaccag
    17341 aaggcgaagc atttacaaaa aaagttgtag aagtctttca agaagcaaat ttaaatccga
    17401 tctatagcca taacgttcgt tattccattt ggcgaaaagc ttgtgtaaat ggaacattga
    17461 atggtttatg cacgattttg gattgtaata ttgctgaact aggcgcgcaa aaagcggcag
    17521 agagcatggt tcgaacaatc gtatctgaat ttgcttctat cgcagcaaaa gaaggaatca
    17581 tactagatca agaagaagtg taccaacata ttgcttctac ttatgatcct gacaacatcg
    17641 ggttgcatta cccatctatg taccaagacc tgatcaaaaa ccatcgtttg actgaaatcg
    17701 actacatcaa tggtgccatt tggcgaaaag gacaaaaata tgatattgct acaccatatt
    17761 gtgccttttt gacccaatta gtccatgcaa aagaaggaat ccttggcgca gaataaaagg
    17821 ctctctgatg agaatcagct gaatcagcag ctggttctct ttttttaagc ccaataaaag
    17881 atcaaaaaga aaacacaact ctcatgatgc cataagaatt gtgcttgttt gtttcagtac
    17941 ataatctctt caaaatgtag gttttttatt tgttttcaac agaggagagg tcatattcgt
    18001 attgctcata aatagtggaa tcgttagtga taaatcgttt tgcccaattt tctgcatcat
    18061 aaaattccaa tagctctgat aggattggct taaatggtgt atgcagaaat tccggtaatt
    18121 catctaaatc acgttctcga agcaaaaaaa tattttcagg acgataaaaa tgataatgag
    18181 caatcgcttg attatccgtc actagtttct tttgaaaata catggattca aatgtccgca
    18241 aagtcactcc ttgctgaccc tcccgcaaca gttccagaat cccgcgcgat tcccctgttt
    18301 ttttcaggta ctcttcataa gtaagatatc caggttgttc attccctcga tgtggaagaa
    18361 tgaaatagtt ggtcgtaaca tctcttttta taaattcctg cttatagctt tctgctcgtt
    18421 cttttctccc attattcgtt gcaccaaaaa atagatccgt ctttggttcg ctagaagaaa
    18481 aattcatatg tttcgaataa aatgaactat tatgtttcag cccaagttct tttgcttcca
    18541 aaaaatcaaa atgataaatc tcatcgattg ccggttcatc ttgtgcctgc ttcagcatcg
    18601 cctcgtgttc tgctttgaag tgattccaaa aaaataacac aatttttgca ttggtaaatg
    18661 ggcgcacgcg tcgagccatc tccatatcaa atccataatc taaaaaaacg atcagctgat
    18721 aatttgccaa ctgttgtcta gctgatttaa tgaattccga ctgtagtaaa tcttttccgg
    18781 accaaacatc taaagagcgg atggaaggca aaaaataaag tgatttattt tttgcaacta
    18841 gcagtacgtc atttttgttc atcttttccg cctcactttc tctgtcactt tttcctatga
    18901 tagcctgttt aaatagtaaa aagccagtaa aacgtttcct atatttgtat gaaaatttaa
    18961 catttgtatg aaaatatgat gaaataaatc attcttctat taaaattcgc ctaaaagttt
    19021 tctgaatagt tgtaattgtc tgaaaatttt ttatcattag tcattgttaa atattgctat
    19081 ttattcttaa tataaatttt gattgtgaat ttaaaagaaa gaggtcattt atggaagata
    19141 aaaaattgaa aaaacaactt agctccagac atatcaccat gttagcttta ggtggagcaa
    19201 tcggtgcagg tctatttaaa ggaagtggcg aagcgattgg gatcgccggc ccttctgtat
    19261 tgattgcttt tttgattggt gggctgattt tatatatcgt gatgaaaggt ctgggaaaaa
    19321 tcgttttaag cggtggcgac acgcatcacg gattatctgg tttgatacgc ccttatctag
    19381 gtgctcattc tgctgatttt actgattggg tctactggtc tatgtggatt atcaatatca
    19441 tcgctgaagc tgttgcagct gcttcctttt tgcagttgtg gttcccgcac attccagcct
    19501 gggtatttgt ttttatgttg gctgttttaa ctacgatcat caatctttat tcggtacggt
    19561 tattcgcaga aacagaatat tggctggctt ttgctaaaat cagtgtcatt atcttactga
    19621 tcatttttgc tacttatctt gtcggtcagc aaatgttggg cacaggcgtt ttccctaccc
    19681 ttcagcaatt gactgaccat ggtgggttta ctcctcatgg tatgaaggga atcatcagtt
    19741 ctttgcttgt agttatctat tcttacggcg gttctgaact gattgctatc acggtaagcg
    19801 aagcagatga tcctaaacgt gcgattccta aagcaatcaa aggtgtcatg ggaagaatca
    19861 tttcctttta catcattcct ttgtttttgc ttttgattct ttttccttgg aatactttag
    19921 caggcacgaa tgtcagtcct tttgtgatgg tatttgaaaa aatgaatatc ccatttgcag
    19981 cggatatcgt caattttgtg attgtccttg ctttgttctc atctatcaat tcgggtgtgt
    20041 atgcatcttc aagaattttg ttcttccgtt tgaaggatcg aaaaggttcc tctagaaaac
    20101 tagctgtttt aaacaagcat caagtaccgc aacgtgctgt tttattttgt accagtgttc
    20161 tttatcttgg tgtagctctt tcttattttg tcggtgacaa attatttggc tatctggcag
    20221 gttccctttc gtatacagta ttattgatct ggatcattat cagtgcggca tcctttgtac
    20281 tggcactaag aaaaggaaca ttatgggata aaggaatcag cttttttgca ttagctgtct
    20341 taggattgat tttccttggt atcctgttca cgaactccat tggggtaact gtattgactg
    20401 gcctgcttta cctgttcatt tatttcagtt atcaaaaaaa gaatgatgcg ttcgtattga
    20461 cgaatgaatg aaatcgatag aaaattttat tttatttatg tggaatagat ggagctattg
    20521 aagaaaggag ttgtgacaaa agtcttgttg caactccttt ttccgaataa acagtctcat
    20581 gacctcttgg taaacggtgt tcaaaaaccc tctgtgcaaa ataattgatt gttctccatg
    20641 ctcatgacat gatagaagaa aggaatgaaa aaaaggagtt tgttttaaat gaaaaagtat
    20701 tggaagtttt tgttgatgat cggtgtttca acggtagtta tgtttggtat gatgtacttg
    20761 aatgtctatg cgctcgatca tatcttcttc agtcgtacac gagtattcat ggcgttgatg
    20821 atgggtgcag tcatggcagt catcatgctg ttgttcatgt ggaaaatgta tgaaaacaaa
    20881 aagataaatg ttatgatctt agccgctagt cttcttgttt ttgccggttc cttgtttatg
    20941 gtacgaagcc aaactactgt caacgacaca gcttggatga aggccatgat tcctcatcat
    21001 tctatcgcta tcctggcaag taaacgagct gatttaaaag atcctgaagt aaaaaaatta
    21061 gcggaagaaa tcattcaggc acaagaagaa gagatcgaca aaatgaaaaa aatgatcaaa
    21121 gaaatggaat gaccattatc cgtccaaata aaaaaagagg atgttccaga agttatcagc
    21181 ttcaagaaat aagaagaagc tacttctgga acgccgtgaa taaggggttg tgaaaaagct
    21241 gccctgcatc aagtaataag aacagccaaa caaaaatagc ttctcctatt tttcgtttgg
    21301 ttaggcttat taccgcagat gcaagctttt gaacaccgtt tattaagagg ttgtaaaatc
    21361 agcgttctga cctgagtatt agagagacaa atggaaaaat agttcctcat attttgccat
    21421 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttatcgagag gttgtgaaaa
    21481 agtcgcttag tttcgcgtat taagaaaaat tttgtgaaat ggctttccac atttttgtat
    21541 aaatttggct taataccgag aaactggctt ttgaataccg tttattcgta aaagggattg
    21601 tgacaaaagt cttgtcacaa tcccttttta tgtttttatt gttctaattg cgctgtcttg
    21661 cttactgctt cttgcggttt cacaaatttt tttgagattc cccaacctgt gaaggcactg
    21721 accatcgaaa acacaggaga aagcaaactg aaaaatacga atggcaagta agtgagtgta
    21781 ggaataccaa atgtacttgc tacgaaactt ccggcaattc cccaaggcac taagtagttg
    21841 attactgttc caccatcttc tagcgttcta cctaatacag ttggatcaaa tcctgctttt
    21901 tcataagttt ctttaaatgc attaccaggc agaataacag ataggaattg ttcaccaata
    21961 aaaatattta ctccgatact tgtcatcaat gttgtaaaaa tcaaatttgg tgtgttcgtc
    22021 atctttcttg atactcgttc catcacggtt gagatcaagc caaattcgat caacaatcca
    22081 cctaatgaca aagttagaat aatcaatgac acagtaggca tcatactttc gattcctccg
    22141 cggctaagca gtgaatcgat ttgttggttt ccagtatttg aaacaaaccc tgattcgatg
    22201 accccagcca acttcgttaa ggaagtttgt gggttttgaa taaaaatcat tcctactgct
    22261 acagcgatat tcaacaaaat cgttaaaatt gccggcacct ttttccatgc acacagtaac
    22321 attaaaaata aaggaatcag tgaccagatt gaaatagtaa agtttgcttc tagaacatca
    22381 gtcacttcac gaatagatga aagacttgcg gctttacttg tgtgtcctaa aatcatgaat
    22441 aaaaagaaag aaacaacaaa tgccgggaca gttgaccaca tcatatgctt gatgtgtttg
    22501 aacaaatcgg catcaacaat agctgctgct agatttgttg attcggataa tggagacatc
    22561 ttatctccaa aaacggcacc tgaaacaata gctccaacaa ccagcgctgg atttaagcct
    22621 agtgttgtcc caataccgaa aaatgcaatc ccaatcgttg acataacagt aaaggcactc
    22681 cctacagcgc tacctacgat tgcacacaca acaaatacag aagggacaaa ccactggaca
    22741 ctgatcaatt tgaacccaat gaccattaga gttggaatga tccctgcttg tatccataca
    22801 gcaatcaatg aaccgactaa aataaaaata aagattggga tgattcctgg tttgatgcca
    22861 ttgatgattc cttcgtgcag ccaatctgtc gggtatcttt ttatcactgc atacaacatg
    22921 accattccga tcgctgctaa gatcgtgata ttaggtgaga cctttaatcc gacaacgcca
    22981 atcgcaatgc ctaaaacaat aaccattaat acaagtgttg cttctaaaaa acttggtgtt
    23041 cctttttttc ccatgataat ctctcctttt ttagttgttc ttatgttcta aaaaagttaa
    23101 gatatcggat tactccgccg caattcatcc gcgattcctc ctttataaaa ataaaaagac
    23161 ctgttttaaa ctaaggacga atgactccgc ggtaccacct taattaaaaa cagatctgtt
    23221 tttcactttc aaacttttat tcaaatgtat ggactttcca tgtaattcgt caattaggct
    23281 tgatcggttc acagcgacca ccgactttct gaacaaaaca cctaaccgct actgcgtgaa
    23341 aagttgactt gtacgaagtt taccttccat aagatcattt gtcaatgaaa aagaaaatat
    23401 tttttcattt ttctgaaaat tatttttata actttcacac acaagattat tttttactag
    23461 aaagtagcgc cctcttgttt ttttcttgct actatttctt gatgttcttg cttgattctt
    23521 tctaatagct ttggctcttt caacagatca agagctgtat tggcgagtag ttctgctgca
    23581 atcgcaatag aagcaaggcc tttgtcactt ttagcagcag ctttgaattc ttctgtgtgt
    23641 ccggcaatat atgtctcaga gattgctacc gtaggctgga ttgttggtat gacttggctg
    23701 acatttccta catcagaaga accgagactt gttctttgtt ccgtttctat ttcttcatct
    23761 ggaacacctg cttcttttgc atgctggaag aataagtcat caaaagaagg agtaacgatg
    23821 acatcatcaa ctgcattttg gaacaatcca aactcaaaag tcgtgcccgt acttatcgca
    23881 gcacctcgta cgatattttc cactttttca tatactttat ctaatgtttg ccgatttcct
    23941 gcacgtaaat agaaacgtcc agcagcgtaa tctggaatga cgttggcagc tactcctccg
    24001 tctgtaatga tcccatggat attgacatct tttggcaatt gcaagcgtag agcgttgatt
    24061 ccattaaaca cttggatcaa tgcttccaaa gcatttactc ctttttcagg tgctgctgct
    24121 gcatgggaag cgacaccgta aaatttgatg tcgactggat cattcgctaa agattctgtc
    24181 gttttcccat aacgaaaagc tggatggacg cataacgcta catcgacatc ctcaaaaaaa
    24241 ccttctcgaa caaagctgcc tttagctgat ccgttctcgc ccccttcttc ccctggggtg
    24301 ccatatacac ggatttctcc accagtttca tcaatgaatt gcttcactat gctggcggct
    24361 aatacggagt aagtaccaaa caaattatgc ccgcatgcat gaccaatacc tggtaaagca
    24421 tcgaattctg ccaaaaaggc aattgtggga ccgggtttat tggaaatata acgtgcatca
    24481 aaggctgttc ggtgtccagc tacttctttt tctacccaaa acctttcttt ttctaattgt
    24541 ttaatcaacg ctgctgagga ataaaactca tagttactta cttcaggatg ttcgtggata
    24601 tctagagcaa gtgcttgata ttctggtaaa cgatattgga ttagatcctt caattggttt
    24661 gttgagattg ttgttgtcat aaaaaattcc tcctatgcta gtcatttttc ttattttctc
    24721 ccgaatgttt cccatgcagg cacgcttgat ccttttgatg ttttctcgat tactttgact
    24781 gtgtcttctg tttgataagc gtctactatt ttttgatacg ttttattgtt ttcatcttct
    24841 tttcttgcaa cgatgatatt cacataagga cgtgcatggt catccactgg ttctaagaag
    24901 atggcatcag aagcaggatt aaatccagca tctacagcta caccgctatt gatcactgaa
    24961 atgtctacat ctgacaaagc acgtgctgtt tgggaagcat ctaattcaga aatgtctaga
    25021 ttttttctat tctcggtaat atcagaaaca gtgggcgctt gtccttttgc cttatccact
    25081 ttgatcaatc cagcagtttg caataacaga agagctctgc cgccatttgt aacatcatta
    25141 gggattgcta cttttgctcc gtctttgata tcagctacat ccttcaaagt gttagaataa
    25201 attcccagcg gtgcattgac agtatttccg atcgatacta aatcagttcc gtgttcttta
    25261 ttgtaattgt ctaaaaagaa ttgatgttgg aaagaattca aatcaatcga tccatctgct
    25321 aaagccacat ttggttgatt gtaatctgta aatttcacgt attccaaatt aatgttctcc
    25381 tttttcaaac ggtctttcac gttgtcccat acatctgtat cttctccaat aatccctagt
    25441 tttacgatag tttctttttt gtcagttgta tctgcttttc cttggctaca ccctgccaac
    25501 caaataattg ctacaaatgt aatgactaca aaacgaataa tttttttcat tttttctcct
    25561 ccactttcaa tgtgtaattt ttttaatcag ttgattactg ataaattgac ttaaaaaaac
    25621 taagattaga atcaataatg tagccacaat cgttacatct gtttggaatc gattataccc
    25681 tctcgatata gcaagattcc ctaatccgcc tgcacctact gctccagcca tggtagtcag
    25741 tccgatcacg ttgatgatag tcaacgccga gacccgaatg ataccaggca aaccttctaa
    25801 caaatacaca cgtaaaatga taccgattgg actggttccc atcgcttctg ccgcttcgat
    25861 caccccagga tcaacttcta gcagtgcgtt ctcgatttga cgagcaaaaa acggaacaac
    25921 tccaaaaatc aatggcacta aagctgcttt cgcaccaatc gtcgttccaa ctaagaaacg
    25981 agtagtcaat gctaaaagag aaagcaagat aatgaaaggg atggaacgaa tgatattgat
    26041 cagcttatca agtatttcaa atagcagacg gttagctagt aatccattag ggcgtgtcac
    26101 tactaacgtc acacctaaga tgattccaat catcccgcca atgaatgctg tccaaaaaga
    26161 catatatagt gtttgcttcg tcgcttcgac aaattcatcc ggaatcaaat aaacattggg
    26221 caaatatgtt ttaaagaaat cagtcatttt atcttcctcc ttcgatcact ttgatacgac
    26281 tatctaaatc gtttttttgt aaaatattta tttttacacc agatttgatc aaataatcca
    26341 atgctttttt ccgctgtttg gtttctccag ctaaagtaac gatcaaactc cctaacggcg
    26401 tttcttgtaa taactctaca ttgccatata aaatattcgc tgttacttga tatttgctgt
    26461 acagatgagc gattagaggt tcgttcgtct gatttccaat ataacttaat tccaccagcc
    26521 atttattggc gatctgatcg gcaaaagcag aatgggcaat gatcgtttct aatgcttggt
    26581 caagatgagt agctgttcga ataaaatctt tggtcaattc ttcttcagga ttgctgaaga
    26641 tctggatgct gctacctttt tcaacgattc ttccatcttc cataaccgct accttgttgc
    26701 agatttcttt gacaacttgc atctcatgag tgatcaggac gattgttaaa cctaactggc
    26761 gattcaattt ttttaacaat gcaaggatct gaagggtcgt tttcggatca agtgcactgg
    26821 ttgcttcatc acataataat accttaggtt cattcgccaa agctcgtgcg attgctactc
    26881 gttgtttttg tccccccgac agttgtttag gataagcaga tgctttttct tccaaaccga
    26941 caagttccag tagttcattc actttttgac gacgttcctg tttcgatttt ccagaatact
    27001 ttaaagaaaa atcaacgttg tcaaaaatag ttcggctttc cattagattg aaatgctgaa
    27061 agatcatacc gatggccttt ctttcttttc gcaattcttt gggagagagc tgactcagat
    27121 tcgtctgatt gacaatgact tctcctgctg ttggtttctg cagcaaattc atcacacgaa
    27181 ctaacgtact tttccctgca cctgagtaac cgacgattcc ataaacatcg cctttttcaa
    27241 tcgttaaatc tacagaatct actgcctgta tctctttttc tttttgtttg aaacatacag
    27301 aaacatctcg caattcaatc attaaaattc ctccttatct aaaaaaagcg tcctcaagaa
    27361 aatgaaaatg tcattttctt gaggacgctt ttttgcgtgt taccacctca tgttcaagct
    27421 gtgttcacac acaactcctc ttcaagtacg atcatactct agcaagatat cggtcgcagc
    27481 cgtcatcgcc ttacatctat gctcgggatg aattgctcga tggccatttt ccaatagtcg
    27541 ttccttgctt cttctcagct accgaagctc tctgtcaaag gttcttctat cgtacttacc
    27601 atttcaatgc aaataatatt caaaaaaaaa gtccttttac taacataaac tatgtcagta
    27661 aaaggacgac gtatcgcggt accacctttt ttcggaagtt tccttccctc aagcccaaca
    27721 tctcaaaaag agagattggc gttcgtttta acggtcgaac agttccgaat ttgcctactt
    27781 atcgacaaat tattctccaa ggccattttc agcttttctt acttgactct tctcaccagc
    27841 cagagcctct ctgcaaagtt tccaaactta ctttcctttt caacgaaatc gatattttgt
    27901 tgttgggatt aatctacatg aggaaaactg aaaagtcaag tacgaaattc aaattatttt
    27961 ttctatattt atttttctgt ttttttattt aacatttcaa taacagttcg aagatctttt
    28021 ccttccgcaa gaagtttcaa tttttccttt tcttcgacgg tataatttcg gacaaaactg
    28081 gaatcaggta tcaaaacaac gcctaatcct gctcgtgaag cagctgttgc tcctactaaa
    28141 gaatcttcca ctgcaaaggc tgaactagct tctaatcctg ttcgttccaa agctgtcaga
    28201 taaggaatcg gtgaaggctt gttctccgac acttcgtctc cgaatgtaaa cgtgtccaag
    28261 taatcagcta atttaaagtg atccaagata tctgttgctc ttttcgtaac agtggtcgta
    28321 gcaatgccta gtttcatatg acgttctttt aagtctgcca atatttcttt tgcatatggt
    28381 tttaagtgga tggctccgct tgtcagctgt tgataaaaat attcttcacg cttcgctcgg
    28441 acttcctgta ctttttcagg gctacctgct gctttcacta aaatatcaaa actttgtttc
    28501 cagttttttc cgccccaagc gtcaacgatt tcttttggga tatggatatc aaattgctga
    28561 aatccccaaa gccagccatc acgatacgtt ttttctgtgt caactaacaa accatctaaa
    28621 tcaaatattg cacctttcat ctatacatta atcctttcca aaacaataca catagtttag
    28681 cacgactggt ccaaaaagaa cagaagcaaa gaaccagcct tctcgtttat aagagttctt
    28741 ggaatcgacg gatatagatt ttcttcacag ctgtcacaag cgccagataa gcgatgactg
    28801 tagcaaataa ccataaccag taattgccag gaagtggcat caagcctaat tcagcaccaa
    28861 aacttgtaaa aggaaggaca gaaccgacaa taattcctaa tgtagtgata acaaacatgg
    28921 caaatgttgc gttgctttgg ataaatggta ctttcggtgt acgcagtgca tggagcacta
    28981 aggtttgtgt ccatagtgat tcgacaaacc atcctgcatg gaataatgcg atgaaaatca
    29041 ctcgctgtga actatccaat gtatggaaac ttccgcccac tacagcagga caaataacaa
    29101 aatacatcaa caagtaagta gtaatatcaa atatcgaact tgttggacca aagtaaacca
    29161 tgaattcccc aatactagat gcattccatt tttttggctc gtccaaatat tctttatcca
    29221 tccgatccca tggcaaggaa atgcaggaaa catcatagat cagattcaaa aacaaaagtt
    29281 gtaaaggcag cattggtaaa aatggcagga acgtacttgc aatcagcacg gaaaacatat
    29341 tgccaaaatt agaacttgct gtagccttga tatatttcat gatattccca aaagtttctc
    29401 gtccagaaag aaggcctctt tccaaaatcg tcaaatcttt ttctaaaagg atcacgtctg
    29461 cagattcttt cgcaatatcc acagctgtat ctacagaaat accgatatca gccactttca
    29521 ttgcaggagc gtcattgata ccatctccta aaaatccgac agtatgacca tttttacgta
    29581 aagctgtcgt caaacgtgct ttttgctgag gattcaattt tacgaatact tcatggtctt
    29641 cagctacttg tgctaattca tgatcactca tttccgagat tttctcaccg gtaaccaatt
    29701 cattgatctc tagacctact tgacggcaca ctgaacgtgt aactaattcg ttgtccccag
    29761 tcagaacttt tacagctaca ccatgttctt tcagagcttt caacgcttgt ttcgttgttt
    29821 cttttggtgg atcaaggaaa gcaagataac caatcaaaac catgtctgac tcatctttga
    29881 ctgaaaattc tccaacgacg cttggattgg tcttttgtgc gacaccaatc actcgtaagc
    29941 catcttcatt aagtgactgt acttttgcaa gtacggcttc ttttcgttct tttgttaatg
    30001 gtgtaacagt accgccaaga tcaataaatt tagaaatgtt cagcatttct tcaatcgcac
    30061 cttttgtgat catttgtgtt ttaccagctg gatcagcaac cacaacactc atacgacgac
    30121 gttcaaaatc aaaaggaatt tcatccactt tttgataatt gatcttatct gtatctaaag
    30181 tttctgttgc ttcatcaatg atagccacat ctaacaaatt tttcagccct gtttgatagt
    30241 agctatttag atacgcatgg cgcaaaacac gatcatcttc atttccttca caatccatat
    30301 gatattcaag aatgatttta tcttgtgtca atgtccccgt tttatccgta cataacacat
    30361 cgattgcacc aaagttctgg atggcattca aatttttgat cactgttcct tttttggcca
    30421 tcacacttgc tcctttgacc aaattcgtcg taacgatcat tggaagcatt tcaggtgtta
    30481 gaccaactgc tacagatagt ccaaaaagaa aagcttctag ccaatcccct tttgtaagcc
    30541 cattgatgac gataactgct ggagccatca atgacataaa tttgatcagt agcatggatg
    30601 ttttatggat gcctaattca aagcttgatt gaattggttt ttcagatagc gtttctgcta
    30661 catgaccaaa tagtgtttca tttccaacag aaacaatgat tccttccgca cttccactga
    30721 tgacattact tcccataaag acaagatttt cgtaacttgt ttcgctttgc tgatcgtctt
    30781 cacatacttt cgcatgcttt tctactggat agctttcccc tgtcaatgct gcttgggaaa
    30841 tgaataaatc ctttgcggac aataaacgca tatccgctgg tatcatatcc cctgctgaaa
    30901 gccgaacaag atctccacag acgatttctt ccataggaat ctctgtgtac tttccattac
    30961 gttttacagc tgccgttact ttcacaagtg atttcagttt ttcagccgct tgattggaac
    31021 gtacggactg aatcaacgtc attgtcccgc tgacgataac catagtgaag ataatggcta
    31081 caccgaaaag atctttatct ccaggagctg ctaatacata ttccgtgatg aatgaaataa
    31141 ttcctaatgc gatcaacact aatgtaaatg gcgtgatgta tgctttcaat atttctacaa
    31201 tgaatggtgt ttttttgcca tatgaaatcg cattttcacc gtaattttct cttgaacgtt
    31261 cgatttgttc ttctgtcaat ccatttgctg atgcatggaa tagttcaaat aattcttgtt
    31321 tcgtttttcc agcaaaagct gcatagattt tttgtgtatc tttctttttt tccatctcaa
    31381 tctctccttt gtgtccaaaa gacagctgtt ctcgctgctt ttggtcttta gctattcatc
    31441 ggatcgatag agaaaaaact gaaaggggct gagaacagat agataatagc cctggccttt
    31501 cctctagatc cttgtttttc gaatgactgt catccatttg ttctcatctc ctttactaag
    31561 taattttaat tcatgacttc caatcatttt tcgaatagtt atttttccaa ttagaccacc
    31621 tcctttttat ttttcaccga tggggatttg cggcaacaaa aaaacctctc gccaaatact
    31681 cagcgaaagg tttgaaaaag catattaaaa aaagcttctc agatctcatc gttgagtttt
    31741 gacactgtac aacgtaaaaa gcagatacct gcttttagct accttatgaa aagccttatc
    31801 tcgacaattc ctgttctacc cattggcgtc tctcgacgtt tttgggcagt agcctatgtt
    31861 tgtataggag cctcacctaa caaatcttat tcggttttcc ttcgttaata taacaactaa
    31921 aaaagaggat gtcaaatcaa ttttccatgt ttttcatact ttttttaaaa tacacacgtt
    31981 atattcctgt ctcacgcggt tttatttgtc tcattttcca cctcccgcta taatagaaat
    32041 atagtaggaa acgaggtgct gttatggaaa gaacacttgt tattatcaag ccagacggcg
    32101 tgagacgcca tttagtcgga agcatcatcc aacgttttga agcaaaggga ctggccattg
    32161 ctgaaatgaa gtttgaaact atgactcctg aattagcaaa agaacattat cagcacttga
    32221 ctgagcgcag tttttttgat gaactgatcg attacatgac ttccggtcct gtcgtttatc
    32281 ttgtgctggt cggcgaggaa gtgatcgata tcgtccgtaa gatggttgga gcaacaaaag
    32341 ctgccgatgc tgttccaggt acgatccgag gagactacgc gctgccgggg actgaaaaca
    32401 tcattcacgc ttctgattcc cgtgatgctg cggtaaaaga gatcgcccgc tttttcccgc
    32461 cattcgatat aaacaaaccg tctgaaaaag cggcgaagtg atacaaattc taaactgctg
    32521 gtctagttgc tgggttcagc aatggccagc agttttttct ctaaggacct ccgttgattc
    32581 tttcctaaca tatattcgag cactgtgaag aattcttggt agtctttcgt cttttcttcc
    32641 cctaaagcag cagaaatcaa tctttgataa taatctgcca tcaatgtttc atagatcact
    32701 gtacttcttt ctttatgtgc taagctccgt ttcatatctt cattcacact acgtgccttt
    32761 ttcaaccgac cattttctat ataaaacgaa gtcaggttca ttaaaaaagt aaagagatac
    32821 tgctcatgat tgttcaactg tgctaatcgt cgcattcttt ttttgatttt caaataattg
    32881 ttctcaatga accgatcact gaatatccaa ggaaaatcag ctagaataga tagttcaaat
    32941 tgaccatagt ctggtatctg catcaagtat tcttcaatga ttcggcattc ataacgtaaa
    33001 aattcaaatt ctgtctcaga tacttctgtt ttttcgacca tgtgaagatt caaaaccaaa
    33061 taatacagat cttctgtttt cttaaaatgc ctacggttat tgctgatctc tttataagga
    33121 tcaaagctgt cttcttgtac ccgatctagc attcgtcttt ttttctttaa ctttattggt
    33181 tcatccagct ggtttcgcat ccattcatat tctgcaagtg tcatgttcat tcgctctaaa
    33241 aatgatctca atgttacaaa tgacattttt ttcactgaat ttgtctcaat cccgactaga
    33301 gaagtcttaa aacagattcc ttccgctaat tgggactgtg tcaacttctt gttgactcga
    33361 agtttcttga tcaattcacc atcatacata atagttctcc tttttaattt aaatttttcc
    33421 acattcaata aatagatacg ttaaaaagga aaaatacacg aaaaaaataa aaaaatgttt
    33481 ttttcataaa aaataccaac cttcaagcat tagaatgttg tctaactact gaaggttggt
    33541 ttgattgttt attgattatt tttttgctgt tcaacgtctg ttcttgttac tggatataag
    33601 ttggttgttg ttttattacc attttttgaa aagacacttg tcgaatgttc gcctttttgc
    33661 ttttcgattg cttcattacg ttccgcttca tttttatagt catatttttt cggatcaatc
    33721 gtctcaaatc cgtttggcac ataaaaccgc aagagatttt cctgattcag cttatctgaa
    33781 agacttaacg cagtcttgac tttttcctga tctttggaga tttcctcatc gattcctgct
    33841 gctttcgtat cgatgatttc tcctgtctga ttattgtaag cttttcctcc taggacggtg
    33901 tatttgggtg tcacaaagtt cccatttcga aaagcaacta cttgatcatg ctgagaagat
    33961 aataagtctg taccaaaatg aagataatct ttatcatcga ttcccaatag atgtagtaat
    34021 gtcggcaaaa catcgatttc tccaccgtat tcatgattga ctgtcccttt agtataacca
    34081 ggcatatgga tcatcaatgg cactcgttgc atctgtgcgt tgtcaaattc atcccatgta
    34141 tctggatctt taccaagagc gcttgctaaa tctttattat ctgtattcga gatcccaaaa
    34201 tgatccccgt aaatcacaaa gattgaattt tggtaaatac cagatttttt caaatacgta
    34261 aaaaattgtt ccaatgattg atccagataa tgtgccgttc gaacataatt atctactgtg
    34321 ctattgccag tattcaaaga tggaaagtcg aaattcttgt catccgtata ataaggcgtg
    34381 tggttggtta cggaaagaaa tttcgtgtaa aacggctgtt gtagatgctc aagatattgg
    34441 gcagattctc tgaataaatc tttatctaat atcccataac ctaacgtttc gtcggattca
    34501 tcaaaataag atcgatcaaa gaaattgtca taacctaagt ttttatatac atgatctcta
    34561 ttccaaaaac tagctacatt cccatggaaa acagcgcttg tatagccttg cttttgtcca
    34621 aggatcgctg gtgcggcttg aaagacattg tctgacccaa gttctgtgaa taatgagcct
    34681 tgaggtaaac caaatgtgcc agtttccaac atattttcag catcacttgt ctttccctgt
    34741 cctacttcat gaaagaaatt gtcaaagctg atcgttgctt gattctggaa aatactattt
    34801 aaaaacggtg tgacttcttg tccgtctacc ttcatattaa tcaaaaactg ctggaaactt
    34861 tctaaatgga gaacgatcac atttttccct ttagcgatcc caaatgtttc gggatttggc
    34921 tctgcataat gtttctttgt ataatctaaa acttcatcaa tcccattact gcttgcatgc
    34981 gcgcgaacac tgctagtcat tcctgttttg attccgtcat aaatagtata cgcatcgatt
    35041 cctagatatt tgacaatata tgaacggtca aatgttcgct gcagcaattg tggacggttg
    35101 gcttcgctca gcgctagatt tcctgaaaaa ataagccctg aaagacaggt aacagcgata
    35161 gccatcggtt tgccgacagg gttgcttttg ataggtattt tcttgacctt caaccaaacc
    35221 agtagcccaa tgaacacagc gatatccagc cagtagatga catcatgggg cttcatcaaa
    35281 gaaaaggagc ttcctgacaa tccttgcgac actttcgaaa agcctaatac agatttgact
    35341 gtaatgaaat ctgtgaattc ccgataaaaa ataatattca agtacaacaa aagcgtattt
    35401 aaaatatcaa tgatcaaaag aatagctaac gctggctttg gctttttaat atacaaagaa
    35461 aggccaaaaa acaataaggt agtcgcaatt gggttgatcc acaagataaa gtactggatc
    35521 gtaccttcca cacctaatga aaaatctgca tagtaggcaa tgatcgtctt cagccagaaa
    35581 aagaaaacag ctgtcaaaac gattgctaaa cgattttggc acaatttttt aagttgtgtc
    35641 acgtatatca cttctctcta ttcacatttt ttcttatttt gctcctgaaa aatgaaaatt
    35701 tcctaaaaaa gttgttatct taagattttt ttattctttc taaagattat tccgtccact
    35761 tttcacagca taaaaccgct gcgatgtaag cgattaaact aatgaagaga taaaagtctt
    35821 gtggtgaccg cttcactcca cggtattcaa aagccagttt ctcggtattc gtacaaaaaa
    35881 agaggctgtg acaaaattct tgtcgcagct ccttatttct tgatgcagga cagctttttc
    35941 acaacttctt ccttaaacgg tgttctcctg ccaactcctc ggccacaagt cacaatattt
    36001 ataaaacatg agaagctgtt ttttgaaatt gttccttgtg gctcagagtt aaacggcagg
    36061 ctcaagacct cttgatacac ggtgttcaat cagctgaccc tcggtattag attatgtcag
    36121 gacgctaatt ttacaacctc ttggtaaacg gtgttcaaaa gcttgcatct gcggtaataa
    36181 gcccaaccaa acgaaaaata taaggagcta ttttttgaaa ttgctccttg tggctcagag
    36241 ttaaacggca ggctcaagac ctcttgata
//
LOCUS       DADGHT010000019        34954 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.019, whole genome shotgun sequence.
ACCESSION   DADGHT010000019 DADGHT010000000
VERSION     DADGHT010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.019"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            153..1859
                     /locus_tag="JX887_000816"
     CDS             153..1859
                     /locus_tag="JX887_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAX1256824.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2017..2919)
                     /locus_tag="JX887_000817"
     CDS             complement(2017..2919)
                     /locus_tag="JX887_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1256825.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2916..3620)
                     /locus_tag="JX887_000818"
     CDS             complement(2916..3620)
                     /locus_tag="JX887_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAX1256826.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            complement(3651..4292)
                     /locus_tag="JX887_000819"
     CDS             complement(3651..4292)
                     /locus_tag="JX887_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAX1256827.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4330..4644)
                     /locus_tag="JX887_000820"
     CDS             complement(4330..4644)
                     /locus_tag="JX887_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256828.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4632..5261)
                     /locus_tag="JX887_000821"
     CDS             complement(4632..5261)
                     /locus_tag="JX887_000821"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAX1256829.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5268..5984)
                     /gene="pyrF"
                     /locus_tag="JX887_000822"
     CDS             complement(5268..5984)
                     /gene="pyrF"
                     /locus_tag="JX887_000822"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAX1256830.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5981..6913)
                     /locus_tag="JX887_000823"
     CDS             complement(5981..6913)
                     /locus_tag="JX887_000823"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAX1256831.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6910..7686)
                     /locus_tag="JX887_000824"
     CDS             complement(6910..7686)
                     /locus_tag="JX887_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAX1256832.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7740..10925)
                     /gene="carB"
                     /locus_tag="JX887_000825"
     CDS             complement(7740..10925)
                     /gene="carB"
                     /locus_tag="JX887_000825"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAX1256833.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10930..12006)
                     /gene="carA"
                     /locus_tag="JX887_000826"
     CDS             complement(10930..12006)
                     /gene="carA"
                     /locus_tag="JX887_000826"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAX1256834.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12011..13291)
                     /locus_tag="JX887_000827"
     CDS             complement(12011..13291)
                     /locus_tag="JX887_000827"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAX1256835.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13310..14236)
                     /locus_tag="JX887_000828"
     CDS             complement(13310..14236)
                     /locus_tag="JX887_000828"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAX1256836.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14249..15532)
                     /locus_tag="JX887_000829"
     CDS             complement(14249..15532)
                     /locus_tag="JX887_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAX1256837.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="JX887_000830"
     CDS             complement(15546..16085)
                     /gene="pyrR"
                     /locus_tag="JX887_000830"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAX1256838.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16320..17231)
                     /locus_tag="JX887_000831"
     CDS             complement(16320..17231)
                     /locus_tag="JX887_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAX1256839.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17228..17692)
                     /locus_tag="JX887_000832"
     CDS             complement(17228..17692)
                     /locus_tag="JX887_000832"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAX1256840.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17697..18395)
                     /locus_tag="JX887_000833"
     CDS             complement(17697..18395)
                     /locus_tag="JX887_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAX1256841.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18382..18768)
                     /locus_tag="JX887_000834"
     CDS             complement(18382..18768)
                     /locus_tag="JX887_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256842.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18915..20585)
                     /locus_tag="JX887_000835"
     CDS             complement(18915..20585)
                     /locus_tag="JX887_000835"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAX1256843.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20768..21001
                     /locus_tag="JX887_000836"
     CDS             20768..21001
                     /locus_tag="JX887_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAX1256844.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21100..21531)
                     /locus_tag="JX887_000837"
     CDS             complement(21100..21531)
                     /locus_tag="JX887_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAX1256845.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21610..22023
                     /locus_tag="JX887_000838"
     CDS             21610..22023
                     /locus_tag="JX887_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAX1256846.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22061..23209)
                     /locus_tag="JX887_000839"
     CDS             complement(22061..23209)
                     /locus_tag="JX887_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAX1256847.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23331..23927)
                     /locus_tag="JX887_000840"
     CDS             complement(23331..23927)
                     /locus_tag="JX887_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAX1256848.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="JX887_000841"
     CDS             complement(24127..26769)
                     /gene="alaS"
                     /locus_tag="JX887_000841"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAX1256849.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27157..27588
                     /locus_tag="JX887_000842"
     CDS             27157..27588
                     /locus_tag="JX887_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1256850.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27633..28982)
                     /locus_tag="JX887_000843"
     CDS             complement(27633..28982)
                     /locus_tag="JX887_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAX1256851.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29052..30215)
                     /locus_tag="JX887_000844"
     CDS             complement(29052..30215)
                     /locus_tag="JX887_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256852.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30344..30667
                     /locus_tag="JX887_000845"
     CDS             30344..30667
                     /locus_tag="JX887_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256853.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30850..32199)
                     /locus_tag="JX887_000846"
     CDS             complement(30850..32199)
                     /locus_tag="JX887_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1256854.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32268..33221)
                     /locus_tag="JX887_000847"
     CDS             complement(32268..33221)
                     /locus_tag="JX887_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAX1256855.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33323..34513)
                     /locus_tag="JX887_000848"
     CDS             complement(33323..34513)
                     /locus_tag="JX887_000848"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAX1256856.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9948 a         7640 c         6119 g        11247 t
ORIGIN      
        1 taaaaatttg gatttcaacg atagaaacac tgttttttat gtaattagtc caagattttt
       61 ctagactttt gctttactat tcggccaaat tggtttttct tctttttttc gttataatga
      121 atatacttat gaaaagaaat gaggaatgaa ccatgtcctt tgatggtgta tttacccacg
      181 cgatggtcaa cgaattgcgt gaaacgttac tatctggccg gatctcgaaa atccatcagc
      241 cttatgaaaa tgaaatcgtg ctggtgattc gttcacgcgg caaaaaccat cgattattat
      301 tatctgcgca cccaagttat gctcgtgtac agattaccca aatcgattat cagaatcctg
      361 ataatccgcc taacttcgtg atgatgcttc gaaaatattt ggatggcgct attttagaag
      421 acatcgaaca aatcgaaaat gatcgagtga tccatttcca ctttgctaaa cgaaacgagt
      481 tgggtgatct acaaaatatc atattgatcg ttgaattaat gggacgtcat agtacgatcg
      541 tcttagttaa tcgagaaact ggaaaaatac tggatgcgat caaacacatt ggaagctctc
      601 aaaacactta tcgttctttg cttcctggtg tagaatatgt tgctccgcca aaacaagagg
      661 tcttgaaccc atttagctcc gagaaagaaa aaatctttca gcggctttcc caaactgaac
      721 tagatccaaa agcaatccaa cgtcagtttc agggaatcgg tttcgatatc gctcaagagc
      781 tgaccaaaag attactggaa cgtcctaatg aaaagatggt tgtatgggac gaatttttct
      841 cagccatcag ccatcagcct attcctactt tttacgaaac ggaaaataaa gattttttca
      901 caccgattgc ttatcaggta ttgtccgaac aggcatctgc tgtaacagct tatccaacac
      961 tcagtcaatt attagatagc tattatcacg aaaaagcaga gaaagatcgg gcaaaacaac
     1021 aaggcggaga actgattcga aaaatcgaaa atgaactaaa acgaaataaa aataaattga
     1081 aaaaacgtga acaaacactc aaagaatccg aaaacgctga gaattaccgt agaaatggcg
     1141 aactacttac tacttttctg acacaagtac cacgcggcgc aaaagaagtt gttttaccta
     1201 attattatga agaagatcgg ccaatcaaaa tagcactaga tccggcattg acaccaaatc
     1261 aaaatgcaca gaaatatttc catcgatacc aaaagctgaa gaacgctgtt aagctgattg
     1321 gcgaacaaat ccaagaagcc aaagatgaaa tccaatatct tgaatctgtc ttatctcaac
     1381 tggaaattgc cggcccaatg gatatcgaag caattaaaga agaattgact tcagaaggat
     1441 acctgaaaaa gaagaactta aaaaaacaaa aacgtaagaa accatctcag cctgatcaat
     1501 acttttcttc tgacggaacg ctcattcttg ttggtaaaaa caatcttcaa aatgaccagc
     1561 tgacaatgaa gacagctaaa aaaaccgact attggcttca tgcaaaaaat atacccggtt
     1621 cgcacgtcat cattaaaagt gacaagccct cagatgaaac aattacagaa gctgccgagt
     1681 tagctgccta tttttcaaaa taccgatact ctgcccaagt gccggttgat cttgtacagg
     1741 taaagcatat ccgaaaacca aatggcgcca agcctggtta tgttatttat gaaaaccaaa
     1801 agacgattat cgtgacacca gaagaagaaa aaattacagc tatgaaacaa aacaggtaat
     1861 caatgagtgt ttctagaatc atatttgcgt actttcccac aacagcaatt agttataaat
     1921 tgtttgctac aaaaagagga gttgtgacaa aattctgtca caacccctct tttttgatca
     1981 acggtgttca ataaacagcg ttctcatctg cttttcttag ctctgctggt ccagtaaccg
     2041 agtaagctct ttgataaatc tttgagcgat ttcactgagc ggacgtttcg ccgaataaat
     2101 gatataaaat tcatttagtt cgccttctgc caaagggatt aaccgcaagt gctcgcgaat
     2161 ccctccaatc acaataccag atcctgaagc gtaagcatca gtttcaagaa cgatattcat
     2221 caaagtacct cgatcactcg tataaatcac tgtttcttga tcagggatct cgataaggtc
     2281 ttcataaaaa tacgggaaat tatttccatc ctgtgtaaaa cgaacttgag gataagataa
     2341 caattcttct ttggtgatct ctgcgtgttc agctaatgga tgtccttgcc ttaaaaaaat
     2401 atgcgttttg aattttccaa tgctgcggcc acttagctct ccttgttgta aatatcttct
     2461 gataccagct tgattatgct cattcatata aataatgccg atctcactgt gctgctcttt
     2521 gacttcttcg atcactctcg ctgttgtcgt ctccatgatc cgaaattgtt tgatctcgtc
     2581 tttgaattcc tcgagtagct gtgcggtcaa aggacctaag aaatcataat gctgggcagc
     2641 gatcgaaaaa ttgtctctct tttcactcgt tagatagtga gtttctaatg tatcaagctg
     2701 gaccaatatt ttctcggcac gatttaagaa gtcttgccct tcttctgtta aatatgcccc
     2761 tcgattcgtt cgagtaaaca gcgtgatccc taactcggtt tctaattctt tgataccagc
     2821 tgaaagactt ggctgggaga caaacatttt ctttgccgct tctctgaaac taccattgtt
     2881 tgctacagcg accacgtatt tcatctgctg aatattcatt gctcaaactc ctcgaaataa
     2941 taaatttctc ttccattcaa gggctggatt ggtcggttgt tcggtcgagc atactgacca
     3001 tcgaagggga gaagaaactc ttggttcagt tttcctacat gatccattac aaaccattgg
     3061 attggcccgc tggtaggcgg agttgtcaat gagccaatat aatggaaatg gcttttttgc
     3121 tccggaaaga acacatccgg atttacccaa tgctcatgtt tttctaagtt ccaactttcc
     3181 ccattttctt gattatacag ccaaccttcc tgtaccatta gctggtacat gacacccaca
     3241 actagattct cttttttgct gttcatatga acaaaatgaa attcaatatc ttcctgtttt
     3301 ccgttgatga tatgttcaga aggcaagtgg aaatgaatat ctgtcaaata atagcgttct
     3361 ttcttgaact ctacataact gagttggtca aaaggtacta aatgaatcgt gtttttgaat
     3421 tccttgtcag taaaccgttg cttttgataa tgaaaggaaa gcgtgtctcc ttctattttg
     3481 gtttcttccc ccttggtcaa atgaataggc gactgcaatg gaaattccgc acctctcgca
     3541 aaccaatcac ataaactcgc ccaattttcc ggacctttgt ctccagaata gccccattcg
     3601 acatccatat tctttttcaa ctatacttcc ccctgcatct catatcattt ttatttttct
     3661 tctttcttta caatcgttga gacggtttct aaaaacgcct cttttccata aaattcctgg
     3721 ttcaatagtt ccggaaatat ctctttaaag aaatactgaa cagaaggccg atgttcaaag
     3781 cttttaatcg tagtcactgc ctcaatgaac atctccttat aaactttttc cgggttattt
     3841 ttgatgattt catcaaaaga ttcataaaga aggtcaacct tatctgaaat ggctaatagt
     3901 tctccttcta cggtttcatc ttttccttcg aacaaccgac ggcgataaac ttcttggaac
     3961 tcagctggaa tctcttggtt gatgaattcg tccgtcatct tttcttcaac tgtttgcagc
     4021 atccctctta actctttgct tgcgtatttc accggcgttt tgatatcacc aataaaacgc
     4081 tctgtgtagt catgattcaa tgatttttca tagagcagtt tccaatcgat cggttgtcca
     4141 ttcgcttctt caatgtctcc tagaacttgc gcaatagatg ctacacgata cgaatgtgct
     4201 gcaactgtat gctctgtata tttaaaaaat ccaggtgccc ttgtgatcgt ctctaaattg
     4261 ttcaatccta aaataaattc attcaacccc ataaaagtta cctccctttg agatttcttt
     4321 ttccgaatat catatcatta aataactgat attcgcaaca tttccgctct ttaccatttt
     4381 tgaaacagct cccttaccaa aaaatagaga aaatctatat ataatagaaa aaagagaaga
     4441 gattattctc ttctttctgc taaccagtct tagaaaaatg aattttaaaa aaatcaaaaa
     4501 ctgatcacga tagaagtttc ttttcatacc tgatgaaaag atgcttctcg caatcagttt
     4561 ttggattttt gctattccaa ttgatgattc tggagacaca aatcggattt ctctatcttc
     4621 atcaagcgcg cttaaatctg ccaattttca ggatcttttt tccattcttt tagcagagtt
     4681 aattcttgct catcgatata acgatcttct aaagctgctt caatcaatac agaataattg
     4741 gtcaacgtca taagagggat ttcggctttt tcgaaatttg cttttccttt tggcaactca
     4801 tacgtaaaga tagccgcaac accaaggata tccgcacctt ctctttttgc tgcttcagct
     4861 gcttccaaga cacttccgcc tgtagaaatc aaatcctcga tcacaaccat cttctgacct
     4921 tcaaatatac gtccttcgat ttggttacct ttcccatgat ctttcgcctt acttcgaata
     4981 tagaccattg gcaaatccag tatttccgct acccatgcgg catgagggat tcctgctgtt
     5041 gcagttccag caatcacttg tacttcaggg taagcttctt tgattttgct tgctaatcct
     5101 tttgcgatct cttttcggac ttttggatag ctcatcgtga ttcggttatc acagtaaatt
     5161 gggcttttga ttccacttgc ccatgtaaaa ggattacttg gatttaaaaa tactgcttca
     5221 atttctaata agtcttttgc gatactttgt tcaacattca ttttaggtta gctccattct
     5281 gtttgaatcg tttgatatgc tttataagga ttagttgact gagtgattgg tcgacctata
     5341 acgataaaag ttgagccgat cttttttgcc tgagaaggtg tgactactct tgtctgatct
     5401 cctgcgactg ttccttctgg tcttataccc ggagttaagc aaacaaattc gtctcctgcc
     5461 atttctttga tcgcttctac ttcccaagca gaagaaacca caccatctaa tcctgctttt
     5521 ttggcacagc tagcataatg gatcacactt ttttctaaag aaacttcgat tagttgatcg
     5581 gcatgcattt cttcttcact tgtagaagta agctgagtga tagctagaag tagcggacgt
     5641 tttccacctt ctggagtccc ctcttctaat cctcgcattg ccgcctccat catacgaata
     5701 ccgccagcgg catgaacaca ggtgagatca acaccaagct ttgccaatcc ccgcattgct
     5761 ttttcgaccg tattcggaat atcgtgaagt ttcagatcta aaaatacatt atgaccagcc
     5821 tcttttagat aacgtacgat ttcaggtcct tcttggtaga acaattccat tccgattttc
     5881 acaaacaatt tttcttcttt cgggaaaaat cgaagaaagt cttctacctc ttgcctagtt
     5941 gaaaaatcta atgcaataat tggtcgttgg tctagttgat tcatcgttca cgttcctctc
     6001 tcacttcttt gattaatctt tccagcgatt cgatgcctag ttcgctcatt cgcacaggga
     6061 gctctttaat tagtttagga cagatatacg gatcggtgaa attcgcggtc cctatagcta
     6121 cagcacttgc tccagccata aacatctcaa gaacatcatc cactgtctgc acgccgccca
     6181 tcccaatgat tggaaggctg gatatacttg ctacttggtg aatcaaacga atagcgacag
     6241 gcttgattgc tggtccggag agtccacctg tttgattggc taaaatcggt tttcttgtct
     6301 taaggtcaat ccgcatacca agaagagtat tgatcatcgt aaacccatct gcccctccag
     6361 cttcgattgc ctgagcgatt ggaacgatgt ctgttacatt tggggacaat ttgacataga
     6421 caggaacaga agaaactttc tttactgctt gtgttaattg aaaagcaaca tcagaatctg
     6481 ttccaaaagc aattccgcca tgtttgacat ttgggcaaga aatgttcagc tcgattgctt
     6541 tcacatttgg tgcttcgcca attttgctac aaacttctac atagtcttct tcacaagcac
     6601 cagcaacatt tgcgatgatg ggtaactcat tgtactcctc taattctgga agaagtttat
     6661 gcataacaac gtctagacca ggattttgca aaccaattgc attcaacatg ccagatggtg
     6721 tttccgccac tcttggcgtg ggattgccaa agcgggcatt tggagtcgtt gccttgacca
     6781 tgatcgatcc aagctgattc aaatcatagt attttccgta ttctttgcca aaaccgaaac
     6841 agccgcttgc cggcatgata ggatttttta attctaggcc aggaagtttg accgctaaag
     6901 gattctcatt catataatta cctctcctat tttaaaaatc ggtccttcgt cacaaacttt
     6961 cacacttttt gttcctgttt catcttccgg cgtatgacaa acgcaagcat agcaagcccc
     7021 tatcccacat gccatgcggg attctaatga taactggaca ttttgatgcg aagaaaacag
     7081 ctgttccact gtcttcaata acccgtttga accacatgca aaaacagctg taggttccgt
     7141 cttcgttcct aacaataaat taccgacatt tccgtgcata ccgtatgttc catcgtcagt
     7201 agcgattctt gtttctccta gacgattaaa ttctttttca taataaacga cttcatgtgt
     7261 ggcaaaacct aaaaaatgcg ttggcttaat tcctttttcg actaactgtt ttgataactc
     7321 atatagagga gggacaccga ttcctccacc gattataaat acttcgtctc ctgtatgaag
     7381 attggacaaa tcaaaaccat tgcctaaagg acccatgaca tctaaatggt ctccggcaga
     7441 aagagtagag aagactctag tcccctcacc ttccacccga taaatgatac ggcaagtatt
     7501 tgtttcgtgg tcgatatgat tcaagctaat cggtcggcgt aatagcaagt ctgcacgcgg
     7561 cacgagaata tgcaagaact gtcctggttg ctgcatttct tttactagat cacctttcaa
     7621 tgtcatttca aaaatctttg gtgccagctg tttttgctga acgatttcca tcatttcttg
     7681 tttcatctgt cccctcctgc aacggttttt cgtctttttg tcttaacatg tgctcgccgt
     7741 taaatagggt tagttgaaaa agcacgggat tccatcactc gaacgatcgc atctgctgtg
     7801 tctaaagaag taaacaatgg aataccatgt tcaactgctt ctcttcggat gatgaaaccg
     7861 tctttagaag catttccccg atctttatca atcgtattga caaccacttg tgttttacca
     7921 tctcttatta agtcgactac atttttttct gctgcttcct cagaaatttt cgctactgtt
     7981 tcaacgacca gaccattttt ttcgaaataa gcagctgtat gtttcgttcc tatcagacta
     8041 tagccaattt ctgtaaaacg tttagctaat tctagtgctt cttcttttgt ttcgtccgca
     8101 atcgtaaata atacggctcc atattcaggc aagtgtaatc cagaagcttc gaatgccttg
     8161 tacaaagctt tgtctaattg tctgtcagat cccattactt ctccagtcga tttcatttca
     8221 ggccctaagt aagtatcaac tttctgcaat ttcgtaaaag aaaagacagg tgctttaaca
     8281 tgaacttctt ttgtttctgg ataaagtccg ttttcataac caagtgtctt tagtttctct
     8341 cccaaaatag ctttcgtcgc aatttgtgcc attggaattc ctgtcacctt acttaagaat
     8401 ggaacagtcc gacttgctcg aggattgact tcgatcacat aaacctcatt ttcatggatg
     8461 acaaactgga tattcatcat cccgacacaa ttcaaaccta atgctaagcg gatcgtgtaa
     8521 tcttcgatcg ttttcttgat cgattcagat aatgtttgag gtggatacac agccattgaa
     8581 tcccctgaat ggacaccagc acgctcaata tgctccatga tccctgggat gagtactgtt
     8641 tcaccgtcac aaatcgcatc cacttcgcat tcaccaccaa gcaagtaacg gtccactagt
     8701 actggatgtt ctggagatgc tttcacagca tgttccatgt aatcttctaa atctcgctgg
     8761 ttttcaacga tttccatcgc acgtccgcct aatacatagc ttggacgaac aagaactgga
     8821 taaccaattc tcgaagcgat aaccacggct tcttctttac ttgtagcagt atcccctaaa
     8881 ggttgaggaa tatccaactc tttcagcgct tgctcgaata aatcacgatt ttccgcacga
     8941 tccaagtctt cgatcgttgt ccctaagatt tttacaccag cagcagtcaa aggttcggct
     9001 aagttgattg ctgtctgacc accaaattga acgattactc ctatcggctg ttctagctcg
     9061 atcacattca tcacatcttc gaaggtcaat ggctcaaaat ataatttatc cgaaatagaa
     9121 aagtcagtcg aaactgtttc aggattgctg ttcatgatga ttgcttcgta tcctgcctgc
     9181 tggattgctt tgacagaatg cacagtcgca tagtcaaatt caaccccttg tccgatacgg
     9241 ataggaccag atcccagtac tagaattgag ggcttttctg atcgtgaact ttcattttca
     9301 tattcatagg aactataaaa ataaggtgtt tttgattcga attccgctgc acaagtgtca
     9361 accatcttat atacaggaat caaatcattt tcttttctca tctggcgaac ggcttcttcg
     9421 tttatttccc acagctccgc cacttttttg tctgtaaaac cgttttgttt cgctgttttc
     9481 aatatcttgt catccaacgg ctgctgtttc aactgctgtt cgatttctac gatatgcaac
     9541 agtttatcta aaaagaataa atcgattttt gtcaaatccg ctaattcttc tatggtgtac
     9601 cctcttctaa tagcttcagc tacataaaac aggcgatcat cttgtgctcg aaccactttt
     9661 tggattaggt catcgtccgt gatgtctgcc aactcaggaa gttcgatatg gtgtgtaccg
     9721 atttctaaag aacgcacagc tttcaataaa gactcttcga tattccgacc gatagccatc
     9781 acttcaccag ttgctttcat ctgcgtgcct aaaagccgtt ctccgttttc aaacttatca
     9841 aacggccagc gaggaatttt agctacaaca taatctaatg caggttcaaa ttctgcaaaa
     9901 gtcgttcctg taacaggatt tttcatttcg tctaatgtta atccaagcgc tattttagca
     9961 gctagcttag cgatcggata gccagtcgcc ttacttgcta acgcagatga acgagaaaca
    10021 cgcggattga cttcaatcac ataataatta aaactatgtg gatcaagagc gagttggaca
    10081 ttacagcctc cctcgatctt aagtgctcga ataatcgaaa gagaagcatc acgaagcatt
    10141 tgatattcat ggtcagacaa tgtttgacta ggggcaaata cgatagaatc acctgtatgg
    10201 atacccaccg ggtcaaaatt ttccatattg cagacaacga ttgcattatc agccgaatct
    10261 ctcatcactt catattcaat ttctttaaaa cctgcaatac ttcgttcaat caaacattgg
    10321 gtagcggggg aaagacttaa tccattttct gatacgatac gtaattcttc ttcattttca
    10381 cacatacctc caccagttcc gcctaaagta aaggctggac gaacgatgac aggatagccg
    10441 attttatttg caaaatctac agcttcttct actgtattga cgatttcaga ctcggggatt
    10501 ggctgattca attctttcat caactgtttg aatagatcac gatcttctgc ttgatcgatc
    10561 gcagaaagct ttgttcctag aagttctatg ttcaattctt ctaaaatacc tgatgctgcc
    10621 agctccattg ccatattgag gcctgtctgt ccgcctaaag ttggaaggag agcatctgga
    10681 cgctcttttc gaagaatcct tgatacaaat tcaagtgtga tcggttcgat atatacttga
    10741 tctgccactt ctttatccgt catgatcgtc gcaggattag aatttactaa aaccacttca
    10801 tatccttctt cttttaaggc aaggcaggct tgtgttcctg cgtagtcaaa ttctgcggct
    10861 tgaccaatga tgatcggacc agatccaatc accataattt tcttgatatc tgtacgtttc
    10921 ggcatctgtt tactgctcct ttcctgcgtc catcatttcc ataaattcat caaataaatg
    10981 tagtgcatca tgcggaccag gggcagcatc tggatgaaac tgcacactga aagcgggata
    11041 atctctgtgt ttgactcctt ctactgttcc gtcatttact tctacatgag ttacgatgag
    11101 tttttctgga tcaatcgtgg cttcatcgac tgcatagcca tgattttgag aagtaaaatc
    11161 aattcttccg gtcgctactt ctcgtaccgg gtgatttaat cctcgatgtc cgaatttcat
    11221 tttataggta tctgcaccgt tggctaaagc aaataactgg tgaccgagac aaataccaaa
    11281 aatcggtact tttccttgga tttttttgat catttcgatt gcttctggca catcttttgg
    11341 atcaccaggt ccattcgtca gcatgactcc gtctggtgat agcgctaaaa tcgtctcggc
    11401 atctgtgtta tagggaagta ctgtgaggtt acagtttctt ttactcaatt ctcgtaaaat
    11461 actatgtttc aagccgaagt caatgacaat gactttccga cctgttcctg gacttggata
    11521 aggtttgtta gttgagactt gctgcacttg attggttgct agaacggttg ctttcagctg
    11581 atcaaatgca tgttcgaagg aatctccagc atcaactata ctagctttca tcgttccgac
    11641 ttcacggatt ttgcgagtaa gggcgcgcgt atcgatacct gatattccag gaattccttt
    11701 ttgtttcaaa aatgaatcta gcgtcatttg gtttcgccag tttgaagcta cacgtgcatg
    11761 ttcttttact actactcctt tgcatgttgg agaaatcgat tcataatcat ctctatttac
    11821 cccataatta cccaccatag gataggtaaa tgtaatgatt tgaccgttaa aactttgatc
    11881 agtgatagtt tcttgataac cagtcatact tgttgtaaaa acgatttctc cgaagacact
    11941 agcatctgca ccaaaagcct ttccttcgaa aactgttcca tcttctaata taagcaaacg
    12001 ttccatactt ttattctccc ttctgccaca caagttttcc gttgacaaaa gtcatttgtg
    12061 tttcgccttt tactttccag ccgataaaag gtgtattctc cccttttgat aaaaagtctt
    12121 ctttatcgat cgtgcaagtt tgtgtaatat caaaaactgc tacatcagcg ggggcaccaa
    12181 ccgttagcgt tcctgcattc aaaccaaaaa tctcagccgg tttaactgcc aaccaattga
    12241 tcacttgttc caacgtgaat cgaccagttt ctacaaaatg agtatagatc agttgaaacg
    12301 ctgtttcgct tcctacgata ccaaatggtg atttcatgaa actttggctt ttttcttcta
    12361 atccatgggg ggcatggtct gtagcgatgc aatcgatcgt accgtcaagc aagccttcga
    12421 tcaaagcttc tctgtcctcc cgtcctctta gcggcgggtt cattttccaa aagccgaaat
    12481 cttcgggaat atcttcgtcg atcaaaataa gatgatgggg tgaaacttct gctgttacgt
    12541 ggattcctgc tttttttgcg tctctgatta cacggacact ttctttagta gaaacatggc
    12601 aaacatggta atgaacacca gttgcttcag ctagcaacag atctctagca atttgagaag
    12661 actcggttac gcttaagatc ccgggaagac caagttcttc tgccttcttg ccagcgtgca
    12721 taacgccgcc aaataataaa gattcatctt ctgtatgggc tactagggct ttattgtttt
    12781 ttgcagcttc tttcatagcc agatacatcg tcccagctgt ttggacacct acaccgtcat
    12841 ttgtgaaagc aaaagcacct tcttcaatca gtgcttcttg atcaactaat ttctcacttc
    12901 gcagattttc tgtgattggc gcatactgca ataccttcac aactgcatct tttctaatga
    12961 tgtcatatac ttgtctcagc ttttctgccg tatcaggtac aggatttaaa ttcggcatcg
    13021 cgcatacagt agtgaaaccg ccacgagcag ctgagcgagt cccagcttcg atcgtctcct
    13081 tgtatgtaaa tcctggctct ctcaaatgaa catggacgtc cactaaacca ggtgtgatca
    13141 attgtccctt tgcatcaaac acttcatcaa attcggcttc tgagaatcct gtaccgattg
    13201 ctttgattcg cccatcttct atccaaattt ctgctggtgt cgtcatattt tttcgtgtat
    13261 tgatctgacc gtttttaatg agtgttttca ttttttcatc ctcctataat tacgcttttc
    13321 catttagcac tgcttctaag attgccattc tgacgaatac tccattgctc atttgctgaa
    13381 cgatccgcga ctgtaatcct tccactaatg aatcagctaa ttctacatca cggttaactg
    13441 gtgctgggtg cataatgatt gcatgttttt gcaacttctt cgcacgctca actgttaacc
    13501 catgttcctg atggtagcct tcttttgaga aactttcttt tccatcatgg cgttcgtgtt
    13561 gcacccgaag catcatcatg acatcaactt gatctagtag ttcatccaat ggcatataat
    13621 gtccgtacac ttcgaattca tcgtcgtacc attctctagg acctgagaag aatacttgtg
    13681 cgcctagacg ttttaacatc tgcatattgg atttagctac gcgagagtga gtgatatcac
    13741 ctacgatggc aactttcaga ccttcaaaat gaccaaattc ttcataaatg gtcatcaaat
    13801 caagcaagca ttgggttgga tgctgtccgc ttccgtctcc tccattgata atcgaacact
    13861 ggattgtttt actttgtatc agttcgtcat aatagttctc atcaccatga cggataaccg
    13921 ctacgtctac gcctaatgct gacatcgtca gtactgtatc gtatagtgtt tccccttttt
    13981 ggacagagct tgtgcttgct tcaaattcaa tcacttctag ccctagtttt ttctccgcta
    14041 catcgaagct tttatgtgtg cgagtactat tttcgaaaaa gaggtttgta gcaaagtact
    14101 ggcgcttttg cggagtccaa ttagcacctt gcttgaattc ctgccctctg cggatcaagc
    14161 ccataacttc ttgatcagta agtgcctcaa cggtcaataa atgctttaag ctgatacgtt
    14221 ctgatttgat gatcataatg tttcctcctt agttttcttc gcttcgtgaa gtttctggta
    14281 agataagatt taaaatgatg ccaagtacag ttgctaatgc cattgccgac aatgtaaatg
    14341 tgcctacttc aaagacgagt ccgccaattc ctactactaa gataactgaa gcaatcaaca
    14401 gatttttctt tttatcaaaa tcgattttgt tctcgattaa aatcttcatt ccacttgcgg
    14461 caattactcc aaataagata aaactgattc ctgagatgac tggtccaggg atacttaaaa
    14521 tcaaagcgct taattttcct acgaatccta aaatgactgc aaatactgca gctccaccga
    14581 tcacaaacac gctatggaca cgtgtgatag ccagaacacc aatgttttca ccgtaacttg
    14641 ttacaggagg acctccgaca aaggctgcca cgatttgtgc taatccatca cctgtcaacg
    14701 tcttatgaag acccggttct tcaaagaaat tacgtttagt tagtttattc aataccataa
    14761 gatggccgat atgctctgtc atcgtcacaa aagcgatggg tgccattgtt gtgattgctc
    14821 caagatatag ctttggttca tattgtacaa agggaatctc aaagttagga acagcaaacc
    14881 aggcagcgtc tacgattggc ttagtatcca cgattccaaa cagcaaggct acgatgtatc
    14941 cgctaataat acctagtaaa atcggaatca atccgagaaa acctcttagc cacatgttga
    15001 agaaaattgt taatcctaat gtgatcagcg ctacagcaat atacttgaaa tcatacgtgc
    15061 cctgattata catagcattt gttgctgcat ttgccgcaag tcccaacccg ataaccatga
    15121 tgactggacc gacgacgatt ggaggcaaga ttttatccag ccatgctgaa ccgatctttt
    15181 tgatgatcag cgcaacaatc aaatagacta atccagttgt gactgctcct tgtgcaatcg
    15241 ctggataacc atctgttttc atcaaaagct gcatcgctgc aatgaaagcg aagctgcttc
    15301 ctaagtacgc aggtatcttt cctttagtag taaataagta caccaatgta cctagtcctg
    15361 aactgactag cgcaatacct ggatcgatac ctactaagat ggggactaac acggttgctc
    15421 cgaacatcgt gaacaagtgt tgtaaactta atcctaccca atgtcctggg gttgggcgat
    15481 cgtggatatc taacaccacg tcatcattat gaaatccttt tttctccgac atgtttctct
    15541 ctcctctaat cttcctcttt caaaatcatg atgcgatctt gtccatcaag ctcttgcatc
    15601 tctactaaaa tctcttccgc ccgagatgtt ggaatgttct tcccaacata atctgcacgg
    15661 attggcaatt ctcgatgccc acgatcgacc aggactgcta atgaaatttt tcttggtctg
    15721 ccaaaatcca ttactgcgtc cattgctgct cgaatcgttc gtcctgtata caaaacatca
    15781 tcaatcaaaa taacttcttt tccttctaag gaaactggga tgtcagaaga atgaagttcc
    15841 ggttcttctg gattttcttt tttgtcatct cggtataaag tgatatccag ttctcctaca
    15901 ggaatatcga tatcttctag ctgcttcagg cgttcggcaa ttcttgatgc aatgtagatt
    15961 cctcgtgttt tgatacctac caatacgata tcttggatac tatggtttct ctcgataatc
    16021 tcataagtaa ttcgagtcaa tgctcgcttc atggttacct gatctactac ttcttttgct
    16081 tgcattttca ttccccctac ttttttgcat aaaaaaactc ctgccctaag aggacaggag
    16141 gaatgtttag actgagcgta tactgataca ctgatagcta tactatgtca atgagcaatc
    16201 tacttatggc gcaccatacg tatccttgct cccacccttc ttagcctcac gggactaaac
    16261 ttaaaggaat tctattaagt tttatgcttt cgttgttaat tactataccg ttatctaaat
    16321 taaaatgcaa tgttttttct taatttttct aaagtttttt caaaaacttc tggaagaggt
    16381 gcttcaaaga tcatcttttc gtttgtagtc gggtgcgtaa aacctaacat ttgcgcatgg
    16441 agaaactgac cattgccttt caaagttttc ttcggtccgt atactggatc tccagctaac
    16501 ggataaccga tatacttcat atgcacacgg atctggtgtg ttcttccggt ttctagtttt
    16561 aattcaacca gagtaaatcc ttcgaaacgt tccaatacag taaaatgtgt gacagccgac
    16621 ttcccatctt ctcttatcgc ctgcattttc cggttttcct tcgaacggcc gattggcgca
    16681 ttgatggttc ctttttcgtg aggaatctct ccatggacta aagcaacata tttgcgcaaa
    16741 gaggtcttat cttttaattg ctgagctaat gattcgtgtg cctggtcatt tttggcaacc
    16801 attagcagtc cggaagtatc tttgtcgatt cggtgaacaa tacctggacg aataacgccg
    16861 ttgatcgtag aaagatcctt gatatggtac atcagcgcat tgaccattgt gccatgcgta
    16921 tgacctgctg aaggatgaac gaccattcct tgaggtttgt ttatcaccgc tacatcttca
    16981 tcttcgtaaa cgatcgtcaa cgggatattt tctgggacca catctaatgt ttctggttcg
    17041 gggatcaaga cagtaatctc gtctccttgt tttactttgt aatttgcttt gactggctgt
    17101 ccattgacag aaaccgctcc atttttcagc cacagctgaa tttgcgaacg actgtaatcg
    17161 gtgaataaat tagtcaatac tttatcgatc ctaccagatt catggtgaat cgtcgtttta
    17221 agttctgtca tttttttctt tgatcctttt catctaaaat aatataaatt aacatacaaa
    17281 tcactccaca tacaagtgtc acatctgcta cgttaaaaat cggaaagctc ataaaatctg
    17341 tctggaacat atctactaca tagccaagac gaatacggtc gataaaattg ccaatcgcac
    17401 cagctagaat caaactcaat ccaatcatga accagcgatt acctttttca cgatttttaa
    17461 tcatcaatgt gagaatcaca acgactgcaa tgagtgtcac tatagtaaag aaccacatct
    17521 tcccttctag catactccat gcggctccag tgtttcgaat atgattcagt gacaaaatac
    17581 ctggtataag atttttcgtc tctccaagcg ctagattatc agtgatccac catttgacca
    17641 actgatccac tcctactagc aaagcgctga atatccaata aataattaac aaaaaatcaa
    17701 tccttttcta tttgtttata aatatcacga ggtcgtacga tcccgagcag attaccatcg
    17761 ggattcccat ctttagtgat aagtacggct tccaaagtcc cttgctcacg aaacatcgct
    17821 tcaacctcgt aaatatgtgt tttagctgga acaaaatgat aatttgtgta ctttccgttt
    17881 tggatgatca aatccaacgc tcgtttattt gttaaatcaa ccggaccttt ttggctttct
    17941 tttgctagcc aaaacccgat attacgtaaa gtaatcaatg ctacaaattt tcctttattg
    18001 tataacggaa attgtgaata ccttttttct gctactatct ttaacagttc aagtaacgga
    18061 agatcttgtt caaaacctgt tacacgtttt gcaaatcgag gcagcacggt ttcaggctga
    18121 atcagttctt gttcgatcag ctggattcgc ttgactgtcc aatcatttgg ctctgcaatg
    18181 acaaaatcga ctgcgatccg atcatggacg atcgcattcc ttaactgagc aagctgtaaa
    18241 agatcatctt cgtattttct gatcattaat tgttttcttt gagctaggcg tctgacaagt
    18301 tcggtaaatc ccatatttcg tgcatttccc atctcgtctc tcatccattt ttcgattcga
    18361 ttgaaactga ttaaaaaaag atcagagttt gccataattt tcctccttga tcaaatatgc
    18421 ccggtttttt atatagaaaa agaacgcaat caacacaata actgcaaaaa aactgaaaaa
    18481 taaattttgt aggaaaacgg cccccaaccc agttgctaga aataaaaacg gatagatttg
    18541 aagaatcaag taattcattg tgatcacata agcaggcttt gcttctttca ctgtataaac
    18601 ggggcttttt agccaataaa aggtgacctg catcgtaaag ggcacttcca gatcaagcgt
    18661 tatcttttgt tcatgactga gaacactgcg tttttcattg ttgattctta gctgaatcga
    18721 gctacccata ccgtaaaaac cggtttttct tataaatgtc gttttcatca taccctccta
    18781 ttatgcttta gtatagctca aaatacaata aagaaaaaga atgatcctag tgtaaacaaa
    18841 attaattccc tatcgtctaa aaaaagaagc tgtagtcaaa atacagctcc ttcgatggta
    18901 gattataatc aagcttaaaa caatcccaac acttctccgt catttgtcac gtccatattc
    18961 aatgcagcag gttttttagg caaaccaggc atcgtcataa catctccagt caaggctact
    19021 aaaaatcctg cccctaattt tgggatgatt tcgcggatcg tgatggtgaa atcttccggt
    19081 gcacctagca gtgaaggatc atcagaaaat gaatactgtg tttttgccat acaaatcggc
    19141 agtttgtccc atccattctt cgtaaactct tctatttgtt tttgcgcttt tttgctgaaa
    19201 acaacaccat ttcctccgta aattttcttg acgattgttt ctgtcttttc ttgtatcgtt
    19261 tcttctaggc ggtataatgg cttgtaatta gcttcttttc tatcaatcaa tcgtactaca
    19321 gcttttgcta aatcaacgcc gccttctgct ccatctgccc atacactcgc tctcttggca
    19381 agaatcccct gattttcaca caagtgctcc aacagtgtga gttcattgtc tgtatctgtt
    19441 acgaattcat tgattgcgac gatcacaggt agctgatatt gttccatatt acgtatatgg
    19501 cgctttaaat ttgcaaaacc tactttcaaa gcatcaagat tctcattttt aagttcatct
    19561 tttttcattc cgccatgcat tttcaatgca cggacagtgg cgacaatcac cacagcatcc
    19621 ggcgcttttt tcaagttagg tactttgata tctaaaaatt tctctccgcc aagatctgca
    19681 ccaaatcctg cctctgtgac aacgtaatct gctaatctca atgctgtctt ggtagctaaa
    19741 atactattgc agccatgagc gatattggca aacggtcccc cgtggacaaa agctggtgtt
    19801 ccgtaaattg tttgtacaag attcggcttg attgcatctt tcagcagtaa tgccagagcg
    19861 ccttctgctt tcaagtctcc agcagtcaca ggctgacggt caaatgtata gccgacaacg
    19921 atccttgcaa gacgagcctt taaatcttca aggtctgccg caagacacaa gatagccatg
    19981 atttcgctgg caactgtgat atcaaaccca tcttctcttg gaacaccttg gattggccca
    20041 cccaagccaa caattacttt acgcagttca cgatcattga gatcgactac ccgtttccaa
    20101 atcactcggc gggcatcgat gttcaattca tttccttgat gaatatgatt atctaaaaga
    20161 gcagataatg cattattagc tgttgtgata gcatgcatgt caccagtaaa atgcaagttg
    20221 atatcttcca taggcaatac ctgtgcatat cctccgcctg cagcaccacc tttgattccc
    20281 atcacaggac caagtgaggg ttctcgcaat gcaataacag attttttatt gattttattg
    20341 agcgcgtctc ctaaccctac agtgatcgtt gactttcctt cgccagctgg tgttggattg
    20401 atggaagtaa ctaagatcaa atgcccctca gcgttatcct ttgatcgatt gattccagaa
    20461 aaattgattt tcgccttata tttcccatac agttccaaat cgtcttcctt aagatctaat
    20521 ttactagcca cttcaacaat cggttctagc tctgtttctt gtgaaatttg cagatcattc
    20581 ttcatttgat tacccctttt cacgaacttt attcaacaaa atatcttctt tgttaagata
    20641 tgccaattat accttttttt attcagaaaa aaaacataaa attacaggtt tttaatttat
    20701 ttgacgtact tataaatact ctttataatg aaggctatga tcagacttta gaaaggtcgt
    20761 gagtgctttg accacaggaa ttgtaaaatg gtttgacaac aaaaaaggat acggctttat
    20821 cagttatgat gacacagaag aaatttttgt acattttact gcgattgaag aagagggatt
    20881 caaaactttg gaagaaaatc aagtggtcga atttgagatc atcgaaggga atcgaggaac
    20941 acaagctgcc catgtcaaga aaggcaacgt tcagactacc gatactagta tgcatgaata
    21001 gataaacaaa tagagtgaga cgctaaacgg gatgaaccgt acgtctcact cttttctttt
    21061 cctgtaaaaa ttcgtttttt taggttctga tttttaaaat tagctttttc tttttttcgt
    21121 ataaggataa ggaattgatt ctgatttggg tccgtttttt tcaaaatgat caaaaaggac
    21181 tacttgatct ttttttcgca tcatgaaaac agatggggct ttctcatctt gcaacatcat
    21241 ttgcacccca gtattagttg gcgtcaaaga tcgaatctgt ccgacagata tttctcggtc
    21301 tttccaaaaa gcagcataac gtataatcac agagtttgat tttaaaataa aagaacgccg
    21361 caaacctaga aatagaaaaa caagaaaaat acctaaaaca aaattgcttt tccaataagg
    21421 acctgtgttt tctaaagaaa gaatcagact aaaaaacaga atgatcaagg tcaatgacca
    21481 atagatgatc gtatgtgcca gttcaggctg ccatcgaata ttttttttca ttctctaacc
    21541 tctcaccgat tcagtaatga tataatctta ccataacatt agtttgaaca aaaaggagaa
    21601 tctcttttta tgttaaaagt atacattgat gcctctacaa aaggcaaccc tggtcctagt
    21661 ggaggtggaa tcttgattgt ctatcaaggt aaacaagaac agctatctat cccgctttct
    21721 atagggacaa accatcaagc agagttcgaa gtctttttaa aaactttaga atttctaaag
    21781 aaaaacgact tacagaatga aacgattttc tgtttttcag acagcaaaac actagtttct
    21841 acggtcgaca aaaacgcaac gaagaacgag ctcttccttc cctaccttca aagaatccaa
    21901 gaacttctat ccgaattttc tttattgatc ctgcaatggt tgcccgaaaa caaaaataaa
    21961 ggagcagata atcttgcacg tcaggctctc cataaacaat taaaagaaaa aaagactctt
    22021 taaattaaaa actttaagga gtctttttat agtttctcat ttaatataaa agataattgt
    22081 gatcaaacgt aatttccaat tggtaatctc cgattttttc ttctatttga ctacgtaaga
    22141 ttctttctag ttctgtatca acaaactgga atttctcagg gaccactaca tcaaattgca
    22201 gcgtttttcc ttgatgaatt actctaaaat catgaatatt aagccctgta cctgtttcaa
    22261 gaagaatttg ctttaactgc cgcaagatat tatagtattt ttcgttatca acaggcattg
    22321 gatccaagtg acagacaagt tccacatcca aagacttttt aaagtctttt tctatcagat
    22381 caataatctt atgagccaca ttcaaattca ttgattcatc tacttcgatg tggactgatg
    22441 caaagcgttt attgggtcca tagttatgca ccaataaatc atgatagcca agtatatcat
    22501 cgcaagcatt taaatgctct tccatttctt caatctctgc tggcgttggg cgacttccta
    22561 atagttcgta tacaaaattt cgaagcatcg tcaatccact ataaaggata tataatgcta
    22621 aagcaaaacc tatatatcca tcaatacgcc atccagttac ccattcgatt gctgctgaaa
    22681 gcaatacagc cagtgtagta aagacatcat tataactatc tgttgctgta gctctcaatg
    22741 tttcagaatc aatggattgc gcaataacct gatacatttt gccttgtgca aatttcaaaa
    22801 agatggaaat gattaggaca aaaaagacga tgggtgttaa agagacattt tctggatgga
    22861 tgattttttc agcagaagac tctaaaaatt gaaatcctac ataagtaatg atgatcgaaa
    22921 caaataaccc actgatatat tcgaagcgtt cgtgtccata aggatgttcc tgatctgctg
    22981 gctttgcagc aattttaaat ccgatcaaag tcaatatgga tgaagcagta tctgatagac
    23041 tgttcactgc atcagccata atggagacac ttcctgaaaa aagcccgatc attagcttag
    23101 agacaaacaa gatcagattc gtaaccaatc ctaagatacc cgctagtact cctttttttg
    23161 tccgctgttg cggtatttgt ttcttttttt cttcttgttt cttagccaag ttttttaccc
    23221 cttctagttt gcttgttgct caggtaaaaa gatggagagg acgattgttt tcctctcctc
    23281 tcttcctttt tctatctatc gtgcgtccta ttactattaa aagatggtca ttattctggt
    23341 ttcaacggtg ttgctgcaaa taacgctttt gctagtaatg gtgttatgat tcccgcacct
    23401 attgcttctg gtatcccatt gattgctgca acccctgcta aggttttaaa taaaagagca
    23461 gagtctacac cataggcatc tgccgttgca cctgtataaa ataatcccat gaatcctaac
    23521 actaagactg tattgaccaa tgaacccagt acccctgcaa aggctgagct gatcgttatt
    23581 gatttatttt tttgataaat ccagtggaaa accaagcctg ctactaagcc aacaagtact
    23641 ctgggaacta ccgagataat cggattcgtg aacactaatg tatcaaatgg cgttgttggc
    23701 atggcatagg cacgaacaat tgtagcgatt ccccaaaaca agccaatcac catgccatct
    23761 tttgggccta atactactgc agcaataatt actgtgatat ggataattgt taaactaatg
    23821 aatcctaatg gaataaaccc cagccaagga accatcgctt gtacgatgat gattgctaac
    23881 aagatcgcac gtaagactag tcgaaaggtc ttatttctac tattcatttt ttcacccctt
    23941 tttatttata ctaatcgtaa aaatttctgt cactttcgtc aactaaagac catccgaatc
    24001 cgaccatttg attagatgcg ccatccaatt gaaaaaagta tgagggcaag acttgtttgt
    24061 cttcgccccc ataatcatgt ttcgttcaat gtttgaactt ttgtttttct gtcaaacgta
    24121 aacgccctat tgttgcgcaa cccattcttt cgcagcttta agtgcatctg gaataccagc
    24181 aggatttttc ccgccagctt gtgccatgtc tggacgtcca ccaccgccac cgcctacttt
    24241 cggtgcgatt gctttaatca agtcgccagc ttttagtcca gcttcatttg attctttcgt
    24301 cattgccgct agcagactga cttttccttc ttgttcgttt gctaaaacaa gaatatctga
    24361 aatatttttt tgtttccatt ggtcagctaa ttgacgcagc tgattcatat ctttcacttt
    24421 tacttgtgct gcaatgattg tttttccatt gatcgtttct ggatctttga atacatcacc
    24481 agcttgttga ttcgctaact tgctagctaa ttgttcattt tccttttgta gctctcttac
    24541 ttgctgttgc aattgttccg cttttgaaac aacttctttc aattgaggtg atttaacaat
    24601 tgttgctact tgttttagtt gtttttcttc ttcttcaagt agttcgtacg cttctttact
    24661 tgttacagcc tcgattcgtc gcacgcctgc accaattcct gattcagaaa cgattttgaa
    24721 gattccgatg ttttctgtat ttgctacatg tgtgcctccg cacagttcga ttgaccagcc
    24781 gccaatattt actactcgaa cgtcatgtcc gtatttttca ccaaacaaag ccattgcacc
    24841 catgtttttg gctgtatcga tatctgtttc aattgtttca actgggatag cttcccagat
    24901 tttttcgttg acgattcttt ccatttcagc taattcatct gaagtgattt gaccaaagtg
    24961 ggtaaagtcg aatcgtaaat gtccaggagc gactaaagaa ccagcttgat ttgcatgctc
    25021 gccaagtact tctttcaatg ccttgtgcag tagatgggtt gctgtatggt ttttgatgat
    25081 ccgattgcgc atcgattgat cgatcaatag atgataggtt tgtccttcac tcattggtgc
    25141 ttttacttct acggtgtgca taaattgacc attaggcgct ttttgaacat ctgtaacaac
    25201 tgctacgatt tcgcctactt cattcatgat ccatccttga tccgctactt gcccacccat
    25261 ttctgcatag aaaggtgttt gatcaaagat catttgagct tcaccttctg cgacttcatt
    25321 caaaagagac tcacctttaa cgatgaccaa taattgacta tctgattctt gttctgtgta
    25381 tccaatgaat ttactttcta ctttgatatc tgtcaataaa gcagattgta cccccattga
    25441 tttttcagta ctgcgggcag agcgagcacg ttcgcgttgt gcatccattt ctttttcaaa
    25501 accagcatga tcaactttca gtccttcatc ttctgccacc tcttccgtta attctaccgg
    25561 gaagccatat gtgtcgtata gtttgaagat gtcttttcct gctagagtcg tcccgttttc
    25621 gttttttact tcttggatca cttgatttaa gatttccaaa ccttcattga ttgtttcatt
    25681 gaaacgttct tcttctgtac ggataacttt ttcaataaat tctttttgtt gaagtacttc
    25741 aggataataa cttaccatga tttccccaac aacagggact aaacgatata agaatgcttg
    25801 ttcaatacct aattttttcc catgcatgac agcacgacga agcaaacggc gtaagacata
    25861 ccctctccct tcattcgatg gcaatgcacc gtcgccaata gcaaatgaaa gggcgcgaat
    25921 atgatctgcg attactttgt aagaaatatc tgttactggg ttttcaccat attttacttg
    25981 tttgcttagc ttttctacgg cgtggataat aggcataaac aagtctgtct caaagttcgt
    26041 tgacgcatct tgaacgattg agaccatgcg ttccaatccc atccccgtat caatgttttt
    26101 atgaggaagt ggttcaaatg tgttatcagg cttatggttg aattctgaaa atactaagtt
    26161 ccagatttct aaataacgtt cattttctcc tcctggatag ttttcaggat cgtcttctgc
    26221 taaatcgtta taagcttctc cacggtcata gaaaatttcc gtatccggac cacatgggcc
    26281 tgcaccgata tcccagaagt tgtcttctac atcaataatg tgatctagtg gcaggccaac
    26341 ttcttcatgc cagatgcgtt ttgcttctgt atcttttgga taaactgtta cataaagttt
    26401 ttctggatcg aatgccatcc attttggatc agtcaaaaat tcccatgccc agtggatggc
    26461 ttcatttttg aaatagtcac caatcgaaaa attacccagc atctcaaaca tcgtatggtg
    26521 ccgtgctgtt ttaccgacat tttcgatatc atttgttcga atagattttt gggcatttgt
    26581 gattcttgga ttttctggca caactgaacc atcaaaatat tttttcaatg ttgcaacacc
    26641 agagttgatc cacaataagg ttggatcgtt cacggggatc aaagacgcac taggttcaat
    26701 cgtatgtcct ttagattgga agaaatcaag aaacatttgt cgaacttgtg cactacttaa
    26761 ttgtttcatg tcattacctg ctttctataa attaaataca aaaaaacacc atcacagcca
    26821 aggacgaaaa ctcgcggtac caccttgatt gcaatgatgt gtaatcatta cctcttaaac
    26881 tcgataacgc tgagctgcgt cggtatttct accaaaatag aaaaagggag caatttgatt
    26941 agtgactatt cttttttcag ccaagaaaga attttctgtg agtcttaaaa aacaaatcat
    27001 atccttttcg tacttaatta gtatacgcat tctattgatc actgtcaata tctcaatttt
    27061 tattttcatt tccttttggt catactccac gatttttggt acgataagaa taaaggaatc
    27121 aatacatctc tgctattcat gacaaggagg aatatgatga aaaaaatagt tggagcggat
    27181 gaatggatac gcgcagctag ctgctttttg agatatcaag tttttgtatt agaacaaggg
    27241 attcctgcag aactagaatt cgacggaaaa gatatcccgc aacaaaccta ttatctattt
    27301 cttgatcaaa aaagaccagt agctactttg cgttatgaaa agaaaacacc tacttgcttc
    27361 aagccggaac gattttgcgt agcaaaagaa taccgaggaa aagggttagg cggtcagttg
    27421 cttgaagctg ctgaaaaacg ggcggtttca gaaggttgtc agactagtta tgtagtagct
    27481 gaaatgacgg ctgtagattt ttatgaaaaa caagggtatc atacttgcac agaacctttt
    27541 attgaagatg aagtactttg tatcggaatg aaaaaaagtc tagcttaaaa acaagagatt
    27601 gtgacacgcc ttttgtcaca acctcttgtt ttttatttat gtgaattttt cttattttta
    27661 cgagcagtac ggctttgctg tctgcgttcg attttgcgtt cttttttatt tttttctgca
    27721 attgcccaat cgattttttt cttataacca ggcttgatct ttttcttttt cttcttcaca
    27781 agaccaatca gcgtgggatc taatacatct tttgattttt ctcgtttggc acgtctatta
    27841 cgatcgtatg ttttgacgat ttccccgttt ttgatttctt ttggttcaaa tgagacgccc
    27901 aatttttcta tcgcatcaat ggcttgctca tcatttggcg aatataacgt aatggccgtt
    27961 ccttttaagc cattacgtcc agtacgtccg acacgatgga taaagaagtc tagatcttct
    28021 ggaatttctg cattaataac atgagagaca ccttcgatat cgatccctct agcagctaaa
    28081 tcagtcgcta caacatattg atactccaga ttctgtactt gtcgcatcac tcgttttctc
    28141 tctcttgggg tgatgtctcc atgaatcttt gctactttca agccttggtt tttcaagtaa
    28201 tcggcaattt catccacatg ctgttttgta ttggcaaata cgattgctaa ataaggatga
    28261 ccaattgtca gcagttgata aatcatttga ttctcatctt taccttttgt tgaaatcagc
    28321 caattttcaa tgtcttcaga aataactgct tttggtttga tttcttcaat gattggattt
    28381 tccatgtatt ttcgtaagaa tggacgaagt ttttctggaa tagtggcaga aaaaactaaa
    28441 aactgcagct tttctggtaa tcgacttgca atttggtcta cttcatttaa aaaacccata
    28501 tccaatgtca tatccgcttc atcgacaaca aatgcaaatg cggtgtgaat cttcagcgct
    28561 tgttcattca tcatgtctaa tattctacca ggcgtgccta ctacaacctg tggctgttgg
    28621 tgatgcagac gatttaattg acgctgtttg tctgtaccgc cgacaaaatt cgagacacgg
    28681 atctccggtg tagaaaattt agcgatttgt gtagctgctt catagatctg tgcagctagt
    28741 tccctacttg gagctgtaat aacaacttgt acttcctctt tttctgcatt gattttttca
    28801 aacaaaggca acaaaaacgt atgtgttttt cctgtaccag tttgagattg cccaatgata
    28861 ttttttcctt ttgcaattaa aggaatcaaa cgttcctgga cctctgtggg ctgtttgaag
    28921 ccctttgcgg ttaacgcttc attgataaac ggtttgaagc ggaatatatc aaaattattc
    28981 attcgtgcac ctcttctctt taaattatca cgactttggc attataacac agacaaagcg
    29041 tttttgctca gctaatttcg agaatcatca tcctttgttt ggccaatcgt gctaacagta
    29101 tatgtgtgac tagctttttc ataaaacaga atccgttttt ttctcaaaaa tgatagcaag
    29161 atatttaaaa taaaaatacc ttgtagtaac aagacaccga gagaaatgaa tactgcactc
    29221 atctgcaaca ccgtattcgt tgtcgaattc atgatttgct gaagcaactg ccccaaccag
    29281 cttaaaccat aaaaaagaaa gtacagatac ccgtagcgga tcatcaatgc ttttaaagaa
    29341 attcgttcgc ggtcttcttc caccaaacgg atacgcacaa tttttttgcc aagtgtccat
    29401 ccattggtta taaacggtac aatcataaag tataccccta cttctaataa aagccaccag
    29461 atatgagaag taactgcccc tgaatcgaac gcaattttaa agaaaatcgc cgctaccaaa
    29521 ttaataagag ataaaaatgt ccagtcgatc aaataagcga ccaagcgtcg agtcaatgag
    29581 acagtctttc ctttttcata agaaagttca tccattcgtc ttcttgtagg aagcataaat
    29641 gtaaataacg gcgtaacgac aaaaccaatg attccaccca atgtatttgt cactaaatca
    29701 ttcacatcaa ataagcggta tggtcttggg tagataaaat aaagtccact tagctgcgtc
    29761 aattcaaaaa atagagaaag gcagaaacta gcaatcatcg ttttcataaa agaaagccgg
    29821 aaataatatc ttaaataaat gccaaacggt atgagtaata aaacattaaa agctggttcc
    29881 aaaaatacac tctgcttcat tgccggcagg taggtactag gttcagacaa gaccaatacc
    29941 gtgttgtctc tgaaatgttg ccatgaagca aataaatgca gctccatctt tggccctgtc
    30001 atttgggcaa ccgtctcctt tgccggaagt ggtaagatca ccaaaaaata cgcacacaat
    30061 aaataaaaaa cgaaagaata caaaataact gcccttgtta ctagaaatgt tccatacttt
    30121 cgatattcat aaataaaaaa aacagatgag atcgctaagg ctaaaaatgg aaaaacaatc
    30181 agcgcaaaac gaatcggttc gatataactt gccatatgac tcctccttga ttctttgtat
    30241 ctctcttatc ttagcagtcc tttgctgttt caagcaagta acgaggctat tatttctcat
    30301 ttctttcaaa gtaaagtaag ataaacacaa agggggtgtc gagatgctga atatgtactt
    30361 tgtttttggc gtacctattt ttttactgtt cctttatgct acgatcgctt atgtaagaaa
    30421 aagaactaca attcattatt taggatttat tctcctgatt atttcgggtt tcatgctagt
    30481 cttcaatctt cagacttggc agcaagcact tcttgaaatg gataaaatga ctccacatgc
    30541 tttgtctaaa gtgcttggct accctgtcta tctgatttgg cttcccattt tcatttctgg
    30601 ttgcttggtt ttattaaata tttatcgcgg cgtacgccga atagttcagt tacgcaaatc
    30661 aaagtaaaag acagaaatcg gttgagcccg atttctgtct tttactttgc tatttcatcg
    30721 tagacaaaac gacatttacg tgatcaaaat taacgagtac ttttgacatt tcttccacgt
    30781 actcctcatt taaataaaat attttgtttg gcagagaagt gcagttctaa taaaattcga
    30841 atgttttagc tatctacgtt ttaaatagag ataaatcggg ataccagcaa gtgtcaatac
    30901 tatccccatc gaagctaaaa aggtctgagt gataagcgtg cttgatacga taaaagtccc
    30961 tccaatgatt gctactagtg gaataaacgg atacattgga actttgtatg gtcgaaacaa
    31021 atcaggttct tttttacgaa gaagaatgac accaacaaag accatcgtat aaaaaatcca
    31081 aatgacaaag atcagcatat ccgttagtgt atcaaaacca ccgatcatca tcatgccaat
    31141 agcgatgact agctctaaga tacctgcggc tacaggaact ttagttttat catgaagttt
    31201 agcaaagagc ttgctaaaag gcaggttgtt ttcttttgcc ataacataag ggagacgcat
    31261 tccagtaagg gtatagccat tgatggttcc ataaacagaa atcaagatac caactgtgac
    31321 cagtcttcca ccgaagccgc caaaaatcat ttttgcaacg tcacttgccg cattgctgtt
    31381 tcctgcgact ccgtcgatag atgcggttct taagaacacc gcatttacta ataaataaac
    31441 gatcatgatt ccgatgattc ctaaagaaat tgcttttggc aaatctttcg ccggcttttt
    31501 caattctccc gaaatatttc ctacgtgtat ccaaccgtcg tatgcgaaca tcgttgctag
    31561 caagcccgct cccaaggctg agaaaaatga aagattttct cctgcttgga tcggaaacag
    31621 ttggaagtct actccttctt gtcggaacaa accgaaaatg acgatcacaa acaaaggaat
    31681 aagcttgcag acaagcgtaa tcgactgaaa agcccctcca gctttagaac ctaaaaaatt
    31741 gatcaacagg atcgatacag cagctgtaac agctacggga acaatcattg actgggaaag
    31801 accaaataga ttgacgaact gtgtaccgaa aatgatcgac aaggctgcta catttgctgg
    31861 aaaataaatc acgacttgcg cccagcccaa taaaaaagct gctgtatttc cgtaaatccg
    31921 ttcgatatat ttaatcatcc ctcctgtttc tggaatagca gctgccagtt cagctcctgt
    31981 tagtcctgca cagacagaaa tcataccacc gagaaaccaa gaaaacatat gcaaactggc
    32041 ggatcctgta acttctgcta cgcttgcggc tttaaaaaat acccctgcac cgatcactgt
    32101 gcccataaca gtcgataaag cagtaaaaaa tcccatcgta cgttttaatt cattttctat
    32161 ttttacttct tttactggcg tggcttgata ttcttccatc ccttgtcccc tttcatacca
    32221 tagccaatcc caaaagtata aaaaactttt tggatgtggt tcttgtttta taccgtctct
    32281 accaattttt ctttcagttt ttccaacata tcctttgtca tcacatctaa gtcgtatttc
    32341 ggcgaaaagc cccattcctc ttgcgcacaa gaaacatcta gtgaatttgg ccaagattct
    32401 gctattgact gacgtacagg atccacatca taatccattt caaaatctgg tatgattttt
    32461 tgaatagatg ctttgatctc ttccgggtca aaagacatcg ccgatatatt gaaggcattt
    32521 cgatgaacca atcgatcagg atctgcattc atgagtttta taatggcatc gatcgcatct
    32581 ggcatataca tcatatccat tgatgtacct tgatcaatga aactagtgta ctttccttct
    32641 ttgattgctg aataataaat atcgactgcg tagtctgtcg taccgcctcc tggcaaggtt
    32701 gcataagaaa tcaatccagg gaaacggaca ccacgagtat ctacgccata tttcacataa
    32761 taataatcac atagtagttc tccagctacc ttcgttaccc catacatggt tgtaggacgc
    32821 tgaagagtat cttgtggggt atgatctttt ggagtatttg gaccaaacgc gccgattgaa
    32881 cttggcgtaa aaaatttcag ctggaattct ctagcgactt ccaatgcatt gaccagccca
    32941 gtcacgttca aattccaggc taattgtggt tttgcttctg caacagctga caaaagagca
    33001 gccaaatgaa tcaatgtgtc cacttgatat tgttctgcta tgctgcgcat tttttcgtaa
    33061 tccattacat ctaggatctc aaagatatcg tttttctcaa tgacttcagg catgcgtata
    33121 tctgtcgcaa tgacattttc actgcctagt tcttgacgta gccgtgtgat caactctgaa
    33181 ccaatttgtc ctaaacatcc tgtcaccaat acttttttca tgatgatcct ccctgatctt
    33241 ttttactact atcttcagat gattaacaat atatgcgtga acatgttctc taattttaaa
    33301 tagacgaaaa aactaaattt agttaaataa tttccatttc ttttcctatt ttttgataaa
    33361 ctgctactgc ttcatcaagc atttccctcg tatgttccgc agtcggcata tttctgatcc
    33421 tgcctgtccc aagaggcaca gttggataaa cgattggttt agcataaatc ccatgttcga
    33481 tcagcttctt agagaaagtc tgagtcactt tttcgtctcc caaaatgact ggagtaatag
    33541 gtgtttcaga cataccgatg ttatagccta cttttttcaa ttcttcttta aaataattag
    33601 cattttccca aactttttcg acaagttccg gatgttcttg catcaaagta atcgaagcca
    33661 atgcagctgc agctgcacct ggagttagcg aagtagaaaa taggaatggc cgacttctag
    33721 ctttcaacca gtcgattagt gttttcgatc cagctacata acccccaaca acacctatag
    33781 ctttcgataa cgtgcccatt tgcatatcga ttttgtcgct taatccaaaa tgcttgacgg
    33841 ttcctgcacc ttttccagtt acgcctgagc cgtgcgcatc atcgacgtag gtgatcagtc
    33901 catatttttc aacaatcgga ataatttccg gcaatcgtgc aatgtctcca tccatggaga
    33961 aaacaccatc tgtgatatac atgatttttt tatatttctt actttctatc gcttcctttg
    34021 cttttttctc aaggtctttc atatcttgat gtttaattcg gatgattttt gctccggata
    34081 agcggcaacc gtcaataata gatgcatggt ttaattcatc cgataagata gcatcttctt
    34141 ttgtcattac tgcagagata gcgcccatat tgcagttgaa tccagattga aaggcgattg
    34201 ctgcttctgt ccctttgaat tctgcgattt tttcttctaa ttgctgatgg attttcagcg
    34261 aaccattgat cgttcggact gctcctgctc ctacaccata agtttcggtt gcttcaatac
    34321 atgctttttt caattcttcg cgattggcaa atccaagata attgttggat gctagattga
    34381 tcatcttttt tccgtctacg atgatacaag caccattttc actttctagt atgtcgatcg
    34441 tattgtataa ccccttttct ttcagttgat ccaattcttt ctctaaatac attgttagtt
    34501 ctttggaaga cattgtctcc acctccatat tcatctgtct tgcagaacat accaaacata
    34561 tatcgtgtca ttcatctaca aagcaagtat gctatatttt tgataacgct tacactgatt
    34621 atgagaatta tttaaccaca ttttttattt acagtatctt tttactttca aatgacttat
    34681 atagtatgaa caattacctt ttagataatg atctatttta ctctacctgg gcagataaat
    34741 acaacacaac cattgataga agccctttcg ttaaaatcaa ttgtattctg aatatttaat
    34801 ttatttattg catagaccaa taaaaataca taaaatttcc atcttcgttt atcagcaatt
    34861 tttaatttta ctctctgaat atttcttaaa agttttactt gttgaattcg aaaaaaggac
    34921 tgtgacaaaa gtcttgtcac agtcctattc ttcc
//
LOCUS       DADGHT010000020        34898 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.020, whole genome shotgun sequence.
ACCESSION   DADGHT010000020 DADGHT010000000
VERSION     DADGHT010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34898
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.020"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(59..187)
                     /locus_tag="JX887_000849"
     CDS             complement(59..187)
                     /locus_tag="JX887_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAX1256857.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="JX887_000850"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="JX887_000850"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAX1256858.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="JX887_000851"
     CDS             complement(1674..2729)
                     /locus_tag="JX887_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAX1256859.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="JX887_000852"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="JX887_000852"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAX1256860.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="JX887_000853"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="JX887_000853"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAX1256861.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="JX887_000854"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="JX887_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAX1256862.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="JX887_000855"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="JX887_000855"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAX1256863.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="JX887_000856"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="JX887_000856"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAX1256864.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="JX887_000857"
     CDS             10491..12050
                     /locus_tag="JX887_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAX1256865.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="JX887_000858"
     CDS             complement(12161..14092)
                     /locus_tag="JX887_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAX1256866.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="JX887_000859"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="JX887_000859"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAX1256867.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="JX887_000860"
     CDS             complement(15021..15773)
                     /locus_tag="JX887_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAX1256868.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="JX887_000861"
     CDS             complement(15932..16141)
                     /locus_tag="JX887_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256869.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="JX887_000862"
     CDS             complement(16152..17480)
                     /locus_tag="JX887_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256870.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            complement(17845..18432)
                     /locus_tag="JX887_000863"
     CDS             complement(17845..18432)
                     /locus_tag="JX887_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAX1256871.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="JX887_000864"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="JX887_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAX1256872.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="JX887_000865"
     CDS             complement(20012..21301)
                     /locus_tag="JX887_000865"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAX1256873.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="JX887_000866"
     CDS             complement(21455..22387)
                     /locus_tag="JX887_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256874.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="JX887_000867"
     CDS             complement(22544..23203)
                     /locus_tag="JX887_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAX1256875.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="JX887_000868"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="JX887_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAX1256876.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGASGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="JX887_000869"
     CDS             complement(24244..24534)
                     /locus_tag="JX887_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256877.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="JX887_000870"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="JX887_000870"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAX1256878.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="JX887_000871"
     CDS             complement(26821..28176)
                     /locus_tag="JX887_000871"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAX1256879.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="JX887_000872"
     CDS             complement(28200..29369)
                     /locus_tag="JX887_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256880.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="JX887_000873"
     CDS             complement(29366..30253)
                     /locus_tag="JX887_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAX1256881.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="JX887_000874"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="JX887_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAX1256882.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="JX887_000875"
     CDS             34320..34841
                     /locus_tag="JX887_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAX1256883.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT         9423 a         7579 c         6267 g        11629 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagcc cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacac
//
LOCUS       DADGHT010000021        34437 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.021, whole genome shotgun sequence.
ACCESSION   DADGHT010000021 DADGHT010000000
VERSION     DADGHT010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.021"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..650)
                     /locus_tag="JX887_000876"
     CDS             complement(<1..650)
                     /locus_tag="JX887_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAX1256884.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPL"
     gene            complement(874..2814)
                     /gene="thrS"
                     /locus_tag="JX887_000877"
     CDS             complement(874..2814)
                     /gene="thrS"
                     /locus_tag="JX887_000877"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAX1256885.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3151..3330)
                     /locus_tag="JX887_000878"
     CDS             complement(3151..3330)
                     /locus_tag="JX887_000878"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAX1256886.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3377..5200)
                     /gene="cadA"
                     /locus_tag="JX887_000879"
     CDS             complement(3377..5200)
                     /gene="cadA"
                     /locus_tag="JX887_000879"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAX1256887.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5478..7757
                     /locus_tag="JX887_000880"
     CDS             5478..7757
                     /locus_tag="JX887_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1256888.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(7850..8497)
                     /locus_tag="JX887_000881"
     CDS             complement(7850..8497)
                     /locus_tag="JX887_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256889.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8676..9395)
                     /locus_tag="JX887_000882"
     CDS             complement(8676..9395)
                     /locus_tag="JX887_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAX1256890.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9526..10677)
                     /locus_tag="JX887_000883"
     CDS             complement(9526..10677)
                     /locus_tag="JX887_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAX1256891.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(10894..11634)
                     /locus_tag="JX887_000884"
     CDS             complement(10894..11634)
                     /locus_tag="JX887_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1256892.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11638..11961)
                     /gene="rsfS"
                     /locus_tag="JX887_000885"
     CDS             complement(11638..11961)
                     /gene="rsfS"
                     /locus_tag="JX887_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAX1256893.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12018..12611)
                     /locus_tag="JX887_000886"
     CDS             complement(12018..12611)
                     /locus_tag="JX887_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAX1256894.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12595..13242)
                     /locus_tag="JX887_000887"
     CDS             complement(12595..13242)
                     /locus_tag="JX887_000887"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAX1256895.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13255..13566)
                     /gene="yhbY"
                     /locus_tag="JX887_000888"
     CDS             complement(13255..13566)
                     /gene="yhbY"
                     /locus_tag="JX887_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAX1256896.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13582..14691)
                     /gene="yqeH"
                     /locus_tag="JX887_000889"
     CDS             complement(13582..14691)
                     /gene="yqeH"
                     /locus_tag="JX887_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAX1256897.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14688..15215)
                     /locus_tag="JX887_000890"
     CDS             complement(14688..15215)
                     /locus_tag="JX887_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAX1256898.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15395..16180)
                     /locus_tag="JX887_000891"
     CDS             complement(15395..16180)
                     /locus_tag="JX887_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAX1256899.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16173..17042)
                     /locus_tag="JX887_000892"
     CDS             complement(16173..17042)
                     /locus_tag="JX887_000892"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAX1256900.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17043..18422)
                     /locus_tag="JX887_000893"
     CDS             complement(17043..18422)
                     /locus_tag="JX887_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAX1256901.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18430..18849)
                     /gene="fabZ"
                     /locus_tag="JX887_000894"
     CDS             complement(18430..18849)
                     /gene="fabZ"
                     /locus_tag="JX887_000894"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAX1256902.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(18874..19350)
                     /gene="accB"
                     /locus_tag="JX887_000895"
     CDS             complement(18874..19350)
                     /gene="accB"
                     /locus_tag="JX887_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAX1256903.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19353..20588)
                     /gene="fabF"
                     /locus_tag="JX887_000896"
     CDS             complement(19353..20588)
                     /gene="fabF"
                     /locus_tag="JX887_000896"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAX1256904.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20607..21344)
                     /gene="fabG"
                     /locus_tag="JX887_000897"
     CDS             complement(20607..21344)
                     /gene="fabG"
                     /locus_tag="JX887_000897"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAX1256905.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21356..22273)
                     /gene="fabD"
                     /locus_tag="JX887_000898"
     CDS             complement(21356..22273)
                     /gene="fabD"
                     /locus_tag="JX887_000898"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAX1256906.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22380..22604)
                     /locus_tag="JX887_000899"
     CDS             complement(22380..22604)
                     /locus_tag="JX887_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAX1256907.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22657..23619)
                     /locus_tag="JX887_000900"
     CDS             complement(22657..23619)
                     /locus_tag="JX887_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAX1256908.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23629..24069)
                     /locus_tag="JX887_000901"
     CDS             complement(23629..24069)
                     /locus_tag="JX887_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAX1256909.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24375..25340
                     /locus_tag="JX887_000902"
     CDS             24375..25340
                     /locus_tag="JX887_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAX1256910.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25397..25627)
                     /locus_tag="JX887_000903"
     CDS             complement(25397..25627)
                     /locus_tag="JX887_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAX1256911.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(25713..26600)
                     /locus_tag="JX887_000904"
     CDS             complement(25713..26600)
                     /locus_tag="JX887_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAX1256912.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(26689..27912)
                     /locus_tag="JX887_000905"
     CDS             complement(26689..27912)
                     /locus_tag="JX887_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAX1256913.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(27929..29008)
                     /locus_tag="JX887_000906"
     CDS             complement(27929..29008)
                     /locus_tag="JX887_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAX1256914.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            complement(29139..30866)
                     /gene="ptsP"
                     /locus_tag="JX887_000907"
     CDS             complement(29139..30866)
                     /gene="ptsP"
                     /locus_tag="JX887_000907"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAX1256915.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(30866..31132)
                     /locus_tag="JX887_000908"
     CDS             complement(30866..31132)
                     /locus_tag="JX887_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAX1256916.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            31611..33845
                     /locus_tag="JX887_000909"
     CDS             31611..33845
                     /locus_tag="JX887_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAX1256917.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            33993..34313
                     /locus_tag="JX887_000910"
     CDS             33993..34313
                     /locus_tag="JX887_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAX1256918.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT         9733 a         7467 c         6013 g        11224 t
ORIGIN      
        1 ctaagcgggt tatttccaaa ttgcgtcaac gcaatgattt cgatattcat gcttttcgcc
       61 agctcggcta atgcgactac atctgcactt ctacctgagt ttgaaacaag ccaaagcact
      121 ttctttttct cattgctgac aagttgcggg agcaagacgt ggatatcttt ttcaaaaatg
      181 attggcttac cgacacgaga ccatttttgc agaatatctt ctactactaa agaagaggcg
      241 ccaaccccat ataaaaaaac agtctctgcc gattccaaac actctacgac tttttggatc
      301 gtttcttctt ctagaatatc tactgtttct tttatcgcta cttgtgcatt gttaccaagt
      361 ttgtttttga tagagtaaaa ggactcattt gcttctatat cactaaaacc ttcatcgatt
      421 ccagtctgta gttctgttga aatcgtgatt ttgaagtccg tcagactttg aaaaccgatt
      481 tttttggaaa aacgtacaac tgtcggcgca ctcaacccgg aagcttctgc taattcatta
      541 gctgtcattg tagggacctt ctcaatatta ccgataatgt agttggccaa ctttttttct
      601 gctgaagaat aatcttccat catactttca atacgactaa ttacgctcat aagttcctcc
      661 acccttttaa tgatagtcta tgtaagtata ccatatcaga cccttattca cggtcgtata
      721 ctggataaaa aacaaaaaaa caatccgccc aacagaatat cttatcccat caatcccaca
      781 gattctattg agcatctgtg tctttgagga atacctgtta tctattgttc ggattgcttt
      841 ctatctacta cttttttaca ggaaatttac ctattagttt tctctgctgt aatttttgac
      901 ttctgcttcc atagcatcaa taaagatatt caaatcttct acagctgttt ctttacttcc
      961 ataacgacgt acgttcactg ttgcatcttc caattccttg tctccaacaa ctaattggta
     1021 agggatcttt tgtgtttgag aggcacgtat cttatagccc attttttcat tacgatcatc
     1081 aacttctaca cgcaacccct tcatttgcaa acgttctttg atttcataag cataatcgcc
     1141 atgtgcatca acagaaacag ggatgattgt tgcttgtata ggtgccaacc atgttggaaa
     1201 agcgcctttg tatacttctg ttaaataagc gacaaaacgt tccattgtag aaacaattcc
     1261 gcggtggata actactggac gatgcgtatt ttccccgtct tctccaacat atgtcaaatc
     1321 aaagcgctct ggcaataaga agtctaattg tatagttgat aatgtttctt ctgtaccaag
     1381 agctgttttg acttgaacat ctagttttgg tccgtaaaag gctgcctcgc cttctgcttc
     1441 aaagtaatct agttctaatt catccatagc ggctttcagc attgcttggg ctttttccca
     1501 cattgcgtca tcatcaaaat atttatctgt attgtttgga tcgcgatagc tcaagcggaa
     1561 acgataatct gtaatattga agtcagcata tactgccacc atcaattcaa gcgtacgttt
     1621 aaattcatct ttgatttgat caggacgaac aaatgtatga ccatcattca acgtcatttc
     1681 tcgtacacgt tgtaaacctg acaaagcacc tgatttttca tagcgatgca tcattcctaa
     1741 ttcagcgata cgaattggta attcacgata agaatggatc gtgtttttgt agaccatcat
     1801 gtgatgaggg cagttcattg ggcgaagaac aagcatttcg ccatctccca tatccattgg
     1861 cgggaacatg tcttcttgat aatgatccca gtgtccagat gttttgtaca actcaacatc
     1921 tcccattatt ggtgtatata catgttggta acctagacta acttctttgt ctacgatata
     1981 acgttcgatc gtgcgtcgga ttgttgcccc ttttggaagc cagaatggca aaccagaacc
     2041 tacttctggg gaaaccatga acaagtcaag ttcttttcct agtttacgat ggtctctttc
     2101 ttttgcttct tcacggagac ggatatattc tttcaaagct ttcttgtcaa aaaaggctgt
     2161 cccgtataca cgttgcatca tttgattgtt tgagtttcca cgccaataag cacctgccac
     2221 tgataataat ttaaatactt gtatacggcc agtggatgga acatgtggtc cacgacacaa
     2281 atcgatgaat tcgccttgtt gataagcagt aatcacttct tcttctggca attcactaat
     2341 cagttctact ttgtacggat cacttgcaaa aatttctaat gcttcctgtt ttgaaagaac
     2401 acggcgttcg atcggcagat tttctttgac gattttcatc atttctgctt cgattgccgg
     2461 caaatcttct gcagttactt ggttttgtcc attatctgta tcgtagtaaa accctgaatc
     2521 gatagctggt ccaacgccaa agtggatatt tggatagagg cgacgcatgg cttgggccat
     2581 caaatgagct gctgaatgac ggactaagcc aagtgcatct tcatggtctg gtgtgatgat
     2641 ctcaatactt gcatcttcct cgattggacg agtcaaatca acgagttttc cgttcacttt
     2701 accagctaaa gctttttttg ctaagctttt tgaaatgctt tcagcaattg ccaatgttgt
     2761 tgttccagac tcaaattctt tgactgcacc atctggaaaa gtaattttta tcataatagt
     2821 ttcctccttg aaatgttttg attgatcaga tcatcaagct gaaaaacaaa aaaatcctag
     2881 catctcttga aaagagatac taggacgaaa agttcgtggt tccacctaat gttcaaacgc
     2941 aaatgcgttc ctcaagcgtt gtaacggtcc gaccgccctt gcttcaacaa gggtttcgaa
     3001 agtggtcatc ctttggtttt ctcctggaaa agtttcagcc tagcttttcc tctcttatcg
     3061 aagactctca aattcagttg gctttctcat caatcaatta tgtgtttatt taaccactaa
     3121 taaatagaaa aatcaagtgg gaaactaaac ttattttttc cattccccat ttacaccgta
     3181 tgttcctttt ttcatctcat tgatgatgac atggatgtgt tcttttggtg cctgcgtgtt
     3241 tttatgaaca gcttccgtga tatctttcat catattttct aattgttccg gactgcgacc
     3301 ttctactaat tcgacatgta cgaatggcat aatgctctct cctctttctg atcgttcttt
     3361 tttcaactcg attctatcat actatgtttg tcttgggtac tgaatcagga aaaatggctg
     3421 gatctttttt tgctctcaag gcactcaaaa tagagaccgt atccacgact tcttgcaaaa
     3481 cagctccgaa taatgcgggg attagtcccg tacttgcaat taacatcaaa aaaatacaaa
     3541 taaagatgcc aatcagtaca gactgtttcg ctattctcat cgtatctctt gaaatcacta
     3601 ctgcttttgc tacacgcaag agatcatctt tcaagatgac cgcatctgca ctttcactag
     3661 cagctgtaga accatgagcc cccattgcaa taccgatatc tgcagcagca agtgctggtg
     3721 cgtcattcac gccgtctcct accatcgcaa caggtctttg atctttaggg atactttcta
     3781 aaatggtcag tttatcttga ggcaagctac gggcatgtac agaatctaat tggacttttt
     3841 ctgcaatcgt ttgagcaatg gcagatccat ccccggtgat catcatcaaa tttttcacat
     3901 caagttttct tagctccttg attgtctttg ctgcttctgg gcgaatctga tccgaaaata
     3961 ggatcgttcc tgcaaaagat cgatcaattg ttacatagat tgctgtattg gacgtttcta
     4021 tttcttcagc tgaaacaaaa gaggcacgtc caatctttac ttcatgatta ttgactactg
     4081 cttggattcc ttgaccggtc acttctttca gttgactaac aggatacagt tggctgtttt
     4141 tcacgttgtt cactaacgaa cgagctaaga tatggctaga ttcctgttct gcactagctg
     4201 catacagaag tagctcttct ttttttattc cattgactgg ctgaatcgcc tctacttcca
     4261 atatcccttt ggtaagcgtt cctgttttat caaaagcaat cgtttttgta cgtgcgagct
     4321 tttcaatcgt tgttccagtt tttacaacga tcccgttttt acttgaacgg ctcattcctg
     4381 caactaaagc aatgggcgca gctagaatca gtggacaagg tgatgccact accagtacct
     4441 cagcaaatcg taaagggtct tttgagaacc accaagaaat accaccgatc aaataagcaa
     4501 tcaacgtgaa agggactgca taacgatcag ctaaacggac aaatcgggca ggcttttctt
     4561 ttgattcttc gactagttta ataatcattt gatactggct gtctgcggca cgtttttcag
     4621 cgatcatttg gatcgatccg tctccattta aagaccctga cataatctga tctccaggtt
     4681 tcttggtttc cgggcgggac tcacctgtca aagaagattc atcgaccgaa gattctcctt
     4741 tggtcactcg accatctgcg ggtacaagtt cgccaggctt gactagtaac tggtcatcaa
     4801 tatttatttc atcgattact atatcctgca attttccttc tttgaatcga tgggcaattc
     4861 ttggggtgtt atctaacaaa gactgcagtt ctttacccgc tcgtttattc gcgtaatcct
     4921 ctagactatc tccgcccgta agcatgatca atatcatcaa actagcccag tattctttga
     4981 cggctaatgt tgcaaggatt gcggtaatcg ctaatacatc tacgccatat cttcctgaac
     5041 gtaacgtctt gatcatttcc aaaaacatca agaaggcgag aatccctcca gtaaatgcga
     5101 caatcgcaaa tgcaagggcc ggctggtgaa aaacaaattc acttaataaa gctatcccac
     5161 caataagcaa agtaagtaaa aattttttga aatgtgtcat tgttttttct cctcttttat
     5221 gtgacttaga gaggttagta ataaatttcc agctgcctct ttcatcttaa gcatagtcct
     5281 tgactagcac tttttaaaac aataggcctt aattgaaaac aactatcact atcagcgttt
     5341 ccaaaattca tcagttctac aaacaaaaat attcagcaag gattactttt tcgattcatc
     5401 agttaaaaag tacctttttt cgaaaaacta tgctatactt ttaattcgtt atttacggcg
     5461 gaaggagcaa acatgcgatg aatgagaaac aactagaaca aacgcacgtg gatgaaacga
     5521 tcgaactaat ccagatcgaa caaaatatgc tggatacaaa acaacaagaa ttgactcagg
     5581 aaatgaatca ttcgacaaaa gacacagcta atcacaagat tcgagctggt tccaatgaag
     5641 ctttttatga atctgctgtt gaatatcgcc aacatgagca ggaattgctt ttgaaatacc
     5701 atactcttga agcacagcaa aaacgcctgc aaacgttgtc tgtcatgaaa gatagtcctt
     5761 attttgcccg tatcgacttt aaagaagacc gtgaaacaga aacattatat ctaggtatcg
     5821 cttctttaag agatctggca gaagaaacaa tcgttattga ctggcgcgca ccaattgcca
     5881 atctttatta tgaaggtgag attggtcccg cattttatga aactgaaaca gatagaatag
     5941 atgtcgatct gcagttgaaa cgacaattta aaatccaaga aggacgtatt ttatctatgg
     6001 tagatacgtc ggaagtaatc aatgatgact ttttgctaga gatattggat gaatcatcaa
     6061 gcaaccatat gaaaaacatc gtctctacga tacaaaaagc acaaaatgca atcattcggg
     6121 acacaacaag taaagtaatg ctgattgaag gaatcgccgg aagtggaaag acatccgctt
     6181 tgcttcaacg tattgctttt ctgttgtatc ataatcgcaa gtggctcgag gctgaaaacg
     6241 ttcttctatt ttcacccaac catttgtttt ctgattacat ctcgactgta ttgccttcat
     6301 taggtgaaag cggcgtgcct acacagacat tcaaaaatta tttggtgcag ctgctgccag
     6361 agttttcttt actagatgaa cagcaacaag aaagtggttt tttgctaggg gaaaaagatc
     6421 cgatacaagt gatgaaaagc ggattgacct tagtcgatca gattgatcgc tatatccaag
     6481 gcatcacaaa ctacggtccc ttgttccgtg atatgaaaat aaatggccgt acgatcctat
     6541 caaaggaatc gattcgccaa tggtataaag aaacaaatga acaattacct ttacatcata
     6601 gactttctct attacaaacg aagctcctga aaaaattagg cggtctgcaa aaagacgaaa
     6661 cacgtcagca atgggtcaaa gatctggcgg aagaacagct ccaagaacta tacgcaacag
     6721 atccaaatct tgaatataca gaacaaaagg agcgttcatt acgtaaaaaa ctggccaacc
     6781 aaatcgtacg taaaagattc cgtcgaatcc atcgagggat catgaattat caatttgtca
     6841 atataacgaa acaatatctc cactttctac aaactgtgcc actttctctt ctaacacgac
     6901 ataaaatcag cgagaccagg tggcaggaac atttgacaac tgttcgtaca cacttgcgtc
     6961 aaagagaatt gcgtcaagag gatgctgtac tattcttttt actgatgcgc cgaacatatc
     7021 cagtgacggt tacacacaaa gctcgctata tctttattga tgaaatgcag gatttcgcac
     7081 catcacaagt ggcattgctg caagccttgt tcccaaaagc aaatttgact ttctgtggag
     7141 atctaaatca aaatgtcttt ggaaatgaaa cgatcgttgg atcattggaa gaccttttcg
     7201 tggaccgtga agtcactcgt ttccaattaa cgacaagcta tcgctccaca aaagaaatca
     7261 ctgattttgc taatcatttt attgtgaaag aacatcaagt agaaacaaca gcaagaaaag
     7321 gagaccttcc tttgctcatc caaggaacaa cagatgatat caaattgaat tggttagcag
     7381 ataccattcg aacgactcag ggaaaagccc ggtattggcg tacagcaatc atagctaaaa
     7441 cacaagaaga atgcgaagct ctttatgctc aactgccaga cgagttgaaa caacaagtcc
     7501 agctgatttt aaatgagagt gactttatga agcgttccat tattttactt ccagcctttt
     7561 tagcaaaagg tctggagttt gaccgagttt tcttgtggga tgtagatgca gaacattttt
     7621 cttctcagca agacaaattg atcctttaca ccatgtgtac acgtgcgatg catgaattga
     7681 ccctttttac ctccaataat gaaagtcctt tgttaaacaa tatggatatt tcatcttatg
     7741 agaaaaaagt actgtaagta aaaagacaac tgctatcatt aatgttagca gttgtctttt
     7801 tatttacaat aataattgca gaaaaagtaa ttcaatcatt taaggtcatt tattctatat
     7861 ataaatccaa atctgtttca ggatatttta atttgacaag cgaaataatc attttcagtt
     7921 cttccatgtt ttctggatat tctgggtcaa ataccttgct atgacggcca atcccgccat
     7981 tgtcgatcaa tcggtaaatt cgattccatt caatgaattg gtcaattgat tggaaattgc
     8041 tgattggata gccgccacaa tccaaaatct ctgatacacg aaatgctagg tatgcactat
     8101 cgatcacttt attttttttc gtgtctatct tctcatttct ttcgataaga attttttcag
     8161 gacgatgttt caagctccac tctaatagta gaaagaaagc ctccatccga tactcttctt
     8221 caaataaccg aaaggctgaa tcagaacgac gaaaaagcag cggaatcaga taattttgtc
     8281 tataaatcag cattggtgcg cggtccacca tacactctaa ataacggttc agataccctg
     8341 taccgacata gtttcctaat cgatagcctt caacgccgaa tcttgcgtat ttttgcgcta
     8401 attttgaaca atcagttacg ttcacagcta actcttctac tttgcggtaa ccgcttaaga
     8461 tacgttcaaa aggttctaaa gtgatttttg cttccatatt cttccccgtc catcttccac
     8521 atacttcata tcatttcaca tgatacttat gctctcatca taccacaggt tgaattagaa
     8581 aagaaaataa atcacacaaa aaagcaagac aatctgttag tgagattgtc ttgcttttcg
     8641 aaaaagactg aatacttttc gttaaaactg gttgcttagt cttctaatgc cacattatgg
     8701 aacacatgct gtacatcttc tagatcttcc agtgcatcaa tcattttttc aaatgtttct
     8761 tgatcttctg gagatagtgt tacctcgttt tgagggatca tttggatctc agcgattgaa
     8821 aaatcagtga ttcctttttc ttttaatgct tcttgtatac tatggaaatc cgctacttca
     8881 ccgtaaacga tgatttgtcc ttcttcttcc attacatcgc gaacatcgat gtctttttcc
     8941 attaggtatt caaggatctc gtcagcgtct tctcctgcaa aagcaaagat tgctgtattg
     9001 tcaaacatgt aagaaaccgc tccggaaaca cccatgttcc cgccattttt cccaaatgct
     9061 gcccgtacgt ctgctgctgt tcgattcaca ttgttcgtca atgtatcaac aatcaccatt
     9121 gagccgcttg gtccaaatcc ttcatagcgc aattcagagt atgtttcatc tcctgcacct
     9181 tttgcttttt cgattgctcg gtcaataata tgttttggta cattataagt tttagcgcga
     9241 tcaatgacga aacgtagttt ttggtttgca tgcggatcag gatcacctga ttttgctgcc
     9301 gcgtagattt caatcccaaa ttttgcataa atccggctat tattagcatc tttagcagtt
     9361 ttctttgcta cgatatttgc ccatttacgt cccatatttt cacttcgctt tctgatttga
     9421 tagtttcata acgcaaaaac gtcctgttcc attatacttg tgaatcacga ttctgtgaag
     9481 ctttttttct ttcttccttc attcttctca tttttagtca attatctata ctcggattgg
     9541 gatttgcccg aaattctgtt ccggaatatt gcctcccaat tgatagattt gatcacttct
     9601 aactaacagt tccgcttctt gtgcctcttt ttttccgatt cgggaataaa tagaaatctc
     9661 ttttttttct tttaagaatc ttcttccagc atcggtaaat ccaagtagtc gaagataatt
     9721 tttattttgt tggacaggaa tctcttgctt tttgatattc agcaagacat aacaagataa
     9781 tcgttggatc cgtgtccatg tatatctttt tgtttttacc tttgacacaa aatcctcaaa
     9841 actatcagca gttgcagctg ctgttttcat gcgcgattct attccttcgg tcatctgata
     9901 gatatctgtc agttccagca aagtagaaga taacaaccga taacgcaaat acggccaata
     9961 agattcccaa gtctgcagcg aacaagttga aagatcttct tctgtctgag gcggcacaag
    10021 tccagctatt ctttttcctt cttctaacgc atggcgaatg gctgttgcac tggctatcct
    10081 ctgatctgtg atgatttttt catgatagcc tgcactttta cgtcggatcg gatgtaattc
    10141 catagggtgg acatacttgg cattttcctt tgcataactt aatcccaaga tatgatttgg
    10201 cgaagaaaaa tcaagcgtaa tatcgggata cagactgcga aaaacctcag tcattttttg
    10261 cggataacta tacgtttgat cagacagttc ttgaaatgcc tcttctatcc tatcttgatt
    10321 ctcttggaca aagcgtccga aactgctgta atcaaacgaa gtctcttctt ctgttccaaa
    10381 acacaaactg tcacagtcca gtgtttgcaa gatttttact gcacctttag caaaatagtc
    10441 agctgactga accgcccatt cgacgggaag ctccactact aaatccacac cattttgtaa
    10501 agcttcattc gcgcgatgcc atttatcgat gatagccggt tcgcctcttt gcaaaaaatt
    10561 cccgctcatt acagcaatga cgacctctgc tcctgttatt tttcgtgcca tttccacatg
    10621 atagcgatgt ccattgtgaa aaggattgta ctctacgata atcccgcagc ttttcatgcg
    10681 catcctcctt catagttatc gataaaaaag aaatagagac aagtaaaaaa aggcaaaaat
    10741 cggaaaaaat acccgaacta tataaactat tctcgcaaac acaatacttc tgcgacgaaa
    10801 agctgcactg caagagcaat gcctatatcg ttcggatata taatttatgt tgaagattta
    10861 ttcttttctt gttaactcga gcaggcaaaa ccgctagtct ttgtatgcta caaagaacca
    10921 gcgctttgat ttctctgatg ctgcttcgtc tgtaaaatca gaaaatgctt cgactttcga
    10981 aaagccgctg ttttccagca ttcttaaata actttccaat ggataggtac gctcttgatg
    11041 tagttcatct tcacgaataa atcgaccaga cccttcttgt tcttcaacga aaaaggtaag
    11101 aaaatgttcg atgctgtgtt tctcgcttcc tggataacta tcccacaaaa aagcaaaatt
    11161 atccccttga taatgatagc tatattctgg aaaaacctca tctacttgat aggtggagtg
    11221 tacgtcaaat aaaaatcggc cattttcttc taacgcttga tagacttcat caaacacttg
    11281 ctgtacctct tgtctatttt tcatatagca cagcgaatca gaaaaacagg taattgcctg
    11341 atattgtccg atttctgata aatcgagcat attgccttcc acaaattgga tcgatgcgtc
    11401 ttcttcatat gctcgctggc tggcaatcat caacatctct tctgaaaggt ctaaccctgt
    11461 cactttatat ccatcttttg caaaggcaac cgctaatgct ccagtaccgc atgccagttc
    11521 caaaatattt tttgtgtctt cttgtaaatg acgtttcgaa aaagctaacc attgctgata
    11581 aagtgtttcg tccatcactt catcgtaaat gaaagcaaat gtttcataag ccatatgtta
    11641 atccaaccat tcactaagat cgactagcgg agcatctgac catagttttt ccagattata
    11701 gaaatttcgt tctggcgcat ggaaaacatg tacgatcaca tctccaagat cgatcaatac
    11761 ccattttccg ccttcttttc cttcaatacg ttttacttca tatttgtttt cttcttcttt
    11821 atcaatgatt tcttctgtaa ttgcgttgat ttgacgttcg ctatttgctg aacagatcat
    11881 gaaataatct gccaacaagg aaacatttcg aacgtctaaa gcgataatgt cttctgcccg
    11941 ttttgaatct gctgcttcaa tcgcaatttt taattgttct ttactatcta tgatgatttc
    12001 ctcctaatat gagcagctta tttttttgct acccagtaat tatatgtttc gattgttttt
    12061 ggataaatct gttgttcttg cgcaagcaaa tgggccaatg tatgttttgt ttcaaatgct
    12121 acagcttcgt ctagatcagc ccatgcaatg gctcgtgcat cttgtacccc aggaaaatct
    12181 cgacctggtt caatatagtc tgctacataa atgattttgt caaggagact catcttagca
    12241 gccccagtcg tatgcacccg gattgcatga agaatctctg catcggtgat tcctaattcc
    12301 cgctctacaa acgaagcgcc aacaagacca tgccagattg cattattata attcaataac
    12361 tccggatcaa aaccgtctct tacgattacc attttgaact cctcatctgg tcgttctttt
    12421 gcataatcat gtgtcaatgc agcaatacta gctttttcag gagaagcacc gtattttttg
    12481 gcaagagcca cggctgtttc ttctactcca agcacatgct tgaagcgttg ttcgctcatt
    12541 ctcatctgta ttttttgcat caggttttct ctagaataag cagtatattc attactatag
    12601 tccatattca tacaaccctt cattttgaat ataatcaatt actttatctg gaacaaggta
    12661 gcggatagaa cagccttctt tgatcttttg acgtattttc gtggaactga tgtcgatctc
    12721 aggtacatct acccaaatta caggatatgg agtatccgtt gtgtatcctg gtcgacgtat
    12781 acccacaaag ttgaccatag aagtcagctc atcgatttta taccattttg gcaaatattc
    12841 taccatatcc ccaccgataa taaagtaata atctgtatcc ggattgtttt gcgtcaattc
    12901 cttcatagta tcataggtgt aacttttccc accacgagct aattcaatcg tttcaatctg
    12961 caaaaaagga ttgtcttcca ccgctaattc caacatgttg agtcgatgtt ttgcatcaat
    13021 cgtctgtttc tcatcaacat gaggtggctg ataagaaggc atcaaaaata cgcggtcaag
    13081 acctaaattc cggccagctt gttcagccat cactaaatgt gcaaggtgaa cgggattgaa
    13141 tgttccgccc aagatcccta cttgcttttt cttctctaag aattgaggca tttcttcagg
    13201 aaataattgt gaacgaacaa atgtcttagc ttgcgtattc atcatggtca ctccttatat
    13261 tgcttttact tcttttgata gcctttgata cttttctttt gtggaaggtt tgtataatac
    13321 aataacacgt ccaatgattt ggacgatttc gcaatctatt tctttttcta atacttgagc
    13381 tgcttcttct gcaatctcat ctgtattttg aagtaacgat actttgatca gttctctttt
    13441 ttctaaagct tcttcaattt gaacgatcat tgctgaattg atcccacctt ttccgatttg
    13501 aaaaatcggc tgaagatgat gcgctttgct acgtaaaaaa cgcttttgtt ttcctcttaa
    13561 actcataatt ttccttcttc cttaaatcaa tgctttgcgt ttcaatacat ctacaccctt
    13621 tggcgcccag cccgcaatta ctactggcgc tgttacagtg atccagccta gaccggcaaa
    13681 aacgatgtct gttttttctt tcacagaaaa ctcaaaacga acaagctccg gaaatgcctc
    13741 gacttcatca ggacgaggag gctgtaataa tccacctaca tgtttttgat aaaattcgtc
    13801 tgctttttcc agtttcgttc gatgaatatt tacatcattt gacacataag caataaatga
    13861 agcacgattg ccgctgataa aatcaaatct tgcaagtccg cccaagaaaa gtgtttgccc
    13921 ttcattcagc tgataaactt taggtttgat ttcttttaac ggtgcaatga tccgcaaatc
    13981 ttttttacct aagtagtgcg ccatttgatg gcgatggata attcccggtg tatcaatcaa
    14041 aaaatgcccg tcatctaaag gaatctcgat tttatccaag gtcgttcctg gaaactgcga
    14101 agttgtgatt acatcttgta ctcccgctgt atttttgatg atttgattga taagcgtcga
    14161 ttttccgaca tttgttactc cgacgatata gacatcccgt ccatcgcggt attcttcgat
    14221 tttttctaat agttccgtca tctcatgaga tttcttagca ctagttaata atacatctac
    14281 tggacgaatt cctgcttcgt aagcacgttc cttcatccat tgtgttaatt tagttttttt
    14341 caatgattta ggtaatatat ccactttgtt cccaactaaa agtactggat tgtcaccgac
    14401 aaaacggtgt agtcctggga ttagtgaacc attgaagtca aaaatatcca ccacattgac
    14461 gatcaatgca tctttttgcc ctaattcatt cagtaagcgc aaaaagtcgt catccgtcaa
    14521 tgagacatct tgggtctcat tataatggcg taatctgaaa caacgctgac aatagacttc
    14581 cccggaagct aaaccttttt ccaaagccgt ttgcggcgtg tatcctaatt caccgggttt
    14641 gtttgtttgt ataacggcac cacagccgat acattgtaat tcttctgtca ttcgattcca
    14701 cctcgccagc ccatatcagg gtgttttgct aatagatagg ccataattct tttttcccaa
    14761 aaacgattaa attgtgtctt ccaactatct gttgcgataa tgggttttac aaggatgcta
    14821 cgtatccctg cacgattggc tccacgtata tcagtcataa tctgatcgcc taccattact
    14881 atctcatcat ctgctaaatc caattgtttc tttgctatgt tgatccctct tgctaaaggt
    14941 ttcattgctc gtgcaacata caaaagatca aatttttcaa tcgctcgcgc gacacgtttt
    15001 gaattattgt ttgaaacaac aacaacaggg attcctgcat ttttcatttc taaaatccaa
    15061 gtaagcaact cttctgttcc atctggatta ttccatgcaa tcaacgtatt gtctaaatcg
    15121 gtcaatactg ctttgatgcc tagattcttt aattgggcag gtgtaatctg atagatggct
    15181 tctaccatcc atgttggttt gtaatttgaa aacatgctgt ctcctcatct gcaaaaaatg
    15241 aaggagcaca taaagtactc ctcaaccccg tattatactg catatcagca aaaaaaacta
    15301 cctctatact cgttcgtctt tcagaaaaag catttcttta caaaatgacc aaaaataaag
    15361 attgatcaca gaaaaattta gaaacaaaaa acaactaata ttggcggaac ctcttgtatc
    15421 gtttttccag taatttatgc tgatctaatc gaacaagttc cgtcaatctt tcaatcaacg
    15481 cttttttcat aatgtgtgcg actttatatc gtggcaactg ctcgccgttg aacgtttcag
    15541 gaataactcg atcaacgatt cctaactcgc gtagttctgg cgcagtaatt ttcatcaact
    15601 cagctgcttc tgcggcgcga ctaccgtctt tccacaaaat cgacgcaaat ccttctggag
    15661 aaagcacagc ataaatcgtt tcttccagca tccagacttc atccgctaaa cctagagcaa
    15721 gggcaccgcc acttccacct tcaccaatga tgatggcgat gatcggtacc tttaaatcag
    15781 acatttcgag cagatttctg gcaatagcct ctccttcgcc gcgctcttct gctcctacac
    15841 cgcaatatgc acctgctgta ttgatcaagg taatcaccgg tctattgaac ttttccgctt
    15901 gtttcatcag tcgtaaagct tttcgatagc cttcaggatg gggagaacca aaatttctgc
    15961 ggatattttc ctgcagatcc cgtccttttt gaataccgat cactgttacc ggtttgccat
    16021 ctaatcgagc gattccacca acaatcgctt cgtcatctgc aaataaacga tcaccatggc
    16081 attcctcgaa agaatcgaag atctcttcaa aaaaatccaa gcttgtccat cgttctttag
    16141 ctcttgctaa ctgaacgaca tcatgtgctg tcttatccac gatctatcca tcctttctgt
    16201 gtatgcaatt caagaagcgt atggattttc tgtttcaatt ccatgcgggg aacaatctga
    16261 tcgacaaaac catgagataa taagaattca gccttttgga aatcttctgg aagttcctgc
    16321 ttgatcgtct gttcgatgac gcgtcttcca gcaaaaccga tcaagctttg gggttctgct
    16381 agaataatat cgccttccat tgcaaaactg gcagttactc ctccggtcgt cgggtccgtt
    16441 aaaacagtta gataaaaaag accttcattg ctatgccgtt tgacagcagc agagattttt
    16501 gccatctgca ttagagaaaa gattccttct tgcatccgtg cgccacctga agctgtgaac
    16561 aagacgactg gaagactttc ctttgttgct cgttcgaata atctggtgat cttttctccg
    16621 acaatcgttc ccatacttcc catgataaaa ttaggatcca tcactccaat aatgaaggga
    16681 atcccctgaa tggttgcttt accagtgagg actgcttcat gaagtcctgt tttatcttgc
    16741 atttttttaa ttttttccgt atattcggga aatgctagcg gatctttggt tacaagatcc
    16801 gtatcccatt cttcaaaact tttttcatca ataatcaaag ctagacgctg ccatgcaccg
    16861 attcgaaaag cgtatccgca atgagggcat actttttctt caccgatgtc tttcgtataa
    16921 aggatatgtt tgcaatttgg acactttgcc cacatgttat caggaacaga tggcgagtta
    16981 gcaggtttgc tctctctatt aggattgatc cgaatatatt tctttttctt aaacagagcc
    17041 atctatgcgc ctcctatctc cgtttctggt gtccaattcg gtaaaaattc ttcttgtaaa
    17101 aatgctgtgc tgtaatcacc tgctatgact gcaggatgac taatcaaatc catctgaaat
    17161 tctgcgttcg tgatgattcc ttctgtgata aattcactta aggctcgctg catcttcatt
    17221 aatgcttcaa aacgcgtatt tccatggacg attatttttg caatcattga atcataatat
    17281 ggcgggatcg tatatcccgg gtaaactgca ctgtctactc gcagtcccat cccacctgct
    17341 ggaagcagta agttttggat cttccctgga gaaggagcaa aatggaaagc aggattttct
    17401 gcattaatcc ggcattcgat tgcgtgtcct tggaatacta cttcttcttg acacacattc
    17461 aaaggctcac cggctgctat ctccacctgt ttttttacta aatcgattcc tgtgaccatt
    17521 tctgttactg gatgttccac ttggattcga gtattcattt ccatgaaata aaaatcgcct
    17581 tcttcatcca tcagaaactc gatcgttccg gcattttcat aattgactgc tttagctgct
    17641 cgaacagcag cgtctcctag tgcttctctt tttgtttgtg agatcactac agaaggagat
    17701 tcttccagta ctttttgatt gttgcgttgt aaagaacaat ctcgctcgcc taaatgaatg
    17761 acatgaccaa atcgatcacc taagatctga acttctatat ggcgagcagg ataaatgatt
    17821 ttttccaaat acatatcatc atttccaaat gccgctgctg cttcttgctg agctgaagaa
    17881 aaatgctgtg ggagctcttc ttttgattga actttccgaa tgcctttccc gccaccacct
    17941 gcagctgctt tcagcatcac tggataacca attctgtctg ctatttccaa tgcttcttct
    18001 actgtagata atacaccagt acttcctgga atgactggga catttgcttc ttgcatcaat
    18061 tgacgcgcat tgatcttatt tcccattgca tcgatcgttg cacttttagg accaataaat
    18121 gtgatattgc actcttcaca catggaggca aatcggctat tttcagataa aaaaccaaat
    18181 cctggatgaa ttgcttcggc ttttgtcacg attgcagcgc tcagtacttc ctgaacattc
    18241 agatatgaat caacggcttt tgccgggcca atgcagattg cttcatctgc taactgtgta
    18301 tgaagtgctt cggcatctgc ttctgaatat atcgctacgg tttggatccc tagttcgcgg
    18361 catgcacgaa tgatacgtac agcgatttca ccgcggttag ctatcaatac tttagaaaac
    18421 atatttcacc tatccaatca taaaggttaa ttccgcttcg gctacttttt taccgtctac
    18481 tttagcgatt cctttgccta ttccggctga agctttcact ttcaatatct caacttcaag
    18541 gtataaggta tctcccggtg taactttctt acggaatttt gctttgtcca atccgccgaa
    18601 ataagccgtc tttcccttga attgttcaag agaaagtaat gcaactgctc ctgcttgagc
    18661 cattgcttca acaatcaata cccctggcat aacaggttct tctggaaaat gtccttgaaa
    18721 aaagggctca ttgatcgtta catttttctt agcaacgatc cgttctcctt caaccatttc
    18781 ttccactcga tcaatcaaaa gcattggata acgatgtgga atgatttctt ttatttcttg
    18841 tatgttcatt gttttccctc tttcctgctt tgcttatttt tgctgaatcc taaagagtgg
    18901 ctgtccatat tcgacaactg actcgttttc tacaaggatt tctgtgatca ctccgtcggc
    18961 ctcactagtt atctcattca tcagtttcat cgcttcaata atgcagataa cttctccttt
    19021 ggcaacttga tcacctactt ttttgaaagc tggtttgtcg ggcgctggtt gcagataaac
    19081 gattcccacg attggcgaaa caacctcgat tccatcaaat actgccgatt ctttttcttt
    19141 cattatttct ggagcagttg ttgcttgttc aggtatgaca ttgactggct ccgaaactgg
    19201 caacgtttcg tttgtttgaa ccatattcat gcctcgactt gttttatttt tattcatata
    19261 caattcaaat tgaccttcac gcaaatcgaa ttccgttagc gaggattgat caaattgact
    19321 gactaattct ctgatttcat tgatatccaa aattattcct cccagcgttt catgcacaga
    19381 accgcattat gtccgccaaa ccctaatgaa ttactcattg cataagtaaa acttgcaggt
    19441 ttgctttcgt ttttgacaac tgtcaagtca atctcaggat cttgtttttc tacattgatc
    19501 gtaggtggga taaattgatg ttctaatgcc agcaaagttg ccaaggcttc gatcccgccg
    19561 gctgctccca ataaatgtcc agtcatcgat ttcgtgctgc tgacgtaagt atctctgaaa
    19621 ttttcaccta atgcgatttg gattgctttt gcttctgcct ggtcattggc tggtgtactt
    19681 gttccgtgag cattgatata tccgacttgt tccggctgta caccagcttc ttccatcgca
    19741 agcttcattg ctttagatgc accagaacca tctggagtag gagctgtcat atggtaagcg
    19801 tcacagtttg caccgtatcc aacgatttct ccatagattt tggcaccgcg agcttgtgca
    19861 tgttctaaag attcaagaac tagaacgcct gctccttcac ccatcacaaa accattccga
    19921 ttttcgtcaa acggaatcga accacgatta ggatcagttg attctgagag tgctgttaaa
    19981 gctgcaaatc cagcaatccc catctcacaa atcgttgctt ctgttcctcc agcaagaatg
    20041 acatcagaat agccatgttt gatgttacgg aatgcttccc caattgaatt cgttccgcta
    20101 gcacaagctg ttacgatagc tgtacaaata ccttttgcac ctacacgcaa agcaatattt
    20161 ccagctgcca tgttggcaat cgccattggt acgaacattg gagaaactcg ttttgcacct
    20221 ttttcatgta gacgaataac ttggttttcg attgttggaa gaccaccgat cccagatccg
    20281 atgatgacgc caaaccggtc ttgattcatt ttttctttat ctaaaccgct catctccatt
    20341 gcttctaaag cagcgtagat tccatagatc gaaaacatat ccattcgttt gctatctttt
    20401 ttaataaaat atttatcgta agggaaatct ttgacttcac ccgctaaggt aatccctgtt
    20461 tctgaagcat caaatttagt gatcggtgcg atgccattcg tcccctcttt taagctattc
    20521 aaaaagctgt ctgcgtcatt tccaataggt gaagtgactc catagccagt aattaccact
    20581 cgattcattt gtttgctctc cttttcttat ccgtgcatga ccaatccgcc atcgacattg
    20641 atgacttgtc cggtgatata tggattttgt gctaagaaaa ctgctgtttg tgcaatatct
    20701 tctacttgtc cgaaacgctg catcggaatt tgcttttccg cttgttcctt gactttgtct
    20761 gctaaaactt ccgtcatatc agttgtgatg aatcctggcg caatggcatt acatgtaatg
    20821 cctctagttg cagcttctcg tgccacagat tttgttaatc ctactacgcc agctttacta
    20881 gctgcataat ttgcttgacc aatatttcca atcaacccag atacactaga gagattaatg
    20941 atggcccctt ctcgctgctt catcattttt ttcaatacgt gctgcgtcat attgaaggtt
    21001 ccaatcaaat tgatatccag acattttttg aaatcttctg catccattcg catcacaagt
    21061 ttgtcatttg tgattccggc attgtttact aacacatgga tcgatccaag cttttcttct
    21121 gcttctttga tcatttgtcc cgctttctca taatcagaga tgtcaccgga aactcctacg
    21181 cattttacac cgaatgcttc gatttcttct atcttttctt ttggaatctc tccgcgacca
    21241 ttcaaaatga tatttgctcc agcttttgca aaagctaagg ccatcgcttt gccgattcct
    21301 cttgtactac ctgtgataaa tacatttttt ccttttacat ccataacgtt cctccttata
    21361 gtattgctat tgtttcatca aatgtctgct tattctcaac acgcagaact ggtattgttt
    21421 tatcgatttt tttcataaat ccgcttaata cttttccggg gccgacttcg atgacttgtt
    21481 cgatgccgat tgtttttaac ttatggatac tctcatagaa acgaacaggt tgcatgactt
    21541 gctgttcaag tagtcccgcg attgtttctt tcttcattat ttccgttgtt gtgttgctta
    21601 tgataggaaa agaaggttca gagaattgaa tctgacttag gtccttcgcc agtttttttg
    21661 ctgccggttc taaaatagct gtatgaaaag gcccgctgac atttagaggg atcattcttt
    21721 tgaacccttt ttcttttaat agtaaaacag cttcgtctac tgctttttct tcgccaccaa
    21781 tcacgatctg ctgaggtgta ttataatttg caggagatac gatgccgtac ttgctagctt
    21841 catgacagct ttcctcgatc gtttcaatcg gcgcattcat cactgcaacc attttcccgc
    21901 ttccagctgg ggcagcttct gtcatataag cgcctctttt tgctactaac gcaactgctt
    21961 cagtgaagga tagcgcatta ctagctacta atgccgaata ttctcctaaa ctcagtccta
    22021 aagctgcatc tgggatgatt ccatgctcct tcaataagcg ataatacgcg atgctgactg
    22081 ttagaatagc tggctgtgta tattgcgtct gatccaaacg ttcattttct gtaaagcaaa
    22141 gttcagccat atcgtagccg agaatctcac ttgcttcatc aaatgtctgc tttacaacgg
    22201 cttcttcata taaatctttt cccatacctt gatattgtgc accttggcca ctaaataaga
    22261 atgctgtttt catgtttttc tccaatatat ccagaatata tgtttgattc ttcctattca
    22321 aaaaggccga gacattccta tttcaggaaa tgtcccagcc cccaacctaa ttttaatgat
    22381 tatgcagttt gtttttctac gtaagtcact aaatcttgaa ccgttttgat tccgtcttct
    22441 gtttcgattt tcacgtcaaa ttcatcttca atttcattga tgatttggaa taaatccaag
    22501 ctgtcagctt ctaagtcttc ttggatgtca gtagtcaatt tgatttcttc agtttctttt
    22561 cctaattctt ctgcgatgat ttcttgaatt ttttcgaata ccataataat atattcctcc
    22621 gatattgttt gctttttatt tttataattt aacagtctac aactccatga gaatacttcc
    22681 ccatgttaaa cctccgccat agcctgtaaa tattactttc tgctgttttc ctaaggtgat
    22741 ctttccacta gaaactgctt catccaataa gatagggatg cttgcagcag atgtattccc
    22801 atatttatcc atattggtca ggaacttttc ttgcggcatc tttacttttc gggcaatttt
    22861 ctcaataatt ctgaggtttg cctgatgcaa aagcagataa tcaactggtt tgtctttcat
    22921 gacttcttgg atattgtttg caacgtctcg tacggcaaaa tcaaaaatat ctctgccagt
    22981 catttgcaaa taatacgaac cttctgaatc ttctgaatag aacggatttt tattttgctg
    23041 gtagccagcg gtcaatgagc tacttctggt accgtcagct gctaattttt ctttcagcaa
    23101 ttttttctgt ggattcgctt ctaagagaat cccacctgct ccatcgccaa acaacacagc
    23161 agtcgtacga tcagaccaat cgattagctt agatagtgtt tcaccaccaa tcaccagtcc
    23221 cttagttgag ccgcagcgga tcattttttc agccatgctt aacgcataaa caaatcctga
    23281 gcacgcagca ctgatatcaa aagcgatagc atgagttgct cccaatttcc cttgtacttg
    23341 tgctgctaca gatggtgtcg tgtaatcggg cgacattgtt gctactaaaa taaaatccaa
    23401 atctttaggg tttagatttt tctgttttat caatttttcc gccactaaaa tgcataaatc
    23461 agaagtctcc tgatttgtta cacatcttcg ttcacgaata cccgtccttg acgaaatcca
    23521 ttcatcagag gtatccatca tcttggaaag atcattatta gtaataatct tttcaggaag
    23581 gacgctggct gttgcagtaa tcattccaaa ttgttccatt aaatatcctc acttatagtc
    23641 ttgcaagaag tcgtgcaagt ttttcagtgc atccagcaag gcatgctgtt cctccgtagc
    23701 cattccgtct aagatgttct tgaccatttc acgatgaaaa tgctgatgga cccgaaatag
    23761 taactttcct tttttcgtta gtcccaactt tacaacgcgg cggtcatctt cactgcggat
    23821 acgttcgaca tagccttttt ttactaactt gttaatagca gtggtcaagg tcccaacagt
    23881 aattgatagt tctttggcta cttctgaagt tgtttttttc ttgtacatcc cgattgcctc
    23941 gatcgtgtgc atctctgtga ttgacagatc tttgaattga gattttttca gctcagactc
    24001 ttcgattgtc aaaatatcat tgaagacact aacaagataa tcatttactg tttttaaatc
    24061 tggttccatg ttccaccgtc cactaattag tttgattatc aaatcttttg atgttcaaac
    24121 tatatcttaa cttttttcaa aatgcaacct taaaagatca tttttttact atatgagctt
    24181 tttttaagat tttactcatt taaaacaact gataaatcag catttataat ttcttttatt
    24241 agaaaaatca tctatctcac atattttgat tatcaaagta ttttctgtga acagaactat
    24301 agaattccct aaaacttgtc cattatttca aaatttgtta tagtcttttt attcaaagcg
    24361 taaaaggaga tcctatgtta aaagaaaaaa tgaaaactct ccccatgctg ccgggtgtct
    24421 atcttatgaa agaccgagat ggtaaggtca tctatgttgg taaagcaaaa cggctcaaaa
    24481 atagagtaag cagctatttt catcagaata aacagcattc aaaaaaagta ttacgtatga
    24541 ttcatcatat aacagatttt gatttcgtcg tagtagacac ggaattagat gctttattgc
    24601 tcgagtgtca attgatccaa cattaccgtc ctttttataa ccgacaaatg aattatttca
    24661 gtaattataa ttatgtacat attaccaata agggatttgt attaacagat actcctacgg
    24721 ctcgaacata cgggcctttt cgtctctata aaaaaatgcc gtctattttg cgtataatgg
    24781 aagaaactta tcaaatgcct tggttgtctg aaattagttt gttagctttg cgagtccagc
    24841 ttcctgacct acaggaaatg acttttgaac agaaaaaaaa ggaactccaa gggctgtttc
    24901 aaggccgaaa taaaaagcta ctgacttact tgaaaaaaag acaacaacat ttcatctatc
    24961 agttgaattt cgaaaaagcc ggtatgcttc aaaaagatat cgaattagtt acttatttta
    25021 ttagacggat ccaggaacaa aagcagtttt taagaacacc atcgctcacc ttcagcatgc
    25081 cattagcagc agatgagagt cagaaaaagc actacctcgt ttgttatggt caacttgcag
    25141 aaacaatgat tacctctggt gacgtttctc ctgacttcta ttatgaaaag aaagaagctc
    25201 atttatcttt gaaacgtcaa ttgtcaaaag aagaaatcga tcctgtacaa atcttgatca
    25261 gttaccgcaa aaaattagaa aaagaacagt ttgaaattga actgttaaac aaaaaagaag
    25321 ctgaaaagca actaaattag ttgcttctcg gcttctttta ggcatcttca acttcaaatg
    25381 tcaattatcc taaaatttat tggattaagt catagatttc catcgctacg atatcgatat
    25441 tatcaaattc gtattgctga tgagtatctg tttcagttaa ttcaaatgta tcggtcgctt
    25501 tatcataagt tactgtacac ttctctacgc cttctttttc aaaacggcga acttgcagtt
    25561 cattatctgc tgactcgacc atagcctcca gtcgttttat gattgcgact aattgtgaat
    25621 gtgtcatcgg aggtcctcct tttcttattt ctgttatatt gtatcaaaag catagcctac
    25681 ttgcattgat tttctctaaa aaaactcgtt ttttatgatt ttttttctgg tatttttcct
    25741 tcaggccacc aaagtttgat caaagcttgg gttccgtcat tctcaaaacc tttatctgcc
    25801 aactcttcat atagtttcaa tgcttgggta gttgctggca atacaagatc cattttttct
    25861 gcttcttcta atgcaatctt taaatctttg ataaaatgtt tgacaaaaaa accaggtgtg
    25921 taatcttctt ttaaaatacg aggagaataa ttgcttaaag accagttagc tgcacttcca
    25981 cctgaaagcg tctcaatcac tttctttaaa tcaagtccgt ttttttgtgc atagacaagc
    26041 atttccgtca ttcctgtcat cgtacctgca atcatgatct gattagccat ttttgtatgc
    26101 tgacctttcc cagcagaacc atgcaatgta aatgtcgtac caaattcttt gaataaaggc
    26161 agtacttgat cataaacggc ttcttctcca ccgaccatga tcgtcagtgt accattcttt
    26221 gctcctaagt caccaccgga taccggtgca tctaacgcat ctgcgccttt ttcttttgct
    26281 gtttttgcaa ttttttctgc caggcttggt gtacttgtag tcaaatcaac taaaatatgt
    26341 cctgagatat ctgcagaaaa aatccccgac tgtccatagt agatttcttc tacatctttg
    26401 gggtaaccta ccattgtaaa gagaatatta ctttgttctg ctaccgcttt tggtgtatct
    26461 gcccagatag ctccttctgt tactaaagga tcagcttttg cttttgtccg attatagaca
    26521 gctacttcgt gtcctgcttc tagtagatgg cgtgcgacag cacttcccat gacgcctgtt
    26581 ccgataaaac caagtttcat tttttcgacc tcctaaaaat caaaaatcct tgcttctatg
    26641 ctagtatacg ctagaaacaa ggattttttc ataaaaaatg tttgaatttt atcttttaaa
    26701 tgaatttaat tttattttga ttcgttcaat cgagtcttct tcttcttttc ttcgcatctc
    26761 ttcttcatga taaacaacca tgtcttgata aaattcgatc atagcttcgc cgaaatgtgt
    26821 agatgaaata tcataaagtt tagcttctaa aacttttgga tctttaggaa cttcactgga
    26881 aatataatca ataagtgctg gtgcaaagtc ttcgtcggtt tcaaaagttt tccctaatga
    26941 aggatgatcg aacaatcggt tcaaataagc atttccttcc acgacacaag gtgttccggc
    27001 tgccatcgct tctgtataag taagcccttg tgtttctgaa gtagaagcac tgacaaaata
    27061 atctgccgct ttataataaa gtgctacatc attgttgtcc acttctcctg tgaactgcac
    27121 aaattcttct aactgcagtt ctgagatcaa ttcctctaac tcttctacat aaggtccttt
    27181 tcctacgata actaatctgg cgttaggata agcggagatg acctgaggaa acccattaat
    27241 caaggcttgg atatttttct cataagaaat cctgcttaaa gaaagaatca tcaaatggtt
    27301 ttcctgaaga cctagtgact cccttaattt gctgatatcc tgctgagtga tatcagaacg
    27361 tttgaatttt tcaatgtcga taccagtagg aatcacgcga agcggtgcta ttacaccata
    27421 gctgcgtaat gtatcaataa cacgttcact tggacaaact acacctgtcg tatgatttgc
    27481 aaataatcta gacaagtatt ttacatggga ttgcctgatc acttttcctt taccgatata
    27541 atgaaggtag tcttcataca tcgtatggta agtatggatc agaggtattt tcaacttctt
    27601 agctaccatc ttcccaagta tccctgctcc gaattctgta tgggtatgaa taagatctag
    27661 ttctagttct ttggcaacca aataagcata ccacatgcct ctaacaacaa ctcttcgatc
    27721 cttgaaagaa ataaatggta cacttggcat tcgaatcaca tctttttcca acttatccgc
    27781 attaggatcg gtcgttgtaa aaatatagac ttcatgccca tgtctttcta attcttgttt
    27841 taatgttttg atcgatgtag caactccgct gacttgcgga aagtaggtat cggtaaaaaa
    27901 gccgattttc atgtttttcg cctccaaact agtccttgac ctgatttact ttttttaatt
    27961 tgctagagac tttttcattc agtacacttt cgtatacatt tttaagttct tcaccgattt
    28021 tattgatact tcgctctttt gctgtttgat aaccggcttg tgtcgtactc ggtagttctt
    28081 gattggtaat ctgttggatc agtcggataa attcttcgtt tgtcttcccc atatagcagt
    28141 tcttgctatc ttctaaccag ccattataca ctggaatatc tcgaacaagt acgttttgtt
    28201 tgcttgctaa agcttctaaa acaacgatcc cttctgtctc ttcataagaa gggaaaaaga
    28261 atagatctgc acctgaatac gcaccttcta tgatctctcc acgaatgtaa ccaggaaaca
    28321 ggacattttc aggatgatct tcttttacaa ttttccggat gttccgagga atcgagtaca
    28381 tgggaacatg accaaaccaa ataaatgtgt attcgggcat cttcttagca atttctacga
    28441 aatcaatgat tcctttacgt tcgaaaaaca aaccgacaca aatgattact ttttgatccg
    28501 gagacagttt gaaatattct ctgaactttt gttctttcat tggatcaggg tgatatttct
    28561 ctaagtcgat cccattggaa atagcttgaa tcggcacacg gataccatag ctttccaaca
    28621 actgttttga ataaggtgtt ggcgtgatca gatagtccgc tttttggtac aatcctacca
    28681 gatatttttt tacgatagga gaaagctggt tcgatctgat aaaggaattt cggaaatctt
    28741 cctctgtaga atgcgcatga tagacaactt tttttccttc tcttctggct ttattgacca
    28801 tattatgact attgattccg tatgtattga tgtgcaggat gtcataatct tctttttcat
    28861 ctagtgtata agagataccg acttccgtca gagcacgttt ttgatgatca agcgcacgcc
    28921 cgattccaga ttttgcaagc atcttttcac tttcaaaata taataatacc ttcaccttac
    28981 gtcccccttc acttatatag tataacatag cctacaaact gtcactcaaa cttaagccct
    29041 atttttgtct attcttactg acaaaaacgt tttcttaaaa aagaacaaaa aaactggcgt
    29101 agctctttta caagccacac cagcttttga tacgttgttt attttacata ttcatgaaca
    29161 agttcaacga cttcttccat catatcgcat tctttcaatg cacgatcagc aagttcagcc
    29221 attttcgctg tgtccaagcg tttcattaaa ctacgcgttt taagaataga tgtcgcactc
    29281 attgagaact catctagacc catacctact agcaatggaa cagctgtttg atctccagcc
    29341 atttctccac acatacctgc ccattttcct tcagcgtgtg ctgcatcaat tacatttttg
    29401 atcaaacgta aaattgatgg gttatatggt tggtacaagt aagaaacgcg ttcgttcata
    29461 cggtctgctg ccattgtgta ttgaatcaaa tcgttcgtac ctacagagaa gaaatctact
    29521 tcttttgcaa acttgtctgc taagactgct gctgctggaa tctcgatcat gatgccgact
    29581 tggatcgtat cagatacttc cttgccttca cttatcaatt tttgtttttc ttcttcaaag
    29641 atcgcttttg ctgcgcggaa ttctttgagt gtagctacca tagggaacat gatacgtaaa
    29701 ttaccatgaa cagatgcacg aagcaatgca cgcatttgtg tacggaacat ttcgtcgcct
    29761 tgttcagata aactgatacg caatgcacga tatcctaaga atggattcat ttcatgaggt
    29821 aattgcagat atggtagttc tttatctcca ccgatgtcca ttgtacgaac aactacaggt
    29881 tttccttcca taccttctaa tacagctttg taagcttcat attggtcatc ttctgttggg
    29941 aagtctggag aatccatata caggaattca gtacggtaca gaccaactgc ttctccacca
    30001 ttattatgga caccaactag atcttttggt gttccgatgt ttgcagctaa ttcaaaatgc
    30061 ttgccgtcag ctgtgacagt ttctgcattt tttaattttt cccattctgc tttttgtgct
    30121 gcgtaatctg cacctgcttt ttcaaattca gctttttgtt catctgtagg atcgatgatt
    30181 acatcgcctt cgatcccgtt gacagccaaa atatcgcctt ctttgacttt agcagtaatt
    30241 tcttttgtcc caacgattgc tggaatttct aaagaacgtg ccatgatagc agaatgtgaa
    30301 gtacgtccac caatgtctgt tacaaacgct tttacaaaat tgcgatctaa ttgtgctgta
    30361 tcacttggag tcaagtcatg tgcaacaacg accacttctt cgttgatcat tgatggattt
    30421 ggtaaagtaa cgcctaataa gtgcgctaaa atacgtttag caacgtcacg aatatctgca
    30481 gcacgctctt gcatataagc attatcttcc attgcttcga acataccgat atacatatcc
    30541 gttacttctt ttagcgctga ttcagcattt acgctgttgt ctttaatatt ttgcttgatt
    30601 tgacctacca tttctggatc tgaaagaacc atcaaatggg catcaaatac ttgcgcttct
    30661 gcttcaccta agctttgcgc tgctttttca cgaatttgct gcaattcttc agtagattta
    30721 gctaatgcag catccaaacg agcttcttca gccgcagtat cttctactgt tgccttactg
    30781 aatgttaaat ccggttgaac tagcaggtaa gcttttgcaa cggctacacc gtcactagcg
    30841 gcaatccctt ttagcatttc aaccattatt cagataagcc ttctttcttc attgtttcaa
    30901 cgattgctgc cattgcatca gcttcgtcag caccttctgc agtaatagta acatcagaac
    30961 cttgacctac acctaaagac ataacgccca tgattgattt caagtttact gatttacctt
    31021 tatactctaa gtttacatca gagttaaatt tgcttgctgt ttgtactaat agtgtagctg
    31081 gacgagcgtg gatcccagtt tctgctacta cgtgaaattc tttcttttcc atattaatcg
    31141 gtctccttta agtgagtgtt gtttttatgt gagggttttc ttttttagta attcagagaa
    31201 tcctaacaaa tgccaccctt tcatctgtaa agattaacat tttttttcgt tagatacaac
    31261 agttttcatt caatttcaga taaaagtatt caaattattc cggattcttt ttcatccttt
    31321 tcttcacatt ttataacaaa cgtgtttatt tcctttttct tgtcgctttc tcttctcctg
    31381 acgtttatca ttctttcctt tgaccctctt tgttttcata tgaaacgaat tacttgcttc
    31441 cctttttatt tttagtataa taagagtcaa aggtcaggaa tggtcaatag agatttcacc
    31501 ttttctacct cataaatctc ttaaaaaact aggggttatt cttttacctc atgaaaaacg
    31561 agatgtaaaa tatggatgta cccatttttg tgaaaggacg tgaatgattc atgctttgtc
    31621 aaaactgcgg caagaatgag gcaacgattc acttgtatgc cactgtcaat ggtcagcgga
    31681 cacaactcga ttactgtcag agctgttatc aaaaaatcaa aaatcaacaa aatggaggtc
    31741 tgactaatat ggcccaaaat gatccatttg gatttggcag tttggacgat cttttccgtt
    31801 ccatgtctcg ccaaatgcaa cagcaaggaa attatgagca aacaccacca acacaatttg
    31861 gcggaaacaa caacttcaat ggtggtcagc cacctcaagg caatacagaa ggtttattgg
    31921 gagaatacgg aatcaatatc acagaacaag cacgacaagg tgatatcgat cctgtgatcg
    31981 gacgcgatga cgaaatcaaa cgagtcattg aaattttaaa tcgccgaacc aagaacaatc
    32041 ctgtcttgat tggagaacca ggtgttggta aaacagcagt tgttgaaggt ttagcacaaa
    32101 aaatcgtaga tggtgatgta ccgcaaaaat taatggacaa agaagtcatt cgtttagatg
    32161 tcgtatcttt agtccaaggt actggtatac gaggacaatt tgaagaacgt atgcaaaaat
    32221 tgattgaaga gatccgtcaa gcagaaaatg tgatcctatt catagatgaa gttcacgaaa
    32281 tcgtcggtgc tggttctgct ggtgatggaa atatggatgc tggtaatatt ttaaaaccag
    32341 ctttagctcg aggagaattg caaatggttg gtgctactac cttaaatgag taccgcatca
    32401 tcgaaaaaga cgctgcttta gaacgtcgta tgcaacctgt acgggtagat gaaccaactg
    32461 tcgaagaaac gatcagtatt ttgaaaggtt tgcaaaaacg ttatgaagac tatcatcatg
    32521 taaaatatac tgatgaggcc atcgaagcag ccgcaacttt atccaatcgt tacgtccaag
    32581 atcgcttctt gccggataaa gccatcgatt tgctagatga aacaggttct aagaaaaact
    32641 tgacgatcca aatcgttgat cctaaaacaa tcgagaaaaa actgcaagaa gcagaagaac
    32701 aaaaagtttt agcttctcga gaagaagatt tcgaaaaagc agcttattat cgcgatcaga
    32761 tcaataaact tcaaaaaatg aaagaacgtc agctcactga agaggaaaca cctgtgatta
    32821 ccgaaaaaga tatggaaaaa atcgttgaac aacggacagg tattccagtg ggtgaattaa
    32881 aagaaaaaga acagacacaa ctgaaaaact tagcagatga cttgaaagct catgtcatcg
    32941 gacaagataa cgctgtagat cgagtagcga aagcgattcg ccgaaaccgt gttggattaa
    33001 acaaacagaa tcgtccaatc ggctccttct tatttgttgg accaactggt gtaggtaaaa
    33061 cagagcttgc gaaacaactt gcctacgaac tattcggttc acaagattca atgattcgtt
    33121 tcgatatgtc tgaatatatg gaaaaacata gtgtctctaa attgattggt tctcctccag
    33181 gttatgtcgg atacgaagaa gctggtcaat taacagaaaa agtacggaga aatccttaca
    33241 gtcttgtctt gttagatgaa gtagaaaaag ctcatccaga tgttttgcat atgttcttgc
    33301 aaatcttaga tgatggtcga ttgacagatg cacaaggaag aacggtcagc tttaaagata
    33361 cgatcatcat tatgacaagt aatgccggaa ctggtaaagt agaagcaaac gttggttttg
    33421 gtgcggcacg cgaaggtgtt actcgttctg tattgaacca attaaacaac tactttacac
    33481 cagaatttct gaaccgtttt gacgggatca tcgaattcag tgcattatca aaagaaaact
    33541 tgatgacaat cgtcacacta atgctagacg atgtcaacca aatgctggca gcacagcaac
    33601 ttcacatcga agttcctacg aatgtcaaag aaaaattagt tgacttaggc tatgatccat
    33661 ctatgggtgc tcgtcctctt cgacgcacga tccaagaaca aatcgaagat ggtatcgctg
    33721 aattttatct tgatcaccct tctatccatg agttgaaagc aaaactggat aaagatggaa
    33781 aaatcatcgt tacttctaaa ccagaacgtt tggctaaaga atcagccgaa gaaacggctg
    33841 aataaatcca gttttatagc gtgagacggt atttctttga gaaatgccgt ctcattcttt
    33901 tttcagaaaa gtcaaaatac tgttcatttt ataaaaaaga aattataata agagaaacaa
    33961 gcaattaaaa atacataaaa gaggtgagcg ccatgaaatt ggtaaatgta acaaacagcc
    34021 attcccgtct tgtattaaac cagcttgaaa acactgatgc ccatctagtc aaggtctaca
    34081 cagccggaaa taccactatt gtctacactg aagcccctga acataatgaa attctgctga
    34141 tcaatgacaa acgtaaaatc cagccgaaag aaatcgaaga tgctaaaaat tatttcttag
    34201 ataaaatcaa agacgccgtt taccacgagg atgaaatcaa agtaatcgaa ttggcaggcc
    34261 ttgttgaaat ctcgattcca aaacatgaat taggcgctac attagccgtg taaacaaatt
    34321 ttgaacataa taattaaaga gcgtgggaca aaagtaaaga acacttttgt ctcacgctct
    34381 aaacacgtat aaacggcgaa agcagaagca actccttcgg aaataagctg aaattca
//
LOCUS       DADGHT010000022        33814 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.022, whole genome shotgun sequence.
ACCESSION   DADGHT010000022 DADGHT010000000
VERSION     DADGHT010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33814
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.022"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            298..1959
                     /locus_tag="JX887_000911"
     CDS             298..1959
                     /locus_tag="JX887_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1256919.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2029..2376)
                     /locus_tag="JX887_000912"
     CDS             complement(2029..2376)
                     /locus_tag="JX887_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAX1256920.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2460..3401
                     /locus_tag="JX887_000913"
     CDS             2460..3401
                     /locus_tag="JX887_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1256921.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3402..4445
                     /locus_tag="JX887_000914"
     CDS             3402..4445
                     /locus_tag="JX887_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1256922.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4451..5521
                     /locus_tag="JX887_000915"
     CDS             4451..5521
                     /locus_tag="JX887_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256923.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5511..6464
                     /locus_tag="JX887_000916"
     CDS             5511..6464
                     /locus_tag="JX887_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1256924.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6476..7486
                     /locus_tag="JX887_000917"
     CDS             6476..7486
                     /locus_tag="JX887_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1256925.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7771..8592)
                     /locus_tag="JX887_000918"
     CDS             complement(7771..8592)
                     /locus_tag="JX887_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAX1256926.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8689..8967)
                     /locus_tag="JX887_000919"
     CDS             complement(8689..8967)
                     /locus_tag="JX887_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256927.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9235..11244
                     /gene="metG"
                     /locus_tag="JX887_000920"
     CDS             9235..11244
                     /gene="metG"
                     /locus_tag="JX887_000920"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAX1256928.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11723..12310)
                     /locus_tag="JX887_000921"
     CDS             complement(11723..12310)
                     /locus_tag="JX887_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256929.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12485..13807
                     /locus_tag="JX887_000922"
     CDS             12485..13807
                     /locus_tag="JX887_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1256930.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13962..14738
                     /locus_tag="JX887_000923"
     CDS             13962..14738
                     /locus_tag="JX887_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAX1256931.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14731..15300
                     /gene="rnmV"
                     /locus_tag="JX887_000924"
     CDS             14731..15300
                     /gene="rnmV"
                     /locus_tag="JX887_000924"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAX1256932.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15293..16177
                     /gene="rsmA"
                     /locus_tag="JX887_000925"
     CDS             15293..16177
                     /gene="rsmA"
                     /locus_tag="JX887_000925"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAX1256933.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16628..17257
                     /locus_tag="JX887_000926"
     CDS             16628..17257
                     /locus_tag="JX887_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256934.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17381..18490)
                     /gene="ugpC"
                     /locus_tag="JX887_000927"
     CDS             complement(17381..18490)
                     /gene="ugpC"
                     /locus_tag="JX887_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAX1256935.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18699..19121
                     /gene="mgsA"
                     /locus_tag="JX887_000928"
     CDS             18699..19121
                     /gene="mgsA"
                     /locus_tag="JX887_000928"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAX1256936.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19444..19980
                     /locus_tag="JX887_000929"
     CDS             19444..19980
                     /locus_tag="JX887_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAX1256937.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20020..21783)
                     /locus_tag="JX887_000930"
     CDS             complement(20020..21783)
                     /locus_tag="JX887_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256938.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21786..23501)
                     /locus_tag="JX887_000931"
     CDS             complement(21786..23501)
                     /locus_tag="JX887_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256939.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24280..24504)
                     /locus_tag="JX887_000932"
     CDS             complement(24280..24504)
                     /locus_tag="JX887_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1256940.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24704..27472
                     /locus_tag="JX887_000933"
     CDS             24704..27472
                     /locus_tag="JX887_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1256941.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            27553..27972
                     /locus_tag="JX887_000934"
     CDS             27553..27972
                     /locus_tag="JX887_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAX1256942.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            27984..28454
                     /locus_tag="JX887_000935"
     CDS             27984..28454
                     /locus_tag="JX887_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1256943.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28471..29250
                     /locus_tag="JX887_000936"
     CDS             28471..29250
                     /locus_tag="JX887_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1256944.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29237..30058
                     /locus_tag="JX887_000937"
     CDS             29237..30058
                     /locus_tag="JX887_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAX1256945.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            30075..31124
                     /locus_tag="JX887_000938"
     CDS             30075..31124
                     /locus_tag="JX887_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAX1256946.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            31137..32141
                     /locus_tag="JX887_000939"
     CDS             31137..32141
                     /locus_tag="JX887_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAX1256947.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32774..33793
                     /locus_tag="JX887_000940"
     CDS             32774..33793
                     /locus_tag="JX887_000940"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAX1256948.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT        11041 a         5992 c         6907 g         9874 t
ORIGIN      
        1 cagataaggg actgtgacaa gacttttgtc acagtttctt tttgtttatt cttttttatc
       61 tttgtatggc aataatagac aatataacga aaattattta atggcttttg gaagaccatg
      121 gaaaaccttg tacaaagcta ttttttctga aaaattcctt gaaacctcac gaaaaaatca
      181 ttattttatg aaaaagacaa aaaaaagtgt tgatttttta ataattattc attaaactct
      241 taaacaactt cagaaaatat taattattct gaaaattcca ataaaggggt acgtaaaatg
      301 aaaaagaaat ttacatttgg tttggttgcg gtatgcggcc ttgtacttgc tggatgttat
      361 ggcggcagtt cagccacaag cagtagttca gcaaaaagcg gttcagcaga tggaggaggc
      421 gtatttaact tagtcgtgcc tcaagaaatg cctacagctg acttatcagt tgcaacagat
      481 acaatcagtt ttacagcatt gaataacgtt tatgaaggaa tttaccgtct tgatgaagac
      541 agcaaaccac agccggcagg agctagcgag ttggcagaag tcagtgaaga cggattaact
      601 tacaaaatca aattacgaga agacgcaaaa tggtcaaatg gtgatcctgt tacagcagcg
      661 gattacgttt atggctggca acgaacagta gacccagcta cagcttctga atatgcttac
      721 ctgtatgcgc cagttgaaaa tgcagaagac attacagctg gaaagaaaga taaatcagaa
      781 ctagggatca aagcagttgg tgactatgaa ttagaaatca aattgacgaa acaaacacca
      841 tatttccaat atctgcttgc tttcccatca tttttcccac aaaaacaatc cgtagtggaa
      901 gaaaatgggg atgcctatgc atctgcaagt gataaagctg tttataatgg accattcaca
      961 ttagaagatt ttgatggacc aggaacagat acagaatgga cttataagaa aaatgatcat
     1021 tactgggaca aagatacagt aaaactttct gaaatcaaag tcagtgtagt aaaagaatct
     1081 tctactgcat tgaacttatt caaagatggc caagcagatg acgtgatctt gtctggtgag
     1141 ttagcacagc aaaacgcaaa cgatccagct tatacttctg ttaaagaagc gcggacaagc
     1201 tatatcgaat tcaatcaacg tgaaaagaat tcaccattca acaatgtgaa cctaagaaaa
     1261 gctatttctt attctatcga tcgtgaagct ttagtaaaac aagtactagg tgacggatca
     1321 gttgtctcta caggattgat cccatcagat atggtaaaaa gtccaacaac gaacgaagac
     1381 tttgcaaaag aagctggaaa attagtttct tatgacaaag ataaagcaaa agaatattgg
     1441 gaaaaagcga aaaaagaatt gggcgttgat tctttagaat ttgatttgat ggcttctgat
     1501 gatgattcat cgaaaaaagt aatcgaatat gttcaaaact caatccaaga aaacttggat
     1561 ggcgtaacag tcaaaccaac acctgttcca ttctctgtac gtcttgaccg ctcaacttcg
     1621 ggtgattttg acgcagtact aggcggatgg gctgctgact atgcagaccc aagcagcttt
     1681 actgatttgt ttgtcacagg taattcatac aaccgtggtc gctggagcaa tgcagaatat
     1741 gacgaagcag ttaaagcagc ttcatcaaca gacgctggcg atgaacaagc ccgttgggat
     1801 gatttccaaa aagcaatcaa gatcatctct gatgatatgg gtgtcgttcc ggtgtaccaa
     1861 aaagcagaag gtcacctagt gaatgaaaaa atcaaaggta tcgttcacca tgcggcaggc
     1921 gcttcatggg attacaaatg gacatacgtt gaagaataat cgttaatacc gtgagcatga
     1981 gaaaaaacga ggctgcggca aatgtcgcaa cctcgttctc atattcactt atcctaacaa
     2041 agaaaaaagc atgaaaatag cagaaagagc aattagtatt ccggcaatga tcagccaaaa
     2101 gctgtacata ccgtagctgg cagacgagag cgtggaaaat tctggttttt tctttcggtt
     2161 ccttgttcgt gcaagatgga ccgatcgctg aaaatgatcg aagaaacccg aagaaaagac
     2221 ccataaaaaa ccgccgataa tcagaaacgg caatgaccat aagaatagat cattagataa
     2281 ttgaatgagt gtaaaggaat ggttgatgag attttttatt aaaataacca gaatcagtag
     2341 aaaagctact gcgtagggga tagatttttt tttcatttga ttgctccttt atttttggtt
     2401 cattatctaa taatgtagcg aaacatctgt cagaagtcaa aagctagggg gaaacattag
     2461 tgaatagtta tatcaaatat gtattaaaac gtgtcttttt catgatcatc acgctttggt
     2521 taattgcaac aatcaccttt ttcttgatgc aattgctgcc gggcacgcca tatacgaatc
     2581 aggaacgttt gagtcctgaa acaatcgaga tgctaaataa acaagtcggt ttggataaac
     2641 cagttatcgt acaatatggg atttatcttt ctaatttgct tcaaggagat tttggaattt
     2701 ccttccaatt taaaaaccag ccagtcgcac atttgttagc tggaagaatc ggaccatcct
     2761 tgcagttagg gttacaggca attatctttg gaacagtcct agggacgatt ttaggaacga
     2821 tctctgccat gaagcaaaat acatgggcag atacatcttc tacactcgta gcgatattag
     2881 gtcgttccat tccaaacttt gtatttgctg ttttattaca atatatcttt gcaatcaaat
     2941 tacaagtttt gccaatcgca aaatgggatg gctttgtgta cacaatctta ccaacaattg
     3001 cgttggccat gtcgccgctt gctgactctg ctcggtttat ccgtacggaa atggtggaag
     3061 tactgcatag tgattatgtg gaattagcaa aagcaaaagg attgagccgt tgggaaatcg
     3121 cctttaaaca tggtcttcga aatagtttga ttccattgat gactttatta ggaccgttag
     3181 ctgtagcatt gatgaccgga tcactggtgg tagaaaatat ctttgctatt cctggtatcg
     3241 gggaacaatt cgttaagtca atcacaacaa atgattatcc tacgatcatg gctgtaacga
     3301 tcctttactc atttatgctg atttttgtta ttttgatcgt ggatctattg tacggtctag
     3361 ttgatccaag aattcgtgtt tcagaaggga gccgaggata aatggaaatg ataccaaagc
     3421 gttatgaaac agttgcagat atccctgcgg atgaatttct tccattacaa aaaaataccg
     3481 aagaagaacg tgaacagatt actgcacctt ctttgaattt tatccaagat tcatggcgcc
     3541 gtttaaagaa aaacaaagct gccgttattt caatggtttt actattggtc atcattttga
     3601 tctctgtgat cacaatcttt gtttctcctc atgatccaac tgcccaaaac gtggcttata
     3661 tcaatttgcc tcctcgtatt ccgggaatca atatcgatgg attgaatgga aaagcaatgg
     3721 ttggtggtga acttgttgat aaatatgctc aagcaaacgt cccttcaaac gtaaatttct
     3781 ttttaggaac agacggtttg ggacgtgatg tattaagccg cttatttatg ggaatgagaa
     3841 tctcgttgct gatcgcattt attgctgcat tactagatgt aacgattggt gtagcttacg
     3901 ggttggtttc tggtttgtta ggcggacgtg tcgataacgt gatgcaacgt tttttggaaa
     3961 tcttatcagg aattccaaac ctcgttgtca tgattttgat gttggtcgtt tttgaaccag
     4021 gaattttttc aatcgtggct gctatggcca tcacaaactg gataccaatg gcacgtatcg
     4081 ttcgtgcaca aacaatgaaa ttaaaagatc aagaatatgt tttagctgga ttgacattag
     4141 gtgaatcaag aatgaaaatt gcattcaaac atattttgcc gaatatctct agtgtcatta
     4201 ttattcaaat gatgtttagt attccatctg ctattttctt cgaagccttt ttaagcttta
     4261 tcggtttagg tcttacgcct ccgtcagctt cattaggaac gatgttgagc gaagggtaca
     4321 agacattcct gtatctgcct tatctattat ggattccggc agtaacttta tcggttatca
     4381 tgattggctt taacttactt gctgatggat tgcgtgatgc ctttgatcct aaaatgaaag
     4441 agtgaagacg atgacgaaaa ttttagaagt gaaagactta gaaatctctt ttgatacgta
     4501 tgctggaaag gtacgagcga ttcgcggtgt caattttcat ttgaataaag gagaaacatt
     4561 ggcgatcgtt ggggaatctg gaagtggaaa atcagtgacg accagaagca tcatgcgctt
     4621 gctgtcaagc aacgccaata tagatgctgg tcaaatcctc tttaaaggta acgatatcgt
     4681 tggaaaatca gaaagagaga tgcaaaaaat ccgtggtaaa gaaatagcga tgattttcca
     4741 agatccaatg acctctttag atccgacgat gcccattggg aagcaagtcg ctgagtccct
     4801 tagaaagcat aataaagttt caaaaaaaga gggacaaaaa gctgcattag aattgcttaa
     4861 attagttgga atacccgaag ctgagaaacg tatcaacagt tatccgcatc agttctcagg
     4921 aggtcagcgt caacggatcg tgatcgcgat tgcactggta tgttatccgg aaatcctgat
     4981 tgctgatgaa cctacaacag cgcttgatgt gactattcaa gcacagattt tggagctgct
     5041 gaaagaaatt cagacaaaaa tcgatacatc aattatcttt atcactcatg accttggtgt
     5101 agtagcgaat gtcgctgatc gtgtcgctgt catgtatgga ggaagaatcg ttgaagttgg
     5161 aacatcggaa gaaattttct acaacccgca acatccctat acttggggac tgcttggttc
     5221 aatgccgaca ttagatagtg cgaacgatcg attgtatgct attcctggtt ctccaccgga
     5281 tttattgaac ccgccaaaag gagacgcatt ctatccaaga aatgaattcg cgatgaaaat
     5341 cgatgcagaa caagaaccac cattttttga actatcaaaa acacacaagg cagcaacttg
     5401 gctacttgct ccgcaggcac ccaaagtgac accgccagaa gaaatccaac gtcgctgggc
     5461 tatctttaaa gagaaacaaa aacatactta cggtcaagga ggaattgctg atgccaaata
     5521 aactacttga agttaaagga ttgaaacagt atttcaatgt aggaaaaaag aatgaagtac
     5581 atgctgtaaa tgacatcagc tttcacattt atgaaggaga aacattcggt ttagttggag
     5641 aatctggaag cggaaaatcc actactggcc gtacgatcat tcgcttgaat gaacctactg
     5701 atggtgagat attattcgac ggtcaagata taacgaagat caaagataaa aaaggtttga
     5761 cgaaattccg gcatgatgtt cagatgatct ttcaagatcc atacgcttcg ttgaatcctc
     5821 gtatgaaagt cagagatatc attgccgaag gaattgatgt taatggacta gctaaatcat
     5881 ctgaagagcg tgcaaaaaaa gtcgatgatc tattgagaac tgttggattg aatccaagcc
     5941 acggtactcg ttatcctcat gaattttcag gtgggcaacg ccagcgtatt ggtattgcac
     6001 gagcattggc agtaaaaccg cgttttatca tttgtgatga accaatttct gcactagatg
     6061 tgtcgatcca agcccaagtg gtcaatttgt tgcaagatct ccaaaaagaa catcaattga
     6121 cctatctatt tattgcacat gatttgtcga tggttaaaca tattagtgac cgaatcggtg
     6181 taatgcataa cggcttgtta ttagagatgg gaacaagtga tgaaatctat aatcacggtg
     6241 ttcatcctta tacagaaagt ttgttatctg ctattcctct accagatcca gaccatgaga
     6301 gaaaacgcag aagaatcaaa tatcaacctg aaccagatga cggacaagta cgtcaacttc
     6361 gtgaaatcgc accagaacat tttgtctatg caactgagca ggaagtccca tattacgcaa
     6421 aaaaactaaa acgacaaaag gaatctcttc tggttgctaa ctaggaggga catagatgct
     6481 aaaagctttt aaattccgta tgtatccgac agaagaacaa aaacagcaat tgattcgtac
     6541 ttttggatgt gctcgattta cctataacca tttgctgaaa aagcggcaga aaagttggca
     6601 acaaacagga gtagccaatt tttcgctcac acccgctaca ttaaaaaaag aatacccatt
     6661 cttaaaagaa gtagacagtc ttgctttagc aaatgcacag cttaatttgg atcgggcttt
     6721 tcgcaattat ttcaagggac gtgccagctt cccaaagctt aaaacgaaaa aaagtatgtg
     6781 gcaatcttat acgaccaaca accaaacccg tacgatctat ctggaaaatg gctacttaaa
     6841 gttaccaaaa caaaaagaac taatcaagat aaatcagcat cggccagttg aaggatcgat
     6901 tcgctccgct acgatttctg ctcgatataa tgaagaattt tatgtcgcac tactttgtga
     6961 tgtttcgcca gtaaaaaaag aatctttagc taaatggatc gggatcgcct atcatccgaa
     7021 gacattgatc caaacatctc gacctctaga agtaacttta ccaaaatttc accagacaga
     7081 agaaaagctg caacatgcac agcggaaatt gaatgtgaaa gtccgctccg ctcaccatag
     7141 aaagatcagg ttagatcagg caagcaatta tcagaaacaa aagagaaaag taatggatct
     7201 ttatctgaaa caaaagaacc agcgagaaga ttatcttgaa caattatctg ggaaattggt
     7261 caaacaatat gactacttat ttgtagaatc ttttccaaaa gaagaggcac atgctgattt
     7321 ttctattcac gactggcata aattaataac aaaattgcgt tataagtccc aatggtataa
     7381 taaaaaattt cttttgatca ataccgacgg agcagaagaa agcaattccg taagaaagag
     7441 ccaagtagta gaaaaaatgg gcagacattc ggttatcaag ggataaaaaa tgaatgaaac
     7501 tgataggagc gttagggtta gccttgttaa taaaaagtct taatgacttt tgtttctagg
     7561 aatttttctt ttgaagaaaa gctcactaat tatgacaaac caataaaaca atagcagaaa
     7621 aagttcgtac gagctttttc tgctattgtt aattttttat tcagaaagtt tacgaataca
     7681 tcaaaattct gaaacaaaaa acgtaactca caaagagttg tttttgcgtt ttttcttgaa
     7741 tgattaggtc tgaatctttt gctcacaacc ttattcatgg tgccccggct tgagctgata
     7801 gatttttgaa ggacggccga ttcctacagg acgttcaccg atctcatcga aatattggag
     7861 catagctttc ttaaaattgg aatgatcgat cgttttataa tcgatcccta agaatttagc
     7921 aaatactttt cgagcttccg taatcgtgaa atctttacct aaaacttgta gaacttgcgg
     7981 ctcgtgttcc attttattga ctacacggtt gaatgctttc aagatgattt gactatggtc
     8041 aaaagccaaa gtatctttgc cagaagactc tccagtgact aaatcaagcg agatagccac
     8101 ttctccgcta gataaatgga tcttgttact atgacgttct agtgtgaacc agcgtacttc
     8161 cttggcatca tctccggcga ttagcggttc ttctccaata aaggctaagt agctgactgt
     8221 gacgacccag cctcgcggat ctcgattagg cgtactgaat gtatgcagtt gctcaatatt
     8281 ttcttttgaa ataaccacac cagtttcttc ctttgtttct cttaagacgc tttctccagt
     8341 tgactcatcc ttttggacaa agccaccagg caatgcccat gaatttcgat aaggatgccc
     8401 ttttctttgg atcaacaaaa ctttcagctg atcttcttct ttgttatagc acatcagtac
     8461 gatatcgaca gtcaaagagg gcttgtcata ttctggacgt tcctgttttt gataccagtt
     8521 aagaaattct tcttcacttg ctttatgttc ataatataat ttttcttctt ctttagaagc
     8581 aaaacggttc atctgaccac ctccattgac agtaaaagta ctttttacct tattgtagca
     8641 gactctgaaa aaaaaccaag gatttacttg aaaaatctag gttatcattt aaatatgaaa
     8701 aataaatgga agtatgagat tgaataaaaa gaaaagcaga taaaacggca atactttata
     8761 ccgctcttca cgaatggcaa agaagccaca aataacgata tatacgtcaa tgataaaacg
     8821 caaaatccaa gctgctgtca taaaactgtt caaatgccca tggaggttaa aataaccata
     8881 catacgaata taaaaatagc tgaatattaa atgtgctaat gaaagaaaag caatactaag
     8941 tgtaaaaaaa agatgtttct tctgcatgat tgttccagtc ccttactaag atagatagtc
     9001 tttattatac cacgtgtgag gggagaaata aaaagccgtt ttttagtaga tatgaaacaa
     9061 aacaaaaacc cgcatttatt caacctattc atccttttaa aggatagatt gaacgtagat
     9121 agaagtcgtt tatccagtct ttttcatttt gaaaaaaagc taacagcatg ctttttttat
     9181 ggtatactag caaggaaacg aattcgcatc atgcgataaa ggaggaagag ccccgtggca
     9241 gaaaaggaaa ctttttatat cactacgcca atctattatc caagcggcaa acttcatatc
     9301 ggcaactcgt atactacgat tgcatgtgac gcaattgctc gttataaacg gttgatgggc
     9361 tttgatgtgt tttatctcac tggagtggat gaacatggtc aaaaaatcga aacaaaagca
     9421 gaagaactag gtgtaaaacc gcaagaatat gtagataaaa tggcggctga tgtcaagaaa
     9481 ttatggaaaa cgcttgatat cagttatgat aaattcattc gcacgacaga tgattaccat
     9541 aaagcagctg ttcaaaaaat atttgatcgt ttattagaac agggagatat ttacttaggt
     9601 gaatatgaag gctggtactc tgtttctgac gaagaattct ttacagaaac acaacttgca
     9661 gaagtgtaca aagatgacga aggtaacgtg atcggtggta aagcgccaag tggacacgaa
     9721 gtagaattgg taaaagaaga atcatacttc ttccgcatga gcaaatacgc agaccgtcta
     9781 ttggaatact atgaagaaca tcccgaattc atccagccag aatctcgtaa aaacgaaatg
     9841 atcaacaact ttatcaaacc aggattagag gatcttgcag tttcacgaac aacttttact
     9901 tggggagtac cagtcaagag tgatccgaaa catgtggtgt atgtatggat cgatgcatta
     9961 tccaattata ttactgcact aggatatggc tccgaagatg aaagtctatt cgaaaaatac
    10021 tggcctgcag atgttcagat ggtcggtaaa gaaatcgttc gctttcatac gatctattgg
    10081 ccaatcatgc tgatggccct tgatttgcct ctacctaaaa aagtatttgg gcatggctgg
    10141 ctattgatga aagacggaaa aatgtctaaa tcaaaaggaa atgtcgttta tcctgaaatg
    10201 cttgtggaac gttatggttt agatgcactc cgttattatt tgcttcgtgc tgttccgttt
    10261 gggtcagatg gtgtctttac gccagaagat tttgtttccc gtgtcaatta tgatctggca
    10321 aatgatctag ggaacttatt gaatcgaacg attgctatga tcaacaaata ttgtgatgga
    10381 ctcgttcctg actatgcctc acttgtcact ccatttgata gtgaactgtc tacgacggct
    10441 gctaacgttg tcggacgtta ccatgatgca atggaaaaaa tggaattcaa tacagcattg
    10501 gctgaaatct gggtgctgat ttctcgtgca aacaaataca ttgatgaaac agaaccatgg
    10561 gtattagcaa aagacgaaga aaagaaagct gaattgaata gtgtcatgat ccatttagct
    10621 gaatctttgc gtatcgcagc gatattactt cagccaatca tgacagaaac gccagagaag
    10681 atcttcaatc aactaggatt ggactctgaa acaatgaatc ttgaaggatt acactttggc
    10741 gaatttcctt caggaacaaa agtagttgca aaaggtacac caatcttccc acgtttagat
    10801 atggaagaag aagttgcttt tattcaagaa aaaatgtctg aaggtactca aacaaacgaa
    10861 gatacagtca aatgggatcc agaagaaaca gaacttgttt caacgaaaga aaaacaaatc
    10921 aaatttgatg tatttgaaaa agtagaacta aaagtagcag aagtcatcaa ctgtcaaaaa
    10981 gtagaagggg cagataagtt gctgcaattc cgactagatg ctggagacag ccaagaccgt
    11041 caaatcttgt caggaatcgc tgaattttat cctgatccaa gcgaattgat cgggaaaaaa
    11101 gtcgtcattg tagcaaatct gaaaccacga aagatgcgtg gacaaatcag tcaaggaatg
    11161 atcctttctg cagaagcacc agatggctct ttacaagtaa tcgaagcacc aaaatccatg
    11221 ccaaatggct cagaaatcgc atagaaattc aaagggggta tgacactagt tgtgtcatac
    11281 cccctttttc cgaaatttga gaagcaattt tcgtaaattc cttcttatta cttgaagcca
    11341 atcatataat acagaaacag agaactatcc aaaataaatc ctagaaaaag aagtacgagc
    11401 ttcgctgatt tttgttaatt tagaataata ctaataggaa tcgtaaaaac agaaaaaaag
    11461 cataatgata aagggtcggg cagattttaa ttgattcatc tggtactctt ttttattgtc
    11521 cttacattca taaagtttga atgcaatgac tttattacat ctatatttat atctaacagt
    11581 agcgttgatg tgttaattat aagttctatc actttatgtt caattagttt gtgctcttat
    11641 atgtgtgatt gaaaatatag ataaaaaaac aatcatcggc tttgacttcg atgattgttt
    11701 tctttatttt gtaaaaatcc tatcacttga ttttatggta accttttatt tttgtcttca
    11761 aacggcttgg taagagagca gtaagcagtg caaatgggat cgaaaagaca taccagaaaa
    11821 tcgtacgtcc gataccataa tgttgataga gctttgtcaa catcacgtgt aacaagatca
    11881 accctaaaag caaggagcca gctataaacc aatgattatc ccaatgcatg acttcactaa
    11941 gtgccatcac tccaaaagga tagaaataaa aatagatccc gactaaggtc atccgccagt
    12001 tctttgtaaa tgttccgata ttcaataaaa agaaaatcgc tgaaagcaaa ataccgatag
    12061 gcggaaaaag cccaaccaaa aaggaataca acatccccca caagatcatc acaggacctt
    12121 tgatcaatgc aacgattgcg atgaacaaag tcagcaatat tagtttttgt gataacgttg
    12181 caacagtcat taatccaaat aaaattaatg tgaaccaatg ccaatgggac tgctgttgtt
    12241 ctttacggga aaaatcgacc cggttggata aataatctgc taatttcgga taagaacgct
    12301 taaaatccat aaactgttcc tccttcgtgg aaaaggtagg tttagtatac gaaaaataaa
    12361 aaagaaatac atccgtctta agagggagtt tttcactgaa agtggagaaa aaagaatggt
    12421 aaattaaaat attctcagtt atactgaaaa ttataccaaa tttcaaagaa gaaagaggat
    12481 gggaatgaaa ggcaaactaa aacgagaaat caatctgttt ggcgcattag ctaccgttat
    12541 gggaaccgtg atcggtgcag gcgtcttctt caaaactgct gctgttactg ctagtactca
    12601 gtctacaagt ttgacattgc tagcttggct tttgggtggt ttcttaacga tctgtgctgg
    12661 attgacagtg gctgaattag ctacagcaat cccggaaact ggtggagctg taaaatatat
    12721 tgaagctgcg tatggaaaat tgcccagctt tttattagga tgggcgcaaa gcttgattta
    12781 ctttcctgct aatattgctg cattatcgat tatctttgcg acacaattga cgaacttatt
    12841 acaattatct accgattatc ttttgttgat tgcagtgatc accgctgttt ctgtgacagg
    12901 gttgaatttg ttagggacaa aagtcggtgc ttctgtacaa tcagtgacgt tgattgttaa
    12961 attaatacca attgctgtga ttgtcatatg gggattattg accccaggac aaggaactgt
    13021 ccagttattt ccaatcgaag ctggaaaaga tgttactttt gtcgaaggat tgagcagtgc
    13081 gttgttagca acgttgtttg cttatgacgg ctggttaggt gtcggtgcaa tggcagggga
    13141 aatgaaacgg ccggaaaaag atttgcctaa agcaattatt cttggtttga gttttgtaac
    13201 agtcgtttat ctattgatca attttgtttt tttgaaaact ttgccgattg atcatcttgc
    13261 cggtaatttg aatgcagctt ctgaagcatc agacgtcatt tttggaggaa tcggtggaaa
    13321 gctggtcact attgggatct tgatctcggt atacggtgca ttgaacggtt atacactaac
    13381 tgggatccgc gtgccttatg cgatggcttt agaagacgag ctacctttca gtaaacagct
    13441 gacaaagctt tcaaagaagt ttacggttcc ttatgttcct gcggttttcc agttagcagt
    13501 agcttgtatt atgatgagcc ttggttcttt cgacttttta acagacatgt tgatttttgt
    13561 gatgtggcta ttcagtttac tgatttttat cggtgtcttt attttaagaa aaaaagcgcc
    13621 ggaattgcca cgtccatata aagtaccact ttatccaatc gttccgatta ttgcgattct
    13681 cggtgctatt ttcattttag gtatgacgat gatgacgcaa acgaaattag cattgatcgg
    13741 tataggtgtt accttgatag gtatcccagt ctattatcaa aaaaagaaaa aacgctcaga
    13801 agagtaaaat atttcaacaa cagacagaaa aagtacgaac taggtcctct agatcttcgt
    13861 gctttttcta tttcaataaa acaagttctt ctattttgat ttttgctact tctgcaagta
    13921 gtgcttatgt gctaaagtaa gaatgaaaag gagagataaa catgatattt gattctcata
    13981 cccatttaaa tgctgaacag ttcaatgaag atattccaga aacgattcag cgagcacaag
    14041 aaatgggggt aacgaaaatg gcggtcgtgg gcttcgatac gccaacgatt gaaaagtctt
    14101 tgcaattaag ccatgactat ccaaatatat acagtattat cggctggcat ccgacagagg
    14161 ctggcagtta tacgaaagaa atcgaaaata aattacaaga acaattgact ttaccaaagg
    14221 ttgtagcatt aggggaaatt ggcttggatt atcattggat ggaagacccg aaagaagtcc
    14281 aagataaagt atttcgcaga cagattgcta tcgcaaaaga aatgaaccta ccaatcagta
    14341 ttcatactag agaagcactt gaagacacgt atcaaatcct aaaagaagaa gatgttcgag
    14401 atatcggtgg aatcatgcat agtttcagtg gtgattatga atgggcaaaa cgatttcttg
    14461 acttagggat gcatatttca tttagcggtg tcgtcacttt caaaaaagca ttagacgtcc
    14521 aagaggctgc agcaaatgta ccaatcgaac gattacttgt ggaaacagat gccccttatc
    14581 tggcaccagt tccttttaga ggaaagcgaa atgaaccagg ctatactcgt tatacagtag
    14641 aaaagattgc tgaacttcgg aatcttccga cagaagaagt ggctgcccaa acatggacaa
    14701 atgcgcaccg attatttggt ctaagcgaac atggataaga tgaagatcca agagattata
    14761 gtcgttgaag gaaaagacga tacaagaagg ctgcgggaag tagttgatgc agatacgata
    14821 gaaacaatag ggtctgcaat caatgaagag atcctgatgc aaattgaaca tgcccaagag
    14881 actcgtggag tgatcgtttt taccgatcct gatttttcag gagaaaaaat aagaaaaatc
    14941 attatggaag ctgttcctca ggcaaaacat gcttttttgc cgcgcacaca agctaaacca
    15001 aagaaaaagg gaagccttgg tgtcgagcat gcaagtgatg ctgctatttt agaagcattg
    15061 aaaaaggtcg tgacgccaga catttcccaa acggctgttt ctgaaatcac tagacaagac
    15121 cttttagact atggtttaat agctggggca caagcaaaag aaaaacgaga aaaactaggt
    15181 gacgagttgc gcatcggtta cacgaacggc aaacaattgg aaaaacgttt gaagatgttt
    15241 cgtattacgc cgaaagaact cgcccaagca atgaaaatag tggaggaaca acatgagtga
    15301 atatcgtgaa attgcgacac cctctagaac aaaagagatt ttattgaaac atggtttttc
    15361 atttaaaaaa agtttaggac aaaattttct gactgaacca aatattttaa ggaaaatcgt
    15421 agaaactgcg caaatagatg aacatacgaa cgtgatcgaa gttggaccag gaatcggtgc
    15481 attgacggaa caattagcca agcatgcaaa acaagtcgta gcatttgaga tcgatgatcg
    15541 tttgatccct gtattggctg atacgatgca accctatgac aatgtgacta ttgtacatca
    15601 agatatttta aagaccgatt tgtcaacagc tgttagagaa acatttcatg aggagcttcc
    15661 gttaaaagtc gtagcgaatt taccttacta tattacgaca ccgatcatga tgcattttct
    15721 tgaatcagat ttggttgtgg atgaactagt cgtcatgatg caaaaagaag tagctgatcg
    15781 tatctctgct gaaccaggaa cgaaagctta tggttcatta tcgattgctg ttcaatatta
    15841 tatggaagcc agtttagcat tcatcgtacc aaaaacagta tttgtccctc agccaaatgt
    15901 agattcagcg attttgaaac tgacaagaag agatataccg gcagtcgaag tgacagacga
    15961 aaaagcattt ttccgattga caaaagcggc atttcagcaa agaagaaaaa cgctttggaa
    16021 taacttgcag cattcgtatg gcaaagatga ccagacaaaa gcatggttag caaaaagctt
    16081 ggaaacagct ggaatcgatc caaaacgtcg tggggagact ttgtcattac aagaattcgc
    16141 cgcattaagc aatgcgatgt cagaaaatat gcagtaaaaa aagaggttgt gacagaagtt
    16201 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa acaaaaatag ttcctcatgt
    16261 ttttcgtttg tttgggctta ttaccgcaga tgcaagcttt tgaacaccgt ttaagaaaga
    16321 ggttgtgggc ctgccgttta actctaagtc acaaggaaca atttcaaaaa acagcttctc
    16381 atgtttttga gttagttggt cttattactt gatgcaagct tttgaccact attatgccga
    16441 acaaggagat gtgacacaaa ttttgtcaca tctcctattt ttgtttcttg atcaaaaaat
    16501 tcttatactt gatactcaca ctcattttgt atggatttag aaaagaatat gtgtcttgac
    16561 agttattagt aagtgagtta tactaagtcg acatttatgt gtcaagacat attaggagag
    16621 agaaaaaatg agaaaaaatt cagttcgaaa actaacgatt tctgctttat tgattgggat
    16681 gggggtcatt atcccaatgg tcatgcctaa aatcatgatt ccaccagctt cctttacttt
    16741 ggcgtctcat gtgccattat ttattgcgat gttttttaca ccaggagttg cagtggctgt
    16801 tgcgctaggt acgacatttg gtttcttttt aacaacgccg gttatcatcg cattgcgagc
    16861 attgtcacat cttgtgtttg cgttgattgg ggcttggtac ttgcaaaagc atccgagtat
    16921 cgttttaaaa aatggacagt ttacttttgc taattggcgt ttccaagggt tcaattttgt
    16981 gatcggtgtg attcattctt tagcagaaat gctagtagtc agcatctttt actttattgg
    17041 taatatgcct gaaacatatt attctcaagg atatttttat acagtattca tcttgatggg
    17101 gattggtggg cttatccaca gtttagttga ttataatatt gcttatttta tagcaggaac
    17161 actcagcaaa tattttgata tccccgtatt tacggcagca aaaaaagaaa atcggaaaga
    17221 gtcgattcaa gggtacgcga agaaaacgac atattagaca tgatctctca aaaaaaaaac
    17281 tctcatctag taatggataa taaatcctct aagatgagag ttttttgtcc taaaaagagc
    17341 tgcaccaaca tcttctggca cagctctaac agggggcaat ttatggaagt ttgatgactt
    17401 gttctgtttc tttatcaaag aagtggcctt tgctgatgtt gaaggcaagg tcgactattt
    17461 cgcctggttt atggaaatct cttgcatcta cttttgagat gaactcagta gaaccagttt
    17521 ttgtgtaaag catcgtttca gctccaagta attcggaaac gacaacttct gatttcacta
    17581 cggcttcagg tgaagcttca agggctactt gttcactgtg gatgtcttct ggacgaatac
    17641 cgaagataac ttcttttcct tcataacctt tttcaactaa tactttgttt tttccttcag
    17701 gaatacgaag cttaagccca tgtccatctg tgataacacc atttttcaat gtcacattaa
    17761 agaagttcat ggcaggagat ccaataaagc cggcaacgaa catattgacg ggtgtatcat
    17821 aaacttcttt cggtgtaccg atttgttgga taaatccgtc tttcatgata acgattcggt
    17881 cagccatagt cattgcttct gtctgatcgt gagtaacata gatggtcgtt gtttcaagac
    17941 gctggtgaag tttggcaatc tcagcacgca tggctacacg taatttagca tctaaatttg
    18001 ataatggctc atccattaag aagacttttg catcccgaac gattgcccgt cccaatgcca
    18061 cacgttggcg ttgtccacca gataaagcag ctggttttcg tttcaagtat tctgtcagac
    18121 ctaagatctc tgctgcattg tccacacgtt ttttgatgtc tgctttatca tatttacgta
    18181 atttcaagcc aaaagccata ttatcaaaaa cagtcatatg aggatacaat gcgtagtttt
    18241 ggaaaaccat ggcaatatca cggtctttag gtgccacgtc attcatgact tttccgccga
    18301 tatttagttc tccttcagag atatcttcca gtcccgcgat cattcgcaaa gtagttgact
    18361 ttccacaacc ggaaggacca acaaaaacga taaattcacg gtctttgatt gatagattaa
    18421 aatcagttac agaataattt tctgcattgt catatttttt atatacgttt ttcagagcca
    18481 tttctaccat aatacgttcc acactttctt ttttagtttt attaactatt taaagtataa
    18541 atgaaagcgt taactaactt caatgtcatg ttgaacaaga attttttctt ttttttgtca
    18601 atgtgctagt tttaagcttt aataaatatc cataagaaat aaaaactgat acactggagt
    18661 aaataagtat gttaacaata tcaaaaggag tgtctcttat gaaaatcgct ttgatcgctc
    18721 atgaccgaaa aaaacctatg atggtgaaat tagcaacagc gtataaaaca atattggaaa
    18781 aacatgaact ttttgctacc gggacgactg ggcagaggat cacggaagca accggcttgc
    18841 cgatccatcg gtttaaatcc ggaccgttag gcggggatca gcaaattgga gccatgattt
    18901 cggaggatca gttagatttg gtgatttttc ttcgagaccc gctggctgca cagccccatg
    18961 aaccagatgt aacagcactt atccgtttat ctgatgtcta tgagattccg ttagctacga
    19021 atatcggaac agctgaggtg ctactaagag gactggaagc cggcttccta gattttcgaa
    19081 gaatcgtcca tgaaatagac aagcatccac tttcattttg atggataagc gtatggaaaa
    19141 ataacgttta atgttcgcct atatgtagct ataaaagcta aacaaactga taatatgcga
    19201 tataatacga acgtattgga taatataaac aataatatta gtttttcgta tttgcagtaa
    19261 atgtgaaaat atgctatagt ttctgtggga aaagatccca aaaataatac agagtagaaa
    19321 ataaagcgtt aagtgctaag aggatgggat gttgcctctt ggacgaagga cgtaatgttc
    19381 gcggttttat tttcgcattc gctgcatgat acgatgtagc agctcttaaa ggagatgcta
    19441 aaaatgaaga aacaccggtt agacgcacgt atgattgcta ttatgggctt attgattgca
    19501 ttgatggtca ctttgtcccg actggtagca atcgagaccc catttattaa aatcagtgtc
    19561 acatttattc cacaagtgat catgggcatt ctttttggtc ctttttggtc agggataggc
    19621 gcagttttag ctgatttagt aggaatggcc ctcttctcga aatctgcatt ctttattgga
    19681 tttacattga atgcatttat tgaaggagca atctacggat tctttttcta tcgaaaagag
    19741 atcacttgga aaaatgccat tctggctacg cttagtgtca cgctgatcat caacttattt
    19801 ttgacaccat tatggcttgc gttgatgtac catgtgccat tgttcagctg ggtcgtttgg
    19861 gcgccccgcc tgttaaaaac agtaatatgg ttaccgattc aatcaattgc catttattac
    19921 gtaggacgta gtattcctta caaaaaaatt ttaagaagtt tagcgatcca cgctaaataa
    19981 aaaacaagca gtcttcccat cccagaagac tgcttgtttt tattgtgctg tgaattgtgc
    20041 ttgatagagc cgtcggtaat aaccatcttt ttgaagcagc tcatcatggg tgcccatttc
    20101 gacaatagct ccctgatcca tcactaatat ctggtccgca tttttgattg tggacaggcg
    20161 atgggcaatc acaaaactgg tttttccttc catcattgct aagaaggctt gttggatttt
    20221 tttctctgtc aatgtatcga ctgagctggt agcttcatct aagatcaaca tagggggatt
    20281 actgatcatc gttcgagcaa tcgtcaacag ttggcgttgt ccatctgata tctttaaccc
    20341 ttgaccgcca atcttagtat ctaatttttc cggcaaacgt tctacaaatt catacatata
    20401 agaggctttt agggcatcat tgatttctgc gtcacttgct tccggattcc caaaacgaag
    20461 attttctcgc aatgtactgt caaatagcca agtatcttgt aacaccattc caaaactttt
    20521 acgtaatgta tcacgttgga tagagcggat gtcatggtca tcgactgtaa ttgttccttt
    20581 tgttgtgtca taaaaacgca tcagcaaatt aacaagtgtg gattttccgg cccctgtttt
    20641 tcctactata gcaatggttt gacctggata agcagtaaaa ttgaaatctt cgatcaaacg
    20701 ctgcttgggg tcataagaaa aagaaacatg atcaaaagag acttttcctt tgatattttt
    20761 gggttccaag gcataggcat ctggcaaatc aggcttttct tctggctgat cgatcaaatc
    20821 aaatgctcgt tctagaccag aaaaagcggt ttgcagttgt gtcgtgattc cagaaagttc
    20881 gataaatggt ttagaaaact gacttgagta gatcgtaaag ctggaaatca caccaacagt
    20941 gattgacgaa ccactcttca atgccaatag gccgccaact aaaccaatcg ataaataagc
    21001 aaggtgatct acaaaacgag aagacgggtt tgtcaaggaa gaagaaaatt gtgcccgttg
    21061 tcctttttca tatagatcag catttagcag ttcaaattgc tgttgactag cttcttcttg
    21121 ctgaaaagct ttcacgattt tctggttacc gattcgttcg gtcacaaagc ccgagatatc
    21181 cccaataatc ctttgctgtc tatcgaaatt tgtttgtgaa gcacgagcaa cgatccaact
    21241 cacaaggaaa ataattggtg tagaacaaag aacgaccaat gtcagaagtg gacttagacg
    21301 catcataaaa ataaacgaaa gaatgatgat tgccactcca gaaaataatt gattgaaggc
    21361 cgcagaaatt gcaatggaaa tattgtccat atcatttgta aatcgactga cgatatttcc
    21421 gtgggagttt tgatcataat aacgaagtgg caatcgattc agatgagcaa atgcatcttt
    21481 tcttaatttt gcaacggata agtaagctaa ccgattgctt aacacttgga tgagccattg
    21541 actgactacg ttgattaaaa cgataccacc gaatagaata agtaaatgga acagtcgatt
    21601 gaagcggacc tgtccttctc caatcatttg atcgatactt tgaccaattt gtaacgtcat
    21661 cacaactgtt gcaatcccat tgatgattcc tagtatcaca gctagccaaa tgtcttttgc
    21721 ataggcagta aggtaaggaa tgaatcggcg gagcgtctgc aaggataatt tttttacttt
    21781 cataactatt cttcctcctg tgatgcgacg atttcctgat attctgctga ttgagcaagt
    21841 aattcttcat gggtaccctg agcagcaatc ttaccttgat ccatcactaa gatatgatgt
    21901 gcttcttgaa tagagcggac acgttgggag ataataatca ctgtactgcc aagataagtc
    21961 tgtagcgcct tacgcaaatc caagtctgtt tgataatcca acgcacttaa agagtcatct
    22021 aaaatcagta atgctggctt ggcaatcaaa gctcttgcaa tcgtcagtcg ctgtttttgt
    22081 ccgccagaga aatttttccc attttccatg acttttgtat ctaaaccatt tggaagctga
    22141 cggacaaatt cttctgcctg agcgattttc agagcttccc aacattcttt ttctgtggcg
    22201 tctttcttac cccattgaag gttttcacga atagtcccgg taaatagtac agaagtttgg
    22261 ggaacaagag caatttgctg acggagatga tccagctgcc aagaacgaac atccattccg
    22321 tccattataa ctgtaccgga actgacatca tagaaacgcg gaatcaattg tgtcaaagtc
    22381 gttttcccgc ttccggttgg accaatgatt ccaaggactg tatttcgctt cagctgaaat
    22441 gtaatatttt ggagagaaag accagaatca ggagtataac ggaagtcaac atggtcaaaa
    22501 gcgataattg cttcagaaga aaaatcggga gtagtactga cctcagcttc aagaatcgaa
    22561 ttttctgtgt ctagcacctc tttcacccga tttcctgaag cttcggcacg tgtgaagatc
    22621 acgacgaggt ttgaaacaac gatcagtgcc aaaagcattt gattcatata attgatcaaa
    22681 gcaagaactt gtccttgttg caagctacca atatttactt tgatcccgcc aactgtcagc
    22741 aaacagatga tcccgacatt catgatcaag gttgtagcag gtgataatag ggcagagata
    22801 ttggaaacac gtaaataatt gttcgctaga tcatttgtgc ttttatcgaa cttctctgtt
    22861 tctttttttg tctgcgcaaa tgcgcggatg acacgaacac cgctaagatt ctgactaacg
    22921 tgttcattga gctgatctag tttttcttgc actttttggt agagaggaac ggtttttttg
    22981 atgataaaaa ataaaatgat tgagaaaata ggcaataatg ctaagaaaaa cagacctact
    23041 tcccagtcga tcacaaaagc catgaccact gacccgatac ttaaaaacgg tgctctgatc
    23101 aataaacgaa tgaccattgc taaagctagc tgaagctgat tgatgtcgtt tgtcattcgg
    23161 gtgatcaagg tatctgttcc aaaatgattc aactcgttgt gagagaaagt attgattttt
    23221 ttgattagct gattacgtaa ctctgtacca aatccttgtg aagctactga agcatagtat
    23281 tggcaaatga tagcacaaat cagaccaatc acagacatag cgaccatcca taagcccatt
    23341 tcaatgattt ttcctcggtc attcattttt agtccattat cgatcaagga agccatcatt
    23401 aaaggcagga caagttcgaa gacagcttca agaaatttga agaacgggcc caaaatgatt
    23461 tgcttacgat agtcttttgc ataacgtaat aactgaatca tatgattcct cctattattt
    23521 atttgtccac aattgaaaaa acaagtacta ccacattgta gcttaggaaa tttagaatga
    23581 aaagagaaca agccttttca taaatgaaag ttttattatg aagaagcttt agaaattgaa
    23641 tagactattt tttttaaaaa aaagaaaatg agaaaacatg ccagtctctt cattcatagg
    23701 aacgtctatt ttacttaatt tttctataaa tgaattctgc ataaaaaata tatcaagtaa
    23761 atgtttatag atgaaactct atttacttct tttttaattt gttcttgcaa tcttttttgc
    23821 tacgtaattt ttgtaaaaaa gtgggttgag agaaatctaa ttgattttca aagaaggagt
    23881 atgaaaatga gaaaaatatt tattcgttta ttgtgggtac tatcttagag gaataaataa
    23941 tagtggagaa aactatggtt tggcgcagat tctatcaggt ttgatggaac gaagacaacc
    24001 tcccgacatc aagtcaaaag ccacttgaga ttttgatctg aaaataaaaa aagaaaacaa
    24061 ggtaggaaca tcaatgtttc taccttgttt tcgtaatcaa tgggaaaaaa ctaagagtgg
    24121 tgtacgtaat caataaaaag gatggtgaca acagtacctc tttactctct gaaagcatca
    24181 taactcgttt ttcctcatta tgccaataaa ttgttgttat accacatata aggatttgta
    24241 atagctaaaa acagacagga aagttgaaat ctgtgaatct tattttgtat ggaaggattt
    24301 atagaacgca aaaatcaaga taaagatgaa taaaaatcct gtttcggcta tatattgcgt
    24361 atctacgcca ataaaacgag tttgttctgt catagccata taaagcaaag gcaaaaatac
    24421 aactacagcg agataagatc cgatgatttc tcgaaaagtt ttccaggaag tatgtttcct
    24481 gtttttatat ttatccgatt tcattgaata gtcatagcct ccttattctt tcatatgttg
    24541 aaattccagt ataaaaactg gaaggaactg tacgtttttt agaataaaaa ttataaggga
    24601 taagtaggct gctgtctata ataagatata tttttcaatt ctttattaaa gattttattg
    24661 acaaaatgaa tccgttttct atgatggagg aggggtgaat aagttgttga agaaggaaat
    24721 tttatgttac ttagagaacc agacagcctt tttcgattta gaacatatga acgaggtctt
    24781 tacagcacaa aggttagctg atcattttgg ggtaaaaaga aacacagtca gtcattattt
    24841 gaaccagtta aatgatgagc aactactagt caaaatcaat tctcgaccag tgatttattt
    24901 ccacaaagaa gcttttgaaa aacaattttt taagttacgc acgaattttt atttttctat
    24961 cgatgatctc aaagaggaac agcctttttt cgcgcaacca aaagacttat tctcttttat
    25021 gatcggatac gacgccagtt tgaaagaaag tatcgaacaa atcaaaacag ctctttacta
    25081 tccagatggc ggattaccac ttttgattac aggcgaaagt ggcacaggta aaagttattt
    25141 agttaatttg gtctatcagt attgtctgct tcatgatctg ctagaagatt ctgcaccatt
    25201 catcactttt aattgtgcac aatatgcaga taatcctgaa cttttgacta gcaatttgtt
    25261 tggacatgtt aagggagcgt acactggtgc agaagaaaat aaaaaagggg cttttgaagc
    25321 agcagatggt gggatcttgt ttttagacga ggtacatcgc ttaacaccag aaggtcagga
    25381 aaaactgttc acctatcttg atcaaggtgt gatttatcgt atgggagaac ctaatttgtc
    25441 acgccggatc aaaacacgtc tcttttttgc tacgactgaa gagattacta gtcatttctt
    25501 aacaactttc attcgaagaa tacctatccg aatcgaacta cctgcactta atcagcgtag
    25561 tcgtaatgaa cggctagaac tgatttactc tttttttctc gaagaacaaa gaaaaatggg
    25621 gagccctttg tcagtcagtg gaccagcttt gtcactttta acaagtcaga aattatccgg
    25681 aaacatagga gagctgaaaa atatcgtcaa agtttcagca gcaaaagcat atgctgaaca
    25741 gcgtgaacag cctgaaatcc atgtcacgat ccatcatttg caaaaagaac tacttgcgca
    25801 gcctattact aaaaatacag cacagcaagg aatctatatt acgcaagacc agaccttaga
    25861 gcaattaatg gagaagcaac agcccgaaca gcagcgaatc gttaaaagtt ttgagcaaat
    25921 cctaattgat ttcaagaaaa ataactgtct gctatattct tgcgaaggaa aattaaagca
    25981 agaagtgatt caattatttg attttttgct gtttgagacc agtagacaag aaaaacacga
    26041 gctgctggtt tattggacac aatctatccg agagaccttt cgacaaatgg aaactgccta
    26101 tcaaatcaaa ttcgatggaa acagtgtcta tgccttgagt tactatctct atcagcgaag
    26161 cactatcaaa tggttaccgg aagaacatga tattatccaa ctaatcaaag aattagaaca
    26221 acaagtttct cagtcttatc catctagtta tcactatgtc caacgaattc tggaattaag
    26281 taagatcaaa ttagatattg aagacacaag tatggatcgg attttactga cgatctatct
    26341 aaaaaaagcg aaatggtcaa aagaaaaacg actgccaaaa gcgatgattg ctgctcacgg
    26401 ttatgcaact gctagcagta tggcaaatgt agtaaatcgt ttattacaag aggatctatt
    26461 tgaatcattt gatatgccac tagatgtcac accacagcag attgcttcag aaatccttga
    26521 ttattgcgaa aacagcgatg tttcaaatgg attgatcata ttagtagaca tgggatctct
    26581 gaaagaaatc catcagtttt ttaaaaaaca gttatccgta ccgcttttga ttttgaataa
    26641 tgtgacgaca cctttagcaa tcacagtagg ggaatgcctg caaaaaaatg tatcattaga
    26701 agagatagca gaagagactg ttcgacagat ccagccagaa tggcgactgc tctatccaga
    26761 ggaaaacaaa cccaaagcac tcattactac ttgcttcact ggaatcggta cggcggtcca
    26821 cttaagtgaa ctgctagaaa aaagcttacc tacggcttgt cagttgaaaa tcatcccata
    26881 tgaatatcag caattaaaag ataagaaaaa cagtgaccca ttattttcca tatacgaagt
    26941 cgtaggaatg attggcacca cagatcctga tatcaccaat atcgactatc tttcattaga
    27001 agacctcatc tcgggggaaa agatgtctgt actagctgaa tggttggaca ctactatgaa
    27061 tgcttcagag aaggaaatat tcaatcagcg catcattcgt aatttttcat tggaaaaagt
    27121 actggattcc gtgactattc tagatacaga gaaggtgatg ggagaaatcg atcattttat
    27181 gagagaatta gaggtgcagt tgaatcgaag catcagcaat cccaaaaaat tagcgttgta
    27241 tgtccatgtg agctgtctca ttgaacgatt gatccgacaa atgccaatcg aaacctatca
    27301 aggattagag aaatggaagc agtgtcaaaa agaagggtta tctgctatta aatctgcgtt
    27361 tagtgtcatt gaagagcatt atagtgtcat gatccccaat tctgagattg cctatatcta
    27421 tgatattttg agtgaagata cagagtttct ctcgatagaa gaagaatttt gaacataagc
    27481 aagttgttgc cactaatttt ggcatgcaac ttgctttttt agtatgtgta agtgaaaaga
    27541 ggagatgaaa aagtggatag agaaattatc ttagcttccc atggaaaatt tgcttcaggg
    27601 atattagatt cattagagct gatctatggg aaaaatcatt ctattactgt attcgattgc
    27661 tatactgatg agaattttga tttagcggaa acagtaaggc agctttttat gaggtacaaa
    27721 gataaagaaa tcattgttct gacggatctt tttggcggaa gtgtcaacaa cgaattctta
    27781 caatatatca atcgggatca tgtctatctc gttgccggat tgaatttgcc actattgatt
    27841 gagctagtat ctcggttgga cgctgaagta gagacaactg ttttgatcca gcaggtgcta
    27901 actgattcaa aaaaaatgat ccagttttgt aacgagcggc tcaatcagaa aatagaagaa
    27961 gacgaatttt aggaggaaga aaaatgattg tattgacaag agtcgaccat cggttattac
    28021 acggacaagt agctttttca tggacacaaa caataggcgc agactgtatt ttgattgcta
    28081 atgatgatgt acctacgaat gagatacgaa agacaacgat caaattagcc aagccacaag
    28141 gagtcaaact agtgatcaaa tcaattgatg actcgattgc cgcgttgaaa agcggggtga
    28201 cagataaata taagttattc atcgtagtgg aatcgatcga ggatgcatat aagctggcag
    28261 aagcgtatcc agaaatcaaa accatcaact taggagggat caaggcaaaa cctggtactc
    28321 gcagcatcgg aaaagcggta aatattttac cagaagagga ggaacgcttg aaacgattaa
    28381 ttgacaaaca aatagaagta gaaatccgtc aagtaccagc agataaaaaa gtggatgtaa
    28441 gagaagtttt gtaagaaagg aagaacctca atgattgtac aagcagtctt attaggaatt
    28501 gttgcatttg tcgcacaatc agaatatgca ctagggacat cgttgctttc tcgtccgatt
    28561 gtgacggggc tgtttacagg aatcgtgtta ggtgatgtaa aaactgggat cattatgggc
    28621 gcaactttag agttagcatt tatcggatcg ttctcagtag gtgcttcgat tccacctgat
    28681 gttgtgaccg gtgggatttt agggacggct tttgctatta cagctggagc cggtacagaa
    28741 accgcgcttt tactaggttt gccgattgct acgttgacat tgatattgaa aaatatttac
    28801 ttagggcttt tgattccaat tatgaaccat aaagcagaca attatgcaga agaaggaaat
    28861 tataaaggag tcgagcatat gcacttgctt gccggtatcg gtctttcctt gatgcttggt
    28921 gttgtggtaa tggtttctta tatggtggga agcaatacga tcggaaatct attaaatatg
    28981 attcctgact tcgttcaaaa ggggttgtca gtagctacag ggttgattcc agctcttggt
    29041 tttgcgatgc ttgctcgttt gctgatcaac aaacaagttg caccatattt tttcttaggt
    29101 tttgctatag cttcttactt agagattcct gtgaccggag tagctatttt tggtgcgatt
    29161 ttagcagttg tggtagtcaa tattatgaat gtccgtcaac taccacttca aacaactgca
    29221 ggggaggtag aagaagatga agaattctga gatcaaaaac agcaaaataa cgaaaaaaga
    29281 gctaaatcac gtattttggc gttcttttca aatggagttt tcttggaatt atgaacgtca
    29341 gatgaatatg gcttatgttt atgcaatgat tccgattttg aaaaagttat atcagtcgaa
    29401 agaagaaatg gcagcagctt tgaaacggca tctagagttt tttaacacga ccccacatat
    29461 cgttacactg attttaggaa tcacggctgc aatggaggaa gaaaataagg atgatcctga
    29521 atttgatgtg actgcgatcg atagtatcaa aacatctttg atgggacctc ttgcagggtt
    29581 aggagattct ttcttttggg gaactttgcg attgattgcc acaggtgtgg gtacctcttt
    29641 agccatgcaa ggaaatattt taggccctat cttgttcatt ttgattttca atattccgca
    29701 cattctgttt cgctatctag caacaggttg gggatatcgc ttaggaacgg gttttttgaa
    29761 aaagatccag gcaaacggta tgatggaaag tttgacatta ggcgcgtcta ttattggact
    29821 gatggtcgtt ggagcaatga ctgccacgat gatcaccatc aatattcctt taaaaatcgg
    29881 ttcaggagaa aatgctgtga ctgttcaaag tatttttgat gatatcgttc caaatatctt
    29941 atgtcttgga gcatttggca tagtgtttta tctattgaag aaagaagtga aaccattaac
    30001 gatcttgatc ggactagctt tctttggaat ttttggttcg tggataggga ttttttaaaa
    30061 aaggagcaga gaaaatgttt acgatgcaag attatatcta tgaagaaaag gaagtactaa
    30121 gtacgatctt gaaaaagaat gatttttcga caagagaaca tatgaaaaaa acagtgaatt
    30181 tactgatctt agcaacgggt tcatcttata acgcttgttt agcagcgaag ccagcattgg
    30241 aatcttatgg tgatcttact gtcgatattc aagaaccttt ttattttttc aattatggaa
    30301 aactttctcc ttcaatcgat actgtgattg ctgtgtcaca aagcgggaaa agtgcttcta
    30361 ctgttgaagc agtaaaaatg atacaaaaac aagggttacc tgttgttgct atcacaaatg
    30421 acgtgcaaag tccacttgct ttagaagctg cacaaattat tgatttaggt gccggggtag
    30481 aatcagtagg cttcgttaca aaaggctatt ctgcgactgt tttacagtta ctactcttag
    30541 ggataggaat tggaataagt aaaaataaaa tcagcaaaaa aatagaacaa gactacatgc
    30601 aacagttgcg caaaataatc aaccatttac cagcgattat tcaaaaaacg gaagaatttt
    30661 ttgatggata tcaaagttta tttcgtttag cacagcgttt cgtcaccatt ggatatggtc
    30721 caaactgggg aacagctaaa gaagcagaga cgaaattgac tgaaacaatc cgcgttccgt
    30781 cacaaggatt tgagttagaa gcttatatgc acggcccata cctggaggca gatgcttcgc
    30841 atttgctatt ctttattgaa ggggaaagtg taaataagga acgttcgcaa aagttgcaaa
    30901 gatatatgag tcggtacgtt ggagagactc tcaccattac cacaaaaaaa gcaagaaacg
    30961 agaaaacact tggattagca atagaatgtg atgaatatct gtctgtatta gcgcttgtcg
    31021 ttccgtttca actattcgct tataaaaccg cagtagctaa aggtattgac ttgaacaaaa
    31081 agatttttga agactttgat acagtcttga aaagtaaatt ataagaggtg gaaatcatgc
    31141 tgaaattcaa tgaagaagaa caaatcaaag caataaaagg cgcactagct ttacgtccgc
    31201 aagtagaaga aatcatcgat aaactttatg cggaaaaatt tgacgctgtc tattatctag
    31261 gaatcggtgg aacgtatgct tcctcgatgc aagctgtcac ttatatgaat gggaaaagca
    31321 acttgcctgt ctttgtacag catgctgcag aatattacac tactggaaac aaaagattaa
    31381 caaaagattc tatcgttatt ttgtcctctg ttaccggtac aactcaagaa gtagtgaaag
    31441 cagtagaaca aatcaagaaa gtaggagcga cactgattgg atttatcgat aaagcgaaca
    31501 gtaagttgtc tcagctatgc gattttgtgg tcacttatcc agctcctgga acagaacaaa
    31561 tcaaattttt tatggcagca gatcgattga tgtatttgaa tggagaattc gaagcttatt
    31621 cagaatacta tgaacagctc gaacgttatt taccaacagg gttagtggaa gcagagaaaa
    31681 aagcagatgc atttggctta tcatttgcag aaaaacatcg acgtgatagt atgcattatt
    31741 ttattggagc agggaatcaa tggggagctg tttattcata tgccatgtgt tactgggaag
    31801 aacaaagctg gcttccatcg aaatctatcc atgctgccga gtttcttcac gggacgttag
    31861 agatcgtaga agaaacaacc ccagtcacat tatttttagg cgaagatgaa cagagagtgt
    31921 tatctgaacg tgtggctaaa cttttgccaa aaatttgcag caattataca ttgatagaca
    31981 caaaagacta tccagtagaa ggtatcagtg aaaaatatcg cggacgtgtt ttgtctttct
    32041 tattgatgca tgtagtgaca caacgcatcg atgctcatgt ggagcagttg aactgccatc
    32101 cattagagat acgccgctac tatcgtcagt ttgattatta ggatagactg gataaaaaga
    32161 atataaaaaa taaagagagc agcgataact gctcccttta tttttttaaa atattggcat
    32221 caattacgtt ataaaacaca ttttttgcat tatctacagt tcaacttata atctgtttaa
    32281 tgggacatgt gggtgccaac cattttttgt tatgcaatag tactatttag ttgttgcatg
    32341 gatccgtagt aaaagtccaa gtacaacgag ttgcgccagt ttacatagcg ttttgtatcc
    32401 agaatgttga ctaaaacaaa agttcctatg tcaaccgtca acagagacaa tctgtccgtt
    32461 gcaggacctg acagatttag aaatgttcaa tctgtctctt atgtatttta aatcaatact
    32521 cactaggaga agtttcctaa cctcctaata gtaatgctgg tagtaacatt gtcaaaactg
    32581 cttcctctta ggaacaagca aagcataacg agtgtaaaaa taaaatgtag actattgtaa
    32641 catatcattg attatttcaa gtaaaaacga taaaagaagt aaacaaacac ttaaaaacaa
    32701 tggaaattag tcccaacttt aagaaatgta tactataatg gaaattatca attatttatt
    32761 tggaggaata tccatgaaac aaaaaatcgc agttcttggt cctggatctt ggggcactgc
    32821 tttagcacaa acattggcag aaaacgggca tgatgtccgt atttggggaa atgtacctga
    32881 acagattgat gaaatcaata agtatcatac aaatcagcat tttttacctg atttgacgat
    32941 cccagaatcg attatcggat ataaagaatt ggcagaagca gtggataacg cagatgctat
    33001 tttatttgtt gttccaacaa aagcgattcg ttcagtcgca caggaactta ttggtaaaat
    33061 gaatactaag ccaatcatta tacatgcaag taaaggacta gaacaagata cgcataaacg
    33121 aatctcagaa gttttggctg aagaaattcc agaagaaaaa agacaggcaa ttgttgtatt
    33181 atctggtcct agccatgctg aggaagtggc agtacatgat atcacaacaa ttacagctgc
    33241 aagtattgat caaaaagcag cagcctatgt acaaaaactg ttcatgaatg attatttcag
    33301 gatttataca aataatgatg tgattggcgt agaaactggt gcagcactga aaaatatcat
    33361 tgcaattggt gccggcgcta tccatggatt aggattcgga gatgatgcaa aagcagcaat
    33421 catgactcga ggattggcag aaatcagccg tcttggtgtc gcgatgggtg ccaatcctct
    33481 gacatttatc ggtttgagtg gtgtggggga cttgatcgtt acttgtacaa gtgttcattc
    33541 tcgcaattgg cgtgccggta acttgttagg acagggacat aagctggaag aagttctaga
    33601 aaacatggga atggtcgttg agggtgtggc aacgacaaaa gcagcagtag agctagctca
    33661 acagctaggt gttgagatgc caattactca aacaatctat aatgttttgt ataatggaga
    33721 agatatcaaa aaagcagcaa aagaaatcat gttacgtgac ggaaaaatgg agaatgaatt
    33781 ttctcttcgt taaatagatg atcaatagtt aatc
//
LOCUS       DADGHT010000023        33256 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.023, whole genome shotgun sequence.
ACCESSION   DADGHT010000023 DADGHT010000000
VERSION     DADGHT010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.023"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(41..229)
                     /locus_tag="JX887_000941"
     CDS             complement(41..229)
                     /locus_tag="JX887_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAX1256949.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="JX887_000942"
     CDS             499..861
                     /locus_tag="JX887_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAX1256950.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="JX887_000943"
     CDS             913..2595
                     /locus_tag="JX887_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAX1256951.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="JX887_000944"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="JX887_000944"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAX1256952.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="JX887_000945"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="JX887_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAX1256953.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="JX887_000946"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="JX887_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAX1256954.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6430..7434
                     /locus_tag="JX887_000947"
     CDS             6430..7434
                     /locus_tag="JX887_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256955.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7435..8379
                     /locus_tag="JX887_000948"
     CDS             7435..8379
                     /locus_tag="JX887_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1256956.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8379..9341
                     /locus_tag="JX887_000949"
     CDS             8379..9341
                     /locus_tag="JX887_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1256957.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9368..10282
                     /locus_tag="JX887_000950"
     CDS             9368..10282
                     /locus_tag="JX887_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1256958.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10308..12089
                     /locus_tag="JX887_000951"
     CDS             10308..12089
                     /locus_tag="JX887_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1256959.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12437..13123
                     /locus_tag="JX887_000952"
     CDS             12437..13123
                     /locus_tag="JX887_000952"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAX1256960.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13143..16724
                     /gene="smc"
                     /locus_tag="JX887_000953"
     CDS             13143..16724
                     /gene="smc"
                     /locus_tag="JX887_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAX1256961.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16733..17542
                     /locus_tag="JX887_000954"
     CDS             16733..17542
                     /locus_tag="JX887_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1256962.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17553..18551
                     /gene="ftsY"
                     /locus_tag="JX887_000955"
     CDS             17553..18551
                     /gene="ftsY"
                     /locus_tag="JX887_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAX1256963.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18738..21005
                     /gene="gshAB"
                     /locus_tag="JX887_000956"
     CDS             18738..21005
                     /gene="gshAB"
                     /locus_tag="JX887_000956"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAX1256964.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21094..21546)
                     /locus_tag="JX887_000957"
     CDS             complement(21094..21546)
                     /locus_tag="JX887_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAX1256965.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21696..22646
                     /locus_tag="JX887_000958"
     CDS             21696..22646
                     /locus_tag="JX887_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAX1256966.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22639..23598
                     /locus_tag="JX887_000959"
     CDS             22639..23598
                     /locus_tag="JX887_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAX1256967.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23595..24350
                     /locus_tag="JX887_000960"
     CDS             23595..24350
                     /locus_tag="JX887_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1256968.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24373..25326
                     /locus_tag="JX887_000961"
     CDS             24373..25326
                     /locus_tag="JX887_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1256969.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25970..26266)
                     /locus_tag="JX887_000962"
     CDS             complement(25970..26266)
                     /locus_tag="JX887_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAX1256970.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26621..26977
                     /locus_tag="JX887_000963"
     CDS             26621..26977
                     /locus_tag="JX887_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAX1256971.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26987..27886
                     /locus_tag="JX887_000964"
     CDS             26987..27886
                     /locus_tag="JX887_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAX1256972.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28403..29134
                     /locus_tag="JX887_000965"
     CDS             28403..29134
                     /locus_tag="JX887_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAX1256973.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29279..31306
                     /locus_tag="JX887_000966"
     CDS             29279..31306
                     /locus_tag="JX887_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAX1256974.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31414..32511
                     /locus_tag="JX887_000967"
     CDS             31414..32511
                     /locus_tag="JX887_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAX1256975.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32818..>33256
                     /locus_tag="JX887_000968"
     CDS             32818..>33256
                     /locus_tag="JX887_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAX1256976.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEK"
BASE COUNT        11135 a         5762 c         7121 g         9238 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag taaagcgatt
     6301 ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg ttataaaacg
     6361 ctttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga agcagagagg
     6421 ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac aggattccga
     6481 ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga caaaaacgag
     6541 attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac tacgattatg
     6601 ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa cgatctgaat
     6661 ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat cggaatgatt
     6721 ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca gatcaaagaa
     6781 ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc actagaattg
     6841 ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc ccatgaacta
     6901 tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa acctccaatc
     6961 gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca gattcttgat
     7021 ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac tcatgactta
     7081 ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca gttcgttgaa
     7141 gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg ctctttactg
     7201 aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga aggtgtcgtt
     7261 ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat tccatggata
     7321 ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa ccacttggta
     7381 cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt gtagatgaca
     7441 gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg attcttcaat
     7501 cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga aaaaggaaag
     7561 acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa agccgttgtg
     7621 ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt aacgaagcga
     7681 agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca agattcaatg
     7741 tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat ccgaaatttt
     7801 gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga tatcgttggg
     7861 atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca acgtcaacgt
     7921 ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga tgaacctgta
     7981 tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg aatccagcaa
     8041 gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa acacatgtgc
     8101 gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag agaagacatt
     8161 tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc gcaaatcgat
     8221 gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga gtatatccaa
     8281 aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac gatcacaact
     8341 acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg attctgcgac
     8401 gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc ttattagccc
     8461 aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat ccggcagtga
     8521 tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag tacttccgtt
     8581 ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa cgctctgttg
     8641 ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg acagttgtcc
     8701 ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa aattcaatct
     8761 tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta tttatcttcg
     8821 gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca agtggatcac
     8881 aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg aaatatattc
     8941 tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa tatctgcgaa
     9001 gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc aaaggggtac
     9061 cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg atggcttctc
     9121 aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa aagatttttg
     9181 gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac tataccgtga
     9241 tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta ctttcagata
     9301 tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca gaaaggagaa
     9361 tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc ctatggggat
     9421 acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat taggtttgct
     9481 agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag acaaagtgat
     9541 gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac aaggacaaaa
     9601 gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga tcataggtgc
     9661 tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca tcggggttgg
     9721 attagggatc atctctggct actacggagg gatcattgac aacatcttga tgcggatcgt
     9781 tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat cgattatttc
     9841 cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg tagctaaagc
     9901 ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca gtgcctcaaa
     9961 aacaatggga accaatgatt ttaaaatcat gttccgcgaa atcatgccga atctaagttc
    10021 attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg agacaacttt
    10081 gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat tgatcggtta
    10141 tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg catcaatcct
    10201 tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc gttctgcaga
    10261 tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg aagaaaacga
    10321 tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg ggcggaggta
    10381 cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa ttaacttttc
    10441 caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa gctgcggtcg
    10501 caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat tcatatgatg
    10561 cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat ttcagaatca
    10621 cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg acaatcaaag
    10681 taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat gtgattttcc
    10741 cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac actttccgta
    10801 acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc ggaatcaaaa
    10861 aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc atgcttcaat
    10921 cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt gtagcaatca
    10981 aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc ccttattaca
    11041 tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac tactggaatg
    11101 gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt gcaactgaag
    11161 cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact tacgatacct
    11221 ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat acttatctag
    11281 gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat ccagattcaa
    11341 aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat aatgcagtag
    11401 gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct ccagtattcc
    11461 agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa gcgaaaaaac
    11521 tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa gacaaagatg
    11581 gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg caaccattgg
    11641 cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac acaacaggtc
    11701 gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct gaaattgatg
    11761 tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta tggggaccaa
    11821 atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg atcaacgata
    11881 tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa aaatggcaac
    11941 aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa gtattgccag
    12001 tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca tgggcaaatg
    12061 tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa gggcgatgtc
    12121 ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc aaggcgctga
    12181 tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt aagtcaaatt
    12241 tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg aaactaaacg
    12301 aatttttcac aacttctcgt caatcactag gattattaaa gctttactta ccttttgacc
    12361 gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa aaatatccat
    12421 aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa actataacat
    12481 cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct atgtgaatga
    12541 gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag atgccgtttt
    12601 agaactgatg gtttctcagt atttattccg tttatatcct catttgccag aaggaaaatt
    12661 gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg ccaaagaatg
    12721 tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag gacgtacgcg
    12781 accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc ttgaccaggg
    12841 attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca aagcaggtgc
    12901 tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa aatcaggtga
    12961 tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac gagtattttg
    13021 gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat cgaaaaaatt
    13081 agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag tgagggaaag
    13141 ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac aagacagtca
    13201 ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga aaaagcaata
    13261 ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg cgaggcggaa
    13321 aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat attgcagaag
    13381 tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat gagatcagtg
    13441 taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa caaagctgca
    13501 gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa tcgttctcaa
    13561 tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac cgtcgtggga
    13621 tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa gcagaacaga
    13681 agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac gaattggaag
    13741 aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta cggctaaaag
    13801 aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca gcaaaaaaag
    13861 attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc aaactatctg
    13921 agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat gcgcaagccg
    13981 atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa ctgaagcaga
    14041 cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa agctcgcaag
    14101 aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa aagcttcaag
    14161 aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct gaagcaaatc
    14221 tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa ttattggcag
    14281 aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga aacgaactga
    14341 agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg ttagccaagc
    14401 aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa ttgacacaaa
    14461 agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa atgatccaac
    14521 aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg tatcaattaa
    14581 tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc caagaaaact
    14641 attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag ctttcgggta
    14701 ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta gctatcgaag
    14761 cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat gctcggcaag
    14821 ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca ctgacgacaa
    14881 tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta gaagggttta
    14941 tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg gttcaaaacc
    15001 tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc gcgcaaacga
    15061 tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc ggaggatcca
    15121 tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa aatcaagaat
    15181 tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca caagaaaaaa
    15241 aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa gttttgcgta
    15301 cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta caaaacatca
    15361 taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag acacgtgaac
    15421 tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac aaacaaacag
    15481 atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt caagaaagcg
    15541 accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa caagcagatc
    15601 ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt gcccgagtcc
    15661 aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg acattgacag
    15721 cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt aacgaattat
    15781 ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag cgagatagaa
    15841 ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt gagcaaaaag
    15901 cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa atgattttag
    15961 ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa gcttcccaag
    16021 actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc ttaaaagaac
    16081 agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa caagtcagtg
    16141 aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa aaccaattgt
    16201 ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa gtatttgaag
    16261 ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt aaagctgaat
    16321 tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa gtacaacctc
    16381 ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca cttacagcca
    16441 tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc ttagatgagg
    16501 tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg agcgatttcc
    16561 aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc gcagcagatg
    16621 tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct gtacggatgg
    16681 aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga aaatgatcaa
    16741 attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga tttcagatga
    16801 gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc tatgtacagg
    16861 acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag atgaaggtga
    16921 ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg aaatcatgga
    16981 aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc agcaattgga
    17041 tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg ccccaaggaa
    17101 gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg atataagcga
    17161 tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag aagaattaga
    17221 tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca tcaaaacaag
    17281 aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta tttctttatt
    17341 ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg aggaaaatga
    17401 tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg tgcctttcgt
    17461 caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag ccaaagtgat
    17521 ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa atcaagcgtg
    17581 cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac gacaagggtt
    17641 tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc aattttcgaa
    17701 cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca gatgtaggtt
    17761 ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc agaaatgcga
    17821 aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc tatgaagcgg
    17881 aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca gttattttgt
    17941 ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc catcagttca
    18001 aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct ggagcaatcg
    18061 accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc aatgcaggag
    18121 gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag caggcagatg
    18181 ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg aacgaattag
    18241 aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa acacttcttg
    18301 tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc aaagaaacaa
    18361 cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc ggtatcgtac
    18421 ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt gaaggaatcg
    18481 atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa ggattactaa
    18541 aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag ctccttgttt
    18601 gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac ttatttgtaa
    18661 gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt agattcatat
    18721 gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc aatgcgcgcc
    18781 cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt gatcttgcag
    18841 gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat cacccctata
    18901 tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc gattctattc
    18961 ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct ataccgaaag
    19021 aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac gaagagatca
    19081 ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta gcaaaaaaat
    19141 acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt ggcgatgagt
    19201 tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa ttcaaaacag
    19261 aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc acttatttat
    19321 tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat ccgcaagaac
    19381 ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat gtgaaagttt
    19441 cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa gaagggaaac
    19501 tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag aaagtcgcag
    19561 atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg aatccttatg
    19621 caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg atgtacatgt
    19681 tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg actcgaaata
    19741 acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa ggtagagaaa
    19801 ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct ctttatttag
    19861 tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg aaactctatc
    19921 aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat caatattata
    19981 aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa ctttctactc
    20041 agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta gatgagtcgg
    20101 atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat gcaaacatga
    20161 caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta acgaaaaaag
    20221 tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc atggaagaag
    20281 cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct aaatcaacca
    20341 attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat tatcaagcag
    20401 gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt atgccgggaa
    20461 cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg cgagtccctg
    20521 ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa aaaaatagtg
    20581 accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta ggtgaattag
    20641 aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa gccaatcaaa
    20701 ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc gatatgactg
    20761 atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca ctaggagcta
    20821 agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca actgataaaa
    20881 aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat gtttatcctt
    20941 ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat cctgaagtat
    21001 tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat caaaagcttt
    21061 ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc agaagctttt
    21121 tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt attttttttc
    21181 gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc cgaattcctc
    21241 aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt tcgttgctag
    21301 ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta tggaagcatc
    21361 tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga tcatttcagc
    21421 aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat gctgttcttc
    21481 agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta catcatcttg
    21541 tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag catattccca
    21601 ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac ttaaaataag
    21661 aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga ctagtagcat
    21721 tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta caattgtcag
    21781 aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt ttgccacgaa
    21841 cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc atgcaacatt
    21901 tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt gcgcgtttag
    21961 gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga tccttgacag
    22021 cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga ttgttcctcc
    22081 agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc attggttcag
    22141 ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca tggcttcaag
    22201 ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt gttccattgt
    22261 tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc gaatcgtttg
    22321 cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc ttagtatcat
    22381 tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga gtgatcattc
    22441 cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc gtaactgctt
    22501 tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg atttttcctt
    22561 atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc ctttatcttc
    22621 tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg tatgcttgtt
    22681 cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa ctggcatttt
    22741 gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct agctgtcagc
    22801 agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc ttcagtattg
    22861 ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat cggaggagtg
    22921 acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct gatggtcggg
    22981 ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct ttttttatta
    23041 ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt tttacaagtc
    23101 atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag ctttggcaat
    23161 atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg gtacctgtta
    23221 tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc agtaaacctc
    23281 gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct tttgacaggg
    23341 acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc aaatatcagt
    23401 tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt tctggtagct
    23461 atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg gaatacaaca
    23521 gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt gattcgcgaa
    23581 aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat ggaaaatcag
    23641 tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt atcggtccaa
    23701 atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca aaagatacag
    23761 gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa ttagccaaaa
    23821 aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg aaagaattag
    23881 tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac gaggaaatcg
    23941 ttcaggaatc actggaacac cttgggttag aagaaatagc ggatcaatcg attgacactc
    24001 tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa gacacggatt
    24061 atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt caaatcatgc
    24121 agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt cttcatgata
    24181 tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga cagttattta
    24241 cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta tacgaaatgg
    24301 acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa aactaacatt
    24361 aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc atttggttta
    24421 gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag cagcacacaa
    24481 actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt gccaaataat
    24541 ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc tcttggtgtt
    24601 ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc atcctataaa
    24661 aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa tcagcttcag
    24721 ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct aagtcaaatt
    24781 gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt ccagcaaaat
    24841 gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca attagaggaa
    24901 ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa aaaagcacta
    24961 gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag attcggtttc
    25021 atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc cactcacggt
    25081 caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt tgtagtagac
    25141 agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa tgaactggta
    25201 gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga tgtctggtat
    25261 ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa tcaagcattt
    25321 aaatagcata aataacagag gattaaactc tcatactatg taacaataat gtttcttaca
    25381 ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg taaaatcgta
    25441 ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac gtgaattcat
    25501 tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt gtgatccatt
    25561 ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg aaacttagat
    25621 aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg atgttccatc
    25681 tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat tttctgtcca
    25741 gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac gatgttccat
    25801 ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta ttttctgtcc
    25861 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa caatgttcaa
    25921 tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt taggcatgtg
    25981 tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg gcgggaagct
    26041 tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt ttatactcgc
    26101 ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa atatccaatg
    26161 ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa ccctcgatat
    26221 tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg attcctccaa
    26281 agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc cgtgaacaaa
    26341 aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta ttttttgtta
    26401 tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt tttccgttca
    26461 agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa tcataataaa
    26521 cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt agttgcatct
    26581 gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag aagtgacaaa
    26641 agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt tattagatat
    26701 cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg atacggcatt
    26761 tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt ctgtagtggc
    26821 tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca tggatgatcc
    26881 atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac caagcggctt
    26941 gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg gaaaattggc
    27001 gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc tgatgcagct
    27061 ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag atacggctaa
    27121 taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat tatctacgac
    27181 atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga tggaccattt
    27241 tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga ccgttctttt
    27301 agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg aggcaatcgt
    27361 acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa cagatctcga
    27421 ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa
    27481 acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc
    27541 tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat cattcggaga
    27601 attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc atcgtcgctt
    27661 tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt attattatga
    27721 atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct atgatcctat
    27781 gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc aaacacaaca
    27841 tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca gcattagtaa
    27901 tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag atccatttat
    27961 cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg atcggatgat
    28021 ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga taatcacaaa
    28081 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
    28141 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
    28201 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
    28261 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
    28321 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
    28381 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
    28441 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
    28501 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
    28561 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
    28621 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
    28681 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
    28741 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
    28801 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
    28861 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
    28921 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
    28981 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
    29041 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
    29101 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
    29161 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
    29221 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
    29281 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
    29341 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
    29401 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
    29461 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
    29521 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
    29581 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
    29641 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
    29701 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
    29761 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
    29821 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
    29881 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
    29941 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
    30001 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
    30061 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
    30121 gcaaagaagt cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga
    30181 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
    30241 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
    30301 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
    30361 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
    30421 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
    30481 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
    30541 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
    30601 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
    30661 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
    30721 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
    30781 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
    30841 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
    30901 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
    30961 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
    31021 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
    31081 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
    31141 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
    31201 tacagctcat cgtggaatca gaataaatat tcctgtagaa aaccaaagaa tcggaacctt
    31261 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
    31321 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
    31381 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
    31441 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
    31501 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
    31561 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
    31621 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
    31681 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
    31741 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
    31801 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
    31861 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
    31921 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
    31981 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
    32041 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
    32101 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
    32161 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
    32221 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
    32281 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
    32341 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
    32401 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
    32461 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
    32521 aacaaatagt aaatttttat tattgtagga tggttgggct ctttttataa caatataaaa
    32581 tataccattt tattaataaa aatgcatact agtaaatgat ataattctaa taacaggttt
    32641 gatcgcgaga aaggccaaat aaaacgctct ccaaaatgtt aaaaaaaaga caggacgatg
    32701 tatattatac aaacaagaat cgctgacaac agtgactcgg atccaggaaa tcagttttat
    32761 ccccagctag ttggtgaatg catggaaagt aatatacgta gaaagagctg atgactaatg
    32821 aattatgagt tttttttaag caaagaagat cacagaagtt attcattact taaatattta
    32881 gaagcaagct caaatttatc agagtcaata tcgaatgttc aagaagagtt gtcgctatcg
    32941 acatttctct tgaaaaaaac gatcgataag ctgaaacatg atttacaaaa gttcgatcta
    33001 gagaaaaatt tgcgagtaac cgtcagtgaa ttggatatat gtctggaaat taatggaaaa
    33061 tgttctagca aagctctgtt atctcgttat ataacggatt ctttatctat gaaaatggta
    33121 ttggctttct ttcaggaaaa atatatctca gtagaaaatt ttgctaaaca gcatcacgtg
    33181 agttattctg tggcttataa agtattacaa agactaaaaa gaaatctaaa aaaatatcaa
    33241 attttttttg aaaaga
//
LOCUS       DADGHT010000024        32119 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.024, whole genome shotgun sequence.
ACCESSION   DADGHT010000024 DADGHT010000000
VERSION     DADGHT010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.024"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            10..441
                     /gene="mraZ"
                     /locus_tag="JX887_000969"
     CDS             10..441
                     /gene="mraZ"
                     /locus_tag="JX887_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAX1256977.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            462..1421
                     /gene="rsmH"
                     /locus_tag="JX887_000970"
     CDS             462..1421
                     /gene="rsmH"
                     /locus_tag="JX887_000970"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAX1256978.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            1426..1827
                     /gene="ftsL"
                     /locus_tag="JX887_000971"
     CDS             1426..1827
                     /gene="ftsL"
                     /locus_tag="JX887_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAX1256979.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            1828..4020
                     /locus_tag="JX887_000972"
     CDS             1828..4020
                     /locus_tag="JX887_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAX1256980.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            4046..5008
                     /locus_tag="JX887_000973"
     CDS             4046..5008
                     /locus_tag="JX887_000973"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAX1256981.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            5022..6383
                     /locus_tag="JX887_000974"
     CDS             5022..6383
                     /locus_tag="JX887_000974"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAX1256982.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            6409..7497
                     /gene="murG"
                     /locus_tag="JX887_000975"
     CDS             6409..7497
                     /gene="murG"
                     /locus_tag="JX887_000975"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAX1256983.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            7512..8732
                     /locus_tag="JX887_000976"
     CDS             7512..8732
                     /locus_tag="JX887_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAX1256984.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            8888..10213
                     /gene="ftsA"
                     /locus_tag="JX887_000977"
     CDS             8888..10213
                     /gene="ftsA"
                     /locus_tag="JX887_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAX1256985.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            10236..11477
                     /gene="ftsZ"
                     /locus_tag="JX887_000978"
     CDS             10236..11477
                     /gene="ftsZ"
                     /locus_tag="JX887_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAX1256986.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            11494..12171
                     /locus_tag="JX887_000979"
     CDS             11494..12171
                     /locus_tag="JX887_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAX1256987.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            12185..12784
                     /locus_tag="JX887_000980"
     CDS             12185..12784
                     /locus_tag="JX887_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAX1256988.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            12799..13086
                     /locus_tag="JX887_000981"
     CDS             12799..13086
                     /locus_tag="JX887_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAX1256989.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            13135..13917
                     /locus_tag="JX887_000982"
     CDS             13135..13917
                     /locus_tag="JX887_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAX1256990.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            13938..14645
                     /locus_tag="JX887_000983"
     CDS             13938..14645
                     /locus_tag="JX887_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAX1256991.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            14907..17705
                     /gene="ileS"
                     /locus_tag="JX887_000984"
     CDS             14907..17705
                     /gene="ileS"
                     /locus_tag="JX887_000984"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAX1256992.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(17754..19280)
                     /locus_tag="JX887_000985"
     CDS             complement(17754..19280)
                     /locus_tag="JX887_000985"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAX1256993.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(19295..19942)
                     /locus_tag="JX887_000986"
     CDS             complement(19295..19942)
                     /locus_tag="JX887_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAX1256994.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(20126..20455)
                     /locus_tag="JX887_000987"
     CDS             complement(20126..20455)
                     /locus_tag="JX887_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAX1256995.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            20632..21360
                     /gene="sfsA"
                     /locus_tag="JX887_000988"
     CDS             20632..21360
                     /gene="sfsA"
                     /locus_tag="JX887_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAX1256996.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            21376..22389
                     /locus_tag="JX887_000989"
     CDS             21376..22389
                     /locus_tag="JX887_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1256997.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            22389..23666
                     /locus_tag="JX887_000990"
     CDS             22389..23666
                     /locus_tag="JX887_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAX1256998.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            23729..26431
                     /locus_tag="JX887_000991"
     CDS             23729..26431
                     /locus_tag="JX887_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1256999.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            26583..26900
                     /locus_tag="JX887_000992"
     CDS             26583..26900
                     /locus_tag="JX887_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1257000.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            26930..27250
                     /locus_tag="JX887_000993"
     CDS             26930..27250
                     /locus_tag="JX887_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAX1257001.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            27358..28818
                     /locus_tag="JX887_000994"
     CDS             27358..28818
                     /locus_tag="JX887_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1257002.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            28886..29107
                     /locus_tag="JX887_000995"
     CDS             28886..29107
                     /locus_tag="JX887_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257003.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            29138..29320
                     /locus_tag="JX887_000996"
     CDS             29138..29320
                     /locus_tag="JX887_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAX1257004.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            29320..29733
                     /locus_tag="JX887_000997"
     CDS             29320..29733
                     /locus_tag="JX887_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAX1257005.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            29856..31037
                     /locus_tag="JX887_000998"
     CDS             29856..31037
                     /locus_tag="JX887_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1257006.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            31426..31499
                     /locus_tag="JX887_000999"
     tRNA            31426..31499
                     /locus_tag="JX887_000999"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31460..31462,aa:Arg,seq:cct)
     gene            complement(31568..31843)
                     /locus_tag="JX887_001000"
     CDS             complement(31568..31843)
                     /locus_tag="JX887_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAX1257007.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
BASE COUNT        10784 a         5518 c         6825 g         8992 t
ORIGIN      
        1 gggctttcaa tgttgatggg tgaattccaa cataatattg atgcaaaagg acgtttaatc
       61 gtgccctcaa aacttcgtga agaacttggc gaaaagtttg ttctgacacg cggattggat
      121 ggctgtcttt tcggctatcc gatgagcgaa tgggaaaatc tggaagctaa actgaacgaa
      181 atgccgttgg ctaaaaaaga cgcacgtact tttgtgcgat tcttctattc ggctgccact
      241 gaatgcgaac ttgataaaca aggacgaatc aatataccca gcacgttaag aaattatgca
      301 gctttgacaa aaggttgcgt agtcatcggt gtatctaacc gaattgaaat ttgggatgag
      361 acacgatggc aagatttttc tgcagcagca gaagagaact ttgacgaaat tgctgaaagt
      421 atgattgatt tcggactata agaataggaa gaggctgact aatgactgaa acatttcaac
      481 actatacagt catgttgaaa gaaacggtag atggattgaa catcaaaccg gatggcgttt
      541 atgtagactg tacactcggc ggtgccggac atagtgaata tttattaagc caactaagtt
      601 ctaaagggca tctgtatgcg tttgaccaag atcaaaaagc aatcgatcac gccaagctgc
      661 gtttagcttc ttatgtcgaa caaggtatgg tcacatttat caaagcgaac ttcagagaat
      721 tagaagaacg cttgagtgag catgtagata aggtagacgg cattttgtat gatctagggg
      781 tttcctctcc tcagctagat gaagcagaac gtggatttag ttatcatcaa gatgcaccgt
      841 tggatatgcg catggatcag tcagctcctt tatccgctta tcacgtaatt aatgaatatt
      901 cctaccatga attagtaaag attttcttcc gctatggcga ggagaaattt tccaaacaaa
      961 ttgctcgtga aatcgaacga gtacgaaaaa caaaaccaat ccaaacaact ggtgagcttg
     1021 tcgaaatcat taaacaagtc atcccagctc ccgcaagaag aaaaggcggg catcctgcaa
     1081 aaagaatttt tcaagctgtg cggattgcag taaatgacga actcggtgcc gaagaggcct
     1141 ctttagaaca ggcaatccgg ttattgaaag tcaatggaag aatcagcgta atcacattcc
     1201 attcattgga agacagaatt gtcaaaagta tgtttaaaga atatagtacg gtacaagatc
     1261 taccaccggg acttcctgtc atacctgacg aattccaacc agaactgaaa gtcattactc
     1321 gtaaaccaat ccttccttca gaggaagagc taacagaaaa caatcgatca cgcagtgcaa
     1381 agttacgtat tgcagaaaaa ataagaatga aagaggagta gaatgatggc agaattaaag
     1441 aaaatgcaag attacgaata tgatttacct gaattggtgg atcagccgga acaacaaatg
     1501 cctgattctt cttcgaatca agaaatcatt cttccacaat caccggcaaa acgattaaag
     1561 cagatttctg ctttggaaaa aattgctgtg gcaagcgtgg cgattgctat tgttgcttta
     1621 tgtgttttaa cagttatgct gcgcacaaat atcagcggag ctgaaaaaga aatcacgtca
     1681 atacaaacag aaatcaatga taaaaagcaa gaaaaaacga gtttagaaca agaaaaaaac
     1741 gaactttctc gtactgaacg gattaaacaa atcgcagaag aaaaaggatt gtctattaat
     1801 gacgacaatt taaggaaagt gaagtaaatg agtcttaaaa ataaaattcg gcggtttatg
     1861 gaaaagaaaa atctaaatcc gatgaacaat cgcaaaaaag taggtatcat tttatttgct
     1921 acgagtattg gattgttctt tttatttgcc gtccgtttct cgtatatcgt tattggaggt
     1981 catgttgctg gtacctcatt agctgaaaaa acaaaacagt tgtaccaagg aagtgaagta
     2041 gtaaaagcaa aaagaggaac gatttatgat cgtaacggtg tggcgctcgc agaagatgcc
     2101 tcctcttatt caattaaagc gatactctca aaaacatata cctctgggga taaaaaactg
     2161 tatgttgaag aaaagaattt tgataaaata gcagaaatcc tgcataagaa tctttctata
     2221 gacaaaaaag atgcactgaa tattttagag gacggcgcaa aaaaagagct gtatcaagtt
     2281 gaatttggta gctatgggaa aaatatctcc caagaaacca agcaaaacat cgaagcggac
     2341 atgaaaaaag aaggtgtcgc tggtctttat tttgtcgacc atcaggctcg gatgtatcca
     2401 aatggcgtct tttcttctca ttttattgga tacgcagttc cagacaaaga tgagaatggc
     2461 ttagttggta aactaggttt ggagtctgct tacaatgata tcttgagcgg taaagatggt
     2521 aagattattt atcaaaaaga taattttcaa aatcctctgc caggtacagt ggcagaagaa
     2581 gaaaaagctg tcgacggaca agatatctac acgactttag acagcagact acaaagttat
     2641 ttagaaacac tgatggatca agtaaatgaa gaatatcagc cagaagaatt gacagcagtc
     2701 ctgatgaaag caaaaaccgg agaaatcttg gcaatgggac aacgacctac tttcaatcct
     2761 gaaacaatgg aaggattgac tggaaaagat gctatctggc gtaatttctt ggtacaagat
     2821 agttatgaac caggatcaac catgaaagtt ttcactactg cagctgctat cgaagaagga
     2881 gaattcaacg agaatgaaac cttccaatct ggaaaaatcc aagtagaaga tgctacgatc
     2941 aatgaccatg actttggtga aaaaggtgtg ctgaccatgc gtcaagctct ttcatggtca
     3001 agtaacgtcg ggatggtcat actggaacag cgattaggcg gacgatggta taactattta
     3061 caaaaactgg gatttggaca aagtactcat tctggattag atgatgaagt aaacggtgct
     3121 ttacctacat taaatattgt cgaccgagca atgagtgctt atggacaagc ggtaggtgtg
     3181 acgaatttcc aaatgatgaa agctttcact tctattgcga ataacggtac aatgattcaa
     3241 cctcgatata tcagcaaagt ggtggatccc caaactggag aagagcgaac aactcaaaca
     3301 gaagttctag ggcaaccttt ttcaaaagaa acaacagaaa aagtccgtga atatatgaga
     3361 gatgttgtcg aaagcgaaaa ctacggtagt gcttatggtg tatatagtgt acctggatac
     3421 aatgtatcgg caaaaaacgg aacagcccaa atcgcttctg atacaggggg atatcaaaca
     3481 ggagatacag cctacctgta ttcgattgtg gagatggttc cttctgaaga tccagactat
     3541 gtcttgtatc taacaatgaa acaccctaag acatatgatc gaatggcatt ggctaaaatc
     3601 gcaaatccat tgatgaaacg ggcaatggat tttaaagaaa ctgaagaaga ttcagataca
     3661 gaaacaaaaa cagaaaaagt atccgtagcc gattatcgta atcttgaagc ggacgttgca
     3721 gcagctgatg ctcaaaaaag tggactgcaa cctgtagtga tcggtaatgg taaaaaagta
     3781 caaaaacaat ctactgccaa cggtgatcag ttgatctctg gagaaaaact gatcctatat
     3841 actggtggtg ataagctgat gcctgacgta acaggatggt caaaagcaga tatcatgaag
     3901 ctggggaaaa tcctcggtat tgaagttagt tttgatggag atggttattg tgtcaaacaa
     3961 gaacttgctc catatgaaaa aatcactgaa gacaaactta gttttacttt agaagaataa
     4021 gaagagaaat aggagagaaa agagcatgga atggacacaa gcattgattc ccattgtcag
     4081 cagttgtgca atgacaattg ccgcaatgcc gctatttatt ggttattttc aaatgaaaaa
     4141 gcaaggtcag gcgattcgtg aggagggacc aaagtggcac aatagcaaag ccggaactcc
     4201 tacaatgggc ggcttagtgt ttctgatcgg ctctattttg acaggaattt gggttggagc
     4261 ttggcaaaaa cagctaactc ctactctttt catcttgctt tttgtattag cgttatacgg
     4321 agtaatcggc tttcttgatg attttataaa aatattcaag aaaagaaaca tgggactgaa
     4381 ctcgaagcag aaattgattg gacagattct agggggaatc atcttttatc ttgtttaccg
     4441 ttctgaaggt tatccaggtg tattgaattt cttcggacta gatctacctt taggaatcat
     4501 ttatggtatt ttcgctctct tctggcttgt tggattttca aatgcagtaa atctgacaga
     4561 tggcatcgat ggattagttg ctggcttagg aagtatctct tttgcagctt acggtctaat
     4621 tgcttggcat cagcatcagt atgatgtatt aatcatttgc ttaagtgttt taggaggttt
     4681 actgggtttc ttcgtctaca acagaaaacc tgccaagatt tttatgggag atgtcggttc
     4741 attagcgttg ggcggacttt tagcggcaat ttctataatg ctaaaccaag aatggacatt
     4801 gcttttgatt ggtttgatct atgttatgga aacagcaagt gtgatgcttc aagttacttc
     4861 ctttaagctt acaggaaaac gaatttttaa aatgtctcca attcatcatc actttgaaat
     4921 gtgcggatgg tcggagtgga agattgatac agttttttgg ttgatcagca ttgtgacttc
     4981 gttgatcaca ttatggatcg tttggtagga gatgacggga aatgaaaaaa atatcaacat
     5041 atgaaaataa gaaagtgctt gtcttaggac tcgcaaaaag cggagtaagt gcggccaaat
     5101 tattacatga attgggcgca cttgtcaccg ttaatgatgg aaaacctttt gacgaaaatc
     5161 cggaagcaca agagctgctt tctttaggga taaaagtaat aacaggtagt catccaatcg
     5221 aattgttgga tgaagaattt tcattgatgg tcaaaaatcc agggattccc tacagtcatc
     5281 ctttagtagc aaaagcccaa gaaatgggta ttccggtaat tacggaagtt gagctagctt
     5341 acgaagtagc ggaatgccca attattggga ttacaggaac gaacggaaaa acaacgacaa
     5401 caacgatgac aggactacta ctgaatgcag gagcagatca aggaattgca cgtttagcgg
     5461 gtaatattgg gtatccagca agtggtgtag cgcaagaagc aaaatcagaa gataaaattg
     5521 tgatggaatt gtctagcttc caactcatgg gaatcacaga tttccgccct catatagcgg
     5581 tgattaccaa tatctatgaa gcacatattg attatcatgg tacaagaaaa gaatatgtca
     5641 aagctaaatg gaaccttcaa aaaaacatga cagaaaaaga ttatctgatc cttaactgga
     5701 atcagtcaga actacaagaa ttagcgcaaa gaacaaaagc acgcgtactg cctttctcga
     5761 caaaagaagt gttggaagac ggtgtgtatg ctgacgatta ctcaatatac tataaaaaag
     5821 aaaaaataat ggaaatatct gaacttggcg taccaggtaa gcataatgta gaaaatgcac
     5881 tagctgctat ttctgtagca aaattgtatg gtatatcaaa tgaagctata cgagaaacgt
     5941 tgcatttttt ccatggcgta ccacatcgta cgcaatatgt aggagaaatc caaggcagaa
     6001 aattttataa tgattcaaaa gcaaccaata ttttagcgac taaaatggct ctaagtggat
     6061 ttgaaacgtc taaggtcgtg ttattggctg gcggattaga cagaggaaat acatttgatg
     6121 aattaattcc ttcattaaaa ggaatcaaag caatggtcgt atttggccaa acaaaagaaa
     6181 agttgatgga tgctggaaaa aaagcaggca tcgagacaat agtaacagcc gattctgtag
     6241 aacaagcagt tcctttagca ttagaaaaca gtacagatgg tgatgtagtt ttattatcac
     6301 cagcgaatgc cagctgggat caatacccaa attttgaaac tagaggaaac agattcatgg
     6361 aagctgtgaa ccgattaaaa tagaaaaagt agaagcgagc gataaaaaat gaaaattttg
     6421 gttacaggcg gaggaacagg gggacatatt tatccagctc ttgcctttgt caattatgta
     6481 aagactcaag aaccgaatgc tgaattcatg tatgtgggag caaaacgagg tctagaaaac
     6541 aaaatcgtcc ctgatacagg aatgcctttc cataccttgg agattcaagg atttaaacga
     6601 aaaatttcca tgcataacat caagacggtc cgattgtttc ttaagagtat ccgtcaagca
     6661 aaaaaaatcc tcagtgattt tcaaccagat atcgttatcg gtactggagg atatgtttcc
     6721 ggagcggtag tgtacgctgc agccaaaatg ggtattccaa cagttatcca tgaacaaaac
     6781 agtgtaccag gtgttaccaa taaattttta agccgatatg tggatcggat cgctctttca
     6841 tttaaagatg cggcttcctt ttttcctgaa aacaaagcag ttcttgtagg taatcctcga
     6901 gcacaagaag tagcagatac taaaaaatca gatattttga aaacatttga tttggatcca
     6961 gaaaagaaaa cagtcttgat ttttggcggt agtcaaggag cacttaaaat caatcaagca
     7021 gtatcagttt ttttaagtga atatattcct tcttcttacc aagttttgta tgcttcagga
     7081 gatagatatt atgaagagat cctaaataaa ataaatcctg aaatacaaaa tattagtgtc
     7141 cagccttata tcaaaaatat ggcagaggtc atggcttcca gtgatctgct ggtggggcgt
     7201 gctggtgcaa cttcgatcgc agaattcaca gctctggggt taccggcagt gttggttccc
     7261 agcccatatg ttacgaatga tcatcagact aaaaatgcaa tgagtcttgt tcacgcagga
     7321 gcagcaaaaa tgattgcaga taatgaacta acaggtgaat cactaagtca gacagtcaac
     7381 gaaatcatgg gtgatgaaga attgcaaaag caaatgtgcc gagcttctaa agaacaagga
     7441 atccctgatg cttcaaaacg tctttatgac ttagtaaaac aaataatcaa aaaataaagg
     7501 cggtggtctt agtgagtaag aaaaaagaac caaaaaaatt gtctcatccg tcttctgatg
     7561 aaaacaattt gactccttgg caaaaggcta accgaaaata tctggcagaa caagagatga
     7621 aaaaccaaga gccaaaaaaa gaagacataa cattagatac acccctttca gattctgaag
     7681 aagaaaaaac ggttcaagag gaacagcaag aagaaagcca gtccgagaaa aaaatcgaat
     7741 tttttgaaga gatcaagcaa aagaaaaacg gtggaccata taacggttct tttttgaacc
     7801 ggctgcccaa tttaaaaagt caacggcaca aagtactatt tcgtcggtta gctttgatca
     7861 tcactgtatt gggtataccg ctgatttttt tgatctatta tgtttctcct tatagcaaat
     7921 tacaagcagt tgcagtatca ggcaataaga cagtcaacag ccaagaaatc atctctgata
     7981 caaaattgtc attaggagaa aatgtttggg gacagtattt tcatcgatct acttatatcg
     8041 atcgccttaa aaaagcacag ccaagaatcg aaacagcaaa tatacatttc aaagggatga
     8101 atgaattcga tttggatgta acagaatata aagagattgc tttgatcgca aaaaacaatc
     8161 aatactaccc agtgattgaa aatggaacag tattagatga aaaagtagca aatcctacaa
     8221 aaaatctccc tatcttggaa gagttcaaag actctgcaaa aatcaaagaa ttaacaaagc
     8281 aatacaatca gttatcatca gaattacaaa aagcaatttc tgaaatcaag tacacgccaa
     8341 gagcaagcaa taaaaatctg atccaattga atatgaatga cggcaatcaa gttattgtaa
     8401 atatcaataa tcttgcgaac caaatgaaat attattcgca agtagccaaa gatatggatg
     8461 aaaaaggtgt gatcgacatg gaagttggta tcttctcgca tccttacggt agcactcaag
     8521 aaacggaaga atcgggccaa tcggaagaaa caactgaaag tgaagaaaat gcggatcaaa
     8581 caaacgaatc aagtgaagag gcagaaacgc aaaaagcaca aacacctgga tcgtctagca
     8641 caaacggatc atctgattca aatgattcaa gtgaaacaag tcaaatagaa gataatccaa
     8701 gtacaactcc gtcaagttta aatgaaaatt gataaaacaa ctttaaaaag taagaatgta
     8761 ctttctaaaa accagtaatt tatggtagaa ttggaagcag tgaatatatc tattaataag
     8821 tatattttaa aacggacgct agttgttcgc ttgtatatgg aatagtaagt aggagggaat
     8881 cccattcatg gcaaaaacag gaatgtatgt aggccttgat attggaacga catctgttaa
     8941 agttgtcgtg gctgaatata tcgacagcca aatgaatatt attggagtag gaaacgcaaa
     9001 atcagaaggg attaaccgag gcattatcgt tgatatcgat aaaacggtcc aagcgataca
     9061 acgagcagta cgacaagcag aagaaaaagc aggtatccag atcaaaggcg taagtgtcgg
     9121 tttgccagca aacatgcttg aagtagaaaa ttgccaggga atgattgcag ttaacggaga
     9181 ttcaaaggaa atcaccgatg aagatgtcag aaatgtggct tcagctgccc ttgttcgttc
     9241 aatacctcct gaacgtcaaa tcgtgtcaat attgccacaa gattttactg tcgatgggtt
     9301 cgagggaatc aaagatcctc gtggaatgat cggcgtaaga ttagaaatgt acggtctgtt
     9361 gtttacagga cctaaaacga tcatccataa catacgtaaa tgcgtggaaa atgccggatt
     9421 aatcgtcaac gaaatggtga ttactccttt agcgctgact gaatcaattc tttctgacgg
     9481 agaaaaagat tttggtacga tcgtcattga tatgggtggc ggccaaacaa caacggctgt
     9541 tatgcatgat aagcaattga agtttaccaa tcttgaccaa gaaggtggcg aatttgtcac
     9601 taaagatatc tctattgtat taaatacgtc atttaacaat gcagaagcgt tgaaaataaa
     9661 ctacggggat gcatacccag aacggacatc accagatgaa gaatttccag tagatgtgat
     9721 tggtcagtca gaaccagtga aagtcgatga acgctacttg tcagaaatta tttcagctcg
     9781 aatggaacag attttcaaca aagcaaaaga tgcattggac caaatcgaag cattagagtt
     9841 gccaggtggc gtcgtattga caggcggagc tgctagtctt cctggtgttg tggacttggc
     9901 acaagaaatc ttcggcgtaa atgtaaaatt gtatgttcca aatcacatgg ggctgagaaa
     9961 cccggtattt acaaatgtaa taagtatcgt ggattattca gcaaacttga gtgaagtgta
    10021 tcaattggca aaaattgctg ttacgggtga aacctcagca gctcgtcaaa tggtagttga
    10081 acaagaaaca acaaacacat atgagagcta tgaagcacct gaagaaacaa tctacgatga
    10141 gccggaacca aaagagtccg gagaaaatgt aaaaaataaa atcaagggtt tctttacaaa
    10201 tatttttgat taattcatcc tgggaggaat aagatatgga attctcaatt gataataata
    10261 tcaatgacgg cgcagtaatc aaagtcatcg gagtcggtgg tggcggtgga aatgctgtaa
    10321 accgaatgat tgaagaaaac gttaaaggtg ttgaattcat tacagccaac acagacgtgc
    10381 aagcattaaa aaattcaaaa gctgaaacag ttatccaatt aggccccaaa tatactcgtg
    10441 gtttaggtgc tggttctcag ccagaagttg gacaaaaagc ggcagaagaa agtgaacaat
    10501 ccttacgcga agctttagac ggtgcagata tgattttcat cactgcagga atgggtggag
    10561 gaaccggtac aggtgctgca ccaatcgttg caggtatcgc gaaagaattg ggcgcattga
    10621 ctgttggtgt cgtgacacgt ccattcactt ttgaaggacc gaaacgtggc cgttttgctg
    10681 cagaaggtat cgctcgtttg aaagaaaatg tggatacatt attaattatc tcaaataacc
    10741 gtttattaga agttgtagat aaaaagacac cgatgcttga agctttccgt gaagcagata
    10801 atgttttacg acaaggtgta caaggtatct ctgatttgat cacagcgcca ggttacgtta
    10861 accttgactt tgctgacgtg aaaacagtga tggaaaacca aggtacagca ttgatgggga
    10921 tcggtgtggc tagtggagaa gatcgcgtag tagaagcaac gaaaaaagca atctcctctc
    10981 cattgcttga aacatctatt gatggagctg aacaagtact tcttaacatc acaggcggtt
    11041 tggatatgac attgttcgaa gcacaagatg cttcagatat cgtagcaaat gcagcaactg
    11101 gcgatgtaaa tatcattcta ggtacatcta tcaatgaaga aatgggcgat gaaatccgtg
    11161 tgacggtcat cgcaacaggt atcgatgaat caaaaaagga acgcaagtct agccgaccag
    11221 ctagacaagc acaaatgcaa tcacctgctc aaaagactgt attagatatg gatcaagcta
    11281 aaccaacttc ttcagaagaa gaaaacagtt ttggcgattg ggatatcaga cgtgaacaaa
    11341 atgttcgtcc tagagttgat gattccaatt ttgacaatat cgaaaaaaaa gaatttgata
    11401 cattcaaccg cgaagaaaca aaatctcatg gcgatgatga attaaatacg ccaccgtttt
    11461 tccgtcgtaa aaaataaagg agaggaagag cacatgattg ctgacaactt gcagaaaatc
    11521 aagcaagaaa ttcaggattc gtgtgctctt gttcatcgtg atccgaaaga agttacatta
    11581 gtagctgtaa caaaatctgt tgaatccgct caagctgaag aattggttag agctggcgtt
    11641 atgaattgtg cagaaaaccg agtagataaa ttattagaaa agaaacaaga tttatttgat
    11701 tttcctgaaa taaagtggca tttaattggt aatttacagc gcagaaaggt aaaattgatt
    11761 gtaaatgaaa ttgattactt tcatgcgttg gacagtttaa gattagcaga agaaatccag
    11821 aagcggttag agaaagaatt atcctgtttt attgaagtaa atgtttctgg tgaggaatca
    11881 aaacatggaa tttcaccaga tgagctttta ccgtttgtgg aatctttagc tgcctgcaca
    11941 aaaatcaagg ttgttgggtt gatgactatg gcgcctaaag aagcttctga tgagcaaatc
    12001 cataaagtgt ttggtacgct gaaagaattg cgtgatcttg ttcaagcaaa aggttatgcc
    12061 catgcaccat gtagtgaatt aagtatgggg atgagtcaag actttcaaat tgcgattgaa
    12121 gaaggtgcaa catttatccg tgtaggaaca gcgctattca aagacgaata aaggaggaac
    12181 aaaaatgccg cttttaaaca gaggagcaat tgctaatttt ttcggattag ctgatgagga
    12241 agagtacgaa taccaagatt atcctgaaac aacaaaaaag gctgtacagc caactaaaaa
    12301 aaatacaaca cagaatcaat caactcattc tgtatctgct gcgaatactc atgaaaaaca
    12361 aaaaacggcg acttcacgtc ctgtaacgca tgaaagtatt cagccggctg aaaagaaaaa
    12421 agtaattgaa ctacatcaat cacctacaaa aactgtagcg aaagaaagaa cagcttcaag
    12481 aacctctaca caacctaaag caaatcttgc tggaaaaatc actgtaatgg aaccaagagc
    12541 ttattctgaa gctatggcga ttgctaaacg aatcattgct ggagaagcaa ccttagtgaa
    12601 ttttcattta gtagaagaaa aacaagcgag aagaatcgtt gattttctaa caggaacagt
    12661 ttatgcacta gatggagata tcaaacgtgt tggagatgag atttttcttt gtacaccgac
    12721 tgggatggag attgacagtt caaccgctca atcttttgca gatgcgaatt tgtttgatct
    12781 gtaagaggag gaactacgat ttatactatt gcactattac ttcatttact tcaacgggca
    12841 gcctatttct atagcattat cttgatggta tatgcattgc tctcttggtt tccaggcggg
    12901 tatcaatcag ggctaggacg attattagct aagatctgcg aaccgtatat cagtttgttc
    12961 gatcgtctgc ctttgaggat tggacccttg gatttcacaa ttttaggggc aatcctgatc
    13021 ttgaacttag ccgtacaagg tttagcacag atcgttatat ggataactgt ccatttagtt
    13081 tattgattga agcaacaaaa tctttattct cagaatagat aggaggggaa aattttggat
    13141 gcaaatgtat accagcactt tcgggcagat gaacgtacat ttatcgattc ggtaggcgat
    13201 tggattgaac aggttcaagg acaatatgca ccctatctga ccgaatttct tgacccaaga
    13261 caatcctata ttttagaaac actgattcga caaagcagtg atttgcgttt catgttttat
    13321 ggcggatatg aacaggcaga aagaaaaaga tgtttgattt tccccgatta ttacgaacct
    13381 gtagaggaag attttgaaac agcattgtat gaaatccatt atcctagcaa atttgccagc
    13441 ctaagtcatg ggaaaatcct tggaacttta gtgggaacgg ggatcaaacg ctcttacttt
    13501 ggcgatatca tctcggacgg tgatcgctgg caagtattta ttgcaaatga ggtggatcat
    13561 tttgttgctg cacaagtaac aaagattgga aaggttgctg tacgcttgga accaatcaaa
    13621 tacacagaaa tgattatgcc gaaagatagc tggacacaag aaagaggaac agttagttcc
    13681 atgcgactag acagtgtgat ctctgagatt tataatattt ccagacagcg gtccaagcag
    13741 ctgatcgaag ctggtaaagt aaaagtgaac tggacagaaa atacaagacc tgattttgta
    13801 cttgaactat tagatattat ttcagtcaga ggttatggca gagtccagat ccaagaactt
    13861 gaggggaaga cgaaaaaaga aaagtacagg gtactgttcg gtgtattacg taaataaaat
    13921 aaaaaggtgg tttactcatg gctttaactc cattagatat ccaaaataag acattcccga
    13981 caaaaatgcg gggatataat caagacgaag tagatgattt cttagattta gttgttcgtg
    14041 actatgagga attgactcaa agaaatcgag aattagaaaa agcagtcaaa cattctgaag
    14101 aaaaacttga gtacttcaat gaattaaaag atgctttgaa ccaatcaatc atcgtagctc
    14161 aagatacggc tgataaagta aaaacaagtg caagcaagga atccgaagtg atcgttactt
    14221 ctgcacaaaa caaagcagat gagttagttg cgaacgctga aaaacgtgca catcaattaa
    14281 caactgatgc agaagaaaaa gcaagaaaaa tcttgacaga tgcaacagaa aaagcaagac
    14341 agcttgcgac agaaactgaa gatcttaaga aaaaaacacg agtattccat caacgtatca
    14401 gcttgatgct tgagtctcaa ttagaacaag tgaaaagtcc ggaatgggat gaaattttac
    14461 aaccattctc cagctacgtg actgacagcc atgaagtgat caaagaagtt ttagcaaaac
    14521 agcttgacaa tgaaaatgat actgatgtaa actcagacac aggagtcata gaagcaccta
    14581 tgacggcatt tgatacacag gctattgata tctcgatcgt gcctggtgaa aatgaaaacg
    14641 agtagaacag aaaagcactt tgttattctt aaagcgagcc gatgagagtg gaagttcggt
    14701 aagacactgc atggtgaaag atcctctact tgagacctgc ttttccgaaa ttagagtaag
    14761 aagcagcggc tgacctcgtt attggtcaca gagagtttgc actagataga tgcaactaaa
    14821 tttgggtggt accacggcat gttcgtccct tgcggctgaa catgcttttt tgtgtccgga
    14881 aaacaaataa aggagtgtat ggttgaatga aaatgaaaga aaccttgcaa ttaggaaaaa
    14941 caaaattccc tatgcgtggt aatttgccaa accgagaagg cgagtggcaa aaagaatggg
    15001 aagaaaatcg aatctaccaa aaaagacaag agttgaacga aggaaaacct agctttgttc
    15061 ttcatgatgg acctccatat gccaatggta atatccattt aggacattca ttgaataaaa
    15121 tcagtaaaga cattatcatt cgttcaaaat caatgtctgg ctatcgtgca ccatatgttc
    15181 caggatggga tacacatgga ttgccgattg aacaagtatt ggctaataaa ggcgtgaaac
    15241 gtaaagaaat gtccatggca gaatacttgg aaaaatgtcg tgaatatgca ctttcccaag
    15301 tagataagca acgagcagat ttcaaacgcc taggagttgc aggagattgg gaacatcctt
    15361 atgttacatt agatccttct tatgaagctg cacaagtacg cgtatttggt aaaatggctg
    15421 aaaaaggcta tatttacaaa ggattgaaac caatttactg gtctccgtca agtgagtctt
    15481 ctttagcgga agctgaaatt gaatataaag atgtaaaatc tccatctatt tttgtagctt
    15541 tcaatgtcaa agacggcaaa gatattcttg atgaagatac agcttttgtc atttggacga
    15601 caacaccatg gacattgcca gcaaaccaag gtattgctgt aaatccaaaa tttacgtatg
    15661 tattggtgga agccgatggc cgtaagtttg tcgtagcgaa agatttgcta gaaacagtcc
    15721 aatcagaaat cggttgggaa aatgtaacag ttctaaaaga atttgctgga caagaaatgg
    15781 aatatatgac tgcaagtcat ccattctatg aacgtgaatc acttgtgatt ttaggcgatc
    15841 atgttacttt agacgctggt actggattag tccatactgc tccaggacat ggggaagatg
    15901 actatatcgc tggtagcaaa tataaactat ctgtagtgtc acctgtagac tcaaaaggat
    15961 tgtttacaga agaagcacct ggatttgaag gtatctttta tgacaaagca aatcctatga
    16021 tcactgatct attaaaagaa aaaggagctt tgctgaagct agatttcttt actcatagtt
    16081 atcctcacga ttggcggacg aaaaagcctg tgatctatcg ggcaactcca caatggtttg
    16141 catctatcga taaattccgt cagaatattt tggatgaagt agaaaaagta gagtgggtta
    16201 tcccatgggg taaaacacgt ttgtataata tgatccgtga ccgcggcgat tgggtaattt
    16261 cccgtcagcg tgcatgggga gtaccacttc cgattttcta tgctgaaaat ggagaagcaa
    16321 tcatcacacc agaaacaatc gaacatgtgg caaaattatt tgctgaacat ggatcaatta
    16381 tctggtttga aaaagaagcg aaagaacttc ttcctgaagg atttacccac ccaggttctc
    16441 ctaatggcga atttacaaaa gaaaaagata tcatggatgt ctggtttgat tctggttctt
    16501 ctcatgaagc tgttttacgt cagcgaccag aattatcatt cccagcagat atgtatttag
    16561 aaggatcaga ccaatatcgt ggctggttca actcaagtat cacgactagt gtggctatca
    16621 atggtgtagc accatacaaa tcagttattt ctcaaggatt tgctttagat ggtgaaggcc
    16681 gtaagatgag taaatcttta ggaaacatca ttgcaccaga aaaagtgatc aaacaatttg
    16741 gtgcagatat ccttcgctta tgggtatcta gtgtagatta tgaagcagat gttcgtgttt
    16801 ctatggatat cttaagtcaa gtggcagaag tatatcgtaa aatcagaaat acgatgcgtt
    16861 tcttattagc gaatacagaa gatttcgatc ctaaaaaaga tactgtttcg tacaatgatt
    16921 tacgttctgt agacaaatat atgaccgttc gattgaacca agtaatcaaa gaaatccgag
    16981 aagaagggta cgacaaatat aacttcatgc atatttaccg tacagttatg aacttcttga
    17041 cggttgatct atcgtcattc tacctggatt ttgctaaaga tgtagtttat attgaagcag
    17101 aagatgatta tcaacgtcgt tgcatgcaaa ctgttttcta tcaaacagct gtagctttga
    17161 caaaattatt gactcctatc attccgcata cagcagaaga aatctggtca ttcctgaaag
    17221 aagaagagga gtacgttcag ttaagcgagt ttcctggtta tgaagagttt gcaaaccaag
    17281 aagaattgat ggatacctgg actgctttca tggacttccg tgataatgtc ttaaaagcat
    17341 tggaagaagc aagaaacagc aaattgattg gtaaatcttt ggaagcaaaa ctaactgttt
    17401 atccaaaaca acaagttcgt gaaatgttaa aagctttgga tgcagatatt gcacaattat
    17461 tgatcgtttc accagactac tttgaagtta tggcagcaga tgaacaagtg ccagataacg
    17521 ctatggtatt tgatgatgtt gctattacag tggaaaaagc agacggggaa acttgcgatc
    17581 gctgtcgcca agttcgtaaa gatgtaggag tagatgaaaa acttcctcat ctatgcggtc
    17641 gttgtgcaaa aatcgttgaa gacttctatc ctgaagctgt agctgaagga ttcgaagaaa
    17701 agtaaaaggg aaaagggggt gtgacatgtt ctttgtcaca cccccttttg ttatcaatcg
    17761 tttaattttc cacgttcacg ataccagtta tctggttgcc agatccattc gaatccgtct
    17821 ttttcaagta gttcgaaagc tgctttaggt cccattgatc cagctttgta gttgggaaaa
    17881 tccggttgtg tttggtccca agcttttcga atgacatcca cgatatgcca agattgagcg
    17941 acttcttccc aatgagagaa gttcgttcca tcaccattca acgcatctaa tagtaatttt
    18001 tcgtaagctt ctgggctatt ttcaaccatt tctgcactat ttctaaattc caatttgatt
    18061 ggttccgttt caaatccttg ccctacttct ttcccattca aggataaaga aaatccttca
    18121 gttggctgaa tatagatcgt tagaacatta ggtggaagtg tcgtatcgtc acatggttca
    18181 tcgacagatg ttttgaatac attaacagga acttgtttga atacgatgtt gatccgagtc
    18241 cctttttcag tcaaacgttt gcctgtacgt acatagaaag gaacacctga ccaacggaag
    18301 ttatcgatag tgaatttgcc tgcgacgaat gtttcagtct ctgattgagc atccactttg
    18361 tcttcttcgc gatagccctt gaattgtaca ccatccaatt caccttgagc atattgcccg
    18421 cgaacgaagt tttctaacac ttcttcttcg ttataaatgc ggatagcttt caatgctttg
    18481 atcttttctg tacggatttc tttttcggaa aatgctactg gcggttccat tgcaagtaat
    18541 gctacaacct gtaaaatatg attttgcacc atgtctttaa gtgcgccact atgatcgtag
    18601 tagcccccgc gatcttctac accgaggttt tcgccaaaag taatttggat attgtcgata
    18661 tagcgattgt tccattgagc ctcaaaaata ttattggcaa aacggatagc tgagatgttt
    18721 tggatcattt cttttcctaa ataatgatca atcctgaaaa tatcttgttc tgggaatact
    18781 tctctgattt gctggttcaa ttcaaaagca gactggtaat cagaaccgaa cggtttttct
    18841 atgatcaaac gattgaagcc attttttgtc ataatatttt gtgatttcaa atgagaaacg
    18901 atcgttccaa aaaattgagg tgccatagcc aaataataga cacggttacc gtttaattga
    18961 tagtgtccat ctaatcggtc agacaattct tttaatgtct gataatgcgt tgaatcattt
    19021 acatcatggg attgatagta aaaatggctt gcaaaggtag ttgcttcttc atctgaagga
    19081 ttcaatgcac ggattgtttc tttgacaact tcacggtagt gctcatcgct ccagggacgg
    19141 cgagcggttc cgattacagc aaaatgctcg cctaaatttc cttttctgta aaggcggaac
    19201 aaagacgggt acaatttacg ctgggctagg tcacctgtac cgccgaatat cgtaaacaat
    19261 acattttttt cattagacat gtggatacac tcctttatat tttatcgaca aaaatcgtgc
    19321 tggccgcctt aaagctgacg gggattttct ttctatcatt ttggatagtg atcggtcctt
    19381 cataagctgc gatgtcaacg atctcatatt cttcgttgat attcaggtca atagtgacta
    19441 agtaatccaa caattctttt tcatcaagca ctcgtgcgat acgcactttt gtaccgacag
    19501 gataggactc caatgtttgt cggcgttctt catggacaac ttcctctttt ttaggaatcg
    19561 atcctccatg aggacaatgt tcaggatgat tcaaatagtt ttctaaatga tctgcaagat
    19621 gttccgaagt cacatgttcc aatacttcag catcatcatg gacttcattc cagctatagt
    19681 ctaaatgttc aactaaaaaa acttcccata agcgatgttt gcgaatcaga ctgctagctt
    19741 tttgcagtcc gcttgcagtc aattgtacac cttgataagg ggaatgttct acaagctctt
    19801 ctttcacaag tttagaaatc atttcactga cagatgcagc tgagacatct agactagata
    19861 cgatttgttt attgttgact ttcgttgtat ctccacctag ttctaaaatg attttcaaat
    19921 aatcttctcg atttggtgtc atattcgatc atcctttcat ggtaaaaaac catcattagt
    19981 aagtgtaaca aaaaaaacgt taattgacta tttttctaaa taaaaaacaa aggattttta
    20041 gacgttttta caacaaaaaa cgaaagatga tagagaagac tcattctttc gtttataaag
    20101 gatatatata tacattggga gggatctatt tttcagataa caacttatat gaagtgtctg
    20161 cagattcgtc ataaagagtt tgttcgggat aagaaaagat aagataaaaa ccatactgat
    20221 cacgtacgac taaacgatat tcatctattt ctaccacaga tgtgccaaga gactgaccgt
    20281 tgatcaaaaa cgtgtaatca gatgtaatct gtaattgttg tttttgctgg ctatcactaa
    20341 agaaccatgt accttgatac tttgagagtc cttctgactt ttccgcttgt tttttctttt
    20401 tcaagtaaat aaaacttgag agaacggtaa tgagtgaacc aagaaaatag atcatttttt
    20461 ttatcaccaa atcactcctt tatgagaaaa taatcgcata gacatattct ttcttcttta
    20521 tttcattgta ccgaataaaa gctaaaattt ctctaagact ttcgactggt ttttttactg
    20581 tttttctaca aattatgata ggatacatag taggaagaaa ggtgacataa tttgaagtat
    20641 cagcaagtgg aaatagcttt ttttattgac cgcccgaatc ggtttatagc acattgtatg
    20701 aaaaaagacg gagaaataat tattgcgcat gtcaaaaata caggtagagg aaaagaggtc
    20761 ctgataccag gcgctgaagt ggctattgta tttgctcctg gacctaaacg gaaaaccgcc
    20821 tatgatctga ttgctgtaaa aaagaagggt gactggttta atatcgatag tcaattgcct
    20881 aatcggctgg caattgatgg tattttagac ggcacgatcc ttttaccagg attaactggt
    20941 ccatttacgg tatacaagcg tgaagtaact tatcttcact ccaaatttga tatttattta
    21001 gagacggtgg tcggacaaaa agcatttgtt gaagtcaaag gtatgacact tgaaaataaa
    21061 gcgattggtg cttttcctga tgcgcccaca ctcagaggat tgaaacatat aggagaatta
    21121 acgtatgccg cacaagatgg ttatgccgct tatgtcttgt ttattgctca gttcgaacat
    21181 cttcatctgg caacgatcca tgaagaaatg caaccagcac tagctgatat ggttcgacat
    21241 gcgcagcaaa gcggagttca aatcctcgcc tataattgtc aagtatcggc agatgaggta
    21301 actgtcaagc aggccattcc atttgatgta gatatccctt ttgaagatcc tatacaatag
    21361 aaagaaggta aaataatgat caacttaggt attatcggaa caaattggat tactcatcaa
    21421 tttgtccaag cagctttaag cacaaaaaaa tatgaattga cagcggtata ttctagacat
    21481 ttggaaaaag cacaggaatt tggttctcat tatgaagggg atatcgaatt cgcaacagat
    21541 ttgaagactt ttttcaatat tactcatatg gacaccattt atattgcttc tccgaatagt
    21601 cttcacttta gtcaagctaa gcaagcaatt ttggcaggaa aaaatgtgat agttgaaaag
    21661 ccagcttttt cgacgccaaa agaaatggat gaaatcatcc atttggcaaa tgaacacaat
    21721 gtgtattttt ttgaagcagc aagaaatatc catgaatcag gttttaaaaa gattgccgat
    21781 tacttaccat taaaagacga gataatcggt gcaaatttca gctatatgaa atattcttcg
    21841 cgctatgacc aagtattaga tggagaagaa ccgaatatct tctcgactca tttctcaggt
    21901 ggtgcattga tggatttagg tgtttacctt gtatatgcag ctgttgcttg gtttggaatg
    21961 ccaaaagaag tccattattt cccaagaaag atttctactg gtgtagatgg tcttggatgg
    22021 gggatcttac gttatgagaa ttttgatgta tcgatccagc caggtaaaat cggtgattct
    22081 tatttaccgt cagagattta ttttgactca ggaacgctag tgatgaatgg agtcaatgca
    22141 attgaacaag cacaatttca tgatcgcgcg cataaagaaa tcattgattt ggcggtaaca
    22201 gctgcagaaa atccaatggc agatgaagca gaggattttg ccaatgtcat ggctcatccg
    22261 aaagatccag cttggggatt gttgtatgaa gagtggatcg agctagctag aaatgtgaac
    22321 caagtgattt atgatttaag aaaaaatggc ggcatcaaat tcgatgcaga taatgaggaa
    22381 gatttttaat gaacgaattt gtacaagtat ttcccgaaaa ttggcagaaa aaatatgagg
    22441 ataaagggtt tatctcacct tctcttattc aacgagcagt ttttcagcca ctaagtaata
    22501 aacaaagtat agtagcggtt tctcctacag gttcaggtaa aacactggct tatctttggc
    22561 ctctactact aaacgtggaa ccaggtgaag caagtgcgtt ggtcattttt gcttcttctc
    22621 aagaactagc tattcaagta gcagatgttg cacgtgaatg gggaaaagac aaagagttga
    22681 aagtccaatc tttggtgggc ggagccaacg tcaaacgtca gattgagggt ttgaaggaaa
    22741 aaccagaaat cttgattggt acaccaggaa gaatattgga attgatgaaa gcaaaaaaaa
    22801 taaaagcaca tcaagtgaaa acaatggtat ttgatgaagc agaccagcta tttgacgctg
    22861 ggaacagcca aatcattgat caaattcttc atcaagctcc aacagagtat cagctagctt
    22921 ttttttcagc gacagcagat cgttcccttg aaagcattga aaaaatcact gggaaaacgt
    22981 ttgagacaat tgacgtgaca gcagaggacg attctcgaaa aggactgaga cattactttt
    23041 tacgtgtacc gatacgaaag aaagatgact acttgagacg tctcacgcat atagaagatt
    23101 ttcatggtct gattttcttt aatcaactga ctgaattagg cgtaatggaa gaaaaattgc
    23161 tgtatagagg tgtaccggta ggaagtctgg cctctgatca gaacaagcta ctccgaaaag
    23221 cagcgctaga acaattcaaa aagaaaatgg tcagagcact tttgaccaca gatgtggcgg
    23281 ctagaggttt agatattaca ggtcttcctt atgtagtgaa tgcagaagtt ccgttaagtg
    23341 aagaagctta tttgcatcgt tcgggaagaa ctggtcgaat gggtaatgaa ggaatagtaa
    23401 ttacactcgt acaagataat aatctaagag atttaaaacg gcttttacgt ccatcaaata
    23461 taacacttga agagattttt ttatacggag gtaagctgca aactgagcag ccaaccaaag
    23521 aagatgcagc tcctgcagta aataaaaagt atgcgaaaac tttttctgga aaggagcaga
    23581 acccagaata taacaaagaa aaaataagaa aaaaagttaa aaataaatca aaaaaagaga
    23641 gaaataaagg agcaaggcgc aaataagcgc ctttttatgc tatgattatg aaaacgggaa
    23701 caaaattggt tgccagagga ggggttatgt gaaagaacgt caagaagaga tcttgcagct
    23761 attgacagaa aaccaacaag gattgacagc aagtgatgta gctgagcgct taactatcga
    23821 tcgaagcaat gcaagccgat atttaagtga actatacaag gcccatcata ttgtaaaaac
    23881 cgctggccga ccagtcgttt actctttgcc aacggaaaag tcaaaatctg atgaagtgca
    23941 tgtcgactct tctacgcaag tgacttttga aacactcgtt ggagaaaatg attctttaaa
    24001 agtcagcata cagcaggcaa aagctgcgat tctttatcca ccgcgggggt tgcatacgat
    24061 tatttttgga gaaactggta cagggaagtc gatgtttgct gaatgtatgt atcattttgc
    24121 aatcgattca gagatgcttt ctgcagatgc gccatttgtt tctttcaatt gtgcggatta
    24181 tgctcaaaat ccgcaactgc tctttggaca catctttggg atcaaaaaag gggcttacac
    24241 aggagcagct caagatagtc ccggtctaat agccaaagca gacggcggta tattgttttt
    24301 agatgagatc caccgtttac cgccggaagg gcaggaaatg ctgtttactt tcattgataa
    24361 aggtatttac cgtccgcttg gagaaagtgc acaagtacat gaagcatctg ttcagatcat
    24421 tggggcgacg actgaatctt cagaaagttt cttatctacg ttcaatcgac ggattcctat
    24481 ggcaatcacc ttgccgaatc ttgcttcacg ttcactggat gagcgttatg aaatcatctc
    24541 tctttttatc aaacaagaag cgaatcgttt gaatcaacgt atcgatatcg aaaaagaagc
    24601 gattcttgcc ttcatgcttt atgatgcgga aggaaatatc ggtcaagtga aacgagactt
    24661 gaaactagtc tgtgcaaaat cttttttaca ttaccgtact catcatgaga aaaagctaat
    24721 cattcgaaaa gaagaacttt cccttcaagt acaaaaagga ttactgaaaa tcaaggaaat
    24781 accggaacgt ctcgaccgat tcatggacag caaaagtcag tatttgacat ttgaaccagg
    24841 atttgctgat gttgtctggt cacaagatcc agaacgaaac atgcaggtct ataacgatat
    24901 tgaggaaaaa gtcacttctc tttccgaaac cggtgtggag aacattgatc tagagaccct
    24961 catttcaaaa gatgtggatg cttatttcca gacatatgtc aaagaattga ctaaaagttc
    25021 gattcccaaa gatcttttgc cagatgaaat ctggcggtta accaatcaat tgtatgatgt
    25081 ggctgaaaaa cggttagacc gtatttataa tgaaaaagct cgttttgctt ttgctttgca
    25141 tctgcaaagt acattggatc gtgtgagaga aggtcatatg atcgtccacc cagatttgaa
    25201 taacgtacgg aaaaatttta agagggaatt ccaggtagca atcgatcttt caacgatcat
    25261 tgaagaagaa gaacaagttg agattccttt tgatgaaatc ggctttatta gtatgtttct
    25321 ttctatcaat ctaggagaaa gtgagcctgt taaagaaaac aaagtagatg ttctcatatt
    25381 gatgcacggc agacagactg cttcaagcat gttggagatg gcacaagaac tattaggaac
    25441 aaaagtaggg aaagctttta atatgccact ggttatggaa gttcaaacaa tgtatgaaga
    25501 agtgttacaa tatgtcaaaa actatcaaga gcatttgacg aatggcctac tcttgttaac
    25561 agatatggga tcattaaaca ccttcagtga tttgatttat gaagagactg gcattcggac
    25621 gaaagctatc acgatgacaa gtaccatgat tgtgatagaa gcgatacgga tggcaagtgt
    25681 tggaagaagc ttagaagata tttatcaaaa tatccagctt tcctttgaat cgatcgtacg
    25741 tgatcagttc aaagcggaaa agtctgaaac tttacagcgt aaaaaagccg taatcgtgac
    25801 atgctttact ggtgaaggag tagctgccaa attatatcag cgtattatgc cagtgattaa
    25861 tcaaaataag gtagaactga tccagatgca gtttttagaa cgtgaatcat tcaaaaaaca
    25921 catcgatgcc ttattggaag aatatgagat caaagcaatt gcgggaacag ttgatgttga
    25981 ttatcaaaat atcccatttt tttcagccta tgacgttttt gatgatgaaa aactaaatat
    26041 tttaaagcgt atagctgatg atgagatccc gacagctaaa attgtcgatt cacttgctgg
    26101 atcattaagc gatgtctttt ctattgatga actgatccgt tcattgcaaa agacagttca
    26161 gcagatccag accgatttgt cgattatcgt ggaacctgga gtagatactg gaatcgttat
    26221 ccatttagcc ttcatgttag acggattgat caaacaagaa agccatcggc aatttgagaa
    26281 actgtctatt ttctcaaaaa tttatcgttt ggaaatggat atcgttcggg caaacttgat
    26341 ggcactagaa cgaaaatatc aggtaaaaat tccagaagat gatatcgcat ttcttacaca
    26401 aatgtttctt gaaaataaaa taaaaaaatg aacacactaa tcatactgtt tacacactaa
    26461 acatctgtgt gcgcactata aaaaagagct aaaaagcatg aaaacgctat ttcagctctt
    26521 ttttttattg gcatgcttct tgcgttatat aaaagtgtaa aaaaataaaa ggagtgttaa
    26581 aaatggcaaa aaaaacaatc atgttagttt gttcagcagg gatgagtacg agtttattgg
    26641 tcacaaaaat gcaaaaagca gcagaagaaa aagggatgga agccgatatt tttgcggtct
    26701 ctgcctcaga tgcagataat aatttagaat ctaagaatgt cgatgtatta ttattaggtc
    26761 ctcaagtacg tttcatgaaa gctcaatttg aacaaaaact tgcgcctaaa ggtattccat
    26821 tagatgtcat caatatgcaa gactatggca tgatgaacgg agaaaaagtt cttgcacaag
    26881 cagaaaatct aatgaaataa atcaagtatg cagttggggg tataacaacg tggaagatca
    26941 acaaaatcta gaagccatca tggggttaat catgtttggc ggtaatgcaa agagcgatgc
    27001 aatggaagcg attgcggctg ctaaaatcgg tgattttgag ttagcggata ggaaaatcgc
    27061 tgatgcagaa gaatcactta tacaagcgca tcatgcacaa acagacatgt tgacacaaga
    27121 agcacaagga aatcatatgc aagtgacatt attgactgtt cacagtcaag atcacttaat
    27181 gacatctatt gcgtttactg atttagcaaa agaaatcatc gaactttatc gtcgcgtata
    27241 cagcgaataa atacaacttc ttttttgaac ggaagaagaa aaatttttga acggattttt
    27301 tattttgtta taaggagaac tctctttata taaaaaactt ataggaggaa gtaaaaaatg
    27361 aacggactat caagttggat ggagaaatac atcctgccgg ttgccgcaaa aatcggagcg
    27421 caaaaacatt tagttgcttt gcgtgatgct tttatcggca tactgcccgc aacaatggcg
    27481 ggatcagtcg ctgtaatgat caatgcaatt attcgtgatt taccgcaaca gtttaacagt
    27541 acctatgctg acagtttagc agcagacaaa ggaatctttg ccgtattgaa tgtcatcatc
    27601 ggaatcaatg gttttgtctg gaacggtaca ctagcaatcg ccggattgat ctttgccttt
    27661 tcttgggggt ataatcttgc ccgagcttat ggagtaaatg atctagctgg ggggatcgtt
    27721 ggtttagcta ccttgattca aggtatttcc tttggtccag cattatcagc agcattagat
    27781 gtgaatgttc cttcaaatgt cgcagatgca atcaatagtt ctgagattgg tgcaacgatt
    27841 gcagatggca cactgtcagt tggattatgg ggttggctaa aactagatca tttgaatgga
    27901 aacgcttatt ttacagttat gatcatggga gctatttcag tcattatttt ttgtaaattg
    27961 atgcttgcca acattacgat caaaatgcct gattcagtac caccagcagt atctaaagca
    28021 tttgcagcca ttttaccagc gacgatcgct ttatacgtca ttgctattat caattatatc
    28081 gtaggtcgtg tagctgatgg gcaactgatc attgatttgg tgcaaaaata tattgcagaa
    28141 ccattcctag ggttatctca agggttggga gcagtattga tcgtcacagt atttgttcaa
    28201 gtattctggt tctttggtat tcatggatca aatgtattgg caccagtgct agagggaatc
    28261 tggggacaag cacaactaat caatattgat attttccaaa aaggttataa cggaaaaact
    28321 ggtacaccag ccgtgttaga tgcaatcgaa gatggaaaag cttatatgtg ggtccgcgga
    28381 tcgttcgatg cttttgcatg gtttggcgga tcaggcggaa cgatcgtctt actgatagct
    28441 atcttgattt tctctaaacg tgcagattat ctaacagtag ctaaattatc cattgggcct
    28501 ggtatcttca atatcaacga accagtgatg tttggtctgc caatcgtatt gaatgcaatc
    28561 atgtttatcc cattcttgat tgctccagta gtagcaacag caattggatg gacagctact
    28621 tatcttggcc tagtcgctcc ggtatcgcag caagtcacat gggtagtacc gccgttctta
    28681 ttgtcattct tagcaacagg agcggattgg cgggcaccga tcgtaacatt agtatgtatg
    28741 gtcgtgactt tcttgatttg ggcaccattt gtcatctctg caaacaaaat ggaccctgcc
    28801 gcaggcgaac aacaataaga tgaacgtgag gagcgggacg ctttaagttt cgttcctcat
    28861 aatgaatttt cgaggaggaa ctgaaatgat tacaattgcc agtgcaatgc aacaagatga
    28921 aatcaaagaa ttgttagaag gatacaatga agaaggaatg acttttacat ttaaagaaaa
    28981 acaaggaatc aagctgttct ttgaaacaag tgcagaagat ccggaagttg cggctaaaaa
    29041 agcaaaggaa ctaatcaaag cacagccttg gggaacagtc ctttattttc aatcaacagc
    29101 tgtttagaaa atggtttaaa aagataggat ggttgagatg ataaaaaacg gtttattttt
    29161 atgtagtatt ggttctttga tcgtgttgta tagtttgaat ccacattcgc aaaggtatga
    29221 tttgtatagt atggtcacag gtctttttct aacaggatta ggaatctatt tcttcatgaa
    29281 ggggaaaaaa agagaagaag caaaggagaa aaataactaa tggaaatcac gaaaaaatta
    29341 aatattccag catcgttttt ttacgataaa gttatggact ctgtcctttt cgatgtacgt
    29401 aaagcgaccg gcaaatcagt aactagaaaa cagctgaaaa atttggagta cgtcaaacaa
    29461 ttctcgcaaa ataaccgggc tcgcataaaa atcgaagaag tcattgaaaa ccagtcttat
    29521 aagtttcgta catcgacaac gaagaatgaa ttcgtcgttc attatcaaat caaaccattg
    29581 gacgattcga cctgtgaggt tcattacaca gaaaaaatgg agtcttatgg catgcttcaa
    29641 aagttgaatg atatgctttt aggaacaatc ttgatgtatt ttaaacggag acgtttcaaa
    29701 aaaatgctag atatgatcga agcaacgtat taaatcaatg aaacatggta ctatttagtt
    29761 attgaaaaat gaagtaagct agaaggaatt tttcatagga agatagatct ttcctgcgaa
    29821 tcctcactag cttttttgta ggaaggggca gcaaaatgac aaacaaagta agagagctag
    29881 gtgtatcttc gattgaggaa atgtttgatt tagccactta tgcatttaat ggggcagata
    29941 cacctgaaag gcgagaacgt tttcgtacac ttgcggagaa ttcttggaat tacggatttt
    30001 ttgatgagga ggatcggcta acaagtcaag tcatggcgac cccttttcca gtgaattttt
    30061 acggacaaga gtacctaatg gccggcattg gctatgttgc ttcttatcca gaagcaaggg
    30121 gacaaggcgg gatcaatcag atcatggaaa agatccttga agattgccgt gatcgtaaag
    30181 taagcttatc ttatctggcg ccattctcct atcccttcta tcggcgctat ggctatgaac
    30241 aatcatttga taaaatcagt tatcaactaa acagtcgtga tgtgccgttt atcaaaaaaa
    30301 aatctggaaa aataaagcgt atggattttg aagatgcaaa agctgcaatc agaagaattt
    30361 atgaacagat gccggaaaac caacgagctg gtctgaagcg cgaagactgg tggtatacgt
    30421 ataaattcaa gcaaaaaggc aattaccagt ttgctttgca ttttgatgat aatgaggaag
    30481 caacgggata tatcgtttat cagcttgcaa cgtcttcctt tattattgcg gagtggggat
    30541 ttttggatca tgatgctttt tgcagccttg ttcgcttcgt aagttctcac aatggtgctt
    30601 ttgaaacatt tgaatattca tgcggctacg gcggtaatga tcaaaattat ctattagaaa
    30661 atccatttgc ttctgtaatg atcacacctt atatgatggc gaggatcgta gatatttctt
    30721 tgtttttgga aaattatcca tttaaaaaga gacaagctgc atttgcccta caaatagaag
    30781 aagatcatta tgcgaaatgg aatgaaggaa tcgtggaagt aacaatcgaa aatggaaaaa
    30841 atcatctctc aaaagtagaa caaacaaaac tcccaatcgt tcgaggaagt atccaacata
    30901 tcacgcagct attattaggg tatcgtaaag tggaagagtt ggtattccaa gaaagaatac
    30961 aggtgacaaa agaatatgaa gaaacgttaa gctcaatctt gccacagcaa cagccaattc
    31021 ttaatgacta tttttgataa aaaacgggtg atgacaatat ttttgtcacc acccttttgt
    31081 ttttcatttg gcatttgaag gaaaatgtta aagtaaatcc tcttttttcg taaatttgaa
    31141 ttttttgttt tcttttgttt tagggttttc ttttttgtgg tcttggattg cttctttcgt
    31201 aatcttttcc cgattttttt tagatgaatc taagcgttct gcgtatactt tttcttttgg
    31261 cttatcattc attggaaagg acctccctac attatttcat tctacctcta gtttatcatc
    31321 tgttaaggac tagtggaaac gttttgccta acttataagc tgattttttt agcagataag
    31381 cttgcaagta aaaaacaaac aagctacaat tgatttattg aaattgttcc tgtagctcag
    31441 taggatagag caatcgcctc ctaagcgata ggtcgctggt tcaattccag tcaggaacgt
    31501 ataaataacc cctgtatcct ttgcggtaca ggggtttgtt ttgtatttgt gccaaaaatg
    31561 tgccaaacta gttatcattt ttatataaac tatcgaacac agtattgatt ttttctttat
    31621 cctgatcttc aagctctcga acaatatgaa gataagtaga cattgtagtt tctaaactgc
    31681 tatgtcctaa acgtttcgat acgctaagta tatttactcc ttgataaagt aaaatagatg
    31741 catgcgtatg tcttagtcca tcaataaaca gtcgaagaga aaatagggaa aaattgatta
    31801 ctaaagaaaa acttactagg tcgacggtgt agttgatttt catacttcaa tagattcgaa
    31861 ttaaacgatt tcgattggct tataccagtc ctatccaacg aaagatatat cgttcttaac
    31921 tctagcggta taacttgaag ctttacgtaa agccaatggg aatgaactgg agatgacttt
    31981 ttattatttt tagtaatagc tgatgggtta atacttacaa ctttcctttt caaagtacca
    32041 tataaaaaaa cggtggggtt gtttagcgaa ataaaggatc taagccaata gcttagatcc
    32101 tttattctat gctttatat
//
LOCUS       DADGHT010000025        31317 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.025, whole genome shotgun sequence.
ACCESSION   DADGHT010000025 DADGHT010000000
VERSION     DADGHT010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.025"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(537..899)
                     /locus_tag="JX887_001001"
     CDS             complement(537..899)
                     /locus_tag="JX887_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257008.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(973..1353)
                     /locus_tag="JX887_001002"
     CDS             complement(973..1353)
                     /locus_tag="JX887_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAX1257009.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1435..2610
                     /locus_tag="JX887_001003"
     CDS             1435..2610
                     /locus_tag="JX887_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAX1257010.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2687..3271)
                     /locus_tag="JX887_001004"
     CDS             complement(2687..3271)
                     /locus_tag="JX887_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1257011.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3472..4470
                     /locus_tag="JX887_001005"
     CDS             3472..4470
                     /locus_tag="JX887_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAX1257012.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4582..5091
                     /locus_tag="JX887_001006"
     CDS             4582..5091
                     /locus_tag="JX887_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAX1257013.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(5121..5780)
                     /locus_tag="JX887_001007"
     CDS             complement(5121..5780)
                     /locus_tag="JX887_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAX1257014.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5782..6546)
                     /locus_tag="JX887_001008"
     CDS             complement(5782..6546)
                     /locus_tag="JX887_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAX1257015.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6554..7231)
                     /locus_tag="JX887_001009"
     CDS             complement(6554..7231)
                     /locus_tag="JX887_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAX1257016.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7268..8653)
                     /locus_tag="JX887_001010"
     CDS             complement(7268..8653)
                     /locus_tag="JX887_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAX1257017.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8863..8947)
                     /gene="ffs"
                     /locus_tag="JX887_001011"
     ncRNA           complement(8863..8947)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="JX887_001011"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8970..9485)
                     /gene="tadA"
                     /locus_tag="JX887_001012"
     CDS             complement(8970..9485)
                     /gene="tadA"
                     /locus_tag="JX887_001012"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAX1257018.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9592..10449
                     /locus_tag="JX887_001013"
     CDS             9592..10449
                     /locus_tag="JX887_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAX1257019.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10530..10865)
                     /locus_tag="JX887_001014"
     CDS             complement(10530..10865)
                     /locus_tag="JX887_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257020.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10932..12302)
                     /locus_tag="JX887_001015"
     CDS             complement(10932..12302)
                     /locus_tag="JX887_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAX1257021.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12380..12916)
                     /locus_tag="JX887_001016"
     CDS             complement(12380..12916)
                     /locus_tag="JX887_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1257022.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13225..14706
                     /locus_tag="JX887_001017"
     CDS             13225..14706
                     /locus_tag="JX887_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAX1257023.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(14809..15516)
                     /locus_tag="JX887_001018"
     CDS             complement(14809..15516)
                     /locus_tag="JX887_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAX1257024.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15595..15933)
                     /locus_tag="JX887_001019"
     CDS             complement(15595..15933)
                     /locus_tag="JX887_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAX1257025.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(16044..17006)
                     /locus_tag="JX887_001020"
     CDS             complement(16044..17006)
                     /locus_tag="JX887_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAX1257026.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(17021..18352)
                     /locus_tag="JX887_001021"
     CDS             complement(17021..18352)
                     /locus_tag="JX887_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAX1257027.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18360..19040)
                     /locus_tag="JX887_001022"
     CDS             complement(18360..19040)
                     /locus_tag="JX887_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAX1257028.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19259..19738)
                     /locus_tag="JX887_001023"
     CDS             complement(19259..19738)
                     /locus_tag="JX887_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAX1257029.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(19865..21544)
                     /locus_tag="JX887_001024"
     CDS             complement(19865..21544)
                     /locus_tag="JX887_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAX1257030.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            22092..23594
                     /locus_tag="JX887_001025"
     CDS             22092..23594
                     /locus_tag="JX887_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1257031.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            23607..24269
                     /locus_tag="JX887_001026"
     CDS             23607..24269
                     /locus_tag="JX887_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1257032.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(24370..24573)
                     /locus_tag="JX887_001027"
     CDS             complement(24370..24573)
                     /locus_tag="JX887_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAX1257033.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(24684..25868)
                     /gene="iadA"
                     /locus_tag="JX887_001028"
     CDS             complement(24684..25868)
                     /gene="iadA"
                     /locus_tag="JX887_001028"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAX1257034.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(26025..27764)
                     /gene="yfcC"
                     /locus_tag="JX887_001029"
     CDS             complement(26025..27764)
                     /gene="yfcC"
                     /locus_tag="JX887_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAX1257035.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(28537..29151)
                     /locus_tag="JX887_001030"
     CDS             complement(28537..29151)
                     /locus_tag="JX887_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAX1257036.1"
                     /translation="MSLCYFDYYHQLEEKLRIEETLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(29757..30134)
                     /locus_tag="JX887_001031"
     CDS             complement(29757..30134)
                     /locus_tag="JX887_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257037.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(30434..31315)
                     /gene="galU"
                     /locus_tag="JX887_001032"
     CDS             complement(30434..31315)
                     /gene="galU"
                     /locus_tag="JX887_001032"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAX1257038.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         9334 a         6497 c         5220 g        10266 t
ORIGIN      
        1 cgattcgttt ttggctgccg tagcaacttt tatatcatat cagagagaca agcgattgtc
       61 aactcttttt taaaagtttt tttcgatttc gtttttcgaa atctttcagc aactcattta
      121 tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc gatagaatca
      181 agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcgt tagtaacatg
      241 tcaataacta ttttttaaat tttttagaaa tgtgatataa catccacttc agaatcaacg
      301 ctgttaaatt tatcatgtat ttcttccttg gtcaactata aattaagcat tactttgtga
      361 aatgattttt cgatcaatta ttattattcg ttatacaacc gttttcaaca tattttgaaa
      421 ataaaatgca ctaaaaaact atctttagca gaacatttca ttgtattttt tggaccaaac
      481 aataaaaaaa gaagtttgaa aaaaattcaa acttctttgt tcgcttaatc tgtattttag
      541 aagaaaggca ctccctctac ttcgtaagtt ccaagaacag agcgcatttg acctggttct
      601 tcccaaatat atccttcgcc taattcttct ctttgattct tttgttcagt ttcaaagaca
      661 aacaacggaa cattttcctc tttaatatgt gtatttgtca attccatcaa actaatcttg
      721 ctaacatcga tatgaactat ttcttttaag aaattaagta tattcgctaa accagtcttt
      781 ccttcagaaa gttccgctaa cgcaaattcc aacttgtcat caattgaatg gaccaaaaat
      841 tttttagtac catcctccaa atgcaacata attgtaccag caactctttt gcttgccaaa
      901 atttccacct cgatcaactt gttctatggc ttacataaaa attctagcac attttcagaa
      961 aaaatacact ttttatttct tattttcttt ccgttctagt tcagataatg cttcttctat
     1021 ccaaataggt aactgctccg caatagtggt aaatccgatc ttacgatttt tattcgtgaa
     1081 ataccttttt ctgcgatatg gaacagctgg atttgttttt tctaacgttc ttaaagataa
     1141 actgattttt ttggaatatt catcaatgtc gatgatctga actgttactg gctgtccgac
     1201 ttttaacaat gaatggatat ttttcgtata accggattgt acttctgaaa catgaataag
     1261 tccttgcgtc tcgttatcaa gagaaacgaa tgcgccataa ggctgtatcc ctgtcacttt
     1321 tccttcaatt atttgtccaa ttttataagt catctacttc cctctcttcg catttatcat
     1381 tatactgtaa atagctcaaa aaaagaagcg acgaaaatga ctggaggtct taagatgatc
     1441 gaatttgata aacagatttc aagaaaagat acagaaagtg taaaatggga cgcaattgct
     1501 gagacatatc aaatggatga cttacttcct ttgtgggtag cagatatgga cttcttgtct
     1561 cccggtgggg tagctaaagc gtttagtgaa tacatcaaac atggaatctt tggttatgcc
     1621 actctgtctg ataaactata tcaggctatc attcattggg aacgccaaca ccatgctgtg
     1681 gagttgacga aagaaaatat cgtttttaca agtggtgtgt taaccagttt agctgcagca
     1741 gtacaaactt ttacaaaacc aggcgattct attttgattc atgacccagt ttatcctcca
     1801 ttttcctcta ttatagaaac aaatcaacgt cacatcgttc gaagctcttt gctagaaaaa
     1861 aataatcatt tcatcatgga cttgtctgac atggagaaaa aaatcgaaga aaacaatgta
     1921 aaagcaatga ttttatgcaa tcctcacaat cctggagggc gtgtttggag caaagaagaa
     1981 ttgaaacagt taagcgaatt gtgtttaaaa catcaagtga ttctgtttag tgacgagatc
     2041 catcaagatt taactttatt cgatcataca tttacttcca tgctaacgat tgatcctaat
     2101 ttagatgatc tactagttgc ttttacttcc gcaaccaaga ctttcaatct agctgcaatc
     2161 aaaaattcaa tggtatttat caaaaatcca gagatgaaag ctgattttga aaaacattta
     2221 gtgatgaacc aacagcacga aatcaacact tttggactga ttggaaccca agcggcttat
     2281 gagacgggtg gagaatggtt aagccaactg attccttatc tagaaaaaaa tgttcaaaca
     2341 gttaatcagt tttttgaaca gtatcttccg aaagtgagaa taatgaaccc tgaaggaact
     2401 tacttaatgt ggttagattt taccgcctat atttcagacg accaagaatt ggagaacact
     2461 cttgttcgga aaggaaaagt cgtattaaat cctggcatca cgtttggtcc ttccggtcat
     2521 gggcatatgc gcttgaatat tgcttgtcca gaagaaactt tactggaagg acttaatcga
     2581 atcaagtatg ctttagagac aatcgattaa atcatttatt caaaataaaa ggacgagacc
     2641 ttactaggtt tcgtcctttt tcataattac tccgtaccat accaaactat tctgaaattt
     2701 caattgtttc aatcactaca tcatgtacag gtcggtcttg tggaccacgt tgtacatttg
     2761 cgatttcatc tactgtgtcc atcccttcta gtacatgtcc aaagactgta tgtcggaaat
     2821 ctagccaagg agttccgcca cctttatacg cttcaatgat ttctgatggg aatccagcac
     2881 cttctagttg tccaagcata ttagctggca catttgtgtt atttacaata aagaattggc
     2941 ttccgtttgt gtttggacct gaatttgcca tagataaagc tccgcgaagg ttgaacagtt
     3001 cacgactgaa ttcatcttca aaactttcgc cataaatact ttcgccaccc attcctgttc
     3061 cagttggatc gccgccttgg atcatgaaat caggaataac gcggtgaaaa atcacgccat
     3121 cataataacc ttttttggaa agttcaatga aattttgaac cgtcttcggt gctagttcag
     3181 ggaataattg aacagtaatg tcaccacggt ttgttttgat aacagctttt ggtccttttt
     3241 cactttttaa atctagttgt gggaatgcca tattgtttcc tcctaatatt tgcatacttc
     3301 ataataataa taacataata cctaacctct cgtaaaaata ctagatttgt tttcttttat
     3361 ttttcatcac tagatacatt ctataactta ccgtttcgat ttcgaattca aacatttttg
     3421 agaagcattc tcaattaaat tctgatatag tgtgaaaagg gaggaatttt tatggaaatc
     3481 tatgacatta caatcatcgg tgcaggtcct gtagggatgt ttgccgcttt ttacgcagga
     3541 atgcgccaag ctaaaacaaa aatcattgac agtctacctc aacttggtgg tcaattagca
     3601 actttgtatc ccgaaaaata tatttacgat attcctgggt atccagcaat aaaagcaagt
     3661 gaattaatcg atcaattaga aaaacaatta actactttta accatacatt ccatttaaaa
     3721 gaagaagttc tctcgcttac tcgtgaagac gaagttatcg agattactac aaataaaggc
     3781 atccattatt ccaaagcagt cattttagct ttaggaaatg gttcattcca gccaagaaaa
     3841 ttgaatttag ataatgctga atcatttgaa aaccacggat tggattattt cgtgaatgat
     3901 ttgatgaagt atgctggaaa aaaagtcgct attgctggag gtggtgattc tgctatcgat
     3961 tggacgttga tgttagagcc tattgcaagc gaagtttact tgattcatcg tcgcccggaa
     4021 tttcgtgcgc acgaacatag tgtatcacgc ttgaaatctt catctgtcaa cttgcttact
     4081 ccctatctca tcgatggatt atcaggcaat aatggggaac tgacagatat ccggttaaaa
     4141 aaagtgaaaa gtgacgagac gattgatttg atgattgatt ctctgatcgt caattatgga
     4201 ttctcttcta atttagaaca tctttcttct tggggacttg atagtaccag aaatgccatt
     4261 actgtaaaat cagatatgtc tacttctatt ccaggcgttt atgcagctgg tgacatctgt
     4321 acctatgaag gaaaagtgaa actgattgct actgggctcg gtgaagcacc tactgcagtg
     4381 aacaacgctt tacactatat taatccaaag gaacgaactc agcctggtca cagcacaagc
     4441 ttatacgata aaaatcttcg tcctagttga ttttttatat ctctttgcat ttcaagttaa
     4501 acccgaaagc agtttcttgc atttttttca tgttccgtta acatgaaata gagaaagaaa
     4561 aaataaaggg ggagcaataa tatggtcgtc aaaactgaga ctttagaaga aaaggcaaga
     4621 gaactattga aggaacgtgg cgtaactgta gaagatatcg cacaacttgt catgttttta
     4681 caaaaagact atatttctga tttgactttg gcggattgta ctgaaagtgt caacagcgtg
     4741 ctaacaaagc gtgaagtaca taacgccatt atcactggaa tccaattaga tatattagca
     4801 gaaaagaaaa aattgatgag tccgttgcaa catattatcg aagatgacga aggcctttac
     4861 ggtatcgatg agatcctagc cttgtcaatc gtgaatgttt acggtacgat cggctttacg
     4921 aattatggtt atatcgacaa ggtgaaacct ggtattttaa aagaactaaa cagccacgat
     4981 ggcgttcatg tccatacctt cttagatgat atcgtcggag cgatcgccgc tgctgctgcc
     5041 agtcgattag cacacaaaga accagaaaaa agaagtcgcc ttactcaata attcaacaaa
     5101 aaaagaaaga aaacgtctat ttagacgagt tctttctttt ttgtttgttt caagctattt
     5161 tttcctaaga aaagaaaaac agcaaaaaat aattctaata atacaaaaaa taagataaag
     5221 ctatgcatga aaaattcttc tggaagtaca ttgatgattg gatcagtaac gggatcgaat
     5281 aaccagtcat cgttgttgaa aaacgtttca tgaaaaagga taaaaaagcg atcaaatcct
     5341 atcatcatga aaaaaccgaa aacaactggc agtaacatgc cgatttgaaa cggacgaatc
     5401 aaccgccaaa gccgatcatt cttttgcaaa tatttgataa acaaaatact cgggatcaaa
     5461 gtgatgaaaa acacagcata atccactaaa aacaaaattt tcacttcata aaagtgatgg
     5521 gctccgctag cagaaactgg gaaatctggc aagctgagga tggttttgaa gggattattg
     5581 agataattca ttaggtgatc aaaatttttc agtaacgtct cttgatctaa agaagtataa
     5641 tccaaaattt gcaaatgtcc gatatcaaat acgtatagtg gtcgaaagtt gatcgtcaca
     5701 ccaactgcca gactgatcag tgtcagaaat aggctgaaca atccagcata ttccatccac
     5761 tgccatctcg aatttttcat attagaagct ccattcatcc agtgattgtt tcacataggt
     5821 agctgggata ggcaacccag gtacatcttc ttcttttgta aaacctgata aaacgagcaa
     5881 agtatctata ttattgcgta tcccagcttg gatatctgtt tcatagttat ctccaaccat
     5941 gattacttct tctttttgca gccctaatac ttcaacggct ttatccataa tgatggcttc
     6001 tggttttccg atgtagatcg gcggcgtttg ggttgctgtc tctacaaaag agatgactga
     6061 ccctgctcca ggaagaaggc cgcgttcagt aggtatattc ttatctgggt tcgttccaat
     6121 gaaagtagca cctttttgaa tagcaagtgt tgctttaact actttttcat aggtcagata
     6181 attatctaag cctaccacta catagtcagg agcctcttct tcccatgtaa atccggcagc
     6241 taaaatcaag tcaatcaatc ctgcttctcc gataacatag acttttttcc cttttccatc
     6301 tgctttcata aaatcgattg ttgccaaagt agctgtgtag actgtctctg gagctacatg
     6361 aatgtcaaac tcatctgcta gacgattagc tactgtttct ggtgacttag tcgtgttatt
     6421 ggtaacaaac aagaaaggta attttctttt ttgcaattct tccacaaatc gtttaccggc
     6481 cggtatgggt tgtgtcccac gataaatcgt tccgtctaaa tcaattaaat atcctttata
     6541 gtccattcat ccactactct tccctttttc tgatcgtaaa tgctgttttt gttttttcta
     6601 cttgtttagg ttgttcttgt ttttttactt tttcagaggt ttttgctgac tctgtttttc
     6661 gatttttaat aaccggtttt ttgcgattag atgcgactgg tccttttttc tcatcgatat
     6721 acgcacgatt atggtttttt ttcttttttc ggcgctgagt tgtcttttct tttttaccgc
     6781 cgattctctc gatgacaaaa tacgcacaac caaaattgca atattcgtaa agatagtctt
     6841 ccaaggaatc gattcgctga tctggatgcg cccgtcgatt atccgcttgg aaaaatcctt
     6901 ttaggcgtag ttgttcataa ccccaatctc ctacgatata atcatatcgg gctagtacat
     6961 cactgtaacg ttctccaagc ttttctgcat taaatccttc acgataatcg gacacaagcc
     7021 gataatgtct ttcacctatc aaaaaattac tgtcatctaa cagtgtcact agctcgcctt
     7081 tgactttttc tgctttaggc tcctcaacga tttcttccaa agcagctgtc agttcttcgg
     7141 tgactgttgt ttcctgttca gctgatgatt ttttcttagc aatttctgtt ttatgctcaa
     7201 cgttctgctg ttcattttgt tttgcagaca tgcgttcacc acctatcttt tttattatac
     7261 cttgttttta tttgattggg tagtgagctt tcaagtaatc tcctaccaca cttcggataa
     7321 attcagggaa caaaaattca ttttttccag caatctcaat cgttggaaaa aatggaacaa
     7381 acatcaaatg atctacggta gtaaaagtat aatttttatt cagatcgatt ggcttgttct
     7441 tccaaaagac ttgatggtta atagaatcat atgtgattcc attatagacc atctgcccaa
     7501 aaatcttacc gcgaaatccc attcccttca taggatagtt acgtaaaaag ttacgatttt
     7561 tttctatttc taaaactaag cggatcagat catttccacc caatgtgaca tttaacaagt
     7621 gcatcggatg cggcaacgca gtgtgaagct gatcctgatt gacccgccct tttggaattt
     7681 cagttaaaaa cagaccactg tttaatattg ctgcttccgt ctttcctcgt tctttcaccg
     7741 cctcaaaggc tacttggata aacgaatgct cattgaagat atctagactc agagaaaatg
     7801 gcaaatctgc tacttctttt tcttttaata attcatgccc acgttctaga taactattta
     7861 tttcttgttc atcttctgta aaagctgtca ttgtttcggt agggatggct ttggctgaat
     7921 gcttaaggat ttttttctct tcatcgatgg ttaaatggac ttcaccgaca tactgcccgt
     7981 actttccagc ggctgctatt tggacatcat tgattacgtg accttctctg aataaatgat
     8041 gggtgtgcga tcctaaaata acatcaattg ctggtatttc ttttgcaatt tggaaatcat
     8101 cctgaatccc gagatgactc atcaaaacta aaacatccac ttgtgaacgt aaatcttcga
     8161 ctaattctgg caaaatatca taaggattcc gtatgtccca gccattcgga ttataagtaa
     8221 gcggaaatgg agcagtaaat gcaattagtc cgattttcgt ctggtgtttc gttgtaatga
     8281 ttttatatgg tttcgtccat gccggtggct ggagcgtatt tttatcgaat aagttatcca
     8341 ggatgatatc aaactcagca tgatcgtata aatgattcaa ctcttctttg gaatttccta
     8401 cgccttcatt gtttcctatc gtcgctgcat cataaccaac ttcattcatc agcaagatat
     8461 tttcctgtcc attcgttgct tctgacaatg gatgccaacg atccacaaaa tcacctagat
     8521 ctactgcaat cgttgtcgtt ttttctttct tttcgttttc tcgtttacgt tgatccaaaa
     8581 accttctgat ccttggccaa ttttctaaat gagaatgcag atcattcgta tgtaaaatca
     8641 ctattttttc catgtaccct ctcgcctctc tttatcttta tcataccata ggcagctttt
     8701 tcttccattg aaacaagctc tatttcagag tttttcctgc cttgaagcaa attgtataag
     8761 tacaatattc gataaatcag tctggctaaa aaatcaggaa cattcatttt tacagtacta
     8821 taaaaataaa aaaaacagac ccgaaagtct gttgtcgttt cattataatc agacacatgg
     8881 cggaacctgc ttagtgctgc ttccttccag acctgacacg cttcacaagc ccaccattgt
     8941 cctagccttt cggcaaagaa tagtatacct tatttttcat tcgttgacca gtcttttttt
     9001 aatttctttt ttcgctggcg gagctttcgg aaaaagtcag tcaaaatcat cccacattcg
     9061 tcttctaaaa tgccaccttc tacatatgct tggtggttaa accgctcgtc ctccaaaaga
     9121 ttcatcaagg taccggctgt tccgcctttt ggatcatacg cgccgaaata aacttctgct
     9181 acacgagaca aaatcatcgc gccgctgcac ataggacaag gctctaaggt aacaaaaagt
     9241 gcagcatctt ccaagcgcca gcttcccact ttttcacagg cttccttgat tgcaagcatt
     9301 tctgcatgtg tagtagcatc ttgcgtggtt tctctaaggt tatatcctct tccaatcact
     9361 tttccatcca atacaaccac tgctccaatc ggaacttcat gaagcatttc tgctttcttt
     9421 gcttctgcca atgcaaggcg catccatttt tctttttcta ctgcatcaag atttgtattt
     9481 accaattacc cttccctgcc tttgtttttt cttgttttac tttagcatat gataaaaagg
     9541 ctgtaactaa cttttttttc tatggtaaaa taaatacaag aggtgaacaa gatgaaaatg
     9601 gataaattac ttgctcttta cccacaagca cagaaaaaaa actctccagc atcagaagcg
     9661 gatatccttt cttttgcaat tgatgatgct tttatctgga tcaaacaaga ttcattatct
     9721 caacaagaaa ccagcctttt gaaagcgtta ttccctgtaa tcaacgatca aaaaaaacac
     9781 ccatggtatc actatctttt taaagatgct tcttgtgttc aagaaaaaag ctttcgtttg
     9841 atccagcttc acgtcgaatc aaaaggagaa ttcttaaaaa aagaatggca agatactatt
     9901 ttggaattat ttcgctattc tgctgatttc tttttttata cagacacaga tgcgctctta
     9961 gtcgaacaaa taaaccgtga ttatcttgat gctactgaaa tcaacggtat ttttctatct
    10021 ttagatgctg attttgatac gacaacgtct gtattcgttg gttctttcca ttcacctggc
    10081 accgacctcg tccctttgtt tgctgaagaa agaaaaattt ttttaacaga gcaaaacaat
    10141 ctttatactc acagccgtac tttttctatg caagatgtgg ctttacatta ctatacaaaa
    10201 gatactgtaa aagatagtaa gttgatcaaa agttacatag aactgatcaa acaaaatgaa
    10261 atggaagtga tcattcaaga attatggaat gaattaggca atgtcagctc tgctgcaaaa
    10321 acactgtttc ttcatcgtaa tactctaaaa tatcgaatcg aaaaatttca agaacagtct
    10381 ggtttcaatc taaaaaaagc caacgattta ctgttttgct atcttttatt gcttcatgaa
    10441 cataattaaa gatagattaa aggggttgtg acaataattt tgtcacaacc ccttatttcg
    10501 aatgaatagt gttcaaaagc tagtttctct tacatcattt tttcaacaaa atgcattagc
    10561 cggtctttta catcttcggt tgaatctttg attgaatcac cataaacaga gattttcttt
    10621 tttcctgatt tgatttttgc taacattccc atcaaagaat ccaagtcact atctgaaaga
    10681 ccatctacga tttctagtaa tttttcattt ccatcaaatt tgtcatagac gaattttttt
    10741 actttcgtcc gagtagtcat atgatggatc ttttccatta cttttcccga tacaacgact
    10801 gctgtcgcta cactggcagc ggctgctacg cttaatccga ttgttacttt tgttgatgtt
    10861 ttcataagta tcagctcctt tttatctatc tccatcatag catagacaaa aaaataaacg
    10921 aactaatcca ctcagtgaaa tctcaatcct ttagggaaaa agttctttac tgttcctttt
    10981 acttgtttcc caaatccgac aggtatctta tctaatacta gcaaaaccca tccttgattc
    11041 ccatcacgtt gaaatgtttc tcctgctgtg taagattgcc attccttttg agtgatcggc
    11101 aagcaaggta tattctctat cttttttgta gcaagcgcta atgcatagct aggttcaaat
    11161 cgattctttt tgaaatctcc taaatgcaaa cctgtacgta cgacttttaa accatcgaga
    11221 gaaggggcta actcaggaac ttcccaaaga tggtcgttga acactaaaag tcttccagta
    11281 gcttcataat gaaaatcatt tgaaaactcc gtccagagtt tttcctgctc ttttgtcatt
    11341 tgcactttac ttttttttcg tgtcttcttt tctttatgca tctgattttg tccatgaaaa
    11401 gtcagctttg caacaaaatg tccttcaccc tgatctttat gaggccatat acgtattgtt
    11461 ttttccaaac cagctacgct tccccattca gaacgtcctg aactaacgga ttgagtcaaa
    11521 ggaatctcct caatcgttac tggataattt tctacaagcc agctaatgat ctcttcattt
    11581 tcttctggtg caaacgtaca agtcgaataa atcagttgtc ctttattttt tagcattttt
    11641 attgctgaag acaaaatctc ttgctgacgt ttttgacagt atagcggaga ttcttctgtc
    11701 cactctttta ttgcatttgg atcttttcgg aacattcctt ctcctgaaca aggagcatca
    11761 accacgatcc gatcaaaaaa gcccgaaaaa tgagggacaa gttctgcggg tgcatgattt
    11821 gtcactattg cgttcgaaac tccccatcgt tctatatttt ctgataaaat cttcgcacgt
    11881 ttcggaaaga tctcattcgt cactaataac cctttcccct tcatttgagc agctaattgg
    11941 gttgatttac caccgggagc cgcacacaaa tccaaaactt tttcaccggg ttttgctgca
    12001 gcagctgttc caacgatcat tgcacttggt tcttggctat attcataccc agcttgatgg
    12061 aggaaagact ttccattgac agtgccaaga aatccctcat tgctgtaggg agcgggttgt
    12121 aattcttcgc tatggtaagt ttggaccatg tccaatcctg ccggttttag tggattccac
    12181 cgaaatcctt ttttcacgct tccttgttca agcgcagaaa aaaaatcgga tgcttcttcg
    12241 cctaaaagaa gacgatattt tttgataaat tgctgtggta acgttgtcgc ttcctccttc
    12301 attccaatgt ttcgttagac attttacaat cttttttacg aaaaataaag gtggctgatc
    12361 tactttttca tgttgctgcc taaggtgact gttcctttaa gatattttcc aagtattcat
    12421 ccgtcacctc gtttttatcc caaacagcgt tcatcatttc aagaaaatct tgagaagaat
    12481 catctgagcg caaacttccc aatgcattaa gccataccaa ttcaagcgac ttttcttctt
    12541 tgatcttcgt gtgacctttg acatatgaga aaaatggccg cttaaatagc gaatccatgt
    12601 ctaaatcaga ttttgcaatg atttcacgaa tactttcatg gatagaaaaa aaatctttca
    12661 ataagtagac aatgcttaaa acatcatcgg aactgcattc agctaagtag ttttcaaaat
    12721 aaacagtgat ttcttctaat atcttctctt ttaacccgct gattgatttg aaatgtgtat
    12781 aaatcgggta tgtagaacaa ccgcagaact ctgctaactc tcttgcagta attgacttca
    12841 ttccatattc ttccacgtat accatacttt tgaacagcaa atattcttta ctataatttg
    12901 ttactctccc catcattctt acctccgtct cttttcatct acccataaat aaataacata
    12961 aataattcta aaaatattat tgataattat caaaacatat ttagttatat ccattaaaaa
    13021 tcaatttttc cgccttaaaa acaagaatat cttgacaaaa taccctagga aataaacaat
    13081 agaataaaca aggtaacaaa aaaattaaat aacgttatat aaaaaagaag gcgacactct
    13141 gtgagaataa cacagactga aatgactttc cactcacagt ttttgtctaa ctatatacaa
    13201 aaacagaata aaaaggaggt atttatgcta attgaagcaa gaaaaaaaga gttacttgtt
    13261 ctacaaatgg tcattcaaaa aaataattgt tctttacaag aattatccaa tgacttacat
    13321 attccaaaac ggacaatcaa agaactgatc cgaaaaataa atgtatcact caagcaattt
    13381 ttattgattg atgaatttat ttattctaat cataaaggag agatccaaac caaagaaacc
    13441 gatcaaacta aaaagttagc tgttttttct aagttaaaat tatgctacct aaaagaatcc
    13501 aatcgtttta actatttgat gttactaatc aattatccac aaactgctgt accaaaaaaa
    13561 tatttacttg aacaacttta tatatcgccc tcctatctcg aaaaactgac aaaacagctc
    13621 aatcattcct taataaaatt ccatttacgg atcctatctg taaaaaattg ctgtactctt
    13681 gaaggaaatg agttatctat ccgtctctat ctttactttt ttctttcaga tacatttgga
    13741 ggtaacgatt ggccattttc ctcacttgaa ttaaatgcac taaaaatgaa cagtacagat
    13801 gagcaaatag aaaaaatttc aaaacaagaa aaaaatatct acttgctgtt aactttattc
    13861 atattacgaa acaaacaaca ggcatatttt ccaaaaactt cttctgaaat cactgaattg
    13921 atggacttat tgcagcatac acatgattat tcagaatact ttacttcttt ttcagtgagt
    13981 cgcccttgtg aagagacaga aacagagaga gcctacttta attatttttt ctattgtttt
    14041 tttccaaatc aaatctcttt tcgacaaaaa caggagattg gttttttatt ttccacaagc
    14101 aaaaacctta tttgtcgaca agtcggtcaa ttgatgactt acttaactca acagtttcct
    14161 ctcaaccatt tagaaaataa aataccaatt tatttttatt ttcttgtgtt ggcagttgtt
    14221 tttttcgaac tgttgggtga atccagcagt agtttttcta cactttgctt tccagaagcc
    14281 acgtccaatc attctagttc ttttatacag gaaaagaaat taagagaaaa aatcgataca
    14341 attttttcaa aaaatgggga aagaaaccaa atcagtcaat accttagtca attgatccaa
    14401 cacttactac aaacagaaac gaaagagcag ttactcatcc atttgcagat aaccaaacag
    14461 tttacaggaa attatcatct tcaaagccat ttgcagcagt tatttcgcaa agatgctgtt
    14521 aaaattaccg catattcaga acatgctgat ttgatcatta cagatcagca tgagaaaatt
    14581 tcagatgaaa cggagacttt ctatctggat acaacgcaca atacagtgtt atttggcaag
    14641 ttaataaaag cggttcatga actgtatatg aaaaaaggtt atgagaacaa aacaaagagg
    14701 atgtgacaaa attcttgtca catcctctta ttccaaataa atggtattca atcagctaac
    14761 tctcggtatt agctcagatc aaagcgctga tttcacaact tctttatttt aatctcttcg
    14821 gttgccgccg aacaataaga tcaagcgcaa cagctgcagg aatgtcgaaa gcgctgctgc
    14881 aacataagtc agtgctgctg caaataatac gtgtcttgcc atcggtactt cttcttccgt
    14941 cagtagtccg ccttcactca aaatttggat tgctcgccga gacgcgttaa attcgactgg
    15001 taatgtcacc aattggaaaa gtaatgctaa agaaaaagcg aaaatcccga tattgattaa
    15061 cgtagagttc cagctaagca atacacctac cataatcaag gggaacgaaa tcatcgaacc
    15121 aaagttagct gctggaacaa gtgctgcacg aatcttcaat gggacataac ccgaagcatc
    15181 ttgtaccgca tgtccgcatt catgagctgc tacacctatc gcagcaactg aagtagactg
    15241 tgcagttgct tgagacaaac tcaacatctt attacctgaa ttgtagttat ctgtgagatc
    15301 tccggcaatt tgttgaacac cgacattatt tatctgttga ctttgtaata tatattgtgc
    15361 tgcttgtgta ccagtcacat tgtttttgct tctcacttga tcgtattttc ggaaagtact
    15421 attgacgtac gctgacgcaa ttccggaaat aactaatcca agaatgacca aaagaaatgt
    15481 cggatctaaa aaaccataca ttccataacc atacattttc gtttcactcc ttttcgttta
    15541 ctttatttta tcattagtag taggaaaaga atgtgaaaag accttgaata ttctttaatt
    15601 ctttttcaca aattccgatt tcagtttcat cggtccaaat ccttctacct tgcaatcgat
    15661 attatgatcg ccttctacta aacggatgtt cttgactttt gttccttgtt taatggcacc
    15721 tgacgcacct tttactttca agtctttaat cactgtcacg ctatcgccct ctaacagacg
    15781 gtttccattt gcatctaata ccactaatcc gtcttctatg acagtttctt gttcttcttt
    15841 gttccattcg ttcccgcatt ctgggcaaat caacaagcct cgatcttcat atgtgtactc
    15901 tgagccacat tctgggcaat ttggtaatgt catcttcttt ctcctttaaa atctttagtg
    15961 agcactattg taacggaaaa agaagatctt gaaaagatac atttgtgatt tttactacaa
    16021 aaggcacgtt ttcgaacgaa gtatcattct gtttttctgc tcttatacga ttggcatata
    16081 tcttggatct ctttatagat ttcctctact tctgctaaat cttttgcatt cgcaccactt
    16141 gctaatggat ggcctcctcc atgatggcgt ttagccaatt cattgatgat cggcccctta
    16201 gaacgtaaac gtacgcggta ataccctgaa ggctgctgaa caaaaatccc ccaagccagc
    16261 acttcgtcaa tcactccagg aagtgaaacg atcgaagctg tctctgaatc atcgattcca
    16321 tatttatcaa gaatttcttg cggaaggatt attcttcctg caccattttc atccacctgg
    16381 atattttgat aaagataacc ggaaagttta gcgactttca tcggcatttg ttcaatctct
    16441 ctgttcaaag cacttgcatc aaatggataa tttctcaata tcgaagcaat ctctaatgta
    16501 cgggacgtcg tggagggata caaaaagcgc cctgtatctc cgacgattcc tgcataaagt
    16561 aaccgtgcag ccttaacgtt catctttaaa gattcaggaa acatcaaagc aaattctgca
    16621 atcatctcac tacagctact tgcttttgta tttacccaca caagatctcc ataagggtca
    16681 tcattgggat gatggtcgat tttgatcagt ttttctgcca actgatatct ttgatcactg
    16741 attctgggtg aattagctgt atcagtcacg atgactagcg ctccttggta gaagacatct
    16801 tcaacttctt gcatttctgc taaaaagcga agcccttcaa tcgtttcacc tacttgacgt
    16861 atttcttttt ctgggaaact ttcccgtaat agttcggcta atcctacttg tgatcctaat
    16921 gcatcaggat cagggcgcaa atgcctgtgg ataatgattt tatcgtattt ttttattgta
    16981 tctactattt cttgctgtac tgtcatttca ctcctgcttt ctaagaacgt tccattactt
    17041 gacaaacaac gattgctttg gaaacgatgg tgttttcaat aaacacttcg atatccagtt
    17101 tagcggaacg tctgccgatt tccaatacac gtggacgaat gtctaattcg ctttccaatt
    17161 ggatcagccg caaataatgt aggttcactt gttcaatcaa gatatttcgt ttttggttca
    17221 tcaccattgt tttttgtgcg acatcagaaa tgatttcgct aagtacgcca aaagaaatgg
    17281 ttccaacgcc attgaccatt tgtggtgcta ctacgaattt gaacttaggg ttttccaaac
    17341 gatttccttc acggtcagta tcaatcgtat ggatatttcc agatatctga tccgaaatcg
    17401 tatctgcaat ctgcggttgt cgctggacaa gctgcatcgc tttcattaca tcttgccggg
    17461 taatcaagcc ttccaatgtc aagtcatcgg aaacgaccgg catgacttct agcccatccc
    17521 agatcatttg atggctaaca gaggcaatac tcattgtttt ctttacactg attggttctt
    17581 tcgtcatcac ccgatcgatg atctggtttg gcgatttccc taaaacatct tttgccgtaa
    17641 caatccccat caaacgatga tggcggttga cgactggaaa acgcgaatgc tgcgtttctt
    17701 ctgacaaacg ctgataatca gaaatcgtat ctgtctgctg caaataatga gtcttttcag
    17761 ctggcatata gatatcactg acaagcatga tatctttttt gatcaattgg tcgcttaacg
    17821 ctcggttgat catggttgcg actgtaaatg tatcataaga ggtgcgtaag atcggcattt
    17881 caagatcatc agctagcttt gcaatctcag cagtcgtatt gaatcctcct gtgatcaata
    17941 ctgcggcgcc atcttccaat gctaattttt ggacttccgc ccggttgccg acgatcatta
    18001 gtgatcctgg cgtaatatag cgttccatgg catgtttagt catcgcgccg atgacgaatt
    18061 tattcaagac cttgtctaat cctgccgccc cgcctaaaac gtccccttca atgatcctga
    18121 cgacctcgcc aaatgtcaaa cgttcaatat gtttttttaa tttgcgttcg atacggatgg
    18181 tccctactcg ttgaattgtt gaaactagtc cgacattttc tgcatctttg attgcacggt
    18241 acgctgttcc ttcactgaca ttcaattctt ttgcgatgct tcttacagaa attcgattgc
    18301 caacaggtaa actttcaata tattctaaaa tcaaatcatg ttttgtcgcc attttctgcc
    18361 tacacttcca gcgtttccga gacgctcatt atttttcctt cactatcttc cagtaactct
    18421 acaaaagatt cgggatcttg ttcaatgaca gggaaagtat tgtaatggat tggaactact
    18481 ttcttggcac gaattgtttg cgcagccttt gctgcatctt ctggccccat cgtatagtta
    18541 tcgccaatcg gcaagaaagc gacatcaata tcgaattctt ctgcaagcaa tcctagatca
    18601 ctgaaataag cagtatcccc tgcatgataa atcgtttttc cttctgcttg aataataatt
    18661 ccgctaggct cgcccatata ctgaacgata ccgtctactt catagcttga actatgctgt
    18721 gcatgtacga attttaccac gccgaatgga aacgcatgtt ttccaccgat attcataccg
    18781 aatgaatcta ctcctctgct gttcgcataa tcagcaatct caacaatact gataattgtg
    18841 gcttgatttt cttttgcaat aggaatcata tctcctatgt ggtcactatg accatgagta
    18901 atcagcaacc aatctgtctt tacttcttct gcagttaagt ctgtcaatgg atttcctgta
    18961 ataaacgggt caatcatcac gcgttggcca ttttccattt caattgttaa acaggaatgt
    19021 ccatgatacg taattttcat attttacacc tcgcgttttc tctgtatctt ttttattaaa
    19081 aacgatttca tcacttgcac atcaatgaaa aaatatagct gctaaatata ttttcattgg
    19141 attgatagta cagtatgtac aaagcaattg taacagataa tacaggatgc accaagtacc
    19201 aagcagatat aatctcaagt ttgaggtctc tgctctgctt agcttctctt ctcgtccctt
    19261 aactaattaa atcagcgtaa ataggatgga cgatcttttc taaatcggct acttttatcc
    19321 gaaggcttct cccgatttca ccgcttgaca caattacttc ttctttttct tttaaagaac
    19381 tgtctgctaa aaaacaataa tcaggatgtg cgagttttat tccaataggg gtgtttgctc
    19441 cgtggggata tcctgtatgc attaatacaa aatccattcc aggaaaacca actttacgat
    19501 ctttcgtcac ttgtctcgtt tttttgtaat ctaagtgatc gttcaaagga atcaatgcga
    19561 tgatcacccc agttttgttt cctttcacta cgagagtttt acatatcaaa gctggatcaa
    19621 tccctctttt ttgtagttct tctgtgaaag attcttctac cacatgacta aaatcaagtg
    19681 gttgatagct gatcttttgt tcttctaaat aacgttcgac ttttgtttga ctcatcattg
    19741 attcactccc tttattctat cgtttattat aaagcgaggg atgctgtatt caaaaattat
    19801 ttgtttttcg caaaaaaaga gcaagacgag cactctatag agaggttcat cttactcttt
    19861 ttgtttattt tttatttcga cgttgagtag cttccataat gactggcaag atcactgggc
    19921 ggcgttttgt ttgttcaaat aagtaacggc ctaattgatc tcggatgtct tgctttaatt
    19981 tgctccactc aaaatcattg ctttctaaat gtttctcaac gattgtttca atcatattgc
    20041 tgctttcttt catcagatca cggctagctt ttacgtaaac gaatccccgt gaagtaattt
    20101 gaggttttga aatgattttc ttttctcgcc gactgatagt gacaaccgct acgaaaatcc
    20161 cgtcttctga caagattttt cgatcacgta aaacaatgtt tccgatatca cctatgccta
    20221 atccatcaat cattacattt tctgcacttg tagttcctgc aacactcata cgcttgttct
    20281 tatattccag cacgtctccg cgtccagtaa tatagatatt tttgtatggc atccctactg
    20341 catgagccaa atctgcatga gcagctaatt cacgatactc tccttgaact ggcacaaaat
    20401 atgttggttt catcaaattg atcattaatt gcaagtcatt aggattggca tggccagaaa
    20461 cgcgcatatt ctcagagatc aacttcactg ttccaccagc tcgataaatg atatcttccg
    20521 ttttcgccac gatggtttcc atcgcgatgc ttggcgtagt agtgatataa accaaatctc
    20581 cttcttcaat cttgacatta cggtgtgtac cgtttgccat tttttgcaga gacttgatgg
    20641 gttcacccat tcggccagtt tctaaaatga tcagttcttc tggatcatag tttttcatgt
    20701 ctttcaacgt aacaagcaga tcttcacttg gtaattgaag tttttctaaa cgcatcgctg
    20761 tgcgaataat tcgttcgaaa tcttgaccag tcaagacaac ttttcgttgt gctttttctg
    20821 ctgcatccaa tacttgttgc actcgttgca aattacttgc tacacaagcg acgatgatac
    20881 gcccttccca atatttgatc gtatcaaata cttcatctgc tatttgggct tcagaagcta
    20941 caggctgagg attttctgca tttgccgatt cacttagtaa ggctaagact ccttctttgc
    21001 cgatttccgc caatcgtgca taatctgttt gatacattgg gatagccgtt tggtcaaatt
    21061 taaaatctcc cgtataaacg atactacctt cttttgtttt cagattgatc cccactgaat
    21121 ctggtatcgt atgagtggta cggaaaaagc tcactactgt ttcaccaaag tctatttctg
    21181 tatgctcatc taccacatgg aaatccttaa atcctttggc tgcttcatta cgactgacat
    21241 tcaattttgc taactcgatc gtcaactctg tcccgaatac tggtacagaa atttttgaca
    21301 acaagtaagg aagtgccccg atcgcatctg catgtccatg tgttaaaaag acaccagcta
    21361 cacgatcaat gttttcttct aaatacgtaa aatcagggat tacgacgtcg atccccaaca
    21421 actcattttc aggatatttt agcccacaat ctaaaataaa aatatcctcg cccacttctg
    21481 cgacatacat gttttttcca ttttcacgaa cgccgcctaa tgggataatt ttaatggtac
    21541 tcacaaactt cacctcttct tatgacatcc aagtttaaag atgtcgattt tcttctttat
    21601 ctaaatatat gagccattcc aatgaagcat atgcaaaatc actatttctc aacttatgga
    21661 gaatcagcag gaaaattacc agcacatccg cgttctgaca gttggatggg cattttattt
    21721 tggatatact tcattaacaa aatggatctt ttgcgaaacg ctatagccag aatacttata
    21781 taagtattca gctgttcccc attattatac aacaaataaa ctaaatcgct agtatcagca
    21841 attgttagaa caactatgca cgtaaaaatc cctctgtagc atctaggatt tcttttgcta
    21901 ttcctctttc atttcttctt cgtcggtttg aaacatactt ttttcatttt accacatttt
    21961 ttgcaataac tatagtgact ttttatatat acagaacctc atgttgatgg tgtgcaaaca
    22021 gcataagatt taagctagct ttaagatagg ttgtctatta tcaaatgcat ctactaggag
    22081 ggatgcaaaa tatgaatttt atgaaacgtg catggaaaag tacaaaagta aaatggggac
    22141 gttcattgtt attgtttgcc gtgttcacag ccattcttat ttttgtgcta gctggcctca
    22201 cgattcgaag cgctgcagaa gaagcagcga atcaagcaca aaaagaagtt ggagcaacag
    22261 tgactttaag tgccaatcga gaagcttcat ttaaaaaaca ggaacaaact tcttcaagcg
    22321 gttctaccac tgaagaacgt ccagatccag gcagtttttc tcttacacca gtttccttaa
    22381 cggacgcgga aaaaatagct gaattagata atgtaaagag ttattccttt gaaagttccg
    22441 cctcagctat ggcaaaagat ggaataactg ccatcactag ttctgattca agtgaagaca
    22501 gttcagaaac tactgatgca ggcggtgaac ctgctggagg aatgggcggg aatccgcaaa
    22561 tgactcaagc agactttcaa atcagtggtg tgtcagcaac tgcacaaaat agtaattttt
    22621 ctgatggaac agcaaaaatc acggatggtg aaggaataga tgacagcgac aaaggcacaa
    22681 acaatgtagt cattgattct actctagcag aaacaaatga cctggcagtc ggagatactt
    22741 tcacaatcac gagtactgaa gatgaagata ccacttatga aatgacgatc aaaggaattt
    22801 atgaatccag cgaaacaagc ggcagtatgg gtatgaaatt caacttcatg aatccgtcga
    22861 atacacttta cacttcttac acttttgcaa atgaactaaa tgggacatct gacgataaca
    22921 cgatagattc tgctatttac actctatctg atccagataa aatggatgag tttctcaaag
    22981 aagctgagaa gctgatcgac acagatacat ttagcttaca atcaaatgat tccatgtatc
    23041 agtcaatgtt ggaaccttta aacaacgtgg caagtttttc taaaaatgtt gttttactag
    23101 tggctgtagc cggtattatc atacttactc tgatcattat gattaccatt cgggagcgtc
    23161 ggcatgagtt aggcgtcttg ctatctttag gagaatccag aagtaaaatc attctccaat
    23221 tgtttaccga agtggctatt tgtatgattc ttgcattagg agttgcttcg cttagcggaa
    23281 acgtcgtcgc gaatgccgtg ggacagcagc tacttgacca acagacagaa accacgacac
    23341 aaaaccagca agctcctggc ggtggacaaa tgccaggtaa cagacaagaa caaggcggtc
    23401 aacgcgatgg tcaacaagga accacgaata atccatttgc tgtttctgat caagtcagcg
    23461 aattggaaat caatgtcaaa cctgcacaat tgggactatt agccggagta gcatttggaa
    23521 tcagtctgtt ttctgtcttt ttagcttcta tagggatatt aagattaaac ccaagaaaaa
    23581 tcctattaaa ctaaaggagg aatttgatgt tacggacaga acaattggga ttttggtatc
    23641 aagatccgca agatgcgctt tataaagatg tagaactgaa tttcgaagct ggaaaaatgt
    23701 acgctatttt aggagcaagt ggttctggaa aaacgacttt tctttcgctt atttctggac
    23761 tagatgcacc aaaagaagga aaggtatact atcaagatcg ttcactgaac aaaatcgggt
    23821 taagaagtta tcgtaaaaat gatgtctcga ttattttcca agcttacaac ttgcttcctt
    23881 atttatcggc tctagacaac gtcatagcag caatggaaat cactaagacc aagcaagaga
    23941 attatcgaca agttgcttta gatcgactgg ctcgtgtagg aattgatgaa atattagcaa
    24001 aaaaacaggt gaccaaactt tcgggaggtc agcagcagcg agtcgctatc gttcgtgcta
    24061 tctgctgtga acatcaacta atcgtagcgg atgagcctac tggaaatcta gatgaaacaa
    24121 cttcacaaga tatcgtcaaa cttttccaag aaatcgccca tgaacaaaat cgctgtatta
    24181 tcatcgtgac tcatgagatt gaagtagcaa aaagctgtga tgaagtcttt gaactaaaaa
    24241 ataaaaaatt tcaaaaaatc gaagtttaaa aaacaggata atgatcaaat aaaaaatccg
    24301 aaccatatct gtctcgcaga tatggttcgg attttttatt tgcttgattc aattagtaat
    24361 aagtggtttt tatttttttt cgtcttttcg agaaaacttg tctttgactt cgtcgcctaa
    24421 atttcgagct ttttctttga tgtcagcacc tagtgattgt gctttccctt ctgtttcttt
    24481 gctcttgtcg tctgttgctt tgccgtatgc ttcttttcct tcaccgacta ctttatcttt
    24541 catatcttta gaacgtcctt ttaaatctgc cattgtgctt cctcctctta gtttgtttat
    24601 tgatctacct tcagggtaac atcaacaaca gatacagaca aacagaacgc tcgttttcta
    24661 aaaaagatag ttagagctgt tgattaaaaa cttttttcga aagtccccca tactttgact
    24721 tctttttctt ggaccattat ttctccttta gcgataactg tatcaatatc aagcgtttct
    24781 ttatccaaga tacacagatc tgcatcagca ccaatttcga tttttccttt tttatccaat
    24841 ttcaatatac gtgctggatt actggttata gctcgtaagg cgatttccaa agggatactt
    24901 tctttttgca cagcttcttt gatccctact agcaatgcct tggcacttcc tactcctaac
    24961 cctaggaaat gattgttttc atcaaaataa ggcaagcttc cttgtccatc tgaggtcatc
    25021 gtgaaattat ctaaagaaac atcttcctcg atcaatcgtt tcagtgcttt gctgaagcga
    25081 acttcaccat ctgtcttctc ccaaaaatca ggatcttcgc tagcagtgaa gtcaatcgtg
    25141 ccaccacgtt tggcaaatgc cacgcaagct tcaaataatt ctggtgtgcg atttgcatga
    25201 gtaggcaaaa attgtgtgat cggaatttct gtttcttcta cgattcgtgt caatagctct
    25261 agctttcttt ttcctccgcc taagtggaca ttgatgatcc cagcttttcc ggataacatg
    25321 cctcctacac gagcatctgc tactgcacga gcgaactctt caaaacttgg ctgagaagaa
    25381 cggtgatcgg atactgcgat ttctccgatt ccgataattt tatcaattgt caaaaagtct
    25441 ttgatgatag aatctgttac tgtttttacc ggcaatcggt acgaaccttc gtatacataa
    25501 gtggagattc cttctgcttc cagacctttc gctttgctga tcaacgcagt catatctcta
    25561 ccttctccgt ctgttcccaa acaaccgaca actgtcgtta caccagctgt agtcaattgg
    25621 ctcaatgtga cttctggcgt tcgattttga taaccgcctt ctcctcctcc acctaaaata
    25681 tggaaatgac agtcaatgaa acccggggtt agtacttttc cctcacctga aagttcttct
    25741 acttccactc cttcgtagcc gccttctagc tgttcttcta cagccaaaat cttcccaccg
    25801 gcaatcagta catccatttt tcctaagtaa tctggtgcaa acacttcaat ttgtcgaatg
    25861 attttcatac atttttcctc tttctttaag tataactgat gataggatct taaaaaataa
    25921 tccaaacgat aggatcttta ctcctttgat tttaccgtaa aatgacggtt cttggagtcc
    25981 ttatctactg tttggattac ttttttattt acaggtctcc agtactactg cagacctatt
    26041 gcaatggcaa tcatgatgaa aatagttcct aaaacaaaca ggaatccttg catcttgatt
    26101 tggaatcttg cccattttgc ccattcgatc cgtgcaacac ctagcacacc aatcaagctg
    26161 gctgatacgg gtgtaaaagc gtccataaaa cctgaaccaa gctgataagc aagaactgct
    26221 acttgtctgg atacacctac taaatctgcc agtggagcca tgattggcat agtcaaagct
    26281 gcttgtcctg aatttgatgt aacaaccaag ttgaacaaac tttggaagat gtacatcgcc
    26341 caagcaccaa tgacagctgg aacaccggtc aacgccgtcc cgatcccatg caaaatcgta
    26401 ttcaaagctg aaggaacaga tgcatcagat cctcccaaga caagaagaat ccctttggcc
    26461 atacctacta cgattgctgt accagctaaa tcagctgcac cagattggaa agaagaagcg
    26521 atgtcattga ctttcattcc atctaatttg aaaagaacag caatgattcc agcaactaat
    26581 cccatcacaa agaattgaga agcgatttct ggaatgtaat agcctttttg agtcacgccc
    26641 caaacgatcc agacaaggac aactaacatc tctaataaga tcaatttatg cccaagcatg
    26701 aattttttat tttcatcaga tgtctttttg atatgagaac ggaaataatc atctgatttg
    26761 taagtcaacg aactttctgg ttttttacgg attttttctg catatatcat catataacca
    26821 gcggctaatg cagtaacaac tacccacata atcaatcgga atgtcgcacc agacaacacg
    26881 gggattccag caatcccttg agccaccgct acgctaaacg ggctcatcca agaggtcgca
    26941 tttccgactt gagatgcgac ataagtcacg gttactgcta cgatcgagtc atatcctaac
    27001 gcaatgacaa atggaaccat caccattgag aatggaatta cctcttctgc catcccgaat
    27061 gtagcgccac cgaatgaaaa agcaaagaat aatagcggta aagctaaacg ctccagtccc
    27121 ttagttttac tgataaacgc atagatacct gcgtcgatcg ctccggtacg cataataata
    27181 ccaaaagcac ctccaacaac aaggatcaat gcagcgatcc ctacagcaga tccatactta
    27241 tctccagata ctagtccttc aaaaacaaaa tttaagaaac caaagccgcc aaaatcatct
    27301 gttccccata ttttggctgt tttatgcaat tttttagaag tatcatagat attttcgccg
    27361 tactgatcgt aaagcacatc atctgtcaag gagatttcat ctagtttttc ctgcgtaaga
    27421 tttttttctc cgtcagcaat gactttttcc aatccttttt ccggaacatc cagtttttca
    27481 cgttctgctg gatgatcttg cagttcttct aattgatcaa acacatacga cttatccagc
    27541 tcgtaagcat aacggaagga atcttgacgt aaaacagtac gagtacttgt ttcgccattt
    27601 gcatctttgt attcaatatc ttgcgtgctg aactttcctg ctggaacgac aaaagtcagt
    27661 atccatgcaa agatgactac accaaaaata atgacatacg tatggggtgt cgataattta
    27721 gtgaagtcgc gtttcggttt tcctgaagaa tttgttttct tcaaatttat ttcttccttt
    27781 cttttttcag taattttgat gaataaaaaa tggataatca aatgaattat acagtaaaaa
    27841 tgacatttcc acatgaataa tttattagaa aatcactttt ttctattttg ttttttttct
    27901 cctatgtatg attatttttt tctctttcca tttatattaa gtattttatt tctctgtttt
    27961 tccttaaaat tcttttttta tttttagatt agagaaaatc tcgtcctgtt tttttcattt
    28021 tacaatcatt gaaaaattga atttcattgc aaaaaaaata ataaacactt ataaatatcc
    28081 attatctatc cttcaatttt tgtgtatttt atttctatta gaaaaaggta tcctgttgga
    28141 caattttgtt atatcaggta aacttcattg caataatgat aacaaatgta ctataattac
    28201 tttgtaaaga gttttgggga agactctttc atcaacgtgt attaagagac aagaaagaat
    28261 ccatatggat tctttcttgt ctctttttcc actacttttt atttttctga cactacatat
    28321 tcttataact catttctcat aactgtgaaa caacttataa aaataacaaa ctttaaacaa
    28381 aacaagctta aaatcaaaga tgatccatct taaaataact aaaacaaaaa aagtagtcgt
    28441 tgttaatcct cattaataat cgttttcttt ttttcaaacg ctccattttt atgtggaaca
    28501 ttattttttt aaggaacttt gtcaacatgt ggataactat tttccacttg tgtcctggac
    28561 tagctgtttt gctgtaaaat acaaaacttg ctgcagcaaa aagatcgttg caagagaggc
    28621 tgttccgcag atcgctggat ctagatttgg caaagtcaag actgcatcat gtaaattggc
    28681 gtggttgtcc aaaaccaaat cagcaaattc aaataatcgc aaaccactgc tatgttgcga
    28741 tttgatactt cgtgacaaat caaatccagt aacaatgatt aatggatgac cattttcttt
    28801 gatccactga gctagttcga tgattgccgg gtttcttcct tcattcgaaa gaagaagaaa
    28861 aatgtcttct gatttgacag aaagctgatc aataattgcc tgtcctgcac cttctagcgt
    28921 ttcatagaca cctccggctg gattttcaat caatatactt ggtacaagat ccggggtttg
    28981 atcccaaaat tcaaatgcta caccacttag tgtgcggcta gcatatatct gcaatctacc
    29041 accttgatta atttgtttcg cgatccaagt gccagcttga agcatcagcg tctcttctat
    29101 ccttaatttc tcttccaatt ggtgataata gtcaaaataa cataaactca tttatctctc
    29161 ccgcctagct atacttgaca tgaatagaaa cagctgccta atctaaggaa gtacataaaa
    29221 aaacagtagt tagacagtaa cacatgtggt ctttgctgtt tcaaacacaa aaaaggcatt
    29281 gaacgaatac gcccaatacc ttgacatagc aaataaaaca acgtgcagac catggaaaat
    29341 atctacatag gggtagaatt ttcaccctag attaggtaca ataaattagg tcgatgcact
    29401 gcattgacta tggcaaaatg atcggtcagg gtgtatgtgt gtgactggtc attccctgat
    29461 tcttagcgcc aactaagggt cagggagcct ttttttattc agctgtttct atctgaattt
    29521 attgtaagta atctcttatc caagtgcaag caagaaaata caaaaaaaca ttggtatgat
    29581 ttatatatat ataaataaca taaaaaaagg aatggcttat cccgatacaa caagcattcc
    29641 tttaaaaaag attcttttat ataagtgaaa aaagcttttt tccaccaatt aaataaatct
    29701 ctcatctcaa tagtttatcc attattttat ctttttttgc gtatacctac taaatattac
    29761 cgtcttcttc tcgttcttct actttgttcg agagaatctg tactagaaaa agtagttgta
    29821 tgtctacctt ttctgcctat ccgagacttt cttttcatat atgggatata aatgattaga
    29881 tacagtacag caaaaaataa agcaaatacg caagcttccc aactacctaa cgccaattca
    29941 accatcaagg tagcaacccc aacggatgct gcataccaga taaaaatcag aaacgtttct
    30001 ttttttctga ccatgcgaaa catgataaat agactaataa gcaatagtgg caacacaaat
    30061 atccaattgc ttccttccat cagccacttg agtatatcaa gcagcgactg tgcaacagcg
    30121 actaattttc ccatagtgaa cacacacctt tttttataat taaaaaattc gcctttttat
    30181 tctactatga atcttctggc ttggctttca tttctcttat gtaatcattt tcttttatac
    30241 aacttaaaaa aaaattaaac cattagcata atattttctg aatctattca cgaaagtctt
    30301 tttctatctt tcgttttcca cgactcaact gatctagagt caaaaaacta aaacgacagt
    30361 tgcgcaaatg acgcacaagc tgccgcttta ataacaaata gcctttcatt ctcagcaggc
    30421 cacttatttc cagttaactt tctgttctta gctttttact caactggata atatatgcac
    30481 ttaatgaagt cccaatttcc gaatgttgaa gtccatattc aatatttgtc ttcatatatc
    30541 ctaacttatc gcctacgtcg tatctttttc ctttaaactc tctcgcatag accgcctctg
    30601 tctggttaag agtctgaagt gcatccgtta gctgtatctc gtttcctgct cctggttctt
    30661 gagtttctaa tatctcaaat attttaggag tcagtagata acgtccgata atggctaaat
    30721 tacttggtgc ttttcccatt tcaggttttt ctacaaaccc ttttactctg caacgaccct
    30781 tttcgctatc tgttttagga tcaataattc cgtatttaga tgtttcattt tctggtacac
    30841 gcatgacggc aacagcggaa gcttgtgttt cttcataatc catcatcaat tgttgagtca
    30901 atgggatatc atctttcatc aaatcatccc ccagcatgac gacaaacggt tcatttccta
    30961 taaatgcttt tgcttgaagc acggcatccc ccagtcctct tggatgagat tgacggatga
    31021 agtgaagatt gacttgagtc gtttcttcaa ctaaagcgag taattctgtt ttttcctttt
    31081 cccgcaaatt gttttccaat tcgatatttg catcaaagtg atcttcaatg ggtctttttt
    31141 cttttcccgt tacgatcaag atgtcttcga ttcccgaatc caatgcttct tccacaataa
    31201 actggatcgt tggtttatcc acgattggaa gcatttcttt tgccatggct tttgttgccg
    31261 gcaaaaaacg tgttcctagc ccagcggcag gaatgactgc ttttttgacc ttcactt
//
LOCUS       DADGHT010000026        29196 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.026, whole genome shotgun sequence.
ACCESSION   DADGHT010000026 DADGHT010000000
VERSION     DADGHT010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29196
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.026"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            16..354
                     /locus_tag="JX887_001033"
     CDS             16..354
                     /locus_tag="JX887_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HAX1257039.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            341..520
                     /locus_tag="JX887_001034"
     CDS             341..520
                     /locus_tag="JX887_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257040.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(563..1033)
                     /locus_tag="JX887_001035"
     CDS             complement(563..1033)
                     /locus_tag="JX887_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257041.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            1120..1827
                     /locus_tag="JX887_001036"
     CDS             1120..1827
                     /locus_tag="JX887_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAX1257042.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFDKKHRHVLTAIDELKEGVAEN
                     WADLFWEDTYVHPQNKQSYRIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKE
                     LKDQLPSIPATKREMALLALAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMV
                     RNKIRVICNQQHLNSKAKAELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMP
                     STATMTIIKQMELLEDE"
     gene            2006..2347
                     /locus_tag="JX887_001037"
     CDS             2006..2347
                     /locus_tag="JX887_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257043.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            2340..3086
                     /locus_tag="JX887_001038"
     CDS             2340..3086
                     /locus_tag="JX887_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAX1257044.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFDKKTGYMVFTSITVNGVKRDMWLPVMDGANKA
                     MKDEPYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLG
                     LYIFAGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITAD
                     DSKWTKRDLGILKRGVNWIEDQYREETKEK"
     gene            3092..3778
                     /locus_tag="JX887_001039"
     CDS             3092..3778
                     /locus_tag="JX887_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257045.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            3785..4618
                     /locus_tag="JX887_001040"
     CDS             3785..4618
                     /locus_tag="JX887_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer"
                     /protein_id="HAX1257046.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            4635..5486
                     /locus_tag="JX887_001041"
     CDS             4635..5486
                     /locus_tag="JX887_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1257047.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            5483..5842
                     /locus_tag="JX887_001042"
     CDS             5483..5842
                     /locus_tag="JX887_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAX1257048.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            5857..6018
                     /locus_tag="JX887_001043"
     CDS             5857..6018
                     /locus_tag="JX887_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAX1257049.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            6015..6320
                     /locus_tag="JX887_001044"
     CDS             6015..6320
                     /locus_tag="JX887_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257050.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKTR
                     RRMPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRAKNMDIDSKGRQFRYVEEK"
     gene            6320..6637
                     /locus_tag="JX887_001045"
     CDS             6320..6637
                     /locus_tag="JX887_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAX1257051.1"
                     /translation="MNLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     GSK"
     gene            6634..7020
                     /locus_tag="JX887_001046"
     CDS             6634..7020
                     /locus_tag="JX887_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257052.1"
                     /translation="MIPRFRSWYTPFKGKTIGQEMKYGQAGRLITHAEMAPDKYVLMQ
                     STGLKDKNGVEIFEGDVVLVNVSNGFDHLVNEKTVVQESEFHSGLVCKSLISGMEYRI
                     FSHQKMGYEYEVTGNIHENSELLEVE"
     gene            7017..7352
                     /locus_tag="JX887_001047"
     CDS             7017..7352
                     /locus_tag="JX887_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257053.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDIHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEQ"
     gene            7498..8067
                     /locus_tag="JX887_001048"
     CDS             7498..8067
                     /locus_tag="JX887_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAX1257054.1"
                     /translation="MNKQEAIKKLESIKVIGNDALAACYNESINAGITLMKKIDEPKK
                     LVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLYSVIIAGEYLVKEISCSNEVKLVSTAYLPQYLAH
                     HYQLTEKQIKAIDERYWPFAVPVEEVAEG"
     gene            8234..8539
                     /locus_tag="JX887_001049"
     CDS             8234..8539
                     /locus_tag="JX887_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257055.1"
                     /translation="MNVQVYLKRDLARFPRSWDTNSHPSEAEEEGYLMSANMIEITRD
                     DADEFDKKRSWYSVPNPMYTAVIEDYHISDRFILIDLERPKKRIKQYRRCGFSTKKW"
     gene            8563..8760
                     /locus_tag="JX887_001050"
     CDS             8563..8760
                     /locus_tag="JX887_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HAX1257056.1"
                     /translation="MNNRHRRVAKLRNQELNVAKVKFEREYGVSAEETYKVASQCVAD
                     ASDAIRKFGISILDIKWEDTE"
     gene            8757..8963
                     /locus_tag="JX887_001051"
     CDS             8757..8963
                     /locus_tag="JX887_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257057.1"
                     /translation="MKIYVVKFGNQFYRSDERSIGANTLSIVDILQSARWFDNLEEAN
                     QVSRRLGGLTQVYELVTVDHEGVE"
     gene            8963..9259
                     /locus_tag="JX887_001052"
     CDS             8963..9259
                     /locus_tag="JX887_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257058.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTREKPKFKVGDMVRCEA
                     EGFIYPFRGYVEKVLSNSAIIRIENTMECDKWLAKSKENLAVARLVDMEVIESK"
     gene            9335..9748
                     /locus_tag="JX887_001053"
     CDS             9335..9748
                     /locus_tag="JX887_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAX1257059.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            10625..10969
                     /locus_tag="JX887_001054"
     CDS             10625..10969
                     /locus_tag="JX887_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAX1257060.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            10974..11255
                     /locus_tag="JX887_001055"
     CDS             10974..11255
                     /locus_tag="JX887_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257061.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVDIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            11358..11672
                     /locus_tag="JX887_001056"
     CDS             11358..11672
                     /locus_tag="JX887_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HAX1257062.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            11650..13344
                     /locus_tag="JX887_001057"
     CDS             11650..13344
                     /locus_tag="JX887_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAX1257063.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            13364..14542
                     /locus_tag="JX887_001058"
     CDS             13364..14542
                     /locus_tag="JX887_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAX1257064.1"
                     /translation="MGIFQKAVGYFTKKATVTLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            14505..15191
                     /locus_tag="JX887_001059"
     CDS             14505..15191
                     /locus_tag="JX887_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAX1257065.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            15191..16351
                     /locus_tag="JX887_001060"
     CDS             15191..16351
                     /locus_tag="JX887_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAX1257066.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            16361..17236
                     /locus_tag="JX887_001061"
     CDS             16361..17236
                     /locus_tag="JX887_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257067.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIKIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            17233..17544
                     /locus_tag="JX887_001062"
     CDS             17233..17544
                     /locus_tag="JX887_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257068.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            17534..17887
                     /locus_tag="JX887_001063"
     CDS             17534..17887
                     /locus_tag="JX887_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAX1257069.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            17877..18278
                     /locus_tag="JX887_001064"
     CDS             17877..18278
                     /locus_tag="JX887_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257070.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            18271..18675
                     /locus_tag="JX887_001065"
     CDS             18271..18675
                     /locus_tag="JX887_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257071.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            18687..19292
                     /locus_tag="JX887_001066"
     CDS             18687..19292
                     /locus_tag="JX887_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1257072.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            19312..19674
                     /locus_tag="JX887_001067"
                     /pseudo
     CDS             19312..19674
                     /locus_tag="JX887_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            19677..19859
                     /locus_tag="JX887_001068"
     CDS             19677..19859
                     /locus_tag="JX887_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257073.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            19877..23296
                     /locus_tag="JX887_001069"
     CDS             19877..23296
                     /locus_tag="JX887_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAX1257074.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITAIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQTFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKIQNDNASAWR"
     gene            23347..24084
                     /locus_tag="JX887_001070"
     CDS             23347..24084
                     /locus_tag="JX887_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1257075.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            24094..26385
                     /locus_tag="JX887_001071"
     CDS             24094..26385
                     /locus_tag="JX887_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257076.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYDTAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNKPFLSFGAPNFR
                     YSNASYITDGDGSSLSINGSAGSSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKNFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDVRLKEDTAYDSTVLDQKRF"
     gene            26409..28490
                     /locus_tag="JX887_001072"
     CDS             26409..28490
                     /locus_tag="JX887_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257077.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSITSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFLAEIKGRMDSLNKQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLHVMYSNSIDFGGYDYSGNPNLMSKLKSSDFN
                     VGYHGSLTNVNGMLHFMSDGTGDIDMFTRINTPQLASGKTYTLSAKVRFDEGTTGAID
                     KLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYISVSFSN
                     RDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWVGKTSLGKNIANKGTTFPIKSSAY
                     EIYKGNTEEELIIGQTYTITLKGTKPASQTFVAYNYWNVNFGDLKPVEGLTDVWSLTF
                     TPTKLEPGLPKDLRIFQSPKETAGACRIDWLKIEKGDTRTPNIEQYKYRGIGMRDSNN
                     PKDYVWDLEPSYVENNLATDIKVAEITGKANNYTDGKVSEINSQLTASINEVDTTAKD
                     AQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALN
                     GKRSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYG
                     SDYTFAITYTI"
     gene            28653..29099
                     /locus_tag="JX887_001073"
     CDS             28653..29099
                     /locus_tag="JX887_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257078.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            29101..>29196
                     /locus_tag="JX887_001074"
     CDS             29101..>29196
                     /locus_tag="JX887_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAX1257079.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEE"
BASE COUNT        10510 a         4350 c         6245 g         8091 t
ORIGIN      
        1 agggaggaac agctaatgca atatctagaa gcaaaaatcc caattccaga aggctatgta
       61 attatctccc aagtggatta tgaggagtta aaaaaagctg atgatactgg tagatggatg
      121 acgttgccag aagtgctaga acggattaac agaaaatatg attggtttac ttctagagtt
      181 ttaaagaacc caagatatag aaatattatc gatatcgaga aaaacaaaaa tggatttgtc
      241 tattatccag ttgaaggaag agacacatat ctatttttaa gaagtaaaac acttgaattt
      301 ttagaaacaa atttttcgga aatcttaagg aggcaagcgg atgggaaaat ttaatagagc
      361 gctagtgttc agcgcaccgc taatcatcta cgctttagga ctttggggaa gcaggcaagc
      421 gttgatagga acgattgttt acatggtttg gatttttatg gggcttgatg aagctgaagc
      481 tgagtacaga gcgaaaaagc caaccgaggg ggctgactaa aaatgaatag aaaagagaaa
      541 ctagaatgta tattactatt actcagttta attctttcac taatttctct attgggaagt
      601 ttgtattttt gatatcaaca attttgtgga tttgggttct atttagagta aatatcattt
      661 ttgtttggtg attaaggagt ttattaaaat taattttccc tacttcaaat gcaaggtaac
      721 aagatatagc acttttagga ggaatattta gcggtacagc ttcagagtat attctattat
      781 catcgactga tcctccttta gcaattaatt tcttaaatgg agtagctgac catctgcggt
      841 ttaagttagc ggatgaaagt tctaaattaa ctaacatagc tggttctgtt gaatagttag
      901 aaatgattac ttttgtataa atcatatctg cagcgaagta agaagcatta agttcaactt
      961 ctagttgagg gcgcattcct tttattttta tccctgttaa aaacgtactc aatataaaac
     1021 ttattattga catccattga aaaattgtta agtgaaaaaa attcaaaata aacaccacca
     1081 gtttttaact aaattatacc aaaaaggaga gaagaaataa tgcaagaatt agtaattttg
     1141 aaaaataaag aagctgtgac tacgagctta caagttgcag aaagcttcga taaaaagcac
     1201 agacatgttt tgacggctat tgatgaacta aaagaggggg ttgccgaaaa ttgggcagac
     1261 ctattttggg aagatactta tgttcatcct caaaataaac aatcataccg aattatttat
     1321 atgaatagag acggcttctc tctattagca atgggcttca ctggtaagaa agctttaagt
     1381 tttaaacttc aatatattga ggccttcaac aagatggaaa aagaattaaa agaccaattg
     1441 ccatcaattc cagcaactaa acgagaaatg gcattacttg ctctagctgc aaacgaagaa
     1501 acgaatgaaa gagtagacgc tatcgagtct gatttaaacg atttgaagaa caatcaactt
     1561 ctagctgaac cagattaccg aacaatttct aatatggttc gcaacaaaat tagagttatt
     1621 tgtaatcagc agcatttaaa tagcaaagca aaagcagaat tgtttaaaga cttgaatggc
     1681 ggaattaagc gaatcactgg agcagtagct agaaatcgta tcaaggcaaa acagttcgat
     1741 gatgttatcg attttattaa caattggatg ccttctacag cgacgatgac aattattaag
     1801 caaatggagt tgttagagga tgaatagagc tgaagcgcta aaaataggcg taataattgc
     1861 taatcgctgg tggagacaca ataaaccaaa catcctaagc caacaacata ttgataagca
     1921 aaaagcatgg caacaaataa aaaagtgact cagccgacca aagcaatgag tcacaaagaa
     1981 aatacatcta aggagatgtt accacatgaa aaaagaactt tccactctag atcaatattt
     2041 gactgatcct agttggggca aatcgaatat caaggaaaca agcaatcgaa aaatcagacg
     2101 taatcttttg acggatgaag aactagcatg tgatcaagac gatttgggaa attttgtgag
     2161 tatttgggat catgtctatc ttatccattt atcgaggaag tccaaaaaaa ctgaatatat
     2221 ctatgtcatc gaagatggct tgattgatgc gctagaagag tatgacagag ataacttgat
     2281 tgatatctct tattacggat caggtaagaa atacattgct gaaatggagg cagaatttga
     2341 tgagtgaaaa ggaacaacct ttgaaaaata gaagtgataa tacgcttttt aataccttat
     2401 acaaaataaa tgtgaaagat gttactgaaa aacgaaataa cctcacttat ctttcgtggg
     2461 catgggcttg ggcagaagtt agcaaagtgt gtgaggcagt agattatgaa atctatcatg
     2521 atccagaaac atatctgccg tatgtctttg ataagaaaac aggctatatg gtttttacca
     2581 gtatcacagt caacggagta aagcgtgaca tgtggttacc agtcatggat ggtgcaaaca
     2641 aggcaatgaa agatgagcca tatacctacg aagtcaatga ttatcagtgg aataacgaaa
     2701 cgaagaaaaa agagattgtt ggaaaaatcg aaaagcgagt tgaagcagca actatgtttg
     2761 atatcaacaa aacgatcatg cgctgtcttg taaaaaatct agcaatgttt gggctagggc
     2821 tatatatatt tgctggcgaa gatatgccag aagatgtctc gatgcttgaa ccagctactc
     2881 aaagaagcaa aaagctattc ttggatgctt tacaactggt tgctaacaag tacgaaaaat
     2941 caattgatga agcaattgtt gcattgactg atgcggcttc tataaccgct gatgacagta
     3001 aatggaccaa gagagacttg ggcattctaa aacgaggcgt taactggatt gaagatcagt
     3061 acagagaaga aacaaaagag aagtgatatg agtgtttaaa ccattgatcg attcatattc
     3121 agcggttctg aaaaagttca aaggaaaaga cataggtgca acgatcaatg aagaagtgaa
     3181 cattgatcga ctaaagacga tgtatgacgg atatgatggc gatcggatta ttgaagttcg
     3241 atttattgat ccacgtcgat ttactgtgca gcaacgaaac ttcatctatg cgctgatagg
     3301 cgatattttc atcgatacag gcatgccaac ggacttctgg aaggaattct tttacttccg
     3361 ttttgaaggc gtcacagggc gcaaaataag cctcaaagac gaatcgaata caactgtgag
     3421 tgatgctaat gtcttagcaa atatcatctt agatttcatc tttgaacatc atattccttt
     3481 caaagaaggc tatgagattt taccagcgaa tcaagaatat tacttctaca aatgcatcac
     3541 aaaaagagtc tgctgcatct gtggcaaaac aggagctgac atcgatcact ttgacaaagc
     3601 gctaggaaga cgaaagcgca aagaagttga tcattcagag tacacatttg cagcactctg
     3661 caggattcat cacacggaga aacacaatat aggtgtgatc aatttcaaaa ataaatatca
     3721 aatcaaaggg atcaagttaa accaggaaac aattaagaaa cttagaatag gagggtaaaa
     3781 aatattgtct gacaacaaac gctactacta tttaaaacta aaagagaatt ttttcgatag
     3841 tgacgagatg gttctcttag aaagtatgcc agatggctat atttattcta atattcttct
     3901 caaactttat ttaagaagtc taaaacacga aggtaagttg atgtttaatg acaggattcc
     3961 atttaactct acaatgctcg caactattac aagacattct gtaggagtcg tagaaaaagc
     4021 ggtacaaatt ttccgtgatt tgcagcttat tgacgtatta gataacggag caatttatat
     4081 gtctgatata caaagtttca ttggaaaatc ctcaactgaa gcagatagaa aaagagaata
     4141 cagaaagaaa atagaagagg caaaacggaa tttaataact ggaggacaag tgtcggacaa
     4201 atgtccagac aaaactacac cagagttaga gatagagata gagaaagata tagatataga
     4261 taaagaagaa aagaaaggta agtattctga cgaacactta cgccttgcta aaaaattgca
     4321 aagtaattta actgaagatt ttccaaaaga aatgaacaaa gtagatatcg aaaaatgggc
     4381 agacacaatc aggttgatgg aagaaagaga taaagcgtct atagaagcga ttgagtatgt
     4441 gatcaattgg ctacctacaa atgaattttg gtttggaaat attagaagtg ctaagaaatt
     4501 gagagaaaaa tttgagaagc tcaaattcga aatcaaagca gacaagaata atcataaaaa
     4561 gcaaagtcaa aaactacagt acagcaatcc tagtgaatat gacgacttgc caatttaaaa
     4621 aggagatgca tcacatggaa agcctagcaa atgctatgga gaaactaata agaagagtat
     4681 tagtgcaaag cgggaaatgt ccagaatgta gcgaaccttt gtatagttgg cgagctaaaa
     4741 ataaggatgg ttcagaacgt tgtaaaccaa catgcatgag ttgtggttat aaagcgttac
     4801 gtgtgaaaga ggatatacag accgaacgga tatataacga cagcttaaaa gcacgagcgt
     4861 tgagtttttt tcaaaatggt tcggtattaa cagataaaac tttgtttaaa tgcaaaatgg
     4921 agaattatca cgtagtggac caagaaacga aaattgcttt agaaagagct aaaagctttg
     4981 taaatgatgt cttactgaac catcctgcac atttcattct atcagggaaa tcaggaagcg
     5041 gaaaaagcca cttgtcaatg gcgacagctt gggaaatact tgagcgctca aattatgaca
     5101 agaaaatact ttttataagc tatcaagagt tattagagca aataaagttt tcttataaca
     5161 atgctgaact gagaaaagaa attgaaggat cgcttatagc cgatattaaa acaactgatt
     5221 tggtggtttt tgacgatatt ggagctgaat taggtagtgg ggtatcaaat agtaggcagt
     5281 ttacaaacaa cacgttaaac acgctcttag aagcaagaca gaacaaggca acgatcatca
     5341 caacaaactt atctggtcct gaactaagag aagcctacgg tgaaagaatt gtttctagga
     5401 tatttaagaa ttcagaaggt tatgcgctga aattccagca aacagcagac aagcgcataa
     5461 aaccagtgaa aggtagtatc gcatgaataa ataccgtaat aaaaaaactg ttcatcgagg
     5521 tatcaagttt gattctatcg cagaagcaga gtattacgat ctagccttgt ggcaagctga
     5581 agcgaatggc tggaaagtaa aacttcagga aagatttgag ctgatgccga aatttgaact
     5641 agacggaaag aagtatcgca agatcgagta tattcccgac ttcacatttt ataaaaacgg
     5701 caaacttgtc aaagtcgtag atgttaaagg aatgcagaca aaagacttta agatcaaggc
     5761 aaagctgttt tgtcatcaat atcaagtgcc gttgatatta gctaaaaaat atcggaatac
     5821 gttcaaggaa gagcgttttt aaagaggtgg tctatcatga caacagaaga agtgattcaa
     5881 atgcgaattc gaagcattca acgtgagatt gacgatctgg aacgaacaaa ggcagtgatg
     5941 gtcaatgaaa cggcgagaaa ggcaatcgat ttgcacatag agaacttaag aagggaaatt
     6001 cgtagattgg aggaatgagc gtggataaga aagcagcaat gaaacgaatc atcgaactga
     6061 cacattctga gaattggcaa gaagacaaag aaatagttgc agaagtccaa aagctcggta
     6121 aatcaatgtg gactgaaaaa accagacgga gaatgccgag aaaaattgca atctggcacg
     6181 gtgaccgaat tctagtaaca ggtaccgctg aacagttatc tgaaattact ggtctgagca
     6241 aaaacatcat ctgggataga gcgaagaata tggatattga ttctaaagga agacagttta
     6301 ggtatgtgga ggagaaataa tgaatctcat tacacaatac agtgatatca tcctcaagaa
     6361 aatcatgatg aagattcaga aagacaaaaa atcaaaagaa cgagcggaat tagttaagtt
     6421 ggaaatggct gaaacagggg caggagtgcg aagtagcagg cattggaagg cagcagcaaa
     6481 cattgaattt tattacaacg aaattcaaaa agggttcgat caaatgcgtg agctggatcg
     6541 gcaaacaaat tggagcaaga aacttcatca agatcgtttc aaatttgtag agaaatataa
     6601 agagatatta gacgaataca tggagggcag caaatgatac cgagatttcg atcgtggtac
     6661 acaccattta aaggtaaaac aattggacaa gaaatgaaat atgggcaagc aggaaggttg
     6721 atcactcatg ctgaaatggc tccagataaa tatgtgctta tgcaatccac aggactgaaa
     6781 gataagaatg gcgtagaaat atttgaaggg gatgtagttc tggttaatgt aagtaatggt
     6841 tttgatcatt tagttaatga aaaaacggtt gtacaagaat ccgagtttca ttccggatta
     6901 gtttgtaaat cattaattag tggaatggaa tatagaatat tcagccacca aaagatggga
     6961 tacgaatatg aagtcaccgg aaatatacac gagaatagcg agttattgga ggtagagtga
     7021 ttatcttagc tactgactac atcgattctt taaaagatga aaatgggaat gtcccagcat
     7081 tgctaaattg tggaattaaa agtaagaata gaatcatttt gttacggata tcggctgatt
     7141 tagcaaaata tctttatctg agcaagacag cagtatatta cactgcggct acacgttatc
     7201 agtacaaggg aaaaacaatc agtcaggatt attatgatcg tttaatcagt cctgacatac
     7261 atggaaaatc aaaatcagcg atcaagttat ttggcgcaat agagatatat gccgatgatt
     7321 ttccaaattt atggttgaag gaggaacagt aatgaaagac tggttagaag aagcaagcgc
     7381 cttagttggc tgtttcataa actgtgcgtt tatatctgta attattgcac tggtgggatt
     7441 tgtatcattg aaagtgatta tattgctttg gcagttaatt ttttaggagg aacagcgatg
     7501 aataaacagg aagcaatcaa aaagttagaa agtattaaag tgataggaaa tgatgcacta
     7561 gctgcttgct ataacgagag tataaatgca ggtattacgt taatgaaaaa aatagacgaa
     7621 ccgaagaagc tagttattcc acaactcgtg gccggttggc ttgagaaatc tacggaccct
     7681 tttacgaaag ctgaaaaaat agcgtattta atcaaatcta aagatggtga ttcatattat
     7741 ttctgtgatt ggtttgtacg agatggcata gtgacgcaag aacaaggaga agaattactc
     7801 gcttgggcaa cgagacaatc atatgaaaca ctattgagct tgtacaacgg ctacgaggtc
     7861 gagaaagagc cgttgtacag tgtaataatt gctggcgagt accttgtcaa ggagatcagt
     7921 tgcagtaatg aagttaaact agtatcaaca gcttacctgc cacaatacct tgcacaccac
     7981 taccaactga ccgaaaaaca gatcaaagca attgatgaaa gatactggcc atttgctgtg
     8041 ccagtggaag aggtggcgga aggatgagta gacagataat gctccatata ccagacggaa
     8101 caaaggcaat gacgattacc attgttgctg cacaaaaaga cggtgggttg gcgttgaaaa
     8161 caaaaagcat tgataccaaa cagattttag aaggcagaga tgtcgagata gagatcgatg
     8221 aggaggaagc ggaatgaatg ttcaagttta tttaaaaaga gatttggcca ggtttcctcg
     8281 aagctgggat acaaattccc acccatccga ggcagaagaa gagggctatc taatgtctgc
     8341 taacatgata gaaattacaa gagatgatgc ggatgagttt gataaaaaaa gatcatggta
     8401 ctcggttccg aatccaatgt atacggctgt aatagaagat tatcatatat ccgacagatt
     8461 tattctgatt gatctagaaa ggcctaagaa acgaattaaa cagtatagac gttgtggatt
     8521 ttcaacaaag aaatggtgat aacaaaacag aggtgaagaa aaatgaacaa cagacaccgc
     8581 agagtagcaa aactaagaaa tcaagaactg aatgtagcga aagtaaagtt cgaacgggag
     8641 tatggtgttt ctgcagaaga aacatataaa gtggcaagtc agtgtgttgc tgatgcaagt
     8701 gatgctattc gtaagtttgg aatttcgata ctagatatta aatgggagga tacagaatga
     8761 agatttatgt agtaaagttt ggaaatcaat tttacagaag cgatgaacgt tctatagggg
     8821 ctaacacatt atccattgta gacatactcc aaagcgcaag atggtttgat aatctcgaag
     8881 aagctaacca agtttcacga cgacttggtg gattaacgca agtatatgaa ctggtcactg
     8941 tcgatcatga gggggtagag taatgaaact aaaagacgga ttttacgcta gtagtcatgg
     9001 tatcggcggt ttgatgctag atatgccgac aaagaaccct aaaacacgtg agaaaccaaa
     9061 attcaaagtc ggtgacatgg ttcgctgtga agcagaagga tttatctatc catttcgtgg
     9121 atatgtagaa aaggtattgt cgaactcagc aatcattcgt attgaaaaca cgatggaatg
     9181 tgacaagtgg ttagcgaaaa gcaaagagaa tttagctgta gcgagattag ttgacatgga
     9241 agtaatcgag agcaaataaa aaagccggat cgctccgact aacataataa aacagacaag
     9301 tttattatat cacataaagg agcggtttga cttgatgcaa ttgttacgag aggtagattt
     9361 caaacagaca agatgtaatg cgagagatgt gctgaagaac tttcggcgtt tggagcggat
     9421 ggcaggtcgc tctttgatag atattaagtc tccaattatt acggatatgc cgaaggcgcc
     9481 gaagcacggc aataaggcag aggacgcgat cattcagatg atggatatag aagcagagag
     9541 agatgcgatt ttagcggctt tgatggctct tagtctgatt agccgtcaga tactctacta
     9601 cagcttttgt gtgccagata gcttctcaaa ctacagaatt agccgtgaag tgggttattc
     9661 agaaagaagt atacaacgga tgaagtcgga agctctaata gagtttgcag aagcatataa
     9721 acacggaaga ataattgctt ataaataatt tggcggtttt ttggcggaat gatggcggtt
     9781 tttagctatt taccagtgat attatggtag tgtcgaaaga ttagtgatag gtctgagaca
     9841 aaataataat aaaaggaaca tcgttttatt attgtttcac aattaagctt cgatagacag
     9901 caacggaaat attaagaata aggatgtgaa tttcaactcc ttctaaattg ttcttattat
     9961 ctatcatccg ttgctgtcta ttgttttttt aattattcac acgataacta aaggtgagtg
    10021 aagagaaatg attccattaa taatttcaat ttttgcgctc tgtcttaatg tctatatgat
    10081 tggatttaaa aatgggcaaa ataaaaaata gtagcagcca agaataattt tatagtgtca
    10141 ctgtggcgga aagggtagac gcttaaaaat aaggtcaata cgtcgaggga tagccttaac
    10201 gttttatgat ttgaccatgc aatgttcgat tcattgccag tgactttggc aaccgagggt
    10261 tggaaatggg cgctcaaagt acacgagcaa ggcgaggtcg atagtaatcg atggaatcgg
    10321 tgtaggttgc ttgatagagc tataactgca tctcgtttat gaggtgtagt ttttacagat
    10381 tagatcactc tttgagtggt ctttttattt tacacaaagg aggtaacaag aatgtataga
    10441 ccacaatact tagaacagaa gtatgaagta atcactgtgc aaaacggtaa cggtgagata
    10501 gtacgaaagt atagaagacc aataaagagc gatacataca aacgaaagga aagcaatgaa
    10561 gttattccat tgtatggcaa aagaatagct aagcattaaa taagattgcg aaaggagacg
    10621 gaatatgacc gaggaattct atagatggct attacagttg ataagagaag atcgtttagt
    10681 taagttctat cagtctccta aatggcgcag gcttagagag aaagcgatga aacgagatca
    10741 ctatgaatgc caagagtgta gaagactagg taagtatcat agagtagaaa acgttcatca
    10801 tataaaggaa gtcaaggata gacctgactt agctttagat ttagataatc ttatttgttt
    10861 atgtgttgaa catcataatg aagttcatgg cagatatctt acagcattag ataaacaaga
    10921 gaagaagata gaaagctttg ctaacttcga tgcaagtgaa aggtggtaag tgcatgatca
    10981 tcaatgataa tggcagagag tatgatacag aaaagattga agagtattca tcttatactc
    11041 agggattaat taaacgtttg atatacgttc gctatgtaga tattagggat ctgttatcag
    11101 ataactgttg tagtaaatac aaagtgaatc aagtaagaga agcgttgaat aaagataata
    11161 acgtcgaaag aataaaaaat gtttttggat atagtattga agagattaat tattacattg
    11221 acttcgctga agctttcatt ccgatggtga gataaccccc ccttaaaata aatcgcaaat
    11281 tttttggggg tgatgaaacg gagggggctg tcaggaaaag agattttttc gaactttatc
    11341 atgaaaggag ggctaaaatg tttaaaaacg aattgtctca aaatcgctac agagaaaaat
    11401 tacgccgctc tttaataagc caattggaaa gtcagaaaac aaatattgag ccattcttag
    11461 ataatgttga tcgttatatc agtttatggg aaacggcgat atcactggaa gaagatatat
    11521 ccgagaacgg cattagactg gagaatggta aaaagaatga atcagtagcg ttgcttgttt
    11581 ctgtcaacaa acaaatggga ttgatgttgg ataaacttgc cattactcct gaattggtag
    11641 gtgaagcaaa tgaatcaatt cctgagttat aagcatattg aaaattggtt caaagctata
    11701 gaagaaggca ctatcaaggt atgcaaagag caattattgc taaaaaatta tctagaagaa
    11761 agagtcttta ctagagaaga tatttacttc gataagcaga tggtagagga ttcaatcaat
    11821 ataccagcac aatactttcc attcgaatta attccgtggg aaaaatttct acaatgtttt
    11881 atttatggtg ttcgatggaa aaaagataaa acactagtgt tcaatagata tctttcatta
    11941 atgggacgtg gtaatggtaa aactggtttt gcttcttgga acaacttctt tctactaacc
    12001 gctaaacacg gtattaaaaa ttatgatatt gatatctatg ccaataatga aagccaagca
    12061 aagactagtt ttgatgatgt atttaaagta attaaagatc atcctgattt agataaaaaa
    12121 gtatttaaag ctacgaagga agttattcaa aatatcgcta caaacagcaa acttcgttat
    12181 aacacggcaa atgctagaac aaaagatggg aagcgaccag gtgcaaaccg ctttgatgaa
    12241 attcacgaaa atgaagatta ttcaatgata aatgtggcta cttctggtgg tggtaaaatt
    12301 cgagattata gagaatttta tgatacaact aatggtcatg ttcgtggtgg tccgcttgat
    12361 gacattatag aagaatcaaa aatgattctt tctggagaac ttggaattga caaggatgga
    12421 gcagaatttt ctagtttgtt tccatttatt tgtcgcttgg ataacgataa tgaagttgat
    12481 gatcccgaca tgtgggaaaa agcttgtcca actattaatt acaatgcaga tttaaaacgg
    12541 aaaatgtttc aagaatactc tcaaatgcaa cgtaatgctg gtttaagact tacgttcatg
    12601 accaaacgaa tgaacagacc tatggaagat acacgatttg ctgttgcttc atatgatgat
    12661 gttctgcata cgaaagaaaa agaatttcct gaaaaaatgg atgaagtgat aggaacagtc
    12721 gattttgctg atagacgaga ttttgccagc gttgggttgc taggaaaata cgataaagat
    12781 gtttatttta cacaacatac ttttatccac gaatcagccc ttcgattaca aaacatcaaa
    12841 cgagaggtta tagatatttc tatagatcaa ggaaaatcac agatcgttca tggaaaaaat
    12901 atagaagctg attatattgt aggttggttt cttgaaatga gtaataaata ttatattaaa
    12961 aaaatcgcta tggatatgta ccgtgcaaaa atattgaagc ccgctttaga agaagcaggt
    13021 tttactgtgg aaattgttcg aagcggatct gttacacatg gtatgttaaa agatctggtt
    13081 gatgaccttt ttattaatca acgtttattt tttggtgacg atgcgattat gcgttggtat
    13141 tgcatgaatg tatatgaaga gcatatttct aatggaaata tacgctatga aaaaatagaa
    13201 cctgaaacta gaaaaacgga tggctttttt tcattccttc atggtttgaa ttttttagat
    13261 gatatttatg attctgctcc tgtaacagtc acaaatagct cagtagaaaa tacaggaact
    13321 ggatttactc ctctagtatt ctaacttgaa aggaggtgag aaagtgggga tttttcaaaa
    13381 ggcggtagga tacttcacaa aaaaagcaac ggttacttta gaagaatact tttgtaaatt
    13441 gcaagttgat tttgtgtatc gaaaatttgc gattgaaact tgtattgatt tgattgcaaa
    13501 tgcgatgagt aaagcggaat tcaagtcata tgaagatgga aaaaataaaa agaatgatct
    13561 ttactatagg ctgaatgtag ctcctaataa gaaaaataat gcaacagaat ttagaaaaaa
    13621 actgatcagg agattaatat tctacaatga agtattgatc gtttctccgt ctaataattc
    13681 tagcgaaata tttattgcgg atagttggga tgtcacagaa tatgcattga aagatgatgt
    13741 gttttctcaa gtgcaaatta acaacatagt ccttgataga gaatttctag aaagtgatgt
    13801 tatctatata aaatacgcag atcaacaaat taggcaacta gtcgatgcgt attatcaagc
    13861 gtatgggaaa ctcatttcta gtgccatgaa tgtttacaag cgctctaacg ctcgtagata
    13921 cgtactgaaa gggaatttat tccgaccgca agacaataca acacaagatc aaatcaataa
    13981 aatgatgaca tcacaattta aggcttttat ggaagctgat aatgcaggtg cggtatttca
    14041 attacaaaat gagtacacat tagaagattt cagcggaaac ttccaaagca attcaagaga
    14101 tataaaaaac ttaatagacg acatctttga gatgacagca gcagcgtttc acgttccgaa
    14161 aaacctacta aagggagaca tgagtgggtt atcggatcaa gtggacgctt ttttaatgtt
    14221 cgaaatcata ccgattgctg aacttattca ggatgcgttt aacgctagtc tctatgaagt
    14281 agaagaatac ttgtcaggga attttgtacg tgtggataca actatgatca agattactag
    14341 cttcaaagat ttggttgacg ctattgatgt aggcattaga aatggagtat ttacaatcaa
    14401 cgaaggaaga gaacgcgttg gaaatgatcg ctctgataag gcgatggcag atgaaatatt
    14461 tataactaaa aacaatcaac aagtatcgaa aggaggtgag gcgaatgacg acaatgaaaa
    14521 catttctagc agtaaagaat gaaggcgcag taccgcaaat ttttattcag ggatttattg
    14581 gttctagttg gttctttgaa gggaatactg acaagggaat caaaaatatt ttggatagtc
    14641 taggtgatca agaagaaatt gaagtagtaa ttaattcaaa cggtggagac gtatttcaag
    14701 ggattgctat tgggaactta cttaagtcaa ataaagcaaa agttaacgtt gtgattaacg
    14761 gcttagccgc tagtgctgct tcaattatcg caatggctgg cgatactata aaaatctaca
    14821 acaatgcaca attgatgatt caccgcgctt ccacatacgg agaaggaaat gtcgatgact
    14881 tccgtacgat tgctgaccaa ctggaatcaa ttgataaatc ggtaaaggct tcatataaaa
    14941 cacgattcaa tggcacagat gaagcattgc aagaacttct tgaaaaagaa tcgtttatgg
    15001 atgcagaaac agctttgagt tatggattgg tcgatgaaat tatcgatgca gaaaatagct
    15061 caggtactga agctaaaaaa gaacaaagcg ttgaagaaat tttgaatgac gttaaagaaa
    15121 aaagagcaga aaaaattgct gcatttacag cagcattaaa taaaacattt ggacaaggag
    15181 atgtaaaata atgacagtta aaaatttaaa aggtgtaaca gctgcaagcg accaattgat
    15241 gaaagctttt aaagatggta acgaagaatc ttttagcgca gctatggtaa gcttatctaa
    15301 ggaaattcag gataaaattt tagaagaagc aacagcaaaa aatcaagatc aattagtatt
    15361 aatgaaccgt ggtcagcgtg tattaactac acaagaaaca aaattctata acgaagtagt
    15421 gaaaaacgaa ggttttgcag gggtcgaaga attagtgcca gctactgtat ttgaacgtgt
    15481 atttgaagat ttagaacaat ctcatccact attgcaaaaa attacttttg ttaacacaac
    15541 tggtgtaaca gaatggattg tgtcacgtgg agtcaatcca gcatggtggg gtaaactttg
    15601 cgaagctgtt aaaaaagttt tagataatgg ctttgatgta attaacatga agcagttcaa
    15661 gctatcaggt tatattcctg tatgtaaggc aatgcttgat ttaggtccag tatggttaga
    15721 tcgttatgtc cgtactgttt tagtagaatc attgagaatt gcattagaac aagcaattgt
    15781 tgatggtact ggtaaagata tgccagtcgg aatgatgcgt gacatgagca aacaaactag
    15841 cggagaatat gctgaaaaaa aagcagaacc tattacagct ttagatgctg taactatggg
    15901 cggtttgatg gcgcgactat caaaattcaa tatcgaaggt gtgaatgatc cgatttatcg
    15961 taatgtgaat ccttctgatg tggtcctaat tgtgaatcca actgattact ggtctaaagt
    16021 attcccagct aagactgtac taactgctaa tggagaatac gtacaagtat tgccagtacc
    16081 agtttcagat ttgcagtcaa cggctgtgcc agaaggaaaa gcagttattg gggtagcctc
    16141 agattacttc atgggtgtag gatctacact aaaaattgaa gcttcagatg aataccattt
    16201 tgttgaagac gaacgcattt atctagctaa acaatatgca aacggtcaac ctaaacgtaa
    16261 cgatagtttc attgtattag atattagcgc tttgggaact actactacaa ctacaaaacc
    16321 aacaaccaca acaactacaa cacaagcgta ggtgatcaga atgaagtata ttctttgtca
    16381 gccggcaatc aatcggttta aatgggagct tgaagtttgt ttaactaatc tgaagaaact
    16441 aggaatcaaa gatatcgtat tgcttttcag cagacacgat gatcagattc ctattttttt
    16501 tgagaaggaa tatggtgttg aagttcatgt gtacgatgat ctgcgggacg acaaagagta
    16561 tattccttcg attaaaccat atttatggtg gaaatattta gaagaagatc attcgcgtga
    16621 ggacgaccga tatttctata tcgattcgga tgtcattttc aataaaagaa ttaatttgcg
    16681 caaattgcct tctaaagatg atgtttggta ttgtagcgac tgctgtagtt atctaagtct
    16741 tgattatatt agaagctgtg aaaacggaga aaatattcta aaagatatgg caaacattgt
    16801 aaatgttaca gtagaatctt tggaaactat aaacactaat tcaggaggcg cacagtgggt
    16861 tattaaccgc cctaaagcga attattggaa aaaggtttat ctggattcta atcggctata
    16921 tcgctacctt agagggcaaa aaacaaatat aaaaatctgg acagccgaga tgtgggcaca
    16981 gctttggaac atgatgtatt tcaatattgg tcctaaagtt cacgaggaat tagacttttg
    17041 ttttgctact gatccaatag aaaaagttaa agaagtaaaa atcttacaca atgctggagt
    17101 aacaacaaac gatgaagatt tatttttcaa agggagatac gtgacttcta cgccttttga
    17161 tgaagattta tcatttgtaa acaagaaaaa atgctcttac gcatatgtta aagcaattaa
    17221 ggcggtggtt agatgacgcc tgaacaagtg actgaagaat tgctaatagc tgtgaaggat
    17281 aatatttacg ttacctggaa cgaagaagat gagtcaatta aaaagatgat agctaaaaat
    17341 gctgtttatc ttcaaagtaa agtgagtaca acactttctt tttctcctga aagcttagaa
    17401 tacggattgc taatcgaaag atgtagatac gactggaatc gtgctttaga tgagtttgaa
    17461 caaaatttcg ctagtgagtt attaggtttc attcaacatt atgcgctaca agaatatatt
    17521 gcaggtgatg tgaatggcga ataatcgtag actcgaagaa acattcaacg atggttggtt
    17581 aaagattttg acgcaaacta ccaaaagaaa tgaactagga aaaaagattg gtgtagaaga
    17641 tacagaaatc acttctttaa aatttagaaa tctttccatg agagatagtg atataacagc
    17701 tatggatgcg atgggatcga aattaactaa gaaagtaaag actccatttc atccaatcgc
    17761 caagaaattt aataaagatc aatattttat cgtaatcgat agtatgcgtt acaacgttat
    17821 ctatgccgat tacgataatt tttatatcta tttttatctt gaaagtgtgg gtgaatatgg
    17881 tgattgataa ttctaaagaa aaagaacgtt taaataagca aatttctgct atcaaaactt
    17941 ccttagaaga gcattttggc ctcaaactct ttcaagactc cgtaggcgag gatgagctac
    18001 ctgatgattt taattacttc attctcgaaa caggagaaat agaaatgatc actgagccaa
    18061 aatatagcgt gggtcaaaat ctatatctaa ctttctattc agaaaataga gaagatttaa
    18121 caggagattc actagatatt atttcattga ttcaaaatcg ttcgattcgt tttcagagaa
    18181 tggatcccaa tcatttaaaa ctagagaacc aagatcgcta tatcgatcaa ttggtattta
    18241 cgtttagacg attattgaag agtgattgtc atggctaaaa atagttggga gctaaaaata
    18301 aatggacatg atgaacttct tgtgcggatg gaacgctatt caagcgagag cgaacgactg
    18361 attaacgaag cattgaaatc aaaaggttcg gctattgcag tggataggat tacagaaaaa
    18421 attcctgttt ctgaagcaga tttaagaaga gggcaccaac acgcaaaaaa tagtcgtcca
    18481 cttaagactc aatacattaa tttgggtttc atcattagac ctacaagaaa atttgagtat
    18541 ttaaaatatc ctgatttggg gataggtact tctaaaagaa atcagccgga cgaatttatg
    18601 agaagaggat taggtcttgc acttgatcca attacagaac ttctgattcg tcaattcgat
    18661 aaattaaata aataggagga acaacaatgg ctaaaacaac aacagtaaca acttttgaca
    18721 atataagtat taaaagaatt tcttttaatt ttaagaatgc aacaaatgca atttcaactg
    18781 attgtaatgg acaattagat ggcgaaacag aaatgcagag aattgtaaaa aaatgcggtt
    18841 caacagaagt aaaatcgaaa tctaaaccaa tcaatatgac ggtaacaatt actgcacatg
    18901 taccgatgga agtttatcga cgcttcaatg ggttgaaaca agatgaacgt attaaatcgg
    18961 gaatttactc ttatggtcct gattccgtag gggaagattt ctctcttgct gcagagatcg
    19021 tggatgattt cgaagaaaaa aataagctga ttggtatgtt agcatgcact tcgaatacag
    19081 gattaacatt ctctattgaa aatggtgcgg atgaagtagc tgcgttagaa ctagaaacaa
    19141 aagttatgca agatgaattt ggtaaatttt atcatgaagc aattgttgca gaacttgaag
    19201 aagacttaac agatcaatgg atgacgaatc tatctgctga tgtgattaaa aaaacttcag
    19261 ttgtgacaac tacggccact caatcacagt aaaaaaaacg gaggtagcga aatgaacgaa
    19321 gattactcaa aaattgaact aaacgatgga acaattttga atttagaacc taaactgaat
    19381 atcaagaaat tattgatgat caatagagat tttaacacag acgagtttgc aaaaatgtcg
    19441 atgggaaaag gctctatgga tattacagtt attcaaggtg caaaagccgt atatgtagct
    19501 tatcgtcaag cgaacatggt cgattacatt tcattcgatg aatttataga taaatgagat
    19561 tttgatatgg aggttgcagt agctgtatac agtactatga tgttcaaaca agcacgtgat
    19621 gcctatcaaa aagaattcga aaaagcaaat aaggaaaaaa agcttcaaaa gtaaaaatgc
    19681 caaagctctt agttgaaacg tgggtcgatg tctattcgat gttgaccgac gttttttcta
    19741 tgccttcaga tttggtttta agcgatatct gtttagatga cattttgcaa atggcttaca
    19801 acaagagcgc ttatgaagga tggaagaact atgcaataaa tcaatcccag aaaaactaaa
    19861 ggaaaggagg taaaaaatgg ctaaaaagag aacggaagca gaagtaactt tcatagctaa
    19921 cgatgacgga ttgaaatcta cgttaaaaga aatcagtgct gaattaacta aaaatagagc
    19981 agaattaaaa ctagaacaag ctcaattgca acagactggt tctgaatcag acaagttagg
    20041 aagtaaatta tcttctttag aaaagcagta tgaattacaa agtcaaaaag ttgaagtaac
    20101 tagccaacgt ttagccaatg cgaaaaaata ttatggagaa aattccaccg aagttcagaa
    20161 acttgaaaga gaactgatta atcaacaaac agcgcaacaa cgtttgtcaa acgaaattga
    20221 taaaacgagt aatgcactag ctcaagcaaa aggcgaaata cagacgtacg agtctacaat
    20281 gcaacagttg gatagcgaac aaaaaaatgt tcaagctagt gcttctctga ttgaatccga
    20341 atacaaaaaa tggcaagcaa ctgctggtca atcagcttct gaagccgaga aattagcgaa
    20401 agcccaagaa tatgtttctc aacaatctga aaatgcggag aaaacgatag atatcctaag
    20461 acgacagtta gaagctacac agtctgaatt tggcgctaca tccacagaag caatgcagat
    20521 ggaagcgaag cttaatgatg ctgaacgtga atttgaagag ttaggacaag ctgctaaaaa
    20581 tgtagataca actaacttgg acgatatcgg aagcaaaata gatatgaata atttaatgga
    20641 agcttctgac gttttaagcg acattggcga taagcttaca gaattaggga aacaagcagt
    20701 ggactctgct aacagtgtag gtagttccca gagtaagata caagctaatt ttggtttgtc
    20761 taaacaagag gctgaagaat taacgaatgt agccagagac atttattata aaggttttgg
    20821 agaatcgtta gatcagtcca cagatgcatt gattttggta aagcgtaatt taggagattt
    20881 aaataatcaa gatttacaaa atatcacgga acaagctatg gtcctagaaa acaccatggg
    20941 cgctgatatg gatgaaacgt tacgtggtgt aaatggctta atggtcaatt tcggcttgag
    21001 tgctcaagat gcaatggatt taatggtttc gggtactcaa aacggtttag ataaaacgca
    21061 cgaattaggc gacaatatgg cagaatatag ccaattatgg agtcaaatgg gatattcagc
    21121 tgatgaaacg ttcggaatgc ttcaaaatgg tttagatgcg ggtgcttata accttgataa
    21181 agtcaatgac ttagttaagg aaatgggaat atcgttaaca gatggtcgat ttgagcaaaa
    21241 catggatatg tttagtgaaa gtactagaaa agcttttgaa gagtggaaaa atggcggagg
    21301 aacacaaaaa gacgttatta attccatgat tcaagatttt agcaatatgg atggtcaata
    21361 cgaccaatta aataaagctt cgacaatttg gtctgcgctt ggcgaagata atgcgatgaa
    21421 agttgtccaa tctttaactg atgttaacca tacatttgat gatgttagtg gatctgcaca
    21481 aaaaatgaat gaagattcta ctactccgtt acaagaatta aacggaaaaa tagctgaatt
    21541 aaaggattca ttagctccta taggcaacac aatcatagat gcactcgaac cagtaattga
    21601 ttttctagga aagatggctg atgcgtttaa taatcttcca caaccagtac aggattatgc
    21661 cgtagcgatt ggcggattga ctgctgcatt tactttatta atgccaataa tagttggctt
    21721 catggctcta ggtggtccta ctacattaat aataggagca gttattactg ctattgctgg
    21781 agttatagca attataaaaa actggggcgc aattactgac tggtttaagg gaatatggag
    21841 taaattcact gattggttgg gtggtacttg ggaaagtata aaagaaggtg cctcatcagt
    21901 ttgggatgga gttaaagaaa cctggtctgg atttgtagat tgggttcaag atatttggca
    21961 aggagtttct gattggtttg gagagctatg gagcggatta gttgaaggag cttccaacat
    22021 ctggcaagga gtccaagaaa cttggcaaac attcgttgat tgggtttcaa atatttggaa
    22081 cggagtcaaa gaagtatggt cgattatttg ggcagacatt gtaggaattg ttcaaatacc
    22141 atggacatta ataacgtcat tgattcaagc tggtattaat attatcgtgg gtatttttga
    22201 tgtagctgga cagttattag gcgcagcttg gcaagctgtt tggacaccta tttctgattt
    22261 ccttaaaaat acttgggata ctatgacaca atggataagc atcgcttgga acggaattgt
    22321 aactacattc catactatat ttgatccagt agtggcatgg tggaatggta tatggacatc
    22381 tattagtact acggcttcaa atatttggaa ttcaattagt gcaacagctt ctagtatttg
    22441 gaacagtatc aagaatacaa tcactagctt ggtacaagca gctgctacag taattcaaaa
    22501 tatttggtca actgtatcta gttggttagg tggaatttgg aattcaatca gctctacagc
    22561 atcaaatatc tggaatagtg tgactagtag tataagcaat gctataaacg cagctaaaag
    22621 tgccattcaa agtgtttgga atagtatatc ttcgtggatc agcggaattt ggaacggtat
    22681 caaaaacact gctttgaatc tttggaatgg aattacaagc actattagct ctaaagtaaa
    22741 cgatggaaaa aatgcaattt caagcggttg gtccaatcta acaggtattg tttccgacat
    22801 attcaataat gttaaaagta caattgctaa catttgggaa ggtatcaaaa agactgttag
    22861 cgctccgatt gattggatta gagataaaat cagtggcatc tttgataatt tgaatatttc
    22921 gataccacat attccgttac cacattttaa attgagtggg gaattcaatc cattgaaggg
    22981 aaaaatccca acgttgggtg ttgattggta tgcgaaaggt agtgtgttta attctccgaa
    23041 tattatcggt gtcggtgaag caggacctga agcagtttta cctttgaaaa gatctgtttt
    23101 gcaagaaatt ggtgatcgta tcttgagtag cacatcagtt tcatctaggg cacaaacgat
    23161 tcaacctgtg aataactacg aattcaattt cacaattgat ggtaacgcag atgaggttac
    23221 tatgaagcaa acaactcaac aaatcattga tagcattaca aaaattcaaa atgataatgc
    23281 ttcggcatgg cgttaaacag gagagtattt ctcctgtttt tttagtatta aaaaggatgt
    23341 gaaaaaatga ctgattgtat acattctata atcgatggat ttcctgatta tttgcataaa
    23401 ttggctttag ctgaaagacc aaccatacct tctccaaaaa gacagagagt tgaaacttct
    23461 gttttaggta ggttaggtgg cttagtacaa gattactcgt ttgaagatat gtcgtttaca
    23521 ttgcactata actatttaga ggatgtggaa gaccatcaag cgttcaagca atcgttttat
    23581 atcatgcgtc attggttaaa ctatgcaaag aaattagaat tctctgacga tcccaacgtc
    23641 tattacgtta tccagactat cgatattggg gatgcagaaa acgatattgt tgaatgggga
    23701 gagttcgatg taaatattac tgcgaaacca ttcgcaagag ttcaagaaga tgtacctata
    23761 accgtagata aaccacagtc atttaacttg ctgaataata gtttagaaga aagttttcca
    23821 aagattatca tcactccttc agctacttca tgccagttca tcttaaatga ttatgtgttt
    23881 agtttcgaag gcttagtagc aggaactgat gtagtcattg atagtgattt gatgctttgc
    23941 tacgaagagc aatcggacgg agatatttta gatcggtcca acaaaatgaa gaccatgcaa
    24001 tatccaacgt tgcaagtgga tattaatcat tttaattgta ctggtttgag caaaatacaa
    24061 atttatcgta acgggttaag gtaggtgaaa tagatgatcg ataatttaat aactatttac
    24121 gataaaaatg acgcgaataa tttagctgaa catttatatg atacgcaagg tttaggcgct
    24181 ttgtcagact ggttaacagc tactgttagc aataaactaa acggagccga gatatttcag
    24241 ggtacttatt caataaacgg aactaatgca gatttgattg tagaaggacg tattattcag
    24301 tgttatgtag atgaaaatcg agcaaaacag cgtctacgga tttattatgc aaaaacttct
    24361 gtaataggca atacgataga agtaaaagct gaacctattt tcaatgatat aagaaaatcg
    24421 gtgttgaata aatatgacag cggaacagaa aagatcactg ctactcaggc atggcaaaac
    24481 gcaaaagttt tagcgaaacc agctatccct tcgcagtttt ctttctcgtc attagtagat
    24541 acgcttgcta atgtgaagat agaaaaggcg aattttttag aattctttgg tggaaaagag
    24601 ggatctattc tagatcgatt tcatggtgag tttctaaaag ataataacac attacgtcat
    24661 gaaaaaagtc taggtacgga tcataaaatc aaagcgattt atactaaaaa cttaactggt
    24721 cttgacttag agattgatgc tcaaagtgtt ttagttggag tttatccatt cattagcagc
    24781 tcttcagaag gagaagacga gatcactcta ccagaagaag ttattttcac ggattacgtg
    24841 gatgattatc ctgctggata tgtttctttt gttgatttta aagacaaagc gactgatgta
    24901 gccacattaa gggaagctgc taaagactgg ttgaaaacaa acatagataa acaaaaacca
    24961 caagtgagtg gttcgattga attagtacca ttgaggcatc aaagaggcta tgaaaaattt
    25021 gttgatctag aaaaagtttc gatgggtgac ggagtagatg tgtatcatcc acagttaaaa
    25081 gtgaatatgt cagcgagaat tgtggaatat acgtttaatg ttctaaccaa ttcatacgat
    25141 aaattagttg taggaaacgt caaaacaaac ttcttagaaa acacagagaa taatgtcagc
    25201 aatttgatta atgatgccat tgatcaattg aaaaatggtg gcgaaatcag tgatttaatc
    25261 aatgatattg tagatcatca aactgatatg attactggtc aaaatggtgg ttacgtttta
    25321 ttagatccta aagaagcccc tagtcgtatt ttgattatgg acacaccaga taagaatact
    25381 gcacggaacg ttttgcaaat caacaacgct ggtattggtt tctctaaaac tggcattaat
    25441 ggaacgtatg acaccgcatg gacgttagat ggcggattca atgcctcgtt tattacagct
    25501 ggtgagatag tagggattac tattagaggt actacattaa ttagtgatgg cactgattat
    25561 agaacaagta tagctaatgg caaaatgact tggtactcaa aaaaagttaa caaagatatt
    25621 atggagctag aagcacgtga ttatgtaagt gctgatgcag gtattgtatc atacaccatg
    25681 aaaactggtg gtggtttcat gattagaaat ccacagggga atttggtttt tagtacgtgg
    25741 gataatggta ataacaaacc gtttttatct tttggtgcgc ccaatttcag gtatagcaat
    25801 gctagttata taactgatgg cgatggtagt tctttaagca ttaatggtag tgcgggcagt
    25861 tcatgggagt ttaaagtagc tggtaggact atgaaattta ctagtgatgg tatgctaacg
    25921 ttgccaggtt gtttttttgg ttcatgggaa gatggaaaac ttgctaggtt tgaacaatca
    25981 acggtacaag tatataaaaa ttttactgtt agaggtacta aaaactcaac cgtaccaaca
    26041 gaacattatg gacaacgact attaaacgct tatgaaactc cagaatatta tttcgctgat
    26101 tatggggaag ccgttacagg tgatgatggt aaagttcgtg ttgatattga tcctatgttt
    26161 gccgagacag taaatctaag tcgatatatg acacatgtga cacctacaga gctagttttg
    26221 tgtgctgtta ctcatgaaga tattgaccat ttcatcattg aaactagtaa gccaaacgta
    26281 ttggttagat ggaatttagt ggcacatcga ctagggtatg aagatgttag attaaaagag
    26341 gatacagcat atgatagcac agtgcttgac caaaaacgtt tttaaaacga agacaaggag
    26401 gtatataaat ggctagcagt ttatataatt tggctttaga tttcagcaaa gaattaaact
    26461 acaccaaagc tattatggct cgtcaaggtg acaaaggaat tacggtgact gttaaaccgt
    26521 ttttaaatgg cttgcagatg gatacgagtg gcggaacctt tacattaaaa ggaacaacac
    26581 catctaaccg ttacgtagat agtgtcgcta ctagtataac tagcgaagaa gtcacatttt
    26641 ctcttgatgg aacatttatg agtgaagcag gatactataa acactgctac gtagaatata
    26701 gaaaagataa tcaaatttta acgacgcaag atatcatttt tttctcacta ggagtgtctg
    26761 acatttcgca aggccaagcc gatgaatatg tttcgcaatt agaagaattg attcgaaagt
    26821 ataacgaaac ttttgatgct tttctggctg aaattaaagg tagaatggat agcttaaata
    26881 aacagattac tgatttaact ggtcaagcta aaacactaca agacaagtta gatgctctga
    26941 aagaagaaat ttctaaatta ggtaacttac atgtgatgta ctccaacagc atcgacttcg
    27001 ggggctatga ttatagtggg aatccgaatt taatgtccaa actaaaatcg agcgatttta
    27061 acgttggtta ccacgggtca ctaactaatg ttaacggaat gttacatttt atgtctgatg
    27121 gtacagggga cattgatatg tttacgcgta ttaatacacc tcagcttgct agtgggaaaa
    27181 cctatactct gagtgcgaaa gttcgatttg atgaaggaac tacaggagct attgataaat
    27241 tacgtttggt gtatcgtaca tcaccaggag aaaagatatt attggaagca aatagtacaa
    27301 atattacaac agatgatgta gggaaagaaa taacaatcaa aggtacagct aacgttaatt
    27361 atcaaatcac aaatttagat cgattttata ttagtgttag tttttctaac agggataaaa
    27421 taaatggtgg atttaaattg tacgacatca aaatcgaaga aggctcaaca gccactccgt
    27481 atcagccaaa cttactagat gacccttact gggtaggtaa aacatcgttg ggtaagaata
    27541 ttgcaaataa aggtacgacg ttcccaatta aatctagcgc gtacgaaata tataaaggta
    27601 acacggaaga agagcttata ataggtcaaa cgtatactat cacgcttaaa ggaacaaaac
    27661 ccgcaagtca aacctttgta gcatataatt attggaacgt taattttgga gatctaaaac
    27721 cagttgaggg attgacagac gtatggtctc taacattcac accaacgaaa cttgaaccgg
    27781 gtttgcctaa agaccttcgc atttttcagt cgcctaaaga aacggccggc gcatgccgaa
    27841 ttgactggct caagatcgaa aaaggcgaca cacgaacccc gaatattgag caatataaat
    27901 accgaggaat cggcatgcga gactcaaaca atccaaaaga ttatgtatgg gatctagaac
    27961 ctagctatgt tgagaataac ctagctacag atatcaaggt tgctgaaatc acaggtaaag
    28021 caaacaatta taccgatggg aaagtatcgg agattaattc gcagttgact gcttcaatta
    28081 atgaagtaga caccacagct aaggatgctc aaacaaaagc gaatgctaat gcgactgcta
    28141 tagatgaatt agacaataag atcgatgaac gcattaatga tacagctact accacattaa
    28201 cagttacaaa cgggaatacc ggatcagcaa agctttatcg tgaaggaaaa acagtttcta
    28261 tatattttgt ggctttaaac ggaaaacgca gtggtggaaa tgattcaacg atactaacaa
    28321 ttccagaagg ctatcggcca ccaattagtt ttgagcaact ggttggctcg atagaccgtt
    28381 ctactttgaa cagtgctcag ttatctattg gtgcagatgg agccattaaa tggcgaagaa
    28441 actcaagtta tggatcggat tatacctttg caattactta cacgatttag aaaagcgtga
    28501 atcgatatga aggcagcata tagaccaatt gaaccttacg gattcgagca aatcattgtg
    28561 aatgatgaag aacatttacc ggaagaatgc acagaagtcg aaccaccgat tccaaattgg
    28621 aaaccgaaat tcaattactg ggagggaaat aaatgaaaaa catttggaaa tatggacgta
    28681 ctggcggaga gtacgcagga aaagtattgg acgacatgct tgtatccgtt ccttacacag
    28741 atcagccacc gcttgaagga attcgtgctg atggcgaacc gttaacaatc gctgatcaaa
    28801 tgtttgatcc taaattgaat caatggatta ttttagcgaa cgcactagat cacaacgatt
    28861 taaacaatct caaagcaatg tatgagtcgt tagaaaatga gaacggcgat ttaaaacaga
    28921 tcaatgccaa actcatgcta agcgatgtag caattaaaca ggaaaatact gcattgaaag
    28981 aaaaagcgga tagtttagca caaatcaatt caaaaatgat gcttgcttcg ttacaaaata
    29041 gcaaagacat ttcagaaatt aaagagcaac taaatccagc ttcaaaggga ggtgagtagt
    29101 atgtttagtt ttagcgatgt gaaaatgatg tatgattggg gctgtttcac taacgaacaa
    29161 gtaatggttt tcgttccgtt gtgcattact gaagaa
//
LOCUS       DADGHT010000027        28690 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.027, whole genome shotgun sequence.
ACCESSION   DADGHT010000027 DADGHT010000000
VERSION     DADGHT010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28690
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.027"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(20..964)
                     /locus_tag="JX887_001075"
     CDS             complement(20..964)
                     /locus_tag="JX887_001075"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAX1257080.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1260..2204)
                     /locus_tag="JX887_001076"
     CDS             complement(1260..2204)
                     /locus_tag="JX887_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1257081.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2425..3639
                     /locus_tag="JX887_001077"
     CDS             2425..3639
                     /locus_tag="JX887_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1257082.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            3661..5676
                     /locus_tag="JX887_001078"
     CDS             3661..5676
                     /locus_tag="JX887_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAX1257083.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(5759..7132)
                     /locus_tag="JX887_001079"
     CDS             complement(5759..7132)
                     /locus_tag="JX887_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAX1257084.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7158..7442)
                     /locus_tag="JX887_001080"
     CDS             complement(7158..7442)
                     /locus_tag="JX887_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1257085.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7444..9459)
                     /locus_tag="JX887_001081"
     CDS             complement(7444..9459)
                     /locus_tag="JX887_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAX1257086.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(9638..9943)
                     /locus_tag="JX887_001082"
     CDS             complement(9638..9943)
                     /locus_tag="JX887_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAX1257087.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10032..11063)
                     /locus_tag="JX887_001083"
     CDS             complement(10032..11063)
                     /locus_tag="JX887_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAX1257088.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11270..12145
                     /locus_tag="JX887_001084"
     CDS             11270..12145
                     /locus_tag="JX887_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAX1257089.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12297..13139)
                     /locus_tag="JX887_001085"
     CDS             complement(12297..13139)
                     /locus_tag="JX887_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAX1257090.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13231..15108)
                     /locus_tag="JX887_001086"
     CDS             complement(13231..15108)
                     /locus_tag="JX887_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAX1257091.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15105..16526)
                     /locus_tag="JX887_001087"
     CDS             complement(15105..16526)
                     /locus_tag="JX887_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAX1257092.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16529..19918)
                     /locus_tag="JX887_001088"
     CDS             complement(16529..19918)
                     /locus_tag="JX887_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAX1257093.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20175..21566
                     /locus_tag="JX887_001089"
     CDS             20175..21566
                     /locus_tag="JX887_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1257094.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(21639..22286)
                     /locus_tag="JX887_001090"
     CDS             complement(21639..22286)
                     /locus_tag="JX887_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1257095.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22294..22980)
                     /locus_tag="JX887_001091"
     CDS             complement(22294..22980)
                     /locus_tag="JX887_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1257096.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(22986..24059)
                     /locus_tag="JX887_001092"
     CDS             complement(22986..24059)
                     /locus_tag="JX887_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAX1257097.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24281..24955
                     /locus_tag="JX887_001093"
     CDS             24281..24955
                     /locus_tag="JX887_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1257098.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            24960..26300
                     /locus_tag="JX887_001094"
     CDS             24960..26300
                     /locus_tag="JX887_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1257099.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26449..27435)
                     /locus_tag="JX887_001095"
     CDS             complement(26449..27435)
                     /locus_tag="JX887_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAX1257100.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            28159..>28690
                     /locus_tag="JX887_001096"
     CDS             28159..>28690
                     /locus_tag="JX887_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HAX1257101.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFE"
BASE COUNT         8453 a         5398 c         5177 g         9662 t
ORIGIN      
        1 agttcatatt cattgtttct tataatacag tgttcaatac ttctcttaaa gcacttgttg
       61 atttgctgaa cattgctttt tcttcttcgt tgattgataa ttcaacaact tcacgaacac
      121 cattttcgtc aacgattgat ggcacacctg taaagatatc tttttcgtcg tattcaccag
      181 ttaaataagc agatacaggc aatacagctt gttcgttatt caagatagct tttacgatac
      241 gtgcagtact cataccaata ccatagtaag ttgctttttt acgatcaatg atctcataag
      301 cagcattacg gactttatca gcaatcacat ctaattcatc ttgggcaata cgatggtctt
      361 tttctacaat ttcaaacact ggtttaccac cgacagttgt atgtgaccat gcagcaactt
      421 ctgaatcacc atgttcacct aagatatagc cgtggacgct gcgtgggtca acttttaatt
      481 tcaatgcgat ttctttacgg aaacgagttg tatccaatgt tgttccagta ccgataacac
      541 gtgatgttgg cagaccagat tcgttccaag cgatatatgt caaaatatct actgggtttg
      601 aagcaacaac gataataccg tcgaatcctg atcccatgat ttcttttacg atttggcgca
      661 tgattgacgc atttgtttta actaaatcta aacgagattg accaggtttt tggttgatac
      721 cagctgtgat aacaacgata tcagcatctt tacattcttc atagccacct gaccatacag
      781 ccacattttc atcgccccaa gccataccat ctaaaaggtc caatgcttcc ccttctgctt
      841 tttcttgatt cacatcgatc aatactaatt cattagagat tccttggttg atcattgcat
      901 aagcgatact tgttccaaca aaacctgtac cgacgattac tactttacga cttgtttttt
      961 tcatgaataa acagctcctt ttcataacta tttgttactt tcatgaaaag tatagtcttg
     1021 tttattcatt ttatcaacat gttaattata atagttgtta ttataatttt tgatggaaac
     1081 gaattcctga atacgcataa cagataaatg acaaatgttt acacctatat cccctgataa
     1141 tacaaccaaa agtttagaac tgaaaataaa tccaaaaaaa ttcgctgcaa cgatataata
     1201 agacagcaat cgcacctaaa acaattttcc ttcatatgct ttagtgaaag attttcttct
     1261 taatgtttat ttctccattc attgggagta catgttgaat acttcttgaa taatttgaat
     1321 aaagaagtcg tttgtttata tccgatacga ttagcgattt cttccaacga aaaactcgtt
     1381 tcttgaatca gttccaacgc aaagtcgaat tttttcttta gaaccagttc ttgaaaggaa
     1441 gcatcaaaat acattttcaa tttattacta agatagaccg gattgtagcc aaaatgagct
     1501 gctgtttctt ttaacgtaca agaagtaaaa tgcttatcga tataatctaa tactctaagc
     1561 atctcatttt ctgcgcatcc atctgctgat gaaaagcttt gttgttctaa taaatgagtc
     1621 aattcgatca gtaatagtga tgtatagaga tttaacgaac ggatcttatg actgtatgta
     1681 tcaaaataaa tcaacagcat attttcaatc aaatgcgtca aacgacttgt ttttccgccg
     1741 cgaaaatgaa tgaattgtgt atgttcccct ttttcttttg atgcatttat caaaaaagaa
     1801 gaaagtagat tatttgtgct tgccaaatga ttcaatatct ctgtagataa ggtttcttct
     1861 tttaataaga tgttgattaa aatatcctct tgccctgtgt attcgattct ttgagtagct
     1921 tctttatcaa tgatcaccac gtcactttct tccatctcta tcctttctcc attaataatt
     1981 tgtaaacatg taccgctata catataattg atttcaacaa aatcatgtgt atgctcggga
     2041 acttccgcat atcgacggtg tttactgata tgaatatttc cctgttgaaa tagatcccct
     2101 cggtggattt ttggcggtgt ctgaagatgg taagctaagt ttaaatcatt gatattcatt
     2161 ccttgttcac gctgcagagt ttcgattgat tcttcgttac gcaaaaaaaa tgtctaattc
     2221 agctagttcc aattgactcc ctcctttttg taagcggttt ctttcgctta ttagttcacg
     2281 ctgtactgct attatatgca aagctatttt tggtttcata aagactttct atggttggga
     2341 catgaacttc ctgtgattcc gctattgaga gaataaccac ttcatactat atttttgata
     2401 agcgcttaca aaaatgaaag gaacatgctt atgaataaaa agatgatgaa attttctctg
     2461 ctgtcagtct ctcttatttt gacttctgct ggtgcagtca cgtctgcaat tcccagtatg
     2521 tcagctactt atgccacgcg ttctttatct gctgttgaat tattaacgac tgctccctct
     2581 tttatggtca ctatttttgt tttgattagt agttttattg ctaggaaaat cggacaaaaa
     2641 caaactgtga tcatcggatt agtgattgca tcgatttgtg gtatcctccc cctcttctca
     2701 caaagttaca gtattgtctt agcttcaaga gctggactag gtattggctt tggattgatc
     2761 aattctttgg cagtcagcat gattgctgcc ttttatcacg gagatgaacg agcctctatg
     2821 attggttttc aaagtgcatt tcaaggattt ggtgcagctt taatgacatt tgttgcagga
     2881 cagctagtac agttcggttg gcaatatacc tttttagtct acgccatcag cttacctatt
     2941 cttgtcttgt ttgttttgtt tgttcctaca cctgaaacaa ctgaacttca atcgcatggc
     3001 acagccccaa caagacaagt aatcaaaacg aatcctaaaa tgattagtta tggtattttt
     3061 ctcttgctgg tcatcgtggt atataatgct gtatcgatta aattagccac agtcctgacg
     3121 acttattctc taggaaacga aactaatgca gcgaatatct taacaatcat gcaattggca
     3181 agtatggctg ccggagtttg ttttggctgg cttcagacaa aagcacatcg ctatatgctt
     3241 acactttctt tactactgat gggaatcggc tttgtattga ttgccactgt gataaacctg
     3301 tatgtgattg ggtttggtgc gatcctaaca ggaatttctt tttcgttatt cattccttac
     3361 ttattcaacc aagtaagtat ccaagcgccc aagtacgcgg agagtttcaa tacttcaatc
     3421 ttattggttg gcgctaattt aggtactttc attgcaccat atggtttgct ctttctctct
     3481 tttgcttctc ttgggagtaa aacacttgct gttttcgtca atggcagtat cttgctgttg
     3541 attagcgcgc ttattagcct tctagtagta cacaggacga atagaaagac agtgataaga
     3601 gtagatgaag aaataaaaga acaattgaca acaaaataaa tttgatggag gtcgtgtaaa
     3661 atgacaaatg aaaaacataa agatagatgg ctttggtatc ctggagactt tgagatccgc
     3721 catggactgc tacaaaattt ccaacgggaa gaacgaggtt ttgactggcc agcgtactgg
     3781 tacatggatg attgccatcg gaacgtcaag tttaagagat attactttct tgatcaacct
     3841 tccatgttta aagtgacgat ccaaggagtt gggtatgtag aaattaatgg acaaaaacat
     3901 ccatgtggaa aatggctgac ttgtccagct ggtaaagcaa aaattcgtat ctttgtagga
     3961 catacatcag ggctaccagc gatgtttatc gagggagacg aagtaaaatc agatattggc
     4021 tggacagcaa gtaattttat tgaagaatat ccagctggct ggagtccgct ttatgtcgat
     4081 atcgcaaaag atccaaatca aatctattat caaaaagaat gcgtccatcc agtcactgaa
     4141 acggagattg gcggaggaat cttattcgat tttgggcgag cagtgaatgg ctgtgtagaa
     4201 ctaatatctc tggatgacca tatcgaatct atcactctat gttatggaga gtccgatgta
     4261 gaagctatgg atatcgatta ttgctactat aagcaaatag gaatgacaag aaaaatgaaa
     4321 gctcgtaaac gcgcttttcg ctatttgttt ataccagagg tttctactgg aatggttcaa
     4381 cttcaagttt ttcatgaatt tttatctctt tcgaaacaag ctgctttttc aagcgattct
     4441 tctttactga atcagatctg gtcagtatca gaagaagcct tcaagttatg tagtgatttg
     4501 ttttttatcg acggtatcaa acgagatcgc tggatttggt ctggagatgc gtatcaatca
     4561 ttcatgatca atcaatatct tttttttgac gaggaaatca ataaacgaac gatattagca
     4621 ttaagaggac aaaatgaaat caagcagcat atgaatacta tcgttgacta ttcgatcttg
     4681 tggttgattg gtatcgaaaa ccactatatg atgacgaaag actatgaatt tttacgcatc
     4741 gtctacccta agatgcaatc attaatgaga tacttgatgg agcaaacgaa tgaattaggg
     4801 tttatttatg ggagagcaaa agattggata tttattgatt ggtctgaaat ggataaagaa
     4861 ggaacgcttg ctgcagaaca agtcttatta ctgaaagcct atcattccat gatcacttgc
     4921 ggagatatct tagctgaaac atatggagag aacgaaaatt atcatactca tctctatcaa
     4981 gaaaaatatc aactattgaa acaaaaccta tttgactact tttgggatga agaacttggc
     5041 gcttttatcg attgctatga atctgggaga agaaatgtga cgcgtcatgc gaatattttc
     5101 gctgttttat tcgattttgc taacaaagac caacagcaat cgatcttaaa gaatgtctta
     5161 ttgaatgaca ctatcacaca gattactact ccatatttca aattctatga acaagatgct
     5221 ttatgcaaac tcggacagac gaatatcgtc taccaaacga ttcttgatta ttggggaggg
     5281 atgttatctc atgatgcggt aactttctgg gaagaatacg accctactca aacaggaaat
     5341 gaaaagtaca gtatgtatgg agatccttat ggaaaaagct tatgccatgc atggggagca
     5401 agcccaatct atcttttagg acgctatttt atcggtttgt atccaacaaa gccaggttat
     5461 gaagaattta tgatacaacc taatctagat tcatttgaaa cactgaattg tacgctacct
     5521 atcaaagatg gaaagatttc gcttgaaaaa acaaaagata agatcgtgat tacttctgat
     5581 agaacaggcg gaacagtgaa aatgaatggt aaaagttatc ctcttctagc aaaacagcca
     5641 cttgtcttaa caagctattc aaaaataaat gcataaaaca aaaaactgct tgcgacatat
     5701 cagaagactt taaatcttct tctgatattg tccaagcaat ttttattttg aagtttgctt
     5761 aattctgttc tttagaaaca atgtttgttc tttttccggc aaaaagaaag ctagataata
     5821 cgacaagtaa aaagaaagcg atgattccaa ctgtcaaggc tatttgaccg tattctccta
     5881 gtttcccaag tacaagtcct ggtactagat aatcagtatc ggcaaatgta gaagaagcga
     5941 ttttaagatc tcctaatact ggaaggataa ataatggcag ccaactaatc aataagctat
     6001 tgaaagcaga acctaatacc gcccctcttc taccgccagt cgagttgccg aagacaccag
     6061 aagcagctcc gcagaagaaa tgtcctacta ccccaggaat gataactgta gtttgcaagc
     6121 ctatcatagc aaacatggat agtgttccta caaagaagct aacaaaaaag ccaattaata
     6181 cagcattagg tgcatatgga aaaacgatag gaacatctaa tgctggttta gaatcgggta
     6241 cgagtttttt agcaatccct tggaatgctg gaacgatttc tgccaacacc attcgaaccc
     6301 cttgaaggac gataacaaac ccagctgtga atgttccagc ttggatcagt gcaaagatta
     6361 cagcgttgtc tccattgctt agttctcttt caacaaatcc aggaccagct aacaaagcaa
     6421 gtgcgacata tacgatcgac atcaagagca tgatcgatac agtagaatct cgcaaaaagc
     6481 tgaaactttt aggaatcttt atgtcctctg tagaacggtc tttgtttcca aaaaactttc
     6541 cgatccatcc actagaagca taaccgatat ttccggtatg ccctaacgca acttgattgt
     6601 ttccagtgat gttcttcata aacggttgac aaagagcagg cgtaatagtt aatagtgttc
     6661 cttcgaagac cccgcctaat aagatcatcc acaaatttgc agtaaacccc gcgcttacta
     6721 aaatgactgc tgttagacaa gaaacataaa gcattgcttg acctgtaaga aaaatgaatt
     6781 tatatcttgt gaatctagca agtaaaatat tcacgatcat ccctactagc atgatcaaag
     6841 cagtaggtgt accgtattgt tgcaaagcaa tcgccactac tgcttcattg ctaggaacta
     6901 ctccttgagt atgcagagct gtttggaaca tcgaagcaaa aggggttagt gaattactga
     6961 ttaaaccagc accgccgatc agtactagga atccgacaaa tgttttgata gttccttgga
     7021 tcacttctga aaatttcttc ttctgaagaa cgagaccaag cagtgcaatc aaagaaacga
     7081 ggatggaggg ctgactgacg attgacacaa acaaattcaa caatttatcc attgatagtt
     7141 cctcccttga atcattttta ttcttttgac aagatcttcg ttactttttc ttttacttct
     7201 tcgctgtcaa tgatcgattg caaaggtacg agcttttcat caggtataga agttagcgta
     7261 tctttcaaag aatgctcaat gaagaaataa tcagccatat cgctagatac acttccaaca
     7321 tccgtatgac ttacttcaaa ctcgtccaca tctgctccaa gatctgcaag tgcttgtttg
     7381 atgttcatct ctaccataaa acttgttcct aatccacttt gacatactgc aaaaattttc
     7441 atatcattcg tctccttttc ttatgatcgc taatatttct tcttttgttg atgcgtgtaa
     7501 taaatcttga agattttgtt tattagaaag tagctttgtt aaatttgcca aagcccgaag
     7561 atgtgcctca ttatcgatag cagctaaaca gatgaacaaa ctaatgggat gggctggatt
     7621 atcaagcaga tccacaggtt gttgaagttt cagcaaagac atccctactt cgtttacgcc
     7681 atcttctgga cgagcatgag gtaatgcgat gtgatcgcca atatggataa acgcaccata
     7741 ctgctccacg cgctcgatca tagctttgat ataactttct tctattttat tttctgataa
     7801 tagcggctgt gcggcaaatg tgattgcttc ttgccagttt tttggttgat ccgataattg
     7861 gatcatttct tctgttaata attcagatag cataggacgt tgatcctcct tcttttctaa
     7921 aagtttgttc attttacgat ttaatacttg atagagcttt tcttcgtcta cgccttcttt
     7981 taattcgata taaggcagta gcgccgacaa caattcttgg gcagaaggca ttgaaaatcc
     8041 tggtatcagc caatctcttt gtacttgatt gatcagctga tttttttcca agtcagtcat
     8101 gattggatgc agaacataga gagacttttt cttatcagta agtgtgagag gtacagtaga
     8161 aaaaataata tcgtaagaag tttcgtcaac ctcgtgtaag cggtcagctg aattagtctc
     8221 tgtaaaaaag atcatcggga ataattgctg aagttcactt tttaagatca atgaagagct
     8281 aatgccactt ggacagacga tcacggctct tatttttcta tttctttctt ctgcgtccgc
     8341 ttttctgatc tctccgccaa atagtatagt gaaaaaacca atctcttctt cagggatgct
     8401 cttccctatt cgtctttcta acggaagtaa tgcttttctt gtcatttcgt agatggaagc
     8461 atattgatgc ttaatttgat cgatcatcac attaggtaaa taaaaagaat aggaaatacg
     8521 aaaataggca gggaccaagt gataaaagac attcatcaat aattcacgaa acgaagcaaa
     8581 ttctacggcc atcaggaatt ccatgcgatg gatgacttct gaagaacatt ccagcaaaaa
     8641 atcaagtgca ggctcctgga catctccttc aacgatcgat gctaagcaaa gagagaaaaa
     8701 tataatctcc gaattttgat gttcggaata gccaaggcca gtcaatactt gtcgactaat
     8761 gtcagtgact gcaagagaag ccaacagttc agcatctttt accagttcca tggatgtttt
     8821 tccaattcga atggttgtca aactcaaata ataagctaat tcatccattc gatttggtgc
     8881 gaatcgaaga tctgatagtg aaatcgtttt atctagcaaa tctctaactt tggcgtaata
     8941 atcaatggaa agggttgcgg ttaaatacgt gagcccaaat cttccagcaa gtgactgcat
     9001 caaacgagca gtgcgatttt ttgcttctct tcttaatatt gcttctgacc ctagcagcct
     9061 aaaaccagtt ttcctagtat acgacagctg acaatcttcc acttctaatt catttcttat
     9121 ctttttgata tctgacagga ctgtcccttt agaaacctga agaaaatctt gaaaatgaaa
     9181 aacagaaaca gacgttgcag tcgaataaac catcaaataa agaagatctc ttcgctcttg
     9241 ttcggtatac acagcttcaa atcgagtaat atccaaaaat ttttctgccc agtcgattgc
     9301 tcggaatttc tttatacgga tacgggtatc atccacatat tcggcaaaag gagttaattg
     9361 tttgatcgcc tcgcttgtat ttacttcgat gatctctgct gctttttcta gactgatttc
     9421 tcttggtgtt ttcaggagat aactaatttt gtagttcaca gcgctgttca cctcctactt
     9481 atattctagt atggtagcgc ttttaaatcg aggggtgttt ggtacaactt acagttggat
     9541 tttttttacg actgtaccga acgatttcta tcgaatggat acagaaaaaa agcaggtgac
     9601 caaatgtctc ctgcttttat gaattgattt cgtccgatca atgatgatca tgtttatttt
     9661 ttgaggtcag ttcttcaaat ttttctttga catcttcaac cgctttttcg atatcttttt
     9721 caaagtgatt gggctcatta ggctttgttt cctcttctac agaatttgaa ccagataaag
     9781 ctgtttcttt attttctgtt tcaccagagt ttgtgccagc taatgattct tctttgtctt
     9841 ctgtttcacc agaattagtt cctgctaaag ccacttcttc ttctgtttta ggggccattg
     9901 aacctcttaa tcgtttgtgt ttttcaccgt cataatttgt catgttggtt cctcctagta
     9961 gttctatact ttttcatcgt acaataagac agtttatgcg tcaaaaaaca aacccgattc
    10021 ttacaaatat gtcatatttt tccttctgat tcttgaatgc ttttgattcc ttcttccaaa
    10081 attttcattt gtaagattgt ttcttcatct ttgatgactt tttctgcgcc attaactaat
    10141 gtctcgtaaa tcccttcgta gacacggctg taatcaccaa cctcggaaat tactttttct
    10201 tcatgataac tcccttgttc atctatatag gtcaatacac cataatgttc gggcaaatcg
    10261 ataccaaagt cttcatgatc aggcatgtaa aacattttca gatgttcttc ttgtcgatct
    10321 tttgtttgtt tcacgaacat cccttttttt ccgtaaacga cgaaacttgg acgttctttg
    10381 atgcggaaat aactggattt tatcgaaatt ttcatatttc catagaaaaa atccagatcg
    10441 aagtaatcat tcattcgtcc tttccctaaa agttgacgta catcatagct gatatcatct
    10501 ggttcgccga aataagaaag aacttgatct actgtatgac aagcatgtcc atataaatag
    10561 ctgttcgcag tagaaaattc atgcgtattt tctggtactt ccggtctgaa ataatcataa
    10621 tgcatttcta cttctaaaat atcccctaat tttccgcttt cgattacttt ttggactgtc
    10681 aagaagtcag aatcgaaccg tctgttttgg taacattgga taaatagacc tttttctttt
    10741 gctaatgcaa ataactcttc tgcttccttt gacgtttctg caaaaggttt ctctactagt
    10801 acattcttac catgttcgag tgccattttt ccatattcat aatgaaattg actaggtgta
    10861 gtgatgacaa ctaattggat ctcaggatca tcccaaagat cagacagctg atcagtatat
    10921 tcgatgtctt cgaatgtttt ccacactggt tcagatgggg aaaaaatttt tttgatattg
    10981 attttgttcg taagttttct tgaaaaaggc aaatgatagc gatttgtact ctttccattg
    11041 ccaagataag cgattgtaag catgagtggt gcctcctttt attgatgttt tcagtatatc
    11101 ctagaaaagc gcagaaagta tttataatag ctattctggt aaaaaagttc agaaaaacac
    11161 ttgttatcat tcggtttggt gaaattaatg ttcaaagtaa ggataaaaat caaaaagata
    11221 gtagcggaac caagtgttta tcagtaagat agaatttgga ggtcagatca tgcttattga
    11281 agaaaaacta acaaaacaag agttgtttac cacgacagag aaacggattg tcgattacat
    11341 ccgtaggaat atcgaagctg cagtctacat gacgattgaa gaattagcaa aagctacgta
    11401 tacttcccat tcagctatca ttcgtttatg caaaaaaatg ggattcagcg gatttaaaga
    11461 attccgtttc gagctggggc gggaagttca tcaattgatt gctcagttca atcaaacgat
    11521 tgatcctaat tttccttttt caagtgaaga tagcactcag caaattgcaa agaaaatggc
    11581 ggatttatcg atccagtcaa taaaaaaagc acaattgcag attgaacatg aagatttaga
    11641 tcaaatcggt aaagtattga acaaggcaca gcgaatcttt ctttttgcaa aaggtgattc
    11701 tcaaatcacg gcaaggaaat tccagaataa aatggtcaag ttgaataagt ttttgatcat
    11761 ggctgaagaa tacagtgatt cttcttggaa tgcagccaat ttgactagcg aggattgcgc
    11821 catttttatt agctacagcg gtcgcatcca tcattatgaa cgaataatga cctatttgaa
    11881 gcatgtagag gcccctacct tgctgattac cggaaatcag cattcagaaa tggccaaaca
    11941 ggctgatatg tgtcttgtta tatcgcagga ggaatatgat tttgctaaag tagcgacttt
    12001 ctcctctcaa attgccttcg attacgtatt aaatacgtta ttctcagtga tatattctca
    12061 aaattttgaa gagaatatcc gcaacttgaa aaacaaacaa gaattgatgc aaaaaggcct
    12121 tcttaaagaa tatcggaaaa cttaagaaaa gatcctcatt tagtaataag aaagatagtg
    12181 tttgataggc tctctttgat atcatcataa aaacaggctg aagttttctt tttcaaacct
    12241 cagcctgttt gtttacggaa cgattcgaat agatatatta tagaaatgag gaatagctaa
    12301 cttctgtttc ttattttgaa cgattgacga aaaagatata taagaaggag gaaaatcagt
    12361 atacatgcag ctaacaatcc atacaggaaa aatcgtttgt tctcggatac tttctgtact
    12421 tctttttgaa cttcttttgc atgataagga acccggtgcc ctctgacaag taagcgatga
    12481 ctgttgacca tataaggtgt acaagttagg agtgtcacga aatcctgccc tttttcgatt
    12541 ctcagatctt ttgtatcagt cggttctacc gtcttgatct gatcgacttg ataagcgagt
    12601 gtccgtccat tgatttcgat atagaaagaa tcacctaaag tcagtttcgg taagtctgtg
    12661 aacaactttg cttgaggcag tcctcgatgg ctggaaataa cggcatgtgt attttctccc
    12721 cccgtaggat aagacgttcc ttccaataat gaggcacctt tttctagcag cacagtattc
    12781 gtttcatcaa aaattggcaa atggacattg atctcaggga tcgtcaaaat accgatcgta
    12841 tgtttctcaa aataggttct atcctttttc gcaggttctt ttttcttagt aaagggatct
    12901 gcacctggat ttccaccttc ttttgctaat tgctggtttt tctttgtcat gttttcttgg
    12961 attttagcca tgacttcttc attttctttg accgcttgtt gctgataatg agagatgatc
    13021 tgctgatcca gataattatt cagcgcgtcg ctaacaaatg gataagctag tatccctatt
    13081 cctgagagaa gcaagaaaag catcagcaga tctagaagtt tccttttctt tggtttcatt
    13141 tgtgttctcc ttgtgatgac tgtttgataa taaaagaaaa aggagcattt gcgtaatccg
    13201 ctgctccttt ttccaattct tgcaaaaaga ctaaatctga ctgtgcttgc gtctagcaaa
    13261 gtacagtcca gcaatcagta gaaggactac tcctgcaccg atatacacat agattccctt
    13321 accgcctgtt gaaggaagtg tacctttgtg tttatttggt attttttcag gagaaatcaa
    13381 ctgtcctgct gttacataag attgttcatc gatagtaaat gctacacggt ttgttaatgg
    13441 aacatatttt tctggcgctt tcgtttcttc cagatagtac gtgccatatt ttagacctgt
    13501 cacatcgatt aaaccgttac ttgtggttgt aaaaaccgtt gctgattctt tcgccgatac
    13561 ccagctgacg gcttttgtgg atgggtcgat cgataaatat ttcgctgtgt cactatcttg
    13621 atcacgaacg acgaattctg ctccagcaag tgtttggtct gatgtaacgt caccatctac
    13681 tttaacaaat cgtttgcccc cagtaacgac atcgactgac ggtggtgttt gatcatttgt
    13741 atgcccgtta tcgacatttg cttggttaga aaatcctttg gttggatctg ctttttcgtt
    13801 caaatgcata tagtaaacga atttcaatgt accgccagga gttaatgaag gaatataatt
    13861 cggatcaact gaaaccgtga atccgtctgt ttgctcagtg acagaataat ttactgggtc
    13921 gatttcttta tttccatcat ataaggcata agcatacgtt cctgaagaat cattatcaaa
    13981 tgttaaagca gcgtcatgag tatcgataag tttgaatgtt gtgtacttgt tttgcgttcc
    14041 ttctttatca gcgataccta atgggatatt gacagaaatc tcatattgaa ttttttcacc
    14101 gattgcgaca tcttttccat tcaattgagg tgttgtttta tcaactttag acgtatcatt
    14161 tttgatggtc ttttctactg gtgtttggct atttgccagg atctcaaaag gcgtgattgt
    14221 ttgcttttca atcatttccg cattatcagg agcttttact tcttctaaat tatattttcc
    14281 aacttctaaa tgattaacga tcaactggcc tttttcaata gatgcctcgg caaagtcatt
    14341 gttgccgatg tcataagaat gaccagtaat gaaatgtttg gctttggttt gatcagttgt
    14401 ccaagtgtac aatccatctg tgacactttg gatgtatttt ttgacgcttg gtgttccttc
    14461 ttctttagaa ataataaatt ctgctccatt tagtgcttcg ttttcggcag taccgatttt
    14521 tgtaactttc aacgttccat cattaccgac tgtattttta gggtagagat ggatagtatc
    14581 tagttcttct gtcccgtatt tataagagcc atctgcttgt ttgatcatct catatacagg
    14641 gaaagctaaa accatgtttg cggcagctga cactccgtct tttggttctt ctttgatcgt
    14701 gtagactgca tctttcccat tttgtttttt aggtaaagat aaagtgacat ttccatcagc
    14761 atctgtcgtt cctgaagcaa ctggtgtacc aggagtcaaa gactggactg cttgttttgc
    14821 tgcatccacg gacgctcctt tatctcgttg cgcataaaat tcttgagtga cgttataaac
    14881 tgaaaatgaa atatcggcta atccttggta ttgatcgaat tcgctcattt ctttcccgct
    14941 gttttggatt aaaggatcgg gtaaatcagt cattttcttt ttatgaagga tgacttgagc
    15001 tgctgtctcc tctgcaaaca ctttttttgc gccgaagctg tttgtgagta atggtaaaat
    15061 aaggaaaagg actcctaaca taacgtttat ttttttatga tttttcattt tttcactcct
    15121 gttctttttt tgataaacaa ccagattgca aagcttgcga ataccatacc aacaacgcct
    15181 aaaagtgtat ttttcgtttc gtttgttttt ggaagaaatg gacggctatt ttctttttta
    15241 ttgactactt tcaatatact gtccgcctct ttatcctcag aaagaaaagt tgaaatggta
    15301 aacggaattt ctgtttcact taaaatataa ccagaaggtg cttcgatctc ttttaatcga
    15361 taacttcctg ttttcaaccc ggaaattgaa aaagcgccat ttttatcgga aatcaggtga
    15421 agcgcatctg attcgttctt tgtccacttg tatccgttgg ctgtttgctg gaggtaattt
    15481 cctgctttgt ttttaataag gaatactgcg ccagctaatc gtttatctgg tttatttgtc
    15541 tcgattttga caaattgctt actccctgta tatacagaga ctttctttgt actgacacca
    15601 aaaccaaaat ccagtgttcc gttgttgttg atttccttgt tcgcctgtgc tgtactgctt
    15661 agctgcatct gataagaaat ggtcagtttt tttccagcat atttttccaa cgaagggatc
    15721 gaaaataaaa catcaaatcc gtgaggtttc ttgtgtatga caaagccttc tgtcagcttt
    15781 tctccattcg atgaaatcgt taaactatta ggtaaaaacg ttaatgcttc atccgcacta
    15841 tctgacaatt cgaacttttg atagtcaagg atatttacag gaattgtcgt atgcaaggaa
    15901 taagtgattt tttcaccaat cgtaaaatca tttctaggct cttctaatac cttctcaaaa
    15961 ggtggatcag ggtagtcgtt ttcttcattt ttaggataca aatggatagt tgaaagtttt
    16021 tgattgtttt gtccatgtac aggaagaaca actaccatat tctctgcctt ttctttgacg
    16081 acttctggta ctttggattc aatgaaaaga tacgctttat ctcttttttc ttgatcttta
    16141 gcggccagag aaaaagaagc gataccatct tcgttgttaa gagttgtagt tgttgcttct
    16201 gcggtaaaca taccggaaga cgcaccgttt tttgcgatct ctgcttgtgc ttcttctacc
    16261 gttttgccct tttcccgtag atggtaaaaa gaatctgtga catcataaac ttggaatgtg
    16321 acaccattta atcctcgata cgtttgtaat aaagcttttt cttgtccgtc atttggatga
    16381 tttttcggca gttgcccgtt tgggaaaagc aatttgtgta aagtaatctg aaccatttct
    16441 gtttctgttt ctgttgctac ctgagtaaaa gctggtttaa atagtaacaa gaagagacac
    16501 atactaagcc aaccaagttt tttcatattt agctgccccc tctttctttt ttcaaaaaaa
    16561 gataccaaat agaaaacgca caaccaatca tccctactag atagattcct aaacggccaa
    16621 ttcctcccgt ttcaggtaat ggtacttttg cctgattcgt gatgtctaaa gaaatctggt
    16681 tgtttttggc tcctggtgac agaacagatt catgatcttg tccatccact tgaattgacc
    16741 catcttcgtg tataactata gtaactggct cttttagacc ttggtatcct tctggtgtaa
    16801 aagtttcggt cagcgtataa gttccaggtt ttaaattttc gaatagaaag gtatctgttt
    16861 cttgtccatc ttttggcgat tctaagtcca tttctggtcc ctgcagtctg aattttgctc
    16921 cttttaatgt ctgtccgttg tcttcttttt tgtgtaccgt tagatcaaac gcttttagtc
    16981 gattttgatg agtgagcgtc catacattat ttgtcatctc ggtatttttt cccgtgtaaa
    17041 tgatttttcc atatttatcg atttggaatt cataatttcc cggcgaagta tcatatccgg
    17101 caggaccagc tgtttcaacg actcgatatt taccaggtgt gagtgaatca aaactggcaa
    17161 gacctttttc attcgttgtt tggctgtcaa ttggctgata agtaccattt gcttcttttt
    17221 tctgtaggga aaatgctgct cctttaagat ttatctcttt gtccgtccct tgcatcgcat
    17281 acttacgtac tgctacagga acttcaacaa aaggattttc aatagtcaac tggatcgtat
    17341 catcggaagt agtgactgtt tttccatcaa tggttaccgt accatcagaa gcgatcttga
    17401 tttcccaagt agtctttttg cttaatccat gcccttctgg agcttttgtt tctgtcagcg
    17461 tataggtcat ttctttttgc aatttgacat tttctggaag agaataggtt ccgtcgccat
    17521 gatctgttag taaagtatca atagaatctc ctgttaattt gaaaacagcg ccaataagat
    17581 ccttttcacc tgtagaggaa tttttcgtta ttttcaagtt taacggtgtg aattgtttag
    17641 tatttttcca tgtcattgca tctatttgtt gagaatcgta tcctggtaca ggtaattctt
    17701 tgattgtttg gtaactgaat gcttgacctt gattattgta ttgaggtagt gataatatct
    17761 cttgataact ttctccgcta tttgcagata atttgtcaat gtctgcacgt tcccacgtat
    17821 ttgttgtatc tttagctggt ttaatgattc gaatatatcc gtttttccaa gctgcagcat
    17881 ttgtcgtatg ttcccgttga atctcaaaag taacttgatc tggacgatca gctagattgt
    17941 tgtcaaattc ttcccataac tttttgatgt gaagactgac tccgggagct ttagcagatg
    18001 gtataccgaa ttcagctaat tcattggtat caatgtttgg ctggaaagtt gtcctgccgt
    18061 tcatttgata ccagaaattt ggatggaagt cctcattttc tgtttggatt ctcacttggt
    18121 aatggatttg gatttcttgg tcttttccta aatagatctg attgctcttg atggtatttc
    18181 cttctatgga aatagatgga gtgaccgttg taggacttgt ccccacactc ttgactgaaa
    18241 gtgtaccagg ctgataaatg aatggttctg cgattggatc atttatttgt ccattgctta
    18301 cagttgctga gatctgtaca gcttttttgg ctaggtattc agagatatct gttgcatgat
    18361 cagctgattc atagtaaaga tcgccttttt catctgatga aaccatttgt cgcatacgag
    18421 actctacttc tgcttttgag agaccagctg ccggatcgct ttgaagttgg atgccaagac
    18481 catgtatttc gattcctcgt tctttgagtg ccatcgcttc tccgatggtt gcgataaacg
    18541 tactgtcgat tcttctggat agattgtttt ggtcaggtgc atcatagatt cttgagatta
    18601 gagaagtatt tcccggccga tcttgcgtat tagaaaactg agttccgtaa taattgctgc
    18661 ttgattgtgc gtgtacccgc tgtactttat aggaaaatgt tggtacacca tccgtcagca
    18721 aaacgatcac ttttttatgt ccatttggaa cggatagcat gcttcctgca tctcttagtg
    18781 ctttttgtgt aaaagtacca ccatttgtcc gtgaaggtgt aatggatttt acttgatttt
    18841 tcactgaatc aaatgaaccc atctgtactg caccgttact gtagctatat ccttcgcttg
    18901 agtagccgac atatcccata ttgattttgt ctgtgatacc gctatctgct aaagtatcga
    18961 caaaacgatc gacaccaatc tttacttcac cgatccgatt attgtcgttc atacttcctg
    19021 accagtctac gaccaatacg agatcaagag gcgtgatatc tttttgtaca tttccacgag
    19081 cattcaaata aacatcaaac aatccgggtg tacttgtttc ctttgcatac tttcgtatcg
    19141 catagtctgc ttgattaccg gttcctccat attcgatata cgaatgggtc cgatcattag
    19201 gatctccatt ccaagaattt ataccatccc attgatttgt tccgttttta ttgccttgat
    19261 gatcaagaac atttgtattt cctgtaggtt gccaactggc tttaggataa gtgccctgat
    19321 catctgttgt atattctgta ggaatcgttt gattagatgg cacactcaca gctggcaagg
    19381 ataatgtagg caatgtaaat gggctgacag aattttcgtt ttcttttgat gattcttctt
    19441 ctatttcgtc tggctttggt actgacacat ctgtatcttt cttattttct gtctcatcaa
    19501 taatgtcata ttctttatta tcgacgatca gcttgtttgc ctggctgtgg taaagtgctg
    19561 gatcgattgg aaaactcaga tcgatagttt gtttagtgtt tgatgagatt tccaacgtaa
    19621 ttttcccgct atttacctga taagcatagc catctccttc ttttctttcc acatcactta
    19681 agtaattttc gactagacca atttcttttt ctatcttttc agcactggtg ttattcgcat
    19741 ttagcttgat gttcagtgct ttttttccag actgatccga aatgacttca gctgaaattg
    19801 tttctaaaac tgttggatca tctgtagtgt ctgctattgc agataatggc acaaagtttg
    19861 ataaactcaa tattatcagc atgaaaataa ctttcagttt cttccctgtg gtcgtcattt
    19921 ttcccctcct ttttcttttt ttctgttttg acgtgaatag tgaaaattat taaaataaac
    19981 aggcgttaca taattttatt tattttaata tgataattat tatacgaagg gcgctaaagg
    20041 gaatcacacc aattttcata ccaattggtt tcatttatga agttgattcc ttcgattaat
    20101 gagcgtttca ttgaaagaaa agggttgagg gagaaaaaca tatgatcagg ttgttggaat
    20161 taaactatag aaagatggaa aaaatcattc gaattctgtc catttctgac aagtggatga
    20221 ctaaaaaaga acttgccaaa cgaattggta gttcagaatc tacatttgta aggtatatcg
    20281 aagagatcaa aatccgctgg ggaacggatg taacgattca atcttcacaa aaattggggt
    20341 atcgtcttga acatttgaat gtaccagctt atttaaatgt tctgatggaa atgtcgcaaa
    20401 gttctacaaa cagtcgttta ttaaatgaga ttattgtcaa tccgggtaaa acgattgagt
    20461 attattgtga aaaaatttcc atcagccggt cttcttttac acgtaagttg aaacaatgca
    20521 atcaaatttt agaaagctat ttattaaaag tgatcgttga ccaaggtttt cagttaacta
    20581 gccttaaaag tgagctccag ttgcgtatct ttgttacctt tttcttttta agttactacg
    20641 gaagacgcac gttgccattt ccaatcgaaa aaaagaagat caaagaaatt atggtcaaga
    20701 ataattgtca gatgaatttg tttcaggaag aaagcccata tgagcaatct ttctttatta
    20761 tgtattttgt tgtgcatctc atgagagaat cccaaggaac tccatttgaa tggaaagctg
    20821 gagactctta tgtacagttg ataaatatcg ataaaaaaga cttcttaatc ttgaaaaatc
    20881 tcttaggaaa attgaagtac agcagctata taaaagtagt gaactatttt gtcaatacga
    20941 ttttttcaga attttcggag aaagaaaaaa atgaaatcag tgagcagata cgaaaaaata
    21001 tgtcctactg ttcgttttca tccgctgatt gcaaagaaaa aaacgaagaa tatgttgttc
    21061 aattattaac gcaaatttat tttttctccc gtattttccc atacgatacg actcatttga
    21121 cgatccgtgc aacttacttt gcacagcaga tgcaacaccg ccagatacgt ctatatgctg
    21181 gatttcgtgc agaacttcaa ttttattcca ctctactgaa tcagaatctg atttattatt
    21241 tatctagcta tatcttttgg atgcttatcg gtaatcctga aattcaccat tatacttctg
    21301 ataaaaaaat actgattatc agcgacttaa gtcttcgaca tagtcaatat attgaagaat
    21361 atatcagtga tattcttgct gtgcataaaa ttcactctga gacaactgct attactgaag
    21421 atcagctgtc gaaatacaat cttctcgagt atgatctgat cgttacgaat caacccattt
    21481 tgaatgccca tgttcctcat atattgattg atgatagtgt gtcattcgca aatgaagaag
    21541 aactcatccg cttattcgag ttatgaataa tcaaaaaaca gctatgtata aaccaccctg
    21601 ataaaaattt caggacaaat acacatagct gtttcttttt attgtattcc ttcagcaatc
    21661 caacgagatt tatagcgaaa gtcttttaac aactcttctt ttgtccaatt atttgcaatg
    21721 agatccgtca aagtgttcat tacgagggtc atggaaaagt ataggaaact aactgcttct
    21781 tccgacgatt gaatggagaa atgattgatt cttaataatt ccagccattt ttcgttcatt
    21841 ggagaatcag ccgatagttc tctacgtttg gttgtctgct gatcatttcg ctgggttaac
    21901 aagtataacc tttgccaata gatactttcg tgatctaagt cgcagcacca ctctaaatat
    21961 ttttcgatcc ccaaaaagaa atgttgtttg ttttcgctaa tgaattttaa gatatcttga
    22021 tggactatgt gagaactgct tttgatcgta tacaaataag catcttccaa atcttgaaaa
    22081 tatttataaa aagcaccgcg cgacatcccc atcttgtcaa cgatttctga gactttgact
    22141 tggctgatgt gctgtgagca aaatatctcc agtaataggt catcgattct ctgtttcttt
    22201 gcgttcgata aattgaaaaa agtttctttt ggcatccaca tctctccttt atctctgatt
    22261 atacgtggat agcccttcat tgtcatgaag gattcattcc ttctttttct cttcttctgt
    22321 caagtaccca tcttccattc gataaacgcg atcactccat tgaatcatac ggacatcatg
    22381 agtaaccata atagtcgctt tttgtttctc atgagcttct ttaactagta atttgacgac
    22441 ttcatatgca tgatctgtat ccaaactagc tgttggttcg tctgctaaga tcaagcttgg
    22501 ctcattatat aaagcgcgag caattgccac tctctgtctt tctccaccag aaaggtcttt
    22561 aggataacta tttttaagtg actggatatc taaagattgc agcaaggaat cgatttttgt
    22621 tgaatcttct ttttttgaag taacttggtc aactagttca aattgttcct ttaccgttaa
    22681 aaaaggaatc aaattagagc tttggagaat aaatcctatt tctttaaagc gtaaatctgc
    22741 tcgttttttt tctggaagct cagttagtga gtgaccgttg atcactattt ctccggaagt
    22801 cggtgtttgc aatcctcctg aaatggtaag gaaagtactt ttacctgaac cagaaggacc
    22861 aatgatgctg acgaattctc cttcctttac ataaaaatca attgctttca aagctgagac
    22921 ctttgtatga ccagaaccaa atgttttggt aacttttttc atcgttaata tttttttcat
    22981 ttttattaac ctcctattgc tgtaattggg tctactttgg ttatcgtacg tatcgaaaac
    23041 aatccgccta gcattgcgac aatgatcaaa atcccactat atagcaacca ttgtgaccaa
    23101 aaaacagcaa aaggcatcgc gcttggtaaa atcagactag tcaaataagc aaacaaaaga
    23161 gcaagcagaa cgcctaccac cccaacaata aaggactgtg ctactaaaga tttagcgatg
    23221 aagaaatttt tgatcccttg tgctttcatt actccaaaaa tagcagtctt ctgaagtgtc
    23281 atcacgtaca tgaaaatacc gaccacggca gcaaccacta agaacaaaaa gtatatcatc
    23341 gcatttaagg tcatattttg ggcagaatag ccaggaatac tttcaatgaa tgtcccaata
    23401 gttaataact gtagaccctt cgatgctttt tctttcgaaa ttttagctga atcctttatt
    23461 acgatcccat tgatcggctg ttcttcttca gaagcaaacg gctgttgtcc atacttcaaa
    23521 gcagtccacg tatctaggga cgcatagatg acgggagaaa ctgtgtaata agtttcagga
    23581 aagataccga caatcgtcaa aggatcgtcg taactgccaa ttttgatcgt atctccaatt
    23641 ttatagcctg aatcagccag attttgagag atgatgattt cattctttgt tttaaattca
    23701 tgccctttcg tgagttttgg taataaaaat gcttctttcg ttgtgccgaa aactgtaaca
    23761 ttttctttgt tttttccttt gattgctccg ctgtacaatc cgattggtgc tttctctcct
    23821 ccttcaatgt atttcagatc tcctcttgtt aattgtgaag ctgcaaatac ttgatttgca
    23881 tcctccgaca aaacaatctc ttgtgcgtcc caatcatcga ttgctttttt aaactcttct
    23941 gaaagtccat tcgctagtcc tgacaacatg aatacgacat acgcaatcaa gaacataata
    24001 ccgacgatca agccatatcg taatttagaa tagcgaattt ctttgatagc tagaaacatt
    24061 tgtttttcct ccctatgata gattgatagt gacaaaatgt cacttgttga atagtgtaac
    24121 tctaaagtga caatttgtca cttgtgttgt ttttttctta tcaataaatt gtctaagaca
    24181 tctttcgata aaaccttaac atgagtcata aaaaatttat ttaagcctta tttatgcttt
    24241 ccatgataaa ctaaagtgac caaatcaatg aggtgggaaa atgattaaac tattagtagt
    24301 agaagacgat aaagtattat ccaataatat aaaagaaata ctcgctgcaa tcggcgagat
    24361 aacacaagtt tatgatggta gtgaaggact gttcgagttg gaaagtggag tttatgatct
    24421 tgcaatcttg gatttgatga tgccggaaat gaatggatat gaagtgttag caaaaatacg
    24481 gaaagaaaaa atacagactc cagtattgat tttgactgca aaagatagtt tggaagataa
    24541 gattgaagga tttgaacgag gtgcagatga ttatctaaca aaacctttct atcgagaaga
    24601 actgatcatg cgcgtgaaag cattattgaa acgctcgcta ggtctctttg atgaaaatgt
    24661 tctgaagtat aaggatatca gttgtgattt aaaaagcaat gaagtcttgt ataaagaaca
    24721 agttttgccc atacaaggaa aagagtttga attgctcgtt tattttttac aaaataaggg
    24781 aatcattttg acaaaagagc agatatttga ccggatctgg ggatttgatt ctgatacgac
    24841 gattacagtt attgaagttt atatgagcaa cttacgaaaa catctgcgaa gtactggatt
    24901 ggataaagaa atcaaaacct tacgtaatgt cggttatata ctgcaaaggg tgtgatgcaa
    24961 tgaatggaga tattacacga aagcaacgta gtcgcttttt tgcgacaaat gtagcagcat
    25021 ttgcttttat cttttttctt ttgggattca ttactttaca gatattaaac caatctgcat
    25081 acagagaaac agatctgtca ttagagaaaa taaattttga ttctcgaaca gtacaattag
    25141 agatacaaag atatcagcaa ggcgatccct ttttaaaccc gactcaaacg gaacaaaaca
    25201 gaacaaacat ggaacagcca ttaatggaac catcaaatga ccgttttaac actcaagtga
    25261 tcttgtggtc taaaaatggt gagatattga ataaagcagc tattggtggg cgtttcaacc
    25321 aaatcaaaga attaaaaatg gatacgaaaa atctgaatac catccaaaat attgaattaa
    25381 atgaagacag tggctcatct gccctctctt tccgttcgat tacgaaaaaa gcggagacga
    25441 atcaagatgg cgttgcctac atccaaattt tagaaaatac aaatcaaatc aagaattcat
    25501 tagcgacttt tcgcacgatt atgattttgt gtatgattgt tttttggatt ctctctattg
    25561 gtatcagtta ttacttgtct agtctaagca tgcgccctat tattctttct tggagaagac
    25621 aaaaagaatt tgttgagaat gcttctcatg aattgcgcac accgttaacg attattcaaa
    25681 atagtttgga acatcttttt accaagccta atcatactat tattgaagaa tccgaaagca
    25741 tcgctcaagc attgtcagag acgaggcgcc tcactggatt gacttcggat ttgctgacaa
    25801 tcgctcggaa tgattctgat cagcagctgc tttcaaagca aatgatcaat acacaagaat
    25861 atatcgaaca acttgttaaa ccatttcaag agatggccat catagatgga aaagagttta
    25921 ttctccataa cgatgcaaca ttagaagtac caattgatga aaaaaaaatc catcaagttt
    25981 tggttatttt gctggataat gcattaaaat atacgaatcc agaagataag atcattttgg
    26041 attcatctgt taaccataaa gaatggctga ttcacgtaaa gaatactggc ccttctatca
    26101 gtgaagaaga tcaagcaagg atttttgatc gattttatcg ggaagatcaa tctcgggcga
    26161 aagagactgg cggatacggg cttggcttgg caattgcaaa acaggtaatc gaacagcatc
    26221 atggacagat ttctgtatcc aattatcttc cacaaggagt cgattttaaa gtccaattgc
    26281 cgttgaagcc taaaaaataa tgcttatccc taaaaaaggg ctgtgacaaa aatcttgtca
    26341 cagccctttt ttgttgcgaa taaacggtgt tccagaagta gcttcttcgg aaataagccg
    26401 aaatttcttt aagctgacca cttctgtcac aacctcttta gcttacgctt acgatttttt
    26461 attgcggtct tcaatgtgta catcaccgct tgtgtcaata tccaattctt ctcggctaac
    26521 atcttctgtc actttttcaa catcttcatg ttcttcttta tgaatcccaa cttcttcacg
    26581 aataactgta tgtttgctta catctacttg ctcttctttg attgggatag taatcgtgtc
    26641 atcttccaat ttttcgtctg ttccctgtga agattgatct gttactggtt tgcgttcgat
    26701 gacgatttct tcacgtttga ccggtacttc taccgtttca gtatcgttga ccacatgttt
    26761 gtggatgtcg acttctccag ttgtcacatc atgtgtattt acatctaatt tttcttcttt
    26821 tagttgaatt gtatcatcat ctagatttgg tttgcgatcg atgtcttcag tcttgcttgt
    26881 acccattgta tcagtctcgc caggtacgtc catcggatca gttcctggtg tcatattcaa
    26941 tggatccgtt gtattttgaa agcctgtcgt gccacctacg tccattggat ctgttccagt
    27001 gccagtttct aatccagtcc ccattgtgct tgctgggcta acagtatctt gtgtatccat
    27061 tgtatcttct gttgtttctg gctgacgata gccttttact gtgatgacaa attttccatc
    27121 agaaatatct cctctatatt gatataaagg atcattttct ggtgtagccg tctcagaatc
    27181 ataggtatca aaagaaaaag tatcttttat tttttcccat aaagaacggt cttcttcacc
    27241 atccatccga ttttcatctg tttcaacatc tataccagac aatccgtcaa atcctagtct
    27301 agatgctgct tcatcagtag tataaataac gatatcatct cgttcatacc cttcgttacg
    27361 caaccgttca attactgata atgcttcttc cctcgtacta tagcttccga tgaccgttaa
    27421 atttttctct tccatgtaaa ttcctcctag caaatagatt tatgattggt atattgttac
    27481 ttataaattt attctatagg agacgattgt tttctacaaa tatttagatt ggaatttgat
    27541 taaaacaatt taattgaaat ttgaaaacat ttatgttaat gaaagtcata ttctaataaa
    27601 atgtcatttg tttctatatg aatttttatg aaaaatttca tataatttcc actcgttgtg
    27661 atggtttaat ttatccaatc catcaataag caaacaactt atataaaaaa ggattaattc
    27721 tcaatataat tgctcctacc atagaataaa tcttcatgta aagtaatgaa gtaccaacta
    27781 tttctaatac ttctttaaga attatcccaa caatatcgtt agacaaacca ttattgaata
    27841 aatggagagc caatcgattc tgaaaaaatg ttttctaatt tttcggaaat aaaagaaaga
    27901 gcctcctgcc attagaacga accaaatcca tttcattgct catgaagtaa ccacatagct
    27961 aaaaagagga taaatcaatt aaaagatcaa aagaatgact gcactaataa aataactaaa
    28021 aatgtatctt cttacttcat atcttttagc tagtacttag ttaaaaattt gcttcctaag
    28081 atcaagacaa actgtctatc ttcatttgat gaaatgcggt aaaatataga aaatgaacac
    28141 tattggaggg aatttgtaat ggacagcaaa actagaaaac aactgcaaga aaagttaaag
    28201 caacgtacac acttgctccc ttccgtcttt caacagtttt tagaagaaaa tcgttcttcc
    28261 ctttcattag gcagtcgcta tgaatacgca aaagattttc atctgtttac tgattatttg
    28321 agaaaagtat tttctgaaga agtggatgat cagctgatta tccatttaga aaaacaagat
    28381 tatcagaatt tcttagctaa aatctatcga catactcgtt cgttccaaac tacagcgaac
    28441 caagaaacgg agcaattgtt tgaaaatagc tattacggga tttcaaggaa gcaatattca
    28501 ttaaatcatt ttttacgatt tttgtatcaa aaaggactga ttgaagaaga gatttctctt
    28561 ttgggtacaa gtttaccgga aacaaccaaa gcagctccgc gatatatcga tgcagaactt
    28621 ttcaaagatt ttgagcattt gtttatcccg attgaaggct ttcaaacaag cagagaagct
    28681 agctttgaag
//
LOCUS       DADGHT010000028        28074 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.028, whole genome shotgun sequence.
ACCESSION   DADGHT010000028 DADGHT010000000
VERSION     DADGHT010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.028"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(81..662)
                     /locus_tag="JX887_001097"
     CDS             complement(81..662)
                     /locus_tag="JX887_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1257102.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(845..1471)
                     /locus_tag="JX887_001098"
     CDS             complement(845..1471)
                     /locus_tag="JX887_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAX1257103.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(1493..2824)
                     /locus_tag="JX887_001099"
     CDS             complement(1493..2824)
                     /locus_tag="JX887_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAX1257104.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(2979..3380)
                     /locus_tag="JX887_001100"
     CDS             complement(2979..3380)
                     /locus_tag="JX887_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAX1257105.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(3466..3672)
                     /locus_tag="JX887_001101"
     CDS             complement(3466..3672)
                     /locus_tag="JX887_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257106.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(3767..5269)
                     /locus_tag="JX887_001102"
     CDS             complement(3767..5269)
                     /locus_tag="JX887_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAX1257107.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(5287..5742)
                     /gene="argR"
                     /locus_tag="JX887_001103"
     CDS             complement(5287..5742)
                     /gene="argR"
                     /locus_tag="JX887_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAX1257108.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(5840..6457)
                     /locus_tag="JX887_001104"
     CDS             complement(5840..6457)
                     /locus_tag="JX887_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257109.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            6678..8051
                     /locus_tag="JX887_001105"
     CDS             6678..8051
                     /locus_tag="JX887_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAX1257110.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            8126..9238
                     /locus_tag="JX887_001106"
     CDS             8126..9238
                     /locus_tag="JX887_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAX1257111.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(9310..10947)
                     /locus_tag="JX887_001107"
     CDS             complement(9310..10947)
                     /locus_tag="JX887_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAX1257112.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(11115..11723)
                     /locus_tag="JX887_001108"
     CDS             complement(11115..11723)
                     /locus_tag="JX887_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAX1257113.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(12107..13258)
                     /gene="queG"
                     /locus_tag="JX887_001109"
     CDS             complement(12107..13258)
                     /gene="queG"
                     /locus_tag="JX887_001109"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAX1257114.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(13277..14029)
                     /locus_tag="JX887_001110"
     CDS             complement(13277..14029)
                     /locus_tag="JX887_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257115.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(14170..15120)
                     /locus_tag="JX887_001111"
     CDS             complement(14170..15120)
                     /locus_tag="JX887_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAX1257116.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(15121..15960)
                     /locus_tag="JX887_001112"
     CDS             complement(15121..15960)
                     /locus_tag="JX887_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAX1257117.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(15957..16703)
                     /locus_tag="JX887_001113"
     CDS             complement(15957..16703)
                     /locus_tag="JX887_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAX1257118.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            16941..18311
                     /locus_tag="JX887_001114"
     CDS             16941..18311
                     /locus_tag="JX887_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1257119.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(18366..19262)
                     /locus_tag="JX887_001115"
     CDS             complement(18366..19262)
                     /locus_tag="JX887_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAX1257120.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(19543..20220)
                     /locus_tag="JX887_001116"
     CDS             complement(19543..20220)
                     /locus_tag="JX887_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAX1257121.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(20311..21216)
                     /locus_tag="JX887_001117"
     CDS             complement(20311..21216)
                     /locus_tag="JX887_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAX1257122.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            21391..22815
                     /locus_tag="JX887_001118"
     CDS             21391..22815
                     /locus_tag="JX887_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1257123.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            22861..23892
                     /locus_tag="JX887_001119"
     CDS             22861..23892
                     /locus_tag="JX887_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAX1257124.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            23899..25086
                     /locus_tag="JX887_001120"
     CDS             23899..25086
                     /locus_tag="JX887_001120"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAX1257125.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            25242..26624
                     /locus_tag="JX887_001121"
     CDS             25242..26624
                     /locus_tag="JX887_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAX1257126.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            26751..26981
                     /locus_tag="JX887_001122"
     CDS             26751..26981
                     /locus_tag="JX887_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257127.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(27181..27849)
                     /locus_tag="JX887_001123"
     CDS             complement(27181..27849)
                     /locus_tag="JX887_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAX1257128.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT         7814 a         5745 c         5154 g         9361 t
ORIGIN      
        1 tcacaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa gctgaccact
       61 tctgtcacaa cctctaatta ttaaagaacc ttttgcgaag ttaacaatct ttctttgatc
      121 aattgaaaat tctgcctaag tagtgataga tcctgtgtga ctttcaacaa taagatactt
      181 ccctggattt cagcaatcaa cgctttggct tgacggtctg cttcttcatc ggacagtttt
      241 tcttcagaaa gtgccaggat attttgtttc gtatacttga cccattgatt gactaattct
      301 agtagcaaca gacggtattc ttcatccact gtactcaact caataatcaa attacctaca
      361 ggacagccat gataagtgat ctgtgtctca tgatcagcga aaatccagtc caacatttct
      421 tctaatgctt cttctggctg ttttccagca tttaagatgt cttcgaacaa ttctgtctgc
      481 catacgtcca tatgcgcatg gatcaccgct agacaaactt ctttttttga agaaaagtaa
      541 taataaaatt gaccttttcc tgtatcagaa gctgctagaa tatctcggat tgacgtttca
      601 tgatagcctt ttttataaat aagatctttg gtcgcttcca agatcttttc ctttgttttc
      661 aatgatattc tcctttttca tttctcatag tcctatatta tacagtaaat tcatcatttt
      721 ttcttcttaa tcgtttaaaa aagactgtgc caaattatct gacacagccc tcactataaa
      781 actgttctca tatagctaga tgttcattga ttcaagaact gcgaggacaa aagcaattcc
      841 tatcttatga tagttgctct aatacttcct ctgttgtcat cacttgatct gcaataaagc
      901 caaagttcgt caacgctgca tccattgctt cttggccagg agcaccaatt gcatctgtcg
      961 ctaccacaac attgaatcca ctctctacca attcacgcat atgggaatcg ctacacaagt
     1021 ttccgttcat tccaccaaga attactgtgt cgattccatt ttttctcaat tggagcgcca
     1081 aatcattgct ttctggtcca aagattttat gaggagagct gatgatcgta ttttcatcca
     1141 aataaggttt caattcttcg ataaaatcgg ctcctgaacc ttcttccact gattcatatt
     1201 gactttttct agcaaacatc tgctgctcaa gcatcatatg ttctcctgca ccgccaaatt
     1261 gccatttatg gtcatgtggg taaaaataat gaggagaaat aaagagtttg tatccttttt
     1321 cttttgcttg ttttaccatt tcaatcatat tttcgatcgt attgtatttt tctaagatat
     1381 cttttgtcaa accaaagcca ccgcctgctg gtttcaagaa ctcgacttgc gggtcagtga
     1441 gaactactgc tgtattttta ttattgaaca tggtggattc tccattcgtt atttatttta
     1501 atacatcatt tagagcttca ctcattgtcg gatgagaata gatttgatct ctcaataacg
     1561 tataaggaag ttttccattc atagctagcg aaatcaagtt gatgacttca tgagaatctt
     1621 ccgcatagat acttgcccct agaatcaagt cagtttcagg gtcgactaaa actttgaata
     1681 cacctttagg atcttctaat acttgtgctt tagggacacc gcttgtcata tacttgaata
     1741 atttgtaatt gacgccttgt gctttggctt gtttttctgt taaacctaca ttggataaag
     1801 tcggagtgat aaatacactg taaggcacag ctttccggtt attcgttgtt cgtttattct
     1861 cgcccttcaa ctgatccata atgattcgat aatcatctag agagatataa gtgaactgca
     1921 atccgccttt gacgtctcca atcgcccaaa tgttgtctgc atctgtacga aggtattcat
     1981 ccacagcgat tgctccgcga tctgttagtt taacatctgt attttctaat ccaagtgatg
     2041 ctgtacttgg ttttcttcca gttgcagcca aaacttttga cgcttggatt gttacttctt
     2101 ggccatcttc tgtaaaggtg acggcagctg ttgattcttg gtctgctact tgatctacag
     2161 atacacctag atggaattcg attcccgcat ttgtcatgtc ttctaaaatc atttgcgcga
     2221 tatcttcatc ttcacgtgga agaaattcag aatgggcatc aagaacgaca actttagatc
     2281 cgtattcatt gaacattgat gcaaattcca agccaatata tccagccccg atgatcacta
     2341 atttttccgg taattgttcc tgatccatcg cttgcgtaga atcaatcaag tagcgacttg
     2401 tattcaatcc tttgattggt aaaatgattg gttcagaacc agtattgatg aaaatccgtt
     2461 cgccttcaac aatcactttt tcaccattat tcgtcacttc gatttgatgg ttagaaagaa
     2521 aacgtgctgt accgtccatc actgtcccag ttgcctcatc gctgatcata tgataatttt
     2581 tggcgcgaag catgcccgtc aatttttctt tccgagcaac agcctctgta aagtcgattc
     2641 ctctttctcc attgaaaatc aatgatttag aaggaataca gccgatgttg atacatgttc
     2701 cgccatacat acgtgttgac ttttcaacga ctaaaaccga ttcacctttt gaagctaacg
     2761 ccttcgctaa agtcttaccg ccctttccaa aaccgatcac aatattttga tatttttcca
     2821 tcatttttcc ctcgcttctt ttttacctac cgattggtac aaaaatatga taaccgataa
     2881 ttgtctattc tccaaatcat ctgctttatt tgtcaaaaaa aaccagacaa aaagcggtcc
     2941 tttcacgttt ttagtctggt tcgatttcct ttattcttct aaacaatcgt tacttctaca
     3001 tcgatatttc ctctagttgc tttggagtaa gggcagaatt catgcgcatc ttctgcaatt
     3061 ttttgggctt cttcttcgct gatgccatcg atatgcactt ctaatactac accgatctga
     3121 tagccgccat catctaaatt ataaagagag acacgtgctt ttactgtgga ctctgctgtc
     3181 attcctgctt ctttgatcat atgttgtacc gccccattga aacaagaagc ataacctgct
     3241 gcaaataatt gttctggatt tgttccttct gcatggattc ctggaggagt gattttcata
     3301 tgcatcgagc catttggtgc ctcgacttct ccattgcgcc cgccatggtt gatcattgct
     3361 gtttcgtatg cttttttcat tgtactgctc ctttcgattg accatttgct acttggctat
     3421 aattatagtg tatgacaagt aaggcgcttt ctacaaaaat tctgcttatt cgaataccag
     3481 aatgccgtct tctactattt ttccaaaaaa caaaaaaata ctactcgtga acaacagcgt
     3541 catatttgtt ccaaaataaa tagcaatctt ttctacataa tcttttatat gattgatttt
     3601 aagatacata tataccagaa agttgacccc ataaaccaat actgttaaaa aaataaccat
     3661 attcgttacc attttttcct ccttttgctg gtctccctac cagcactcga tttaaccata
     3721 ccactttttt tgccgtccaa gcaactagcc tttcaaaaag actggtttat tctgctgtta
     3781 atgattcaag atcagaaaaa tgtccgaata attttgctaa ttttactaac gccaacttgt
     3841 tctttccgaa ttcatcattt tctatctgta atactagtaa cggctcatgt aagcttaaac
     3901 ggatcaaaaa ccagccgttt ccgtatggct cttctagatc atatcgaata ccttcttcat
     3961 tttccgggtc gaagttcatc cctttttctt cttccaacag tcgcttcatt tcttctaata
     4021 tcttgtttcc ttgttcgcgt ggttcatcgc tgaacaattt taatcggatt tcttgtactt
     4081 ctacgggctg tttcaactct ttgatttgtt catctaatgt gatacctttt ctttttaatt
     4141 ctggcaaaag catcaggatc tttgcgatga catatgcacc atcatccaga aaatagtttt
     4201 ccttgaatgc agcgtgtccg cttgtttcga tggctagctg tgtatctttc ccaagacggt
     4261 taagttctaa tgctttattg attacatttc gatagccgga aatataacga acttggatgc
     4321 ctcctttttc ttcaatgaat ctttgtagat gagaagaagt aggggaattc gtcacgattc
     4381 ttgttcctgg atgctctttt aatacgattg tacttaatac tgcgatcaaa ttatttcgat
     4441 tgatcactgt tccagaagca ctgacaactg cagaacgatc cacatctgta tcgaaaatga
     4501 tcccaagatc tgcttcattt gctaaaacag cctgcttgat actttccatc gcttctttat
     4561 tatcaggatt tgggatatga ttaggaaatc ggccatctgg ttccaaaaat tgggaacctg
     4621 ttgaatccgc acctaagcta ttcaatactt tttcagcaaa gaatccacca gcaccatttc
     4681 cggcatcaac aatgattttc caaccattta gtggtttgct ttctagtgtt ccaatcccct
     4741 ttttaatttt tgtgactaaa tcttgcgcat aaggtgtcaa aaggtctgct ttttctacgc
     4801 ttccagtttg ttcgcttttt attttttgct gctgtgatag gataaaagca atatcttctt
     4861 tttctgctcc tccttctgag gtaaagaatt ttattccatt ataataatag ggaagatggc
     4921 tagcagtcag cataaccgca gcatcgcacg agaactgttc aaattgagtg gacataaaca
     4981 tagcaggcgt agtagctaat tcgaaatcga tgacatgtat cccttgttct ttcagacttt
     5041 ggatcaacgc ctctttcagt gctggtccgc ttatcctact gtcatgacca atcccaatcg
     5101 tccatttttt atttggatcg gttgatttct tctttttctt tatccagttt gctagtcccc
     5161 agccgatctt ttttaccatg tctgtcgtca agtttacttc atatccttca actggtaatg
     5221 cgattcctcg aatatccgat ccattttgca gcgctttcat atctttcata taaaagtcct
     5281 cctcatttat tccctcattt tttccagctt ttctgcaaat cgctgtgctt cttcttctga
     5341 gcggcaaata ataatgaatg tatctacacc ggccatcgtt ccgacaactt cagggtaagc
     5401 cacttcatct agccaattcg ttaccacatc ggcaccattt cgttcagtca atacgataac
     5461 catgaactga acagactgga tacgcaaaac ctcgcgtcta attgctgtac gcaaacgttc
     5521 ttcatttaaa gaaacagatg gctggttaaa taatgtatag cgtactattt tgttttcatt
     5581 ttgacttttt actaacttca tttctcgaat gtctcgagaa atcgttgctt gagtcacatc
     5641 ggcgcctgct tcatgcagcc gcgcaagcag ctcttcctgt gtcccaatag gttgttctgt
     5701 aatgatctgg cggatcagtg cttgtcgctg tttctttttc atattagaca cctctcaatg
     5761 ttgattatag caaaagataa gtaatatttc ttcatatttt ggtatttttt acttttattt
     5821 tttgttttca ttcaggttgc taaccttttt ctattttaac acgcaaaatc gtcttcattt
     5881 tttcaggtgc tgattttctt ggatcgctga tgtaaatctc tttgtgttct ttagaagctc
     5941 tttcatagcc ttcttttgcg atgaatgctt ctaatttctc aaacgttgct ggttcttcgg
     6001 catagggccc gacgtgtaag atttgggcac aaagaccttc ttccatcttt ttgaatacta
     6061 cttgttcttt caagtcttcc ggaagtttgc tagaacgctg aatggcttct tgtgctatcg
     6121 cttctgtaac aaagtcaggc tgtcggatca tcaattgata agaaaaatgt tcttttttca
     6181 tcactggttc atgcaaatac ttttcttgca gtccccattg tccttccagt ggatagacag
     6241 tatacatctg ataatcagga atcagccaat tttttttagg cgacatgcgt attgcatagc
     6301 tgactgcata tagacaggct actcttcgtt taaagtcttc ctgattcggg tcgccgatcc
     6361 ctctgatgct aaagaatgat tttttaggaa cctctagtat ttgcgggctt tttttcatac
     6421 tatagctctt gtctttacgc cattcaattt tttccatttt tcttcctccg cgaaattcca
     6481 tttagttatt tattatcata cctctttttg agtgacttgg ctaatcgtgt tgacactatt
     6541 tttcagtttg tgctagaata agtgaagtaa ataaatcgta cagataacac gtttcggcgt
     6601 gtcgagagag aggcggtttc tatttttata atagaaatca ctctcttttt ttacgaaatt
     6661 ttttagaggt gatgtaaatg acaaaacaaa aacagctgct tttagtacct gcagtaattg
     6721 caacagggat gatgtctttt gcgggcgtat tgatcgagac ggccatgaat gtaactttcc
     6781 caactcttat cagacagttt gatttaacga ctgcacaagt ccaatgggta acaacgattt
     6841 atcttttgat gatttcgatc attgttccgc tgtctactta tttgaatcgc aattttagtc
     6901 tcaaaaaact ctttttagct tcaaatctgc ttttcttggc aggtataatg atcgatttct
     6961 tctctcctac cttcatggtc ctattgtttg gtcgattgct ccaaggtgca gcgacaggta
     7021 tcgctcttcc gttgatgttc catattatct tgacatttgc ccccctcaat cgacgaggcg
     7081 cgatgatggg tgtcggtact ttgacaacgg ccattgctcc agcaattggc cccacttatg
     7141 gaggcattat gacttcacat tttacatgga atcatatctt cctgtttctt gtgcccgttt
     7201 tgtttctttc tttgattatc ggctggtttg ctattcccga gatggcagta caaaaaagtg
     7261 gttatttgga ttggataagc gttttaggaa tttgtctttt gtttagtgga agtctaacat
     7321 ttttgagtac gttgggaaca gtttccagct ggattgcttt aatcatcggc ggtattggct
     7381 ggttcctttt ttactatcga agtaaaaaag tggagcatcc actgatccga ctgtctattc
     7441 tttcaaataa aacattccgc ttgtttttga ttggcttctt agtttatcag tttttattac
     7501 ttggtgtatc ttttgtcttg ccgaatttcc ttcagatcgt tcaaggaagt agtccttttg
     7561 tcgctggatt agcgatgctt cccggcgcag cggttggtgc tttgctttct cctttttccg
     7621 ggaaaatgct ggatcaatat ggtccgaaga agccaatttt tgctgggctg attctttctt
     7681 tgattggttg gctagcatta ttcctactca taggacacgc ttcagtgggt gtattgattg
     7741 cttgtcatgt gttttatatg atcggtatcg gattatctta cagcaatatg atgaccaccg
     7801 gaatgaatgc actgaatgaa gaactacaag gagacgggaa cgcaatgttc aataccttgc
     7861 agcagttttc tggcgctgtg gctacttcat tagtagcggt cattatcaat tacgtccagc
     7921 atcatacttc ccataactat gaagtgtcta ctacattagg atcaaaagca gcattaggcg
     7981 tcttgttgct gttgcttctc gtaagctttg ctcgattcgc ctattatctg ttctttgcta
     8041 aaaaagcgta gattccatat acggcaggtg ttgcatctgc cgtttttttg tgtgaaaatg
     8101 gttgtttgta aaaggaggct tttttatgga aaaaattgcc attatcggtg gcgggatcat
     8161 tggtatgacc ctagccagtt acttagatac atcaaaattc aatgttgctt tatttgatga
     8221 agggacagga caggcaacta aagctagcgc tgggattatc tccccttggt tgtcgaaacg
     8281 cagaaacaaa caatggtatc gtctggctaa agacggcgct gcttttttcc ctaaacttat
     8341 aaaagatttc caacttgatc aaacgattta cgcacaatca gggacacttt tgcttcgacc
     8401 tgaaaaagat ttagctgaat tggctgttct tgccgagaaa cgaaaagaag aagcgccaga
     8461 aattggaaac atcgaatggc tttcacctga acagacatct caagcacttc cgttattgaa
     8521 accagcagtt tcactgcgta tcagtggtgg tggtcgtctg gatggaaaag catatttaga
     8581 acatcttggt cagcgtttag cacaaaaaca aatggagcag atccaggcaa aagtcacttt
     8641 gcataagaag agcgattctt ggctcatcaa gggaccgttt ggagaataca cagctgatcg
     8701 tgtaattttg acacctggcc cggcacttaa gcctttatta caagaattag gctatgctgc
     8761 agatatacgt ccgcaaaaag ggcagctctt agcatttcag acatcttata agatgagtca
     8821 agactggcct gttgctatgc ttgacggaga agctgatttc attcctttca tggatggaaa
     8881 gatcctttta ggtgctaccc atgaaaacga tcaaggctgg gatttggctc ctactagcga
     8941 agcttataag ggattgacta agagtacaga acagttcttg actgatccag atcagataaa
     9001 aaactggcca tacgagttcc gtgtaggtac ccgtgcttat acgtcagatt tttccccatt
     9061 tttcggcgta ctgccagatg atccaagctt actggctgct agcggtctag gctcttctgg
     9121 cttgaccaca ggtccttata tcggctatct attagccaac ttcttaaata ctggtcattg
     9181 gcctacggaa gattatcaaa aggacatctc cacctatatt acgaaaaatc catcatagaa
     9241 aaacagcttt ttcaagtaag gatcccgagc gatattgcgc atggattact tcttgaaaaa
     9301 gctgttattt tagttcaatt tctgaatcaa attctccaaa ctttcttttg cttcatctgg
     9361 caagagatct tttcctatct gagcttcaat gaatcgtaaa cgaatatcaa gtcgttgttt
     9421 caccagattt ttataggacg tatcctcaaa agaaacagga aaatctggta taggtaaata
     9481 gtggatgtct tcaaatggac caaacgactt gaattctgcc gtttgttgca cgattctttc
     9541 aacgattgac aatgtcgttt caggtttgat ttttttatca tcgaaatatc cagtattcag
     9601 gacatagcag gctgtttgct gtttcaaaaa caactctcga aaagcttgat agtcttccct
     9661 aagaggatag acacggaaag gattagcaaa tggttcaatg actagctcat ctagctgtct
     9721 ttttgtagtg atattttccg cgtctgatcg ttttgttgct aatgttgcac caaaagacgc
     9781 tgctaaaact gggtcattga tcttgataat tggcggaagc gaatcatctt tcatgatcca
     9841 aaaaacagca tcgatctttt cgctaagatg atcgactcgg tcgggtgtcg cataacgtga
     9901 tttgactgtc cgcccatttc cgtttcgtat atctcctgtt actaggactt tttctccttt
     9961 acttgtacat gtcacgccca cattctgaca agtaaggaaa gaagaaatgg ccggatcatc
    10021 agacggatag tcttgtgttt tatcaaagta agaaggttcc aaggcagtag caaaaccatt
    10081 ttttcgagaa ataacgaaag catcgtcatg caagatcgaa acagagtgac cttccgtatg
    10141 ttttgctaag gtaatcgttg attttccaga accggacaac ccaaatacag ccatcgtata
    10201 ggtctggtca ttactagcat attgtttcat cccaccgtgg caggcaataa agccattgcg
    10261 atttcccaat gcccaagcaa gcgtcaaagt cgcttttttt aattctccaa agtaacgtaa
    10321 tcctagcaca gccgctgtat tatggagagc atcaaacaaa atgagtccat ttggaaatgt
    10381 ttcatgtgtc cattcgggat cacaaaagat ataaagatct ccctcatcaa aggaaacaga
    10441 cttttgataa gtctctaaga tcttcgaatt cgctggctga aaattcagca aataagaata
    10501 caaattgttc tcaaatcctt ctggaatcag caaatgactt tgcacagaaa attcttcaga
    10561 taggccaacg attacttttg tatggtaaaa ctggcgcttg cgactttgat acacagcttc
    10621 tcttaaaatt ttctcgtatt tgctttgttc cttgtctaag tcctcaaaga tccgccgagc
    10681 acttgctgtt cttcccacaa tgcttccatc attgaatact agtgtcctaa catcagctgg
    10741 taaatctagt tcttcagcat gtgagattgt taaatctgtg atgatcgttc ctggactccc
    10801 ttttgctagt tgataagctg tcttcctatc aaaaacttca tgaacattat taccgtaaaa
    10861 tgtcgtttct acaatcgatc gaatactgga taacagtgga tttccacttg tgatttcgtt
    10921 taattcgaga ctctcttttg tactcatggc tcctcctcat tccctaaaca aaaaaacgtt
    10981 ttctttatta tacattattc gagtttttat ttgtactgct gcgctgtggg aagcaaacga
    11041 gttatttttc acacaaaaaa accgagaact tgaataaaca agtttctcgg tttcatcatt
    11101 ttccttttat cggcttagta ccagccgttt gctaaccaga atgttttagc agcatcccat
    11161 gaaccataac gagatgttac atattgttct gctacacgtt cttgattggc agctgaatag
    11221 tcgccgttta agtatgaagc atctaattga taacggccga tgtaacgtcc gttagtagct
    11281 gtgtatgaac cgcctgattc tttttgtgcg atccattctt ttgcagagct tgaagttggc
    11341 gctgttgcag cagctggggc agcaggagct acttcaactg tttcaacagg tgcaacgtat
    11401 gtatgttctt gcgttgctgt ttcagttgta gatgctgtat tttctgttgt tttgttttct
    11461 gttgttgctg aagaatcatt tgaagttggg attgttaatt gttcaccaac ataaatgcgg
    11521 ttgatgtttg cgatcgaatt tttttcagca attgcatcga tcattgagtt gtctcctgca
    11581 aatttttgtg agatcttaga taatgaatca cctgatttta ctgtataaac ttcatcagcg
    11641 tgagcatttg tagttcctac aaacattgca gtagcaccag cagcaaaagt tgtacctaaa
    11701 acaattttct taaatgaatt catattaaac tccttttttt ctccgttttt tattctttcg
    11761 acgctattaa ctttatcatt tagaaatatt tcataggtaa aagaaacatg acatttaatg
    11821 acaaaataac gaattattta atatttgtaa catttaaaca aatatttttt tgatacaaaa
    11881 ccataaaagc cttgttgtat aagcaaagta atcgtttttc tatgtttttt tatttttgaa
    11941 tgaaaaacgc agattctgta acattcactg caataatcca taaaaaaaag caaaaaaatt
    12001 tttgattttt atcaaattct cttaaaaaaa tgtaaaaaat acaaaaaaac cagtaattgt
    12061 tacaacaatt actggacaaa aactttgaat aatgttaact atttttttat tttaactttc
    12121 tccgcaataa tttctgggca tgttccaatt cgtttataac gacttcttct gtttctttag
    12181 ctaatatttc atctaataca tcaagccatt tttccggttc ttttgttcct agacgtccaa
    12241 tagcccaagc tgctgttcct ctgatgacag ggcggacatc tgttaaacat tctgaaatct
    12301 caggcaatgc cgttcgatca cctagattag ctaaagcaat caatgcgttt ctctgcaaag
    12361 gtttcttccc acgccatgaa ccagctaaat gcccaaattg ctgtttgaag tctttattag
    12421 acatcgaaag cattggcttt aattttggat atatttcgtc tacttttggt tccatctctt
    12481 catgaaaatg aaaatctttt ccttgattgt aagggcagac taactggcag atatcacatc
    12541 cataaatgac atttcgcatt tttttacgat attcttccgg catcatccct tttgtctgag
    12601 tttgataaga caaacatcgc tgggcattca ttcttccgtc accaagcaat gcttttgtcg
    12661 gacaagcagt cacgcagcgc atacagtcac cgcaaccaaa ttctcctggt ttatcaggct
    12721 caaatacaat attagtaacg atctcaccaa gatagacaaa tgaaccgaac tcttcagtga
    12781 tcaacaatcc gtttcgtcca ataaatccta aaccagctcg ctgtgctaca gcgacatcga
    12841 tcagttctcc agtatctact tgcggagcta gacgccattc ctcttctttt tgccattttt
    12901 ctgctcttgt ttggatgaat tcgatcaatc ggttcaaacg gtctctgagt atatcatggt
    12961 aatcgatccc ccaagaagca cgagcaaact gcccgcgttt ttcatcccta ggcacttctt
    13021 catggatcct agtaggatac gcaagtgcaa tggaaatgat cgatttcggc tgatcaaatg
    13081 tcatttctgg ataaagacgc tcatcgatat ttggatgttc aaagccagaa gtatggccag
    13141 ctgctttttg ttcttccaac gattctttta atgaatcaaa aggttccgcc gtggtgaacc
    13201 cgattttgtc aattcctaat cgtttgcttt cttgtatgat ttcttctttt aatgtcatgg
    13261 tcttcctcgc ttgctgttaa cggctgtata acccataata tagtttttct tttttcagct
    13321 ggacaaactg gatctgctga tcggcaatct tcttttcttc catccatttt tttcttgcag
    13381 caaatacttc ccaataattt gttgaaatta attttctttt gttatctaat gcattaaaaa
    13441 aattcaatga aactggtttt gtacttaaca gttcatggag ccttacctct tcccatggcg
    13501 aaaactcaga cagatcgcgg gaatacaata cttcttcata gagatttttt tgctgtgtgt
    13561 acgtgaatgt ttgcgggatt ttcccaggcc tagcaatttc tactagacga ttataaaaca
    13621 tattcattaa tttgctgttg gcaataaatt gacttttata ataggccgac tggatctttt
    13681 tgattactcc ttctgctttg atgactgaaa ataatgcagg ccatgctttg acggttattt
    13741 cgtcgttttg tttaactaat acgccaggtg tgaagccgac tggagaaagg aacacaaaat
    13801 aaccgatacc ggtattttca tctaaaggct gaaattcatc aaacaaccat ttgcctatgt
    13861 acagctcttc atctggttct gttgtctcat tttgatttgc tatgaataat ttagctaatt
    13921 ctgcttcaag aaattgaagg tcttgatcct tgtcggtatt ttcctgctgg ctgatcaatc
    13981 gaaagacttc ttctttaatc gtatatttat ctttacgtgt aaaattcata gccacacctt
    14041 ccttccttac tctaactata acggaatttc ttcaaaaaag gtatctgtac gacgaaaaac
    14101 agcataattt tttttcatat ctcttataaa aaatgcaagg tctgctcctc aagctagacc
    14161 ttgcactttt cagctttctt ttgtttgtga caaaccttca tggatcgttt caatattcca
    14221 tttcatcatc tgatagtaag aatctccttg ttctccttct tttgctatgg aatcagtgaa
    14281 cagtttatca tagattttca aacccgtttc ttttgctacc cgttccatgc ttcttgagtc
    14341 tacactggtt tccacgaata aaaccggtac ttcttttgct cttatctgat caatgatcgc
    14401 tttcatttga tcaggcgtac cttgactttc tgtattgatc tcccatatat aagctgctgg
    14461 caaatcatat gctcgtgaaa aatacttgaa tgccccttca cttgttacta ataatttttt
    14521 gttctcttcg atagaagcaa aactttcctt cgcttgtgta tctaattctt ttagtttttc
    14581 cacatatgct tctgcatttt ttttatagag tgtcgcattt tctgcatctt tttcagagaa
    14641 tatacgtgcg atttcctcca catattttat tccgttagat aggtctagcc aagcatgggg
    14701 atctgctttt gtatgttctt caccgctagt taaataaaga ggttctacat ttttgctaac
    14761 tgcaaaataa tcttttcctt cttctttttt agccgtttcc atcaagttat cgaaccagct
    14821 gttacctgtt tcaagattca aaccgttgta taaaataaca tctgcatcgc ttgccttttt
    14881 gatgtcttct ggtagtactt catattcatg cggatctgtt ccgactggta cgatactgtg
    14941 gatatctatt tgatctgttc cgacctcttt tgccatgtcc gccaagatcg aattggtagc
    15001 cacgactgac aacttttctt tacttccttc atccgcttgg tcagaagcct gctttccgca
    15061 accggctaat accaagaaac taactgccaa gattaaaaag agtgattttt ttgttttcat
    15121 ctatctgctt cctttctgaa ataaaattcc ttttgttgga gaaaataaaa aagcaaggat
    15181 aaaaaatgcg gtacatgcta acacgatcgt agctcctgat ggccaattgt aactataact
    15241 gaaaaacaca ccgacaactg cacttagcat accgattcct gcagctgtaa tgatcatttt
    15301 cagtaaatgg ttcgttagca agtaagccgt ggcggctggt gtgatcaaca tggcaatcac
    15361 caagattgtt cctactgtct gtaaactgac tacagccact aatgtcaaaa agaacatcaa
    15421 aagataatgg atcagcgatg tgttcagccc ataagctttt gccattgtcg gatcgaatga
    15481 tgtgatcttc aattctttat aaaagaaaaa gacaaatatc aagacgattc cactaacgag
    15541 tgctgtcagc aacaaatcgc tttccctaac agctaagaca ttcccaaata aaatatgata
    15601 caaatctgtc gcactctggg catatgaaat caagataatc cctaatgcaa aaaaggagct
    15661 aaagacaatt ccaatcgctg tatcattttt caatcggctc cgctgagtca cgaaaccaat
    15721 cactgctgct gttagcatcc caaaagcagt ggctccaaag atgtaactaa aaccaaacat
    15781 ataagaaatg gctacacctg gaagaactgc gtgagagata gcgtctccca tcaaagacat
    15841 ccctcgtaaa ataataaaag aaccgatgac tccagaagca agtcctacaa gcatggaagt
    15901 gaccaaagcg tattgcagga attgataatt cattaatcca tcaataaagg attggatcat
    15961 tttttctctc ctccttttac taaatgtctg atgatctcac cataggccaa ttgaaggttc
    16021 ttcgatgtaa agacttcttg tactggaccg gaagcgatca gctgtttatt taaaagaata
    16081 acctcatcga aatattcttc tactttatga agatcatgat ggacgatcaa aatcgttttt
    16141 cctgaattct tcaattcctg caagatgtca aagatctttc gttcacttaa cgcatcaatc
    16201 cctacgaatg gttcatctaa aaagatccat tctgctcctt gggctagagc tcttgcaata
    16261 aaaactctct gaagctgtcc acccgatagt tcgctgatct gtcttttggc atattcttcc
    16321 atccctactt ttttcaaagc ttgtcttgca cgttcttttt cttttttccc aggtctttgt
    16381 ccaattcgta aagatggata tgttcctaaa agtacaacgc ctaatacatc aattggaaag
    16441 gaaagatcca attcacttcg ctgttccacg taggctattt ttttacggac tgagtttacc
    16501 gactgtccag aaaaggtgac tttaccagta gtagctggta tcaactctag caaagatttc
    16561 ataaatgttg attttcctgc accgtttggt ccgataatac cggtaatttt ttgtggattt
    16621 atcgtcaagt tgatagtttt caaaacagtt ttcccttgat aagcggctga aaggtcttga
    16681 attacaatgg ccgtacgttc caaatcttac actccttttt aggtttacct aactttttat
    16741 ttaaatatag tttaactaaa atggaaagca ttttcaagta gaatgatgaa aaagtttttt
    16801 tcgaattttc ctcgcatttt atgaaaattt tctgtagaat cacatcaaga gttcaataag
    16861 gctaacctaa taatgaaaaa catgtgttga aacgtttgat tattttttct tgttgactca
    16921 acaacgaaag gagtttttgt atggaagaag aaaagttaac tcgaagtctt agtgcccgtc
    16981 atatccaaat gatcgcacta ggtggaacga tcggtgtcgg tctgtttatg ggtgcctcct
    17041 caaccatacg ttggacaggg ccctcagtga tgggagccta tgcgattgca ggattctttt
    17101 tgtatttgat tatgcgtgct ttaggcgaaa tgctttacgt tgatccttcg actggttctt
    17161 ttgcaaatta cgcgagcgag tacatccatc ctgtggctgg ctacttgacc gcttggagta
    17221 atatttttca atatattgtc gtaggaataa gtgaagtgat tgctgtagga tcttatatga
    17281 attattggtg gcctgatttg ccggcaatta ttcccggaat cattgtcgtc ttgtttctta
    17341 tgctggcaaa tcttatttct gtcaaggcgt ttggcgaatt agaattttgg ttttcgatca
    17401 tcaaagtcat aacgatcatt ttgatgatca ttgcaggtct tggggtaatc ttatttggat
    17461 ttggtaatca tggtcaggca gtagggattt caaatctttg gaaaaatggt ggattcttca
    17521 ctggaggcgt caaaggattt ttctttgcat tatcgatcgt tgttgcttcc tatcaaggaa
    17581 tcgaactgat cggaatgact gctggtgaag cagagaatcc taaaaagacg atcattgaag
    17641 ctgtccagtc cactatcggt cgaatcttga ttttttatat tggtgctatt tttatcattg
    17701 tgagtatcta tccgtggaat caattgagtg agattggttc accttttgta caaacttttt
    17761 ctaaagtcgg cattacattt gctgcaggac tgattaattt tgtcgtgatt acagcggcat
    17821 tatcaggttg caattcaggg attttcagcg caagtcgtat ggtctataca cttgccataa
    17881 atggaaagat gtctaaaaaa tttctgaaac tatctcgtca cggtgcgcct ttttatcctg
    17941 tcgtagcaat ctcaggtgga atcttaattg gtctgatctt aaattatctt ctaccaatgt
    18001 tcatcaacca gtcagaaaat attttcgttt tcgtatacag ctcaagtatt ttgcctggta
    18061 tggttccttg ggtagtgatt ttgatcagcg agattcgctt caaaaagaag cacgcagata
    18121 aaatgcatga tcatcctttt aaaatgccac tatctcctta tacgaattat gtgacacttg
    18181 cttttttagc tatcgtattg attttcatgt ttatcaatcc tgaaacgaga atctcattga
    18241 ttattggact cgttttcttg ctttacatga cgatccatta ctttgtacgc gaaaaaagaa
    18301 ccggaaaata aaaaaagaac gaagcttcac cttagtggaa gcttcgttct tttttattgc
    18361 ttttatcaat tcaattttag cgtctcaccg ggagtcagga aataattctc catgctcatc
    18421 ccattcagcg acaagatcgt ttctactggt acgccagttc gttcggctat ttgatttgga
    18481 ccttctcctt ccaaaactac ggttgtcgca gcctgtgaag tcgcgctgtt ggtattagtt
    18541 tcagaggaat ctgttgtgtc ttgtgttgtt cgagcttgca tttcagaagc ttctaccgac
    18601 tctgctgtct cagaatcaga agatgttgtg tcttgtgtgc ttgttgactc tgcttgaaga
    18661 gaggcgctag tctgcaaata aatatcggaa atcttagcga catgattcgt ataattagcc
    18721 gataattgat tgatcaaagt atctaagtct acaccgtctt tattttctgc tgcctgatac
    18781 gctgcacgta attttctgat cccttcgtcg gagattgctt gaagctcacg tgctttttgg
    18841 ttagcaactg ctgataaacc agctattccc tcttgatttc cctgaatttc tgtctggtat
    18901 tcttcaatca atgcaggcgt cttttcttcg atctttttcg aataatcatt tacgattgct
    18961 tgaagttgct ctggcaaacc atttgctgtt ttttcttcag aagtttgtgt ctcttttgtt
    19021 ttagttgatg actcacttgt ttgtttcgtc tctgttttct ttgtcgttgt ttccgttatg
    19081 gtcgtacttt tcgcttctga cgaatttttt ccatgaaaat atagacccgc aactcctcct
    19141 gctatgatca aaaacacggc aactgctgcc ccaatcatga tcatccgctt acgagctgcc
    19201 tgtttttgct gtcttcttcg ggtcatccga acattttctc cccactcatt ttcatcatac
    19261 atttttttca ccaccaattt ttatgtataa tagcgttatc aaacgcttca tattcttatt
    19321 gtagcaaata attgtcgctg tgcacatttt tatctttgtt atttataaga aaatttcacc
    19381 agttgagatg attccaagat tgtccgtcga tttctccttg cagctgcatt gttcgttcgt
    19441 ctatctcagc catcagtttc tttatttcat ataagagcgc acggtcttga tattctgatt
    19501 tttcgcttaa ttcatctaat tgttggatca gccaatcatt tgtcataatg aagttccttt
    19561 catttcttgc agtgtaaagg tcaagtcttc gatctgctct tttgcctcag tcagtgcttc
    19621 tacgatatat gcttgttttt cagattcttc ttcctgcatt ttctgatttt cctgtactct
    19681 ttgaataaac cagtcaatcc gctgagtcag cgatggtttg ccttccaatg agagatactg
    19741 ctgataagca attagcttct cccaacgttt ttcctgggat aaatacataa attgtgctaa
    19801 aacgaatggc ggaagatagg tcatatggaa tttatttgcg attcgctgat acggcctcaa
    19861 aaattcggaa atcgtatatt cttcttttcc tccagcttgg tattcttttt ccgccacacc
    19921 tgttgtcaat acgattccta gttctttccc ttttaataca tgtgctgctc gttccaagac
    19981 attatcttgc caaattttta aatgagcagg agaactatac cagtaaaacg gaaactggaa
    20041 aatgatccga tcatgctggg ccaagagctg tagttcagtc tctatatcta tttttccgtc
    20101 tggataactt gattccaaat gatgccaagt agctggtaaa ccagcagaag cttctttgaa
    20161 aaattgctga tttaaagatt cttcgatcgt tggatggcta atgatgataa gtgtacgcat
    20221 cccttttcct cctttttagt cttcgcttta cagtgtagca taaccgccac aagtttcttt
    20281 tgccgatgct tgtcatttta accagactaa tcaggttgtc caagaaactg cggtttgttt
    20341 ttccaactgt tttttcaagg tatccaaagc aatattctta aaattttcgt ttttcatacg
    20401 tttacgatag ttcgtagccg tttctccggt actctttttg aacattcggc taaatacgac
    20461 tagactattg aaccctactt gataggcaat actttccacg gattcatccg tcagagaaag
    20521 aagaaacgcc cctcgattga tccgtacccc gatcaaatat tccttgatac tggtacccat
    20581 atgatttttg aatactcgcg acaaatggct ccgattgacc gctaaatgct gggcgatttc
    20641 ctcaacagac aatttttcag cataatgtgc ctcgatgtat ttgactgttt caacagctaa
    20701 agaggaatga accttttgta caccaccgct gacctttccg ccatctttta aaaggactga
    20761 taaaaaacgg taggttaatg ctgttaactg taattcattt tccaaggttt cttccgtatc
    20821 tttcatgcat tctaaaataa tgtcgatata tttttgtatg tcagaagaga ccatcgtgta
    20881 ttggtcttct ctgaaaagcg actgccgaat gatttcttct gcagcactcc caccaaatga
    20941 aagccagcaa tacatccacg gatcttctcc atctgataag taaaacgtcg agtctcctgg
    21001 acgaatcaag aacagatcac cttttttcaa ttggaattgt tgatttttca catgataaga
    21061 tcctttgcct tccatcacga catgcaggat gtaatcattg cgaatagcag gaccaaaaga
    21121 atgaaacggc atcgttttag agaaaccaca aaaatcaaaa tacaattctt tttctacttg
    21181 ttgatgttcc ttttttaaaa aaatcgattg ctccacgtct atccctcctt actcctttag
    21241 tataatgcaa caaaaagtta aataaaagtc acagaaatat attaaaaagg aagcgatttc
    21301 ttgttaagtt taagtcatta aaagatcttt gttattcgtt gtaaccggtt tacttagtat
    21361 tatatattga acaggagagg aatacagatt atgaaaagca aaatgatcca acgtgtgtcc
    21421 tacgctttag gcgcttttgg acacgacaca ttctatgtta cattaagcac ttattttatg
    21481 gtattcgtga caagccagat gttcgcagga acagataagg caacgaatgc aaaaatgatt
    21541 gctacagtta caagcttagt tgtaggtatc cgcttagttg aaattatttt tgatcctttg
    21601 attggtggca tcatcgataa tactcgtaca aaatacggta aattcaaacc atggttagtt
    21661 atcggcggcg ttgttagttc cgtactcttg gtagcaatct ttaccaattt ctttggctta
    21721 gctactcata atacgacttt atttatcata ttatttgcaa tcgttttcat cttattggat
    21781 agtttttatt catttaagga tatcgctttt tggtcaatga ttccagcttt gagtacggaa
    21841 acaaaggaac gtgaaaaatt tgctacgttt gctcgtttcg gctcttctct aggtgcaaat
    21901 ggtactactc tagtcgttgt ccctatcgtt actttcttta cctatcttgt tactcataaa
    21961 catattgaag gcgcttcagg ctggttctgg ttcggtgtga ttgctgctgt tatttcaggc
    22021 ggtactgcga ttatcactgc cttgggcaca aaagaagtcg atactgcgat ccgtcagcaa
    22081 aatgaaaaag ctgggatcaa agatgtgttc aaagcagttg ctcaaaatga tcagttgatg
    22141 tggcttgccc ttgcttatat cgcttatgcg attgccaatg cagcaacaac tgccgtatta
    22201 ttctacttct tcaaatatgt acttggccaa ccaactgaat tttggatcgt tggtctagtt
    22261 gctgccttac ttggtttagt agctgttcca ctattcccaa tgcttacacg cgtcatctct
    22321 cgtcgctacg tttaccttgg agggatcgca atgatgattt cttcttactt tttctttacg
    22381 atcgcaggtt caagtttgcc aatcgttatc atcgggctag tattgttcta cttccctcaa
    22441 caattgattt tcttatccgc tttgatgacg atcacagact ctgttgaata tggtcaatgg
    22501 aaaaatggta tccgtaacga agctgttact ctatcaattc gccctttact agataaaatc
    22561 gctggtgctt tgtctaacgg gatcgtaggg tttgtcgcta tcgcttctgg gatgactggt
    22621 aatgctactg ctgctgatat cactgctcat ggcgtaacga ctttcaaagc ttatgcattc
    22681 tatgctcctg ctgctttgat gattttctcc gctattattt ttgcttggaa gattacattg
    22741 acagagaaaa aacatgcaca aatcgttgag aaattggaaa acaaattggc tccagctgat
    22801 acaatggaag attaacttca cgatgcagta gttccttccc attaagaaag gatcttgaaa
    22861 atgaagatta cagaaaaaga ttttggccaa ggttatcact tgataacctt ggagaacaaa
    22921 aacaagctag cactttctat ctctgattta ggtgctagaa tcgtcagttt aaaatcaaat
    22981 gatcgagaat tagttttggg atttgacacc gctgaagaat atatcgaaaa agatccgtat
    23041 atcggtgctt ctatcggtcg caccgcaggg agaatcgaaa atggccgctt ttctctcaat
    23101 ggaaaaactt accaattagc cacagatcca aaaactggac ataatctgca tggtggtgct
    23161 cctggatttg aattaaaaaa atggtcttat gtcattttga atggcgaaaa tgaagcttct
    23221 gtcattttta ctactacaag tcccgacgga gaacatggtt ttccaggtac aatggatgtg
    23281 gaaatccgct atactttgac aaaagataat atctggcgag tgacctctcg cggcaccagt
    23341 gaccaagata ctttattcaa tccgacaaat catgtttact tcaacttgac gggagatgct
    23401 tctcagtcaa tcgatcaaca tgagctttgg ctcaatagcg aagcttatgc tcctttgcga
    23461 acagatagta ttcctatagg ggtaaaagaa aatgctgcag gaagtgcttt cgattttcaa
    23521 atacctaaaa aattagcgtc cgtttttgct agtgatttgg atcaaaaaaa tcttgttgac
    23581 ggaatcgatc atccattttt cttaaaagaa accggcttgg gtaaagaagc cgctcgcttg
    23641 actagccccg ataaaagaat ccaagtagat attgctacag atgcttctag tgtggttatt
    23701 ttcactgcaa atttcggcac agaaacacca gaaatgcgca accgaaaact ggcacatcac
    23761 ggtggcatca catttgagac tcaaacagct ccaggtgcag agcgcttctc agcatttggt
    23821 tcgattcatt taaaagccgg atcagtattt gaaacagtaa cagaattcaa aatcaaaaca
    23881 agaaaggaat aactcatcat ggaaatcaaa agaagcttaa acacaaaatt tgccgaaaca
    23941 ttcggaccta aaaaaactac acaatacttc tcaccaggac gcatcaattt gattggtgaa
    24001 cacacagatt acaatggagg ccatgtcttc cccgcttcca tcacttatgg aacgcaaggt
    24061 gtagcagcac ctcgagacga taataaaata ttagtttatt ccacaaactt tgacgatatc
    24121 ggtgtcatta gttttacttt agatgagcta gaatatgata aaaaagcaaa ctgggcaaat
    24181 tacgtaaaag gaatggtcct taaattaaaa gaagctggac actcaatcga tcatgggttt
    24241 gagttattag tggaaggaac aatccctaat ggtgcaggac tttccagtag cgcttcatta
    24301 gaattattag taggtgttgt attagaagat ctgtttgatt taaaaacaga tcgcttggaa
    24361 ctagtccaaa caggtaaaaa agtagaaaat gaattcatcg gtgtcaattc aggtatcatg
    24421 gatcagtttg ccatcggctt cggtgagcta gatcatgcaa tcttattaga tacaaatacg
    24481 ctgaaatacg aaatggttcc agtgaaacta gatggttatg caatcgtcat catgaatacg
    24541 aataagcggc gggaattggc agattcaaaa tacaatgaac gccgtagcga atgcgaagaa
    24601 gccttggcac gtttgcaaaa aactttgcct atctcttctt taggagactt agatgaagaa
    24661 gaatttgaat caactattga ccaaatcggc gatgatacat tgatacgcag agctcgccat
    24721 gccgtttctg aaaatcagcg gactttgaag gcaaaagctg aattagaagc tgggaactta
    24781 gaagcatttg gtcaactgtt aaatgattct caccactctc ttcgctatga ttatgaagta
    24841 actgggatcg aattagatac actagtagat gctgctcaaa aacaagaagg tgtcttaggt
    24901 gcacgaatga caggagctgg atttggtggc tgtgcgattg ctcttgtcaa agaagaaaat
    24961 atacctgcct tcaaaaacaa tgtctatgat gaatacatga aagttgtcgg ctatgctccg
    25021 gaattttatg ttgcacacat tggaaatggg acaacaaaga tcgatccaga agctgttcat
    25081 gtttgataaa aaaatcaacg atctcagcta aaaacaaata gataaaaata acctctcagc
    25141 aatttccaaa tgtgagcctt ttgctcgtat ttgaaaattg ctgtttttta ttgacacgga
    25201 aagagaacgt gtgttctaat tgtgttgaag aggtgattgt tatgtgggcg aatcaaaatc
    25261 cggtatttgt ttatgaaaaa gaaccttcaa gagatatttt atgtattgac tgcaaatctt
    25321 tttacgcctc cgtagagtgc gttgaaaagg atcttgatcc ccttacaact aaattagtag
    25381 tcatgtccta tccgtccgat tcgacagaaa cacggggtag cggattaatc ttggcttcca
    25441 gtcctgcagc aaaaaaagct tacggcatca ccaatatcag ccgtgccaga gatcttccct
    25501 tcccctatcc aagtgattta tatattgttg ccccaaggat ggcctattat atggaaaaga
    25561 acagagaaat caattctatc tataaaaaat atgcagacga agcgaaccat catgtctatt
    25621 ccgtcgatga aagcttcctt gatgtaacaa atagcatggc actctttggt aaaacaaatg
    25681 cgtacgacat ggctaaactg atccataaag atgtgtttga gcagaccgga atctacacga
    25741 ctataggaat tggcgataac ccgctacttg ctaaactagc cttagacaat ggctcaaaag
    25801 acggaaagca aatgtttgct gaatggcgtt atgaagatgt accagaaaag ttatggaaaa
    25861 tctcagatat cactgacttt tggggaatcg gcaaacgaac agcaaaacgt ctgaaacaaa
    25921 tgggtataca ttctgtttat gatttagctc acgcggatta ttatcacttg aaaagcaagc
    25981 taggggtcat cggtactcag ctttatgccc atgcttgggg catcgatcga agttttttgg
    26041 gacaagaata tacaccaaaa tcaaaaagta tcggaaatag tcaaatccta gatagagatt
    26101 atacaagacg agaagaaatc gagatcgtta tcaaagaaat ggccgaccaa gtcggcactc
    26161 gcttgagacg atctgcagca aaaacacaag tagtcagctt atgggtagga tactctttag
    26221 gctatcttga tccaaatggc aagaccgggt ttcaccagca aatgaaaatc gaagcgacaa
    26281 atgctagcag agatcttgca gatgctttat tgaccatttt ccaccagcat taccactacc
    26341 aggatattcg gcgtgtaggc gtgaactgtt ccgacctcgt atacgcgaca ggtttacagc
    26401 ttaacctttt tgaagatcct gaaaagcaga taaatgaagc gaaagttgat tttgttgtcg
    26461 atacgattag aaaaaaatac ggctttcaat caatcatcca tgcgcatagt ctcttgcaag
    26521 gaggacgcgc catcgcacgt agttctctcg ttggcgggca tgcaggtggt atgagtggat
    26581 tagaaggtgg aaaagatgag acggacagca aaaaaattca ttgactataa cgagtatcga
    26641 gatcggccat ttggattaaa atgggggact gcttttgcga tggaagaact agtcaacggt
    26701 atcaaaaaaa tgaagaagaa gcacgcaaac agcctcttcc taaacaacaa atgacattgc
    26761 aagaaatcga tagtatactg acagaagcct ttttatctcg taaagcagta atcattcagc
    26821 tcaatttaaa agatgaattt ggaagactct tggatgaggt cgaagggcac ttcattggtg
    26881 aagcctatga agattacttt atgattgacc atcagccgat attgtgggaa gacgtacggt
    26941 atattgagtt aaaggaaaca aaaaaatggt ttgtgacatg agaggttgtg acagaagtga
    27001 tcaacttcaa aaaataagaa aggatttttc gaaaattgct tcttaaattt ttgtggaatt
    27061 ttggcttatt tttcgaagaa gcaacttctg gaacaacgta tattagatat cagaggttgt
    27121 gaaaaagtcg cttagttttg agtaacaagc caaggcgctg atttcacaac ctctgtctat
    27181 ctatccatct attcggtaag attcatgcat gacgtcttct ttatttagta tgtagagccc
    27241 tttttcttct gaccattcaa cataaatcag ctgttttaca tctgcatagc cttctttctt
    27301 caagttctcc ataagccatg cttcagtcaa ttgattggac tgaagcactt tatgctgaat
    27361 ttgcccttca tctacaagca ggatcgataa agctttgtct tcatctgatt ttttcaatac
    27421 actcatttga ccggcattct ctaggataac atgtttggca ttttcaagaa aaaagcattc
    27481 ttgctgtctt aagattgctc gcaactgctc catctcgata tggttatttg tcaactctgt
    27541 catgttgatg acgccgtctt tgattagaac agatggctcg cctttgaccc aacgattgac
    27601 cttttcattt ttttggacga tacgttcgat accataaatc attactgccc aaagcgcaat
    27661 ggcaaatagg acatgcccta catggacatt gtcatcatag gttgattctt ctaagatccc
    27721 acctaaaaca agcgtataga ctaaatcaaa cggtgtgatt tctgacatgg atttcttccc
    27781 aagcaaacgt accactaata ataaaccgat caacccgaac accagtttca ttgtaattga
    27841 aaaaatcatt ttttctcccc ctaactatct gttaattaaa ttatatatgc tttctcacga
    27901 acacgcatgg aatatacaag gaagaaatgt atccttttac taaaaaaagg actgtgacac
    27961 tgtagtgacc cccaaaagtt agactttttt ggagtggaga aatccactcc ttttttttat
    28021 gctctaaaat gatattttta cacaaccgtt acggttgttt tacgaaattg gacg
//
LOCUS       DADGHT010000029        26354 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.029, whole genome shotgun sequence.
ACCESSION   DADGHT010000029 DADGHT010000000
VERSION     DADGHT010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.029"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(99..1229)
                     /locus_tag="JX887_001124"
     CDS             complement(99..1229)
                     /locus_tag="JX887_001124"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAX1257129.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1878..3080)
                     /locus_tag="JX887_001125"
     CDS             complement(1878..3080)
                     /locus_tag="JX887_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1257130.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="JX887_001126"
     CDS             complement(3140..3343)
                     /locus_tag="JX887_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAX1257131.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="JX887_001127"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="JX887_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4880..5692
                     /locus_tag="JX887_001128"
     CDS             4880..5692
                     /locus_tag="JX887_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1257132.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6868)
                     /locus_tag="JX887_001129"
     CDS             complement(6716..6868)
                     /locus_tag="JX887_001129"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257133.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="JX887_001130"
     CDS             complement(7059..7937)
                     /locus_tag="JX887_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1257134.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="JX887_001131"
     CDS             complement(7976..9094)
                     /locus_tag="JX887_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAX1257135.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="JX887_001132"
     CDS             complement(9091..11190)
                     /locus_tag="JX887_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAX1257136.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="JX887_001133"
     CDS             complement(11241..12062)
                     /locus_tag="JX887_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAX1257137.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="JX887_001134"
     CDS             complement(12059..12868)
                     /locus_tag="JX887_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1257138.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="JX887_001135"
     CDS             complement(12889..13383)
                     /locus_tag="JX887_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1257139.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="JX887_001136"
     CDS             complement(13395..13883)
                     /locus_tag="JX887_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1257140.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="JX887_001137"
     CDS             complement(13960..16656)
                     /locus_tag="JX887_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1257141.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="JX887_001138"
     CDS             complement(17084..18157)
                     /locus_tag="JX887_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1257142.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="JX887_001139"
     CDS             complement(18154..18981)
                     /locus_tag="JX887_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1257143.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="JX887_001140"
     CDS             complement(18982..19788)
                     /locus_tag="JX887_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1257144.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="JX887_001141"
     CDS             complement(19800..20885)
                     /locus_tag="JX887_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1257145.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="JX887_001142"
     CDS             complement(20902..21444)
                     /locus_tag="JX887_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1257146.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="JX887_001143"
     CDS             21702..22691
                     /locus_tag="JX887_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAX1257147.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="JX887_001144"
     CDS             22688..23425
                     /locus_tag="JX887_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAX1257148.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="JX887_001145"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="JX887_001145"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAX1257149.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="JX887_001146"
     CDS             23989..24621
                     /locus_tag="JX887_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAX1257150.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="JX887_001147"
     CDS             24706..25353
                     /locus_tag="JX887_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1257151.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="JX887_001148"
     CDS             25358..26341
                     /locus_tag="JX887_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAX1257152.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
BASE COUNT         8062 a         5571 c         4464 g         8257 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttaccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatc
//
LOCUS       DADGHT010000030        26160 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.030, whole genome shotgun sequence.
ACCESSION   DADGHT010000030 DADGHT010000000
VERSION     DADGHT010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.030"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(62..1093)
                     /gene="queA"
                     /locus_tag="JX887_001149"
     CDS             complement(62..1093)
                     /gene="queA"
                     /locus_tag="JX887_001149"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAX1257153.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1286..2461
                     /locus_tag="JX887_001150"
     CDS             1286..2461
                     /locus_tag="JX887_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HAX1257154.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2465..3106
                     /locus_tag="JX887_001151"
     CDS             2465..3106
                     /locus_tag="JX887_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1257155.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3103..4020
                     /locus_tag="JX887_001152"
     CDS             3103..4020
                     /locus_tag="JX887_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1257156.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4017..4688
                     /locus_tag="JX887_001153"
     CDS             4017..4688
                     /locus_tag="JX887_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1257157.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5229..5717)
                     /locus_tag="JX887_001154"
     CDS             complement(5229..5717)
                     /locus_tag="JX887_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAX1257158.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5918..6184)
                     /locus_tag="JX887_001155"
     CDS             complement(5918..6184)
                     /locus_tag="JX887_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAX1257159.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6184..6447)
                     /locus_tag="JX887_001156"
     CDS             complement(6184..6447)
                     /locus_tag="JX887_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAX1257160.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(6440..6712)
                     /locus_tag="JX887_001157"
     CDS             complement(6440..6712)
                     /locus_tag="JX887_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257161.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            6923..7108
                     /locus_tag="JX887_001158"
     CDS             6923..7108
                     /locus_tag="JX887_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1257162.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(7250..9073)
                     /locus_tag="JX887_001159"
     CDS             complement(7250..9073)
                     /locus_tag="JX887_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAX1257163.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9671..12376)
                     /locus_tag="JX887_001160"
     CDS             complement(9671..12376)
                     /locus_tag="JX887_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAX1257164.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12682..13629)
                     /locus_tag="JX887_001161"
     CDS             complement(12682..13629)
                     /locus_tag="JX887_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAX1257165.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13819..14088
                     /gene="rpsN"
                     /locus_tag="JX887_001162"
     CDS             13819..14088
                     /gene="rpsN"
                     /locus_tag="JX887_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAX1257166.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14264..14626)
                     /locus_tag="JX887_001163"
     CDS             complement(14264..14626)
                     /locus_tag="JX887_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAX1257167.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14637..15758)
                     /locus_tag="JX887_001164"
     CDS             complement(14637..15758)
                     /locus_tag="JX887_001164"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAX1257168.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15774..16124)
                     /locus_tag="JX887_001165"
     CDS             complement(15774..16124)
                     /locus_tag="JX887_001165"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAX1257169.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16254..17765)
                     /locus_tag="JX887_001166"
     CDS             complement(16254..17765)
                     /locus_tag="JX887_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAX1257170.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18087..19439)
                     /locus_tag="JX887_001167"
     CDS             complement(18087..19439)
                     /locus_tag="JX887_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAX1257171.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19592..20668)
                     /locus_tag="JX887_001168"
     CDS             complement(19592..20668)
                     /locus_tag="JX887_001168"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAX1257172.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20864..22609
                     /locus_tag="JX887_001169"
     CDS             20864..22609
                     /locus_tag="JX887_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAX1257173.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22889..23326)
                     /locus_tag="JX887_001170"
     CDS             complement(22889..23326)
                     /locus_tag="JX887_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAX1257174.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23310..24683)
                     /locus_tag="JX887_001171"
     CDS             complement(23310..24683)
                     /locus_tag="JX887_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257175.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25005..25493)
                     /locus_tag="JX887_001172"
     CDS             complement(25005..25493)
                     /locus_tag="JX887_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1257176.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25515..26117)
                     /locus_tag="JX887_001173"
     CDS             complement(25515..26117)
                     /locus_tag="JX887_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAX1257177.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7504 a         5561 c         4837 g         8258 t
ORIGIN      
        1 ctttgtcata aaatctttgt aaagcttttt tgttattcaa aactagcggc ttttcataac
       61 cttatttcac gaacatcgca tctccaaaac taaagaaacg atagcgctct tcaatcgcat
      121 gctggtaagc agataaagtc aattctcttc ctgcaaaggc actaactaac atgactaaag
      181 tcgattttgg caaatggaaa ttagttgaga aagcttctac cactttgaat tcatagccag
      241 gcgtaatgaa aatatcagtc catccgctgt ctgctttgat ttctccatta aatttcgttc
      301 caatcgtttc taatgttcga attgaagttg ttccgacagc cacgattttc ccgccatttt
      361 tacgtacttg gttcaatcgc tcagccgctt cttccgtcaa acggtagaat tcactatgca
      421 tatggtgttc ttcaatttta tctacgctga caggtcggaa tgtacctaac cctacatgta
      481 gtgtcagata gactaattca acaccctttg cttcgatctc atcaagtaat tctttcgtaa
      541 aatgcaatcc agctgttggc gctgcagcag aaccattttc tttcgcatag acagtttgat
      601 agcgatctgg gtcttccaga cgttctttga tatatggagg caatggcatt tctcccaatg
      661 attcaagaat ctctagaaaa attccttcat actcaaagtc aatgatccgt ccgccgtgtt
      721 ccaattcttc tttcactact gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa
      781 ctttggcacg tttcgcaggt ttgatcaatg tctcccacgt atctccttgt gtattcgtta
      841 gaagaaggac ttctaaatgc gcaccagtat ctggtttttc tccatataaa cgagcaggca
      901 gaactcgtgt attattcata actagcgcat caccaggctg taactcttca atgatttcat
      961 ggaaatgttt atcttccatc tctccagttt tccgatccaa aacaagtaaa cgagaatgat
     1021 cgcggtcttt taatggtgtt tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt
     1081 ctgttgttaa catatcgtca ctcactttct atcatgtgct tcatcattct atcatgtttt
     1141 tcgttctgtt ggcaaaatca gcactttttc acttctattt tttgttttcc taaataaaaa
     1201 aactacccta tttgtatttt ttcattgttt taggcatact agtaatagat agttcttcat
     1261 tgaaaataga aaaagaggtg gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa
     1321 aggtggaaaa gtcgctgtag aggacgtcaa tctttcattt gaaaagggtg agttcatttg
     1381 ttttatcggt acgagcggaa gcggaaaaac gacgacgatg cggatgatca accgaatgac
     1441 tgatccaaca caagggaaaa ttttgattga tggaaaatcc atccaagaaa ttgatccagt
     1501 ggaattgcga cgtcagatcg gctatgttat ccaaagtatt ggattgatgc ctcacatgac
     1561 gatccgtgaa aatatcactc ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa
     1621 taaaacagct gaaaaaatga ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta
     1681 cccacatgaa ttatctggtg gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc
     1741 gaatcaagat atcatcttga tggacgagcc attcggtgcg cttgatccaa tcactcgtga
     1801 ttccttgcaa gaccttgtca aagatttaca agagcgtttg ggaaaaacga tcgtatttgt
     1861 aacccatgac atggatgaag cgattaaact agcaagccgt atcgccatca tgagtgaagg
     1921 ccgtgtgatc caatttgata caccagaaaa tattttacgt catcctgcaa acgatttcgt
     1981 agaagagttg attggagaag atcgcctact acaagccaag ccaaatgcga caagagtcgg
     2041 cgaagttatg ctaaatacag caatcacgat tacaccggaa aaatcattac aagaagcaat
     2101 caaactgatg agggaaaaac gtgtagatac gttgttagtt accgataatt cgaatgtatt
     2161 aaaaggattt atcgatgtag aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg
     2221 cgacattttg aataaacatg ttttttacgt aaaagaatcc gcctatcttc gtgatacctt
     2281 gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc gttgatgaac agaacaaagt
     2341 cgtaggtatc ctgactcgtg catcattagt ggatatcgtc tacgatgtga tttggggaga
     2401 agatcccgca actactgatg ttgcagagtc agctactcct gaagaatcta aggaggtctg
     2461 acctatgcag cagttttttc atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca
     2521 tctttatatt tcaggacttg ctttgatcat tggtatcatc attgctgtac cgcttggtgt
     2581 cttactgaca cgttttccaa aagctgccac gattgtgatt ggcttaacca gtgccttgca
     2641 gacaatccct tctcttgctt tattggcatt gatgatcccg ctatttggcg taggtaaatt
     2701 acctgcgatt atcgcactct ttatttattc attattgccg attttacgta atacgtacat
     2761 tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca aaaggcatgg ggatgactga
     2821 gttccaatcc attttttccg ttgaattgcc cattgctatg ccaacgatca tggctggtat
     2881 tcgtttagct gccgtttacg tgattgcatg ggctacactt gcctcttata tcggcgctgg
     2941 tggtttaggc gatttgattt ttagtggact gaataattac caaccagatc tcattttggc
     3001 aggtacgatc cctgtaacaa ttttagcact attggctgat tggcttctag gtctcttgga
     3061 acaccggctg acaccgatcg cacttagaga ggagaatgaa gaatgaaacg tatactaaaa
     3121 atgaccatgg ttcttttctc tcttcttata cttgcgagtt gttccttccc tggtcttgcc
     3181 agcaatacag atgaagacac catttcgatc acaggtggaa tcacttcaga agcacagatc
     3241 ttagcaagtc tagttgccgg aatggttgaa cattatacag ataaaaatac cgcaatcatc
     3301 aacaatctgg ctactacaac tatcaaccat caagcgatga tgaacggaga tgcttcaatt
     3361 tcagcggctc gctacacagg aacagattta acgactacat tgaaccttcc tcctgaaaaa
     3421 gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg agaaaagata cggtcaaacg
     3481 tggttcccgt cctatggttt tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca
     3541 caaaaatacc atctatctaa agtcagcgat ctgaaaaatg tagcggatga attagtagct
     3601 ggtgtagata cttcttggat caatcgtaaa ggagacggtt atgacggctt ccaagaaact
     3661 tatggcttct ccttcaattc gatattacct atgcagattg gacttgttta tgacgcagtc
     3721 gaagcaggaa aaatggatat tgttcttggc tactctacgg atggacggat cgccagttat
     3781 gatctagtca tgttggaaga tgatcgtcaa ttcttcccac catatgatgc tgctccagtt
     3841 gtagacaaca agatattagc tgatacgcct catttaaaag aagccttaaa taagttaggt
     3901 cataccatca gtacggaaaa aatgcaggaa ttgaactacg aagcagataa taatctagtg
     3961 gaaccatcag tagtagcaca acgtttctta caagaaaacc actattttga agggaagtga
     4021 agcaattgga taaaatgaat gtctttcaac aatttttcta ttatttccag gaaaatggct
     4081 cctatatctt tgcacaattt atccgtcact tcctgatttc tatctatggt gtcctctttg
     4141 cagcagttgt cgggattccg gttgggatca tgatttctag gagacgtaaa ttagcaaact
     4201 gggtgattcg tttggcgaat atcatccaga cgatcccttc tctagccatg atctccattt
     4261 taatcattgg attaggcctg ggagtcaatg tcgtgattgt tactgtattt ttgtattccc
     4321 tcttaccgat catcaagaat acgtataccg ggatgatcca agtagacaaa aacatccttg
     4381 atgtcggcaa aggcatgggg atgactgcta gacaacgact attcatggta gagttaccac
     4441 tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt agttgttgcc atcgggataa
     4501 ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga tatcattatc cgaggaacca
     4561 atgcaacaga gggcacatcg attattttag caggtgcatt gccaactgca ttaatggcga
     4621 tcatcacgga ctggctttta ggtattttgg aaagacggct agatccagcc agccgtacat
     4681 cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct
     4741 tttttagttc tgtcattttt aaggcaataa tccactctga ttcttccctc cttatgggca
     4801 aagagttgct tttcttagct atttatccat tccgtatact ccaacttcat actgccaacg
     4861 ggttcatatc tgcatccacc gactaagttt ttttcttatc cgctaaggca ttttgccaat
     4921 ccattttccc atcactcgtc atggaattca taccacatga tctctaaata ctcgtctgct
     4981 tgttctttga attgggcatc aattcttaca tcctttggcg tggctttcat ttaagccttt
     5041 tccatcagtc ctcgattgtt cgatgccttc agctgcatca tcaaaactgg tgactgccgt
     5101 atcggtaact tcgatcatct tttatacaat caggaacttg ccatcctcat ccttggctaa
     5161 aaacatatct agccattcca gcttctcgcc atgggaggtt tgcggttcct aaaaccggta
     5221 cacgattctt atggactgca tccgtcgcaa ctagacttgg cgatacgatg atccttcacc
     5281 agaagagcac ccccgtaaac caattgatcg atatattgcc aataagaaaa gacattggcg
     5341 taaaagatat cgatccctcg tgatgcattg ccgttgatac tgctattcat ggccgaaagc
     5401 gccacgactt taacttcttc cgtttgagtg acattcatgt tcggcaatgt cgctttggat
     5461 acccgctctg ctaaaggaac gacactggta ttgtatttcg tatctgtatc ttttccaaaa
     5521 gaccatgcca acgaatcctc tgggaaccaa taagacgact ccggttgatt gtccattgct
     5581 tttttcaaca tacttttggc tgtttctcga taaacgacat ttccaattgt cttcgcctca
     5641 ctttggcgat aatcgatggt cgttgccact gccaacacta acaacgatgc tccaatttta
     5701 ctgattttcc ttgtcacact tcttcctcct tgttttacat aaacccgtca acattccatt
     5761 cctaaactca aacaatgacc cttcaaaggt ggagatatag gaacaaatta aagaaatcat
     5821 gcaataaatc caagaaggtt ggttttagaa caaaaaaaga gtctcctttt tggggagact
     5881 ctttgttaac tatctaaaaa ggttggctct tctcacttca ctcataatgt gtccaggcag
     5941 aataaatttc tacaacttta ttttcctcat caactttgta aaccactcga tgctgtctat
     6001 tcagcctgcg tgagtatctg ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg
     6061 gcatatatgg atcttccttc aatgtctgaa tcacttcttc aaattgtttc tttaaattcg
     6121 tttgcttgat ttttcttaaa tccactttcg cagagttttt gattgcgact gtatagttac
     6181 tcatcaaaga gcttcccaat caatatcatc gatattcgta aagctactgt cgtctttttc
     6241 gcggtctcgt actttatcta aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc
     6301 tctccagtct tccagcccaa tcaatacagc attgtttcca ctacgatcac taataatctc
     6361 gatttcagta tgattttcat ttacctcttt caataactga taaaaatttt tacgagcagt
     6421 gctaggattc atcgttgtat tagccattgt ctctcctcct ttttctgata taattatagc
     6481 gtacttgatt aagtacgtca aaaaaataca ataaagcact taaattcagc aaacttttcc
     6541 tcttttttac atagagaaaa agaccccttt ttagggagga tctttgtcca cgctcacttc
     6601 ttactccttt acgactagcg gtagccaaac gtaaagtaat tggtaacaac gtatcatctt
     6661 tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca acaccaatac acgaaggttc
     6721 ctcgttgcag tgtgacttga ttgatatctt gaataacctg aggatacgca cgaaagattt
     6781 gtaacggtta ttcaaaactg attttggccg tcaagtcttc tactgcctca aaaatgattg
     6841 cctctttcgt ctcctgtcat tcatgttcac tatcgatttg atacttgctt agaccgttgg
     6901 gtttgtgaat caccaattaa aaatggcact gagttatggt aacaaaaaat ggtcacttga
     6961 cgaggctgag attcctactt atgaagacac atggcactta agagtcgagg taaaggaaga
     7021 agctgaaaat ataggaggct gtacattatt tggcaaagga ttcggaaatt atgatcaaga
     7081 catcaaaatc aaaatgtttt acagctaaat aggaagaata ataacatttc atacgctgtt
     7141 cccatcttta atggcttata gagggcacct ttagctgaga ataagacaaa acagaccctc
     7201 tagcttcaat taagagctag agggtctgtt tttgatttta aaacttggtt tatttcttca
     7261 aatggtagct ataggtgctg acaacgatat tttcacgcca agacaatcgc aatcttaacc
     7321 gcaaacttgt ttggttatgg agaatattct gccagcgtct gtttggtaca aattgaggaa
     7381 tcaacacagt agttgtatag ttttgtttcg ctgcattttt acttacgata tctacataac
     7441 ggataattgg attttcaatc gagcgataag aagagtggac gattgaaaaa cggacatctg
     7501 ggaaatgctt tttaaattct gcttcgattt ctttttcttt ttcgacatct tcgtctagcg
     7561 aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc gtaattcaac gcaccgatat
     7621 ttacccgtgt cacattcccg actaatacaa gaacggtatt cccgtcataa tcatgtagtt
     7681 ttgcatcatt ttctaaacga agctgttctg ctactttttt ataatgatca tggatcttat
     7741 aaaaaatgaa cataacgatt ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat
     7801 agacaaacaa aatcgcaatg attgcatatg agatgaacgc acccgtaata ttggcaatcg
     7861 atttgcttaa ccatcttttt ccttcttttt tccatttgac gaccatccct gtttgagata
     7921 aagcaaatgg aatgaacacg ccgatagagt ataacggaat caagcgttct gttgagccat
     7981 ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt gataatccca ttggaatagc
     8041 ctagtcgatc cccacgatct tgatacatgt gaggcatgaa tttatctttt gccagattgt
     8101 atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg
     8161 tagcaaattg aaggacgtaa tacaaaatac catgtccaaa gacagcttta ccaatttgag
     8221 acaaaacagt gacttctttt tcaggaacga tcccatacca atagttgata aatgtgatcc
     8281 ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg
     8341 ctcttggctt cttaaagaat ggtacagcat tactaatcgc ctccacccca gttaaagagg
     8401 aagaaccaga agaaaatgct cgtaaaatca aagcgataga aacacccggc acagccgctc
     8461 ctggaagtgc agtagcttgc aatggcacag cacctgtcac gatattatat aaaccaacaa
     8521 cgatcagtaa cgagatcaca aggataaatg tgtacaccgg aaataatagg aacgatgcag
     8581 attccctcag cccacgaaga ttcagcatca tcagtagcaa aacgattgtc acagaaatag
     8641 cgacttgatg accgtagagt gctggcaccg ctgatgtgat cgcttcagca cctgctgaga
     8701 cagatactgc tactgtcaac atgtagtcga tcaataaaga gccaccggaa atcaagccag
     8761 cattctttcc aagattctca ctgctgacga catatgctcc cccgccatga ggataagcat
     8821 ggatgatttg acgatatgat agcgttaatg aaatcaataa aataataaca aaagcggcaa
     8881 tgggtagcga ataccagatg gctgcagcag acaaagcgac taaaacgaca acgatttgtt
     8941 ccgtaccata tgcaatagat gataacgcat cagacgacaa taatgccaaa gcagcaaatc
     9001 gggttaattt gtgctcatca ttttcagcag attttaaagg cttacctact aacaaccttt
     9061 ttaagtaatc caatttctaa actcctttac acacaatttt acttcaagtt ttatagtcga
     9121 aaatttatag taaacaagat gttatagtac gctcactgac cttaaaagtc aataaacttt
     9181 aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct ttttcaaacg ctttaataca
     9241 gcaaaaatct aacatttttt tatgggcttt ttctttgaat tctataataa aaggatagaa
     9301 cttgacttag aaaatcaagt tctatccttt ttgatatctt aacttttgga agagagatgt
     9361 aaggctgctt tctacccatc attcttacta ctcgaagcat agcgcagttg tcacaacctc
     9421 ttgataaacg gtgtttaaaa gcttgcatct gcggtaataa gcccaaccaa attaaaaaca
     9481 taagaagctg tttttatttg gtcgttctta ttacttgatg cagagcagct tttttacaac
     9541 ctcttggtac acggtgttca atcagctgac cctcggtatt agctcaaaaa aacggcaaaa
     9601 tatgaggaac tatttttcca tttttttctc taatactcag gtcaaaacac tgatttcaca
     9661 acctcttttt ttaatgaaaa atatggctct catgcgccgc ttctttgaat ttcgtcattt
     9721 tttcttcgat gaacggatag attgccgttc ctacgattcc aaagacaaca aacaaaccga
     9781 tcatgatcca gattgctttc gtagcatttg gccaataaat tcctcctgca gattcccgta
     9841 acaagtttac cgcatgagta aatggcaaga acggattgat catttggaag aatttccctg
     9901 agacttggat cggatagttc ccgcctccgc cagagatcga cagtactaag atgataatag
     9961 cgatcccttt accgacatta tcgaataatg cagccaagac atagacgatc atcatgaacg
    10021 ctaaggcgat caagacagca aatgacacgc tgtagaccgg attttggaca tctactccta
    10081 gtaagaaaat attccctaat gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg
    10141 tcagcatacg agcaacgaat tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta
    10201 aatagtattc tgtcgtagca acacttgaaa gaagaacagc gccgacccac agacatagtg
    10261 cagtataaaa cggggtgcta gctgaaccgt tatttgcgat tggataaagc gcattggttt
    10321 gtagctcaac aggttgtgta aagaagtcac tttcttttgt tgcgtctagt ttcaataatt
    10381 tgatgacttc gcctagatcg acttcttgtt cgccttttcg gatcgcgtct gctgcttttt
    10441 ggataccagc tttgatattt ggccagtcat tgttgatcaa gtccgcagca gcgttcacag
    10501 ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa tgtaccggtg atttcatttt
    10561 ttagtgctgg ccaatcattt tggataaaat cagcggccaa tcctaatttt tgctgaatga
    10621 tcggtaattc attgttgtat aggtctgccc cttcattgat gccattgacg atggtatcca
    10681 tatttccatt cagcattgta ttggcatcat ggatttcttg tccaattgca ggcatttctt
    10741 tttgatattt ttctaaaatt gccactgcat tcgttacagt tgctttcgtt gagctgagaa
    10801 gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat
    10861 cgatgacttg gtctagtaga gaagtgacag tggaactgat ttgacctgta ttgataccag
    10921 caatgatgcc attgatatta ttaacaacgg catcaatttg atctagcaat tcatcaatag
    10981 ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga taggcggttt tgcagattgc
    11041 ttagcaaggg ttttaattga tttagctgat caataattgg ctgtaatttc gtatttccag
    11101 cacttgtttg caatttagtc aggaactcga ccagtttatc gattgcattt tgttgttgag
    11161 atattccgtc aataaagccg ttcaatacat tgctgatgtt tttcttttca tcatcagtca
    11221 gcttaccatc ttcaatagct gttcttacag tatctattaa cgaacctgtc gttgttgcca
    11281 cttgtccaat tgacttcaat gtaacatcta cactgtttgt gatgcttggt atcgcatctt
    11341 tcagctgaga ggcacctgat tttgtttggt ttgctagatc acttgcctga ttttctaaat
    11401 ttttcacatc tggcaagata tcttgtactt gttggatgat cgtcaagcct tgttttgctt
    11461 catcgattcc ttggttcatt gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta
    11521 gttgcttacc ggcattttgg atctctggga ttttttcttg caaatcaagg atgatttttg
    11581 cttgatcttt caactcaggc attttgtcat tcaatgcaac gactttttca cccatctcat
    11641 ctactttagg gatgtaatcc acgaattcat ttgctttatt cagtttttcc ttgatttcag
    11701 gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt
    11761 catctgttga taaaatcata tctttaactt tattgatact tactaggttc gtatcgatgt
    11821 cgtaacctat ctcattgaat actttcaata aagtcgaact ggctgttttg ataaattcat
    11881 ttgtgatttg cgattggatc gaacttgctc ctttatcggt gattttcggt gcaatcgcat
    11941 tgattttttc atttaccgta tattcgattt ttggtttctt gatatcacca ctagtaaaac
    12001 tcagcagatc ttctgagaaa tcctttggca agtaaatacc tgcgtaatac tttccggaac
    12061 ggactccgtc ttctaattgt tcttttgaat caacgaattg ccatcctaat tgtttatttt
    12121 tatgaagcga ttcgatgact tgctccccaa tggccacttc tttaccttga aactctgctg
    12181 gcttgtctgc actgtaaaca gcaattggca gctctccagt atttccatat ggatcccata
    12241 atgctttgat gttaaaccac gcatatagcg aagggatgat catgatcgcg atgatcagaa
    12301 gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag caaatataat cgaagcgtat
    12361 ttttgattga ctgcatagtt ctcccccttc ttcttttttc agctgaatta ctttaccatg
    12421 tatttcatac ttttttcaat cggctttttt caaaaaagtc gaatttttgg acatatcacg
    12481 gcaattgtct cattgtaatc tcttacatat tgagaaataa ttaaggatta cagcctttac
    12541 tttatcatga aataaaaggg aaagataatt ttatgccaaa gtttttatct attatacgta
    12601 tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac aaaaatgttt cagctttttt
    12661 cgttttttat tcctgtattt cttatttttc gaatgacagg atgattttcc cagcaggagg
    12721 atgtccttca actagctgat gtgcttggat gacatgctta agtgaagcag acagattcat
    12781 tgaaataaaa acatgaaagg ctcctttttg gtaggctttg attatgccag caaaggcttc
    12841 tgcatctaga tattcctttc ttggaacaaa cgattcataa aagccttcct ttttttgccg
    12901 caaatctaga tctgggaggt catttaatgc aacatacctg ccgcctggtt tcatgatctg
    12961 gatgccggtt tctcctttga tacttccttt cgtcgcatcg attacaaggt ctgcctgatc
    13021 agcaaattgc agacctggat ttgttttatc ataagcagca aatgctgaag ctcctaattt
    13081 ttttaccttt tcctcatttt tactggatgc actggttaag attcggattc ccttttcatg
    13141 gagaagctgg atcagacttg acccgaccgc acctgatgct cctagtatca ttacagtatc
    13201 tgtcggctgg atttccgtca aatggttgat tagattataa gccgtaattc ctggcgtgac
    13261 cattccggct gcttcttccc aactcatttt atctggaatt tttgctactt ttgctgatgg
    13321 caacacgact tcttctccgt aagtcccgcc gactgcatgg acagctactc gatcacctac
    13381 atgaacagtt gtgacatctg aaccaatctc tgtcacaata ccagcgccat cattacctgg
    13441 tacataaggg aatttcaatg ttcgtatctc tttcatttct cctaaacgca aggcaacatc
    13501 ataaggattc acactgaatg cttttatttc tacacgaaca tgtccagaac cgacttctct
    13561 gggatgagca tcgatttctt caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa
    13621 tcttcgcatg gtcaccatct ccctttttct ttaagtttac gtttatgcct ttattttgac
    13681 aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca aaatagttgt cttttttcgc
    13741 gtaacgtgtt aaattattta tctaaaagcg taaagattac gatttacgct aataaaaaat
    13801 aattggagga atttgttgat ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa
    13861 gaaacgattg aacgctatgc tgctttacgc caggaattaa aagcgcaaaa agattacgaa
    13921 ggcttgcgta aacttccttt agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc
    13981 gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa
    14041 ttagcacata aaggtttgat tccaggagta aaaaaagcca gctggtaatc caagtctggc
    14101 tgtaatgtaa aggaggaggg cgcatggacc actccttgga tcatcaaaaa agatacgttc
    14161 gcttcttcta gcagaaatgc tggtactaga agcagacgta tcttttttta cgcacagctg
    14221 gtcctttttt atatgtaaag gctgcatggt tacttcgcta tatttattta gtaacaggag
    14281 tcagtgcttc gatacccaca ctaattttca atgctcggtc aacttctgcc ataatgggtc
    14341 gatccaaatg gcagaccttt tctttcaatc ttgatttatc gatcgttctg atctgctcca
    14401 acaggataac ggagtctctt tctattcctg ttccagtagc tttgatccca atgtgagtcg
    14461 gaagcttagg tttagccatt tttgccgtta tggccgcaac aatgatcgtc gggctaaaat
    14521 ggttacctag attattttga ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca
    14581 cgactggaga aagatcagca aaataaatat ctcctctttt taccatagga tcctccttat
    14641 tcttgatatt ctcttggtat ccgctgtcct aatccgcaag ccacttcata gtggatcgta
    14701 cctaattgat ctgctatatc ctgcatagtg atttctttgt ctgcattttt gccgataagc
    14761 gtcacttttg ttccgacagg aaattcttga ggcaatcgga tcatcagttg atccatacat
    14821 acacgcccaa tcgtttcaca gtagttccct tctaccaata gagaaaaacc ctgcatcttt
    14881 cgtggccagc catctgcata accgatcggt atcgttccga tccactctgc ttcaggagtg
    14941 atatatgttt ctccatagcc gattccttca cctgctggga gttttttgac ttgaatcaat
    15001 tcagaaacca gctcaagtgc tggctgcaat ggataaactt ccggtagtgc gtgcccagag
    15061 ggattaagtc cgtacattgc tactccataa cgaatcatat tgccgattgt ttcatcatgc
    15121 cataaagccg ttgcactatt gctgacatgt acatatcgag gaagttcggg aagttttttc
    15181 agcacttcta taaagcgttc tttttgcaga ttccaatatg tatcatctgc ctgatctgct
    15241 gtagaaaaat gggtaaataa accttcccat tctaatacac gactttcttt gatgaatgca
    15301 gctgcctctt ttacttcttc aggtgtacaa aatccgatac gacccatccc agtgtctgct
    15361 tttagatgaa tcgaaagagg cgtctctagc ttacttttct ctaaaacagc agctgctgct
    15421 tgcaaccatt cccgtgtacc tgcagttact gataaatcat gagcaacagc tacagtcagt
    15481 gcgtcgtaag gaaccatatt caagataagg atgggctgag taaatccagc ttctctcaac
    15541 tcgactcctt catctaaatt tgaaacacaa aagcccgaag ctccacctgc aactgctgcc
    15601 tcagctgttt caatagctcc atgaccgtat ccgttcgctt ttactactgc aaacaattct
    15661 tttccttgcg gaagtcttgc aacttcattt gctacatttt cagttatagc ttttttatgt
    15721 atcactgctt tcgttgggcg gtgccaagcg acaaccatcg tttttccttc tttctagtct
    15781 tccaaaataa tttgtgcaaa agctgtttca tttgtatgag taatactgac ccatacattg
    15841 ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt cattttttaa aatctcgaca
    15901 tcttgaaagg taacttttcc gatcccagtt ccccaagctt tagagaaagc ctctttgcaa
    15961 gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag gcaaggactg gaatagtttc
    16021 atttcatcag aggtcaagat tcgtgcaatg aattttggtt tttcttcgat cagccgagtg
    16081 atcctaggaa gttcgactgc atcgatccca attcctttta tcatatgctt ttctcttttc
    16141 aataaattta gaacactctc attctaccaa attataacca ttttgccaca aataagtcca
    16201 caaataacaa aaatgaaagt ttctcttaaa aaagagaaac tttcatttta tgtttaatcg
    16261 ttatttgaac ggattacaaa tccgcgtttt ttatcattgt gacgtttacc gccatctttt
    16321 tggctgttat tatttttgct ataaccgcct tttgatttgt ttccacgata attaccgccg
    16381 tcacgacgat tacggttgtt tccgccacca cgtttgccat ttttattgta tccttttttc
    16441 tgcattggca atgggcgttc tggtgtgatc ttcactggca ctgcatcagc tggatctttt
    16501 gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag aatattcttc taataattta
    16561 tctgctgttt gcaggtattt atctagacca ttttctgcaa gttttgtttc gatttgttca
    16621 actgcagcac ctaattgacc tttgaatgct tctttttcgg ttggtggacg taaagtcgtc
    16681 atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg
    16741 aaagtcacag acataccgcc ttttccggca cggcctgtac gtccgatacg gtgaacgtag
    16801 ctttctggat cttgagggat atcatagttg tacacatgag tgacacctga aatatctaat
    16861 ccacgtgcag caacgtctgt cgctacaagg atatctaaat gaccgctctt aaatgaacgc
    16921 aatacgctca ttcgtttttg ttgagacaaa tcgccatgga ttccttctgc acggtaaccg
    16981 cgtgcttcta atccgcgtgc caattcgtct acacggcgtt ttgtacgtcc gaagacgatt
    17041 gttaattcag gtgtttgaac atcaaacaag cgagtcatga tatcgaattt ttcgtattct
    17101 tttgcgcgga catagtattg atcgatcaag tcagctgtca tttctttcgc tttgatcttc
    17161 acatgatgtg gatttttcat gaatttaacg ccaatattct tgatagctgg cggcatcgtt
    17221 gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg aaatgatttt ttcgatatct
    17281 tccaagaagc ccatattcaa catttcatct gcttcatcca aaactaatgt ttgaacggtt
    17341 ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac gtcctggtgt acccacaacg
    17401 atatgtggac gatctttcaa gccacggatc tgacggccaa tatctgctcc gccgtaaacg
    17461 gcttgtacac gtactttttt gtcgcgccct aaacgatata attcttcttg tgtttggata
    17521 gctaattcac gtgttggtgc gataactaaa ccttgtaatt cgtgacgatc tggatcgatt
    17581 ttttctaaca ttggtaatcc aaatgcagct gttttccctg tacctgtctg tgcttgtcca
    17641 ataacgtctt ttccagctaa tgctagtgga atcgtttctg cttggatagg cgttgcttct
    17701 tcaaaaccag cgcgttcgac tgatttcaac aattctggtg ataattctag ttctttaaat
    17761 ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt agcttttttg ctaccccgtc
    17821 gatttgttcg gtcaaagtgt attgtttctt tttgacagtg gccacgcacg tttttatcca
    17881 ttcttagccc ctgtggcacc accgaaaaat cactttgcga agtttaggca ttagaaaagc
    17941 caaacgggtc gcgttcagct ttatcattat tatgacatct ggcttcaaca agttgtttct
    18001 atggcaaaac cagtccaatt tctcttcatc tttcggcaat aggttattct aacatagttt
    18061 ttcgttttct gcaagtttac agatttttat ttcatttgct gaagttgttc taccacttca
    18121 aataagccca tgctgttgct gccttttagc ataatactat ctgttgcttc aagattttgt
    18181 ttgatagcat caatcaattt attcttttct ttttccaaat agaacacagg tagttggggg
    18241 tatttttggt tcaattcttc ttttagtgca tgcatttgtt ccccataaag gaaaatcatg
    18301 gcgaatttct caggatcgat atgttcactc atttgcgcat gcatatttaa agactctttc
    18361 cctaattcca gcatatctgc taacacagcg attctgcgtc cttttgttgg cagattttta
    18421 aaagtatcta ataccagtcc catggctgtt ggatttgcat tgtagacatc gctcaaaata
    18481 gctgcaccat ttcctgccgt tagccattcg gttctgtttt gagtgataga aacatgggcg
    18541 agcccttggc gtatctcagg tatggacagt ccaaagaagc gcccgatcgt atacgcaatc
    18601 aaagcattcg ttacattata acttccaggc agcgggatcg taaatgtttc tccttctact
    18661 acaaaatcgg tttgtgcttt tccttttgct gtcacttccg catgaacatc gccatttcca
    18721 ataccgaatg ttgtgactgt ttgtactaat gttgccgtta aaggtgtcag caacggttca
    18781 tctgcgggca caacgagtaa tccgtctgat acaagtccgt cagtgatttc cattttggct
    18841 ttagcgattc cttctcgcga cccaagattt tctatgtgtg cttcaccgat cattgtgatt
    18901 gctgcagctt ttggttgagc cataagtgaa agttccgtga tttcattggc gtgatccatg
    18961 cccatttcca aaacgatctt ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga
    19021 ccaatattat tgttgtaatt tccttgcgtc ttatatgttt tgtatttttc agacaagaca
    19081 gacgcggtta gatctttcgt ggtggtttta ccattgcttc ctgtaattgc aacgacttct
    19141 gcgcctactt tttccaagta ataggttgcc aattgctgca tggctttcaa aggatctgct
    19201 acaggaataa ctggaaaatt ttttggagct tgttcaacag gcaagctcca aaatgaagca
    19261 gatgctccgt ttgtgatcgc ttgctggata aattcatgtc catctcgcgt accagcaaga
    19321 ggaacgaata aacttccttc ggttatcttc cggctgtcaa attcgacatt ggtaatcttt
    19381 gtcagtgcag agcattcgct gcccacggct tgtgcaattt cttgtattgt tagattcatt
    19441 gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg
    19501 actctcactt ccaagtaaat ttctctattc gtatttagaa gctagaatga acgcggttac
    19561 gcaatcactc cagcctcttc tttatttctc tttattcatt tttttcaaaa aaagattgac
    19621 gctgatggta tcgattcatt cctaactgga tcagttcttc aatcaaatca ccgtatttca
    19681 agcccatatt ttcccataag agtgggtaca tactgaactc cgtaaatcct ggcatagagt
    19741 ttaattcatt caggaataat tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc
    19801 cgcttccacc taacatcgtg taagctaact tcgcgtactc ttgcgctttt tgataaactt
    19861 cttctggcac ttcggctgga atctgcattt cgattttatt attgatatat tttgcttcat
    19921 aatcatagaa tgctacgtct tttacgactt caccaggcaa agtcgtccga acgtcttcat
    19981 ttcctaatac agcaacttcg atttcgcgcg cttcaattcc ttgttcaacg attgctcgag
    20041 aatcatactg ataggctgtt gctaaagcat tttgcagctc ttctcggttt tctgcttttg
    20101 taatgccgac actagaaccc atattcgccg gtttgacaaa catcggataa agcaaagaac
    20161 cttcacattg atcaaatact tttttaggat tttctttcca ttgattctta agtactggta
    20221 cataaggaac ttgcggcaca ccagcagctt gtaaaatata cttggtcatg attttatcca
    20281 tggcacatgc actggtcaat acgcctgcgc cgacataagg catattcaat gtctctaaga
    20341 agccttggat cgttccatct tccccgtttg gcccatgtaa aactggaaaa acgatggctc
    20401 cttcttcttt gatttcgccc ggattgatca cttttcctgt aaagccttcc tctgtctgtc
    20461 cacttgggtc ccatgaaaga tgcaagacat ctttgctggc aggtttttct gttagtaatg
    20521 gacctttgac ccattgtcct tcttttgtaa taaatacgag ttgaacttgg taataattat
    20581 aataaatggc atttaaaact gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc
    20641 gtccgccata tagtaaagta atcttcaaaa gattgtcctc ctgtattcta aatcgttcag
    20701 tgatttactc tcatatttta gcacaaaaca aaaataaacg aataacttat ttataaaaaa
    20761 acgagccagc ttctaaaaga acgagcgtca tttatttttt gtcagctaga ttatttgtcc
    20821 cgttttttat aaaaagttat gataaagaaa aggagggatg atgatggcgc aaacaaatcc
    20881 acgcagccgc ttggcagaaa tcattcgagt gttcatcaat tacaatgtag tgccaaactt
    20941 tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt gaagaactag gccccacctt
    21001 catcaagata ggacagatgc tttctgttcg agaagatttg ctttcttctg ccttcactca
    21061 aacattcaaa acattacaag atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac
    21121 gatcgaaaca gaactttctc tttcattatc agatatattc gatgattttt caaaatcgcc
    21181 ttttgcctct gcttctatgg ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt
    21241 agtcgttaag atccaacacc ctaacatcgc cgaagagatc cgacttgatc ttcaactatt
    21301 tgaacgagcg atccctttga tcaaatacat tcctgaaact agcgtagttg atctaaaagg
    21361 ggtactccaa gaagtaaaac gttccttgat caatgaaatg gacttcttaa aagaaagtca
    21421 aaatggcgaa caattctatc aaaagaacaa tggctggaaa gagatccgca gccccaagat
    21481 ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt
    21541 gaatcattta atgaacgccg aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa
    21601 gcagctgaaa caagaagttg caaagctttt agttgagaac tttatgaaac aggtgtttga
    21661 tgatggtttt ttccatgctg atcctcatcc agggaatctg ctattccatg tactaacaaa
    21721 agaagaacag acacaagcta gccgaaaaac tgaaacagtc catgaaaaag agttcggttc
    21781 ctttgctttt cgagcctcca cttctgcaga agaccctgtt gcgccatata ccatcaacta
    21841 catcgatttt ggtatgatgg ggcatctttc tgcaggactt aggcaaaaac tcacacaagc
    21901 cgttttagcg ctgtatacga aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg
    21961 tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa gaactgacaa gttttcttga
    22021 acagtattat gattctccta ttgatgaaat caacttgcaa gaagtattca cacatgtcgt
    22081 gacgatttgt catcaaaata atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc
    22141 atttgggaca ttagaagggg tgatccgcgt cctcgatcct gaagtttccc tcatggaagt
    22201 cgcttcgcct tttgctcaac attattttct cactcatctg gatgtagaag atacattgaa
    22261 acaaagcgga ttagacttat tggaagggat gaaggctgcg cctaagatcc ctcaacagct
    22321 ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa
    22381 gcaagacaaa ttattgagca ggatcgaaag tatgatcaat cggcttgttt tcggtatgat
    22441 tttagctgca ttgatcgtag ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc
    22501 agaggtcgtt tccttattag ggatatttac gtatgctatt gccgcattcg tcattatttt
    22561 tttggcaatc gatgcattga tccaaatgta taagaagagg aaaaagtaga aaaaggttgt
    22621 gacagaaaga atcagcttca agaaataaga aggggtttta cataaattgt ttctcaaatt
    22681 tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct gaaacaccga gaataaaaaa
    22741 tgtgaaaaag ctgttctgca cccagtaata agaacaatca aaaagggaac atggaacaca
    22801 tttatcctgt ttccctgttc cctttttgat gtattcgagc ataaataaaa taccttcgtt
    22861 acctactatc ttctgtactt ggtaaacctt agtcaattgc cttttttaac gcttgacgaa
    22921 aagacatatg atctttctcc gtaaagggtt ttggaccctt tgtccttatg ccagcttttc
    22981 ttaactttcc actatgataa cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt
    23041 cttttccaga gtgatggaac actcgcacac ccttcggcaa tacaagtgaa gctaaaccat
    23101 aatcttgcgt gatcaaaaag tcattcttct taaccatacc gacgatttta taatccgcac
    23161 tatcagctcc gcggtctacg tagacgattt ggacatgatt agcgtattct ttggtcgtat
    23221 aatggtccac actggtcacg ataaccacgt caagaccata ggattctcct aattttatga
    23281 catcttcttt tactggagaa ccatctccat caatgaatag cctcattctt tttcgccttc
    23341 ttccataaat gataaacagt tactaatccg ctcagtaaaa gaccaacatt gatccatttt
    23401 gccaagataa gcagttgtac actttctatc ggcactgatt catggttcag cgtgatcaat
    23461 aatagatgga ttggctctcc catttctttt gctaaaacaa acaaaagcgt catcaataaa
    23521 aactggtgga tcacactccc tttattttga gtagtatact tgacaacgat ccggcgatcc
    23581 attggaatag ctgtatcagt ttgataatat tccttattta gccagctgcc tgttactacg
    23641 tgccagaaac taagcagaaa gacacctatc gcaaaaccat ttggaatcaa gaggaccaat
    23701 aaagaagaac tcagtccaag caattgcata gccaatggag accatgttaa acgtttcaaa
    23761 atccatggtc cgactatttt tgctgcaatc aagcctgctg cataaggcaa atacataaaa
    23821 atcgaaagtt tttctaatcc gtacagtatg ccaacataaa aactgctaaa taaaaaaagg
    23881 aaattcccta gcattccatt tagaaaagta aacagattta gccagcttgg caacttccat
    23941 tccttcttct ggtgtcctaa aacaaacacg aacaagatga acagcagcaa gaaaccataa
    24001 atagcaagat caaaaagcct ttcatcgaat aacaatcggg catttctcaa aagaaacaat
    24061 aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag ctaccagatt tcttttgatg
    24121 tctttgaaat ccagttcgta acgcggataa tgactaaccg tatggtaggc catgacgtaa
    24181 aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct
    24241 tgatacagga gaaatagcca gatagctgca aataagtact ttttcccatc catattgata
    24301 aaaccttgcg tcttttcgtg aaaattgacc gtggtattag caggtacaag ccatgctgca
    24361 ctcagcccta gcaaaacact tgaaaaataa aataaaggaa aataaaatac gcctaatatt
    24421 ccaagcaatg aaccagcacc accaatcagc agagcgatca tcagcaacgt gtaactatct
    24481 agaccaaatc gtagactgtt gactaaaaat agtccagtca tccgaaaggc ataaaacagc
    24541 gtaaatggca aaatcgtcag ccaattatgc gagtctgtta gtcccaaaaa taaaagataa
    24601 ggaataaaaa taaccgtgtt acttaagata aagggcgttg tttgtgtaaa attacgccca
    24661 aatcgtttga gtttttcgaa catgacaatg gctccttaaa cagtcttata actaatctgc
    24721 tcttcgattt tagcattaaa ggggaaataa accaatttta cagaatatat tcttgtaaaa
    24781 aaaaatacag aaagaagcat aagcttcttt ctgcattttt acggtacttg attactcaag
    24841 cagacaagcc cttctccaca aaagtcttgc ccgacacccc tgcatccggc aggtgataaa
    24901 gatagaaatc aattatcctg tgcctccaaa atcaattagg agctctgtaa accagagtcc
    24961 ttctcgaccc gtcgcataaa tttactttaa cacagttcct atgtttatgc gagagctttt
    25021 ttcattttat aatcgaccat ttgaaatcct tgaccgatat ctgaaataag ttcttctgta
    25081 atctcaaatc cttcatgctt ataaacctcg attgcttgat gattcccctg attcactcgc
    25141 aaaaagatct ctctttcctt tgtttgcgca gcaagttctt cataccagcg aaaaactgaa
    25201 gaagtcaatc cttgaccacg tactttattt agcaaatata atttacttaa ataaattttt
    25261 ccatttatct cttcataagc agtgtaaccg acagtctttt cttcgctttt taataaaaag
    25321 taggacacac cttctgtcag ttctttttga atctgttttt ttgactgata agttttcagc
    25381 atgtaatcca cttgtttttg accaatgatc ggcacaaaag cttccggcca tacttcttgt
    25441 atgactgcca tcagctcatc cagttcattt tctgttactt ttattttttc catacaccca
    25501 cgtccttttt tacattataa atgaccttgc gcttgatgga ataaaaagag catgatcatg
    25561 ctatacacac ccaccgacca tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa
    25621 gataatttcg tcaaaccagc tactagacag atcaagtcgt ctggcgcaaa gggaagcagc
    25681 aaggtaacaa ctagtacttt tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat
    25741 ttctgatact tttttggcga taaaataagc tggacaaagg ctacgccata gtaacggaca
    25801 agcaaaaatc cgattgcttc cccaatcact aggccaatac aactatataa aagcccaaat
    25861 ccattgccaa acatcagcat gcccgctact gaggagatcc ctcccggcaa aataggaatg
    25921 atcacttgga tcacttgcaa cagaacaaat atcatcactg catacttgcc aaattgctgg
    25981 ataaacgctt gcaaagacgt gctcgatcga aaaatcccat gatgataagc ataaagaatc
    26041 aacacaaaga aaaaaaacag accaataatg ggcatgatct gaagacattt ttgtaaaact
    26101 gatccttttt tagacatcta tattccccac atcttttttc atttattaaa actgcctcct
//
LOCUS       DADGHT010000031        26101 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.031, whole genome shotgun sequence.
ACCESSION   DADGHT010000031 DADGHT010000000
VERSION     DADGHT010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26101
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.031"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(42..1168)
                     /locus_tag="JX887_001174"
     CDS             complement(join(42..940,940..1168))
                     /locus_tag="JX887_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAX1257178.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(1572..2354)
                     /locus_tag="JX887_001175"
     CDS             complement(1572..2354)
                     /locus_tag="JX887_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257179.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(2419..3255)
                     /locus_tag="JX887_001176"
     CDS             complement(2419..3255)
                     /locus_tag="JX887_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1257180.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(3273..4682)
                     /locus_tag="JX887_001177"
     CDS             complement(3273..4682)
                     /locus_tag="JX887_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1257181.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(4696..6519)
                     /locus_tag="JX887_001178"
     CDS             complement(4696..6519)
                     /locus_tag="JX887_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1257182.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(7362..7688)
                     /locus_tag="JX887_001179"
     CDS             complement(7362..7688)
                     /locus_tag="JX887_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257183.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(7734..8096)
                     /locus_tag="JX887_001180"
     CDS             complement(7734..8096)
                     /locus_tag="JX887_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HAX1257184.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(8133..8347)
                     /locus_tag="JX887_001181"
                     /pseudo
     CDS             complement(8133..8347)
                     /locus_tag="JX887_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            8475..8810
                     /locus_tag="JX887_001182"
     CDS             8475..8810
                     /locus_tag="JX887_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1257185.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(8886..10883)
                     /locus_tag="JX887_001183"
     CDS             complement(8886..10883)
                     /locus_tag="JX887_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257186.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(10981..11256)
                     /locus_tag="JX887_001184"
     CDS             complement(10981..11256)
                     /locus_tag="JX887_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1257187.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            11488..12222
                     /locus_tag="JX887_001185"
     CDS             11488..12222
                     /locus_tag="JX887_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1257188.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12261..13403
                     /locus_tag="JX887_001186"
     CDS             12261..13403
                     /locus_tag="JX887_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1257189.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(13498..14889)
                     /gene="sufB"
                     /locus_tag="JX887_001187"
     CDS             complement(13498..14889)
                     /gene="sufB"
                     /locus_tag="JX887_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAX1257190.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(14894..15364)
                     /locus_tag="JX887_001188"
     CDS             complement(14894..15364)
                     /locus_tag="JX887_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAX1257191.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(15351..16586)
                     /locus_tag="JX887_001189"
     CDS             complement(15351..16586)
                     /locus_tag="JX887_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAX1257192.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(16583..17869)
                     /gene="sufD"
                     /locus_tag="JX887_001190"
     CDS             complement(16583..17869)
                     /gene="sufD"
                     /locus_tag="JX887_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAX1257193.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(17882..18655)
                     /gene="sufC"
                     /locus_tag="JX887_001191"
     CDS             complement(17882..18655)
                     /gene="sufC"
                     /locus_tag="JX887_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAX1257194.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(18852..19700)
                     /locus_tag="JX887_001192"
     CDS             complement(18852..19700)
                     /locus_tag="JX887_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1257195.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(19724..20410)
                     /locus_tag="JX887_001193"
     CDS             complement(19724..20410)
                     /locus_tag="JX887_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1257196.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(20403..21437)
                     /locus_tag="JX887_001194"
     CDS             complement(20403..21437)
                     /locus_tag="JX887_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1257197.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            complement(21832..22170)
                     /locus_tag="JX887_001195"
     CDS             complement(21832..22170)
                     /locus_tag="JX887_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAX1257198.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(22172..22528)
                     /locus_tag="JX887_001196"
     CDS             complement(22172..22528)
                     /locus_tag="JX887_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAX1257199.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(22534..23721)
                     /locus_tag="JX887_001197"
     CDS             complement(22534..23721)
                     /locus_tag="JX887_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAX1257200.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(23912..24757)
                     /locus_tag="JX887_001198"
     CDS             complement(23912..24757)
                     /locus_tag="JX887_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1257201.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            24991..25956
                     /locus_tag="JX887_001199"
     CDS             24991..25956
                     /locus_tag="JX887_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAX1257202.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
BASE COUNT         7618 a         5443 c         4424 g         8616 t
ORIGIN      
        1 ggatttgagt caatatcttg gacacatttt agtagagacg gttaagccat tttttctttt
       61 gctaattctt caaattcctg tggggttaga tagtgaatcg agctatggat tcgatttcgg
      121 ttataaaatc cttcaatgta gctaaatagc gctcgatttg cttcttcaaa atctgagtag
      181 ctagtcgtgt agacttcttc ttttttcaat gaggcatgga aagattcgat tccagcatta
      241 tcataaggtg ttccttttct actataagaa tgccttattt tgttggtttt aagccattgt
      301 tccacttctc ttgctgtgta ttggctgccc aagtcagtgt gtagaatcat tccttctgga
      361 atgtgataat gtatttttgc tttattcaat gtttgaatga cacaatccac agtcattcgt
      421 tttgaaaatg tataactaat aatttttttc gtgtgtaaat ccatgattga agataagtaa
      481 caccaaccat ttttcttagt aggaatgtac gtaatgtcag ctgcccattt ctcacagatc
      541 gtttcagtag aaaagtcctg atttaagaga ttctcttttg aaatgatcgg tttattagac
      601 ctttgaggtc tatatttttt aactacaatc gaccttaaat ttaattgttt cattagcttt
      661 tggacatgtt taagagatac tgaaatccct tcttttaata aaacttgatg gatctttgtg
      721 gcaccatagc gttgtttatt cgtaaaaaaa attgttgaaa tcttcttttt caacttatta
      781 tttctgattt ctgtagctgt caacggttta ttcttataaa aataatagac acttctaggg
      841 atttctaata accgacataa caaagaaaca gtgtaatcct tacaccattt ttcaataaat
      901 tgaacaagcg aatttaggtt ttccgagaga atatggctgc ggcttttttt aagatttcaa
      961 gttcctcatt taaacgagca ttttcttttc tcagttcagc tacttctttt ccagtcagtc
     1021 ctgtggactg atcaggtaaa tataaattct tccatttgta aatcgttgct tcagataagc
     1081 catattcttt cgctaaccct cgaacagaac gtccagtttg attcagttca acaatcattt
     1141 gtttaaaatt ttcttcatat cgggtcataa aaattcatcc tctcgtagat aagtttaatt
     1201 tattcttgtc tctacgaaaa gctgtctaag atttgatact aacaccaagt tatctttaga
     1261 accatttcag atacatatga aacaattaca tatgattttt tcataaaaaa acagtactgt
     1321 ctagtagtat aaaatataca aatttcttaa aaattttttc actaaaatca ctacctgaaa
     1381 cagtctaaaa cacttatata tcaacgttta atgaaactat ctccgtttca tttcagatac
     1441 aaataaatat agtcgggctc caaatccgaa aaaaaatacc cccagtagct tatcctaagc
     1501 tactggagat gtataagtac ggtcatataa caacggggta gggtaaataa atgaaaaaga
     1561 tggaagaatc attattcaat aactttttta aatacttcgt tgtaatcagt tacctgtccg
     1621 ttcttaaata ccacagaata atcttttttc ccattttcaa gtaaccgaag tggaatgtct
     1681 ttaccaactt gctctgtcac tgcattactg atacctgtta gattagctaa taaatctgat
     1741 aaagattgag catctgtaga aatctctgta tcagtattta tcgtgattcc tttatcttca
     1801 tttacaagct tccaagtagg tggtatagct gtgtatgttt cgatgaatga atcaattctt
     1861 tcatctatcg tcttcccagt atctacttct gtctcattac tcttagatga atcgattctt
     1921 tcatccatcg tctgctccgt aactgcttct gtctcattat tctcaccgga aactctcttc
     1981 acacccaaac ttatatattg tccatcttta gtgtgcatag ttaaaattcc cacgctttta
     2041 ctaataaatt cactataacc agttctttca atagagactt caatgtattt cacactatca
     2101 tactcaaaag aaaaatagac atgtaaaagc attttgttgt ttacatctac ataataatcc
     2161 tttgactcta cttgagacct tcctatacgg aatacagctt tactgtctga tatctctata
     2221 ccagcatcct tattattaat ctgccaatct ccaagtagct cttctggcaa gctagtagtt
     2281 tcttgtgaac actttaccac ttcactggta gaggtcgaaa cattcacctc cgcactgtta
     2341 gaagaatttt ccaaggaatc aggagcctta gcacaaccaa caagtcttta tatattgtgc
     2401 agccgatatt ttcttcattc agtacaccct tgaaatatgc agtgttagat aaagcagttc
     2461 gtcctgattt gctgaggcac ccatctcttc ttgaacgtac tccttgattt tcaaggccgc
     2521 ccgatactct ttcggaaaac gctgcttcac tgaagccagc aaaaaatcat ccttctccgg
     2581 caactcttcc ttcttaatca ttcgggcaat aaaaaactgt aaatgcgtca caaatcttaa
     2641 gtaaagcatc gaatctttat caaccttttt ttcgggaaac agatatccta gcatagccaa
     2701 gatatccttt agtgctctta ccgagagcat ggtttcttcc atatttgctt gttcactttg
     2761 ggcatttaca atgtgaaacg caatgtttcc agcctcctct tctggcaact gaacattcat
     2821 ttttttgttg atcaattgga tagcatagca gccgatctca aattcttttg ggtaatactt
     2881 ttgaatttca atcagcaggc gattttgaaa aacaatgcct ttttgactgc gttcaatggc
     2941 atgcttcaag tgatcaacca aggtaaaaaa tagactttta ttcagcttaa agtcaaactt
     3001 ggcgttggca taatcgataa ttcgcttgac gcaaataatt agatcatccg gagcagcctc
     3061 aaacagttta atgtaatcct tttttagagc atcagaaagt gaatctaatt taaatacttt
     3121 ttggattttg tcagccggaa ccaaatcgcc tttctttagt tgaaatccaa tccctttccc
     3181 catcaaaatt acttctttgc cttgcttatc taagcaaaga attaaactgt tgtttaacgt
     3241 tttaattact ctcattagat tcaccgttct ctctaagcta agccatttct tgcgattact
     3301 ttttgatacc aaaagaagct ttcttttttt attcgtttta attctttaag attctcatcg
     3361 gttcggtcaa catatataaa accataacgc ttattgaagc cttgatgggt actaacaaca
     3421 tcaatcgctg accaaggtaa ataaccaaaa acatctacac catctgttaa agctgcttga
     3481 atagccagaa tatgtttggc tagataatca attcgatcct ggtcattaat tcgtctatct
     3541 tcctcaacta tgtcgggtgc cccatagcca ttttcagtaa ttaaaatagg taaatcatag
     3601 cgatcgtaca atttcctcaa tgttaatcgt agtccagtag ggtcaactac ccagccatat
     3661 ggcgttttat ctacataagg attttcagct gcccggtaga caccttcttc tcccaacatg
     3721 atctgttgat cccccgctct agcggaaaca tctgatccgt catttttgct ggcagcgatg
     3781 gtggcagttg aataataatt aatcgcaata aaatcgggtt taccggagga taaaattgcc
     3841 tgatcctctg cctcaatttt aggatataat ccacgatcat tcaaatagtt ttcaaacaaa
     3901 taattgtatt ttccccgaac tgctacatct aagaaagacc agcctctcaa tgtttcccaa
     3961 ttatgggctg caattgcatc ttctggactg gaggtagctt gatacatagc cgttaaattg
     4021 attgctggac cgatttttcc tttaagattc aactgatgat acaagtgaat tactctagct
     4081 tgagctaata aaacatggtg attaatttga aagagttctt tttttgaagg cagctctcca
     4141 cttggtggca aaccaatcgc tccaggatga aggatcatcg tgttttgctc attaattgtc
     4201 agccaatagt tcaccttgtc accatactca gtaagcaata cctgtacata gtccacaaaa
     4261 taatcgatag ttgctcgatt taaccaaccg ccctgctcct ctagaaaata aggtaaatcg
     4321 aaatggtaca tggtgacaat cggttcgatt ccctgattca ggcattcatc aattacttga
     4381 tgataaaaag aaattccctt ttgattggtt ttattatttt caatatccat aattcgcgtc
     4441 caagcgatgg aaaagcgaaa agcttttaag cctaattctt taaacagctg tatatcttct
     4501 ttatagtgat ggtaaaaatc cgaggcaact tcaaaattag ctaccccttc tgtatgctga
     4561 tacttgtcaa taatagacgg ttgtttccca tcctcctgat aggcaccctc tgcctggtag
     4621 gcactaatgg aggcacccca taaaaacttc tctggaaatg ctgaaagctg tttgtattgc
     4681 acaaaaatcc tctccttaac taatttgcat caatggttcg tgttccttta agcttccgct
     4741 tgcttcacta attcctgcgt aattttcact gttggtcact accacaatca ctgtatcatc
     4801 gtagccagcg tttctaatgg cagcgaaatc ggcgttgatt aataattgtc ctgctgacac
     4861 ctgatctcct gcttttacaa atacttcaaa gggttcccct tttaaattca cggtgtcgat
     4921 ccccacatgg atcaataatt caataccttc tttagaacgt agaccaatcg catgtttaga
     4981 ttctaaaata gtaatgactt ctccctcaac aggtgaataa atgctgtttt cttctggatg
     5041 aatggctacg ccctttccca atagtccctt agaaaagaca gcatcgttca cttcagaaat
     5101 aggacacacg gttcctttta ccggattttc aacaatgact gcttcggcta ttgccgtttg
     5161 ctctgattca tcagaagtat cgtcaaatcc aattagataa gcaatgataa aggttgcaac
     5221 aaaggcgatt acacacgtaa taattgcgtg aacaatattc attggatttt ctccaataaa
     5281 ggctggtaag gctgctaagc caggggaaac aaaggcatat ctgactaaac cgctcaagcc
     5341 agcatacaaa ccagcaattg caccaccaat catggaagca actaatggtt ttttcagctt
     5401 caaggttact ccatagagtg aaggctcagt aattcccatt aaagcagtga tcccagtgga
     5461 cacagctagc tgcttcaact ctttgttttt agttttcgcg gctacagcaa aggtagcacc
     5521 tgattgagca atattagaag ccagcattcc tggcccattg atcatttcag aacccgtact
     5581 gctcaattgc atagtagcga ttggcgtcat tgcccaagct gtacccgtaa ccaccaaaaa
     5641 tggctgcaaa ccacccatca aaaatggaat taaccaagct gctttgccgt taatccattc
     5701 agcccccatt gctataagat cgttcagcaa cgttccaaac ggtccaatga caaccaacgc
     5761 taaaggcccc ataattaaaa ataccagcat cggcttagta aagaatttaa taaacgaagg
     5821 cgaaattcga tccgcaaagg gctctacata ggacatgatc caaacagtaa agataatcgg
     5881 taaaactgat cccgcataat ctgcagctaa taccggaatt cctagaaaag aaacggcatc
     5941 gccagtagaa aaaagctgtg aaatatttgg atgaagcaaa atgccagcaa cagtaatcgc
     6001 caaaattggg ttgacatcaa actttatggc tgccccatag gctaatagta ctggcataaa
     6061 ataaaaggct gcatcagcaa tagtattcaa aatgatgtaa gtttgactac tgtctgatag
     6121 tacaccagtc aaagtcaaga cggccaaaat ggcttttacc atcccggcac ctgttatagc
     6181 tggaatcatc ggtgtaaagg tggtagaaat gacactaatc aatcttgaaa taatactttc
     6241 ttgattgtct gaagaggggc cctttttaat tgaagttccc acttcctttt gaatttcctt
     6301 gaaggctgtt tggacttcat tgccaatcac cacttggtat tgtccaccgc tatccaccac
     6361 actaattaca ccaagtgttt tttctaaggc tttcgtatcg gctttccttt tatctttgag
     6421 ttcaaaacgc agtctggtgg cacaatgggt taagctgacc acattttctt ttcccccaac
     6481 ctgttgcaat acatttcttc ctacttctct gtaatccatt attctctctc cttaaagcag
     6541 taaaaaagac caagtcaaac cacgccccaa tcaacattga agtgttagtt tgtcttggtc
     6601 ttgcctgcat aatcagtaac atgccaataa cgttattttg ctgtaatcca ataatagcac
     6661 attatgatag cgcaatcaac agggaattta attttttatc ttttcgtttg accgtatagg
     6721 gtaatataac agttagatca catcaactag ggtatatctg cgtatactta ctgctaaaat
     6781 aagtatatct aatattaact ataccagtaa aaccattcct acataaccag cgggaaattc
     6841 ccaaaatcgt gaaagcatca aaaatgcata taacggatca cacaacttca acaattctgc
     6901 tcttgggaaa aattgatgaa tttggtgagt aaaggatgga ataaacagca ttccaacaat
     6961 ataggcaaca atagtgatac ttgttttttt ggtaaaaatc agtaagcaat agccaatttc
     7021 aatcattccg agatataaag gtatcgatag aatgatttgg gctagtattc ttaaaaatta
     7081 actagcaaat gtttaaactg atttatttct aatctacatg tagtaagtat ttcaattcca
     7141 ccaattatca ataaaaatac caaacatatc cataataatt ttttcttttt catttctttt
     7201 atattgttat aacagtgaat aacataaaaa ttcccgacaa tcattgtaat atttttttgt
     7261 cacctgtatt agtatttaat ttataggaaa ctataaaaac tccctagtga atttacacct
     7321 ttgggagttc ctgtttggac ggtatgcata atacatttaa atcaatttaa cattaacacc
     7381 tcagcatatg gtatctccac atatatacgg tctttctttg gatagtactc aatatttatg
     7441 ttgatagcac ttccattgtc taatatagct ttagcccggt atgtgttatc tccattttca
     7501 tgagtaatcg tcacatcatc acatgatcga tttaagttgt actgttcttg taaaatctgt
     7561 gttaccaatg gtttcgatga cttctctaat ccagatgtac ctgtcatttt tgaaaaaatg
     7621 atacctataa tagccaagac aacgataact ataatgataa acttcttgtt catatttact
     7681 ttattcaact ttttatctcc tatctccaaa ataatttgct cttatccctc ttatcagtac
     7741 attgacatcc ctaaaagtac accaaagatt gctccagcta cccctgctat catcaaaatc
     7801 gtacccattt gttcatcttt atctcgatat aagtagccca taataacagc aacagcacca
     7861 aatacaacag gaataaatgc taacgctact accatagaaa tccaaccaat aatcaaatac
     7921 agcttccctg tctcttgtcc atgtacgatt tgttccttca tttcattaat tgtctgctca
     7981 gtacttttct ttactgcgtc tgctccagtt gtctcatctg tttcttgtag tgctccgcaa
     8041 aactggcaat acttactttc atctgttatt tctttgccac attttctaca atacatgtct
     8101 tctcctccta aaaacattca attgtttatt agttaactgt ttactttatt aaatacatca
     8161 gaaaacagct cattcattgg tacacttaat atctcagaaa gcatcttcat ttgatagggt
     8221 ttaggaatcg ttctccctgt ttgccacgaa cttacacatt gctgtgtaac attcattttt
     8281 ttgctaactc cgtttgagaa agtccttttt cttttctgta tcggctgaga ttacttactt
     8341 ttttcatgat tctcccctcc tgttttatta tatacaacaa tatgatgtat ttcaactcat
     8401 aaaatataaa aaaacttcaa ataccattac aaatacaaca acttgttgta ctatactgag
     8461 atgggggtgt attaatgaaa cagaaacaat atgcaaaggt cattagagaa aagcgaaaag
     8521 ctctcgggtg gacacaaaaa gaattagctg aaaaaatctt ctctacacaa caggcagtag
     8581 caagatggga aaattctgta acagagccta acctcgatag cttaaccgct ctttctagag
     8641 ccctaggaac ccctgtaagc cattttctag acaatgttgt cgtagattat gaggaagagt
     8701 ttttggctct ctatcgttct cttagcactg aagatgcagt tcgaacaatt gactatatga
     8761 agctattaaa aaggcaagaa aatgaacgca atcagctatt gaaagattga aaaataaata
     8821 acccaccgaa ctttaacggt gggtgtattg agatgaaata agattaagag ctatggataa
     8881 cctgtctagt ttaatacaat tgggtctttt ctcttcctta ctctccgtcc atcatctctt
     8941 gttacacttg taaattgata aagaggaact aattcaactc ctgataatat caattctttt
     9001 attacttcat ctatccctgc tccttttgct aggtagacta aaaaactact acttgctttc
     9061 acattgtata gtctcttaat atccttagaa gctcgttcaa gagtgaatcc ttgtttaaca
     9121 aagtagcctc tgttttcttt taaagcattt tccacgctgt tattcccaac attacgtaga
     9181 cgttcacaaa cagtgttagt aagttctttc tctgtcatta gatatgttcc ttgccacgat
     9241 aagccctgta aaacttcatg tgcttcatct aaaatcaatt gtttttcctt gctaagttct
     9301 gatcgggaat tttgaggaaa tactctttta gcctcttttt cgttaaaaca tatcttaacc
     9361 cattcataag aaaaatattg atatgtaaaa tgaaattttt ccagaagtgg aaggatatct
     9421 tcattcaatt tttgaatcac agaagttgca ttaaaaacgt ctaatcgata gacattgctt
     9481 ctcttatgat taaagtttcc taacgctttc tcttccttta acctatttag gtattcgagc
     9541 atcttcaaag gaacatcttc atcatctaat ttttttatca atcctataaa agtcataagt
     9601 gatagtaact tattacattt atctatgtca taagttttac catagtaaaa actcattttt
     9661 ttagctaatt gttcccccga caaaatacaa gtcacacttt ccttactatc atcaaaaaaa
     9721 ttaacatcag aaagcaagac atcatagaca cgtcgcattt cctctagata attccttatt
     9781 gtcctgaaaa gtttgtcttt cattgattca agagtgtcaa aaagtacttt tgattcctct
     9841 ttcaattttc gaaaatgtgt aggatacaag tctaggttct ctaatagcca attaaatgtt
     9901 tctacccgac tgtctttctt taaaattagc atcacaactc caataaaatt ttcactgata
     9961 tcacaattac tggaatgaca ataaaaaatg gaatgcccag ttttactggt aaaaatacta
    10021 gcagagggat tatgatcgtt gtgaaacaga catcttaagt ttttacttga cttaagtaat
    10081 ttattcatat caatggttaa caatctttca taaatctcat taaaagacat gtcggaggaa
    10141 tcaaacaggc agtctttaaa ccactgtttc atttcttctt tgtcgtcatt ttttatcaac
    10201 ttaacaaaat cggtttcatt gactagttca tactctctcc ctgaatcact ttgacaattt
    10261 ttagaacatg tcatggtaaa atcaatcgga agctcagtaa tatctaacat gttgtcttca
    10321 ttaattatta tcactgcatc tgacttatat cctccaaaaa acattctatt cgaagcattt
    10381 acattgtcat cacacccggg gatgttcttt ttcaagtatt cgtaaacagc aaccatttta
    10441 ccatagtcag taattgcttc ttttaataga aagacaatct tgtatttttc tagattttca
    10501 gagtaccgaa tacttttttg tatcgcaaac gcagaattat gaactaaatt gatagataaa
    10561 accttttcta tgcttaagta tctactatca tctttactca aatctactac cttccccttc
    10621 tcatctttaa cagtgttatc gacatccaga ataattactc tggtttccac aaaactctcc
    10681 ttgtcattgc ctttattctt tgtcttgctt ggaataaatg attgtgatga atttagtatc
    10741 tctacaaact catctcttgt aacttctcta tagttatcta aacacctatc tcttacatca
    10801 gttttttctt tttttgtaac tggcttctct aataattttt ctttatctac ataaattgga
    10861 atattaatca ttgatgtttc catttgtgtt tcctccttat aaaattctgt taaagactaa
    10921 aacatacaga taataaaaac aaactcttta ttactatatg ttttagtctt atttgtttac
    10981 tcaaccttta taccgttcca tgaaactatc aatatcagat tttttaaatc taatgaccgt
    11041 atcaattttt ataacaggta acccgtattg agaaacatat tttctaatcg ttcctactga
    11101 tacacctaga tattcacttg cctgctgata gtccatatac tctagagtga ctccagaaat
    11161 aatgtcttct agcataggct ttagcactgt aattatctct ttcacttgtt gttcaacttg
    11221 tatagaaaca atgctatcaa tgatttgtag agacatattt ccccctcctt tcgtgattgc
    11281 ttgaacaaat tttctaagaa ttatcttcgt attttttgct caaaataaaa gtattttgtt
    11341 attaaccgat taatcaaaca aaaaatgatt accagttcat cgacatacac ataatacctc
    11401 gataaaaaag aggtgtcaat atctttgtaa aatttattta caacacccct ttttcgaggt
    11461 atactaattt taggaggtgt ggtcaatatg ataaaacgtc caccaataaa ttatttagaa
    11521 cgaaaaaaga tactcggaac aaaaataaaa gctataagaa agagtaaaaa attaacacaa
    11581 ccagcatttg gtcttatgat taacaacggt caattaattg acaaaaaaac tatctacgaa
    11641 tgggagaagg gaacctattt accaatacca gagcgattat cccgaattgc tgatttggga
    11701 aatatgagta tagaggagtt agtttgtggc aatgtagaag aatatatttt gggaattatt
    11761 ctttatagag atagcattgt actagatggt ataacatttc cagataaaaa cctgttccag
    11821 catcttcgtc aacagttccc accagtacac tctaatttag atacatggct ggatagatat
    11881 tccaaattag aaccagagat gcaagaattt attgctaaca agacttgtaa taaagttaaa
    11941 aatgaaaaaa ttagtctttt caatatctta aaaatagaag aattattcat caatgctatt
    12001 gtagaagaat ttgacaataa cattcttttc ctcactagca gtatagaaga actactagaa
    12061 agaatggtag atgaatggct acctattcaa ttgaaagaca tgtcttatcc cgaagaagct
    12121 gtgagagaaa ttactgataa tataaacaag ctagaacaaa cgatttcatc aattgggaaa
    12181 aaatacacta agaaaaaaat gaagggaggt gataccatct agtggtaagt actccttgta
    12241 aactaagagg agatgatttc atggcaaaaa tatcaaagta caaaaagaaa aacggtcaag
    12301 tggcgtggat gtataaagga cacattgcca ccgatccacg aactggtgaa aaaataaata
    12361 ctacgagaag aggttttagt agcaaacaag aagctcaaaa agattatgac gagtacagac
    12421 atcaaatatt atacggtgtt aaaaagaaag cacctgatat gacatttgaa gacctgtata
    12481 atgaatggat aactcatcag cgtaccagtg ttaaagcttc aacaatcgca atctcagtaa
    12541 gatacgcaaa taatcaaata cttccagcat ttggtaagct taaactatcg aatatctctg
    12601 tcccatattg tcaaaaagtg gtagatgaat ggcacagtaa atatgaaagt tacgattata
    12661 tgagaaaaca gactgcacaa attttacgct acggggttgc aatgcaatat attgacaata
    12721 atcctatgga aaaaacactt cttccacgaa aaaaagagta tgagaaaaat cgtaaatttt
    12781 actcaaaaga ggagcttaat aatttactgg atgcttttaa agattttggt aacatgaaac
    12841 aatacgcctt cttcagatta ttggcataca caggtatgag aaagagtgaa gtactcgctt
    12901 tacagtggaa agacatagac acgtttaata aagaactaca tgtcaataaa actcttgctg
    12961 tagatgaatt tggtaaagtt ataattcaat ctccgaaaac aagagcttct agacgagtta
    13021 tctctttaga tactgagact ctttctatcc tcaacaactg gaaattacag caaaaagaag
    13081 agtatttaaa acttggatac aatactagct ctaaagagca acatgttttt acaacagtta
    13141 aaaacactct atacattcca aacactgtta atgattggtt aagatatatt ttgaaaaaat
    13201 ataacttgcc tcgtattaca cctcatgggt ttagacatac acatgctagt ttattattag
    13261 aagcaggaga atctgtcaag gtagttcaac aacgattagg gcatgaaaat agtaaagtga
    13321 cattagacat ctatgcacat attacaaata atgcacctaa gaaaacaggt caagactttg
    13381 ctgatatgat ggctcatcag taaaagagct ggtcaaaatc tggtcatttc tagtatacag
    13441 gcaaaacaaa aaagctagaa cccttatata tcaagggttc tagctcctat aacaggttta
    13501 cccaacactg ccttccatct cataactgat caatcgattg agttcgactg catattccat
    13561 tggaagttct ttggtgaatg gttcaacaaa gcccatgacg atcatttcag ttgcttcaga
    13621 ttcggtcagg cctcggctca tcagatagta gagttgttct tctgagattt ttgagacttt
    13681 ggcttcgtgt tctaaagaga cttggctgtt gtggatctca ttgaatggga tcgtatcgga
    13741 tttcgaccat tcgtccatga tgatcgtgtc acattcgata tgagagatcg aacccgcact
    13801 gtttttggca aaggttactt gtcctcgata gtttacttct ccgccgtctt ttgaaattga
    13861 tttagagacg atagagctag atgtatttgg tgcattgtgg atcatttttg cacccgtatc
    13921 ttggatttgg tttgctcctg caaaggcgat ggagagcatg gtgcctcgtg caccttttcc
    13981 atctaagtaa acacttgggt atttcatcgt tgtttttgca cctaggtttc cgtcgatcca
    14041 ttcaacggtt gcgccttcgt atgcttttgc tcgtttggtt actaagttgt acacattgtc
    14101 tgaccagttt tggatcgttg tgtaacggca atacgcatct tttcttgtaa agatttctac
    14161 gatggcggca tgcaggctgt tacttgaata agtaggtgcc gtacaacctt cgacatagtg
    14221 gatgcttgct ccttcgtcaa caatgatcag cgtacgttcg aattgccccg tgttttccgc
    14281 attgatccgg aagtacgttt gtaatggaac atcgactttg acgccttttg gcacgtaaat
    14341 aaaggtccca cctgaccata cggctgaatt cagcgctgct aatttgttgt cggttggcgg
    14401 tacaagtttt gaaaagtact ctttgaataa ttcagggtat tctttcaaag cagagtcagt
    14461 gtcagtaaag acgattccta acttttcgaa ttcatctttc atattatggt acacgacttc
    14521 tgattcatat tgtgcggaag caccggctag ataagctcgt tcagcttctg gtataccaat
    14581 cttttcaaat gtatctttga ttttttctgg tacgtcttcc cagtcacgag cgggtttgtc
    14641 acttggtttt tggtaatatt tgatggcatc gaaatcgatg tctgaaaggt cggggcccca
    14701 tgtttgcatt ggcattttgt taaatgtttc tagagatttc agacggaatt caagcatcca
    14761 ttctggttcg cctttgattc ttgacatctc acggatcact tcttctgtca agccttctcc
    14821 tgtactgaaa accggttcga catcatcgtg aaacccgaat ttatattctt ctaattctgg
    14881 tacgcccatg ttctcactcc tcttccttgt ggtaatgatg gaaagctgcg gtaccatcgt
    14941 tttccattgc ttttcctagt gctttccagg caagtgtcgc acatttgatc cgagcgggaa
    15001 atttagctac accaccaagc atagcagcat cgcctaattg gtcgggatct ttgacttctt
    15061 ttccttggac aagctgtaga aagtctacag ttaaatgttc tgcttcttct attgattttc
    15121 cgatgacggc gtctgtcatc atcgaggcac ttgccgtact gatggagcag ccactgccgt
    15181 caaaggcgat atttttgatg attccgtctt ttacatcgac ttgcaattcg atcacatctc
    15241 cacatgtggg gttgttcaat tcgatcttgc ttgtcgagtc agtcaagctt ccacgatgat
    15301 gcggatggga agaatgatcc aagatcactt gacggtataa attgtctaat ttagatagtc
    15361 ccatgttgga aaaactcctt tgttgccatg attgcttcaa ctaaacggtc ggcgtcttgc
    15421 gttgtgttgt agaaataaaa gctcgcgcga gcagtcgctg atacttcaag gtacttcaat
    15481 agcggttgcg cacaatgatg acctgctctg acggctaccc cttccatgtc taaagctgtc
    15541 gcgacatcat ggggatgtaa cccatccaaa ttgaatgcaa cgactcctgt ccgaaaattc
    15601 gggtcttgtg gaccataaac agtcaatcca tcaattgctt gtaattttgg caacacataa
    15661 gcggctagtt cttcttcata tcgatggata ttgtccatac cgagtttttg caaataatcg
    15721 attgcatggc ctaatgcgat agcgccggcg atatttggtg tccctgcttc gaatttccaa
    15781 ggtagttctt tccatgtact gtcgtataat tcgacaaaat cgatcatttc gccaccaaat
    15841 tcaacaggtt ccatttcttc taaccatttt cgtttaccat ataaaacacc aatacctgtt
    15901 ggtccgcaca ttttgtgtcc gctgaaagca aagaaatcac agtctagtgc ttggacatca
    15961 atggccatgt gcggggcaga ttgagcacca tctactacga tgaccccgcc gttttcatgg
    16021 acaagttcag ctaattcttg aacaggattg aagacaccta agacattgga tacatgagca
    16081 atggagacga ttttggtttt gtccgtaatc tttttcgctg catcctccat atccaggaag
    16141 ccttcttctg ttagttcgat atatttcaag acagcacctg ttcgttttgc caactgctgc
    16201 cacgggataa cattagaatg atgttccatg taagagagca ctatctcgtc tcctgctttg
    16261 atatagcggt cgccgaaggt tctggctacc caattcaagc ttgtcgtcgt accacgagta
    16321 aacagcactt ctgctgtttc ttttgcatgg atgaacgccc gtactttttc tcttgcttgt
    16381 tcataatcat gggtcgcgcg ttctgctaac gtatggacac cgcgatgaac attggcgtta
    16441 tcgtgttcgt aatagtacgc taatgcctgg agtacttgtt ttggcttttg ggtcgtcgct
    16501 gcattatcca gataaactaa aggttcatca ttgacgtctt gaaataagat aggaaaatca
    16561 ttgcgtagct ttttagcatc gatcatccat tcaacttccc ttcgattact tcgactaatt
    16621 ctttccgaac ttgttctaca gggattgctg ttaagacaga accgaggaat cctcgaatca
    16681 ctaagcgctc tgcttcttct ttatgcaatc ctctactcat cagatagtac atttcttctg
    16741 gatcaactcg tcctacactg gcagcatgtc cagcagttac ttcgttttca tcgatcaaaa
    16801 gaataggatt cgcatcacca cgtgctttat cagaaagcat caagacacga ctttcttgtt
    16861 gggcatctgc accttttgcc cctttcaaga tgtggccgat accattaaag gtcaatgttc
    16921 ctttttctcg gatcactccg tgttgcaaaa tatgcccgat cgtatgaggg gctttattgg
    16981 ttactcgtgt atcgattcct tggatttgtc tgcccgagct gattgccacg attttgactt
    17041 ctgcgtgtgc accttctcct gctaaatctg agtcaaagtc agcgatcaca tgaccgtcat
    17101 tcatgacacc aattgcccag tcgacagaag catctcgtaa aatgtgccca cggcgattca
    17161 tataagaagt aatattttct cctaattgat ctacggctga atatttgatt tttgaaccag
    17221 ctttagcgat gacttccacg atgatattac ctgatgattt tgctacttgt tctttggttg
    17281 tctggaaacg ttccagataa gaaaattcac tatgttcatc tgccacgatc aacacatgct
    17341 tgaagaagtg ctcatcggat gcgccatctt gaatgaataa ggactcgagt ggttcatcga
    17401 tcacgacatt tttaggcaca tacaggaaaa taccgctgtt cataaaagct acatggagtg
    17461 cagtcaattg gtcttcgttc atgtttactg cttttttcat ataatattct tggactagtt
    17521 ctggatattc gatcattgca gtgaacaagt cggtaaaaat gactcctttt tctgctaatt
    17581 ccacaggcag ttgttcaaaa atcgtccatg aaccttgttg gacaagcaca ggattgtctt
    17641 tcattgcatc aaatgccgga atcgtgcctg tttcactgat ggtttgtgtt tctttcacat
    17701 caaataacga ccagcgatgg aatttcaccc gatcgatatg cggcaatggc agttcatctg
    17761 ctttcgctag tgcgtcttga cggaaggttc tcatccaatc aggttcgcct ttacttaaag
    17821 aaaaatcatt taccgcgtca agataatcga gccagttttt ttctttcatt cttgctcccc
    17881 cttacgcttc ttcttcttta tagtcgattc ctaattcttt actgatacca gcgtagcctt
    17941 ctgcttccag acgtttagct aggtcagcat tccctgtcat gactactcgg ccttccatca
    18001 tgatgtgaac gacatcaggt gtgatatagt tcaataatcg ttgatagtgg gtgatgatca
    18061 atgcaccgaa attgtctccg cgcatttcat ttactccttt agcaacgact ttcaaagcat
    18121 cgatatccag acctgaatcg atttcgtcta aaattgcaaa tgtaggttct aacatcaaca
    18181 attgcaggat ctcattccgt ttcttttctc cgccagaaaa accttcgttc agataacgtt
    18241 cagccatttc ttctggcata tttagtaaag ccattttttc atctaacttt ttcaaaaatg
    18301 ccataacaga aattttgtcg ttttcatcac gtttcgcatt gatcgctgca cgcatgaatt
    18361 ccgcattcgt gatacctggt atctcacttg gatattgcat agctaaaaat aagccaagtc
    18421 gcgcacgttc atctacttcc aagtctaaaa catttttccc gtcaaacaaa atttcgcctt
    18481 ctgttacttc atagtttgga ttgcccatga tagcggcaga taaggtagat tttcctgtgc
    18541 cgttaggtcc catgatggca tggatttctc cggttttcat tgttaggttt acgcctttaa
    18601 ggatttcttt ttcctcgatc gacacatgta gattttttat ttctaagaca gacatgcatt
    18661 atacccccaa attctctttc gttctcactc attttagact aattgagaat gaagcgcaat
    18721 gaccttcctt actaaaatca aatatctttt atttattatt aaacaatttt gatttctaaa
    18781 ttagaatagg tataaaaaag atgagaaata agccattaca gacttatttc tcatcttttt
    18841 tgttccatac cttattttgc atcagccttt actggtttaa cagagccgcc ccatttgtct
    18901 gtgatccatt cttggacttc tttgcggtga agcacttcaa tcagtttttt gattttgtca
    18961 ctgtcttcat cacctttacg agtcgcaata atattcacgt aaggagagtt gtccttttca
    19021 agcaatacgg catcttctaa tggattcaac cctgcgccgt aagcgaagtt tgcgttgatt
    19081 gcaactaggt caccttcatc attttggtac gtagaagcta aaagtgatgg gtcgatcgta
    19141 tggttgaact tcaagttctt agggttttct tcaatatcat cgaatgttgc tgtttccaga
    19201 tctactccat ctttgacttt gactaagcca gcatcttgta gaattgtgat gatgcgtccc
    19261 cagtctgatt cagaatttga agtaatgatt gttgcaccat cttttaattc ggaaacatct
    19321 ttgacttttt tagagtacaa gcccattggt tcgatgtgga cagcaccggc attgacaaag
    19381 tcatatcctt tttctttgat ttctttgttc aaataaggaa tatgctggaa gtaattggca
    19441 tcaatgtcgc cttcttccaa agattggttc ggtaatacat agtcatcgaa tttgacgatt
    19501 tcaagatcga ttccttcatc tttcaataat ggtttcacat gttccaaaat ctctgcgtgc
    19561 ggtgtcggtg aagcgccgac tttcaatgtc gtgtcgtctg ctttatttgc tgaatctttg
    19621 ctgtcgctgt tgttaccgca tgctgctaat cctacagtca gcaaaagcgc tgctgcaaat
    19681 ccaaaaattt tctttttcat atcctacatc cccctatatc ctattatctt ttgtctgttt
    19741 tcttagttaa gaaatcaccg attccttgaa cgataaatac gattagtaaa ataattaaag
    19801 tcgcaacgaa tgtcactgtt agattaccac gctggtagcc ttcctgccaa gcaagacctc
    19861 caagtccacc tgcgccgatc gcgccggcca tcgcagtaaa tccgatcatc gagatcgttg
    19921 taactgttaa tccagaaatc aatgcgggaa tactttcagg tatcaagacc ttccagatga
    19981 tttcccagta acttgctccc attgcatctg ctgcttccag tacaccaggg ctgacttcac
    20041 gaaaagcaat ctctactaga cgggcataaa atggtgctgc ggataaaaca agagctggaa
    20101 tggctgcttg cgcacctagc atagtgccta cgattgcttt agtaaatgga atgatcaaaa
    20161 ccatcaggat cataaatggc gttgaccgga aaatattact gatgatcgat acgattccat
    20221 aaatgattcg agcatacggt ttgtttttgc gtccaataga gtaaaggatc aatcccaaaa
    20281 ctaatccgat gatcgtcact aagaccattg agattaatgt catatatagt gtatcaagga
    20341 tagcctgatt catcgtttcc gggttgattt gtttaaaatc tagatatgtt tctgaaaagc
    20401 ttttatccac gatggatcac ctcaattcct actccttgtt ctttgatgaa cacttctgct
    20461 tgatctaatt ctttggtttc accagtcatc aagacagtca atgaaccaaa ggaaccttct
    20521 ttcacttgtt tgatctttcc atacacaacg ttgacatcga tgttatagcg tcgaatcgct
    20581 tgggaaatga ctggctcgtt ggcatttctt tcgctaaagg tcaaagttgc caaacggccg
    20641 cttggatttt ctttgatgag ttcagctaat agttctgtcg aatcagcttc tggttcgatg
    20701 tcttgttgta caaagcgttt ggttacttct tttttcggtt gtctgaagac agtcaatacg
    20761 tctccttctt ctacgacttt ccccaactcc atcacagcga ctttgttgca gattttgcgg
    20821 atcacattca tttcatgtgt gatcaagacg atggtcaaat tcaatttctt attgatcgct
    20881 aacaataagt ctaatacttc ttctgttgtt tgcgggtcca atgcgctagt agcctcatca
    20941 caaagcagga tctcaggatc atttgccaat gctcgtgcga taccgacgcg ttgtttctgt
    21001 ccgccggaaa gttgtgaagg atatgcttgt ccgcgtcctt ctaacccgac taaacgcaac
    21061 agttcttctg cccgttcttt acgtttgctc tttggtacgc cagctaattc cagcggcagc
    21121 tggatatttt caagtacagt tcttgaccat aacaggttga aatgctggaa gatcataccg
    21181 attttctttc ggaatgtacg taattctttg ttttttaatt ttgtaatatc ttgatcgttt
    21241 acgatcactt cgccgctcgt gggaagctca agtccattca ggagacggac taatgtactt
    21301 tttcctgcgc cagaatagcc gacgattcca taaatatccc ctttttcaac gtttagtgaa
    21361 acgtcattga cggcttggat gtttccgttt ttcccattga atgtcttttt gacattcgtt
    21421 agttggatta atgacatgcc attcacatct ttctcttata atttttcaaa caaaaaagcc
    21481 ttcgccctct tgccttaagc aaaaggacga aagcttgaac ttccgtgtta ccaccttgat
    21541 ttaccgttac ttcgcaataa cagcctcttc cagtacttgg acttagcttc tttccgtata
    21601 ctgtcgcgct gtaacgggca ctcccgtagt aagtttgctt acgctcgctt actctgctct
    21661 aagaccatct tccatctcat tttcgttacc cattttcagc aaacagggct ctcttcaaac
    21721 gtccgtgaca tgtactcttc ttttcaaagc tttctcgttt catataggat tgcttatgat
    21781 tatagcaact ggaagaatca gtgtcaactt ttttcaagtg attttctgat tttataattc
    21841 gtcaaattct tttggatcaa catctttgaa acttaagatc cacgcattca tttcatctga
    21901 atcattcaag atattgatat cttcaccgat tttatcatta acagaagaaa ctgtacccgt
    21961 tagcgggctg gcaaattcat tgaccgcttt ttccgcttca acttcgatca gaggttcatc
    22021 tttttttagc gattgtcctg cttttggcag attggcaaac gtgatgtctc caagttcttc
    22081 ttgcgcttca tttgtcaaac caacacagta ttcttttcca ttaaataaga tccaaaggtt
    22141 gtcctttttc ttcaaatgct tgcctgccat tttatatcag ttctccttca taaatttttt
    22201 cattgaatcc aattgcaaca agctggtcct ctcgtaagat cagtggtcgc ttgatcagca
    22261 taccatctgt cgataagact tggctcgctt ttgaagccgt aaactcgcct acttgatctt
    22321 tcagtccaag ttcccgatat ttcatcccgc ttgtgttgaa caggcgacgg attggtactt
    22381 gactcgtttc tagccaagtc tcaatcgttg aggccttcgg tacttctttg atcatatcaa
    22441 cggtttgata actaacgcca tgctggtcta accacgcttt ggcttttttg catgttgaac
    22501 atttcgggta ccagtaaaag gtgtacaatt ttcttacctc cttgaagatc ttgcaggtgc
    22561 ttcattttgg tatctcatcg ataatatcaa cccgataccg atcatgttcc ctaaaatcga
    22621 ggatcctccc tgactaatga aaggcaatgg gatccctgtt aaaggaagta atccgatatt
    22681 tgctccaata ttctcaaaga catggaacag cagcatcatg atcaaaccgc ttgcgatata
    22741 ggcgtaaaat tcattattcg tatcgaaaca cacccgaatc atacgataga ttaaaataaa
    22801 atacaagaaa atgacgaatg caccaccgat aaagccgaag ttttcaccga taacggtaaa
    22861 aatcatatcg gactcacgaa caggcacata gatattgctt acgttgaatc ctttaccaaa
    22921 caagccaccg gtaccaattg ccaaaagtcc ttgggccggc tgataactca ttcctgacgt
    22981 atcatggaaa gggtccagcc atgaatcaat acgtgcaaac tgataagatt tgaatccaac
    23041 tttataaagc aagtctcttc cgccttcagt cgtaaccaag aagatcgttc ctgctccaac
    23101 gactactgcc aagattacta caggtgcgat gatgcgccaa gagattccag acatcaggaa
    23161 aatcccgcca aagatcgcaa gaaagacaag catcgttcca aagtcatctt gggccatgat
    23221 caatgctaaa accggtattg tcacgatcaa gagcttccca atcagccaaa agtccgattt
    23281 catcgtccgt tcttttactt gcgtattatg tttagttacg atcagtgcca tcatcaagat
    23341 gtacgcaatc ttcatcaact ctgctggctg gaaagtaaac gcaccgaatc gaaaccagtt
    23401 tttagaccct gttgaagcag ctaaattctg atcatagaat ttgagcaaga gtcccattac
    23461 cactaacccc aaaccataaa ggtaaggagt cagtttccag atccatttgg aattcaaatg
    23521 catgatgaca acgattgctg ccgctccaac taaataccag acaacttgca tccctacgcc
    23581 tttcaagact gctggattgt tcggatcatg gctaagtgct acatataatg agagcagacc
    23641 aatcaaacat aacagaaaga ctggtaaaat cacgccataa tcaatacgat tatcgttcga
    23701 agcttttaat tttttttcca tgtttcatcc cttttcttaa aaaccatact gctgattatt
    23761 atagcggtcc agttagataa tggaaagtct ttccatagac atttgggaaa aattaacttt
    23821 ccgtttgtgc agttgcttga gcaaatgcag tacaaaagcc tactgcttat ctttagtgta
    23881 tcatagaact ttttttgata catgcaatta tctaccagct gagattctcc tcgctgtgag
    23941 aagtttctgt gctttcattg tatcgaagga tctcttcggc aatctctagc agctgatcag
    24001 aaaccagatt ggttcgttgg atgaaataaa aatatcgatg gaaattcaac ggagtcattg
    24061 gcacattttc tggaacagag cgcttagaca aaatcgagcg accgattcct tccttcagca
    24121 acgcaacaat tacatcgtta cttttcacga tcatcttctt atcttggata ttcatctctt
    24181 caaaataacg ctgcgtgtaa tgaaaaacac cagagtttgc ttctcttaca agccacaatt
    24241 tgctttttgg gtccccagcg atgactagct ggtcttccat caaagagtat ctttgtacgc
    24301 cggaagtctc taatggcttt tcgataaaac caaaatcgga ttcatgtttc gctacttgtt
    24361 ctaatgattc atgagaattc gtgatttcga tctcaaaatg cactttagga aaccttttga
    24421 tcagatgttt catcaactga ggcaaaagat agacagcaaa ggtgtgggaa gcaacgatcc
    24481 gacatacttc ttcttcattt tgttcattga gcaatttttg ctgagtttct tcccattctt
    24541 ctaacaaaac cagtgtccgt tcatataata agtcggcttg cttagttgga agcatctctt
    24601 ttcttccgtt acgttgaaaa agatcgatat tcaattcccg ctccaactgt ttgatttgat
    24661 tcgagactgc tggttgagat aaaaacagta cttctgctgc tctggaaaaa tttcttgttt
    24721 catatactgc tcgaaaagtc gttaataact taaacatggc accacttcca taacttttta
    24781 tgataattac tataaaaact atttgattta aatatacaaa aaaccatcta taatagaaat
    24841 gtacaacaaa acagttgctg atccaactag taacttagat gaagacaatc agctgtctgc
    24901 ttgctcgtaa tcatacattc ctattcattt tacaatgtat tcgttcatct tggtactaaa
    24961 atctattaaa taaaaaggag aatattatat atgaagaact ttttgaaaat tattccgatc
    25021 ccgatctgcg ggttgatcct tgggttagct tcccttggaa atctgtttaa agactatcac
    25081 catgttgctt taggcaatct aactggcggt atctctatga ttcttatgat attcattttt
    25141 gttaaattgt ttatcttatt cgaacacacg aaacaaacgt tgcatgatcc aatcatcgcc
    25201 tccgtttcac caacttttac gatgtcactc atggttattt gtacttattt tgtttcatat
    25261 gaaagtattg caccaattgt caaattcatt tggctgtgcg ctgttatctt ccaagtgatc
    25321 cttgtctttt atttcaatta tcaccatgtt atcaaagctg atctttcaat tgaagcaatt
    25381 tatccaagct ggtttatcat ttacgttgga tttggggtca tcactgtaac tgccgggaac
    25441 ttcttcccac ttattggaaa aattttcttt tggatttcat tgatctgcta tgcgttctta
    25501 ttgccgatca tcatcaaacg tgtctttttc gtaagaaata tggctcatcc gacacgtccg
    25561 ctgattacga tcgttgcagc acctggttct ctttgcctaa caggttatct taaaaacttt
    25621 gctgaaccta atttttatct tgtcgtagca ttgttcgctt tatctcaagt attgtatttc
    25681 gttgtgctgt ctatgcttcc acgtttgttc aagcttcgtt tttatccaag ctatgcagcc
    25741 tttacattcc cgcttgttat ctctgcaaca gctatattta ctactgttca ttacttcaac
    25801 agtttaggta tctatagtag cgtattggat ttcttaaaag ttgcggaatg tctgtttgca
    25861 agtgtagttg tcttctacgt tcttgctcat tacgtacgtt tcttaattaa agaacatagc
    25921 aaacatggaa aatttgtttc taaaaaaatc gcttaataat cgattcaata ggttgtgaaa
    25981 aagctgttct gcatcaagta ataagaacgg ccaaacaaaa acagctgttc atgtttttgt
    26041 actggttggg cttattaccg cagatgcaag cttttgaaca ccgtttacca agaggtcgta
    26101 a
//
LOCUS       DADGHT010000032        25875 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.032, whole genome shotgun sequence.
ACCESSION   DADGHT010000032 DADGHT010000000
VERSION     DADGHT010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.032"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..701)
                     /locus_tag="JX887_001200"
     CDS             complement(<1..701)
                     /locus_tag="JX887_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAX1257203.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDV"
     gene            849..2402
                     /locus_tag="JX887_001201"
     CDS             849..2402
                     /locus_tag="JX887_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1257204.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            complement(2510..3592)
                     /gene="uxuA"
                     /locus_tag="JX887_001202"
     CDS             complement(2510..3592)
                     /gene="uxuA"
                     /locus_tag="JX887_001202"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAX1257205.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(3583..5229)
                     /locus_tag="JX887_001203"
     CDS             complement(3583..5229)
                     /locus_tag="JX887_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAX1257206.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            5413..6075
                     /locus_tag="JX887_001204"
     CDS             5413..6075
                     /locus_tag="JX887_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1257207.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            6219..6782
                     /gene="ahpC"
                     /locus_tag="JX887_001205"
     CDS             6219..6782
                     /gene="ahpC"
                     /locus_tag="JX887_001205"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAX1257208.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            6792..8321
                     /gene="ahpF"
                     /locus_tag="JX887_001206"
     CDS             6792..8321
                     /gene="ahpF"
                     /locus_tag="JX887_001206"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAX1257209.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            8478..8828
                     /locus_tag="JX887_001207"
     CDS             8478..8828
                     /locus_tag="JX887_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAX1257210.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            8927..9457
                     /locus_tag="JX887_001208"
     CDS             8927..9457
                     /locus_tag="JX887_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257211.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            9611..10762
                     /locus_tag="JX887_001209"
     CDS             9611..10762
                     /locus_tag="JX887_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAX1257212.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(10871..12910)
                     /locus_tag="JX887_001210"
     CDS             complement(10871..12910)
                     /locus_tag="JX887_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAX1257213.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKIAFDSLGGKAASTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFKTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(12968..13525)
                     /locus_tag="JX887_001211"
                     /pseudo
     CDS             complement(12968..13525)
                     /locus_tag="JX887_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            complement(14064..14270)
                     /locus_tag="JX887_001212"
     CDS             complement(14064..14270)
                     /locus_tag="JX887_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257214.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(14286..14900)
                     /locus_tag="JX887_001213"
     CDS             complement(14286..14900)
                     /locus_tag="JX887_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAX1257215.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(15047..15730)
                     /locus_tag="JX887_001214"
     CDS             complement(15047..15730)
                     /locus_tag="JX887_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAX1257216.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(15839..16297)
                     /locus_tag="JX887_001215"
     CDS             complement(15839..16297)
                     /locus_tag="JX887_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAX1257217.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(16381..18144)
                     /locus_tag="JX887_001216"
     CDS             complement(16381..18144)
                     /locus_tag="JX887_001216"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAX1257218.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(18365..19825)
                     /locus_tag="JX887_001217"
     CDS             complement(18365..19825)
                     /locus_tag="JX887_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257219.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(20033..20959)
                     /gene="glsA"
                     /locus_tag="JX887_001218"
     CDS             complement(20033..20959)
                     /gene="glsA"
                     /locus_tag="JX887_001218"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAX1257220.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(20982..22409)
                     /locus_tag="JX887_001219"
     CDS             complement(20982..22409)
                     /locus_tag="JX887_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1257221.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(22440..23654)
                     /locus_tag="JX887_001220"
     CDS             complement(22440..23654)
                     /locus_tag="JX887_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAX1257222.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(23995..24237)
                     /locus_tag="JX887_001221"
     CDS             complement(23995..24237)
                     /locus_tag="JX887_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAX1257223.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(24269..24826)
                     /locus_tag="JX887_001222"
     CDS             complement(24269..24826)
                     /locus_tag="JX887_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAX1257224.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(24839..25027)
                     /locus_tag="JX887_001223"
     CDS             complement(24839..25027)
                     /locus_tag="JX887_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAX1257225.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(25040..25606)
                     /gene="amaP"
                     /locus_tag="JX887_001224"
     CDS             complement(25040..25606)
                     /gene="amaP"
                     /locus_tag="JX887_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAX1257226.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         7585 a         5043 c         4518 g         8729 t
ORIGIN      
        1 acatctggtt tttcttctgg gtctacatct ggtttttctc caggggttat ttcaggtttt
       61 gattcattgt ctggctctgg ttgagtttct gtatcgggtt cttctccagg ttctatttcc
      121 ggtttctgtt ctccgtctgg attttctgta ggcggtactt ctggcttatt ttcattttct
      181 ggtttatctg ttggttcttc aacaagatct cctcctgagt cgatagctga atcttgctca
      241 attgtctgcc gctgactata cggcgttaaa tgatgatgat cgttcggtag tccatctgat
      301 accttgacag taaaaagcgc tggttttaac aagtcctgat ttaatgtaac ggtgaaggta
      361 aatatcgctt gcttgtgttg gatagtcaaa gtgttctcgt catagccaat cgacaaagcg
      421 ggatcaacat tctcaaatgt aacagctgat tgtagtatag gtgctaagtc tcctgaatag
      481 tcaatttttg ctttgatggt cgctgtttgt ccttttctta attttgcgac tcctgaattg
      541 aaggatgaaa attcatcctg aaaggtaatt cgattgacgt tggcccactt ggtttctgtc
      601 catttggctg tttctatctc ctctgtgtgg actgtctgat ttatagtaag cgataagctt
      661 aaggctgcaa atgttgatat taagatggtt gaatatctca taactctctc actccttgat
      721 ttttttgtat gcaagaaata agatagtaga gattctacct atatgtttac tgtttttttg
      781 tctaaattta tgaaaaaaac agtaatattt tcaagtttta acaatttaag taaaaaggag
      841 cctctttcat gcaaactcaa gaagcgatta aaacgtttct cttgaagaaa aaaagcaata
      901 caaaattaga tatttttctt ttcctatctg aacatcgttt ctttattact acacaatatt
      961 tagcagatca tttccatatg tctgaatcaa attttttact atacatcaaa gaattagaac
     1021 aagactttga gcgtctcaat ctaacagaac tgcatattga taagcaaaaa ccttttttaa
     1081 agttgaattt tgaaggaatt gatccggctt actgctatta tcgtctattt ggaagatact
     1141 gcaacgaatc agtcagttat cagatcttga cttctttgtt cagctgtcag acaaattcga
     1201 ttatcagttt aagtcagcaa acaaactata gtgcctctta tttgtatacg aaaatgaaaa
     1261 agattaatgc atttttagca ttgtacggtt tgtctatctc cttttctaat aatggcagaa
     1321 agtctttttc tggaaaagag gtacaaattc aatatgcagc attagatatt tattggaaca
     1381 tcttttcaag tactgctaca gaattttatg atgaagatcc gcaagtagtg gcttttatga
     1441 tgaatacttt ttttaaaaaa gaagtacttg accgactaaa tagcggtatg atagataaat
     1501 tatattttct attaaaaata tgtaaagaga attttcctgc aacttctgtg aaagacgtac
     1561 aaaaagaatt cacagagtat gaatatattg acttttttat tgatccctct gtagatattt
     1621 tgcgacctaa tctgccaatt tgtcgcgaac aacgcatctt agtgaatatt ttagctcgac
     1681 tttctatcac gaaaatcgaa tcggaagaaa caagcttgga gcaatacaaa cttttaaaaa
     1741 aagcaaacgt tcctcatgtt ctttattcaa gagaaatggt ggagtccttt tgtactgtat
     1801 ttgatttgtt tatacctgaa aaagaaaaga ttctttactc attggcattc gcacgaaata
     1861 aactttataa tggatttctt aacttcaatc aaccaaatac gccccttcct actttcatgc
     1921 tttatcaaga acatagcgtg ttgaaagaag tccaaaccgc cattgaacaa ttttatatgg
     1981 atttcagaga acaaaatcaa cacttgttac cagttatttt agaaaaggaa aatgtgcaat
     2041 ggatggttga agacctagta catttgtatg atcgctacaa aaaacagccg cgaattgtga
     2101 ttggtgtgaa ctatacgcgt gatttttata tcagtaaaga tctgatcgtt aagatagaac
     2161 aaattttttc aaatgaatcg atcaaaatac aaaatgattt tatggagaac tgcaacatcg
     2221 ttatcagcga ctgccctttg aaacaattgc cttctcatat caaaaaaatc tatattttaa
     2281 aaggaatcat cacaccagaa gactggaaaa aagtgattat gaggatctca gaatatatct
     2341 ttgaattaaa agaagaagca ctcatggatc aatcgaaaaa agaaaatcaa gttacttcct
     2401 agaccaaata agatacataa atccgaatgc ttattaacaa cctccggatt tatgtatcaa
     2461 gaatttgaac atccttctta tttacataat aaaattacag tttttttcac taattatctt
     2521 tacttttgtt tcctttttcg attgcttccc ataatccatt tagataaaca gcacctaatg
     2581 ctcgatcata taagccgtat cctggtcttc ctgtctcatt ccagatcatt cttccatgat
     2641 caggacggat gtattcgtta aatccgttgt catacattgt ttttagtatg cggtacatgt
     2701 ctaatgaacc gtattcggat ttatgcggtg cctcatagaa atctcgatta gctaaaaatt
     2761 taatatttcg aacatgtgca aatgggattc gatctctttg acaaaattct gctaaaatcc
     2821 catatacatc attttctgga tcttctgcaa tactccctgt acaaagagtg attccgttat
     2881 aagggctgtc tactatgcgg cacaaccaat ctaaatcttc tcgattcttt acgattcgag
     2941 gtaatccaaa aatcgagtat ggcggatcat ctggatgtac agccattttg acccctacct
     3001 cttcacatgt tgggatgatt gattggagaa aataggcaaa attttctcga agtttttctt
     3061 cgtctactga tgcataggct tcaagcaagg atttgatatg agctaagcgc tcaggttccc
     3121 atcccggcaa ttcaaattca ttgctggaat gttcgatgcg cgcgacgatt tctcttggat
     3181 catctggaat atcatcagat ataaaagcta acgtggatga gccgtcttct aagcggtagt
     3241 caaggtcaga tttcacccag tcaaatacag gcataaaatt atagcagatg acttctattc
     3301 catattctgc caagtttcgg attgtctgct tatagttttc gatatactgc tcacgggaag
     3361 gtaatccaat tttaatggca tcatgcacat tgacgctttc aattactttt agtgttaacc
     3421 cacgagactc aatttcttct tttagttctt tgatcctctc cctgggccat acctctccta
     3481 ctggtatatc catcaatgtg cctacaatcc ctttgaccgc aggaatctgt ctgatttcat
     3541 ctaaggtaat cttttcttcc tgtgatccgt accatctaaa agtcatttcc atgataaatt
     3601 tcctccatgt tcttgtaagt aatcctgtaa tgtttttcgt acggcattcg gtcctgctac
     3661 catcttgatg aacatttctt ctatttttct gccaagctct gcttggtaaa gatctacacc
     3721 aaaaatttct ttatttgaca aaataggagc cattttctca tgaatatgtg atgtatcttg
     3781 cgtacccagt tgaatatcgg aaagcttatg ctgaaagtct gtcaatagtg ggtctggact
     3841 cgggatgaat ggttttcctt gatcatcaat gccaataagg tatcgaagcc aagcagcgag
     3901 agtcaatggt atgaatacaa gtgtctgcgg gtctttaact tctatttcca tatatttttt
     3961 aatcgtctca ccataacgaa tcgccacctt ttgagaggta tccgtggcga ttcgctgagg
     4021 catatcagga atatttggat tagaaaagcg cacagtaatt acttcttcca gaaagatctt
     4081 tggatcaatg atacctggag actccacaac tgggaggcct tcattgtacc cgatttcaga
     4141 aactagcagc gataaatctg gatctttcat ctcctcagct atgctcctat accccagtaa
     4201 acaacccata atagctaaag acgtatgcaa aggattaagg caagtcgtca ccttcatcgt
     4261 atctgcttta tctaccgttg cacgatcagt caagaatacc ccagcttttt cgaatttcgg
     4321 acgtccattg ggaaaatgat cttccatgat taaataatgg atgtcctctg tattgacaaa
     4381 tggagcaata ttatttcctt ttgcggtttg gaaaatcgac atatttgaaa agccctcttt
     4441 tgccaacatt ttgctaactg acaaggaagg attcggggtg atacgatcaa tcatcgtcca
     4501 tggaaacgca acaatttctt cattcgataa gtattggata aatgtatttt gtacataacc
     4561 ttccttttgc cattcttttg cgatcgttag caaagaagta cgtaattgac taccgttttg
     4621 tgaaaaatta tctgtagaga caagtgcaat cggccaagct ccagataaaa aacgtttata
     4681 aagtagcgca gcaagaatac tcattgtatg tgatggcttc tttggaccat tttttatatc
     4741 gactgcaatc ggtcctatat atttattatt tgtatctttc aatcgataac ctttttcagt
     4801 aatagcaaaa gtaactaatt gtaaactagg attttcaaag tgtcgaatca tcttatcaaa
     4861 gtgttcagaa caatctggat gacaatacag actgtcagct gtcgcagcta atatacgttt
     4921 gacgaactct ccactgcttg gcatgaccac ttcaagaatc aaatcatcaa aatcttggta
     4981 agccctttca attatttctt catcgaatgt ttcacaaaca atgacaccag tggacaattc
     5041 gcctagatcc gctaaacgtt gagcgatttc tgcatgaaat cctcgataaa gatttccgcc
     5101 accgaaatgg atccagacag gatttttttg tccattttct cttaatgatg cacggtcaaa
     5161 atgaggtatt tctacttctt tttgagataa ttcagggata aagttcctcc agttgtttaa
     5221 atcaatcatt tttcccctcc taaactaaca tattagtttt tgtattcaag tgaattttat
     5281 acaataaaaa tcgctatgtc aaccaaaatt ttactattta tacaaattta ctagttaatg
     5341 tgacatacca gattgttttt cagacctctt ctgttatact acgttcatag aaatgatttt
     5401 ggaggaataa agatgaaaag cagcttgcaa tcacaagctt atcaagcgat tcgtaaacaa
     5461 attatctatg ctgacttaga acctggaagg aaaatatctg aaaaggcact ggaggaacat
     5521 cttgctatcg gccggactcc cattcgcgaa gcattgattc aactacgtca gcaagaactc
     5581 gtgtatacga tacctcaaag tggtacgtat gtttccaaaa ttaatcttgt ttctgcagaa
     5641 aatgctcgct ttgtccgaga acagttggaa gagcaaatca tgattgaatg ttgttccaaa
     5701 ttggacacac aaacacgaat agtgctagaa acgattttag aagaacaaga aaaagcagtc
     5761 aaaataaatg acgaacgcgc ttttttccgt gcagataatt tatttcatga agcttgtttc
     5821 gaaattgcag gaagaaaaga agtttggaac tggttagatg accataatac ccatttagaa
     5881 cgtttccgct ggttacgagt gaccattcag gggcttccat gggaaacgat catggaacaa
     5941 cattatgatt tactcaaggc tttagttgat aaaaaaccag aagaagctcg atttcaaacg
     6001 ggattgcact tacacatgat gctgaaagaa caggaaactg ttactcaacg ttatcccgag
     6061 tatttccagc agtagcattt tcttgcgacc tcttctattt ttataattaa ccttcgtttt
     6121 tgagtaatct ttattaaata acaaaatatc cattgacttt gcaactccaa ctaaattaca
     6181 ataattataa ataaataatt attattggag gttttactat gtcattgatt gggaaaaaaa
     6241 tcgaagaatt taatgcacat gcttatcatc aaggagaatt tttagaagtc agtgaaaaag
     6301 atcttatggg gaactggagt attctttgct tctatccagc tgattttact tttgtttgtc
     6361 ctactgaatt agaagactta caagaacaat acagtacatt gaaatcttta ggtgttgaag
     6421 tcttttcttg ctctaccgat acccacttta ctcacaaagc atggcatgat acatcagatg
     6481 ctatcggtaa aatcgaatac gtgatgatcg gtgatccgtc tcatcagatt tctcgtattt
     6541 ttgatgtttt ggatgaagag caaggattag ctcagcgagg aacatttatt attgatccag
     6601 acggaatcgt tcaagctatg gaaatcaatg cagatggaat cggtcgtgac gctagtgcac
     6661 tgattgataa gattcgcgct gctcaatatg tacgtaccca cccaggtgaa gtttgtccgg
     6721 caaaatggaa agaaagtggc gaaacattga aaccaagttt tgatcttgtt ggaaagattt
     6781 aggtggtgga tatgttagac aaagaaacta aacaaaatct cgaacaatat ttagcactga
     6841 ttgaatctcc tattgttttt tctgttagtt tggataatag tgaaaatagt caaaaactag
     6901 ctgaatttac gaaggaaata gcagaaatgt ctcctaaaat ctcttgggaa aaaagagatt
     6961 cgatgcgcac acctagtttt tctatcaatc cagttggcaa agaaagtgga atcgtttttg
     7021 ctggtatccc cctcggtcat gaattttcct cttttttact ggctatgtta caaattagtg
     7081 gacgggcacc gaaaatcagt gaatctttga gtcttaaaat caaaaaaata acacaaacat
     7141 tgcattttga cagttatgtt agcttgactt gtcataattg ccccgacgtt gtacaggcat
     7201 tgaatatatt agctgtatta aatccaaata ttactcatac gatgattgaa ggtgggatgt
     7261 tccaaaaaga aatcgatgat aaaaaaatca tggcagtgcc aactgtgttt ttaaatggag
     7321 aagaatttag tagcggacgc atgacgatcg aacaaattgt tgaaaaaatc actggccctt
     7381 tgattgaaga agagttgttt gaaaaagaac cttatgatgt attagtaatt ggcggtggac
     7441 cagcagctag tagtgcagct atctatgcag cacgtaaagg aatccgtaca ggacttgtcg
     7501 ctgattcttt cggcggacaa gtcgttgaaa cactagggat tgaaaatatg attggtacct
     7561 cttacacaga aggtccaaaa ttgatgcagc aagtagaaag tcatgtgcgt agttacccta
     7621 tcgacattat gatgaatcaa caggccgttt ccttaaataa agagcaacat tttattaata
     7681 ttggcttagc taacggtata tcacttaaag caaaaaccgc catcatcgcg acaggtgcgc
     7741 actggcgttc tatcaatgta ccaggcgaaa aagagtttaa aaataaagga attgcttatt
     7801 gcccacactg tgacggccct ttatttaaag gaaaagagat tgctgttatc ggtggtggta
     7861 attctggtgt tgaagcagca atcgatttgg ctgggttagc aaaacatgta tatgttctag
     7921 aattcttacc agaattaaaa gcagatcaaa tcttacagga taaactagtc tctcttgcga
     7981 atgtcactgt tatcaaacat gcagcgacga aagaaatcag cggtacgaat caggtagaat
     8041 ctctctccta tatcgatcgc cgtacgatgg agatgcatac actagctgtt tcaggagtat
     8101 tcattctagt cggcttactc cctaatacgg attggctaga tggaacgatc gaaatgaatc
     8161 caagaaatga aatagtgacc gagaaaaatg gcgcaacgaa tatccccggc gttttcgcag
     8221 ctggtgattg tacagatagt ccatacaaac aaatcattgt ttcaatgggt tcaggagcta
     8281 ctgcagcttt aggagcattc gattatctga tgcgcacttg agctatgaag attgtaaaaa
     8341 gtcagagagc ggaaaaaagg atggtgacaa gaattttgtc acaatccttt ttgttttttt
     8401 gaataatcgc tttttcttct ctttttctta tatactataa gtagtaaata atttgaaaaa
     8461 aagaaaggtg actgattatg gcgcaaaatc gtatttttac gacaagtttt gcaagcgttt
     8521 atcctatgta tgtagcaaaa gcggagagaa aagatcgtat aaaagaggaa gtagatgaaa
     8581 tcatttgttg gctgacgggt tattcccaaa cagaactaga atatcaacta caaaaacaag
     8641 tgactttcga acaatttttt gcggaagccc ctgtccccaa tccttcacgt tccttgatta
     8701 caggtgttgt ttgtggtgta cgagtagaag acatcgagga taacttgatg aaagaaattc
     8761 gttatttaga taaaatgatc gatgagctag caaaaggcaa aaaaatggaa aagatcctca
     8821 gaagttgatt tttccagaga tattcttctc cttcgctcat tttgtaacat ttaatttggt
     8881 aaaatgacta gttcacgtta aaataagtca aaggaggttt tcttatatgt ttgagacgat
     8941 taaacaaaat attcaaaaat acgccttatt aagagctgct gtttatatta tttctgggat
     9001 tgcgattgtg ctaaaccctt ctgctgtttt tcattttatc ggttatctga tcaccgccta
     9061 tcttgttttg cttgggttgt tgaatctttt tgaggcttac cgttttaaaa ggaaaacagg
     9121 ttcttggagt atcggtctgt tcagtggtct ttttttcctg atcttagctc tgatcgtcta
     9181 tgcttttgca cctgcaatcg tttctatcct gccgattctt cttggattag ctgttatcat
     9241 caacagcttg ttccagttgt tcttcagcat gaatacaaaa gctaaaagtt ggagtgttta
     9301 tagtagtatt ctgttgttga ttggcggatt cgtcttattg ttcaatccat tcaaaagttt
     9361 gatgcttcta ttccaaatat tcggctttat tttgattttc atgggcatcc aggagattat
     9421 caatttcatc agaataagaa aaatgactat acgttaatca tttttagtta ttaaaataga
     9481 ccgtataaaa accaacaatc caaaaaaatc ttttggattg ttggtttttt tgtgagtata
     9541 ttttcctatt ttttcaataa tgtatgttat gctaagttcg ggctatattt tatacaaagg
     9601 aatgatgaga atggaattta ttggtatttt atgcctgata ttgatttcaa caacgattgg
     9661 ctcacatatc tcgcggagat taggtatccc agcagtgatt ggacaattac ttgttggtgt
     9721 tttgctaggc caagctggat tgaattgggt caaacctgat attctagtcc atgacttttc
     9781 ggagattggt gtgatcttat taatgttttt agctggtctg gaaagtgatt tatctctttt
     9841 gaaaaaatat ttccgacctg gtatgttcgt tgctttgctt gggatcatct tcccggttgt
     9901 ttttggctgg ttgacaggca aagcattcca agtttcggga aatgaagcga ttttctttgg
     9961 gattattctt gcggcaactt ctgtcagtat ttcagtagaa gtattaaaag aactaaacgt
    10021 agtgaataca aaagaaggat caacaatttt gggtgcttct gtggtagatg acattttagt
    10081 cgttttagtt ctaagtttca gcctatcttt tctaacgggg gaagcttcta gcaatgcttc
    10141 tttaccgctt gttttgattg aacagctaat ttattttgtt tttattttct tattagtcaa
    10201 atggattgcg cctttcctac tttcatttgc agaaaaagtg tacgcaaatt cttctattat
    10261 catcgtatcg ctagttattt gtttaggaat gtcttacgta gcggatcttg ttgggcttag
    10321 ctctgtcatt ggtgcttttt ttgctgggat agctgtcagt cagacaaagg ttaaagaaga
    10381 agtataccac aatgtagagg ctttaggata tgcagtattt ataccagtat tttttgtcag
    10441 tgtaggatta gaagttgatt tttctgactt tagtgaacaa ctactcttta tttctatatt
    10501 gacgcttgta gcgattttga ccaaattgct tggaggttat tttggtgctc agattgccgg
    10561 tttttctcaa catagttcat tgatggtcgg tgctggtatg atttcgcgtg gagaaatggc
    10621 tttgatcatt ttacaaattg gacagcaaag tcaattgatc gaaccacagt actattcacc
    10681 tttagttatc gtgattttat taagtacact tatttctcca cttgttctca aatattttac
    10741 aaaaaaagtt tatgaagtgt gagtaaatca aaaagaagtt gtgaaagaga catcgtgaaa
    10801 accgtttatt tgaaaaaagg actgtgacga taacgccaca gtccttttac tgtacttaaa
    10861 aagcaatttt ttattgataa ttttggttga ggtattgcaa tagttccgat gctcgtttgg
    10921 ttgctgaatc atcatcttct ttattttcca acatgctgac catcatataa ccttggttat
    10981 caagattgaa agcaaacaag aaactgttct cttgcccctt tacatcctgt ttttctttga
    11041 tttccgctgt accagttttc gctgccaacg gaatccctaa agcagaaaga gaatgtgctg
    11101 taccatttac atcttgcaca acttctctca gatctggcac gatcgtttgt actgctgttt
    11161 cgctgatgac attcttctta tcttttgtct ctttatctgc aatcaattta ggatagacaa
    11221 gtgtgccatt gttggtaaaa acagaataca ttgctgcttg ctggatagga gtaattagaa
    11281 gttcgccctg tccatatcca gtatcagcta gcaagatatc tgagttaaag ctatcttcat
    11341 tagaaatttg tgctggattc atactaattg gcaaatcaag gtcttcacca aaaatgaatt
    11401 tatctaagcc tgtacgaaat tttttctcac ccattttcaa cgtttcttgt gccgcatata
    11461 tattatcgga atagatcaaa gcagttttta agtctacttg tgatacatca ctactgacac
    11521 gcgttgtttt aaaagatccc caagaactgt ctttttgcca tttaagcccg ttgatcgtca
    11581 acacttcatt tggatcgata gtgccgttgt cgagaccgat tgctgctgta atcattttaa
    11641 acgtagatcc aggagcataa cctgtcgcaa atcggctgat gaatggatgt tcaggatttt
    11701 cttcataagc tttgtaatct tcttgtgaga tcccgtttgt cattttgttt ggatcatagc
    11761 ttggagagct agcaagcgca agaagatcac cggtttttgg cgttgtcgca acagttgatg
    11821 cagcttttcc tcctagactg tcaaaagcta ttttttgtgc cttcgcatcg attgtcaatt
    11881 tgatatcttt gccattttga acttcatgtt cgatcagaac ttttttctct acaccgtctg
    11941 catctgtaat gcttaatttc ccacctgttg tcccacgaag atccttatca aaagccatct
    12001 ccaaacctga gcgaccgatt tttccattac tgcttaattc tggattctta tcaatatctt
    12061 ctgctgtgat atctcccacg taaccaatca gctgagcagc tgcttcaccc aaaggataat
    12121 atctgccgtc tacttcttga atggtagctc cagctggaag ttctggcgtt gctccatcaa
    12181 tgattttcaa tgggacaaag taatcgggtt gtacccagct ttgtgaaatc gcctgattga
    12241 tagcatcttc tgttaagtcg aaggaggaag caatcgcttt gatattggct gttttttcgc
    12301 ctccatctcc aagtttactt ggaacgactc ctaattgttt tagtttgcct gttgttgcta
    12361 atggttcacc atttcgatct ataatattcc ctcttgctgc ttcttgtgtg gtcaggctta
    12421 ctttgtcatt tccttccatt tctggaaaaa ccaagttggg ttgccagttg atcgtggttt
    12481 gaccatcatt tctgtctaat gttcctttat aagaaagatc tttcaattca cctaatgagg
    12541 tattcatctt tgctttatat gaaaaactgt aagtagaatc gtctttttta tctactttta
    12601 gattcgatat ctgaagtcct ttgacatcag cagcaccgta tatattctgg tatttatcta
    12661 agatctcttt ttcagataat gcacttttat ttgccgcctt ttttgatgtc atttctgcag
    12721 ctttgttata atctcccttg ttcaaagctt ggacaaattg ctcaactgtc ttttctccag
    12781 cttctactgc ttgggtttct tgatagtgct ggtagtaaaa ataaccgcca cccgcagctg
    12841 ctattaagat cactgcgccg gcaatataag cgcctgttcg atttttgccg tgcttgtcac
    12901 ttcttttcat tttttcctcc ttctcttgct tgtcattcct ttatttcact atttatacct
    12961 gtttattcta acatatgtct ttgaggaaat ccataccaca atccagaagc acactttctg
    13021 gaaggttcgt ttggatacta ccaagtaatt tcccaaccgc tttgggtagc ttgaatattg
    13081 aagttacgtc tttcagctgc tgagagatag ctttgatcac ttgctgctgc cttctgatcc
    13141 tcccgaagtc tccttctttg tcttcccgaa atcgagcata ctggagtaaa gtattaccat
    13201 ccatcacttg ctctcctttg tttatatata cgccatctaa atctagagat ttttctgcat
    13261 cgatcttgac tccaccagga aacagttcat taacgcaatc gataaaatct tgaaatgtga
    13321 tacttgcata atagggagct tcaaatttga aattttcctt taatgtttga tttaataaat
    13381 caactccccc ataagagtaa gctgcattta tcttattcat tccgtaacct ggaatatcga
    13441 catatgaatc tctcatgata gagatcagtt ttgcttgttg tgttttctgg ttgtattgtg
    13501 caaccagaag tgaatccgag cgacctccac caatcgatct tttttcaccg catctcctcc
    13561 tcacacagca atccacttgt caggtgagga gcgagtttgt ctcatcaaat aagtcagtca
    13621 caaaaatata aagaaaaggt cagaaacctt ttcgaacaag aattctgacc tagcatcatc
    13681 tcatcgtccg agttttagca ctatacaacg taaagaaaac attcttagct attggaaaaa
    13741 gccttaatcc aacagtttct gttttaccca ttggcgactt tcgacgtttc tgggcaacag
    13801 cctatgtttg tataggagcc tcacctaaca aggttattac tatattctat ttacgagttc
    13861 atgatagact tttcctaatg attaggcaat ggaatttgaa atgaaatagt gaaatttaac
    13921 aatctttaat attttttaga aaaaaataac aaataagttg aaagaatccc gttgcaaatt
    13981 ctttcagttg caccaggatt ctttgataat tttttagttt tatgtgtttt tttatatgtt
    14041 ttttcacttt tcggaataaa tatttatttg ttaaagtaat taaacaatcc gctaatcgtt
    14101 tgatctggca tttctatttc cttaccatct aaagtaacag tagtaacgac aaaatggtct
    14161 tgcaatggcg gaacttctaa gtactgccct tgcagaaaat cattcactgt ttcatattct
    14221 tttttcattt cttttgaatc tgtcgatggt ttatagctta tttttaacat aactagtgct
    14281 cctttttatt cgggacgtgc aatcgtgaaa atttctccta ttgctgcata atcatttcct
    14341 gccaaacggc ttacagcatt caattttctt ggatcgatcc ttcctgtctt atcatcatag
    14401 actgtttcat ttaaatgata tttctgtact tctagcaaaa ataaatcagc tgttacttta
    14461 tttttattcc gtatctcgac atgttcatat aaggatgttt caaaacgaac ttttgcttct
    14521 gtcaatgctg gtactgaaat gattactgaa tcagttaaag tcaagtcagt caggtacagt
    14581 tcgctttcct cattaggcag attggctgct gttttattta cttcttctac gttgtcctca
    14641 tcaaggatat ggataacagc ttctcttgtc tcaagaatat tctttgctgt gtcttttact
    14701 gcatcttgtt ttctctggat cgccaaggat aagatgggtc gattcgaact gacgatattg
    14761 aagtaactga agggtgcgat attcactata tcttttgctg atttagtcgt tactactgct
    14821 actggtctag ggatgactga accaatcagc aacttgtaat tttcacgttc tgtcaattct
    14881 gaaggactcc gttcaaacat ggtttcgcct tctttctata aaattcgtta aaaagcagat
    14941 cttgaagaca aaatgaaaag taatgctttt ttcatcttct tagaatctgc tttaaactat
    15001 ctatcaattt ttcttttttg tcaagaatct gtgccgtgcg tgttttttag ttatttgctt
    15061 tacttgcggc ttcgacatat cttttagtga tcaattgcgg acgggtgata atagatccaa
    15121 ctacgactga aaaagcacct aattcatatg ctttctctac ttgttcagga gagtcagtat
    15181 gtccttccat aattactggg atatcgactt gttctatgat ttgattcaat aaatcaaaat
    15241 caggtgtctg cgtctttcgt gaatattctg tatagcctgc taaagtcgta gacaaaagat
    15301 caaaaccatc ttcttgcgct tgaagcgctt cctcaaaagt cgaaatatct gccatagcta
    15361 accgaccgtg ttcgtgaatc atttggacaa gttcagcagt tgttttttct gtcggacgtt
    15421 tacgagaagt tgcatccagt gcaatgattt ctgcttgcgt ctccaaaagt tcttccactt
    15481 ctttttctgt cgcagtaata aacacttctg acccatcgta atctcttttg ataatcccta
    15541 ttaccggtaa atcaacgatt cgcttgattt cattgatatc ttctgtcgta tttgctcgaa
    15601 taccaactgc tccgccttct tttgcagcca aagccattct ccccataata aaagaactgt
    15661 gtagcggctc gttttccaaa gcttgacaag aaacgacgac tccgcctttg atttgttcca
    15721 gtgtatccac aatatctcct ccagtaatgt tatataaaaa tacagcttca tataaaaatg
    15781 taaccctttt ctattcagga gacaataatg agctatttct ttcagcagac ctttcttact
    15841 aaaagaaaat tacttcaaat tcttcgtata cgaccagctt ctcttctgta aattctatgt
    15901 tcaacgcttc tttataagca tgtttaaaaa actcagcatg gactttccgc caataagcta
    15961 atgtccgatc cccttctcct tctttccaag catgctcttt cgtgacttca ctaaaaggca
    16021 agatggtcac atttatattt ttgatgatac aaactggttc attttttcca ttcaggacca
    16081 cgtctaattg accaactttt ggtaaaggct cattctcttg tttatacaga tcgtaaccac
    16141 ttgatgtacc agtctttatc ttttttacaa ctagttcgct caactcgtct gccatttttt
    16201 ctgtatcccc aaatgaaaag aaacctaatt tttctgattg ataactagga tatttttctt
    16261 ggaacttttt gacatattct tctacttgct gatacataac atccacccct ttgcttttta
    16321 taatgaaaaa accatccaga tactagtata aacaattatc tggatggtga gcataatgaa
    16381 ttattgaata ttcaagacac gcagactatc ttcaacgatt tgttttggtg ttaaatgata
    16441 acgttcataa agctgcccta caggaacgct atccgtgaat tctttctctg caccaaaatt
    16501 taatacgttc attgaagaat caccataata acgactgata ttttcgccaa atcctcctga
    16561 caaactacca tcttctaatg tgatgactaa ttcgtgtgtt tcttttaatt tatctaatgt
    16621 ttctacgtca ttttctgtga tcgttcctgg attgatcaac gttgcttcga ttcctttttt
    16681 tctaaaagct tttactgttt cttttcctaa ttcaagaaaa ccgcctaaag ctaaaattgc
    16741 tacttttcct ccattattta ctgtttgata ggctggaata ctataatcat ttgcgatagc
    16801 tgtaccatgt tctacaccat gtgtaggaat tcggattgct acaggctgcg ctgtttgttc
    16861 gaacgcccaa tctagcatag agatcatatc ctcttttgtt gctggagcaa gatatttgat
    16921 gttcgggata cttgataagt aaggaatgtc aaatgttcct tggtgtgttc ggtcactagc
    16981 tgagatcgtt ccgccaccga ctaaaataat cactggattc tcgttgatcg ctaaatcatg
    17041 tgataattga tcatatgccc gttgcaagaa agtacttgat tggaagacga ctggacgtac
    17101 tccctgagaa gccaaagcag aagcgaaagt gatagagtgc tgttcagcga tccccacgtc
    17161 aaaataatga tctggatgtt tttcttggaa tgttttcagt ccaaaggcgc ctggtatcgc
    17221 tgcattgact gcggcaatag gagctgtact tgtttgcatt ttcttatcca aataatccat
    17281 gatgatcata ttaaatgttt ctccagaagt tacttgcttt gcctccccgg tggacagatc
    17341 aaatggtaca tgccaatgat atttcatttt attatcgatt gccggctgat aaccgcgacc
    17401 tttttccgta tggacgtgaa gtacaatcgg atgatcaata tcttttactt cttcaaataa
    17461 acggatcacc gtttccagat cgtttccatt atccacgtaa cgataatcaa atcccattgc
    17521 tttaaatagg ttattgctgc ttttaccgtt ggtttgacga agctcagcta agtttttata
    17581 taaactgcca tgattctcat caatagacat ctcattatcg tttactaata cgattagatt
    17641 ggattgtaaa acaccaccat tgttcaatcc ttcaaaagct aagccaccac ttagggagcc
    17701 gtcaccgata aatgctacca catttcctga ttctttcttc agatctctcg ctttagctaa
    17761 acctgttgct aagctgatag atgtagatgt gtgccccact gtaaaatagt catgtttact
    17821 ttcatgttgg ttggaatatc cgctcacttc acggtaatgt cctttttcaa aaccattttt
    17881 tcgaccagtt aaaagcttat gaccataaga ctgatgggaa acatcccaaa cgattttatc
    17941 ctttggtgaa tcaaatacat aatgaaacgc aatcgttaat tctactacac ctagattcgg
    18001 accaacgtgc ccacctacat cgctgtcctt ttgcaagatt ttttggcgca tctcttctgc
    18061 caactgtttc atttcctcaa cagataattt tttgacatct gcggggctat tgattgcatc
    18121 caatacatgt aatactgtac tcataataca ttctctcctc cgtactatct tcttttaatg
    18181 aaaatagatt tgttacactt tatctattct actacttaga gttgactcta agtcaatagc
    18241 attttaaaaa aatttcagag aaagcttgtt atataagtag atcttcgcac gaatcaggac
    18301 tcaaataaaa accttctaca gacaattaaa aagctttgta gaaggtctcc taattaaggt
    18361 ctcatcaaga aatatgtttt tttaataggt gaagttcctg agcaatatga tacaaatgga
    18421 tgtttgcacc ttttaatgag attggataga tctttgtctt ttcagtttct aatccatttt
    18481 gatagctagc agcatcgcac aaaaccactc tttttttcgc acatagacat tcatcaggca
    18541 attcttctaa tgaacgaaat aaaataggat ttatttcagc gatgccttct tccgcataca
    18601 aatgaaattg ggttcgataa aaaaattgtt tgactgaact ttctgaaaca acaaaaattt
    18661 ctatttcctg tctccccgct tgttcactgt tgatcaaaga aagacttttg acgaattttc
    18721 gaatgaaatt ttcattccat cttagttgga tttgattttt ctttttccac tcttccaata
    18781 tttctacaat ttttccgtac agaagttgtt ctttttctga tagaagatag atcctttccg
    18841 gtaaaaatac ttgtccatct gcccacaacg tacggacaaa ttgtaaaaag gattgcttga
    18901 aaataaaatt ttctgcatcg tcgatttcag cgatactaat aatctgtaaa atcaattcat
    18961 tcagtgatag gtcattgaga acaaaatttt tataaacaac ttcgaaatct tttcttaaca
    19021 gctccatgtt ctcattggta taatttctac tgttgaacaa agaaaaaata taatagacat
    19081 cttcttcttg taagtctaga attccttttt gctcttccaa tccttgacag actaattgaa
    19141 ataacggctt cgtttctgcg cttttcttat cttcttcttt cagtccaagg ggaaatgcct
    19201 ttcttccgat tgcgatctct attcctcgta tgataaagga cttttcatct tccgaatatc
    19261 ttcttttaaa aaaatgagtc tctacataat caatcaactc gttacaagct tcttctacat
    19321 acggattttt attttcatag ccttcccaat tgacataacg tactaaagct agcaagatgt
    19381 tccgcgagtc aaattctggg ataatgattt ctttattttt caaataatca ttttctttaa
    19441 aaaaatccaa tacgattttt ttgattgtat atactttgct caaagaaata aattcaagat
    19501 cagccagttc tgtactcgtg aatataccat taaaataata acttaaaaac tttaaaaaat
    19561 aagattgacc gtacagaaac tgtgtgagct cagaaagagc aataccatgt ttgaatacga
    19621 gtttatactt atgcttctct cttacttgtt cttttataca atattctaga cactcggcta
    19681 gactttctag atcgtgaagg atcgttggtg tagtcaccct tagagaaata gctgtttgtt
    19741 cgatgtctat ttcttggaat tcaaataatt gttcacacag atacactttt ctaaatatat
    19801 ttcgctcgat gtaattttcc agcattcctg atacacgcct ccagtttttc ttatgatttt
    19861 atttaatcat atctgtaaat cgtatttttg tttccttttt atttagaaaa gccctttcaa
    19921 aaaccaataa aaaaagaaac tgggacaaaa gtcaaacaag ctcacaattt cagcctcatt
    19981 gtaggtagct ttgagccgtt tggactttta ccccagcctc tttcaagaat ggttattcaa
    20041 agatgtcagc gtctagttct ttgactacat ctttcaacaa ttggatacca gctgcgctgt
    20101 taccaaatgg atctagtgcc gggctgaaga cacctatgcc gtaacgattt ggcacagctg
    20161 ccatcaaccc gccgcctaca ccgctttttg caggtacacc aacatggacg gaaaactctc
    20221 ctgattcatc atacaaacca gcagttgtca taattgattt gacgattgta gcactttctt
    20281 cagtaatgat ttgtttgcca ttccaaggag caattccttt atttgccagc acagcagcta
    20341 attttgctat gcctgtagcg gtgacattga gggagcattg tctgaaataa gcatcgagta
    20401 tctccggtac gtctccttcg atcatttgat tacctttcat atagtaagca agagagcgat
    20461 tgatatcacc tgttcttgat tcagaatgat agatttcttc attcaatgtg atattaggat
    20521 catcacagat ctctttcata aatgacaaga ttcgctcaaa tttttcatct gcatctttac
    20581 cggcaatcaa cgaggttgtt gcaatcgctc ctgcattaac aaaaggattc attggatgtt
    20641 tgcgatgatt gatttccata ttcatgatag aattgaaggc aaaaccggtt ggttccgtgt
    20701 tgattgtttg aaagactttt tctattccgt tgtctttgat tgctaataac aatacgggaa
    20761 cttttgacat gctttcgatg gcaaagcgca catcggcgtc tcctccctca atcagttgtt
    20821 ttgtatccaa atcataaatc gccataccta attgtttggg atccacttca gctaatgctg
    20881 gaatgtaatc cgccacttgt cctgtttgat aatagtggaa attttttcca atcaattgtt
    20941 ctaattcttt tacttccatt tgaataacca gctttcattt tttatttttc tgcatgctgg
    21001 aatttatgac ggcatgcgta gatcgtaaat ggaataacta agacgataag ataagaaaca
    21061 atcagaatcg tttcataaat cccatgctgt ccagctgcga tactagcagg tggaacaaat
    21121 gagatacaaa aagcaaaaag tgaagtcaaa agacctaaac aagcaacgat tacttttaca
    21181 acttttccgc ctggaacctg ataggctctt tcaagactgt catctttaaa aaccagcttc
    21241 aaatagcccg cgaaaaacat aaagtacaac atcaggtaga ttacaacagt caatgacatc
    21301 gctgcaagaa atgaaagatt attccccccg ccgcttaatg taaagacggc tgcccagatt
    21361 gttgcaacga tcccatttgc gatcatcaaa tgagcaggaa caccgtgtgt gttttctttt
    21421 gcaaaatatt caggaagtaa tccttcttct gctgctacgt gaagtgcttt tgaaggagag
    21481 gttacccaag aagcaatttc tccgatgaca cctaaacaaa caagaatcgc aagaattttc
    21541 gcaatccatg caagatttgg atcaatgtgt cttaatagga attctaacga ttgaatcacc
    21601 cctgtattaa gagacaaacc atgttgaggt actgtagtag cgacggtcaa tccgccaaaa
    21661 gtatctaaaa tgattgccag aataaccaat acaaacattg ctaatggata atccttttta
    21721 gggttttcca tttcatttgc atgactggca gatgtttcta cgcccatata tgctaaaata
    21781 aaggaaacaa aaacaaccag cgtaggcaat ttcgaaaaat caggaatcaa tgttttcata
    21841 gacagtatcg tttgtagtgg agcgcctgaa gcgacataat ggatccctaa gccaaacaag
    21901 actaatgctg gcaacaagat accagctaca aaaccgatcc gagcaatcaa tgaagtgtat
    21961 ttggttcctt ttaactgtga gagtaaaata gcccagaaaa taatcaatag gattgccaat
    22021 ttcagatatt tattgttttg tatagcacca atacccgttg cataggataa tgcaccagtt
    22081 aagaaataca gcatggtcaa gtagccaact gttatctcaa accattggaa aaagattgcg
    22141 gcaaaaccga atcgttttcc caatgtgcga ctgacccaag tatagacacc gcctttttcc
    22201 catcctttca ccgttgccat ctctgctgcg cacaatgcca cagggataaa ccatagcaaa
    22261 ccgcctaata acaagaaaaa tactaagctg aagcctgagg tcgcgaatgt gggatattca
    22321 tataatgaaa cgaccattga gatggtcata gccaaaaagc caaagaacgt taattttttt
    22381 gcaggaattt tcgttttgct ttgttgcatg aatcttcctc ttttctattt gaatttgttt
    22441 caattgagtt tgttgccaaa gaagaaaaag tccaatcctt cttcttgttc ttcttttgta
    22501 gtagtgatcg ttgtaaagtg catcgccgat tttaaaatca ctgttgtcag cacataggca
    22561 tacacggcag taatgatgac accaatcact tgaatcccta agaagtacca gctgcttgga
    22621 ttcgttagta aatggctgtt agatgcaaag atccctatca gaatcgtacc tgtgaatccg
    22681 cccatgccat gaacacccca cacatcaagt gcatcatccc attgtttctt tttacgaaaa
    22741 tcaacagcag catgacagac gatacccgca atgatcccaa tcagcatggc actttttgct
    22801 tctacataac cggcacaagg cgtaatggct gccaatccag caacggatcc tgttagtacg
    22861 tcgacaaaat caaagccatt tccttttact tttgcaatga tcagccaagt aatcatcgca
    22921 aatgcaagag cgatgaatgt tgaaccaaat gcattgactg cttgttcatc tgctcgaagt
    22981 gcaccaccgg aattaaaacc gaaccagcca aaccaaagca gtcctgtacc gatagcagct
    23041 gccataagac tgctatgctg acttctttct cctaaaggaa tctttctttg accaagtgtg
    23101 aggatacatg ctaaagagcc gaatccagct gtcgtgtgga tgactgctcc accagcgaaa
    23161 tctctaaatc ccatctgatc caaaaatccg ccaccccata tccagtggca aacagggaaa
    23221 taaatcagca gattccaaaa aataacaagt ataatatagc cttttaaatt caatctccct
    23281 gcaaaagctc ctgtcatcaa aggaacggta atcacgataa acatcagttg gtaaagaaag
    23341 aacattaaaa atggaatcgt tgcaccatga aacatgttgg ggaagcttgt aacatgtctc
    23401 atcaaaaaga aatctgccgg gtttccaata acaccgccga tatcccgtcc aaaggccaat
    23461 ccgaatccac caaataccca cataatcgtt gttatcccaa cggagagaaa agattgagac
    23521 atgatcgtta gtatattatt cttccgtgct aatccgccgt aaaaaaaagc tagaccagga
    23581 gtcatcaggc aaaccattgc tgtacataaa atcatgaatg ctgtatctcc tgtattgata
    23641 ggtaatgtat tcattttttt cgcctccttt ctacgattac gagtataaaa gaaggtgtag
    23701 ttgttttttt cttctgtttt tttgaattaa tacttgcatt tataaaagac agacaattaa
    23761 taaaagcttg atgtgttgtg ctctttttcg tttttcacac aaataaagac aaaaaataaa
    23821 cggtcttctt tttatagaaa accgtttatt ttcgtctttt tttattttta aagatatttt
    23881 ttcataagga ataaagaata cttcatataa aatatataaa aaagaaccgc agcgagtgtc
    23941 gctacggttc tcaaatttgt tcttcatttc aacataagtt tttcttcaat ttgcttataa
    24001 tttacgtgca aagaatgaaa cgactaatac taaaatgatt gcaccgatca atgatggaat
    24061 gatagccatt cctgcaattg ttggtcccca agttcctagt aaagcttgtc caattgctga
    24121 acctactaaa ccagcaatga tgtttgcgat gatccccatt gatgatcctt tattcgtgat
    24181 tgctcctgca attgctccaa tgataccgcc gacgattaat gcccaaataa atcccatttt
    24241 aaattcctcc taactgactt cttacttctt attgtacacg tggttcgtta ttttctttga
    24301 ctttttgtgc acctttgcct acagcagatt ttgctttatc tgtttggcgt gaagcaaatt
    24361 gtcctgtgga ttttgctgct tctgttactt tgtcttgtac tgtttcttga tctttttggt
    24421 attcttcttg tgttttgatg tctgcaacat tcacattcac ttcgataaca tctaaatgtg
    24481 tcatattgtt tacttcagta ctgatcaatt ctttgatttg gttgtaaata tcttcgatgt
    24541 ctttaccgta ttctacgatc acatctagat ccacagctac ttgtttctta cctacttctg
    24601 tattgatacc tgctgttacg ttatctgtgt tgactaattt ttcagccata tttgagaaaa
    24661 atccgccatc taatgtcaat agaccatcta catctttcaa tgcataaccg atgatttttt
    24721 ggatgacttt gtcttcataa gtcaattcac cattcatcat gcggttttct cctttttcat
    24781 ttgccaaaac tgatccattt gttgtattca tgtttttgtt ttccatcttt gtttcctcct
    24841 atgatttaaa aaattgatca actattcctg actgtttcaa ataaaaaccg attcctgcgc
    24901 caattgctgt catgattatg atcaacaatg tcttgaaaaa tccaatcgtt aaccataaaa
    24961 cagctagcag tagtccaaga cccccaaaga taatagggag cttgtatgct gaaaatagtt
    25021 ctttcattat ttggccctcc tattccactc gagagtgctt gtagtctctt gtatcttctt
    25081 gttcttcata accgctgtat gtgactgcca ctttgaccgt ttcttttgtt ccgagtactt
    25141 tagttacttc ttcttcgata tcttgcatca atacacctgt tttccctact aatgaagaag
    25201 ttcgtttcaa gtctccgttg acatggatat ggattcgatt tttcgttgaa cgtatccgta
    25261 ctttaggtga atgaatgaac tcttcttcgt gtaaatggga acgtaccaac ccttcgatcg
    25321 cttttttgtc gattgttagt ttgccatctt cccgtttcat aacgaaagtt cctcttgact
    25381 ttggatagaa aagaacgact agcaagatga taatagcaag aacggcaaat actacagctg
    25441 cccagaaaat atattgttgc atgtagtaat tcgttaaagt aaagaagcga aatcgttcca
    25501 attgttcagg cataatatac ggcgcattga tcaacgcaat cgctagaaat actgaaagta
    25561 gcagtaaact catgataaca ccgattattt ttaacccctt attcattttc cacctcctat
    25621 aaacttattt ttaccctgta aataactcta ccgacaatca cagtatagat agcgaacagt
    25681 tagcatagca tcagtaaata aagcgctacc aaacattgct ggatcataac ggcgttttat
    25741 tgccagtctg atactgaaat aacaattgct tacttattct ctatttactt ttgattgctg
    25801 gctatactta aaggatatta ttcaagatta aaaattgcaa agattatgct cagttattat
    25861 tacaagattc tattt
//
LOCUS       DADGHT010000033        25516 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.033, whole genome shotgun sequence.
ACCESSION   DADGHT010000033 DADGHT010000000
VERSION     DADGHT010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.033"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(136..843)
                     /gene="deoD"
                     /locus_tag="JX887_001225"
     CDS             complement(136..843)
                     /gene="deoD"
                     /locus_tag="JX887_001225"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAX1257227.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(860..1678)
                     /locus_tag="JX887_001226"
     CDS             complement(860..1678)
                     /locus_tag="JX887_001226"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAX1257228.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            complement(1702..2868)
                     /gene="deoB"
                     /locus_tag="JX887_001227"
     CDS             complement(1702..2868)
                     /gene="deoB"
                     /locus_tag="JX887_001227"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAX1257229.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            complement(2967..3923)
                     /locus_tag="JX887_001228"
     CDS             complement(2967..3923)
                     /locus_tag="JX887_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1257230.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            complement(3923..5056)
                     /locus_tag="JX887_001229"
     CDS             complement(3923..5056)
                     /locus_tag="JX887_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1257231.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            complement(5049..6611)
                     /locus_tag="JX887_001230"
     CDS             complement(5049..6611)
                     /locus_tag="JX887_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1257232.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            complement(6823..7905)
                     /locus_tag="JX887_001231"
     CDS             complement(6823..7905)
                     /locus_tag="JX887_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1257233.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            complement(7971..8369)
                     /locus_tag="JX887_001232"
     CDS             complement(7971..8369)
                     /locus_tag="JX887_001232"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAX1257234.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            complement(8390..9052)
                     /gene="deoC"
                     /locus_tag="JX887_001233"
     CDS             complement(8390..9052)
                     /gene="deoC"
                     /locus_tag="JX887_001233"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAX1257235.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            complement(9098..10399)
                     /locus_tag="JX887_001234"
     CDS             complement(9098..10399)
                     /locus_tag="JX887_001234"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAX1257236.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            complement(10540..11556)
                     /locus_tag="JX887_001235"
     CDS             complement(10540..11556)
                     /locus_tag="JX887_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1257237.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            complement(11864..12469)
                     /locus_tag="JX887_001236"
     CDS             complement(11864..12469)
                     /locus_tag="JX887_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1257238.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12665..13588
                     /locus_tag="JX887_001237"
     CDS             12665..13588
                     /locus_tag="JX887_001237"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAX1257239.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            13647..15212
                     /gene="guaA"
                     /locus_tag="JX887_001238"
     CDS             13647..15212
                     /gene="guaA"
                     /locus_tag="JX887_001238"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAX1257240.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(15703..17334)
                     /locus_tag="JX887_001239"
     CDS             complement(15703..17334)
                     /locus_tag="JX887_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAX1257241.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(17348..19021)
                     /locus_tag="JX887_001240"
     CDS             complement(17348..19021)
                     /locus_tag="JX887_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1257242.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            complement(19034..19351)
                     /locus_tag="JX887_001241"
     CDS             complement(19034..19351)
                     /locus_tag="JX887_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAX1257243.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            complement(19376..20776)
                     /gene="lacG"
                     /locus_tag="JX887_001242"
     CDS             complement(19376..20776)
                     /gene="lacG"
                     /locus_tag="JX887_001242"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAX1257244.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            21013..21798
                     /locus_tag="JX887_001243"
     CDS             21013..21798
                     /locus_tag="JX887_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAX1257245.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            21801..22493
                     /locus_tag="JX887_001244"
     CDS             21801..22493
                     /locus_tag="JX887_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAX1257246.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(22767..23138)
                     /locus_tag="JX887_001245"
     CDS             complement(22767..23138)
                     /locus_tag="JX887_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAX1257247.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(23538..23768)
                     /locus_tag="JX887_001246"
     CDS             complement(23538..23768)
                     /locus_tag="JX887_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257248.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            complement(23862..24200)
                     /locus_tag="JX887_001247"
     CDS             complement(23862..24200)
                     /locus_tag="JX887_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257249.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            complement(25128..25244)
                     /locus_tag="JX887_001248"
     CDS             complement(25128..25244)
                     /locus_tag="JX887_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAX1257250.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
BASE COUNT         7436 a         5602 c         4499 g         7979 t
ORIGIN      
        1 ttcacaacct cttggtaaac ggtgttcaaa agcttacatt tgcaataata agtccagcca
       61 agtcaaaaac atgaggagct atttttgctt ggatgttctt attacttaat gcagggcagc
      121 tttttcattt ccttcttatt ctgctatcgc tgtttccaat cctacttcga tcatttcatt
      181 gaacgtagat tgacgttctg cagctgttgt ttcttcaccg gtgatcaaat ggtcgctaac
      241 ggtcatcaaa cttaatgtct gcacatggta tttcgcgcct aagtaataaa gagccgctgc
      301 ttccatttcc actcctaaaa cgccaagttc agctaattgg aacgtctctg tcaaatcatc
      361 tttgtagaaa gaatcttccg aaagaacatt tcctacatga accgtatagc ccttttcttt
      421 agctatctca tatgctttca gtaatagatt gaaatcactg attggaggaa aatgaaaggc
      481 ttggaaattt ttttcgatca tcgaagaact ggtcgctgca ccttgtgcta gtactaaatc
      541 acgaacatgg acgtcttttg acaatgcacc gcatgtacct actcgaatca atttctttac
      601 accatacgac tggatcaatt catgggcata gatggtggct gatggcattc ccattcctgt
      661 tccttgaaca gaaatacgtt ctcctttata tttgccggta aagcctaaca taccgcgtac
      721 ctgattgtaa caaactggat cttccaaaaa agtctccgca atatatttag ctcgcaaagg
      781 atctcccgga agtaaaatct tatcggcgat ctcgccttct ttcgcttcaa tatgcacact
      841 cattttattg ttcctcctat tacaataatg tcaatgtttc tttaaccaat gctttaaaag
      901 attgtttgac tctctgagtt gtttctacaa cttcttcatg gctcagattc gcttgcatac
      961 ctgctgctaa gttggtaata caagagattc ctaacacttt taatccgctg tgagctgcta
     1021 cgatgacttc tggaacagtc gacatcccta ctgcatcggc tcctattgtc cgagacattc
     1081 ggatctccgc aggcgtttca taagttggtc cagaatagcc catatatacg ccttctttaa
     1141 gatccaaacc tagtttttct gctgctgctt ttgctgttgc ttgatagtca ggcgtataag
     1201 cttgactcat atctggaaat ctagggccca ttgcatcttc attcggaccg atcaaaggat
     1261 tttcaccagt aaaattgata tgatcggtaa tcagcatcaa atctcctggt acaaatgatt
     1321 cgttgacacc accacatgca ttagtcacaa tgactgaatg ggcccctagt ccggccatca
     1381 cacgtactgg ataggtcact gtttgcatgg aatgaccttc atagtagtgg aatctccctt
     1441 gcatggctaa cactttcttg cctgccagag acccataaac tagctttcct gcatgcccaa
     1501 ctactgtcga aacaggaaag aacgggatct catcataaga aatcattaca gcatcttcga
     1561 tttcatctgc taattcacct aatcctgaac ctagaatcaa accaaaatca atttctttta
     1621 ctcctttatc aaggataaac tgggtcgttt cttgtaacat ctcgcttaac ttggtcattt
     1681 gctttctcct atttaaaaag attattttaa taatttcaag aagctttcgc cattttcagt
     1741 cgaagaaaca ctaaagttct cagcaatcgt tgctgaaata tctgaataat atccttgagg
     1801 caatgcccct tgttctttca tttttttact gtaaaccaat aacggtacat attctcgcgt
     1861 atgatcggta ccagtaaacg tcggatcgtt tccgtgatcg gctgtaatca ttagcaagtc
     1921 gtcttcttcc atcgcttcaa gcaattctgg aattcgtaag tcaaattctt caatcgcatg
     1981 cgcatagccg actacatccc gacgatgacc gtataatgca tcaaaatcta ctaaattggt
     2041 aaagctgatt cctgaaaaat cgtttttcat aactttcagc agctggtcaa cgccatccat
     2101 attgcttttc gtgcggacag attcagtgat tccttgtccg ttgaaaatat cgttgatctt
     2161 tccaacagca atcacgtcct ttcctgcttc tttcaaagaa tcaaggactg tgtgtccgaa
     2221 tggattcaac gcataatcat ggcgattgct tgttcgtgtg aagtctcctg gttcacccac
     2281 gtacggacgt gcaatgattc ggccaatcat atacggatca tcttttgtta tatcacgaac
     2341 gaattggcaa atccgatata attcttctaa aggaatgatt tcttcatgtg ccgcgatctg
     2401 aaggacagga tcggcagaag tatatacaat taaatcgcct gttttcattt ggtgttcacc
     2461 gtaatcgtca ataacagctg ttccgctata aggtttgtta catacgactt tacggccaga
     2521 aaattcttcg atttgtttga tcagatcatc agggaatcca ttaggaaaca cacgaaatgg
     2581 agttttgata ttcaatccca tgatttccca gtggcctgtc atcgtatctt tccctacaga
     2641 aacttcttct aatttcgtcg catagccttg atgatctttc actgattcca caccttcaag
     2701 aggacggatc gttcctaaac caagctgctc taaatgtgga acgttcaatc ctgcttcttt
     2761 cgcaatgtgt cctaatgtat cagaaccaac atcaccgaac ttatcggcat ctggtgcttc
     2821 tccaattcct actgaatcca tgacgatcag atgtacgcgt ttaaacatga ttattccttc
     2881 tttcttttta tttttattgc ctttaaaaca aaaagggcga gacgaaaaac acttcccgta
     2941 acccaccctt tttattcgct aaaagattat tttgatttga tatagttctt cccgtttgct
     3001 tttggaccag aagctttccc taagaaaaca accagcacaa tgattgtcag caaatatgga
     3061 gcaatttgca gcaatactgg cggaatcgaa gaaataactg gtaattgtgc gccaatgata
     3121 ctcaagcttt gagcaaaacc aaagaacaat gaggcaccca ttgcccctaa aggattccac
     3181 ttaccaaaga tcatagcagc catggagatg aacccttgtc caacgatcgt accagctgaa
     3241 aagttaccgg aaatcgactg agcaaaaaca gcaccgccca taccgcctaa caagccagaa
     3301 atcagtacgc ctgaataacg catagcatat acattgatac ctaatgtgtc ggcagcttga
     3361 ggattttcac caactgaacg gaggcgcaag ccgaatttcg tcttgaagat gatcacccaa
     3421 gctaggacag caatcaaaat agcacaataa gcaggtaaga atgtattttt aaagaaaatt
     3481 ggtccaatga ccggaatatc tgctaatcct gggaaagaaa aataccccag attctgcgtg
     3541 atgttatcag tttgaccttt accataccat gctttgatca agaaaacacc taaagcaggt
     3601 gccatcagat taattactgt cccgctgata atatggtcag cacgcaaact gactgttgct
     3661 actgcgtgaa tcagagaaaa taggatacct acgacgccac ccactaaaat agcgatccat
     3721 ggtgtcatag aaccaagtga tggactcatc gtcaagttga aaacgatgga actaaaagca
     3781 cccatgacca tgattccctc tagccctacg tttacgatcc cgcttcgttc agaaaaagtt
     3841 ccgcctagtg acgttagaat tagcggtgtt gaataaacca gtgtagaagt aaggatcaag
     3901 gcaattaatt cgatagtcga cattatagtt cgcccccttc atggttttga ttcgttggtt
     3961 tcgattctat tgtcgcaacg atctcttctt gttttttccc ttggaagact ttagccatga
     4021 cgaaacgaat caggaagttg atcccgacaa agaagataat caaagcaatc gatacattga
     4081 cgatctcaaa cggaacacct gctcctgtct gcatgccaag tccaccgatc ttcaaaatac
     4141 tgaacaagat cgctgataaa agaataccga ttgctgatcc agaaccaagc aaggaaacag
     4201 ccattccgtc aaatccaata gatagcgaag tcgtttgaac aaagaagttt tgatacgttc
     4261 ctaatccttc aaccacaccg ccaagccctg ccaaagcgcc agaaatgacc atcgacaaaa
     4321 cgatcgtacg tttactactc attcctgcat actcagaagc aaaaggattc aatccaacag
     4381 aacggatttc aaatcctaaa gtcgttttct tcatcagcag ccaaacgaaa ataagcgcga
     4441 tgattgctaa aaataatcct gagtttacgc gagagccgcc aaaagcttgt gttaaccatg
     4501 gtaaccgcag tgaggcattt tgactgatca tattggaaga gtccaaactt gagcgatagc
     4561 tttcaggcat cacttcatgt aaagcaaatg tgcttacgta taataagata tagttcatca
     4621 tgattgttac gatcacttca cttgttccaa aaaatgctcg aagtaaacct ggaacagccg
     4681 ctgccatcgc accagctaag gcacctaaga tcacgcataa cggaagcaaa acaacttttg
     4741 gcagatctgg aaacgcaagt gccacccaga cactgacgat ccacccgcaa agtgcttgtc
     4801 cagaaagccc aatattgaaa aacccagctg agttagctac agaaaaacct aatgctgtaa
     4861 aaatcaacgg cgttgcttgc cttaacgttt cacctatccc tctttgcgaa ccaagggctg
     4921 catctagcat agaagaataa ccttggatgg gctgaaaacc aaaagcagcc atcaatatcg
     4981 cgcctaagat caatcctaaa acaactgaaa gtacaggcac taataaatta cggaattttt
     5041 cgctgcgatc attcatgtgc gccagccccc ttttctaact cttttcgtgc ttcttctaag
     5101 gtatagcccg ccatcaatag acctaattca ttttcagatg tttctttcgg atcaacgata
     5161 ccgacaattt ctccttcatg gataacagca atacgatccg aaacatttaa aatttcttct
     5221 aattcgaaac tgatcagtaa cactgctttg tatttgtccc tttgttcgat cagacgttta
     5281 tgaataaatt cgatcgcacc tacatccagt ccacgagttg gatttgcaac aatcaacaga
     5341 tcaggatctc ggtcgacttc acgagcgata attgcttttt gctgatttcc gcctgataaa
     5401 gcttttgcgg gaacaagttc attcgttgtt cgaacatcat attcttcgat caattctctg
     5461 gcatgttcat tcattactga ataattcagc atgccgtttt tactgtaagg tttttgatga
     5521 taggtttgta gtgcgatatt ttcagataat gtcatatcta ggactaaccc gtatttatga
     5581 cggtcttctg gcacgtgtcc tacaccatgt tcagtgattt ttcggggttt tttattagtg
     5641 atgtcttccc cttttagctt gatatgtccg ctttctgcct ttcgcaaacc agtcaaagct
     5701 tggatcaact ccgactgccc gtttccatcg attccagcga taccaagtac ttcgccagca
     5761 cgaacctcta agttcaagtt tttcacggct tctaatccac gattttcttt caccactaga
     5821 ttttcaatag acaaaacgac ttcttgaggc ttcgcttctt ttttcatcgt tttgaatgaa
     5881 accgttcttc caaccatcat atcggctaat tgttgtgagg ttacgtcttt aacgttgact
     5941 gtaccgattc cttttccacg gcggataact gtacagcggt cagctactgc tttgatttca
     6001 tctaacttat gcgtaatcaa aatgatcgac ttgccttctt tgactaattc cttcatgatc
     6061 acgattaatt catcaatttc ttgaggggtc aatacagctg tcggctcatc aaaaatcagt
     6121 acatctgctc ctcggtaaag tgtttttaaa atttctaccc gttgttccat tccaactgaa
     6181 atatcacgaa cgtaagcatc tgggttgact gacaatccat actgttcaga aactttttgg
     6241 atctcttttc gtgctttttt atggtcaagc atccctgcgc gactaggctc gcttcccaac
     6301 acgatgtttt ctgttacagt aaaggcatca acaagcataa agtgctgatg gaccatccca
     6361 atccctaatt ggttggcttt ggtcggactt gtgatcttta cttctttccc acgcatcaaa
     6421 attttccctg atgtcggctc taataatccg gaaagcacgt tcatcaatgt agatttgcca
     6481 gcaccgtttt ctccaagcaa cgcatgaatt tctcctgcct ttacttgtaa attgatgttg
     6541 tcatttgcct tgaatgttcc aaattctttg gtaatattct gcatttctat gacaatattt
     6601 tcttgaacca cctttttttc acatcctaac gatttctatc tagggcaacg attgactaag
     6661 attcacgctt agtgagcgtt cttcttttga aacaaacatt acttcaggga gttgttccct
     6721 tatccaaact gtcacaaggc agcttggata aatgaacaat tcttgttcta atcaaaccat
     6781 agccttgtca aacatgtgtc taacaaggct atagaaatgg ttttagtttt cttcaggagt
     6841 ttctggaact tttacgtcac ctgaaatgat tttttctttt gcttcatcaa ctgctttttt
     6901 cgcttcgtca gaaagttgtc cttctgttag accaacaccg tcttctttca atccataaac
     6961 agtgtgttcg ccgccaggga atttaccgtc cgctgatttt tgtgccaaat cttctactac
     7021 tgttccaact gctttcagtg tagatgtcaa tgtgaagttt ttcttttcgc cgtttaatgt
     7081 gtattcgcct tcgtctgatt ggtcgcggtc aacaccgata acccaaactt ttttgtcgcc
     7141 tgattcgttc aatgattttg cttcttggaa tacaccgtta cctgtaccgc ctgaagcatg
     7201 gaagatgata tctgcgtttt gtgcatacat accttgagca attgaacgtc ctttatctgg
     7261 agcagagaag tcaccagcat attgattcaa tactttgatt tcttttccta attctttcgc
     7321 acctgcatca acaccggctt tgaatccagc atcaaaacga tcgattactt caccttttac
     7381 accgccgata aagccgacta cgtttgtttc agtcgtataa gctgctgcaa cacctgcaag
     7441 ataagaagct tcgttgtctt tgaaagttgc agatacaacg ttatctaatc catcgatgac
     7501 atcatcgata ataacaaagt tcgtacctgt attgtttgtt gcttgttctt ggatcgctgg
     7561 ttttagttta taaccaatac caaaaatcgt tttgaatcca gcattcaatg cttggtcaat
     7621 atttgggatg taatctgatt catttgaaga ttggaaatat tggaagccat catttcctcg
     7681 tgaaagtcct tgatctttcc cccatttttc tagtccttcc caagctgact ggttgaatga
     7741 acggtcgtct acaccacctg tgtctgtgat caatgctgca gttgttgtgt ctgatgagct
     7801 tttgccaccg gatgaatcag tagagccgtt gttgccgcat gcacctaaaa ataaccctgc
     7861 tgctagtgcg acagcaccta aaccaaataa ttttgctttt ttcatttctg taaagcctcc
     7921 taaaataatt gttttatttt tcaacagtca gctgactgaa tgaacatgag ttatagatct
     7981 ttttcagtaa atgcataagg cagcagtgca cgaacggtcg ttgccttcgt cacaccattg
     8041 tctcctacta gcgtaaccgg catatcaggg gaacagaatt ctgccattac ttgtcgacat
     8101 gcaccacaag gagagatagg atcgggggtg tgccccgcta cgactagatg cgtaaatgtt
     8161 ttttctcctt cagatactgc tttgaaaaaa gctgtgcgct cggcacaatt cgttaatcca
     8221 aatgatgcat tctcaatgtt gatgccttga taaatcttgc ctgattccgt tacgagacaa
     8281 gcgcctaccg gaaaatggga ataaggaaca taggctttat ctaacgcttc aatagctgtg
     8341 ttgatccatt cttgtttgag ttctgccatg agcttctcct ttgaaaaaat taatagcctt
     8401 caccagttga accagatacg attgctactc ctgcgcttgt tccgattctt gtagcaccag
     8461 cttcgatcat tgccattgct tcttcttcgt tatggatacc gccggaagct ttgacaccca
     8521 tttctggtcc tacagtttca cgcatcaaac ggacatcctc tacctttgct ccgcctgttg
     8581 agaaaccagt tgatgttttg acaaaatcag cgcctgcagc ttttgctatt tcgcaagctc
     8641 ggatgatttc ttctctatct aataacgatg tttcaataat aactttgaca agcgcacgat
     8701 cttttgctgc ttcaacaact gcttcgatat ctttttggac ttgttgatca tcctttgatt
     8761 tcaaagcacc gatattgatg accatatcga cttcatctgc accgttattg atggcatctg
     8821 ttgtttcaaa tgcttttgtc tcgggtgtgt ttgctcctag aggaaacccg attactgtac
     8881 atacggctac tggctcacct tgtaattgtt ctttcgctag cgcaacccat gctggattga
     8941 tgcagacaga ataaaaatgg tatttttttg cttcttcgat aatttgcatc acagcttctt
     9001 tagatgcgtc tgctttcaaa atagtatggt cgatcattcg gtttagttcc atttcttttc
     9061 cccttttctt taaaacggta aagtccgctt ttttccttta ttctgtgatg atgtcatgaa
     9121 tcaacgttgg cttcattgcc gattcaccaa tttcaatatt tttatataat aattcaatga
     9181 cagaagtgat ttcttcgtcg ttactataga tcgtcaatag tgactcacct tttgtcacag
     9241 tgtcaccaat ttttttatgc agtttcaatc caacagcgtg atcaatatct tcttctttgg
     9301 ttttacgccc agcacctagc atcattgcag caattcctaa ttcatttgcc acgatttttg
     9361 acacaactcc gctttgttta gcaggaagct ccattgtgta gcgtgcagtc aaaattcgtt
     9421 ctggatgttc cacgatcgct gggtctcccc cttgattttg gatcatttct ttgaattttg
     9481 ctaacgcttt acctgattcc agagcttctt gaagcaacgt tcttgcttca tcggttgtct
     9541 tagctttgcc agcaagaaca accatttggc ttcctaaggc gtagcacatt tctactagat
     9601 cttctggacc atttccttgt aatgtttcga ttgcctcgac aacttctaga ctatttccga
     9661 tagcttcgcc aagaggttct gacatatctg agataaccgc cactgtttct cggttagcca
     9721 gtttcccaat gctcgtcatg gtctttgcca gacgtcttgc atcttcgatg ttcttcatga
     9781 aagcaccgtc tccagtggtc acatccaaaa cgattgcatc tgctcctgcc gcgatttttt
     9841 tactcataat cgaactggca atcagcggaa gagaatcaac ggtcgctgtg acgtcacgca
     9901 aggcatacaa ttttttgtcc gccggtgcca agtttcctga ttgaccaatt accgctactt
     9961 tactttcatt aacaatgcgt acaaattctt catccgaaag ctcgatctga aatccgggaa
    10021 ttgcttctag cttgtctagt gtaccacctg tgtaacctag accgcgtcca gacattttag
    10081 ccactgtcac tccgacacta gctactaggg gggctaaaat caatgtggtc gtgtcaccaa
    10141 cgccacctgt cgaatgctta tctaccttta ttccttcaag agaactcaaa tcgatgacat
    10201 caccagaatt agcaatcgcc aatgttaagt tcgtgatttc ttcatttgtc atgtcttgat
    10261 aaaaaattgc catcaataat gcactgactt gataatctgg aatctttcca ttcgtatagt
    10321 tcgtgacgat gtactcgatt tcctctttcg acagctcgtt tccatccctc tttttttcaa
    10381 tcagatccac cattcgcatt gcctgatcct ccttgtcttc attcggtatt atacattatt
    10441 tttaggaaag gtaaaccact ttagtaaact ggtttactaa aaataaaaaa agcactaact
    10501 agcctttgta aatgcttaca taagcaatat accgccgagt tagccctttg tcaatacttt
    10561 tacgctctca cgaataatta attttgtttc gaacactttg ttcggaactt ttctttgagg
    10621 aaattcgatc gtatcgatca ggaaacgtgc agcataaaat ccaatatcaa aacttggctg
    10681 ctgcactgtc gtcaattgcg gaatcatgta ttctgacagc tttaatccat cgaatcctat
    10741 gactgagata tcttctggga tttttttgcc caattcatcg atcgcctgat agcatccgat
    10801 cgccatggca tcattcccgc aaaaaatagc cgtgatatct ttatgtttga gtaatttttt
    10861 tgatgcagta tatccacctt ggacagtcaa ctctccatgt tcaacaaatt tcccattaaa
    10921 aggcaggcca tgatctttca gcgcatgacg atatccgttg aaacgttctt ctaattgata
    10981 gtatccagtg gtttccttca gcatgccgat cttcgtatgg ccattttcaa taaacagcga
    11041 aacagcttga taggcgccct catattcctt tacgataagc cgtccgttat cccgacgatt
    11101 caatccgcga tcgattaaaa tgattggcat tttttgataa aaaccgctgt ctaatgcata
    11161 tttctcaggt aaaatatttg gtgtggccag caagattccg tccactgagc ggtgggaaag
    11221 ctcttgtaaa tacttgatct cattttcttg gctatgacga gaattgcata acatgatcac
    11281 atagcccaaa ggattcaaat agctctctac accttcgatc agtttggaga agaagaaatc
    11341 agtgacatca gggacgatca ttccgatggt ctttgaatgt cgattgatca catttgaagc
    11401 gaaataatcg ggcttataat gatgttcatt cacgatcgac aacacttttt ttcttgtctt
    11461 atcactaaat ctgcttcctt tgttattcaa aatctgtgag acagttgtta ctgatacgcc
    11521 tgccatttct gcgatatctc tgatggtcag cttcatccta ttggctccct tctatctaaa
    11581 ttccctatca gtgtaccaaa acccccaaga aaagaataga gaaaaaagga aagtatgttt
    11641 tttgataaaa acctccttta tctaccgact tggcagtctt ctatacaagt tctgtatctt
    11701 atttatttta tcgtaaaaaa caacgactct gttcctacta tttctttttg aagaaaaaat
    11761 agttctttgt ttttaaaaac ttctcaacaa aaaaagaact gatacgtacc cgtacatgca
    11821 cgcccagttc cactctttcg tcgctccact atttttcagc tagttattct ttcacacttt
    11881 tgatgatata atatccttta tcttttgtga cgatttctgc attaccaaat gtttcttcca
    11941 ttttcttttg cgcactcggc gctccttgtt tcttctggat cacaattgtc agtgtaccgc
    12001 ccttcttcaa ccgaggatat gcgcctgtca aaatttcatg tacaactttt tttccagcac
    12061 ggatcggcgg attgcttacg atagctgcat aggtttcttc atgaactgct tcatagatat
    12121 tcgattgatg gatatcaaca tgttcgattt ggttacgctt tgcgtttcct tgcgctagac
    12181 ttaccgctcg ttcattaatg tcgaccattt caacaaaccg ctgtgtcgca aatgccaaag
    12241 ctaacccaat cggtccatac ccgcatccca catctaagat ctttccttca tcaggtaact
    12301 cttcccaatc gaaagcatca atcaggacac gtgaaccata atccactgtt tcacgtgaaa
    12361 atacaccaga atctgttaca aattgaaagg ttctgccttt taactcaaaa gcccattgtt
    12421 caaaatcgtg cgccgtatct gggcgttcag aatagtaatg atttgtcatg tcttccatcc
    12481 ttctcatttc tttcatgaca acagtctatc cttttatgta tccgtgcgca agtcaagaat
    12541 aagactccgt ttctttctat tataaagatt atacaaaaag atcggcaatc tctcttaagt
    12601 ggtggggttt gcgtttattt tgtgttaaaa tagttccatt gatgggagaa cgcaggaggc
    12661 taatatgaat gatccaatga actactaccg tgtggcaaga gaagaatggc gagaatttta
    12721 tcgtaatggg caagcacctt tgacacaaga tgaactagat aatatcaaaa gtttgaatga
    12781 ccgcatttcc atgcaggatg ttcgagatat ctatgtacct cttgctcatc tgatttatct
    12841 ttatatgaaa gaatttgaat ctttgttctt gagtaaaggt ttatttcttc ataaatacgt
    12901 agaagtaccg ccttttatta tcgggatcgc cggaagtgta gccgttggaa aaagtacaac
    12961 agccagactg ctgcagacga ttttgtctcg taccttcaaa cgaagaaacg ttcagctgat
    13021 cacgactgac ggatttcttt atccaaatcg tatattaaaa gagcgtggaa tcatggaccg
    13081 taaaggattt cctgaaagtt atgatatgga gatgctgatc gatttcttga accgtgtaaa
    13141 atctggtcag gaagagataa aagtacctgt ttactcacat gatgtgtatg atatcattcc
    13201 agacaagtac gaattgatcc agcagcctga tatcttgatc gttgagggga tcaatacgct
    13261 tcaattacct gcgaatcagc aaatctacgt cagcgacttt tttgattttt ctgtctatgt
    13321 cgatgccgat cccgtgctga tcgaaaaatg gtatttggat cgttttggtg cgttactgga
    13381 tacggctttc caaaatccag agaattatta ttatcgtttt gctatcggag atcgtgaaga
    13441 agcctttaaa atggcaaaag atgtatggaa aaatgtgaat ttgaaaaatt tacaggaata
    13501 tatcttgcct acacgaggaa gagccgatat aattctccat aaaactgaaa atcatatcat
    13561 cgattcgatt ttcatgcgaa aatattagca ttttaaaata gtttgactat tttgagataa
    13621 aatttaaagg gataggggta ataaatttga caaacgttgc cgatatgacg aacgttgaaa
    13681 agattatcgt attagactac ggtagtcagt ataaccaatt gatcacaaga cgtattcgtg
    13741 atcttggagt cttttccgaa ttattgagcc accgcattac tgcagaagaa gtaaaagcga
    13801 tgaatccaaa gggaatcatt ctttctggcg gaccaaacag tgtatatgat gagaatgcat
    13861 ttgggatcga tcctgagatc ttcaatttag gtattcctgt attagggatt tgctatggta
    13921 tgcaattgat cacgtacaaa cttggcggtt ccgtagagcc tgctaaaaac cgcgaatatg
    13981 ggaaagcctt gttagaagta acaagcgatc aagctgtctt gtttaaagaa acaccaaaac
    14041 aacaaacagt atggatgagc catggtgact tggtaactaa agttcctgaa ggctttgaaa
    14101 cagtcggaac aagcaaagat tgtccgattg cttctatcca agacacaaca cgtaattttt
    14161 atggtatcca attccatgca gaagtacgtc attccgaata cggaatcgaa ttgctgcgcc
    14221 actttgcctt tgatgtttgt cactgtgaag gtaactggac aatggataac tttatcgata
    14281 tgcaagtaga aaaaatccgt gaacaagttg gtgacaaaaa agtcttgctt ggtctttcag
    14341 gtggcgttga ttctagtgtc gttggggttc ttttacaaaa agcgatcggt gaccaattga
    14401 catctatctt tgttgaccac ggtctgctac gcaaaggcga agcggaacaa gtaatggaaa
    14461 gtctaggcgg aaaattcggc ttgaacatca tcaaagtcaa tgcaagagat cgcttcttag
    14521 acaagttgaa aggtgtatct gacccagaac aaaaacgtaa aatcattggg aatgaattcg
    14581 tatatgtttt tgatgacgaa gcaacaaaac ttgctggtga agaaggcgtc tctttcctag
    14641 cacaaggaac gttgtatact gacgttatcg aatctggtac agaaacagca cagacgatca
    14701 aatctcacca taatgtaggt ggactgccag aagatatgca atttgaattg atcgaaccat
    14761 taaacacatt attcaaagac gaagtccgtg aattagggac tcagttaggc atgcctgatt
    14821 caatcgtttg gcgtcagcca ttccctggtc ctggtcttgg tattcgtgtt cttggcgaaa
    14881 tcactgaaga caagctagaa atcgtacgcg aatctgatgc tatcttgcgt gaagaaatcg
    14941 cagctgctgg acttgaccgt gatatctggc aatatttcac tgttcttcca gggatccgct
    15001 ctgtcggtgt tatgggtgac ggacgtactt acgactacac agtcggtatc cgtgctgtaa
    15061 cttcaatcga cggaatgacc gctgactttg cccgtatccc atgggaagtc ttgcaaaaaa
    15121 tctctgtacg tatcgtaaac gaagtagccc acgtcaaccg tatcgtgtat gacatcactt
    15181 ctaaaccacc agcaacagtg gagtgggaat aaagagccaa cataatatgg agggggaatc
    15241 cctataaatc aacattcttc aatagctaaa atgcttgatt ttcattaaaa ataagatggt
    15301 tccctaccaa aagagactat aatataagtt aatttgtttc attcttatca taaaaagaag
    15361 ttctcgaaaa acgaactgtt ttccgagaac ttttttctat ccatctaagt gctcaaatca
    15421 tattcacgac ggaattctaa ggttaccctt tcttaaacaa actttatgtt atctgcacaa
    15481 ctttttgcaa ttttttcatt gcttcttacg aaatcgttga actctcttta gcataataca
    15541 aagtgtagat gaagtctggt gctttactcg ttttggtaaa aatgactgga aatcgtttct
    15601 ggttattttt ggcaaaggcg aggtgcaggt tcgattcctg ccttctacgc taacgatgtg
    15661 gctgaaggga acctccgatc ttgaatcgaa acgatccgca gtctattgtt tcaccaatga
    15721 aacaaaatca acgttcgtcc aagcatttcc tgaagccttg ctataaaccc caatttcaca
    15781 aacacctgtt gtaattggaa tgtctttgat tgtaattttt gtccattcac ttgttttaac
    15841 aaccgcagta tttagttccg ctccaccata atttttgata tataactgat tagtatcaaa
    15901 ctctccccca gacattacat aggcactcaa tgtgtaagtt cctttgctta tgccactaac
    15961 attttgataa gctgatgcct cgtatgcttg atcctgccaa aaagttagtt tgtagtcccc
    16021 aaaaaaagtg cccgcttccg ttttgatcgt acccttagcg gttccttgtt gaaaccaggt
    16081 ttgccaattg gaaggactgg tcgttggtcc atcgctttcg aaacttgcat ttttaactag
    16141 atttatttgc gcccctgctt gtttaaacgc acgcaagctt ggcaaggcgt ttccagcaaa
    16201 atcaaacatc gcttggttgt cccattcgtt tcccatagtg gattgaacac tgagataatt
    16261 catacctgct tgtgttgccc aactcacatt tccgttgtac caaagaggtt cccaatagaa
    16321 gaagcccgcc ccgcgattat tcggtactgc ctgaatccga tcggcaagat ccagcaaata
    16381 ctctgcttgt cctgtcggtg ttggttcata tccccccgca gctgcttcgg cttcaccaaa
    16441 agcatttggc atagtatcgg cattcgctgt tgtatgccca taagctgttt caactacgat
    16501 cacttcttta ccataccgtt ggctgatcgc attcatattg gtttgaagtt cattcattga
    16561 accgtgccaa tacggataat acgacactcc aattaaatca aatgacacac ctcgactcgt
    16621 gatttcatca aaccaccaag taaatgctcc tgtatcgcca ccatcagcta agtggagcat
    16681 tactggagtt gttttaggtt gagtgtctcg aacagcttgg ataccagact tcaaaaaagc
    16741 agccaatcga tcaaattctc ccccgccttc tccccaagac ttgccataag gccagagcat
    16801 tccgctattc agttcattgc cgatctgaac catatcagga taaacgtcca gctgcttcat
    16861 ttccgacaga acgttctttg tatagtcgta caatgccgta ttcatttctt caaaggtcag
    16921 accttgccat gctttaggaa gattctgttt cccaggatca acccaaaaat cactgtagtg
    16981 aaaatccagc agcaccttaa gtcccagatt ttttgctcgt tttgcaaggt caatcgtcgt
    17041 ttccagatca tttgtccctg ctccataact ttctccatta ctattataag gatcctgcca
    17101 caaacgcagt cgaacatagt tgacaccatt attttttaaa atctctaagg catcttttga
    17161 aatatcgtct tcataatatt ttgcaccaga tttttccata tctgacagga tcgaaatatc
    17221 tgctccgcga ataaattcgc tggcagatgc ttcaacagtt tttgaaacag cccccaaagc
    17281 ccctaacaca gctgcaaata aaacagcttt acgcaaccaa attcccattt tcattatggc
    17341 tcctccttta ttgaaattgg ttcagaataa actgaacagc tttttcagga tctctcgtta
    17401 atccgatata ttctgctcct tttgtcgcaa ccagcttgat tcctaagcga tcggtgtctt
    17461 ctttgatatc atcatagtaa gaattgactt gcggtgctaa gaccaccata tcaaaatcct
    17521 gcagcatttc gtaatgagaa ccataagcac ccgccattgc actgatcggt gctttcgatt
    17581 cagatgcacc tttttttaaa gcattagcta acatcgcact tgtccctgcg ccagcacaaa
    17641 gtaccaacac attgatttct ttatttgcat cgctgataac ttgactcgct gccacaggta
    17701 cttcctcacg tacatcggca gaagcacctt cctcggttgc gatcacctct gctttttgtg
    17761 cttctttctc tactaagaca gcatcgtatg ctttgcaaaa tggtagatag atcaggaagt
    17821 caacgacgat tagaaccgct gctagaacaa aagctaagat acccatgccc gttcctagaa
    17881 ccaaaccgat cggtgctgga gttgcccaag gcaaaacgta cataaagctg ttcatgccca
    17941 atacatcgac aaaaaacttg aacaggcaaa cgtttacaac aggtgttaac aaaaatggaa
    18001 taaaaaaata agggttcaaa atcatgggtg ccgcaaatag caatggttcg ttgacagcga
    18061 aacttactgg aataaaggaa gctttcccaa ctgccttcaa ctgcttagac ttagcaaaga
    18121 gtaggaagat aaaaggaaca accaatgttg ccccagttcc tcccatagtt cctacaaaat
    18181 tccctaaacc caccgtcagt actttagaag cttgttcacc ggaattgaac aattgcagat
    18241 tggtttccac attggcatag ataattgccg caattgccgg ctccacgatc gacggtccat
    18301 gaacaccgac aaaccaaaac agcgccatcg ctccccagat aatagcgatt cctaagtacc
    18361 cgtcagctgc tgtaaatagc ggctgcagca ccgtaatgat tgcttctgca aatgagattt
    18421 ggaagatttg tcgaatgcct aaatcaatta aaacggccgc aaatactgaa aaagagaaag
    18481 gaaaaatatc tcggaaggtt tgcgaaatcg ttccaggaac ttctttaggc attttaatgg
    18541 taatatcttt cagcacacaa aacttatata aattaactgt taaaaatgca gcgacaaagg
    18601 aagccagtag tccctttgtc cccatatatt ccgttgaaaa tccaccttca atcggagaga
    18661 cgcttaacaa caggaaactt accacagagg ccagcatcac agaggtggtg ttgattactt
    18721 tgtttttcgg taagcgacga ttcatcgaat cagccaagca gcgagcagtg gttgctgaaa
    18781 cgagtaaccc tacaacaccc atcgaataat tatagacttt ccatagccat gtggagacag
    18841 attcaggcca ttggtaacca aaaatctcag gaaccgcagc aatcaaaatg aaaatgcttg
    18901 aaaataaaat agctggcatc gctgttaaaa atccgtcacg aacggctcct aaataactat
    18961 tacgtgagat tttttcaaaa aatggtttcc ctttttcgat ttgtttaatg attccatcca
    19021 tagcgttctt ctcctatcct tgattctgtc tgtacagtac aataaagtct tgaatcagat
    19081 ctctcagcaa taaagtggtc attaaatgat cctgcccatg gataaaaatg aatcccatct
    19141 ccatctcttt cccagatgct tcttccgcta aaatttttgt ttgcgaatta tgtgcaaggg
    19201 ttaaattttc gtcggcttct ttcaacgccg aatcaacatg ttcaaagttt ccttgtctta
    19261 cttctttcaa taatttcaat aatgtactgc gagcgtcgcc tgaatatgca acgatctcaa
    19321 aaccaagcat ttgtaattcc tctttattca tcttttcttc ctccattatc acttattaaa
    19381 taatcgtttt ggtttcactg accaacttgt accagtaagc tgattctttt gggtaacgct
    19441 tctgggtttc aaaatcaaca taaaacaagc catacctttt gttataccca tttgtccatg
    19501 agaaaagatc cataagcgac cacaaaaaat accccttcac atttaccccg gctgttatcg
    19561 ccttgcttaa ggattccaaa tagactctca aatagtcgat tctcggctga tccataataa
    19621 tgccatcttc aaactgatct ttatacccca tcccgttctc agtgatatag attttgttgt
    19681 aatgtgggta atcgctttta attcgcagca acaagtcata tagaccttct ggataaatca
    19741 gccagtccca atcagttcga ggaattcctt ctttataaat acgttctccg attcccttca
    19801 ctttataaac agaggtccct ttttcacccg taccgttatg atggattgca ttttctccat
    19861 cgtaagcttt gacaaaatgg cattggtagt gattgatccc taagtagtca ttacgcgtgg
    19921 atgctttttt caattcaacg aaatcttctt caggaaaatg atagctggcc tgatttgctt
    19981 cacatatctc atcaagagca gtcaaggttt cagttgaata atagcctaaa taggtagcat
    20041 ctaataagaa acggatcgac aatgcatcgt ctaaaaaggc agcatgctta tcttccggcg
    20101 cgtctgttgc cgcatatttc gtctctaatg agtgaactac accaatttca cccggaagtt
    20161 cgttttcttt gaaatagttc actacacggg catgagcaac catcatatta tgaagacagg
    20221 cgacgatctt tgtaaaatca tatttgattc ctggtgggaa aacacctaac aaatattgat
    20281 tggttgcaac tggatagatt tcattaaagg tactccacac cttgacttct ttgaattcat
    20341 gaaaacaaaa aatggcatag gaaacaaatg cttctattgt ttctcgattc aaaaaatctc
    20401 catggtcaaa caaacgttta ggggtatcaa aatgatgcaa cgtcacaaac ggcgttacgt
    20461 ttcttttctt acattcttcg aacacacgat gataaaaagc gattccttct ggatttggtt
    20521 tcccagctcc atcaggaaaa atgcggctcc aagcaatgga taatcttaga ccatttacac
    20581 caaaacgttc acacaattca atgtcctttg catattgatg ataaaaatca cttgccggat
    20641 cgggactgaa tcgcccttgt tcctctaaaa agtcatccca agcaacagcg cctttgccac
    20701 cttccttagt ggctccttca acctgatagg ctgctgtggc tccgccaaaa ataaaatctt
    20761 ctggtaattt aagcatgtac atctctcctc aaatctataa tcagttttcg ctctttctaa
    20821 ctgattgcat tgtaaacgca tccaaaacat ttgtcaacaa aaacaaacac aaataatcat
    20881 aaaaaccaga aaacagcaat aaaatctatt gtaacaaaca taaaaaccac cctaaatgtt
    20941 tacttttgtt cgaattagat tgactgttgt ccgtttatat gatagattat ccttaaatta
    21001 gaggtgaaga caatgttgaa aaaagaaaga ttgcttacta tcgtagaaat ggtcaataaa
    21061 aaaggaatcc ttaccgttaa tgaaatcatc aatcaattag atgtttctga tatgaccgtt
    21121 cgcagagatt tagatgaatt agaaaaatcg ggcaagctgc tgcgtgtcca tggaggggct
    21181 caaagtcttt cctacacttt agatcaagaa ctttctcaca ctgaaaaagc cactctgcag
    21241 attcaagaaa aaaaagaaat tgctgccaca gcagcctcct tgattcacga gggagaaacg
    21301 attttcttag gaccaggtac aacaatcgaa ctattggcga cgcatttact gaacaagaaa
    21361 attcggatca ttacaaataa ttatccagtt tttgatattc ttgctcaagc agatggacca
    21421 gaaattctac tgattggcgg tgatttccgg aaaaataccg gcgcatttgt cggaccgatc
    21481 accaacgaca atttaagaag actaaagttt acaaaagcat ttatcagttc aaatggcgtt
    21541 cacaacgaag cgatctctac ttacagtacc gaagaaggag aagcacagca gatcgctcta
    21601 aataattccc gtaagaaata tctactcgtt gataataaaa aattcaatcg agatgatttt
    21661 tatgtgtttt ataatttgca tgatttcgat ctgctcatta cggatcgcca gatctcgcgg
    21721 gaggttcaag agcactatgc acaatatgtc gatctgcaaa ttgctgattc aaccgaaaat
    21781 accactatag gagcgtaact atgaaaggga ttatatttga tttcaacgga acaatgtttt
    21841 tggactctca tctgcatgaa gctgcttggc tgcatatgat acatgatcat acaaaagatg
    21901 gtttatcaga cgaggatatt ttaaaaaata ttcatggtcg gacgaatacg gagattttga
    21961 aacatttcat ttcagagcat ttgaccgcct ctgagatcgc cgtattgtca gaagaaaaag
    22021 aaagctatta tcgtatgctt tgcttgcaaa atgaaaacga gcttcagttg acaaaagggc
    22081 ttgaagcgac tcttgaccag ctgactgacc aacagattcc attaacgatt gccacggcta
    22141 ctgtcaaaga gaatgttgct ttttattttg atattttcga tttagcccgc tggtttgact
    22201 gggacaagat tgtctatgac gacggctctt tccctgggaa accgcaaccg gatatttttc
    22261 ttaaagcggc agacaaactg agcttagctc cggctgattg tcttgttatc gaagatgctt
    22321 actcaggatt acttgctgcc aaacgtgcgg ggatcggaac aattattgca attgatccat
    22381 tcggtaaaaa caaaacagta tttgaacagg cacagctaaa taaagatgga accatcaaag
    22441 attttactgg tttttggaca gagcacctgt ctgccacatc cgttaattct taaacgattc
    22501 aactaactac caaagaaaag caactgaaat gcacacctcc ttttataaaa aactgccagt
    22561 gaaacgacat gaaagataca ctgctatatc cttagtgaaa tatagcagtg tatctttgac
    22621 tttttcattc ttttaaccat atgacgcgtt catctctatc tataattaac attaaaaata
    22681 gtgttttcac attatttctc aaaccaatct taaaaatcat caggagtact tttttgatat
    22741 acttttatta atgctgggcg taatggttaa aagatttcca ctagttcctc tccaccaagc
    22801 tgagttgaaa aatgcttatc tgtaaacaac atagacaaag aggaaataaa cgtttccgta
    22861 tctttctctg tcccaaggat attaattaat tttcctacta ggtaagtatc attaaactta
    22921 agatctgcct tcacatcaaa agttttgata aaagctttta tcatgcgtac aattttgtct
    22981 ttatcgccat aattgatttc accactcata tcaatatagt cactaatccc tgaagaaata
    23041 atggcaactg cttcttcttt cgccttatca gataattcat ttaatgactg ggattgattg
    23101 atgacttctt gagttttatc tgttacgtaa tctctcatta tcctatcggc atactccgca
    23161 aagtaatctt gaaaaaattc ttctacaggg taaccaactt cgttttccca accaggagaa
    23221 atttcattat cagtacttat taaatctatt aaaaaccaac ccgttctctg agtgttgatt
    23281 ctataatatt tttaatttcc tatataaatc aaaaatatta tagaatcaat aagctaatta
    23341 agaaacaaac tttagaaact ctagaagaac ttctgaattt atatagaagt gtgtagctac
    23401 ttactaaata tacaaaagtt aaaataaaat actctggata ctctttatac tgcattaaag
    23461 ttagtaatat taacagcaaa gatatcgaaa aaacaataac ataatatgtg tcaaaatttt
    23521 tcataataag aactccctta ctgttgcata ctaacataat ccaaaaactc ttctacttca
    23581 gctaaagaca ttccactttc tttagtccaa aaaacagttt tttctatcga tccttctctg
    23641 taaactgtaa atgtcggagt cgagttaatt gagtagcgac tcttgaattc tttccactca
    23701 ttttcatctt ctctaacttt tgctacattc acgtaataaa tattttcttt tcccttttct
    23761 accagcatat cgaatagctt cctgcttttg atgatcgatt tcttgtgcta catctagtaa
    23821 attttcatca atttctatat cataaagtat ttcactagtg tctacatcca caatatatac
    23881 tttttatcag tagcaatttt tgagtaatcc gttaaaatga tctcagtctc gtcactttca
    23941 tcagtataaa tatacgttaa caatgaactc accttttcaa tcggtgttag ctctaagcct
    24001 actgtatttt ttactattga gtcattattt accaccataa cttcgtactg tatataccat
    24061 cctatttggt ttccatcaat atcagtaatt ggctcactag ctaatggagt ctccggaaca
    24121 atattttcct gatatttctt aaactcttct gtagcacgaa aaaggttatc atgttcctca
    24181 cttgaaactg gttgagtcat agaaaatgtt acttggctaa acagagggaa aataaacact
    24241 acaatcaaca aagtataaaa aaaagccctt ctttttcatt ttttatcttc caatcacaaa
    24301 ttgaaaaact tattcctgca actttgagtc tagtatcaca atcgactgac tacaactatt
    24361 catttacatt ctactttaag ttcctcctta accattaatt ttattaaaga tacttgtaat
    24421 agtgattctc acaaaatttc atgaaaaata ctttattact gtatctaaaa ttccaataca
    24481 caacttatcg actattatct gaaaaccaaa acttattatt ccttgatgtt attctagcaa
    24541 tagtaactgc ttttttattt ttttgcatat tttttcggcg ttacttttta aagttaactt
    24601 tttcgacaaa tagaaagaga tacgaatcac tgattttttt gaagaaaaga aatggagtga
    24661 gctgaacgtt agagatattg ggagctttcg taactgctta ttaaacgata atggttattt
    24721 gcaaccgtat tgctcgcttc tacatgaaat atttcatgaa atatttcgca aaacctttga
    24781 ttatgtagtt acgtttccat tcttgactaa aaatgtttca aaaacgaaca aaggtgttaa
    24841 aaggtaaagt gatcaatact actggtcaaa ataagaggtt gaaagggaat tgaaaaataa
    24901 ctacagataa tacttttata aacgtacgtg ctttgtggtt ctgtagttaa ctatataact
    24961 ggaattaggg aatggtatca atttgaaaag aaagattcta ccaatttatc atatgttaaa
    25021 aatggaaaat caacagcagt tctttcggaa accttacaca aaaaccgatt attgaaaata
    25081 gccgaaaaac gtttttcggc tattttttta attaagtttc cttcttctta ccttttccca
    25141 ctattccgtt tcacatcttt gatgatcttc agcgcacgtt ttcgtgtttt gatatttggg
    25201 cttttcaagc ggcggtatgc acttgagata tctgtttttt ccatatggac gacccacttt
    25261 cttctttgat tgtagtcatg ctaaaaaaca caaatcgaaa caattacgat ttgtgtttta
    25321 aatggtatca aaagttaaaa tgaaagtcaa cttgttaaaa cagtcgatca gactagctga
    25381 ttgactccta tctctggaaa taaattttca ttattacgtt ttagctacct aaaaaaggcc
    25441 ctcttgtccg ttaactttaa tatctattgt tatagctagt ttacctattg aacgtactgt
    25501 gtgttcgata gaacac
//
LOCUS       DADGHT010000034        25441 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.034, whole genome shotgun sequence.
ACCESSION   DADGHT010000034 DADGHT010000000
VERSION     DADGHT010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25441
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.034"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(79..765)
                     /gene="gpmA"
                     /locus_tag="JX887_001249"
     CDS             complement(79..765)
                     /gene="gpmA"
                     /locus_tag="JX887_001249"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAX1257251.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(937..1518)
                     /locus_tag="JX887_001250"
     CDS             complement(937..1518)
                     /locus_tag="JX887_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1257252.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(1651..2334)
                     /gene="rpiA"
                     /locus_tag="JX887_001251"
     CDS             complement(1651..2334)
                     /gene="rpiA"
                     /locus_tag="JX887_001251"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAX1257253.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            2653..3066
                     /gene="rpsL"
                     /locus_tag="JX887_001252"
     CDS             2653..3066
                     /gene="rpsL"
                     /locus_tag="JX887_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAX1257254.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            3150..3620
                     /gene="rpsG"
                     /locus_tag="JX887_001253"
     CDS             3150..3620
                     /gene="rpsG"
                     /locus_tag="JX887_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAX1257255.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            3714..5801
                     /gene="fusA"
                     /locus_tag="JX887_001254"
     CDS             3714..5801
                     /gene="fusA"
                     /locus_tag="JX887_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAX1257256.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            5973..7160
                     /gene="tuf"
                     /locus_tag="JX887_001255"
     CDS             5973..7160
                     /gene="tuf"
                     /locus_tag="JX887_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAX1257257.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            7567..7875
                     /gene="rpsJ"
                     /locus_tag="JX887_001256"
     CDS             7567..7875
                     /gene="rpsJ"
                     /locus_tag="JX887_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAX1257258.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            7906..8535
                     /gene="rplC"
                     /locus_tag="JX887_001257"
     CDS             7906..8535
                     /gene="rplC"
                     /locus_tag="JX887_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAX1257259.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            8563..9186
                     /gene="rplD"
                     /locus_tag="JX887_001258"
     CDS             8563..9186
                     /gene="rplD"
                     /locus_tag="JX887_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAX1257260.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            9186..9476
                     /gene="rplW"
                     /locus_tag="JX887_001259"
     CDS             9186..9476
                     /gene="rplW"
                     /locus_tag="JX887_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAX1257261.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            9515..10348
                     /gene="rplB"
                     /locus_tag="JX887_001260"
     CDS             9515..10348
                     /gene="rplB"
                     /locus_tag="JX887_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAX1257262.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            10391..10669
                     /gene="rpsS"
                     /locus_tag="JX887_001261"
     CDS             10391..10669
                     /gene="rpsS"
                     /locus_tag="JX887_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAX1257263.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            10692..11039
                     /gene="rplV"
                     /locus_tag="JX887_001262"
     CDS             10692..11039
                     /gene="rplV"
                     /locus_tag="JX887_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAX1257264.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            11053..11709
                     /gene="rpsC"
                     /locus_tag="JX887_001263"
     CDS             11053..11709
                     /gene="rpsC"
                     /locus_tag="JX887_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAX1257265.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            11712..12146
                     /gene="rplP"
                     /locus_tag="JX887_001264"
     CDS             11712..12146
                     /gene="rplP"
                     /locus_tag="JX887_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAX1257266.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            12136..12324
                     /gene="rpmC"
                     /locus_tag="JX887_001265"
     CDS             12136..12324
                     /gene="rpmC"
                     /locus_tag="JX887_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAX1257267.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            12349..12615
                     /gene="rpsQ"
                     /locus_tag="JX887_001266"
     CDS             12349..12615
                     /gene="rpsQ"
                     /locus_tag="JX887_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAX1257268.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            12673..13041
                     /gene="rplN"
                     /locus_tag="JX887_001267"
     CDS             12673..13041
                     /gene="rplN"
                     /locus_tag="JX887_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAX1257269.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            13078..13386
                     /gene="rplX"
                     /locus_tag="JX887_001268"
     CDS             13078..13386
                     /gene="rplX"
                     /locus_tag="JX887_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAX1257270.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            13414..13953
                     /gene="rplE"
                     /locus_tag="JX887_001269"
     CDS             13414..13953
                     /gene="rplE"
                     /locus_tag="JX887_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAX1257271.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            13972..14157
                     /locus_tag="JX887_001270"
     CDS             13972..14157
                     /locus_tag="JX887_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAX1257272.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            14193..14591
                     /gene="rpsH"
                     /locus_tag="JX887_001271"
     CDS             14193..14591
                     /gene="rpsH"
                     /locus_tag="JX887_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAX1257273.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            14623..15159
                     /gene="rplF"
                     /locus_tag="JX887_001272"
     CDS             14623..15159
                     /gene="rplF"
                     /locus_tag="JX887_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAX1257274.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            15320..15676
                     /gene="rplR"
                     /locus_tag="JX887_001273"
     CDS             15320..15676
                     /gene="rplR"
                     /locus_tag="JX887_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAX1257275.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            15697..16197
                     /gene="rpsE"
                     /locus_tag="JX887_001274"
     CDS             15697..16197
                     /gene="rpsE"
                     /locus_tag="JX887_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAX1257276.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            16212..16391
                     /gene="rpmD"
                     /locus_tag="JX887_001275"
     CDS             16212..16391
                     /gene="rpmD"
                     /locus_tag="JX887_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAX1257277.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            16435..16875
                     /gene="rplO"
                     /locus_tag="JX887_001276"
     CDS             16435..16875
                     /gene="rplO"
                     /locus_tag="JX887_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAX1257278.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            16875..18170
                     /gene="secY"
                     /locus_tag="JX887_001277"
     CDS             16875..18170
                     /gene="secY"
                     /locus_tag="JX887_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAX1257279.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            18232..18879
                     /locus_tag="JX887_001278"
     CDS             18232..18879
                     /locus_tag="JX887_001278"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAX1257280.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            19070..19288
                     /gene="infA"
                     /locus_tag="JX887_001279"
     CDS             19070..19288
                     /gene="infA"
                     /locus_tag="JX887_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAX1257281.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            19321..19437
                     /gene="rpmJ"
                     /locus_tag="JX887_001280"
     CDS             19321..19437
                     /gene="rpmJ"
                     /locus_tag="JX887_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAX1257282.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            19455..19820
                     /gene="rpsM"
                     /locus_tag="JX887_001281"
     CDS             19455..19820
                     /gene="rpsM"
                     /locus_tag="JX887_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAX1257283.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            19848..20237
                     /gene="rpsK"
                     /locus_tag="JX887_001282"
     CDS             19848..20237
                     /gene="rpsK"
                     /locus_tag="JX887_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAX1257284.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            20317..21255
                     /locus_tag="JX887_001283"
     CDS             20317..21255
                     /locus_tag="JX887_001283"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAX1257285.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            21283..21663
                     /gene="rplQ"
                     /locus_tag="JX887_001284"
     CDS             21283..21663
                     /gene="rplQ"
                     /locus_tag="JX887_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAX1257286.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            21935..22774
                     /locus_tag="JX887_001285"
     CDS             21935..22774
                     /locus_tag="JX887_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAX1257287.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            22750..23619
                     /locus_tag="JX887_001286"
     CDS             22750..23619
                     /locus_tag="JX887_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAX1257288.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            23609..24406
                     /locus_tag="JX887_001287"
     CDS             23609..24406
                     /locus_tag="JX887_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAX1257289.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            24609..25355
                     /gene="truA"
                     /locus_tag="JX887_001288"
     CDS             24609..25355
                     /gene="truA"
                     /locus_tag="JX887_001288"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAX1257290.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
BASE COUNT         8263 a         4692 c         5478 g         7008 t
ORIGIN      
        1 agttggcagg agaaaaccgt ttatacgaaa aaagggactg tgacaaatcg tgtcacagtc
       61 ccttttttat agtgtttttt ataggtagta ttttttagca actgttaagt catcatttaa
      121 ttcataaaca agtggttgac ctgttggaat ttcaagatcc atgatgtctt cgtcagagat
      181 accttcgata tgtttagcta gggcgcgtaa tgagttacca tgtgcagcta ctaaaacagt
      241 tttgttgtct agtaatgctg gagcaatttc atcttgccag aatggcaaag cgcgttctaa
      301 tgtcactttc aagttttctc caccaggaat atcgcgtttg tctaacattg cgtaacgacg
      361 gtcatttgct gcagaacctt cgtcagtttc ttccattaat ggaggaagag tatcgtaaga
      421 acgacgccag atgtgcactt gttcgtcgcc gtatttttca gctgtttctt ttttgttcaa
      481 accttgtaat ttaccatagt gacgttcgtt taagcgccat gatttgattt gtggtaccca
      541 aagttgatct gaatattcta agatcaagtt acatgttttg attgcacgag ttaaaacaga
      601 agtgtaagca acatcaaatt cgattccagc ttctttgatt ttgcgtccgc cttcttttgc
      661 ttcttcgatt ccttctggtg ctagatttac atcagcccaa ccagtaaatt ggttcaatgc
      721 attccattca ctaagaccgt gacgagaaaa aactaatttt ggcatgttta gctctccttt
      781 taagataggt ttatatttct gaaattttca gttctgtttt attgtacaat tttttggaag
      841 agatttccat cgaaaaatta gataagattc tatgagaaaa caagtagaga atataaaaaa
      901 acgaacagtg cccacgcaac tgttcgtttt taggtattag atgcataatt gctcgatttc
      961 tttttcaggt aaattgatat atttataaca tgttccaact gaaacaccgc attttgaaga
     1021 aataaattgg atcgtttctt ttttttcata atagagacgt cggatttttt tgatcgtttt
     1081 tgcatcgatt tttggtcttc cgccgatttt tcctttttta cgagcttcat ctaatccaac
     1141 taatgtacgt tctttgatca atgcgcactc catgtttgct aggttttcca ttaattggaa
     1201 atagattttt cccatttcgc gcgtatcgat tccttcatca agactaatca agtgcagccc
     1261 gcgatctttg aataattgcg tgagttctgt taattgccgc gtagatttgc ctaatcgatg
     1321 aagttggcaa atgactagtg catcgccttg ttgcatgtca gcgatcactg actccaaatg
     1381 aacagcagta gaatcatttt gttccacttc atatgtctca tggaaaattt cttgacaacc
     1441 aaagtcagat aattgatcaa cctgagttgt taaatcaacg tcatttatgg ttgtgcgtgc
     1501 ataaccaata attttcatgg tgattccttt ctagcagtga ttttctaact ggatataaca
     1561 gtaaaaatgt agcataaagt acgtcaaaaa gatagttttt tcgcaaattt tccgctgtct
     1621 ttttttattg gatgatcaag cagtttttct ttatttacga cggattgcgt caagaatctc
     1681 aacgcctttt tctgagccga caactacttt agaaaccatg tttaggaaaa gcccatgttc
     1741 tactacccca acaagttcat ctaaataggt agctaagctt tctggctgtt cgatgacttc
     1801 tagatgcaga tcaatgatgt aatgaccacc atctgtggtt aagacttctc cgttttcgtc
     1861 tgtacgcaag acgggttgga atcttttttc ttcaaaaata tgaagtagct gttgggagcc
     1921 ataagggatc acttcaactg ggagtgggaa cttcccaagt ttatcgacta atttagaaga
     1981 atcaacgatc caaatcgttt cttttgagta cgtagcgact attttctcga aaagcaaagc
     2041 agcgccgccg cctttgatcc cttgaaaatc agcactgatt tcatcagcac cgtctattgt
     2101 caaatcgact acggggactt catcaatact ctttaacggt attcctaatt tttccgcttg
     2161 ttcttttgtc gcatttgaag tagtaactcc tgtgatacgt aaaccttctt cacgcatacg
     2221 gcgaccaatc tcttctacca tataataggc ggttgaaccg gtcccgagac ctacgatcat
     2281 cccgtccttt acgaatttcg cggcttcaat gccagctaat tgttttaaat tcatctttgc
     2341 gtccaccttt ttttagtttg agcatcgtgc tttcctcact attttagcgt gatttacggt
     2401 aaaaagatac cattcttttt tattccaata aagctttttc aaaaaaaatt gcatctcttg
     2461 ttgacatgtt ttttcattcg tgatattcta acaaaggtgc tttatctaca ggtttctgtg
     2521 aagaaacgtg ctgactgttt atcaaagcat atttgataag gatgcagaca ttgcatttat
     2581 tttttatcac aaaaaaagaa ccacctggat gtgtggaact agacgcaaat cgtgggaagg
     2641 aggaaacaag gaatgcctac aattaaccaa ttagtacgta aacctcgtaa atcaaaggtg
     2701 gaaaaatcta attcacctgc tttgaacaaa ggatataaca gctttaagaa aactcaaact
     2761 aacgtaaact cacctcaaaa acgtggggta gcaactcgtg tgggtacaat gacacctaaa
     2821 aaaccgaact cagctttacg taaatatgca cgtgttcgtt tgtcaaactt aattgaagtt
     2881 actgcttata tcccagggat tggtcataac ttacaagaac acagtgttgt attattacgc
     2941 ggtggtcgtg taaaagactt accaggggta cgttaccata tcgttcgcgg tgctttagat
     3001 actgctggtg ttaacgaccg taaacaaagc cgttctaaat acggaactaa aaaacctaaa
     3061 gcttaatttt aattattaaa caaatgaaac ttgcttctac tatatagaag taattactat
     3121 gaacaatatt tcggaaggag gagttacgga tgccacgtaa aggtcctgtt gcaaaacgtg
     3181 atgttttacc agatcctatt tataactcaa aattagtaac tcgcttgatc aaccgtgtaa
     3241 tggttgacgg aaaacgcggg attgcagcta acattatcta taatgccttt gacttgatca
     3301 aagaatctac aggtaacgat ccattagaag tgtttgaaca agcaatgaaa aacgttcaac
     3361 ctgttcttga agttaaagca cgtcgtgttg ggggttcaaa ctaccaagta ccagttgaag
     3421 ttcgccctga acgccgcgtt actctaggtc ttcgttgggt agtaaactac gctcgcttgc
     3481 gcggtgaaca cacaatggaa gaacgcttag caaaagaaat catggatgct gcaaacaaca
     3541 caggtgcttc tgttaaaaaa cgtgaagaca ctcataaaat ggctgatgcc aaccgtgcgt
     3601 ttgctcacta tcgctggtaa gattctctct gtttggtcgg cttttataag tcgacctcag
     3661 atagtgtcct tatttttagc aactagatag taaagagagg agaaacaagg agaatgacca
     3721 gagaattttc tttacaaaac actcgtaata tcggtatcat ggcccacatc gatgctggta
     3781 aaacgactgc tactgaacgt atcttgtact atactggtaa aatccataaa attggtgaaa
     3841 ctcatgaagg agcttcacaa atggactgga tggaacaaga acaagaacgt ggtattacga
     3901 tcacttctgc tgctactaca gcacaatgga agggtcaccg aatcaacatc atcgacacac
     3961 caggacacgt agacttcaca gttgaagttg aacgttcatt gcgtgtactt gatggtgctg
     4021 taactgttct tgatgcacaa tcaggtgttg aacctcaaac tgaaacagtt tggcgtcaag
     4081 caacaactta tggtgtacct cgtatcgtat ttgcaaacaa aatggacaag atcggtgctg
     4141 acttcttata ttcagtatca actttacatg accgtttgca agcaaacgct cacccaatcc
     4201 aattaccaat tggtgcggaa gacgacttca caggaattat cgaccttgta acaatgaagg
     4261 ctgaaatgta tacaaacgat cttggaacag agatcgaaga aacagaaatt cctgaagaat
     4321 accgcgaatt agctgaagaa tggcgcgaaa aattggttga agctgtagct gaaactgatg
     4381 aagaacttac tttgaaatac ttagaaggtg aagaaatcac tgaagctgag ttaaaagaag
     4441 gtatccgccg cgcaacagtt aacgtagaat tctacccagt actatgtggt tcagcattta
     4501 agaacaaagg ggttcaatta ctattggacg ctgttcttga ttacttgcca tcaccgttag
     4561 atatcccagc tatcaaaggg attgacccta aaactgatga agaagtagaa cgtcctgcag
     4621 acgacagcgc tcctttctca gctttagcat ttaaagttat gactgaccca ttcgtaggtc
     4681 gtttaacttt cttccgtgtg tactctggtg ttttacaatc aggttcatac gtacaaaacg
     4741 caacaaaagg caaacgtgaa cgtgttggtc gtatcctaca gatgcatgcc aactctcgtt
     4801 cagaaatctc tgaagtttac gctggagata tcgctgctgc tgttggtttg aaagacacaa
     4861 ctactgggga cacactatgt gatgaaaaga gtctagttat tcttgaatcc atggaattcc
     4921 cagaaccagt tatccaagtc gctattgaac ctaaatcaaa agctgaccaa gataaaatgg
     4981 gtgtggcttt acaaaaacta tctgaagaag atcctacttt ccgtgctgaa acaaacgtgg
     5041 aaacaggcga aacaatcatc gctggtatgg gtgaacttca cttagatatc atcgttgacc
     5101 gtatgcgtcg tgaattcaaa gttgaagcta acgtaggtgc gcctcaagta tcttaccgtg
     5161 aaactttccg tgctggcact caagccgaag gtaagtttgt acgtcagtct ggtggtaaag
     5221 gtcaatacgg tcacgtatgg attgaattta caccaaatga agaaggtgct ggtttcgaat
     5281 ttgaaaatgc gatcgtcggt ggggttgttc ctcgtgaata cattccagct gttgaaactg
     5341 gtttgaaaga tgctatggaa aatggtgtct tagctggcta tccattagta gatatcaaag
     5401 ctaaacttta cgatggttca taccatgatg tcgattcaaa tgaaactgcc ttccgtgttg
     5461 ctgcttctat ggcattacgt gcagcagcta agaaagctaa tccagtaatc cttgaaccaa
     5521 tcatggctgt agaagttgtt atccctgaag attatttagg tgatgttatg ggtcacgtaa
     5581 ctgctcgtcg tggacgtgtt gaaggtatgg aagctcgcgc tggcggccaa caagttgttc
     5641 gtgcgatggt tccacttgct gaaatgtttg gttatgctac aactcttcgt tctgctactc
     5701 aaggtcgtgg tacatttaca atgacatttg accactacga agatgtacca aaatcagtac
     5761 aagaagaaat cattaagaaa aacggcggaa aagctgaata atttcttaaa accggatagt
     5821 cctgcaaaga gattatccaa agagactata tttttaatat agtttcgtgt aaaataatta
     5881 tcgatgatat gggcatgtgg tgtaccttgt gtacatcata tacctatcag acaaataaaa
     5941 aatatattgt atttttagga ggacatttta aaatggcaaa agaaaaattt gaccgttcta
     6001 aaccacacgt taacattggt actatcggac acgttgacca tggtaaaact acattaacag
     6061 ctgcaatcac aactgtacta tctaagaaaa acggcggcca agctatggct tacgatcaaa
     6121 tcgatggtgc tccagaagaa cgcgaacgcg gaatcacaat ctcaacagct cacgttgagt
     6181 atgaaacaga tacacgccac tacgctcacg ttgactgccc aggacacgcg gattacgtta
     6241 aaaacatgat cactggtgct gctcaaatgg acggagctat cttggtagtt tctgctgctg
     6301 acggcccaat gcctcaaact cgtgaacaca tcctattgtc tcgtcaagtt ggtgttcctt
     6361 acatcgttgt attcttgaac aaagtagaca tggttgatga cgaagaatta ctagaattag
     6421 ttgaaatgga agttcgtgac ctattaacag aatacgaatt ccctggtgac gatgttcctg
     6481 tagttgctgg atcagctttg aaagctctag aaggcgacgc ttcatacgaa gaaaaaattc
     6541 ttgaattaat ggctgcagtt gacgaataca tcccaactcc agaacgtgac aacgacaaac
     6601 cattcatgat gccagttgaa gacgtgttct caattactgg acgtggtact gttgctacag
     6661 gtcgtgttga acgtggacaa gttcgcgttg gtgacgaagt tgaagttgtt ggtattgctg
     6721 aagaaacttc aaaaacaaca gttactggtg ttgaaatgtt ccgtaaattg ttagactacg
     6781 ctgaagctgg agacaacatt ggtgctttac tacgtggtgt tgcacgtgaa gacatccaac
     6841 gtggacaagt tttagctaaa ccaggtacaa tcacacctca tacaaaattc tctgcagaag
     6901 tatacgtgtt gacaaaagaa gaaggtggac gtcatactcc attcttcact aactaccgtc
     6961 cacaattcta cttccgtaca actgacgtaa caggtgttgt tgaattacca gaaggaactg
     7021 aaatggttat gcctggcgac aacgtaacaa tggaagttga attaatccac ccaatcgcta
     7081 tcgaaaacgg tactaaattc tcaatccgtg aaggcggacg tacagttggt gccggtgtcg
     7141 ttacagaaat caaagcttaa ttcacttaag ttttaaagta aagcaacatt tattcggacg
     7201 taatcgctcg gaacgaaggt cttaggatct ttgttccgag cttttttatt tattgcagga
     7261 tcaggaaaaa agacaggagt attataaata gaagaaacac gaaataaaag agtcagtatt
     7321 ttctaaatga aactttatga aaacaaaatg ttttttacaa gaaaaagcct tgctttgtga
     7381 gtttatatat attataatga caaaggtgcg tttactttag tgaattgcac agacgtaatc
     7441 agaatgattt cgtcggctaa gaaacgagag gttgcgacac gcccggacgc tttgccacga
     7501 acgagcgtga cggaaatttt cgtggagcta tgtctacttt tcaaaatagg cgaaggaggg
     7561 aacaagatgg caaaacaaaa aattcgtatc cgtttaaaag cgtatgaaca ccgtatttta
     7621 gatcaatcag cggataaaat cgtggaaact gcaaaaagaa ctggagctag cgtgtctggt
     7681 ccaattccat taccaactga acgcagtctt tacacaatca tccgtgcgac tcataaatac
     7741 aaagattcac gcgaacaatt cgaaatgcgt acacacaaac gtcttatcga cattgtgaac
     7801 ccaacaccaa aaactgttga tgctttgatg aagctagact taccatctgg tgtaaacatc
     7861 gaaatcaaat tataaaacta aaacaaaaat aatggaggtg tactcatgac caaaggaatc
     7921 ttagggaaaa aagtgggaat gacacaaatc ttcactgaat ctggtgaatt aattccagta
     7981 actgttgtag aagctactcc aaacgtagta ctacaagtga aaacaatgga aacggatggc
     8041 tacgaagcta ttcaagttgg ttaccaagat atgcgtgaag ttttatcaaa caaacctgcg
     8101 aaaggtcatg ttgcaaaagc aaacacggct cctaagcgct tcattcgtga attcaaaaat
     8161 gttgagctag gagaatatga agtaggaaaa gaaattacag tagatgtttt ccaagcagga
     8221 gacattattg atgtaacagg tactacgaaa ggtaaaggat tccaaggggt tatcaaacgc
     8281 cacggacaaa gccgcggacc aatggctcac ggttctcgtt accatcgtcg tcctgggtca
     8341 atgggtccag ttgcacctaa ccgtgtattt aaaaacaaac gtcttgctgg ccgtatgggt
     8401 ggcaaccgcg taactatcca aaacttggaa gttgtacgtg tcgatgcaga aagaaatgtt
     8461 atcttgatca aaggtaatgt tcctggagct aaaaaatctt taattactat caaatcagct
     8521 gtgaaagcta aataattgta ggaagaaagg aggaactaag gaatgccgaa tgtagcatta
     8581 ttcaaacaag atggaagcca aaacggtgaa atcacactta acgaagaaat cttcggaatt
     8641 gaacctaatg aaagtgttgt ttacgatgca atcgtaatgc aacgtgcgtc attaagacaa
     8701 ggaacacacg cggttaaaaa ccgtagcgct gttcgcggcg gcggacgtaa accatggcgt
     8761 caaaaaggaa caggtcgtgc acgtcaagga tctatccgct caccacaatg gcgtggaggt
     8821 ggcgtagtct ttggaccaac accacgttct tacagctaca aacttcctaa aaaagttcgt
     8881 cgtttagcaa tgaaatctgt attgtcagaa aaagttgctg aaaacaactt ggtagcaatc
     8941 gaaggcttga acttcgacgc accaaaaaca aaagaattca aacaagttct tgctaactta
     9001 tctatcgact ctaaagtatt ggttgttcta gaaaaaggta acgactttgc tgctttatca
     9061 gcacgtaact taccaaacgt ttctgtagta acttctgata atgtgagtgt gctagacgtt
     9121 gtatcaaata caaaagtgtt agcaacacaa actgctctta ctcaaattga ggaggtgctt
     9181 gcataatgaa cttactagac gtaatcaaac gcccagtgat cactgaaaaa tcaatgcttg
     9241 ccatggatga caagaaatac acttttgaag tggacactcg cgcaaacaaa actttagtaa
     9301 aacaagcggt agaagctgct tttgacgtta aagtcaaaaa cgtgaacatc gtgaacgtac
     9361 gtgcgaaatt caaacgtatg ggcaaatatg caggatatac aaaaaaacgt cgcaaagcga
     9421 tcgttacatt gactgaagat tcaaaagaaa tccaattatt cgaagctgct gaataagcac
     9481 taatagataa ctcattaaat taggagggaa aaacgtggcg attaaaaagt acaaacctac
     9541 ctcaaatggt cgtcgtaaca tgacaggttc tgattttgct gaaatcacaa catcaacacc
     9601 tgaaaaatca ttgttacaac cattgaaaaa ccatgctgga cgtaacaaca acggccgcat
     9661 cactgtacgt catcaaggtg gcggacacaa acgccaatat cgcgtgatcg acttcaaacg
     9721 taacaaagat aacgttgttg caactgttca aacgatcgaa tatgatccaa accgttcagc
     9781 taacatcgcg ttagtacact atgaagatgg agtgaaagct tacatcttag cacctaaagg
     9841 actagaagtg ggtatgaaac ttgtttcagg tccagaagca gatatcaaag tcggaaatgc
     9901 tcttccatta gaaaacattc cagttggtac tgttatccac aacattgaaa tgaaacctgg
     9961 taaaggtgga caattgatcc gttctgctgg tacaagtgct caagtacttg gtaaagaagg
    10021 caaatacgta ttgatccgct tgaactctgg tgaagttcgt atgatcttag ctgcatgccg
    10081 tgctacaatc ggttctgtag gtaacgaaca acacgaatta atcaacatcg gtaaagctgg
    10141 acgctctcgt tggatgcgta aacgcccaac tgtacgtggt agcgtaatga accctaatga
    10201 tcacccacac ggtggtggtg aaggtaaagc tcctatcgga cgtaaagcac cagtttctcc
    10261 ttggggtcaa ccagctcttg gttacaaaac tcgtaacaaa aaagctaaat cagacaaact
    10321 tattgttcgt cgtcgcaaaa ataaataatt actttgacca tgtgtcgcac attttgagag
    10381 gaggttcacc atgggtcgta gtttaaagaa aggacctttt gtcgatgagc atttaatgaa
    10441 aaaagttgaa gctcaagcag gggttgaaaa gaaaaaagtt atcaaaactt ggtcacgccg
    10501 ttcaacagtt ttcccaagtt ttgttggata taccatcgca gtttatgatg gacgtaaaca
    10561 tgtaccagtt tacatccaag aagacatggt aggacacaaa ttaggtgaat ttgcacctac
    10621 aagaacttat cgtggacatg ctgctgacga taagaaaacg aaacgctaat ttgaggggag
    10681 gataaatcca aatggcagaa caaatcacat cagctaaagc aactgcaaaa acagttcgca
    10741 cttcacctcg aaaagcccgt ttagtaattg accttatcag aggtaaaagt gtcgcagatg
    10801 caatttcaat cttgaaattc acaccaaaca aatctgctgg aatcattgaa aaagtattga
    10861 tgtcagcagt tgcgaatgca gaaaataact ttgacttaga tgttgaaaac ttggtagtaa
    10921 gcgaagcttt tgttaacgaa ggacctacaa tgaaacgttt ccgtcctcgt gcaaaaggat
    10981 cagcttctcc aatcaacaaa cgtacaagtc atatcacggt agtcgtatca gaaaaataag
    11041 gagggataat cagtgggtca aaaagtacat ccaattggaa tgcgtgtagg catcatccgc
    11101 gactgggatg ctaaatggta tgctgaaaaa gagtatgctg agttcttaca cgaagattta
    11161 agaatccgta aatttatttc aactaaactt gctgatgctg ctgtatcaac agttgaaatc
    11221 gaacgcgcaa caggtcgcgt aaacatttca attcacacag ctaaaccagg tatggttatt
    11281 ggtaaaggcg gttctgaagt cgaaagccta agaaaagaat taaacaaatt aactggtaaa
    11341 agaatccata tcaatatcgt ggaaatcaaa aaaccagatc tagatgcaaa attagtaggt
    11401 gaaggaatcg cacgtcaatt agaaaaccgt gttgctttcc gtcgcgctca aaaacaagcc
    11461 atccaacgct caatgcgtgc tggcgctcaa gggatcaaaa ctcaagtatc tggtcgtcta
    11521 aacggagcag atatcgctcg ttcagaagga tactcagaag gaactgttcc tcttcatact
    11581 ttacgtgcgg acattgatta cgcatgggaa gaagcagata caacatacgg aaaactagga
    11641 gttaaagtgt ggatctatcg tggagaaatt cttccaacta aaaaaaacac tgagaaagga
    11701 gggaaataat catgttagta cctaaacgtg taaaacaccg tcgtgaattc cgcggaaaaa
    11761 tgcgcgggga agctaaaggc ggaaaagaag tagcattcgg tgaatacggt ttgcaagctg
    11821 ttgattcaca ttggatcaca aaccgccaaa tcgaagctgc tcgtatcgca atgactcgtt
    11881 acatgaaacg tggtgggaaa gtatggatta aaattttccc tcacaaatct tatactgcca
    11941 aagcaattgg ggtacgtatg ggttctggta aaggggcacc tgaaggatgg gttgcaccag
    12001 taaaacgtgg taaaatcatg tttgaaatcg caggcgttcc tgaagaagta gctcgtgaag
    12061 cgttacgtct agcttctcac aaattaccaa tgaaaactaa gatcgtaaaa cgtgaggaaa
    12121 tgggtggtga atcgaatgaa ggttaaagaa atcagagaat taaccactgc cgaaatgctt
    12181 gatcaagaaa aacaattaaa agaagaattg tttaatctta gattccaatt agcaacaggt
    12241 caattagaaa acactgcacg tattaaagaa gtacgtaaat cgattgcacg catcaaaact
    12301 gtgttgcgtg aacaagctaa gtaattatgg aaggaggcca ttaagcgtat gactgaagga
    12361 agaaatcaac gcaaagttta tcaaggtcgc gtggtttcag acaaaatgga taaaacaatt
    12421 accgttgctg tcgaaacaaa gaaaaaccac cctatctatg gcaaacgcat gaactattct
    12481 aagaaataca aagtgcatga tgaaaacaac acagcaaaag ttggcgacat cgtgagaatt
    12541 atggaaactc gtccattatc agctacaaaa cgtttccgtt tgttggaagt agtcgaagaa
    12601 gcagttatta tctaataaca cgagattttc ctatatagat tgaatgcaaa atctgaaagg
    12661 aggatacaca acgtgatcca agcagaaagt cgtttaaaag tcgctgataa ctcaggcgca
    12721 cgtgaaattt tgacgatcaa agtccttggt ggatctggtc gtaaaactgc taacatcggt
    12781 gatgtgatcg ttgctacggt taaacaagca acgccaggtg gggttgtcaa aaaaggtgac
    12841 gtcgttaaag ccgttatcgt tcgaacaaaa tcaggagctc gtcgtacaga cggttcatat
    12901 attaaatttg atgaaaatgc tgcagtgatt attcgtgatg ataaaagccc tcgtggaaca
    12961 cgtatctttg ggccagttgc acgtgaacta cgtgaaaaca acttcatgaa gatcgtttca
    13021 ctagcaccag aagttttata atcttgagac acttatcaaa ggaggtgcga aacagttatg
    13081 tttgttaaaa aaggcgataa agttaaagtt atcactggaa aagacaaaaa caaagaaggc
    13141 gttgtactag cagcgttccc gaaaaaagat aaagttattg tcgaaggtgt aaatgtcgtt
    13201 aaaaaacacc aaaaaccttc tcaagctgct cctcaaggtg gaattgttga gatggaagcg
    13261 ccaattcatg tttctaacgt gatggtggtt gactctactg gtgtagctgg ccgagttggc
    13321 tacaaagaag tagacggcaa aaaagtccgt gtttctaaaa aaaccggtga agttttagat
    13381 aaataaaagt ttaaggaagg agggtcttac tgaatgaacc gcctaaaaga aaaatatctt
    13441 aaagaagtaa ctccatcatt gatggaaaaa tttaactata gctctgttat gcaaacacct
    13501 aaagttgaaa aaatcgtcat caacatgggt gttggtgatg cggtatcaaa cgctaaaaac
    13561 ttagataaag cagttgaaga attaactttg atcactggtc aaaaaccaat gattacaaaa
    13621 gctaaaaaat caatcgctgg attccgttta cgtgaaggaa tgccaattgg tgcaaaagtt
    13681 acattgcgcg gagaaagaat gtacgaattc ttagacaaat tggtttctgt ttcactacca
    13741 cgtgtacgtg acttccatgg tgtaagtaaa aaagcctttg acggtcgtgg aaactatact
    13801 ttaggtatta aagaacaatt gatcttccca gaagtagatt atgatttagt agataaagta
    13861 cgtggtatgg acatcgttat tgtaacaaca gcaaactctg atgaagaatc tcgtgagttg
    13921 ttgacacaat taggcatgcc attccaaaaa taattaaagg aggcgaacta cgtggctaaa
    13981 aaatcaatga ttgctaaaaa caaacgtcct gcaaaatttt caacacaagc ttatactcgt
    14041 tgcgaacgtt gcggacgtcc acattcagtt tatcgtaagt tccatctttg ccgtatttgc
    14101 ttccgcgaac ttgcctataa aggtcaaatt cccggcgtga agaaagctag ctggtaaaaa
    14161 gtaaattcgc ataagaagga ggtaaaagat caatggtcat gacagatcca attgcagatt
    14221 ttctaactcg tatccgtaac gcaaacatgg ttaaacatga gtctttagaa gtacctgcat
    14281 caaaaattaa acgtgacatc gctgaaatct tgaaacgtga aggtttcgtt cgtgatgttg
    14341 aatacatcga agatgacaaa caaggcgtga tccgtgtttt cctaaaattt ggtaaaaacg
    14401 gcgaacgtgt tatcacaaac ttaaaacgta tctctaaacc aggtttgcgt gcttatgtca
    14461 aagctgacga agtaccaaaa gtattgaacg gtttaggtat cgcaatcatt tcgacttctg
    14521 aaggtgttgt cactgataaa gaagctcgtg aaaaaaatat cggcggcgaa gttatcgctt
    14581 acgtatggta atcaagtaga atctacaagg aggtgtcttt aagtgagccg tatcggaaat
    14641 aaagtcgttg ttatccctga aggagtaaca gttactcaag acggaaacaa cgttacagtt
    14701 aaaggaccaa aaggtgaatt gactcgtact ttttcagcag atatcaaaat gaatatcgaa
    14761 ggaaacgaag taactttcac tcgtccaaac gacagtaaag aaatgaaaac aattcatgga
    14821 acaactcgtg cgaacttcaa caacatggtt gtaggtgtca gcgaaggttt ccaaaaagcg
    14881 ttagaactaa tcggggttgg gtaccgtgca caattacaag gatcaaaact tgtattgaac
    14941 gttggttact cacatccagt agaaatcaca ccaccagctg gagtaactgt tgaagtacca
    15001 gctaacacac aagtaattgt taaaggtgcg aacaaagaag aagttggcga attagctgca
    15061 aacattcgtg gaactcgtcc tccagaacct tataaaggta aaggtattcg ttatgttggc
    15121 gaatatgtac gccgtaaaga aggtaaaact ggtaaataat cgtttagaaa aattgcatag
    15181 aagccagcag caggaaaaag gcatttggct gaagtttacc ttcaaaaaaa tacattttta
    15241 cttgtgccgc agcttctatt tttcgaaacg tatttactgc ttgaaatagt agtacaataa
    15301 aaataaagag gtgacaattg tgattacaaa accagataag aacaaaacac gtcaaaagag
    15361 acatcgtcgt gtacgtaaca atatctctgg tactgctgag cgcccacgct tgaacgtttt
    15421 tcgttctaac aaaaacatct acgctcaaat tattgatgac gtagcgggtg taacgctagc
    15481 aagtgcctct accttggata aagaaatttc aggtggaaca aaaacagaag cagcacaagc
    15541 tgtcggtaaa ctagttgctg aacgtgcagc tgaaaaaggc attaaagtag tagtctttga
    15601 ccgtggtgga tacctttacc atggccgtgt gcaagcttta gctgaagctg ctcgcgaaaa
    15661 tggactagaa ttttagaaga aggaggaata ccattcatgg tttatatcga tccaaaacat
    15721 ttggaattag aagaccgcgt tgttgcaatt aaccgtgtaa caaaagttgt taaaggtgga
    15781 cgtcgtctac gttttgctgc tttagttgtt gtcggtgaca aaaacggaca cgtagggttt
    15841 ggtacaggta aagctcaaga agttcctgaa gcaatccgta aagcaattga agatgcgaag
    15901 aaaaacttag ttgaagtacc tatggttggt tcaacaatcc cacacgaagt aatcggtgct
    15961 tttagtggtg gtagaatcct aatgaaacct gctgtagaag gttctggggt tgctgctggt
    16021 ggaccagttc gtgccgtatt agaattagct ggggtagcag atatcacttc taaatcttta
    16081 ggctcaaata caccaatcaa cgttgttcgc gcaacagttg aaggtttgaa acaattgaaa
    16141 cgtgcagaag aagttgcaga acttcgcggc aaatcagttg aagaattaat cggataagga
    16201 ggacaacaat aatggctgaa ttaaaagtta ctttaaaacg cagtattatc ggacgtcctc
    16261 aaaaccaacg cgatacagtt aaagcgttag gtcttacaaa gattaacagt tcagtggtta
    16321 agccttctaa tgaagcaatt aaaggcatga tcaatactgt ttctcaccta gtggacgttg
    16381 aagaaattta atttagaaaa atcataacta gaacattaag gaggtgccaa acctatgaaa
    16441 cttcatgaat taaaacctgc tgaaggttca cgccaagtac gtaaccgtgt tggtcgtggt
    16501 acttcatctg gtaacggaaa aactgccgga cgcggacaaa aaggacaaaa agctcgttca
    16561 ggcggcggtg tgcgtttagg atttgaaggg ggacaaacac cattgttccg tcgtttacca
    16621 aaacgaggat tcacaaacgt gaaccgtaaa gactatgcag tcattaatct tgatgtattg
    16681 aaccgctttg aagacggagc tgaagtaact cctgttgctt tagttgaagc tggaatcgtg
    16741 aaaaacgaaa aagctggaat caaagtatta gctaatgggg aactaaacaa gaaattaact
    16801 gtgaaagcag caaaattctc taaagcagct caagaagcaa ttgaagcggc tggtggatca
    16861 atcgaggtga tctaatgttt agactattaa aagatgcttt taaagtaaaa gacattagat
    16921 cgaaaatcct atttactgta tttgtgttgt ttgtatttcg cctaggtgca catattactg
    16981 taccaggcgt aaatgctgct tcattgcaaa acctttcttc tttgccattt ttcaacatgt
    17041 tgaacttggt aagtggtagt gcgatgcaaa acttttccat tttctcaatg ggggtttcac
    17101 catacattac tgcttctatc gtcattcagc ttcttcaaat ggacatcgtg cctcgatttg
    17161 ttgaatggtc gaaacaaggg gaagttggtc gtaaaaaact gaatcaagcg actcgatatc
    17221 tgacattagt attggcattt atccaatctg tcggtatcac tgctggattc aatcaatacg
    17281 ctcaattagg tttcgtgaat aatcctaacg tagcaactta cgtaacgatc ggtttgattc
    17341 taacagccgg tacgatgttt gttacttggc taggagaaca gatcacagaa aaaggtatcg
    17401 gaaatggcgt atcaatgatc atttttgcag gtatcatttc tagattgcct gaaagtatca
    17461 gagaaattta tgaagattac tttataaata ttgatccttc agacatatgg aaatctgcta
    17521 tttttgtggc cattttacta gtagcggtct tgttgatcgt gacattcgta acatttttcc
    17581 aacaagctga acgcaagatc ccgatccaat atacgaaacg cgtagctggc gcgcctacaa
    17641 gcagctatct gccgttgaaa gtaaatgcag ctggagttat tccagttatc tttgctagtt
    17701 cgtttattgc tacgccaaat gctgttttac aagcattgag cggtagattc ggttctgaaa
    17761 actggtacaa agtgatgatg gagatcttta actataatac agcacctggt gctacgattt
    17821 atacgattct gatcgttgcc ttcactttct tctacgcctt tgttcaagta aaccctgaga
    17881 aattagcgga aaacttgcaa aagcaaggaa gttatatacc aagcgtacgc cctggtaagg
    17941 ggactgaaga gtatgtctca agattactga tgcgtttaag tacagttggt gcagtcttcc
    18001 ttggtttagt ggcattgctt ccaatcattg ctcaaatggt ttgggatctt ccacaatcaa
    18061 tcggattagg cggtacaagc ttactgatcg ttatcggtgt agctttagaa actgcgaaac
    18121 agttagaagg cttaatgctg aaacgtaaat atgttggatt cattgagtaa gaaagcgtgt
    18181 tgaggtttcc cctcaacaca cgttctcaca catttattag gagggaaaac aatgaacctc
    18241 attttaatgg ggctgccagg cgcaggtaaa ggaacacaag ctgaaaaaat cattgatgct
    18301 tatggtattc cgcacatctc aacaggagat atgttccgcg cagcgatgca aaacgaaaca
    18361 gctcttggcc tggaagcaaa gtcttatatg gataaaggtg cattagttcc tgatgaagta
    18421 acaaatggaa tcgtgaaaga gcgactagct gaaccagata cagagaaagg cttcttatta
    18481 gatggctttc cacgtacgct agatcaagca aaagctctgg acgcaatgct aaaagatttg
    18541 aataaaaaaa ttgatgctgt catcgatatc catgttggtg aagaaatctt ggtcgaacgt
    18601 ctagccggcc gatttatctg cagcaattgt ggagcaactt accataaaat tttcaaccct
    18661 acaaaagttg aagacacatg tgatcgttgc ggtgggcatg aattctatca aagagaagat
    18721 gataaacctg agacggttaa aaatcgtctg gctatcaaca tcaaaaatag tgaaccaatc
    18781 ttggcttatt ataaagaaca aggtttgcta aacactattg atggtgctcg tgaaatcgat
    18841 gctgtatttg cagatgtaca aaaaatcatt gaaaaatagc acgattgccc gtagccgact
    18901 tgcattatgc agttactctt gtcaagttca ataaattatg atagaatatg tcagtccgac
    18961 ttctagagaa tcctctagat gatccatttt gagaattttg aggtgggaac tgcagtttcc
    19021 gccattttat cgtgtgaaaa tgcgaaacaa gtacaaggag gtactgtgcg tggcaaaaga
    19081 agatatgatt gaagtcgaag gtacagtcgt cgaaactttg ccgaatgcaa tgtttaaagt
    19141 tgaactagaa aacggacacc aagttcttgc tactgtttca ggtaaaattc gtatgcatta
    19201 catccgtatc ttacctggtg acaaagtaac ggttgaattg tctccatacg atcttaaccg
    19261 tggccgtatt acttatcgct ttaaataatt gtactccgta aaactacagg aggtattatc
    19321 atgaaagtaa gaccatcagt aaaaccaatg tgcgaacatt gtaaagtaat tcgtcgtaaa
    19381 ggacgcgtta tggtgatttg cccagcaaat ccaaaacata aacaacgtca aggataattg
    19441 gaggtgctat aaatatggct cgtattgcag gagtagatat tcctcgtgat aaacgtgtag
    19501 tagtttcact tacttatatc tatggtattg gtaacactac tgctaaaaag atcttagctg
    19561 atgctggtgt atctgaagat gttcgcgttc gtgaattaac gaatgaacaa acagatgcta
    19621 tccgtgcaga agtagataaa ttaaaagttg aaggggatct tcgtcgtgaa gtgaacttga
    19681 acatcaaacg tttgatggaa atcggttctt accgtggaat ccgtcatcgc cgtggattgc
    19741 ctgttcgtgg acaaaacacg aaaaacaatg cacgtactcg taaaggccca gctcgcgcta
    19801 tcgctggcaa gaaaaaataa ttcttaagtg aaggaggtta aaacttcatg gcagcaaaaa
    19861 aagtgaatcg taaacgccgt gtgaagaaga atatagaagc aggtattgca catatccatt
    19921 ctacattcaa taacactatc atcatgatca ctgatactca cggaaatgca ttagcgtggt
    19981 catcagctgg ttcattaggt ttcaaaggaa gcaaaaaatc aactcctttt gccgctcaaa
    20041 tggcagcaga aactgctaca aaagcagcaa tggaacacgg attaaagact gttgaagtaa
    20101 cagttaaagg acctggttct ggacgtgaag cagcaattcg ttcattacaa gctacaggtt
    20161 tagaagtgac tgcaattcgt gacgtgactc cagttcctca taatggtgcc cgccctccaa
    20221 aacgccgtcg tgtttaatga gtgccgctca ttttgagttt tatcagtaac gtcattgaac
    20281 aagacacttt tcgttttgaa aggggtaaag ataagaatga ttgagttcga aaaaccaaga
    20341 atcgcaaaaa ttgatgaaga aaaagattat ggcaagttca tcgttgaacc tcttgaaaga
    20401 gggtatggga ctactttagg gaattcccta cgtcgtattt tattatcttc tttgccaggt
    20461 gctgccatca ctaatattca aatcgatggt gtactgcatg aattctctac catcaaaggt
    20521 gttagagaag acgtcactca aatcatcttg aacattaaag gcttagcgct gaaaatgtat
    20581 ggccaagaag aaaaaaccct tgaaatcgat attaccggac ctgctacagt aactgctggc
    20641 gatattatcg ttgatagtga tgtagaaatt cttaacaaag atatgtacat ctgtagtgtc
    20701 tctgaaggag ctacgttcca tgctcgctta acagtgaaac ctggacgtgg ttatgttcaa
    20761 gcagatgaaa ataaaaaaga agatatgcca attggcgttc ttccagtcga ttcaatctac
    20821 acacctgttc gtcgtgtgaa ctatcaagtt gagaacacac gtgttggaca ccgtgaagat
    20881 tttgataaat tgacgatgga gatttggaca gatggttcaa ttgaaccgtt ggaagcaatg
    20941 agtttgtctg cgaaaatcat gactgaacat ttggatattt ttgtgaactt aactgatgaa
    21001 gcaaaaaatg ctgaaatcat ggtcgaaaaa gaagaaacac aaaaagaaaa aatgttggaa
    21061 atgacgatcg aagagttaga cttgtctgtt cgctcttaca attgtttgaa acgtgcagga
    21121 atcaatactg tacaagaact tacaaataaa tctgagcctg aaatgatcaa agtccgtaac
    21181 ttaggacgta aatcattaga agaagttaaa gcaaaattgc acgacttagg tttaggttta
    21241 cgtaaagaag attaaaacct tttacgaagg agggaaacca acgtgagtta tcgtaaacta
    21301 ggacgcacat ctagccaacg taaagcgatg ttgcgtgatt taacaactga tttattaatc
    21361 aacgaacgta ttgtgactac tgaagctcgt gcgaaagaag ttcgctcaac tgcagaaaaa
    21421 atgatcactt taggtaaacg cggagatttg catgcacgtc gtcaagctgc ggctttcgta
    21481 cgtaatgaag ttgccagcgt gcgtgaagaa aatgaggaca tcgtcattga atcagcttta
    21541 caaaaactgt tcaacgatat tgcacctcgt tacgcagaac gtcaaggcgg atacacacgc
    21601 attttgaaga cagaaccaag acgcggtgat ggtgcaccaa tggttgtctt agaacttgtc
    21661 taaaatcaca ctaataacat cactttatag atgattcttt tagagtgtta tgatgttgga
    21721 agatattttt ccgagtctag ctcagcgctg ctcctcaagc gaatatcgct tggggagtaa
    21781 gcactcatca taaagtgttt ttttatacct tcaattacct gtcatgacag atatgtttga
    21841 aggcataaaa aaacatttta agcgagaaat aattgaaaat tttgtctttt tttgatagtg
    21901 ttagtaggaa ctttaggatg aagaaggagt aatcatggag ccaattattg aattagaaaa
    21961 gataaattat aaataccagc cagatgatct tcgccccgca ttgaaagatg tctcctttac
    22021 aattgataaa ggtgagtgga tcgctattat tggacacaat ggttcaggaa aatcgacact
    22081 tgccaaaacg atcaatggat tgcttctgcc agaatcaggg atcgtgaaag tgggaaatca
    22141 aatattggat gaagaaaata tttggacgat ccgacagatg gttggaatgg tttttcaaaa
    22201 tccagacaat cagtttgttg gttcgacagt agaagatgac gttgcttttg gtcttgaaaa
    22261 tcaagggatt cccagagaag aaatgctagt gcgtgtgaaa gatgcacttg agaaagttag
    22321 aatggctgag tttgcttcac gcgagcctgc tcgtttatca ggagggcaaa aacaacgtgt
    22381 tgccattgcc ggcgtggttg ccttacgacc tgatatcatt attttagatg aagcaaccag
    22441 tatgctagat ccagaaggtc gtgaagaagt gatctctacg atcaagaaga tcaaagaaga
    22501 aagtcaattg accgttatat ctatcactca tgatattgat gaagcagcta atgccaatcg
    22561 gatactagtg atgagacaag gcgaacttgt ccgtgaaggt acaccaaaag aaattttttc
    22621 tgctggtcct gaactgatcg acttaggtct agatctacca tttcctgaaa aactgaagag
    22681 cgcactgaaa gaacgtgggg ttgatgtgcc cagtgaatat atgacagaag aaaggatggt
    22741 ggattggtta tggacatccg ttttgaacaa gtagacttca cttatcagcc gaatacacca
    22801 tttgaacaaa gagccttatt tgacatcaat atgacgatca aagaaaacag ttatactgca
    22861 ttagtagggc ataccggaag cgggaaatca accttacttc agcatttgaa tgcgcttgtt
    22921 aagccaacaa gcggtacagt ccatattgga gaacgagata ttcagccgga tacggataat
    22981 aagaatttaa agcccatccg aaaaaaagtt ggcatcgtct ttcagtttcc agaagcacag
    23041 ctattcgaag aaacggtagc aaaagacatt gctttcggtc ctaaaaactt tggtgtcagc
    23101 gaagaagaag cactagtcct agcaaaagaa acattagaac aagttgggct ggatgaaagc
    23161 tatttggaac gttcgccatt tgaactttca ggagggcaaa tgcgtagagt agcaatcgct
    23221 ggtgtgcttg ccatgaggcc ggaagtactt gtattggatg aaccaacggc aggacttgat
    23281 ccccagggta gaaaagaaat gatggagatg ttttggcgtc ttcataagga acagcagatc
    23341 actattgtat tagttacgca tttaatggat gatgtagcca attttgcaga ttatgtctat
    23401 gtgttggaaa agggacgaat cgttaatagc ggggagccgc aagaggtctt tcaaaacatt
    23461 gaatggctaa aagaaaaaca actaggcgta cctactgcca ccgagtttgc agaagaatta
    23521 atggctaaag ggatgaactt tgctaccttg cctttgacag ctgaagaatt agcagacgct
    23581 atcgtccatt atgctggagg aaatgcccat gatgaataaa ttgatatttg gtcgttatat
    23641 gcctggagat tccttgatcc atcgattgga tccccgagct aaattattag ccagttttta
    23701 ttttatcgga atcatttttt tagcaaataa ttgggaaacg taccttttgt tggcattttt
    23761 cacattactt tctgtcttct tgtcaaaagt agatttgaaa ttttttatcc gaggcattcg
    23821 cccattgatc tggctaatcc tcttcactgt agctttgcag gtcttgttta caagtggcgg
    23881 agaaacttat tggagttggg gtgttttcca tatcactgaa tttggtgtga tgaacggcct
    23941 ctttattttc tgtcgattcg tgttgatcat ttttatgtcg actctactca cgcttactac
    24001 accgcctttg gaattatcgg atgcgattga gtacttgctt cgtccattga aagccgtacg
    24061 gttcccagtc cacgaaattt cattgatgct gtcgattgct cttcgttttg tgcctacatt
    24121 gatggacgaa acagaaaaga tcatgaacgc tcagcgcgct cgcggtgttg attttggtga
    24181 aggaaaccta gttcagaaaa tgaaagcagt cattcctttg ctgattcctt tatttgtcag
    24241 cagcttcaac cgtgcggaag atcttgcgac tgctatggaa gcaagaggct acaaaggtgg
    24301 ggaaggaaga acgaaatatc gtgtattgca ttggcataat agagacacga tggttatcat
    24361 tgcttttgta ttattaactg tgctactgat ctttttgaga ggataaacgt tcagtgggcc
    24421 gctatctatt cttttcttgc tgatctgttt gcaagaaagg atgcgagcag tgtatgacaa
    24481 gaaatattag ggtctgtggc agactaaggt cacaggcctc tttcttttat ctgaaaagaa
    24541 agaacgaaaa aattttataa aaaaatcatt attccagata accttttagg aacaaaggag
    24601 agaaaaacat ggtacgttac aaagcaatca ttgcatacga cggaacaaat tttaatggat
    24661 tccaaaaaca gccaaatggg cgtactgttc aagaagaagt agaaaaaaca ttacaaaaaa
    24721 tggcaaatgg aaaagaaatc acggtctttg gttcgggaag gacagatgcc ggagtacatg
    24781 cgattgggca agtaatccat tttgattatc cagaggagcg tccgttagaa cgaatgcgtt
    24841 tcgcgctaga tacccagtca ccagaggata ttgctgtaag acaagtagaa attgtttcag
    24901 aagacttcca cgcaagatat ttggtcaaag aaaagacgta tcaatttcga gtggatatag
    24961 ggaaaccacg cagtcctttt cgacgccatt atgcaagtta ttttccttac cctcttgatt
    25021 tggaaaaaat tcagcgggcg cttcctgatt tattagggac tcacgatttc acctcttttt
    25081 gtgcatcagg aagctcgata gaggataaag tacgtacgat ctacgaggct aagatggagg
    25141 taaatgaaac aaaagacgaa ttgttgttta catttagggg aaatggcttc ttgtataaga
    25201 tgatacggat cttagtagga acgcttttga aaattggcaa tggccgattg cctgaagata
    25261 gtatcccaga tattattgcg aaaaaagatc gtaatgcagc aggacctaca gcacatcctg
    25321 aaggacttta tttgtatgaa gtgaaatatg aataagaggt tgtgacagaa gtggtcagct
    25381 tcaagaaata agaaggaatt tacgaaaatt acttctcaaa attttgcaaa atttcggctt
    25441 a
//
LOCUS       DADGHT010000035        25278 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.035, whole genome shotgun sequence.
ACCESSION   DADGHT010000035 DADGHT010000000
VERSION     DADGHT010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.035"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(14..616)
                     /locus_tag="JX887_001289"
     CDS             complement(14..616)
                     /locus_tag="JX887_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAX1257291.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            722..1191
                     /locus_tag="JX887_001290"
                     /pseudo
     CDS             722..1191
                     /locus_tag="JX887_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            1297..1881
                     /locus_tag="JX887_001291"
     CDS             1297..1881
                     /locus_tag="JX887_001291"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAX1257292.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            1884..2957
                     /gene="prfA"
                     /locus_tag="JX887_001292"
     CDS             1884..2957
                     /gene="prfA"
                     /locus_tag="JX887_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAX1257293.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            2950..3789
                     /gene="prmC"
                     /locus_tag="JX887_001293"
     CDS             2950..3789
                     /gene="prmC"
                     /locus_tag="JX887_001293"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAX1257294.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            3782..3961
                     /locus_tag="JX887_001294"
     CDS             3782..3961
                     /locus_tag="JX887_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257295.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            3983..5008
                     /locus_tag="JX887_001295"
     CDS             3983..5008
                     /locus_tag="JX887_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAX1257296.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            5199..6443
                     /locus_tag="JX887_001296"
     CDS             5199..6443
                     /locus_tag="JX887_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAX1257297.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            6596..7543
                     /locus_tag="JX887_001297"
     CDS             6596..7543
                     /locus_tag="JX887_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1257298.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            7677..8306
                     /gene="upp"
                     /locus_tag="JX887_001298"
     CDS             7677..8306
                     /gene="upp"
                     /locus_tag="JX887_001298"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAX1257299.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(8445..8687)
                     /locus_tag="JX887_001299"
     CDS             complement(8445..8687)
                     /locus_tag="JX887_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257300.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            8808..8880
                     /locus_tag="JX887_001300"
     tRNA            8808..8880
                     /locus_tag="JX887_001300"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8841..8843,aa:Thr,seq:cgt)
     gene            complement(8999..9637)
                     /locus_tag="JX887_001301"
     CDS             complement(8999..9637)
                     /locus_tag="JX887_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAX1257301.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(9760..10392)
                     /locus_tag="JX887_001302"
     CDS             complement(9760..10392)
                     /locus_tag="JX887_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAX1257302.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            10743..11042
                     /locus_tag="JX887_001303"
     CDS             10743..11042
                     /locus_tag="JX887_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAX1257303.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            11537..13702
                     /gene="acm"
                     /locus_tag="JX887_001304"
     CDS             11537..13702
                     /gene="acm"
                     /locus_tag="JX887_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAX1257304.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(13974..14459)
                     /locus_tag="JX887_001305"
     CDS             complement(13974..14459)
                     /locus_tag="JX887_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAX1257305.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            14939..15580
                     /locus_tag="JX887_001306"
     CDS             14939..15580
                     /locus_tag="JX887_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAX1257306.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            15599..16234
                     /locus_tag="JX887_001307"
     CDS             15599..16234
                     /locus_tag="JX887_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAX1257307.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            16252..17067
                     /locus_tag="JX887_001308"
     CDS             16252..17067
                     /locus_tag="JX887_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1257308.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            17386..18822
                     /locus_tag="JX887_001309"
     CDS             17386..18822
                     /locus_tag="JX887_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1257309.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            19011..21458
                     /locus_tag="JX887_001310"
     CDS             19011..21458
                     /locus_tag="JX887_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAX1257310.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            21688..22755
                     /gene="rlmN"
                     /locus_tag="JX887_001311"
     CDS             21688..22755
                     /gene="rlmN"
                     /locus_tag="JX887_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAX1257311.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(22948..24051)
                     /locus_tag="JX887_001312"
     CDS             complement(22948..24051)
                     /locus_tag="JX887_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAX1257312.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            24603..25151
                     /gene="aac(6')"
                     /locus_tag="JX887_001313"
     CDS             24603..25151
                     /gene="aac(6')"
                     /locus_tag="JX887_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAX1257313.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         8708 a         4176 c         5259 g         7135 t
ORIGIN      
        1 ttgcaatctc attttaagct ttttggctga tggataagaa aagcgaagcg tttttgttca
       61 taaatagctt ttccccacga tggaaggtat gactagtagc agagacaaag cccgtttttt
      121 ccaatcgatt attcaattct tcttggctaa agccattatg gactttcgga tgactaattt
      181 gttcattctt gtcaaagtct acgatgatca attgaccgcc aggagctaaa atttcataaa
      241 gttttgtaag aatattctcc gtatcaggaa tgtgtaaaag tacaagtgat agaaggatga
      301 gattagcttg gacagcagga aattcgacag aagcatcagc gtggatcgtt cggacatttt
      361 tcagatctgc tgcttggatc ttttcttctg ccattttcag catagtttct gaagcatcgg
      421 caatgatcag ttctttgaat ctttccgcaa gcggtaaact aacaagccca gttccgcctc
      481 cgtaatccag caggactttt tggtggctgt cgcgcggtag ataagtagtt agttcttcgc
      541 gaataatctt ggctaatgct tgacggtcag gggaatcata atggttagcg atggaatcaa
      601 aaatattttt tgtcatcaaa tagctcctta cgtaaaactt tgaaatttta acttattata
      661 gcacgtgaaa agaaagaaag catgctatac tcaattcaaa aagggagaat ctagaaagaa
      721 tatgccgata tcgtttgtaa aagatagaga ggaaaaagga aagtgtgtcc gagaaatatt
      781 actagacttg cctgagtggt ttgggcttcc tgaatcaacg gaaaaatata tcgaggaatc
      841 aagtaaacta cctttatggt gtgaaaaaag aaaagaagaa tatttaggct ttatcactct
      901 ttcacagaca agtgaagata ctgccgaaat ctattctatt gtatgggaat aaaaaaagac
      961 tatcatcacc aaggattagg aacaaaactt tttaaagaag cagaaggtta cgcagcaaaa
     1021 cattacaaat atttgcaagt gaagactgta gacgaggggc actactctat atatgatcaa
     1081 actatttgtt tctacgaatc attaggattt tcaaggttgg aagtttttcc aaatttatgg
     1141 gatgaatgga acccatgttt agttcttgtc aaaaaattgg aacaaaagtg agcaatagat
     1201 ttaatactaa tctgtgcttg atgaaaattc tcactgtaaa aaatgctgaa aatcaagtat
     1261 aataccatag gaacaaactg gaaggtgaaa aagagcatgg cacaactatt ttttaagtat
     1321 ggcgcaatga atagcggcaa gacgatcgag atcctaaaag tcgcacataa ttatgaagaa
     1381 caaaataagc cagttgtctt aatgacaagc ggtattgata caagagatgg tttaggcgtt
     1441 gtttcaagcc gaatcggact gaaacgtaat gcgatgccga tatttgaaga aacagacgta
     1501 tttgacgtaa ttcagaaaat ggaaagcaaa ccctattgtg tgctgatcga tgaagcgcaa
     1561 ttcttaaaaa agaaacatgt cattgctttt acgagaattg tggacgaatt ggatattccg
     1621 gttatggcat ttggtttgaa aaatgatttt cgaaacgagt tatttgaagg atcaaaatat
     1681 ttattgcttt atgcagacaa aatcgaagaa atgaaaacaa tctgttggtt ctgccacaaa
     1741 aaagcaatca tgaatttaca ttatattgat ggaaaccctg tttatgaagg cgatcaagtg
     1801 caaattggcg gaaatgaagc ttattacccc gtttgtcgaa aacattactt tcacccatca
     1861 atgattacag aaggagaata agcatgtacg atcaattaca agcaattgaa gaccgttatg
     1921 aagagcttgg agaactttta agtgacccag aagtgatttc tgatacaaag cgttttatgc
     1981 agctttcaaa agaagaagca aacacgcgcg aaacagtcga agtttatcgt cgttataaag
     2041 aagtagtaca aggaatcacc gatacagaag aactgcttgg tgaaaaactg gatgatgaaa
     2101 tggctgaact agcaaaagaa gaattatctg aattaaaaaa agaaaaagaa gtcttagaag
     2161 aaaaaatcaa gatcttgctt ttaccaaaag atccaaatga cgataaaaat atcatcatgg
     2221 aaatccgtgg agcagcaggc ggagacgaag cagcattatt cgctggcgat cttttcaata
     2281 tgtaccaaaa gtatgctgaa gcacaaggct ggaaaacaga agtgatggaa gctaacgtta
     2341 ccggaatcgg tggatataaa gaagtgatca tgatgatcac cggagacaac gtatattcga
     2401 aattaaaata tgaaagtggt gcgcaccgcg tccagcgtgt tccttcaact gaatcgcaag
     2461 ggcgtatcca tacttccacc gcaacagttg tcgtgatgcc agaagctgaa gaagtagaga
     2521 tcgatattga agacaaagat atccgtacag atatctatca tgcttcaggt gctggcggac
     2581 agcacgtcaa taaaacagca tctgctgtac gtttgactca cttaccaaca gggatcgttg
     2641 ttgctatgca agatgaacgt tctcaaatca agaaccgtga aaaagcaatg aaaatcttgc
     2701 gtgctcgtgt gtacgataag atccagcaag aagcacaaag cgagtatgat gccaatcgaa
     2761 aatcagcagt cggaactggg gatcgttcag aacggatccg gacgtataat ttcccgcaaa
     2821 atcgtgtgac tgatcatcgt atcggattaa ctatccaaaa attagatcag attttagcag
     2881 ggaaattaga tgagatcgtt gatgcattga tcatgtatga tcaaacatca aaactggaag
     2941 ctatgcaaaa tgggtaaaat gacctatcga gaagtcctgt cacgggcttc ttctttttta
     3001 gaggatcatg ggaaagaagc atatagtatc caatttttat ttttggaacg aaaacaatgg
     3061 aaaaaacttg attggctcct tcatatgaac gaagagattt cagaagaaga acagcggttg
     3121 atcgaaaccg atctgcgact tctgcttgca gatcatccac ctcagtattt gctaggatat
     3181 gcagattttt atgatcatcg gttaaaggta actgaagcaa cactgatccc tcgaccagaa
     3241 acagaggagt tagtcgaatg gtgtttagac gagacgcctg gtgtaccgtt agaagtgata
     3301 gatattggga cagggactgg agcaattgct attagtttga aagcagcaag aaaaaattgg
     3361 catatatctg ctgtggatct ttcagaagaa gcattagaag tagcgaaaga aaatgctcag
     3421 aaagaaggaa cgaaaatcag tttttatcat ggagatacat taggaccagt aatggatcag
     3481 caatttgatg tgattatttc taatccgccg tacatcagtc ggaatgaatg ggaactgatg
     3541 gatgaaagtg tccggtcatt cgaacctaaa atggcccttt ttgctgagaa cgatggatta
     3601 gctatttatg aaaaaatagc agttgaagca ccaagcgtac taaaatcaaa tggaaagatt
     3661 tttttagaaa tcggatttcg ccaaggtgaa gcagtaaaaa aaatatttca gcaagcattt
     3721 ccagataaaa aagtggcgat aaaaaaggat ctttttggca atgaacgaat gatccaagtt
     3781 tatggttgaa gttgtggatg aaaaattttt tatttgtttt tttattataa aaaaacactt
     3841 atttgacaag gatgtaaacg actttttggt ttatcaacaa gtttatccac tattgacaaa
     3901 tagattatcc acaaacagtg gaaaacttga ggataaactc agacaaaata agaatgtatg
     3961 aaaaaggggt tgtggataaa ctgtggaaac gaaacgatat gatgaaacag aattgcaaga
     4021 ggcagccgaa gcactgaaag aaggagaact tgttgctttt cctaccgaaa cagtatacgg
     4081 attgggcgcc aacgctcttt taccaaacgc tgtcaagaaa gtgttttctg taaaagggag
     4141 accgcaagat aatccattaa tcgtccatgt cgcctctttt gaacaagtaa aagagtatgt
     4201 ggacaacttt catccggcag cagagaagat tgtgaagaac ttctggcctg gaccattaac
     4261 tttgatattt aagatcaaaa aagacacttt gccctcagtt gtgacgggag gattatccac
     4321 agctgcattt cgtataccgg ataacaaaaa aacactagaa gtaatcgaac tttccggtgt
     4381 tccgcttgtc ggtccaagtg caaatacgtc gggaaaacca agtccaacga ctgcagatca
     4441 tgtatatcat gatctacaag gaaaaattac cgggattatt gatgatggag ctacgcgaat
     4501 tggtgtagaa tccactgttc ttgatttaag tgatccaaca gccatgccta tgattttacg
     4561 accaggtgca gtaacgaaag aacaaatcga agcagtcatc gaatctcctg ttgctattga
     4621 tcagcatctt gtaaaagaaa atgaaacacc aaaagcccct gggatgaaat acaaacacta
     4681 ctcacccgat acacgtgttc tgatggtcag agatggcgat tggtcaactg cagttcaatg
     4741 ggcaaaaaat aagaagatcc gtgcaggtgt catagcaagc cccgaaattg cggatcaagt
     4801 gcggacagat actgcagctg tttatatgta taacgacaac tcagtagaag cggcggctaa
     4861 aggattgttt gcaggtctaa gaggattaga tgaaccaaca cttggattag atttgatttt
     4921 tgtacaagtg tatccagaaa ctggattggg gaatgcttac atgaatcgct tgaaaaaagc
     4981 agcaggacaa aattattttg aaaaatgatc aattggttat tgtcgcattc ttttagtatg
     5041 atacaatgct atcaagtaaa tcttctatca gtgaacgaaa aactaagcgt aactaatcgt
     5101 aatagaagag atacgaatat ttggcaattt gtttttgatg ggaaaaataa aattgtagga
     5161 aaataaaatt gtaggaaaat aaaaaggagc tgttgtttgt ggtagattac aaaacgtttg
     5221 accctgatct ttgggctgcg atcgccaaag aagaagaaag acaagaacat aatttggagc
     5281 tgattgcctc tgaaaacttt gtctccgaag cagtgatggc tgcacaagga agtatcttga
     5341 caaataaata cgcagaaggt tatccagggc atcgctatta tggtgggtgt gaatttgtcg
     5401 atatcgttga aaatttagcg attgaccgtg caaaagaatt attcggagcg aaatttgcga
     5461 acgtccagcc tcactccggc tctcaagcca acacggctgc ttatctcgct ttggtagaac
     5521 caggggacac gatcttagga atggatcttt ccgcaggcgg acatctaaca catggatcac
     5581 cagtcaactt cagtggcaaa acctatcact ttgttgctta cggtgttgat ccgacaacag
     5641 aagttattga ttataatgtg gtacgtattt tagctagaaa acatcaacca aaattgatcg
     5701 tagcaggtgc cagtgcttac ggacgaacga tcgactttgc gaaattcaga gaaatcgcag
     5761 atgaagtagg cgcaaaactg atggtagata tggcacatat cgcaggatta gtagcagcag
     5821 gacttcatcc taatccagtt ccttatgcag atatcacaac gactaccact cataaaacat
     5881 tgcgtggccc tcgaggcggc atgattttga caaacgatga agcattagca aaaaaaataa
     5941 atagtgcggt atttcctggt attcaaggcg gccctctaga gcatgtgatt gcgggtaaag
     6001 cagtagcatt caaagaagca ttagatcctg catttaaaga atatagtgaa caaatcatcg
     6061 ccaatgcaaa agcaatggtc aaagttttca atcaagcaat tggaaccaga gtcatttcag
     6121 gggcgacaga taatcatctg atgttgatcg atgttcgcga gttaggtata aatggaaaag
     6181 aagcagagag cattttggac agtgtgaata tcactgtaaa taaaaactcg attccttttg
     6241 aaacactaag tccattcaaa acaagcggta ttcgaatcgg cacgccagca atcactactc
     6301 gcgggttcaa agaagaagat gctgtaaaag tggctgaact agttgtcaaa gcattacaag
     6361 caaaagatga taacgctcaa ctagacgaag tcaaaacagg tgtacgcgaa ttaactgaaa
     6421 aatttccgtt gcataaaaaa taaaaattta aattccatta gtaaacagaa aagttcaatg
     6481 ttgggctttt ctgtttattt tttgggaaaa cggattcttt gacaatatcg gtgatgctct
     6541 ctagtatatg aggtgtaatt ttagtcttca cactaaatct cagggaggaa aagtcatgac
     6601 tgatcgtatc tcgttagaaa aggaagcagt agcattcagt gatgcaaatg cgcctcatcc
     6661 gcgtatctat gaactagcac cggaagaagg aagagtttta ctagaagaag tacaagaatc
     6721 acctgtgaac aaatattccg tcgatattga agacttgatg gtggatactg gcgaatgggg
     6781 aaaactcaat attcgtctcg tacgaccaga agggaatatg gataaattac cagttatttt
     6841 ttatattcat ggagcaggct gggtttttgg cagtgctcaa acccatgata aattgatcag
     6901 agaacttgcg gttcgtacga attccgtcgt tgtctttcca gaatatagtc gatcaccaga
     6961 agcaaaatat ccaacagcaa ttgaacaaaa ttatgctgtg ttgcaacagc tgaataaatt
     7021 agccaagtca aaaaatctgg atctcgagaa tctaatcgtt gcaggagatt cagtaggtgg
     7081 taacatggct acagtcatga cgatcttaac aaaagaacga aagggcctcc caatatccaa
     7141 gcaattgctg tattatccag tcacaaacgc tgattttgat acagattcct atcatgaatt
     7201 cggagaaaac tattttttga caagagaagg aatgatgtgg ttttgggacc aatatacgac
     7261 gaatgaagaa gagcgtgctg aaatcacagc ttcgcctttg agagcaaata taaatgaact
     7321 aaatgatctt ccttcagcaa tgattttaac gggagaagcg gatgtattaa gagatgaagg
     7381 tgaggcttat gcgcgcaaac ttcgtgatgc aggggttcct gttacacaag tacgcttcca
     7441 aggaatcatc catgattttg tcatggtaaa tgctatggat cagacaaagg caacgcgtgc
     7501 agcaatggca ttatctactt cttggatcaa gaaaaaagaa taagctttgc ttgtccgcag
     7561 gaaaacttct tttcaaaaac ggattttctt aggaaaaatg gcgagtttga ctagtcaatc
     7621 acttgatttt gttttacaat taaaaagaaa cgacagaaca aaggagagct taaaaaatgg
     7681 gcaaatttca agtgatcgat catccattga ttcaacacaa actaactatt attcgggaca
     7741 aaaactgcgg aacaaaggtt tttcgtgaag tagtcgatga aatcgctatg ttgatggcat
     7801 atgaagtatc acgggatatg ccattggaag acatcgtgat cgaaacaccg atcactgaaa
     7861 caacacaaaa aacgttgtct ggtaaaaaag tagcgattat tccaatcttg cgcgcaggta
     7921 ttggaatggt tgacggtatc ttggaattga ttccagctgc taaagtggga catatcggtc
     7981 tttatcgaga tgaagaaaca ttggaaccac atgaatattt cgtcaaactt ccagaagaca
     8041 ttgatgcacg tcagttgttt gtagtagatc caatgttggc aacaggcgga tcagcaatca
     8101 tggcaatcga tgcattgaaa gaacgtggcg cgtcgaacat taaatttgtt tgtttggtag
     8161 cagcacctga gggagtaaaa gctttgcaag aagcgcatcc tgatattgac atctatacag
     8221 cttctctaga tgaaaaattg aatgaacatg gttatatcgt tcctggacta ggggatgcgg
     8281 gtgaccgttt gtttggtaca aaataagtaa atacgaaaaa gggtgtgaca caacttttgt
     8341 cacatccttt tttggtcatt tttaacgttt gatgcagaac agctttttca cagctttcgt
     8401 ttgcatataa aaaaaccatc ccaaaaatgc agagatggtc aaattcaaat cttttttagt
     8461 tctttgtagt taacgattac tacaccctta ctttgcgtca tcaagttcgc attttctgca
     8521 gtttcatcaa tctcaacaac agcggaattt ttcaattgct ttgaaatcgt tccagtttgc
     8581 gacttgccgt gaattgtgaa cattacgtga gtattgatct tgaatttttc accaatttcc
     8641 gatggtacga tagttgtatc aaattttcca aaagttgcca ttttcataaa acctgccttt
     8701 cacatcaatt ataccacgtt ttatgaaaaa tatcatgaaa ttaaactaat tttccatcgg
     8761 actctttaca atcagccaaa tagagtatat aatttctttt ggataaggcc agcttagctc
     8821 agttggtaga gcaacgcact cgtaacgcgt aggtcgtagg ttcgatccct atagctggca
     8881 ttaaaagaga agacagatat atcaaggatt tttaatccat tgatacatct gtctttttgt
     8941 ttaaaggaaa taaagtatgc tttcttagca atagagcatg tattatttct ataaaaattt
     9001 aggagaataa aacgactagc aatatagctg tgaaatcaaa tatcacatga actgcccaac
     9061 ttgtaatgat cgagttgctt ttaatggcag cttggttgaa taacaatctt gccacccctt
     9121 gtatcaaaag gatgtgtgct acagtgtgta aaatatttcc attatcataa gtactgtaat
     9181 ggataaatcc aaagatgatt gctgacaaga aactagcgac aggaatgctg aacttactag
     9241 aaaaaatagc gagaaaatac actgagaaca attcttctcc aagtatcatg ataggcaaaa
     9301 taataaataa taacgggctg aaagcctcat ttattggatt gcctgttaaa ccccatttca
     9361 aaatttgttg caaaaatacc gagactgcgg cactgattac tacattgata aaaaaatatt
     9421 tggctatatt tttgacagga gcgacaggtt tcgagaacat ttttttcgta tcttttttac
     9481 caaaaacaag tgtaaatgct ataaatccag tgatagttaa agaaaaaatg ctaataatgg
     9541 atggcgcaaa tagcaaccct aacaaaccga gtacaacgac aatagtgccc aatatccctt
     9601 ttttaagttc tatttttttt cctaaaatgt tattcatgat aataactcct actattcagt
     9661 ttttgaagat agagtcagta tacatgaaga gttaaaatag gcaatgtttt tttatggata
     9721 tttgtattgc taaaaattta tcttatatat tcattttgat tatactactt ttatttgtaa
     9781 aaattttcta gcaaaaccaa gtgcttgcaa ctgattaagc gtacaatttt ttagatgttc
     9841 cgagcgtact tcaatcattt caaaggagtt gctacttaaa tcgatatttt ttaaatcagt
     9901 atcaaaaaag ctagcatttt ctaaatcatt agtagaaaac attattttag tgagggaaca
     9961 gtctacaaaa tctgcgcttg ataagacaga gtgctcaaag gtactttctt ttatgtttga
    10021 accagataaa tttacatagt ccattttaca attctcgaat aacgtgttcc caatataact
    10081 ttccatcaat ttagtacctg ttaatttaca attgacaaat ttcacgcgat gcaacatgct
    10141 ttttgtcaat atacagcctg aaaaatcaca gttttcgaat atacagtcgg taatctccat
    10201 tctttgaaaa tcattggaag caaaaaatgc atacttgaaa atagatttgt aaataattgg
    10261 atggcagatt atttggtttt cgatgacctc tttttgtgaa aggatattat acagttcaaa
    10321 atcttcgttt tcatagatat gaaaaaagga tcctttattc aagcttgctt cattaacttt
    10381 aggaaaaatc atatttaatt acctccattt tcataaagtc atattaacaa aagctaaacc
    10441 aacttacatt agcagaaaat gagataggtt ttcgcctttt tcgataacga tagtgtcgct
    10501 atctcttgaa acgttcttag aattgccctg agagacacaa attaggcgta attctaataa
    10561 aaatcttaga ataaaaattt ttactgattt aatttagaat gtttttaaaa taaaaatcgt
    10621 tgccataaca gtgtattgaa aggttttaac aatccagtaa tgatttaaaa aaatctagat
    10681 gtagcgtata ctttgtttat agaatgtagt gggaagaaat atatttttgg gaggaaatcg
    10741 tgatgtctaa aagtgaagaa atagaaaaca tggtactaaa attatatgat ctcgttttaa
    10801 atccagagat caaagaaaag gaacgtatac ttttgataga cgcaaagaca ggcttagaaa
    10861 aaggtcagta ttatcctaaa gtcataaata atttggaacg tagtttacgt ccgttagcaa
    10921 tcaggggaga attgtctaaa ccagtatcac cgttttatat ggagatatca acaataggaa
    10981 aatttgaaaa agaattaggt cgaggaatgg cttcggcacc gattactttt gggcatttat
    11041 aaaaacgagt tattcatctc aatgaattaa aaagtatagt caatctcata atgcaggcta
    11101 ggttcattta tttgaacaga gtctgtattt ttttattcta aataaagaaa cagatgtttc
    11161 tttatattgt attttatcct ttaattaaca caaaaacagc tagtataaac taataatgtt
    11221 aattaaaagt gtattttatg aaactatcgt tatttattaa tgttgcattt ttgtaagtta
    11281 aaaattggaa atatagattg aaaaaatgaa agcaataagt aaaataaaat gaatatatgc
    11341 gaaaaaataa tttacattag gaaaaacctt gtaaaaacag ttttttggca tatttatttt
    11401 ttataaatat ttgtaaaata actatcaatt ttttagttaa aagattggaa atgagtgggg
    11461 gaggaattga agaaaggatt tttgagagat gatatagtag gttttatttt tagttaaaat
    11521 aggggagata gaaaaaatga aaaagtgtag aaatattatt ttatcaatgt tatttattat
    11581 tactaatata acatcactga ttcctgttca tgtctatgcg gatgcaggca gagatatcag
    11641 cagtaatgtc acttcgttga ccgtggaccc aacgaatatt acagatggag gaaacataaa
    11701 agtaaaattc tcgtttgacg aaaaaaaaca aaatatccaa ccaggtgatt atctttggat
    11761 caattggcca agtgaaggaa atattcgcgg tgaaggattc caaaaagaaa tcccattaat
    11821 gattgaaaat aaaaatgttg gaactttaac ggtcagaaaa gattctgcgc aggttgtgtt
    11881 taatgaaaat attaaaaacc tagactcagt agaaggttgg gggcaatttg agatacaggc
    11941 cagaaacgta accgataccg gtgaagaaaa tacgggacca ttcaccgtga cgagcggtga
    12001 taaaacagct actgtaaatg tgacaaagcc agcttctggt tcttcttcta gcgtttttta
    12061 ttataaaaca ggagacatgc tacctgaaga tactaagcac attcgatggt ttttgaatat
    12121 taacaataac ggcacttatg ttgaacaacc agttaaaatc agtgatgaaa tccaaagtgg
    12181 acaaagatta gatccaagta cgtttgaaat taatcaaata cacttaggtg aacagaaggt
    12241 ttatagagga gaagagggaa tccaacaatt tttacaagat ttccccagcg ctacatttaa
    12301 tttttcagta actgataatt acattgaaat aactatacca aaaaactttg tcaatcttag
    12361 gaaaataatg gtgagttata agacgatcat agaaaaccca gaacaaataa attttgagaa
    12421 tcattcggaa gcttggttta aagaatttaa taaacctgct gttgatggag aaagtttcaa
    12481 tcatacagtt aaaaatattt cagcttctgg tggagtcaac ggtacagtta gaggcgaatt
    12541 gaagattttc aaatatatca atgacacaga gattggtatc ccaaatgtga ctttcgaatt
    12601 aagacgagca gatgaacagc ctattcaagg acagtctagt atcctgttga cttcgaatga
    12661 acagggagaa gctagtatca aaggcctgca agtaggagac tatgttgtaa aagaaaaaga
    12721 agcacccaat tggattgatt ttgatccact aagttcaaat gaactcaaat tctccataaa
    12781 cgaaaatgat acagagggag tcagtttacc tatttataac aagaaaaagg ttacgaacat
    12841 cacagcaact aaaatttgga acggtggaac cactccaaga ccgagtattt attttaaatt
    12901 attcagagca agtacaaaca attgggaacc agttcctgat gcagaaacaa aacgattaga
    12961 caatggaata acttcagtga cttgggaaga tatccaacag tatgatgata gtggaaacga
    13021 atatacgttt aaagtgcaag aagtagatca aaacggaaat gattatgtcc cttcaggtta
    13081 tcaaaaaatt gaaaacgggc tagtcgttac aaatgagaat aaagaagtca tttcagtctc
    13141 aggacaaaaa acatgggaag acaatgagaa ccaagacggc aaacgaccga cgacgatcac
    13201 agtaaatcta ttagccgacg gtcaaccgat ccaacacaaa gaagtaagtg aaaaagatga
    13261 ttggcgctat cgtttcacaa atctgccaaa atacagagac gggcaagaaa tcatctatac
    13321 tgtaacggaa gacaacgtgc ccgaatacag tacgacgatt gacgggtata acatcaaaaa
    13381 cagttataca ccggaaaaaa caaatatatc tataccaggt agccatataa caccgtggaa
    13441 aaattttcca gagaagacag agagagagaa aattagaaat ctattctctc aaaaattgca
    13501 aatatttgct catacaggag aatccagcga acaaagaagc aattatatta gtaagagagc
    13561 tgtacctaaa cagataacaa ataaatcaaa aagcattctt cctaaaacaa gtagtaaaaa
    13621 atctagtttt gctgtaatca ttggtttatt gatagtaact atctgtgctg ggatattctt
    13681 acaaaaatat aaaaaagttt agttagaata taatattttt tgttaaatat gactgaaatc
    13741 aaaagaataa aattccgatt tataatcgaa aaaagaagca tttttatata tgcttctttt
    13801 ttcgtagaat caataaatat ggatttggct aactatggaa gaatactcgt attagttttc
    13861 agcgttcata ctagttgtta cattgtttga ttggccaaaa gaatttctga tatattttgt
    13921 gctaaataaa gaaaaagacg cttgaattgg gaaataagaa aactactcta tcattacaaa
    13981 ttttcataaa ctggcagatg ttctaagtaa acaagtatct tttcaaagtc ggaaaaatcc
    14041 ataatcaacg tagtggtatt gatatttgga tgaaagccta cggtatcttg acgatcaata
    14101 gcagcatcga tcacgacttg gatttttttc tctttgtcgt gcatcaatgc taatggagtc
    14161 actgtacctg ctggaacgcc taggaggtca ggaagctgtt cttcagaaac aaaagataag
    14221 cgcttttctt ttaattgttc agctagttgt tttaaatcgg cgtgcttttc atcaggcaag
    14281 atgacaagat agatttgttt tccttttctt gatttcaata atagattttt tacttgcgga
    14341 ccaggtaggg aaaaagggac atttttgact gacgtaatcg caggatgatc gactttttga
    14401 aaagagatac ccagtttttt tagtagttca taagcttctt gttcggttgc acgactcatc
    14461 gcgcatcacc ctcctttttt tattagtgta tcataaaaaa gagttgacaa atgaaaaata
    14521 atcatgtaaa ttacacgtaa agttaaaaca aatgacatcg aaaagaagag tagccgttag
    14581 gtgtttttag agagtctctg gttggtggaa agaggcagca gttaaccgtg aaacacatct
    14641 tggagtcgat tttctgaagc gtatagtagg aaaatccggg gagcccgtta cagctgcggt
    14701 cgttgctaga tgaccagata aggctggctt ttccgtgagg agtcggtaaa aaaaggtgga
    14761 accacgtgat taacgtcctt tgatcttcgg atcaaaggac tttttgtttt catctgaacg
    14821 gcaacgactg tgtgaggttt tttctgcaag gaaaaaataa acagaggtgg aaccacgtat
    14881 aatacgtcct cttggcattt gccaagagga tttttttatt ttaaaggagg aaaagaagat
    14941 ggagtatttg attgaagtta tgccgcaatt attagtagga gcactcacaa cattgaaatt
    15001 atttttattt accttgattg gctcattacc attagggatt gttttagcat taggattgtc
    15061 tttgcatttt aagccgctac gctacttgct tcaaacatat gtatgggtta tgcggggaac
    15121 accgctgttg ttgcaactga tttttatttt ttatgggttg ccgacgattg ggatcgtttt
    15181 tgatcgtttc gaagcagcac tcattgcctt tatcttaaac tatgcagctt attttgcaga
    15241 gatctttcgt ggagggatac aatcgattcc tcaaggtcaa tatgaagcag cgcaagtttt
    15301 gcaattaagt ccctttcaaa cggtgacgaa aatcgtcatc ccacaagtga caaagattgt
    15361 tttaccttct gtagggaatg aagttatcaa cttggtcaaa gattcttcct tgatctatat
    15421 attaggttta ggtgacgtaa tgcgtgctgg gaaaatcgcg atggaacgcg acgcgacttt
    15481 actgcctttg ctaggcgtgg caatcatcta tcttacattg actggtattc taacaatcgt
    15541 aatgaaacaa gttgaaggaa aattaaatta ttaccgctaa ctgataggag gaagaaatat
    15601 gattgaattg aagaaagtga acaaagcatt tggtgaaaaa aaaataatca aagatttgaa
    15661 tctaatcatt ccagatggga aaacattagc tatcgtaggt ccttccggtg gcggtaaaac
    15721 cacgctttta cgtatcttgg ctggcttaga aagttctgac agcggagaat tttatttaga
    15781 cggtgtaccg ttcaacccat tcgagcttaa aatgaaagaa caagttgtag gagtcgtatt
    15841 ccaagacttc cagctatttc cacatctgaa tatttttgaa aacattacct tagcaccaaa
    15901 aatggtattg aaacagacaa aagaagaata caccaaaaaa gcagaagaat tagcggcttc
    15961 attagggatt agtgatttat tgaatatcta tccttatcag ctttctggcg gacaaaaaca
    16021 gcgggtagcg attgccagag cattggctat gaatccacgg gtattggctt atgatgaacc
    16081 aacaagtgct ttagatcctg aattacgcca gcaagtcgag cgtttgatcc tatcattgaa
    16141 agaagatggg gtaacccaaa ttattgtcac ccatgattta gtatttgcag aaaatgtcgg
    16201 tgatcaatta ctaaaagttt ccccaattca ttaagaaagg agaagataga gatgaaaaaa
    16261 accagttttc tattcgcttt gatcgcaggt cttcttcttt ttgcaggctg ttcgaacaaa
    16321 aaaacttcag cagataattg ggcgactatc aacgaagaga aaaaaatcgt tataggttta
    16381 gacgatacat ttgttcctat gggatttaga gataaagacg ggaagctcac aggatttgat
    16441 attgatttag ccaaagcagt ctttgaacaa tatgggatta cggtagactt tcagcccatt
    16501 gactggtcaa tgaaggaatt tgaactgaac aatggaacga tcgatttgat atggaacggc
    16561 tattccaaaa cgccggcaag agaaaagaaa gtgcaattta caaaacctta tatggaaaac
    16621 gatcaagtgc tgatcacacc taaagaatca ggaatcacaa actttggaca aatgaataat
    16681 aagagattag gtgcgcaaaa tgggtcatct ggttatgatg tatttacgaa acaaccagaa
    16741 gtattaaaag agatagtcaa aaaccaagat gctgttttgt atgatagttt taatgaagca
    16801 ttgatcgatc tgaaaagcag acgggtcgat ggtctgctga tggataaagt atacgcagac
    16861 tattatttga aacaaagaaa cgaactagaa gacttcaaca taacaaaagg ttcttatgag
    16921 agtgaggatt ttgcagttgg tgcacgcaag tcagatagta cattagtgaa aaaaatcaat
    16981 gaagccctag atcaactaga gaaaacaggt gaattccaaa aaatatccga taaatggttt
    17041 ggcgaagatg ttacgccgag aaattaacaa ataggggact gtgacaaaag acgtgtcaca
    17101 gtcccttttt ccgaataaac agtgttctcc tgccaactcc ttgtgactcg gagctgaatg
    17161 gcaggctcac aacctcttgg taaacggtgt tcaaaagcca gtttttcggt attaagccaa
    17221 atttatgcaa aaatgtagaa agccattttc acaaaatttt tcttactact cgaaactaag
    17281 cgactttttc acaacctcct ttacataatt ttattttgtt gtggaagggg tttcgtgtta
    17341 ttctaaaaga ggaacgattg aaggttatag gaaaggaaga gatgaatgga acacaaagaa
    17401 cttacctcat ttccaaaaga ttttctgtgg ggctctgctt ctgcagcgta tcaagtagaa
    17461 ggagcttggc aagaagatgg gaaaggagaa tcagtctggg atcgatttgt acggatacct
    17521 ggaaagacat ttaaaggaac gaacggtgat ttggcagtag accactatca tcgttataaa
    17581 gaagatattg ctttaatgaa agaacaaggt ctgaaagctt accgcttctc tgtagcttgg
    17641 acacggattt ttcctaatgg acgaggagaa gtcaatcaag ctgggctcgc tttttatgag
    17701 agattgatcg acgaattgat tgaaaacgat attgaaccta tgttgacttt atatcattgg
    17761 gatcttccac aagcattgca agatgaatat aatggttggg aatcacgtca gatcattgaa
    17821 gatttcactc attatgcaga aacattattt gaggcattcc gcgggaaagt ccattactgg
    17881 attagtttga atgaacaaaa tatcttcact tcattaggtt atttgttagc agcacatccg
    17941 ccaggtgtga cagacccgaa acgaatgtat gaagttaacc atattgctaa tttagcaaat
    18001 gcatctgtca tcaataaatt tcacgagtta gaaatgcctg gaaaaatcgg accaagcttt
    18061 gcgtatacgc caaattatcc aattgacagt aatcctgaaa atgttctggc tgctgaaaat
    18121 gcagaagacc tgatggccaa ttattggatg gatgtctata tgtggggaaa atatccgatt
    18181 gctgccatga ggttcttaga agaaaaagga tgggcaccaa cgattgaagc tggcgatgca
    18241 gaattgctag aatctgctaa accagatttt cttgggatca attactatca aacggcgacg
    18301 aatgcattca atccattaaa cggagttggt gctggaaaaa tgaatacgac aggaaaaaaa
    18361 ggttcatcag aagaaactgg agttcctgga atgtataaaa aagttgagaa tccatttgtc
    18421 gaacgaacaa attgggactg ggagattgac ccagaaggat taaggatcgg actgcgtcgt
    18481 atcacaagcc gttaccgcat gccggtactg attacggaaa atggcttagg agagtatgac
    18541 aagttgacag aagataaaca aatccatgac gactatcgaa tcaattactt acaaagccac
    18601 gtcaaagcca tcaaagaagc aatttcggat ggagcagaag tcctaggcta ttgcacctgg
    18661 tcttatacag atttgcttag ctggctgaac ggttatcaaa agcgatatgg atttgtatat
    18721 gttgatcaag acgaaacaca agaaggatct ttggaacgat ataagaaaga cagttattac
    18781 tggtaccaaa aactgattga agaaaatgga gagaaccttt agttcacata cttaaaacaa
    18841 gaaggtacgg ctggatatgg ccgtgccttt tcttgataaa atcatttaga aattaagaaa
    18901 aactgtaaaa taagctgaaa aatgaaagaa agcgtcagtt ctttcaaaca aaactttagt
    18961 tcccttactt ttttttgtat aatgaaactt gatgaaatga gggataataa atggcacaaa
    19021 agaaacggcc tactaaaaaa aggaaaaaga cgaaaaaaac gaaaaagcaa aaacagcagc
    19081 aggaacaaat gctgacgatt ggtgttgggt ttgccttgat tttatttgct gtcttcggct
    19141 ttttaaaatt aggtttttta ggaatattga ttgcaaacgg ctttcggatc attgcaggaa
    19201 atacttacca aatcctctgt cttttattag ccgtattagg attttggatt gtcattaaga
    19261 atacagagtt ttcaattggt aaaaaccgac gctggtttgg cggcatactc ttttatttcg
    19321 gtatcttatt attgttacat gcccatttat ttggcaaact ccatactggg gaaccaaata
    19381 tcatggggac gacatgggat ttgttagcca gtgatataaa acaaagtcaa gtagacaata
    19441 acgttggtgg tgggatgatt ggagcaatcc tttatcattt tacttacttc ttgattgcac
    19501 agcctggaag ttatttagca gcagtgctat tactggcagg aggagcattc ctgttcagta
    19561 atctggaagg ctatcagctg ttaaatggta tccaatcaat tggagaacga gtacaggaat
    19621 tattggaagg tgatcctgcc aagcaagctc gaaagcaagc ggcaaaggaa gagagaatga
    19681 aacagcgcgc agaagcgaaa gaagcaaggc gcttagctgc aaaagaagct gcagaaaaag
    19741 aagctgcaga atatgagaag aaaaaagcgg tgagccagca aagggaaaat actgctgatg
    19801 aatggcagga accagaaaat acagagccgg agcagctaag ttttgttcca atcgacagtt
    19861 ttcaagaaaa tatccatcct gcgaatctag agaaaccagt accagataca ccaaaacaga
    19921 ccaatacagc agaaggtttt tcagatgagt tgccagagga tgacggtacc tcattagaat
    19981 ttgagattga agcagaacag gaaaatcaag actatgaatt accgacagtt gatttgcttg
    20041 attctatacc aactgtggat caaagtgatg agtataaaaa aattgaaaaa aatatcggcg
    20101 tattagaaca aactttccaa agtttcggtg tcgatgccaa ggtcgtcaaa gccagcttag
    20161 gaccatccgt cacaaaattc gaagtccagc cggctgtagg ggtaaaagta agtaaaattg
    20221 tgaacttaac agatgatatc gcgcttgctt tagcggcgaa agatgtccgg atggaagcac
    20281 cgattccagg taaatcactg attggtattg aagtaccaaa tggaaagatc agtatggttt
    20341 cctttagaga aatcatcgaa gcacaaccaa accacccaga taaattacta gaagtacctt
    20401 taggacgtga tgtttctgga cgggtacaaa cggctgatct ttcgaagatg cctcacttac
    20461 tcgtggctgg ttcgactggt agtgggaagt cagtagcaat taatgggatt atcacaagta
    20521 tattaatgcg tgctaagccc catgaagtaa aactgatgat gatcgatccg aaaatggttg
    20581 aattgaatat gtacaacggc atacctcatc tgttgacgcc ggtcgtgacg aaccctagaa
    20641 aagcagcgca agccttacaa aaagtagtac aagaaatgga agaacgatat gaaaaattcg
    20701 cggcaaccgg agtaagaaat atttctggtt acaatgaatt tgttcaacag aaaaacttgg
    20761 aaaacggaac gaaacatcca accttaccat tcatcgtagt gatcgtagat gaattagctg
    20821 atttgatgat ggtagccagc aatgaagttg aagatgcgat tattcgttta gcgcaaatgg
    20881 ctcgggcagc ggggattcat atgatcctag ctactcaacg tccaagtgtg gatgttatca
    20941 caggaatcat caaagcaaat gtaccttcca gaatggcatt tgcggtatca agcggtacag
    21001 attctcggac gatcattgat tctaatgggg cagaaaagct cttagggcga ggagatatgc
    21061 tattcttgcc aatgggtgag aataaaccga tccgtgtgca aggagcattc atttctgacc
    21121 acgaagtaga acgggtcgtt caatttgtta cagatcagca agaagctcat tatgaagaga
    21181 aaatgatgcc gacagatgaa gttgaaacga caggtgctcc agaacagcca caagatgagc
    21241 tgtttgaaga agcaaaagca cttgtcgttg aaatgcaaac ggcaagtatt tcccttctcc
    21301 aaagaagatt tcggatcggt tacaaccgag cagcacgttt agtagatgaa ctggaagctc
    21361 atggagttgt tggcccgtca gaaggaagca agcctcggaa agtattcatt gagcaggaag
    21421 aaacatcaga aacgttgccg gacgataatg acatgtaaaa cttgtgtgat gaagggttga
    21481 aaaacgaata accaataaaa agacaaggca tgatgatacc aaaagaaaaa atggtttttt
    21541 tccatctttt ctaatacggt atgatgtctt gtctttttag tttttgtgag attaaagttc
    21601 tattcgattt atttgtgaag tattgcatta aggaaatgaa tcatgtatag tatgtagcga
    21661 aactttgaga aaaagaggga aaatactttg gaaaaacagt ccatttatgg cttgacgaat
    21721 gaagaattaa tcaattggtt tatagaaaac ggcgagaaaa aattccgagc tgcccaagtt
    21781 tgggaatggt tgtatcaaaa acgtgtaagt aatttcacag aaatgacgaa tctatcgaaa
    21841 caattgatcg aaaaattatc ggagcatttt atcatcaatc ctctaaaaca gatggtcgtc
    21901 caagaagctt cggatggtac agtaaaatat ttgtttgaac tccctgataa aaacatgatt
    21961 gagactgtac tgatgagaca agaatatggc ttgtcagttt gtgtgacgac acaagtagga
    22021 tgtaatatcg gctgtacgtt ttgtgcaagc gggctgctca aaaagaaccg tgatctgact
    22081 gctggagaaa ttgttgcaca gatcatgatg gtccaacatt attttgatga gcgcaatctt
    22141 ggcgaacgcg tttcacatgt cgttgtaatg gggatcggtg agccatttga taattacgac
    22201 aatgtaatgg actttttgca tatcatcaat gatgccaaag gattggcaat tggtgctcgg
    22261 cacattacag tttccactag tggattagca cacaaaatca aggaattcgc taataacggc
    22321 ttgcaagtca atctggctat ttccttgcac gcgccgaata atgaggtgcg aacatcgatc
    22381 atgcggatca accgaagttt cccaattgag aaattgatgg aagctgtgga tgagtattta
    22441 gagaaaacaa accgtcgaat cacgtttgaa tatatcatgt tgaatcaagt aaatgataga
    22501 ccagagcatg cgcaacaatt agcagatcta ttaaaagata agaaaaaatt agcatatgtc
    22561 aacttgattc catataatcc agtcagtgaa catgatcaat attctcgcag tccaaaagct
    22621 gatgtattga gattttatga tgtattgaag aaaaacggcg taaactgtgt gatacgtaaa
    22681 gaacatggta cagatattga tgcagcttgc ggacaattgc gaagcaagca aatgaaaaaa
    22741 acagttgcca aataatcgta tcctactcgt tttttcaatt accataaaag gagcagtttt
    22801 cttaattaag gaactgttca acttaaataa gagaaaagat tctatagcga aagctataaa
    22861 gctttttttg acaagaaaaa ccctcatcaa gcaaagaaat gtcctcaatt tgatgacagc
    22921 ctgcttgatg ggggttttag caattattta actgattttc ttatatcctt gctggctttc
    22981 ttgtgtagca tgataagttt ctacgtcaag aatggcctgt ttaaattttt ctcgggtgat
    23041 ttcataaggc acatgtttaa tatcatttgt tgccatggct ttatctaaga ttgcttctaa
    23101 atcggtcgtg acattgagat tcatgtcggt taacgatact ggaagttggt tctttttcat
    23161 aaacacatag attttatcaa acaaatcgaa ctgctgatcc atcatcaata aggtcagtac
    23221 accataactg acagatgctc cgtgaaggta tccctccatt ttttctagaa cagtcgtacc
    23281 gtaatagaat gagtgtgcca tagcagaatt atagttattg ttaactaaaa cagaaaccaa
    23341 tccggtagta acaatgatat ccgaaacgac ttgttcaatt gcatatgagg gacgatcgtc
    23401 ggcactatct ttcaatgctt gcgtaccata agtcaagaga cgatcaatgc acatttttcc
    23461 gatttggatt cctaatctat ccgtgtagcc tagatcatcg ccacgagcag aaaaagtaga
    23521 ttcgacttct ttggataaag catcgccaat acctgcccat aagtatttat caggtgcttc
    23581 ggcaataatt gctgtatcaa tgaaggtgtg tacaggtggt tttgaaggaa agaagagtcc
    23641 gtccattacg ccttcttcgt tatagatgac acataccgca gtgacgggcg aacagttcga
    23701 accaatagtg ggaaaggtga agactggttt agctagtttt tcaccaatga cttttacagt
    23761 atcgcaagca cggccaccac cgactgcaaa caggacgtct gctttttgga cactttcatg
    23821 ctggatcaac tgttcaatat ttccataagt tgaattaccc ccgtaccaga gactggcgac
    23881 aacctctatt tcctgtgtca aagctacttt tattttgttt tctgcctttg aaagtgcagt
    23941 cttccctcca atcagcacta cttttgtccc atattctttg acgattccat ttgctttttc
    24001 atacgcatct gttccaatgg tataatttgg taagaaaaca ctttgactca tattcatttc
    24061 cttctttctt cgttgaaacg ggttaaaatt ttaaagagtg atcgatctga ctgcggctgt
    24121 agatggagta gaggtgaacc taagacagga taagtgatga ataaggtggc atgaacacct
    24181 tgaaatcatc aataagtatc ctaaaaacga acaagtacaa aaacattgaa aacgacaata
    24241 atgaattttt gttcctctta gtatttctac cgattccctt tgcttttttg taattatcta
    24301 aaaattctaa aaattaagat tattatatga aaacaggttt tatttgtcaa ttcataattg
    24361 gtttttttta aagcaaaaga taatctatat catgatgaac aaacagagtt ttttcctcca
    24421 attgatggct ttcctgatct ttcctatttt gaataaagtg tttctgtata attttttatt
    24481 ttataagtaa gataaataat gaaagaatag agatactgat tggtagctaa agatttttga
    24541 gcgagaacat ttcgtttttt caaaaggact gttagaataa gcaagaacaa gggggaagac
    24601 gtatgataat cagtgaattt gaccgtaata atccagtatt gaaagatcag ctttctgatt
    24661 tactgagact gacttggccg gaagaatatg gagacagctc ggcagaagaa gtagaagaaa
    24721 tgatgaatcc agaacgaatc gcggtagcag cggtagacca agatgagtta gtaggattta
    24781 ttggtgcaat ccctcaatac ggtatcacag gttgggaatt gcatccatta gttgtagaaa
    24841 gctcccgacg aaagaaccaa ataggtactc gattagtcaa ttacttagaa aaagaagtag
    24901 cttccagagg aggaatcacg atttatttag gtacggatga tttagaccat ggaacaacgt
    24961 taagtcaaac ggacctgtat gagcatacat ttgataaagt ggcttccatc cagaaccttc
    25021 gtgaacatcc gtatgaattc tatgaaaaat taggttataa aatcgtaggt gtcttaccaa
    25081 atgcaaatgg ctgggacaaa ccggatattt ggatggcaaa aacgattatt cctcgaccaa
    25141 attctcaata ataaaaagag gttgtgacag aagtaatcag cttcaagaaa taagaaggaa
    25201 tttacgaaaa ttacttcttg aatttttgtg aaattccaac ttatttccga agaagctact
    25261 tttggaacac cgtgtacc
//
LOCUS       DADGHT010000036        24495 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.036, whole genome shotgun sequence.
ACCESSION   DADGHT010000036 DADGHT010000000
VERSION     DADGHT010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.036"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(121..489)
                     /locus_tag="JX887_001314"
     CDS             complement(121..489)
                     /locus_tag="JX887_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAX1257314.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            660..1616
                     /locus_tag="JX887_001315"
     CDS             660..1616
                     /locus_tag="JX887_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAX1257315.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            1689..1805
                     /locus_tag="JX887_001316"
     CDS             1689..1805
                     /locus_tag="JX887_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAX1257316.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(1860..3542)
                     /gene="recN"
                     /locus_tag="JX887_001317"
     CDS             complement(1860..3542)
                     /gene="recN"
                     /locus_tag="JX887_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAX1257317.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(3560..4009)
                     /locus_tag="JX887_001318"
     CDS             complement(3560..4009)
                     /locus_tag="JX887_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAX1257318.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            complement(4116..4934)
                     /locus_tag="JX887_001319"
     CDS             complement(4116..4934)
                     /locus_tag="JX887_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAX1257319.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(4943..5833)
                     /locus_tag="JX887_001320"
     CDS             complement(4943..5833)
                     /locus_tag="JX887_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAX1257320.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(5835..6059)
                     /locus_tag="JX887_001321"
     CDS             complement(5835..6059)
                     /locus_tag="JX887_001321"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAX1257321.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(6064..7401)
                     /locus_tag="JX887_001322"
     CDS             complement(6064..7401)
                     /locus_tag="JX887_001322"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAX1257322.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(7402..8256)
                     /locus_tag="JX887_001323"
     CDS             complement(7402..8256)
                     /locus_tag="JX887_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAX1257323.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            complement(8353..8802)
                     /gene="nusB"
                     /locus_tag="JX887_001324"
     CDS             complement(8353..8802)
                     /gene="nusB"
                     /locus_tag="JX887_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAX1257324.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            complement(8795..9220)
                     /locus_tag="JX887_001325"
     CDS             complement(8795..9220)
                     /locus_tag="JX887_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAX1257325.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            complement(9466..10530)
                     /locus_tag="JX887_001326"
     CDS             complement(9466..10530)
                     /locus_tag="JX887_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAX1257326.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            complement(10702..10947)
                     /locus_tag="JX887_001327"
     CDS             complement(10702..10947)
                     /locus_tag="JX887_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAX1257327.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            complement(11086..11460)
                     /locus_tag="JX887_001328"
     CDS             complement(11086..11460)
                     /locus_tag="JX887_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAX1257328.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            complement(11543..12457)
                     /locus_tag="JX887_001329"
     CDS             complement(11543..12457)
                     /locus_tag="JX887_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAX1257329.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            complement(12478..13281)
                     /locus_tag="JX887_001330"
     CDS             complement(12478..13281)
                     /locus_tag="JX887_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAX1257330.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            complement(13314..14303)
                     /gene="manX"
                     /locus_tag="JX887_001331"
     CDS             complement(13314..14303)
                     /gene="manX"
                     /locus_tag="JX887_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAX1257331.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            complement(14406..14897)
                     /locus_tag="JX887_001332"
     CDS             complement(14406..14897)
                     /locus_tag="JX887_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAX1257332.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            complement(15088..17922)
                     /locus_tag="JX887_001333"
     CDS             complement(15088..17922)
                     /locus_tag="JX887_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1257333.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            complement(18329..18622)
                     /gene="rpmA"
                     /locus_tag="JX887_001334"
     CDS             complement(18329..18622)
                     /gene="rpmA"
                     /locus_tag="JX887_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAX1257334.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(18635..18979)
                     /locus_tag="JX887_001335"
     CDS             complement(18635..18979)
                     /locus_tag="JX887_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAX1257335.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            complement(19006..19314)
                     /gene="rplU"
                     /locus_tag="JX887_001336"
     CDS             complement(19006..19314)
                     /gene="rplU"
                     /locus_tag="JX887_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAX1257336.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            19596..20237
                     /locus_tag="JX887_001337"
     CDS             19596..20237
                     /locus_tag="JX887_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAX1257337.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            complement(20299..21930)
                     /locus_tag="JX887_001338"
     CDS             complement(20299..21930)
                     /locus_tag="JX887_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAX1257338.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(22053..22412)
                     /locus_tag="JX887_001339"
     CDS             complement(22053..22412)
                     /locus_tag="JX887_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAX1257339.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            complement(22571..22644)
                     /locus_tag="JX887_001340"
     tRNA            complement(22571..22644)
                     /locus_tag="JX887_001340"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22608..22610),aa:Arg,seq:tct)
     gene            complement(22953..23636)
                     /locus_tag="JX887_001341"
     CDS             complement(22953..23636)
                     /locus_tag="JX887_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAX1257340.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            complement(23764..24282)
                     /locus_tag="JX887_001342"
     CDS             complement(23764..24282)
                     /locus_tag="JX887_001342"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAX1257341.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
BASE COUNT         7175 a         5342 c         4028 g         7950 t
ORIGIN      
        1 ccactttcta ccaccttttc tgggaaatcc gggaacaact ttttttattc ataaacattt
       61 ttttaaaaat caagctgcaa aaagcctttt aaaagacttt ttacagcttt tctatttttt
      121 tcataggtaa gaaagtatgt tcacaatgat caagacagcg tacaagacga ttgtcaacag
      181 aaaaaccaaa cgccaagtca tcttgaaata acgcggataa ataatttctt cataataata
      241 tgcttggaaa acagcaatac aaattcccat tagcaaaaca gaaataaaga aaaacggtaa
      301 gatagaaatt gtccctgtat ttctagacaa tgcatgcata ccgccccaca aaaaaggaat
      361 cgccaaatca ggggctttta ttttaaaacg acgatttaac gaaaataatt ttacaagaaa
      421 ttggcaacca aacaaaacga ttaccgggta aatataccaa aacaagataa gtggtgtgaa
      481 tgtgcccatg aacgtaaact ccttttttat cgttgcttca agtatactgt atatacttta
      541 cacaactgtt tcattttatt taaatttatg cagttatatt ctatatctta caaacacatt
      601 ccatgtattc caattcccta tccgttataa taaaagaaac aggcaacagg aggaaaatca
      661 tgatcaaata ttttacatta gataatgaga aactgcgtaa taccggaaag gaaactgacc
      721 aaacgatctg gtattgtgta gaacgtccta atcaagaaga gattcatcag ctgacacatc
      781 aatttgaaat tccgtcagat tacatcactt ccatattgga cgatgcagaa aattcccgta
      841 cagaagaatt caatcaatca aagttgacaa agccagcgtt attattgtta caatatcctt
      901 ttgctaaaac aagtcctagc ggttattttc aagtggatac atacccgctc tctattattt
      961 tgacgcccaa aaagaagctt atcacaatta cgaatcatga accactgttt ttaaagaaag
     1021 tctttagcca gacctttcca aaaagtgata tttcgcctaa tctcaatatc ttctttcaat
     1081 tcatttggca ggtcacactc tcttacaaca gttatttagc tacgcttcaa tctcaatgcg
     1141 atactttgga agccaaactt caagtatcca ctgaaaacaa acaactttat caaatcatgg
     1201 atatccaaaa aagcctcgtt tatttcagag aagcgacttc tgctaattta gatgcattga
     1261 aagaactagc gcaaaataaa cttttccaag aaaatcatgc tttgaaaaat catttacgtg
     1321 atgtattggt ggaaacagag caggcaatga ctacttctcg cattcaatta aaactagtag
     1381 aacaaatgaa tcagactttt tcagcaatcg tatcgaataa tctgaataat attatgaaaa
     1441 ttttaacttc tttaacgatt attttaacta taccgacaat cgtcggcagt atctatggaa
     1501 tgaacattaa gttacctatt gctgaaaggg atgatgcctt tatatggcta gttctattaa
     1561 cattatttat ttgtatcgta actacctatt atttaaaaaa agggaagttt ttataaaaaa
     1621 gccctcttgt ggaaatggaa aaaagattgt acacttgaat caactaatta atgacgaggt
     1681 tgaaaacaat gcgtgaaaaa aaacaaacaa gtacttttgc taaagtaaca aaatttgtca
     1741 tttggacaat gctgatttta acgattggat ctgttgtatt gactgctgta atgagtgtca
     1801 tgtaaaaata aaatatagct atcagctgct gaaaaggacc tgaaccactg cgaggtggct
     1861 caggtccttt ttgcgagttt caatagttct tttgcatgtt cgagtgtgag ttttgtaatc
     1921 tcacttccag ccagcatacg tgcaatttct tcttctcttt cttttgtttt caactctgaa
     1981 acagaagttt gcgtacgtcc atcaatcact gctttcacaa tataatattg atagtcggcg
     2041 actgcagcaa cttgaggcag atgagtgatg cacaaaactt gagagtattt cgatatttga
     2101 gaaattttat ctgcgatggc ctgtgcaact cttccgctca cacctgtatc cacttcatca
     2161 aaaataatac ttgtcacacc ttgctcagaa gaaaaaatag ttttcaaagc aagcaacatc
     2221 cgagacagtt cgccaccaga agcgactttc accaaaggct tcagtggctc tcctggattg
     2281 gtcgtaatgt aaaattcgat ttggtcaaat ccatcatgat tcaattgtct attttcttct
     2341 tttaagaaac gtacctcaaa ctcagtgttt tccatataca gacttttcaa ttcatgcaga
     2401 atggattttt ccaattcttt tgcgattttt ttacgcgctt catgaagatc tgcggcttgt
     2461 tgctgaagta gaagctcttt ttgctctagt tcctctttca ttttgtccaa ttgaccttct
     2521 gaaaaatcag aagaagctag ctcttcggtg atttcgtcat agtaagccaa tattgactca
     2581 atggattcgc cgtatttacg tttcaactgt cggattaatt ctaaacgttg cgtaacttct
     2641 tctaaacgac tctcatctaa ctccaataaa tcaatctgac gactcatatc gccgattgca
     2701 tcttgcagca aatagtaagc actttggata ttttcataaa ttgcttcata ctccacatct
     2761 agatgggcga tcccttgcag ttctgaaacg gccaagccaa caccatctac actgttttgt
     2821 tcattattcg tcagtgctcc gtaacctgca gctaatccat cagcaatttt ttgataattg
     2881 ctaagttttt ctctttcttc ttttaatttc tcttcttctc cgacttgcaa atcagcagca
     2941 gctatttctt cttgctggaa atggagcata tctattctct gaacatagga tttttcattt
     3001 tgctgcactt ttcgtaccct tttttccagc tcacgataag agatatattc ttgctgataa
     3061 ctctttttct tctgttggaa agctacatct ccaaaacgat ccaataaagc aagatgtgat
     3121 tcaggctgga gcagttcctg atgttcgttt tgtccttgga tatctactaa ataactgccg
     3181 attcttctca gattagctaa tgtgataata tgaccattca ctcgacaaac attttttcca
     3241 gttaaggaca tatcccgtcg aacaatcaga ttgtcctcat ctgtttcgat ccctaattca
     3301 accatcagtt cagagaatcc ttcttgtttt ggtagttcaa acaacccttc aagcacacat
     3361 ttttctgctc cttgacgtat ataatcgctt gaacctcttc ctcctgctaa cagacctaaa
     3421 gcatcgataa taatggattt acccgcacca gtctctccgg tcagcgcggt cattccttcg
     3481 tgaaaagaaa gccgcaattc cggaataatc gcaaagttag taatactgat ttcttgtagc
     3541 atcacattcg ctcctcaact taaaggtaat gcaggaagtc tttcttcaat aaaactgcct
     3601 ggtcttcagt tcgtgtaatc atcaaaacat tatcgtcatc attgataatc gaaaataatt
     3661 ctttcttgta acgtttatca atcaaatttg ctgctgccga agcatttccc ggcaatgttt
     3721 tcaaaataac aaatttttcc atttggtcaa ctgccacgaa agcgtctttt aatagttttt
     3781 ccaatttagt atttacatct tcgtttgttt cagctggtat gctataacgg tagccgccat
     3841 ctgaagccgg taccttgatc agtttcagtt cctttatatc tctggaaatc gtagcttgag
     3901 taacagatat tcctttgctt ttcaggattt caacaaattc ttcctgcttt cggatatctt
     3961 gctcactcaa caatcgagta atcaaacgat gccgatcttt ttttctcatt acgtcttcgc
     4021 tccttagcat attcttctta atcaatgata gcttatttcc ttggtataat aaagaagaat
     4081 ccgcatactt ctcacttgat tttcacagtt acaatttatt tatggtcaaa ctgttcgtgt
     4141 gcatttgaaa ccacttctgc catattaata gctgaattga ttgttccgct ttcgggtact
     4201 ttcctcaagt gagccaagaa ctcgatattt ccttctcccc ccgtgatcgg agaataactt
     4261 aattccagca catcatatcc accttgtgcc gcaaatgaca aaatgtcttc taaaactttt
     4321 tgatgggtct gagggtcacg aacaattccg tttttcccta cagcttctct gcctgcttcg
     4381 aattggggtt tgattaaagc aatcacttct ccctcttctt ttaaaatagc atgtaatgga
     4441 ggcagcatca gttttagtga aataaaagaa acatcgataa cagcaacttc tggaattcct
     4501 aaggtaaagt cttcgggttt tgcataacga aaattcactc tttccattac gacgactcta
     4561 ggatcttgtc ttattttcca agctagctga ttgtagccaa cgtctaaagc ataactcatt
     4621 tttgcgccat tttgcaaagc tgcatcagta aatccgccag tggatgcacc aatatctaac
     4681 aatgtttttc cttcaacaga tagatcaaat gctttgagtg ctttttctaa ttttaatccc
     4741 cctcgagaaa cataaggaag ttttttacct ttgactctta attcactact cactggaatt
     4801 ttttctcccg gtttatcaaa ccgctcgttt ttttcgttgt aaatcaaacc agccatcact
     4861 gaacgtttgg cttgttctct tgtttcaaat aatccttgtt tgaccgctaa tacatctacg
     4921 cgttcttttt ccattctttc cctcatttct ccacatcaaa ttgcttgatc atctggcgca
     4981 tcagcccgcc atcaaaagaa aaaacgtcct cttctaattt gtctatgatc ttgttggcgg
     5041 ataacagctc aatctccaac gcctcacgtg tcttttctag gcctaataaa cgcgggtaag
     5101 tatttttttc catacgttca tctttaccag ctgttttccc taatgttttc gttgtaccaa
     5161 tcacatcgag tagatcatct cttatctgaa aagctaaacc taaatgttcg gctaatcgtt
     5221 gaagtagcaa taagatttct tcaggttgct tcgctaatat gccaccagcc agcaaggcat
     5281 aacgaatcaa atgccctgtc tttctttcat gaataaatgc taattcttct aaagaaagct
     5341 ttttcgattc gccctcgata tctgcagctt gcccagcaac cataccttgt gatcccgcac
     5401 aaacagctaa ttgctgaagc agcagaagct taggagaatt acctaagtgt gccatactga
     5461 ttagctggaa tgctcctgta agcaaaccat ctccggccaa tatagctaat gcttcgccga
     5521 atactttatg attggtaggt tttcctctac gaagatcatc attgtccatc gcaggcaaat
     5581 catcgtggat caaggaatac gtatgcacca tttctaaagc agctgctact tgatagacgg
     5641 gaacatcaat aggctcatca aaggaagcaa cggccgttaa aagtaataag ggacgtattc
     5701 ttttcccgcc tgctttcact gaataactca tcgcatcata gagtcctcta tccgttgtat
     5761 gctcatctaa aaaagacaag atttcttttt ctacagcagg tagatgaata gctgaaaagt
     5821 cagttaatct catctcagct ttcctcgttt ccgtcaaaat caacttcttc atttgattct
     5881 gtcatcattt tcgtcaaggt ctcttctgct ttagctaatg tatcttggca atgtttgctt
     5941 aattccattc ctcgtttaaa cgaatctaga gctgattcta atggaacgtc tccttgttct
     6001 aactgcatga caattttttc taattcttgc agtgactctt caaaagttgg attttccata
     6061 tttttattct cctttgtcta tctcttgtac ttgtccttta acgattccat cttgataatg
     6121 gatcgtcagc aaatcccctt gatgaatctc ggtgacactt tttactactt gatcatttaa
     6181 cgtcgtatag ctgtagcctc ttcccatgat tttcaatgga ctcaacaaat caagagattg
     6241 aacagcttga gcaaaacgct gctgctgttg tttcatatat tgttggattt tctcttctaa
     6301 gcgtttttct agataagcag tttcttggcg agctgcttta actcgataaa gcggagccac
     6361 ttgttccaat tggtggctta atgcgatcgt ttgtttttct ttcgcatgat aaatttgctg
     6421 tgtagcttga tataatcgct gtttcaactg gtctaatttg atggtctgac cttcatacaa
     6481 tctttcaggc tgccgaaata cataggaacg tcgagcacgc tcgaaccgtt cttgtttgcg
     6541 ctggatctgg cgtacaaacg cctgctgcaa tctagcttgc cgttcttgaa tgcgcatcaa
     6601 ctcttctgac aaaacaggaa cagctaattc tgcagctgct gttggagtgg cagcccgaac
     6661 atctgctact aaatcagcga tcgtggtatc tgtttcatgt cctacagatg aaatcaccgg
     6721 cgtattagct tgataaatcg cccgagcaac ccgctcttca ttaaacggcc ataaatcctc
     6781 aatcgaacca cccccacgac cgatgatcat tgtatcgaaa ttgcccatct cttctactct
     6841 ctggatattc ctgacaacat tgtccgctgc ttggtttcct tgtacaactg ttgggaacaa
     6901 aaccaattgg acaattggat atcttctttt caccgtcgtg atgatatcgc ggataaccgc
     6961 tccgcttgga ctggtaagga ccgcgattcg ctttgggaaa cgtggcagca tttttttagg
     7021 cccttgaaaa aggccttcct tcatcagctt ttcttttcgt tcttccaatt cttgatataa
     7081 agcacctatt ccatcaggct ccatgtgctc tacatagatt tgataagaac ctcccgcttc
     7141 atataatgaa atacgcccaa cgacaaggac tttcattcct tcttttggct ggaatcgtaa
     7201 tttttggaat gctcctttga acataatagc agatattttt gcatggtcat cttttaagct
     7261 gaaatattga tgggcattgg cacgtaaacg gaaattcgat atttcgcctg ttaaatatac
     7321 gcgttctaaa taaggatcgg catcaaattt tcttttcaaa tacttcgtta atgtagtgac
     7381 agttaaatat tcttgtgcca tctattcacc tgctccaaaa gcttcggcag attttacggt
     7441 ttgatacatc agcatcgtga tagtcattgg ccctacaccc tttggcacag gagtgatcca
     7501 gcctgcaata ggctccactt catcaaattt cacatcaccg atcagcttac cgttagcatc
     7561 acgattcatc cctacatcta tcactacagc acctggtttt acgaattctt ttgtgacaaa
     7621 atgtccacgt cctattgcta cgactaaaat atctgcttct tgtgccagtt cagccagatt
     7681 ttcggtttta gaatgagcaa cagtaacagt tgcatctgcc atcaagagta gctgagccat
     7741 cggtttaccg acgatattgc ttcgtccgat aactactgct cgtttacccg ccggatcgat
     7801 agaataagct tcaaacattt tcatgatgcc gtatggagta caaggaatct tgtccggttt
     7861 acccgcaagg agtctgccta aattcatcgg atgaaaaccg tctacgtctt tttcagggcg
     7921 gatagctaac aggatctttt cttcatctat atgctttggc aatggtaatt ggaccaatat
     7981 accatgaaaa ctaggatctt gattgtattt ttcaatttct gcaagtagtt cgtcttcaga
     8041 aatcgtctca ggataacgct ctaccaatga atggattccg atttcttttg ctacacgttc
     8101 tttatttctt acatagattt ggctggctgg attttcccct accaataaaa cgactaatcc
     8161 gggatggata ccattatctt tcaatttttg gattttttca gcaatctctg cctgcatttt
     8221 ttcagctaat tcttttccgt taatcaattc tgccatctaa ccactcccag atattttttg
     8281 tgttttcatt ctaccataga attttcccga tttataacag gtttatgatg attcatagaa
     8341 aaaagctagg acttacgccc cagcttctaa ttctttcaat acattggata aaacaccgtt
     8401 gacgaattta cgtgaacggt catcactaaa tgtttttgcc aactcgattg cttcatttaa
     8461 agcaacagcc gctggtacat ctgtcacata agtcatttca aaaatcgcga tacgcaagat
     8521 caccaaatcc atttttgaga tccgattgat gtgccaattg ttttttaaat gtttttcaat
     8581 cactttatcc aattcatctt tttttgcaca gacaccgcca actagcgtat caagataaac
     8641 aggaacaaac tctgattcat cttcgttgat catgtcgcgg tggtctaatt cgattgcgtt
     8701 gaaaatcgca tcttcttttg ttaggtctgc attgaagtct aatggaaata aagcctgcaa
     8761 tgccatttcc cgaatctcgt gtcttgataa ttctttattc attctcttcc tcttcgtctt
     8821 caaaaagttc ttcgattgtt ggttgttcta atttttcagg aacaacagct actacatgga
     8881 tattgacttc agataaatcg atatccgtca tgaaaaggac ttgctggctg acccgttcct
     8941 gcatttccat tgctacttta ggaactgaaa caccatattc tagataacag taaagatcta
     9001 ctttcaagcc atcttcctcg tttgctaagt aaacaccttt tccgtgagct gcacgtccta
     9061 ataattcagt gacattgctg gcaaaagttc cgcgcattcc gtatacgcct tctactttag
     9121 aagctgcaat cccgataatt acttcgatga cttcaggagc gatcacgatc tctcctaaat
     9181 cttggtttgc gtttaaaatc aaattttttt catctgccat ttatttattc ctccctttgc
     9241 ctaagcacga gatacatccg aattctctat gatgcggcat agtgatcacg tggtaagaaa
     9301 actgccgccg atcagctgca aactgctatg aattggagaa aacacccaac tttattatct
     9361 cttacagctt aaaagttctt ctatagtgta tcattaaatc gagtgatttt ctataacaaa
     9421 gtctgtgaac actgattttt acgcttactt cttctattga tgaaactata agatgatcaa
     9481 ttcttttggt gaacgagtca acacacgatt tccatcttct gtgatcaaca agtcatcctc
     9541 aatacgtact ccaccgattc ctggtaagta gatccctggt tcatcagtga tcacatttcc
     9601 tggtacaaat tgcttttctg cacgagaaga aacgtttggt ccttcgtgga tctctaaacc
     9661 gatcccatgt cctgtagaat gtccaaatgc ttccccgtaa ccatgttttg aaatataatc
     9721 tctagcaact gcatctaatt ggacaccagt cattcctggt tttgcagcat caataactgc
     9781 taattgagca tctaagacta tttgataaat ttcttttaat ttttccccag gatcaccaat
     9841 agcgaatgta cgtgtcatat cggaaacgta cccttcgtaa tagcaaccaa agtccaatgt
     9901 gatcaagtca ccttgttcga tgattttttt gcttgctaca ccatgcggca tagccgaacg
     9961 caatccgcta gcaacgatcg tatcaaaaga aacacctgaa gcgccaagag aacgcatata
    10021 aaagtctagt tgatttgcga cttcaatctc agtcatgccc ggttggatca ttttcaggat
    10081 gtgatcatat gccatatccg caatatgaca tgctttttcg ataatagcga tttcttcttc
    10141 atctttcact tctctgagtt cttcgatcat ctgtgaaaca ggtactaatt ccgcatcgat
    10201 gatttcttct aaaaccgaat attctaaaaa tgagactgtt gtttcctcaa aagctaatga
    10261 gtgcagttct tctttgcgta ctaagtttgc tacctcatca aaaataggtc cgacattttt
    10321 aataatttca aacccttgag cctgcgctgc cgcctgctcg gtataacgaa aatcagtaat
    10381 aaaaaatgct ttttccaaag taataacagc taatcctgtc gtacctgtaa agttcgttaa
    10441 gtaacgaaga ttgtacggac tggtaaccaa aaatgaatcc aaattttctt cttgcatttt
    10501 tttgcgcaat ttttctacac gtagcatcat aatgaaactc cctctttctt tgcacgcttt
    10561 tttccattat agcaaacttt tcttcgtaca cgacagttaa ataaaaattt ccggaaaact
    10621 tctttttatt ttaaataaat aaagccaaaa aggagtcaca gtctcgctgc aactcctttt
    10681 agtttactat tttgtaaaaa cttatgatcg ttttccaaag aaaaatgaga caactgctac
    10741 caaaatcact gcgcctaaaa tagatggaat aagtgccata cctgcagctt ttggtcccca
    10801 ttcgccgaaa atcgcttgtc caatacttga accgactagt ccagcaatga tattcgttac
    10861 acagcccatc gaatttcctt tactggtgat cgcacctgca attgctccga tcacggctcc
    10921 aacaatcaat gtccataacc aactcataat ataacctcct tctttgctaa tcaattttag
    10981 catatgggat ttaaagggga caaataattg gttttgctat ttcatatttt cttctgcaaa
    11041 gtaaaaaaat aaagaaaacc tcctcttaga agttttcttt attttttact tgcgtttaaa
    11101 catactacga ataccacgtt tcactacatc aaagaaactc aatgattgta ccattctatc
    11161 ttcatctaca tattctctga tcgcacgaag cactttttta ggttctttgg aagaaaatgt
    11221 gtatgtacca ttttttttcg tttgaatggc atatcgagga atccattttc cctttagcat
    11281 gactgatgct agtacataat ccacttcttc ccatggaatt tggatatatt tgcgtctatc
    11341 tcgcgcatgg taaaactcaa aaccattatt acctatcatg atttgcccgt aatctgtcag
    11401 acccgtaaac gaagtagcat caattaccaa gtctactttt gtattgattg attgaaccat
    11461 tttctccctc cagatatttg tttatgaaca gtatactata taaaaaaagc tcgggacaac
    11521 gcccgagcta tatttttatg gattataaaa gtccgatgac gtgtccaaca acaccgacta
    11581 cgaataaacc aaggatgata acgattggag aaaccttttt cttaagcaac cacatacata
    11641 acaatgttaa tcctaatgca gctaaaccag gaatcaattg gtctaagttg tcttgtaatg
    11701 ttgttacctt ttcaggagaa agggctaagc cattattaac ttgttcaaat gcactcttga
    11761 ttccttcacc acctgaaggc aatttatccc attcgatgta agcaccttta tctaatttta
    11821 cagttgatac aactggtaag aatttgattg atacccatct ttgtacaagg gcagctaata
    11881 cgaacatccc taaaattgaa gcaccttttg ttacgtcttg taacaatccg ccagaaaggt
    11941 catcagtaat tttagaacca gctttgtagc caaattcttg tgtataccac atgaatgccc
    12001 aacgaataat gttccaacct aagaagaaga tgattggtcc aaggatattt cctcccatag
    12061 ctaatgaagc acctagtgca cctagcattg gacgtactgt aaaccagaac actgggtcac
    12121 caacaccagc taaaggaccc atcataccta ctttaacccc ttgaatcgct acatcatcaa
    12181 caggcgcgcc attcgcacgt tcttcttcca gagccaatgt aacccctaaa attggagaag
    12241 caatgtatgg gtgtgtatta aagaattcca agtgacgttt taatgctgca gaacgttctt
    12301 cttttgtttt gtataatttt ttgattgctg gaatcataga aaatgcccag ccaccgtttt
    12361 gcatacgttc gtagttccat gaaccttgaa tgaaggtaga gcgccacgca acagctaaac
    12421 gatctttttt tgataatttg attttttctt ctgccatttt attttcctcc ttcaagatta
    12481 atagtcattc aaaatgtcgc ctaaagggtc accagaattg cttccgcctc cattatttga
    12541 tgaaccaccc attttagaaa ggttcaagta aataagagct aatgcaacac ctaaagcacc
    12601 tagagcaatc aatgttaatt gagaaattgc agctacaacg aaaccaataa cgaagaatgg
    12661 ccatacttct tttgtagcca tcatgttgat taccaaagcg taacctacag ctacgaccat
    12721 tcccccaccg atagccatac catctgttaa ccatgctggc attgattcaa ggaatgattg
    12781 cacagtttgt gctgggataa atagcaacgc tgctgctggg accgcgatac gaaccccttg
    12841 taaacataca gcaatgatgt gccacatttc aaccttacgg atgtttcctt cttcagcagc
    12901 cgcatccatc aaatgaacga ttggaacagc gattgtacgt acgatcattg ttaagaacaa
    12961 ccctgcaaca gccaaaggaa cggcaatcgc gatcgcagaa ggaacacctt taacaccttg
    13021 tccacctaaa actaaaataa ttgctgatgc tactgatgct aatgcagcat ctggtgctac
    13081 agcggcaccg atatttgccc aacctaaagc gatcatctga agcgtaccgc caagtacgat
    13141 accagcttcg aggttaccgg taactaaacc gatcaatgta catgccacta gtggttgatg
    13201 aaattgaaat tcatcaagaa taccttccat accagctaga aaggcaacta atacgactaa
    13261 aattattgaa ataatagaca tgataagcct cctataaatt ttaatattat ttattacgct
    13321 tttgctaatt cagcttttgc ttttttcaaa atatcatcca tgttatcgcg tgaatcatta
    13381 ggtactttac gtacatcgaa tttcacacct ttttgttcaa gcttctcaaa cgcttcaacg
    13441 tcttcttgtc ccatagacaa tactttactt acaacgactt taccgaccga atgcgccatt
    13501 gacccaacat ttaattcttt gatgtctacg ccaccttcaa cagctgtcaa tacgtcttca
    13561 ggattttcaa ataaaagcaa tgctttggta tttccaaaac gagggtcttt tgctacttcg
    13621 atcattttgc taataggaat aacatttgct tttacacctg gaggagcagc ttgttcgatt
    13681 agtctcttac gcagatcatc ctttgatact gcatctgaaa caacgataat acggtttggt
    13741 tgcactgctt ttgtccaagc tgtcgcaact tgtccatgta acagacgtga gtcaacacgt
    13801 gctaatacat atttgatttt tccgtctccg accacagttc cttctggaag tgctccttta
    13861 ggttgtgcgt cttcaactgc tgctttcggt gcttctgccg gttctaattc ttccggtttt
    13921 acttttacac cgtcttttgc tgtttcaatg atgtgtgctg caatttcatg agcagattcc
    13981 attgaaaagc gtgatgcgta ggcttcaatc aacattggta aattcaaacc gctgacgatt
    14041 gcccatttat ctttgtgctc ttcgaataat gtgtttgatt gattgaacgg tgttccgccc
    14101 cataaatcaa ctaagaataa cacttcgtct tgattatcaa aagaagcaac cgcttcttcc
    14161 aatttggctc tcaagtcatc tggaccttca cttggtttca aaatcacggc tttgacgttt
    14221 tcttgttcgc caaagatcat tgaaccggat tgtaagattc cttcagcaaa ttgtccatga
    14281 cttgctagga taatccctac catatttata cctcctattt acttttgttg taacaaattc
    14341 aaaaatatta ataattgcta accattacaa cagaattatt tgaccttttc caacaaccat
    14401 tcttgctaca cctttttgat tttcgctagt agttccatca aaaggatttt cctgtcagca
    14461 ggtacttttc gaatctctaa ctccacttct tgactgttca agtaacgaaa ggaatcaata
    14521 tcttgttgat ttactgaaac aaaattggta atcattgatt tgccttcagt aaaactcata
    14581 ccgccgatat tcaacgactt caactgtaca ccgcagcgga caaccgcttc aacatcttgg
    14641 ggattggtga ataaaagcat cacttttgct cgtgataata atccactatg atagatttga
    14701 atcattttct gcacggttat tacatttgct gtgatccccg gcggtgcagc ttcttttagt
    14761 agaaactttc tcaatttatc ttgagcgact acatcgctga tcacaatgat acgttcaaca
    14821 cctgtttgct tcgaccaaac tgttgcgact tgcccgtgga ttaaacgatc atctatacgt
    14881 gccaatcgaa tatccatctg caaaactcct tcttcctcac tacttcacag aaacccctat
    14941 catttctgtg tgaacaacca cctcctagca cacactacta taagcaaaaa gcgtgccaac
    15001 ttttttacga tacactaatt gaatttaaag gattcttaac caatacacaa aaacgataca
    15061 ctataaaagt gtatcgtttt tgtgtattca tggcacagtg tattcttttt tatctaactg
    15121 attatggact agacgtagca gataatacat ttcttctatc ggcactttta cttttatctg
    15181 atcttccaac agaacaactg aggctgccaa ttggctataa agaggatcat tcgttgtatt
    15241 tgtcaattcg ttttcttcca cagtcaatgg ttcattccga ataatacgtt cgatcattcc
    15301 tgctgtgtgc atcactaggt tgattttgaa tccatattct tcatcgccga ttcccgtcgt
    15361 ctgagagatt tgtgtagaaa attgccacat tggatcgatt aacttactac cattaataaa
    15421 gatgaagtta tcagagataa actcaacaca cgtattttta gctgactctt catctaggga
    15481 gatgaattca gtttcctcca attctgattc catcagcaac tgatccaaaa tgacttcgat
    15541 attttgatca ataaaacgtt ctaaaggaat aaatggggct tggatattca aatcagtaat
    15601 cccagtagta gctatgatct gatattcttt ttggataact ggcagttctt ctttcacttc
    15661 cacaatcgac aaagctagaa cttctaattc tgtttcttga cgcttgttta ccgctcgttc
    15721 gatcaattct ttgattcttt gtgctgtacc ttcgccagat gcgcagatag ccaaaacagc
    15781 ttttttctta tgaataggtt ttgcttcctg aacagattct acagaagata tttctgcgta
    15841 acctcgaaaa tttttcaatg attcatgcaa catatctaga tctgtcccta atactgagac
    15901 ctttcgtaca gtttccaaaa ctagagaagt tgttaccata tcaacagtac gtactggaat
    15961 tccagtgtct ctttgaattt gcgaattaaa cgacgcaagg gaccccatat ctactaagag
    16021 tatgaccccg cttccttcat ctacttcttg tacattgcgt tcaattcggt ccaatgctgt
    16081 tttcggatcc atatccaaag gcatgtctac tgctcgtacg ttctctgcat ctaacaactg
    16141 ttggacaact tggaccatac tgcttgctgt gctgtttccg tgagctgcaa cgactacacc
    16201 gattctgccg cttgcttgat ttgcccgtaa cgagacgagt agaacggtca agtaatagtc
    16261 ttcactttct ggaatctcca cttgaaaata cgtttcgata taactacgca cttctttcgc
    16321 aacagcatat tcatctggaa aatcaaaagc catctcacgg atgttatcat tcgtatgccg
    16381 ttcttctcct aagttgattt ttttcaaaaa agaactgata tgcaagctca tagcataaat
    16441 aaagttttgc tgaaactcat atggtaaaga tcttttgacc attacataaa tctgattggt
    16501 cacttctatg attttcggat ctacaaattc tgctaatttg ctgtctgcat taaaagaaaa
    16561 accatggtct ttatagaaag acttcagatg gatgttgata tctgtagaaa tgaaatgatt
    16621 gattgcttct tgatccaaac catccgactt cagtaaagct gctttatctc cgatgatatc
    16681 atatagatta taaggtaact cataggagtc cgattggatt ttcatgatcg tatcatttgg
    16741 tgctacagtt atctttggct ccaatatttt agaaagctct gccattgcac tgcggttgct
    16801 tgctaattga atcaatccgc tacgaatccc ttctgtcaaa tcatcgattg tgatcgagat
    16861 ttcgggtgat tgcatatgat ttagaaatcc tcgtgcacat actaactgga tatttgactt
    16921 caattgtcct atatttccat aggtcacact gccgatcaat gcttttgcta catcttctgt
    16981 caaagaaatc tttcgctgcg tgcggtttgc ttcgtgggca atcatgattt ttactaaatc
    17041 gactttctca tttgcaggac gtttttcaaa agccggaagt ttgatattga ttgggatacg
    17101 ccgaacaaaa gtttctaata gagaagaacc tgggtcttct gtggtcgcac ctacgatccg
    17161 tacatttgct tcatgggatt tcgttgtttc cccaagacga ctgtaagttc catgatccat
    17221 aaagtaaaag atcatttctt gaccttcagg cggcaaccgg tgaatctcat ccaaaaacag
    17281 cataccgcca tccgcttgat cgataatccc cattttttct tcatctgcgc ctgtaaaagc
    17341 accttttgcg tacccaaata aatgactcat caaaagctca gggttattgg cataatcagc
    17401 acaattgaaa acaatcagtt ccgtttcctc atctattaca tgatgcgctt ttgcaaaatg
    17461 atacatcgcg tgtgcaaaat aagtctttcc tgatccggta ggtcctgtaa tcaaacaatt
    17521 taatcctctt ggcggataca aaatcgcagc ttttgcctgt tccactgaat ttttcatgct
    17581 gccgttagct ccaatgattt ttgcaaagat atccttagta tctatttgga gtgtattttt
    17641 ttcttcagag accggcgttt ctttgtaact gactacatgt tttgtaactg gctttacgtg
    17701 cgtaacgagt gtttgatata tgtaacgtac tggtcgtccg tctgtcttta tcagttttcc
    17761 ttcgcgcact agctgattca gatctttact gctatttgtt cgctgaatcc ctaacacttc
    17821 agcaatttcc tgtgttgtta ctccttgatc atattctgcc tttgttaaat gagcggtttt
    17881 ttctttgaca tacatataaa ttcggtcaat gcgttttgcc aatggtatcg ctccttttct
    17941 atagactatt gtacttaggc ttcaaaacat aatactatgt atttatttct gtttcgtcaa
    18001 ctatttacct gattttgttt tgttgataac acgcggatag atagaaatgt tcaatttaaa
    18061 agaacgaaaa atcccgatac gatttttata atggaaacaa gaaaaagaac actgtttacc
    18121 atataattat ttcactgata gcaaacaata tagcttccat caattgaaaa cgatagttat
    18181 caaaacatcc tgattccaaa ttggcaaaaa aatattaagt gtaaaaagac aaagtaaact
    18241 tcgtagcctc cactacaact tttattttta taaacaaaaa aggctgtgac aaaagtcttg
    18301 tcacaacctc tttaatcata agattcaatt aagcttcttg agctactgga taaacagaca
    18361 cttgtttttt gttacggcct ttacgttcga aacgtactac gccatcaact tttgcaaata
    18421 aagtgtcgtc tccaccgata cccacgttta cacctggata gatttttgta ccgcgttgac
    18481 ggtaaagaat tgatccacct gtaactgttt gtccatcagc acgtttagca cctagacgtt
    18541 ttgattctga gtcacggccg ttagatgtag aaccgccacc ttttttgtgg gcaaataatt
    18601 gtagattcat agataacaac atggtctgca cctcctattt atcattaatt gttttaattt
    18661 ggatatattc tgagttttca gcttctatcg attgtaatcc taataaaaga ttttctaata
    18721 gaatctcagc aatattgttt tgttcttgtg tcattcctga agtgacttcg gtataaagat
    18781 aaccgccttc ttcttcattc atttcaacaa tcggctcaaa accggctaat gaggcaatcc
    18841 cgttgacagt gctgatcgct aacgcagaaa cacccgcaca aacgatatca cttccataag
    18901 gaccagcatc agcatgcccg gtcaaagtga atgaaacgat ctgacctgcg tcatttcgct
    18961 taaatgttcc tttgatcata tataggcctt ctttctcaaa cgctattaag cgttgatcgc
    19021 gtcgataacc acttttgtat atggttgacg atgaccttgt ttacggtgtg aatgtttttt
    19081 aggtttgtat ttgaaagtaa cgactttctt ttgtttgccg tgtttttcaa cagtaccttc
    19141 aacagttgca cctgcaacag ttggagcgcc tacttttgta gattctccgc ctactaagat
    19201 aacttcgtca aaaacaactt tttctcctgc ttcaacgtca agtttttcaa catagattgc
    19261 ttgtcccact tcaactttta cttgtttacc accagtttta ataattgcgt acatgctata
    19321 aagcacctcc ttctgatata cttagactcg ccatccgaag tgacagcata tgctgtgctt
    19381 attacttgtt ctgagcggtt gtagctgtgg agtccacaat tacaacagta ctagcttacc
    19441 agaacagcaa ccgttagtca actaaattta aaatcaaaaa gtaaaacaaa aattcaagca
    19501 atacttctgc ttttctatcc tcacagttct accaaataaa atagtcgcat tgtgtttctt
    19561 ttattcttat aataaaagaa aaaggaggag cataaatgga atacccaaaa gaactgatac
    19621 aagaagcttc tttaagaatg aacggccgtc ctgtagaagg atttatcgct gggcaaggac
    19681 ctcttcatcc taaactgatg ctcgtgggag aagccccagg gaaaacagag attgatacgc
    19741 atgttccttt tagcggtcaa gctggaaaag aattgatgca ggcactttct tcaactggct
    19801 taacacgaga agaggtgtat atcaccagtg ctgtaaggag ccgcccgtat cgcgtgactc
    19861 atcggatcaa taaacggaca caacagtcag aaactgttta tccaaatcgg acacctactc
    19921 gttccgaagt atttgcgcat gcaccaatat tggattacga actgatgaag gtccagccaa
    19981 aattaattgc gacacttgga aacattggtc ttcaacgttt acttggcaaa gaatatacgg
    20041 ttaccaaaaa tcatggtcaa ctctatacag ggcctgtctt acaattaaca gaacaaaagg
    20101 atgcctacga atggtcagaa aaaaactatc gaattcttcc actttttcat ccagcagcta
    20161 ttttctacaa tcgctccctt gtacctgtta tccatcaaga ctggcaagta ctagcttcac
    20221 ttttacagca atattaaaaa gaacagacaa gaccataaaa tcttcagttt acagtcttgt
    20281 ctgttctttt tcattgtttt aatggctaat tgcagtatat ttcgcatgta aagctgtcaa
    20341 cgcatgagca actgtttgat gttgatgcgt gaatgtatgt tcccacaagt gagaaagttg
    20401 tttttctact tctggctgca aggaagtata gataatcgtt tgtcctcttt gctctgcttt
    20461 ttcttgaaat tcatcaaaaa ctgcacgtgc cgtcaaatca atacttggta cgcctcgcat
    20521 ggagaaaatg acaccatcgt gatgatttag ttcttccaat ttatttttga gtttttctga
    20581 agacataaaa aacagtggac cactaatata cactactgtc cagttattca gcttttccgt
    20641 ttctggcagc cccattcttt gccaatcgat cgtttctaat gaaatcgtga tagcagcgct
    20701 tttgacaaca aaaaatacac agccgccgat caccccgatc acgatagcaa tacttaaatc
    20761 aaagataact gtacaaatca tcgtaaggat aaacaataga actgctgacc aatatttatt
    20821 agtaaatagc tccttgatcg tttcccattc attcatacgc caagccgtca caatcaaaac
    20881 acctgcaagt gctggcattg gaatctgtga catcactggc gcaaaaacaa gcatggagag
    20941 cagtaagaca actgcatgta tcataccagc taatctagtt tgtgcaccag atttgatggc
    21001 cacgcttgta cgggcgatgg ccgcagtagc aggaatcccg ccaaagaaag gaagcaacag
    21061 atttccaatt ccttgcgcca ttaattcttg attgctatct aagggcttat ttgccattcg
    21121 gccagccgaa gcaccacata gcaagctttc aatcattcct aataaagcaa tgctaatagc
    21181 tggaactgcc acttgttgca aggcagaaaa gctaaaatct cccatattca aacgattact
    21241 actgatcaat gtttgtggaa tcttacccac agttgctact ggtaaatgga acaatagcat
    21301 aactgctgtt gccaaaatga tagccagcag cgaactaggc attcgtttcg cccatttttt
    21361 tggatagata aacatcccta aaatgactag ccctcccatg atcaaagagg ctgtgtttat
    21421 cggaaatcct atcgtttgat aactacttag tttttcaata acgtttgtac cttccgagtg
    21481 aacaccaaat aaattatcga tctgacctaa tgcaataatg atagcaatac ctgaagtaaa
    21541 ccccgtaatt acgggtgctg ggataaaaga agtcagtgtt cctaatcgga aaagtcctgc
    21601 tgcaagtaaa aatagacccg ctaaaaaagt agcaagcaat acaccttgca ttccctttgt
    21661 tgccgcaata gacatcaaga tagctgccat cgcacctgtc ggacctgata tttgataaaa
    21721 accgcctgat aaaccgccaa taacgatacc ggcaatgata gccgtaatca aacctgcggc
    21781 cgcatcagct ccgcttgata ccccaaaagc caaggctaaa ggcaatgcta cagcagctac
    21841 tgtgatccca gccaaaagat ctttctgaaa tcttgaaaga tcataacctg aaaattcttt
    21901 ttttagtgag gaaacataat ttttgaacac ctatctaact cctttttcat gaaattttct
    21961 aaaataccat tcattagaat atcatatttc atgagataaa gtaatatttt tcacaaagtt
    22021 tcctgttaga taaattctta ttttttctat atttataaga aaatagaaag caatgccaac
    22081 agagctagcc caccttgttt gagtaaaatc caacgatcgc tagtcaaact gccatataat
    22141 gcaacaaaaa aaatagatat taatagcata cttgtgattt ctttagatgc ggaagaaaga
    22201 taagctccat aaagtagtcc cactcctaat agtccattgt acactccttg gttcttaaac
    22261 aatgtttgaa cagattttct gcttaactct tctttactca ttttaaaaac cctacttgtc
    22321 gtgtcagaat cagttctcac cgtttcgata tacatgatat aaaaaaattc aattgcaact
    22381 agagtcacta aaattctaga tagtatcgtc atatcttctt cctcttttct gatgagtttt
    22441 atttttttgc tccttataat tgtactcgat aaggatgttt ttttatttta tttgcctttg
    22501 aaaacaaaca atattggcac aaaaaacaaa gaaaaaccgt tagaaacctc agtttctaac
    22561 ggttttttag cgtcacagga gggattcgaa cccccgaccg tccgcttaga aggcggatgc
    22621 tctatccagc tgagctacta tgacaagaat cagcggaaca tcaataatta tagataatta
    22681 aattgcttct gtcaatacga aatagttatt taattagcaa ataatgaatt attttggccc
    22741 aactactaaa tcaatctttt aaaacgagac attctccttc agctgttcta aggttatcaa
    22801 ttgaaaacag gagctacatt gacttcatgc tactcctgtt tatttagatt tcctgtatcc
    22861 tttaattgac ttacaaatat agaaactttt acatcaagtt cgaattgagc cctcgattca
    22921 atcgattatc tacaggctgc cataatcatg tatcacaact cgattgtttc tgattccttt
    22981 gtcattaaga tcacaccatc acctaatggc aagattgtcg atgtcaaatc gggatgatcc
    23041 atcacaacac gaagaaattc atttaattta cgatggatag ctcgtttgcc acggggaatc
    23101 tcttcatctg ggagcaagat cgttcctcct tggaagatgt catctaccat caaaacgcca
    23161 ccttttctta acaaacgtaa gcattcaggt aaaaattcaa tatattttga ttttgcacta
    23221 tccataaaaa taaagtcata cggaccagac aactccggca agatatctgc tgcttgacct
    23281 tcaagcaaag tcactttatc tgtcagtcct agacgttcat agtttttttt agctttctcg
    23341 atcatgacat cgaaacgatc aattgtcgta acatgagcgt tttctccgat tgtcgtggcc
    23401 atgacacttg atgaaaaacc gatagctgct ccgatctcca agattcgttc aggctgaagc
    23461 tgtccaagta aaaatttcaa aaatacaact gtttcatggg gaataactgg tacttctgct
    23521 acatgagctt cttcttccag tttgcctagc tcacccggta attttttttg ctgggtacgc
    23581 ataaaatcca atagttcttc tttgactaca ggacgatgca tcatttcatt gcgcatacta
    23641 ctcctcctct tcacacatta tacgaacaac tgactaaatc tacaagctgc atgagtgttt
    23701 tctcgtgttt catgttcaga agagtcgttg gatctctgga atacatttat gtttttaaca
    23761 ttcttacaaa aatttctgtg ttcgtctccg cttctttttc aactctacaa aggtattcca
    23821 tgctgtgatt cctgttaggc aaaaagcaat cgtaaagaat aacccctgaa tccatgcaaa
    23881 tgccgttttt gaaaggacta gtccaatata tggaatctga aagatgggac taccgataat
    23941 atttctcttt tttactactc caggctcaat ataagtcttt gtatcagctt ttgtataaaa
    24001 atcttcgtgg ttgttttcaa cggctattac gcgacgcgtc gagatttttt ttcctgaatt
    24061 ttcataatat gtaataatat ctccgactaa aatctcattt gtatttttcg gtcgtacata
    24121 tatcagattt ccttgtgcat aatatggact catttctttg tcctcaataa tataaggagt
    24181 caaaccaaaa attcggggaa ccaagacgac gagaagaata agaattaaaa atataatcaa
    24241 cgttatagaa cttataaaag ttattttttt gtaatcaggt atcgttttca acttctttct
    24301 ttattcaatc cttcttaatc atataataac gataaatttt ttcaaattat agctgtaaaa
    24361 atgtttccct ttaataatta tatgtttcta attctatttc ctcatcttta tctcattttt
    24421 tattataaat aattgacgtt agtttaaaaa acgtttaccc taacattaca agttttagaa
    24481 aggaatacct ttatg
//
LOCUS       DADGHT010000037        24255 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.037, whole genome shotgun sequence.
ACCESSION   DADGHT010000037 DADGHT010000000
VERSION     DADGHT010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.037"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(42..1337)
                     /gene="purB"
                     /locus_tag="JX887_001343"
     CDS             complement(42..1337)
                     /gene="purB"
                     /locus_tag="JX887_001343"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAX1257342.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1350..2483)
                     /gene="purK"
                     /locus_tag="JX887_001344"
     CDS             complement(1350..2483)
                     /gene="purK"
                     /locus_tag="JX887_001344"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAX1257343.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2467..2955)
                     /gene="purE"
                     /locus_tag="JX887_001345"
     CDS             complement(2467..2955)
                     /gene="purE"
                     /locus_tag="JX887_001345"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAX1257344.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3371..4678)
                     /locus_tag="JX887_001346"
     CDS             complement(3371..4678)
                     /locus_tag="JX887_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAX1257345.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4681..5262)
                     /locus_tag="JX887_001347"
     CDS             complement(4681..5262)
                     /locus_tag="JX887_001347"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAX1257346.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5378..5475)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5834..7126)
                     /locus_tag="JX887_001348"
     CDS             complement(5834..7126)
                     /locus_tag="JX887_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1257347.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7123..7746)
                     /locus_tag="JX887_001349"
     CDS             complement(7123..7746)
                     /locus_tag="JX887_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257348.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7749..8585)
                     /locus_tag="JX887_001350"
     CDS             complement(7749..8585)
                     /locus_tag="JX887_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1257349.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8602..9489)
                     /locus_tag="JX887_001351"
     CDS             complement(8602..9489)
                     /locus_tag="JX887_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1257350.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9505..10788)
                     /locus_tag="JX887_001352"
     CDS             complement(9505..10788)
                     /locus_tag="JX887_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1257351.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11471..12154)
                     /locus_tag="JX887_001353"
     CDS             complement(11471..12154)
                     /locus_tag="JX887_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAX1257352.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12172..12789)
                     /locus_tag="JX887_001354"
     CDS             complement(12172..12789)
                     /locus_tag="JX887_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAX1257353.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12799..13623)
                     /locus_tag="JX887_001355"
     CDS             complement(12799..13623)
                     /locus_tag="JX887_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAX1257354.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13616..14176)
                     /locus_tag="JX887_001356"
     CDS             complement(13616..14176)
                     /locus_tag="JX887_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257355.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14350..15306
                     /locus_tag="JX887_001357"
     CDS             14350..15306
                     /locus_tag="JX887_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1257356.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15611..16567)
                     /locus_tag="JX887_001358"
     CDS             complement(15611..16567)
                     /locus_tag="JX887_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAX1257357.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16671..17273
                     /locus_tag="JX887_001359"
     CDS             16671..17273
                     /locus_tag="JX887_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAX1257358.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17361..18860)
                     /locus_tag="JX887_001360"
     CDS             complement(17361..18860)
                     /locus_tag="JX887_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAX1257359.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18876..19400)
                     /locus_tag="JX887_001361"
     CDS             complement(18876..19400)
                     /locus_tag="JX887_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257360.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19698..20447
                     /locus_tag="JX887_001362"
     CDS             19698..20447
                     /locus_tag="JX887_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAX1257361.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20438..21223
                     /locus_tag="JX887_001363"
     CDS             20438..21223
                     /locus_tag="JX887_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAX1257362.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21192..21908
                     /locus_tag="JX887_001364"
     CDS             21192..21908
                     /locus_tag="JX887_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAX1257363.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22010..23029)
                     /locus_tag="JX887_001365"
     CDS             complement(22010..23029)
                     /locus_tag="JX887_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAX1257364.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23048..24106)
                     /locus_tag="JX887_001366"
     CDS             complement(23048..24106)
                     /locus_tag="JX887_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAX1257365.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
BASE COUNT         7188 a         5222 c         4225 g         7620 t
ORIGIN      
        1 ttgctattct attttaattg aattttgcaa ctcactcttc tttattccaa acctactcgt
       61 ttgaatatca cgtcaacgtt tttcaaatga tgatgataat caaaggcatc gtctatttct
      121 tctttagata ataccgatgt gatggttgga tcttcttcta acagcgggcg gaactgcact
      181 tggttgtccc aagcgtacgc agtttttggc tgaacaagat cataagcttc ttctcttgtc
      241 attcccttat cgatcaattt cagcataacg cgctggctat aaatcaaacc aaatgttgca
      301 gacatattcc gcttcatgtt ttcaggaaag accgttagat ttttaacgat attgccaaaa
      361 cgatttaaca tgtaattcaa taaaatcgtg gtatcaggca agatgattcg ttctgctgaa
      421 gaatgagaaa tatctctttc atgccataat gtgacatttt cataggcagt gaccatgtgt
      481 ccgcgcacca ctctggctag accagccata ttttctgaac cgatcggatt ccttttgtgc
      541 ggcatagcag aagaaccttt ttgacctttc gcaaaaaatt cttctacttc acgtgtttcg
      601 gatttttgca atccgcgtat ctctgttgca aaacgttcaa tacttgtagc aataagcgcc
      661 atcgctgaga aatattcagc atgtagatcc cgagggagaa cttgagtaga gatttcttgt
      721 ggacggatcc ccaattgttt acatacatac tcttcaataa atggcgggat atttgcgaac
      781 gttcccactg ctcctgagat ttttcctgct tctactcctt ttgccgcatg ttcaaatcgt
      841 tcgatgttcc gtttcatttc tgaataccat gtggcaagtt tcaatccaaa agtagttggt
      901 tcagcatgga caccgtgtgt ccgacccatc atcactgtat atttgtgttc ttttgctttt
      961 tcgccaatga tttccgtaaa acgtttcaag tcttcccgta aaatatcatt tgcttgcttg
     1021 atgagatagc cataagcagt atctacgaca tccgtacttg ttagaccata atggacccat
     1081 tttctttctt ctcccaatgt ttcagaaacc gctcgtgtaa acgcaacgac atcatggcgt
     1141 gttaattttt cgatttccaa gatccgatcg atatcaaatg atgcatgctc acgaattttt
     1201 ttcacatctt cttgcgggat ttcaccaagt tctgcccaag cttcatctgc taaaatctcg
     1261 acttcgagcc acgcacggta tttgttctct tccgtccaga tattccccat ttcagggcgt
     1321 gtataacgtt ctaacatgtt ttttctcctc taatcccaaa tattcgtttg tttgatttct
     1381 tccagcgttt gctggatgtc ttctgtcaag atagtgatat gtcccatctt gcgacctttt
     1441 tttgcttgtt tttttccata gaaatggaat tgccagtctg gcttattctc aatcaagcga
     1501 tagctttcca gcagttgttc tcccaaaaca ttgaccatta ctgcattgct tatcaaacgt
     1561 actttttctc ctaatggcca accacaaata cctcgaatat gggcatcgaa ctgactcata
     1621 gaacaagctt caatagaata atgtccagaa ttgtgaggac gaggagctaa ttcattcaca
     1681 tatagcccgc ctgtttttgt taaaaacatt tctaccccta aaacacctga aaggctcact
     1741 gcttctgcaa tcacacgggc aatacgctca gcctcctcga tcacatcctg atcaatcgcg
     1801 gctggagcaa tcgtttcatg aagaatattg ttgtggtgga tgttttccac gaccggaaaa
     1861 gtcgtgaaat ctccttgacc atttcctgcc accatgatcg aaatctcttt ttcaaacggg
     1921 atccatgctt ctaaaacaca ggttccttct cttaaaaggt ccatggcagg agctagatcc
     1981 gcccgacttt tcaaaacata ctgccccttg ccatcatagc cgcctcgagt ggttttcaaa
     2041 acacaaggat agccgatccc gtcaatcgca tcttggatat ccgtcggact gacgatcgtt
     2101 gcataaggag caatcacgat gttattcgtt tccaaaaaag atttttctaa caggcggtct
     2161 tgcgtaatcg caagcaagtc tgtcccttga ggaataaatg acatgggtaa aatcgcattt
     2221 aacgcctcta cactgacgtt ttcgaattca taggtaatga catctgttct tctggcaagc
     2281 tctttcagcg caaaggtgtc atcatagaca ctttcaatgt gccaatctgc aacttgtgcg
     2341 gctggacaat cgctcacagg atccagcaca cctactttaa agcccatttc ttttgcacta
     2401 atcgccatca tacgacctaa ttgaccgcca ccgacgatcc cgatcgttga accaggcaac
     2461 aaaggtttaa ccaagttgat cactactttc tataacagtt ttagccaaca ttgaacgtct
     2521 ttcagccaat ttagcctcca attctaaatc atacatggaa agcatctgta tcgcaagtag
     2581 tccagcatta attgctcccg cttttccgat tgctgtagta gctacaggta ctcctccagg
     2641 catttggaca atcgaaagaa gcgaatccaa accatttaat gttcgtgatt ggaccggtac
     2701 accgataacc ggcaaagttg tttttgatgc gaccataccc ggcagatgcg cggctccccc
     2761 tgctcctgca ataatgattt tgattccttt ttttcgagcg ttttgtgcat attcaaacat
     2821 caaatctggg gttcgatgag cagaaacgac ctttttttca taagacacac cgaattcatc
     2881 caatatttga catgcttctt tcattgtttc ccaatctgaa gtactcccca taatcacaga
     2941 gatttttgct gtcattgttt ttcctcccag tttttctaca ttcatatttt aacaatcact
     3001 ttttttgatg tcaaagaaat ttcgaatgtt aacaaagaaa aacattttat tgttcgtgtt
     3061 tattaaagat aaaaaaaagg aatgtgacaa aagttaggtc acattccttt ttatggataa
     3121 acggtgttct cctgccaact cctcggtcac aaggaacaat attcaacaaa catgagaagc
     3181 ttttttttga aattgttcct tgtgactcgg agatgaacgg caggctcacg acctcttcct
     3241 tcaacggtgt tcaatcagct gaccctcggt attagctcaa acaaacggca aaatacgagg
     3301 aactattttt ccgtttgttt ctctaacaat caggtcaaaa cgctgatttc acaacctttc
     3361 ttttgctcta ttacttcttg aaggcttctt ccaatatttc ttcatctttt ttcaatccat
     3421 taaagatcaa attcaatatg atagccgtaa tgctactcat tacgatgcca tttccagtga
     3481 acatttgcaa tgtttgcggc atttgactga ataatgtcgg cgtaacattg aaacccagcc
     3541 caaatccaac agaaacagca acaatcaata gatttttatc attgctgaaa tcaacttcca
     3601 acagcatacg gattccttgg actgccacca tcccgaacat gactaacatt cctccaccaa
     3661 gtaccggctc agggatgatt tgtgctaacg caccgatttt agggaataat cctaaaacaa
     3721 tcaagaagaa tgcagagaaa tagatgggtt ttcttgtttt gattcccgaa agttgaacca
     3781 atccgacatt ttgagaaaag ccagtataag ggaatgtatt gaaaataccg cctaagataa
     3841 cggcaagtcc ttctgcacga tatccctttt tcaattcttc ttctccaaca tttttcccag
     3901 taatgtcacc aagtgcaaaa tatacacctg ttgattctac catgctgacc atggaaatga
     3961 tgatcattag taaaatcgac catacgtcga aagttggttt accaaaataa aagggttgtg
     4021 gaacatggaa caacggcgca tctccaatcg cgctcagatc aatcattccc atgaaagcag
     4081 ctaagatgct tcctccgact aaaccaatca ataccgcgat tgaacgaatg aacccttttg
     4141 ccagcatttg cacgcctaca attaggagaa tcgtcacaaa tgcaagtagc agatttgttt
     4201 tgtcaccaaa atcagctgct gttgcattac ctccacccat tttctcgatt gctacaggaa
     4261 tcaaagtcaa accaataacg gtgataaccg ttcctgttac tataggaggg aatagttttt
     4321 taattttaga aaagacacca gaaactaaca caacaaagat cccagaagcg ataatagatc
     4381 cgtagatagc tcctactcct tcattggttc cgatcaagat cagtggagct actgcttgga
     4441 tcgcacatcc taaaacgaca ggcaagccaa ttccgaaaaa tcggttaact gtcaattgca
     4501 ataatgtcgc taatccacac ataaagatat caattgaaat caaataagtc atctgttctt
     4561 gattaaagcc tagtcctgta ccgatcaaaa gaggcaccgc tactgctcct gcatacatcg
     4621 ctagcagatg ctgcagccct aaaaccgcag cttttccatt ttgtgtttct ttttccacga
     4681 ttatgcgtcc tcctcaagaa actcaacttg tccattcgtc aaggaagcaa tacgcgcaag
     4741 agaaacgact ctcaatccca tttcttcaag taactgacgt ccatcttgga aagacttttc
     4801 gatgacgatc ccgattcctt ctacttgcgc tccagcttgc tggcataatt cgatcaatcc
     4861 ttttgccgct tgtccgtttg ccaagaaatc gtcgataatc aatactttgt cttctgaaga
     4921 taaaaattta cgagaaatag aaatcgtact tgtcacttgt ttcgtaaaag aataaacaga
     4981 agctgtcaat aattcttcat ccatcgtcaa actttttgct tttctagcga agatcattgg
     5041 aacatctaat tctcttgcag caaataaagc tggtgcgatc ccagaagctt caatggtcac
     5101 aactttcgtg attccttgtt ctttaaatac ttctgcaaac cgttttccca tttgttccat
     5161 caatacaggg tctacttggt gagtgacgaa gctgtcgact tttaatacgc cctcgcctaa
     5221 tatacgtccg tctttttgaa tacgttcaac taattctttc actttatttg ctcctttatc
     5281 atttattaat accgaaataa ccgcttttgt gcaaaaacct actatgtttc tgttaaagaa
     5341 aaacaccctc cactttatca taagaaaaga agggtgaaat agccaatctt ttacttatag
     5401 tccagcattt acggtactgg ctagaaactg tcatccatat tatgacgata tataagtagg
     5461 tatgtaaaac taataatagt gtaaattcat tttcttgcaa ctgttttgca cgtgaaggca
     5521 gtttgccata tttgaataaa aaatgttgtt tcaaatattg aaaacagtct aacactactt
     5581 tctgaaactg acaacgtggt ttacttattt ttttgtaaaa tctaatgatt tttaatgcat
     5641 tattcctttt tgttcgggtt taaatagtta tttttatttt ctcctatcta aaaaagcagc
     5701 ccacataaaa agaaggcatg acaaaaagca tgtcatagcc cctttttccg aataaatagt
     5761 gttcaaaaga cagcctatcg gcaataaggc aagattttat aaactacggg aagtaatttc
     5821 cgtaaatcta ttcttattct tttaagctga caagctcgtc aatcactact gcttttcctg
     5881 aagcaataga atgatttgct gcgattcctg tcaaaatcga caaaatacca tctacgtgag
     5941 ttgctgcccg attccacgga tcttcttctt tttcttcacc aaatagatca tctaataaac
     6001 gcggatctcc tccgccatgt ccgcccgctt cttgttcgac gattacctca tatggctcac
     6061 cgaacatcgg atagacatgg atggactgaa gaacggctgc tccttcatcc tttttatctc
     6121 cacctgcatt gatgtaagac ttttcgatca ctttcatttc gatccgtcct ttgctgccat
     6181 tgaaagaaac attgaatcct tcccacggca tatacgcgtt tagcgaatac gtcaaaatcg
     6241 caccagtttc atatttgacc gttacgccta gtgtatcttc aatagagata tcatcggaaa
     6301 atacactgcg gtcacgaata tatccactgt ctttttctgc ttctaaatac atttctcgca
     6361 attcctcatt ggctgacagg tctatagcaa atggatcagc tttagctagt tcgcttccat
     6421 agcatcgact gtaaaatatt tctactccgc gtttctccgc attatgcatc ccataaaagt
     6481 ttaatccacc gaatgcaaat accttttggg gacggctgtt caaccaaaaa ttcactagat
     6541 caaaatgatg ggtagattta tgaacaagaa gcccgccgct attgtgctta tttcgatgcc
     6601 atcttctgaa ataatctgcc ccgtgttgcg tatttaacag ccattcgaag tggatagaaa
     6661 acacatcacc aatcacatca ctttctatca gttcctttat cttcgtgtga tacggtgcat
     6721 aacgataatt aaaagtgact cgcaggcttc ttcccgtctg tttttggacc gttattattt
     6781 cttgagcttt ttcctcatcg atagtcagag gtttttcgca aataacatca tatccttttt
     6841 tcattgcacg aatgatataa tcatgatgcg ttcgatctac tgacgtaata atgacttcag
     6901 ccggccgtac gtcatccagt agttgctcaa attgtgatgg catacatgtc tttacttttt
     6961 tctgtccata cttgttcaca agtatccgat ttgcataatc catccttgtt tgagatacat
     7021 cacaaaaacc gactagttca caagtttgat gatacgtaga ggcaattgcc tcataaaaaa
     7081 aacgcgctct cccaccaagt ccgacttgta catatttttt cttcatttaa agtcattctc
     7141 cttttctttt aagcaaaata ctgtgacaaa tggcagccct ggatacagta atgcagtgag
     7201 taaaaaatca tgctgtatac accagaacag tccatacaaa aggcataaat accacagaaa
     7261 ccccttgacg ttttttgaca acagccagat attccttttg atcaaataaa caagactatc
     7321 tgctttatct tctttgcaga tatcaattag cgtactaaaa aaactatggg atacaaaaag
     7381 caacagacac aatagaaaag gaatcagata ccaagctcca atctttccca ctaataaata
     7441 ccaatcaact gcaaaaataa tgacaaacag ctgaaacaac gtaatgatga aacacatccg
     7501 tttgattttt cctttcctcc aacatacctt tttttctgcc aagtaatgga cagatagata
     7561 ataagaagga tacatcatca aaaaataaat cagatagaca acacgagcag acagcactaa
     7621 tcctaaagtg aacaaacatc ctagaactaa agcgaaaaga gcattactga taagactggt
     7681 taaaaaaatc cgacagacat agtagttgag cttgtaaaga aacatctctt ctattggctt
     7741 tttcatattc agcccttcag accgcttgta ctgatcccct ggacaagata tttattgaag
     7801 aataagaaaa tcagaaaaac cggtagcagc gacaacgtag acatcgcaaa catactcgcg
     7861 taagtcgtac tagatccagc gtctgcaaat aatttgatgg caatcgatac cgtgtaagat
     7921 ctcggcttgt ttaaataaat caatggtccc atgaagtcgt cccatttcca ataaaactgg
     7981 atgatgatcg tcgtgatgat cgaaggtttc agcaaaggaa aaataatttt ggtaaagaca
     8041 ctatacttgc tgcatccgtc aataatcgct gattcatcta actctttggg gatgctgacc
     8101 atgaattgca tgatctggta aatgaaaaat gcttgtccaa aaaaatgtgg taaaatcagc
     8161 ggcacatacg tcccaaccaa attcagccga ttgtaaataa taaactgcgg aatcaaaatc
     8221 acttgtgcag gaatcatcat cgttactaac atgacgacga accagaatct ttttcctttg
     8281 aaatcgattc tcgataatgc gtaagcaata caagtcgagc tcagaactgt ccctatcgtc
     8341 gaaactgcag agatgacaaa cgaattccta aagaaagtaa aaaatgaaat tccagcaaac
     8401 cccgcccatc cttttgcgta attttcccat tgaaaagtct ctggaatcaa attcagcgaa
     8461 ccactcataa tctcttgatc cgttttaaaa gaacctgcga tcatccataa gaccggataa
     8521 atcatgacta gacctaatag caaaataaaa ccgtattgaa accatttcgt tactgtatta
     8581 ttcatttctt cctcctctca ttcacacaac gacccatttt tttgatgatt tgaaaatcag
     8641 aaaggtgaca gctcccataa tcaacagcat gatccacgaa atagcactag cataccccat
     8701 agaattaaaa gaaaaagctt ggttatacac ataaagagca taaaagttcg tggcatcatt
     8761 cggaccacct tgggtaatga taaatgcctg cgtaaaagtc ataaacgccg cgattgtctg
     8821 cataaccaag ttatacaaaa tgatcggcga aagaagaggt aacgtgatct tgtaaaacgt
     8881 ctgccatttg ttcgctccat cgatctctgc cgcttcataa tacgagcctg ggatctcttt
     8941 gatacctgca gcaaagatga tcattgccga accgaattgc caagcagaca tcaaaacaag
     9001 agggatcatg accagttttt gatcgctaaa ccaggaaagc gcaggtgcgc ctaatcgttc
     9061 caggaaaata ttcactaacc cgtttttaga aaacaactcc cgccaaacta gagcgataga
     9121 aatactgcca ccgatcaaac taggcacata atacaaagaa cgaaagaaag tcgttccttt
     9181 gatattcctc gttaaaagat aagcaatcaa tagaccaaag atcagtttca caggtacaga
     9241 tgcaaataca tagagaaaag tgactcggat ggagttcaaa aaacgggcat cactcagcat
     9301 ctttatataa ttatccaagc cgatccatga gactggattt cccaaacgat aatcggtgaa
     9361 cgaataataa agtgacaaga tcatcggtat cactgttatc aatagaaatc ctaggatgaa
     9421 tggagaagca aatacgtaac cgaccacatt gtcttgatcc aagaaccgtt ttagtttttc
     9481 ttttttcatg ccttcctcct gctgctatcc tagaatgttt gacgcaaact cataaagact
     9541 ctctgctgct tcttctgctg ttacttcttc ataaatgact ttttcaacta aaagattgta
     9601 ttggtcttga atttccggat tcaaagcact atcaaagaca ttcacttcgc cgttgtccat
     9661 atcggaaatc atttctaaat aatcaaatgt cgcttgcaaa gttgcatcat ctgcacgagc
     9721 gagctgttct cgaatattcg acatgattgg tacaccacgt tctcctttta aaatttcatt
     9781 ggcttcttca ctgttttgaa agaaatcaat aaacttagca gcttcttctt tatgggctga
     9841 gctttttgcc atactcagca tttgcgaaga acgtaaaggg ataccagatt ctccatctgc
     9901 ttttctgcga ggtggattaa tcaactgaat ctccatatct tcaggagccc ctgacaatat
     9961 ttctgtcaac tggttacttg atagaaacac cattgccgct tctctatccc taaccgcctg
    10021 aaaagacaga tccgtcgtac ttgcagctcc accacctggt tctggatggg cccctttgtc
    10081 taccagattt ttacgcagct ggaaaaaatc tgttagatag tctggatttt caaatcccaa
    10141 gctgttagat agatcttccc gattataaaa attcaatcct ttctcaactt gtggtatttg
    10201 aataatacag ccagctataa aatcttcgaa tcttgaaata gcatagattc ctaattcttc
    10261 agtgatttga tagctgattt gttcaaattc atcccatgtc caatttgaag ctggttcagg
    10321 gatatttaat tgttcaaata tatttttatt gtaagcaatc gcaaacgaat tcaccccgtt
    10381 agacagtcca actaattgcc cgtcgtaagt cgtcgttgct aaataggatt catctgcatt
    10441 agaaatatca attatccctt gctccacata ttcatctaat ggttcaatct gattgatgta
    10501 ttgaggaaat tgattgttca gttggaaaat gtcccagata tcatctgatg ctgctagtgt
    10561 acctaatttt gtgtaatatc cttcataatc ataaaattca taatcgatcg tcacatgggg
    10621 atttttttct tcataaagct cgattacttt tactgttgca tcgtgtcgga cttgcgaacc
    10681 ccaccaagcc atgttcagcg tgattttttt gtcatcttct tgcccacaag ccgtcaagaa
    10741 gaataacata acacttaaag ctaagatgat tctcattctt ttcttcattc tctgcacctc
    10801 tacttccatt gttatttttc aatatactgt atttttatac agaacatatt tattaaacga
    10861 tctttttcaa ggggaataaa aaccaagact tgccttatcg ttctgcctag gatgaacaac
    10921 tcaatacttt caagaaaaat tagatagtgc tgattcttct ttcatcgcta aaaacacttc
    10981 ttgcttcaat gatgggagga taattacgca aagaaaaaag gatatcagac aactgcccaa
    11041 tatccttgac atagctaaat aagcatgctt cttcgtgtgc gctcttccct aaaaaacaga
    11101 aaaataacta gtaattctgt atgaaattag gtacaatata cacgtcgatg cacaagcatt
    11161 gactatggca acttgattgg tcagttcccg ctgacttttc aagccccgac aatttagctg
    11221 ctactaaatt gtcgggtgcc ttttttagtt tttattcgtt tttcattcta tagaaagcgc
    11281 ttcaataaat caagacattt ttttgttaga atgctaataa taacaaaagg ttttaactct
    11341 tcttatgtac attacaggta aaaaaacaaa aaaatttctc ttttttttga attctgaaca
    11401 aatagtactg gagtacaaaa gacgaggaag agccactatc tgctcttcct cgtcttttga
    11461 ttctcacctg ttattcatga ttctttttct cagtttcccg atatttttcc attttacgac
    11521 taaaaagctc tccgctactt ggtggcgtat atgtgatggc atttgctcct gcttgaatgg
    11581 tctcagcaat actttcttcc gttggaccac ctgtcgcaat gataggaagt tcaggatatt
    11641 ttttacgaaa atggcgtact gcttctgcag tttctttacc tgcactgata ttgataatcg
    11701 aaataccagc tgctaacttt tcatctattt ctgtatattt cgacgttacc gtactgataa
    11761 ctggaatatc aactactcga caaacttctt ttactgtctc taaaggcgta ggaccgttca
    11821 aaacgacccc taacgaacct tgcgcttctg cgaacatgct catgtaggaa gaacgagcac
    11881 cttgtgtcaa accaccacct acaccggaga aaactggaat gtcagctgcc tcaataatgc
    11941 ttttagtaat cgctggatga ggtgtaaaag gatacacagc aattactgca ttcgcatttg
    12001 tattacgtat gatcgcaata tccgtagtaa agatgatcga acggatcaat tttccaaata
    12061 tcttgatccc gcttgcttct aaaatgattt ccggtactct tacgatatct tttctcaatt
    12121 ccgtcatgat ttctggcgta aattgttctg ccatcagcca cttctccttt gctatctccg
    12181 gtcatactga ttcaattgat acgtctcgat gacctggatg attttttgcg cataaccggg
    12241 gtctgtcgca taacctgcat cttgcaatgc ttgtgcggct tcctgatagt tggtggccgt
    12301 aatcactttt tcatacagcg caggattcca atctactcct tggacgaaca gttgtgtatg
    12361 gtcatccatg gactgttccc atgaatcata cactttgaag tctccttgga tagttatcca
    12421 ttcttcgtta acaaattcct ttgtttccag gcttactttc ttctgatccc cataagcctt
    12481 gatcccgaaa agattattgt atttgctagc caaggtactt tttccccaat ttgattctaa
    12541 tatagcttgt cctaaaatga tactaggaag cactccataa ccatcttgta gttcttgggc
    12601 atgcggaaca agccgttcaa taaattgctg atgggattgc gcttcatttt cttgctgatt
    12661 atcagtaaaa ggagaagaca gattcttcaa ggaaaaaaca aaggctaaga gtatcactgc
    12721 tacaccggca accactgctg gccaacggat attcttgcgc ttttgctttt tccacttttt
    12781 tttcgccatg atcaattcct acttttcatt taattcattc agatattctt ctagcgtcaa
    12841 ttggtgtttg gtgatatact cagcgttttc tttaccgaca taacgtaagt gccaaggttc
    12901 atatgtgatc ttagttatat cttcgtgtcc ttttggataa cgaacgataa atccatactg
    12961 cgcagcatta tctgcgatcc atttagctcc aggctgatct ccgtaacttg catccaatac
    13021 agtagaagga taactgttgt accagttttg atcgacgaca tcgactgcca gacctgtgtg
    13081 gtgttcgctg tatcctggct ccgtaatcgt ttctttagta atctttgtcg cctcctcttc
    13141 tgatacacct tgacgactca tcacatcttg gacattttgt tcgaaaactt gttgttggga
    13201 tgatacagac cggtaagctg agaccatcac taatggaaat ccagctgctt cagcagcctt
    13261 ggcaaatgct tcatattctg gagcaatgcg tttgtcgatc aagtatccgt tacttaatga
    13321 tgccaattga gtagactcat caatttcttt ttctaatttg tgatctggac caaccaaaac
    13381 tagcttccaa tcgtctgttt taacatctgg caattgtttg gacgtacgat cttttgtttc
    13441 tttgtccttt accttgctgc tggttgtttg actgttcttt tctttactag cagttgtttt
    13501 ggtgcttgtt cgttcgactg cttgattgcc ggcttgaaca tgcgaatcat catcgctaaa
    13561 aataacatag cccattgctg cgatcataat cacaactgct ccaaatccta aaaatttatt
    13621 cacttgaaaa atcctttcgt tgttcttcac gttccccatt cgcctcatga acgtaagttt
    13681 cttccagatt ttcattcacc caatcgagaa gttcgatttt ttctccttcg atctgttttt
    13741 gaacatctgc tggcagacga aaattcaaaa tatcatcata gccccattca tcatattgaa
    13801 tacttacttt caagtcaagg tatctaccag cctgctgatt atttttcaaa gggatcagct
    13861 cgacttttgc tgctttgctg ctaagccatt tttgcgcgat gcgtgttttg atttgcttgt
    13921 actctgcaac ggcaacgttt cgtttttcgg gaaaaataat cgtttgacgc aaaatctttt
    13981 gcgttagcat ccattcataa tcagtgaaaa gattttttac tttctgcatc gcttcagatg
    14041 gcagattttt ctcgccatct ttccattttt gccattgttc tggactgatc agcaagtatt
    14101 catctaaaaa atttttttca gtttcaaact gttctaataa tacactcata ataagatcaa
    14161 tatatacttg atgcacgttt atcccctcct tttaactatt ctacttaagt tttgatcaaa
    14221 aagcacctct taaatcgctg ctttcatttt ttttaatgtt tcaagtcctc tcctctttat
    14281 tcttcgtgat ttttgttata ataatagaca gacaagaaac tcaatccaac tatgaaggag
    14341 cgttttcaga tgaaaaaata tcaatgggga atcgttggtc ttggtaccat cgcacatgag
    14401 tttgccgaaa gcttcaatca agagacgagc gaactaacag cagttgcttc cagaacttca
    14461 gaaaaagcgg aaaacttcgc tcaccgttac aatattccaa aagcttacgg aagctatcaa
    14521 gaaatgttag acgatgctga aatcgacatc gtgtacattg ctgtaccaaa tagacagcat
    14581 atcgaccata tcttggcagc attggaagca ggcaaacacg ttctatgtga aaaagccatc
    14641 acgatgaata aaaaagaact ggctgacgct atgcgcttag cagaagaaaa gaatttgatc
    14701 ttagcagaag cgatgacaat cttcaacatg ccactttatc agcagttacg ctcaataatg
    14761 gatacaggaa aactgggggc tttaaaaatg atccaagcac ctttcggcag ttacaaagaa
    14821 ccagacccta aaaaccggtt cttcaatcca gaattagctg gaggagctct gttggatatc
    14881 ggtacgtatg ctgtatcttt cgctcgtttc tttttgagct ctcaacctga agtagttgcc
    14941 tctacaatgg ttccttttga aacaggcgtg gacgaacaat ccgtcactat cttgcgtaac
    15001 aaagaaaatg aacttgctgc tgtcagcttg acttttcagg caaaaatgcc aaaagtcggt
    15061 atcgttgcct ttgagaacgg ttatgtgacg attgctgatt acccgcgtgc tgatcgtgcg
    15121 gagatcttat ttacagatgg tacaaaggaa ttcatcgaaa gcgggaatac atctgaagca
    15181 atgaattacg aaataaagaa tatggtacac atgattgaag gtgacttgcc caatcgctct
    15241 ctcttcttga caaaagatgt catcgaaatc ttggatcaaa tgcaagttct atggaaaaat
    15301 atgtaatttt aaaaggttgt gaaaaagctg ttctgcatca agtaataaga acagccaaac
    15361 aaaaatagct cctcctattt ttcgtttggc tggacttatt accgcagagg aaagcttttg
    15421 aacaccgttt aagaaagagg ttgtgagcct accgttcagc tccgagtcac aaggagcaat
    15481 ttcaaaaaac agcttctcat gtttgttgaa tattgtgact tgtgaccgag gagttgacag
    15541 gagaacaccg tttaaagaag aggttgtgaa atcagctttt tgacctgaat attagctgaa
    15601 ttcacaacct ctatttttgg attttttgtt gggagaattc tgccttgatt tcaataaaac
    15661 ttttaaaaga ctgcaaaaac tggaacaatt ctgctcgatc ctcgaattca gggcgactag
    15721 tcggcagagg catttgccga tacaatacat aaacttcttc aatacgtgtt aaaatttgtc
    15781 tgccatcatt tgactctgaa aatgtttctg cagtataaat caataaacca tagatatgtt
    15841 ttccataata agctggttgc tggattctct ctagattttc cagcatgtct ttaatcacat
    15901 tggcctgtgc tcttctcata gagaagtaag tttcgtagta tagcggctgt ctgagccagt
    15961 agttttcttg atgttctctg gcatcttctt ggctttcgcg aatgaatgtc agtaaatgtt
    16021 cgcatttgat ctgcacatct tctttatttt ctgataaaag aaattctgcc atttgtctca
    16081 aaatatttcg aaattctttt tcgatctgta tttggttttc cttcagctgc ttcgtacgat
    16141 ctggcatgta aacatttgca agcaaagcaa atactaatcc aatcgccatt aatcccgctt
    16201 cattgccgat cagctgccaa gacatgtttt cctccactaa ataatgagtg accaaaaccg
    16261 aatttactac tatcccttcg gttaatttga agcgagaggc aagcgggatg aacaggaata
    16321 aaaaaagact gaagccaaaa atagtatacc caacagcaaa aaaactgaac agtgctgttg
    16381 ccgtagctaa tataaaggct gcgattcgat tcatgcccgt acgcaatgta gagcgcttgg
    16441 tatttcctac acttaataat gcaatgatcc ctgcagctgg ccaatacaac agcgataagc
    16501 tacccgctgt gaccatcgaa aagaagacac tgatcactgt tttgactgtt cgcattccta
    16561 tacgcattta cttccccctt ttttatttta attatacttg aataatgaaa aactagctat
    16621 cagacaaaag tttaggtatg atagtaaaaa gaccaaaaag gagaatctct atgcaatttg
    16681 gccgttttcg actaggtatg cgtacgatca aaagtgcctt agctgttttt ttatgtatct
    16741 tgttttttca tttgactcaa cgaggaatcc cgatgattgc tgcattatct gctgtttttt
    16801 ctttgcgtca ggacttgact acaaccgttt cttttggaaa gtctaggatc atcggcaata
    16861 cattaggtgg tacattagct atcatttatt tttttgtcaa aagctatttt cacaatgatt
    16921 ttttggtaga attgatcttg cttcctattc tagttattat tgtgatcgtc gtgtcagatg
    16981 gtattaacaa taattccggt atcatttccg caatagctac gttgttgctg attgcgttga
    17041 gcatccctca aggcgaatcc gctttgtatg ctatccaacg tgtactagat acttttatag
    17101 ggacattcat tgcaatcggt atcaatttct ttcttcgtcc tcctgaaaca gaaaagaagg
    17161 aagaactatc agaagatttg gtcgaactcc aaaagaaaga acgattgcta agaacaaatt
    17221 tacaagagat agaagctaag atccaaaaac aaaagaaaaa tagcgaggac taattttctt
    17281 ttgcaataaa ataaaaaaat ggagagaaga actttaaaaa gtcttcctcc atttttgatt
    17341 gaacggtgaa gtgtactact ttattcttcc ttcatcgagt tttgttctgc ctcttttggc
    17401 gcttcataca tatttacttg gctagtagtc ccacgtgtcg acaaattctc tacgatttcc
    17461 ttcaagtcaa gtcctgttgt cgcttttagt gtttcttgag tagaagaaag caaatttgtg
    17521 gcataatttg tcactcggtt cgctccactg gtttctcctg aactgcttcc tgtatcgaca
    17581 acagagattt tttcgatatt tcctagcggc tgtgctgctt cgcgcatcaa ttgcggtagc
    17641 atatcgataa ccatactcaa gacagctgct tcgccatatt ccttgaaggc attggcgatc
    17701 ttttgttttg cttcggcttc tgcttttcct tttgctagtg ctgcttcggc ttctgcttgt
    17761 ccagctaaac gtgtcttatt ggcttccgct tctgccagtg cttccacacg gaatcgttct
    17821 gcttcggctt cagtcacttc tttgactttt tgagcttgtg cttcttgttc tttagcgtac
    17881 cgatcggcat ctgctttttt cttcacttcc gaatcatatt gcttttcacg acgtgtgatt
    17941 tctttttctt ccagttcgat ttgtttttga cgttctacga ttttaatctg catttcctgt
    18001 tcgattactt gttgttgtgc tcgggcactt tctaaattgt aggcttggtc tgcttttgct
    18061 ttagcaacat cttgttcttg tttgtaggtt gctaatttca gttctttttc ttttaatgat
    18121 tctgcgatct ctgtttgtcg ctgtaattca gctgcttgtg attctttttc tgcttgagct
    18181 tttttgatac gcgtttcttt tagagcttcc gcttctgcta tatctgcatc tcttttgact
    18241 tgggcgattc ttggtttccc taaagagtca agataaccgt ttttgtctct gacctctttg
    18301 atagtgaaag aaacgatgat caaccccatt tttgcaaggt ctacagaagc gacttcttgt
    18361 acgctttgac tgaacttatc gcgattttga tagatttctt ctacagtcat agaaccaaga
    18421 atcgagcgca agtgtccttc taatacttct cttgcttcat tttccagttc ttctcttgtc
    18481 ttgcctaaaa actgttctgc tgctgtagca atctcttcta cagatgaacc gattttgatg
    18541 atcgaagtac catcacacat caccggtacg ccttgttccg tatacacttc aggggtggag
    18601 acgtccaatt tactcgataa tagactgatc cgattcgaac gttgaaaaac tggcaagacg
    18661 aatgcgccac ctccacgcac aattttgatt ttgttattgc tttcatcaat gtgcacattt
    18721 ttgcttccta aataacttcc actgatgatc aacgcttcat ccggttttgc tgtctggtac
    18781 ttcgctacaa agacgatcag caacatcagt aaaatcaaag ctgcgattgc gatcgcgata
    18841 aaaacaactg gtatttccat ttaacacacg ctcctttaag cttttatcat gctttcataa
    18901 ggcatgacat aacagattct ttccttgatc tcaatgatca atactttcgt tccccgctca
    18961 gctgtctgtt cttgggggct gtaaaaacaa gctggacgac taatggaacc ggtaacactt
    19021 ttcaactgaa tttctcccat acctcgtaca gggatcggtg tgatcacaac agctacttgt
    19081 ccttccagag ttttttcaga agacgacatc gttgattcgg catgtttcat cggcatcaat
    19141 atatagaaat taagcaaaaa taccaacact atcgatatgc ctccactagc aataaataaa
    19201 aataaagatg attgatctgt taaacgctca cctagaaaac caaataagct tgtgaaagtt
    19261 aaccaaggga taataagcat cggatcaagc gggccatcaa aatcgaatac atctccaaaa
    19321 ataatcaata ggactgccaa tcctgcacaa atcagcaatg tataccaata aatcgtctca
    19381 agtgcgattc cccctatcat atacacgcct ccttccattt ctacgtctat cataccaatg
    19441 tttgaaaatt ctgtatagct tcttttaccg actcagtggt gttttttata ggaaggttgt
    19501 gtttatcgtt gacaatttgt taaatttttg ttttcatgtt aaaattttca caataaattc
    19561 tttcgaggta gcctatgttt ccttttttta agaaaaaacc attaaagctc cagaacacga
    19621 tcatccttgt cgtttgtttc tccacattcg tttctttgat tgtttctgcc atattgatca
    19681 ggaattttat tctttcgatg aaccgatcta gtgtgtcaga taaaatctct agcattgcta
    19741 aaatcgttgc caatgataaa ctcatccaaa aaaagctgca gactggtgac ccgacacatg
    19801 cgattcaagg aataacaaat gaaatcatga ttgcatcgaa tttagatttt atcgttgtca
    19861 tggaccctga aggcattcga tattctcacg cagacccaag ttacatcggt cttcctttct
    19921 caagtcatga agatgtgaaa aaagtgattg gaggacaaga atttttctct gaaaaagaag
    19981 gaatgttagg gttcggcttc cgctatttcg tccctattta ttatgatcaa gagattattg
    20041 gtgcagtttg tgttggctta acaaacaaca cgattgacaa tcaagtcaaa gatggacaaa
    20101 aaatgattgt tttttcattg attattggac ttagcgtagg catcataggc gccgtttttc
    20161 ttgcccaaaa aatgaaaaaa gtactgcttg gacttgaacc acaagaaata gcagaacagt
    20221 taagtgaaaa aacgattatc gaaaatgaag tagatgaagg aatcttagcc atctcttctg
    20281 ataaaactat cctcttgatc aatacacctg caaaaaacat tttctaccaa acagagcagc
    20341 tattggattt cgaagtagga aaaaaatcag tgataatcta tatgacgttt tgtttaaaga
    20401 gacgattgag catcaaacga ccgttcggac tcaatccatg tatttaaatg ggatagaaac
    20461 tatttctagc gttacacctc tttttagcaa tgaccgtttt ttaggagcag tcgcaacttt
    20521 acgaaatcga tcagaagtaa tgaaattaat ggaggagctt ggggggacga aacaatatat
    20581 aaactccatg agagctcaaa cccatgaatt catgaataaa cttcatgtca tttctggttt
    20641 gattgatttg aagaagtatg aagaagtcac ccattttatc cagcagctaa atcaaaatta
    20701 taaaaaagag attggccaag tctcaagtct gatcaaagta cctgcaattg ccggtttttt
    20761 attaggcaaa ataaacgaag ccaaagaaca atctgttgaa atgctgttag aaagcgattc
    20821 ttttatccct aaaatggaga tggatgactc catccattca cttttgcaag tgttagggaa
    20881 cttacttgat aatgcaaaag aagccgtgct acaaaaacat gaaagaaacg gacaggtccg
    20941 gattcattta aactatgaca cagaagctga agtattcatc gtgaccgtct gcgatgacgg
    21001 tgtcgggata tcagaagaaa tctcagaaaa aatatttacg ctaggttttt cgacgaaggg
    21061 aatcaatcgt gggtttggat tgaatctcat ccattcaatc gtcaaacgcc acggtggatt
    21121 tttagaattt tccaaacaaa caaatggcgg tacaatcgtc tatctagaat taccaaaaaa
    21181 ggaagatcaa aatgatgaca aatgtcctga taatcgaaga tgatccaatg gttgcagaat
    21241 tgaatcgtac ttttgtggaa agcatcccta atatgaacgt aatcgaaagt ttcagaaatg
    21301 tagaagaagg aaaaaaatat ttcagacaaa aaaacgcaga tctgctgctg cttgatgtat
    21361 acatgcctgg cgaaagtggt atccattttt tatcttggct tagacagcaa ggaaatgata
    21421 tcccagtgat tttgatcact gctgcagatg atatcgaaac cataaagaat gtgatccgct
    21481 acggtgcctt agattatttg atcaaaccgt tcactttgca acgttttcag ctggcgatcg
    21541 aaaagtatct tgctttctct cagacaatcc aaacgactga aaaagccgat cagaaattga
    21601 tcgatcaagt attcaaccac accactccca ttcacgaaat accatcattc atcgatttgc
    21661 ctaaaggtct gtcaaaactg actttaaaaa aaataagtgc atttattcta aaagaagata
    21721 ctattttttc aacaaaagaa ctggctcaaa aaagctcact gtcacgtata tccgtcaaga
    21781 aatatttgaa ttttttagta gaacaagata tattgaacga aagaatcaaa tatttggaaa
    21841 tcggccggcc gctaacctgt tatgaattga caaagaatgg gcggaaaaag ctcacagatt
    21901 actgttgagt catcgaatta tcccatacaa aatagtccaa gtatacagaa gtaacaactg
    21961 tttacttgga ctatttttaa acattttatt gacgaatatc catgttttct tatcttaatt
    22021 gacgggcttt aggaagagat acctcatttt tcgtttttcc agtttctatt atttcacgaa
    22081 agttctcgaa acttgtcgaa atcatatttg ataatgcctc atctgtattt gaacctacat
    22141 gcggggttac aagaactcta gggtacattt ctactaattg ctggatagca gggtctggaa
    22201 tcgtctccca tggcttgaag gatcggaaaa aaacctctgt ttcatttgca aaaacatcgg
    22261 ttgcaaaacc agctaaatga ttgcttttca aagctcttaa aatagcttca ttatcttgaa
    22321 gctctccacg ggctgtatta atcaagatgc tacctttttt catttgagct aaaaatcctt
    22381 cattgatcat ttgatcgttt tcacctggga tatgaggtac atgaatactg acaatatcgc
    22441 ttttggctaa taactcttca agcgagtgga acgtcaatac ttttttagca gcttctgtct
    22501 gatgaatatc gtagccgatc actttggctc ctagtccctt aaacaaaaca gcttccgtca
    22561 accctatcct gcctgttcct atgatcccta ctgtgcaatt tctgatttca cgactaaaca
    22621 tttgctcatc cactcgaaaa tctttgaaag atgttcggat cgtcgtatac gcagtatttc
    22681 tcaaaagcat catggcaaaa gtcaaagata actctgctat cgcatttggc gaatacgatg
    22741 gtacacgggc tactgtcata ccaaaatcag ctgccgcttg tagatcgata tgattgactc
    22801 ccacagtccg tgtaaaaaca taacgaatcc catattcctg catttttgca agattggtct
    22861 catctgctat acaatttccc ctcaacaata cagcatcatg gtcctttgct gacacgatat
    22921 tgtcatgtgt caacagttct tcataaagac tgagatcata atggtaaata ttcaattttt
    22981 caaaaaaatc tatctcgttc ggacgaacac cgtaacatgc gattctcata ctttcttcct
    23041 ccatttctta tgaaaataaa cctatgccat gaatcatttg taatacaacg atccatacag
    23101 gtgtcagtac cacagcaaaa atagttgaca gtaaggatgc attggaggct aaaagtgcct
    23161 ccctatcaaa actgatagca taggctgctg ccactgttgc agctggtgta gccatcatga
    23221 taacgattgt tgccagtgct tcaaaattga ctggtagaat attcgttgcc gtcaaaactg
    23281 ctagaatcac gatattcaat gcaggtacaa ataccacttt gactagactg taataccatg
    23341 aagttttttc agatgcagct tttttgaagc ttacttcacc taatgttgcg ccgattgcta
    23401 gccacgccaa tggtgaactt aaaccagcta aataatccat cggctgaaat agccacggtg
    23461 cagtctggtc aattcgcaaa aacgctactt ggcttatctc tccttctgca cctgtaactg
    23521 acacttgtgg cagataccct tggaacagcc aaatgaaaag gccggcaaaa gtagcgataa
    23581 tgattggatt gacgaacatc gctttgatat ttttagcttc catcttcaag ccactcattt
    23641 ttatgtatcc ataagaatac aaaaagattc ggtagccaat attgaaaatt gaggaataca
    23701 tcacgccgac aggaccataa atcgcactga cgataggcgt tccgaaaaag gtcgtagaac
    23761 caaagatcgt caggacacgc aacgttgttt gcttatcccc tttatagctt aagaaaaaag
    23821 gttttgaaac tagaataaga ataatataaa taactaatcc ccaaatcaag acattgattc
    23881 cttgcatcag taattctgta ttgatatctt gcatgaaagc tcgaaatgcc agtgctggca
    23941 aagccactgt taagacgact ttcgatagaa tttttccaac agattcagaa aaaatcccct
    24001 tttttctaca aacaaaccct aataatataa taaaaactgt tgaagtgatt gcactgacaa
    24061 tcgacatatc tgtcaaagtc gatcgaaaaa tgtcaaataa gttcatcttt ctcctcctaa
    24121 ttatgttcat ttattcacaa taaaaaaagc ttttattttg ctaatacgta ttaacatttt
    24181 taattttatc tttacattgt tacttattga acaataggaa attaaagaaa cttttgaaac
    24241 ttatgtaaag tgatt
//
LOCUS       DADGHT010000038        23654 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.038, whole genome shotgun sequence.
ACCESSION   DADGHT010000038 DADGHT010000000
VERSION     DADGHT010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.038"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(27..602)
                     /locus_tag="JX887_001367"
     CDS             complement(27..602)
                     /locus_tag="JX887_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAX1257366.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(607..1581)
                     /locus_tag="JX887_001368"
     CDS             complement(607..1581)
                     /locus_tag="JX887_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HAX1257367.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1605..1649)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1864..2832
                     /locus_tag="JX887_001369"
     CDS             1864..2832
                     /locus_tag="JX887_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1257368.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2929..3222
                     /locus_tag="JX887_001370"
     CDS             2929..3222
                     /locus_tag="JX887_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAX1257369.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3340..3576
                     /gene="secG"
                     /locus_tag="JX887_001371"
     CDS             3340..3576
                     /gene="secG"
                     /locus_tag="JX887_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAX1257370.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3688..4434
                     /locus_tag="JX887_001372"
     CDS             3688..4434
                     /locus_tag="JX887_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAX1257371.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSLAEQ
                     QLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4437..6794
                     /gene="rnr"
                     /locus_tag="JX887_001373"
     CDS             4437..6794
                     /gene="rnr"
                     /locus_tag="JX887_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAX1257372.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6816..7280
                     /gene="smpB"
                     /locus_tag="JX887_001374"
     CDS             6816..7280
                     /gene="smpB"
                     /locus_tag="JX887_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAX1257373.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7582..8301
                     /gene="atpB"
                     /locus_tag="JX887_001375"
     CDS             7582..8301
                     /gene="atpB"
                     /locus_tag="JX887_001375"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAX1257374.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8354..8569
                     /gene="atpE"
                     /locus_tag="JX887_001376"
     CDS             8354..8569
                     /gene="atpE"
                     /locus_tag="JX887_001376"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAX1257375.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8660..9184
                     /gene="atpF"
                     /locus_tag="JX887_001377"
     CDS             8660..9184
                     /gene="atpF"
                     /locus_tag="JX887_001377"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAX1257376.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9171..9713
                     /locus_tag="JX887_001378"
     CDS             9171..9713
                     /locus_tag="JX887_001378"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAX1257377.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9736..11292
                     /locus_tag="JX887_001379"
     CDS             9736..11292
                     /locus_tag="JX887_001379"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAX1257378.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11306..12208
                     /locus_tag="JX887_001380"
     CDS             11306..12208
                     /locus_tag="JX887_001380"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAX1257379.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12231..13637
                     /gene="atpD"
                     /locus_tag="JX887_001381"
     CDS             12231..13637
                     /gene="atpD"
                     /locus_tag="JX887_001381"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAX1257380.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13651..14073
                     /locus_tag="JX887_001382"
     CDS             13651..14073
                     /locus_tag="JX887_001382"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAX1257381.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14542..14772
                     /locus_tag="JX887_001383"
     CDS             14542..14772
                     /locus_tag="JX887_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAX1257382.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14869..16170
                     /gene="murA"
                     /locus_tag="JX887_001384"
     CDS             14869..16170
                     /gene="murA"
                     /locus_tag="JX887_001384"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAX1257383.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16183..16359
                     /locus_tag="JX887_001385"
     CDS             16183..16359
                     /locus_tag="JX887_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAX1257384.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16494..16790
                     /gene="yidD"
                     /locus_tag="JX887_001386"
     CDS             16494..16790
                     /gene="yidD"
                     /locus_tag="JX887_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAX1257385.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16854..17321
                     /locus_tag="JX887_001387"
     CDS             16854..17321
                     /locus_tag="JX887_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1257386.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17406..18290
                     /locus_tag="JX887_001388"
     CDS             17406..18290
                     /locus_tag="JX887_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1257387.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18407..18640
                     /locus_tag="JX887_001389"
     CDS             18407..18640
                     /locus_tag="JX887_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAX1257388.1"
                     /translation="MSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18728..18808
                     /locus_tag="JX887_001390"
     tRNA            18728..18808
                     /locus_tag="JX887_001390"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18762..18764,aa:Tyr,seq:gta)
     gene            18815..18886
                     /locus_tag="JX887_001391"
     tRNA            18815..18886
                     /locus_tag="JX887_001391"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18847..18849,aa:Gln,seq:ttg)
     gene            19402..20109
                     /locus_tag="JX887_001392"
     CDS             19402..20109
                     /locus_tag="JX887_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1257389.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20168..20812)
                     /locus_tag="JX887_001393"
     CDS             complement(20168..20812)
                     /locus_tag="JX887_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAX1257390.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            20939..21226
                     /locus_tag="JX887_001394"
     CDS             20939..21226
                     /locus_tag="JX887_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257391.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21334..21654
                     /locus_tag="JX887_001395"
     CDS             21334..21654
                     /locus_tag="JX887_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1257392.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            21972..23048
                     /locus_tag="JX887_001396"
     CDS             21972..23048
                     /locus_tag="JX887_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAX1257393.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            23045..23654
                     /locus_tag="JX887_001397"
                     /pseudo
     CDS             23045..23654
                     /locus_tag="JX887_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
BASE COUNT         7820 a         4125 c         5092 g         6617 t
ORIGIN      
        1 tattttgcta atccagctct gtttattcag cctatttttc tttttgaata tatcaagcgt
       61 tgtggcaaca tagtgatgac taatgaaaca acgacgatag acaacaaacg atcaaggtag
      121 tctgtacctg cctgtaccaa gatcacactt gttgtctgac ttaaacctaa cccatgtaat
      181 agctgaacga tcatactgga tcctgaggag gtgatcccgc caaataactg aacggtaatg
      241 atcgaagaaa cgatcgttcc aggtaccgac aaaatcaaag cgagtaataa cagtttcaag
      301 ctgtttttat ctttgccgag atatcttggc aaaatcaatc cagcaagcaa gcctgtgaga
      361 atttggattg gcgaataata cagagaaaaa atatctgtag tcactccact taaaataccg
      421 ctggacaatc ctgtcagcat tccaggtaca ggcccaagca atgcaccagc aaaaatcgtt
      481 ccgatagaat cgagatagat tggcaaacga agccataaag caatcgttcc tccaatataa
      541 ttgatcccaa tacacaaagc catcactgta agtacgcgag ttgccatttt gtttttattc
      601 attttgttag cccatcttta acctttccaa atctttcata atcgtttctt cttgtgcatt
      661 taaaagaacg gttaaaaact ttcggaaaaa aagacgagta tctacttttg tcataatttt
      721 actgttagca ggtttctgcc aaaattcata acgatcaacc aatgtttgtc cacgacttat
      781 tccttgagtt tccacagcag tgaagctttt gaaaccttca cagatggcct cctcgataaa
      841 ataagcaaca gctaacggat cattgatgac acatcctaaa attctttctt gtttccagtg
      901 gaagtcaaaa taaaaacgag tgatcgcttt tagatactct ccctcttcag gattcatttg
      961 acagcagtat tcgaggatag tcggtgtcaa gacgatttct cttgtcacat ctaacccaac
     1021 catttctatc gtttgtttga gattctcgaa tacataagaa gctgcttcag gatcacacca
     1081 gtaattgtat tcagcaactg gcgaacagtt accatggctt ttgtaagttc cacccatcga
     1141 gacaaaacgt tccatatgtt tcccaatatt tgggttgact ttcaaagcag aagcgatatt
     1201 ggtcaaagga cccaaagcaa tgactgatgt atttgtcttt tctttgaaat aatcagccaa
     1261 aaaatcaacg gcatggagag gttctgcctg ttttctcaag atcatcggga aatttgtttc
     1321 ccctaaacca tccataccat gagtgtcttg tgcactgatg aaaggttgct tcaaaggttt
     1381 ttccattcct tgataaacag gaatgtctaa acgatcacag cgttccaggc atttcagcac
     1441 attctgcgta cctatatctg cagggacatt cccacaaact acggtaatag caactacttc
     1501 gatatcaggg gatttgacag ctaatgataa agctaaagtg tcgtcgatcc ctggatcgca
     1561 atcaataatt acttttcgca ttatttccaa tctcctttct ttagagatac ttagtttttt
     1621 attctgggaa gtttccgaac cagtccaaga cgagcgtctt gattataatg cacgaaatta
     1681 gtatactggc ttttattgcg aatgtaaatg ctctcttaca agtaaatcta ttgaggagaa
     1741 ctttaagtaa atgatacaat gaaaaagaaa tggaatttac gtgtgccgaa aataaagaat
     1801 cctatggatc ggtacattgg ataatagata gattatagtt tggcagaaag cggcgggtgt
     1861 acaatggtta ttttttattt cattcttatt ctgataatta tagggatcag ttaccatttt
     1921 ctttcttatt tttatgcaaa gaaattagta agagcgggag tacagagagg atatgactgg
     1981 tatgaagaca ctggtcatcg tttgatggac cctgctgcag tcacgtcagt agaaaaaaaa
     2041 cgacaaaaat tagaagaaga gtgtgaaagc ttttgggagc agggaacacc caaaacaatc
     2101 aaaagttatg acgggttgaa actagctggt cagatgttca tccatccaaa taagcagaat
     2161 aaatgggtca tttgcgtaca tgattaccga agcacaggga aaagagacat gtctcatata
     2221 ggtaaaagat atgcagagaa aggattcaac gttcttgtac ctgatttacg tgcgcacgga
     2281 gaaagtgaag gagaaatcat cggaatggga tggctagatc ggctagattt aattgcctgg
     2341 atccaactca tcttagatga acagccgaat gcgtccatta ttttacacgg cggatcaatg
     2401 ggagcttcta cgatcatgat ggcaagtggt gaaaaacttc catcagcggt caaaggattt
     2461 attttagaca gcggatatgt ttctgtttat gcagaattcc gatatatgtt aagtaaaatc
     2521 actgtctttc ctaaaaaaat ggtcatgaga tatgcgaatc attatgccca gaaatacgcc
     2581 ggttactcct taaagcaagc atcagctacg agacagcttg gcagcaatca tctgccttta
     2641 ttagtcatcc atggtgaaag agatcatttt gtccctacag aagcagcgta cacgattcaa
     2701 aatgctacgg caggggataa agcactgctg cttgttccgg aagcagaaca cttggaagca
     2761 tcgatgaaag atccgaaaac ctattggaca gtgatttttt catttattga acaaagaata
     2821 acgatgaatt aattttctct tcttttttgt aagtaattcg aggataaata attgtttata
     2881 gatcaggaga ctgctaaaat aaggtaggaa taaaaaaata tcagttattt gaggagtgcg
     2941 gcatatggaa atcaaagaag aaaaaatcgt cttgctttat tcaatgatga acaacaagag
     3001 atcggagaaa tgacatggtc agatgcgggc ccagacatca tgatcgttga ccatacattt
     3061 gtagatccag catatcgtgg tcaaaagtta gctgaaaagc tagtgtatac tggagtagaa
     3121 ttagcaagac gagacgggaa aaagatcatt cctttatgcc cttatgcaaa aaaagagttt
     3181 gaaaagaaac cagaatatca agacgtctta cgtcagtcat aagaataaca gctgaaagtt
     3241 ttgaactttc agctgttatt ccatttatat agagttgtca cggactttta tctatgataa
     3301 agttaaagag acgatatctt ttgggaagga ggctgcgata tgtataattt aattttggga
     3361 atcgtgatcg ttttatcgat tgttatggtc attgcgatta tgatgcagcc aagcaagcaa
     3421 aatagtgcag cgagtgcatt taccggcggt gcggatcaac tattcggcaa acaaaaagct
     3481 cgcggctttg aagctgtcat gcagcgatca actgcagtta tgggagctat ctggatgatc
     3541 ttattatttg tcctagcata tttatcttcg aagtagttga ataagcctct cgcaaaacgg
     3601 cgggcggctt tttttattgc aaagagaacg cttaagaaga agttatgaaa gaaactatgg
     3661 taaaatgagg cgaaagaggt gagacgagtg agacaattac caaaacccct ttatgcaaaa
     3721 catggaaagc gagcggtttt gctgcttcac gcttactcag gaagtccaaa cgatgttcga
     3781 atgctcgcac gatttttgga aaaagcagat tatacagttt atgcgccgct ttttaaagga
     3841 cacggaacaa tggagccata tgatatcttg caagaaaaag cagaaagctg gtgggcagac
     3901 actaaaaaag ccatccattt tttacagtct gagcagtttt ctgatattgc cgtattagga
     3961 ttatcaatgg gcggcatctt tgctgtacga gcactagaag aagaatcagt gattggcggc
     4021 ggttttttct gttcgccttt gtctcctgta aaaacaaacg tgcctgaaaa ctttgaaaaa
     4081 tacgtacgtc aagtgctgaa gacagcaggt aaatcagaga aagaaatcaa tgaaaaagca
     4141 gttgcttacc gctcgttagc tgaacaacaa ttaatggata tacaagatca ggcagcaatc
     4201 gtagaaagta ggttgtcaga tatccaacag ccgatatttt tagctcaagc tgggaaagat
     4261 gaaatgatcg accctaatgg cgtatttgaa actgcacgca agttgagccg tcagcgagtg
     4321 acacttcaat ggtatcctga aagtggtcat gtgattacag ttggtacagc aagacgcgaa
     4381 ttagaaaaag acgtcttgga atttttagaa aaattacctt ggaatgagga ataaatatga
     4441 caaaagaaac gataaaagag aaaattctct ttttcatgga aagcagtcgc aaacgcagtt
     4501 tttctatgga agaaatcgct gaaggtttag ggttccaaaa aagcgatgat tttaaattac
     4561 tagtacaaac gattgctcaa atggaaagag aacagagtat agttttcaat aaaaaaggaa
     4621 aagtgaaact tcctttaaaa ccaatcctga tcgaaggaac atttcgagca aatgaacgag
     4681 gatttggatt tgtaacgatt gatcccgaag aagatgacat ctatatccca aaagaagcga
     4741 ctggttttgc aatggatgga gacaccgtag caatcgatat catgaagcga gcaaatacag
     4801 atatggatcg cggagcagag gggaaagtag tcgagattcg agaccgggcg actactcagt
     4861 tagcagggga attcgttgct tattcagaag aagaaataca agaaacagat ctttacggcg
     4921 ttgttatccc gaaagataga aagctcaacc aatttaaagt atatgcagca gcagagggag
     4981 ttcgtccagt tgacggaagt attgtgctga tcgaactgac ccattaccct gaaaaagggt
     5041 atgcgactag tttagaaggg ataatcaagc aagtgattgg tcataagaat gaccctggca
     5101 tggatatcct ctcaattgtc gtggctaatg gtatccctac gaaatttcct gatgatgtat
     5161 tgtctgaagc agatgaagtt ccagatcaaa tcagcgaaaa ggatataact ggacgtagag
     5221 atttaagaaa tcagctcatt gttacgattg atggagaaga tgcaaaagat ctagatgatg
     5281 cagttacggt taaaaaatta gataacggta attattttct tggagtacac attgcagatg
     5341 tttcttacta tgtgacacaa ggcagtcaat tggacagaga agcatatgaa agagggacaa
     5401 gtgtatattt gactgatcga gtaattccga tgatcccgca acgtttatcg aatggtatct
     5461 gttcactgaa tccccatgtt ccaaggctga ccatgagttg cgaaatggag attgatccaa
     5521 atggacaagt agtctctcat gatattttcc caagtgtgat ccaaacaaca gaacggatga
     5581 cctacacagc tgtcaatcaa atcttagaag atcaagacga agaaacgatg caacgctatg
     5641 ctcagctcgt acctatgttc caagaaatgg gtgaattgca ccgaatcctt gaaacgatgc
     5701 gaatcaaacg tggcgcgatt tcttttgagg atcgcgaagc gaaaatcctt gttgatgctg
     5761 aaggacaccc aaatgacatc cagctaagaa gcagaggaat tggtgaacgc ttgatcgaat
     5821 ctttcatgct tgcggccaat gaaacggtag ctgaacatta taataaatta aatctgccgt
     5881 ttatttaccg aatccatgaa cagccaaaag aagaaaaaat gcagcgcttc tttgattttg
     5941 cttcagcttt gggcattctg gtccgaggaa cgaaaggaac gatcacacca aaagatttac
     6001 agcatgtgat cgaaggagta gaagacaaac cagaagctgc agttatcaat actatgttgc
     6061 taagaagcat gcaacaagca cgctattcag aagacaattt tgggcattat ggcttagcgg
     6121 cagattacta cacacacttt acatctccta ttcgacgcta tcccgatcta atcgtccatc
     6181 gtctgatccg ttcttacagt gaagataaaa gtgaaagcaa tcaaagttcg tgggctgcgg
     6241 aacttcctga aattgcagat catagttcta agatggaacg tcgtgcagta gaaacagaac
     6301 gtgaagtaga ttccatgaag aaagcagaat tcatgatgga caaagtggga gaagaattcg
     6361 atgggatcat cagctctgtt gtgaaattcg gcctgtttat cgaactgccg aatacagtag
     6421 agggattgat ccatatcaat gaattgaaac aggactactt ccattttgtt gaaaatcatt
     6481 tagctcttgt aggtgaaaga actggtctga cttttaaaat cggacagaaa gtgcgagtaa
     6541 aagtagtcaa agctgatcca gatgaacgag cagtagattt tgaacttgtt tccgcagaag
     6601 aggttacagc gttggaacgg ccaaaaacac gaaatggaaa atcaggaaaa cgcgaaggaa
     6661 aacaagcagg aaaacgccca gaaagaaatg gcaagaagaa caaacgatat agcgatagta
     6721 agcaaacgtt cggtaagaaa aaagggaaga agccatttta caaaggtgtt aaaaagaaga
     6781 aaaagaaaaa ataaaatgag ttggaggaaa cagctatgcc aaaaggcgag ggaaaattaa
     6841 ttgcacaaaa caagaaagct cgccatgatt attcgatcat cgacacgatg gaagcaggga
     6901 tggtcttgca aggaaccgag atcaagtcga tacgaaacag ccggatcaat ctaaaagatg
     6961 gatttattcg cgtccgcaac ggagaagctt tcttgcataa tgttcatatc agtccttatg
     7021 aacaaggaaa tatttttaat catgatccgt tgcgcacgag aaagttatta ttacacaaaa
     7081 aacaaatcat ccggcttgaa aatgaattga aaaatactgg aatcactgtt gttcctttaa
     7141 aagtctatat tcgtaacggc tatgccaagg tattgattgg tctggcgaaa gggaaaaaat
     7201 cttatgataa acgggaagat ttgaaacgaa aagatatcga tcgacaaatt gatcgaacat
     7261 taaaaaattt ctctagataa tttcattatc ctttttcgca tattcggtgc ttttgctttt
     7321 acttaatgat aaaatttgtt agcatttaat ctgataaaac atgattatca taggtttttt
     7381 cttagatcag gagcaccgtg tataaagaaa aattcgcttc gtttttgact gaaataaaaa
     7441 agtgtctaat tttcatgaaa atgttttgaa ttttctgttt catggtggta tgataccgtg
     7501 tggttagaaa ccgattggaa aaaaccagat acgcacatga attgatttta tgtgaatttc
     7561 ggggaaaaga ggtgaaatgg attggatgaa cgctcgctaa cgttccacat tggaccaatt
     7621 tggtttgatg gtacagtttg tataatggtg ttactgacct gtttgattgt tttcttctta
     7681 gcttactttt ttacaagaaa tcttaagttg aaaccaacag gcaaacaaaa tgcgatagaa
     7741 tgggtcattg attttagtcg aggaatcgta acagataatc tgcctagaaa agaattgagc
     7801 aatttccatt tgttggcatt tacattgttt ttatttgttt ttgttgcaaa caacatcggt
     7861 ttagtaacaa aaatcgtttt acctaacgaa acaacacttt ggaaaagccc gacagcagac
     7921 ccgtttgtta ctttaacttt ggcatttata atgatcttac ttactcactt attcggggtg
     7981 aaaaagttag gcttcaaagg atatttcgta aattcgttct tgaaacccta tagttttatg
     8041 tttccgatga aactgattga agaatttaca aacttattaa cacttgcttt acgtctttat
     8101 gggaatattt atgcggggga agttttgcta accttgattg caaaaatgat gacaagctta
     8161 ggctggttct cattaccatt agcaattcca ttagagatgg tctggatcgc gttctccttg
     8221 tttattggga gcatccaagc atttgtcttt gtcactttgt caatggttta tatgagccat
     8281 aagattgaag tagaagaata atactcggtt aaaaaacaaa ctactattta tctattttag
     8341 gaggaaaaca attatgaatt atatcgcagc agcaatcgca atcatgggag cagcaatcgg
     8401 agccggttat ggtaacggtc aagttatctc taaaacaatc gaatcaatgg ctcgccaacc
     8461 tgaaatgtct ggtcaattcc gtacaacaat gtttatcggg gtagctctag ttgaagctgt
     8521 tcctatctta ggggtagtta tcgccttgat tctagttttt gccgtttaat tgaatcagta
     8581 ttaaggcaga aacaacatcg tttgttactg cttttttaca tggaaactag aaatactcca
     8641 aagaaaggaa ggctcgccta tgctgaatca attggcaatt gcagaagttg gcaatgcgat
     8701 gttaggtaat atcatcgttg tcagcggctc atttttgata ctactggctc tcttgaagca
     8761 ctttgcttgg ggaccaatca gcgatatttt gaaaaaacgt gaagacaaga tcgccaatga
     8821 tttagattct gcagaacaat ctcgcatcaa ctcagcgaaa atggaacaag aacgcgaaca
     8881 acaattgtta gcctctcgtt ctgatgcagc tgatatcatc aaaaatgcga aagaaagtgg
     8941 agaattaagc cgccaaaata ttttgaagga tgctcaagaa gaagcagctc gtctaaaaag
     9001 caaagcccaa gctgatatca ctgtagaacg tgattcagcg ctgaactctg taaaagacga
     9061 cgttgcagaa ctctctcttc aaatcgcgga aaaaatcttg aacaaagaat tatctccaga
     9121 aatgcatgaa tcattaatca atcaatacat tgaaggtcta ggttcttcaa atgaaactag
     9181 ataaatatac agtaggaaga cgttacggga aagctttatt tgaactggcg atcgattcaa
     9241 atcaagcaga agaaatctat caagatctcg taagtttacg tcaaatctat gaacaagtac
     9301 ctggattagg gaatatgtta agtgatgttc gtctagaacc tcatgaaaaa cgagaaatca
     9361 tggacaagct tgtcagcggt tatgatggga tcgttaaaaa ctttttagaa gttgtttatg
     9421 agtataaccg aatggatgac cttttgttca tgatcgaaga atatgaacgt cgatatgatg
     9481 aacatcaagg gttactattg ggaagtgtca caacagcagt cccactttca gacgaacaac
     9541 gaatacaatt agaaaagaat gttgcaaaaa caatggacta tcaatcagtt gaattaaaac
     9601 aaatcgttga ttcttctatt attggtggcg cgattgttga agccaaccat cgagtaatcg
     9661 acggaagcat tcgcacgcaa ttagaaaaaa tgcgtaatca attaaacaga tagtacaaag
     9721 aggtaggtga atcgaatggc catcaaagca gaagaaatta gtgccttgat taaagaacaa
     9781 attgaaaatt atcaaaacgt gctttcagtc gaagaaatcg gtaccgtaac ttatgtaggt
     9841 gacgggatcg ctcgtgcaca tggtttagaa aacgcgatga gtggtgagtt gcttgaattt
     9901 tcaaacggct catacggaat ggcgcaaaac ttagagtcaa atgatgtagg tatcattatc
     9961 cttggcgatt tcgagtccat tcgtgaagga gataaagtaa aacgaacagg taagatcatg
    10021 gaagttccag ttggagaggc cttgatcggt cgggtagtca atccgctagg tcaaccaatc
    10081 gacggactag gtgaaatcgt tactgacaaa gctcgtccag tagaagcgat ggcaccaggt
    10141 gttatgcaac gtaaatctgt taacgaacca atgcaaacag ggctaaaagc gatcgacgcc
    10201 cttgtgccaa tcggacgcgg acaacgtgaa ttagtcatcg gtgaccgtaa aacagggaaa
    10261 acttctattg cgatcgatac gatcatcaac caaaaaggtc aagatatgat ctgtatctat
    10321 gtagcaatcg gacaaaaaga ttctacagtt cgtacacaag ttgaaacatt gaaaaaatat
    10381 ggcgcaatgg attacacaat cgttgtgaat gccggtgcgt ctcaaccagc accattgctt
    10441 tatatcgcac catatgctgg tactgcaatg ggtgaagaat tcatgtacaa cggtaaacat
    10501 gtattgatca tttttgatga tctttcaaaa caagctgttg cttatcgtga actttccttg
    10561 ctacttcgcc gtccaccagg tcgtgaagct tatcctgggg atgttttcta cttgcactca
    10621 cgtttattag aacgtgcagc aaaattaagt gatgatttag gtggcggttc aatgactgcc
    10681 ttaccatttg ttgaaacaca agctggagat atctctgctt atatcccaac aaacgttatt
    10741 tcgatcactg atggacaaat cttcttagaa agcgacttgt tctacgcagg tactcgtcca
    10801 gcggttgatg ccggactatc tgtatctcgt gtaggaggtt ctgcgcaaat caaagcaatg
    10861 aaaaaagttg ctgggacttt acgcctagac ttagcaagtt accgtgaatt agaagcattt
    10921 acacaattcg gttctgactt ggatgcagca acacaagcaa aactaaatcg tggacgccgt
    10981 acagtagaaa tcttgaaaca aaaattgcat gcaccgctag ctgttgaaaa acaagtagtg
    11041 attttgtatg ctttgacaca tggattctta gatagtatcc ctgtagacag tattttagac
    11101 ttcgaacatg aattattcga atatctggat accaatcatt cagatatctt tgaaacaatc
    11161 cgtacaacaa aagatcttcc agaagaagaa gcgttgaaca gtgcgattca ggaatataaa
    11221 gacatgttct tagctacaaa aggaagtaat tcctctacag aagataaatt gaaatccatt
    11281 caaaatgcat agtgaggtga gatgaatggg tgcttcatta aatgaaatca agacacgtat
    11341 cgcttcaacg aaaaaaacga gccaaatcac gcgggcaatg cagatggtgt ctgcttctaa
    11401 gttgacaaaa tctgaagctt cttcacagaa gtttcaggtt tatgcaacaa aagtaagaga
    11461 aatcgttacg catttgactg ctactcagtt aaatgatatt gcctcagaaa atcctagagg
    11521 ggatatcaat tacaacagca tgctgctcag ccgtcctgtg aagaaaactg gttatatcgt
    11581 catcactgca gatggcggtt tagtcggtgg atataacagc tcgatattga aacaaacgat
    11641 gtctatttta gaagaagacc accaatcacc cgatgattac gtgatgatcg caattggcgg
    11701 aactggtgca gacttcttta aagcacgcgg tatcaatcta gcatatgagc tgcgcaatct
    11761 atctgatcag ccaagctttg atgaagtccg caaaattgta aatatggcaa caactatgtt
    11821 ccaaaacgaa gtattcgatg aattatacgt atgttataac catcatatca attcgctaac
    11881 tagtcagttt cgtgtagaaa aaatgctgcc aatctcagac ttagatccag aagaagcaac
    11941 gactttcgaa caagaatata tttttgaacc ttcaaaagaa gaaatcttgt ctcagttatt
    12001 gcctcagtat gctgaaagtt tgatctacgg tgcgatcgtt gacgccaaaa cagcagaaca
    12061 tgctgctggt atgacagcaa tgaaaacagc aactgataat gctgctaata tcattgatga
    12121 gctgacggtt tcttataacc gtgcaagaca aggggctatt acccaagaaa ttaccgaaat
    12181 tgttgccgga gcttcggcac tagaatagta ttgagattgg aggaaaaaag atgagttcag
    12241 gcaagattgt tcaagtaatc ggtcccgttg tcgacgtgga attttcttta gaccaatcct
    12301 taccagatat caacaacgca ttagttgttt ataaaaatga cgaaaataaa tcaaaagttg
    12361 ttcttgaagc agcgttagaa ttaggggacg gagtgatccg gaccattgcg atggaatcaa
    12421 cagatggttt acaaagagga atggaagtca ttgatacagg caaagcaatc tctgttcctg
    12481 taggtaaaga aacattaggt cgcgtattca acgtactagg agatacgatc gatttagaaa
    12541 cacctttccc agaagatgcg gaaagaagcg aaattcataa aaaagcacca gcctttgacg
    12601 aattaagtac aagtacagaa attttggaaa cagggatcaa agttatcgat ttgcttgccc
    12661 catatttaaa aggtgggaaa gtcggactat tcggtggtgc cggtgttggt aaaaccgtac
    12721 tgatccaaga actgatccat aatatcgccc aagaacatgg tggtatttct gtatttaccg
    12781 gtgtaggtga acgtactcgt gaaggtaatg acttgtatta tgaaatgaaa gattcaggag
    12841 ttatcgaaaa aacagccatg gtgttcggac aaatgaacga accaccaggt gcacgtatgc
    12901 gtgttgcttt gactggtttg acgattgcgg aatatttccg tgatgtagaa ggtcaagatg
    12961 tactgttgtt tatcgacaac attttccgtt tcactcaagc tggatctgaa gtatcagcct
    13021 tgttaggacg gatgccttct gcggttggtt atcaaccaac attggcaaca gaaatgggtc
    13081 aattgcaaga acgtatcaca tctacgaaaa aaggttcgat cacatcgatc caagcaatct
    13141 atgtgccagc cgatgactac actgacccgg cgccggcaac agcattcgcc catttggatg
    13201 cgacaaccaa cttggaacgt aaattaacag aacaagggat ttatccagcg gtagatccat
    13261 tggcttcttc ttcaagtgct ttagcacctg aaatcgtggg agaagaacat tataaagtag
    13321 caacagaagt ccaacacgta ttgcaacgat atcgtgaatt acaagatatc attgctatct
    13381 taggtatgga tgaattatcc gatcaagaaa aagtgttagt ttctcgtgcc cgcagagtcc
    13441 aattcttctt gtcacaaaac tttaacgtgg ctgaacaatt tactggtctt ccaggttcat
    13501 atgtccctgt agaagaaaca gtgaaaggat tccgcgaaat cttggaaggc aaatacgatg
    13561 atcttcctga agaagctttc cgaagtgttg gccgaatcga agacgtcgta gaaaaagcga
    13621 aaacactagg ctactagaaa ggggtgcccc atggatcaat atttaacagt aaatgtggta
    13681 actcctgccg gtttggtcta tgatcaccat gcagctatcg tcgttgcacg tacgacagct
    13741 ggtgagcttg ggattttgcc taaacatgca ccaatcatcg ttccattgac gattgatgaa
    13801 gttcgtgtaa aacgaacaga ttcagatacc cacgtcgatt ggatcgctgt taatggcgga
    13861 atcatggaag ttcgtgataa tgttgtttca atcgttgctg atagtgcgga acgtgaacgt
    13921 gatatcgatg tatctcgtgc ggaacgtgca aaacaacgcg cagaacgcca aatcgaagaa
    13981 gcaaaagcaa aacaagatac gaacgaattg aaacgggcaa ctgttgcgtt gcaccgagca
    14041 atcaatcgta tcaaagtatc taagcactca taaaatgaga tgcggatgtt tatccgtgtt
    14101 taagaacagt aaaaagaggt tatgacagaa gtggtcagct tcaagacata agaaggaatt
    14161 tacgaaaatt gcttctcaaa tttttgtgaa atctcagctt atttttcgaa gaagctactt
    14221 ctggaacacc gtatatcaga ggttgtgaaa tcagcgtttt gtcctgagta ttagagaaac
    14281 aaatggaaaa tagttcctca tattttgccg ttttttgagc taataccgag ggtcagatga
    14341 ttgaacaccg tttatttgga ataagggact gcgacaagac ttttgtctca gtcccttttt
    14401 ttgcatattt ttagcattta tttcctaaaa aatgtaaggg gattcctata tttttaagta
    14461 tacttgtttt tccttttata cattttatgg tattatcatt ttattagtta ttataaaaca
    14521 atcgttagaa aggacgtcat tatgcaagta tacggaattg atgcggtgct tcgaatcgtg
    14581 agtcatttgg cgtttatcta cttagccttc tggtctttac gttcgttacg cattgaaact
    14641 tttttcagac caatgcataa tacgcaaatt agaatggcaa tcgtactttt ttcaattttt
    14701 ttagggtaca ctgcaagtaa ttttttctta gaggttatcg ctttatgccg aaatcttttc
    14761 gttagcctgt aaattttaaa aaaaggtact attttaaaag caaggatgtt ataatagaaa
    14821 agattttgag taagtgtatg ctcattggaa ttttttggag ggaacaacat ggaagagatc
    14881 atcgtaagag gtggcaatca attaaatgga acagtaagaa ttgaaggagc taaaaatgct
    14941 gttttgccta ttttagctgc tagtttgtta gcagaagaag gtattacgac attagacaac
    15001 gttccgattc tttctgatgt cttcactatg aatcaagtga ttcgtcactt aaacgtagat
    15061 gtagattttg atgaacaaaa gaatcaagta acaatcgacg cttcaagaca attagaaatc
    15121 gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa tcgttgtgat gggtccgcta
    15181 cttgccagaa atggacatgc aaaagtagct atgcctggtg gatgtgcgat tggtaaacga
    15241 ccaatcgatt tgcatttaaa aggatttcaa gctttaggag caaaaattat tcaaaaaaac
    15301 ggctatatcg aagcaattgc ggatgaattg atcggtaaca cgatttattt agatttccct
    15361 agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa aagcaaaagg aacaaccatc
    15421 attgaaaacg tagctcgcga accagaaatc gttgatttag caaacatttt gaataaaatg
    15481 ggcgctcaag tctatggagc tggtactgaa acaatgcgta ttgaaggcgt ggatcattta
    15541 catgcagtca accactcaat cgtacaagat cgtatcgaag caggtacctt tatggttgct
    15601 gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta tctctgaaca taaccgccca
    15661 ttgatttcta aattgatcga aatgggtgca gaaatcattg aagaagaagg cggagtccgt
    15721 gtcatcggac caaaacatat cttacctaca gatgtaaaaa cgatgcctca tcctggtttc
    15781 cctacagata tgcaagctca aatgacagct atccaattag ttgcagaagg tacaagtgtg
    15841 gtgactgaaa cagtgtttga aaatcgtttc caacatttag aagagatgcg ccgtatgaac
    15901 gctcatgtca aaatcgacgg aaatgtagca atcatggatg gaaaccatga attgcaaggt
    15961 gcagaagtat atgcaacaga cttgcgggca gcagcagcat tagttttagc tggcttgaaa
    16021 gcaaatggaa tcacacgtgt gcgtaacttg aattatctag accgtggata ttataatttc
    16081 catatcaaac tacagcaatt aggtgcagac gtcgaacgtg tagacatgga tcaaacttct
    16141 gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct gaatgagtaa ccaacgatat
    16201 atcttattaa ctttgataaa gattttagtg gtgatcttat tgcttatcct tctttttgtg
    16261 gccggaacga tgatcggata tggtgtcatc ggtggcggca atccatttaa agtattccag
    16321 ccaagtttgt ggattcatat tcgagacttt tttcattgat aaataagaat cacagtggtt
    16381 ctagtcgata tgaagtgagc catgaagcag aacatgataa aagaaaacag aagggaacgt
    16441 tgacgttagt cgcgatccct ttttttagta aaagaaaaga aggaatctaa ttgatgaaga
    16501 agatattgat ttatttagtt agaggatatc agcgctttat ttcgcctgca tttccaccta
    16561 gctgccgtta ttacccaacc tgttccaatt atatgataaa agcaattcaa acccatggtg
    16621 cgctaaaagg gacggtaatg gggactgcac ggatcttacg ctgtcatcct tttgtcaaag
    16681 gcggtatcga ttatgtacca ttgacattcc gattaacgcg aaataagaaa gataaaaaag
    16741 aaccagatta taaaaaggtt gtgaaaaata cgggtagcac tgagcgataa agaaaaagag
    16801 gaaatttatt gtcaaagtaa caactccgca actacttata tgggggacaa aaaatgatcg
    16861 aagaactaaa caagaaagat ttaccatggt ccttgttatt agatgcagat cctgataaag
    16921 aaaaagttca agtatatgtt tccagaggga gtggctggat atggaaagaa aaagaaaaaa
    16981 caataggtgt actgatctat gtggcaaggg aaaaagaata cgaaatcgtc aatgtagcag
    17041 taaccccaac gtatcaagga aaggggattg gcggaaaatt acttgagaca gcttttcaga
    17101 agctttcaca gctagcttca aaccaaactc ggatcattat acgtactggc actactagta
    17161 gcgctgcgtt acacctctat caaaaaatgg gctatgtgga gattggtcga gtcaaagact
    17221 attttatcca tcattactct gagcccattt ttgaaaatgg agatcaatta agggatcaag
    17281 tgattttagc aattcactta cctaaaaata gctttaacta ataaactttc aattcgagaa
    17341 aatgctttca aatgctaaat agatacatta caatagcttt agcaaacaaa aaggagaata
    17401 tttttatggg aatattagtt tttgattttg gtggatcggc tgtcaaatat ggttgttggg
    17461 atggcaaaga gattaaaggt aagggacaat ttgcaacgcc tgaatcttgg gaagaaatga
    17521 aaacgcaatt atttcaagtt tataaaaaaa tactcgtttc ttttgaagtc gaaggaattg
    17581 gaatcagctc tcctggagta gtgaataatg agaaacaggt gattgaggga atcagtgcga
    17641 ttccttatat tcatggattt aatattttcc gagatttgga aactctgttt caactcccag
    17701 taacgattga aaatgacgcc aactgtgccg gaatggctga attttatgaa ggtgctgccc
    17761 gtgattatca agatgttgct tttgttgtgg caggaactgg gattggcggg gcgttgttca
    17821 cgaaaggaca aataaataaa ggggcacatc tttacggtgg agaatttggg ttgatgttct
    17881 tagatggcga taagacattc agtaaacttg gtacagcggt acagatggct tggcgttatt
    17941 gtgaacgcaa aggtctcgat aaaaatgctt ataccggaaa agatgtcttt gaattagcag
    18001 aaactggaga tgcaatagca aaagaagaag ttgagagttt ttatacgtat cttacaaagg
    18061 gattattcag tattcaattt tcgtttgatc cagaagtgat cgtattaggc ggcggggttt
    18121 ctgcaaaaga agggctcatt gatgagatca aaagccgaat gaagaagctg acagaacaat
    18181 tcgatctgca tgatttcgaa ccgcagattt tattatgtga gtacagaaac gatgctaatc
    18241 ttataggtgc agcagcaaac tatctcgctg tacgtcaagg agagaattaa gagctttaga
    18301 gaaggtgcag cttgcataaa agaagagaat gaaatgaata ggagattttt acctaaggaa
    18361 tgttttattt gctgcagtat gataaaatat ctgagaggtg aaaatgatgt caaaaaaaaa
    18421 taaagatatt gaagtgcgta tagaagaagt gaaaaaagat atcaaaggta agaattatga
    18481 agtcactcag ttatttatag ggaaaaaaat gattggtgag atcttagcct atgggccaaa
    18541 agaatatgaa attttctttg gtgaagaaga ttttggaaaa gaaaaaagtc ttgaaaatgc
    18601 gatagaaaca gtgattcgac actggaatct gcacgaataa aaaaatatca aaaaaacttt
    18661 caataaaggg ttgcaaaaat ctggaaaatt aggtattata actaagtcag gttgatacaa
    18721 acctttcgga ggagtagcga agtggctaaa cgcgacggac tgtaaatccg ttccttaggg
    18781 ttcagtggtt cgaatccact ctcctccatt tcattggggt atagccaagc ggtaaggcaa
    18841 gggactttga ctccctcatg cgttggttcg aatccagcta ccccagtata ccacaatcgt
    18901 aagctctcgt tagttcgaga gctctttttt tttgctttgc taccttgttc cttgaagatt
    18961 ctgctgaatt aagatagagt taagttaact acaagaattg gagggatcca catgaaatgg
    19021 aaagaaaaag tagacgaagc agctgaaaag ttatatgatt tggtcaaatc agaaaaatac
    19081 aatattgaag tgaatattcc gaaaaaaggc ggaaaagcgg tccaggtaaa atcaaaacgc
    19141 ccaacgaatc atacaaaaaa atggatggct aaaaaccgct aataataaca aaagatccat
    19201 aagtcggcat tttcatcgat tttagggtct tttgttattt tctaggttga acatatctaa
    19261 aaaattgttt ctgacaatag gagtagggag aacgatgtgt gtctaaatcc tctgttgatg
    19321 gatagaaacc tttatctttt tcagttgtga atcaggtata taccagttat aatagaagaa
    19381 acgaaaggac gggtgtacgt tatgtcgaat caattacctg tatatataca gattcatgac
    19441 caattaaaaa atgaaatcga acaaggtata tggaaagtcg gagaccgtct tccttcagaa
    19501 agagaattag cagtgaaatt caatgtcagc cgtatgacgt tgagacaagc aattcaaaac
    19561 ttggcagatg aaggaatctt agaaagaaag atcggttcgg gtacgtatgt tgcgcgagaa
    19621 aaagtacaag aaaaaatgtc tggtgcaaca agttttacag aaattatgga atcacaaaat
    19681 cgagtaccgt ctagtcggac aatctcttat ttcttgactt cgccaagctc aagtgaaatg
    19741 gaaaaactaa acttgagtaa agatgacacg atcttgcgaa tggaacgtat tcgtttcgca
    19801 gatgatgtcc ctatttgttt tgaagttgcc agtgttccac aaaagctgat cgatggctac
    19861 agcaaagcag agattactga atcgttgtat cgcacgctag aagaaaaagg cgggaaaaag
    19921 atcggtccag cgaatcaaac gattactgct gtgttggctt ctgagaaaat tgctgactat
    19981 ttagaggtaa aacgaagaga tgcagttctt cgtttgcgcc agatttctta ttttgaagac
    20041 ggtacgccgt ttgagtatgt gcgtacgcaa tacgtaggaa atcgttttga gttttatttg
    20101 gaaaaataaa aaacaggtga tccctgattc cttattagaa ataaaagaga atcagaatca
    20161 cctgttttta tatatgatca gttatcagtt gctcgtgata agaaacagaa ccctcttcaa
    20221 attggacttg tccgttcagc agctcaatga tggattcttt aaagtggtta gcactttttt
    20281 catctacagc acagatgacg ctaacttgat cagtatattg gatttctttt ataaaaaaat
    20341 gttggagttc aagataattc tgtaattttc ctagttgcgg atacgtgatc atcacagaga
    20401 tctcctgttg caaggtacct tctacgattc caatgtcaga caatgcttga gagaccgcat
    20461 gagtgtatgc tcgtattaat ccgcctgtgc cgagtttcgt tcctccaaaa tatcgagtga
    20521 ctactgcagc tacattgatc agttgatttt ttttgaggac ttccaacatc ggtacgcccg
    20581 ccgttccact tggttctcca tcatcgctgc ttcgctggat ttcatttttt tctccaatga
    20641 tgaaggcgct gcagttatgg ttcgctttcc aatgttcttt ttttatttct tgaatgaaat
    20701 tttttgcttg gtcctctgat tctattcgtc taagagaaca gataaagcgt gattttttga
    20761 tctcaatctc actttgtcca ttttctttta ttgtacgata gcgctcgatc atcttgtcac
    20821 ctcttttttt cattttcttt attcagtata aataaagttc taggttgttt caacactgta
    20881 acggttgcgc aattgctgta gtatgcgata ataaagacaa aggcaggtgg atctggggat
    20941 gcaggaacga atgaaaaagt acgatgcaat tacgcattat ttgaagaaca atggcggctc
    21001 tcaagtaacg ttgaccttta cccaatttga cgaactgctg tttcccagta acggacttcc
    21061 caaaacagca agggaaagta cagattggtg ggcaaatgat tataaacacc ctgaaaaagg
    21121 tgcctatggc tggataaatg caggctatga agtagttgtc atcaatttgg acaaagaata
    21181 tgtcgtgttc aataaattag tgaaatctag ttggctattt gattaaataa accgcgttta
    21241 gaaaacgttg acaaatttct ttctttttat ataataaagt aacagacgcg aagaaaacgt
    21301 ttgcgtagtt tgttttaaaa aggagagaaa aatatggcta aaaaaacaat catgcttgta
    21361 tgttcggctg gtatgagcac aagtttacta gtaacaaaaa tgcaaaaagc tgctgaagca
    21421 aaaggaatcg actctgatat tttcgctgtg tccgcttctg acgcagataa caatcttgca
    21481 aataaagacg tggatgtgtt gttattaggc ccacaagttc gctttatgaa agctgatttt
    21541 gagaaacgtc tggaaccaaa aggcattcct ttagatgtca tcaatatggc tgattatggt
    21601 atgatgaatg gcgaaaaagt gttagatcaa gcaatcgcgc tcataggtga ataaatagaa
    21661 cagtataact atcgaacaag cgatccaaaa aatagatcgc ttgttttttc gtatattttt
    21721 ttagggcgaa taatatgaat catttttggg gtagaaggct tctgacgaga gatattaaag
    21781 caatagactg tgaggaggta aatttaccaa attatgagaa gatcgcagca gtggaacgtt
    21841 tgggcaactg gattctttgt catcgctgtg gaatgaggac gtccgtcatt gttggacagc
    21901 ttgcagatta cggttatttt tgtacacatt gtctatattt agggtgatgc gacactcaac
    21961 aagatttata tttgtttgat cagcctgaag caaaacctcg agaagtcgtc tttttttgga
    22021 caggacagct tactgaaaaa caaacggaaa tcgcaaagag aatactttgc cattcagaaa
    22081 aaagacatca tcttatttgg gctgtaacag gtgcagggaa aacagagatg ctttatccta
    22141 ttttagtgga aactttaaaa gctggaggaa gagtagcgat ttgtacaccg cgagtcgatg
    22201 tttgtaatga attgttttta cgctatcgtt atgtttttcc agaagaaaaa atcacgttgc
    22261 tccatgggaa tacagcaacg gcttatacct ttacttcttt tgttatctgt acgattcatc
    22321 agctataccg tttttatcgg tcctttgatt taatagtgat cgatgagatc gatgcgtttc
    22381 cttataacgg ggatgctggg ctagctcacg ctgtgcaaac agcaatcaga tcaaacggcc
    22441 gattcatcta cttaagtgcc acgcctgatg agaagttact aaaggaaatc aagcagacat
    22501 ttgagctcca caaacttgcc ttgcgctttc atcggcgctt gcttcctgaa cccgtgcttg
    22561 ttttcatgaa taattggcga caaaaatgtg gaaacaaaaa gaaaatcaac tctttggtgc
    22621 ggatcattca gcaactaatc aaagaaaacc gtatcctttt attttgtcca agtattacga
    22681 tgatgcatcg tttaaaaatc acactgcaag aagcttttcc agaatatgag ataacagatg
    22741 tttcttcaca agacgatcaa cgggcaaaga aagttcagaa aatgcgagaa gcaatatacg
    22801 agatactgtt aaccacaatg atcctagaaa gaggagtcac atttgaaaga atctctgtca
    22861 tcgttttagg agcagatcat ccagttttta ctaaatcctc tttggtgcaa atcgcaggaa
    22921 gagctgatcg taaaggtcct tatacgaaca gtcgagtcta ttttttctat gaagaaaaaa
    22981 cttcagctat tcgaaaagcc tgtcaggaaa tcaaagaaat gaacgaagaa gggaagcaga
    23041 tgctgtgaga tgtagttgct gcggtaaaga catcattcaa aatttaacat tcagcgagat
    23101 catcggagtg tcgaaatcta gacttcctca gacatgttca gtttgccgcg cacaattcca
    23161 tttattagaa gcaaaaggtt gtgcaggttg tcaaaaacca atccatttga aatacgagga
    23221 gacgaaaaag aaagcaaata ctagtttcgt ttactgcaac gactgtcaag aatggaagaa
    23281 gaaatatcct gcatatgatt ttcaacaccg cgcctttttt acgtacgatg aaaagatgca
    23341 ggcttggatc aatcggtaca agtttatggg agatatccga ttagcaggga cttttgcata
    23401 taaatggact cagataaaaa aaagattacc cggcatatat ttattgtcca atacctttat
    23461 ctgaaaaaag gtggctagaa agaggattca atcaagtaag cgagatgttg aaagcagcaa
    23521 aaattccttt tcagatgctg ctcaaaagag agcaacatct gcttgctcaa gcaaaaaaca
    23581 cgcgaaagga aagattggag atgcctcagc cttttgagct tgccgtacct ctttctaaga
    23641 tacaacataa aaaa
//
LOCUS       DADGHT010000039        23484 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.039, whole genome shotgun sequence.
ACCESSION   DADGHT010000039 DADGHT010000000
VERSION     DADGHT010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.039"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..337)
                     /locus_tag="JX887_001398"
     CDS             complement(<1..337)
                     /locus_tag="JX887_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1257394.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQ"
     gene            610..3081
                     /locus_tag="JX887_001399"
     CDS             610..3081
                     /locus_tag="JX887_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAX1257395.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3184..4920)
                     /locus_tag="JX887_001400"
     CDS             complement(3184..4920)
                     /locus_tag="JX887_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAX1257396.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(4917..5621)
                     /locus_tag="JX887_001401"
     CDS             complement(4917..5621)
                     /locus_tag="JX887_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1257397.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5752..6255
                     /locus_tag="JX887_001402"
     CDS             5752..6255
                     /locus_tag="JX887_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAX1257398.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6215..6553
                     /locus_tag="JX887_001403"
     CDS             6215..6553
                     /locus_tag="JX887_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAX1257399.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6574..7992
                     /gene="ffh"
                     /locus_tag="JX887_001404"
     CDS             6574..7992
                     /gene="ffh"
                     /locus_tag="JX887_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAX1257400.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8104..8682
                     /locus_tag="JX887_001405"
     CDS             8104..8682
                     /locus_tag="JX887_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAX1257401.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8686..9207
                     /locus_tag="JX887_001406"
     CDS             8686..9207
                     /locus_tag="JX887_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAX1257402.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9286..9840)
                     /locus_tag="JX887_001407"
     CDS             complement(9286..9840)
                     /locus_tag="JX887_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAX1257403.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10093..10368
                     /gene="rpsP"
                     /locus_tag="JX887_001408"
     CDS             10093..10368
                     /gene="rpsP"
                     /locus_tag="JX887_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAX1257404.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10380..10631
                     /locus_tag="JX887_001409"
     CDS             10380..10631
                     /locus_tag="JX887_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAX1257405.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10756..11547
                     /locus_tag="JX887_001410"
     CDS             10756..11547
                     /locus_tag="JX887_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257406.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11717..12238
                     /gene="rimM"
                     /locus_tag="JX887_001411"
     CDS             11717..12238
                     /gene="rimM"
                     /locus_tag="JX887_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAX1257407.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12228..12989
                     /gene="trmD"
                     /locus_tag="JX887_001412"
     CDS             12228..12989
                     /gene="trmD"
                     /locus_tag="JX887_001412"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAX1257408.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13125..13472
                     /gene="rplS"
                     /locus_tag="JX887_001413"
     CDS             13125..13472
                     /gene="rplS"
                     /locus_tag="JX887_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAX1257409.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13845..14507
                     /locus_tag="JX887_001414"
     CDS             13845..14507
                     /locus_tag="JX887_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257410.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            14586..17813
                     /gene="fss3"
                     /locus_tag="JX887_001415"
     CDS             14586..17813
                     /gene="fss3"
                     /locus_tag="JX887_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAX1257411.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            17927..18241
                     /locus_tag="JX887_001416"
     CDS             17927..18241
                     /locus_tag="JX887_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAX1257412.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            18254..18628
                     /locus_tag="JX887_001417"
     CDS             18254..18628
                     /locus_tag="JX887_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAX1257413.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            18638..18982
                     /locus_tag="JX887_001418"
     CDS             18638..18982
                     /locus_tag="JX887_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAX1257414.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            19053..20405
                     /locus_tag="JX887_001419"
     CDS             19053..20405
                     /locus_tag="JX887_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAX1257415.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            20465..21607
                     /locus_tag="JX887_001420"
     CDS             20465..21607
                     /locus_tag="JX887_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HAX1257416.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            21632..21886
                     /locus_tag="JX887_001421"
     CDS             21632..21886
                     /locus_tag="JX887_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257417.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            22142..23326
                     /locus_tag="JX887_001422"
     CDS             22142..23326
                     /locus_tag="JX887_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAX1257418.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            23341..23460
                     /locus_tag="JX887_001423"
     CDS             23341..23460
                     /locus_tag="JX887_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAX1257419.1"
                     /translation="MEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKGK"
BASE COUNT         7789 a         4179 c         5038 g         6478 t
ORIGIN      
        1 cctgcttcag ttcctttgtt agttgatgat gttcatcaac taagtccgtt ttcgcagaaa
       61 aggtccttcc acaatcatgg cagagaaaac gggtacgttt taattctaaa atagttaact
      121 tttctttgac tttcaacatc tgagtgcgtg tcgtatagga accgttgcgg ataatacgaa
      181 ccgatcgaca gtgttcacaa taggaagaag agtcatccaa ttttccttta ataaactgcg
      241 cttgaacgcc tttatattct ttttcaatca gccattcttc atcaaaaaat aaatgtttat
      301 ctgttaatcc gagtaatttt ctagtatgat tatccattga gagactcctt tggtaggatg
      361 acgttttggt cgactaaatt ttaccaaaag tgagtctctt tttgagttga aacgaagaaa
      421 aagtgttagt agaaaatcgc cttcgatttt ccaccaacac aaaatattat agaacccttt
      481 ttttttgcta tatgacagga atgaaaggtg tttgcaagct taatgtgagg aacactttcc
      541 atatctgttc tatactggat aggagaagtt tggaaatatc cagaaaacga aatcaatcga
      601 ggtagccaca tgaagaataa atggataaat cgaagtaaaa aaaagaaagt aacacaaaga
      661 tcatcagata aagtcatccg tctttttcca tcgtataaag aaggattaac ggcagatcaa
      721 gtcaaggaac gaatagaaaa aggtgcagca aataattcag tcgatcccac attcaaaaca
      781 aatcagcaaa tcgtattgga aaacatattt acgtatttca atttgatctt tcttatctta
      841 gccattttgc tttgtttagt agaatcctat aagaacttga cttttttacc agttatcata
      901 gccaatacag gaatcgccat ttttcaggaa attcgatcca aaaagatctt ggacgaacta
      961 aatgttttaa atacagcaaa agtcaatgtc atacgagacg ggatagaaca aacaatagat
     1021 atagaagacc ttgtaataga tgacattgtt attttagaga ctggatatca aattccagca
     1081 gatgcagagg tcgtggaagg gaaactgcaa gttaatgagg ctttattgac aggcgaagca
     1141 gatgaaataa ccaaagaaat aggtgatcca ttaatgtccg gcagtttcat tgtttccgga
     1201 aaagcttacg cccgattaga caaagttgga gcagattcgt atatttccca gctgacagtc
     1261 aaagccaaga caatgggaga aggagaacag tcggagatga ttgcttctct taatcaattg
     1321 atcaaatgga ttgggatcat cattattcct atcggtatcc tgcttttttc tcaaagttac
     1381 ttttttaatg gaaacacgat caaagaaagt gtcgttgcaa tggaagcagc attgatcggt
     1441 atgatacctg aaggactgta cttgctgacg acgattgcat tagcattaag tgcgactaaa
     1501 ctagcaaagc aaagagttct tttacacaat atgaaaagca ttgagacatt ggcaagggta
     1561 aatgtccttt gtgtagataa aacaggaacg atcacagaaa ataaaatgtc tgttcaaaaa
     1621 atgatcgtct ctaaaaaaca agaaataatc agtcagtcag atcaattgga agcatgcatt
     1681 gctgactatg caaaagcgat ggcaggagac aatgcaacaa tggaagctgt taaagcatat
     1741 tttacaaaaa ccactgatca atcctatcac catgttattc ctttttcttc tgtccaaaaa
     1801 ttcagcagtg tagcgttggc agacaaggtg tatgttttag gagcgcccga aatggttttg
     1861 cgcgatcaat tgccggaata tgcggaagag tttgtttctt tcgctgaaaa aggctatcgc
     1921 gtgttggtct ttggtgtgta cgatgggatt cttgaagaac cagtattgac agaagcagtc
     1981 acaccattag gctatattct gattgctaat cctatcagaa aagaagcaag agccacattt
     2041 gattacttca aaaaacagca agtagccatc aaagtgattt ctggagataa tccgctcacc
     2101 gtatccaatg tagctgtcca agcagggatt tcacatgctg atcagtacgt tgatgcatct
     2161 aaattatcag aagaagaata tgaagcagct gtcgaaaaat atacagtttt tggacgcgtc
     2221 aagccagaac aaaagaaaat cttcgttcaa ttgataaagc gtaacaatac agtagctatg
     2281 acaggtgatg gcgtgaatga tattctagcc atgaaagaag cagactgcag tatagcgatg
     2341 gcttccggaa atgaagccgc catgcaggcc tcacaagtgg tcttacttga ttctgacttt
     2401 tcacgcatgc cagaagttgt tgcagaagga cggcgcgttg tgaacaatat tgagcgatca
     2461 gccagcttgt ttttagtgaa gaatattttc tcctttttgc tctcactgtt ttcagtgatc
     2521 tttgctctga cctatccttt agaaccatca caaatcacat tgattagttt gtttactatc
     2581 ggacttccat ctttcttgct tgctctagaa gaaaacaaaa agcgaatcag agggaaattc
     2641 atcatgaatg tgatggaaaa agctgtgcca ggtggactaa cagatatgat cgtagtcggt
     2701 gcgttggtga tctgcggggt gactttgaat ctaaataaaa cagatgtttc tacagcatct
     2761 accatgcttt tgattgcagt agggttcctc gttctctata aaatctgttc accgctgaat
     2821 aaattcagaa gtcagatcat tcttttctgt gctagcggta actttttttc ggtcatcttt
     2881 ttgcataagc tgttttcaat caccggtatc tcagctgtat cacttttgct gttgagcatt
     2941 ctatttttct cggcagattc gatttttagg catttgacca cattggtaga atatttgttt
     3001 gaacgtaaaa atgaaaaaga gcaaaagccg tttagtcgcg tagctaaaaa atttctatcg
     3061 atatttaaac gagaaaattg acgaaaagta tctcaaaaaa gagtaaaaaa gaacaaccac
     3121 tcgtgtatct ttcgaagcag gatgagtcat ccaactttaa aacgcacgag cagttgctct
     3181 tttttacatt ttcggaatgg taacggtgaa agtcgaacct gttccaagat gactgtctac
     3241 agtaatcgta ccattaagga gttgcacgta gtcttttaca atcgctaacc ctaatccggt
     3301 cccgcctgaa tgtcggcttc gcgccttgtc tacgcggtaa aaacgctcaa agatccgttc
     3361 ctgatcctca atgtcgatac ctataccaaa gtcttggaca gaaaacgata gatcatctgt
     3421 tgcctgatag cggataataa tctcgctgtc gctttttgaa tattggacag cattttcaat
     3481 tagatttttg ataattggat aaaggatatc tgttttagta gtaaatggtt cgttctttcc
     3541 aatcaatcga atcgtcaacc gtttcttttc gatgattggc tgataatttt gaacgatttg
     3601 ctggaaataa ggttctgtat aaattgtctg gatctcgtaa gaattctcgc catcttttga
     3661 cagctggatg atttcccgaa tcagtttatc taaccggatc gcatcttttt gcatgatctc
     3721 aagaaaagaa gtcagagttt gcgggtcatc ttttgcacca tccagtaaag tctcggtaaa
     3781 accaatcagt gaagtcacag gagtttttaa ttcgtgagag acgttgccaa cgaaatcctt
     3841 ttgtagcttt tctaaacgtc gcactttcgt taagtcatac gccaccccta gaatctgtcc
     3901 ggtaccttct gaattagtaa agtagcgcaa actcaagtct aatgtctgcc gaccttctgt
     3961 aagggtgatc tcctgatgga tcagcggatg ctcaggagtc acttgatgaa tcagctgaat
     4021 gagttttggc tcttgaatga cttctgtgta ccgctgttca ggttgatagc ttaccacgtt
     4081 taaatgtagc tgcatctttg gattaagcag tagtaaacga gaatcagcat catcaatcag
     4141 gaatacgcca atcatcagtt cgttcagtaa cgtatataat tgctcttctg tggtagtaca
     4201 cgcccgatac atcttactca tttgttcgct caacgcatta atcgtctgat acaattcttc
     4261 ccattgatcg ggtgtttgca tgattacttc cgcctgatta ggattttgca ccattttttt
     4321 tagtacgggc agcacggttt tcaatggctg gtttttttga tagatcagat aatagatcat
     4381 tcctgcaaga acaaggaaga aagacagaaa gaagaaaaag acccaacggc gaaaactctc
     4441 agttctcggt aaaaaaccgc ttgtcggttc tgcgatacgt aaaatggctt ctaactggcc
     4501 actttttttg actggtaatg cgacatataa aagatcctca ttcaaagtag tacttttgcg
     4561 caaagcgcta cctaggttcc caccattcaa tacggctttg atttcgggac gggagtttcg
     4621 ctgttcattc aatgtttcat tgtttgtgtc aaataagatc tttccagtag catccattaa
     4681 agtaatccgt tcgttcgact gatggacgaa ttcttccaaa gcagttttgt tttgcgctgc
     4741 ttggaggttt tcgacatcta attgccggat cagcagttgt gctttttttg tcaggtagct
     4801 ttcttgctgt tccacgatct gctgttgaaa ataatgggaa atcaattgcc agccaccaaa
     4861 aaacaaacta actaaaagaa taagaaagaa gagacgttca taaatttttt tccatttcat
     4921 cgtttgggtt cctgaaactt atagccaaat cctctaatag tcaccaagta ctttgggtgt
     4981 tttggatctc gctcgatttt ttctcgcaaa tgactaacgt gtacatctac gattcggctt
     5041 tgtcctgcga agtcaaaatt ccaaatgcgg tctagcaatg tgtctcggtc gatcacacgg
     5101 tcttttcgtt tcatgaaata aacaagtaat tcaaattctt tcggtgttag ttcaatcaga
     5161 tggtcgtcta cggtcacttg ataattggtc aaatcagcag tgatttgtcc aatcgataga
     5221 tattcaggct cagcttcatc ttttgattgc ttacgaggtt caattcgtct gaatattgct
     5281 ttcatacggg ctaatacttc gcgaggacta aatggtttgg tcaaatagtc gtcagcacct
     5341 atttctaggc caatgatccg atccacttgg tcatctttag ccgtcagcat caaaatcggt
     5401 gtttcatttt tttcttgacg cagccgctga gtgatctcca tgccatccat cgttggaagc
     5461 atcacatcta aaatgatgaa atcaaatgat tgttctaatg ctaattctaa tccttcgcct
     5521 ccatctgtgg cactggttac cttgtagcct tctttttcca aattgaacgt caagagcgtt
     5581 acaatagaag gttcatcatc aacaactagt atttttttca ttcaaatctc ctttaaatag
     5641 gtttcattct gtttatattt tagcatagaa tcagtacaaa gggctatttt acaaaagaaa
     5701 taaatggtat aataggaagg cactttgctg aatagaaagg aagagcagtc aatgattgga
     5761 atcagtgcat gtttaggcgg tctggcctgt cgctatgatg gacagaaaaa agaagtacca
     5821 gaattgatgg aactagttga aactggagaa gctgtcatgg tctgtccaga agtgatcggc
     5881 ggattaccaa ttcctagaga tcccgctgaa atcattggtg gaaatggatt cgatgtgtgg
     5941 aaagatcaag caaaagtatg gacgacaagc ggcgaagatg taacggaagc gtacaaaaat
     6001 ggcgcgatca aagcctatca aaaattgcag gaaaaacaca ttgatctagt catcatgaag
     6061 gaaaaaagcc cttcatgcgg aacccattcg atttatgacg gaagtttttc cggaataaaa
     6121 aaaaatggtg ccggagtggc tactgcttat tttattcagc aaaaaatgac tgtgctctct
     6181 gatgaagaat ggctgaaaac tagaggtgag cagaatggaa atcgaaaaga ccaatcgaat
     6241 gaacgcgctc tttgaatttt attcgacctt attgacagaa aaacaaatga actacatgga
     6301 attatattat gcagatgatt tttcattagg tgagatcgcg gaagaatacg aagtaagccg
     6361 acaagcagta tatgacaata tcaagcggac aagcaagatc ttggaggatt atgaaaaaaa
     6421 actccatctt ttttctaatt atattgttcg agaacaggta ttggaaaata tgactgcata
     6481 tattacagat aagtacccgg aagataaaaa actacttgaa tatgtacagc aaattcaagc
     6541 aatcgaagaa taaataaaag gaatgaagaa aatatggcat ttgaaagctt aactgaacgt
     6601 ctccagcagg cgatgggaaa aataagaaaa aaaggaaaag tatcagaagc tgacgtaaaa
     6661 gaaatgatgc gggaaatccg ccttgcctta ctagaagccg atgttaactt gcaagtagtc
     6721 aaagatttta ctaagcgcgt acgcgaacgt gcggtagggg cagaagtgct ggaaagttta
     6781 tcacctgcac aacaaatcgt aaaaatcgtt gatgaagaat tgacgatcac acttggttct
     6841 gaaacagcag agttaaataa atcaccaaaa ataccaactg ttatcatgat ggctggtctt
     6901 caaggggcag gtaaaacgac ctttactggt aaattagcca attatttaaa gaaaaatgaa
     6961 aatgctcgtc cgctcctaat cgcaggggac gtatatcgac cagctgcgat cgaccaattg
     7021 aaagtattag gtcaacagct agacgttcct gtatttgata tgggaactga agtcagcccg
     7081 gtagagatcg tccgtcaagg gatggagtta gcaaaagaaa agaaaaacga ctatgtattg
     7141 atcgatacgg caggacgtct gcatatcgat gaaacattga tggatgagtt gaaacaaatc
     7201 aaagaattga cgcaaccaaa tgagattttg cttgttgtcg atgccatgac tggtcaagat
     7261 gccgtcaacg tagctgatag cttcaaccag caattaggta ttacaggggt cgtcatcact
     7321 aaacttgatg gggatactcg aggcggggca gcactatcga tccgctcagt gacaggcgca
     7381 ccaatcaaat tcatcggttc tggtgaaaaa ttgactgact tagaagtatt ccacccagat
     7441 cgtatggcta gccgtatcct tggtatgggg gatatgctga cattgattga aaaagcgcag
     7501 caagactacg acgagaaaaa agcggaagaa cttgcacaga aaatgcggga aaattcattc
     7561 gatttcaatg actttattga acagcttgat caagtgatgg gtatgggccc actggaagat
     7621 ctaatcaaaa tgatcccagg aatgaatcaa gtccctggaa tcgaaaacgt caaggtagat
     7681 ccaaaagatg ttgaacgcaa aaaagcgatg gtttattcta tgacgccagc agaaagagca
     7741 aatcctgatc tgttgaaccc aagccgtcgt cgccgaattg ctgccggttc tggaaacagt
     7801 gttgttgaag tgaatcgaat gatcaaacaa ttcaaggaat caagaaaaat gatgcagcaa
     7861 atgtccaaag gggatatgaa catcccaggt atggaccaaa tgtttggttc aggcgtcaaa
     7921 ggaaaactag gcaaaatggc gatgaatcga atgatcaaga aaaataagaa gaaaaagaaa
     7981 aaacggaaat aagatgaaaa aaacagcttc ggtacagact gaaaatgtct actgccggag
     8041 cttttctatc agcaattttt attctttact aatacaatta ctctaaacga agaggtggca
     8101 cagatgagat gtccgtggag tgaacaaaca gaaagtatgc ggcaatatca tgatactgtc
     8161 tggggtgttc ctgaatatga tgaccaaaag ctgttccgaa aattgatgct tgatattaat
     8221 caagccggat tgagctggca gacgatttta aataaaagtg aagcattcga tgaagcatat
     8281 gatcgattcg atatcaaaaa agtcgcaaat tatggagaaa caaaaatcag tgaactaatg
     8341 gaaaacaaag gaattattcg taaccgaaga aaaatcgaag cagccgtcca aaacgccaaa
     8401 gcagtcttga aaattcaaga agaaatcggc agtttttcag agtatctttg gtcgttttct
     8461 aatggaaaaa tcgttgattc ttcttatcat tcacaagaag aagtcccaac aacaagtcct
     8521 ctttcagatg aattagcaaa agatctaaag aaaagaggat ttaaatttat cggaagcaca
     8581 acaatctatg cttttttaga agctgtcggg atcatcaatg atcaccttga cagttgtttc
     8641 cgcaaagaag aggtcgtacg tatcggcaga aagggcgaat aaagcatgcg aaaaatcata
     8701 ttttatggtg ctataagttt agatggctat ttggcaacga aaacggatga tcttcaatgg
     8761 ctttttgaca ctccaacagg taagcaaact acttatgaag ctttttatga aacaatcgat
     8821 acgaccatca tgggcagaaa aacttatcag gaagcaaaaa aatatttgga gaccgaagca
     8881 atttatccag agaaaaagaa tttcgttttt tccacccacg cacaattaca attgccagat
     8941 gctgaggtcg taaacgaaga tcctgttgct tttctaaaaa atctacaaat gacagaagga
     9001 aaagatatct gggttgtggg tggcggtcga ttgatcaaac cgctattgga acatcaaatg
     9061 attgatgaat ggtatatcca gattacccct gtattattag gggacgggat tcctttattc
     9121 caaaaaggaa catatgaagc gcgttttgaa atgctagaca cgacacgatt cggtgaattt
     9181 atcgaattgc attatgtacg aaagtagaag taaataaaat aaaaaaggca actatatgca
     9241 gaaatgtcct gtacatagtt gcctttttta ttaccgttat gctttttact ctgttaattt
     9301 gttagaaaaa tctagatacg catctaaaat cgtttggaag aaacttaatg ttccttcaac
     9361 gatattacca ttttcatcaa ttagattcgc aacgtttccg atatatgctt ccggttgctg
     9421 caaggttggc acattcaaaa agacaagtga ttggcgtaga tggtggtttg cgccaaagcc
     9481 gccgatccca cctggtgatg cagtaacgac taaacctggt ttatgatccc aaacactgtg
     9541 tccataaggt cttgagccta catctaaagc atttttcaat actgctggca cagaacggtt
     9601 gtattcagga gtaacgaaaa cgacaccgtc tagtcccctc acttcctcac gaaaacgagt
     9661 ccattcagca ggagcctgtt ctggagtttc gagatcctca ttgtaaaatg gcagatcatc
     9721 gatttttaca aatacacttt cgtacccttc aggaagcaat ttcgcaaaag cttctgctac
     9781 ttttttgttg taagaatctt ttcttaaact accaataaaa aatccaattt tttttgtcat
     9841 acgatttttc ctccttcaaa ctatctataa taatcttaca aaagataagt aactggagca
     9901 aataaaaaca cttactgaca aaagctacat agaagataga ttacttattt ttaacaaaaa
     9961 agaagtctaa aatcttctat tttctaaaaa aaatcgaatt taatcaagct gtaaagaaaa
    10021 aaagctttac agggtaaaaa aaaactgtta cactacatct tgtgaataaa acaatggagg
    10081 tggaaataaa taatggcagt taaaatccgt ttaaaacgta tgggttctaa aaagagtccg
    10141 ttttaccgta tcgtcgtagc tgattcacgt tctcctcgtg atggacgttt catcgaaact
    10201 gtaggtactt acaatccttt gaaagaccct gcagaagtag ttttaaaaga agacttagtt
    10261 cttgactggt tatcaaaagg tgcacaacct tctgacactg tacgtaacat cctttcaaaa
    10321 gaaggcgtta tgcaaaaaca ccacgaagct aaattctcaa agaaataagg tgaccggata
    10381 tgaaagattt aagcgactta gtcttaacaa tcgttcgtcc gctagtcact tatcctgatc
    10441 aagtcaagtt agacgtcgta gagtcgaaag acttttacga gtacaatcta acagtggctc
    10501 ctgaagatat tggccgtatc attggaaaac aagggcgtgt tgctaaagca atccgcacaa
    10561 tcgtttacgg tgttcggatc aatgcaccga aaaaagtgcg tttgaatatc atcgatgata
    10621 aggaaaagta aataaacgtg ctgtactcga attttcgagt gcagcttttt tgtttttttt
    10681 attaattgaa gaaatgatta tttggcaaaa caagcaagaa agcgtatcct tataggagga
    10741 gggagtgaac agccaatgag aaagaaaatg ttatttattc catttgctct attgttaagc
    10801 gcttgtagtt cggttactca agaatcagac aatacacatc tatcaagcag tatatctgaa
    10861 actgttacca gtccagaaaa aagtagtacc aaaacggctt ccaccactga acaaacaatg
    10921 gctacctcaa ataatgagaa aaagactgct ttagaccagt tgaaagaaca acagccaaat
    10981 gttcccatgc ctctagatgt accagtctct tcaggctatc tcaatatcgc agcgacacat
    11041 acaaagcaag gttattctat tttatattac agaacagatc gtcccctcgg gttgaatgct
    11101 gacgaattga atcaagaaac gcctattgca acctatctat atcaatatgg gtttgcttct
    11161 agtcaagaaa caatccaagt tttgcagcca tttgagatcg acacaaatgg tcagcaagtg
    11221 gacttaggtt ctcgaatcac agggtatcag caaggtgcag caggttcaag ttttcttgaa
    11281 tggcaagaag gaaactggcg tattcgaatc cgtgggaata atatagaagg ccaagatccc
    11341 ttactattag ctaaagaaat cgtagcttat ttggaagaaa acagtctacc agcacctgaa
    11401 caatttggta aaattactgt tgatatgggt gatacgacga atcgagccgt agaagtaagc
    11461 tggcaagaac cgaaaaatgc ctatacgatc actcatcaag atcctatgtc tgcgttgaag
    11521 atggcagttt ctatgaagag gttgtgaaat cagcgcgctg atctgagccc atcatttaac
    11581 tccaagtcac aggaagtaat caaaaatagc acgccgcatt tttgcataat tttggcttaa
    11641 taccttaaaa gaaaactaga attgcctctt cacacatgct aaaataaaac agacaaaaaa
    11701 gaaatgggga tataagttga ctgaatactt gaatgtagga aaaatcgtaa acacacaagg
    11761 tatcaaaggc gaagtccgtg ttatctcaac aacggatttc ccagaagaac gttacaaaaa
    11821 aggaacggtg ctaacactat tccaagacgg aaaagcacct gtggaattaa cagtcaaaag
    11881 tcatcgcaaa cataaaaatt ttgacttatt gagttttgaa ggacatcctt ctatcaatga
    11941 tgtggaaaaa tatcgggatg gcatattaaa agtgtcaaaa gacaactctg tagatctagc
    12001 tgaaaatgaa ttctattacc atgagatcat cggtctgcat gtattagaag atggaactga
    12061 gttaggtaaa gtaaaagaaa tcttgtcacc aggtgccaat gatgtttggg tcgttcaacg
    12121 tccgaaaaaa gctgatatat tgcttccata tatcgcttct gtcgtcaaag aagtcgattt
    12181 agaagctgga gtggtccgtg tagaaattcc agaaggactg attgacgatg aagattgatg
    12241 tattgacttt atttccaaga atgtttgaag gtcctatggg ggaatccatc atcggtaagg
    12301 ctgtagataa aggattatta gatatcaata tctctaactt ccgcgattat tcagataaca
    12361 aacatcagac agtagatgat tatccatacg gcggtggagc aggtatgctg ctcaaagtcc
    12421 agcccatcta tgataacatc caagccattg aaaaagctgc accggatgtc aaaaaaagag
    12481 taattcttct tgacccagct ggtaaacgat tcgatcagaa aatggcagaa gaattttcac
    12541 aagaagaaca cttagtattc atttgtggtc attatgaggg atatgatgaa cgtatccgca
    12601 cattagtgac agatgaagtt tccttaggag attatgtcct tactggggga gaattaggtg
    12661 cgatggtcat gatcgatgca acagttcggc ttttgccaga tgtgttaggg aatcagactt
    12721 cagctcaaac ggattcttat tcaaccggtt tattggaaca tccccaatat actcgcccgg
    12781 cagaatataa agggatgaaa gtaccagaag tattgacaaa tggaaatcat aaattgattg
    12841 aagaatggca attaaaagaa tcactaagaa ggacctatca acgtcggcct gatcttttgg
    12901 aaacacttga atggacacct caaatgacga aatttttaga agaaatcaag aaagaagaac
    12961 aagaaaaaac agcagatgaa gccaagtgac tttttctaaa atcttcttta cagtaggttg
    13021 ataatatgtt agtattttat ggtgagtgca aaagcactta actattacga tattccgctg
    13081 tgagaaaagc tcataagaat atttggaata aggagaagaa aaccatgaat ccattaatcg
    13141 aagaattaac aaaagaacaa ttacgttctg acatcccagc gttccgccct ggtgacactg
    13201 tgcgtgttca cgcaaaagtt gttgaaggta ctcgtgaacg tatccagtta tttgaaggtg
    13261 ttgttatcaa acgccgcggt gctggaatca gcgaaactta tacagtacgt aaagtttcta
    13321 acggagtggg cgttgaacgt acattcccat tgcatacacc acgtgttgca aaaatcgaag
    13381 tagttcgcta cggtaaagta cgtcgtgcaa aattgtacta cctacgtgca ttacacggaa
    13441 aagctgctcg tatcaaagaa atcagaagat aaacacggaa aacttccttg gaaatctgaa
    13501 atttgtgaaa agtccttgta tatcaagggc tttttctttt ttctctatca cagttttaag
    13561 ccatttttgg ctgttttgga ccatttttca atcatattcc cttaaaaatt gtcctagatt
    13621 gtccgacatt gactatcagt gtcgtcaaaa tagggcaaaa tttagtagtc agcttgacga
    13681 caaatataat acgaaaaata ccaaaacatt taccgaattt agcaactttt gaacccaagt
    13741 ttctcaaagg gtcagctatt agcaaaaaag acaaaacatg tacttttcta ctaaaaagtt
    13801 gatgtgatag gcttctatct aaataactat taggagtttt tatcgtgaag caaaatgatg
    13861 gacgtatcat ttggaaaaat caaagtgagt taaaactgat tttaacaatt aatgaattca
    13921 tcgaaaaaca cggaattaca tctagccgtc aataccagaa aaagctatca gaaaatccaa
    13981 attctgcacc aagtatgtgg ttcattaaca aaaaatatgg atcatgggag aatttattga
    14041 ttagtatagg acgagaaaat actgggtatg gaaaatgggc tagaatgtca gaacaagaat
    14101 tattggaaat agtagaagcc tttattaagt gcgagaagat aacctctcaa cgaatgtacg
    14161 aacaaaaatc agtagggaag aatattcctt cacttagtac cattaaaaag atgttaggag
    14221 atatacgtcc actttttaaa gaaaaaaatg atggatctcg atttactgat ttcgaactgc
    14281 tgttagaact aaaaaatgaa ataatccgat taaaactaca ggatgattta tcaatgacaa
    14341 agtttcgaaa actagttcaa tccccaaaac taccatcagt tgatacaatt atgaaaagaa
    14401 cgaacaaaaa ttgggaggaa ttgatggcag agattggatt tgattatcga agaatcaaaa
    14461 tttataagca gagaaacaac ctatccaaga caaagaaaac taaatagtat cactctaaat
    14521 cagacgttca aaattaaaat ttggacgtct tttttattac ccaaaaacga aaggagattt
    14581 attttatgaa aaagccaaga tttaagaatt ggcgtttgct cgcaacactg agtctattat
    14641 gccaaacaat tggtggatcg cttggcccaa cgattgcctt tgctgatgaa attactcatc
    14701 cacaaacggt aactgtggaa ttggatttgg ctcaccagta tgctgtcgaa ggtacattta
    14761 gcgatggtcg tcccatgtca gaagttaccg ttccgcacta tgcagtttac aatggtgtga
    14821 agcaagatat tttctgtatt gagccagggg tgccgattta caatgagttc actcctggtt
    14881 atgagaaaaa tccattgcct gatatgtcgg agaaagcgaa attagtttcc gttttatgga
    14941 aggaagctgg tacggatgtg gatacacata ttgtggccca gaagatgatt tggcaagaag
    15001 ttaatggcta cacgcttcac tcaattaaac gttctgatgg tagtgcagta aatatcgcag
    15061 ccattgagtc aaaaatcaat caagccattg cggattatca aaagaaacca agcttccata
    15121 actccacagt gaaaaccgtg ttaggtcaat cgactactgt gacagatacg aacggcttga
    15181 atttatcgga gtttgatgaa gttgtcgaga atatcgcaaa tattgattat cgtgtgaacg
    15241 gcaatcaact agtgattact ccaaatgcca attcaaaaga gagtggtgaa ttaaccctaa
    15301 agaagtcagc taatacagga acaccggtag cttataaaat ggctggtcaa caaactttga
    15361 tggcgggggc aattgataag cccaatacct acacaatcaa aattgatgtg gaaactgagg
    15421 gttctttgaa gattaaaaaa gtcgataaag aaacaggaaa tgttgtaccg ggaaccgttt
    15481 tccatttaga ctttggaaaa acattacctg caaaagacgt gaccaccgat aaagaaggca
    15541 ttgcgacatt ggatgagatt cctcatggcg cgaaagtaac cattactgaa aaatcagtgc
    15601 cagctcctta tacgattgac actacaccaa tcaccgcaac cattaaatct ggtgagacta
    15661 tttctgtgac ttcaaaaaat actcgcgaaa aaggtcaaat cattttgaat aaaatggggg
    15721 tggaaacagg aactgatctt tggaacgaca aatactcatt agccggaaat acgtttgcca
    15781 ttcgcaaaga cagtccaacc ggtgaaattg tccaagaaat gaccacggat gaaaaaggtc
    15841 atgcggaaac accaaaagag attgccaatg cgttggaatt gggaacctat tatgtgaccg
    15901 aaaccaaagc tagtaatggc tttgtgaata cctttaaacc agtaaaagtc gaattgaact
    15961 atgtcaatca aaccgtggct cttgttacca gtaacgtaaa agggcaaaac caagaaatca
    16021 ctggtgaaac cactttgaca aaagaagaca aagataccgg taatgaaact caaggtaaag
    16081 ctgagtttaa aggagctgaa tatactctct ttactgcaaa agatggtcaa gcggtcaaat
    16141 ggagtgaggc ttttaaacca gagttagtga agggaacgaa agcttctgat gaaacggtga
    16201 ctttgacttt agatgaaaag aatcaagttg ctgttaaaca cttagcgatt aatgagtatt
    16261 actggcaaga aaccaaagca cctgaaggat ataccttgga tgaaacaaag taccctgttt
    16321 ccatcaaaaa ggtggatgat aacgaaaaaa atgccgtgat tacccgagat gttacggcaa
    16381 aagaacaagt cattcgcttt ggctttgatt tctttaaatt tgctggatca gctgctggga
    16441 ctgccgaaac tggcttcaat gatctgacct ttaaagtatc gccattggaa ggaaccagtg
    16501 agattacagg tgccgaagat gaagcaatta cagcttataa cgagcaacta ggttttgatg
    16561 gctatggcaa gtttgaaaat cttccttatg gggattattt acttgaagaa gtagaggctc
    16621 cagaaggatt tcaaaaaatt acgccattag aaatccgttc tacttttaaa gaaaataaag
    16681 cggattacac taagagtgaa tacattttta cgattaccga aaaaggacaa aaacaaccaa
    16741 ttaaaacggt gaccgttcct tacgagaaac tgacgaataa agcattttct gttagcttga
    16801 atcgtttgat gctctatgat ttacctgaag aagaagatag cttaacttct cttgggactt
    16861 ggaaagacgg aggcaaagaa ttgacagacc ttgattctac cgagctagtt gataaattga
    16921 gctataactt gcatgaaatc aaagaagact ggtatgtggt agcgcaagcc attgatgtgg
    16981 aagcgacaaa agctgcccaa gaaaaagatg aaaaagccaa accagtggta attgccgaaa
    17041 caaccgcaac gttggcgaat aaagagaaaa caggaacttg gaaaattttg cataaattaa
    17101 ccgcagaaca agttttggat aaaaccatcg tcttattcaa ctatgtgtat gaaaacaaga
    17161 aaccctatga agcaggtgat gatccagtag cgaaagatgc tagcttgaac aatcaagccc
    17221 aaactgtcaa ttgtacggtg gaacgccatg tttccatcca aacaaaagcc cacctagaag
    17281 atggttcgca aacctttact catggggatg tggtggatat gttcgatgat gtgtcgatta
    17341 cccatgatgt actggatggc tcaaaagaag cttttgaaac aattctgtat gcattacttc
    17401 cggataatac gaccaaagaa atttggaaat ctggcaaaat tgattatgaa gtgaatgaca
    17461 aagaattcac taaaaccgta cttgcggaaa aagtggacac aagtaaatat ccagaaggta
    17521 caagttttac cttcaaagaa attaactatg gcaaagacgg aaacatcaat gggaaacaca
    17581 atgaggatct aaaagaaaaa actcaaactt taacacctaa aaaagttccg acaacaccaa
    17641 gtgcaccaga acaaccggaa ataccaactg ttccaagtga ctctcaagaa tctagtccta
    17701 cagtaaagac attcccacaa acaggggaga aaaattctaa tgttctgctg tttattgggt
    17761 ttaccttgat ctttgcgact gctgggtatt atttctggaa tcgccgaaac taaggtgatg
    17821 tgatgaaaca actaaatagg aaaaaccaac gtgcgcgacc gcctcctaaa aaaagtggtc
    17881 gcgctatttt tgtatccaaa actaaaaatg aaaagaggaa aagaagatgg aattgaaatt
    17941 tgttgtgcca gatatggccg aaacctttgg aaagataagg tatgccggcg aaggcgaagt
    18001 tttaactgaa ggatatgggc ggaatactac agtaattggt cgtagttatc atttgtattc
    18061 cagtaagcaa cgagccgatg atattgaagt ggtggtagct gcggaagccg gcgaaaagga
    18121 ttttgaccaa gatcaaccac taaaagccgt gaatccccat ttggttgcca aaggctatga
    18181 gattgagaat cgtgggttta ccgactacgt gttgtatgtc gatgatttag tgaaagcata
    18241 ggaggaaaag aagatgagat taacagaagg tattgttgta gattcaggac taacgtttgg
    18301 gaaattacga ttttccgcat tacgccgaga agtacggaag caaaatgagg atggaacggt
    18361 tagtaacgag gtaaaagaac ggacttataa tttgaaatcc tctgcgcaag gtcgaatgat
    18421 ccaagttagt atcccagcaa atgtaccctt acgcgagttt gcctatgacg cagaggtaga
    18481 gttggtcaat ccaatcatgg atacggtcgc caattatgtt ttccgagaag gaactactgt
    18541 caattggttc attaaggccg atgatttagt cttgaaacga caaccagatc agggaaattc
    18601 tacaaaccaa aatgaaggaa agaaataggt gaagcgtatg gaaattaatg ttgaacatat
    18661 tttagattgt ctcgatcaat atggaaaagg tgagctaacg gaggaacaac tcactaaagc
    18721 attaacctat gatgaaaaaa tgtttctgat tatgcatcaa gggttactgg aagtaggtaa
    18781 cgatgtcgaa gaagattttg atgtactgaa ttggttaggg gaagaagagt ccttctttat
    18841 ggttatcgaa gtaaatgaaa gtctatgtcg agaagccgaa accgtattgg aagaaattgg
    18901 tgtggaaatg ccggatgcca ttgaagtttt tttaaagcaa ctagtggaaa cgaaacaact
    18961 ccctatagca gtaaatgact agcataactg cttgaaattg gatcaatgaa atcctatgaa
    19021 gcttttttcg attggaggtg gaaaccataa aaatgtacaa agggcatcgt atacgggcag
    19081 gagatcagca cttggtttat cactttgttc ttggctggct actcgctctg ttcatcggtt
    19141 ggatgagcgt cttttatttt caagagctta gacaatttga tatttctaag ctatcacttt
    19201 ctactataga aatcgttcgt tctataaaag atttaatcta tttgctagga agtctcgttc
    19261 tttcaggaag cacgatgttg ctttatatac acttttttca ggatcattgg cgcagtttgt
    19321 ggcatcgaca aaagctagcc cggatgattc tagaaaatca ttggtacgaa gtaaaacaaa
    19381 ctcagagtga aggatttttc aaagacctca atagtagtcg aaccaaagag acaatcagtt
    19441 acttccccaa aatctattac cgtatgaagg atggtttact ttctattcgc gttcaaattt
    19501 cactgggaaa atatcaagat cagcttttaa agctggaaaa gaagttagaa agtggtctat
    19561 attgtgaact agtagaaaag gaactcaaag actcctatgt ggagtacact ttactgtatg
    19621 atataattgc caatcgaatt gggatagacg aagtagtggc agaaagtggg gctttgcgat
    19681 tgatgaaaaa tcaagtatgg gcttatgatt ctttacctca tatgttaatc gctggcggca
    19741 caggtggtgg gaagacttac tttttactca ctatcatcga ggctttatta aaatctgatg
    19801 ccgagctttt tgttcttgat cccaaaaatg cggacttagc cgatttaggt acggtaatgc
    19861 ctcatgtcta ttcccaaaag gaggaaattt ctgcttgtgt ggaagatttc tatgagcgca
    19921 tgatgactcg tagcaaggca atgaaagaaa tgcccaacta caaaacagga gagaattatg
    19981 cgtttcttgg acttccacca aactttttaa tctttgatga atacgtggtt tatatggaaa
    20041 tgttaacgac gaaggaaagt gcggtgattt tgaataagct caaacaaatc gtgatgttag
    20101 gtcgtcaatc tggtttcttt ctgattctag cttgtcaaag accggatgcg aaatatttag
    20161 gagacgggat tcgcgatcaa tttaatttcc gggtggcttt gggtcgtatg agtgaactgg
    20221 gatattccat gatgtttggc gaggttgata aaaaattctt tatgaagcgt atcaaaggtc
    20281 gaggctatgt agatacggga gggagtgtga ttagtgagtt ttatacgcca cttgtaccaa
    20341 aaggatatga tttcttaagg gaaattagcg acattggtgg attaaacgtt aatacggaag
    20401 gataaaataa tagtatgtag cctaggagtg tcaagaatcc tgggcttttt ttacgaggtg
    20461 atttatgaca tttttagatt tattcgctgg gattggtggc ttttgcttag gtatggaaca
    20521 agcgggtcac cagtgtatcg gcttttgtga aattgatgat tttgctcgcc agagttataa
    20581 ggcaatccat gatacaagta aggaggtgga aatgcatgac atcacaagtg tatcagacga
    20641 gtttattcaa tctctcggac cagtggatat cctttgcggt ggatttccgt gccaagcttt
    20701 ttcaattgcg ggaaagcggc aaggattttc cgatactcga ggtactttat tctttgaaat
    20761 cgctcggttc gccgctattc tccaacctaa gtttttattc cttgagaacg tccggggatt
    20821 actcaatcac gaaggagggg ctacgttcga gacgatcctc cgaacgctgg atggattggg
    20881 gtatgatgtg gaatggcaag tgcttaactc aaaggcctac gttccccaaa accgtgagcg
    20941 gatcttcctt atcggacatt ctcgagacgc atgtaccgaa caagtatttc ctatcattgg
    21001 atcgtctcca acatctgatc aaaacatcag aaacttatta aatatcaacc cttccaatcg
    21061 aggaatgggg ggacaagtct atgggtcaga tgacgtagcg cctaccttga ccggtgatga
    21121 aggaatcaaa atcgcattgc cggtagatga tggaatttct gtagcgggta tgttactggg
    21181 aaattttgaa caaggcaatc gggtttatga gataactgga acagcgccta ctttgtcaac
    21241 gaaacaaggc ggaacgaaga tcatgcttcg gaaaaacgaa acagaatatc aagaggtgaa
    21301 gccagggaac agtgtgaacc tggcttttcc taattccaca agtcgtcgag gccgtctggg
    21361 aaaacaaagt gtgcatacct tattaacagg agaccaacaa gcagtcgtca cggatcagta
    21421 tcaaattcga aagttaacac ctagggagtg ctggcggctt cagggctttc cggactgggc
    21481 ttttgatcga gcttctcaag tcaattcaga tagtcagttg tataagcagg ctggaaattc
    21541 tgtaacagtt ccggtcattt ttgatattgc tagaagatta aaggaggtaa aaacagatga
    21601 tttatgatga gttgattggg gaatctactg ggtgattggc aagattcagt cagatccgga
    21661 attggaagaa gaactgtacc ggctcaattt tgatattcgc aaaaacgggg tgaaagtccc
    21721 tgatgatccg tatgtaattg atgaggaaac ggatgctcga atggagctga atcaagtcat
    21781 cagtgaattg gaacgaattg cggactttgc taaagaacct gatatccgcc aatacttgtt
    21841 tgagataaaa gcagagttgg aaattgaggg tattaccgcg gagtaacggc caaataaacc
    21901 actgataggc actgaccgcg ggggatttgc gaagcagaaa tcctccgtgg tgctgtgcct
    21961 gtttatggac ggcgttagcc ggccatgatg tctcaccccc cgtatctaac aggggggtac
    22021 aaaaacacaa aaaataagca agcaacgata aggaatggct gtcctatcaa ggataataag
    22081 caatttgtgt agatgttaac tgatttgaaa aagttaacac cttaaatttg gaggtgagaa
    22141 cttggcacaa aggaatttag attatcggct attaaaagac cggcgtaatg aatatggcgt
    22201 ttcacaaaat aaattagcta cgacttgtgg acttagtcgc ccgtacttaa atcagataga
    22261 aaatggtggc gtaaccgcat cgacaaaaac catgaggaaa atttttgacc aactggaaag
    22321 tttcaatccc gagttacctt taacgttact gtttgactat gtaaggattc gctttcccac
    22381 aacggatgcg aggaaaatca ttcaagagat tctccatttg aaatttgatt atatgctcca
    22441 cgaagattac gccttttact cctatcaaga acaatatgtt atgggagata ttgtggtgat
    22501 gttgtcacat gaagaagata aaggcgtcct tttagaatta aagggtcgtg gttgtcggca
    22561 gtttgaaact tttttactcg cccaaaagcg tagctggtat gactttttcg aagattgtct
    22621 aaaagccggt ggcgtgatga aacgcttaga cctggcaatc aatgatcgag ttggcctgtt
    22681 agatattcct gatttaacga aaaaatgtca gaaggaagaa tgtatctcct tgtttcgtac
    22741 cttcaaaagc tatcgttccg gggaactgtt gaaacctgat gataaagatg gtatgggcaa
    22801 tactttgtat attggcagtc ttaagagtga ggtctatttc tgtttgtacg aaaaagacta
    22861 tgagcaatat atcaagttag ggattccttt agaccagacc gaaacgaaaa atcgttttga
    22921 aatccgactg aaaaatgatc gagcttatca tgcaattcaa gatttgttaa aaggtcgcag
    22981 tattgaaagt accacatttt ccattattaa ccggtacttg cgatttgcgg ataaggtgga
    23041 aggcaaaagg cgaactaact ggcccttgaa tgaacaatgg gggcgcttca ttggacggaa
    23101 tcagaaggaa attcaattaa cttctgaacc gaagccttat accattgaac gaacgttgaa
    23161 ctggcttgga cgacaagtcg cccctacgtg gaagatggcc aaggagttgg atcggttgaa
    23221 tcagacaacg tacattcagg atatggtaaa taatactcga ctatcagacc ggcacaaaaa
    23281 gattttggag caacaaagta tggcaattga aaatttgatt atatgaaaag aggaatcgtg
    23341 atggaaattg tgaaagatat tttattggtg tttggtggca gtatgcttgg tgttactgtg
    23401 atgtgcttga tgcatgcaag tgcagcggcg gaccgagcaa tggaaaagaa aggaaagtga
    23461 tgaaatgaat ttcggtcaaa attt
//
LOCUS       DADGHT010000040        23358 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.040, whole genome shotgun sequence.
ACCESSION   DADGHT010000040 DADGHT010000000
VERSION     DADGHT010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.040"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            138..995
                     /locus_tag="JX887_001424"
     CDS             138..995
                     /locus_tag="JX887_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAX1257420.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1110..2030
                     /gene="pstC"
                     /locus_tag="JX887_001425"
     CDS             1110..2030
                     /gene="pstC"
                     /locus_tag="JX887_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAX1257421.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2030..2914
                     /gene="pstA"
                     /locus_tag="JX887_001426"
     CDS             2030..2914
                     /gene="pstA"
                     /locus_tag="JX887_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAX1257422.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2929..3735
                     /gene="pstB"
                     /locus_tag="JX887_001427"
     CDS             2929..3735
                     /gene="pstB"
                     /locus_tag="JX887_001427"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAX1257423.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3751..4509
                     /locus_tag="JX887_001428"
     CDS             3751..4509
                     /locus_tag="JX887_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAX1257424.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4522..5199
                     /gene="phoU"
                     /locus_tag="JX887_001429"
     CDS             4522..5199
                     /gene="phoU"
                     /locus_tag="JX887_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAX1257425.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5437..5736
                     /locus_tag="JX887_001430"
     CDS             5437..5736
                     /locus_tag="JX887_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257426.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5762..6469
                     /locus_tag="JX887_001431"
     CDS             5762..6469
                     /locus_tag="JX887_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAX1257427.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6466..7233
                     /locus_tag="JX887_001432"
     CDS             6466..7233
                     /locus_tag="JX887_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAX1257428.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7333..8901
                     /gene="liaX"
                     /locus_tag="JX887_001433"
     CDS             7333..8901
                     /gene="liaX"
                     /locus_tag="JX887_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAX1257429.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9201..9518
                     /locus_tag="JX887_001434"
     CDS             9201..9518
                     /locus_tag="JX887_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAX1257430.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            9518..9868
                     /locus_tag="JX887_001435"
     CDS             9518..9868
                     /locus_tag="JX887_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAX1257431.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10035..10973
                     /locus_tag="JX887_001436"
     CDS             10035..10973
                     /locus_tag="JX887_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAX1257432.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10988..11818
                     /locus_tag="JX887_001437"
     CDS             10988..11818
                     /locus_tag="JX887_001437"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAX1257433.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11862..12887
                     /locus_tag="JX887_001438"
     CDS             11862..12887
                     /locus_tag="JX887_001438"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAX1257434.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12902..13840
                     /gene="galU"
                     /locus_tag="JX887_001439"
     CDS             12902..13840
                     /gene="galU"
                     /locus_tag="JX887_001439"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAX1257435.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13965..14405
                     /locus_tag="JX887_001440"
     CDS             13965..14405
                     /locus_tag="JX887_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAX1257436.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14408..15010
                     /locus_tag="JX887_001441"
     CDS             14408..15010
                     /locus_tag="JX887_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAX1257437.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15078..16184)
                     /locus_tag="JX887_001442"
     CDS             complement(15078..16184)
                     /locus_tag="JX887_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAX1257438.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16394..17395
                     /gene="ccpA"
                     /locus_tag="JX887_001443"
     CDS             16394..17395
                     /gene="ccpA"
                     /locus_tag="JX887_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAX1257439.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17731..20076)
                     /locus_tag="JX887_001444"
     CDS             complement(17731..20076)
                     /locus_tag="JX887_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAX1257440.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20355..21257
                     /locus_tag="JX887_001445"
     CDS             20355..21257
                     /locus_tag="JX887_001445"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAX1257441.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21470..23245
                     /locus_tag="JX887_001446"
     CDS             21470..23245
                     /locus_tag="JX887_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAX1257442.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
BASE COUNT         7443 a         4142 c         4926 g         6847 t
ORIGIN      
        1 tagcatagaa acttttaatg agatagtttt ttttacaatt atgagaattt attttgttat
       61 ttaatgattt tgattcgttt tcatcaagta atgaaaatga taaaataaac atactttagg
      121 attaaaggag atttctaatg aaaaaactta aattattctt accaataata ggattagcca
      181 ttcttttatc aggctgttca aagtggattg atcgaggaga atccattacg gctgttggct
      241 cttctgcttt acagccttta gtagaaacag ttgctgaaac ttaccagaca gaaaatcctg
      301 gaaaattcat caatgtacaa gggggcggaa gcggaactgg tttgtctcaa gtacagtcag
      361 gagcagtcga catcggaaac tctgatttgt ttgcggaaga aaaatcgggg atcgatgcct
      421 cagcattagt cgatcatcga gtagcagttg ttgggatcac tcctattgtg aacaaggata
      481 ttggcgtaaa agacatcagt atggaaaacc tgaaaaaact atttacaggc gagatcaaaa
      541 actggagtga agtcggtgga aaagatcagc cagtagttat attgaaccgc gcttcaggaa
      601 gcggaacccg tagcacgttt gaaaaatggg tattggacgg agaaacagct gttcaggcac
      661 aagaacaaga ttcaagcgga atggtgcgcc agatcgttgc cgacacaccc ggtgcaatca
      721 gctatgttgc tttttcttat gtttccgatg atgtagatac gttgaatgtt aacggtgtag
      781 aaccgacaga tgaaaatgtg acaacgaaca aatggacgat ttgggcatat gagcatatgt
      841 acacaagaga tcatccaaaa aaactgacaa aagaattttt agactatatc ttatctgatg
      901 aagtacaaga taacatcgtt ggagaactag gttatatccc tgtttctcat atgaaagtcg
      961 aacgtgattg gcaaggaaat atcgttaaag agtaatcttt acacaaaatt tacaaactta
     1021 gctaaacttt tacatgttat taaaaccaaa ttgatgttca atttgtacac tgagtgagta
     1081 tgttaaacct gattaagggg gagtcatctg tggaagatgt gaaaaaagta ttattaacaa
     1141 aatcaaaacg ttcaaaaatg gaacagcgtg gaaaattcat cagtttttta tgtatcgcgc
     1201 tgatcgtgtt ggttgtatta tctatttttt attttgtagc tagtaaagga ttggccacct
     1261 tttttactga taagatcaat gtatttgatt ttctgtttgg tacagattgg aatccaagcc
     1321 aaatcggagc aaatgggaaa ccaatggtag gggcattgcc tatgatcaca ggttcgttta
     1381 ttgtgacctt tttatctgct atcgttgcca cgccatttgc cattggtgca gcagtattca
     1441 tgacggagat ctctcctaaa aacggaacga agatcttaca gccggtcatc gagctgcttg
     1501 taggtattcc ttctgtcgtt tatggtttta tcggtttatc agttatcgtg ccttttgtca
     1561 gaagtatttt tggcgggaca gggtttggta tcttagctgg tacatttgtg ttgttcgtta
     1621 tgatcttgcc gactgtcaca acgatgactg ttgatgcatt aaaggcagtg ccacggcact
     1681 atcgggaagc ttcattagcg cttggtgcca caagatggca aacaatctac aaagtcgtgc
     1741 tacgagcagc cgtgcccggg attttaacag cagtcgtttt tggtatggct cgtgcgtttg
     1801 gtgaagcctt agctatccaa atggtcatcg gtaatgcagc attgatgcca acaggactta
     1861 ctactcctgc ttctacattg acgtccatct taacaatggg aatcggaaat acaatcatgg
     1921 gaacagttga aaataatgtg ttatggtcat tagcgctgat cttgctattg atgtcattat
     1981 tctttaatat cgtgatccgt atgattggga agaaaggaga gctgaaataa tgaacgcaaa
     2041 acgctcagat aaaattgcta caggtgtttt atatatagtt tcggggatca tcgtattgat
     2101 tttagcagct ttactacttt atatcttagt tcggggaata ccgcatattt catggtcctt
     2161 cttgaccgaa ccttccaaag cctaccaaga aggcggtgga atcgggatcc agctatttaa
     2221 ctcgatttat ttgcttttga tcacgatgat catcagtttt cctatttctt taggtgcggg
     2281 tatctatctt tcagaatatg ctggaaaaaa ctggctaaca gatgtgattc gcacgtcgat
     2341 tgaaatcttg agctcgttgc cttctgtcgt tgtcggttta ttcggtttct tggttttcgt
     2401 tattcaattc cagtatggtt tctcgattat ttctggtgca ttggctttga ctgtattcaa
     2461 cttgcctctt ttgactagaa cagttgagga gtctttacaa gcggtccatt acacacaacg
     2521 agaagcagga ttggccttag gtttgtcacg ctgggaaaca gtgataaaag tggtggttcc
     2581 agaagcgaca ccagggattt tgactggtgt gatcctaagt tctggaagaa tttttggtga
     2641 agcagctgca ttgatctata cggctggaca aagtgcacct gcgttagatt ttacgaactg
     2701 gaatccatta agtgtttcaa gcccgatcag cattttccgt caagctgaaa cattagctgt
     2761 ccatatttgg aagatcaata cagaaggcac gatgcctgat ggtgtttctg tttcggctgg
     2821 cgcttctgcc gtgttgatca ttgctgtttt actgttcaac ttcggcgctc gtgcgattgg
     2881 caaacgatta taccgaaaaa tgacttcagc ctaaggagaa gaagcaaaat gaaaaaatat
     2941 aactggaatg aaacaaatgt catcaccatg ccaaaagaga aagaagtagc actatatacg
     3001 gatgatctac atgtctggta tggcgacaat gaagcaatca aaggagtgga tctggaattt
     3061 gaaaaaaata agatcactgc actgattggt ccttccggct gcggaaaatc tacgtatctt
     3121 cgttcgttga atcgaatgaa tgatgggatc gctaatacga aaatcactgg gaaaatcatg
     3181 tatcaaggcg tagatattaa tgcgcctcaa gtggatgttt atgagatgcg caaacggatt
     3241 ggcatggttt ttcaacgtcc taatccgttc agcaagtcga tttatgacaa tattacattt
     3301 gctttgaaac agcacggcga aaaaaacaaa aagaaattag atgaaatcgt tgaaacaagc
     3361 ttgaaacaag ctgccttgtg ggaccaagta aaagacagct tggacaaaag tgccttggct
     3421 ttatctggcg ggcaacagca acgtttatgt attgctcgtg cgatcgcgat gaaacctgat
     3481 atcttgctgc tagacgagcc ggcaagtgct ttggacccta tttcgacagg aacggttgaa
     3541 gaaacacttg taaacttgaa agaagactat acgatcatca tcgtgacgca taacatgcaa
     3601 caagcagctc gtatcagcga ctatactgcc tttttctatc taggaaaagt aatggaatat
     3661 gacaaaacta acaagatatt taccagacca aaaattcagg caaccgaaga ttatgtgtcc
     3721 ggtcattttg gttaagacgg aggcctcaac atgacaaaag aaattatttc atctaaagat
     3781 cttcatctgt attatggaaa gaaagaagca ctaaaaggga tcaatctaag tttcaatcaa
     3841 ggggaaatca ctgcgatgat cggtccttct ggttgcggga aatccactta tctgcgttct
     3901 ttgaaccgga tgaatgacct gattccgaat gtaacgatca ccggaagtgt tttatataaa
     3961 gacaaagaca tctatggtcc aaaaacagat gttgttgaac taagaaaaga aatcggcatg
     4021 gtattccagc agccaaaccc atttcctttt tctatctatg aaaatgtcat ctatggattg
     4081 aaattaaaag gggaaaaaga taaaaaagtc cttgatcaag tagttgaaga aagcctgaag
     4141 gcagcgtctg tttgggatga tgtgaaagac aaattgcata aaagtgcttt atctttatcc
     4201 ggtgggcagc agcagcgtgt atgtatcgca cgtgttttgg cagttaatcc ggaaatcatc
     4261 ttattggatg aaccaacaag tgcgcttgat cctgtttcta ctgggaaaat cgaaagtatg
     4321 ctgttagaat taagagagcg gtatacgatg atcatcgtga cccataatat gtctcaagct
     4381 tcacgtattt cagataagac ggcattcttt ttagatggtc acttgatcga atacaacgat
     4441 acgaagaaga tattcatgaa tccagaaaaa caagagacag aagattatat ttcaggtcga
     4501 tttggataag gaggaaacgg aatgctacgt acacaatttg aagaagaatt gctgaatctc
     4561 cataatcagt tctacgaaat ggggatgatg gtgagcagcg ccgtgcacaa gtcagttcgt
     4621 gcatacatca aacacgataa aatcttagcc caagaagtta tcgaaaacga tataaatatc
     4681 aataacatgg aaacacgctt ggagaagaaa agttttgaaa tgatcgcatt gcaacagcca
     4741 gttacaactg atttgcgtat gatcattacg gtcatgaaag ctagctcgga tttagaacgt
     4801 atggccgatc atgcggtgtc tgttgctaaa tccacgattc gcgtaaaagg gcagacgaga
     4861 ataccggaaa tcgaaaaaga gatctccgat atgtccgatt atgtgaaaaa aatggtggac
     4921 aacgtcctag ttgcttatgt caaaacagac gaaaaagacg cacgtacgat cgccaatatg
     4981 gatcaaagag tcaatgacta tttcaatcga atctataatg caacaatcaa aaatatgcag
     5041 gaaaatcctg agacagtcat cagtggaaca gactacttga atgttgccag ttatctagaa
     5101 cggatcggag actatgtgac aaacatctgt gaatggatcg tctacttggc tacagggaaa
     5161 atcactgagt taaatacgaa ccacaatgag attttctaaa ctgaagctgt gattatgccg
     5221 tttgtttagg aaaagaggtt gtgaaatcag cggttgtgaa aaagctgttc tgcatcaagt
     5281 aataagaaca gtcaaacaaa aaatagctcc tcatattttt cgtttggctg gacttattac
     5341 cgcagatgca agcttttgaa caccgtttat tcgggaaagg gtttgtgaca aaacatgtca
     5401 caaacccttt tcatcatttc atagaaagga taaagaatgc aaaaaaaaat tagcatcatc
     5461 actatatttt ttatttgtgt gcttacttca tgggttattc agcatcaagc tgctttatat
     5521 gaagtacctg tcatcgagat cgaaaaagta cgaataaaag aggatcatca attgattaca
     5581 ggaagactga tgaacacgga tcaaaaagga gaatcgattt atttatcggt tccttatcaa
     5641 aaaaatcaaa tagaaacagc aaatataaaa gcgagacaaa tgtatctagt ccaaatgcat
     5701 ggagatgaat ggcagctagt agcaaaaaaa aaatgatggc tggcttttct tcttcacaag
     5761 tatctccatt ggcgccatgt tgcttattgg cggaaaacag ggtctatttg ctttaggaag
     5821 tctcatcatc aatatcgttt tacttttact tttgttgctc atctttacta aaacagaagg
     5881 gatttctcta ttaaatatat ctatcctgtt cgtcgttata gggatgatta ttagcatatt
     5941 ggctttagat ggatggaata gaagcagtat aatcaaaatt tcagctgcag ttacgagtgt
     6001 ttttttagca ttttttattt gtcttttgac aatgaatcat tggaaagacc aaggactgcg
     6061 ctatgaggaa ctgaattatc tgacacgacc gtatcgttct gtttttcttt ctagcgtact
     6121 gattggaaca gctggaggaa cactcgatac cgttatcaca gtcattgcga cattagaaga
     6181 attgactaag cgacaaccag aaataacagc gaaacagtta tggctttcag gaaggcaagt
     6241 gggtcgagat gtgattggct cgatgaccaa tatccttttg ttcgtctata tcagtgggtc
     6301 agttccatcg cttcttttat atttaggaaa tcaatggtcg ttcaaagaaa cgatagaaca
     6361 gcatttatca ttggaatttt tacgcgtcat tgctggcagc ttaggaatag tattatcgat
     6421 ccctatctcg gtcctctttt ttctgactgt aaggaggctg aaacgatgaa tgtacttatt
     6481 atacttgttg ggattttagc aatcagcgtg ctacttattg gcggtacgca aggtatgtat
     6541 attcttttag gcttattcat caatttaggg atctttttcc tgttgttatt cggttatcat
     6601 cagaagtggc cgatactggc attgtcggtc ataggatttt tattgattgc tgtggttatc
     6661 ttatttttta tcaacggtta taatctaaaa atgcgtgcag cttttgtgag tatactgatc
     6721 tttttatttt gtttcctact attgcttcct atcactgatt ttttagcgat ccaaggtttt
     6781 acatcggtag aactagaaga attatctggc ttagataaga ctttagcgat tgattttaga
     6841 ttacttacga gatcgttgct tctgattagt cttagtggtg ctgttttaga tgctagtgta
     6901 gcaatttcta gtgggacatt cgaagtatat caggcaaatc cgcaattatc tttttaccaa
     6961 ttgcgccatt ctagtttcgc tattgctaaa aaaatattgg cgtcaacagt aatgacactt
     7021 ctttttgcat tcatgggaag ttctttagcg ttgatcctct ggtttattga tttagacatt
     7081 ccttttcagc aagtgatcaa tgaaaaatca tttgttctag aatatacgat ggctattctt
     7141 accacattgt ctgcactact tgttcttcct ttaacctgcg tgactacagc atatctcttt
     7201 acaaaaaaga aagaacaact caagatggag taaaagttac aacttaagtc ctatgacatt
     7261 tttactgaat cagtgcataa tatggatgta aggaaaagct tgcaaacaat tttgcttaag
     7321 gaggcaattt ccatgaaaga aagagaacgt attttagatt tagtgaaaaa aggaatcctt
     7381 tcgactgaag aaggcttaga tttattagaa agcatggcaa ctgaaaaaga cgaaaagcaa
     7441 ataaaaaaag aagcagacaa ggtaactgct agtcataaag aaaaagatca ggcaagtcaa
     7501 ttgatcgata aacttgaaaa cggcgaagaa gaaatttctg agccagttga tccaaaggaa
     7561 agagaaaggc aagatcaaga aaacttagaa aagatcttag atgaactagc aactgaagcg
     7621 aataaaactt cggcgcgtct agatgaagta aatgctcaat tcgctgacaa taaggcagca
     7681 cgcaatgaga aacaggaagc attgatgcag ctgaatacaa aagaagaatt aggcgagttg
     7741 acagaagaag aattagcaca gcgtcagacg ttagaagcag aaatcaaaga attagaagct
     7801 agtggcgata cactgttaga agaacaattg aaattagaag cagaattaaa agatatccgt
     7861 aagaatcaat ggtctgagaa aaaagaaacg tttactgata agtttgaatt gccagatgat
     7921 tggaaagatc aagcaacaga tacactgaat caagtaggcg aaaaaatgtc agaagctgga
     7981 tcacagttag gcaaattctt gaagaaaaca ttccaaactg tttcagaaac agtgaatgac
     8041 aacatggaat ggaaagatgt cagcttacgt gtccctggga ttgcgacaac gaaatttgag
     8101 catgaatttt actatgaagc tcctgcagca agtatccttg atatcaaggc agcaaacgga
     8161 aacgtgacgt taaaaacgtg ggacagcaac gatgtgaaag ttgaagctaa gatcaaactt
     8221 tacggaaaaa tgggtgctga accatttgaa gcattctctg aacggagcca gattgaggtt
     8281 aatgaagatc atatctcctt ccaaattcca aataaacgtg tgcgtgcaga ccttgttttc
     8341 tacttaccta aacgagtata cgaccacgca gctattaaac ttctaaatgg caacatcatg
     8401 attgaaacat tggaagctaa agatatttat acaaaatcta cgaatggtaa catcatcgtg
     8461 gaccaattaa ctgcaacgat gctggaagta gaaggtgtaa acggcaatat cgatattcga
     8521 aacgggaaca tcttagattc tattatcgaa acagtaaatg gtacagtgac atttggtgcg
     8581 acagcagaaa acctttctgt gtctttggta aatggtgatg tacgtcttac gattaaagaa
     8641 gataatttga aaaaagtaga agcaagttca gtgaacggaa atgtcaaagt cgctttacca
     8701 gatggcatcg gtttggaagg acatgctaaa acaagtcttg gaagtatcaa cagccgtctg
     8761 tccaattacg aagtagttcg tgagaaaaaa gaacggacaa accaaatgtt gcaattccgt
     8821 cgtgtttcag atggtgaaat cacgcaagtg caactttcaa cgacaacagg aagtatctat
     8881 ttaaaagata cagataaata aagaggttgt gaaagagatg ttcagccttg agcaataaga
     8941 agcgattttg taaaatagct tcccctattt tacaaaattg tgccttattg ccgataggct
     9001 atctcttgaa caccgtttac caagagatta tgaacctgcc aattatcgcc gagtcacaag
     9061 gaataatttc agaaaaagct cgtcacgttt tatgaatatg gtaatttgtg accgagaatt
     9121 ttgcagaaag acaccgatta agaagaaggt tgtcacaacg attttcttca tttaaaatag
     9181 tagaacagag gtgagacatg atgaaaaaaa agttgacaaa atccaataaa aatgttgttt
     9241 tgacagggac tttagcagga ataggagaat acatcgggat tgatccgact gttatccgtg
     9301 tgctttatgt attcctgagc ttagttgctt ttggaagtcc aatcatttta tacattttat
     9361 tagctttgat tatcccatct gcgcgttctg cacgaacaaa ctatggacat aacaatgcat
     9421 attatgaaaa aaacaattat cgtgaacaaa ctcgtgaaca aacaaaaaaa cgcaaagaag
     9481 cggaaaaaat cgatgatgac gaatggagtg acttttaatg tcgtactttc aacgtatttt
     9541 agttaatacg ttaacattca tatcattggc tgttcttttt cctgcgatgg tccatgtgag
     9601 cagtatttgg acggccgttc ttgccagctt cgtattgtct gtgttgaata tgtttgtcaa
     9661 accgattttg acgatactgt ccctgccctt tacattagtc acattgggat tgtttacgtt
     9721 tgttatcaat gcagcgattc ttaaaatgac ctcctttttt gtgggagcag aacattttag
     9781 tttttcttca ttcggtgcag cgttgttagt agctatcttg atgtcgcttg tcaatgtaat
     9841 tgtcagtgaa cataacagta gaaaataaaa gaaagctgtg ccgaactatc ggcgcagttt
     9901 ttttatttag aatcaggaat gcgttttcta ttacattggt aattaaataa aaacgttttt
     9961 tttaattggt agtacttttg gctagacaat gataaaatga tagagaacac tctaatagaa
    10021 atgaggtagc atgaatgtca gaagttgtaa aagttagcca attagtgaaa aaattatctt
    10081 tggaaatcgt gacaggcgac gagaaaagct tagaccgtgt catcgtaact ggggacatct
    10141 cacgcccagg actagagttg actggttatt ttaattatta ttcccataat cgtttacagc
    10201 tatttggcag taaagaaatc agttttgcgg aacggatgat cccagaagag cgtttgatca
    10261 tcatgagaag attatgtagt gaagatatgc ccgcatttat tatttcaaga ggattaccgg
    10321 ctccagaaga aatgatccag gcagcaaatg aaaatgggat agctgtactg cgttctccca
    10381 tctcaacttc tcgtttatta ggagaattat ccagttattt agatggtcgc cttgcccctc
    10441 gaacaagtgt ccacggtgtt ttagtggatg tttacggatt aggtgtactg attcaaggtg
    10501 acagtgggat aggaaaaagt gaaacagcgt tggagttgat caaacgcggt catcgattga
    10561 tcgcagacga tcgagtagat gtttatcagc aagatgaatt aacggtgatc ggagaaccgc
    10621 ctaaaatcct ggaacatcta attgaaatcc gaggaatcgg gatcattgat gtaatgaatc
    10681 tttttggtgc gagtgcggta cgtggctcta tgcaagtcca gttggctgtt tatctggaag
    10741 catgggcaaa agataagaaa tacgaccgtc tgggctctga agacacgacc gttgaaatcg
    10801 cggaagtggg cattccacaa ataaaaatcc ctgtcaaaac aggacgaaac gttgcaatca
    10861 tcattgaagt agccgcgatg aatttccgtg cacgtacaat gggctttgac gcaacgaaaa
    10921 catttgaaga aagattaagt cgcttgattg aagaaaactc aggcaacgac tagcaaggag
    10981 tgacaatatg ttagcacaaa tcaatcgagt tgcttttgag cttgtaggga ttcctatcta
    11041 ctggtatgca ttgatcatcg tatcaggtat cattatcgcc atgtggctta gcagcagaga
    11101 ggctgttcgg gtaggattaa aagcagatga tgtgacagat tttatgttgt ggggattgcc
    11161 tatctccatt attggtgctc gcttatatta tgttttattt gatcttcccc agtatatagc
    11221 tgatccaatc caaatattca atatccgttc aggaggctta gctatttatg gcggactgat
    11281 tgcaggcgcg atcacgctgt atttttttac taaatatcat tttatttctt tgtggacttt
    11341 tttagatatc gctgcaccaa gtgtattatt agcacaggca atcggtcgtt ggggaaattt
    11401 catgaaccac gaagcatatg gaccagacac gacgcgaagc ttcttagaaa gtctgcattt
    11461 accgcaattc atcattgata atatgtatat cgaagggatc tatcgtcaac caacatttct
    11521 ttatgaatca ctttggagtt tgattggatt tattttgctt ttgtttttac gaaagaaacc
    11581 acaccttttg aaaaaaggcg aagtcctttt atgttatcta atgtggtata gtttcgggcg
    11641 tttctttatt gaaggattac gtacagacag tctttacttt ttaggtgtga tccgtatttc
    11701 tcaattatta tctgctgtgt tatttgtcgg tacattgatt ctatttattt ggcgcagaaa
    11761 aaaaggaaat ttaccggatt atgaccgctc attaggaaaa aatcaacaaa ttatctgatt
    11821 tttagagcgt taaaaatgaa aaaaatttca ggagtggtaa aatgaattat agagtagcgg
    11881 ttttaggacc aggctcttgg ggtactgctt tggcacaagt cctcgccgaa aacggacatg
    11941 acgttcggat ttggggacat cgtgcttcac aagtagaaga aatcaacacc caacacacga
    12001 atcaacgtta tttaccagat cattatctac ccgattccat ccaagcattc accaatatgg
    12061 aagatgcagt aaaagacgca gatgcggtgc tattcgtcat tccaacgaaa gcaatacgtt
    12121 ctgttgcaaa agaactagtg cctaaattga atacaaagcc agtgatcatc catgcaagta
    12181 aaggattaga acagggaaca cataaaagga tctctgacat cttgttagag gaaatcccag
    12241 cagaaaaaag aaaagctgtt gttgttcttt ctggaccaag ccatgcagaa gaagtagcga
    12301 aacatgacat cactacgatc acagctgcaa gtacagatgc aaaagcagca aaatatgtac
    12361 aagagctgtt catgaataat tattttcgga tctataccaa tcctgatgtg atcggtgtag
    12421 agatgggggc agctttgaaa aatattattg ctattggtgc tggcgctatt cacggcttag
    12481 ggtttggcga taatgcaaag gcagcaatca tgacgcgcgg attagctgag atcagccgtt
    12541 taggtgtagc aatgggtgcc aacccgctga cctttatcgg attaagcgga gtaggcgatc
    12601 tagtcgttac ttgcacaagt gttcattcta ggaactggcg cgcaggcaac ttgttaggac
    12661 aagggcagcc cctagaagag gtgctagcca atatgggaat ggtcgttgaa ggtgtgaata
    12721 ctactcaagc agcgatggaa ctagcccaaa taatggaaat cgaaatgccc atcactcaaa
    12781 caatctatga agtgctgtat gaacaaaaag aaatcaaaac agccgcaaaa gaaatcatgt
    12841 tacgtgatgg gaaaaaagaa aatgaattct cattaacaat tttttgaagg agcgaatgta
    12901 tatgaaagtc aaaaaagcag ttattccagc ggcaggatta ggaacaagat ttttaccagc
    12961 aacaaaagct atggcaaagg aaatgttgcc aattgttgat aaaccaacaa tccagttcat
    13021 cgttgaagaa gcgttgaaat caggaatcga agacatcttg atcgttacag gaaaagctaa
    13081 acgaccaatc gaagatcact ttgattcaaa tattgaatta gaaacaaacc taagtgaaaa
    13141 aggaaagacc gaattattga aattagtaga agaaacgaca gatgtcaact tgcatttcat
    13201 ccgtcaatct catccaaagg gtttaggaca tgccgttctt caagcaagag cctttattgg
    13261 aaatgaaccg tttgtcgtta tgctaggcga tgatatcatg gaagatgaag taccattgac
    13321 acagcaatta atcgatgatt acgaacgtac tcatgcttct acgatcgccg ttatgcaagt
    13381 tcctcatgat gaaacttcaa aatacggaat tatcaatcca ggagaagtat tggaagatgg
    13441 gttatacaat gtcaaaaact ttgttgaaaa accagatcca agcaaagcac caagtgattt
    13501 agctattatt ggacgttact tattgactcc agaaattttt gatgtattgt ccgagcaaca
    13561 accaggagcc ggaaatgaaa tccaactaac tgacgcaatc gatacattga ataaaacaca
    13621 acgcgtattt gcccgtaaat tcacaggtaa acgttacgat gtcggtgaca aatttggttt
    13681 tatgaaaaca agtattgaat atggtctaac acatccagaa gtaggtgcac ctttacgtga
    13741 gtatatcctg tctttaggta aaaaattaga agcagaagga agcaagatcg atcataatcc
    13801 aaaaggaata acagaaatca aagaagaaaa gaaaaaataa cccttttttc taacgagctt
    13861 cagctgctaa ttgaataaaa agtagttgaa gctcgttttt atttgtttaa aaaacacgaa
    13921 aatgctatcc ttatagaaaa gagagacaag aagggagttt gatcatgtca ggaggagaaa
    13981 ttgcaggatt gatcgcagca atcgcctttg cgatacttgt cgtttttatc gttcgtgtgt
    14041 tgttgcaagt ttctaaaact ttagaaaaag tagatcagac tgtagcagaa gcaaatacga
    14101 cgatcgaaat cgtcacaaaa gacgtagatc ttttgtctag acaagtagaa ggcttgctgg
    14161 tcaaaagtaa tgaactgctc ttggatatca atggaaaagt cgcaacgatc gatccattgt
    14221 tcacagcagt tgctgattta agtgaaagtg tatcagaact taatcattct agtaaaaaca
    14281 tcgcgacgaa agtcggcgga atcggtaaaa cgacagctaa agcgacggtt gccggaaaag
    14341 tcggtgggac agcgatgaaa ttttttaaaa acaaaaaaca tactgaaacg acaggaggaa
    14401 aataaaaatg gctaaaaaag gtggattttt attaggtgca gtagtcggag gaacagccgc
    14461 agcaatcgcc gcgttattgt tagcaccaaa atctggtaaa gaacttcggg atgaattagc
    14521 tgcccaagcg gatgatttga tggatatggc ttcagattac acagatatgg cgaaagaaaa
    14581 atcgactgag ttaacaggta ttgcaaaaga aaaagcgcaa gatctttctc aacaagcagg
    14641 tgatctagca ggtagtgtca aacaaaaagt aagtgaatca gcagatgaag caggaagtga
    14701 atctgacgat atcttgttaa atcttaaaga acaatcagct gacttatcta atcgtttcaa
    14761 aaaaacggca gaagatatga aaaaacctgc agatgaatta ggaagtattg ctaaagatac
    14821 ttcagaagat atcatgattg atgtaaaaga cgctgctggt aaagcaggag atactgtcaa
    14881 tgaaggaatg tcagaagcaa aaccagttgc agatgacaca aaagaaatga tgaaaatggc
    14941 aaaagaagat gcgaaagaag ctaaaaaaga aataaaagat acaatgacag attcatctac
    15001 aaatcactaa aatcactaaa atcacaaatt tatagaataa aaaggtggga gcggactagc
    15061 tctcaccttt tttactctta tttttctaaa actagtaatt cttttggtgt agtcgtgaat
    15121 ggcacacagc catcgcttgt cacatataca cagtcttcga tacgtacccc tactttttca
    15181 ggaatataga ttcctggttc aagagagaag cacatccctt cttcgattac taagtcattt
    15241 ccttctacaa gggaagggaa ttcgtggacg gttgttccga tcccgtgacc taaacggtga
    15301 ttgaaatatt cgccgtagcc atagctgttg atcacgtttc gtgcgatttg atcaagttca
    15361 cctgctgtca cacctggacg gacggcttct tgtgcggcaa gctgtgcttc aagagtgatg
    15421 ttgtatattt tttcttggaa gtcggttggt ttttgataag caattgtacg agtagcatca
    15481 ctgcaatagc cattccaaac aacgccaaga tcgaataaca caagttcatt cggtgaaatc
    15541 ttcgtgtttc ctggtgtacc atgagggctt gcagcatttg ctcctgcaag gactaatgtg
    15601 tcgaaagaca tttgtgaaac accttgtttt ttcaattggt attcgatttc tgcaatgatc
    15661 gcttgttcag tcacgccttc tttcactgct ttaaagccaa tctcaaatgc aacatcggcc
    15721 catttaccag cttcgatcag tttgtctttt tcctctagag ttttgatcag ttgtagacgt
    15781 tggatgatgg aagctagatc agtgtaagaa tccgttcccg tcaagatatc agagatagca
    15841 tcgaagcgct cgacagtcaa ggcgttcttt tcaatcccta cattgccagg ctgaccatag
    15901 cgagcacgaa gttcttttcc gatgatctcc caagggtttt cgctgtctaa atagccacgg
    15961 acatcatacg cccaactact gttttgagca tcttcaactt ccaaagcagg agtgaaaagg
    16021 aaaggatctt gttcaagagg gataaaaaga gctagtacac gctcatgagg atcactttcg
    16081 tatccggaaa agtaagcgat gtggccaggg tcgctgatat aagccaattc gacttggtgt
    16141 tgtgccatcc attgacgtag ttcattgatt tttacgttat tcatttggca acctactttc
    16201 taaattaatt ttgtattcaa taattgtacc actgatttat taaaagacca acgttctaaa
    16261 aactgaaaaa agtaaaaatt ttcatgaaaa cagagataaa acggttgcaa ttcttgagat
    16321 tatttgatat tctattttag aaatgtaaga cgtattttca gaaaacatat aaaatatgaa
    16381 taggagaaca caaatggaaa agcaaacaat cactatctat gatgtagcga gagaggcaaa
    16441 tgtttcgatg gctactgttt cacgtgtcgt aaatggcaat ccaaacgtca aaccagcaac
    16501 aagaaaaaaa gtcttggaag ttatcgatcg cttggattat cgtccaaacg cagttgcgcg
    16561 tggcttggca agtaagaaaa caacaacagt tggggtaatc atccctgatg tcagcaatat
    16621 gttctttgct tctttagcac gtggtatcga tgatgtggca acaatgtaca aatacaatat
    16681 tatcttagca aattcagatg gtaacgacca aaaagaagtc aatgtattga ataacttact
    16741 ggctaagcaa gtggacggcg tgatcttcat gggtcaccat atcacagacg aaatccgtgg
    16801 agaattttca cgttcaaaaa ctcctgttgt attagctggc tctattgatc cagatgaaca
    16861 agtaggtagc gtaaacattg attatgtatc agcaacaaaa gatgcagtaa acaaattggc
    16921 aaaaagcggc aataaaaaaa tcgcttttgt cagtggtgcg ttgatcgatc ctatcaatgg
    16981 acaaaatcgt ctgaaaggct ataaagaagc attaagcgaa aataacctac catatagcga
    17041 aggattgatc tttgaagcac aatacaactt caaagatggt ctatctctag tcgatcggat
    17101 ccataatagc ggtgcaacag ctgtctatgt ttcagatgat gaattagcca tcggtatttt
    17161 ggatggttta ttagaccgtg gcgtgaaagt accggaagaa ttcgaaatca tcacaagtaa
    17221 caattcacta ctgacagaag tagctcgtcc tcgtttaaca agtatcacac aaccattata
    17281 cgatttaggg gcggtatcta tgcgcctatt gacgaaaatg atgaataaag aagaagtcga
    17341 agaaaaaacg attatcttgc cttatggaat cgaagaaaaa ggatctacaa aataataaaa
    17401 ggacaaccat tcagaggttg tgagcctgcc gtttaactct gcgttacaag gagcaatttc
    17461 aaaaaacagc atttcatgtt tgatgaatat tgtgactcgt gattcggagt tggcaggaga
    17521 acaccgttta ttcgggaaaa ggggttatga caaaattttg tttaatcctt tttttttgtc
    17581 ttaaaaaaga gagaaagtgg ttgaaattac atttatcgta tataaaacaa tccgtgtata
    17641 gatgctgcat tatgttcacc accatcaaaa aaataaggga ctgtgacaat actattgtca
    17701 cagtccctta ttactgtgta ttctattaaa tcaatcatct ttctcatctg attctttggt
    17761 tgcttgattc gctcttgcat aagctgaagc ggtgttccag taatctgtat agttttcatc
    17821 ggtaccgcca acgccaaatt taaaggcgct tttcttcggt ccatttttcg cccatagcga
    17881 ttcaactgtt tttcctggtg tttggatgga ttttttattg acagtaactt ttccaggtgt
    17941 ttgaccagta aatccagata cttttttctt catcacatca gatgataatt cgaatttctc
    18001 atcagtgcca aaaatgtcag gttttgcttg gtaagcttga ttgatcagat tggcaagata
    18061 attagccgaa cgtatccttg ctttgctgtc cattccagta ttgtcatcgt gccctgccca
    18121 gctactgatg gtaatagacg gagtagagac aattagccat gaatctcggt attcattggt
    18181 agaaccagtt tttccgaccc aatctgcttt tcctagattt ccgtttaagc ttgagatggc
    18241 atctttgaat ggtgtagtga tttttgcatt gatcacactg cgcatcatgt cattcatgat
    18301 cgatgccgtt gcttccgaat agatccggac agagttgctt tcgtgtttat aaattacatt
    18361 tcctgcgtta tctgtgatgg aatcgatgat atagccttct tcatagacgc cgccgtttgc
    18421 taaagcctga aatccattgg tctgttgaag cgtcgtgaca tctactgtac ctaaaggagc
    18481 agattcaacg ccccaattgt catttgccgg gtagttcatc tttgccaagt agtgctcgta
    18541 agcatattgt ttcgatccac cggaattcaa cacatcttga tataagtgat aagccgggat
    18601 attgttggac cattctagtg actcacggac ggtttggaag gtgttcgatc cttcgttagt
    18661 agcattgacg attttctcgc cagcattttc tccttcttgc caagttgttg cataatctga
    18721 tacacgggat tctgatccga taagccccat gtcgattgca ggtccataaa caagaactgg
    18781 tttgattgat gagccagctt gacgttctgt atcgaaggca tggttatttt gattctgact
    18841 gtaattccgt ccgccaacga atccgtagat gcggccagtt ctgttatcca tcaatacatt
    18901 tccggtttct acttgactgc cagcaccatc atctaacatg tatccataat tttctacgcc
    18961 attttgcaat gcagcataga catctttatc gattgtcgaa tggattgtat atcctttatt
    19021 ttggatcgtt tgctgtgcct tttgataata agcgtcactg accgatgaat cagacatatc
    19081 agcgttgtct ttttcagcca attgttgtgc aatgattctt gttgcttcat tcatcacagt
    19141 ataatacaag aattctctgt cagtctgttc tgcgatttgt tgtggtagaa agtcttttgt
    19201 aaggtcatag gcttttgctt cttcgtattg ttctttcgta atttggcctt cacgatacat
    19261 actgaataaa acaaaatctt ttctggcaag gccggcagaa agatcttctt ttagcgcacc
    19321 tgtgttcgtg tatggactat acgtgatcgg gctttggggt aatccagcga tataagcagc
    19381 ttgcggcagc gtcacatctt ttgcatctac accaaagatt cctcttgcag cttcctggac
    19441 tccagcaatg ttttgtccct tattattacg accaaatggt gagacattca aatacgtagc
    19501 aatgatctca tcttttgaaa agtatttttc tacttgtgca gaaagaatga tctcgtttgc
    19561 tttacgtttg aatgttgttt catctgtaag gatctgctgt ttgactaatt gctgtgtcaa
    19621 agttgatcca ccagaagagc caataccagt agcttcagat actaatgctc gtaaaacagc
    19681 tttaggaacg taaccttggt gtttatcgaa gtattcatcc tctgtgctga taattgcagt
    19741 tttcaataaa ggtgaaattt tatcagatga aatagtcgtg cgcatcagat ctgtctggat
    19801 ttttgatatc tctgtattat ctgcataaac aatctttgac gtttctgtaa tgtttcctag
    19861 ttctgtctgc agtgcttttt tagtcggcaa ttgtgtgtct tcgacgagat aggcaaaata
    19921 gccagcgcct attccaatac ctagagctgc gaacatcaaa agaagaacag taataaaaac
    19981 agtcaatgat tgaaaaactc taaaaataat cttaggaaca aaccattttt ctttttttct
    20041 tctattctgt ttttttcgag tatttttgcg tggcaaaagg gtcacctcaa ctaatggttt
    20101 tatttcgcta attatagcaa ataatagaac aaaaaaacag acaaggctgt ttttggcagg
    20161 aatttctttt ttaaaagagt taaaacgtga gaaaatgatc ttttttataa aagagttctt
    20221 aagcttttct ttagagaaaa tttcagttac tatggagaac agggcaaaga aaaatcaatc
    20281 attttctttg tatatcatct taccaatata taggaattgt tagtaacaat tgcctttcaa
    20341 ggaggaatcc atccatgtta ttaggctcac acgtcagcat gagcggaaag aaaatgctgt
    20401 taggagcagc agaagaagca gccagttatg gatcttcgac ttttatgatc tatacaggcg
    20461 cccctcaaaa cactagaaga aaagccatcg aagagatgaa tattgatgcc ggaaaagcgt
    20521 acatggcaga aaacggtcta acaaatatcg tcgttcatgc cccttatatc attaatttgg
    20581 ggaatacgat caaaccagaa atgtttcctt ttgccgtcca atttctgaga gaagagattg
    20641 ttcgtgcgga agctttaggc gctactcaaa ttacacttca cccaggtgct catgtagggg
    20701 caggaacaga agccggaatt gctagaatta ttgaaggctt gaatgaagtt ttgacaaaag
    20761 aacagacggc acaaatcgct ttggagacaa tggcaggtaa aggtacggaa atcggtcgaa
    20821 catttgagga attagcgcaa atcatcgatg gagtaaaatt gaatgaaaaa ttatccgtta
    20881 cttttgacac ctgtcatacg aatgatgccg gttataatat taaagaagac ttttcaggtg
    20941 taatggaaga gtttgataag atcatcgggt tagatcggct taaagtactc catatcaatg
    21001 attctaaaaa tccgcaaggt tcgcataaag accggcacgc caatattggt tttggaacaa
    21061 tcggattcga cacgctgaat aagatcgtcc atgatccaat gtttgacaat atttcgaaaa
    21121 tcttggaaac tccctatgtc ggcaaagata aaaagaaagc ttacgcacca tatggaaaag
    21181 aaatcgccat gttcaaagca caaatattcg atccagaagt gtttcctgag ttattagcag
    21241 aagaagtgat actctaagat tttctatctg acagcagcaa aaaaggacca ggcacattgc
    21301 cttgtccttt tttgtttaag aaacaaagga gtgctttttg cagtcttttt catcatgcat
    21361 cttctccccc ctctttttaa atttagacaa acagggtata ctggtagaaa agtaaaaaaa
    21421 cgaaaagttt cacaagcaag tggcaaaacg tgattggaag gacgaaaaga tgctgaacac
    21481 tttaaaaccc ttgatcaacc aactaaaaaa gaaacataca tactttattc ttggcatagc
    21541 cctattattt acaattattc gtttgtattt atatagtaaa gcaatctatg gaacagacat
    21601 gtcggcaacc tatgatgacc agctgctgat tcgctatgct caaaatattt tggacggtaa
    21661 atggctaggg gagtatacga ctacaacact ttccaaagga atctcctaca gcttattttt
    21721 agtacttgca cataaactgc atctttctta tgcagttttg ttcggcatgt tcagtatttt
    21781 tgccagtata ttggttgcac tcgcgtttaa accgatcgtg aagaacaagt atcttctttt
    21841 aagtttctat ttttattttt tgttttctcc gattagtttt acacatgaat attccactcg
    21901 aacgtatcgt aatgccctcg tgattccggc tgttgagatc attatcgctt gtttactagc
    21961 tatttattac cgtaaatata gttccagcaa aaaaatgctg ccgtggtttt tagggctagc
    22021 tgtttctttt cctttctttt ggttcattcg cgaagattcc atctggcttc ttccttttac
    22081 tgtagtcgcg ttaggcatca gtttcgtcca gatcttgcta ggacaagact tttctttcaa
    22141 agaagcaaag aagttaaaag aacgaccatt tctcctttcg aaacaagaat ggctgaaact
    22201 ttcattgttt ttactccctc tagtcggttt ctccatcgtc tatcagtgga tcgaatataa
    22261 aaacgagaca acatatagta ttgccgccat caatgaccgt tcgagtggcg aatttggacg
    22321 tttgatgaaa cagctgatcc gaatagatga cgaaacgaac ttaaataaag aaaacagtga
    22381 gatatgggtc tcgcatgctg cattaaataa agcattagac gcatctccta catttcatgc
    22441 tgtttctact cgtattgacg aattgtatac gactcatgcg tggacccaag gtggaaaagt
    22501 aaaagaatta ccaggagata tcattttttg ggcattgcga gatgtggtaa gcgaatctgg
    22561 ttattaccaa aacaatgcaa aagaaaccaa tgatttttgg aaaaaagtca atcaagaatt
    22621 agaagaagcc tatcaaaagg gaactatcaa aaagaaaaaa gaattctatc tgatgggatc
    22681 aggggatgga aagacgatga atgatctgcc aatcgtattt gcttttctga aatcaggata
    22741 tgcctatgca tggcgataca aagatttcca tcaagggggg aattatagtt tcggtacgca
    22801 agaacaagtc gaacaggccc aagaattatt gaatcttcca ctaatggata attggatcga
    22861 tagcagtgat ccgagaacac ctgatttcca gttgacaaaa acagcaaaag tcgcgaatgt
    22921 catgataaaa atttaccaag ttctggccat tcccgtgctg attgcttcaa tagcagggat
    22981 attacttatg atactaggaa ccgcatttgc aaaagctgat cgtgcctatt atagttcctc
    23041 tttgattgta gtcaccggat taatactgac acaattggtt tttcttttcg gcgtctcgtg
    23101 gttttgttct tatgcgccag aaaaaaagga ttatttttta agtgtctaca ctggcgcagg
    23161 cgtgccatta acgcaattca tcgtagtaac aagcatgcta gttttcagta aattgaatct
    23221 gaaaaaagct ttatcttcca aataaaaaca tactaagatt agaggagaac atcattgacg
    23281 aatgatgttc tcctctattt tctattttta gattatagtg aagagtgaaa gaaagttcga
    23341 acaaagcctt gaggacta
//
LOCUS       DADGHT010000041        22901 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.041, whole genome shotgun sequence.
ACCESSION   DADGHT010000041 DADGHT010000000
VERSION     DADGHT010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.041"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(160..444)
                     /locus_tag="JX887_001447"
     CDS             complement(160..444)
                     /locus_tag="JX887_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257443.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(462..1352)
                     /locus_tag="JX887_001448"
     CDS             complement(462..1352)
                     /locus_tag="JX887_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAX1257444.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1372..1590)
                     /locus_tag="JX887_001449"
     CDS             complement(1372..1590)
                     /locus_tag="JX887_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257445.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1560..3240)
                     /locus_tag="JX887_001450"
                     /pseudo
     CDS             complement(1560..3240)
                     /locus_tag="JX887_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
     gene            3507..4280
                     /locus_tag="JX887_001451"
     CDS             3507..4280
                     /locus_tag="JX887_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257446.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4361..4930)
                     /gene="thiT"
                     /locus_tag="JX887_001452"
     CDS             complement(4361..4930)
                     /gene="thiT"
                     /locus_tag="JX887_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAX1257447.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(4996..5098)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5104..6075)
                     /locus_tag="JX887_001453"
     CDS             complement(5104..6075)
                     /locus_tag="JX887_001453"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAX1257448.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6169..7542)
                     /gene="glmU"
                     /locus_tag="JX887_001454"
     CDS             complement(6169..7542)
                     /gene="glmU"
                     /locus_tag="JX887_001454"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAX1257449.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8045..8863)
                     /gene="purR"
                     /locus_tag="JX887_001455"
     CDS             complement(8045..8863)
                     /gene="purR"
                     /locus_tag="JX887_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAX1257450.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9030..9854)
                     /locus_tag="JX887_001456"
     CDS             complement(9030..9854)
                     /locus_tag="JX887_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAX1257451.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9827..10507)
                     /locus_tag="JX887_001457"
     CDS             complement(9827..10507)
                     /locus_tag="JX887_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAX1257452.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10530..11468)
                     /locus_tag="JX887_001458"
     CDS             complement(10530..11468)
                     /locus_tag="JX887_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAX1257453.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11713..12564)
                     /locus_tag="JX887_001459"
     CDS             complement(11713..12564)
                     /locus_tag="JX887_001459"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAX1257454.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(12718..15291)
                     /gene="mprF"
                     /locus_tag="JX887_001460"
     CDS             complement(12718..15291)
                     /gene="mprF"
                     /locus_tag="JX887_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAX1257455.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15432..16238
                     /gene="proC"
                     /locus_tag="JX887_001461"
     CDS             15432..16238
                     /gene="proC"
                     /locus_tag="JX887_001461"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAX1257456.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16317..17873)
                     /gene="rny"
                     /locus_tag="JX887_001462"
     CDS             complement(16317..17873)
                     /gene="rny"
                     /locus_tag="JX887_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAX1257457.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18284..19333)
                     /gene="recA"
                     /locus_tag="JX887_001463"
     CDS             complement(18284..19333)
                     /gene="recA"
                     /locus_tag="JX887_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAX1257458.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19442..20683)
                     /locus_tag="JX887_001464"
     CDS             complement(19442..20683)
                     /locus_tag="JX887_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAX1257459.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20923..21501)
                     /gene="pgsA"
                     /locus_tag="JX887_001465"
     CDS             complement(20923..21501)
                     /gene="pgsA"
                     /locus_tag="JX887_001465"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAX1257460.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21710..22594)
                     /locus_tag="JX887_001466"
     CDS             complement(21710..22594)
                     /locus_tag="JX887_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1257461.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
BASE COUNT         6515 a         4985 c         3968 g         7433 t
ORIGIN      
        1 aataccgaga aaatggtttt tgaacatcac ttattcaaaa taaaaaaaga ttgtgacacg
       61 aattttgtca caacctttaa atgtattcct agagcaaaga agctaagcga agaaatccaa
      121 ttctgattat ttattgtatt tctttgttca gcatccttgc taaaagccca tattggacaa
      181 agtattcact acacccatga tctcatcttt tcgagaacgt gctttttctg tcggatcttc
      241 tacctcttct gtgtcaattc gaacaataaa tttccgattc atcgtcacgt aagcaccgtc
      301 gttgatcaaa ataaacagtt cgttctcatt atagtctgca caggcatctt tccatacgtc
      361 aaagccgttt ttttcagaag ggatatcccg tttaaccaca gtttttccac ttaattcgtg
      421 gaacgttacg tcataatatt tcattatctc tacctctttc gtcattcaat attttgtact
      481 tgttctctga ttttttctaa gatcgtctta gactggacga cttgattttt aatttcgatt
      541 gcatttgatt tggaaccgat cgtgttgatt tcccgattca tttcttggat caggaaatct
      601 aattcccgac ctacaggaca ttgtgcttcg ataagttcat ctagtttttg tacatggatc
      661 gccagacgat ccagttcctc gtgaatatct ccgcgttcca acaagatggc tagctccgtc
      721 aacaaccgtt gctcatcgac tttcgctcca agaaattcct ccagcttttt ttgatacctt
      781 atttgaaatt ccttttcata gatttctaca aaactatcga gtttttttag tacttctttg
      841 aattcttcag tattcttttt caacactaaa gctaaagctt gaccttcttt ttctcgactc
      901 gcctcaatag aatcaagtgc gcttttcaat gtatctagag ctaactgtgc caattcttcc
      961 atgctctctt ccggtttttc ttctaccgtt acgaagtttt cgtccagcgc gaagcgttcc
     1021 gccatccgac taattgacac ttgattttga ctaccgtatc gttgttgaat tccgtctgtc
     1081 aattgagtga taagtgaatc aatcaattcc cagttgatga cgatctgttt ttcgtttttg
     1141 ccaatataag ctagattcac aaatacttcg attcgaccgc ggcttaactg ctgtttaata
     1201 agctgacgaa aatcgttttc aacaaagttc aggattttag gacttcgtat ttgaacatct
     1261 agaaaacgct ggttgacact ttttatttca atatctaact gatacgcttt tgtttcgcgg
     1321 atggctttgc caaaaccagt catacttttc attcgacagg gtccttcctc attacatatt
     1381 ttctattgct ttttgcagtt gttcaaactc ttcgttcgtc aatgtcaggc ctttccccat
     1441 tttttcatgg tctggcgccc aatctcgaag atcgaatttt ggcgggcgac cattccagct
     1501 gactaggttc agttctttac gccacccctt gttgttttct gacaatatag cgatttcttc
     1561 tacgatttca tatgaaaatt cttgtgccat ggttgttcct ccttgagata atataaatat
     1621 aggatcagta atgtgtcaac tggttgctta agcaattcat gctgcaaacg atccttgcgt
     1681 tttccttgta gcagataatc aaaataaaca gttttcgtgc gctcattttg tattttttgc
     1741 tggtattttc gataccttcg ccattcttca gtacttaatt gaccaatttg tgccaataaa
     1801 tcatccggca tactttttat atcttgttgg cagatcattt gaatcatcat gtctacttga
     1861 tagatttcat tgggcagtaa aaaatgtttt tttgctaaaa gttctagcat cgccaatccg
     1921 catgtctctg gtacgaccct gttcttatat aaattacgca gtttttgcca aaattttatg
     1981 cttttgaaaa aagataattc taactgaatt tcttttgtta agtaagacaa aaatcctcgc
     2041 cagtatgttc ttgcaggttt aacagaatga aatgtatacc agttcccata gtaatagcct
     2101 aatcgttttt tcatttccag atagcctaat tgtaaattta attggttcct ttggctatca
     2161 aaaagcagaa agctgcctag tgtccacaat gtttgacatt tccaatggat aaaaatgtct
     2221 ggcatacgaa tttttttcgc tgggcctggc ccttgcacat ctacgacaaa tgcctctgtt
     2281 gctcctttgt taatcgcaat atcaataggt attttgttgc gatacccacc gtctgcatat
     2341 ttattttttc cgatctttcg ataagccata gcgggataaa atgaagcaga ggcgagtatc
     2401 caatctggta tttcttctgt ttttgtctgt tggatatcag tcactacttc cgctagttct
     2461 ggcagtttag tagacaccgt atataaacgt attttgggat tatgtttgag taaggacaaa
     2521 tccaaattgt ctttgaccat cttttccaat ggagcagaag aaaccccgcc ttcaattagt
     2581 gctgttttcg tcatttggcg tctttctcga tagaagcgtt cacgaaggtc ttcaactgca
     2641 gccatttctg gtaacgcaag cacttgtctt gtcgacagct tttttcatat ctccttgtaa
     2701 aatcaatgcg ccgttcaacg cacctaccga ggtacctgtg ataatctcaa agttgatatc
     2761 atgttccttc agcgcctgcc acacaccaat ctgataagca ccgtgcgctc ctcctccacc
     2821 taaaacaagt gctgtatgat agaccagctt tttatttaat tgtgtggttc cttgatagcc
     2881 gtttttatga aaaatacgca accattcttc tgatagagga gattgaaata aaaaacaaca
     2941 gttttcttta ataaaaaaac gagcgcaagc ttccatatac cgaaaaaatt ttttccattc
     3001 aaaagtttca ccttcaatca acagattatt aaaaataaca tctcctctac ttttagcaat
     3061 agtaaaatag acggtatatt ttttcgatac tgctttaaaa gcacattgct tttttgcaga
     3121 acgccaaaaa gcgtctctac tttcttgatg actttgaaaa aatggaaggg gttgttttgc
     3181 ttgctggata ggcgaataca gcgacatttt ctgtgaaaag taaacttttt ttatctccat
     3241 cgcgctctcc tttttcttca agtataccag tacgtcataa aaaggtcatg agtctcgtat
     3301 tcgactttgt agattccata agaaaacaat tcataaaacc tcctttaaat aaaaaaatac
     3361 aaaaatcaca aaaattaatt gaaaatgaga gtgttttcaa tgaaaacgtg attttgtaat
     3421 ggaattttaa aataaaagaa acaagctttt ttaatgcaaa tgttgtaaaa taaaagagat
     3481 taagaggaaa taagaggagg aacatgatga ctgagtcagt ttatgtacat attgatacca
     3541 caagtaatgc tgttttaaca aaagggctga ctgctactga ctttgcaaac agtatcgtgc
     3601 attttcctca aaacttgctc ttgcttgatc catctgcttc tgctggagaa tatgaatccc
     3661 atacagggct gaaagtaatc cgtggtacag aaaatattca gcgtttcttt tcctcttctc
     3721 gtaacaggcg tggattcgat gaattgaagt ggatcgactt tactgattta acgatgctga
     3781 aagaattgac acctttagaa atttcagaat tattatattt tggtcatatg aaaacacatc
     3841 ttcattcgcc gtttttttat aaactacaga ataattttgt atacttcgat cttaatgatc
     3901 agctgaatcg gatttattat cgctatttag atgaatttta taggattttt gctagtaaat
     3961 taagttcgat cttgtcagat aagatcaatg taaaaaaatc ttttttcaaa aaagaaacac
     4021 ctgttgaaaa aatcagtgtg gaattattga aagaaatgcg taatttgatg caggaaggga
     4081 tcattttttc ttttgatcaa gttggtttga tcgatggtaa atatcgtatc ccaatctatg
     4141 tgattgaaga ttatatttgg aaattaaaag gcacccggta tcgagaagag gaaatcatcg
     4201 ctactttaat ctactctgtc accgatcgac actggcaatt ggtagaagat gccgatcttt
     4261 cttatctgcc attgaagtag atctatttct tatcaaaaaa taaaaaggaa acaagaaact
     4321 aggacatgat tctgtctcaa gtttcttgct tcttttttat ttacagctcc tgtcgtttat
     4381 ctggcacaaa aatcgaagga gtcgtttgtt ggatccctaa taaaacgatg atcgttacaa
     4441 tagctgtact caacccgctg gcaccattca ttacgaaaga aaagagccaa ggattcatcc
     4501 cccatagtgc atacgctccc cagaaaacca ctcctgcaat aaaatgccaa aaatatctgg
     4561 aaagtgcgcc aatcaatgca ccaaacacga tgctttttct aatttgtttc gtattatcgt
     4621 ctacatagcc tttttggaca tttgaagcca tgagccctgc tgcgcctgca aaagtatagg
     4681 caatcgggta ctcaatcaac acttgaacga cacttaaata ataaacttgt cccaacggaa
     4741 aatgtaggat gccccaaatg aaacctgcca gcatccctgc ctttgtccct cttcttaacg
     4801 caaaaagagt caatggaatc tgccctaatg aaatagaaaa actgctgccg atctggatcg
     4861 gaatcaacga caacaccatc gctaacgctg caacaatcgt tccttctacc caaactctat
     4921 tttttcccat aaaaaaactt cctcctttga ataaaaaagt cacaaaggag gaagcagctt
     4981 tcgaaaatag tcaaacagct gtttattcac aattcctacg ctcgcataac cgatacaggt
     5041 acgaagggtt tagaaataga ttcaatctca gcccaattgg actccccttt gtgagtttat
     5101 ttattattta ttttttgttt caaacaatgg actaactggt ttgttttcat ggatacgttt
     5161 gattgcatct cccattagtc cgccaacact tacttcatcg attttgtcga ttttacgatc
     5221 ttctggaaga tagatcgagt ctgtaacaac tagacgctcg atagctgaat cttctattct
     5281 ttgtaaagca gggccggata atactggatg tgtacatgaa gcatacacac tagttgcacc
     5341 agcttctttc aaagcattgg cagccaatgt gatcgtacct gctgtatcga tcatatcatc
     5401 gatcagtaca caagttttgc ctttgacttg tccaatgata ttcattactt ctgcaacatt
     5461 tgcttttgga cggcgtttgt ctatgatcgc aatcggagat ttcaaaaatt ccgctaattt
     5521 acgtgcccgt gtgacaccac catggtctgg tgaaacaacg acaacatcat cgcctttgat
     5581 tcctttttct aagaaataat tggcaataag tggcgcaccc atcaaatgat cgactggaat
     5641 atcaaagaaa ccttggattt gaactgcatg aaggtccaaa gtcagcattc ttgttgcacc
     5701 agctttttga atcatgtttg ctactaattt cgctgtgatt ggttcccgtg cacgtgcttt
     5761 acggtcttga cgcgcatagc cataataagg catgactacg ttgattgttt ttgcacttgc
     5821 tcgtttcagt gcgtcaatca tgatcagcaa ctccatcaag ttatcattga ctgggctgct
     5881 cgttgattga ataacataga catgcgatcc acgaatactt tcttcaatgt ttacttgaat
     5941 ttctccatca ctaaattgag taacagatga ttttcctaac tcgacgccga ctgctgctgc
     6001 aattttctct gctaatgggc gattggaatt taacgcaaaa atttttaatc ttgggtcaaa
     6061 gtaatgtttt gacatgggga cctccacttt ctttttcaca actctagaat tctacctaat
     6121 aaatagtagt catatttttt aaataaatca agtgattttg caaaagtctt agtttagata
     6181 agggagtttt tttgcatatc cttctttatt gacttgtctt gctctcgcaa ttgccagcgc
     6241 atattctgga atattgtctg taattgttga cccggcagca atcgaactgt ttttagctac
     6301 ctcgacaggt ccgatgatat tcgtgctaga accaataaag ctgtggtcgc cgacagtcgt
     6361 atgatgtttg ttctttccat catagttgac gaagacaaca ccacatccga cattgatttc
     6421 ttctcccagc gtagcatcac caacataagt caagtgaccg actttagttc ctttgccgat
     6481 ttgagcattt ttcacttcca caaagtttcc gatatggacg ttttcgccaa tttcagcttt
     6541 tggtcgtaaa tgtgcataag gtcccacatc tgcatgtttc ttgacatggc tgctttcaat
     6601 gactgagttt tcaatgacga cgtgatcctc aatcctactg tctacgattt ttgaatgtga
     6661 cccgatgaca caatcagaac caatgactgt atttccttgg atttgtacac ctgcttcgat
     6721 caatgtgtct ggaccgattt ctacgcctgc atcgatgtat gtcgttgctg aatcgacaaa
     6781 gcttacgcca ttgaccatat gcatctggtt aattcgcttt ctcatgatct catttgcttt
     6841 agctaacgcg atccgatcat tgactcccat tgattcttca aaatcatccg tttgataagc
     6901 agcaactgta tggccttctt cttttaagat ttcgatgata tctgttagat agtattcacc
     6961 ttgagcattg tttgttccaa ctttgcttaa cgcatcgaac aaagcttcgt tgtcaaaaca
     7021 gtaagttcct gtattgattt cttgtacaag agcttcttct ggtgttgcat ctttttgttc
     7081 cacgattttt tctacgatcc caatatggtc acggatgatt cgtccatatc ctgttgggtt
     7141 ttctgcttgt gccgtcaaga tcgttgcact tgcatttttt ccttggtgat attcaaaaag
     7201 attgttcagc gtttcagtag tcaataatgg tgtatcgcca ctgataacta acgttgttcc
     7261 tttttttcct tccaagaaag aagcagcttg caaaacagca tgtcctgttc ccaattgttc
     7321 tgcttgtaac gcatatttac tgcgttctcc tagttgtgct ttaacttgtt ctgctccgtg
     7381 tccaacgatc gtaatcactt catctggttt cgtttcactg acccgattaa tgatatgttc
     7441 taccataggt ttaccagaaa cgggatgtaa aactttatat aattttgact tcatgcgggt
     7501 acctttccct gccgccaaaa taattgcata acgtgcgtcc aactgcgtca ctcctaaata
     7561 tagtttgctg atttcagttt atcccagtat acccattttt tcaacaaaac aagtgatttt
     7621 cttttatccc agcgttttct ggataaaaaa atagatagac cataacgggc ctatctattt
     7681 ggtaaccggt gctctcctgc caactcctcg gtcacaagtc acactactca taaaacatga
     7741 aaagctgttt tttgaaatcg tttcttgtga cttagagtta aacggtaggc ttacaacctc
     7801 ttcattaaac gtttttcaat cagctgacct tcggtattag ctcaataaac ggcaaaatat
     7861 gaggagcaat ttttccgttt attgagctaa tactcaggac aggacgctga tttcacaacc
     7921 tctagataaa cggtgttcaa aagccagttt ctcggtatta agccaaattt atgaaaaaat
     7981 gtggaaagcc attttcacaa aatttttctt actactcgaa actaagcagc tttttcacaa
     8041 cctcttattc tgaaaaataa tttcctggca caaccgtaat atttttcgtt tgagtatcta
     8101 catctttgac ataaagcagt gacgtataat catcgatggc gcgatgaccg ttgaattttg
     8161 attcggcaaa tacagtgatg ccaacaagtt ctgattcgaa ttcttcaatc aagctcttca
     8221 ttccgttgac tgttccgccg cctttcatga aatcatccac tacaaggaca cgtgaaccac
     8281 gtttcaaact tctcttagac agttccatct tttcaattct ttcagaagat ccagacacat
     8341 agttgacact tactgttgat ccttctgtta tttttgagtc ccggcgtaca ataacgaatg
     8401 gcgcattcag ataataggac acagcttggg caataggtac gccttttgtg gctacagtca
     8461 ttacagcatc gattttttca ccaaggtatt tagaagcaat gattcttcca acttgacgca
     8521 gcagttcagg ttctcctaac aaatcagaga gataaacata tcctcctgga agcagacggt
     8581 cttgttctga tagacgttct gctagagatt caatatattt tttcgcctct tcatatgaaa
     8641 tttcagggat gaacaataca ccacctgcag cacccgggat tgtttccaag gttccatacc
     8701 ctcgttcttt aaatgttttc ttgatgattc ccaaatcttc actgatagaa gatttagcag
     8761 attcataacg ttcggcaaag cttgttaagg aaatcaattc atgcgggtga ttcaataaat
     8821 actgtgtcat gtcaactaga cgttcactgc gacgtacttt cacctattcc aactcctttt
     8881 aagaaatttt atcgttttac attatataag tttttcttca aaaattcgag cattttatga
     8941 aaaaataaga aaatagttcg gtatttatta aaataaaaag aagcctataa aaaatttttc
     9001 gtttttataa ggcttctttt ctttataatt tagttatttt ttcttctgaa ggcaaccaat
     9061 attcgtttga tgatatttac aatcaggaac aaagcaataa agactaatgt gattgttgct
     9121 cctggaggtg tatctagata aaacgagcta gttagtcctg acagcatccc tagaaatcct
     9181 acacaaacac tgatagcaat cacgacattg aagcttttgc ctaatcgcat accgattgct
     9241 gcgggaagaa ccatgattgc ggatatcaaa agtgcaccgg caatcgggat catcacagca
     9301 atagccacac cagtaatcac attgaacatc atcgacatca aatgaacggg tagcccatcc
     9361 acgtgggcgg tatcttcatc aaaagtcaga acatacatcg gccgtttgaa taaaaagaac
     9421 aatataccga tggcaacgaa taagattcct aaaaagatga cttgctccca tgtaatggtc
     9481 acgatcgaac caaacagata ggattggata cttgttgctg aattccctcc gctcaaattc
     9541 atcaatacta acgctagcgc caaaccacca gccattaaaa tggcaatgga gatttctgaa
     9601 taggttcggt agatcgttcg cagatactcc aatatcacag ctgctaatac aacgactagc
     9661 atggtcgtaa gtgtaggatt aaggttcaaa aagaatccta acgctacccc tgctaaagag
     9721 acatgagaaa gcgtatcagc catcagcgat tgtcttctga tcactaaaaa cacacctagc
     9781 atcggggcga ttccggcaat gaagatagcg gcaagaaacg ctcttctcat gaattcatat
     9841 gaaagcaacg ccattgagaa tcctcctttc tcaccagtcg gatctgtctg tccgcatact
     9901 gtttgatatc ttcatgatca tgggtgatca ttagaactga tttcccatgg acatgcgcac
     9961 tatgtcggag aagacgataa aattcatttc tggattcttc atccatacct gttgttggtt
    10021 catcaagaac aaataagtca gggtcagtag caaaaatacg cgctaaactg attcgctgct
    10081 tttgtccgcc agacaattca cctattcgcc gatttcgcat atcccacatc cctacagctt
    10141 ctaaagcacg ctgtacatgt tgatgatctt tttcagagag acgcttgaac cagcggcctc
    10201 ttggatatct tcctgaacgg actaattcga tcaccgtact aggaaaacct gcattgaaag
    10261 atgcaacttg ttgaggaata taaccgatac ttaatttttt tccttcttga tttttctcag
    10321 caatctttat cattcctttt gaaggtttca gtaatcctaa cgatgctttc accaaggttg
    10381 acttggctgc tccattttct ccagttaaaa tgacaaattc acccgcatct acatgataag
    10441 agacatcttc tagtacaggt tcatcatcat agtaaaaggt caaatcagat atttcgatat
    10501 aacgcacctt acaacctcca ttctaaaact taattgatac tttcttttaa agctttcaga
    10561 tttttttcca tgacagaaat ataattttcg cctgctttga tttgttcatt agtcaagctt
    10621 tctaaaggat tcaacacttc tagcttcact cctgtttcat tcgacaatgt ctcagctacc
    10681 ttcgaagagg cattttcttc aaaataaatc actttgatgt tgtttttctt cacaaattct
    10741 tttagctcag ctaagcgact tggtgtgggt tcctgatctg gtgaaacgcc cgaaatcgct
    10801 acttgtttta agtcgtattg attcgctaaa taagcaaaag cagcatgctg agtgacaaat
    10861 gtgcggtttg ttgcatcttt tagctcatcg gagtattttt gatccagtgc ttcaagcttt
    10921 ttgatataag catcggcatt cttcgtaaaa gtttcctttt tatctggata tttttcgcct
    10981 aattcttcag caatcgttct gacttctttt atagctaata ccggatcgag ccaaacatgt
    11041 ggatcgtatt catgtgaatg accatgccct tcttctgatt cttcatgttc gtctgcttct
    11101 tgcgattcta aacggtcgat tcctttagct gcttcgatca tcaaggtctg tttgctatcc
    11161 actgaatcct ttaacgaatc cacaaaaaat tccatgtctg aactattata cacgaaaaca
    11221 tctgcatcgg aaatttctgc tctttctttt gcacttggtt cgaaatcatg cggctccgtt
    11281 ccagcaggga tcaaaagttt cacgtttcct tcatccccta cgatctcttt tgtaaaatca
    11341 tacatcggat aaaaagtcgt aacgatcgtc aaatcctctt ttttgtctgc ttccttgttc
    11401 gtatttccac atgctgcaaa cagtaaagca cctatcatta ccgtagctgt caaaagatat
    11461 tttttcattt atatgctcct ttcaatgaac aaatcggaat tttacgattt attaacgtga
    11521 actaatgtat caaaataaaa aaacacagtc aatagaaatc catcaatttc tgatttaagc
    11581 atgtatattc ttgattaaat cgtaaaatgg atgagttgct gctcatatct agccatttca
    11641 ctacaataaa aaactgaaga ataccatttt aggattcctc agtttttcat cacctatttt
    11701 acttcttata ttttattgca gggttcgtac taaataaact tcctcacaaa aaccttttaa
    11761 cccattatat actctctgcg ctcttgaata atgttgacac aaggcaaaaa cggttggtcc
    11821 gcttccactc atcaatgcag catctgctcc gtacttgatc atacgctctt tgatttgatg
    11881 gatgactgga tgccgctttc ccgttatatc ttctaaactg tttcccattt ttttgatcat
    11941 ctgctgataa tcttgctctc ggatggcttc agcaagtccg tggatgtctt gatgttggat
    12001 ggcttgcgta tctacttctc taaacactgt acgtgtagag acactcattc ttggtttgac
    12061 caacacaacc cagcactgtg gcatagaagg taatacttgg atttcttccc ctttgccacc
    12121 gacaaatgcc gtacttccgt agacacagta aggaacatct gtaccgactt ccaaaccgat
    12181 ttctgccagt tcttctaacg aacagcccag attccataat tggttgatcc ctcttagagc
    12241 agctgcacag tctgtacttc ctccgcctaa tccagctgct actggaatat tcttcttaac
    12301 aaagatcttg acaccggttt tgatattgta tttatttttt agcaataaag cagcttgata
    12361 aacattgttc cgttcatcta ccggtaaaaa tgctttattt gtttctacaa tgattttgtc
    12421 ttctgttatt tcttcaaaaa atagatgatc tgccaagtct acgctcgaca tcaccatttc
    12481 caactcatga tacccatctt gccgtctata taatacatcc agtcctaaat ttatcttggc
    12541 tggcgctttt tcaatcaatt ccatcctctc acccattcga aaagtctaag tcgcaagtat
    12601 tctatcatag ggaaaaataa aagtatagct tatgtctgcc tagtggttga ttttgtcatc
    12661 gtttcaacag ctttcacaga attttctctt cataatccaa acaagttcta gtgattctta
    12721 taattctgtg agcacttctt ctgccaaact cggaacattt cctttttctt ttcctatcag
    12781 actgagtagc tgcatggtag caaatccgaa attacttcct ttcctataag caaaataacg
    12841 tccttcccaa tgatcgacat attttaattt cttttcataa gcagactgga aggaatagaa
    12901 aaaattacca taattatata cgatatgcat gactttttct tgaaagaaag aaaaatctgt
    12961 ttctccaaca ttagctaatg gagctaagcc tagattggct tccgagtagc ccattttctc
    13021 gtatacaata aacagattgg ctaacagata gtcagctaat tcctcagatt ctttaggtaa
    13081 gacccgcaac aaatcatatc ccgcctgctt cttcgtcatc ggctgagcgg tgatgaagcc
    13141 aacgactttt tgatctttac ggacaatacc gacaccgcta gataatacat atgatttatc
    13201 aaatcgtccc acagagaagt atttttctcg tgcaccttga agccattttt gtgaaacttc
    13261 atttacagct tgatgtaatt cttccggcag ttgatcgtac caagtaaaat ggtatccttc
    13321 tttcatcaaa cgttgatatt caagttgctg actcagccga gacaagtctt ctgttgctag
    13381 atcaacaatc cctgcttcac ctactttcgt gaagtgaaaa cccaattcat gaagcatcac
    13441 tacgtagctt tctgatatct tataaaacgc aagctgatag cctaaacaat ctgcttgttt
    13501 cataaactga ttcgttgctg cccgcatcat tttaggattg ccaactggat ctcctaaaac
    13561 aaagcatttg tttcctttga tctgataacc aaaaacgact tgatcttggt cgtcttcttg
    13621 gtaataaaaa taactgtaac ctgacaagcg aagctgatgg cttgtagctg tgcctccgta
    13681 tgtttccaat aaacggtcaa aacggtcttt ttcgtactca ctgccaagct tcgtagtatc
    13741 ttcagctaaa tattgataaa gcgccactaa agctagcaat gagatgccca aaccaataag
    13801 ccctgagaac cacacatcat ctgaaggaaa caaaataaaa tgatttcctg ttattcgacc
    13861 gactaaaaag cgtccgctgt gatagcctgc aattgcgtaa acgataaaca aaaagccgaa
    13921 caagctagca tcaaagatta tagctcccca agaataaacg aattttgttc gataaaattc
    13981 ttttctggat aaccacacag ctaacagaat caagacatat accaatatca actgccaaga
    14041 taacgtacgt gtgattgtat ttaaaatacc aaaagatagt aaagcaatcg taggcagaaa
    14101 tgcctttttg acttttactg aaagtgctct agcaaggccg agtaataaaa agccaaccaa
    14161 tagattcact gtctgatcta aaaaattgaa tgagaacggc aataatactt gaaatagccg
    14221 actgattgca gacagattag tgattgttga tagaagtacc atcatgatcc ccgcaaaata
    14281 gacagcactt acgagcacga tatgcgcaac cttttggaaa aacagtcgcg gaatgttatc
    14341 taaaaatcga ttgattttga ctcctgtatg tgtgatgaac aatagaagtc ccgtcataaa
    14401 aggtagaaca taataaaaca accgataata taatagccaa actactgcta catcttgccg
    14461 aacaggcaat tgactcattc ctaagatcat caaaacgtca aaagtcccca ttccacctgg
    14521 gaccatcgtc agcattccta tcaatgtagc aatcatgaac ataggataga tcgaaagcat
    14581 cgaaatatct attctcatca acttgccgat gatcaaaaat accgcaaggg ctcccgtcca
    14641 ttgtccaaag gatgccagta gcagaccaag caagcctttt ggataaaact cgaagaacaa
    14701 tgtctttctc tttagataag caaaaaagaa aatgactggt gctaaaaaac taccgccgaa
    14761 aagccagatc caatagcttc gaaaaatact ttctgactga ataaaaaaga catcaataaa
    14821 tgtaagaaac gaccatacag acaaaccagt cagcataaat agtgcgactt ttgatacagt
    14881 ggctaaaacc atttttctat ttgtctgctt tccataaaaa ctagcccgca gacttgctcc
    14941 taccacacca ccaaaaccgg cgagattgtt gatcgtgttt gttacccacg cagcaagaag
    15001 aaactctttt ctttccattt ttggttttcc ttgtttttct aagactctga tcgtcaccca
    15061 atcatacaac aacatcggag tgacacccag cagtccagcc agaatcatga gcaggatcgt
    15121 catgcggctt tgttgtccca tcctttgcca aatatcttgc caactcatgc cattagcaat
    15181 atttgcgact tgatttgcca caaagactaa cacggagccg aaaaaaatca gttttaaaat
    15241 cagactatgt tcctttatcc attgcagcat caagtatcgt ttatttttca cattttccca
    15301 ttcctaactt gtatactttt gtgtcatacc ccaatgttat cttatttatt ttaatttttc
    15361 cactttagac ctgttctttg cttgcgatga tagaaaaaga aagatatcct aatgctaaag
    15421 gagaggataa catgaaagta ggatttatcg gcacagggaa tatggcacaa gctattattg
    15481 atggtttatt aaaaaaagga acagtctcga aagaagaggt gttcgtttcc agtggacatt
    15541 ttgaaaatgc acaaaaattt gctgctgaaa ctggcgtcca tgcatgcaaa agtaatcagg
    15601 aagttgcatc acaatcagat atcgttcttt tagccgtgaa accaaaaatc attgaaaaag
    15661 tattggaaga actaagagaa tatagccaga aagtcttatt catttctatt gcttcaggaa
    15721 aatcattaac agatttagaa acagcgcttg aagatcctca ggcctccatc gtacgtgtga
    15781 tgccgaatgt caatgtcagc gtaggagcag gcgtttctgc gatttgcaaa aatgaagctg
    15841 ccacggagga acagcttcag caagctacga tgatttttga agcaatcggc agcgtctatc
    15901 ctttagcaga atcagatttc agtacattca ttggccttgc tggcagctca cccgcattcg
    15961 tttacatgct gatcgatgcg atgggacgga ctggtgtact gaatggtttg tccaaacaga
    16021 cagccactga gattgctgca aaagcaatta tgggttcttg tcaaaaattc ctttcaagtg
    16081 ataaaaatcc atgggaactt gtagaccaag tttcttctcc tggcggtaca actgttgcag
    16141 gtgtagttgc cttagaagaa gcaggattca tcccagcaat catcaaagga atcaatacga
    16201 cgatcgagaa agatcttgag atgttgaata aaaaataatg atagcaatgt tttttcgtgc
    16261 cttacaaaaa aagaagagct gtggcttttg ccgcggctct tcttttgtat tttttattat
    16321 ttagcataat cagttgcacg agtttcccga ataacgatta ctttgatgtg tccaggataa
    16381 tccagttctt cttcgattcg tttacgaata tcacgtacta aacgaacagc gtctaaatcc
    16441 gagatttctt ctggcttgac cattacccga acttcgcgtc cagcttgaac tgcgtaactt
    16501 gattctacac cggcgaagct gttcgaaata ttttccagac ttcttaaacg acggatgtag
    16561 ttttctaatg attcacttcg cgcaccaggt cttgctgctg agagcgcatc tgctgcagct
    16621 acaaggacag agataacaga agtagcttcc acatctccat gatgagaagc gatcgcgttg
    16681 attactactg ggttttcttt gtacttggca gctaattccg caccgatctc aacgtgagat
    16741 ccttcaatct catggtcaag tgctttccca atatcatgga gcaacccggc acgttttgct
    16801 aattggatat cttcgccaag ctctgctgct aagataccag ctaattttgc aacctcgacc
    16861 gaatgcttca agacgttttg tccataacta gttctgaatc gcagacgtcc gatgatcttg
    16921 attagatctg gatgaagtgt atgagcaccg acttcaaacg ctgcctcttc cccgtattcg
    16981 cgaatacgtt catccatttc tttacgagat ttctcgacca tttcttcgat acgcgctgga
    17041 tggattcgtc catcttgtat cagtttttcc aaggtcatcc gtgcgatttc tcttcggatt
    17101 ggatcgaatc cggaaagaac aactgcttcc ggtgtatcat cgatgattaa atcgatacca
    17161 gtcagcgtct caagcgttcg aatattacga ccttctcgtc caatgatacg acctttcatt
    17221 tcatcattcg gaagggtaac gactgaaaca gtcgtttctg aaacttgatc tgctgcgcag
    17281 cgttgaatcg ctaatgataa taagtttttc gctttgcgat ctgcttcttc tttggcacgc
    17341 tgttcagatt cttttaccat tagagttaac tcatgattca gctcttcttc agtcgatttc
    17401 atgatgacat ctcgtgcgtc ctcttttgat aaaccagcaa ttttttctag ttctttttgt
    17461 tgatcttcaa tcattttttc aacgtctttt tctcgctctt caattaattg ctgttttgaa
    17521 ctaagtgctt cttctttact ttcaagtgag ttctcgcgtt tttctaacga gtcatcttta
    17581 cgattcagcg tttgttcgcg ttgaatcaaa cgattctctt gagattttaa ttctaactta
    17641 ctttctctca gctcactttc aacttcagaa cggtatttct gattttcttc cttagcttct
    17701 aacaatgctt ctttttttag agtttctgct tctttttttg cactatcgat gattccagca
    17761 gctgatgatt gtgcaccagc tatttctttc tcgtgacgtg actttgcgac cataaaccct
    17821 aaaccaagac cgacaattaa accgatgata gcgaggagaa tgttgaatac cataaaatcc
    17881 acctccatac tatctttttc atttttatca tctatacagc ttctatgata aattattcta
    17941 aactcgtcaa tatgcatctt cgcatatatg tgtacaaaaa acatgcacaa ctttattcta
    18001 atgtttgtac cccgtagtgt caactttaaa taaacaaaga aacggctttc tacttattca
    18061 ttaaacgatg gtttttaaaa taaatgacac tagtttcata taggtaaacc tttaaattga
    18121 gaaacttttc tattaaatta ttctttgtag atgaacagat atttttattt tatgtaccca
    18181 ctcgtataat taaataactc acgatttctt tattcaataa aaaaacggca ggtcaaggag
    18241 agtacctact cttcagacca gccgtttttg tttatcataa tttttattct tctactaaag
    18301 gcaattcttc ttgtcctttt tcatcttctg ggacagcgac ttcttcacca ataccataag
    18361 ctgctctaac tagagcagaa acttctgcca tcatttcagg atgattagcc atatagattt
    18421 tagcgttttc ccgtccttga ccaatccgat cttctttata agaataccaa gcaccgcttt
    18481 tatcaacaat gtctttttct actgccatgt ctagaagttc tccttcttgt gagatcccta
    18541 aaccatacat gacatctact tcagcgattt tgaaaggagg tgctactttg ttttttacga
    18601 ctttgatctt tgtacggtta ccaacaatat ctgtaccttg tttcaattgt tctgcacgac
    18661 gtacttccaa acggatcgtt gcgtagaatt tcaatgcgcg tcctccagga gtgatttctg
    18721 gattcccaaa catcacgcct actttttcac ggatttggtt gatgaaaata gcgattgttt
    18781 ttgttttgtt gatcgaacca gagagtttac gcaatgcttg agacatcaaa cgtgcttgta
    18841 acccgacatg tgagtcaccc atttcgccgt cgatttctgc tcgtggaact aaagcagcaa
    18901 ctgaatcgac tactacgata tctacagccc cacttgatac taaagcatca gcgatctcta
    18961 gaccttgttc tcctgtgtca ggctgtgaaa gaagtagttc atcgatattc acacctaatt
    19021 tttgtgcata ttgcggatct aacgcatgct cagcatcaat gaaagcggcc gttccgccat
    19081 ttttttgtac ttctgcaata gcgtgtagtg caactgttgt tttacctgaa ctttcaggtc
    19141 catatacttc gatgatacgt ccacgggggt aaccgccgac acctaaagcg acatctaacg
    19201 caagagagcc acttggaatt gtagagattt gttggtcgat tttttcgccc aatttcataa
    19261 tagagccttt accatagctc ttttcaattt ttttcagtgc agcatctaag gctgctttac
    19321 gatcatctgc caatacgata atcctcctta tatttacaaa tcagagcaac atttcattat
    19381 ccttatcata tcttttttag tgaaaaaaag caagaaaaaa ccgaacaaat attcgcattt
    19441 atcattttct taaaagctgt tttctcaaaa gatcaaatcc ttgcataacc gcattatatc
    19501 tgatagcagc acgatctctg gcaaagtgat atttttccga aaccacgccg tctttagatg
    19561 aaatagcgat ccatactgtt cctgcagatt gaccttctaa cgtgtccggt ccagccactc
    19621 cggtgaaagc tacactgtaa tctgttcttg ctatctcacg tgcttgaatg gccatctgct
    19681 ccacacattc tttgctgact gttccatatt ctgctaatag ctccggatca atctccagaa
    19741 aaccagcttt tgtttggagc gagtaggtaa cgaatccgcc tggaaatact tcagatacac
    19801 cagcaatgtc gcctaatgcg gcttggaagg cgccggctgt caaactttcc gctgctgtta
    19861 cagtctgctt gttttctttc agtagttcca ctacgacttt tgctagcgaa ttatcatcgc
    19921 cgtatccata aaaatattcc cctactcgtt cttggatttt ttcttctaat gctaaaagag
    19981 cttgattccc tgcctgaaca tcatttgttt tcactgtcag tcgtaatgtc acttcatttg
    20041 gtttggcata tggtgcgatc gttggattga tctgtgtctc aatcagatct tttagctcag
    20101 tgaccagtcg cgattcacca atcccataaa agcgcaaaac tttagaaatt agtttttctt
    20161 cagaaggaaa acgttcctct agtaaaggac gtacttgttc cacaaacatt ggtttcaact
    20221 cattaggcgg accgggaaga aggatatacg catgtgtatc tgtttgataa aaagtcccta
    20281 aagcaagccc tgtacgattt ggtagaggaa ccccgccttc gataatctgg gactgttgca
    20341 gattgttttt ggtcattttt cgatgggttg tttcaaaata tgccaataat tttttgtatc
    20401 cttccgtatt ttgtatgaga gacttaccga ggtgagccgc agttgcttct tttgtcaggt
    20461 catcttctgt cggtcctaat ccgccacata agagtatgag ttcacttctt gtttcagcta
    20521 gagcaatcaa ctcttctaaa cgctgctgat tatctcctac aactgtttga taataaactt
    20581 cgatacctag atcagctagc tgttctgaca agaaagtggc attcgtattc acgacttgtc
    20641 ctagtaaaag ttctgttccg acagctatta tttctgcttt cattacttcc cgctccctta
    20701 tatagtatac gctgtatttt tatatttttt tatttaaaaa gagggcaagg agctgtgaca
    20761 aaaatcttgt cacagctcct tgttccaaat aaacagtgtt ctcctgccaa aacctcggtc
    20821 ataagtcaca atatacataa aacatgaaaa gctgtttttt gaaattatcc cttgtgactc
    20881 agagttagac ggcaggctca caacctctcc actaaacgat acttacattg atcctttgaa
    20941 cacaccgctg tttttgatga agtaatccac acctgaatag atagtaaaga tcagacaagc
    21001 ataaagcatg atttgatcta ctggaatacc gatcaggctg aatgggatat tattgataaa
    21061 cagcaagata atagcaacca tttgtgtagc cgtcttgact tttcccggcc aagctgcagc
    21121 catgacttct ccatgttcga caagtagtaa acgcaagcct gtgacggcta attcacgaca
    21181 gacaatgatc gctactaccc aaccaggggc ctttccttgg tcaaccaaca tgataaaagc
    21241 agtcataact agcattttat ctgccaacgg gtccgcaaac ttgccaaaat tagtgacaag
    21301 gcctcgcgca cgggcaattt ttccatctaa ccagtctgtg atactagcta aagcaaaaat
    21361 aactgcacct actagctgtg tgacagccag tgtggtgtct cctacgttaa attgtcccca
    21421 atctaaaggt aaacctacaa ccaaaatgaa aatcgggatc atacaaattc taagtacagt
    21481 taatttattt ggtaaattca cactatcgac tcctttcttc cctattctac gtgactatca
    21541 gcgaagtttc caccgatatt atttactttt ccaaatgaat ttattcaaag gagtattttt
    21601 attgaaattg atctttttga attaacgaag aaggaccgcg acacagattt gtcacgatcc
    21661 ttctttttta tacctacaag taaacagatg cgtaaactaa tttatacgat cattctgcgt
    21721 attgaagagt aaggttcaca ttttttggac tctgattgtt ttcccctgga ttaactggta
    21781 cggattctcc attcgctttg atcgttgcat tgcttgctgc accaatcgtg atggtcgcat
    21841 ttgttgctgt ttccggtaac acggtactct gtgtttcatt tgctgccagt gtcccttgat
    21901 aaacataggc attgtctact agcacaccta accatacacg attgacagca gtaaattcaa
    21961 gggttacagg cttggtagcg tctgtgatat ttactgcgat ggcactgcca gaatcttctc
    22021 ctgtagctat tgccattttc ttttcttcac ttgattttgt tgttgattct actgtagaag
    22081 actctttggt ctgcgtgctt tgctctgagg aagaggactc ctcgactgat ccttctactt
    22141 taagcgaaga agctgtgtct ccgattattg gatcagcttg acgatcttgc caagtcatat
    22201 agcccacgac aacgacaatc gccaaagcaa ccaatcctaa taaaatgaca ggaagacttg
    22261 tccaaaagcg acttggatgc gattcttcct gatgcattgc ttttctagaa gtacttactg
    22321 tttcaggctg cggacgttca gggaccgatc ctgtcaattt gcttttccca tcaaaaacat
    22381 cgactaaatg gtctccatct tctcctacag cttcagcgta ttgccgaata aatgcccgca
    22441 cgtaaaattt accaggcaat tggtcaaaat catcattgtc gattgcttcc aaataacgtt
    22501 tttgaatttt tgtaatctgc tgtaattcat ctaaagatat ttttttattc aggcgtgctt
    22561 gccgtaattt ttctccgatg gtttcaaaag ccactcgttc atcttctcca gtctgtttga
    22621 ttctccgaag catctgctgt tgcaacgaaa gacgttatgt ttgggtgctg tgacaaaagt
    22681 catgtcacag ctcctttttt ccgaataaac attgttctcc tgccaactcc tcggtcacaa
    22741 gtcacaatat ccaataaata taagaagctg ttttttgaac ttgttccttg tgactcggag
    22801 ttaaacggca ggctcacgac ctctttctta aacggtgttc aatcagctgt tcctcggtat
    22861 tagctcaaaa accggcaaaa tataaggaga tatttttccg t
//
LOCUS       DADGHT010000042        22634 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.042, whole genome shotgun sequence.
ACCESSION   DADGHT010000042 DADGHT010000000
VERSION     DADGHT010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.042"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(228..1115)
                     /locus_tag="JX887_001467"
     CDS             complement(228..1115)
                     /locus_tag="JX887_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1257462.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1112..1981)
                     /locus_tag="JX887_001468"
     CDS             complement(1112..1981)
                     /locus_tag="JX887_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1257463.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2118..3404)
                     /locus_tag="JX887_001469"
     CDS             complement(2118..3404)
                     /locus_tag="JX887_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1257464.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3677..4255
                     /locus_tag="JX887_001470"
     CDS             3677..4255
                     /locus_tag="JX887_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAX1257465.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4255..5184
                     /locus_tag="JX887_001471"
     CDS             4255..5184
                     /locus_tag="JX887_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1257466.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5181..6917
                     /locus_tag="JX887_001472"
     CDS             5181..6917
                     /locus_tag="JX887_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1257467.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6980..7816)
                     /gene="pheA"
                     /locus_tag="JX887_001473"
     CDS             complement(6980..7816)
                     /gene="pheA"
                     /locus_tag="JX887_001473"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAX1257468.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7813..8322)
                     /locus_tag="JX887_001474"
     CDS             complement(7813..8322)
                     /locus_tag="JX887_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAX1257469.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8315..9610)
                     /gene="aroA"
                     /locus_tag="JX887_001475"
     CDS             complement(8315..9610)
                     /gene="aroA"
                     /locus_tag="JX887_001475"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAX1257470.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9623..10714)
                     /locus_tag="JX887_001476"
     CDS             complement(9623..10714)
                     /locus_tag="JX887_001476"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAX1257471.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10731..11897)
                     /gene="aroC"
                     /locus_tag="JX887_001477"
     CDS             complement(10731..11897)
                     /gene="aroC"
                     /locus_tag="JX887_001477"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAX1257472.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11899..12963)
                     /gene="aroB"
                     /locus_tag="JX887_001478"
     CDS             complement(11899..12963)
                     /gene="aroB"
                     /locus_tag="JX887_001478"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAX1257473.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12996..14018)
                     /gene="aroF"
                     /locus_tag="JX887_001479"
     CDS             complement(12996..14018)
                     /gene="aroF"
                     /locus_tag="JX887_001479"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAX1257474.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14677..15651)
                     /locus_tag="JX887_001480"
     CDS             complement(14677..15651)
                     /locus_tag="JX887_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAX1257475.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15632..17515)
                     /locus_tag="JX887_001481"
     CDS             complement(15632..17515)
                     /locus_tag="JX887_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAX1257476.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17533..19758)
                     /locus_tag="JX887_001482"
     CDS             complement(17533..19758)
                     /locus_tag="JX887_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAX1257477.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19873..20907
                     /locus_tag="JX887_001483"
     CDS             19873..20907
                     /locus_tag="JX887_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1257478.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20974..21987)
                     /locus_tag="JX887_001484"
     CDS             complement(20974..21987)
                     /locus_tag="JX887_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1257479.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22065..22253)
                     /locus_tag="JX887_001485"
     CDS             complement(22065..22253)
                     /locus_tag="JX887_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAX1257480.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         6446 a         4863 c         4096 g         7229 t
ORIGIN      
        1 tgacaatcag gacagtcatc ggcaatatag cagcaatcac ttctttaaaa ttttttagca
       61 tgtatcctcc tcctttactc tttaagttta ccttaaaatg aaagagtttt cgagcacaaa
      121 cttaaaacgt tatcatttaa tttttctcaa cataaaataa cacacgtccc aaaagtatct
      181 ttttacttgg aaaaatgact ttgaaggaac gcgcttattg tgttttttta ttttacagag
      241 ccgatcattc cttgaacgaa ttgcttttgc aaaacaaaaa atacgatggc agttggtaaa
      301 gtagcgatga ctaatccagc catgatcatt ccatagtctg gtgtatagga agcacccata
      361 gcagataaaa caagcggaac cgtccgttta tcaggagatt gcaaagctac taagggccat
      421 aaataattgt tccagctact catgaatgtg atgattgcag ccgcggcata ggtattttta
      481 gccgtcggca tatacactct aaaaaaaata cttagttctt ttagaccgtc taatcgagcg
      541 gcttctacta gatcttttgg aaaagattta acattttgtc gaaagaagaa gatcaaaaaa
      601 gcagtgctaa cagatggcag gatgacaacc aagaaactgt tgattcccaa aaccgttccg
      661 ttcaattgtg aaaacattcg atataaaggg atcatcaatg ccgcaaaagg aaccatcatc
      721 gatagcagta gaatattgaa aattaggtct tttcgtttac tttgataaat ctcaaatcca
      781 tatcctgcca ttgacgaaat cagcaatgca aacacagtgg tcaccaaagc gatcatcgct
      841 gaattccaaa gggaacgagt aaaattcagc tcattggaaa acaaattttg aaaattgatg
      901 atcaagttac tgccaatctt tatttttccc gatgtgatat ccacgggtgt attcgtcatt
      961 cccaaaacca tccagacaaa agggaaaatg gaaataaatg ataggatgct taatgctgta
     1021 tactttaata ctgacccaat tgtcgaacga agttctaatg cttgtttttt gacgttgggg
     1081 cgttcgattg tttctttttc taccatattt ttcatcgact ttctcctcct actttcgttt
     1141 ggattatcga caatatcaca ataaaggaaa caataacaaa ggaaactgct gccgcatatc
     1201 caaaattagg cgtgaattta taactcaaat tatagatgta ttgagatagg gtggtcgttg
     1261 catttgctgg tcccccgcca gtaatatttt gtacttcatc aaaaagctgc aatgtcccga
     1321 tcgtcgaagt aatggaagta aacaaaatga ttggttttaa atttgggatc gtcactttga
     1381 taaactgctg ccatttagaa gcaccgtcaa tagatgctgc ttcataaatc tccgaatcaa
     1441 tattttgcat gcctgaaagg aaaaaaatca tattgtatcc agtccaacgc caagtgatcg
     1501 aaagaatgat cagaactctc gcccaaattg gatgagtcaa ccagccaatc ggtgtgtcaa
     1561 tcataccaat gcccaacaac aagttgttta caaggccaga ttgagaaaat agacttttca
     1621 tgatcagaga ataactgacc atcgaagtga tacatggaag aaagatagcg gttcgaaaca
     1681 accctttata tttcaacttt ttatcattta aaaggttgga aataaaaagt gctagaaaca
     1741 acatgatcgg tacttgtaca agtaaataca ggaatgtatt aaaaaaagct tttttaaaag
     1801 ttgcatctgt caacatccgc tgataattac ctaacccgtt aaatgtcata ttgacagggg
     1861 gaccactttg aaaagacgtg atcaaagcca aaaccatcgg aataaaaacc atgattgata
     1921 tcaaaatgac tggcaagatt aaaaaagcat gcccgttttt gaataaatct ttctgcttca
     1981 ttcttttccc tccaattcta tcattgatta tctacatgaa aagacaagaa agacaatatc
     2041 tgtaaggcag acgtgatctt ttttgtcttt tcgtttgtct gatgaaaaag cgaagaaatt
     2101 cactttttta ccaccgatca attagccaat tgtgcttcta cttgtttttg tgtatctgct
     2161 agtaccttgt ctgtctcttc tccattgatg attcgatgaa gagcttcagc tacgactgct
     2221 tcaattgcat aggtctcatg tccgtaattc acttctggta tttcagatgt ccatgttgaa
     2281 aaatcgtcaa agatcttttg accactgtaa aattcagaag cttcttgata agcttcttgt
     2341 tcattcgcgc taagcatcgt agatactagt ccgatttctt tcgcaagagt gcccatcagt
     2401 tcttcattcg aagcaaacgt tgcttctagg aaatctttcg ctgaatcttc tccagctact
     2461 cctttgatca cataccagcc agcgccgcca aggttagaag cttgcgcttt ttgcagattt
     2521 tctggaagtg caggtattgg tgcaatcttc cattttccag attggttttc tgctccttgg
     2581 atcgttgaag aataccaagc gccagttggg ctagaagcta ctgctcctga ttgtatcgca
     2641 gttactccag cattccagtc agaggtttgt tcgactagat cttctttcaa aagagtggca
     2701 aacaattcaa gaccatactt taaagatgca ttgtcttgga tcgtgactgt ctccccatct
     2761 tcagatgtat accattctcc tgcctgttgc ataatcatcc ttactcgacc aaggtcagaa
     2821 ggattgactt cagcgatttt ctttcccgtc ttttctttga catctcgcgc tacttgaata
     2881 tactcgtccc acttcagatt ctccatatcc tcttctgtat aacctgcttc tgccatcaga
     2941 tccgtacgat agaagtttgc tgttacgccc gaatcgaaag gaacaccgta tattttatct
     3001 cctactttgt ttaccgcaaa tttatacggt gcaaaatgat cttcctttac aatagcagac
     3061 aaattagcga atgcatctgg ataagaagtc aaatagcctt gtatcctata atcttcaatc
     3121 aagacgatat tgggcaatcc ttctgtattc ccgctcgcta aagcggtgtt cagtttctga
     3181 acgatatcat cctgagacat cgtaacaact tctatctctg tttcttcgtt ctcataaact
     3241 ttttttgctt cattcactgc tttgatattg aatgtctcat cccacgccca gacagtgact
     3301 ttttcttctt tgtctgctgt actactagca cttccgcatc ctgttaagaa acctgatgct
     3361 gccgctaaac aaacgactcc agcaattaac tttctgatgt tcatttttat ccgctccttt
     3421 tccatccatt agttgtttac gtttgctaca ttcatcatac caaaatttga aaacggtttc
     3481 tttattattc agatacttca aaaatttctc ctaaaataat aaaaaaatac aaatcaacta
     3541 tgacaaaagg aataatctta gcatctagac caaagatcga aatggtgagg tttctttaaa
     3601 ataaaaatat ccttgcattt tctcctagaa ataagtattt ttaaattaca agactattct
     3661 taaggcgggt aaaaaaatgc caatacgcgt aattcttatc gatgatgaac agacgatttt
     3721 agatggaatg aaacagttga tcaattggtc tgagcacggg tttcaattaa tagggacttt
     3781 ttccagtccg ctgaaagcgc ttgatttttc tttggtacat gcaatcgata tcgtggtcac
     3841 agatgtaatg atgcctgaat taaatggaat cgaattatcg cggctattaa aacagcaaca
     3901 acctgaaaca cagatcctta tcctctctag ctatgatgaa tttgatatgg ttaaagattc
     3961 ttttaaagaa ggcgtcgctg attatctttt aaagcctcga ttgagtcctg atttttttct
     4021 aaattcctta actgccgttt cacaaaaaat caaaaaaaag cccaacaaaa gcccaatcac
     4081 caatcgttat gagcagatct gcgagaatct ttcacagcag attgctggac aaactcgtcc
     4141 attgcttgac cctcttcttt ttgaacacac cttgtttttc tgttatatac cgaaaaacgg
     4201 ccattcagtt caaaacaagg ctctaaacaa aaacagtcga tcacccattc attgatggat
     4261 agcgacgatt cgtttactat ttatcctgtt tctacctttt cggaagaatc cggctatgta
     4321 atcaatactg attccaaaga tacacttagg aagtttgttc aaaagtttcg tcaagaagtt
     4381 tttccaggtg atttttttgt tgtttctgat tcttttgcaa tccaagatat caatgaaata
     4441 ttccaagaga tcagaaattg caccaaagga caacgtttct atcataaggg aaagaacctt
     4501 gcttatcagc atgaacttct tccgttatta accaaccacg agcagcaagc aagtagttat
     4561 ttaacaaaaa tcgttcataa agactacgct ttagctgtca aagaacttga gaatttcttc
     4621 acgacgatat tggaacagcc tattgatcca gcttatttga aacatgaggc aatcaatcgt
     4681 ttctatgcat tactcaacgc tttggctgac gagcatgttg ggaatgaaga actttctttg
     4741 ctcaagatcg cccttccttc tttattagcc gatgctgagt atttcgaaga tttttctatt
     4801 cttgtcaaag aaacacttga gaaactcacc cacttttctg caaatgcaaa aaaagacaat
     4861 ttcgatatct tgactttgat ctacgagttc gtccaggaaa attatgagaa agaaatcaat
     4921 ttacaacttt tatccgaaaa atatcatttt tcatatagct atctctcagc catctttact
     4981 gaaaaatttg gtatcaactt ttcaaaatat ctaaaaaaag tccgtatcag taaagccaag
     5041 ctctttttga cggaaacacg gcttactttg acggaaatct gtgagaaagt cggctatacc
     5101 gaactgggtt atttctccag agtttttaaa gaagagacag gaatgacacc ttctcaatac
     5161 cgtaaaggaa cttttgtaaa atgagaaaaa aaatcaaaga gcatgaactc tttgccaaac
     5221 ttctgttcat tttgttcatc ggtctttttc tgcaagccat cgtcatttct ttgtttattt
     5281 atcatcgatc aagggatgcc tatatccagc tgttcaatca atcgaatgat gtggtactaa
     5341 aaaagattca atctgaattt gaaagtttga atgatacaat cgagaataca ttagccgctt
     5401 ttgattctaa tccagctgtc aaaagctatt tttccaatga tccagcccaa catatggaac
     5461 agcttcagca actaagaaca atccaaaaaa tgaatgactc tctttcaaaa atccatccaa
     5521 tgatcgatta cgatgtattg atctttggag aaaatggaag aacttttgtc ggaaacgaca
     5581 tgctcactgc cgtatctgcc gattcttttt ttcaatctgc gattgctcag agagtgaatg
     5641 aacgtgctgc tgatacacaa atgctttttg cacaccacgg attgactctt cgcgataaga
     5701 aagcacccag cgtcttcttt gtcaaaaaac tgaaaaatac attgaatcac gtttacggat
     5761 atgctgtttt atcgatctca tccaagcaac tagcgaatct ttttcaatct gtagtaaatc
     5821 ctgagatatc gaagatctcc ttcatgaacg aagaacagac gatcatcgca tcaaatgaag
     5881 aaaatacaat tgggagccga tcaatgattt tcaaaaaact aacagtaggt gaaacaacga
     5941 tttcaaatgg acagcagttg acccgtcttc ctctgtaccg ccaggattgt acattactca
     6001 gtcaagtcga tcttcattct ttatctaacc aaatgggcgt gatttttccg attattttgt
     6061 ataatatcgt gacacttgct tttgctggct cattggtatt tatgtatttg gatcgacaca
     6121 caaaatcgat ctaccgcttg attgattcgc taaaacggct agaggaagat ggcttaaaag
     6181 ctactgttcc tgtacaagga agccatgaag tccaattgct agggaatacg atcaatcaat
     6241 tgctaagtaa tgctcagcat cattatgaac agacgatcca agacgaaaag aagaaacgtt
     6301 cgcttgaaat ccaaactatg caagcacaga tacagcccca ttttatttat aatacgctga
     6361 ctagcttgaa atttttgatt tggcagaaaa aaacagatga agcagttcaa ggaatcgaca
     6421 gtttcattac tttactaaga agtacgattg ggaaaaaaga agaagtgatt ccagtcaagg
     6481 aagaaatcaa aagcgtacaa agttacatcg atcttttgag tatgcgatat ggcgaaagaa
     6541 tctcggctaa aataatgatt cctgatgaac tgcagtcatt atctatgccg aatatgatcc
     6601 ttcaaccaat tatcgaaaac gcctatcttc atgcttttca caataaaacg caaggattca
     6661 tcacggtgta cggcaaaaca aaaaatcagc ttcttttatt cgaagtgatt gataacggcg
     6721 atggcttcga tactgaaaat accaaacaaa aaaatgatca tttttcagga atcggcatca
     6781 gccatgtaga tgagcggata cgcctaatgt atggcgatgc atatggctta acgatccaat
     6841 cagtgattgg gacaggaacg actgtaacga tttgtctacc gcttcttcct aaaaatcaat
     6901 cagaatatca aaaataaaga atagccaagc gctgattttt ttattttaag ttaaataaat
     6961 caatcagtat tcttgacttt catctacgcg tctcttctac tgtcagcact ggataacagc
     7021 ccaatatttg actttctcct ccgagcatct tgatttcttg gagcgcattc tctactaatg
     7081 tcattggacg gtccaacaac aaatcgatca cgaaaaaata ttctcccaag ctagttttca
     7141 atggtcggga ttcaatctta cttaagttga tttcccgcca gccaaaagct gccagcattt
     7201 tatgaagcat ccctggccga ttagcaggta gtgtcaagat gacactcatt tttactggag
     7261 ctgactgctg gctggtcatc tttcggtcac cgacgatcca aaaacgtgtc tggttcaact
     7321 cattatcttg gatattctca gctaagatct ccaatccaac atgctgtgct gtttctaatg
     7381 aagcaatcgc tgctgcgtct tctttcggat gttctgctac atacattgct gcagcagttg
     7441 ttgattctgt tgctactaaa ggaacattag gataatgcgt ttctaaaaac tgttgtgatt
     7501 gtgctagtgc ttgtggatgt gaaaggattt ttgtaatctt tgttgctgga ttgcctaaaa
     7561 gctgctgctt gataggaaga acgatttcac ttttaacttc gacttctgga tgtttggaaa
     7621 gaagatcgat tgtgtgatga acagctcctt ccaatgaatt ctctacagga acgacagcca
     7681 gatcgacttg tttgcgaaac aaagcgcgca aacaaacagg gatggaagca tacgcagtca
     7741 attgttctgt aggaaatagc tgacaagccg cctgataagt gaatgaactt tctggcccta
     7801 gatagctgac gttcatatgc ttttgatcct ttctataatg gtatcgatga tcttttctgg
     7861 tgtttgattg gtcgtgttga ttcgatgtgt cgcactttct tcataccaag aaagtcgttg
     7921 tgccaataat gcttttattt cttctcttgt ttttccaaga gctaaaggtc gaatagacgt
     7981 ttcatcttgt tggatacgat caactagaca gtccgcttct gcctctaagt aaagaacaat
     8041 cggctgtgtt tttaaaaaac gccgattttc tgcactttgg acaatccctc caccagtcgc
     8101 gataattttg tcttcatttg acagctttct taaaatatct gactccactt ttcgaaagct
     8161 tttttcaccg taatagtgaa aatattcggc aatcgacaat tggatatgtt cctcaatctt
     8221 tgtatctaaa tctacatact ctttttgtaa acattgagct aaccctttac cgattgttgt
     8281 ttttccagcg cccatgaaac caatcagcaa aatgctagcc atgagcttct cctcctgaca
     8341 caagttctgc taaatcgtca aaaaatgccg gataagagat tgaaacagct tcagctcctt
     8401 ctagttcgca aggtccatca gctatcaaag cagctacttg cagcatcata ccgattcgat
     8461 gatcgcctct gctggacact tttgcgccat gcagaggtgt cggcccatgg atgatcagac
     8521 cgtctgctgt cgcttttatc tttgctccca ttttctgtaa ttcttctgcc accgcatcaa
     8581 ttctgttggt ttcttttact tttaattctt ctgcgtcttt gatgatcgtg attccttctg
     8641 cttgagtagc cactaaagct agaatgggca attcatcaat cagacgcgga atgatttctc
     8701 caccaatcgt tgctttcttc aaatgactcg tcttgacact taaatcagcc gattggttct
     8761 gttcattgtg attcgtctgg gtaatcgctg cgcccatctc ctccaacaca tctaagatac
     8821 cagttcttgt tggattgacc ccgacatttt ttaacaacag ttggctttcc ggaacaagaa
     8881 gtcctgctgc tagaaagaaa gcagctgatg aaatatcacc tggaacagtt atctgttgac
     8941 cagttaattt ttgcggtccg gtcactatga tcgttttatc ttccactgtg atccttccgc
     9001 caaattgacg aatcatttct tccgtatggt tacgggaacg ttctttttca acgattacgg
     9061 atgtgccttc tgcttgtaat gccgcaaaca gcaaagcaga tttgacttgc gcactggcta
     9121 caggcatatt gtatcggata ggtgataaag agcgggttcc tgtcacagtg attggtagat
     9181 actggtcatt ttcttctcct tgcaagtcag cgcccatctc gcgtaaaggt tccatcactc
     9241 gccccattgg acgtttagac aacgaagcat ccccgaacag agtagtcgta aaaggctgtc
     9301 cagccaaaat acccatcaat aaacgtatgg tcgtaccgga gtttcccatg tcaattgatt
     9361 cggttggttg gacaaatgag tggctaccgc gaccatgaat cttgatcacc tcttcctctt
     9421 cttcgatctc gacacctaat tgttggaagg catgtaaagt actcagacaa tcttctgcgc
     9481 gcaaaaaatt ttgtatagtc gtcgttcctt cagcaattgc tccaaacatg atgctgcgat
     9541 gggaaattga tttatctgct ggtatcctaa cagtccctct taatccatgt atttgttgta
     9601 ataattgcat ttatccagcc tcctatttga tccagcaatg ataactggta ttagacataa
     9661 tgattctttt tgcttgtaac aaatcctgtt ggtttttaaa actgatttgc agtattccta
     9721 aaatatcttc cctggtctct tggatcttca aattaatcaa agaaactccc gcttttccga
     9781 tcagtccagt tacttctgca ataacgccag gttcatctgg cacatcgata aataaatcaa
     9841 aaaaggcagg aatcgcgcct tgcttatgga caggcaactg gtctcgactt tcttttgccc
     9901 gattgaaaaa agaaaagatt tccgattggt tctcagtcat gatccattct gctatttgtg
     9961 tcatttcttg ttgccaatct gccaatcgtt ccaataatat ctgcttattg ctcaacaaaa
    10021 tatctgtcca catgacagga tctgaggaag cgatcctagt gatatctcga aagcctcctg
    10081 ctgccagttg tttggctcgc ggatactctt gattgaattg ttctgcctga ttgactaagc
    10141 cagctgccag aatatgtgga aaatgactta gcattcctgt tatacggtca tgttctcttg
    10201 ctgtaagagt tacatatttt gctttggttc cgcaaaatag ttcttgcagt ttttcaacat
    10261 cttttttcgt cttttccaaa ggtgtaaaga tgtaataggc attttcaaat agtttagcat
    10321 ctgctgcctg tatacctgat ttatgagaac cagccattgg atgtccaccg acaaaccgaa
    10381 gatttttctg ctcagcggat gtcacgactt gctgcttcgt actgctgaca tccgtaatga
    10441 tgacgtgatc agacaagttg attctttcaa ggacatcaag ataagctaag gttgtacgga
    10501 cgggaacggc taataagata acgtctgctt gttctgcacc tgtttcaaaa tcacttgcaa
    10561 cgtaatcaac gatctgctgt tctactgctt gctcacgggt ttttgactga ctatcccaac
    10621 caactactat cagttctgga ttggtctgac gaatacaaag tgccatagaa gcaccaatca
    10681 gtccaagccc cacgataaaa acatgttgtg ccatcttatt tgcccccttt ttagtaatgt
    10741 ttcaagtagt cacggtactc cttcactgca gctttcaact caacaagcga atcacttggg
    10801 aattttgaca atagctctgt cgctaccaca gtggctacaa cattttccgc aacgacgcta
    10861 gctgcaggaa ctgctgtact atccgaacgt tctacacttg ctttgtaagg ttcttttgta
    10921 tcgatatcaa cactttgaag tggcttgtac aatgtaggaa tgggtttcat gaccccgcga
    10981 atgacaagtg gttcgccatt ggtcattccg ccttcgaagc cgcctagatt attggtacgt
    11041 cggaaatagc ctctttcttc ttcccatagg atctcatcca tcacttctga gcctggtaat
    11101 gaaccagaag tgaatccgac cccaaattct acgcctttaa aggcattgat actaaccaca
    11161 gcttgtgcga ttttggcatc tagcttcgtg tcccattgta cgtagcttcc taatccagct
    11221 ggaacgcctc caacgagcac ttctacaatt cctccgatcg tatctccatt tttctttgtc
    11281 tgatcgatca aatcttttat tctttgctca actgctggat caacaactcg tacttctgac
    11341 gcttcagaaa tttctttgat ttcttgaatc gagatatttc caggtatttc tgcttggatt
    11401 ccaccaagac aaatcacgtg tcctgctacg atgatgtcaa gttcttccag aattttcttg
    11461 gcaattgcgc cgattgctac acgcatggtc gtctctcttg cagaggaccg ttcaagcaca
    11521 ttccgaagat ctcgatgatg gtatttcata ccgcctacca aatccgcgtg tcctggacgc
    11581 ggacgtgcaa ctcgccgcag tgattggtct ttttcaggca cttctgctac agacatgaca
    11641 gttgtccaat ttttccaatc tttattttct accactaaag tgacaggtga accaattgtt
    11701 ttgccgtgac ggatgccaga cgtgatccga acacgatctt tttcgatctt catccttcct
    11761 cctctgccgt aaccagcttg tctgcgagcg agttcgtgat tgatttcttc ttctgacaga
    11821 ggtaatcctg ctggtagtcc ttcaataatg gctgttaatt ctggtccatg ggattctccc
    11881 gcagtcatat aacgcatctt acagtcctcc taagtaatct ttgaatgtct ctgtgggaac
    11941 aggaacgatt tttgcttgcc caatcttttc tagcaagatg atattcaatt ggcttcctct
    12001 tgctttctta tcatgggtta tcgcgtggaa taattcatct ggatgactta gatcgtacgt
    12061 aatcggcaga tggaattttt gaagtatcct ttctaaagca gctgtcgatc cagttggaga
    12121 caagccgatt ttttctgcat gagaagtgat ggctaccatt ccaatagcta ctccttctcc
    12181 atgactgact accccatatc ctgctgtatt ttcaattgca tggccaattg tatgaccaaa
    12241 atttaaaata agtcgatttc cttggtcaaa gacatcttct tccactactt ttcgtttgat
    12301 ttccaacgta gcagtaatga ttggaacagc atgttccaga agatcttttt cgtctttcag
    12361 ctcgttcagc tgtttccaaa gcgttgcatc tgctatagct gctgatttga tgatttcagc
    12421 gattccttct cgtaaacgac gtaccggcaa agtttttaga acctcaggat caatcaatac
    12481 accagctggc tggctaaatg ttccgacaag gtttttcgct ttgtttgtat tgactgctgt
    12541 cttcccgcca atactagaat ctacttgtgc aagtagcgta gtcggaattt gaacgaaatg
    12601 gatcccacgc atgaacgtcg aggccacgaa tgctgctaga tcacccacca ttcctccacc
    12661 aagtgcaagt atcccatcgc tgcgggtaaa atcattatct gctaaaaaat cgtataactc
    12721 agctgcttgt tctaaagatt tactggtctc acccgccggt acgattgaaa ggactggttc
    12781 aaaattagct tgtctcaatt ggaacatgat tttttctgca tatagtggag caacgtttgt
    12841 atcagtgatc acagctactt tttgaggtct ccaaatcgtt tgaagccatg atccagcctg
    12901 ttctagtgcg cctttttcaa tatgaatatc gtatttttgg ttatcaacat gtacagtaag
    12961 cattcgtttc acttctttct tttaaaaagc tggaattaat cgagtgtctg aatcttttcc
    13021 attgcttctt tcatgatcgc aacttctttc atcatgcgtg agtaagtctt ttcattcaac
    13081 gattggggac cgtctgacca agcatttgca ggatcaggat ggatctctac gatcatgcca
    13141 tctgctccgc ttgccacacc cgcacgagcc attggtggta caagttccca aattcctgta
    13201 ccatgacttg gatcaacaat cacagggaaa tgagttaatt ttttcatcaa tgggacagca
    13261 cttaaatcaa acgtattacg tgtcgctgtt tcgtaagtcc gaatcccacg ttcgataaaa
    13321 atgacaggag atttgtcttc gactgcaatg tattctgcag cattaagcca ttcattgatc
    13381 gtaccggaaa ttccacgttt caatccaaca ggtttacctg ttttaccgac agcagatagc
    13441 agtttaaaat tttgcatatt acgtgcgcca atctgtagga tatcgctgta ctcagccacc
    13501 atatcgatat gcccttcatc catcacttca gtaatcactt tcattccaaa ttcatcagcc
    13561 gcttgacgga tgtatttcaa tccttcttct tctaaacctt ggaaagcata tggagaagta
    13621 cgtggtttga aggcaccacc tcgcagaatt tttgcgcccc cggctttggc cattcgcgca
    13681 cattctctga tttggtctaa tccttcgata gaacaaggac cagccatcgt cacgaaactg
    13741 ccgtcaccaa tttttactcc gtctacatcc acgactgtat tgccaggatg gaattctcga
    13801 gaagtcaatt tgtatgtgtt taaaatacgc acagcatttt ctactccttc atagcgtgta
    13861 aatgctcctt cttgtaaact tcgcgtatca ccttttagtc caatcactac tcgttctgtt
    13921 ccttgatcga ttgagacttt gaatccttct ttttcgatat gatcgacgac tttttttatt
    13981 tgttcttccg ttgcttcttt tttcataatt actatcattg tttttcccgc tttcttttgt
    14041 ttacttatct atcttggctg attttctcta ctttttcaag gtggttttac attaattcct
    14101 actaaatgac cgtgtcctgt tgttctcatt ttcgctcctt ctttcctact tatgacccag
    14161 ataatcaaca aaaaaagatg tccctgtagg aaattgcctc tacagtgaac atcttcaacg
    14221 agccttaaaa agcgctgcaa aaatataaaa tagccactat agatgaattt ctctacgtgg
    14281 ctgtaagtcg tgtttaaaaa tctttagcca tcatagatac aaacctggtt tgtttgtacc
    14341 cacgaagtca tgaatacaaa cctatctaaa atagctaaag taatacgtat tcagttttgt
    14401 aagttttcta gatttcataa aaaatcgctc caaactgatg taagaattgt acctagtata
    14461 gacataaaaa aatcgactgt caatcatttt tatgaaactt tttttaattt tctgatagtt
    14521 aactttgttt ttcagaaaaa taacaattgg ttttattgaa gaaaatagtc atgaacaaaa
    14581 gtatctgaga acttttttac tctcttgttc atgacatata gaataaagca gctttgtctt
    14641 gtaaactccg tttttcaaat aataatctaa agattgctac tgaataataa agccgatttc
    14701 atggtcctct tcgctgctga ttcggtaagg tgactcaaca tccgctcccc agctattgat
    14761 acccccgact cctcttactt ttgcaaaaat cgtaagaacc gttcgtcttt ctggcggtag
    14821 ttcttctata tgtgttgcct gttccagttc ttctgctttg aatggtaaag cggaaaaagc
    14881 aaatggcgta tcctgctgtt caaatcgcaa cgaaaaatct tcttgatctt tatccgtatt
    14941 atccaacgtt tgatttcttg ttagttctac ccatttcgtt tccatatgca tgccgcattc
    15001 ttggggaaca aggtatgggg aaacggggag tcctgccact ttataaatac cttcgacacc
    15061 accagccatc cgatccggat atgtttcccc tgataggcct tcatactcaa aaaattttgc
    15121 tttcgttggc ataatgaacc ttaaacccaa tgcgggtaat tccggtaatc ctttttgtcc
    15181 ataataatgc atattgacaa gcattttacc ctctccagcg atttggtagg aaattgtcac
    15241 ttgggttttt ggtactgtgt tgatttccag tgtaaaaatg atttcaaccg tttcagcgta
    15301 ttcattactt gaatattgat tatttactgg agcaatcggc aaatcgatct ttttattgtc
    15361 caccagtact tctatttctt tgacttttgg atacaatccg gctcctaacc acataccgga
    15421 tttaaatcca aatccgctac ctctgtcatt atcggtcgtt gctcgccaaa aaactggaag
    15481 tgtttcccgg tatagccatt cttttccgtt tttattgagc gattccagtc cgcctcttgt
    15541 ataagaaaaa atataatgcg tattccccga tttgacacct aatgtacagt cgccgaagac
    15601 gattgcaact ttttccgtat ccatatgact tttatttact gtatttttca taataatatc
    15661 ttacctcctg catggcgggt ttttcttgtc catctgcaaa aacgatccca ttccctgaga
    15721 attcatagtc acttggttta tcgtcaaagt caccgccata gcgcatcact tctctgcctg
    15781 tgattggatc agtcacttgg atcgcctgat ctttaaaatc ccatatatag cctccttggt
    15841 acatttcata acgatcaagc aacgtcatgt aagaatccat tccacctaac gaattcccca
    15901 tgtcatgcat atattcacat aagatgaacg gtttttccgc tttattttca aggtagtcaa
    15961 tgatctcttc tggtggcgca tacatgcagc tttttacatc tgaaatcgaa tcttcgaatg
    16021 ctggatttgg aaaattccct tcataatgga caagtcgatc ggggtctact tttttgaagt
    16081 aatcgttcat ttgtcgaatg ttttcttccg cataagattc atttccaaga gaccaaaaaa
    16141 gaatacttgg atggtttttt aatgtttcga aattcgtttt tgctcgatca agaacagccg
    16201 cctgccactg aggtactgca cctggtacgt tgtaagaagg ctcaaatgcg cccatttttt
    16261 gccatgagcc atgggattcg aggttcgttt ccgccatcac atggattcct gcttggtcgc
    16321 ataaataata ccaagtgatc tggttggggt aatgagatgt ccgtacgccg ttgatctttg
    16381 cattttttat gatagccaaa tctttttcca tatcttctat agtgatggcg cgtccttttt
    16441 tcggatgcca ctcatgtcga tttaccccgt tgataatcat ccgttttcca ttgaagtaga
    16501 tgattttatc tttgatttcg attttacgaa aaccgaagga atagtcaata tactccgtta
    16561 ctcttttttc ttcgtctatc gtctccaatt caagcttata taaattgggc tgaaaatgcc
    16621 cccacagtgc cacattttca aatccatcga tgcgaatcgt catttgctct tttaacggat
    16681 attgctgttg atagatttcc ttcccatcag gatctagtat cgctacattc agctgactgt
    16741 ttttggctac ttgctcaaaa gacaaatcta cttcaagttt gccattttga catttgtcat
    16801 ctaagcgagg tttgatccaa agatcttcta aatggttttg tcctcgagca actaagaaga
    16861 catctctgaa gatcccaaaa aatcggaaaa agtcctgatc ttccaagaat gcagctgtac
    16921 ttcttttgta aacctccaca gctagaatat tttcttcttc caaataaggt gttaaatcaa
    16981 attcagacgg agtgaacgaa tcttcggcat acccgataaa atgaccattc aaccaaataa
    17041 acattgcttg ttctacacca gcaaaatgaa tcgagatttg ttttcccttt agaccttctt
    17101 ctaatcgaaa agtcgtcaaa tacgaaccaa ccggattgtc tttagcagct gaaaagatcc
    17161 cttccgcctc tttctcaggg cttgtcgtga aagggggacg gcgaaataca tgtccctccc
    17221 acggatacat cgtattgatg taatggatct tgtcataatt tgctaattca atatgactag
    17281 gaacagtgat ttcatcaaaa gaacaggcat caaaatcttt tttataaaat gtttttggtc
    17341 gtaccgaagg atttggcgaa taacaaaaac gccatgatcc atttaaagac tgtttaaggg
    17401 aggatgtggt ttctacttct tcccttgttg cataacaaac atgatcgcta tgtgcatttg
    17461 attggttcac tctaaaaact tgtggatcat ctaaccattt tatatttgct ttcatacttt
    17521 tttccttctc tctcataact ttttgaaatg aagcagttct gtttggaaat caccttgaaa
    17581 atcggggaag taaagtccaa ctgtcatcaa ttcggccccc gaaaatatcc gcttcgaggt
    17641 ctgttcctga taaagtgcct catcatctaa ccccatcaga tatacttcat ggaacgctgg
    17701 ttgagctgaa gctagtatcc tccctaaaaa cacaatagct tcatcttgtt taggagacac
    17761 aaacatccat gcggcaatat tttcttcaaa aggactcgcc aaacgataat aatggccata
    17821 ctggatcacc ggacgaatcg tttgatagga tataatttgg tcttttactt gctttttttc
    17881 ttcaggagac agctttgtca aatccagttc ataaccaaaa acagcgctca tagctgtttc
    17941 tcctcttgtt ttcaacgaag tagatctgtc ggtctgatga tttggtacag ctgatacatg
    18001 agctgtgatg gacgaaatcg gataagcaag gcttgttcca tattggattt tcatacgctc
    18061 cactgcatcc gtgttatcac ttgtccatga ctgcggcata taataaataa acccggcatc
    18121 aaaccgtcca cctccaccag aacagccttc ccataagatt tccggataat cagttgtcaa
    18181 atgttcaagt agttcataaa gcccgagcat ataacgatgc gctacttctc cttgtctctg
    18241 tgggtcaagg gtaatcgaat agacatctga aagcgaacgg ttcatatccc atttgatgta
    18301 gtcaagagga atcgtatcta aaatctttct catttgtttc tcaatcgtct gccgaacatc
    18361 taaccttgta aaatccagta catgttgtga tctggaagca gaaggcattc tacctggctc
    18421 ctgcataaga aaatcaggat gtgttcgata cagttcagaa tcaaccgaga tcatttcagg
    18481 ttcaaaccat aaaccaaatt tcaatccttt gctatgagca taatctgcta tttcacgtaa
    18541 tccatttgtc aacttgcctt catactcgaa ccagtctcct aatgaagaat tgtccgcatc
    18601 tctttttcca aaccagccat catctaatac gaacatttcg atgcctagct cctttgcttc
    18661 atcaatgatc gccttgattt tttcactatt gaagtcaaag taagtggctt cccagttatt
    18721 gaccagaatc ggccgttcag caaattgatg acgacctctt gcgattcttt cacgtagcaa
    18781 ctcatggtgg atctgactca ttttgttcaa tccctgactt gagtaagaaa ggatcatttc
    18841 aggtgtttga aaagactggc ctgcattcaa ttcccacgaa aaacgatggc tgttgatccc
    18901 accgacgact ctcaattgat tgatctgatc tttttcaagt tcgaaagaat ggttgccgga
    18961 ataaacaaat tgaagtccga tcgcttctcc agtattttct gtcgtatgat gatgaactaa
    19021 agcaataaag ttattcatat ggtgactgct cgttcctcga cggctttcaa atacttttgt
    19081 tccagataaa acagattgcc gtgaaatctg tctttcattg acatgtgctc ctggcaaagc
    19141 aatgacttca tcaaatcgcc tagtatgggc aaagtctagc tggaaactag ccgctttttc
    19201 tagtttgatt gtttctccgg tttcatttct tatctttaca gatcgtgtga tcactgctct
    19261 atcagtaaat atggtataga acaaatcgaa ataaatcgct gtttctctat ccttaagtga
    19321 aatcaccaac gtttgtgcct ctgacttgtc catcacataa gtttgaggca agccttcgat
    19381 ctctggcttc ccatctgtaa tataatggct gtcatatctc agatccagta agtctgatcc
    19441 attcttgcgc tgaatgatcg atgcgggcgt tcgaaagtcc atgctgccat gagaagagta
    19501 ttcttgcggt agtgtatctt tcgacagaga ccggtcagga tttaagggaa catttcctga
    19561 aaatccacga tctcttcggg gataattttt attgtctttg tactgcttga ctggtttgcc
    19621 aaaataaata tgcgccaata cattgctttc ttctatcttt atcagataag aaagaaatgt
    19681 atttcgtaaa tggaagactc ggctcttttc atcaaataag atgaaatttt tatctgtttt
    19741 tctatgcgta atatccatca tttcactccc aacaaaacgg aaaccgttta ctttttttta
    19801 taattcctgt atactgttta ctaaacaatt ttgtcaataa aaatttttta tttttttgag
    19861 gagtgtgtaa aaatggttgg aattagagat gtcgcacgaa aggcaaatgt ctctcctgct
    19921 acagtttccc gtgtgttgaa taacgatcag acgatccatg tggctcagac tactcggcaa
    19981 cggatagtag aggcagctgc tgcgttggat tatgacatca gtactcgtaa atatatcaaa
    20041 aagagaatgc cttcgattgg tgtgatctct acgatcggca aagcgagcga agaacaggat
    20101 atctattaca aacatttgcg agtagggatg gaagaagaag ctcgacgtct gcatttaggg
    20161 atgaatcgaa tctataatct atctgataat cctaaacaat gggaagatct agatcagtta
    20221 ggtgcggtga tcgttgttgg gactgttacg aaagaatcga ttaccgcctt gttaaaacaa
    20281 aacatgcaaa tagtcgtcgt ggataaccct gacatccagc aagaggtcga tatggtgtat
    20341 gcagatcttg aacggatgac taaaaccgta ctggaattgt tcttagaaaa tggtcataaa
    20401 agaatagcct atatcggggg atataaagtc gatatggatg aattcggtgg gaagcagatt
    20461 tctataaatg aaaagaggat gcgtgcctat cagcatttta tgatcgatca tcacttagaa
    20521 aaatatatgt cttatcatct aggtggctgg acagaaaaac aaggtgaggt acttgcgact
    20581 aatctattag aaaatgaatc ccctcttcct actgccattc ttgtcgggag cgatccaatg
    20641 gcaattggtg tctatcgggc attgaaacaa aaaaatatcc aaattggaga agagattgtt
    20701 gtagcaagct ttgataatat cgagacaatc gcaaacctct cccctggctt gaccagtgtt
    20761 caaatcaatg cgaaatcaat tgggcaagca gctgttcgaa tggcattgga gcgaattgac
    20821 ggtatacggg acgaaccaat cattttgact tatcctgcac gattgattgt tagggaaagt
    20881 tttatcccaa gaacaaaaag gtattgaaag agaggttgtg aaaagccgct tcgtttcttc
    20941 atactcaaaa cgaaacggct ttttcacaac ctcttactta tacttattca caaaatccaa
    21001 tgtctgctgg taacaatttt gcgattcttt tagcgtgtaa tcaaattggt attcatgggt
    21061 aatctctttt tttgtatctg tataaaacaa ggattgcacg ggtaccttta attctgtcaa
    21121 ccgattttct aatgcttgac cttgctcctg gaatgagtat gcatttccgt cagttatata
    21181 cgttggcgga aattccttag aaacatggtc agccacacta gcttctttca attgctcact
    21241 cgttttccaa tcttttgttc caatcaacga ccacgcaacg gttttgacga aaaacttcat
    21301 aaatcgatca tccgaatgct gctgtgctgt tagcttcaaa tcaacaggtc cgcaataaga
    21361 aatggttcct ttcagactat cttttggaag tagctgtttg attttcattt gtttagcata
    21421 cgcatcattc gtttgtatag ctgcatattg caatgcgatt tgtgaacctg cactatctcc
    21481 accaaaaaat aattgttcca tgtctagcaa tttgtcgtct ttttcttcag ctaataaatc
    21541 tttgatcagt tcattcactt gaagaacttg attagggtat tctgaatcag gcgctaattc
    21601 ataattcatc gcaaccactg cgatgttggc gtctgaaact aattttgtcg caaattcttt
    21661 gacacccgat ttatctccgc cgacgaatcc tccaccatgt acccaaaata gaacaggaac
    21721 aggccccttg ctgttttttg gatagtagat gtcataagta ttctctttat acttggactc
    21781 atacgtcaaa tctgtttttt tcgccacgtt tttttctgct tgatcgaacg tttttttatc
    21841 agtgatttga acagtatttg aaaacatatg gttgatcaag aatgctccag gtctggggga
    21901 aagctggaag gcaagaaaga ttgcaaacgc gatcccaaga atgattccga agaaccatcc
    21961 gataaattta agaattttct ttttcataag gctccctcag tagttagtat taagcattct
    22021 gattatacca tagtgttatt tcctatcaag ctctcctaga tgatttaatg attttcccca
    22081 aacttcttct gcaatgcttt tgacaaaaga aattttttcc attgttcttc aaacaaaaca
    22141 ttttcttctt ctgttgaagc aaatccacat tgaggactta agcacaaacg atccaaaggc
    22201 agatatcgtg tcgcttcgta gatccggtca atcacttgct ggtgctcttc catttcgcca
    22261 tttttcgtta cagtcaaaat ctaagacaac taatttatct tcagagactt tctctaaaag
    22321 aacaaaactc ccagcacgtt cactatcgta ttctaaataa taggcacgga cattttcttg
    22381 agtaaaataa tgggtctgct acgtcgtcat cccccctgat gccgccaaaa tcgaataata
    22441 atttccgcgt caaacatgta tatttagtgt tgaatcattt gagaatatga aaataaaaat
    22501 ctttttgatc aatcagttaa tcaaattgaa ataacgaaaa atctgagaca gaatgacgtt
    22561 cattctgacc cagatttgat tttgcacaac tcaacagtcc ttattggcaa atcgccaaaa
    22621 taatgtagac taac
//
LOCUS       DADGHT010000043        22419 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.043, whole genome shotgun sequence.
ACCESSION   DADGHT010000043 DADGHT010000000
VERSION     DADGHT010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.043"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..583
                     /locus_tag="JX887_001486"
     CDS             <1..583
                     /locus_tag="JX887_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257481.1"
                     /translation="VEKNGVYKGDFHFQNAETIEREHHYFDLLVNTVVELAKWAKSNE
                     TYSQVLKRIMSQETSFIYELSKSNLKYTYNEDELEILDNPENSQWIKELKREDFIETL
                     RILKSLFDLKLAKATIMGIERDSYYWEEIGLYAPQIEGEDKEKRIDNIINYINSLSEP
                     LKCRGLDFIGTLGWTETYYEKIYKEIIEQYFPK"
     gene            766..3441
                     /locus_tag="JX887_001487"
     CDS             766..3441
                     /locus_tag="JX887_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HAX1257482.1"
                     /translation="MKMNHTSIQKHLQLLNTLGISYVNLRTFSTLNKKTVSHIFSTAD
                     SQAIINYLEKQKLSEGTVNITYNPIKQEVITQKKHSVRDNDIEKIRFVFIDIDPKRKE
                     GSATDSEKKKAENVMEQVERYLKEKRIESFVKVDSGNGYHIFLPINEQPNNHETILTI
                     QNFLQLLHRRFGVEDEVDIDTSVYNPSRLCKLVGTPAVKGKSTKERPHRLSSFLSIPD
                     NIDRSNCFKILEQIVEENSMMSTSRVKSHPSFREVLPFIQADYKQWLAHYPELTYTIK
                     EGDHKGVTLLIFDECPLRKHTNNSNGSCLSVTADNKIRFHCLHASDKNKDIQDFVKKY
                     PLPKPVNPSVESLESNQEYYFDQFKLNQEGVFLVKEGQEEKVACPMFIKQIRKNIEQK
                     VITLVLAYYVDHCWDEIEIEGGCLQTNNFKQLAKHGLIIKARREAEVVDFLQIQRENA
                     PIFFEHESLGWKKENEAMIFQLQDSFGREIPSVLTKNSCYQLTTNGTEAEFDALVHKY
                     VLGTNLELAWSIGIASIVLGYLNVTKANTFLSLLINLQGKSTTGKTTTLHFIASLFGN
                     PTTVLRNMNATNKAIIKLASNNQGGVPLILDELGAATQNNFSSLIYQLASGEERLRLD
                     SNCQLMPQETFSVLTLTSSEERLENYFNEKLTGLKVRYIEFSDIKFTKDANHAEKVKS
                     LSSNTFGWGIKLFLLKLFEQGIAKIEATFVEAQKKIWAVLPEHSLKQRIGNNLALIYS
                     GALLIQDILGYPLRLEHIQTVLINSYEQLIVDTSLGSEQTVFDRVKTLLVMNSHKFLT
                     NSDNKHTPSTIWGKVSIQKNGDIKVNIFPIPFEDLLRREFQVKDLTYLFRQLLDSGNM
                     CAEKGRRTKRIHMNRQVLPTYEILLPSSLKSYFRL"
     gene            3623..3862
                     /locus_tag="JX887_001488"
     CDS             3623..3862
                     /locus_tag="JX887_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257483.1"
                     /translation="MTKNKMTLKAEVLLYIQEHFSNQAFFTKPIYLAFEIRGVSAGSI
                     GGTLQALKNEGYLENHFVQRSFNGRVAKEWYLVHS"
     gene            3878..5251
                     /locus_tag="JX887_001489"
     CDS             3878..5251
                     /locus_tag="JX887_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1257484.1"
                     /translation="MRVACYDRTSVYEEAKISNDAQYDAVKEYVLEKYEQIPQRFSDK
                     GESGGKADRPAFRQLRAWVCASEEEGVIYVWRYDRLARQAKIALEFIELCQQHQVQVY
                     SISEPLPASFSHASTNKLFVQLLFTFAEQQRNVIIENVRAGLAYKKQQRQYLSSAVPY
                     GYRLVNGKIQQEAHEAKVVRHIFQLYLTKKYGYKKLCQRLTQQKFFFRERPFQPYHIY
                     SILKNPLYYGEIKGGSLGKYLGTFEPILSKTIFLQAQEIRQSRCTAKKDTYPYLLRQK
                     IRCPFCGRHLSSKYQWNTKKTKTLHYYHCTDRSCQGIFLRAERVESEVLEKIQAFFQY
                     EGVYQALIAQLTQQLAEKRKDEKHKVIQQKKQEAQWLKAFEEGNCSLEELKQQLQALQ
                     KPRSTSSFLSLQQCEAKVKEWLQLKDLSSRQLLCDHVCRIEVTKEKTVCGIYFRQMTQ
                     NILEGNE"
     gene            5255..6892
                     /locus_tag="JX887_001490"
     CDS             5255..6892
                     /locus_tag="JX887_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1257485.1"
                     /translation="METTPTKRVALYIRVSTQEQALEGHSIQAQEQNGRQFAERMSYE
                     VVEVYADEGISGKSTKNRFAYQRMMNDARNHRFDLLVIWKLTRLGRNMLDVLQTVEEL
                     LRYDVGLHSISEQFDVTTSTGKLMLQLLGSFGEFERNQIAENVQMSMQSLVKDKKRYA
                     GGRRLGYVSGIDTNGQKQLVIEPEEAKIVRLIYAKYLGGAGYRAIANFLNRQGYQTVK
                     KNAFSTTAVKDILRNKIYAGYLEYARYINWETKRRKGKNPKPILVKGTHEPIISEEDY
                     QKVQERLVLEGKQPKWNHTGENVLTGLLRCPECGAPMAASNVTNTLKDGTKKRIRYYS
                     CSVFRNKGASVCHANSIRAEQAETFVADRLKEIVQLPEVLPRLVAALNEEIVRQSQPL
                     EQELVVLLERKEELKTKIEKWEAALEDSPELFPMLKDRLDELTEKRRQLHIRENEILG
                     IFQQQGEPIQVKDVQRILTSLDRFLAQSEKKQVKALYRTFIEKITFDPNYKEILEITM
                     KFTPAVVQQLNEQYQIAVSKTKDTAIFVLKTPFTLTI"
     gene            7055..7987
                     /locus_tag="JX887_001491"
     CDS             7055..7987
                     /locus_tag="JX887_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257486.1"
                     /translation="MKKMGKCILCEKYTELTKEHVPPKKSGNTGGKKTRTGNLDDFLK
                     SDFTKGDFPKGIKRKPQGNVYYTLCSKCNSFFGSEYVEEYIRFAEDNKNFLYNNTSLK
                     NGKSDLTHSIKKMNSLRVAKAIVAMFFSLNGDEDSMDKPFLDSVREYLSNPKSTLFPH
                     EDYKIIMNYYLPIGAPQNSKIKIPNDIVNDGDTHNVIKGFMPLDLSTGRKIRFSEIQY
                     EGIGFTLIDLKNSTFEIKEGLDLKNLLCADDKIKKIQLYKVPILTPTVLTMLEMENNI
                     NYIDSGSDLLIRWQVITNFLMELKKYSNTQTKFS"
     gene            8112..8369
                     /locus_tag="JX887_001492"
     CDS             8112..8369
                     /locus_tag="JX887_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HAX1257487.1"
                     /translation="MEDSPELFPMLKDRLNELTEKRRQLQIRENEILGIFQQQGEPIQ
                     VKDVQQILTSLDCFLIQSEKKQVKALYHTFIEKITFDPNQK"
     gene            8601..9005
                     /locus_tag="JX887_001493"
     CDS             8601..9005
                     /locus_tag="JX887_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HAX1257488.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFLASHIYGKILSAKFE"
     gene            9024..11681
                     /locus_tag="JX887_001494"
     CDS             9024..11681
                     /locus_tag="JX887_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1257489.1"
                     /translation="MEELKERIVNYVIENSEIKNKWGNNTAQKISEKLNVSRNIVSQY
                     LNEFVKDGEFGKINTRPVIFFSLPEKVPNQQIFSSSEEAEKWYDSSFRVGIERVIGSQ
                     GSLRNVIAQIKAAIYYPPNGLPILLHGETGTGKSYLANYVYKDLLANNYIEEKASFIS
                     VNCSEYANNPELFLSNFFGHVKGAYTGAEDGRKGLAELANNGVLFLDEIHALSNECQE
                     KLFQFMDTRKFHRMGDNENWYTSSCWIIFATSEPPEDKLLSTLLRRIPVKLTLPTLDS
                     RSLYERKQLIKIFFKSEEERLAKKILISQQLLDFLLNYRFSENVGNLKNIIQLTCANA
                     FYFLDDLEELYIQMYHLPQWVNFNGMKVMKRQNELKYIQMDDLEKVDEVFNINELIEY
                     LYQTWKKDTDKQQLFEKYDRYFRQKNVDIQNNSALTYPTYQEIRFRQYVKEIERDFQI
                     EFDYYYLQITSIFLNSWIYQIQLTSDDKLYSFINDINSWCSREVQLVNRFIQIGDIYL
                     TKIQKNVLVILFKLMCSKEFQQKRLALILAHGDLTATCIASTANRIVERYIYDAIDMP
                     LMTSSSEIADKINRYLQECTGYEEIILLVDMGSLEKIYLNLELDAQKKFGLLNNVSTR
                     MAIDVANQILLDLPLKQILEQVKENQNVDYIYESSNIKKDMIVCSCASGLGTSFKLKK
                     ILEDSFPRDTDLVIETCDYYSLVNENYLSELRKENNILFIVGTLNPHLEDVEFFSIED
                     MILGMNISKFSNQLNRHFNDNELKVLNNNILKNFSLTNLMEQLTILNPTKLLERVSDA
                     IYILQNDLGISFDNNTCFGLYVHISCLIERLVKQNTLEDEIYFNETSEEFQKFQTHFK
                     QSFSVVEHYYSVDIPIHEVKYVYDYVKRA"
     gene            11753..12229
                     /locus_tag="JX887_001495"
     CDS             11753..12229
                     /locus_tag="JX887_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1257490.1"
                     /translation="MSIVMSRVDNRLLHGIIVTQWAPMSKANRVMVIDDSVANNDIQK
                     SSMRLARPAGMAVSIITEETAIANFKKGKYDQEKVFVIVKEPETILHLVDNGIRIDRL
                     IVGGTVVKDNALQLSSRAYASDENISTYKKLLDSGVEIVTQFVPADKAQEIQSKLG"
     gene            12243..13031
                     /locus_tag="JX887_001496"
     CDS             12243..13031
                     /locus_tag="JX887_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1257491.1"
                     /translation="MHFTIFQIIMLTILAFIKHVDYYGIPMIFVNYAVFWGLFTGILM
                     GDIKTGLIVGGTVQLMSLGVAGFGGSSVPDYGTCAIIATAFGSQLGVEAGLAIGLPVG
                     MLGVQLDVIVKILNGFVVRKSQEYANKREFKKMNSVLWLGPIFFGLSAAIPVFIAVTL
                     GQSAVNYVLDVLPNWFMDGLTLAGKMLPAVGIAMLLRFMPTGRYISYLLVGFFLAAFL
                     KVPIIGAAIIGFALAFNVYHRAEKDAQITASAGASDVGFIGEDE"
     gene            13033..13830
                     /locus_tag="JX887_001497"
     CDS             13033..13830
                     /locus_tag="JX887_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010238514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAX1257492.1"
                     /translation="MSEKYQVTKKDLRKANYRWLMSVCTFNYQTQQGASVTYALSPIL
                     RKLYKDDDEYIEALNNHFQYYNTQPWLAAIILGACVAMEEKQGLEAKDAINDFKVGTM
                     GPIAGIGDSLLMTMIPTIMGSIAAYMALENNPVGIFLWFILIMVIFFFRMRGFEFGYK
                     QGMKIVTEYGEKINYLTEAASVLGLTVVGSLIASVISVSTPLKFTFGEVSMKIQPMLD
                     KILPTLIPVIITAAAYYLLSKKKISMTILILLVIVFAMVMAAFGILA"
     gene            13849..14244
                     /locus_tag="JX887_001498"
     CDS             13849..14244
                     /locus_tag="JX887_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAX1257493.1"
                     /translation="MRRLIIASHSILAEGFKETLEFLTGMHNQISSLCAYVEEIDDID
                     EQIKELVDTTDEIIVLTDMAGGSVNQKFFTYISDRVHVIAGMNLPLAMSIALQLGNDN
                     LDIGAIIAEAQQQIIYMNNQKSEERIEDE"
     gene            14246..15367
                     /locus_tag="JX887_001499"
     CDS             14246..15367
                     /locus_tag="JX887_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAX1257494.1"
                     /translation="MNCLNNIWLHKGEESRTISPENKNGEKGKAAMTASHLGIGRKGS
                     PSVPINAGETITLAEMEGPGILRHFWMTVTDKTIAGSFVLRDLILRIYWDDESTPSVE
                     SPLGDFFCNGFGTRCEVNSLPIVVNPTSGMNCYFEMPFRKKAKITLTNEHPEFIKHIF
                     YTFNYALTEVPDDAMYFHAKWNREPITTKGKDYTLIDGIKGTGYYVGTYFALCALERY
                     WWGEGEFKFYIDGDEDFPTITSTGAEDYFGGAWAFHKKNFGERAYAQNFNTLFMGYPF
                     QSKRDHTRDYFSAGKPNPNPVHGFGDDALPMHGLYRWHLPDPISFKENLRVTFQTLGN
                     DDIKLYERQDDISSVAYWYQKEPHEFFEKLLDREERIPR"
     gene            15387..16256
                     /locus_tag="JX887_001500"
     CDS             15387..16256
                     /locus_tag="JX887_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1257495.1"
                     /translation="MYGSIEAGGTKFVCAIGNDDLKVLERVSFPTTTPNETMSLVIDF
                     FNHYKEQLESIGVGSFGPIDIHRESKTYGHITSTPKTAWKNFDFVGTLNKHFEIPIAW
                     TTDVNAACYGEYVSGHGKGLSSVVYYTVGTGIGGGAIQDGIFVEGFSHPEMGHTLVKR
                     HSGDTFSGTCPFHHDCLEGLASGPAIEMRTGTKGQDLSIEDPFWEIEADYIAQCACNT
                     TLMLSPDIIIFGGGVMQQEHLKKKVQRRFLELINGYVDTPNIEEYIVTPKLADNAGTI
                     GCLTLAKDVRINS"
     gene            16457..16966
                     /locus_tag="JX887_001501"
     CDS             16457..16966
                     /locus_tag="JX887_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HAX1257496.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            17066..17716
                     /locus_tag="JX887_001502"
     CDS             17066..17716
                     /locus_tag="JX887_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257497.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            18167..19105
                     /locus_tag="JX887_001503"
     CDS             18167..19105
                     /locus_tag="JX887_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAX1257498.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            19118..20170
                     /locus_tag="JX887_001504"
     CDS             19118..20170
                     /locus_tag="JX887_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1257499.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            20436..21071
                     /locus_tag="JX887_001505"
     CDS             20436..21071
                     /locus_tag="JX887_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAX1257500.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            21262..22053
                     /gene="msrA"
                     /locus_tag="JX887_001506"
     CDS             21262..22053
                     /gene="msrA"
                     /locus_tag="JX887_001506"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAX1257501.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
BASE COUNT         7667 a         3300 c         4556 g         6896 t
ORIGIN      
        1 agtggaaaag aatggagttt ataaaggtga ttttcatttt caaaatgctg agactattga
       61 acgagaacat cattatttcg atttattagt gaatacagtg gtagaattag cgaaatgggc
      121 aaagtcaaac gaaacttata gtcaagtact taaaagaatt atgagtcaag aaacttcatt
      181 tatctatgag ttaagcaagt caaatttgaa atatacttat aatgaagatg aacttgaaat
      241 tttagataat ccagaaaatt cacaatggat taaagagttg aagagagaag actttattga
      301 gacactaaga attctaaaat cgttatttga tttgaaatta gccaaagcta ccatcatggg
      361 aattgaaaga gattcatatt attgggagga aattggacta tatgctcccc agattgaagg
      421 tgaagataaa gagaaaagga tagacaacat tattaactat attaatagtt taagtgaacc
      481 tttaaaatgt agaggacttg attttatagg aacattagga tggacagaaa catactatga
      541 gaaaatatat aaagaaataa ttgaacaata ttttcctaaa taatttaata aggattgatt
      601 tattgtaaaa gaaaaaagtt gtgattttgg aaatcacaac ttttttcttt tgtcaagatt
      661 ttgagtggga tatatttttg tagaactgaa gatcatgaaa ttatgagagg ttggaggtaa
      721 tgtagtcata caaataaaaa ttttttagaa agtgagtggt aattaatgaa aatgaatcac
      781 acttcaattc agaagcattt acaactgtta aatacactgg ggatttctta tgttaatttg
      841 agaacttttt ctacattaaa caagaaaacc gtttctcata ttttttctac tgcagattct
      901 caagcaatta ttaactattt agaaaaacag aaattgtctg aaggtacagt aaacataact
      961 tataatccta ttaaacaaga ggtgattaca caaaaaaagc attctgtgag agacaatgat
     1021 attgaaaaaa ttcggtttgt atttattgat attgacccta aaaggaaaga gggaagtgca
     1081 acagatagcg aaaagaaaaa ggcagaaaat gttatggaac aagtagaacg ttatttgaaa
     1141 gaaaagagaa tagaatcatt tgtaaaagtt gatagtggga atggctacca tatttttctt
     1201 cccataaatg aacaaccaaa taatcacgag acgattctta ctattcagaa ttttcttcaa
     1261 ttacttcacc gaagatttgg agtagaagat gaagttgata ttgatacttc tgtttataat
     1321 ccttcaagat tatgcaaatt agttggtaca ccagcggtca aaggaaagtc cacaaaagag
     1381 cgtccgcatc gtttatctag tttcctttct attcccgata acatagatag aagtaattgt
     1441 tttaaaattc ttgaacagat agttgaagaa aattccatga tgtcaacctc tagagtaaaa
     1501 agccatccat cttttagaga agtgttacct tttattcaag cagactataa acaatggtta
     1561 gctcactatc ctgaattaac ttataccata aaagagggcg atcataaagg agttacctta
     1621 cttatatttg acgaatgtcc attaagaaaa cacacgaata attctaatgg ttcttgtttg
     1681 tctgttacgg ctgataataa gattcgattt cattgtctgc atgcttcgga taaaaataaa
     1741 gatattcaag actttgtaaa aaaatatccg ttgccaaaac ctgtaaatcc ttctgtagaa
     1801 tcattagaat ccaatcaaga atattatttt gaccagttta aactgaatca agaaggagta
     1861 tttttggtga aagaaggtca agaagaaaaa gttgcttgtc cgatgtttat taagcaaata
     1921 cgcaaaaata tcgaacaaaa agtcattaca cttgttcttg cctattatgt cgatcattgt
     1981 tgggatgaaa tagaaataga aggtggatgt ttacaaacta ataattttaa acaattagca
     2041 aaacatggct taatcattaa agctagaaga gaagctgaag tcgttgactt tttacagatt
     2101 caacgggaga atgctccaat cttttttgaa catgaatctc ttggctggaa aaaagaaaat
     2161 gaagcaatga tttttcagtt acaagattct tttggacgtg aaattccttc tgtattaact
     2221 aaaaactcat gctaccaatt aacaactaat ggtacagaag cggaatttga cgcattggtt
     2281 cataagtatg ttttaggaac gaacttagaa cttgcttggt cgattggtat tgcttctatt
     2341 gtgttaggct atttaaacgt tacgaaggct aatacttttt tgagtttact aattaaccta
     2401 cagggcaaga gcacaacggg taaaaccact acgttacact ttattgcctc tttatttgga
     2461 aatccaacta cggttcttag aaatatgaat gctaccaata aagccattat aaagctagca
     2521 tcaaacaatc agggaggtgt tccactaata ctagatgagt taggagcagc aactcaaaat
     2581 aactttagct cgttgatcta tcaattagct tcaggagaag aaaggctaag attagattct
     2641 aattgtcagc ttatgccaca agagactttt tctgttttga cccttacctc ttctgaagag
     2701 cgtttggaaa attatttcaa tgagaaatta actggtttga aagttcgata tatcgaattt
     2761 tctgatatca agtttacaaa ggatgcgaat cacgcagaga aagttaaaag tctttcttct
     2821 aatacttttg gttggggtat aaagttattt cttttgaaac tctttgaaca agggattgca
     2881 aaaattgaag caacttttgt cgaagctcaa aaaaaaatat gggctgtttt acctgaacat
     2941 tctttgaagc aacgcattgg taataatcta gctttgattt atagtggagc tctcctaatt
     3001 caagatatac tgggctatcc tttacgatta gagcatatac agacggtgct tattaattcg
     3061 tacgaacagt taattgtaga tactagttta ggaagtgagc aaacggtatt tgaccgagtg
     3121 aaaacgttgt tggtgatgaa tagccataaa tttttaacaa acagtgacaa caaacatacg
     3181 cccagtacga tttggggaaa agtatcaatt caaaaaaatg gggatattaa ggtaaatatt
     3241 tttcctatcc cgtttgagga cttgttaagg cgagaatttc aagtaaagga tctaacctat
     3301 ctttttagac aattgcttga ttcgggtaat atgtgtgcag aaaaagggag aagaacgaaa
     3361 cgtattcaca tgaatcgtca agttcttcca acatacgaga ttctattacc ttcttcactc
     3421 aaatcgtatt ttcgattgta atttagaata aaccaaagta tgaaagtgag gcaccatgtt
     3481 atggaaatat ttcttattga tttagcaaaa caactgatta cttatctgta tgatgacgag
     3541 caaacccaaa cggaagtaaa tgaagcttga tctatgcttc atttacttca ttcaatcaaa
     3601 catttaagaa aggggaattc taatgactaa aaataaaatg acactaaaag cagaggttct
     3661 tctgtatatt caagaacatt tttctaatca agcctttttt acaaaaccaa tttacttggc
     3721 tttcgaaata agaggggtat ctgctggatc tattggaggt actcttcaag cgttgaagaa
     3781 cgaaggatat ttagaaaatc actttgtgca acgttcgttc aatggaagag tcgcgaaaga
     3841 atggtattta gttcattcat agagaggtga ttcaagcatg cgtgtggctt gttatgatcg
     3901 aacgtctgtt tatgaagaag cgaaaatcag taatgacgct caatatgatg cagtgaaaga
     3961 gtatgtttta gagaaatatg aacaaattcc tcaacgattt tcagacaaag gagaatcagg
     4021 tggaaaagcg gatcgtccag cttttcgaca gcttagagct tgggtttgtg cgtcagaaga
     4081 agagggggtg atctatgtct ggcgttatga tcgattggca cgtcaagcca aaatagcctt
     4141 agaatttatt gagttgtgcc aacaacatca ggttcaagtt tattcgattt ctgaacctct
     4201 tcctgcttct ttctcgcacg cgtcaacgaa taaactattt gtgcaattat tgttcacttt
     4261 tgcagaacaa caacgaaacg tcattattga aaatgttcgt gccggacttg cctataaaaa
     4321 gcaacaacgg caatatttgt cttctgcggt tccatatggg tatcgtttag tgaatgggaa
     4381 aatccaacaa gaagcacatg aagcaaaagt tgtccgccat atctttcaac tttatttgac
     4441 taaaaaatat ggctacaaaa agctttgtca acgattgacg caacaaaagt tcttcttccg
     4501 tgaacgtcct tttcagccct atcatattta tagtatccta aaaaatccat tgtactatgg
     4561 cgaaatcaaa ggaggatctt tggggaagta tctaggaacc tttgaaccga ttctctcgaa
     4621 aacaatcttt ttacaagccc aagagattcg ccaatcaagg tgtacagcta aaaaagatac
     4681 gtatccgtac ttattacgtc aaaaaattcg gtgtcccttc tgtggtcgtc atctgagttc
     4741 gaagtatcaa tggaatacaa agaagacgaa gacgcttcat tattatcatt gtaccgaccg
     4801 aagctgccaa ggaatctttc ttcgggcaga aagggttgag tcagaagtat tggaaaagat
     4861 acaggctttt tttcaatacg aaggcgtcta tcaagccttg attgcccaat tgacgcaaca
     4921 attagccgaa aagcgaaaag atgaaaaaca caaagtaatc caacaaaaga aacaagaagc
     4981 acaatggctc aaggcatttg aagagggcaa ttgttcactg gaagaactca agcaacagct
     5041 gcaagctctt caaaagccga ggtctacttc ttcgtttctt tcactccaac agtgtgaagc
     5101 aaaagtgaaa gaatggcttc aactaaaaga cctctctagt cgacaattgt tatgtgacca
     5161 tgtttgtcgg atcgaggtaa caaaggaaaa aacagtctgt gggatttact tccgacaaat
     5221 gacacaaaat attttagaag ggaacgaatg atctatggaa acgacaccaa ccaaacgagt
     5281 cgcattgtat attcgggtga gtacccaaga acaagcttta gaaggacata gtattcaagc
     5341 acaagaacaa aatggacgac agtttgccga acggatgagc tatgaagtgg tagaagttta
     5401 tgccgatgaa gggattagtg ggaaatccac aaaaaatcgg ttcgcctatc aacgaatgat
     5461 gaacgatgct cggaaccatc gttttgatct actagtgatt tggaaattga cccgtctcgg
     5521 acgcaatatg ttagatgtct tacaaaccgt cgaggaactg ttgcgatatg atgtggggtt
     5581 acattcgatc tcggaacaat ttgacgtgac tacttcgaca ggaaaactaa tgttacaact
     5641 ccttgggagt ttcggtgaat ttgaacgcaa ccaaattgcg gagaatgttc agatgtcaat
     5701 gcaaagctta gtgaaagata aaaagcgtta tgcaggtgga cgacgtttag gctatgtcag
     5761 tggtattgac acgaatggtc aaaaacaatt ggtcattgaa ccagaagagg cgaaaattgt
     5821 tcgtctgatc tatgcaaaat atttaggcgg agcagggtat cgagcgattg ccaatttttt
     5881 gaatcgtcaa ggatatcaaa cagtcaaaaa gaatgctttt tctaccacgg cagtcaaaga
     5941 tatcttacgc aataaaattt atgcagggta tttagaatat gcacgctata tcaattggga
     6001 aaccaaacga cgaaagggca agaacccaaa accgatttta gtgaaaggta cccatgaacc
     6061 gattatttcg gaagaagatt atcaaaaagt gcaagaacgc cttgttttag aaggcaaaca
     6121 gcccaaatgg aaccatacag gtgaaaatgt attgacaggc ttgttacgtt gtccagaatg
     6181 tggggcaccg atggcagcga gtaatgtcac aaatactcta aaggatggca caaagaaacg
     6241 aattcggtat tattcttgtt cagtctttcg gaataaagga gcaagtgtgt gtcatgccaa
     6301 ttcgattcgt gccgaacaag cggaaacatt tgtcgccgac cgattaaagg agatcgttca
     6361 gctaccagaa gttcttcccc gattggtggc agcgttaaat gaagaaatag tgcgacaaag
     6421 ccaaccattg gaacaagaac tcgtggtgtt actggaacga aaggaagaat tgaagactaa
     6481 aattgaaaaa tgggaagctg ctttggaaga tagtcctgaa ttgtttccga tgttaaaaga
     6541 ccgcttagac gaattgactg aaaaacgacg acagttgcac attcgagaaa atgaaatctt
     6601 agggatcttt caacaacaag gagagccgat tcaagtcaaa gatgtccaac ggatattgac
     6661 tagtttggat cgttttcttg cccagagtga gaagaagcaa gtcaaagcct tgtatcgtac
     6721 ctttattgag aaaataacct ttgatcctaa ctataaggag atattggaga ttacaatgaa
     6781 attcacgcct gccgtggtac aacaattgaa tgagcaatat caaatagccg tatccaaaac
     6841 aaaggatacg gctatttttg tgttaaagac accctttacg ttaacgatct agtctaggtt
     6901 atatcaaaca acgttagagg ggcgctaacg cttctctagc gatttgaaat cgttagatga
     6961 gtcgttaggg aggtccttat cataaatagg gatatttatt aatgaatatt tgaaatataa
     7021 ttgtatataa gaattaaaaa gagtggggat agatatgaaa aagatgggta agtgtatttt
     7081 atgtgaaaaa tacactgaac ttactaaaga acatgtacca cctaaaaaat cagggaatac
     7141 tggaggtaaa aagaccagaa ctggtaattt agatgatttc cttaagagcg attttacaaa
     7201 aggtgatttt ccgaagggga ttaaaaggaa acctcaagga aatgtttatt atacgttatg
     7261 tagtaaatgt aatagttttt ttggtagtga gtatgttgag gaatatatta gatttgcaga
     7321 agacaataaa aatttccttt ataacaatac aagtttaaag aatggtaagt ctgatttaac
     7381 acattcaata aagaaaatga attcacttag agttgcaaaa gcaattgtag caatgttttt
     7441 tagtttaaat ggggatgaag attcaatgga taagccattc ttagattcgg tacgagaata
     7501 tcttagcaat cctaaaagta ctttatttcc tcatgaagac tacaaaatta taatgaatta
     7561 ttatcttcca ataggtgctc cacagaattc taaaatcaaa attcctaatg acattgtaaa
     7621 tgatggtgac actcacaatg taataaaagg ttttatgccc cttgatctat caactgggag
     7681 aaaaattcga ttttcagaaa ttcagtatga aggaattggt tttactctta tagatttaaa
     7741 aaattcaact tttgaaataa aagaaggatt agatttaaaa aatctccttt gtgcagatga
     7801 taaaatcaaa aaaatacaat tgtacaaagt ccctatatta acaccaacag tacttacaat
     7861 gttggagatg gaaaataata ttaattatat tgactcaggt tcagatttgc tgattaggtg
     7921 gcaggtaata actaattttc ttatggaatt aaaaaaatac agtaatactc aaacgaagtt
     7981 ctcttgaagt tataaagaat acaataaata taaatttcct ttagactata ttaaaatcag
     8041 caatcgaagg aaaataaacg aagaaaatgg tacgcaaaat ctaactatta gagcaaaaac
     8101 aggaagctgc tttggaagat agtcccgaat tgtttccgat gttaaaagat cgtttaaatg
     8161 aattgactga aaaacgaaga cagttacaaa ttcgagagaa tgaaatctta gggatctttc
     8221 aacaacaagg ggaaccgatt caagtcaaag atgtccaaca gatattgact agtttggatt
     8281 gctttcttat ccagagtgag aagaagcaag ttaaagcttt gtatcacacc tttattgaga
     8341 aaatcacctt tgatcctaat cagaagtaga tattgccgat cccgatgaga ttcacaccta
     8401 ctgtgatttg ataattgaat gagtaatatc aaatagccgt atccaaacca aaggatatgg
     8461 ctatttttgt gttagggata tacgtcacgt agcttgttat caagaataag tttctttatt
     8521 tttttgcttt ttctaaaact gagtatgcta aaataagagg gtatatagca actttaaata
     8581 agagatagga gtgtatcttt ttgggtgcag aattaaatca gaagttattt agtgcggcag
     8641 ataatctccg tagtaaaatg gatgcgtcag aatataaaaa ttatttattg gggctgattt
     8701 tctataaata tttatccgac cgtttgttgg aacaagtggt tcttttagca gatgaatcct
     8761 tagaggaata tgacacagta agcaaacaaa cgatgttgta tcgtgaatta ctttcagatg
     8821 aagaatcaaa agaagatctg attgcaacaa tcgttgatat tttggggtat gcgatttcgc
     8881 cagagtatct tttcaacgtc ttagcggatc aagcaaaaca agcaacgttc caattgaatg
     8941 atctaaacaa agccttttta gcaagtcata tttatggaaa aatactgtcg gcaaaattcg
     9001 aatagtgtcg aggaggtgct gtgatggaag aattaaaaga acgcattgtc aattatgtca
     9061 tagagaactc tgagattaaa aataaatggg ggaacaatac agcacagaaa atatctgaaa
     9121 aattaaatgt tagtcgtaat attgtctctc aatatttgaa tgaattcgta aaagatggag
     9181 aatttggaaa aatcaatact cgtccagtaa tcttcttttc tttaccggag aaagttccaa
     9241 atcaacaaat ttttagctct tcagaggaag cggaaaaatg gtatgatagc tcttttaggg
     9301 ttggaataga aagggttatc ggaagtcaag gaagtctgcg aaatgtaatt gctcaaatta
     9361 aagcagcaat ctactatccg ccaaatggct tacccatttt acttcatggc gagactggaa
     9421 ctggaaaaag ctatttagca aattatgtgt ataaggattt gttggccaat aattatatag
     9481 aagagaaggc atctttcatt tcagttaatt gtagtgaata tgccaataat ccagaacttt
     9541 tcttgtccaa tttttttggg catgtaaaag gtgcatatac aggagccgaa gatggaagaa
     9601 agggtttagc agaattagct aataatggag tcttattttt agatgaaatt catgcattga
     9661 gcaatgaatg tcaggagaaa ctttttcagt ttatggatac gaggaaattt catcggatgg
     9721 gtgataatga aaactggtac acatcaagtt gctggattat atttgcaaca tcagaaccac
     9781 ctgaggataa actattatca actttgttga gaagaatacc tgtaaagcta acacttccaa
     9841 cattagacag tcgttctctt tatgaaagaa aacagttaat caagatattt tttaaatcag
     9901 aagaagaaag actagcaaag aaaatactga tatctcaaca attattagat tttttattaa
     9961 actatcgctt tagtgaaaat gttggcaatt tgaaaaatat cattcaattg acctgtgcca
    10021 atgcctttta tttcttagat gatttggaag aactttatat tcagatgtat catttaccac
    10081 aatgggtgaa tttcaacggc atgaaggtta tgaaaagaca gaatgaatta aaatatattc
    10141 aaatggatga tttggaaaaa gtagacgaag tttttaatat caacgaactt atagagtatc
    10201 tttatcaaac gtggaagaaa gacactgata agcagcagct ttttgagaaa tatgatagat
    10261 attttagaca aaagaatgtt gatatccaaa ataattcagc tttaacatat cccacctatc
    10321 aagagattcg atttagacag tatgttaagg aaatagagag agattttcaa atagaatttg
    10381 actattatta tcttcaaata acgtctatct ttttgaattc ttggatttat caaatccaat
    10441 taacatcgga cgataaatta tattccttca tcaatgatat taatagttgg tgtagtcgag
    10501 aagttcaatt agtcaatcgt tttattcaaa taggggatat ttatttaaca aaaattcaaa
    10561 aaaatgtttt ggttatttta tttaagttaa tgtgtagtaa agaatttcag caaaaacgtt
    10621 tagcactgat tttggctcat ggagatctaa cggcaacctg tatagcaagt actgctaata
    10681 ggatcgttga gagatatata tacgacgcca ttgatatgcc actaatgact tcaagtagtg
    10741 agattgcaga caaaattaat agatacttac aagagtgtac cggatatgaa gaaattattt
    10801 tacttgttga tatgggttca ctggagaaaa tttatctaaa tttggaacta gacgctcaaa
    10861 aaaaattcgg actactaaac aatgtttcaa caagaatggc tattgatgtt gcaaatcaga
    10921 tattattaga tttaccgctt aaacagattc ttgaacaagt aaaagaaaat caaaatgtgg
    10981 attatattta tgaatcatca aatattaaga aggatatgat tgtctgttct tgtgcaagcg
    11041 gattaggaac ttcgtttaaa ttaaaaaaga tacttgaaga tagctttcca agggatactg
    11101 atcttgtcat agaaacgtgt gactattact ctttagtgaa tgaaaactat ttatcggagc
    11161 ttcgtaaaga gaacaatatt ctttttattg ttggaacact aaatccacat ctagaagatg
    11221 tagaattctt ttcaattgaa gatatgattt taggaatgaa tataagtaaa ttctccaatc
    11281 aattgaatag acactttaat gataatgaac tgaaagtttt gaacaataat attctgaaga
    11341 attttagtct aacgaattta atggagcaat tgaccatatt aaatccgact aaattattag
    11401 aacgggtttc agatgctata tacatcttac aaaatgatct aggaatttca tttgataata
    11461 atacgtgttt cggattatat gttcacatta gttgcttaat tgaacgatta gtaaaacaaa
    11521 atactttgga agatgaaatt tatttcaatg aaacgagtga ggaatttcaa aaatttcaga
    11581 cacattttaa gcaatctttc agtgtcgttg aacattatta tagtgtcgac atcccgattc
    11641 atgaggttaa atacgtttat gattatgtaa aaagagcttg atttatcaag ttctttttgt
    11701 tttggcatgg taattgcttg taagaaaatg aaagataaag gaggaagtat ttatgagtat
    11761 tgttatgtcg agagttgata accgtttatt gcatgggatt attgtcacgc aatgggcacc
    11821 aatgtctaaa gcaaacagag tgatggtgat cgatgattct gtcgcaaata acgacatcca
    11881 aaaatcaagt atgcgtttag ctagacctgc tggaatggct gtatcaatta tcactgaaga
    11941 aacagcgatt gcgaatttta aaaaggggaa atacgatcag gaaaaagtat ttgtcatcgt
    12001 gaaagagccg gaaacaatcc ttcatttagt agataacggt attagaattg accgactaat
    12061 tgttggcggt actgttgtta aagataatgc attacagcta tcttctagag cctatgcatc
    12121 agatgaaaat atcagcacgt ataaaaaatt gttggattct ggtgtagaaa ttgttacaca
    12181 atttgttccg gcggataagg cacaggaaat tcaatcaaaa ttaggataaa ggagtaagga
    12241 taatgcattt tactattttt caaattatta tgctgactat attagcattt attaaacatg
    12301 ttgattatta tgggattccg atgatctttg taaattacgc agttttttgg ggattattca
    12361 caggaatttt gatgggtgat ataaaaacag gtttgatagt tggcggtaca gttcaattga
    12421 tgtcattagg agttgccggt tttggtggct catctgtacc ggactatgga acgtgcgcaa
    12481 ttattgcaac ggcatttggt agccagcttg gagtagaagc cggattagca ataggactac
    12541 ctgtaggtat gttaggggtg caactagatg taattgtcaa aatcttaaat ggttttgttg
    12601 ttcgcaaatc acaggaatat gcgaataaac gagaatttaa gaaaatgaat agtgttttgt
    12661 ggttggggcc aattttcttt ggtttatctg cagcaattcc agtatttatt gccgttactt
    12721 taggacagtc tgctgttaat tacgttttgg atgttttacc taattggttt atggatgggc
    12781 taacattagc cggaaaaatg ttgcctgctg ttggtattgc gatgttgtta cgctttatgc
    12841 ctacaggtcg atacattagt tatttacttg ttggattttt cttagccgct tttttgaagg
    12901 tacctattat tggagcggcg atcataggat tcgctttagc atttaatgtg tatcatagag
    12961 ctgaaaaaga tgcacaaatc actgcttctg cgggagcttc tgatgttggg tttattgggg
    13021 aggatgaata aaatgagcga aaaatatcaa gtaacgaaaa aggatcttag gaaagcgaac
    13081 tatcgttggt tgatgtcagt ttgtaccttt aattatcaaa cacagcaagg tgcatctgtg
    13141 acttacgcat tgtcacctat tttaagaaaa ttatacaaag atgatgatga atacatcgaa
    13201 gctttaaata atcactttca gtattacaat acacagcctt ggctggcagc cattatttta
    13261 ggtgcttgtg ttgcaatgga ggaaaagcaa ggattagaag caaaagatgc gattaatgac
    13321 tttaaagttg gtacgatggg tccaattgct ggtattgggg actctctttt gatgacgatg
    13381 atcccaacca tcatgggatc aattgcggct tatatggctt tagaaaataa tcctgtagga
    13441 atctttttat ggttcatttt aatcatggta atcttctttt tccgaatgag aggctttgaa
    13501 tttggttata agcagggaat gaagattgtt actgaatacg gtgaaaagat taattattta
    13561 actgaagctg cttcagtatt ggggctaaca gtagttggat cattaattgc ttcagttatc
    13621 agtgtttcaa cgccacttaa attcactttt ggtgaagtta gtatgaaaat ccaaccaatg
    13681 ttggacaaaa ttttaccaac attaattcca gtaattatta ctgctgcagc atattatcta
    13741 ctcagtaaga aaaaaatcag tatgaccatt ttgattctac tcgttattgt ttttgcgatg
    13801 gttatggctg catttggaat attagcgtaa aggaaaagga tttgaattat gagaagattg
    13861 atcattgcta gccattcaat actagctgag ggttttaaag agacactaga gtttttaaca
    13921 ggtatgcata atcaaattag tagcttatgt gcatatgtcg aagaaattga tgatatagat
    13981 gaacaaatta aagagttagt ggatactaca gacgaaataa ttgttttaac tgacatggct
    14041 ggaggaagtg taaatcaaaa gttttttacc tatatttctg acagagtgca cgtaattgca
    14101 ggaatgaatc ttcccttggc aatgtcaatc gctttgcagt taggaaatga taatttagat
    14161 attggagcaa ttattgcgga ggcacaacaa caaatcatct atatgaataa tcaaaaaagt
    14221 gaagaaagga tagaggacga ataaaatgaa ttgtttaaat aatatatggc tccacaaggg
    14281 agaggaaagt agaactattt caccagaaaa taaaaatggt gaaaaaggga aagcggcaat
    14341 gacagcgagt catctaggaa ttgggagaaa agggtcacct tctgttccga taaatgctgg
    14401 agagacaatt actttagcag aaatggaagg ccctggaatt ttacgtcatt tttggatgac
    14461 agtgacagac aaaacaatcg ctgggagttt cgtcttacgt gatttaattt tgcgtattta
    14521 ttgggatgat gaatccactc cttctgtaga aagtccatta ggagattttt tttgtaatgg
    14581 gtttgggaca agatgcgaag tgaattcctt accaatcgta gtgaatccaa catcagggat
    14641 gaattgctat tttgagatgc catttcgaaa aaaagctaag attactttaa cgaatgaaca
    14701 tcctgagttt attaagcaca ttttttatac atttaattat gcattgactg aagtaccgga
    14761 tgatgcgatg tattttcatg ctaaatggaa ccgtgaaccc atcacgacaa aaggaaaaga
    14821 ttacaccctt attgatggaa tcaaaggcac tgggtattat gtaggaacct actttgcttt
    14881 gtgcgcattg gaaagatact ggtgggggga aggagaattt aagttttata tagatggaga
    14941 tgaagatttc cctacaataa catctacagg agcagaagat tattttggcg gcgcttgggc
    15001 tttccataaa aagaactttg gagaaagggc atatgctcaa aattttaata cgctatttat
    15061 gggctatcct tttcaatcta aaagagatca cacccgggat tattttagtg ctggaaaacc
    15121 taatccaaat ccagttcatg gttttggcga tgatgcttta ccgatgcatg ggttgtaccg
    15181 ctggcattta cccgacccca ttagtttcaa agaaaattta cgtgttactt tccaaaccct
    15241 aggaaatgat gacatcaagc tttatgagcg tcaagacgat atttcttctg ttgcctattg
    15301 gtaccaaaag gaaccacatg agtttttcga aaaactatta gacagggaag aacgaattcc
    15361 tagataaaag gacggtggag taagaaatgt atggctcaat agaagcaggt gggactaaat
    15421 ttgtttgtgc cattggcaat gatgatttaa aggttttaga aagagtgagt tttcctacaa
    15481 ctacaccgaa tgaaacaatg agtttggtaa ttgatttctt taatcactat aaagaacaat
    15541 tagaaagcat tggagtaggg tcatttggac cgattgatat ccatcgtgaa tcaaagacct
    15601 atggacatat cacctctact ccaaaaactg cctggaaaaa ttttgatttt gttggaacgt
    15661 tgaataagca tttcgaaatt ccaattgcct ggacaaccga tgtgaatgct gcttgttacg
    15721 gggagtatgt ttcaggtcat ggaaaaggtt tatccagtgt tgtttattac actgttggaa
    15781 ctggaattgg tggaggagct atacaagatg ggatttttgt tgaagggttt agccatccag
    15841 aaatggggca tacgttagtt aagagacatt caggagatac tttctctggt acttgtcctt
    15901 ttcatcatga ttgtctcgaa gggttggcat ctggacccgc tatcgagatg cgtacgggaa
    15961 ccaagggaca agatctttct atagaagatc cgttctggga aatcgaggcg gattatattg
    16021 cacaatgtgc ctgtaatacg accctgatgc tttcaccaga tattataatt tttggtggtg
    16081 gtgtcatgca acaagaacat ctgaaaaaga aagtacaaag acgtttttta gaactaatta
    16141 acggctatgt cgatacgcca aatatcgaag aatacattgt cacacctaag ttagcagata
    16201 atgcaggaac tataggatgc ttaactttag caaaagatgt tagaatcaat tcttaagcaa
    16261 aaaagtatta gtcaataaaa tgcttatgaa gtccgatcaa cttaatgtgg tcggactatt
    16321 tgtattcagc aatatcattc actcatgata cccagcgcct tatcataagt gatgcggttt
    16381 ttatcattga tcctaaaaat cttagcaaga caaaaagtac gtaagaaagt aaagactaaa
    16441 tacttcggag gaacaaatga ataacaatga taggttattg cgattgcgtt atgcgattga
    16501 tttgaaagat acggatttga ttaaagcttt tgagctaggc ggtgtaccac tgactaaaga
    16561 agaagctcag gcggtactga ccaaagtaca ggataagaac aaagataatg cagaaaataa
    16621 tgtgtatgaa aaaaccatca acaaccaagt ttttgacgca ttcctaaatg gcctgattct
    16681 cttggcgcgt ggtccgcaaa aagataagcc gatagtagac acgccgcaaa aaagcaagga
    16741 aatcaaatat atcaacaatg tgttgctaaa aaaattaaaa atcgccttgt ctatgaccac
    16801 tgatgatatt ttagacgttt ttgctgaggc agaaatctat ccatcaaaag gcgaaatcgg
    16861 ggcatttttg agaaaagaag gccaacgaaa ttttaagcct tgcggagata aatatatgcg
    16921 taattttctc aaggggttag gaatttataa tcggagaaaa gtataaagaa atttcatgag
    16981 aaatcaaaac aatggttgtt ttgatgagag ctagtttttg tatgagatta aaatattatc
    17041 ttaatcgagg agctggattg gttttatgaa tgatgaatat aagaatgatg aagataagat
    17101 gctttttgaa gagatagaga atcgatgtag gctcaatttt gagcttcggg gaaagatgtc
    17161 tttaatacaa caaaaaaagt atttagcgaa taaatcagag tttactctgg gacatgttga
    17221 aaaattaatc tcggattgga ttagtagtag aagcgaattt acaaaaataa aacagccgat
    17281 taaatttgac atgaaaaaac ttttgttaaa taagagtgag ataggtaata gagatcaata
    17341 tattagagct aaagggcaag aaataattga ttcattaggt gaaatgaggt catacaatta
    17401 tttgtatgta acacatagag ctgatggaat ggtcattact gtggggaaat cttcttctaa
    17461 tgatattttt ttagatggag atctttttta tcaactcaat acaaatcact tgtctggcac
    17521 tgaaaatata attttaagga cggaatatgg caatgaaata tttgcaaaat atgatgagat
    17581 tttaaaaaat tatttggact gggcttggat aattccggtt gagtcaggag atgctaagaa
    17641 actggagaga ttattgggcg atgaactaat taataaaaaa gtaccaattt taaattatta
    17701 ttcccataga caataaaagg ctatttttca tgataatact agttataact gtaaaaatgg
    17761 aagaaaatct gggaaagaag tttttaaata agtgtattgt tcgattttaa taaataataa
    17821 gcaataccat ccgtctgtgt tgcgcaacat cgtactacaa tgaatatttt ttcacaaaaa
    17881 gaaaatcatc catcgaatga atggaaggtt ttagtataca cgaggttaat gccccctctt
    17941 ttataatcag aggagtgagg ttttttctat gaatgtttct attttcttat tgctagtcta
    18001 gtttctctta cgatgaaatt gggattctat tccagttttt attgatttgc tgataaaata
    18061 acttgaatgg tggatataaa catgataaat aagagaagaa taacaaaaca aggttgtgaa
    18121 atgattctca aatgaatata atagaaagaa aaaggaggaa gaatcaatga aaatagcaat
    18181 tgcaggcgct ggcgcaatgg gaagtcgctt tgggttaatg cttcaccaaa gtgggaacga
    18241 agtattatta atcgatggct gggcagaaca tgtccaacaa atcaaagagc atggattaca
    18301 agcaaatttt aatggtaaag aggtagaagc aaaactacca atcgttcttc aatccgaagt
    18361 agaaaaagaa gatcaagttg atctgattat tctatttacc aaagcgatgc agctggaaaa
    18421 aatgctgcag gatatccaat cattaatcaa aaaagataca gaggtcttat gtctattaaa
    18481 tggtatcggg catgaagata ttattgagaa atttgtacca atggaaaata tctatattgg
    18541 aaataccatg tggacggcag gtcttgaagg tcctggtcag gtcaaattat ttggaagtgg
    18601 ttcagtagaa ttacaaaatt taggtgatgg aaaagaagca gctgcaaaaa aattagcaga
    18661 caaattgtct gaatcaggat taaatgctca tttttctgac aatattcact attctattta
    18721 tcgcaaagca tgtgtgaacg gaacaatgaa cggactatgc acaatcttag acgttaatat
    18781 ggctgagcta ggaaaaacat cgactgctca taaaatggtg gcgacgattg tcaatgagtt
    18841 tgccaaagta gcagcagtag agaagattga actagatgtc ccagaagtca ttgcacattg
    18901 tgaatcttgt tttgacccgg aaacaattgg gttacattat ccttcaatgt atcaagactt
    18961 gattaagaac catcgattaa cagaaatcga ttatatcaat ggcgcaattt ctagaaaagg
    19021 gaagaaatat ggtgttgcga cgccttattg tgatttcttg actgagcttg tccatgcaaa
    19081 agaagatagt ttgaacgtaa aataaaggag agattgaatg gaaacttcac aaaaaatatc
    19141 accgaaaatt tttctgaata aagtcctcgc tggtacagca acaggaatca ttattggatt
    19201 gattcctaat gcagtattag gtgccatttt aaaatatttt agtgcgtatc cctttgcggt
    19261 aacgatcgca cagttagcag ttatttttca actagcaaca cctttgatca ttggtggttt
    19321 gattgcctta caatttggat ttgatccgat gagaatgatg gttgtagccg gagcttcttt
    19381 tgttggttct ggtgtagtca aattcacacc tgatttgggt gaaacgggtg tttacgttgg
    19441 tgctggtaca ggcgatatta ttaatacgat gctgacagca tcgattgctg tcgggctgat
    19501 tttactgatt ggaaatagtt ttgggtcagt gtcgattgtg ttaacaccga ttgttgtagg
    19561 tgtaggtgca ggtttacttg gtttttattt attccctttt gtaacagcaa ttacttctgc
    19621 aattggatca ttgattaata acttcactac cttacaaccg ctgttaatgt ctatcttgat
    19681 tggttgttcc tttgcctttt tgattatctc tcctatttca acagtagcaa tcggaatggc
    19741 aatccaacta gatggtgttt ctgctggtgc ggctgcgatg ggcgtagctg caaccacttt
    19801 tgttttagta gtgaactctt ggaaggttaa taagtcaggt gtgacaattg cgattgcttt
    19861 aggcgctatg aagatgatga tgcctaatct atttagaaaa cctgtgattc ttattccttg
    19921 tttagttagt gcagtgatta cagctattcc tgtcgctcta ttttctattt caggtacgcc
    19981 tgcttctgct ggtttcggcg tggtcggact tgttggtccg ttggcttctt tagatgcagg
    20041 gctaaatggc tttcttgttg ttctttgttg gttagtcatc cctgtttttg cggcactaat
    20101 tactcaattt ttatgcgaga aagtatttaa actgtatgat cgagaagaag tcttcaaatt
    20161 tttaggctag tagattttac taagaaattt tcaatcaatg gatgcgtaag tgagatgtca
    20221 acaacatctg acttacgttt ttttgccttt ttgagtagga gattgatgct gacaactgaa
    20281 ctcttcagtg ccattcgatt ttttaaaatg tagaagaaac tcacctttat gttattgatt
    20341 gttcaaaagg caactagaat aaaaatatgt gttaaaatga gaaaaaattt gattgttgga
    20401 tgtatcgaat aatcactaaa aagtaggaga agaaaatgat ttttttgcaa aaatatggtt
    20461 tttatttttt attattaggt gtgattagtg atttatcgac accgtatatc cttggccttt
    20521 tttatcccaa actgaatcaa atgactaccg taattagtgt gtttggtgac gtagatagtc
    20581 cagtcagacg tgctttcttg gtctggtcag ttgtatctgg actttttttt gttctttcgt
    20641 tgcctgcgtt gtatcaccta tttattggaa catcaaaaac acttgcaata cttgctgttg
    20701 caacagttgg tttatatggg ataggtgatt gtatttttac tgggttattc agtatcaata
    20761 cgaatgaaag ctcttggaat ctatcgactt ggatccataa tataggttct gggctaggct
    20821 atgcaggctt tctacttttc ccattgttac ttgttctgct ttatcgtcaa agtggtcaag
    20881 gtacgcttag ccatttttat cttgttttaa cagttattag tttactaatt gcaggtcttt
    20941 acggattagc acggattccg tcgattagtc agtttgcctt ctttaagcaa ttgggcttct
    21001 ttcaacgctt aagttttttc tttaactatt tgccgatgat ttgtttaagt ttttttcaac
    21061 tacgaaagta gaaaaagcag tgtgaagctg attaagtaaa agaatttctc tatgggtaac
    21121 cattcgtgtg gatgtgttcg actaagaata gagatgagga gagcgaaaag caagttagtc
    21181 ttaacttgtt atgcgttgtg ctaaatttca ggtagtcatt ttttgaatga ataagaagaa
    21241 aacttgaaag agggtgactt catgttagat gtggagcaga tggaaataga cctttataat
    21301 attattttaa atcgaaatac aagagaatgg gaaagaacac aatttgaaga ggcaaaagaa
    21361 gacctagcaa aaatgtcgat aaagcaggtg atagaaaaac tagaggtcaa cttgcgtccg
    21421 ctagcactac gagataattt gacaccagat gcgatggatt tttatttaag aatcacaggg
    21481 gagtcagcga gtgcaaaggc ttatgattat gccaaacata agataacttc acccttatac
    21541 caagaacggg cgatttttgc cggtggctgt ttctggtgta tggttgagcc ttttgaaaca
    21601 aaaccaggtg taatctcagt gttatctggt tatacaggtg gagagaccaa aaaaccaaat
    21661 tacgatcaag tcagtggtgg atatactggg catgttgaag ctgttgagat catatttgat
    21721 acacgtcaaa taacctatga agagctgttg gagatttatt ggcaaatttc agaccctaca
    21781 gatgcctttg gtcaatttca agatcggggg aaacaatatc gttcaattct atttgttgtt
    21841 aatgaaaagc aaaggcaatt ggctgaaaaa tcaagagaac aactgattca atctaaccga
    21901 tttagccgtc ctatcgttac agagattcgc caagcaaaga ctttttggcc agctgaaaat
    21961 catcatcaac aattttatca gaagcaacct aaaagatata aaaagatcaa gcattcgcat
    22021 cagcttcatt tattttttca gcgacataga tagaggaagg ttgtggcgca aagcgttcag
    22081 ctccgacaaa ataatgagca actgacaaaa atagcttttc atatttttgg acagttatga
    22141 attatttcga ggagttgctt tgagaacacc gaggaaaagg ttgtggcgca aagcattcag
    22201 cttcaagtcg caaggaaaca ggaggtatga caagtctttt gtcacaactc ctgttttttt
    22261 actagccttt atttccatgt gaaagagaat tcgaattgta gaatcttgat ttttctatgg
    22321 aattttgtag agaatcatct tgataattaa tagacaccta atcgaattcc acattaatga
    22381 tgaactaaat tccgtataaa agcgcaaaca ataactata
//
LOCUS       DADGHT010000044        22030 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.044, whole genome shotgun sequence.
ACCESSION   DADGHT010000044 DADGHT010000000
VERSION     DADGHT010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22030
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.044"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(27..1259)
                     /locus_tag="JX887_001507"
     CDS             complement(27..1259)
                     /locus_tag="JX887_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAX1257502.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1514..2083
                     /locus_tag="JX887_001508"
     CDS             1514..2083
                     /locus_tag="JX887_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1257503.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2261..2701)
                     /locus_tag="JX887_001509"
     CDS             complement(2261..2701)
                     /locus_tag="JX887_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAX1257504.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2859..3623
                     /gene="map"
                     /locus_tag="JX887_001510"
     CDS             2859..3623
                     /gene="map"
                     /locus_tag="JX887_001510"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAX1257505.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3655..4578
                     /locus_tag="JX887_001511"
     CDS             3655..4578
                     /locus_tag="JX887_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAX1257506.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4803..5042)
                     /locus_tag="JX887_001512"
     CDS             complement(4803..5042)
                     /locus_tag="JX887_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1257507.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5047..5466)
                     /locus_tag="JX887_001513"
     CDS             complement(5047..5466)
                     /locus_tag="JX887_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1257508.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5693..6931)
                     /locus_tag="JX887_001514"
     CDS             complement(5693..6931)
                     /locus_tag="JX887_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004081244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1257509.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7038..7673)
                     /locus_tag="JX887_001515"
     CDS             complement(7038..7673)
                     /locus_tag="JX887_001515"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1257510.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(7787..7879)
                     /locus_tag="JX887_001516"
                     /pseudo
     CDS             complement(7787..7879)
                     /locus_tag="JX887_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(8015..8650)
                     /locus_tag="JX887_001517"
     CDS             complement(8015..8650)
                     /locus_tag="JX887_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1257511.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9162..10304
                     /locus_tag="JX887_001518"
     CDS             9162..10304
                     /locus_tag="JX887_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAX1257512.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10297..10503
                     /locus_tag="JX887_001519"
     CDS             10297..10503
                     /locus_tag="JX887_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAX1257513.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10582..11775
                     /locus_tag="JX887_001520"
     CDS             10582..11775
                     /locus_tag="JX887_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAX1257514.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(11782..11940)
                     /locus_tag="JX887_001521"
                     /pseudo
     CDS             complement(11782..11940)
                     /locus_tag="JX887_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788611.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-binding domain-containing protein"
     gene            11980..13119
                     /locus_tag="JX887_001522"
     CDS             11980..13119
                     /locus_tag="JX887_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAX1257515.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13112..13912
                     /locus_tag="JX887_001523"
     CDS             13112..13912
                     /locus_tag="JX887_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1257516.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13912..14739
                     /locus_tag="JX887_001524"
     CDS             13912..14739
                     /locus_tag="JX887_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1257517.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14717..15451
                     /locus_tag="JX887_001525"
     CDS             14717..15451
                     /locus_tag="JX887_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1257518.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15551..16417
                     /gene="rfbA"
                     /locus_tag="JX887_001526"
     CDS             15551..16417
                     /gene="rfbA"
                     /locus_tag="JX887_001526"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAX1257519.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16431..17003
                     /gene="rfbC"
                     /locus_tag="JX887_001527"
     CDS             16431..17003
                     /gene="rfbC"
                     /locus_tag="JX887_001527"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAX1257520.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17025..18053
                     /gene="rfbB"
                     /locus_tag="JX887_001528"
     CDS             17025..18053
                     /gene="rfbB"
                     /locus_tag="JX887_001528"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAX1257521.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18151..19002
                     /gene="rfbD"
                     /locus_tag="JX887_001529"
     CDS             18151..19002
                     /gene="rfbD"
                     /locus_tag="JX887_001529"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAX1257522.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19036..21069
                     /locus_tag="JX887_001530"
     CDS             19036..21069
                     /locus_tag="JX887_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257523.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21113..>22030
                     /locus_tag="JX887_001531"
     CDS             21113..>22030
                     /locus_tag="JX887_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAX1257524.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHN"
BASE COUNT         6962 a         3935 c         4352 g         6781 t
ORIGIN      
        1 ttttttgcat gtgtgcgaaa gtatactcaa gcccaatcgc catttcggaa aatcggtact
       61 gtagagccat cttcacggat tccgtcgata tccatcttgt cagatcctac catgaaatct
      121 acgtgggttt gacttctatt caatccagct tctgctaatt cttcatcgga catttctgta
      181 ccgcctttca cactgaaggc ataagcagaa cctagtgcta agtgattcga tgcgttttca
      241 tcaaataatg tattgaaaaa gatgatgcca gattgagaaa taggtgaagg gtcaggtaca
      301 agtgcgactt ctcctaaacg acgcgcacct tcatctgtat caagcagttt tgctaagaca
      361 tcttctcctt gttcggcaga aaaatcaaca acttttccat ctttaaaagt aaatttcata
      421 cccgagatga tggtgccagc ataactcagt ggctttgtac ttgaaatgta accatctact
      481 cgatgactgt caggtgctgt gaacacttct tccgtcggca tatttgccat gaatttttct
      541 ccacgagcat tatagcttcc agcgccttcc caaagatggt ttttaggcaa tccgataatg
      601 atatctgtac cgggagcagt atagtgaagg gcagaaaatt gttctcgatt caattcttct
      661 gctttttttg ctaatttttc atcatgcttc ttccatgcta agacagggtc ttcttcatag
      721 acacgagtcg ttttgaaaat ctgatcccat aatgcctcaa cttgtttttc ttctggcagt
      781 tctgggaaga cttttgctgc ccattgttta ccagccgcag ccacgacagt ccaactgact
      841 ttatttgctt gagttgcctt gcgtaaattc attagtgctt tgccattcgc tgattgataa
      901 gacgctactc gatggctatc tacaccagca aatgcatcgg gatcggcaga aacaacgctg
      961 atcctgcttg ctcctttttc aagccattca tccgcttgat cgattttaga ttgtggtaca
     1021 ttctcaatac gatccgttgc agcatgtaaa agaaattctc tttggatctg gtcgtcagtc
     1081 cattgaacga taacctcagc ggctcctagt ttataagctt cttgtgtgat caatcgagca
     1141 aggggtgcct gttccacgct gatctgtaaa acaactgtgt gtcctttttc tgtggctacg
     1201 ccagtttctg caattaagcg tgcatatttt tttagaagtt cattaaaatc agataacata
     1261 ataaaaattc ctcctcacca ttttttctgg taactattag catgatacca tttaattatg
     1321 attcaaacaa tgaggcttta aataaaaaaa ggaggttatt tttttaaggt taagtttcat
     1381 gatatatgtt actacttgct atttcagctt gtgaagaaaa tcaaaaacta attttgcata
     1441 tcaaaaaaaa catgttacaa tgaaattaat caatggtgga agcgttataa aaaaattaag
     1501 gagattaaaa aatatggcaa gaaaaaagac gattactaga gaacagattt tggcagctgc
     1561 ttatgaagta gctgccaccg atggatttac acgatttact gcgagaaaca tcgcgaacaa
     1621 aatgaattgt tccacgcaac cgatttatct tgagtttaaa aatatggatg acttgagaca
     1681 agctcttttt gagcagatct atgatcattt acaatatgaa gtgttcactg ttgagcatac
     1741 agggaatacg attatcgatc ttgcttttaa ttatatccat tttgcaagaa gagagaagaa
     1801 gttgtatcgt tcactgtact tagaagaata tggtggagga aaagagatgc agaatttctc
     1861 ttatacttac tttgtgaata cagtgaaacg cgatccagct tatgtgaatc tttcagaaga
     1921 gcagatcgaa tctttgtata atgggacatg gatcatagct actgggatcg cagctttgat
     1981 gtcttcaagc atcatccatc caactgatga acagattgaa aagatgatcc aagacagtat
     2041 agatgctatc ttgaaattca aagaaccaat cgaaatcgat tgaatatact caaaagttcc
     2101 acaaatcagt aggtaacaag agatgtgtca aaataaggaa aagttcgttt ttcttacagc
     2161 gtatgcattt ttaactcccg aagaactctt ccatgaatgc aatgaataaa agagccatac
     2221 agattgaata aatctggatg gctcttttat tgcaagtata ttaaattttt gcgactagtt
     2281 ctttagcgaa agcttctaaa ttttcgatat cttcttcttc agcattcaga tccactttaa
     2341 cattttcggc tccttttgat gcgcctgttt ttgcaaaagc agcatcgaaa tcatccaccg
     2401 atttgcagaa ttcatcgtaa aaagtatcac cagatccgca gacaccgtaa atttttccca
     2461 atagatccaa ttcttgcaag tcttcataaa agtctacgat ctcatcaggc agatcgccat
     2521 catcgtatgt ataagtagct actacgcaaa tatctgcctc ctcgaattca tctgcatcta
     2581 cttgggtaca ttcgttgatt tcgacttcga tatccagatt ttcaaatgct tctgcaacaa
     2641 tatcggcgat ttcttcagtg tttcctgtca tgctagcata tacgattttt gctaaagcca
     2701 tgatgtgcct cctcgtttat aattatttaa caattatgaa ttataccaaa acatcattga
     2761 aaagaaaata aaacctagag acacctgggg aatgtcattt ggctaaatgt atgccgctat
     2821 gttaaaatga gagggatttg taaaaaggag acgaaaatat gattacttta aaatcagcac
     2881 gtgaaattga aatgatggca gaatctggag ctttattagc agatgtacat aaaaatctgc
     2941 gtgattttat aaaaccagga atcacaagtt gggatattga ggtatttgtc agaaactata
     3001 tcgagagtca tggcggaatt gctgcgcaaa ttggctttga agggtatgaa tatgcgactt
     3061 gtatcagtat aaatgatgaa atttgtcatg gattccctcg taaaaagcct ttgaaaaacg
     3121 gtgatttggt aaaagtcgat atgtgtatcg atttgaaagg cggcatttct gattcttgtt
     3181 gggcctatgt agttggagaa tctacacctg agatcgaccg attgatggaa gtaacgaaga
     3241 aagctttgta catcggtatt gagcaagcac aagtagggaa tcggattggt gacatcggtc
     3301 atgctatcca aacttatgta gaaggcgaaa atctagcgat cgttcgtgat tttattggtc
     3361 atggcgttgg tcctacgatt catgaagaac cagcagttcc tcattacgga gaagctggaa
     3421 aagggttgcg gttgaaagaa ggcatggtta tcacgatcga acctatggtt aataccggaa
     3481 cttggaaaat gaaaatggat cctaacggct ggactgcgta tacaagagac ggcggacttt
     3541 cttgccaata tgaacataca ttggctatta ctaaagatgg tccaagaatt ttgacatcac
     3601 aaggagaaga aggcacttat tgatctatcc agtcaatagg tacgggagag gtacatgaaa
     3661 gtttggaaca aaataaaaca aaatgaaaat ctgatgcgct ttattgagac gactcaaaag
     3721 cgcatcactg attcagaaat gagtacgacc tctgtcgtcg ttgcttatta tttactcttg
     3781 tctttatttc cattgattat tgcttttggt aatattttac cgtttctcca catcgatcaa
     3841 gagactgtac tgacctattt acgagaagtg attcctgaga ccgtttacca gtttatcggt
     3901 cctgcaatca aagacctttt gacacaaagt tcaggaggct tgttatccgt ttctgcatta
     3961 gcggctttat ggtctgcaag tcaaagtatc aatgctttgc aaattgcgat gaataaagcg
     4021 tatggcgtag aaaatagaaa aaattttttg atcgtccgtt tcttctcact aattgtcatt
     4081 gtcttgttca tgattgctat tagtggggta actatcgttc ttgggttggg acagctgatt
     4141 ttggatgcta ttcagccaat cgtacaaata cccgtgaact ttatcgatca gttccaaact
     4201 ttgaagtggc caatcacatt ggtagcttta tttgtcatca tgttcttgat ttatttaatt
     4261 gtccctaatg ctcagttgaa gttgaagacg atcattccgg gcacgatctt cgctactgtc
     4321 ggctggatgc tgttatcaca agtgtttagt atctatgcta ggtattttgc aacgaggatc
     4381 agcggttatc agatcatagg aagttttatt gtactcatgc tttggcttaa ttttgctgct
     4441 acgatcatca ttttgggcgg aatcatcaat gcagttgttc aagaatacgt gacgggtcat
     4501 caaatcaaaa aacgtcgaga tccaagccga aaatggttca ataaattgaa aactaaattt
     4561 tctcataaaa aaaagtagaa acaagagttc ttattgtaaa tttatatcag taatttattt
     4621 gaaattttat atctaatttt caattatccg cataaacact atacattcaa gcattttgaa
     4681 gtatagaaaa acactcatct taccacgaat ttaccacgat tgaatgagcc ttgatatgac
     4741 cgtaaaacta ctaagggaga tagcacgaaa ctgtgtatct cccgattttt ttatacagtt
     4801 gattacttca ctccgatttc aaatttcaat attgctttca tcatgtctgt atgaatttct
     4861 ccttttagtt cttcatcaac ctgcataatg attttaccac tttcagagtg gtaaaaagga
     4921 cgcaagcata atttagaaat ataaccgtca taaaacttca aaatctcttt aactgccatt
     4981 tcatctccgc ttgacgcttt gcaaatcaat tcaaaagagg gatagccata atctttactc
     5041 atttctttac ttcctttcgc tcaaaagcat ttttaacttc cttagtcctc tagttcttct
     5101 actgcaaata gcagaacgtg atacatggta cagttctgaa atttctctgt cgttcattcc
     5161 ttgaaaataa cgtaataaaa tcgcactacg ctgtttttct gacagtctat gtaaaactgt
     5221 accaagtgtt tcatcagata cataaattgt aaagtgcaag actttaaatg atacacaatc
     5281 ataaaaacag gtatcaatcg ttccacgttc aacttgtttc gtttcggcta tttcacaaaa
     5341 caatacttca cgtttagaat gtcttgcaag ctgtctgttt cgacttttca ctttgttctt
     5401 aatgacaatc agcattaaag aattgaactg taatctgacg atatgctcga aagaagatgt
     5461 cctcataatc tcaccccctt tctgctaatg ctgaaatata taaacggaat accgtttata
     5521 ccctttagaa atacagaaaa atggtaagaa aaaagcccac acaaaacata tatttgtgcg
     5581 agccttaaat actgcaatat tactctttct tttataacac tatcctttta gcagatttca
     5641 aattttcttt tatatattgt ttttagccta acatactatt taaccccttg tattatatct
     5701 ctaacttttg aaaaattctt tttgaatata ttgaaatcat gattgaagca atagaagcta
     5761 caaacataac aacccatgtt tcttgtataa atacatcgaa taaaataccg taaaccattt
     5821 gtccaatagg ttgaccgcac atagcaactg ctaccagcgt agccattatc tttcctacta
     5881 attgcggtgg tgtttgtgtc tgaacaagag tgtaaatttg aacaacaaac atagtagata
     5941 cacccatagc cacaaagcac atcactgtaa ctacccagta ggaaactatt gcaggcaatt
     6001 ctaaaaatag cgaaattccc ataagtaaaa cagaaacaga acaaataagt aacaaggtat
     6061 aaaggttttt tagttttaac tttgaagcaa caagagctgt taaaatacca ccacataaac
     6121 cacctaatga taatgctgat tgtgaaaaac catatagtgt atctggcatt tttaaaactt
     6181 cagaaattaa gataggcaga ccaacaatta aaacagcact taaaaccaaa ttgaaaatgc
     6241 aaaccaaaaa gattacggat ataaaaatgg gtttctcctt tttcaaaaag gtataactat
     6301 cttttaaatc gtttttagca actgcaatta cacctacttc acgaggtctt ttttggtgtg
     6361 gaatatggat aaaaatttcc ataatggctg aaaaagtaaa acatataata ctaacaatta
     6421 aaatgggatt gataccataa aattgaaaaa ctactccgct tatagctggt ccgataaagt
     6481 ttgctaaagt atttacttga tttattatag cattaccgac ggtaagttta tctgatgata
     6541 ccaatagagg aatacttgct tgtaccgctg gttgatatgc accagaaata ccataaagta
     6601 acatcaaagc aacaataaac aaaggtatga taggaatttt tcccaatgac aaataaaata
     6661 ctaaaattat gattgctgtt acaaaatcta gtatgaccat aatgtttctt ttatttgtcc
     6721 tgtcagcaat aataccacct accagcgaca aaataaccat aggtaaaaaa gagcaggctg
     6781 tagcaatacc aaacaaagct gatgaaccag tttcttttaa caaatagtac ggtaatgcaa
     6841 atcgtaggat agcgtttcca aataaagaaa ttatctgtcc tataacaaca agtataaaat
     6901 cacgattaaa aagttttttt tctgcttgca taaaatctct cctttttatt taatcaaaca
     6961 gaccgtcggt ttatataatg gtttaaataa actgctcttt tatagagcag tctatcgtat
     7021 agggataaca aatacagtta tttacaaaac tgtataaatg cagaaattgt ttcttcgtct
     7081 aataatgtgt ctatgcctat tccatttaaa agggcattga atgtattgca acgtttttcc
     7141 ataccctctt tatccgtcat ttcaactaat gggttgagcc atacattact taataccatg
     7201 ataacttctg caatttcatg tgaattttca atctccaaag acttatcctt gataccttgt
     7261 tctaaaacgg gttcaacaaa ttcaggtact acaatttcat acatttgttc tatttgcata
     7321 gcaagaaaac gaggattgtt taatagttga ggagaaactg tcaataaaac gctttggtta
     7381 gaattgaata ccgctgtctt aaatatttct cttaactttt ctaaaccgtt taaactatcg
     7441 ttatctctaa ttttagcaaa tattactgca ttttcatttc caattctttg aaaaattgct
     7501 tttaaaatat cttcctttga atcgaaatga tgataaatag cacctttaga aagttttgtt
     7561 tcattgataa tatcttgcaa tgatgtgtta tcatatcctt tttcacaaaa catttttgta
     7621 gaaacatcta aaatgagttt tactgtttct tctggatatt tatttcgtgc cataacttac
     7681 ctccaataca aaccgttggt ctgattaaag tatatcttag tattttatgc ttgtcaatat
     7741 aaagacttgc aattttataa aaatgcagaa tgcaagcctt tttcatttat tctacaatct
     7801 tccagttgct ttccttatgc ggtgtcaatt catactgtga tacctgcgtt gcctttgcct
     7861 gatttaccac aaatcagatt ttatcccttt cttcctcttg attgcccaca acagaaaaga
     7921 aaaagccctg tcaagagctt tgccaccatt ggtggtgctt tgcactcttg atcgggcttt
     7981 ttgtttgctg tatcttctcg caagaggaaa aaagttactc gtcctcatca tcaaaattgt
     8041 tattccttaa tacttctcgt aacagttcca tatcttcttt tgagttcggg tttatcattt
     8101 tcacgacttg ataaggtgtc ttatacttat gtccctctat gctttcccca aacatatcca
     8161 tactgtataa atcatcatag cggtctaata atttttgaaa cttcaaatgc tggataaatt
     8221 ctttgattgg gtaaaggtcg gacgcttcaa tgcttttccc gttgatatag tctgtaatat
     8281 attcccgtaa cttttctaac tcatattcca gccattcttc ctcgctgtca aagaagttat
     8341 catagtgtcc atgtttcagt tctgcattta gacgttcttc ggctcttaaa aactgacaga
     8401 cttccttttc agattgattg acatacttcc attctcccga caacaattca ttgggcgtaa
     8461 cgtccagcac ttccattatc ttttccagcg tttcataggc aggatagttc aaccctcttt
     8521 caatcttgga aaggctctgc atattgatac cgattttgtc cgcaagttcc tgttgtttca
     8581 ttcccctaaa ttttcttatg gtctgtatat tatttcctaa atggcttatt ttcattgcat
     8641 aaccctccat atctcgttat atcttcgcta ttataagtct atcatgctta atatgatttg
     8701 taaaggcaaa aaaagatatt gacaaataag catataagaa ttactatgtt cttgtaatcg
     8761 aataagcaca atagaatgaa atataaaaac attcaaaaag aaatacctat ctgattaaat
     8821 ccgtagatat gaatatcggt tgaaatggaa cttgttagaa aaggcaaaac agaacttgct
     8881 gacaaagtat ttctgacacg gtggcggaag cctctcaggc ttaccgccat gacaccttgt
     8941 gtcaagggga agaaatgctt tgtcggctgg cgagcctgcg agccttgtct gtgcccccgt
     9001 tatctaacag gggggcacta tttcacaaaa gacaagtcaa aaaccataca cccccaaacc
     9061 tgtgagtagt aatgagaggt tttaagaaga tagtacatat cacacttttt gaaaggtggt
     9121 ttacaggtat ttcaaggcta ttgtgggatt ggaggaatac aatgaacaat ttagaatttg
     9181 cacttgaaat gaagaacaaa cgtcttgcca gcggtctttc acaaggagaa cttgcaagtc
     9241 ttacccatgt atcaagatat agtatcaacc gctttgagaa cggaaaagct aacgccagca
     9301 aggaaacaca gaacattatc ctgcgttgtc tgaattacta tatctgcgat aagccttttt
     9361 atctgctcgt tgattatctg tctgtccgtt ttccaacgac tgacgcattg gaagttatcc
     9421 gaaaggtgct tggcatgaaa gcagattatt ttatccatta tgactatggg tattatggct
     9481 ataaggagca ttatgcttac ggggaaatca aggtcatggc ttctgatgat gaacacatgg
     9541 gcgtattttt agaattaaaa ggggcaggct cacgcaacat ggaatatgtc ttacaggcac
     9601 agaacaggga ctggtattca ttcttaaacc gctgtcttga ctgtggcggt gttatccgac
     9661 gttttgactt ggcaatcaat gatatgtgcg gtctgctgga tattcctgtg ctatctgaaa
     9721 aatacagaaa tggtggtgcg gaatgtcgct gtaaaaacta tgaaaatgta caaggtggaa
     9781 aattaagcgg aaaaaaccgt aatttagcaa gtacccttta tatcggctca aaggcaagca
     9841 caaaatattt ctgcctgtat gaaaaacaaa aggaacaggc aacgaaaaag aaacataccg
     9901 atattatcaa ccgttttgaa attcgtctgc gtgacaaaaa ggcggtacag gcagttgaag
     9961 aactgttatt gacgtataac cctcatgggc tggtgtttta tctcattacc gattttgtgg
    10021 aatttcctga ctatccattg tgggagatat tcatttccca tgacagttta ccttttgaaa
    10081 tgaaccctgt acctgtcaat atggaacgca ctctgcaatg gctggaaaga caggtcatgc
    10141 cgtcaatcgt gatgatagag gaaatcgaca ggctgacagg ttcaaactac atgaaaatga
    10201 ttgatgaatg tacccacctt tctgaaaaac aggaaatgct tgtggaacag atgtgtacgg
    10261 acatatcaga cgtaatcgaa agtgaggggg tgttttatga gtaatacaca ggatattccc
    10321 gtatgggaaa aatacaccct taccattgaa gaagcgtcaa agtatttccg cattggagaa
    10381 aacaagttaa gacgattggc agaggaaaac aaggacgctg gctggctcat tatgaatggc
    10441 aaccgcatac agattaaacg ccgacagttt gaaaaggtta ttgataaatt ggacgcaatc
    10501 taatgcaaat gagccttgta tgtgttatga tgaacacaag tcatatcaag gctctttcca
    10561 acaaggaaag gagcagacac catgaaagaa aaaagacggg ataacaaagg tcgtatcctg
    10621 catactggag agagccaacg aacagacgga aaatacttat ataaatatgt agacgcattg
    10681 ggaaacacaa aatatgtgta tgcttggaga ttgacaccca cagacccgac accaaaggga
    10741 aaacgggaaa aaccctcact tcgagaactg gaacagcaga taagacggga tattgaggac
    10801 ggtatcgaca gcacaggcaa gaaaatgacg ctttgccaac tctatgccaa acagaacgca
    10861 cagaggacaa atgtgaagaa aagcacacag aaacaacggg aacaactcat gcggttatta
    10921 aaagaggaca agttaggtgc taggagcatt gatacgataa aaccctctga cgctaaagaa
    10981 tgggcgttac gcatgaaaga caaaggcttt tcctacaata ccattaacaa ccataaacgc
    11041 tcgttaaaag cgtcattcta catagccata caagatgatt atgtgaggaa aaaccctttt
    11101 gatttcaagc taagtgaagt catagaaaat gataccaaag agaaagtcgc attgacagag
    11161 gaacaggagc aagccttatt gtcatttatt aagacggaca acgtgtatca caagcattat
    11221 gatgatgtgc tgatactgtt aaagacagga cttcgtatct cggaactgtg cggactgaca
    11281 gtagccgaca ttgatttcaa gaatgaagtt gtgattatcg accaccagtt actaaagagt
    11341 aaggaacagg gctattatat tgaaacgcct aagacgaaaa gcgggataag gcaagtgcca
    11401 ttaagcaaag aaacgataca ggcatttcaa cgggttatca acagccgacc aaagataaag
    11461 tcgatagagg tagacggaca cagcggtttt gtgtttatca atccgaaagg taatccaaaa
    11521 gttgccattg attataacgc cttatttatc cgtatggtaa agaaatacaa caagcaccac
    11581 aaggacaatc ccttgccaca tattacaccg catacgctac gccatacatt ctgcacaagg
    11641 ctggcaagca agaacatgaa cccgaaagat ttacagtata tcatggggca ttcaaacatc
    11701 agtatcacaa tgaactggta cgctcatgcg tccatagata ccgcaaaatc agaggttcag
    11761 cgtctaatcg catagaagta tttaccacga ttttaaccac gattgacagg gaaaatataa
    11821 gaagatagac ctagatatgc gaggtttacc acaaaagcaa aatgcccgta gagccgataa
    11881 aataaggctt tgcggacatt tgagaagata taaaaagata gtcaaaaaga catatataat
    11941 ttataataat tatgactctt aattaaagta ggtgcccata tgcttgtttc ttttagtatg
    12001 gttataagat tttttctgac aattttatta tcactgatat taacacctgt attcaaaatc
    12061 atttcagtac aaacaggtat ggtcgacaaa ccaaatgaaa gaagaataaa taaagttcca
    12121 atgccttcag cgggcggact gcctatcttt atttcatttg ttatatcgac tttattctta
    12181 ttccgtaaaa ttatccctca atcgtatatt gtaccgatct tgattgcttc tttagtaatc
    12241 atagtcacag gagtgctcga tgataaatat gagctgacac ctaaacaaaa aagtataggg
    12301 atcttgattg cttctcttat tatttatttt gtagcagata tacgtattga ttccttcacg
    12361 cttcctttta ttggatatat ccaactaggc tggcttagtt ttcccgtaac gattttttgg
    12421 atcttcggta tcacgaatgc ggtcaatctg attgacggtt tggatgggct ggcggcaggg
    12481 atttcattga tcggtttaat tacgatagga atcattggat attttttcct ccatgcttct
    12541 acagtgtata ttccagttgt tattttctgt cttgtagcaa gtattatcgg tttttttcct
    12601 tacaattttt atccggcaaa gatttattta ggcgatacag gagctctatt cctagggttt
    12661 atgatggccg tcctttcact acaagggctg aagaacgtga cttttgtttc atcgatttct
    12721 ttgctgatcg tcatgggagt gccggtaaca gacacgtttt ttgctatcat taggagaaaa
    12781 gcaaaccgtg tttctttttc tacagcagat aaaaaacatc ttcatcaccg actaatcagt
    12841 ttaggcttta ctcataaagg tgctgtcctg acgatttatg cgatggcttt gatgttttct
    12901 ttcacagcta tggtcatgaa ttatactgga agaatcggaa cgatcatatt gattattgcc
    12961 atgttgtttg ctgcaatttt attatttgaa ttgattggtc tgatcaatga gaaacatcag
    13021 tttattttaa aaacattgcg atttttaggg aataaagagt accgtacgca agtaaaacag
    13081 aaatatttga agaaatggaa ccgtcatata gatgaataac aaattaaacc agccgatcct
    13141 tattagtatt gtgacggcaa acagtgataa aatttttcgg acactagata attttatttc
    13201 aactgtaaaa gatgaaacag cagtaaaaat ccgaattttt gacaacaatt cacttcccga
    13261 gtacaaaaaa agactaacag agtataggaa atatccctac atcgatatct attttcatga
    13321 tgaaaattcc ggatttggtt atggacataa tcacaatctg atagctagcg attctcgcta
    13381 tggcattatt tgtaacccag atattttagt ggatgaagag acagttacag cattggtctt
    13441 gttattgaaa gaacatccgg aatgtgcgat gttagcacct aagattctta atgaagatgg
    13501 aacaactcag cacctcatcc gtgagcagct ggctgttttt gattacgttt tgcgctttgt
    13561 gcctttcaaa tgggtcaaaa aaaagtttga caaacgactg gctgtgtttg aatgccgagg
    13621 attgcctact gatgctaata gttatgtacg gatgatctca ggtagtttta tggtagctga
    13681 tattgataaa tttaaagaga taaaggggtt tgatgagcgt ttcttcatgt actttgaaga
    13741 caacgacttg tgtttgagtt ttgaaaaagc aggttacaag ttattgtaca caccctttta
    13801 tgcagttatc catttttacg ggaagggtgc gcatcgaaat gcaaaactgt ttcgcgtgtt
    13861 tttgacttct atgatgaaat ttttcaataa gtgggggtgg cgttttttct gatgaaacca
    13921 gaaatattag tagtcgttgt gctttatcag caactattca gtcaatctcc agcttatgga
    13981 ccattaagca aagcacttag cgaaaagcaa attcagctta ttatttacga taatagtcct
    14041 caaaggcagc aaaatgagct gtttgaaaaa gaaaatatcg tttatcatca tgatccgcaa
    14101 aatcctggtt tagcggtggc ttataatttt gcgttgtctc aagcagatga aggaacacgt
    14161 tgtctcgtca ctctggatca ggatacgagg ctagtcgacg attattttga actattgcgt
    14221 aaagtaacct ttacagatga atgtgttgct gcagttccga tgattttttc tgggagccga
    14281 caagtttctc ccctatattc agatcgttat atcaatcgta cagctcaagc agtagaagtt
    14341 gaaggcccaa cagctgaacg aatcatggca atcaattcag gtgttgcctg gtctgtcaaa
    14401 tttctaaaaa agattggcgg gtttaatcct gctttttctt tagatttttt ggatcattgg
    14461 ctgttttgga aagtggatca gttggaaaaa actgtggaga tccttcctgt acgaatggaa
    14521 catgatcttt cggttttaga ctatgaaaaa gtttcaagta atcgataccg ttctatttta
    14581 caagcagaaa atcgatttta tcatgaatat gatcaaaggc atttatccag tcaccgacga
    14641 caattattgt taagaacagc taaacagttc ttgaccgtca aaaaccggca tatctggcgg
    14701 atgactttgc gctcatatgt taagaattgg aaggtgtgaa ttcgtgcgtt cggtttgtat
    14761 agctaccttt aatggaggca gatatttaag agagcagtta gatagtattt tatctcagct
    14821 ttcagcagaa gatgaagtag tcatttctga tgatgggtca gtagatgata catgggatat
    14881 attaactgaa tacgcagaaa aagataagcg aatccagctt ttttcggggc ctcgtcaagg
    14941 attgatcgct aattttggtt atgcgatcca gcagacgaaa ggagatctaa tctttttggc
    15001 agaccaagat gatgtttggt tggagacaaa agtgaaaaag atcactgact attttgagca
    15061 gaatccggat cagctagtag tagtttctga tttaatcatt gtggacagcg agctgcaaga
    15121 gatccatgat tcgtattttt cgtttcgaaa ttccaaagaa ggatggctta ataatgtgat
    15181 aagaagtcac tatattggtg ctggtatggc tttccggtct tctttaaaac ccgatatttt
    15241 gccgatcccg tcagaagtgc cgatgcatga tatgtggatt ggtttgctgg gaggaaagaa
    15301 gactgggttc ctaagagaac cgttaactct gtaccgaaga catgatttaa acgcgagtga
    15361 gattgaaaca cattctaaat tacggcaaaa aatttcttgg cgtgttcatc tgattacggc
    15421 gttgatcaaa cgaaaatggt ttaaacgttg ataaaagatg tttaaatcct taatatttcc
    15481 atgacaaata taacaattga tgagataata acaaagtgaa atttgaaatc aaaaaggaga
    15541 gcagatatcc atgaagggaa tcattcttgc tgggggcagc ggaacacgtc tgtacccttt
    15601 aacaaaggca acatcgaaac aattgatgcc gatttatgac aaaccaatga tttattatcc
    15661 aatgtctact ctgatgttgg cgggaatcaa agaaattctg attatttcaa cgccacaaga
    15721 tacaccacgt ttcaaggaat tatttggaaa cggaaatgat ttaggactgc agatcgaata
    15781 tgcagtacaa gaaagtccag atggattggc acaagcgttt atcattggag aagaatttat
    15841 tggagatgat agtgtctgct tggtattagg ggacaatatt tactatggtg gcggtctgtc
    15901 taaaatgttg caacgagcag cttcaaaaga tacaggcgcg acagtatttg gctatcatgt
    15961 caatgatcca gaacgctttg gtgtagtaga atttgatgag aatatgcaag ctttgtcgat
    16021 tgaagaaaag cctgctcagc caaaatcaaa ttacgctgta actggccttt atttttatga
    16081 caatgaggta atttctatcg ctaaaggtat caaaccttca gaacgtggag aactagagat
    16141 tacggatgtc aataaagcat atttggataa aggaaaacta tccgtagaac ttatgggacg
    16201 cggatttgct tggcttgata caggaacaca tgaatcattg cttgaagcat ctacctttat
    16261 cgaaacaatt gaaaaacgtc agaacttaaa agtggcttgt ttggaagaaa ttgcttaccg
    16321 tatgggctac atcgataagg aacaattgct ggcccttgca cagccattga aaaaaaatca
    16381 atacggtcaa tatttattga atttggccgc tgaataagga gtccttacag atgaaagtaa
    16441 cagatacaaa attaacagat gtcaaaatcg tagaaatgga cgtctttggc gatcatcgcg
    16501 gtttcttcac agaaagttat tcaaaagcaa aatttgcaga acatggattg aaatatgact
    16561 ttgttcaaga caaccattca ctatcagctg aagctggtgt ccttcggggg cttcatttcc
    16621 aaaaaggaga agctgcacag acaaaattga ttcgggtagt cactggagca gttttagatg
    16681 tagtagtgga tatccgcaaa ggtagcccga cttatggtca atgggacgga tttatcttat
    16741 ctgaacataa tcatcgacag ttgcttgtac ctaaaggata tgcccatgga ttcgttactt
    16801 tgacaccaaa tgtgaacttc ctttataagt gtgataatta ctataatgca gaagcagatg
    16861 ggggcatcgc atttgatgat ccagatttag cgattgattg gccaattgat ccatcaagag
    16921 cgattatgtc ggaaaaagat caccgtcatc cgacattaaa agaatttgaa gcagaaaatc
    16981 catttgttta cggagaaatc taagaattaa ggagaaattt tcttatgaaa aacatcattg
    17041 ttaccggagg tgccggattc atcggctcta atttcgttca ttacgtggta aacaatcatc
    17101 cagaagtgca tgtcactgtt ttggataaac tgacttatgc aggaaacaaa gagaacttgg
    17161 ctggacttcc tagcgatcgc gtagaattgg tcgtaggaga tgttgcagat gcagaattag
    17221 tggaccgtct agtaaaagaa gcggacgcag ttgttcatta cgcggcagaa tcccataacg
    17281 ataattcatt aaaagatcct ttcccatttg tacaaacgaa tatcattggt acgtatacac
    17341 ttttagaagc ttgccgcaag tatgatgtac gctatcatca cgtatctact gacgaggttt
    17401 acggcgatct tccattacgt gaagacctgc caggacatgg ggaaggcgaa ggagaaaaat
    17461 tcactgcgga aacaccatat aatccttcaa gtccatattc ttctacaaaa gctggttcag
    17521 atctgttagt aaaagcatgg gtgcgttctt ttggcttacg tgcaaccatt tcaaactgtt
    17581 caaacaacta tggtccttat cagcatattg aaaaatttat tcctcgccaa gtaacgaata
    17641 tcttaagcgg tattcgtcca aaattatatg gcgaaggaaa gaatgttcgt gactggatcc
    17701 atacgaatga tcattcttca gcagtgtggc tgattttgac gaaaggcaga attggcgaaa
    17761 cctatctgat cggtgcagac ggtgaagaag ataataagac cgtgatggaa ttgatcttag
    17821 aaatgatggg tcaaccaaaa gatgcgtacg accatgtaaa cgaccgtgca ggacacgact
    17881 tgcgttatgc aatcgattcg acaaaattac gggaagagtt aggatggaag cctgagttta
    17941 cgaacttccg tgatgggttg gctgacacga tcaaatggta cgaagaacat gaagactggt
    18001 ggaaaaaaga aaaagaggcc gttgaagcag catatgccaa aaatggacaa taatacagag
    18061 aaaatgtcac tgtattaatg gaaaaacaca tgtgaggcag gcgctcgcct gtctcttttt
    18121 taaaataaaa atcaaggagc ggataatcat atgtttttat taactggagg aaatgggcaa
    18181 ctaggtacag aattgcgcca tttattagat gaaaaaaatc tgcaatatgt ttcaacagat
    18241 gcaaaagact tggatatcac agatgccgag aaaacaatgg cttacatcac agaattaaaa
    18301 cctgatgtta ttttccattg tgcagcttac acagcagtag ataaagcaga agaagaagca
    18361 aaagaattag atgagaagat caatgttgat ggtacaagaa atgtagcact tgcagcaaaa
    18421 gctgtgaatg ctcaattcgt ctatatcagt acagactatg ttttcgatgg aaaaaacaaa
    18481 aatgtagaat acgaagtaga cgaccaaacg aatccactaa atgaatatgg tcgtacgaaa
    18541 ttattaggcg aaaaagcagt agaagagatt ttagaagact attatatcat acgaacttct
    18601 tgggttttcg ggatctatgg acacaatttc gtcttcacga tgcaacgcct agcggaaacc
    18661 cgcgacaaac tgactgtagt aaatgaccag tttgggcgac caacttggac acgtactttg
    18721 gcagaattta tggtatatgt catcgaagaa aaagcaccat ttggtattta tcatttgtcg
    18781 aacgaaaata gctgttcttg gtatgaattc gcaaaagaaa tattgaaaga tacagatgta
    18841 gaagttgcac ctgttacgtc agaagaattt ccgcaaaaag caacacgtcc gcagtattca
    18901 gtcatgagcc tgaaaaagac agaagagtta ggatttgtca taccaacttg gcaagaagca
    18961 cttgcgcaaa tgctggaagc tgccaaaaaa atgaataagt aatttccttt tatcaaatag
    19021 aatttggagc atgatatgga aaaacaaaca agaagtgcac gacgaaaaga aaagccaaaa
    19081 gcgaaccagg cagattcgaa tttggtgctt gacctgtttc taaaactccg ctatcttatt
    19141 ggcgttttag tcatcgtggt catcgttact tttaatttaa acggaagttc acttggtgtt
    19201 tgggataaat atgtgtcgca aagagacgat gggaaaaaaa ctgatgtgat ttttggacag
    19261 aatcgggaag tgcggtcaga cgaatggctg gtgcagacac ctttttacct ctcacaagct
    19321 gaagaggact ttccgttggt gaacgaggat tattcattaa acggacaaaa catgatcatt
    19381 gcgtataatt ctcctgtaaa ggatattacg gttatcggaa aaccattcaa ctggggattc
    19441 tttttcctcg gaagagatcg aggactttcc ttttattggg cgatgaaatt agtcgtcatg
    19501 gtcttgcttg gattcgaagt actgatgata ttaacgaaga gaaaaaaagc tctatcgcta
    19561 atcggtgcat ttgcgctgac attttctcca gcagtccagt ggtggttcat gcaacatgtg
    19621 ggcgatttga ttttctttac tttgggactg atgactgctt tttatcatta tttctacaat
    19681 catgataaaa aatggctacg aacgttgatg atgcttttgg tggttatttt cggtattggg
    19741 tttattttag tgatttaccc agcccatcaa gtgatgctgg cgtacttgct gattttttat
    19801 tttgttggcc tgcttattta ctatagcaag aaagtttcat gggatctgtt ggatgtagtg
    19861 ttgattggag gggcagtttt atttattggc ggagtcatgg ttcatttctg gctaacgtca
    19921 aaagacgcat tgttagcttc tttgaatacc ttatatccag gaaaacgggt aagtactgga
    19981 ggaaagtgga cgattggcga atttttttct ttccttacaa attggaaaat tccttttgaa
    20041 gatatcaact attcgaataa ctctgaagtg gccctgttct atcacttttt tccaactgta
    20101 ttcctagcaa gtccatttgt gttatttggc aaaaaagata gcgaacaaaa gttactggga
    20161 cgtattttga tgattttttg tctgttttct atcttttgga ttaccgttgg gttgccaaaa
    20221 tggctagcag aaatcactct gctgtcttat gttcctccat taagagccat ccttactttt
    20281 agttttgcgg cttgtttatt atcgatctgg tttatcgctt atatttggag agaagatgtt
    20341 attcctattt ggtataaatt cattttgttg gcagtaaatg catggtctta tttctatgcg
    20401 attacgcatt cgaaaatgga taattatttt tcggattttg aaaccatcgc agttgctgtg
    20461 ttgggaacag tgattttagc ttttgcatta tttggctgga gacgcttgtt ttacctcgct
    20521 tttgccgcct tagttatcgt atctggcttt ttcgtcaatc cagtcgtaga aggtacagga
    20581 gcgatttttg aaaaaacact ggcaaaagaa atccaaaaaa tcgatcaaca agatcctggt
    20641 aaagtttggt tgtctgaaga tgaattatat aacttcaccc caacattggg agtgaaatcc
    20701 ttcaatacag tacgctttta tccagatata gctgcatgga agaaaatcga tccgaaagaa
    20761 gaatacgaga agtattataa tcggtatgct catacaagag cttttatcgc taaggaagat
    20821 acaaagttca ttttagatcg tccagatatg ttttcggtca cgttgaattt tgaagacgca
    20881 gaaaaattag ggatcgacta tgtgatcagt aaacgaccat taactgatta caaccaatta
    20941 tatgaagcgc agttcacgca gctatatgga ccggataaag acggttatat gatttttaaa
    21001 gtagaatatc cggattatcc agatgtacca caaacacaaa ctcaggaaaa tcagctagtc
    21061 gtacagtaat aggctagctg agaataatcc tgaaatgtta gtagaaagga gagtggagat
    21121 aattcaagca atcgtacaaa aatttgtcaa caaaatgagt gtcggtttct tgcttttgtt
    21181 actgacgcta gtcttttttg tttggacagc agggttaggt tttccagcaa ctttgtttat
    21241 atataacaat agttcattac ttatcgcttt tagtgtggct attttgctca ttttaaatgt
    21301 ttataaagca aaaggcgtcg attttcttta tctaggtgtt gcgcttgccc ttttcatttt
    21361 cttttcttac tttcgggaat taagaaatga gtctttattt ggagacttac tgtttccttt
    21421 gattatttta ttttgtttag taattaaatg gatcgagtgg acaaaatggg atcgcggtat
    21481 ttatctgatt gtcttttcgg tcttcctcgg aatcacgtta tatcgtgtat ttacagagat
    21541 ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg atatttggat
    21601 caatacgaat ataatcggaa gttctttgat gactcttgct ttattgatca gtggatttgc
    21661 cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg ttgcagcttt
    21721 tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg tttttgcgat
    21781 attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta ttgcttacac
    21841 ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg aaaaagtcaa
    21901 tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag gagaaaaatc
    21961 tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc aatttttagg
    22021 aaaccacaat
//
LOCUS       DADGHT010000045        21997 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.045, whole genome shotgun sequence.
ACCESSION   DADGHT010000045 DADGHT010000000
VERSION     DADGHT010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21997
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.045"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            202..1167
                     /locus_tag="JX887_001532"
     CDS             202..1167
                     /locus_tag="JX887_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAX1257525.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(1266..2438)
                     /locus_tag="JX887_001533"
     CDS             complement(1266..2438)
                     /locus_tag="JX887_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1257526.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(2425..3570)
                     /locus_tag="JX887_001534"
     CDS             complement(2425..3570)
                     /locus_tag="JX887_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1257527.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(3584..4508)
                     /locus_tag="JX887_001535"
                     /pseudo
     CDS             complement(3584..4508)
                     /locus_tag="JX887_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            4625..5704
                     /locus_tag="JX887_001536"
     CDS             4625..5704
                     /locus_tag="JX887_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAX1257528.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            5736..6329
                     /locus_tag="JX887_001537"
     CDS             5736..6329
                     /locus_tag="JX887_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1257529.1"
                     /translation="MTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIR
                     MPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQNLQAIIPSV
                     KSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIAD
                     ALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(6439..6666)
                     /locus_tag="JX887_001538"
     CDS             complement(6439..6666)
                     /locus_tag="JX887_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAX1257530.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(6769..9357)
                     /locus_tag="JX887_001539"
     CDS             complement(6769..9357)
                     /locus_tag="JX887_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAX1257531.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(9377..10036)
                     /locus_tag="JX887_001540"
     CDS             complement(9377..10036)
                     /locus_tag="JX887_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAX1257532.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(10085..10588)
                     /gene="trmL"
                     /locus_tag="JX887_001541"
     CDS             complement(10085..10588)
                     /gene="trmL"
                     /locus_tag="JX887_001541"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAX1257533.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(10809..11675)
                     /locus_tag="JX887_001542"
     CDS             complement(10809..11675)
                     /locus_tag="JX887_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAX1257534.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            11784..12425
                     /locus_tag="JX887_001543"
     CDS             11784..12425
                     /locus_tag="JX887_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAX1257535.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(12487..13848)
                     /gene="mgtE"
                     /locus_tag="JX887_001544"
     CDS             complement(12487..13848)
                     /gene="mgtE"
                     /locus_tag="JX887_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAX1257536.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(13866..14765)
                     /locus_tag="JX887_001545"
     CDS             complement(13866..14765)
                     /locus_tag="JX887_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAX1257537.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(14767..15564)
                     /locus_tag="JX887_001546"
     CDS             complement(14767..15564)
                     /locus_tag="JX887_001546"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAX1257538.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(15542..16246)
                     /locus_tag="JX887_001547"
     CDS             complement(15542..16246)
                     /locus_tag="JX887_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAX1257539.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            16377..16952
                     /locus_tag="JX887_001548"
     CDS             16377..16952
                     /locus_tag="JX887_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAX1257540.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            17070..17747
                     /locus_tag="JX887_001549"
     CDS             17070..17747
                     /locus_tag="JX887_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAX1257541.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(17826..19634)
                     /gene="pepF"
                     /locus_tag="JX887_001550"
     CDS             complement(17826..19634)
                     /gene="pepF"
                     /locus_tag="JX887_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAX1257542.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSDAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(19810..20808)
                     /locus_tag="JX887_001551"
     CDS             complement(19810..20808)
                     /locus_tag="JX887_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAX1257543.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(21034..21687)
                     /locus_tag="JX887_001552"
     CDS             complement(21034..21687)
                     /locus_tag="JX887_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAX1257544.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT         6492 a         4700 c         3814 g         6991 t
ORIGIN      
        1 cttttttgtg tttttcggtc ttcggacctt tttcattttc ctagacttct gctataataa
       61 ccaagaatta attttgtaac agattttttt gaaaaaacaa gtttctttca ttcaaaaaat
      121 agaaaaagct tgctaattat tggttaacca gcaaacagga gtattaaaat atcttgtttt
      181 attgaatagc aggaggaaat catgaaattc cattatcata tattgatcaa tccatcggca
      241 ggcagcggaa atggctataa agtagcagaa agaattttac cggtattaaa aaataagcat
      301 attgactata cacttcatta tagtgaatac aaaggacacg atgctgagat tgctgaaact
      361 ttggcaaaag aaacattgat tccttggata gaagaagaac agaaaacaat cgatactttc
      421 ccccttttga tcatcgtagg aggtgacggc accttacatc aggtacttga tactttctat
      481 cagatggaag tagaattccc agttgcttat attccagcag gttctggaga tgattttgct
      541 cgaggggcag gccttccaaa aaatcccaaa aaaggacttc agctgatttt agcagctcaa
      601 tcaccagaaa aagtccacat aatggcttat gaagaaaaaa taagtgaaaa aaaaggaata
      661 gctgttaata atttcggtat aggattagat gcagctatcg tccatgcgac aaatcattct
      721 tccacaaaaa agcgattgaa caaatacaac ttaggatcat tttcgtattt attctctatt
      781 ctccgtgctt tattcactca aaaaggattt ccaattctgg tagatgcagg aggaaaacaa
      841 ttaagttttt caaacgcatt tttatgtaca gcaacgaagc atcctttttt tggcggagga
      901 atcgcgattg ttccaactgc tgatgcgtct aaaccagtca ttgattttgt cgtggtcgaa
      961 cgaatcaatt tctttaaaat cttgtggctc attcttttac ttatacagaa aaaacaattg
     1021 aaatcgaaat atttccatca ctacacaaca aacagattac gtatcgtttc aacaacaccg
     1081 caacatggtc aagaagatgg agaagaaatg gaaaaacgac cttttgatat cacaataacc
     1141 acaactaaac agttgttttg gtgttaataa aagaggtttt gtcagaagct acatctggaa
     1201 caccgtttat tcggaaaaaa ggactgtgac acgacttttg tcacagtcct ttttttacta
     1261 tgcagttaat tctttgccca attgggttgc catcgatagt ttctttcttt acccaaaata
     1321 aattggatca ttgaaaacac cgcagcaaaa gcaactaaga cacaaccatt gaaccaaaaa
     1381 gattctgcaa atgtttgatt gtaactgagt gtttcactga tcaagttatt attttgaaca
     1441 aaccaatatg ttggtgtgaa tgccgctatt ttgctaacca tttctggcaa gtattctgct
     1501 ggtacaaaca ccccaccgat aaagcaactg cctgtgataa aaatatcttt gatcccaccg
     1561 ctggtttctg agttttttac caatgaagtg atacaagccg aaaagctaat gatcggcaat
     1621 aaaaacaaga aagtatttaa aatatgatac cataccgtta tatcccacga ggtgtggatc
     1681 actaacagaa ccattagaag taagaagcca ctgaacaaca gcagcgagta actaatcaaa
     1741 ctaaaggtta ctttgcgatt caagtttcgt ttggtaatgg gcgcactctg gtttcgttta
     1801 ctgatctctt tgcgattaaa tgctagattg atgacgctga aaccgctaaa aatggataga
     1861 aacaacccat aagacaagaa attaaaggtt gtgcccgtca acagcttttt catccgctga
     1921 ctatatcccg cacttagctc aacttctcca gtaaccgaga gtgccatttg tgtctgttcc
     1981 atagctgcat cgattgtttt atcttcttct tgaaacagaa tcagtgtttg caaaaaggtg
     2041 ttcacttgct gtgtaacaac tgttttagaa aaggcatctg ggcgactctg tatcttgatc
     2101 gtcggcatct ttcctacttc gacttgttcg gtaaagtctg caggcagatg taagataatg
     2161 tttacacgat taaaataaag agcatcatcg atttcttttt gtgaggttcc atccaatgta
     2221 acgactgttt ccttgtcatt caaatattta cgaaggccat cgactacagg cgactcttct
     2281 tcactaatca aggcgatttt cgcatcttgc agagaggtat tttcaacatc aatattttgc
     2341 gcaaaaaaga atgtggcaac aacagtgata attacaccta tcagtaaatt cgatttattt
     2401 gctttaagca atgtccaaat cgttttataa agcgtcataa cgcacccctc tttccatcca
     2461 agcatttcct aacgcaaaaa ggaaaataaa tccgatcaac catagaagat tggtataaaa
     2521 actagccaaa tcagtgtaga aataaagttt atacaaactt tcgctgatca agttgacgag
     2581 atttaattga ccaacaatcg gaatatgaag atcaatccaa tacttcactt gttccgaccc
     2641 catcatacca gcaaaaaagc tcatcgcaat cgtcactgaa atcaagatgc tatccttttg
     2701 caccagattc atttttggta tcaaattacc aaccaatgta cctaacaaaa tcgcacacaa
     2761 cgaccccaga gcggtaacaa tcatcaacca ttgccaacgt tcaccaaagt ctacttgata
     2821 gataaaacga aagacagcta acataatata aatctctgtc aaaacaatcg taaagcttgc
     2881 tgccaaatta gcgattgaaa ctaacgattg ctttctagga atcaaggaca agcgaatacc
     2941 atttgacgat tgatttgctt gctgatcctg tacattgcgg accccccaca tcgtcccgta
     3001 gagaatcgcc attccaatca gagtgaagaa ataaaaactt ttgaaactca tattacgacc
     3061 tgcatgaact tcttgaaaag atacttcttg ttcaaaaaca gtcatgatgg gcgcgagatc
     3121 aacgttctcc acttctgcca ctttactcga aattatacca atacgctgta aaaattgatc
     3181 catgacgttt ttcatcaacg tctgactcat tcctgcttga cccacatgga gcgaaacaga
     3241 tgaaccatca atgagataaa aaccagccaa atcatctgca tttagctttt cattcgcttc
     3301 tacttccgat agttcctgta cttcaaataa tggtttatca ttgacttcga cttgttctaa
     3361 gactgtggta aaattttccg aaagcgctgt ttgatccgct ttgattacaa ttccagtatt
     3421 aatcgtttcg agattgccac cttgatcaat ctcgccaaag gccgccataa acatcaatcc
     3481 taaaagaatt ggaaaggcca atgtccaaaa caacatggat ttatttcgca gcagtatttt
     3541 tgtgcgatat ttataaaaat gccaaaacat tatttcccct cctctagtct ctcaaatcct
     3601 tgccagtaat ctctaaaaag acatcattca aggacgcttc tttggttgct atttttccgt
     3661 aactgatctt ttcttcttgt aagattgtaa gaatcggcaa caatactgta tttagttcag
     3721 tagttgttac ttggagctga ccttttttat aagcgattcc atcagaagct attgttcgct
     3781 gacaacacgt tttctgggag taatgggatg tcgatcgtca aacgatccgc cgtccgtacc
     3841 atatctttta gagattcttt ggttccttta gcaatcacct gtccttgatc catgatcacg
     3901 atctggtcgc aaagaatttc tacttcttcc atgtaatgtg ttgtatagac aatggttgct
     3961 ccttgtcgat tcagctcctt gatactttct aaaattttat tccgactttg ggggtctaca
     4021 gctactgtcg gctcatctaa aaaaattaac cgcggcttgt gggcaatccc acatgcgatg
     4081 ttcaaccgac gtttcaagcc accactaagt tctcctggac gaaacgaaac atatttttct
     4141 aatcccacta attgaatcac ctcttcaatc aaggctttcc ttttctcttt ttcggaaaca
     4201 tataaaccgc aaaaataatc gatattttct tgcacactta gttcgtcaaa gaccgcaacg
     4261 tcttgaggaa cgaccccaat cattgccttg acagcataat tttcaggagt cattgttgtc
     4321 ccgaacaatt taatggttcc tttgtcataa tttaacaaag aaagcataca gttgatggca
     4381 gtcgatttcc cactgccgtt tggtcctaac agacctaaga cttctccttc ttgtacttgc
     4441 agatcaaaat gattcaatgc tacaaaatct ccatagcgtt tgactaattt atcaatttcg
     4501 ataatcatca tgaaaaactc cttccaaatt tcttgttgat ctgactataa taaagtgcaa
     4561 gaaaagaaac tagtgacgat tggctaaacc acacatgaca tttgtcacaa tgaaggagtc
     4621 tgctatgcat aaatctcggc tactcaacga aactagcttt ctactggtta tctcattgct
     4681 tttgctggta agtcaaggat tcgttgctat gcaagttatc tatttattga tcgccgtttt
     4741 attcactggt gtcagttatt tactgcctac aaagccaaat tggattttcc aagttattct
     4801 atttctttta tgtgcctttt tacctgatct tgtcctgttt ctgccagcga cgatgcgagt
     4861 gatcgcccct gaagaaagcc accttgatta cttgtttttg ttaggttttt tgttgatttc
     4921 gacggttggt aatcatcccc ccatcaaggt cgcctttgtc gtaattttgc tgtttttttc
     4981 cttttactta cgaaaaaaag atcaacgaac gaccgatctt gagaaaaagt acattgtctc
     5041 caaagatact cattgggaaa aacaacaaga gttatcggaa caaaataaag cattggccct
     5101 gtcacaagaa acacaattag ccttgcaaat tgtggaagaa cggaaccgaa ttgcccgaga
     5161 catccatgac aatgtcggtc atctgctgtc aagtgcgatt ttacaaattg gtgcgcttga
     5221 aatgatcaat caagaaccaa aactaaaaga accattagaa aatttaagtg ccaccgttca
     5281 cactgggatg gatcggattc gtcaaagtgt ccatgacctc catgagacat cgatctcttt
     5341 tcaacactcc ttagagtttc tgatcgctga ttttccttct tctgttacga ttgaaggaaa
     5401 cttgtttgaa ggattgaatg aaacgcagca aaactgcttc ttaatggtca tcaaagaagc
     5461 cttaaccaac agtatcaaac atagtcatgc caaaaccgtt gttttacatt ttcgaacgtt
     5521 gccggccttt tatcgcttgc aaatcacgaa tgatggcacc agcccacaaa aaaattctgc
     5581 tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa gaacaaaagg gacaagtcca
     5641 tattttccaa gaaaaccagc aatttcagtt aacgatcatt ttaccaaggg agggacacca
     5701 atgataacag tagtcattat tgagatgatc catttgtgac gaaatcgtta caaaccattt
     5761 tagaaagcac gaaagagatc cgtgtgttag gcattggtca ttgtgccaag gatgcgctag
     5821 tcttatacga aacccatcgt cccgatgttt tgctgacgga catccgcatg cctaaacaaa
     5881 cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc cttttgcttt
     5941 tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt gtcaaagggt
     6001 atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct tataatggac
     6061 aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag aataaaccga
     6121 cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc atcaaagaag
     6181 tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt gacggcactg
     6241 ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc acgcaattgg
     6301 ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa cctgaatgat
     6361 gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc gcaaaccatt
     6421 tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg gattgttcgg
     6481 cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg attcttcacg
     6541 atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca tctcatctaa
     6601 ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt cggtttcttt
     6661 agccataaag taacgccccc cttttgattt cagcttagca tatcacactg aaaaaacaaa
     6721 agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc aagcattttt
     6781 tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat ctactaactg
     6841 gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt ctacctcttc
     6901 tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt ccattacttg
     6961 gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt ttacaacccg
     7021 tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag aatcttcata
     7081 agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga tccttgattt
     7141 caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg cttgctcttc
     7201 ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca aattacgctg
     7261 aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt cactgccttg
     7321 tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt ttcttttata
     7381 agtgacctca tttgcatcaa actggataac taattcatcc actttatctt cagaatcttt
     7441 tgccaagatg atacccgtga tttctcccat atctccattg aatacattca attcgggagt
     7501 attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc aatgtacttc
     7561 cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta acgcatcgat
     7621 ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac ggaatccctt
     7681 atttttcgct ttttccacaa ttttagagat caagggttca atttgataag catcacttcg
     7741 gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc cttctttgat
     7801 ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct gattgagttc
     7861 cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag gaccgacaga
     7921 gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa tcgctttgaa
     7981 taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca aaagtccgcc
     8041 ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc ccagaagacg
     8101 atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg ctcggccagt
     8161 tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat ccaattccag
     8221 tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt tccccgtacc
     8281 tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag cttgttcttg
     8341 cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct tctgcacttc
     8401 tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg aattaccgat
     8461 cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt gttgtatctt
     8521 tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga tttcaattgg
     8581 gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg gtacgtatgt
     8641 atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc gaattcttct
     8701 cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt tgaacccgat
     8761 tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca aagactcgtt
     8821 cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac gattcagtcc
     8881 catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca tttctctttt
     8941 tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga ttttttcgat
     9001 agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga ttcctgggaa
     9061 tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt cttgctcata
     9121 tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc cataaaaacg
     9181 ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct ctttttcacg
     9241 gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat tactaggatt
     9301 ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg gctgcatcgg
     9361 aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct aaaaaatctg
     9421 tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca gtctctaaaa
     9481 tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc tcttttcctg
     9541 tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa agtgggccat
     9601 ctttatgttg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt gccgattcaa
     9661 tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc aaattcggca
     9721 gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa gtacccagcc
     9781 ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc tctttgttga
     9841 taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct ttaaaaggaa
     9901 catattttac ctttttccca aatgctttga tttcttcgta actttgtggc aaaagcggag
     9961 aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc ccatgtcggg
    10021 taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact ctataataaa
    10081 ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta gggaatcctt
    10141 gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc aatgagcgga
    10201 catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc ataaatgttt
    10261 ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca tcagcaaaat
    10321 tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta cgattaccta
    10381 aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca ttccaataat
    10441 ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc tcgattaaat
    10501 gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt gcagggatta
    10561 atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt atgttcgttt
    10621 ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg tgtcagtcac
    10681 tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca ggaacctgat
    10741 aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt ttttgcaacc
    10801 tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa taattctatg
    10861 tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg ctcttctacc
    10921 tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg tatctcaaat
    10981 tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt ggctactaca
    11041 cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg acgtagttcc
    11101 tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga gagtacacgt
    11161 tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa tgtttgatca
    11221 gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga ttgttctgta
    11281 gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat ctttttcaat
    11341 tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag cgagacttct
    11401 tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga ttggatcatt
    11461 ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg ggataaaaaa
    11521 taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat caagccatta
    11581 tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg attttctgcc
    11641 aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt ctgttttatc
    11701 ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc tagaagaaag
    11761 tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac tacacatcta
    11821 ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac ttagcggtcg
    11881 gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct ggggaaaaag
    11941 atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat aacgatatcg
    12001 aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg gatggcgtag
    12061 tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa ctattgatcg
    12121 aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt cctgaagatc
    12181 ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc ttgactcatg
    12241 gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa ttgattgcct
    12301 atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag aatgcagcac
    12361 atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg gatcttcagt
    12421 tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc aaatgttttt
    12481 gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa tcagtacact
    12541 cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat caaatcctag
    12601 acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga ttgcaaatag
    12661 catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac ctacgattag
    12721 aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt cagccaaaac
    12781 aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa cagccacagc
    12841 tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga agactgctaa
    12901 aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg tcgacatacc
    12961 taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta ctggattttc
    13021 attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag cttcatcatc
    13081 aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat cataatcggt
    13141 aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt cttggtcgtc
    13201 gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg cgtcgtcatc
    13261 attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt gattaacgac
    13321 atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt acatcgcaga
    13381 gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg cgccagccgt
    13441 ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg acatcaaact
    13501 taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag cattatctgt
    13561 atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta ggtattcttt
    13621 catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt taggcgacag
    13681 ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt gcccctgctc
    13741 atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt cccttaaatc
    13801 ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac caatctcacc
    13861 tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa aggctgcttg
    13921 aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca atgaagggct
    13981 tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag cagggcacag
    14041 ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag ctggatatca
    14101 actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc cgaacgtcct
    14161 tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg caaatcgata
    14221 tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata ttttttcaca
    14281 aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg ctttgcaaaa
    14341 agcatcaaac cagatgtatc ccgatctagt cgcgtcacca catggattac ttggttttcg
    14401 taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt tggatggtat
    14461 tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg ttcatcttca
    14521 tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc ttcagcagga
    14581 atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc tacttgatca
    14641 ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt tgagatccct
    14701 ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc ccatgtaaac
    14761 tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat gcatatgtcg
    14821 ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc ggatatttgc
    14881 ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt ccaattttat
    14941 ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa acactcgatt
    15001 attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga tcacagcacc
    15061 gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca atccatctcc
    15121 tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg tacgattggc
    15181 ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt catccaaata
    15241 actgatccga acatccagca agggataact aacactttgt tcccggttcg ttcgtaagct
    15301 gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta aatgacctgt
    15361 atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga acgccgacaa
    15421 taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat ctcgttgaat
    15481 ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct ttgcttcttt
    15541 attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct ttcttcaaaa
    15601 gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac cgctgtgctt
    15661 cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca gcttctgccg
    15721 cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta taattcagcg
    15781 aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt tccgccaaaa
    15841 ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga taagaacggt
    15901 agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc atgtcttttc
    15961 ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac atgatcctta
    16021 acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc cgtaattgtg
    16081 attttgttac aatactatcg actggcttga ctctcccagt gacaaattca atcgggacat
    16141 gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc aattctgata
    16201 cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct gatacctcta
    16261 cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt actcttgatt
    16321 tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc gatcaaatga
    16381 cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac gagatattca
    16441 tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt tatttcgata
    16501 ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc gttggtcatc
    16561 aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca acggatacct
    16621 ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt tcaggcgcag
    16681 tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa accggaaagc
    16741 ttacaacaaa acgggctgaa ttccctattg aagaaggact tttagctatt gatgaaagct
    16801 ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca tctgtgggaa
    16861 aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct gctaagaaca
    16921 agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca aggcacttga
    16981 gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta gtcactagtt
    17041 gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt gttaatcctt
    17101 taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa gaagagtacg
    17161 ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat ttgcagacaa
    17221 ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa cgtaatcact
    17281 tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt caaggaaaga
    17341 aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat gacataccat
    17401 attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg aatatgttta
    17461 aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa aaaattgctc
    17521 gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc tgcgaccgtg
    17581 attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc acagagctgt
    17641 gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat acaaatgatt
    17701 ctcagttcca ttcaagaact agccatttac acttgctttc taattaaaaa aatacgtcga
    17761 ctcccttaca agagagccga cgtatttttt tcgtttctat tcgagaaaat caaaaataga
    17821 aagccttata aacgatcgat caattcttct aattcattta gacgttgttc aaacatcgac
    17881 attgcatctt caatatatgc agcctgtgtc atatcaactc ctgctttttt cattacttcc
    17941 acaggataat cgctgttacc tgcttttagg taagccaagt agttctctag tgcctctggt
    18001 tcctggttta gtattttctt cgccagtgct gaagcagcag aaaagccagt cgagtattgg
    18061 aaaacatagt aattataata aaaatgcggt atccgtgacc attcgaattt aatttctggg
    18121 tcttcttcga ctgctggacc ataatatttt gcattcaatt taccataact atcacttagg
    18181 tattcactag tcaatggcac acctttttca tcttccgtat gcatgaaatg ctcgaattca
    18241 gcgaattgtg tctggcggaa aactgttcct ttaaacccat ccaagtaatg gttgagtaca
    18301 taagcccgta cacgagggtc tttttctgtt tccaataaat actccgttag gatattttca
    18361 ttcgttgtcg aagcaatttc tgctaaaaag atggagtagt cgccgtacac ataaggctgg
    18421 ttcgaacgag tgaaataact atgaacacta tgtcccattt cgtggacaag cgtaaatagc
    18481 tgatccagcg tatcatgcca attcaataaa atatatggat ttgtgtcata gcttcccgaa
    18541 gaataagcat cgcttcgttt ccctttattt tcgacaacat cgatccaacg ttcagagaat
    18601 gctttttcta cgatggccat gtattcttca cccattggtt tcagtgcttc taaagctttt
    18661 tcttttgctt cttcgtacgt aaaggtaatt ggagcttccc ctaagaccgg tgtataaaga
    18721 tcatacatgt gcagtttttc cacttctaat aaacgtttcc gtaattccat gtatcgatgt
    18781 aacaaaggca aatgcttgtt taccacgtct accaaagtat cgtatacact ttcaggaata
    18841 tgattattgc tcaaagacgc ttctctggca gagctgtaat tacggacttt cgctttaaaa
    18901 ttatgtcctt ttatatgtgt gcctaaagta gaagcaaatg tatttctaaa ttgttcgtaa
    18961 acactgtaca atcccttaaa tgctgcttcg cgcacccttc gatccgtgct ttctagcaac
    19021 tgaccataca cgccatgaga taattggact atttcaccat tttctccttc aatcgttgga
    19081 aaaactagat ctgcattatt caaaacagca aatgtatcac ttgaagcatc aaagatttca
    19141 cctgctccag caagaagaga ttcctgctca gcagataaga catgggctcg attatctact
    19201 atttgctgga tataatggcg atagacttcc aattttggtt cttctttgaa atattgccaa
    19261 atctggtcat ctgacaattg caatatttct ggttcaaacc aggaaacggc ttcactaact
    19321 ttcgaaaaca gactgcttgc tcttgcataa agcgcttggt aatctgtatt tccagtgtct
    19381 tgatcgtttt taaggtgcgc atatacataa atgacttcag tttggcgata aaccctcaat
    19441 acgaattcaa tcgcatttaa aaattgagaa gcgccttgat caagtgttcc tttgtgtttt
    19501 tcagattgtt ttaactcttc tgataattcc aaatatttct catcaaactc ttggtcgctt
    19561 gaaaagatct tggtcaagtc ccaagttaaa ttttcaggca attcttctcg ttttggcaac
    19621 tgctttactt ccatgaaatc cactcctttt cttcccttag ctctatctat caaaatagat
    19681 catagtctaa catccacatg tcacagcatc taacttttct actcattcat gtgtctgctt
    19741 ccatcaattt tagcataact aaatcttgtt ttacatagaa aaccgattcc tagcctattt
    19801 ttatacttac tattttttca aagaagacaa gtgtatgcat tcgttaaaaa actgctgata
    19861 gaccatctct tcatcaatca taggaaaaag ccattccctt ttatgttctt ttatttggca
    19921 aagccatgag ttgaaatcag gaactttctg gttttccaag gcttcttcgt acaacattcg
    19981 ataaagaaaa acctgttctt gtaaataaaa gaaaaaccga cttttttgat agatccacga
    20041 tgatagatgc aaaagatgtt tatgacgcaa gtagcattgt tcttgtatgg atactgtatt
    20101 cttttgcttg tgaataagtt ggcgtgtcag ccatttcttc ccatcttcac tcactttttc
    20161 tatttttttc atttggttca ttttaatttc gttactagtg aatatttctt taaggtccct
    20221 actagaaaaa gtccagcagc tactgcaaaa ggaaatatgc cctgatacag tctctgtaat
    20281 atgatgatac aaataaagct tttgtttctt gagatcagct ttccagcaat gcactcctct
    20341 ttttctatta tagtagcagc aacttttttc tatcaatgag aattgcgatt gtccaagaaa
    20401 agaattacca agtatccacc atacttggta actgttattc aaataatttt gggttctttc
    20461 aataaatctc tggtgagaca gtctagaaca ttggatttct attgctagat tcgccaacaa
    20521 aatatccggc ctttgccgca acctcggcaa ataggcttcc aaaaatactg gttctactga
    20581 ctgtcccagc caatccatga agcattcctt taactgtaag tgctcttttg attctctttc
    20641 actaaagacc gaacagttat ctgatttttg atgggcaaaa tgagcacatt ttttctttcc
    20701 ctttttcaaa atcactcttt ttcgacagcc acgacaataa tatttctttc ctttttctgc
    20761 atgtttagca aaacagcact tattatattc attcattgca agcagcattt ttctccctct
    20821 gaacttattt acgtctaaga atttatttac acgaaaaaag agggcgtgaa aaagctattc
    20881 tgcatcaagt aataagaaca gctaaacaaa aatagttccc aatatttttc gtttggttgg
    20941 gcttgttacc gcagatgcaa gcttttgaac acatttatac gaaaaaaaga ctgcgacaca
    21001 atttttgtca cagtctctta ctataatgct gatttataca aaataaaatt tcgttcgctc
    21061 gatagcatta cgcgccatca gacattgtcc atattcattc aatgtttctg gtgtacgatc
    21121 gctcttttca gcaaactcca aaattcgagc aatctgattc tctacatccg cttggttgag
    21181 attttccatc cagaagtgaa cgactaggta atagcgctct tcgaataaat acaaatcagt
    21241 ccaagcagac tctagttcga catctgttgc aagttggatc acttgttcaa aatcttcaaa
    21301 agcaaaagtt gcttgtcttt cctgttcttc tagggcgctt ccagataatt cttcctccgg
    21361 atcgctgcca ataatctgct gacgaagaaa gtcactcaca tcttctgaat caacagtaga
    21421 atcttctgat tgagaaattt cttcatccgg aagattttta ctgataaaca gttctaatcc
    21481 gtctcctttt ggcaaaactt ggaaagtgac agcttcgctt cctcggaact cctcttcgat
    21541 atcaacttct tccaaaatac tataaaagaa attttcgatt tctttgtgat tgccaagtaa
    21601 atccaaaaat gaaacgcccc gttcctctaa atcttcatga ccaattagta cacggatcgt
    21661 attttcatta atatgttcca tttccatttt gctacacctc actttgccac aatgtttaat
    21721 atagattcat tgtagcgaaa tcagcttaaa tgtaaagaaa aaaaatctcg ctgttaagcg
    21781 aatttaataa aaccagcgga tttttcaacc tttcaagcta tcttatttaa ctataacatt
    21841 tttggcagac gaatactata tagccgactt ttcagctaat tttccctctc tatttttcgt
    21901 gcaatcatca tcttctacta cctttttata catctaatca agaatacttt ttgtaaaaac
    21961 aaaaaaactt ggaaaaacta tctttgtaat agtcttt
//
LOCUS       DADGHT010000046        21498 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.046, whole genome shotgun sequence.
ACCESSION   DADGHT010000046 DADGHT010000000
VERSION     DADGHT010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.046"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            46..444
                     /locus_tag="JX887_001553"
     CDS             46..444
                     /locus_tag="JX887_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAX1257545.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            428..1123
                     /locus_tag="JX887_001554"
     CDS             428..1123
                     /locus_tag="JX887_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAX1257546.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1717..2604)
                     /locus_tag="JX887_001555"
     CDS             complement(1717..2604)
                     /locus_tag="JX887_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAX1257547.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLIDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2789..3628
                     /locus_tag="JX887_001556"
     CDS             2789..3628
                     /locus_tag="JX887_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAX1257548.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3824..4798
                     /gene="sgrA"
                     /locus_tag="JX887_001557"
     CDS             3824..4798
                     /gene="sgrA"
                     /locus_tag="JX887_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAX1257549.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5096..5452
                     /locus_tag="JX887_001558"
     CDS             5096..5452
                     /locus_tag="JX887_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257550.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5455..6612
                     /locus_tag="JX887_001559"
     CDS             5455..6612
                     /locus_tag="JX887_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257551.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6638..7078)
                     /locus_tag="JX887_001560"
     CDS             complement(6638..7078)
                     /locus_tag="JX887_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAX1257552.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7238..7744
                     /locus_tag="JX887_001561"
     CDS             7238..7744
                     /locus_tag="JX887_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAX1257553.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7912..9825
                     /locus_tag="JX887_001562"
     CDS             7912..9825
                     /locus_tag="JX887_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAX1257554.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9830..10831
                     /locus_tag="JX887_001563"
     CDS             9830..10831
                     /locus_tag="JX887_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1257555.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11033..11239)
                     /locus_tag="JX887_001564"
     CDS             complement(11033..11239)
                     /locus_tag="JX887_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAX1257556.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11885..12733)
                     /locus_tag="JX887_001565"
     CDS             complement(11885..12733)
                     /locus_tag="JX887_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAX1257557.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12897..13799
                     /gene="gnd"
                     /locus_tag="JX887_001566"
     CDS             12897..13799
                     /gene="gnd"
                     /locus_tag="JX887_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAX1257558.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13801..14802
                     /locus_tag="JX887_001567"
     CDS             13801..14802
                     /locus_tag="JX887_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAX1257559.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFNVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMCEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14799..15083
                     /locus_tag="JX887_001568"
     CDS             14799..15083
                     /locus_tag="JX887_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAX1257560.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15116..15913
                     /locus_tag="JX887_001569"
     CDS             15116..15913
                     /locus_tag="JX887_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAX1257561.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLSSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15927..16760
                     /locus_tag="JX887_001570"
     CDS             15927..16760
                     /locus_tag="JX887_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1257562.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16778..17635
                     /locus_tag="JX887_001571"
     CDS             16778..17635
                     /locus_tag="JX887_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAX1257563.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17657..18166
                     /locus_tag="JX887_001572"
     CDS             17657..18166
                     /locus_tag="JX887_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1257564.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18203..18604
                     /locus_tag="JX887_001573"
     CDS             18203..18604
                     /locus_tag="JX887_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257565.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18716..19069
                     /locus_tag="JX887_001574"
     CDS             18716..19069
                     /locus_tag="JX887_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257566.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19103..19546
                     /locus_tag="JX887_001575"
     CDS             19103..19546
                     /locus_tag="JX887_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAX1257567.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19563..20648
                     /gene="uxuA"
                     /locus_tag="JX887_001576"
     CDS             19563..20648
                     /gene="uxuA"
                     /locus_tag="JX887_001576"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAX1257568.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20641..21354
                     /locus_tag="JX887_001577"
     CDS             20641..21354
                     /locus_tag="JX887_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAX1257569.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7407 a         3296 c         4481 g         6314 t
ORIGIN      
        1 aataaaaact attagacaaa tgatatttta cgaggaggaa cagagatgac gatctttgaa
       61 acggttgtaa cagatgttgg tatagaagca gaagtattca ggaaagaaaa aataatgatt
      121 ttatttggag atgaagcacc ggaaacatta acagattatt gttataagat tgaattgaat
      181 caggtaagaa aagaaataac ttgtgatatg aagctctgtt ttgataaaca aatgtatgta
      241 atcacagcag taggagatgt tgtccaaact aatttgaatg aattaggaca tatcacgata
      301 aaatttgatg gatctcatga gccggaactt ccaggaacaa tgtatgtaga agataaggaa
      361 atgccgcatt taagaaaggg gacaatcatt aaaatcgatc aagaggatca gaatggggga
      421 aagctatatg gaaatcatgc ttgatacagc aaatacaaaa agtatttatt cttgtcaaca
      481 gtttttgaat ttaacaggcg taacaacaaa tcctacaatt ctgaaaaaag aaggagcgtc
      541 aaacttcttc tcgcatatga aagaaatcaa aaaaataatc ggacagattc ctatccatat
      601 tcagacaata ggaagaacgg aagaagaaat gatagaggat gctcgagtta tcatagaaga
      661 actgggaaaa gatacgttta tcaaggtgcc ggtgaatcaa gcaggccttc aagcgatcaa
      721 aaagttgaaa aaagaaggtt atttgattac cggtacagct atttacacag aattacaagg
      781 gtatttagct attaataatg gagcagatta tattgcacct tattataaca ggatgcaaaa
      841 tcaaggcatt gatgctatga aagtgattga ttcgttgcgg actgagatcg aacgtacgca
      901 aagaccaaca aaaatattag cagctagttt caaaaattgt gaacaagtca ctacagccat
      961 tcgatctgga gctcatgcga taacgttagg taaagagcta ctagatcaag tattagagat
     1021 gccctcgatt gataaagcag tgaggggctt ccaagaagat tgggtgcaaa ctttccaagc
     1081 agaaacgatt ggtgaactaa aaaaggtcgc tgattacttc tgaatcaatt tctccataaa
     1141 ataaacgata gccttctcga aaactcgagg aggctatctg acgattcaat attcattaat
     1201 ttaaagtttg ggtgactatt actaactatt acttatttct catttaaacg atgtattccc
     1261 taacctctaa tacatccttg taactctgaa gttacgccag ttttgaataa atttcataaa
     1321 aacaaatgaa aagtgtcgca taaaaatatc tttcgtgttt ctctagtata acagaataag
     1381 aagaacaagt ccagaaggga tatttttagt cttttttaaa ataacttttc agtcgagttt
     1441 gagtttatga tagttgtttt tgaagcgata cggcaagtga aaaaataggg aagcatgaaa
     1501 gaatctactt aatggcgcat tgattcatgt gatagaaata aaaaactttt ttaaattata
     1561 tcctcatgat tgtaacaaat ccagtgattt gttttggtac aaataaaaaa aggccccgat
     1621 gaagttgtgg caaaagtggt ttgcctcaaa aataagaagg aatttccaaa aatcacttct
     1681 caaattttgc cacatcccca attgggtcaa atttgtttat ttgaatatat tttttacata
     1741 aggatcttta atagttacat tgtctttttt catcacttta cggattgttt tatccatgaa
     1801 ttccgtatca agagtttttg cttcggtagc aattttttct agctcagatt tgtatttgtc
     1861 tttattagaa cctttatcct gtttttttac catttttact agataatagc tttgctgata
     1921 agtcgttgga tctgttacag gaatgatatc agaaacttcc ccgtttttta gtttaaatgc
     1981 tgcttttttt acttcagtag gaatctctgg attggttgaa tcaaaattca tttttccatc
     2041 agtttccttt aatgttttat tttttccata agcttgaaca agcttggaga aattttctcc
     2101 ttcatttgct tctttttttg ctttatctgc ttcttcttta gtcgaaaata gaatgatctg
     2161 tgtactaact tctggataga attctttcca agcagtgtct agatctttat ctattaattt
     2221 tacattggct ttcaaaccgt attggaaagc cagcatctgt ttaaagagtt tcttatatgt
     2281 ctcttctgtt tggccaactg cttttaattg ttccttgtag tttggaccga gttttttgat
     2341 ttgttcatta tattcttttg ttacttcctt tgaagaaatc tcttttccgt atacatcatc
     2401 aaatgctttg aagacaatca ttttttttaa tagtgtttga ttatttgatt taacttttgg
     2461 gttatcataa aaatcctgaa ctgtaagtgt tccaccttta aacgttgcaa tcgtttcatt
     2521 ggacttgcta caacctgaga atagtaaaat tgcacatgct gaaaggcaca taattagtag
     2581 ttgttttttc aaaaaatttc ccatcctttc cttattaaaa acagtctaac agaagaatta
     2641 gggagacagt ctttcatttt cgtaaggttg ctgtagatat tcttagttcg taaaaatcta
     2701 ttctctctat gatggagaac atttacatag ttttcacgag acaagaaaga aaagggttgt
     2761 taaacttaat ataaaggagg gatgaaagat gatcaggatt attcggttga ttggatctgt
     2821 tttaatagtc ttagttggtt ttgttttagg aattcttgtc aataatgcac ttgcggatat
     2881 gtttattgga aatagtgaat ggattggagc aattgccggt acggtcggac atttagctgt
     2941 ttttttacta gctttatttc ttgctagtaa ggtcgaagga aaaagaatag aagattatgg
     3001 tgtttctgtt cgaggaaaag actgggggta tttagcggga ggtctcgttg ttggaattgg
     3061 agtgtttctg cttattacta gtccattata tttgacgggg gcgtatcggt tagattcagg
     3121 aaacgcaaac attgtgccgc tgataacgag ttttatttta tttattgcag tgggggcatc
     3181 agaagagctt ttattccgtg gcttttttca gcatcagatg cttagatttg gtccgttaat
     3241 agcaatgatt ggatctgctg cattatttgc tcttttgcac ggattgaatc ctaacatgac
     3301 atttctggca gttttcaata tctttttagc aggttgcttt ttcagcgcac ttatctacag
     3361 tacaggaagt ttatttacgg ctattggtgc tcatattact tggaattgga cacaaggagc
     3421 tattttgggt ataccagtca gcggaacgca agaacaaggt tttttctcca ctctgatcca
     3481 atcgcaaaat acaataatta ctgggggaaa ctttggggct gaagcatcta tatcaactac
     3541 attattcttg ttagtcttga ttgttggttt gttactctat gcatataaaa caaagcggat
     3601 gaagaaatac actgctgttt atcaataaaa gatgaagaaa gcaaggctga tatcggtctt
     3661 gcttttttaa gtctgtcatt gattaaacga aaaagtaaac aaattcaagc gaatacacga
     3721 catcttttgt tagattttca caactgactg tcgtgttctc atcattttca ttttatataa
     3781 ttcctttatc aaatagaagg taattatatg gagagtgata gaaatgaaga aaacagcgac
     3841 cgtattattt gttattcttg ggctgagtat aattgcagca atgattggaa tcagtacttc
     3901 tgcaaatgaa cgggcaaatg agaatctttc atttactgtg aaaactgatc ggattgttta
     3961 tgacatgaca caacaagtca ttactattcc agtcaaacca aacaaaagcg tgaatgctag
     4021 tgatgtacat gctgttctaa catatggttg ggatggtaat ggaagttcag aaaaagttat
     4081 tggggaagtt tatttaaaag acgtacaatg gaccgctggt attgagtata caataatgat
     4141 ttctgcagaa ctatcgattg atgagatcaa gagtaaagat aaagttgatt tgattgtttt
     4201 ttatgatgga cagatgacga tcacggagaa tttgaaacca agcagttgga cagttgttgg
     4261 accgccaagc agtacggata gcacaagtag tgaaagcagt acagaaaaca cgagcggtga
     4321 aagcagtaca gagagtacga gcagtgaaag tagcacagaa aacacgagca gcgaaagcag
     4381 tacggagagt acgagtagtg aaagtagcac aggaagcacg agcagcgaaa gcagtacgga
     4441 gagtacgagt agtgaaagta gcacaggaag catgagtagt gagagtagca caggaagcac
     4501 gagcagcgaa agcagcacag gaaaagtaaa taatgaactt gatttggtac ctatcatacc
     4561 aactaaggaa caaaagagaa atgcagggag caacctaaaa agtgtgctaa aacagcctga
     4621 ttttgtttct cgtggaattg atcatcaaga aaaagcgaaa gaaacagata atagaaaaag
     4681 cgatttacca gaaactggta gtagaacctt gaacaagcta attacatgga tgggtgtgtt
     4741 actcattttg attgtaggag caagctattt tcgttctctc ttccatcgag tgaaataaag
     4801 aataaaagca acagatctaa aattgaataa aacgatagat ttttgagtga atatttcatt
     4861 cgagagtgct gtattgcctg gcgaagttgt agctttgcca gatctatttt tgtttactaa
     4921 catatttgag aaacaggaaa taacaggaac acaaatggaa aataagagca agaataattg
     4981 acaatgcaca ctgcgcatgg tagtatctct gaaaaatcag taacgaatct atttgtacgt
     5041 tattcatgta gctgtcggaa taagtctaaa taatagataa aaaggagtat gtactttgtt
     5101 tgaagaattt attgatatca atgaaaggca agtatatcaa tttttgaact attgttatga
     5161 aagagacgag aaattatatg tggtgaagga tatcgcttta gatctaaact acaccctggc
     5221 taagatgaat tcggtgattc aacaagcaga atcgttttgc gaaaggtatc cagaatataa
     5281 attatctttt ctttcagaaa acaagatgat aaaagtcgag ttttcttctc agtttttact
     5341 gagtaaagtt tattctatac ttttagaggg aacgattggt tatattttac tggattcact
     5401 ttacaaaggt acttatcaat ccttagaaaa tcttagtcaa aaaattatat aagtttgcgt
     5461 acgattcaaa gaaaattaag agaacttaat actattttga aaaactatca tttatcttgc
     5521 agcttgaaaa aaggtaatcc gatagaagga gaagaatacc gtatccgata cttttttcac
     5581 ttgatgtatt ggcagtcatt cgacgaaaat cattctgata tattatcaag tataaaaaat
     5641 aaacgtcaac tattagaaaa atttgcgaaa catgcgccat atacgcgtag tatagataga
     5701 aagaaatgga tcagcctact aagaatttcg ttgcaacgaa tgaaacaagg ccactcgatt
     5761 acgtatgtcc cagaagagat gaacaaattt gtgcatccat tgataacaaa agaagagttt
     5821 acgcattaca tactagagcc tttttttgaa gcaaacttct ggtcgatgaa tcacatcact
     5881 ccaacagagc aagcttacct ttattttatg tttggtgtaa tgaacaccta tttggaagaa
     5941 gatttgttgg atactccaga taaagtacaa gaaagttggg gctggattga atcgtctatt
     6001 gtagaaaatt ttgaaaaaaa cttcaagatt tgttttacaa cttcagaaaa aaattatcta
     6061 tatgtcaatt tggcaatgat ccatttgtat tcaagggttt ttgggacaaa aaagaaggtg
     6121 gatgcttttg gaaaatcagc agaagacaga gattttcagc atatatttcc agtgatgtat
     6181 ccaatcatgc aacagttttt tagtggggta gctcgcagaa ttccagagct taatacttat
     6241 tatgaaaaga acagacggtt gatttttcaa tactgtatgt tagtcaggga tatttttata
     6301 aaacacgaac aacctgtcat attctatatt caatcaaagt atggtaaaac acaggaatta
     6361 tgggcaaaga aaaggatatt atctatgact gaacgcccaa taaaatatag tgcatccgct
     6421 gatcagttac ctgatattgt cattagcgat tatcctatcg acaaaaaggc atatgatcaa
     6481 acgaatacac agatatttta ctggaatgga caacctacaa aaaatgattg ggcgcgtctg
     6541 aaagctgaaa tcataaaaat caggaatgag aaaaatagat ccatattgga aaaattggat
     6601 ttcgttaatt aagaaaagca gattgtttat gccaaaatta agacattgca aaaagattat
     6661 tttctttaaa atcgacaaga tgaccagaaa gcaagagttc gttgagctct tgctttcttt
     6721 tagttttaga aaggaacatc ctgattttat cttcgctaaa tccagtcaaa agttttgcag
     6781 attggtcgta gataatcggt tttttcaata aagaagggga tgtacgaatc tcaatatata
     6841 gttcactcaa actgagttca tctattctgt gaacaagatt tttataacta atagaatgag
     6901 tagagagcat ttcggtcacg ccgttgtttg tcaattttag taagtggata aattcatttt
     6961 tggttagtgg ttgacgaatt aagttctgtt cgataaacgg tatatcatgg acgataagcc
     7021 aacgttttgc gcgtcttgaa gacgagcagc cagaacctgt atacaattta atcatcatac
     7081 attcctccaa tagctaagta tttatgaaat aataacatga agaaatagtc gaaaagtgcc
     7141 atttagaggt gtaaaataag aaaatgttgt cacgtataat ggaactagct agataagaaa
     7201 tactattaaa tcaagaaaaa agaaagaagg cacaagtatg tcaaacacag ccgacgcaat
     7261 agtagtgatc gatttacaaa aaggggtatg ttttgattct tcgccgatac acgaattaga
     7321 aacagtgaca gcattagtga ataaaagaat caaaacatac gaaacgattg ggaaaccagt
     7381 tattttcgtt caacacgaag atgctcaatt agtgccacaa acaaaaccat gggagctatt
     7441 gtcggaatta tctattcctg agcacagtta ttttgtgaga aaaacccatg cgaattcatt
     7501 ttataagact aatttgagtg ttttattaac tgaattggac tgtcattcga tcgaattatg
     7561 tggggcacaa gcagagtatt gtatagatac gactgtgaag tttgctcatg gattaggata
     7621 ccagcttatg atgtgtagag gagcaacgac aacttatgat aatcctttta tgaaagcaaa
     7681 ggaaacaatc gctttttacg agaaaatttg ggataaacga tttctgacat ttttggagca
     7741 ataagttgtt tcttcgttta aaaaaagcag aatggatact ggtttatcca ttctgcttta
     7801 ttacgtaaaa tgagaaaata atcctgttct atttttatgg gataaaccat ttattttttg
     7861 tataaaaaat gtttgcgttt acatataatt ctcctagaaa cataaaaagg agtgaatagc
     7921 ttgagaacaa aacaagtatt aaagggagcg ttggtcatct tatttgctgt aagtacaagc
     7981 gtcccgcaat ggacagtata tggagagagc atttcttccg aatcggaatc tcgggaggta
     8041 gaaaccacag aaactactga tgctggaaat gaaacgaaat cgagtacttc acaaacagaa
     8101 acaaatactg aaacaacggt tgagacatct gttactagca cagatcaaga aacgaccgct
     8161 accacagata accaacaaac agaagaagca acagctacaa aaatgtcaaa cgacgaatcc
     8221 tcttctgcta aagtaagtga caaagagaat gggacagaaa atgatgatat cggtaaaggt
     8281 gaaaatttca atggtaaaga atatttgaat tacttcggta aacagatgac agaaatactt
     8341 aatggaccaa cagaagacat caagtcaaaa ttaatagagt tattagtcac tgagcttgct
     8401 gttaatgatt atggtgtaga taaagagatt atcaaacatc tgattgctac ttatctattg
     8461 tacgatatcg cttttgcaaa aaacagtgtg ttgatgtcga tgcttggagg tacagatgat
     8521 gggacaacgc ctacagaaaa cacaggcttc tatccaaata caaaacaact tcatcaaact
     8581 gtactaaaca aacaagatgg caaaatgatg gatgtatatg catattatgt cgatcaaggt
     8641 tcagataaaa cagtcatgat ccatggcgga tttcgaggga attggaataa cgggatcgtt
     8701 acagaagaat acaatgattt ttataaggcc gggtataatt tattatttgt tgattccaga
     8761 gcgactggta atagcggagg cgattatgtg acctatggac aatatgagtc agatgacgtc
     8821 ctttactgga taaatcaaga agttcgagag cggccatctc aaaagatttt actttatggt
     8881 ggttcgatgg gagcagctac gatgatgtct gtattagcga aagatattcc tgtcaatgtc
     8941 aaaggaatta ttgaaaattg cggatttgca tcaattgatg aacaactacg ttttacgtac
     9001 agccagacag tagcccccgc actaccggat gccataaaaa atcagttaga catcattggg
     9061 gatcaagagc atgaagattt atttatgggc cttttgaaac aatactattt tgatcaggag
     9121 atgcatttgg atacaaaagc tgctctacct acgattggaa tgtcagattc attgcctaaa
     9181 ttgattatcc atggaacagc agatgatgta gtacctgtgt ctaacgcgca aaaattatat
     9241 gagttatcag gagggtataa agatctttta ttagtagaag gagcagggca tggaaaggca
     9301 caggaagttg accatgctgc ctacacgaaa catgtaacgg actttttgaa agtagtgttc
     9361 catgatcaga taaacgtaaa gtatgtggat gaaaacaata aaagtctact caaagaccag
     9421 gacgaaatcc agctttacgg agcttatgga gaaaattata tgacagagca aaagacattc
     9481 gaaggatacg aattagcaaa tgttgaagga ccgactgaag ggatttttaa tgagacgata
     9541 ccaactatta ttttctatta caaaaaaatc ccagtagctc caccaaaaaa gcaagatccg
     9601 acagagaatg cagacaataa gggaaagaat gaacctcgag aggatcaatc aagtgatgat
     9661 acgcaaccga ttcagatgac agtgaaagta caaaaaaaga cagatgcaaa aaaaagaatg
     9721 ttgccgaaaa ctggagaaaa gaaacattcg cttctcattt attcaggtgg atttttatct
     9781 gttagcacga ttatcacatg gatttggcga agaaagagag ggtaaatgaa tgaaatggtt
     9841 caagcgaata gtgattgcag taccagttat catcgtagtt attttagtca ctgtattttt
     9901 gattaatcaa atcacaccaa agccgattag cttgcttgtt agaaaacaat ttgacacaag
     9961 tgaaaaagaa caagtatatg cccgaccaga tgatttccag caaaaaatcg aacaaatcga
    10021 tataaaaaaa gaaatatcct atccttcaaa gtacaaaaat aataatatgg atatctacac
    10081 accgaaagtg gaaaagaaaa aattaccgat tcttttctgg atgcatggag gcgcatatgt
    10141 aggaggggat aaaaatgatt gtcgtgatta tttggaatat ctatgttcag acacgcagca
    10201 aatcatcgta aatatagatt atgaacgatc accggaagca aaacatccta caccagttat
    10261 ccaattgaac gaagccattc aagcagctaa aaaagagata aaagatcaag cagattggtc
    10321 gaatatttcg attggtggaa attcggcagg tgcacaaatt agtggagaat atttgttagc
    10381 acttcaaaat gaagaaatta aaaaagctga tcatcttgat ccgactttgg agaacaagca
    10441 gattacgaag tttatttctt tgtctggtct gttggatcct tctgcactta ctcaagtaag
    10501 tgataaaatc tctagctttc tttatgaaaa atgtggatgg gcttactttg ataataagga
    10561 ctttgaacaa tcagagaagg tcaaaagttt agccttggtc agacatgcgg atcgttggac
    10621 gcaaaacaca ttcttaacgg atggaaatac aaatacgttt acgaaacaaa tggaagaagt
    10681 aacttctgta tttgagaaag cgggggtgaa agtcacaaaa gtagattatg cggagaaaaa
    10741 tgctgttttg aaccatgaat atcagtttga tttcagcaat aaacaagcgc aagaaacata
    10801 tcaaaagtta gtaatgtttt tcaaggagta aagtcttatg atgcaaaaga ggttgtaatc
    10861 tgtcacttag ctccaagtca caaggagcaa tttcaataaa caagcttttc atggtttatg
    10921 aatattgtaa cttgtgactg aggagttaga gatggcaagg ggcacctttt attcgaaatt
    10981 tgggaatatc acacgattat tgtcacgatc tcttttacgt aaattttata agtcagattt
    11041 gttgttttga tcgtttaaaa aaagcaacaa atccgaagcc tgcggaggca agaagggaca
    11101 aaaagccgag tggtaagcaa aagaatgctg gttccactaa tattccgttg ttattgatat
    11161 aaggctggga acaaagatga atagcaaata aaatcaatgc actagcgaaa aaaagcaaag
    11221 aaatatggat agctttcata agcagcacct ccttttttat aattgtatga taaatagatt
    11281 aagaatctat aaatgtgaca agtttgttag gatgtgaata aaatgatcat ctagcgaact
    11341 tgaaacaaag atggctaatg ataagcaatt aatgattcag caatcagata ggtacaaagt
    11401 ttaccatcat acgtctagac caataataga aaatatggga atataataga aaagatttag
    11461 gataccccca aaagaatttc cccaaaaatt cgatgtatcc taaacttttt tattttacat
    11521 aacaatcata tcaactgtga aataaaatta caaatgataa cctaaaatga ggccaaaagc
    11581 cagtgttatc aaggaaatac ttaattcacc aaaatttttt ttaatttttt agaaaataag
    11641 aaacaaaaat aataaaaaaa agaaaagata aattttttac tactgtatac taactttgtt
    11701 atcgcatcta acaagtaact cgaataatac caatacaacc ttctccaaag atgcgatgac
    11761 atacgttcta acccaccgac tattgatgtt ctgtaccacc cttgcagaac caaaaaagcc
    11821 actaccaaat atttggtagt ggcttttttt gttttatgga tttttcgctt tttctgttat
    11881 ggtgctattc tttgatttca gaaatagtat gtcgaacttt agcgatagaa cgacgtgatt
    11941 ctttttcgtt gtaaaacatc aaaatcacat atagagagtc caaaatgctt agttgagaaa
    12001 tacgggaagc taaagcttca gatcggaatt ctgtttcttc agaaatagaa ataaaaacga
    12061 catcgccaag tttagcaagg gaagaattag cttggctagt aataacgatt gtttttgctc
    12121 cagtttttct tacggtttca gcaatatgga ttgtttcttt tgattgccct gtgtgagaaa
    12181 tcaaaacagc acagtctttt tccgtcaata aagaagcttc catcaattga atatggtaat
    12241 ccgtgctgtg agaagttgcg ataggggaac gcaaaaattt atgataagcg tcagttgcta
    12301 caatctctga accgccaaca ccgaaaaaat agacacgttt agattcattg ataatagtag
    12361 ccgctttttt tagatccttt tgttgtaaca acttttttgt gtcatttaaa gttgaaatac
    12421 tagactcgaa caccttttgc gccatagtga gctcagtatc tgttttctga atattttcgt
    12481 ggatagaaat agcagataga tcattttctt ggatcaacat ggccatttta aaatctttaa
    12541 atccattata accaagtttt tttgtaaatt gaaaaaaagt agagtcagca atgcccagtt
    12601 cacttgctaa attgctaata ggactatgac ttactttgct tggattttct aaaatataat
    12661 cggcgatagc ctgttctttt gggctgaagt cgttgtacat tgttttgatt tgtagtctta
    12721 tggagacgct catgagaatt cctcattttc ataataagat tatcattttt tccgttctca
    12781 ttaatgttaa agatacaagg agagtaggaa aaaatcaaac aaaaaatatt tttgtaaaat
    12841 ctatttacaa aaaaattttt ttgtataatg agggtataag aaatggaggc gctatcatgg
    12901 aaattggtgt aattggtttg ggaaaaatgg gattgaattt agctttaaac ttaaaagagc
    12961 accatcacaa agtacaagga ctcgacattt caagtacagc tgttagtcag gcaagagaaa
    13021 atgacattcc tgcttatcaa gagatctctg aatttctagc tacttttgag cagaaaaaaa
    13081 tcatctggtt aatgcttcct gctggagaga taaccgaaaa catgttaaga aaactttttc
    13141 caaaactcgg accaggagac attattattg aaggcggaaa ctcttattat aaagattcaa
    13201 tccgtcgagc agaagagttt cagaaaaatg aaatcggtta cttggattgt gggacttctg
    13261 gaggaatcga aggagcacga catcaagcct gcttaatgat tggaggagat aaagaaactt
    13321 ttctatccgt ggaacaatta ttcaaagatg tagcaattga aagaggatat ctgtatgctg
    13381 gtgcatccgg aagcggacac ttcttgaaaa tgatccataa tggaatcgaa tatggaatga
    13441 tgcaagcaat cggtgaagga ttccaacttg tacaaaaaag tgagtatgct tttgacttgg
    13501 aacaagtcgc acgtgtttgg aatcatggtt cggtgattcg cggctggctg atggaaatca
    13561 tggaagatca gttaaacgaa catcccaatt taagtaatta tcggggaatc gtttctgcat
    13621 caggtgaagc aaaatggacg gttgaaacag cgctagaaat ggctgttcca gttccagtaa
    13681 ttgcaactag tttgttcatg aggaatcttt cacaggaaga agatagtttt tcagcaaaag
    13741 tagtttcagc actaagaaat gggtttggcg gacatgaaat agttgaaaag ggtgagtaaa
    13801 atgccagatt atcatatagc aatcgttaat tccagcagtt tcggaagagt ctttccacac
    13861 cacttggaaa gattaaagtc agttggagac gttcatttct ttaatgttga tcaagagatt
    13921 ccaggaaaag aactagcgga gttacttaaa ggattcaata tcattattgc aagtgttacg
    13981 ccattttttc gacgagattt ttttgaaaac aaagatgaac tgctattgat ttcccgacat
    14041 ggtattggtt acaacaatat tgatttaaaa gcagcaaaag aacaccagac aatcgtatct
    14101 atcatacctg ctttagttga acgaaatgct gtagcagaaa ataatataac taatttgttg
    14161 tccatgcttc gacgcacgac acaagcacaa gcaagagtca aggacgatcg atgggaagat
    14221 cgggcggagt tcgtcggtag gacgctgttt aacaaaacag ttggtgtgat tggtgcagga
    14281 aataccggaa gcggagtaat cgaaattttg cgtaacggtt ttcgctgtga tgttctagct
    14341 tatgatcctt acaaatcaga tttatacatc gaaagctttg gtgcaaaaaa agtagaactt
    14401 caagaattac tggaacaatc agatatcatt tgtttatgtg cgaatttgac agaagagaac
    14461 tatcacatga tttctgataa agaagtcgat cagatgaaag aaaatgttta tctatctaat
    14521 agtgcaagag gcgctctagt tgatgaagaa gcgatgatta atggtctgaa aagcggaaag
    14581 atcgcaggat atgccacaga tgttttagaa gaagaaccgg gacgtcaaga tcatccgtat
    14641 ttagcgtttg aacaagtagt gattacgcca catatatcgg cctacacaag ggaatgttta
    14701 gaagcaatgt gtgaaaaatg tgtcagagat gtcgaacaga tcagtcagca ccttcttcct
    14761 gaacgttctg tccagacaaa gagcaactat ataaaaggat gatgaagaaa atggtgaacg
    14821 gtttaaaagt gaaaacaggc cctcaatttt atttatatga agaaggtggt atttcaaaag
    14881 tttctgatct cttgaaatca tacggcgcga aaagagtact ggtcacccac ggaacggtat
    14941 catgggaaaa ggcgctacct aaattagtat ttttgaatga cgaaacgatt caattttttt
    15001 atcatcgtta ttctggagaa tgtagttatg ctgaagccag acgaatagct acaatcatca
    15061 aaaaaatgaa atcgatttcg tagttggcgt tggcggagga aaactgaccg atctagtggg
    15121 ttatagtgcc aatcttgcaa gaatcgattt cggagtcatc cctactttag ctagtaattg
    15181 tgctccatgg acacctcttg ctgtcatgta taaggagaat ggacaagcag aagggaaaac
    15241 agaacacttt tacagacaag ctgctttttt tataacagat ccccaattag tgattgattc
    15301 ccctgttcca tatttcattg ccgggttagc agatacacta gcaaaatggt atgaatctga
    15361 gctcatctta gaacaagatt ttttgcaaga tgaatcattt ttgaagctag cacaagatac
    15421 tgcgaagatc tgcaaagaag agattttgaa tcattctgct aaagcaatcc aagatatggc
    15481 acaaagaaaa ctgtcatcgg agttcaaaca gctttcagag attatctttg ctgttgctgg
    15541 tttagttgga ggattaggag ataaatacgc aagaaatgtg gcagcacatg ctatgcatga
    15601 cgctatcagt aaatatattc cggaaagcca tcgttttcta catggagaaa aagtagcgta
    15661 tgggattttc tatcaactgg cactagaagg tcgctgggaa aaaatagacg agttatatcc
    15721 tttgtatcgg gaattagaac tgccggtttc tctagaacaa atgggattat ttccgaaaga
    15781 taaacagata atagataaaa tggctgaatt tattgattcg aaagagaaag tgcatttgat
    15841 tcctatagag gtaacacaga aatcactgat acagtcaatg atggaactgg aaggttatat
    15901 cagaaagatc tgaaggagga ggacacatgg aaacattaag tgtagtacaa agtttgttga
    15961 ttgctttatg ggtagccgcg gttatgtccc gctggttagg tggaggagcc acgttgacct
    16021 tacgtttttc tcctttgatg actggattag tcgtcgggtt gatcatgggg gaagttgcac
    16081 aagcgatgat tgttacagcc gctttgcaaa tgatttatat gggggttttt tctccaggag
    16141 gatcaatgcc agctgaacca tctattgcag cagctatcgc agtaccagtc gcattattag
    16201 gggatctgtc gccagaagca gcgattgccg ttgcggtgcc agtcggattg ctcggaagtt
    16261 acttgtatca gtttcgtttt ttcatcaata cttttttagg taaatataca gacaaagctg
    16321 tagaagattt gaatacaaaa gctatggccc gatcaattat tctttatcca acggttgcct
    16381 catttttatt attcgttccg cttgttttca ttgctttata tttaggggcg ccattgatcg
    16441 ctgatgtaat caaagcttta gagggaacag tcgttatcca cattcttgaa gtagtaggtg
    16501 gagggttagc ggcaatcggt atcgcgacaa ctgtatacgt tatcggtcga aaagattatc
    16561 tggtcttttt cttccttgct tattttatga gtgttgtttt gaaatcttta gatattacga
    16621 tggttactta tgccattttt gggattatta tcgctttgat ctttgtccag tcgcaaaaag
    16681 ggaaacaagt acagcctgcc acaagcaata acaattcagc atcttttgat gacgaagatg
    16741 actatgatga cggattttaa tttaggagga atgggaaatg gctgaaataa tggataatca
    16801 aacaggtgct cctgaagaaa tcacgaaaaa agatgtaaca aaagcctatc tgagatggca
    16861 ttttgcaaac gaaattcctc actcttttga acgttacttg gcgccatcac tactatacgg
    16921 aatgatgcca atcttgaaaa aactttataa agatgaagac tctttaaaag cagcatataa
    16981 acggcagtta ctgttcttca acactcaatt aagctggggt ggcggtgtga ttactggcct
    17041 aatgtcttct atggaacagc aaagagcaga agaagagtat gaagaaaaag agatcttgat
    17101 gcaggatgac ttgatgtata acacgaaagc gggattgatg ggggcactag caggaatcgg
    17161 agatgcaatc gattcaggaa ccgtccaata tatttttatc gcaatcgcgg taccttgggc
    17221 acaacaggga agtcctttag gcgcactttt tccttttatc tgctttgggt tgtatcaggt
    17281 tttactaggg gtatttttcg caagacaagc tttcactatg ggccgtaatg ctacaggcct
    17341 aaagcaaaac actggtgttc agacagcgat tgaaatgcta tcagttttag ggttgtttat
    17401 gatgggggtg cttgcgggaa actatgtaaa agtagaatct tcattgaaat ttgcgatatc
    17461 cggacgtgag tttgttatcc aggaaattct tgatcaaatc gtgccaggga tattaccttt
    17521 agctgtcgta atgggtgtgt acttgttcta tacgaaaaaa ggattgaaag tcacacaagc
    17581 attattatgg ctgactggaa tattaattgt gctagcagga atcggtattt tataaaaaga
    17641 agggaacgtg aataagatgg gtgtagtcaa tttagcgcgt gtggatgagc gtttgatcca
    17701 tgggcaagta atggtaacgt tatctcaaaa aagtggagtg aattccattt ttgttgtaga
    17761 cgaagttgta gcaaaagata aatttatgag agatctttac aaaaatgcag gaagccgtac
    17821 aggacaaaaa acaattgtca ttacaccaga gaaagctaaa ttctattggg atgaatatca
    17881 atttaaagaa tacaattgta ttttgatcgc aaaaacagtc caaacgattt acgacttagt
    17941 aaaacacgga atccccatgg aagaattgaa tattggaggg attgctcaaa aaaatcctga
    18001 tacagatctt ttagtgacga aatctgttta tttaaataaa tcagatgctg aaaaattgaa
    18061 agaaatgaat gaacaatatg gcgtaaagaa tatttatttt caagccactc catctgcacc
    18121 taaaacagga ttaaaagatg tattgaacaa gtttgatttg tcataaacaa atgcttagaa
    18181 aaaagataaa gagggcgaaa aaatgaagaa gaacgagctg tttcgtgatt gggaatttcg
    18241 ttatcgctat atttaccgta agcgccgtac aaaaaagagt aaacagcgtt ttctttcagc
    18301 attagtatca gatatttaca gtatgagaac agatgtgaca gtcattgctt acgatacgct
    18361 agcctaccga tcaaaaaata tttatgttgg agatatcgaa aaagcagaga aagttatctg
    18421 tacttattac gatacacccg ttcatgcatt aggaagttat ttcatgtttg attggaaaga
    18481 ccaaaggaaa aaaacaatct actctatatt attgtccttc attttgttgt tcagtttagg
    18541 ttggtgggga atgatgatat ataacaaaaa tcctcatcac gtattcgatc tgctatccgt
    18601 ataaacaggt atcactgtac tagcatttgg gagctacttt ttcttattgg gaaaagcagc
    18661 tcgcggatgg cctagcagac aaacttttat tcgaaatact tcatccatat taacgatgct
    18721 agaaatgatc cgtacgattg atgatccgag tgtagcgtat gcgtttgttg atgaaggctg
    18781 ttatggagaa aagggcttag acagcgtgag atcgggtatg aaaaaagagg ctattctttt
    18841 ttatctagac tctgttgggg cagatacacc gctacagttt tcgggaaatt atttttcaaa
    18901 taaagaacag tggctgaaac aagttgataa gttgaaagaa aaaaacgtca attatatttt
    18961 tagtgcaaga aaaaagcaag cgcagttctt ctatttgacc aaaacagatt tacgagggaa
    19021 aacatttaat tggcaaaatg ccaatcagat tattgctctt tttcgataag taaaaagtgc
    19081 aaaacaagga gtgagaagac taatgttgga aatcatgatc gttacacatg gtaagttgag
    19141 cgaaggactg aaagatgcgg cggaagtaat tgtcgggaca tcgagccata ttgaaacaat
    19201 gtgcttagag tctggggagg acatccaaac attcggagag aaggtcaaag aaaaattaac
    19261 tatgatcaac acagcagaac ccatgctagt atttgttgat ctaattagcg caagtccgta
    19321 caatcaagcg ctcttggcag tcaatgaact gactgaagaa aagaaagcag ccacttatgt
    19381 catagggggc gtgaatctgc caatgttgtt agaagcaatc aatcatcaga tgcttcacac
    19441 accgatagaa gaagcggtgg aacaaattgt caaacaagga aaagataatt taactgtttg
    19501 gcatgcttca gcggaagaaa aaaaattaga tgaggacgat ttttagaagg aaggctgaaa
    19561 agatgaagtg gggatttaga tggtatggtg aaaaagggga ttcgatccca ttaaaatatg
    19621 ttcgccaaat accgggaata aatgggataa ttggaacttt gctgactaaa atgcctggag
    19681 atgtttggga gatttcagaa attgaggagt tgaaagcatc tgttgagagc caaggactgg
    19741 aactgcttgg aattgaaagt gtagcgatcc acgatgcaat caaggcaggg acagatgaac
    19801 gagattacta tattgataac tatatacgaa caatcaaaaa cttgtctcga tgtggggttc
    19861 gattgatttg ttatagcttc aaaccaattt ttggatgggc gaaaactgat ttgtttaatg
    19921 aaaacaacga tggaagctat tctcttttat acgatcagaa aatcgtcgat cagatggagc
    19981 caggagaaat gtatcaattg atacacagcc agtcaaaggg attcaaattg ccgggttggg
    20041 aagaagaacg gttgaaaaaa ttcgctcagc tggaaaaact gtatgaagga atgaccgaag
    20101 aagaattatt tgaaaatctg acttattttt tagaaaaagt gattccagtg tgcgaaaaag
    20161 cagatgtaaa aatggctatc catccagatg atccgccatg ggaacttttt ggttttccta
    20221 gagtgacgaa aaatcttggc gacttgaaga aaattctaaa tgcagtagat tctccatata
    20281 atggactaac gctgtgcaca ggatctttag gggcaaatcc ggaaaacgat ttagttgaaa
    20341 tcatccatga ggtaggttcg cgcatccatt ttgtccactt cagaaacgtg gagtttttag
    20401 gagaaagaaa gttcaaagaa acggcacatc cctctacaga aggctccctt gatatgtatc
    20461 atattatgaa agcgttggtg caagaagggt tcgacggtcc tatacgccct gatcatggta
    20521 gaaccgtgtg gggtgaagtg gctatgcctg gatatggcct gtatgatcgt gcaatgggac
    20581 tcacttacat gcaaggtcta tatgaggcga taagtaagga aaaaccactg ggagagcatt
    20641 atgaataaaa tcaagctctt catctttgat atggatggcc ttttattaga aactggacgt
    20701 ttagcttatc gtgcttatgt aaaatcagca caaaagtatg attatgaaat gcgtaaggaa
    20761 gtctattatt tactaactgg ccaaacagaa atggcgataa gagaacaaat gggcattttg
    20821 tacggagaag atgttccata tatcaaatgg cgagaagcaa tcaatcaata taaagaaaaa
    20881 atcgtgaaag aagataagag agtatatacg aaaaaaggag cagaagaaat tttatctttt
    20941 gcaaaagaaa gaggaatcca tacaatcgtg gcttcgtcta atacacgggt aaaagtagaa
    21001 atgtatttaa aaatggaaaa tctatatgcc ttgtttgatc aaatcatttc aggggatgat
    21061 gtaaaaaaag gaaagccgga accagagatc tttttgaaag cttgttcaaa aatgaatatt
    21121 cctccaagtg aagcacttgt atttgaagac tcgattgcag ggatcgaagc agcaaggcga
    21181 gcgggcattt tgtcttttct catcaaagat catttgatag ggttgcccga tcataatggg
    21241 aagcataagt tgaaagtaga tgtaagttta tatgaatcca ataaagcaga ctatgaattt
    21301 tatgacctgc atcaagcaaa acgattttta gaaagtaaag ggttgtatct ctaataaaga
    21361 ggactatttt ctagtcctct ttatttattg tcctgcacga ctgagggaac agatgaaaaa
    21421 gaagtaattt tttattttga agtatctacc ttatttgtag tgaacaattt agaacaaaca
    21481 caaaacgcat ctactgtt
//
LOCUS       DADGHT010000047        21308 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.047, whole genome shotgun sequence.
ACCESSION   DADGHT010000047 DADGHT010000000
VERSION     DADGHT010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.047"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            68..808
                     /locus_tag="JX887_001578"
     CDS             68..808
                     /locus_tag="JX887_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAX1257570.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1232..1402)
                     /locus_tag="JX887_001579"
     CDS             complement(1232..1402)
                     /locus_tag="JX887_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1257571.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1596..1775)
                     /locus_tag="JX887_001580"
     CDS             complement(1596..1775)
                     /locus_tag="JX887_001580"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257572.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            2162..3274
                     /locus_tag="JX887_001581"
     CDS             2162..3274
                     /locus_tag="JX887_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAX1257573.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3352..3645)
                     /locus_tag="JX887_001582"
     CDS             complement(3352..3645)
                     /locus_tag="JX887_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAX1257574.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3813..4127
                     /locus_tag="JX887_001583"
     CDS             3813..4127
                     /locus_tag="JX887_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAX1257575.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4148..6127
                     /locus_tag="JX887_001584"
     CDS             4148..6127
                     /locus_tag="JX887_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAX1257576.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6140..6466
                     /locus_tag="JX887_001585"
     CDS             6140..6466
                     /locus_tag="JX887_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAX1257577.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6482..7000
                     /locus_tag="JX887_001586"
     CDS             6482..7000
                     /locus_tag="JX887_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257578.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7000..8352
                     /gene="celB"
                     /locus_tag="JX887_001587"
     CDS             7000..8352
                     /gene="celB"
                     /locus_tag="JX887_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAX1257579.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8436..9941)
                     /locus_tag="JX887_001588"
     CDS             complement(8436..9941)
                     /locus_tag="JX887_001588"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAX1257580.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10033..10623)
                     /locus_tag="JX887_001589"
     CDS             complement(10033..10623)
                     /locus_tag="JX887_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAX1257581.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10802..12448
                     /locus_tag="JX887_001590"
     CDS             10802..12448
                     /locus_tag="JX887_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAX1257582.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12497..13216
                     /locus_tag="JX887_001591"
     CDS             12497..13216
                     /locus_tag="JX887_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAX1257583.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13695..14642
                     /locus_tag="JX887_001592"
     CDS             13695..14642
                     /locus_tag="JX887_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1257584.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14654..15574
                     /locus_tag="JX887_001593"
     CDS             14654..15574
                     /locus_tag="JX887_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1257585.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15615..17072
                     /locus_tag="JX887_001594"
     CDS             15615..17072
                     /locus_tag="JX887_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1257586.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17417..18031
                     /locus_tag="JX887_001595"
     CDS             17417..18031
                     /locus_tag="JX887_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAX1257587.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18024..19748
                     /locus_tag="JX887_001596"
     CDS             18024..19748
                     /locus_tag="JX887_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1257588.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19745..21196
                     /locus_tag="JX887_001597"
     CDS             19745..21196
                     /locus_tag="JX887_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1257589.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
BASE COUNT         6867 a         3609 c         4317 g         6515 t
ORIGIN      
        1 ggggtatgaa ttagatgcga caccgatcga gtttgagatc gaaagaagtc agacagcggt
       61 ggtagaattg acgaaagcaa accgacttac accaggcggt gtcgtgttga caaagatcga
      121 tgaccaaagc ggggaagtcc tgcaaggagc tgtttttgag ttacaagatg ccaatggaac
      181 cgttctgcag tcaggtctaa ccacaggagc agatggaaaa ctggcgattg acggcttagc
      241 accaggagtg tatcagctgg tagaaaccca agcgccaacg gggtatgaat tggatgcgac
      301 accaatcgag tttgagatcg aaagaagtca gacagcggtg gtagaattga cgaaagaaaa
      361 tcgacttaca ccaggcggtg tcgtgttgac aaagatcgat gaccaaagcg gagaagtcct
      421 gcaaggagct gtttttgagt tacaagatgc caatggaacc gttctgcagt caggtctaac
      481 cacaggagca gatggaaaac tggcgataga tggcttagca ccaggagcat atcagctggt
      541 agaaactcaa gcgccaacgg ggtatgaatt ggatgcgaca ccagtaactt tcaagatcga
      601 aaaagaacaa gaagtggcga tctttttaac aaaagagaat agaaaagttg ctgatagctc
      661 agatataaga ggaaacaatc caacaagcag tggaaataag catcttccaa aaactggaga
      721 aaccatcatt agccagttta tattgtcaat attgggtgtg ctacttgttt tcatcagtat
      781 aaaatttaga aagaaacgaa atatatgagc taaaataaaa aattgaataa gcatagtttt
      841 taaaatcaac tagtacccat caattgaatg gaaactaccg attttagaag gggtatacaa
      901 acaaatatta gtatcggagt agagaaggtt gaacccaacc agtaaataag taaagacaat
      961 tttgtgctgc gttgagaagt gaaaaataaa cctttgtagt aatactagtt aataaaaaat
     1021 atacaaaaac actgcgaaaa tcattcttga gtttcgcagt gttttttgcc taatgactca
     1081 agtttattgg gtaatacttt gattttcttt ctacaaataa tcagcgatca gttgtaattt
     1141 tttctctagt tttaatggct ctttgtcaat aaggagaaaa acaagtcggg tcttttgtct
     1201 cggaaagctt caaccaactc gtgaataaag gttacgcctc cttgaaaggc gtggaaaaac
     1261 caagtaatcg atcaatcacc aatttcgcat ttggtagaac atgtttggtg agctgaaagt
     1321 aggtggcgtt catgtctgta actaagaatt ctatttcttt aggattagtg cagctaagga
     1381 aatagtttgt taatcgagga attttttgtg taggtaaatt ttctcgatta atttttctgt
     1441 ctcgccatcc gcggaaataa aactcagttt atcctcaacg gaaacgtgag aacgaaattc
     1501 acaaccctca acactcaaga cagaattctt ttggaagact ttggtaaata gcttctcaac
     1561 tctttcaatg tgcgaataac ggttgtcaaa gatacctaac aacttttcga aataaaaaat
     1621 aacgacactt tttcagtcag taaagaagtg attttatgtc tgacatgatt tgaaatcgag
     1681 tgccttggac ggataaaata actttgagcg ttccaatggc ttcgacagtt tttacaggta
     1741 tagcgctgct tttttaggcg tataaccatt ggcatatgat tatattattc aaagtggaca
     1801 atggtttcct tcttcttgtt tttcaccacc attaatttcc tatttccatc taccacagca
     1861 gaaccacaat ttctacagac acatggagca gggaagagaa ctgcagcaac gatcaatgtt
     1921 tttttcttct gtaaggtttc gtaagagacc tctgtaatca tcaaattttt gtctattgat
     1981 ctcagaattt ttttgataga accattcata aagcatatcg ttctctcagt tgtttatttt
     2041 gtggtgattt aatcatacaa gaaaacgata tgttttttta taaaaacatg aataggaaaa
     2101 atagttgaca agaaaatgac aacgccatat gatgttccat agtatttaca acctgtcata
     2161 gatgactgta aaaaataaaa gtaaaaagaa aggacgacaa caggtggatt tttatcagtc
     2221 tctacaacta gatccgttta ttttaaaaca aaaaatacga gaagcagctt ctaaaaaaga
     2281 aaagtgcatg tatatttgtt cattgttttt acgatcatta ttcatcgtat tgtttgccat
     2341 ttgttttatc attataatta caacattatt tgaatcgaag cataaaccat acgctgtggt
     2401 tttattctgt atgttgatga gtattcgttt tgttgacttt ggttataaga tttcccattc
     2461 gatcataggt ttagcaatcg tcatgttctc actattagta gcaccgtatg tccagctgat
     2521 caaatggtca gttatgggca tgttgattca ttttatttta ctaagcagca tattaatggc
     2581 aaccgctagt gatcccaaaa tggggaatgc ttctttgtac ggcttttcat atctctttat
     2641 tgtttattcg ttacctaaag attcgttgaa caagaatttc tttacacaaa caagtagctt
     2701 attatttttg tttttttgtt ggttttcagt tctcctttac agaaaacatc gagaaaagaa
     2761 caaagacaaa agcttgttta aagagatttt tttgaaaggc atgtattcgc aggaaaaaat
     2821 ttggatgctc atctatgcat ttggcattag tcttttgatc gttgcaggag agtatgtccc
     2881 ttttcagcga ttgatgtggg cagggtttgc attttcttct attgtatcta gctatggatt
     2941 gatgtcgatt ggtttcaaag aacgagcagt agaccgaatc attggctcat tgattggatg
     3001 tgttttattt attggtatca gccaatttat tccttttaac tgggtcggta tattaggtgg
     3061 tctagcttta ggtgtttgtt ctacctatag atataaaaca gtttttaatt cttttggtgc
     3121 tttggcaatc actgccagtt tattcggggt tccaggagca gtaacgatcc gcatttttga
     3181 gaatatcctt ggggtatgtt taggaatcat gtatattggg gtgactgaaa tacttatccg
     3241 aaaaataaga gaaaaacacg gtttgaatca ttagatgaga tcgaataaaa aataaggaaa
     3301 aagtgaagat acacatggat gataaattgc tatcattcca tgtgtatctt tttacggtaa
     3361 atcagtgaaa cgttcgactt tcatttttaa tttatacttt ttacggagtt cgtttatttg
     3421 agccatcatt tcggatttgt gatgcttttc gattgcttct tcatctttcc aacggtcgat
     3481 cagtaaaaga gattctggat cttctagtgg aaagtaatag tcatatttct cgtttccttc
     3541 ttctgcacga atcgctttga caatgtttct ttcgaccatt tcttctgcaa attttctggc
     3601 ttgtccattt gtacttgtat acaaaatatt cactgtgata ctcactaaat cccctcctga
     3661 aaaaattcta tcactagtat atcacggtgc cagaaattat tattcaagat atgatacaca
     3721 ttttttccgc aatgctacgg aaatatatat tttgaataga aaacgcttac aagatatgct
     3781 tggtttataa aaataaaagg agtgattgat ttatgaaaaa agcattgatt atttgtgcgg
     3841 caggaatgtc atcctcgatg atggcctcaa agacaacgga tttctttaag caaaaaagag
     3901 aagaggtact cgtagatgca gtttcagcta cagaaggcga taatatgatt aagaatagtg
     3961 attttgattt atttctgatc agcccgcaaa cgacgatgtt tttggataaa ttcaaaaaat
     4021 taggagaatc tgttggaaag cctgttgtta gtatcccttt ccaagcgtat gtcccaatcc
     4081 ctacaggcat ccagaagtta gcagaggtga tcgaagagaa catatgatgg aataggagtg
     4141 gatgataatg aaacagaagg aaaaattgct gttgagatat ttgattgatc acaagaagga
     4201 gtatgtcacc agtcaacgtt tagcttctga attgttatta tctgatcgga caatccgtaa
     4261 ttacttgcag cggatcaaag agttagtaga aaaaaacgga ggtaagatca ttgctaaacc
     4321 aggttatggc taccaactgc atattttaca aagactgaca tttgacttgt ttttgagtcg
     4381 gcaagaaata gtacctggat atgctagaga accgcaagga ttttatgagt ccgaagatcg
     4441 acaaaagtat atattgaacc aattgctttt ggaagatgcc attcttttta tggatgattt
     4501 ggcagaagag ctttatatca gtcgttccag tttgacaaag gacatgcaag aaatcaagga
     4561 gcgattgatt ccatattcac taaaaatcgt ttctaagcat ggtcaaggga catggatcga
     4621 aggggaagaa agaaatcgac ggcattttat catggatact ttttttggaa accattatgg
     4681 aaattcattg aaagaatatt tagggcaaag ccgttttttc ccagacatca gttttgaaga
     4741 gctagtcatt atcattctcg atgaaacaag agaagctaag ttaaaagttt cggattttat
     4801 catacagaat ctgactttac acttggcttt ggggatcaaa cggctccgag aagggtttga
     4861 aatcaaggaa ttaggcatcg aacaagaagt ttctaagcga gtagagtatc aagtggcgca
     4921 gcggatcgtt caacgtattg aggtaatcgc aggtgtatcg tttcccgaag aagaaattgc
     4981 ttatttgaca ttacatctca tggctaagtc gaatcacaaa gaaaatcaaa atgatcagga
     5041 actatcaaag gaattagcga aagttctgaa aagattgtct caggaatttc atttttcatt
     5101 agtagaggat ctccagcttt tcaatggact actcgatcat ttgtcaccga tgatgattcg
     5161 attgagccga ggtattcgca ttgagaaccc attgactgag gagataaaga aagaaaatcc
     5221 caaagtcttt gacgcagtaa aaaggcattt cagcaacatg ccggctttga aaaactatac
     5281 catcaatgaa gatgaatggg cctatttggc tttgcatctc atggcggcat tggaaaaaga
     5341 aagagctgcg cataaactac atgcattgat tatctgtgca acgggttacg gcagtgccca
     5401 actattaaag aatcgcgtag tcagtgaatt cggtaaaaat attacagtgg taagtgtaaa
     5461 aggctattat gagatcaatg aaacaacttt aaaaggaatc gacctgatta tttcttctat
     5521 tgatctttcg acaatgtttt tcaaaattcc agttttacat gtcagtattt ttttgaatga
     5581 agatgatgtt cgtaaaatac gaaaggtagt tggagaatct ataccctatc attcctcaga
     5641 tagaccgata ccagcatttt ctctacagca aaaaaagcag atttacaccg aacagttgtc
     5701 tgaaaaattt ttcaagactt atacgtacga accgaaaaag gaagaaattc ttcatgattt
     5761 gctgcaaaag ctgagcataa atgaagaaga aggatatata agagaaatgc gaaagcagat
     5821 ccagcaacgt gaaaatatgg gacaaatcat attcagtgat acagtggcag tcccacatcc
     5881 cgctgttcca gttggaatcg aaacaaaggt agccgttgca ttgattcctt ctgggatgca
     5941 gtgggatcaa tatcaagaaa ttcattttgt ttttttagtt tcgccttctt atgtcgaaaa
     6001 tgaaggaatt acggtcgtga ctaaagcaat cgttaggtta gttgaccagc taaaagtaca
     6061 gcaggaaatc ttagctgaac ctatttttga gaatttcagc agtaaattta tcaaactgat
     6121 cgaataagga ggaaaacaga tggctgaaaa aataaacagt gaaacactac aagtgacttc
     6181 ttttgatatc attttccata gcggaaatgc acggacactg atacatgaag catttcgctc
     6241 gatgcgtaaa gagatgtttg aagaagtaga agagaagttg cgacaagcaa atgaagagat
     6301 tcttcatgcg catcagtcac aaactcaact tctgaaagaa tatgccagcg ggacaaaaat
     6361 agaaatggaa attatcatgg tccatgcaca agatcatctg atgacgacga tgacattatt
     6421 ggaagttgca caggaaatga attatttgta tcaaaaaaat aaatagaaag gaaggatcat
     6481 tgtgcaggat acagtaaaaa ggaaaatcga attagaaaaa aagcaactta gtttgaaaaa
     6541 catgtatttc aatcgttatc taatcgtacg ttacctgact gcctttttct ttttcatgaa
     6601 catgcaatgg atgattctgc ttctatcagc taaaagttta ggaagtagtt taccgatgat
     6661 tctgatttta gctattttgc ctgcagtagg agaacaagta aagctttatc gaaaacacca
     6721 aacgaacgtt ccatggacaa agtggtattt tttgttccag agtgtcttta atttattagt
     6781 gattccagtg ttgtttacct caggatttac attcttgtat ccttttatgg caaataacaa
     6841 tggaggacag ttatttgttt tcattcttgt tgtaagcggt atttttgcca gtgcatttat
     6901 acagtatcgt ttaaagaaaa tttcactcaa ccaagaccaa cagtatatcc gtattaaaca
     6961 atatgaaaaa gcgttatatt taggaaagga gaataactaa tgtttgattt tttgcagaaa
     7021 tacctgatgg gacctatggg gaaaattgcg caacttaaaa tcgttcgggc tgtcatggca
     7081 gcggggatgg cttctattcc tttcacgatt gtaggctcga tgtttttggt tttaaatatt
     7141 ttgccattac cgttcccatt tttagaagga ttttttaatg caactttttt caaagttagt
     7201 gacttgtaca tgatcgtcaa tacaatgacg atggggattt tatctattta ctttgccatt
     7261 gtgtttgctt atgaattaac gtcaattgaa cgagatgaac aaaaattaaa tgttaatccg
     7321 ctcacggggg cattactatc tgtttttgca ttctttatgt gtatccctga attgatcatg
     7381 actgatggta aaatcagctt gattgcttct atcaatgaga cagaaactgt agtaaatggt
     7441 attaggatgg gctcttttgt cgaacgttta ggaacttcag gaatctttac agctattatt
     7501 atgtcgatta ttgcggtcga attgtattgt atgtgtgtca agagaaattg ggtcataaaa
     7561 atgccagatg ttgttccgcc aggagtttct cgttctttca ctgctctgat cccaacattt
     7621 gtcattgcgt ttgtggtgat gatcatcaat ggattattag ttgcactagg aacggatatc
     7681 ttcaaaatga ttgctatccc atttgggttt gttacgcagt tgacgaatac atggcttggt
     7741 gtcatggtga tttatttctt gatccatgca ttgtggatcg tagggatcca tggagcgaat
     7801 atcatcactt ctttcttgac cccgatcgta ttagctaata tggcagctaa cgcacaaggc
     7861 gcaaattatc cgttggcagg agaattcaac aattcttatg taaccgttgg tggatcaggt
     7921 gcgactttag gattgatcat ctttattgca ttcctcgcga aatctgatca gctgaaagtg
     7981 ttaggaaaag cctcacttgt accaggatta ttcaatatca atgaaccaat cattttcggg
     8041 atgccaatcg tctacaatcc ctatttagcg gttccgtttt tcttagctcc gatggcttct
     8101 gctacactcg cttattttgc cattcggctg gaaatcgtca aaccgatgct tgcacagatg
     8161 ccgtggcctt caccagtcgg gatcggagca tttgttggta gtggtggtga ttggaaagct
     8221 gctgtgttag cagtcatttg tgcaatcatc gcattcatta tctggttccc atttatcaaa
     8281 ttctatgata ataaattatt aaatgaagaa agagaaaagg cagcagaatt agctagtgaa
     8341 aagttaaaat gatttctaag aaaaaaggaa ctgtgacaaa aaatcacagt cccttttttt
     8401 cttagaaatg ggaaaccact agtatataaa taccattatt cttcaatcaa ccgcttcacg
     8461 attgcataat ccccttcata aggttcatct acaccattga ttttttgata gggatccacg
     8521 ccttttcccg caataacgac tgaatcttgc ggagcgcttt ctgctaaagc gcgtcgaatc
     8581 gcttcaggac gatccatttc ataatgaacg atcaaatctg gattagtaat tgcttcattg
     8641 atttcttccg cgattttttt cggatcttca aatgctgggt catctgccgt caaaaaggcg
     8701 atgtcagctg tttctgatag cacttttcca aaatcatgtc gacgggagat tgctttgttt
     8761 cctgggctgc ctaatacaac aattacacgg ccatctggat gttcattttt ggcaaatttc
     8821 agcaatgttt tcaagcttag ataattatgt gcatagtcca catagacatg cgctccattg
     8881 gattggatca attgatccat tcggcctggt acacgagctt cttttaatcc gtcttgtgca
     8941 tcttgactgg aggcacctgt tagtgctgcg gcaatgatcg cactggctgc attttcttgg
     9001 ttgaatcctc cagccagcaa aatatcataa gcagtatcgc agatagctaa gcgatcttca
     9061 tgagaagata aagtaaaacc gtgagtacct ttatctgaac ggatcacttg ataattgctt
     9121 tcttccgaac gaccataagt gatcgttgga atctggaata gatcggctgt ttccctaagt
     9181 aaatcaaaat agtcactttc atgatttaaa acaactgttt ttgaattcaa gatcaattgt
     9241 cgcttgcaat agaaatagtc atcaaatgtc ggatgttcga tcggactgat atggtcaggc
     9301 gagatattca agaagattcc gacatctaaa gtcaagccgt atacgcgttg tgttttgtaa
     9361 gcttgtgaag aaacttccat cactagatga gtcataccat tttcaactgc ttctgacatc
     9421 atacgatata aatctaatga ctcaggcgtt gtcaaatggg atttgaaata tgttttgcca
     9481 tctaacgttg tattcatagt agaaagcaat gctgtttttt tatttgttgt gtgatccaag
     9541 attgcttttg taaagtacgc agcagttgtt ttaccttttg ttccagtgaa tccgatcact
     9601 ttcaatttat tttgcggata gtcgtaaaaa gccatagcaa gaagcgccat tgctttacgg
     9661 atatccgtta cgatgattcc tactgctgaa ttttcgtatg gttgttctga tacataatat
     9721 tgaataccct gttcgattgc tgaatccaaa tattcttctt tgaaattcat tcctttacag
     9781 aaaaacaaag tagaagcatc agcttttctt gaatcataac ttaactgaag aaattcagct
     9841 ttttctggta catcaagatg ccagcctctt gttgaaacaa attcttttaa tagattttct
     9901 tttaatagta aatgacggat gtcttctaaa gagaagctca ttgattgatc cctcgcttta
     9961 ttcaatttct tggtttatta tagcacactc tttttaatat atcgtttgtt tccgctatga
    10021 caaaatccag ctttattcaa attttcttga cacaggggac aagcggatga gtattttcat
    10081 aaacaatgaa ctgactgtaa tagataggag aacgaatagt gtctccaaca atccaaaaac
    10141 ataataattc aaaaagacga taagactatt ggtaagtaaa agtccttgcg gcattggaag
    10201 ccgaaaaaat ttgtggaaaa taatcggcgg tatcgttata ccgccatttg aggccccgac
    10261 tgtgtacaat gtgtaaaccc caagactgaa caaaagactt cctgaaatca gtgaaaagaa
    10321 atgtgaggag atcatttcca cttttggaac aatctctaaa acaacaggaa aaagcagact
    10381 tcccgctaca gtcttaaaaa atactgattt tcctaatagg acagcggcta gaagcagcat
    10441 cataagattg atgctccaaa cagtaactga gcgttggata gaaaaggccg tttcaactaa
    10501 atgtccgatg gcgcccactc cggcggaagc tatatcgtga gggagcaaga accaattcaa
    10561 tccaactgtg ataaagaaaa gacctaaaaa tataacgggt agttttttta tttcttgtgt
    10621 cattgatatc tcctataaat gttagccata aaaggctgta tatttcttta ctttaccaaa
    10681 aaaacgaaac cgaattcaaa aaaacaattg ttcttataaa agttatataa aatcgattgc
    10741 cagtttctgt tttaccaatt aaaatgatag taatgttttg tagaaagttg gaatctgacc
    10801 gatggataat caaagaaaac cagcattaga tcaattaaca ccgcaagaaa aaatggcacg
    10861 aggctctgct tggatgaccg ccagtaatat catttcaaga ttgctaggcg ctgtctatat
    10921 cattccctgg tatgcttgga tgggcgaaaa tgctaaggct gccaatggat tattcaatat
    10981 gggatacaat atatatgcat tgtttctact gatctctaca gcaggaatac ctgctgcgat
    11041 tgcaaaacaa actgcacgct ataattcatt gaatgaatat ggcacttcac gacgattatt
    11101 tatccgtgca ttacagatga tgggcgggtt aggcctgttg tttgctttgt tcatgtacat
    11161 cgcctctcct tggctagctc atgcttctgg tggcggagaa gaactgattc caacgatgcg
    11221 ttctttgagt atcgctgtat tggtttttcc ttgtatgagt gtgatacgag ggtatttgca
    11281 aggcaatcaa gaaatgatgc cttatgcgct gtcgcagatt gtagaacagg tggcacgtat
    11341 tttttatatg ctattggcta cattcatcat catgaaagtc atggatggtg actatgtgac
    11401 ggcggtcacg caatcaactt tcgcggcatt tatcggtatg ctagcaagta ttcttgtcct
    11461 tttgtatttt ttgaagaaac atcaagcgta tacatcggcg tttattcact acagcgaaaa
    11521 caaaataaat attgcaacga aggaattgtt gttagatacc gttaaagaag cgattccgtt
    11581 tattattgtg ggttcagggg taacgatctt caaattagtc gatcagttca cttttatgaa
    11641 gatcatgtct gcatccaccg agtattccaa tgcacagtta ctggatcttt tttcgatttt
    11701 tagtgccaat ccagataagt tgacgatggt agttattgca ttggcaacat cgatcgcgtc
    11761 tactgggtta ccgttgatta cagaagctgt tacgttgaaa gatcgagtag gtctggcaaa
    11821 attgacaagc ggaaatttac agttgttttc attttttatg tttccggcga catttggtgt
    11881 tatgttactt gcctatccgc taaatacatt attttataca ccggattctc taggaagtaa
    11941 tgtactgatc caagcaagtt ttgtaggact cttcctagga ctatatatgc tagtttccaa
    12001 catgctgcaa ggaatgtttg aaaacaaggc ggcaattaat tatttggtta ttgggtttct
    12061 agtgaaactc cttcttcaat acccagccat tcgtttattt gaagtatacg gccctttatt
    12121 ggcgacaatg atcggatttg ctgtgtcttg taccttgatc ttaaagagaa tccatgaagt
    12181 agcccgcttt aaaccaagtt ttgtctggcg caggacattg ctgatcttta ttcttacctt
    12241 gattatgctt ttggcttcgt ggatcacaaa gatgattttt ggtgcttttt taaacgaaga
    12301 tagcaaattc cagtctctat tgttgattct tgtagtagca ggtatagggg ctttagtgta
    12361 tggttattta gctttgaaaa tccgcttggc agaaagacta ctaggaccag gaatagcgcg
    12421 tttacgacat aaattaaaaa taaaataagt gaatcagaag agctagattg atgctctttt
    12481 gaaatggggg aaacgcatgc gtttagataa gtttttagca gatatgggac ttggcagccg
    12541 caaagaagtc aaaggattaa tcaaaaaagg aacgatcgaa gtcaatggac aagtggtgaa
    12601 aagcgataaa gcgcaagtaa atgaattcga agatgcggtt acttatttag gagaaatcat
    12661 tacgtatcaa aaagattttt actacatttt gcataaacct gcaggagtca tttctgctac
    12721 tcaggataat catgatcaaa ccgtaatcga tttattggaa gaccaggatt atcgggaaga
    12781 tctttttcca gtcggccgat tagataaaga cacagagggc ctcttgattt taacgaatga
    12841 cggggtgttt gcccatcagt tactatcacc taaaaaacat gtggagaaag aatatctagc
    12901 tgaggttagc ggtataatga cagaagaaga tatccgttta tttgcagaag gactgattat
    12961 tgatggcgat gagcagacat tgccggcaaa actccaaatt gatcaagtag atcaagagac
    13021 agaaacttca attatccgtc tgattttgca tgaaggaaag tttcaccaag ttaagcgaat
    13081 ggtcaaagca gtaggaaaag aagtcttata tttaaaaaga atccgtatgg gaaaattttg
    13141 gctgcctaaa gatttgaata aagggcaata tcgacccatg accaaagaag agctagaaca
    13201 agtgagagaa aaataattga atggatagct aaaagaataa gcagagtagt tgtagcgcca
    13261 tctgaaaagc agacttgtcc gtctgacttt cggatggctt ttttgtgaaa tttcggctta
    13321 tttccgtaga agctacttct ggaacaccgt ttgttcggaa taagggactg tgacaagact
    13381 tttgttacag tccccattgt tccttgtgac tcagagttag atagtaagga cacgatctcc
    13441 ctaatactca ggccaaaacg ctgaattcac aacctctgat aaacggtgtt caatcagctg
    13501 accctcggta ttagctcaaa aaacggcaaa atatgaggaa ctattttccc gtttttttct
    13561 ctaatactca ggccaaaacg ctgatttcac aacctctcct atactttgtt tcattttccc
    13621 tatactttgt ttatttattc tcattattga aagcgctata attacgttgc gaatgaatcg
    13681 aaaggggttt ttagatgaaa aaacgaaagg ggttcaatca tttttttatg aatctatggc
    13741 gttataaagc acttgtcctg atggctgtac cgggtatgct ttggatgatt tttttctttt
    13801 acatacctgt aatggcgaat gtcgtagcat tcaaaaattt tcatatttca gcagatgggt
    13861 tcttggctag cttgagggaa agtccttggg tgggttggga aaatttcaaa tttttatttt
    13921 cttcggatca agcatttctc atcactaaaa atacaatttt atataatgta gcatttatcc
    13981 ttttgaatct gctgatctca gtcgtatttg caatcattat gagcgagttg agaaataaac
    14041 gactcgttaa agtttatcaa acgatgtcct tactacctta ttttctatct tgggtcatta
    14101 tcagttactt tgtttacgct tttttaagtc ctgacaaagg aatattcaat cagtggatca
    14161 ctggacatgg aggagaagct gtcaattggt ataatgaacc gaaatattgg ccgtttatct
    14221 tggtgttcat tggtacatgg aaagggattg gttataacag cattatttac tttgcatctg
    14281 ttatgggaat cgatccgact tattatgaag ctgctatggt tgatggagct agcaaatggc
    14341 agcagatcaa acatgtgacg ataccacaac ttattccact aatgacgatt ttaacgattt
    14401 tagccgtagg aaacattttc cgagctgatt ttggcctgtt ttataacatt cctaggaatt
    14461 ccggtgcatt atatgatgtg actcaagttt tggatacgta tatctacaat ggcctgacat
    14521 ccacaggaga ttttggtatg acggctgctg caggacttta ccaatcagtt gtcggctttg
    14581 tcttgttgat gatcacaaat acgatcgccc gacgttttga tagcgattct gcattattct
    14641 aaggaggaaa aaaatgaaaa aaaagaaagt ggagagagtc caagtccgct ctttcaataa
    14701 gacggctaat tttttctcta atataatgat tgcactcttt gctatttcct gtattttgcc
    14761 atttatattt gttatcgcca tctcttttac cgatgagtcc atattgtcga ctcacgggta
    14821 cagtttttgg ccagaaaagt tcagtatatt tggttatacg tacttgttcg accagatgca
    14881 ggataaaatt ttccaagcgc ttttcgtcac tgtacttgtt actgttttag gtacactgat
    14941 caatagcacg gctacttctt tatatgctta tgcgatttca cggtcaaact ttccattccg
    15001 tcgttttttt accgtttttt gtttgattac gatgttgttc tcaccaggga tggtggccaa
    15061 ttatcttgtt atgacaaatc ttcttcagtt aaaagatacg atttgggcat tgatcttgcc
    15121 aatggctgtc agtcccttca atattattgt gatgcgcaca ttctttaaac gttcggtctc
    15181 tgattcgatt attgaatcgg cacggatcga tggagctagc gaactgcgaa tatttgttca
    15241 gatcgtttta ccgttagctg ttccaggtat tgcgacaatc agtttatttg ccgcattggg
    15301 ttactggaat gactggttca atgctttact ctacatccaa gatgataagc tagttccact
    15361 acagtatctt ttgatgaaaa tccaaagtaa tattcaatat ctgacacaaa attcaggagc
    15421 aggaagccaa ttgacaggcg gattagcctc agttccagga gaatctgcca gaatggcgat
    15481 cgtagtcatc tcgacgttgc ctattgcgat cagctatcca tttttccaga agcattttgt
    15541 caaaggtcta acaatcggcg gagtaaaaga ataaagaaac aaaaatataa atcataaaat
    15601 taggaggaag aaaaatgaag ttatggaaga aactagcctt tacaggtgtt tcagcgttgt
    15661 tgttgggaac attagcagca tgcggaggtt ctggttctaa agaccaggca gaagctagca
    15721 attcggacac tttgcagatg tatcaaatcg gagataaacc agataatttc gatcaattga
    15781 tggaagtagc aaacaaacga atcgaaaaag agatcggtgt aaaagtcaat atcaattaca
    15841 ttggctgggg cgattacgaa aagaaaatga acgtcatcat ttcttccggg gaaaattatg
    15901 atatcgcctt tgcgaacaac tatgtttcca atgcccaaaa aggagccttt gctgatttga
    15961 ctgaattagc gcctaagtac gctgaaaaag cttataatga tttagatgaa gcatatatta
    16021 aaggaaatct ggtcaatgga aaattatatg ctttcccagt caatggaaat gtctttgctc
    16081 aacaagtact tacttttaac aaagctttac tagataaata cgatctttca attgatggaa
    16141 tccaatctta cgctgatgca gaaaaagtct tgaaggaatt ccatgaaaaa gaaccaaaca
    16201 cggcagcttt tgccattgga caaggcttca aagtccaagg gaactttgat tatcctttag
    16261 ggaatacgtt accatttgct attgatctgg atggagatga ttcgaaaatc atcaaccaat
    16321 acgataatga aacgtatatc ggactgttac gtacaatgca tagctggtac aaacaaggac
    16381 tcattccaag tgacgctgca acgagcaata aggattatcc actagaagga aatacttggc
    16441 taatgcgtgg agaaacacaa ggaccgtatg attatggcga tacaattttg acaaatgcag
    16501 caaaacaaga acttgtctca aaagcaatta ctgttccact aaaatctaca gctcaagcac
    16561 aaatggcaaa ttttgtcgta tcaaatactt caaaaaataa agaaaaatca gtagaacttc
    16621 tagggctgct taacagtgat ccagaattat tgaatgggct tgtttggggg atcgagggag
    16681 aagcatggga aaaagtcgat ggttcagatg ataaaatcaa attgctagat ggttatcagc
    16741 caaatacaca tatgtctgct tggaatacag gaaacaacaa gattctatat acacaagagt
    16801 ctattacgga tgacatgatt gccaaacgtg atcaatcgat tgctgatgca gaaacttcac
    16861 cgattttagg attcagcttc aacactgaca gtgtcaaaac agaattaagt aatatttcta
    16921 atgtcatgaa tcaatattta gatggattga atacagggac tgttgatcca gatgaaacat
    16981 taccgaaatt gaaagacgct ttggacaagg ctggctatga taaggtattg aaagaaatgc
    17041 aaaaacaata tgatgagttc cgacaagaat aataatgaat aaagacaaag gggttgtgac
    17101 aaaagacgtg tcacaacctc ttgttccgaa taaacggtgt tcaaaagcca gtttctcggt
    17161 attaagctaa atatatgtaa aaatgtggaa agccatattc acaaaatttt tcttactact
    17221 cgaaactaag cggctatttc acaaactctt ggtaaacggt gttcaatcag ctgaccctcg
    17281 gtattcgctc acaaaacgac aaaatatgag gaactatttt tccgtttgtt tctctaataa
    17341 tcaggtcaag gtgctgattg cccaaccttt ttttgtataa tgagaaagta taaacttaat
    17401 gtttggagga gaagatatgt tagggaaggt tttggaagag ttatttatcc ggatctgggt
    17461 cattataaaa ctaaccttgt atttctggat atatacattt gccggcggga tcatctttgg
    17521 attaggtgcg gcatggaaaa cagtcaatga actattttat ttgtacggat tcgagtataa
    17581 agaaatcaca ataaaaagag gctggaatat atataaaaga aattttttaa gaggcaatct
    17641 gctatttagt ttatttttat ctggtactgc tttattgagt tacaatttat atttatctgt
    17701 tcaaatcaaa gggctcattt ttttagctat tgattttatt ttactttttg ccttgctctg
    17761 cctatttgct acttatcaat acagtatgat tttagatagt gaatatacga tctctgttcc
    17821 taatctgcta aagctaagtt ttatttcggt tttttccagc ttttcgtctt ttctaaaaat
    17881 aattattggt agcggtataa ttttaggcgt gacttggcaa ttcaaaggat tgatcctgtt
    17941 tggtgtcatt ggtcttttga cggtttggaa tggtacgatg acaacacatt ggcgtgaaga
    18001 attagataaa cagttggaaa gttatgaata agtttcggat tctattttca aaaggaacct
    18061 tactaaatcg tctgttgcgg aaatacgcgg ttatcatgat cggtgtaacg atgactgcta
    18121 ccgttatttt tagtatccat acttgggaac aaaatcaaaa acaggcagaa aacatgacaa
    18181 gtgatgccgt tcaaagcaca agcagaatgc tgaatgataa aacaaccttg agtaggatca
    18241 tcaaaaacca gcttgtaggg aattccgaaa agatcgaaaa tgtgacgacc tacttaacaa
    18301 aacccataga tcagtatctg atgtatgtat acgaacagca aaacagtacc gatgaattag
    18361 tttctttccc aaatcaaatc aaagatctct acgcaaatta tgaagaacta agtgcgatat
    18421 atatcgtgtt gaatcaacta ccggagtatt atgaatcttc tagagaaaac aaaggtgggg
    18481 aaataaaaaa ggggacacca aaattactag acgcctttta tatcaagttg cctatcacac
    18541 aaggaggagc tgagtcagga agtattttta ttggttttca aaagaaagaa ctagatatga
    18601 ttttagaaaa tctaacgtca ttcaatggac tctctttata catgatttct ggaacgacaa
    18661 atcgactata cacattccat gataataaaa tagctaaaga aacgtttgaa agacaagaaa
    18721 tgatcatcac agagagtctg aagaaaaatt cacaattgcc gattgacgat ctggaaaaaa
    18781 acaattttgt tcaacaccaa gaactgtctg atgattatcg tatattagct gtactagata
    18841 aaaaaagtgt aaaaatcgaa acgggaaaaa atcttgcccc gctgatcatt ggtatcatta
    18901 ttttagacaa tatactgctt atctttcttt ataaaacatt caaacgatat tcacagcaag
    18961 tatctatcgt catgcaggcc atggatcaaa cagcagcagg gaatttagag acgcggatcg
    19021 acataacaaa cacggaatat gaactgaagg aactttcaat cggtatcaac gaaatgttgg
    19081 atagcatcaa tcagtttgta gaagacatct acaaattaga aatcaaacag caagacgcac
    19141 atatgcgggc gcttcaagca cagatcaatc cacacttttt atataataca ttagaatata
    19201 tccgaatgta tgcaatcagc gaaggaagtg aagaattagc agatgttgtg tatgcgtttt
    19261 ccgctttgct tcgaaacaat acgaatcaag agaaaacgat cactttaaaa gaagaactgg
    19321 acttttgcga aaaatatgtc tatttgtatc aaatgcgtta tcctaatcga gtagcctatc
    19381 attttatgat cgatcctgat ttggaaaaga tcgaagtacc taaatttgtg atccagccat
    19441 tagttgaaaa ttattttaaa cacggtattg attttactcg attcgataat gcgctaagtg
    19501 tcaaagtctt gcaggaaggc aaacgggtaa ggatcatcat caaagataat ggaaaaggga
    19561 tgactgaaaa acggctaaaa cagattgaag aaaaactgtc tcatcctaaa gtggaacttc
    19621 acggttctat cggtctgcaa aacgtgaatg aacgtttacg tgccagcttc ggcagcagtt
    19681 attatatgtc gcttgagaat aatgagacag gtggactgac cgtttctatt acattcaagg
    19741 agggatgagc gtgtatcaag tgttattggt agatgatgaa tacatgattt tgaatgggtt
    19801 aaaaaagata attgattggc aaagtttagg ctttcaaata gtagcaacag cagagaatgc
    19861 caaagaagga ctagctgtac ttgaacagcg acagattgat ttagtagtaa cggatgtgac
    19921 aatgccagaa ataaatggac tggaatttat tgaagcggct caaaaagaac gtcataattt
    19981 tgaatttatg attttatcag gataccaaga attcgattat ttgaaaggag gtatgcaatt
    20041 aggcgccgtg aattatttga tgaaacccgt gaataagttc gaattggttg aaagcctcaa
    20101 gaaaatcaaa acacggttag atcagcaaaa tgaacaaaaa aatcaacaag aaatctatca
    20161 agaactgtta ttcagtcaat ggttgaatga agaattggat gaaataagtg aagaagaaat
    20221 aataggacaa ataagtgaga agcagcatag gatagtattg attcaactgg caagaactca
    20281 tgatactctt atcaatagat ggttgcaaga acggcaacaa atcttttact atcaacgaaa
    20341 ttacggagac cgtgtattga tcacgttgtt gttggaggca gatgaagttg atggcttctg
    20401 ttgttttgtt caagaaaact ttcctgatca ggaatggctg atcagtatcg gggaagagac
    20461 agattctttg gacaaaatcc ctgaaacatt ccaacaagcg aaagacaatc tacagttgca
    20521 tcaattttat ggagataaag acgagcatgt tttttacgca gtacaagcag aaacaaaaga
    20581 tcaaaccatc gatttttcaa gtttcagacg cgtgctgcaa aataaacaat tggaagtcgc
    20641 tcaaaaaatg atcactgatt tttttgaaca gtttcagtta gcagccatga tgccggaaga
    20701 tatacgatat tccagttttt tactgtttat ggagattcaa cgggaattga ttgatctgga
    20761 agatgaggaa tatttacaag gaatcgaaaa aatccatcag gcaaaaacgg tgcaagaact
    20821 tcagcagcta cttctgtcat tcatcaaaaa gcatcagaga cagaaaaagt acagtgacaa
    20881 tgtggaaaaa gtaatcgtaa tcctgcacca gcattatcaa gaaccactta cactcaaaga
    20941 agtgtcagaa aacctgcatt taaatgtcat gtatctagga cagctgttca aaaaagaaac
    21001 gaaaaaaagt ttttcagctt atttgaacca tttacgtatg gaaaaagcga aacaactgct
    21061 tttgcacagt aatcaaaaca tcaatgagat agcaagtgag attggctaca acaacaccac
    21121 gtatttctct aaattattca agaaaatcgt cggcagatcc cctaaagagt accgagaaaa
    21181 cagtggagaa tcataaaaaa aaagccaatg taatgaaata acttataaaa aattgtctag
    21241 aaatctaatt ttgggctgtt cttattactt gaggcaaggc agctttttca tgacctctcg
    21301 ataaacgg
//
LOCUS       DADGHT010000048        21302 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.048, whole genome shotgun sequence.
ACCESSION   DADGHT010000048 DADGHT010000000
VERSION     DADGHT010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.048"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="JX887_001598"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="JX887_001598"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAX1257590.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="JX887_001599"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="JX887_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAX1257591.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVDCREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="JX887_001600"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="JX887_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAX1257592.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="JX887_001601"
     CDS             complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="JX887_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAX1257593.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="JX887_001602"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="JX887_001602"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAX1257594.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="JX887_001603"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="JX887_001603"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAX1257595.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="JX887_001604"
     CDS             complement(8053..8523)
                     /locus_tag="JX887_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAX1257596.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="JX887_001605"
     CDS             complement(8569..8994)
                     /locus_tag="JX887_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAX1257597.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="JX887_001606"
     CDS             complement(9061..9330)
                     /locus_tag="JX887_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAX1257598.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="JX887_001607"
     CDS             complement(9341..10936)
                     /locus_tag="JX887_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAX1257599.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="JX887_001608"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="JX887_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAX1257600.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="JX887_001609"
     CDS             complement(14489..15049)
                     /locus_tag="JX887_001609"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAX1257601.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="JX887_001610"
     CDS             15402..16376
                     /locus_tag="JX887_001610"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAX1257602.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="JX887_001611"
     CDS             16546..17946
                     /locus_tag="JX887_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAX1257603.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="JX887_001612"
     CDS             complement(18024..18746)
                     /locus_tag="JX887_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAX1257604.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="JX887_001613"
     CDS             complement(18825..19331)
                     /locus_tag="JX887_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAX1257605.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="JX887_001614"
     CDS             19454..21253
                     /locus_tag="JX887_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAX1257606.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLFQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
BASE COUNT         5925 a         4668 c         3840 g         6869 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaatc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttttca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ct
//
LOCUS       DADGHT010000049        20393 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.049, whole genome shotgun sequence.
ACCESSION   DADGHT010000049 DADGHT010000000
VERSION     DADGHT010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20393
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.049"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(383..1849)
                     /locus_tag="JX887_001615"
     CDS             complement(383..1849)
                     /locus_tag="JX887_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1257607.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(2140..4224)
                     /gene="cadA"
                     /locus_tag="JX887_001616"
     CDS             complement(2140..4224)
                     /gene="cadA"
                     /locus_tag="JX887_001616"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAX1257608.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            complement(4366..4545)
                     /locus_tag="JX887_001617"
                     /pseudo
     CDS             complement(4366..4545)
                     /locus_tag="JX887_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308695.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            complement(4749..5108)
                     /locus_tag="JX887_001618"
     CDS             complement(4749..5108)
                     /locus_tag="JX887_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAX1257609.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(5138..5479)
                     /locus_tag="JX887_001619"
     CDS             complement(5138..5479)
                     /locus_tag="JX887_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257610.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(5476..6150)
                     /locus_tag="JX887_001620"
     CDS             complement(5476..6150)
                     /locus_tag="JX887_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAX1257611.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(7326..8624)
                     /gene="asnS"
                     /locus_tag="JX887_001621"
     CDS             complement(7326..8624)
                     /gene="asnS"
                     /locus_tag="JX887_001621"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAX1257612.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(8664..9854)
                     /locus_tag="JX887_001622"
     CDS             complement(8664..9854)
                     /locus_tag="JX887_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAX1257613.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(9875..10402)
                     /locus_tag="JX887_001623"
     CDS             complement(9875..10402)
                     /locus_tag="JX887_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAX1257614.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(10449..13238)
                     /locus_tag="JX887_001624"
     CDS             complement(10449..13238)
                     /locus_tag="JX887_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAX1257615.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(13385..13585)
                     /locus_tag="JX887_001625"
     CDS             complement(13385..13585)
                     /locus_tag="JX887_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAX1257616.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(14038..14358)
                     /locus_tag="JX887_001626"
     CDS             complement(14038..14358)
                     /locus_tag="JX887_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257617.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(14861..15979)
                     /locus_tag="JX887_001627"
     CDS             complement(14861..15979)
                     /locus_tag="JX887_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257618.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            16450..17757
                     /locus_tag="JX887_001628"
     CDS             16450..17757
                     /locus_tag="JX887_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAX1257619.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            17878..19077
                     /locus_tag="JX887_001629"
     CDS             17878..19077
                     /locus_tag="JX887_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAX1257620.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(19104..20372)
                     /locus_tag="JX887_001630"
     CDS             complement(19104..20372)
                     /locus_tag="JX887_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAX1257621.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVRKGILFLPIVKRMKEKNKV"
BASE COUNT         5900 a         4344 c         3559 g         6590 t
ORIGIN      
        1 aatggtgttc aatcagctga ccttcagcat tagctcaaaa agcggcaaaa tatgaggagc
       61 tatttttccg tttgtttctc taatactcag gtcaaatcgc tgattttaca acctcttcct
      121 taaacggtgt tccaaagctt gcatctgcgg taataagccc agccaaacga aaaatatgag
      181 gggctatttt tgtttggctg ttcttattac ttgatgcagg acagcttttt cacaacctct
      241 gattcacggt gttccagaag tagcttcttc gaaaaacaag ccgaaacttc acaaaaattt
      301 gagaagcaat tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc
      361 tcttgtaaca agtatttcta ttttaaggct gaaccactgt ttctggttca gtgatttctt
      421 tgtttttgtc tcgacgagca attgctggca agatcatacc taataagatc aagacgattg
      481 gtgtgatgat attcgtaaat aattggaacc accatgcttt aggatcagca gtataatcta
      541 cttttggcac cattcctagg atacatgcaa acgcagtgaa ggcaaagcac caagcaccaa
      601 agataaaacc gatttttgga tttttaacaa atttatattc agaattgaat ttcttataag
      661 ctttattcaa catcatatat gccaagaaca cccataggta acgcattggc atgacaactg
      721 agttcaagtt cgtcaaccat tttactaatt cattcatatc tttgatacca aaaatcggca
      781 acaaaataat gattcctact agtatacctg tcagaagata accattcacc aatgtacctt
      841 tacgattacg tttacgtagc cagtttggta caaattctgg atccgcatct gctaacaaga
      901 tttttagtgg tgcatcaatt gaaaaggcta atgcggagat ttgtccaatc atgtttgtca
      961 atgcgtaaat gatcatcaat gagttaccga taccatagta attacctaaa atttgaaaag
     1021 cactgtatgc cccatttgcc atcaagtctt taggaatatt atcactagca aacagcatac
     1081 ccattgcgac tgagcctaat acagcacaaa tccctaccat tgctgctaag aagatcatcc
     1141 ctttaggaaa ttcctttgca ggatttcttg tagagttgac ataaggggat attttttccg
     1201 cccctccaac tgcaaatact agcatcgaaa cggttgtgaa ataactgaaa tcaaatgttg
     1261 gaatatatgt tttcacttga ttcatatgtg gtgtggcaaa ttccatcgtt ggattgatga
     1321 acggtgccgt tacagctaaa agaataaata agatcgacat gacgaacatc gctgttccgg
     1381 ccagtccgcc aatcactttc aaagtagaaa gtccttttgt tgataaatat aaaaaggcaa
     1441 gaaatataat aagtgaaata actgctacca tttgtactga catcgtattt acgatatttc
     1501 catttccttg gactgcccaa ccaccagcaa tcagaattgc ttgaggcttt tgtgccaaat
     1561 aaggaatatg gacgacccag taagtccaag cggcatagta tgccagtcgt ttattagatg
     1621 tcgtattttc gacccatgaa ctgacgcctc ctttactatc cttgaaggct gatcctaatt
     1681 gtccaacgat caatgcgtat ggaataaaat aaatggccaa aatcaatagc caagaggtga
     1741 caactgatac tccttgctga gcatagttat taactacatt ccccatgccc caaaccatgt
     1801 taaatgcaat taacgcaaca gtaaaccagc gtaattgttt gttgttcatt cgttctctcc
     1861 tttatgataa aaatttgtta tccagatgta atcatattca atttttaaca aacttacaag
     1921 acagtgttat tttatgtgtg tattctttta tttaatacac atcgtttttt catatttttt
     1981 ccatcaaaaa aataagttat tttcttttat ttcattgacc ttattgaatt tcaagctatt
     2041 ttgaattttc tgcaaaatta aaaacattag ttattttata atcctatcta ttttctttac
     2101 atttttcatt aagaaaagga tataaaaaaa agaggacgtt cattcgtcct ctttttttac
     2161 atgcaagctt cgcatggcat tcaaaacagc taatactgtc accccaacat ctgcaaatac
     2221 tgcatctccc attgatgcaa aaccaaaagc acctaaggca agtaccaaaa tttttatccc
     2281 aatagcaaag acaatgtttt gtttgacgat tttcaatgtt ttctttgcta aatggattgc
     2341 ttctgcaatc ttcgatggtt gatcattcat gatgactaca tctgctgctt caattgcagc
     2401 atcgcttccc aatccaccca ttgcgattcc tacatctgct cttgctagca ccggtgcatc
     2461 gttgattcca tctccgacaa atgcggtctt tttattgttt ctttgtaaga tttcctctaa
     2521 ccgctgcact ttatcttcag gaagcaattc gctatatatc ttgtccacgc ctacttgctt
     2581 cccgatatga tcagcaattt ttttcgagtc gcccgtcaac atgactgtgt tcttcacacc
     2641 agcctgtttt aattgaacca atgcgtctac ggcatcttct ttcaaggtat ctgcaataac
     2701 aagataacca ctgtaacttt gatcgatcgc tagataaagc aatgtaccga tttcttgact
     2761 taaaggaaaa gagatttcaa atctttccat caatttgtga ttacctgcta atacttgttt
     2821 gccatcaact tcagctaaga tcccttcacc tgcaaattcc tggatattag ttgttggtaa
     2881 aagcggacct gcgtagcctt ctaaaacaga ttgagcaatc ggatgtgtag aaaactgttc
     2941 tgcactcgca atatattgca tgaatttctt tggatcgatt tttgtatcga tcgtctggat
     3001 cgaaaagtca cctttcgtta atgtgccggt tttatcgaat accactgtct cggtttgcgc
     3061 aagcaactcc aagtaatttg aaccttttac taatacaccg attttacttg cgcctccgat
     3121 accgccaaag aaactaagtg gcacggaaat cactaatgca catggacatg agatcactaa
     3181 aaatgtcaat gctcgataga tccattcaga aaacgccgct ccagaaacaa caagtggagg
     3241 taaaacagct aataaaacgg ccaatcctac aacgactggt gtgtaatagc gcgcgaattt
     3301 agtaatgaaa ttttcagctg gtgctttttt actgctggca ttttctacta attctaataa
     3361 tttgctgata gtagaatttt cataagattt ttctacttga actaaaaatg gtttattttt
     3421 attgataaat ccgcttaata ctgtttcacc aacatataca gatttaggga ctgattctcc
     3481 tgtaagtgct gacgtatcga ctaatgattc tccttcgatg atcgttccat ctaacggtac
     3541 acgttcacca ggcttcacaa gtacaaactg accgatctgc acgtcttcag ggttcacggt
     3601 catcaatcct tccgtcgtct gcacgtgagc tgtttctgga cggatcgcca tcaattcgcg
     3661 aatcgatttt cttgaatgac tgactgccaa tccttggaaa tactcgccga tttgataaaa
     3721 tagcatcact gctacggctt ctggatattc accgatcaac atagcgccaa tcgtagcaac
     3781 agacataaga aaattctcat caaagatttt tcctttgacg atattcatca ctgccttctt
     3841 cactacatca tatcctatca gcagataaat caataaatac cctatcaagc gaattggttc
     3901 attaaaatca aataatagca ataaagcgat acctgcaagg gaaaataaaa tccggaacag
     3961 cgtatttctc tctttttcat ttccatgttc agatactttt tccttatcta tttctgttac
     4021 tttgacatct ggttctaatt ccttcactac tttttttgtt tcttgttcaa tcgtagccaa
     4081 atgatcttcc tctgcgtcaa tcgttagttt tccagaagtg aagtttaccg ttgcttcctt
     4141 gactccattg atcttctgaa ctcctttttc gattttcatt gcacagttcg cacaatctaa
     4201 accttctaat ctgtaacttt tcattttaat gacctcctcg cctcaacata tgaacatctc
     4261 ttcataacta attataaatg aatggttatt catatgtcaa ggtatccgaa agaaaaaatg
     4321 aaaaacatct gcatcggaaa atttcttcca tacagatgtt ttggcttatt ctttcttttt
     4381 ctcttcgatc attgcccctg ctcttatcca acccgcactt gccttcttga tcttgacagg
     4441 atagcaacta agtttgaagc ctgttgctgg caatttgtct aaattcatta atttttcgat
     4501 aggacaatat cttttttcaa tccctgcaaa atgtccttcc cagatattcg aagctccact
     4561 acgctttcaa aaatatagaa agagttcttt aatgaaaatt atttcaactt tccataaaca
     4621 gtaatcccat ataaataaaa gacgtaaaag tcacatggga gaacttatac aggaaaacac
     4681 atagagtcag gtgaaataca tgtatcccac ctgactctat gcgttttcta acctttatta
     4741 ttctcttttt atacaatttc tgcaccgaat ggcatcaacg ccaatcgagc aagtttgaaa
     4801 gattgcttgg caaaaggtat ccctatgatc gtgatacata gaaggatgcc gctgacgaca
     4861 tgtgcgagag caattggtag gcctgaaacg atcagccaga tgatattaac gatcaatgac
     4921 atgccagact ggtgataaat tacttctttg ccaaaaggcg caaaagaaag ggaggcgatc
     4981 ttaaaacatt gcataccgat tgggatacct atgatcgtga tacaccaaag tatccccgct
     5041 gctaaccagc taagaccacc gattagtccg ccgaatataa accagatgac atttcctaaa
     5101 caactcattg tatttctcct tctattactg tttttgatta aaactgggca aaaattgatt
     5161 ttattcttct ttttttagct tccagcatca agtattctgc aaattttttt tggatttctt
     5221 ccgtattttc ttttgttact aatgtgtgtt ggattagttt tcctgatggt cgctgatcca
     5281 cccgttcttc tgactgttgc acgtccgctt gcgcaaatcc gataatccgt ttttcttttg
     5341 ttacagcaac gagcaatagt ttattcttat catttaggtc agctgccgtt tttgctttta
     5401 cgaatgattc tggatgatca gtaatcagct gattgatttg aggtaaatct tcttttactg
     5461 cccaccgtat ttccatcatt tctcactttt ctttcgctca tttttatctc cactaaaaaa
     5521 atcgactgcg gcaattgcat ctatccagct ttgtgcaatg atctcatgtc cgccaatcgt
     5581 tgggtggacc ccatcttctc ttgtatattt cgaaaaacca taagcaatcc ctaaagcatt
     5641 gaatatgcca tctaaaggaa ccagcaatgc gccatattcc ttagcaagtt tacgaacaat
     5701 ttggatttta gggtctaagt ctttacgcca gccatgacgg tcgtcggtta taggaagtac
     5761 aaacggctcc atcaagatga tgttgcagat ttccgctgtt tgaagttcat ttagtaattt
     5821 tcgataaacg gattcaaatt gctgcgcaga tttctcagtt ccgaatatag cctgatcgct
     5881 agtattatgc caggtatcat tgattccgat caaaatcgat acatagtcag gttgtaaagc
     5941 taaacaatct tcttgccagc gtacttgcag atctgcaatt ttgtctcctc ctatcccacg
     6001 gttcatgcat tcaaatttca tcgttggata ttgggagatt agttttccgg caatcaaaag
     6061 tggataacct ttacctagat cagttgcttc tgctcggtct cttcctgcgt ctgtaatgct
     6121 gtcaccgata aataatatac gttttttcat ttgtcaaaaa ctcctttttg aataaaacga
     6181 tgattttctt ccttatatta tcccataagc cctatcaaga cgaaagagaa aatatatgta
     6241 taaaaaatga caccagccta gtcccttcaa tcaattgaat gaacgctcat caagtgtcta
     6301 gttttttata ctttttttct taacgtgccg gattcccctt gattccttcg ttgtttggtc
     6361 cagagaaatc gatcacacct aagcttccgt caatcagacc actgatgacg ccatcagaac
     6421 atatatttat aggctcatct aagacttcca gtaaatgttc ttttactaat atctcttcta
     6481 gattgcttgg gatagattgg tcataacttt atctggtccg atgatttcaa ggatgaatta
     6541 aacttacata tggatcattg catgctgaaa atacggacct actccatctt cgaatgttac
     6601 tattagtttg ttttcaggta ctagatgctg ctttatttca acagcagaag catcatcaaa
     6661 tcagatttcc atttgaataa ccttctttgt atatgtttga ttgattgcga tttcgttata
     6721 gaaccttgtg aatcaaatag caatttcttt tgctttcttc tcttgtctgc tggaaacttc
     6781 ctttatcccg tattttaaaa aaagaactgc gagagttcgc agttcttttt tttaaataaa
     6841 cgttgctctc cggccaactc ctcggtcaca agtcacaata gtcatcaaac atgaaaaact
     6901 gttttttgaa attactcctt gtgactcgga gctgaacggc aggcgcacaa cctcttgata
     6961 taaacggtgt tcaatcagct gaccctcgat attagctaaa aaaacggtaa aatatgagaa
     7021 gctatttttc cgttttgttt ctctaatact caggtcaagg cactgatttc acaacctctt
     7081 ccttaaacgg tgttcaaaag ccagtttctc ggtattaagc caaatttatg caaaaatgtg
     7141 gaaagccatt tccacaaaat ttttcttaat actcgaaact aaacagcttt ttcacaacct
     7201 ctccactaaa cggtattcaa aagcttacat ctgcggtaat aagtcccgcc aattcaaaaa
     7261 catgaacagc tgtttttgct tggctgttct aattacttga tgcagaacag ctttttcatc
     7321 acctcttatg gataaattcg gttcaacaaa cgtgggaatg gaatagcttc acgtacatgg
     7381 tcgataccag caatccaagt gactgttcgt tcaaggccta gaccaaaacc agagtgcgga
     7441 acagaaccgt atttacgtag atcaagatac catgaatatt ctttttcatc caaaccgtga
     7501 ttacggattt gttctagcaa gaaatcatag tctgttgccc gttcgcttcc gccaataatt
     7561 tcaccgtaac cttctggtgc gatcatatct gcacaaatta ccacgtcttc tcttgttgga
     7621 tgtggtttca tgtagaatgg cttgatggct tttggatagt ttaggataaa gacaggctgt
     7681 tcgaatgaat tcgcaatgaa cgtttcatga ggtgaaccaa agtcttcgcc ccattcgatg
     7741 tcatcaaatc catttttctt cagtaattcg attgcatcat cgtaagtaat acgagggaat
     7801 ggcaattttg tataagtttt taagacttct ttgtctcgtc ctagtacatc taatgcatat
     7861 tcgcaatgat ctaaaacatt ttgtactaag aatgctacat attgttcctg tacttctaaa
     7921 ctttcttctt gatgagtgaa agccatttct ggttcgatca tccagaattc gatcaaatga
     7981 cgtcgtgttt ttgatttttc agcacggaaa gtcggaccga atgaaaagac ttttccgaaa
     8041 gccatagcag cagcttccat gtataattgg ccactttgag ataaataagc tttttgatca
     8101 aagtaatttg tttcgaatag atccgtagtg ccttctggtg cagaaccagt caagatcggc
     8161 ggatcgattt tgacaaaatg atgttgatta aagaattcat acgttgcacg aatgatttca
     8221 tttctgatct gcataatcgc atgttgtctt gaagaacgca gccataaatg acgatgatcc
     8281 atcaagaaat ctgttccgtg ttcttttggt gtgatcggat aatcgtggct ctcgcttacc
     8341 acttccacat ttgtaattcc gatttcataa ccaaattttg aacgactgtc ttcacggatt
     8401 tctccagtta ctaacacgga tgtttcttgg tgtagatttt tagctgtttg gaaaacttct
     8461 tccgacactt cgctttttac aactacacct tggaaaaagg ctgttccgtc tcttaattgt
     8521 aaaaatgcga tttttccgct tgatcgctta tttgcgaccc aagcgccgat tgttactgtt
     8581 tctcccacat ggtttttcga atcgatgatt tgaatttgtt ccacgtatga ctctcctttt
     8641 atattccttg aatttcttca ggattaattt tgacttttac tctcaataaa ttgcttgatt
     8701 ctgcgtaccg cttcttctaa cgtagcgcga tcagtggcat aactcatgcg gacattttct
     8761 ggtgccccaa agccttcgcc agtcacaagc gctacccctg tttcttctaa aagatcttct
     8821 acccattgtg tgacattttc atacttacac atgcgtagcg tttcttttac attaggaaaa
     8881 agatagaaag ctccttgcgg cttttcaaga gaaacacccg gcagttctgc cacaagcgga
     8941 tataacgtat tcaggcgttc ttcaaaggcg ttccgcattt cttctactgt atcttgctca
     9001 cctttcaatg cttcaacagc tgcatattga ctgactgctg tcggattgct agttgattgg
     9061 gaagcaacag cgatcattcc attgatgatc acaggatttc ccaccgcata accaatgcgc
     9121 cagcctgtca tcgcatatgt tttagacacg ccgttgatga tgatggtctg atttttgatt
     9181 gcttctgaaa tcgttgcaat tggagtaaac tcattgccat tataaactaa acggccataa
     9241 atatcatcag caactatcaa aatatcattt tttactgccc attcaccgat tgcctgcagt
     9301 tcattcttgc tataaatcat tccagtcgga ttcgatggag aattgatgat tacggctttt
     9361 gttttttctg aacgtgcttg ttctagctgt tcaacagtaa ctttccagct attggattct
     9421 tcccctttca caaagacagg aagtccttct gccagtttta cttgctcacc gtaactgacc
     9481 cagtaaggca caggaatgat gacttcatct tgcgggtcaa ggatcgtttg gaaaagggta
     9541 tacaaagcaa atttcgctcc gtctgttacg actgtttgtg aaggttcata gacaagtcca
     9601 tagtttttct tcagataatc aacgattgcc tgtcgaagct ctgggattcc tgctgttggt
     9661 gtataatagc tagctttccc attgcggatt gcttcgattg ctgcttcttg gatgttttct
     9721 ggtgtcgcaa aatccggttc tcccacagtc aaactcagca catctctgcc ttttgctttt
     9781 aatgccttgg cctttgccgc agctgccaaa gtgacagacg gttctaatcg ttttgttctt
     9841 tttgataact ccatcccatt cattccttta ccttttaaat tcccttgatt gtcttgactt
     9901 catctccaga ttcaaagcca atcaggtaat aattcagttt cccatttgtt tcttttccta
     9961 ctacttccca cacaggctga tcatcataca tccctaaagc agctttttcg atttggattt
    10021 caggatgggc cgcagcaatt gtctgttttg cttcgttttc agtcagtccc tttgtttgat
    10081 ccaatacttt tactttttca ccagatttag gaatgataac ggcgatttct tttcctttat
    10141 catttgtacc tgtcagtgaa aagtatgtct tctttcgagt aaaccaataa aaatgatcgg
    10201 tttcctcaag atttgcatat ttctttgcga tttctactgc ttctttcttc gcctgcaccg
    10261 ccggacgact ggaacgcaag taaaaaatcg agctgatcac gatgaccgct aataaaaata
    10321 cgatcaagcc aagtaacacg cgattaatcg ttttttcctt tgtctgtttt ttcttcaagg
    10381 gtcgtcgctc ctttatcttc attccttttc attatagcag attttaatta tgaaaaaaga
    10441 cagctcctct aacttccttc ttcatttttc tttaagaatt catggatatc ctgatagatt
    10501 tcctccatag ctagctcttt gatcggtact tttttcggta atgcatggat gatccgtgcg
    10561 ccatattttg cagtgactag tcttcgatcc aaaataagca atacgccacg atctgtctcc
    10621 gtccttatca agcgacctaa tgcttggcgt aacttcaaag ctgctttagg tacggattcc
    10681 tggtaaaaag gattgatccc ctctgattct aaataagcgt tcctagcttt gaccatcggg
    10741 cgaagcggat tatcgaaggg taaacgtgtg actacaacga tctgcaaagc atctccaggc
    10801 aaatctacac cttcccaaaa gctgtcagcg ccaaacaata cgcttttttc tgacaaaatg
    10861 aagcgtttca aaagcttctc ccggcttcca ccaaaccctt gagctagtat ttctcgtcct
    10921 ttttctagca tagacagatg cattttctga tagaccttct gcaaaacatc atgagaagtg
    10981 aataacacaa gtattggccg atcttcttgt tcgatcagac ctgtaagtgc tgtctctaaa
    11041 taatcgatat atgcttgatt gctgacttga tggacggcag gtgcctcttt tggcacatag
    11101 atccttgcct gtttctcata atcataagga gaggcaatca ctttaagagg tgctgcttca
    11161 atgccaagcc tcttagagag atagtgtcga ttagggccga tcttcagcgt tcctccaata
    11221 taaagaatac gatcatatcg aggataccaa acagtcgacg gcaacatagc cgcttgaaaa
    11281 tcatggagat gaaaaatcat ctgctgcgct gtgttcccag gaacgaacca atggatcaaa
    11341 tgatctcgcc agtcttccag ccattgatcc atcagcaagt attgcttgtc taattgatca
    11401 aataggctat ataaacttgc taaatcgatc cgcatctggt ttgtccagct ttcttggata
    11461 atctcaaaag tcagacgcat ttgtgactgt agctgctgga tctcctgata aaaaagctgc
    11521 aggtgatcaa tggctgtccc agattccagt ggcagctgat ccaacatctc ttttgtcatc
    11581 atgacttctt ctggatactg tccgttaggt tgcttgccgc tcactaaact cattaatcct
    11641 tctgccatac aaatctgtgc ttcgcatagc gcagaaagtt cttctcgata aatcgataac
    11701 cagcgtaagg cttcatgttc tttcggtaaa tagctttgta ttcggtcaaa cagctgattt
    11761 ggttcttcta attgctggat ttgtttatgg aaatagttaa tacttaatcg tttgtcattt
    11821 actttttcag cgatttccgg caaatgatgt acttcatcga tcaacaaaaa tggactagct
    11881 ggaagcaatg gttcttttcg ctgtgtttct tgtactaaaa acgcatgatt gacaatcaaa
    11941 aaattacttt gcctgatttt cttttgcaag aaacgaacaa agtcttgttc gtaaaatgac
    12001 tgatttcttg ctaaaaatcc aatacctctg tgcgcgatat ctgcaaagaa tgaatggttc
    12061 aaatttgtta aatgtaattc atccaaatca ccagtcttcg tttgcgtcag ccaaactaag
    12121 accgccattt gatacaaagc atattgtttt tgttctggcg gttccacaag tgtgccttta
    12181 aaacgctgca aatcaatata gtggcgatag cttttgataa ttacaggttg tatgggctga
    12241 tctagcaatt gattcagcaa tggaatgtct ttttctatga tctgctgctg caaaactagc
    12301 gaaacggtac tgatgacagc gggtttttca ggtgtagcca aataactcaa tggcagcaga
    12361 taaccgattg ttttacccat tcctgtagct gcttcgatca tcaaatcttt tgattcatct
    12421 tttgtgaaat ggtcgtagac cgcattcatc agtctgttct gttcttttcg atacatcagt
    12481 gttttaccaa acattttttc ttttgcttgt ttttttcttg gatatgtccg ctcgccataa
    12541 tggacggatg tgaatagttc cacttctttt ttctgcaaag ctagcccatc gacgatttct
    12601 aatgagggat caagtggctc tggtttttct ttcatttctt caatcacatg ataaatgaaa
    12661 cgactcgtat ccatacctgt gtgtctactt aatcgcgcaa tctgctctaa cgtgatgatt
    12721 ggcaattttc tcatccgttc ttcgatcagc aaaagaagtt gacctgtcac ttcggcatca
    12781 ctatctgcct gatgaggatt ctcatgaata aatccaaggc tttctgacaa atcagctaag
    12841 cgaaagcttg gttccgtcgg caagaaaatt tgtgcaagtt ctactgtatc gatgcctggt
    12901 atcttcaaac taggaagtcc gcatcgcatg agttcatggt tcaaaaaatt ataatcaaaa
    12961 taaatattat gcgcgacaaa tatggtgtct gccaaaagat tgtaaatcgt ttgggcgaca
    13021 tcttcgaaat aaggcgcttt ttggacgcgt tgattcgtga tccctgttaa atgctggatt
    13081 tgttttgaaa tcttccgccc tggatgaata tcgatcgaaa aacgtgaagt gatccgacct
    13141 gattcaatca tgacgcagcc aaattggatg atccgatctt cttttggatt cgtcccagtc
    13201 gtttcgatat caacgactgc ataagttctt ggtttcaaaa tatcttcctc ttctcctgcc
    13261 tctaatgttc ttttgaaatt atactacaaa gtgcagaaaa atactctcat cgctttttaa
    13321 agaaaataga caaaaacgcc cagacacgca aatgtctggg cgtttatttt ttagtatagg
    13381 ttaattaagc tttagtaacg tttgttgctt gaggtccgcg ttggccttct tcaacatcga
    13441 aagttactgc ttggccttct tctaaagttt tgaatccgtc gccttggata gctgagaaat
    13501 gaacgaatac atcgtttccg ttttctgcag tgatgaatcc aaatcctttt tctgagttaa
    13561 accattttac tgtacctgtt tccataataa aaatcctcct tgtgtatcaa cacatatttt
    13621 gcaattactt gaatggtgta tatctggaag atgtttattt gaaacaagct accacagatt
    13681 accgaacaaa aactactcct atagtatatc ataccgttta caaaaaagct agagtttttc
    13741 gacttttttt attaaaaaaa gttttctcag cgattacata aagtgaaaaa ccgaactttt
    13801 ttttaaaata aacgacatat tgttcagttg gtgttttttt gctctgatgt tcttttttaa
    13861 actaaaaaaa ttattctttc tgactactta tcggttctgt ttcaacggtc gaggctgggg
    13921 aagattcttt agtaggtctg atgttctcat ggtatttctg atagcctatg acagttacca
    13981 gaagaacaag gcaaaccaat acgaccaacg agattagttt ttcttttttg ctcatatcta
    14041 tacctcataa ataacaggat gatgtccatc atatttctga gtatgagtaa aagcaaaagc
    14101 tgcagctgta gaatgtaaga aatgccagca actttcataa tcacaggtcg gacagtacca
    14161 aaagtaacca aatcttggct gcaaagaccg ttcttctgtt tcaggaatcg cagaatcaag
    14221 atctggtgtc tgtacataaa catttttgta cagacgtgtg cctgtaatag gaaaccgctg
    14281 tgtttcttca gcaaaaactg gctgacttgt taaacttagg gatagagaca gcaaacacca
    14341 taacagtctt tttttcataa agacctcctt atcgataagt ttttcccaat taaaatcata
    14401 tctcaagaac gcccgttatt cacattttgt tcataaatga tgttttttgt atcataatcg
    14461 tcaaaaagag gtcgtgacca cgtcacaacc tcttttttaa acggtgttcc agaagtagct
    14521 tcttcggaaa taagccgaaa tttcacaaaa atttgagaaa taatttttgt caatctcttc
    14581 ttatttcttg aagctgacca cttctgtcac aacctcttcc ttaaacggtg ttcaaaagct
    14641 tgcatctgcg gtaataagcc caccaaacaa aaaatatgaa gagctatttt tgcttgctgt
    14701 tcttattact tgatgcagaa cagctttttc acaacctctc atacacggtg tttaatcagc
    14761 tgaccttcgg tattagctca aaaaacggca aaatatgtga aactattttt ccgtttgttt
    14821 ctctaatact caggtcaaaa cactgatttc acaacctctt ttaataacga agaatcgctg
    14881 tcagactctt ttcatctggc gcatcttttt gatccaaaat aaacactttt ccgccattaa
    14941 tgatcacatc atctgctaat gcattcaaca cttgacgccg atcatattct gtttcaggat
    15001 cttcaccgaa accatcagct aagtttgacg tagcgataaa taaatgtgac acttttcctt
    15061 ctttcgcagc tggaacgata tcaactaact gatcgatgaa tttcttatct aagagtttat
    15121 tgtattcttt tgattcttga gctgcgagtt cacttgacag cttcttcgcc ccttcttcga
    15181 tatctctaaa ggatagctgc gcaggagaag cagaaatcgc aacgtctgca caataatagg
    15241 gatttttagc aatttttttg aacatcgtct gattttctgg tagagcaaat aaataaatcg
    15301 gccattgttc tggattttcg aaagaatcct tcaagtacgt atcaactgct tggtaatagt
    15361 tgacccaatc gatctctact tcttcatctt ttggatttac gccatggaaa gttactccat
    15421 ctcgggctcc gcctcctcca ttagaagaga agttcaaacc gccacctgtc agttcagatc
    15481 ccaatgcagt aacgacatca accggtgccc cttctggtag agatacttct tttacttgtt
    15541 tgttgctgac ttcatacaat ttcatggagt cgcggttcaa tcccaataaa taataagaat
    15601 agttgaactg cccatttttg ataatagcca gtaaataagg aagatcactt acatagtatt
    15661 gatcgtctac cgggatactc aaacgatgga tataggtttg gtcagcagtt ataatgaccg
    15721 ctacactcgt agttgcacta cgccaaaacg aaggatctcc taacaaattt tcaatttttt
    15781 cttggaacgg ggaccagtca tgttcggaat attttttctc aaaacgtttc tttgcttctt
    15841 tcgcaaaatt tttgaatttg atctgatctt tttccacatc ttgatgggcg acatgcgtat
    15901 tcagcatgat cgtgacgaat ggtcctttag cgccttctga agtcaattgt gacaataatt
    15961 ctttatcctt ttttgccata aacgtacccc tcctaaaaaa atcattcctt tgtttctatc
    16021 taaagtctac cacaacacta tttttccata caataaaacg tatctaaaaa aataaaacgg
    16081 tttctacggt tttaaattta gctatttttt taagttatct tcataatttc ctcaattatt
    16141 tagccccagt cttcaactat tcttcatgaa atgctgataa actaagaaaa agaataaaag
    16201 aggtggatct tatgcatttg attatgattt tcagtttatt aagtattatc agtttatttg
    16261 ctttcagcgc ttcccgctta ttagatgcgg aaacacagcc tattcctgta aaagtacgta
    16321 aaaacgaccg ctaaccttcc ataacgtgcg ttcttatcct aaagtttttt cagaaacatt
    16381 gaaactctct cccctctctg ataaaatttt aatttgtagc gaaacaaatt aattacaagg
    16441 agatcggata tgtccataaa aaaaacacgt ctagtcctat tattggctag tctcattctt
    16501 tgccttgctt cttttctacc agctgttgct gtgcaagctg aagatacttt caaagtaaat
    16561 gcaaaagcag cctttgctgt agatgcgcaa agcggtaaga ttctttatga tcaagatgga
    16621 gaaaaaacca tggggatcgc ttcaatcaca aaaatcatcg gtctttacat cgtccttgat
    16681 caagtaaaag aagggaaact atcatgggat gataaagttt caatttcaga ttatgcagaa
    16741 aatttgagtg tcaccccaga tttatcaaat gttcctttgc ataaagaaaa cacctacacc
    16801 gttaaagaat tattcgactc tgcaatcatc cagtcagcca acgcttcaat ggttgccttg
    16861 gcagaaaaaa tctctggcag cgaagcaaaa ttcactgaac gaatgaaaga acaattgaaa
    16921 gattggggta tcaaagatgc aacgatcgtt aatgcatcag gactgaataa ctcttatctt
    16981 ggcgaaaacc gaccagaagg tactggagaa aacgacgaaa atcaaatgtc tgctcaagat
    17041 gtggctatcg ttgcccgtca tttgatcttg gattttccag aaatactgga tgtatctagc
    17101 actacgacac aaatgtttgg cgaaaacacg caatcaccag tagaaatggt caactggaac
    17161 tggatgctcc caggattcgt gaattataaa gaaggcgtgg acggattaaa aactggtacg
    17221 actgaacttg caggagcctg tttcgtcggt acgatcacta aaaacgatca acgaatcatc
    17281 actgtcgtat tgaatgcaga cggccatgcg gaaaacccaa gtgcccgttt caatgaaaca
    17341 gctcgcttaa tggattattg ctacgacaat tggtcagaaa aagagcttgg aaaagccaat
    17401 gcaagtatcc ctagtctaaa aaccattgat gtaaaagacg gaaaagaatc aacagtgccc
    17461 gttgtgctta aaagtcctgt aaaagtatgg gtacggaacg atatggatac tggaaaatta
    17521 acaatcacac caactcttga caaaaaacaa gtcactgaca atgagatcca agcacctatg
    17581 gataaaggaa caaaaatcgg taccgcaacg atcaccttgg cagaagataa attaggttat
    17641 cttgaagaca acaacgcgcc atccacagaa atcatcacgg ataaaaccgt agaaaaagca
    17701 aatattttcg ttattggctg gcgacgcgtc gcagaatttt tcggtaactt gttttaattg
    17761 aacaaaaaga aaaaagcatc tttccatgtg gaagatgttt ttttgctttt tctagtttaa
    17821 ataacagctt ttttcatcta ttttcgttat actgtataag aaaaaggagt tgaatttatg
    17881 aatctaacca gagatctgat ttttttggtt ctctatctta ttggggtatt ctccatcgtt
    17941 tattggcgaa aacagaaaaa ggatccttcc ttgttctttt acagcagtac atggacgttt
    18001 gcggtaatct tgacttattt tgtcgtgttg gaaatttttt attcgacctt ttattttttg
    18061 attcccttag tgtttttcag tatctttgcc ttttcctatt tttcagaaaa gcgaaggctg
    18121 ttgaatggtc ttttattcaa tattttcctc attagttttg gtatctactt gtttgtcttg
    18181 ctatacgaaa cacaaaatat ttttcttggc ggactgattg ccttgatcac gatcccgtta
    18241 ctgcttgtct ttctattcgg catttatgga ttgatcgttt ttcttttttg gaacggtgtc
    18301 acagttttac gtagagagtc gcattcatta gctaatcttt taacgttgat actagccatt
    18361 tttcttacat tgtttcttgt ttttgacttt ttcttgttaa aatatttacc acaatggata
    18421 aatgctttgt ttttctgcat cccattgatc ttgatctatc tatttatcgt attctacaac
    18481 tttttgactg tctcattctt gtatcagttc aaccgccctc gatacaacca agacttcatc
    18541 gttgtgttag gcgccgggtt gatcaatgga gaaacagttt ctcctcttct tgccaagcga
    18601 atcaataagg cgattgcttt ttattgggca caaagccgtg cgacattaaa tccgcctatc
    18661 ctattaatgt cgggtggaca gggagcagac gaaaaagtac cagaagcaat ggcgatgaaa
    18721 caatatgcca tggaacaagg aattcctgaa agagatattc ttgtcgaaac caattcgaca
    18781 accactttgg agaatatgcg ctattcaaag gaaatcatgg atcagcaaat gaaaggtccc
    18841 tatcgcgcga tcttcagttc caacaattac cacattttca gagctggtct ctatgcacga
    18901 caagcgaaac tgaaggcaaa tggcattggg gcaaaaacag ctttctatta cttgcctaac
    18961 gcgtttttaa gagaatacat cgccatcttg atgatgaaca aaaaaagaca tatgatcatt
    19021 tgcggattgc ttttcgcagg ttccgcattc ttatcactga tcactttact tttctaaaaa
    19081 aacaaggtgt gacaaaacat atgtcacacc ttgttttttt ctttcattct cttaactatt
    19141 ggcaaaaaga gtatcccttt tctgaccgct acttgctgag cagaataaat accgctgttg
    19201 cctgaacaca taaagctgat caagcagatc ataaagaagt atactgccgc ttgtgaaccg
    19261 aacaattcga tccccatcac aaagcaggca atcggtgtat ttgtcgcacc agaaaatact
    19321 ccgataaagc ccaatcctgc aagaaaagga acagaaacat ggagcaaagg cgctagtgct
    19381 gcaccaagcg ttgcaccaat ttcaaacaat ggtgtcactt ctcccccttg atatcccgcg
    19441 cctaaagaca aaactgtgaa gaataacttc ccaataaaat catagacatg tgcctgtcca
    19501 ttaaatgatt cctgcagtaa tggaagactc aatccgagat aacgttgtgt ttgcaaaatc
    19561 aatgctgcgg ctacaactac agccccacct atcgtatttc gccaaacagg atgaggaatc
    19621 cattgtgcat atcgcgcttt taaaaagacg atcgaacggc tgaataccca accaatcaaa
    19681 ccaaaagcaa tcccagcaac aaaaactttg aagaacagca acatactcca ttcaggaatc
    19741 acacccattt ggtaatgtag atgagaaaca ccatagcttt ctgtcataaa atttgcaaac
    19801 agtgcagcaa agaagctagg gaagatcgct tctgttcgga ctttcccgat tgccaacact
    19861 tctaatccaa ataatgttcc agctaaaggt gtgccaaata cagaactaaa acccgcactg
    19921 attccactga taatcaagat ttcccgttct gatttatcca atcggaacaa acgtgctgta
    19981 ttatctgcta acgctccccc catttggact gctgttcctt cacggccaac agatcctcca
    20041 aataaatggg tagttatggt tccaaacagt gtaagtggaa taagtcgcaa cgggattttt
    20101 tcttctccac catttccttg atcgatcact aagttgtttc cacgactaga aagaccgccg
    20161 tgatacgcat agagataagc aaaaagcgca ccactaactg gtagtagata aaggagccaa
    20221 ggatgtgata gtcggatatc tgtcacaact gtcaggctat ttaagaaaaa agcagataag
    20281 ctccccatga atataccgag aatcgctgtg atcaccagcc acttcagcat gtacactaaa
    20341 atgcgtactg gactcggtaa ttgtttttcc ataaaaaatt cctcctcaat aaa
//
LOCUS       DADGHT010000050        20373 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.050, whole genome shotgun sequence.
ACCESSION   DADGHT010000050 DADGHT010000000
VERSION     DADGHT010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.050"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..351
                     /locus_tag="JX887_001631"
     CDS             <1..351
                     /locus_tag="JX887_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAX1257622.1"
                     /translation="HAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEEQLLEEG
                     LRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLIDYIQLS
                     QKFEMIQKQKLLKQ"
     gene            370..591
                     /locus_tag="JX887_001632"
     CDS             370..591
                     /locus_tag="JX887_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAX1257623.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            588..1349
                     /locus_tag="JX887_001633"
     CDS             588..1349
                     /locus_tag="JX887_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAX1257624.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            1729..2238
                     /locus_tag="JX887_001634"
     CDS             1729..2238
                     /locus_tag="JX887_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAX1257625.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(2313..2852)
                     /locus_tag="JX887_001635"
     CDS             complement(2313..2852)
                     /locus_tag="JX887_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAX1257626.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(2992..3603)
                     /gene="rpsD"
                     /locus_tag="JX887_001636"
     CDS             complement(2992..3603)
                     /gene="rpsD"
                     /locus_tag="JX887_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAX1257627.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            3919..4716
                     /locus_tag="JX887_001637"
     CDS             3919..4716
                     /locus_tag="JX887_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAX1257628.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            4744..5379
                     /locus_tag="JX887_001638"
     CDS             4744..5379
                     /locus_tag="JX887_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAX1257629.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            5399..6172
                     /locus_tag="JX887_001639"
     CDS             5399..6172
                     /locus_tag="JX887_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1257630.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            6580..7377
                     /locus_tag="JX887_001640"
     CDS             6580..7377
                     /locus_tag="JX887_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAX1257631.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            7355..7768
                     /locus_tag="JX887_001641"
     CDS             7355..7768
                     /locus_tag="JX887_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257632.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            7752..10397
                     /gene="mutS"
                     /locus_tag="JX887_001642"
     CDS             7752..10397
                     /gene="mutS"
                     /locus_tag="JX887_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAX1257633.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            10415..12523
                     /gene="mutL"
                     /locus_tag="JX887_001643"
     CDS             10415..12523
                     /gene="mutL"
                     /locus_tag="JX887_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAX1257634.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            12545..13105
                     /locus_tag="JX887_001644"
     CDS             12545..13105
                     /locus_tag="JX887_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAX1257635.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(13190..15178)
                     /gene="treP"
                     /locus_tag="JX887_001645"
     CDS             complement(13190..15178)
                     /gene="treP"
                     /locus_tag="JX887_001645"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAX1257636.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            15401..16114
                     /gene="treR"
                     /locus_tag="JX887_001646"
     CDS             15401..16114
                     /gene="treR"
                     /locus_tag="JX887_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAX1257637.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            16191..16637
                     /gene="msrB"
                     /locus_tag="JX887_001647"
     CDS             16191..16637
                     /gene="msrB"
                     /locus_tag="JX887_001647"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAX1257638.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            16808..17410
                     /gene="ruvA"
                     /locus_tag="JX887_001648"
     CDS             16808..17410
                     /gene="ruvA"
                     /locus_tag="JX887_001648"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAX1257639.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            17423..18424
                     /gene="ruvB"
                     /locus_tag="JX887_001649"
     CDS             17423..18424
                     /gene="ruvB"
                     /locus_tag="JX887_001649"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAX1257640.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            18453..19031
                     /locus_tag="JX887_001650"
     CDS             18453..19031
                     /locus_tag="JX887_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAX1257641.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            19083..19565
                     /locus_tag="JX887_001651"
     CDS             19083..19565
                     /locus_tag="JX887_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAX1257642.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            19682..20056
                     /locus_tag="JX887_001652"
     CDS             19682..20056
                     /locus_tag="JX887_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257643.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         6712 a         3659 c         4438 g         5564 t
ORIGIN      
        1 catgcgtttt tgatggggcg gtatctgact gtgtttaaaa cattaggagc ctttactcca
       61 cagcttccaa agatcacgat ccttttaatg acagatttcc cattatttga agagcaactg
      121 ttagaggagg gattacggac atttttccgt aatgagtatc agctgatttt tctgccaaca
      181 gattatcggg ggagagaagt tgatcttctg atttcgacaa gtaaagtcca ccgcaaacca
      241 tgggcggatc ttgactattt tattgtgact gaagaactaa aattaattga ttacatccaa
      301 ctatctcaaa aatttgaaat gattcaaaaa caaaaactat taaaacaata acaaagaagg
      361 agaaaaaaga tgacatttga agaaatttta ccagaattga aaaaaggtgc aaagattatt
      421 cgtaaaggat ggagtggatt tgaactttat gttgttctcg tatccgatga tgaatttgat
      481 ggctgtccgg tgacgccgta cttattgatc aaaacaagtg acgaaggttt ttccagcttc
      541 gctcctacag tttgtgatat tttagcagat gattgggcga tcgtagaatg aaaaaccagt
      601 atccagatct agctaaacag gttgtattta tcacaggagc tgcttctgga attggtgctg
      661 cgcaagcccg agcgtttctt gaacaagatg cttttgtatt tggattagat caaaagttcg
      721 gtaaaatgga agaaatttct ttgcgatttc ctgaaacttt tgcctacgca ctaggtgatg
      781 ttcgacaaat gaaagaactc caacaagcgg tatcgaaatg ccaaaatcat tttggtgaag
      841 ttacgatttt actgaataca gcggggatat tggatgccta caaacccttg atggaaactg
      901 acgaatcgct gtgggatctg atttatgaga cgaatgtgaa aagcatgtat cagctgacaa
      961 aaatcatcct tcctgatatg atccgccaaa aaagcggaac gatcatcaat atggcttcga
     1021 ttgctggctt gattgctggt ggaggtggga tcgcttatac aagcgcgaaa catgcgattg
     1081 tcggatttac caaacaactc gctctggatt acgcaggaca gggtatccga gtaaaaggaa
     1141 ttgctccagg agccatccaa acaccaatga atgcggctga ttttgaaggg aaaggtgaga
     1201 tggcagagtg ggtggcaaat gaaacaccag tcaagcgatg ggcacagccg gaagaagtag
     1261 ctgagctgac gttatttctt gcctctcctc aagcaagcta catacaagga acgatcatcc
     1321 caatcgacgg cggatggttg ttaaaataac cttgtgtttt tttcaagctt ctgtatgata
     1381 aaactaaaga gagaaacaac ggttgatgat aaaaaaagtc gatgactgtt cccgacattc
     1441 gatgccgaac agccagttca aaaaattctt tttaataatc gttaatattc gaaactaagc
     1501 ggcttttcac gacctcttga tataaacgat attcaaaagc ttgcaactgc ggtaacaagt
     1561 ccagccaaat gaaaaatata aggagctatt tttatttgac cattcttatt acttgttgca
     1621 gggcagcttt ttcactacct tctgcgacac ttcagttgga attttcttcc catcctttgg
     1681 tcgcggtcat taccaagata aaattatctt gcaaaggaga aatagaacat ggaaaaaaat
     1741 aatacccgtt cagccaaacg ctggacaacg acagatgtga ctcggatggc gctagtcact
     1801 ggtttatatg tggcagtgac gctggttttg tctgtcttta gctttggagt gattcagatt
     1861 cgtctctcgg agatgttcaa ctatctgtcc ttgtataaca aaagatacat cgtcgcggta
     1921 acagcgggag tagctttggc taatattgct tctcctcttg gactgataga tgttgcagta
     1981 ggaagcgtca gcacgctgct tgtattgctt atcaactata aaatcactag tcgcatcaaa
     2041 aacatgaaaa tcaaaatggc cgtgacagca tgcgtatttg ctttttccat gtttacagta
     2101 gctggtcagc taacgatttt atatcaacta ccttttttct tgaattggtg ggtgattgct
     2161 ttaggagaat tggcatcaat gattgtcggt gggataatta tttattggat cggtaaaaaa
     2221 gtggatttgt caaaataaag atctgtttaa tttaaaatag ggcagcatgg aagagactga
     2281 atgttgagtc ttcttccatg ctgctttttt gattaatttg tatgaagaaa tcgatttagc
     2341 cgttttttca tcaagatacc gatataagct gctccagttg ccttgattgc ttccggcagt
     2401 aaaaacggca gtagtccact ggcaaatgca gttgtaaaag taagatcacc acttattttc
     2461 agccagatcg ttccgcagat caatgcagca agagagccca ttagattggc aaagattgca
     2521 tataagtaat gagcatccgt tctttcgatc atccaaccag ttatccacgt ttgtaagaga
     2581 aatccaatca aatatccgcc agttggccca aataaaacag ctatacctcc agtcatccct
     2641 gaaaatacag gaagaccaat caagccaagt aaaagataaa ctccaacaga tatcaatcct
     2701 agttttcttc cgagaaaagt tgctgttaat ccaatagcaa atgtttgccc tgtcaaagga
     2761 accaaaccaa aaggaatggt catctgagaa aggacagaaa taatcgcggc aaattccgca
     2821 gcaagtatca attctttcaa tgttcggttc ataacgccct cttttcgtta acttaatatt
     2881 tttatttggt taacgaaatt gtaaaacaaa gtgattactt tgtaaataga aaatataaaa
     2941 aaagaccagc tatccaatag atagcggtct ttttcaagaa agcttttgaa attataagct
     3001 ttggttgtag tattcaacga caagagcttc gtcgatttct ggatatagtt cgtcacgttc
     3061 tggtaaacga gtcaatgaac cttccaattt ttcagcgtca aagcttacga atgctgggcg
     3121 tccaacagtt gcttctacag cttcttttac tgttacgatg ttttgtgatt tttcacgaac
     3181 tgagatcact tgacccactt ctacgtggta tgaagggata tcaacgcgtt tgccatcaac
     3241 taaaatgtga ccatggttaa ctaattgacg tgcttgacga cgagtcgttg caagtcctaa
     3301 acggtaaaca acattgtcta aacgttgttc tagtaagatc atgaagttaa caccatgttt
     3361 accttctttg attttgctag cttttacgaa caagttacgg aattgacgtt cgttcattcc
     3421 gtacatgtga cgaagttttt gtttttcagt taattgcatg ccgtattctg attgtttgcc
     3481 acggctatta ggtccatgtt gacctggtgc gtaagggcga cgtgctaatt cttttcctgt
     3541 gcctgacaat gagatgccta agcgacgaga aattttccat gatggtcctg tataacgaga
     3601 cattaaaatt tcctccaatg aatataagtt tttggagtaa aataatccgt tgaaaaattc
     3661 ataatcatat agtttgttct tcaatcttca cctttgcagc cgcggttaca caatcgaacc
     3721 cgagacgggg caacaaacta gggatgagtt attatttttc tgctgcatta ttttacacaa
     3781 attacagtat atgatagatc atccacgaat gtcaagataa ttagtacata aaaacgcttt
     3841 acaaacctag gctgtcttta taaaatgaga gggtatgtgc aaatggaaaa aagcgaagga
     3901 agtttaagga gaaaatcaat gaatccggta tcaccattat ttgagaaaat cgatgcttca
     3961 attgaaaaga aggcgaatct ttttgaaaac agcttttcac gttacgctgt tcgagcggtt
     4021 ctcgcctgtt tgtttttgac tttaggaacg gctgtggcat ttgcgatcgc gatgaagggg
     4081 gaagatatcg cgcatggtct aggaaagatt ttatacgcat ttatgttcag ctggggtctg
     4141 gtcatgattc tatacatgaa cgccgaatta ggaacatcga atatgcttta tatgaccgtg
     4201 ggtgtttttc ggcagagact tgctttaagt aaggcagcca agattctatt tgcctgtatt
     4261 tttttcaata tgattggcgg tatattatgt ggatttctaa tttctatgac tacgccattt
     4321 caagatttaa cgttggacaa ctttatgtta gaatcaatag cagtaaaact agcaaaacct
     4381 tcagcaacga ttttggtgga agggatgttt gcgaatatcg ttgtcaatac cgctgtactg
     4441 atcagcatgc ggatgaaaga ggatgtcgga aaagtgatca cagtcgtatt catcattttc
     4501 atttttgctt ttttaggata tgaacacgtg atagcgaatt ttcctgcctt tacgcttact
     4561 tactttgctt ctcacggaca gatggatgga atgacagtca gcaatgtgtt acataatttg
     4621 ttttttgctt tggcaggaaa ttatattggt ggcggtttag taatgggact gggatatgct
     4681 tggctgaatc agtcaaaatc atcctatgtg gactaaaaag tcgttcatta aaggggaagt
     4741 gccatggaag ttttagtttt tccaaaaaat gaggaaaaag cgttacaaat ggaaaagtac
     4801 atgaaaaatc ttttttcctt tgctggagta cctaagccgg aacgcgctct tttacaacaa
     4861 ccgttactgg atgagagcaa aaatttatct atttctgaag ttttagcttt tgttcattat
     4921 tattatgaac aaatcgaaag agagtatcag tatgtagcga tcgatttagt ccagaaaaac
     4981 atcaaacggc ttacatttga agacttagtc gtattgttgc cactagttca gaaaaaagaa
     5041 tggtgggaca gcatcgactc ttggagaaaa gtatacagca catggtgtaa agcctaccca
     5101 gagcagcgtg aagaagtctt tcaattgttt gaaaaaaagg aagatttttg gctacgtcga
     5161 atagcaatca cgttgcaatt aggttataaa cagcaaacag acacaggact attgatccga
     5221 gcaatagacg aagatcgtca aacaaaggaa ttctttatcc aaaaagcaat tggttgggca
     5281 ttacgcgatt atagtaagac cgatgccgat tgggtaaaaa gacagctgac aacagatttg
     5341 agtaagttag ctgttcgaga ggcaagtaag tatttataag aaagcgagac gacaagagat
     5401 gagacgcaaa ttatttgctt ttgatattga tggaacgttg ttagattcaa acaaacaagc
     5461 tttagatagc acaagagaag cattggaaaa attacgcaaa gccggtcatc tggtcacgat
     5521 tgctacaggg cggagccgat ttcatgcgca agagatcatt cgcgatcttg attttacgaa
     5581 ctacatttta tgtaatggag cggccggttt tttagaccat gaacaagtat ataagaattt
     5641 actagatcgc gaccagttgg atgcgttcgt tcaagaagcg catcatgagc agatcgatac
     5701 agcttttgtc agcttagaca atatcaagcg ttcttcttcc aatgatgtaa cggtgatgga
     5761 agaagcgatg cattctttcg gtgctgtctt gcctgaatta gatcagtttt ttgcagagga
     5821 acaagaaata taccaagcgt tagcattttt cgatcaaaca tatgatggga agttctcttc
     5881 atatgataaa attcgatttg tccgctggca tgagaacagt gtagatgtcg tacctaaaaa
     5941 tggttctaaa gcagcgacaa ttctgcactt agcagaacaa gtaggcatcc ctcatgaaga
     6001 catcatcagc tttggcgatg gacaaaacga ccgtgaaatg ttgcgcatgt caggaattgg
     6061 gatagctatg gggaatgctg tgccagaagt acaagcagaa gctaagatgg tcactgatac
     6121 aaacgatcag gatggaattt ggaaggcatt gaaagagtta agcgtgattt aaaagaggtt
     6181 gtgaaaaagc tgttctgcat caagtaataa gcccagccaa acaaaaatag ctcctcctat
     6241 ttttcgtttt tctgggctta ttaccgcaga tgcaagcttt cgaacaccgt ttaaggaaga
     6301 ggtcgtgaca gaagtggtca gtttcaagaa ataagaaggg atttacgaaa attgcttctc
     6361 aaatttttgt aaaattacgg cttatttctg aagaagtaga tgaaacaacg tttattcggg
     6421 aaatgggact gtgacaagat gtttgtcata gtcccatttt tttattttat ttttcaaaac
     6481 taagaaatac caggaaagag ttccttttgt ttgacctttt ctttcttatt gaaaacaact
     6541 ataatataga gtgatgttaa aagagaagag gaatttagtg tgcgggtatt gtttattggt
     6601 gatgtagtag gttcaatggg acgagagatg attactgaat atcttcctag attgaagaag
     6661 aagtaccgtc cgcaagtaac gattgtaaat ggtgagaatg ccgcttctgg acgtggaatc
     6721 acagaaaaaa tctataaaaa atttttgcaa gacggcgtag atgtcgtgac gatggggaat
     6781 catacgtggg acaaccgcgg aatctttgag tttgtaaatg aagctaaaaa gatggttcgt
     6841 ccggcaaatt ttccggaagg gacgcctgga caagggatgg tctttgtcaa agtgaaccaa
     6901 gtcgaactgg cagtgatcaa catgcaggct cgttctttta tggtggactt ggatgatcct
     6961 tttcgtaaaa tgaatgagct ggtagaagaa gccagaaaac gtacgccgat catttttgta
     7021 gattttcatg gagaaacaac aagtgaaaaa caagcaatgg gctggttttt agatgggaaa
     7081 gtttcagcag tggtcggtac acatacacac gttcagacaa atgatgcgcg aattttgcca
     7141 agaggaacag cgtatctgac agacgttggg atgacaggtc cctatgatgg tattttgggt
     7201 atgcgcagag aacctgtaat cgaaaagttt ctgactgcat taccaaaacg ttttgaagtt
     7261 gtggaacaag gccgatcgat tttaagcggc tgtatcttgg aattggatga tacgacaggt
     7321 catgcaaaag aaatccagct gattcagatc aacgatgatc gaccgttcat ggagtagaaa
     7381 gagaggcagt tttttgcagc aggagccgga aattcaaaaa gaagtaagga aactgacaaa
     7441 acttttaaga gagaatgaaa cgatcattcg ctacaaagaa cttgaagaaa agatccagca
     7501 aaaccagtat ttagctgagt tgagagaaaa aatcaaacaa gcgcaaaaag atgctgttca
     7561 ttttgcccac tatgacaaac cagcagcaga aaaagaagca atcaaacaag cggatcaatt
     7621 catgcaagaa tttgatcagc atccgcttgt tgtagcttat agaaaacagc tgttggaagc
     7681 agatgatctg cttcatcatt taacaactat gatacaagaa gaaatcaatg gacaaataga
     7741 ggaggaaaaa catgcctcaa aaaactaaaa atactcctat gatggaacaa tatctaagca
     7801 tcaaggccca ataccaagat gcttttttgt tctatcgttt aggagacttt tatgaactat
     7861 tttacgaaga tgcgatcaaa gcgtcacagc ttttggaatt aacgttgacg agcagaaatc
     7921 gaaatgcaga agaacctatt cctatgtgcg gtgtacctca ccatgcagca caaggatata
     7981 tcgatgcctt gattgaaaaa ggctataaag tagcgatttg cgagcaggta gaagatccaa
     8041 agacgactaa agggatggtc aagcgcgaag tgatccagct agtcactcct ggtacagtca
     8101 tggacagcaa aggattgtcg gcaaaagaca acaatttttt aacagctgta gttagtcaag
     8161 gaaatgaatt tggctttgct tatgccgatt taagtacggg agaattgaag acggctcggt
     8221 tgcatgatga agaagctgtt ttaaatgaag cctctgcatt gcagacaaaa gaactcgtat
     8281 taggcagtga gatcactgat acccttcgtg aacagctaag cgggcgttta gggctagtct
     8341 tttctcaaca aaatgagatg gaagaaaacg cggaatttag ctttttgaca agcgaactag
     8401 tcgatccgct ggaaaaagaa gcaaccggca aactattgac ttatttatcg gtgacacaaa
     8461 agcggagttt agctcatatc caaaaagcag tagaatacca accagatcat tttttgaaaa
     8521 tggattatta ttcaaaattc aacctagaat taagccaatc tattcggact gggaaaaagc
     8581 acggcactct tctatggttg ttagatgaaa caaaaacagc aatgggtggc cgtttactaa
     8641 aacaatggct agaccgtccg cttatccagg caaaacaaat taaagcaaga caagaaatgg
     8701 tcgcttcttt gctagacagc tattttgaac gtatcgattt gcagtcagca ttaacgaaag
     8761 tctatgatct ggaacgccta gcaggtcgag tagctttcgg taatgtcaat gggcgagact
     8821 tgatccagct gaaaacttct ttagaacaag tgccaatgat cagagggttg attgaaggaa
     8881 tcgatcaagg tcaatggcaa agtctgcttt cagaaatgca gccgatggac catctcgtcc
     8941 aattgatcga ccaagctatc caagatgatc cgccgttaca aataacggaa ggaaacatca
     9001 tcaaagatgg attcaatgag cagctcgata tgtaccgttc tgctatgaga aacggaaaga
     9061 aatggttggc agaacttgaa gcaaaagagc gtcaagaaac aggaatcaag aacttaaaaa
     9121 tcggatttaa ccgcgttttc ggttattata tagaaattac aaaagcaaat cttggaaatg
     9181 cagaactgga gaagtatgaa cgaaaacaaa ctttagcaaa tgcagagcgt ttcatcacac
     9241 cagaactaaa agaattggag acacaaatcc tcgaagcaga agaaaaatct gttgatttag
     9301 aatatcagtt gtttttagct gtgagagaag aagtcaaaaa ggctatccag ccgctacaag
     9361 tacttgcaaa agcaatcagt gcagtagatg tgctacaaag ttttgcaacg atcagcgaac
     9421 gctatcagta tgttcggcca gaacttgtca gtgacaagca tcagcttctg atcaaagacg
     9481 gacgacatcc tgtagtagaa aaagtattag gacatcagga atatatccct aacagcgtag
     9541 aaatggcaga agacgaaatg atcttgctga ttacaggacc gaatatgtct ggtaaaagta
     9601 cgtatatgcg acagttggca ttaactgttc tgatggcgca aatgggctgt ttcgttccgg
     9661 caaaacaagc agttttacct atttttgatc ggatttttac ccgaattggt gcaagtgacg
     9721 acttaattgc tggacaaagt acttttatgg tagagatgat ggaagccaat caagccctgc
     9781 gttatgctac gccaaacagt ttgattttgt ttgacgaact agggcgagga acagcaacct
     9841 atgacggaat ggcgttggcc caagcaatca tcgaatatat ccatcgtcat gtacaagcaa
     9901 aaacactctt ttctactcat tatcatgaac tgacggtact tgagaaagaa cttccgcagc
     9961 ttaaaaatgt ccatgttgga gccgttgaaa aagacggaga agttgtcttc ttgcataaaa
    10021 tgatggatgg acctgcggat aaaagctacg gcatacatgt ggcaaagatc gcaggattgc
    10081 cttccaatct actagaacga gcagcagata tcctgcatac gctagaaaat ggcgataacg
    10141 gacaccatac tgttccagct gaagtagaag agaaaactaa aacagccaaa caggagcaaa
    10201 taaaaccacc tgcagaaaaa gtaaatcaag accatataca agaccgtgta aaagaagaaa
    10261 accaacagct ttctttattc agtgaattat ccgaaaatga aacagaagtc attgaatcac
    10321 tgaagcaaat aaatttacta gaaatgacgc caatggatgc actaaacaca ttatatgaat
    10381 tacaaaaaca actgtaggaa gaaggcggat atcgatggcc aaaatccaag aattatctga
    10441 acgtttagct aatcagatcg ctgcgggaga agtagtggag cgaccagctt ccgttgtgaa
    10501 agaattagtg gaaaatgcaa ttgacgccgg cagtactcag attgatatct tagttgaaga
    10561 agcgggactg cggacgatcc aagtgattga taacggagaa ggcattttgg cagacgacgt
    10621 agagaatgcc ttcaagcggc atgcgacaag taagatccat aatcgcgacg atctttttcg
    10681 catacgaacg ctgggctttc gaggggaagc tttgccaagt attgcctctg tttctgaaat
    10741 gactctggaa acggcgaatc aggaagaaaa acaaggcacc tatctgtcgc tgaaaggcgg
    10801 agaagttatt gagcatcgac cagcaccact gcgtcaagga acgaagatta ccgtcagcaa
    10861 tctgtttttc aatacgccag cccgcttgaa atacgtgaaa acactgcaca cagaattagc
    10921 gaacatcggg gacatcgtca atcgactggc attgagtcat ccatcgattg cttttcgttt
    10981 agtacatgat ggaaacaaaa tgctggcaac tgctggaaat ggcgatctga aacaaacaat
    11041 tgcgggaatc tacggattat ctaccgcaaa aaaaatgctg aaaatcgaag gaaaagatct
    11101 agattttgag ttatttggct atgtttcatt gcctgaggtg actcgtgcca gtaggaatta
    11161 cttatcgacg atcatcaatg gacgttttat caagaacttt tccttgaata aagcaatcgt
    11221 tgcaggttat gggtcaaaat taatggtcgg tcgtttccct attgctgtat tggaaatcaa
    11281 aatggacccg cttttagtag atgtaaatgt tcatccgacg aagcaggaag tccggctgtc
    11341 gaaggaaaaa gaactaacag agctaattag taacgccatt caaaaagcat tgtctcaaga
    11401 aaatctgatt ccaagtgcag cggataatct acggtttaag aaaaaagtac ctgatcagcc
    11461 taaaacagaa caaatcgaaa tcgatttgtc ctacgctttt gaagaagaaa aacctaaaaa
    11521 gccaagtagt ttgaattttg atcgacagac aggtaccttt ttcgtagaag aactaaagaa
    11581 cacatttgtt gacagaattg ttgataagtc tgtggaaaat gttgaaaact attctggttt
    11641 ttctgaagaa aacaccactt atccagaaaa aacagcgaaa acggtggata agtttggtga
    11701 aaatgttgat aactttgtag aaaaaacagt ggaaaaatct gaaaagaaag aatttcccat
    11761 tgtggataac atggagaaaa caaatgaaga acaagcagat aaatccgtag aagaggatga
    11821 aaagatttac gaggaagaat tgacactcca tcctgaattt gatttcactc aaggaaacga
    11881 caaaacatta gaacaagcca tcaagaaatt agaaacggaa aaaccagtac aacgttttcc
    11941 tcagttggaa tattttggac agatgcacgg aacgtatctt tttgcccaaa gtagcgatgg
    12001 gttgtacatc attgatcagc atgctgccca agagcgcatt aagtatgaat atttccggga
    12061 aaaaattggg gaagtatctg atgatctgca agaattgctt gttccatttg tgttagacta
    12121 tccaaacagt gatgctttga aattaaaaga gcaaaaacac ttgctagaag atgcagggat
    12181 ttatttagaa gaatttggtc aaaacagctt tattgtacgg gcccatccta cttggtatcc
    12241 caatggagaa gaagaatcga ttattcggga gatgatcgat atgctgctga caactggaag
    12301 tgtgagtgta aaaaaattcc gtgaagcaac agcaatcatg atgagttgca aacgatcgat
    12361 taaagccaac cattatttga atgaagcaca agcacgtgtg ctgctgaagg atctggcacg
    12421 atgcgaaaat cctttcaatt gtccccatgg ccgtccagta ttgattcact ttaccaattc
    12481 ggatatggaa aggatgttca aacgaatcca agacccgcat taagtcaaag agaagaggga
    12541 aaacatgaag attgtattag catcccaatc accaagaaga aaagagttat tggctcatat
    12601 cgtttcagaa ttcgagattg aacctgctga tatcgatgaa acgccatttc cagacgaaca
    12661 gcccgtcgat tatgttcgta gaatggctga agaaaaagca cgaactgtct gggaacaaga
    12721 tgaaaaagaa gaccatttag tgattgccag tgacacgact gttgttctca atcaagagat
    12781 catgggtaaa ccagaagatc tggctgaggc tgaattcatg ctgaaaaaac taagcgggga
    12841 aacacatact gtatatacag ctgttgtttt aaaaacaaag gaacgagaag aacggatact
    12901 agcagaagca catgtcactt tttatccttt gacagacgaa gagatcaaac gctacttgga
    12961 gacgggggat tatgcggata aggcaggggc atacggcatc caaaatgctg cgagtgtatt
    13021 cgtcaaagaa atttctggag attattacag tatcgtagga tttccgattg gtgctgtcaa
    13081 tcaggcactg aaaacattca tttaaacaaa aaagcggact atctgatttt cgattgaaaa
    13141 tccatgatag cccgtttttt ttattgaaaa gattacttat ctactctgac taagatttta
    13201 cttcagcttt accgactgct tcgcccgggc gaacaagtcc tgattggtca agagaaagtc
    13261 ctgcaacttt ttcattattg gtcaaagcaa caataatgtc agttttcttg ccagcttgtt
    13321 ctatttctgg caaatccatt tcagcaatca gggtctctgg tgtgacaagg tatccttctt
    13381 tcacgaatac attgaaagga acacccttta gttcaacagt atctaatccc atgtgaacaa
    13441 gtacttccag cccctcatta gaaagaatac caatggcatg ttttgtttca aagacactcg
    13501 tcactttacc gtttactggt gcatagactt tgccgtttga cggttcgaca gcataaccgt
    13561 cacccatcat tttttgtgag aaaactgggt catttacttc agttatttcc ttgatggtcc
    13621 ctgcagcgac tgcgaataat gtttcttttg ttgcaactgc cgtaccagtt gctgaaacag
    13681 gttcgaaaga ctgtggcgtt gctgttgcgc catttgctgt ttgaagttgt acatcagcag
    13741 cattttcagg aacagcagga tcaatcttat tcaaaattcc ctgacgtcta aagatgatcg
    13801 tcaagccaaa tggaatgatg acagcaatga tcattgcgat gatgaaaggt acccatgttt
    13861 ctgcttggat agctagtatt cctggcaaac cgcctactcc gatcgcgtta gctcgaacac
    13921 ccatcaagtt agcaaacatg ccagctaatc cagagccgac cattgcagcg acgaaaggat
    13981 agacgtattt caaattgatt ccgaacatag caggttcagt tacgcctaag taacaagaaa
    14041 tcattgctgg aatcgagatt tgttcttctt ttttattccc acgatgtaag aagatgatgg
    14101 ctaagactgc agagccttgg gcgatatttg ataaagcaat catcggccat aaattcgttg
    14161 atccgaaatc tgcaatcagc tgcatatcga tggcattggt catatggtgg agaccagtaa
    14221 tcactaaagg agcatacagg aatccgaata cggcactaaa caaccagctg atagaagacg
    14281 tcaatccagt atttacgata tttgagatcc agcttccgac tgtccagccg ataggaccta
    14341 aaataacgtg tgcagctaaa acagttggta acaatgaaaa caatggaaca aaaatcatcg
    14401 agatcgactg agggatatat ttgcggaaga agatttctag atacgctaac ataaaccctg
    14461 ccagcatggc tggaataact tgcgcttgat aaccaatcat ctggacttga gcaaaaccaa
    14521 aatcccaaaa tggaatatct gctgcggctg tggaagctac actataagca tttaataatt
    14581 gcggagaaac taacgtaatt cctaaaacga ttcctaatat ttgtgtagta cccatctttt
    14641 ttgcaatact ccaagtgata cctactggaa gaaaatggaa aattgcttca ccgggtaacc
    14701 acaaaaaggc attgacacca ttccaaaact tcgagtgttc aacgattgtt ccaccaagac
    14761 tttcaaactg gataccttca agtacatttc tgaatccaag gatcaatcca ccgacaatga
    14821 ttgcaggaat cagtggtgta aagatttctg ctaaaacggc aatagcacgt tgaacgggat
    14881 gaaggttttg ttttgcagct gcttttcctt gttctttgga aaccccttca actccagata
    14941 ctgcaacgaa gtcgttataa aaagtagaaa catcgtttcc tatgatgact tggaactgtc
    15001 ctgcattcgt gaacatccct tttacgctag gtatatcttc gatcgctttt tcgtccgctt
    15061 ttcctggatc attcaggaca aaacgcatac gagtcgcaca atgactaact gcagcaatat
    15121 tttcttttcc gccgatatca tgtaacagct tctcggcatc tgcttgatat tttgccatat
    15181 caataaaccc ctttctctta acttgtctat gcaagttgtt tcttcattta ctatactttt
    15241 tttcggagag aattgcaagc gttttattaa aaagtacgag agaaaatgat atcgttttaa
    15301 aaagcttaaa ataagctttt cttaaaaata ggaacattga aatacaaaaa gagctgtagt
    15361 atagtgaaga aatgatggaa gaacgagtga gggaaaaaac atgaataagt tcaatgaaat
    15421 ttttttagat ttggaacaga aaattttagc gaaagaatat cctccgcatt cgcttttacc
    15481 cagtgagaac caattgatca aaatttatgg tgtttcacga gaaacaatta gaaaagcgct
    15541 gaatcttttg actacggaag gttatattca aaaaaaacaa ggaaaaggtt cgatcgtact
    15601 ggatcggaat cgcttcgact ttcctatttc tggattgact agctataaag agctacagga
    15661 gacccaacgt attccaagtg aaacgatcat ccatacgtta gaagaaacag aagtgacaaa
    15721 agcattgaac gagatcactg gctgggagat cggtgcgcct gtttggcatt tgatacgcga
    15781 aagaaaaatc aatggcgaag tagttatatt agacaccgat tatctattaa aggaaatcgt
    15841 tcctatttta actccagcac aagcacaagg atcgatctat gaatattttg aaaatgagct
    15901 ttctttgacg attgcttacg cgcaaaagga gatcacagta gaagaagtaa cggaaatcat
    15961 gaaaacagcg atggatcttc acgatgacac ttatgcagta gtagtcagaa gcctcgttca
    16021 tctggaagat acccgctgtt tcgagtattc tgagtcggtt caccgattag ataaattccg
    16081 tttcgttgag tttgcccgac gccgaaaagt gtaaatagtt caaaagaaag caaattgttg
    16141 gcatctgtcc actttggcgc tatgatagga tcacaaaggg ggcattttta atggataaac
    16201 caataagacc agaaaaagaa gaactgaaag aaaagttatc acccatggct tatgcagtca
    16261 cacaagaaaa tgcaacagaa cgaccattta gcgggaaata tgatgatttt tacgaaaagg
    16321 ggatctatgt agatatcgtc agcggtgaac cgttattcag ctctgcagaa aaatatgatg
    16381 caggttgtgg ctggccatca ttcagcaaac caataacgaa aagacaagtg cgcgaaaaag
    16441 ccgatttttc tcatggcatg catcgaatag aagttcgaag caaagaagca gattctcatc
    16501 tcggacatgt gtttaccgat ggaccagtag atcaaggtgg tctacgttac tgcatcaatt
    16561 ctgcctcact gaaattcatt ccatatgaaa agatggatga attaggttat ggggaattca
    16621 aatcacttgt agaataatgg aaatacacaa agagcggtac aatacgggga tttactcgat
    16681 cgtccgctct ttttttattc aagcgattgc tatttgaaag aaacgctccc tagactcctt
    16741 tttttcacaa ggtgaaatgt gctacaataa agggaacgta tgtgtgcaaa agaaagagga
    16801 ctagaatatg tatgaatatc tgacaggtgt ggttaccttt atcaacccct attacatagt
    16861 agtagaaacc aatggtatcg gctaccagat cgcactagga aatccttacc gctacagtag
    16921 caaactaaat caaaaaataa aaatttatgt ccatcaggta atacgtgaag atgcgcatct
    16981 tctgtatgga tttgattcgc tagaagaaaa gcaactgttt ttgcgattag taagtgtttc
    17041 aggaatcggt ccgaaaagtg cccttgcaat catggcaagc gaagaccact ccggtttgat
    17101 tcaagcagta gaatccagtg atgtcactta tttgacgaaa tttccaggag tagggaaaaa
    17161 gacagcacaa caaatgatct tggatctaaa aggaaaattc ggtgagctga gtatcgatac
    17221 accttttagt ctatttgatg aagcaaacac aaaagacgct acagctctat ctgaagcaat
    17281 ggaagctctc tcggctcttg gttacagtga tcgagaaatc aaacgtgtag aaaaacaatt
    17341 aaaagaagta gataatcaga caacggatga gtatctacgc caagcactca agctaatgat
    17401 gaaaaaataa ggaggagacc aaatgacaga tgaatacttg ttatcaccag aatctggcga
    17461 aaatgaactg agtttggaaa aatctcttcg accacagctg ctttctcaat atatcggaca
    17521 gagaaaagtc aaacaagaac ttcagattta catcgaagct gccagaaatc gggaagaacc
    17581 tttagatcat gttctgttgt acgggcctcc tggattagga aaaacgacga tggccatggt
    17641 cattgctaat gagatgaccg taaatattcg tacgacgagt ggccctgcta tcgaacgtcc
    17701 gggtgactta gtagcaatct tgaatgaact ggaagcaggg gatgtcctgt ttatcgatga
    17761 gatccatcga ttacctagag tggtagaaga gatgctttat tcagctatgg aagatttcta
    17821 tgtagatatc atggtaggac aagggccaac cgcacatccg gttcatttcc ctcttcctcc
    17881 ctttactttg attggcgcga cgacacgggc aggtatgctt tctgcacctt tacgagatcg
    17941 atttggcatc atttctcata tggaatatta tgacgaacag gatctgcagg agatcgtttt
    18001 acgttcttcg gatatttttc aaacagagat cattgaagaa ggggcattgg aaattgctcg
    18061 ccgatcacga ggaacgccta gaatcgctaa tcgcttgctc aaacgggttc gtgattttgc
    18121 gcaagtccaa ggagacggga aaatcgatcg tcctatagcg gatcaggcac ttactttgct
    18181 acaggtcgat caggctggat tggattatgt tgaccagaaa ttgttgcgaa caatgatcga
    18241 gttatatggc ggcggaccag tagggttaag tacgctttca gtaaacatag gagaagagcg
    18301 tgagacggta gaagatatgt atgaaccgta tctgatccaa aaaggatttt taaagcgtac
    18361 acctagaggg cgaattgcta ctgcttatgc ctatgaacat tttggttacg actatcatat
    18421 atgatttttg cttttagatt ggaggaaaat gaatgagtga tacaacacgt acgaaacaat
    18481 tgatcaaaaa cgtattgatt gatttgtgcc aaacgcaatc ttttcgaaaa atcagcgtcc
    18541 aaaaaatcgc aaacgaagca aaaatcaatc gacaaacatt ttattatcat tttacagata
    18601 aatacgattt gcttcgttgg gtctattgtg aggatgcatt gcattattta gatccacaat
    18661 gtctttcact tgataattgg gaagagcaag cattgaaaat gctgaaagca attgctgaga
    18721 agaaagaatt ttatgcaaat actgtgcttt ctgacccaga aattttacaa aaagagtttt
    18781 ctcaactgat ccaaaaatca tttatcaaga tttttgaaca aatggatgaa gaaagacaac
    18841 tttctgcaag agacaaacta ttttatgctc gttttttttc ttacggttgc agtggtgtat
    18901 tagtcaattg gatcacgaat gaatatgaag aaacaccgat ggaaatcgct atgcagcttt
    18961 tccgtttagc caaggatacg gaattatatt cttatcgtct ttatgcaaaa gaagagttgg
    19021 aagaacagta atagaaaaat tttttgttgg aaaagcaata atcgctaaaa ggagatgggg
    19081 aaatgacaaa aattttattt gtttgtttgg gaaatatttg ccgttcaccg atggcagaag
    19141 gcttgctgag aaaacgaata gcattagaag gaagggaagc agaatttttt gtggattctg
    19201 ctgctacaag cacgtatgaa gttggaaaga caccgcaccc tggaacgaaa aaaatattaa
    19261 accaagaaaa agtagatatg acgaatatgg ttgctcggca aatcacaccc cacgattttg
    19321 aaacttttga ttggatcatt ggcatggatc aagaaaatgt agaagaactg aaacgaagag
    19381 caccacgctc agcgcagggg aaaatccatt tgtttttaag tagcattcct ggaaaagaaa
    19441 aagaaaatgt tcccgaccca tactatacca ataactttga tgagacatat cacttgatca
    19501 cagaaggcct gaatcattgg tggaatattt ggattgatga aaataaaata acaaacaatt
    19561 tgtaaagtta acgctttctt tttaaggcga tgttagagca tttccttgtt tttttgtaaa
    19621 atgttaggta aaataaaatt aattaagtaa cactttctta gctaaaggag gagtgcattc
    19681 gatgaacgaa gagacagtat cgccaatgaa gaagcttacg aagttagtta ctcatacttc
    19741 gtatcaactt tttgattctt ttgtaaatga cactgaagaa catgctaaga atgtacgatt
    19801 gcaaggaaag tttattcttg agctgcaaaa agctgctact gaacatagtc tagttatctt
    19861 acaagtaaga gcaaatcgtt tgagtagcaa gtatgaaacg atctcaggct gggtggcgac
    19921 aaaaacggtc gaaaaagacc gagtgatgat ccgcctacaa aacgaagagc agcagatccg
    19981 gatggttcct gtagaacaaa ttgaaaaaat aacaatcctt tcaccagcag gggaacagga
    20041 acggttatca aaataattta taccagatag aaaagcacgt atgagcttgt accatcaatc
    20101 attactaatc aaaaataacc gaatgcttta agctgatatc agtaaaacgg aacgttttag
    20161 gatgagtatc atagcatgac agcattcggt tgattagttg aatcgattgg atggtacaag
    20221 tttttttgat aaaaaaaggt cctgctagcc ggggagctag caggataagg agttaaaaat
    20281 gaaaaagtgt tgttagggtt gtttgttggt atgcttatat aatagtcatt agttgtgaat
    20341 attttgtgac gaaagttttc gaaagttgtt aag
//
LOCUS       DADGHT010000051        20128 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.051, whole genome shotgun sequence.
ACCESSION   DADGHT010000051 DADGHT010000000
VERSION     DADGHT010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20128
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.051"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            133..636
                     /locus_tag="JX887_001653"
     CDS             133..636
                     /locus_tag="JX887_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAX1257644.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            763..1800
                     /locus_tag="JX887_001654"
     CDS             763..1800
                     /locus_tag="JX887_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257645.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            1815..3512
                     /locus_tag="JX887_001655"
     CDS             1815..3512
                     /locus_tag="JX887_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HAX1257646.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKIPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            3505..3966
                     /locus_tag="JX887_001656"
     CDS             3505..3966
                     /locus_tag="JX887_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257647.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            3979..4839
                     /locus_tag="JX887_001657"
     CDS             3979..4839
                     /locus_tag="JX887_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257648.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFFGRSRRFKLYVLQKDYASNG
                     KYSKKYRIFI"
     gene            4877..5266
                     /locus_tag="JX887_001658"
     CDS             4877..5266
                     /locus_tag="JX887_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1257649.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            5253..7700
                     /locus_tag="JX887_001659"
     CDS             5253..7700
                     /locus_tag="JX887_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1257650.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSMI
                     GDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            7705..9813
                     /locus_tag="JX887_001660"
     CDS             7705..9813
                     /locus_tag="JX887_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAX1257651.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            9810..10814
                     /locus_tag="JX887_001661"
     CDS             9810..10814
                     /locus_tag="JX887_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAX1257652.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            10833..11744
                     /locus_tag="JX887_001662"
     CDS             10833..11744
                     /locus_tag="JX887_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1257653.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
     gene            11931..12218
                     /locus_tag="JX887_001663"
                     /pseudo
     CDS             11931..12218
                     /locus_tag="JX887_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(12406..12621)
                     /locus_tag="JX887_001664"
     CDS             complement(12406..12621)
                     /locus_tag="JX887_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257654.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(12880..13047)
                     /locus_tag="JX887_001665"
     CDS             complement(12880..13047)
                     /locus_tag="JX887_001665"
                     /inference="COORDINATES: protein motif:HMM:NF018933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1257655.1"
                     /translation="MGSECGHTDGKKSFTIREWTCPICRTHHDRNVNVSINILIKGYV
                     YKHCLRKHQEP"
     gene            complement(13392..14831)
                     /locus_tag="JX887_001666"
                     /pseudo
     CDS             complement(13392..14831)
                     /locus_tag="JX887_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(15379..16050)
                     /locus_tag="JX887_001667"
     CDS             complement(15379..16050)
                     /locus_tag="JX887_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAX1257656.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
     gene            complement(16399..17850)
                     /locus_tag="JX887_001668"
     CDS             complement(16399..17850)
                     /locus_tag="JX887_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAX1257657.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            complement(17962..19305)
                     /locus_tag="JX887_001669"
     CDS             complement(17962..19305)
                     /locus_tag="JX887_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAX1257658.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLEDLFYQNRRELNSKIKKLFLETAVDKIDIQNKKIICVKKDGTRFSQ
                     EYDKLILATGSKQIMLDVPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGKKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHIDNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPVFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            complement(19439..>20128)
                     /locus_tag="JX887_001670"
     CDS             complement(19439..>20128)
                     /locus_tag="JX887_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAX1257659.1"
                     /translation="NPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTA
                     GNKKGIVVVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTV
                     TLPNGSQYHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNEKDSE
                     KAVSKDNKTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILLGTLGL
                     LGYKNRKKENE"
BASE COUNT         6498 a         3414 c         3743 g         6473 t
ORIGIN      
        1 gagttttcca aactgattgg cttcttggtg attgctttga ttgcggtagg tctggtcttt
       61 aatgcttctg gtgtgaagga tgtcctactc aatttgttta accgaattgt cggtgcctga
      121 gggggaatca caatggaaca gatgcgtgtt tatattgcga accttggaaa atacaatgaa
      181 ggtgagttgg tgggggcatg gtttacccca cctgtcgatt ttgatgaagt gaaagaacag
      241 attggattaa atgacgaata tgaagagtac gcgattcatg attatgaact gccttttgag
      301 attgatgagt atacgccaat tgaagagatt aatcggttgt gtaacttagc ggaggaacta
      361 gaaggaacgc caattggtga agctgcttct gagattcaac acgctttctt caattctttc
      421 gaggaaatgg tagagcatgt ggatgatatt gtctattatc cagattgcga tgatatgagt
      481 gatgtggcgc attacttgat tgtagaagct ggtgattttg gcgaagttcc agaacaattg
      541 aagccgtata ttgattttga tgcttgcggt cgagatttgg agattggagg aaattatttg
      601 gttactagtc gtggagtttt tgagtatcca gaatgaatca aacactatat atagtgtttg
      661 attagtatat gtaagcaaaa aaacacaata tatagagtgc aaactgaagg gtaatgtgat
      721 ataatatttg ccgaagaaat atttttgaaa tgaggtaata ttatggcaaa tattcaaaca
      781 agttttattg atttccataa ttcaattaga ttggacgtag aagacaatac gctacttaag
      841 gactataaag accaagtaat tgatggatta aaagattact tacctgatga tgtgaagttt
      901 gaaacttttt tacagggaag ctattctgtt tataccggaa taaaaagctg tgatgaaaaa
      961 attgattttg acatcgatat tgcagttgct ttcgaaattg atcatactgt ttatgaagat
     1021 ccaagggagc ctaaactgtg ggtaaaagag gcgctagttg aaatttttcc taatgctcaa
     1081 gttaatttaa aagtaccttg tgtaactgct acatttactg gaaaaaagac aaaaaaaaat
     1141 gtgcacgttg atgttgcggt ttatgctaaa gaagatgaaa attatttctt agcaaaagca
     1201 aaagaattca gtgctcccga aaaccgatgc tgggaggaag cggatcccaa agtattaaaa
     1261 gagaaaatta atagtcatgt agcagattca gatgatcgaa aacaatttcg aagatgtatt
     1321 cgctatttaa aaagatggaa agataacaat tttaaccaag aatataaacc aacaggaatt
     1381 ggacttacaa ttaatgtgat ggatacgttc ctagttaata agtccactga ttttttaact
     1441 agaaaagttc agtataatga tatggaatgt atgaagcaga ttgtttcttc gctgaaagat
     1501 tcatttgtgt atgagtacag tgaaacagat ggttggcatt atcgtctaca tgcatatctt
     1561 ccagtgaagc ctaacagtga cacctattca aaaatgacag tgaatcagat gagtgatttt
     1621 aaaaacaaac tttctaaatt atatgatgat ttgattttcg ctatcgatac tgaagatgag
     1681 tatgaagcta caaaacgatt aaataatcaa tttggggagg attttttaat tatttcagaa
     1741 gaagaagtta cagaaaaaaa cttaagaaat gcatttgtta cagactatcc gagtgcttag
     1801 gttggtgtta aagattggat tatactgata ttttaaaaga aaagctaaca gatgttgtgc
     1861 gtttattcga tggtaattac tatggggatt tttcatttgc tacaattgga aagttgcgtt
     1921 taaaaattga aataccaaaa cattttccat tggtacttcc taggatttac attcataatt
     1981 ttgatcattt aggactttac ctaccacatg tagaaaaaga tgggttggta tgtttttctt
     2041 cagatataaa ttatttagta gatgaagaaa attcagaatt ggttttattg cagtgtgtta
     2101 ataaaactat aaaaacaatt gaggaaggtt tgaaagggtt aaataaaaat gattttcgaa
     2161 aagagtttgt tgctttttgg gacaaacaag agaatcaaat ttcgttattc tacctttgtg
     2221 aaccagcgtt gtttatcaag tcagttgata caataatgta cggtaagtct ttggttgctt
     2281 tggataaaga gaacgaatta caattaaatg cagcgagtag attgtttaat ggagagaaag
     2341 aagatactca tgaattagat gcatactatg ttccaattag aaacaagaat aatattatgc
     2401 ccccgaagaa taataaagca tggtcaaaga aggatatttt acaaatagta aaaaaaaatg
     2461 taacaggtgc aaataaaaga ttttttttaa aacttgaaaa aagaaagaat agacataatg
     2521 ttttacttat tctagatatc ccaattgaag aaaagtcaaa taatgtcata attggatttc
     2581 tttttacaaa acaatctgga tctataaaag attataaggg tacgcctagg actgtattag
     2641 ttcagcgtca tgatgaatta tatttggtga atagaacgag cggagaaaac tatggattgg
     2701 gtgctaatat agctattgtt ggggtagggt cagttggcag taaaattgct gaaaatcttg
     2761 gtccattagg tgtgagaaag atgacactca tagacaatga ttgttttcaa gctgaaaatt
     2821 tgtatcgaaa ttcacttggt gcagatagtt taaaaaatgc ccgatctcag aataattttt
     2881 ttaaagttga tttaatgcag gaggagctcg aaaaaaaaat cccatacctt tgtgttgaag
     2941 tggagtcaat gaacgtttta gacttaatta gtatgcaacc tggttttttc aaggaatatg
     3001 actatgtttt tgtttgcata ggagatacaa tggcaagcct ggctttaaat aattattttt
     3061 ccaaaagtag tcaaaaagtt ttctattctt ggctggagcc atatggcatt gggggacaca
     3121 ctctatttat aaattattct ctaaatcaaa aaggttgttt caattgtctt tatacagatt
     3181 caaactctaa aaataggtgt tcaaatagag cttctctggt aaaagaagga caaatttttg
     3241 aaaggacttt agcgagttgc cgctcaaaat ttataccata taatgctatt gcctcgacgg
     3301 aatgtgcaat taatgcaata aaacttttcc ataaagtcaa tcaaaataat atgaccaata
     3361 gtactctttt ttcatggata ggagatggga gtacttttga gaatttagga tatcaatata
     3421 gcgacagaaa tacttttctt aatggagtca ataagtttga agaaagattc ttttctaaat
     3481 attgcaaagt atgtggggag ttagatgatt aaattttcgt gtgaccgtat tgtcattgaa
     3541 gtaagggatg aagttcttaa gatatttgaa caatatcggc agggaaagga tgacttgcct
     3601 gaagctggag gagttcttca tggaaaaaga cttaagaatg ggagcataat aattaccgat
     3661 ataacaacac ctcaaatagg agatatacaa aaaagattac tctttaaaaa aaaccgagaa
     3721 attcatcaac agctttctaa tgagaaatgg atagaatcaa ataagttttc tattgcattg
     3781 ggagaatggc atactcatcc tgaagctgta ccaactccat caaatgttga taagaaaagc
     3841 tggagactga acgtgagcaa gcaacatgat gatagagttt atgtttttat tatcgttgga
     3901 ttttctgatt tgagaatgtg gttactgtca aaaaaatcag atattaggca ggctataaaa
     3961 ctataaagga gtgattaggt gaaatcacaa aagaatattt ggtggtgggg gtttttagta
     4021 ggaaaggtaa tgataccagc ccttctctta atttctctac cgatgattac ttttttcttt
     4081 accaataaaa aaatgagtaa agaagccgtg atttttttct ttggagacca aaaagctacc
     4141 tttattgaaa cgttagtaac atctcttcag cttaatttga attacatttt ttcaattatt
     4201 attgttatat cgttattgaa tttttttaaa aaaagaaatt caggaaaggt gtttaactct
     4261 aatggaaatg tgtactacaa ctatttttat tttgtatttt gggtagcagc aactttactt
     4321 ggttatgata aaattcagat tgcaggaatt cctatacaca tgcaatataa gttggttttg
     4381 agtggaattt tttctgaggt gttgccagat atatacgatg atcattacga cagtgatgga
     4441 acatgtaaag taagcattga aaaagaaaat ttcgatgaca tcgatggata tgactctgtg
     4501 aacttactga ttattgatac ttacgatata aaaatgagtg aattatctat ggaaaatcaa
     4561 acatatccta cgataattgt tagagggaat tcaatagatg gagttcgtaa agttaataga
     4621 tctttaatct tggaaataaa aaaaacaatg gatgaaattc aaaaaagtga ctttaaaaaa
     4681 gtatttgttg cttcaacatc taatccaaaa aatagtatca atattattaa ttcatcgttt
     4741 agatttttcg gtcgatcacg taggtttaaa ctttatgttc ttcaaaagga ttatgcaagc
     4801 aatggaaagt atagtaagaa atatagaatt tttatttaag aaggaatttt tccttctttt
     4861 tattttggag gaaactatga aaaaaataaa aagctacacc agtatttggg cagttgaaaa
     4921 agtcatttat gcgattaatg actttcagct gccttttcct gtgaccttta accagatggc
     4981 ttggtttgtt ttatccttga tgtttgtcat tgtatttgcc catgtgcctc cgctatccat
     5041 gatagagggg gcttttttaa aatacttggg cattccgata gcggtcactt ggttcatgtc
     5101 gcaaaagacc tttgacggta agaaaccatt gggattttta cgatccttta tcagctatca
     5161 cttacggttt aaggtcactt ttgcaggaaa gaaagttaaa gaacagaaga aacgatggga
     5221 cgaaccaatc accttggtaa ggagtgtgaa ttatgtaccc gattaagtat attgaaaata
     5281 atcttgtctt taaccaagaa ggcgagtgtt ttgcttacta tgaattagtg ccttacaatt
     5341 actccttttt gtcacctgaa cagaagtatc aagtacatga taactttcgc caattaattg
     5401 cgcaaaatcg tgaaggtaag atccatgcct tacaaattgc cacagaaagt agtattcgtg
     5461 ccacacaaga acgttcgaaa aaggaaatta ccggtagact caaagaagta gcaaagcaac
     5521 gaattgattt acagacagat gcattagtat ccatgattgg cgatagtcag attgattatc
     5581 gcttctttat tggctttaaa ctgatttcga cagatgaaga ggtcaatcta aagaatctca
     5641 ggaaatcttt cttttctgga cttcaagaat ttgtctatgg agtgaatcat catttgatgg
     5701 gtgattttgt ttccttatcc aatgaagaaa ttcgtcgcta taccaagctt gaaaaactaa
     5761 tggaaagtaa attggctcga agatttaaag tcaaacgagt aacgccgagt gacttgacgt
     5821 atttaattga acatatctat ggtgaaaaag gcacaccgtt tgaagaatat gaattccagc
     5881 taccaaagaa aaagctgaaa tcagaaacgc tggtgaaacg ttacgactta ttacgtccca
     5941 ctcgttgttt gattgaagaa aagcctcggt acttacggat ggaacatgaa aatcatgagt
     6001 cttatgtagc gtacttaaca attaatacca ttgtagggga aatggagttt ccttcctcgg
     6061 aacttttcta ttaccagcaa caacaattta cgtttccgat tgatacttca atgaatgtgg
     6121 aaattgtgac gaataaaaag gccctagcta ccgttcgtaa taagaaaaag gaattaaaag
     6181 atttagacaa ccatgcctat caatctgata atgaaacgaa ctccaatgta ttagatgctt
     6241 tggattccgt ggatgaattg gaaaccacct tggatcagtc gaaagaatcc atgtataaac
     6301 taagctatgt ggttcgagtg agtgctaaat cagtggatga attaaaacgc cgctgtgatg
     6361 aagtgctcga tttttatgac gataccaatg taaaactagt ccggcccttt ggcgatatga
     6421 tgggtctaca caaagaattc ttaccctcaa gtaagcgata catgaatgac tatattcaat
     6481 atgttacgtc tgactttttg gcgggacttg gttttggggc tactcaaatg ctaggagaat
     6541 tagaaggcat ttactttggc tataacgtag atacggggcg caatgtttac ctgaaaccgg
     6601 cattggcatc acaaggggtc aaaggctcag taaccaatgc tttggcatct gctttccttg
     6661 gttcgttagg tggggggaaa tcttttagca acaatctctt agtctattat gccgtccttt
     6721 ttggtgggca agctgtgatt gtcgatccaa aaggagaaag aggcggttgg aaagaaacgt
     6781 tgccagaaat tgcggatgaa attaatattc ttaacttgac cagtaagcca gaaaatcaag
     6841 gcttacttga tccctatgtg attatgaaga aaaagaaaga ctcagaaagt ttggcgattg
     6901 atatcctgac ctttttaaca gggatttcca gtcgggatgg ggagaagttc cctgtgttac
     6961 gcaaagccat tcgaacggtt acccaaagtg atcagcgagg attattacaa gtaatcgttg
     7021 aattgcgtaa agaggactca ccagtcgcgg aaaatatcgc ggatcacatc gagtccttta
     7081 ccgattatga ttttgcccat ttgcttttct cagatggttc gattacccag tcgattagtt
     7141 tagataagca gttaaatatc attcaagtag cggatttggt tttaccagat gcagaaacca
     7201 cttttgaaga atataccacc atggaattgc tgagtgtttc catgctaatt gttatttcca
     7261 cttttgcctt ggactttatc catagcaacc gagaaatttt caagattgtg gacctggatg
     7321 aggcttggag ttttcttcaa gtagctcaag gaaaaacgtt atcgaataaa ttagtgcgtg
     7381 ctggtcgggc catgaatgcc ggtgtttact tcgtcacgca aaacagtgat gacttgttgg
     7441 atgaacgttt gaagaataat attgggctaa agtttgcatt tcgcagtacc gatattcatg
     7501 aaatcaagaa aaccttggaa ttctttggat tagataaaga agatgaaagt aatcaaaaat
     7561 gcatgcgaga tttggaaaat gggcaatgct tgatgcagga tttgtatggt cgagtaggtg
     7621 tggtccaagt tcatccagtc tttgaagaac ttttccatgc ttttgatacc cgtccgccag
     7681 ttcaagagag aatggagtga ggagatgaaa aagaaacttt ttcgtatctt tggaattgtt
     7741 ttaatcagtt tggtcactct gataatactt ttgagcttag ttggaacggt agctgaggca
     7801 acaggtctgg ttgatgatac agttggagcc ggaaatcttt attcccaata ttcacttggt
     7861 aactatcagt tggatttctt tgtggatagt tcgtgggatt ggctgccttg gaattggggt
     7921 gatggcctag ggaagagcgt aatgtatgga ctttatgcca ttactaattt tatttggaca
     7981 gttagtctct acttatcaaa tgccacgggc tacgtggttc aagaagccta taagctggat
     8041 ttcatttcag atacggctga aagtattggg aagaatatcc aaaccttagc cggcattacc
     8101 gaaaatggac tccagacctc gggcttttac tttgggtttc tattattgat gattttagct
     8161 ctaggagttt atgtggcgta tacaggatta ttaaaacgag aaactaccaa agcagtccgg
     8221 gctgtcatta attttgtgat gatttttcta ctttcgggtt cgttcattgc gtatgcgccc
     8281 acctatatca caaaaatcaa tgattttagc tcagatgtca gcgaagcggc tcttagcctt
     8341 ggaaccgaga ttgtcgtgcc gaattcagaa agccaaggaa aggacagtgt ggatttaatc
     8401 cgagatagct tgttttccat tcaagtccaa caaccgtggt tactcttgca atttgatgat
     8461 tccaatatag aagaagttgg cgaagatcgt gttaacaaaa tcctgtctgt aagtccagat
     8521 gaaaataaag gcaaggatcg ggaagaagcg gtcaaagcgg agattgaaga taatgacaat
     8581 gcgaatctca gtattaccaa gaccatgaac cgcttaggga ccgtggtctt tttggtgttg
     8641 ttcaatattg gcatatcctt ctttgtcttt ctcctaacag ggattatgtt gttctcgcaa
     8701 attctcttta ttatctttgc gatgtttttg ccgattagtt tcttattgtc catgttgccg
     8761 acttatgaga gtttgggcaa gaaggcgatt attcgcttgt tcaatacgat tatgatgcga
     8821 gcaggagtta ctttggtgat tacgactgca tttagcatct ccacgatgtt tttcaatatt
     8881 tcggcaacct atccattttt catggttgct tttctgcaaa ttgtgacctt tgccggtatc
     8941 tatttcaaat tgggcgacat tatgaatatg ttcaatctcc agagtaatga tagccaatca
     9001 atgggaagac gggtcatgcg aaaaccgcaa atgttaatga atcgaacatt gcggcaactc
     9061 aatcgaaatg tgggacggac tttggctttt ggtggtggtg cagcagttgg aaataagttg
     9121 gcaaaggaac aatcaaaatc caaatttaag ccatccggtt cttctctacg aaagaattca
     9181 cgattaccga acgatcacga gataccatct gacttgaata aggaaaagcc aattccaaat
     9241 aataagaaac aatcccgaat gaatttggcc gggagaaaag tcggcaaggt tctggatacc
     9301 caagctttgg tgaaagataa gaccaaacaa gtaaaggatg gagtacggaa tacgccaacc
     9361 aacttgaaat acaacttcca taaaggaatt gaaaaaacga aaaaagcacc ggaagagttt
     9421 aagcgaggac tggtccaaga aaaagcaaat cgaggagagt tgcgagaaaa acaacaacaa
     9481 cgtagagacg aaaaaatagc tgaaaagcgc aaagtattga acgaaatagg gaatcctcat
     9541 gggaaaagaa gggaaaatgt tccgataaaa gcaaaggtcc aatctcaaaa ggatagagca
     9601 ccaaagcgga ttgtgagagc aaattcgaat cccgaaatca aacgaaaatt cgctagccaa
     9661 gaaatcattt caaaaggaat aaaccaatcc tcaagtaaga aaaattcttt tcaacaagtg
     9721 aaacggcggt ctactctgtc caaacgaacc aatcgaaaag tacaaaaaag tttgaaccct
     9781 catcccaaac caaggtcagg tgagaaaaaa tgaacgtaaa gaaattaagt gccatttcgt
     9841 taactttcct aacaatctct tttatgggta tcttgatgtg tgtgggctta ttgtttggtg
     9901 aagacagtga aggaagtagt agttcaggtg ctcctcctgg ggggagtagt gtctcagaag
     9961 aggttttgaa acaccgtgca atggtggaaa aatatgccaa agaatcggat ataacagagt
    10021 atgttccgat tcttttagcg attattcaag tggaatctgg tggcacaatg gaagatgtga
    10081 tgcaaagttc tgagtcagcc ggtttaccac cgaattcatt aagtaccgag gcatccatca
    10141 aacaaggatg tctctatttt gcgtctttgg ttaagcgttc caaagaatta ggttgtgatc
    10201 aagatagtat cattcaggcc tataactttg gcggtggtta tttggactat gtggcaaaaa
    10261 acgggaagaa gcatagtttt gctttagctg aatctttttc aaaggaaaaa tcttgcggtc
    10321 aaaaaatcga ttaccctaat cccatcgcga ataaggaaaa tggtggatgg cgctataact
    10381 atggcaatat gttttattgc ttattggtga agcaatacct aactacaaca cagtttgacg
    10441 ataaaacagt ccaagggatt tttgacgagg cgtttaagta tgaaggaacg gcttatgtat
    10501 ttggtgggtc aagacccgaa acaggatttg attgtagtgg cttgactcaa tggtgttatg
    10561 ccaaagttgg tctgaaactt cctcgggtgg ctcaagatca gtatgatgcc atgacccata
    10621 ttgacctaaa agatgccaaa ccaggggatt tggttttctt tcattcgact tatgatgccg
    10681 gtacttatgt gacccatgtc ggtatttatg caggggagaa tcgcatgttt catgcaggag
    10741 atccagtagg ctggacgaat ctaacagaaa gctattggca gcagcatctt atcggtgctg
    10801 gacggtacaa ataagagaaa agaggaaaaa gaatgaagat aaaaattgaa cggaatcaaa
    10861 aggaaaagag cctaaaaaag aaaaaagaac gagtcgtatc cgtgggtaag catcgaaaaa
    10921 tggtgcttgc cctttggctt ttattatctt gtagtcttac ttttggcgtt tataaaaatt
    10981 tcaccgccat tgatcaacat acaactcatg aaaaagtggt tattaaagag aaagtagtga
    11041 atacttctgg tattgaaaac tttacgaagg atttttcgaa agaatatttt tcgtggaaaa
    11101 ataacaaaga agcaattgaa aagagaatga acaacctcga acagtacctt acagaagaag
    11161 gtttcgcttt aagtcaagat atggttcgag cagatattcc cactaattcc gaagttcagt
    11221 cagtaaaagt cttagatgtt gaaaagagct cggaggaatt tgtcgtttca tttttagtgg
    11281 agcaaaagat tacagaggga aaaaaggcac aatcgatttc ttctgcatac cgagtgacga
    11341 tctttgaaga tgaaaacagg aattatatag taacgagttt gccaactatg attgcaaaac
    11401 ctgatagggc aaaatacaag acaaaacaag tagaaaatga ttcgaaaatt gatgccaaaa
    11461 ctacagaaga aatcgctgag tttttggaaa cgttctttaa attatatcca tcagcttctg
    11521 aaaaagaatt ggagtattat gttgaaaatg atgcgatgcg accaatcaat attgacttaa
    11581 agttttcgaa gttagaggat ccagtttacc tacaaaacgg aaaaaaaatt ctagtgagta
    11641 caaagataaa ataccttgat aatgtatcaa aaaccactag ctactttcag tacaaattaa
    11701 tattacaaaa aaatggaaac tggaaaatca ttgatgttaa ataataatga ctcaatctaa
    11761 atttatgaga agttataagt agtttaactt atttcaggca gaagtcgccc atcctctata
    11821 ggtgggtgat gaatgccgtt cggtaactcg aaaaccgaca attaagacat agtgcctttt
    11881 tattttaatc catgtcataa tcagtctata taagaaatgg ttgatatacc atggaattag
    11941 atacaaataa tcattcatta tttcttcttt gttaccacct tattttagta gtgaaacatt
    12001 gtaaacatct cattgatgat gtaatgttag cttatgcaaa aaactatctt tgaaagaata
    12061 tcagaatcac atcacattac cttagttgag tgaaatcgtg ataaagacta ctttcatatt
    12121 atgctcaaag cacaacctaa aaccgaatta acaaaattca gcaatgccta agctcatgtc
    12181 tgataaaatg agactttcta agggtcaaaa atttcctttg aatacgatca ttagcttaga
    12241 taaaagtaaa aaccttagaa ctacggggat agcttggtta ataagagata tcgctgttaa
    12301 taaagacata agcttgcaag tatgctctat tcccaagaat ctcccacttc aagcactaag
    12361 gatcgttaaa ttcagctaag tggcaagtag ttcactagac gataattatc tccatatttc
    12421 aatctcagct tttccatttt tcatagcaaa ttccgttatt tttatagcat ctaaaagatt
    12481 cagcttttcc actgatcttt caccactttt cagctttttt attgtgctta aattgatacc
    12541 agtacctttt gatattgaat tggaagtaaa atcattaagg gtttttttta ttaaattcat
    12601 atccgcaatt ccagcgttca taagaatgaa gattctcctc tcatagacta ctttgaaaat
    12661 ggtactacag tggctgttta tatatttcag taggttactg tagtggtcat tttattataa
    12721 ttagaaaagg aacctaaatc aaaaatgcta aagaaaattt tcatagtatt aaacctatca
    12781 tgactaaagc cacggaattc ttgataaaag agtatacttg caagcctatg tctttactaa
    12841 cagcgatatc tcttattaac caatctatcc ccgttgttcc taaggttctt gatgttttct
    12901 aaggcaatgc ttgtatacat agcccttgat caaaatattg atactaacgt tgacgtttcg
    12961 atcatgatgt gtacggcaaa taggacaagt ccattctcga attgtgaatg acttcttacc
    13021 atctgtgtgt ccacattctg aaccaatttg actagacgga aatcatttat ctatcttgat
    13081 gatttttttg acagaagtat cgaaaatctt tacataatct gggtgttgca ttcttatgca
    13141 gatgagagcg ttagctccgt attcataacc agttgcctct aaaacgtagt ccatcggtgg
    13201 atacctagct tgcggttgcc agtggctttc gcagtcttct tgtaatcaaa tcgagcatct
    13261 aattgagtac tagtattttg aagataatac ttgagttttt cggttttcag aagttcactt
    13321 catcttccat catccatgga aatcccactc acccatacgc aggcctccaa aaattcttca
    13381 acaatggttt ttcagacatt tttctgaata cctccttgtt ttttgatacg ccagatagtc
    13441 aggaaaaagg caacaaaaca caaaacaaag ctgcctaaaa aggtaatctt cattccatat
    13501 aaaaagacat ccggccgatc tgcgatatag ttagttactc gttggcccat cttagcagac
    13561 atcgcttgat ataagaccgt cgtagaaagc gaaatcccga tgaccatccc caaatttcgg
    13621 gcaaaggaat tcatggagcc tgccagtccc aaattttcga tagtgacaga actcataacc
    13681 atcgtattat ttggggactg gaacaaggca ttgccggcac ccatgatggc agtagcgaca
    13741 atgtacagcc acaaaggaga gtccactgac aaaaacatat acatgacttg ggttaccgac
    13801 aataaaccca agcctactaa tacaaaaatc tccgggccaa cccggtcggt caggtatccg
    13861 cttaaaggcg ccccgacgac catcatcaag ggaaagacca tcatcaacag tccggcatag
    13921 ctaggactca acccgcgagc attttgcaga taaaaaggaa tcactacatt aacaaagaag
    13981 ttggaagaaa aaatcaacaa ggctgtaatc aagctcatgg taaaaatctt gttcttaaaa
    14041 ataccgaaag aaatcaatgg agaggctgct ttcttttcaa cttttaaaaa gctgacaaag
    14101 gcaatcactg aaattacgaa cagtacaagg gggactggat ggaaaaagcc actttcttgc
    14161 cccaaaaaga ttgttccaaa aaggctgata atcgtagccg caatggcagc aaagccccct
    14221 ccatcgattg tatggccgct catggtgata tcttttggta agaatttttc agcaatcaac
    14281 atcgttacga ttcccaccgg tacattgatc caaaaaatgt acgcccaaga aaattgggac
    14341 aaaatcaagc cgccaagacc tggtccagca atcgagccta atgaaacaag cgcaccgatt
    14401 gctcccaatg cccgaccacg ttcatgtatg ggaaagactt ccgtgatgat tccggcattt
    14461 gtagccatag tcatactagc accaatggct tgtaccaccc gtgcgaacaa ttaaatacct
    14521 agcgaatgat tgaacccaca caacagcgag cccaagacaa agatcagcgt accaatccga
    14581 aatactttga ttttcccaca gctatcgcca attttaccaa acagcaacaa acaagaacag
    14641 acaatcatca gataaacgga cactacccat tccgcttgat tcattggtat gcccatatca
    14701 tctgagatgg taggtagtgc aatattgaca atactgccat ccaatgtgga catgaaggta
    14761 aacatagata tagcaatcaa aatccaccag cgattttttt ggacttttgc atcttcttga
    14821 taactatgca taataggatt tcctttctaa tgatcgtgta gctaagaaca atataaccta
    14881 tgtctactgc ccaacaactt ctcgcgactc tagccatagg aagcttgagt aatttcgatt
    14941 tgttattctc atgtaaccat gtaagtttga gatgctttat ttgaacttac tctatagtaa
    15001 ctagtgataa ttcgctttac tttcttctag caatttctaa aagtcgactt cattgttctt
    15061 cagattaata gtgtgagcta tctcgtgaga cgtaagaaaa tttccattct actttttccc
    15121 aattttttca tatttatggt gttgcaccta tttgttttcc aatttgcttt tcaaatacat
    15181 tgctatgata ttcaattcca taggattata ctaaatgtca atagtatgaa taatatatta
    15241 tagatgttta tatatcactg ttaattatta tccacaataa ttaatgatta cctcgatatt
    15301 tgtcaatcaa aggttgaaac aatttatttt cagcatcttt tctaacttga gctgcactct
    15361 taatagaatc atacgatcct aaatagtacc tctttttttt aaagttatat acgcaatcca
    15421 tttctcttta gaacgataaa ctcccttaac accacttgta ttatttttcg gtaattttga
    15481 cgttagacac tctattactg tcccttcaac acatgtcctt gtttcttgcc tttttaaaca
    15541 tccacaactt tgagtatgtc caaaaaataa gttactataa cttatctcac acatactgcc
    15601 acactcacat tgacaaaccc attttgtttt ccatgaacag ttattgtcca aaggatactt
    15661 tgcagtaagt aatccgaatt ttttattttc aatgtgatgc ttttttgatt tcaaacatcc
    15721 acagcttttt acatcacctt ttagaagtcg ctttgccgat actaactttt ttctcccaca
    15781 cagacattga cattcccaaa caacagttcc ttcacttcgc agtttagttg gcttgattgc
    15841 aactaactta ccaaaagttt tatttgtcaa atttttatat ttatgcctat ttttataatt
    15901 tccacatcca caacttttgg ttctacctga tagtaagttt gatcgatata caatcgtttc
    15961 attcccacag tcacataggt aacgatattt tttatatcca ttatgagtaa tctcctcaac
    16021 aacagtaagg tgaccatatc tttccttcac tgcacctacc ctcccaagaa agaagtacca
    16081 tataatttca attaactttt aataaatcag aaaaaaatat tttcaatttt tcttagtctg
    16141 attttatgac taatttataa tacaagactg aacgatacgt acacgaaatc ctcaagatag
    16201 ataaattgtt ttcatctagt aaaacctgct caaaatatga gcataaagac ggcaataata
    16261 cactcgatat tcgataatgg acttgtttta tttgtcaaac tcatcgtaat cgagatatca
    16321 attccagtct caatatcctg atcaaaggtc taagaatcca accattttct tgttactttg
    16381 tcagattgat tacctttttt agtctccgaa taataaggtt ttcggatcaa ctaacatgct
    16441 ctgagaaaga ctactatctt tgcaaatttc caaatgaagg tgtgggccag tactattccc
    16501 agtacttcct acatagccaa ttatttgtcc ttgcaaaaca ttatctccag tttttactag
    16561 gtattgttgc tggtgagcat ataacgcggt tgatccatct tcgtgttgta tcaccacgta
    16621 atttccccaa gagtagtgaa actctgcttt aacaacctta ccagctttaa ctgcatgaat
    16681 cggctcaccc tgtgtagctg ccatatcaag tcctcggtga aattcatttc cacgatttcc
    16741 aaacaaactg gttattgaat aattatgaat aggcacttgg tatccagtct tactcatttg
    16801 tggaccttta acttctttat catagttggt taaatcatag gttttaatta attcatttag
    16861 cttcaaatag tattgtgtat ctgttgcata ccgtcctgta aggaatttag ttgcttctcg
    16921 atatgtttta ctattagctt ttaatgctcc tgcataaaaa tctttatttc cactaattcc
    16981 cttagttaat aatttggcat aatcttcaaa actttcctca tagttttcat acactctaaa
    17041 ttttgattgg gtcgtataaa gcgttccatt acccaaatct tcgtttgtta ccataatgac
    17101 aaagtttcca ttataagttc cttttatccc aaataaattg taattcggtg cctgagctaa
    17161 ctggctttga ccactggcag attctaagat cgcttgtgca atcataacag aagcatataa
    17221 atcatatttc tgaccaattt ttctcgcaga ctcaccaatt ttcataataa aattttctac
    17281 agattcattt ttgtcaaaat gaatttcttc attaccagat agtattggtt gtgattggaa
    17341 agattctgtt gattctattt gctgtggtgt cgaaaaattt tttgtttgtc cttccgtttt
    17401 tggcgcttcc ttttttgaag actctatatg gtttggtctt gtcactttcg aagaagttat
    17461 ttcacttgta ctacttgaag ttgttgaaga ttcggcactt gaaatcgtac tactttcact
    17521 tgacgaagtt gttgaagact cggcatttga agtcgtacta ctttcacttg acgaagttgt
    17581 tgaagactcg gcatttgaag tcgtactact ttcacttgat gaagttgttg aagactcagc
    17641 atttgaagtc gtactacttt cacttgataa agttgtcaaa agttcactac tctctgctgt
    17701 tacatcggaa ttactcattt cagtcgtctc ggttctttct tttgcaattt tgtatgttga
    17761 attttcgctt gccaacacat ggaaaggtgt tgctataaag agttgggaca ttaatataac
    17821 tgctgatgca agttttaaag attttttcat ttgatttacc tctctttttt ctctttaata
    17881 gtgttttcta ttaaaaatta tgataaatat tttcaatgaa ttgagtaata cagtatattt
    17941 cttgatttca tttagtaacg attatgtttc aatgtttaat cctgttactg cctttaaaat
    18001 aaaattatag ggttggctaa aactaggatg aaataaataa tctaacattt tcaatttgtc
    18061 taatgtaatt tgttcttcta tagcaagaga aaacattgat aatagtccag ataaatcttc
    18121 ttgactacaa agttgtacac ctactattct ctttgtattt ttttcaaagc taattcttaa
    18181 ttttacacga ctattttttc tcaaaaaaac aggtctaatg aaatcttcta tttctatata
    18241 atctatagac tcacttaata atcgtgctgt ttttaaattc aaacctgctg cgtaaaaatt
    18301 gtaattaaat atagaaaagc catttgtaaa ttgggaacca gaaggtgtaa aatcttgatt
    18361 gtcaatatgt tgagttgcaa tataagctgt tcttagagca ttagaaatag aaaaatcaac
    18421 actacttcta ttaatggacg taaaaaaagt tgtagcacaa tccccaatag catatatatc
    18481 ttttatattt gtttgctggt attcattagt tagatatgct ccactaacat ctctcaagag
    18541 ttcctttttg ccaattggac tattagatag aaatcctata gcttgtacga ccatatccat
    18601 agagtattgg gtaccacttg tagtgactat tttttcaatc ttttttcttc ctaaatattt
    18661 tttaggactt tctgatagac aaagatgtat tccatttttt gatagtattt cttcaacttt
    18721 atctgaaaaa ctacggtcgt aataagtcga caacactcta tctgcaacat cgaaaagata
    18781 tacttctttc cctctttttc ttatggcttc agcaatttca actccaatat atcctgctcc
    18841 aataattcct acttttttaa tagtattatc atctaaagct ttaaaaatct ctttagcatt
    18901 tggaaaattc tttatcgaaa aaatattagc taaattattc cccggtacat ctaacataat
    18961 ttgctttgaa cctgtagcta gtataagttt gtcatattct tgggaaaatc ttgtgccatc
    19021 tttttttaca caaataatct ttttattttg aatatcaatt ttgtcaactg ctgtctccaa
    19081 aaacaacttt tttatcttag aatttagttc tcttctattt tgataaaaaa gatcttctaa
    19141 attgctaact tctcttttta tgaacaacga tgtcccacat tctaagtaac taatttctga
    19201 ttttttatct atcagaataa cttcataatt tgaatcacat aagtttagaa atcgagctgc
    19261 agctagcccc gaatggtttg atccaataat tactattttt ttcacttaat cacattcttt
    19321 tcccttctat gaaaagtatc ttcattttta actaacaacc tatctcccaa aataaaaaac
    19381 aaaaagagga agaaaaagat tcttcctctt ttcagagaag atttaagaaa ttgattttct
    19441 attcattctc tttttttcga tttttatacc ctaataaccc taaagttcct aacaggatta
    19501 aaccaccact aatagtaaag atattactat caatctctcc cgtcttagga taagcttttg
    19561 aggactgctt ttgaggactg cttttgcctc tatttttgtt ttgcttgcta ccttgattgt
    19621 cagtcttatt atctttacta acggcttttt cactgtcttt ttcgtttgaa gaaacaacta
    19681 cattagtagg ttcactagta ttaccagatt catcagttgc agttactatc acttttgttc
    19741 ctgcctctaa tttaggaact ttaactgtaa aattaccatt tttatcagct gtcccatggt
    19801 attgactccc gtttggtaat gtaactgtca cctctgcatt tggttcagtt ttaccagtaa
    19861 caatttggtc accctctgta ataggatcaa cttgaggttt attcggtgct tttttatctt
    19921 ctacagaaat agtaacctct acttcttctt tagatccatc tggatatgtt actactacaa
    19981 tccctttttt gtttccagct gtactaacat ctactttctc tttccaagta taagtagttc
    20041 cttttggtag atcttctttg ttcttaattc cctcagatgc gtctggctct ttatttaagt
    20101 ctgtagtcac tttttgtcct tcaggatt
//
LOCUS       DADGHT010000052        20091 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.052, whole genome shotgun sequence.
ACCESSION   DADGHT010000052 DADGHT010000000
VERSION     DADGHT010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.052"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(125..895)
                     /locus_tag="JX887_001671"
     CDS             complement(125..895)
                     /locus_tag="JX887_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1257660.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(888..1823)
                     /locus_tag="JX887_001672"
     CDS             complement(888..1823)
                     /locus_tag="JX887_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1257661.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(2417..4066)
                     /locus_tag="JX887_001673"
     CDS             complement(2417..4066)
                     /locus_tag="JX887_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAX1257662.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(4261..5157)
                     /locus_tag="JX887_001674"
     CDS             complement(4261..5157)
                     /locus_tag="JX887_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1257663.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(5150..5830)
                     /locus_tag="JX887_001675"
     CDS             complement(5150..5830)
                     /locus_tag="JX887_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1257664.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(5831..6613)
                     /locus_tag="JX887_001676"
     CDS             complement(5831..6613)
                     /locus_tag="JX887_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1257665.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(6606..7523)
                     /locus_tag="JX887_001677"
     CDS             complement(6606..7523)
                     /locus_tag="JX887_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1257666.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(7526..7810)
                     /locus_tag="JX887_001678"
     CDS             complement(7526..7810)
                     /locus_tag="JX887_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1257667.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            8598..11825
                     /gene="fss3"
                     /locus_tag="JX887_001679"
     CDS             8598..11825
                     /gene="fss3"
                     /locus_tag="JX887_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAX1257668.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            11937..12251
                     /locus_tag="JX887_001680"
     CDS             11937..12251
                     /locus_tag="JX887_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAX1257669.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            12264..12638
                     /locus_tag="JX887_001681"
     CDS             12264..12638
                     /locus_tag="JX887_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAX1257670.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            12648..12992
                     /locus_tag="JX887_001682"
     CDS             12648..12992
                     /locus_tag="JX887_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAX1257671.1"
                     /translation="MEINVEHILDCLDQFGKGELTEEQLTNALTYDEKMFLIMHQGLL
                     EVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFLKQL
                     VETKQLPVVVND"
     gene            13061..14077
                     /locus_tag="JX887_001683"
     CDS             13061..14077
                     /locus_tag="JX887_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAX1257672.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            14671..16545
                     /gene="ltrA"
                     /locus_tag="JX887_001684"
     CDS             14671..16545
                     /gene="ltrA"
                     /locus_tag="JX887_001684"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAX1257673.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            16671..17027
                     /locus_tag="JX887_001685"
     CDS             16671..17027
                     /locus_tag="JX887_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAX1257674.1"
                     /translation="MILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRV
                     ALGRMSELGYSMMFGEVDKNFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREIS
                     NIVGLTVHTERENNSV"
     gene            17072..18214
                     /gene="dcm"
                     /locus_tag="JX887_001686"
     CDS             17072..18214
                     /gene="dcm"
                     /locus_tag="JX887_001686"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HAX1257675.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDSVAPTLTGD
                     EGIKIALPVKDGISVAGMLSGNFEQGNRIYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKGVKAYDL"
     gene            18204..18493
                     /locus_tag="JX887_001687"
                     /pseudo
     CDS             18204..18493
                     /locus_tag="JX887_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395166.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            18749..19933
                     /locus_tag="JX887_001688"
     CDS             18749..19933
                     /locus_tag="JX887_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAX1257676.1"
                     /translation="MAQRNLDYRLLKERRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     IASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            19948..20043
                     /locus_tag="JX887_001689"
     CDS             19948..20043
                     /locus_tag="JX887_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAX1257677.1"
                     /translation="MEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
BASE COUNT         6424 a         3834 c         4036 g         5797 t
ORIGIN      
        1 cactaaacgg tgttcaatca gctgaccctc ggtattcgct caaaaaacaa caaaatatga
       61 ggaactattt tcccgtttgt ttctctaata ctcaggtcaa aacgctgatt tcacaacctc
      121 ttttctaact tctcaatcct cttcctttat tgatcaaata ccaagtaacg gcgtacaaaa
      181 caacgatgaa taacacaagt acgatcatcg atgttgctac tggcacatcg atcgttccaa
      241 ggaatccgta acggaaaccg gagatcatat aaacgatcgg attgactttt gaaacagctt
      301 gccaaaaggg cggtaacata gagatggcat agaaaacgcc acctagataa gttaacggct
      361 gcaagacaaa tgtaggcacg atcgatacat catcataaga ctgagcaaaa atcccgttga
      421 gcagtcctgc taatgaaaac aagattgccg tcatcaataa tgtaatgatg accatgaacc
      481 atgaatacac atgaagtggt acaaagaaca aggaaatgat cgttacgaga gagccgacga
      541 gaatactgcg acccacacca ccaatcacaa agccccaaat aatcacatgc gtaggaacag
      601 gtgctaccaa gatttcttcg atatttttct gaaatttttg agagaagaag gacgaagaaa
      661 cattggcata cgaactagtg atagcagaca tcataatcaa accaggaacg atgaattcca
      721 tatatgaaaa accacccatg tcaccgatcc gcccaccgat catttttccg aaaataacaa
      781 aatacaagga tgtcgtgatc actggcggaa ccagtgtttg gacccatata cgcaaatagc
      841 ggttcgtttc cttgatagct aaacttttta atgcagtaaa ataaagatta aacatttttc
      901 tcctccgtat gattattttc ttctgtgatt ttcaagaaca gttcttctaa acgattcgac
      961 ttattcctca tagaaagaac tttgattcct tgtcttgtaa gctgatcgaa gattccgttc
     1021 accccttgat ttcgttcaac ttcgacagcg attgtctgct catcttcaaa tgtacaagca
     1081 tatccttcaa tcacaggttt ggtatcatat ggcgctaaat caaagataaa tgtttcaaat
     1141 tgcagttttg acagaagctc tttcatactt gtattctcga tcagttcacc cgattggatg
     1201 attccgatgt tgcgacaaag catttcagct tcttctagat aatgcgtcgt caaaatgatc
     1261 gttgtaccat tttcgttcaa ttctcgtaga aactcccaca tctcgcgtct caactcgatg
     1321 tcaactcctg ctgttggttc atccaagatc agcaaacgtg gttcatgcat caatgcccta
     1381 gcaatcatca gtcttcgctt cattcccccg gaaagcatac gtgcacggac atttctcttt
     1441 tcccaaagat tggactgctt caaatatttt tcgctgcgtt tcatcgcttc tttgcgagag
     1501 acaccgtagt agcctgcttg attcacgacg atttgctgga ccgtttcaaa agggttaaaa
     1561 ttgaactctt gtggaaccaa tccaatctgt tgctttgctc gaactagatc cttgtccaga
     1621 tcataaccga agacattcac ttttccagat gttttattga ctaaagaagt aataatcccg
     1681 atcgttgtag acttcccagc tccatttggc cctaatagcg catagaaatc tccttctttc
     1741 accgaaagat cgattccccg caatgcttcg accccacttc catagatctt tttcaaatta
     1801 tttatttcaa gcgcatttgc catttatttc ctatctcctt atagacatga ttcttaattg
     1861 tatcatggaa tacagcagat gaaaaaacaa cttggcttcc acacaaaaac acacctgcta
     1921 acaaagagga gatgtgtttt ctagttcatg atcatcttcg atagaataac tatctaaaca
     1981 actctggaac ttttaaaatc ataaaagtac cgacagcaac tactacgatg acatatagaa
     2041 gatccttata actgaggttc ttgtcttttt tattcatgtt aagctttcct ccgtcctttt
     2101 atcgaaagct tttttctttt attttaaccg aaataaataa aatggaaata gttattttca
     2161 atttctgttt tcgctgtttg ttttacggag aactttgcca tggaacgtgc gtctcgtcgc
     2221 tgatgctaag ttttttcgat aaaagctgct agaaggaaga cagcgtggtt tattttgtat
     2281 cgtcttttgc taaatcttcc aagatcatct ggacagcaga ctcgttccca ttgaattctg
     2341 ccactttttt ggcatcaatg tacttctttt gataatcgtc tttttggacc cacgcatcat
     2401 gcttcgtttg ataaagttaa tcaaacggat accactgacg ctgttcatcg aacaacaaac
     2461 tttctttttg ggcctgttca actatggatt taggataatt caaaactttc agcaaggcaa
     2521 tcgcatttcg ggtccttgaa ggtccttctt ttaatttgaa atcaaaactg attccttttc
     2581 cttctgttac ttgttcttca aagtggacat tctcacaata attctttaaa atctctgtca
     2641 attcgatatc atgtgtggcg acaaatgcta aagatggata ctccgcaagc caccgaacga
     2701 ctgaagcgga agaagcaatc cgttcgatcg tatttgttcc ttttaaaatc tcatctacga
     2761 agcagtagca gcgttctttg gaagccactt ggtccagcaa acgtttgatc gatttgattt
     2821 ctgaaacaaa ataactgtcg ccttcaaata aatcatcttc gattgccatg gaagtcaaca
     2881 catgtccagg ttgcagggta aactgttctg caatcgctgt ttggatcgtc tgtgctagaa
     2941 tacagctgat ggctatactt ttgacatacg tagattttcc tgatgcattg gaacccgtga
     3001 ctaatgtatt cttctgccag ttgactggat taactaccgc ttcttttaac aatggatgat
     3061 agatatcttt cgctgtcaca ccgccctcag taaactctgg tcggcaagtg atcggcatat
     3121 aggtgcgata attcaaaacg gctgctgcaa cttccaattc tcccagcaat tcccacagct
     3181 tgatggcttc agttgaatgc ttttctaatt tagtgagaac gaaatgatag gagataaatg
     3241 gcagcatgaa catgatgttg acatattcaa aaatcaattc tgcttcactc ccgctcttca
     3301 ttcgaaatga aaaacctaat ttagggatgt ctcttaatgg tttagtttgc tgtttcagct
     3361 ctttttgaag tggtgtcgtc atttttgcta actgattggc ggctgaaatc gttgaaacca
     3421 aataactcat gctattcagc tctgtttcta gtgtttgttt cttcactaga taatagaccg
     3481 tattgaatac taagccaccg attgctagat agattcctag tacttgccct aaaagaagca
     3541 aacctacacc caccagcgga agcaagccaa gaaaaataaa taaacctacg cgtccaatct
     3601 ttttactttt tccatccgct agatattgtt ttgcaaaatt atgatctttt tttcctaaac
     3661 gagcgaattg atattggatt ctttctctca gttgaggatt ttcctgataa aaagcaatta
     3721 gtttttctaa ctgataatct tctccaaaat caaagctacg taaacgctga tacaacgctt
     3781 ctgaacctac actagaatag gtactgttga tcccttcaaa tacttcgaac atatccaagt
     3841 cataccaagt aagatcgtcg atttcactat cccatgaacg gaattttttc tccgtgagcc
     3901 acgcatcctt caaactttct tctttatcaa atctcggttg ataaggaatt tttccccaat
     3961 tactacgaac tgtttccttt actttcaaac gtgaaaaaat gtctaaaaca actaataaaa
     4021 taacaactgc aataataatt aaaacgataa attctctttg gcccatatcc ctctccgttc
     4081 cttgatttgt tagttttagt atagcactgt tgcgctattt gaaaaggggg tacaaaaata
     4141 actgtcttcg ttacctaatt cgtatcaatc acaccaaaat aaaaacacct tccaaaaaag
     4201 aagatgtctt taaaacgaga tacaattttt tgtcattcac ttcaggtaaa ttagagccaa
     4261 ttaaaccctc cgcaacttga cggagatgga gaagatgccc ccgtctaatc tagcggtcat
     4321 ctctcctccc attccttcca ccaatttttt tgacaggtaa agcccgattc cgctagattc
     4381 cgtatttgtg cggctggtat tttcggtata aaaacgctgg aagacttttt caacagaggt
     4441 ttgcgctcct ggtttgatag gattggccac tgttaatcga atgaatgaat cctcttttga
     4501 aaatgtcacc tttgcttgtc catctgcata acgcaataaa ttctgtatga tattttgcag
     4561 cactcgcagc aacatgagcg gatctgctaa tacagttgta tttatcgagt gttcagcgaa
     4621 cgctacctcg atatttttct cagaaaattg ttcataaaaa gagaaaaata cttcttccac
     4681 ctctttagaa aaagaaagcg tatggagatc catttctttt tgcttcgtct ctattcgagc
     4741 aagatcataa aactgatccg tcatactgag taatcttgca acagattgtt tgatgatcgt
     4801 taaatacttc tcccgtttct ccgtatcctc tacctgttcc agtaattgta cataaccgtt
     4861 aatagcagtc aaaggagttc tgagatcatg agaaaggccg acgatcgata gtctgatgtt
     4921 ttcttccatt tcttgaaatg cttgtccttt ttgttcattt tcatccaccc atgtattcag
     4981 tgcatctact aggtccatta gattcttttc tcgaaattcg actgaaagac gaccaccata
     5041 ttcttgtcgt tcagaaagag tggcgatttt cttagttaat ctcttgattt ccctttgcag
     5101 gaagaaaata aaacttccca taaagataac aacgagaagc aacagccact taatcaaatc
     5161 taaaccccac tccccacacc gtatgaatat acacagcatg tgcctttgct agtttccctc
     5221 gaagattgga aatatgcata ttcactgttt tctcactatc aaaatatggt tcttgccaaa
     5281 ctgtttcata aagatttgct cgcgaaaata cttttttcgg atgttctaaa aaaagcttca
     5341 gcagatcgaa ttctcttcct gtcaaatgga cagccacacc attcacattt acatccctcg
     5401 actctttgtc cagtaagatt tccttgtaat agatgcgttg cgacagatct tttacttgga
     5461 cagaagtctg atgacgaagt tggatgccga ttcgtaacaa cagttcttcg atatcaaatg
     5521 gtttcgtcac atagtcatcc gctcctgctg ccaacaagga aactttatct ctttgatcgc
     5581 tttttgctga aagaacgatg atcggaacat tcgatgtctg tcggatttct gctaacaatg
     5641 cttcacctga aagccctgga agcatgagat ctagaaggat caaatcgaca ggatatgtgc
     5701 ttaacaataa ttttccttcc gtacctgaat aagcatcaag aagtttgtat ctctgttcaa
     5761 gaacctcctc cagtaaagaa tgaacagctt catcgtcttc gataatcaaa atagtttcca
     5821 gcaggaacac ctacttaatg tcagattttt ggaaaataaa cattcctaga gctgatgata
     5881 ccacgattgt tactagactg accagaatca ttttcggtgc ttgcgaataa gttgcttgtt
     5941 gcgcaaagtc cgtatacatg agccacgttt ccgtaaacca ctccgttaga aattccaagc
     6001 ctttgatttt tgcgaaaaca ccgggaacga aggccgttcc catgatataa agaaaagaaa
     6061 gaagcaaact gacactggta cttctagtga tgaatgtcaa agccactgga acagataatg
     6121 tcgctaatat cagcagaagc aatacaggaa atacttttag aacataattt ccatagtttt
     6181 tgattccctc aacttcacca aatccgaaag caagtgtgta agcaatcatg gctagccccg
     6241 taatcaaaac cacgccaagt gttgtgatca aaagcgtaac gagaagtttc gacacataat
     6301 aagtcattcg attccgtcct aaagataacg tattgcgaat cgtaccgttt tgaaattctt
     6361 ccccaatata aaagcacgca aatgctgcga aagccagaag aatccatgca gccatttttt
     6421 ccaccattaa aatccctgtt gcaccgttga tgactgtatc cgttgcttgg tttaattcat
     6481 tgccgtattt tgtatgcata taccattcgt tccaagaata aaaaagcgga agtacgacca
     6541 tcagtcctag tgagacccac attttacggc tcttccatac ttttattttt tcagcagtta
     6601 atagattaaa catgtggatt gcctccagtt aattgtaaga aataatcttc cagtttttgc
     6661 ccaactaggt ggataccatc cacaggaact tttgcctcta ccaatgcttg attgatggct
     6721 gctacttggt caattccttc aaaaagctgg ataacacggc tagattggac aaaataatcc
     6781 ctataaccaa gagagtcgag aaccgttact gcttgttccg tcgccgaagt gtcaattttt
     6841 ataaattgac gagattcttg tgccaattct tctttcgata attctttgat caagtgtcct
     6901 tcatgcaaaa taccgtagtg agtggcgatc tgtgacaatt catctagcaa gtggctagaa
     6961 agcaagacgg tgatgccccg ttcttttacc aaacgttgga tgatttctcg catttctgcc
     7021 atccctgctg gatccatccc attcgtcggt tcatccaaaa tcaaaaattc tggattcgtg
     7081 atcagtgcat ttgcaatagc taaacgctgg cgcataccta aagagaaatt ctttgctttc
     7141 tttttccctg tattttccaa tcgcatcatt ttcagcaggt cttcgatttc tctatccgac
     7201 acaccgccgt tcgctgcttg gatacgtagg ttatctcttg cagttaattc tggataaaga
     7261 gcaggggttt caatcgattg acccatacgt cgtcttgctg cctgcaaatc cgtcgttcca
     7321 aataattcga tcgaaccttc atcaatcgag atcaaaccca taatagttct cataaaggta
     7381 gacttacccg ctccattctc cccaatcaaa ccatagatca ttccacgttt gatttcgatc
     7441 gatactttat ctaatgcttt ggcagcaccg tattttttgg ttataccagt tgctttcaag
     7501 accgtttcat ttccaaaatc catacttatc cttctttctt attgataagt gaagtatagt
     7561 tgacgggtat aaagaaagca gccagaaatg tataaagaaa gtgtaaattt tccaattgaa
     7621 tttcaagaaa aatcagactg tctcgcagac gtggttgagt tgtctgccaa tcaaagagcg
     7681 caccaaacag tgctaatcca agtggactgg ccaccatggt aatcgttgtt atcgttgaca
     7741 tcagacgtcc ttgtatatgc gttggaactt ctcgctgaag ccagaccata taaaaagcaa
     7801 aagaaaacat taatccttaa aaacggactt atgaaaaata atacatgccg tttgggattt
     7861 acaattagct accaaataag aggttatgac aaaagacttt tcacaatccc ttcttccgaa
     7921 taaacggtgt tctcctgcca actcctcggt cacaagtcac aatatttatc aaacatgaga
     7981 agcaattttt gtaaattcct tcttatttct tgaagctgac cacttctgtc acaacctcag
     8041 aagcggataa ataatattgt ttgatgatac tttatctttt tcccgtttgt ttatagatcg
     8101 aatgatatta tagaccaaga atcctaccta ttaacatagc taaaaacaca aaaaaggcac
     8161 tttccaaatt gtggaaagtg ccagaaaagt taggattaag gtaactgcgc tcagcattgc
     8221 ttcgcccagt acgattctcg taactcgtga actcgaacga taatcgcaat taacgttttg
     8281 agaactgtga agctttacgg gctttcttaa gacctggttt tttcttcgta tcattgaata
     8341 agtttgaaaa gccttgattt ataaaggttt ttccgtaaat atattttgtt atatttgatt
     8401 aaatttgaaa tgtttgtgtt ctaaaatgtg ttctaattta aaggcagtat atttcgtatt
     8461 ttatattaaa tttttaggct cattcattct caaatccatt ctatttagtc aataaatatt
     8521 ttaaaaagac tttataaaca aagatgttca agcgagcatc ttattttttt gtgcctaatt
     8581 tgaaaggaga acatttcatg tataaaaaac aaaaaaagaa attatgtgta ttaactattt
     8641 tgagtttggc tgttcaatca attgtaggag caattgctcc tacgattgct tttgctgatg
     8701 aaattaccca tccacaaacg gtaaccgtag aactagattt agcacatcaa tatgctgttg
     8761 aaggaacttt tagtgatggt cgtccaatgt cagaagtcac tgttccgcat tatgcagttt
     8821 acaatggtgt gaagcaagat attttctgtg ttgaaccagg agtcccgatt tacaatgagt
     8881 tcactcctgg atatgagaag aacccgttac cagatatgtc cgataaagcc aaattagttt
     8941 ccgttttatg gaaaaaagta ggtacagatg cagatactca tattgtggca cagaagatga
     9001 tctggcaaga agttaatggg tatacccttc actcaataaa acgatcagat ggtagtgccg
     9061 taaatatcgc agccattgag gcaaaaatca atcaagccat tgccgattat cagaagaaac
     9121 caagcttcca taatagtacg gctaaaacag tattagggca atcgactact gtgacggata
     9181 cgaataatct gaatttgtca gagttcgatg aggttgtgga aaataccgca aacattgatt
     9241 atcgtgtgaa tggcaatcag ttgataatca gcccaaatgc caattcaaaa gaaagtggtg
     9301 tgttgacgct taagaaatct gctggtaccg gaacacctgt cgcctataaa aaggctggcc
     9361 aacagacttt aatggccggg gcgatcgata agccgaacac ttatacggtc aaaattgatg
     9421 tggaaatgga gggttctttg aagattaaaa aagttgataa agaatcgggt gatattatac
     9481 caggaacggt tttccattta gactttggaa aaactttacc cgcaaaagac gtgaccaccg
     9541 ataaagaagg cattgcgacc ttagatgaga ttcctcatgg tacaaaggta accattactg
     9601 aaaaatcggt gccggcgcct tatacgattg ataccacacc catgactgcc acaattaaag
     9661 caggtgaaac catttcagtg acttcaaaaa atacgcgaga aaaaggtcaa attattctgg
     9721 ataaaaccgg aattgaaaca gggagtgatc tttggaacga taattactct ttagcgggca
     9781 atacgtttgc cattcgcaag gatagcccaa ctggtgaaat cgtccaagaa atgaccacgg
     9841 atgaaaaagg tcatgcagaa acaccaaaag agattgccaa tgcgttggaa ttgggaacct
     9901 actatgtgac tgaaaccaag gctagtcatg gctttgtgaa tactttcaaa ccagtaaaag
     9961 tcgaattgaa ttatgtcaat caaacagtgg ctcttgttac cagtaacgta aaagggcaaa
    10021 accaagaaat tactggtgaa accactttga caaaagaaga caaagatacc ggtcatgaaa
    10081 ctcaagggaa agctgagttt aaaagagctg aatacacctt gtttactgtt aaggatggaa
    10141 aagcggtcaa atggaccgag aactttaaac cagaattgtt gaagggaacg aaagcttctg
    10201 atgaaaccgt aactttgact ttagatgaaa agaatcaagt tgccgttaaa cacttagcga
    10261 ttaatgagta ttactggcaa gaaaccaaag cgcctgaagg atataccttg gatgaaacaa
    10321 agtatcctgt atccatcaaa aaggtggatg atagcgaaaa aaatgctgtg attactcgag
    10381 atgttgcggc aaaagaacaa gtgattcgct ttggctttga tttctttaaa tttgctggat
    10441 caactactgg cactgccgaa actggcttca atgatctaac ctttaaagtg tcgccattgg
    10501 aaggaaccaa tgaaatcacc ggtgccgaag atgaagcgac cacagcttat aacgagcaat
    10561 tagggtttga tggttatggc aagtttgaaa atcttcctta tggggattat ttacttgaag
    10621 aagtagaagc cccagaaggt tttcaaaaga ttacgccatt agaaatccgt tctactttta
    10681 aagaaaataa agaggattat accaagagtg attatatctt tactattacc gaaaaagggc
    10741 aaaagcaacc gattaaaacg gtaacggtcc cttatgggaa tctaaccaat gagaatttct
    10801 cagtcagttt gaaccgtttg atgctttatg atttgcctga ggaagaagat agcttaactt
    10861 ctcttgcgac ttggaaagaa ggagataaag aattgactac tcttgattct accgagctag
    10921 tcgataaatt gagctataat ctacatgaaa tcaaagaaga ctggtatatc gtagctcaag
    10981 ccatcgatgt agatgctaca aaagctgccc aagaaaaaga taaaaaagcc aaaccggtgg
    11041 cgattgcgga aacaaccgca actttagcga ataaagagaa aacaggaact tgggagattc
    11101 tgcataaatt aactgtcgaa caagttttag acaagaccat tgtcttattc aactatgtgt
    11161 atgaaagcaa agaagcctat gaagctggtg atgagccggt agcgaaggat gctagcttga
    11221 acaatcaagc gcaaactgtt aattgtatgg tggaacgtca tgtttccatc caaaccaaag
    11281 cgcacttaga agaaggttct cagaccttta ctcatggtga cgtggtagat atgtttgatg
    11341 atgtatccat tacccatgat gtactagatg gctcaaaaga agcttttgaa acaattctgt
    11401 acgctttatt tccagatggt acaagtaaag aaatttggaa atctggcaag attgattacg
    11461 aagtgaatga caaagaattt accaaaaccg tacttgcgga aaaagtggat acaagtaaat
    11521 atccagaagg tacaagtttt accttcaaag aaattaacta tgacaaagat gggaatatca
    11581 atggaaaaca caatgaagat ttgaaagaaa aatctcaaac tttaacgccc aaaaaagttc
    11641 cgacaacacc aagtacacca gaacaatctg aaatgccaac tgttccaagt ggctctcaag
    11701 aatctagtcc tacagtgaag gcattccctc aaaccgggga gaaaacttcc aatgtgctac
    11761 tgttcattgg ctttagcttg atctttgcga cggctggcta ttatttttgg aatcgtcgga
    11821 actaaggtga taagatgaaa catgtaaata gtagaaaaca atacgcgcga ccgcctccta
    11881 aaaaagtggt cgcgctattt ttgtattcaa aactaacaat gaaaagagga aaaaatatgg
    11941 aattgaaatt tgttgtacca gatatggtcg agacgttcgg aaaactaaca tacggtggtg
    12001 aaggtgaagt tctatcggaa gggtatggtc gaaatactac aattgttggt cgaagttacc
    12061 atctgttttc aaataaacaa cgggccgatg atattgaagt ggtggtagct gcggaagccg
    12121 gcgaaaagga ttttgaccaa gatcaaccac taaaagctgt aaatccccac ttaattgcca
    12181 aaggctatga aattgagaat cgtgggttta ccgattacgt gttgtatgtt gatgatttag
    12241 tgaaagcata ggaggaaaag aagatgagat taacagaagg tattgtcgta gattcaggat
    12301 taacctttgg caagttgcgt ttttccgcat tacgtcgaga agtacgcaag caaaatgagg
    12361 acggaacggt tagtaacgag gtaaaagaac ggacctataa tttgaaatcc tccgcgcaag
    12421 gtcgaatgat ccaagtcagt attccagcaa atgtaccctt acgcgagttt gcttatgatg
    12481 cagaggtaga gctggtcaat ccaatcgtgg atacggtcgc caattatgtt tttcgggaag
    12541 gaaccaccgt taattggttt atcaaggcag atgatttagt cttgaaacga caactgaatc
    12601 aaggaaaacc tacgaaccaa aatgaaggaa agaaataggt gaagaatatg gaaattaatg
    12661 ttgaacatat tttagattgt ctcgatcaat ttggcaaagg tgagctaacg gaggaacaac
    12721 tcactaacgc attaacctat gatgaaaaaa tgtttctgat tatgcatcaa gggttactgg
    12781 aagtaggtaa cgatgccaaa gaagactttg atgtactgga ttggttaggg gaagaagagt
    12841 ctttctttat ggttgtcgag gtaaatgaaa gtttatgtcg gcaggcagaa tctgttttgg
    12901 aagaaatcga tgtggagatg ccggatgcca tcgaaagatt tttaaaacaa ttagtggaaa
    12961 cgaaacaact tcccgtagta gtaaatgact agcataactt tttgaaattg cccaatgaaa
    13021 tcctattggg ctttttcgac tggaggtgga aaccatcaaa atgtacaaag gacatcgcat
    13081 acgcgcagga gatcaacact tgatttatca ctttgttctt ggctggctaa tctttttgtt
    13141 cattggttgg atgagcgtct tttatttaca agaacttaga caatttgata tttctaaggt
    13201 atcattttcc actagtgaaa ttggctggtc tatgaaggat gtaatctgct tgctaggaag
    13261 tctcgctctt tcaggaagca tgatgttact ttatatacac ttttttcagg atcattggcg
    13321 aagtctttgg catcgacaaa agttagctcg gatgattcta gaaaaccatt ggtatgaagt
    13381 aaagcagact caaggtgaag gttttttcaa agatttgaat agtagttgga ccaaagagag
    13441 tatcagttac ttccccaaaa tttattatcg aatgaaagat ggcttacttt ctattcgcgt
    13501 tcaaatttca ctgggaaaat atcaggatca gctattgaag ttggaaaata agttagaaag
    13561 cggactgtat tgtgagttag tagaaaaaga actcaaagac tcctatgtgg aatacacctt
    13621 gttatacgat atgattgcca atcgaattgg gatagaagaa atagtggcag aaaatggggc
    13681 gttgcgattg atgaaaaatc aagtatgggc gtatgattcc ttgccgcata tgttaattgc
    13741 tggcggcaca ggtggtggga agacctattt cttactcacc attattcaag cactattgaa
    13801 gtcagatgca gaattgttta tcctcgatcc caaaaatgcg gacctcgccg atttaggtac
    13861 gataatgcct cacgtatact cccaaaaaga agaaatttct gaatgtgtgg aagattttta
    13921 cgaacgcatg atagctcgta gtaggtcaat gaaagaaatg cccaactaca aaacaggaga
    13981 gaattatgcg tatctcggac ttccgcccaa ctttttaatc tttgatgaat acgtggctta
    14041 tatgggtgcg aatcgttttc ctacaagcat cgaatagatg tgaaatggaa gcctattgag
    14101 attatcaata gtgacaacta atgttttgag agatggaatg aaagccttca agttgagctg
    14161 aaacatcccc gctaatactc ctacatgctc taatcaatga agtagattgg ttttggtatg
    14221 aagctaggtg aagtcgtctg aaatctgcct aagtgcttga gcataaggct gactataggg
    14281 cgggcggctg aaaaagataa ctatggtaag aatgtctgaa aatgactgac gaatctgcga
    14341 atgtacgggt ctaaaaggct gatcttattg aaagatagga acatacggac gtatggtgag
    14401 ataccgacaa gtaaggttcc atgatatgaa aatcgggata gctaacgaag aagctataat
    14461 ttcacaggct catagtagat acctaaggtt atacatgata gctaaaaaca ttggaacgat
    14521 gtaagcagaa aactatcaat taaatgacta cttctagata ggtgcatata agtaataacg
    14581 aaattgcttt gtttctgtga aagtaagggc acagtaccga tgaagcgtct aacaaatgtg
    14641 gagggatagc cctaagtcta tttaataaca atgaatgttg aaacagatga agttcaagga
    14701 tctggtaaga acgtgggaaa atccgttatg gaggtgccac gcttgaacac aaaaatacgt
    14761 tactgggaat attatgatct acaagaaaca ttcgatcagc tatttactca aagtagaaac
    14821 gggaaaaagt tttatcaatt atatgagtta atcatttctg aaaataatat tcttttagca
    14881 taccgtacta tcaaggcaaa caaggggtct tcgacaccag gaacggattc cttcacaatt
    14941 gataactata aggaaatgaa ccaagcagag tttatccatc ttattctcag tcatttagaa
    15001 aattacaaac caaaatccat aaagcgagta atgataccta aacccaatgg tgagaaacgc
    15061 ccattaggaa ttccatgcat gattgatcga atgatccaac agatgttcaa gcagatactg
    15121 gagccaatat gtgaagctaa gttttatgaa catagctacg gtttcagacc attgagaagt
    15181 gcaaagcatg ctctaggtcg cattatgtat ctcataaaca tcagtaaaat gcactatgca
    15241 gtagacattg atatcaaagg tttctttgat aatgtaaacc accgtttact gataaaacaa
    15301 ttatggaata taggaatttg tgacaaacaa gtcttagcta ttctttcaaa atctctgaaa
    15361 tcacccattc aaggagaagg tatcccgagc aaaggaacga tccaaggagg tatcatttct
    15421 ccactattat ctaatgttgt tctaaacgac ttagaccatt gggtctcaaa gcagtggcat
    15481 acctttgaaa caaagtatcc ctatactaaa ggttacaata aatttcgtgc tctaagagat
    15541 acaaatctaa agcaaggcta tattgtcagg tacgcagatg actttaaaat catgactaat
    15601 gattatccga cagcattaaa atggttccac gctgtcaagc tttacctaaa agacagactt
    15661 aaattagata tttccaatga gaagtctaaa atcgtcaatt tgcgtaaatg taagtcggaa
    15721 tttttaggat tcgctatttg cgtgaaacaa aaagggaaaa aatgggtttg taattcacgt
    15781 atttctaaca aaaaaaagga tcagattaaa gaagagatta aacaaagaat caaagatatt
    15841 caaaagagtc ctacagcaca aaatgctctc ctgtttaatg ctctcgtgct cggtgttcat
    15901 aattatttca ggtatgccac tcatattaat ttagatttga ataggatgaa ctacgttctt
    15961 tcattcacta cttacaaccg attatcaaat tgtagtacaa gatgttaccc caacaaagct
    16021 tccccaactt acaaaaagtt ttactcaaca acgatgaaaa cgtataaagt agctggagtc
    16081 tatttgtacc ctctttgcga cgtatctaca aaaacaattt acggatttaa tacggaggat
    16141 acaccgttta ctccgtttgg tcgtcaaaga ttggagcaca aaagcctaca gtctcttgtg
    16201 ttccaagaat taagaaaatt gatggaatcg aaaataccga atagaacggt tgagtattta
    16261 gatagtagaa tatctcgtta ctcaatgaaa tcaggcaagt gtgagattac aaaacaattt
    16321 ttgccagcaa aagccgttca ctgtcatcac tatttgccaa aaagtcttgg tggagacgac
    16381 aaattcgata acttgagaat tattcataag gatatccatc ttctgatcca tacaacaaat
    16441 aaaatgataa tcgatcacta cgtgcatgaa ctgaaactgg tgccagagca aatagcaaaa
    16501 atcaaccttt atcgaaagat gtgtaatctg caaaacattc aatagaaaat aaatagatgg
    16561 aacgccgtat gaggtgaaag tctcacgtac ggtgtggagc gggggaaaag atggagatta
    16621 tatcaaattc ttacctatcg ctatagatgt taacgacaaa agaaagtgcg gtgattttga
    16681 ataagcttaa acaaatcgtg atgttaggcc gtcaatctgg tttctttctg attctagctt
    16741 gtcaaaggcc ggatgcgaaa tatctaggag atgggattcg cgatcagttt aacttccgtg
    16801 tggctttggg tcgtatgagt gagcttgggt attccatgat gtttggagaa gtcgataaaa
    16861 atttttttat gaaacgcatc aaaggacgag gttatgtaga tacagggggc agtgtgatta
    16921 gtgagtttta tacgccactt gtaccaaaag ggtatgattt cttaagggaa attagcaaca
    16981 ttgttggatt aaccgttcat acggaaagag aaaataatag tgtgtagcct aggaatatca
    17041 ataatcctgg gcttttttat tgaggtgatt tatgacattt ttagatttat tcgccgggat
    17101 tggtggcttt cgcttaggta tggaacaagc cggtcaccag tgtatcggtt tttgtgaaat
    17161 tgatgaattt gctcggagga gttataaagc aatccatgat acaaggaagg aggtggaaat
    17221 gcatgacatc acaagtgtat cagacgaatt tgttcgatcc ctcggaccag tggacatcct
    17281 ttgcggcggc tttccgtgcc aagctttttc aattgcggga aagcggcaag gattttccga
    17341 tactcgaggt actttattct ttgaaatcgc tcggttcgcc actcttctcc aacctaagtt
    17401 tctattcctt gagaacgtcc ggggattgct caatcacgaa ggaggggcta cgttcgagac
    17461 gatcctccga acgttggatg gattggggta tgatgtggaa tggcaagtgc ttaactcaaa
    17521 ggcctacgtt ccccaaagcc gtgagcggat cttccttatc ggacattctc gagatgcatg
    17581 taccgaacaa gtatttccta tcattggatc gtcttcaaca tctgatcaaa acatcagaaa
    17641 cttggtaaat atcaatcctt ccaatcgagg aatgggtggc caagtctatg gttcagatag
    17701 cgtagcacca accttgaccg gtgatgaagg aattaaaatt gccttaccgg taaaggatgg
    17761 gatttctgta gcgggtatgt tgtcgggaaa ttttgaacaa ggcaatagga tttatgaggt
    17821 aaccggaaca gcccccactt tgtcaacgaa acaaggggga acgaagatta tgattcggaa
    17881 aaatgaaaca gaatatcaag aggtgaagcc aggggacagt gtgaacctgg cttttcctaa
    17941 ttccacaagt cgccgaggtc gtctgggaaa acaaagtgtg cataccttac taacaggaga
    18001 ccaacaagcg gtagtcacgg atcagtacca gattcgaaag ttaacaccta gggagtgctg
    18061 gcggcttcag ggctttccag attgggcttt tgatcgagct tctcaagtca attcagatag
    18121 tcagttgtat aaacaggccg gaaactcagt aacagttccg gtcatttttg atattgctag
    18181 aagattaaag ggggtaaaag catatgattt atgacgagtt gattggagaa atctactgga
    18241 tgattggcaa gattcaggca gatccgaaat tggaagaaga actgtaccgg ctcaattttg
    18301 atattcgcaa aaacggggtg aaagtccagg tgattcgtat gtagtggatg aggaaacgga
    18361 tgctcgaatg gagctcaatc aagtcatcgg tgaattggaa cgaattgcgg accttgccaa
    18421 agaacctgat atccgccaat acttgtttga gataaaagca gagttggaaa ttgagggtat
    18481 caccgcggag taatagggaa ataacccact gataggcact gaccgcgggg gatttgcgaa
    18541 gcagaaatcc tccgtggtgc tgtgcctgtt catggacggc ggcagccggc catgatgtct
    18601 caccccccgt atctaacagg ggggtacaaa aacacaaaaa acaagcaagt aaccataaaa
    18661 aatgcttgtt gtatcaagga tattaagtaa tttgtatagg tgttaactca tttggaaaag
    18721 ttaacacctt gaatttggag gtgaaaactt ggcgcaacga aatttagatt atcggttatt
    18781 aaaagaacga cgcaacgaat atggcgtttc acaaaataaa ttagctactg cttgcggact
    18841 tagccgccca tacctaaatc agatagaaaa cggtggcgta atcgcctcta caaagaccat
    18901 gagaaaaatt tttgatcaac tggaaagttt caatcccgat ttacctttaa cgttactatt
    18961 tgactatgta aggattcgct ttcccacaac ggatgtgcgg aaaattattc aagaaattct
    19021 ccatttgaaa ttcgagtata tgcttcatga agattacgcc ttttactcct atcaagaaca
    19081 atatgtcatg ggcgatattg tagtgatgtt atctcatgaa gaagataaag gtgtcctttt
    19141 ggaattaaaa ggtcgtggtt gccggcagtt tgaaactttt ttactcgccc aaaagcgtag
    19201 ctggtacgac ttttttgaag attgtctaaa agccggtggc gtgatgaaac gcttggattt
    19261 agcaatcaat gatcgagtgg ggctactgga tattcctgat ttaacgaaaa aatgtcagaa
    19321 ggaagaatgt atctccttgt ttcgtacctt caaaagttac cgttccgggg aactgttgaa
    19381 agctgatgaa aaggatggta tgggcaatac cttatatatt ggcagcctca aaagcgaggt
    19441 ttatttttgt ttgtacgaaa aagattatga acaatatatc aagttaggga ttccattgga
    19501 ccagaccgaa acgaaaaatc gttttgagat tcggttgaaa aatgaccgtg cttattatgc
    19561 gattcaagat ttgttaaaag gtcgtagcat tgaaagtacc acgttttcca ttatcaatcg
    19621 gtatttgcga tttgcggata aagtagatgg aaaacggcga accaattggc ccttgaatga
    19681 acaatggggt cgttttattg gacggaatcg gaaagagatt caattaactt ctgaaccgaa
    19741 accgtatacc attgaacgaa cattaaattg gctaggtaga caagtcgccc ctacgtggaa
    19801 aatggctaag gagttggatc gattgaatca aacaacgtat atccaggata tggtacagaa
    19861 tgcgcgactc tcggaccggc ataaaaagat tttggagcaa caaagtatgg caatcgaaaa
    19921 cttgattgta tgaaaagagg aattttgatg gaaattgtaa aagatatgtt attggtactt
    19981 ggtggcagta tgcttggtgt taccgtgatg tgcttgatga atgcaagtgc agcagcggat
    20041 tgagcaatgg aaaagaaagg aaagtgacaa aatgaatttc ggacaaaatt t
//
LOCUS       DADGHT010000053        19847 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.053, whole genome shotgun sequence.
ACCESSION   DADGHT010000053 DADGHT010000000
VERSION     DADGHT010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.053"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            168..362
                     /locus_tag="JX887_001690"
     CDS             168..362
                     /locus_tag="JX887_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257678.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="JX887_001691"
     CDS             631..930
                     /locus_tag="JX887_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257679.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="JX887_001692"
     CDS             complement(1027..1461)
                     /locus_tag="JX887_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1257680.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="JX887_001693"
     CDS             complement(1693..2403)
                     /locus_tag="JX887_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAX1257681.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="JX887_001694"
     CDS             complement(2393..3253)
                     /locus_tag="JX887_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAX1257682.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="JX887_001695"
     CDS             complement(3258..3896)
                     /locus_tag="JX887_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAX1257683.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="JX887_001696"
     CDS             complement(3911..4210)
                     /locus_tag="JX887_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1257684.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="JX887_001697"
     CDS             complement(4253..5737)
                     /locus_tag="JX887_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAX1257685.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="JX887_001698"
     CDS             complement(5757..6218)
                     /locus_tag="JX887_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1257686.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="JX887_001699"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="JX887_001699"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAX1257687.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="JX887_001700"
     CDS             7521..8291
                     /locus_tag="JX887_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAX1257688.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="JX887_001701"
     CDS             complement(8564..9391)
                     /locus_tag="JX887_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1257689.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="JX887_001702"
     CDS             9959..11194
                     /locus_tag="JX887_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAX1257690.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="JX887_001703"
     CDS             complement(12193..12453)
                     /locus_tag="JX887_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAX1257691.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="JX887_001704"
     CDS             complement(12480..13781)
                     /locus_tag="JX887_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1257692.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="JX887_001705"
     CDS             complement(14073..14531)
                     /locus_tag="JX887_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAX1257693.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..15869)
                     /locus_tag="JX887_001706"
     CDS             complement(14544..15869)
                     /locus_tag="JX887_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAX1257694.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREIMP
                     EIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVVEH
                     TDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLNDDR
                     RRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAVEK
                     LLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15886..17298)
                     /locus_tag="JX887_001707"
     CDS             complement(15886..17298)
                     /locus_tag="JX887_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1257695.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            complement(17315..18079)
                     /locus_tag="JX887_001708"
     CDS             complement(17315..18079)
                     /locus_tag="JX887_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAX1257696.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18183..19058)
                     /locus_tag="JX887_001709"
     CDS             complement(18183..19058)
                     /locus_tag="JX887_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1257697.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19313..19397)
                     /locus_tag="JX887_001710"
     tRNA            complement(19313..19397)
                     /locus_tag="JX887_001710"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19361..19363),aa:Leu,seq:caa)
     gene            complement(19415..19486)
                     /locus_tag="JX887_001711"
     tRNA            complement(19415..19486)
                     /locus_tag="JX887_001711"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19452..19454),aa:Gln,seq:ttg)
     gene            complement(19496..19568)
                     /locus_tag="JX887_001712"
     tRNA            complement(19496..19568)
                     /locus_tag="JX887_001712"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19533..19535),aa:His,seq:gtg)
     gene            complement(19630..19714)
                     /locus_tag="JX887_001713"
     tRNA            complement(19630..19714)
                     /locus_tag="JX887_001713"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19678..19680),aa:Leu,seq:caa)
     gene            complement(19735..19805)
                     /locus_tag="JX887_001714"
     tRNA            complement(19735..19805)
                     /locus_tag="JX887_001714"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19771..19773),aa:Cys,seq:gca)
BASE COUNT         6306 a         4097 c         3083 g         6361 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttatcataaa tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa
    15301 ttcttacgat cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca
    15361 caggcattaa tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac
    15421 tctggatttg tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca
    15481 atttccaata aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt
    15541 tcttgtccta ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat
    15601 cctccaacac gaatttgtga gaaaacaaaa tcgcatcctg taaaagcaag ctttggatca
    15661 tccgttgcac gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc
    15721 aagtacatat ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc
    15781 aaccgttttt cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct
    15841 ccagctatag tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa
    15901 tttattgaat tctgccataa cataagtcac ttctaagccg atgataattt gataattttt
    15961 ttcagttggt ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat
    16021 ggtgggatcc actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt
    16081 ggcttttcct ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc
    16141 taaccctaac tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg
    16201 tcctaatgtc tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaggc
    16261 aaaaaagaaa attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat
    16321 gagataatca acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca
    16381 gacaatccct gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa
    16441 catgaaacta aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct
    16501 tcccatgatt cctttgacca tctctttatt ttctttataa gctgctttat agatagctag
    16561 acatatagct ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc
    16621 ctgaggatct ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga
    16681 tgtatagctt cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg
    16741 gatcagcaaa cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag
    16801 cagttttgca aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac
    16861 agctgcgatt gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata
    16921 agaaaaaact actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa
    16981 accggaaata attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc
    17041 ttttttcaag gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt
    17101 tttgacaaaa ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc
    17161 atttccagct gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat
    17221 caatcccgct aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac
    17281 atttgattta acattcattt ttattcctcc tctattaaat atcctcatat gttactaact
    17341 caatcaaagg atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt
    17401 ggtgggtacg aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg
    17461 cgtgacacat gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat
    17521 attcttccac actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga
    17581 aacaaggctc aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa
    17641 ccggcaaatc atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat
    17701 gagtatgatg atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa
    17761 tctgagcatt ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat
    17821 aagataagga tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt
    17881 tgccacacgt caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt
    17941 tcacagcatg ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc
    18001 gctgataagc atccataatc ccataattca caccatggct atagccaaaa tcatccgaat
    18061 taaaaatcac ttttcccatt tcattctcct tcttttttct actaaaatag gcgcaaccaa
    18121 ataatcatag tccatttact atgtgtcatt tggttgcgcc tatagatagt tacgccctta
    18181 ttttaataga ttcttgctag atgaattgcc aaatagatga tttcattttc ttgaatggca
    18241 agttgaaatt gctgttcgat gatatcttta atctttagtg ctgtacaata cgctttgcta
    18301 tgtttaaatg tttcagtaaa aaaaccaata ttttctactg gcgtttcttc ctgataaatc
    18361 aagcgtttaa ccaggaattt gatatgaacc attaagcgat gataagtcag tgattcttta
    18421 tcataaacgt ttgaatagga tttttctaga tgggacaaaa tcgtggtcgt catttctact
    18481 atttttaagc tctttaaact attaggctct cctagctcag cattaatgat atgcatagtg
    18541 atgaatccta cttcatttga ccctaactcg gtttgatatc gatgattgat tcgctcgacc
    18601 acttctactg ctatatcata ttcatttgga taaaggaatc tcatttctgg caacataatt
    18661 gctgtgacat ctctatcttc tctttttcgt tgaatagcaa aataaatatg atctgtcaat
    18721 gtaatataga tatttgaatc taatggagag gagatcctag ctgttatcag ttcaatcact
    18781 tcttccgcaa aatccataaa ttcgattgga atctgcgaga ctatctcact gaatcgtttg
    18841 atcttttctt tagaatctaa tacaaataat ttgtcagcat cctcaacatc aaatggctta
    18901 ctcactttag cagaaaagcc aatccctttc cccatcgcaa ttttttctat tccatcgtca
    18961 tcgatcaata cagcattatg attcagcttt ttcatcacat acaccgttaa ttcacctcct
    19021 ctatatgata aaacaaaaca acttgcagac tccttcatac atatttttgt ctccaaacaa
    19081 tttttaaaga caaaaaacga cctaagaaag aaccctttct taggtcgtgc ctaattgaat
    19141 agtagcaccc tacataattt acaaaaatag tttaacacat aataaaagcg ttatcaatat
    19201 cttttttact cgttttatga taatacttgt atcgaattga tttggaggta attacataaa
    19261 aacaaaaaaa atatagcaac tctctataag aaagttgcta tattgataat tataccggcg
    19321 gccggggtcg aaccggcacg tcctcaacgg acactggatt ttgagtccag cgcgtctgcc
    19381 aattccgcca cgccggcaaa tttaaaaata ataactgggg tagctggatt cgaaccaacg
    19441 catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa taaagggcga
    19501 atgatgggaa tcgaacccac gaatgccgga gccacaatcc ggtgcgttaa ccacttcgcc
    19561 acattcgcca tcataaaaga tgttatttaa tttctcaata aaaaactaag atgaagacat
    19621 cttagtcaat accggcggcc ggggtcgaac cggcacgccc tcaacgggca ctggattttg
    19681 agtccagcgc gtctgccaat tccgccacgc cggcaagttg atttattagt actaaggcgg
    19741 taaccggatt tgaaccggtg atgaaggttt tgcagacctc tgccttacca cttggctata
    19801 ccgccattat actattatca atctataaaa taaagaataa attatag
//
LOCUS       DADGHT010000054        19457 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.054, whole genome shotgun sequence.
ACCESSION   DADGHT010000054 DADGHT010000000
VERSION     DADGHT010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.054"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            133..3660
                     /locus_tag="JX887_001715"
     CDS             133..3660
                     /locus_tag="JX887_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAX1257698.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="JX887_001716"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="JX887_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAX1257699.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="JX887_001717"
     CDS             7448..7789
                     /locus_tag="JX887_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1257700.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="JX887_001718"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="JX887_001718"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAX1257701.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="JX887_001719"
     CDS             9146..11566
                     /locus_tag="JX887_001719"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAX1257702.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="JX887_001720"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="JX887_001720"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAX1257703.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="JX887_001721"
     CDS             13000..13737
                     /locus_tag="JX887_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAX1257704.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="JX887_001722"
     CDS             13751..14566
                     /locus_tag="JX887_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAX1257705.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="JX887_001723"
     CDS             14579..15226
                     /locus_tag="JX887_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAX1257706.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="JX887_001724"
     CDS             15242..15898
                     /locus_tag="JX887_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAX1257707.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="JX887_001725"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="JX887_001725"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAX1257708.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="JX887_001726"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="JX887_001726"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAX1257709.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="JX887_001727"
     CDS             18240..18758
                     /locus_tag="JX887_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAX1257710.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="JX887_001728"
     CDS             18865..19365
                     /locus_tag="JX887_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAX1257711.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
BASE COUNT         6541 a         3341 c         4178 g         5397 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagc
//
LOCUS       DADGHT010000055        18498 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.055, whole genome shotgun sequence.
ACCESSION   DADGHT010000055 DADGHT010000000
VERSION     DADGHT010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.055"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            103..750
                     /locus_tag="JX887_001729"
     CDS             103..750
                     /locus_tag="JX887_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAX1257712.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            1143..3788
                     /locus_tag="JX887_001730"
     CDS             1143..3788
                     /locus_tag="JX887_001730"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAX1257713.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4098..5411
                     /locus_tag="JX887_001731"
     CDS             4098..5411
                     /locus_tag="JX887_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAX1257714.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5401..6054
                     /locus_tag="JX887_001732"
     CDS             5401..6054
                     /locus_tag="JX887_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAX1257715.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6109..6801
                     /locus_tag="JX887_001733"
     CDS             6109..6801
                     /locus_tag="JX887_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAX1257716.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6951..7151
                     /locus_tag="JX887_001734"
     CDS             6951..7151
                     /locus_tag="JX887_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAX1257717.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7405..9084)
                     /locus_tag="JX887_001735"
     CDS             complement(7405..9084)
                     /locus_tag="JX887_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAX1257718.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9086..9298)
                     /locus_tag="JX887_001736"
     CDS             complement(9086..9298)
                     /locus_tag="JX887_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAX1257719.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9691..11421
                     /gene="efrA"
                     /locus_tag="JX887_001737"
     CDS             9691..11421
                     /gene="efrA"
                     /locus_tag="JX887_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAX1257720.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11418..13178
                     /gene="efrB"
                     /locus_tag="JX887_001738"
     CDS             11418..13178
                     /gene="efrB"
                     /locus_tag="JX887_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAX1257721.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13273..13470
                     /locus_tag="JX887_001739"
     CDS             13273..13470
                     /locus_tag="JX887_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257722.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13623..14108
                     /locus_tag="JX887_001740"
     CDS             13623..14108
                     /locus_tag="JX887_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAX1257723.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14212..14805)
                     /gene="clpP"
                     /locus_tag="JX887_001741"
     CDS             complement(14212..14805)
                     /gene="clpP"
                     /locus_tag="JX887_001741"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAX1257724.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            14985..15512
                     /locus_tag="JX887_001742"
     CDS             14985..15512
                     /locus_tag="JX887_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAX1257725.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15603..16340
                     /locus_tag="JX887_001743"
     CDS             15603..16340
                     /locus_tag="JX887_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAX1257726.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16344..17261
                     /gene="miaA"
                     /locus_tag="JX887_001744"
     CDS             16344..17261
                     /gene="miaA"
                     /locus_tag="JX887_001744"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAX1257727.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17263..18492
                     /gene="hflX"
                     /locus_tag="JX887_001745"
     CDS             17263..18492
                     /gene="hflX"
                     /locus_tag="JX887_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAX1257728.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5981 a         3200 c         4022 g         5295 t
ORIGIN      
        1 ttttatttgt ctcacaccct tttccttcct acttgtaacc ttgctcccgt gttagaaaca
       61 tgttacacta aatatgtgaa attattaaca aggagcgtcg ttatgcgaga aaaaacagat
      121 acactgccaa aagcaactgc gaaaagatta cctttatatt tacgctactt gaagatgctg
      181 gatgactcag gtataagtag aatcaaatca aatgagttca gcgaaatcac ccaaattcct
      241 tctgcaacga tccgcagaga cttctcgcaa ttaggcgagc taggcagaag cggatatggc
      301 tatgatgtcc cttttcttat cgatgtattc aataatatcc ttaatactaa agaagaaaaa
      361 cgaatcgcat tagtaggata tggaaatctt ggcaaagcat tgaaacacaa caattttaga
      421 agaaatgaaa atctaaatat cgtgtgcgtc tttgataatg atccagcact gatcaatcga
      481 gtaattgatg gagaaatgat ctatccgatt gatcgtttcg cggagatagc caaagcaaaa
      541 aatgtgacag tagcaatctc tacggtacca agtaaatatt cacaatctgc tattgatgaa
      601 attgtcaaag gaaatgtaac cgctatactt aattttgcgc ctgacagagt aactgtccca
      661 gcttatgtca atgttcaata cattgatttg acaaccgagt tgcagacgct tatttacttt
      721 gatgagaatt actcagaagt tttttcttag gaaaatttga gtaggcttat tgatcttgcg
      781 agaactcgtc gtaattcttt caaaaatttt ttagtactaa atgaagtggt tttttcacga
      841 ccacttgttg actaaaaaaa aaaaccattg tagaatgaag cataacgctg aacaagagga
      901 gtaactggca cattcattct tagagagaga actatctgct gaaaggttct caatgacaac
      961 cagtgaaggt agcttgggag tttctgtctt gaatggagta gagatagacg agtcgtgatc
     1021 gttaactcac ttgagaggca ataatgattg attattgcaa tttaggtggt accgcgtaaa
     1081 tcatacgtcc tagaatacga aagtatttta ggacgttttt tagtttaaag gaggaaaaca
     1141 gcatgacgga agaaaataac ctatcaacaa aatataatcc gcaagaagtt gaagctggac
     1201 gttatcagca ttggttagaa caagatttgt ttaaaccgag cggagataaa aaagcaaaac
     1261 cttattcaat cgtaatcccg cccccaaatg ttactggaaa acttcattta gggcatgctt
     1321 gggatacgac cttgcaagat atgctgattc gtcaaaagag aatgcaagga tatgatactt
     1381 tatggctgcc tggtatggac catgcaggaa tcgcgacaca agcaaaagta gaagcgaagc
     1441 ttagagagca agggatttct cgttatgatc taggtcgtga aaagttcatc gatcaagtgt
     1501 gggaatggaa agaagagtat gcgagccaca tccgcgaaca gtgggctaaa atgggcttat
     1561 ctttagatta cagtagggaa cgttttacat tagatgatgg attatctgaa gcagtacgta
     1621 aagtttttgt taccttatac gaaaaaggtt tgatttatcg tggtgaatat atcatcaact
     1681 gggatcctca agcacgaaca gctctatctg atatcgaagt tattcataaa gatatcgaag
     1741 gcgcctttta tcatatgagc tatgaactag cagatggatc aggcgtagta gaaattgcga
     1801 caacccgtcc agaaacgatg ttgggagata cggcgattgc tgttcatcca gaagacgagc
     1861 gttatcaagc gctcatcggc aaaaaagtga ttctaccttt agtcaataaa caaatcccaa
     1921 tcattgcaga tgaatatgta gatatggaat tcgggacagg tgtagtaaaa atcactccag
     1981 cacatgatcc aaacgacttt gaggtaggta atcgtcatga tcttccacgc gtaaatgtta
     2041 tggatgatga tggtacgatg aatgaactag caggaaaata tgctggaatg gaacgttttg
     2101 ctgctcgtaa agcaatcgtg caagatctga aagaaatcgg tcgattgatt aaaatcgata
     2161 cgatgatcca cagtgtgggt cattccgagc ggacaggtgt cgttgttgaa cctcggctgt
     2221 ctactcaatg gtttgtaaaa atggcgccgt tagcgaaaaa agccattgat aaccaagaaa
     2281 cagatcaagc agtggaattc ttccctccaa gattcaatca aacgttttta cgttggatgg
     2341 aaaatgtcca tgattgggta atctcacgac aattatggtg gggacatcaa attcctgcat
     2401 ggtatcacaa agaaacaggt gaaatgtatg tagggatgga agcaccagcg gatagtgaaa
     2461 actgggtaca agatcctgat gttttagaca cttggtttag ttcagctttg tggcctttct
     2521 caacaatggg ctggccagat acggaaagcg aagattataa gcgatacttc cctactagca
     2581 ctttagtaac cggttatgac atcattttct tctgggtaag cagaatgatt ttccaaagct
     2641 tggaatttac tggcgaacgt ccatttgaga atgtcttgat tcatggattg attcgtgacg
     2701 aacaagggcg gaagatgagt aaatcattag gtaatggaat cgatccgatg gaagtaatcg
     2761 aaaagtatgg agcagatgct ctccgctggt tcttatcgaa tggttctgca ccaggacaag
     2821 atgtccgctt cagctatgaa aaaatggatg cttcttggaa ctttatcaac aaaatctgga
     2881 atgcttcacg tttcgttatc atgaatatcg aaggaatgac cgtagaagag atcgatttat
     2941 ctggagaaaa atcagtggct gaccggtgga tccttactcg tttgaatgaa acgatcgaac
     3001 gagtaactga gctatttgat cgttttgaat ttggtgaagc aggtcgacaa ctgtataact
     3061 ttatctggga tgatttttgt gactggtaca tcgaaatgag taaagaagta ctttatggag
     3121 atgatgctgt ttcaaaacaa accacccgta gcatcttagt ccatacactt gatcagatcc
     3181 tacgtttatt gcatccaatc atgccattcg ttacagaaga aatatgggaa catattcctc
     3241 atcagggaaa ttctctagta gtggcagaat atcctgttgt acgtccagag tttgatgatg
     3301 aaacagcttc taaagggatg gaagtattga aagaattgat tcgagccgtt cgaaatattc
     3361 gttcagaagt gaatacacca ttgtctaaac caattacgtt gctaattaaa acaaacgatg
     3421 ctaaaatcga tcaattttta gttgaaaata caagctatat cgaacgcttc tgtaatcccg
     3481 aagagttgac gatatcaagt gagatcactg cgccagatct agcgatgtca gctgttctga
     3541 caggtgcaga aatcttcttg ccgttagcag gattgatcaa tattgaagaa gaaatcaaac
     3601 gattagaaaa agaactggaa aagtggacaa gcgaagtaaa acgtgtccaa ggaaaacttt
     3661 ctaatgaacg ttttgtttct aacgcgccgg aagaagtagt agaggcagag cgtgcaaaag
     3721 aaaaagatta tttagagaag caaacggctg tcaaagaacg aatcgaaagt ttgcgtacta
     3781 ttcaataaga atagaaaaag agagtgtgaa atcagctagc tattactaaa agctagctga
     3841 ttgaacatcg ttacaggaaa gagtttgagc ctcactctta gcttcgattc ataaggagat
     3901 gtgacataaa ttttgtcgca tctctttttt agtctactct tattatgtag gagaaggagg
     3961 gaggtggatc atgtatcaag agtcaataaa gtagttgata aaatcgttcc tctctctgtt
     4021 tcttttctct ttgtcatact tttatttttc ttatgtgttc tatttgttat aataaaagag
     4081 aaatggggga attgttgatg acgattgaag aagcaataga atggatccat agtcgattac
     4141 catttggttc acgtcctggc cttgaccgag tcgaagcttt attagaagtg gtagggcatc
     4201 cagagagaaa agtaaaaacg atccatatcg ctggaacaaa cggaaaaggt tctactgtag
     4261 cttatttgag aagcctatta gaagaggctg ggctgacagt aggtacattt acttcacctt
     4321 atatcgaaac gttcaatgaa cggatcgcaa tcaatggcaa aagcattcca gacaatgatt
     4381 tgatccagct tgtaaaaaaa tatcagccac tgatcaaaca acttgatcaa tttgaagcag
     4441 tagctggtat tactgaattc gagacattaa cagcaatggc atttgattat tttttgatga
     4501 agaaagtgga cgtagcgatt atcgaagttg gcttaggcgg cttattggat tctaccaatg
     4561 tagctgtacc aatgctgacg ggaataacaa cgattggact tgatcatacc gaaatacttg
     4621 gagatacaat tgaagaaatc gctgcacaaa aagctggaat catcaaacaa ggcgttccag
     4681 tagtaacagg aaatattgcc ccagaagctt ttactgtcat ccaacaaaca gctaaagcaa
     4741 aaaatgcacc gctttatgta tacggggaaa attataaaat aaactatctg catcctgatg
     4801 agatgtgggg agaagtattt gaatttttta atgaaatagg aaagatccct caattaacca
     4861 ctccgctttt agggcaacat caagctgaaa atgcaggagt agccatcgaa ttgtattttg
     4921 tttactgtca attggaaaag ctgcctttcc gagaaaaaga tgttttgaag ggattgaaga
     4981 aatctcgatg gccaggaaga atggagcgtt tgagtaacga gccattagtt gttttagatg
     5041 gtgcccataa tacgcatgca atgaaccggc ttgttgagaa tttgaaaaaa gaattcaaag
     5101 gatatcaaat caacattttg ttttccgcct tacgaactaa aaatgttaga gaaatgctag
     5161 aacgattgca gcaagtacca aatgtccata tttatttgac gacctttgaa catccaaaag
     5221 ccatcgaatt aagtgaagta tcagatttag caagtgagag agtatcaatc gtttcattgt
     5281 ggcaattcgg attagcagat atattggaaa agatgacaaa tgaagacgta ttagttgtga
     5341 ccggttcact ttatttcatt tcagaagttc gccatttatt aatacaatta ggaggagatc
     5401 atgaagtata atgcagtgat ttttgacatg gatggtttgc tgttcgacac agagttagtg
     5461 tattacgaag ccacacaagt agtagcagac aagatgggtt ttccttatga taaagacctg
     5521 tatttaaaat tcttaggtgt ttcagatgaa gaagtatggg cgaattatca tatgattttc
     5581 tcggaatttg gcaaaacaag tgtacaaaga ttcatagatg attcatacca ggaaacgctt
     5641 gaacgttttt cgcaaggagc ggtacaaatg aagcccggtg tgttggaact cctctctttt
     5701 ttagaagaac atcagattcc caaagttgtc gcttccagta accaacgagc agtcattgaa
     5761 cttttattga agaagaacaa tctgtttgaa cgatttgaga cgattgtttc tgcagaaaat
     5821 gttcaacgag caaaaccaga cccagaaatt ttcttgttag ctaatcagaa gctaggtaca
     5881 gcgaagaaag aaacattgat tttagaagat tcacaaaatg gtattttagc agcttctgcg
     5941 gctgagatcc cggtagtcat ggtaccagat ctgcttccac catcccaaga attgatcaaa
     6001 aaaacagctg gggttgtttc ttctttacat gaaatccctg cattgttaaa ataaaaatcc
     6061 atctcttttc gtatcttatt ttagataaga tagaaaggag atgttttttt gggaaaacga
     6121 ttgatcaaag aagtacctac tagctcttta ccaagggaac gtatggaaat ttatggcgcg
     6181 gaagctttat cggatcagga gcttttggca atcttactgc gtaccggtca acacccttat
     6241 agtgtgatgt cgattgctgg aaatctgtta aaaacgtttg gaggactggc ctctttacga
     6301 caggctactt tgcatgagtt agaagagatt cgagggatag gacgcgtgaa agcaatcgaa
     6361 atcaaagcct tgatcgaatt aggtcgacga attcagacgg atcatgaaag agcggctcca
     6421 ccggttcgta ccagctacga attggcccag caattgattc tggaaatgaa agatcacaaa
     6481 caagaacatt tggtttgtat ttatttggac acgaagaatc aagtgatctt aaaaaaaaca
     6541 gtgttcatcg gttcgctgaa tcagtcagtc gctcatccta gagaaatttt ccattatgct
     6601 gtacgttatt gtgcagcaag gatcgtttta gcgcataatc atccttctgg taatgttatt
     6661 ccatcgcagc aggatatgaa ttttaccaaa aggatacaaa agtgtggaga aatgatgggg
     6721 atcactgtac tggaccactt gatcatcgga cgcaaacgat attttagttt gagagaagaa
     6781 ggaatgatgg aagagaagta agttgctttc ttgcaaaaaa aatgaagcaa gtgtacaatt
     6841 atattgtaat tttgtttggg aatagaagtt gaaacatctg ttgcacctct atcgtacacg
     6901 agcaatgtta caatttaaat tagtgctttt ggcacgagga ggatattatt atggaaaacg
     6961 gaacagtaaa atggttcaac gctgaaaaag gatttggatt tatctcacgt gaagatggaa
     7021 gcgacgtatt cgttcacttc tcagctatcc aaggtgacgg attcaaaaca ttagaagaag
     7081 gtcaagcagt gactttcgac gttgaagaat cagaccgcgg cccacaagct gcaaacgttg
     7141 taaaagctta attttatctg taaatcaaat tgatggtaga catcaatttt tacgagagaa
     7201 caaagcgagt aacaaaaata cctgccacaa gagacaattt ctcttgtggc aggtattttt
     7261 ttgtatgaaa aagtaaataa atttaagagg ctatgaaaga gccaccttgt atcaaggaat
     7321 aagaacaaac aaaaatggct tctcatgttt ttcatttgtt ttctcttata ttcaggacaa
     7381 ggtgctgatt tcataacctc ttatttattc ttcatctggt gtcattacca ttggcaaaat
     7441 cattggatgt ctttctgtac gttcgaataa gaaaggctga agcgcgccag tcatcgcttc
     7501 tttcaattta tattctgaac agtcaggtcc attcaaacat tctcttaaag cgtggaataa
     7561 gattcgctga gcttcattga tcatttctcc tgattctcgc atgtagacaa atccacgaga
     7621 gagaatatct ggaccagcca agatttcttt tttcttgata tccactgtcg cgacagctaa
     7681 tacaagacct tcttctgaaa gcaggtgacg gtcacgtaaa acgacattac caatatcacc
     7741 gatcccgcta ccatcgatat acacatctcc agccacaaaa tgcccagcag gacgcgcaga
     7801 atcgctagtt aacgctaaaa catcgccatt ttccatgatg aagcagtttt ctgcaggaac
     7861 acctacatct tgtgctagag aagcatgtac tttcaacatg cggaattctc cgtggacagg
     7921 aataaaatat tttggcttca tcaaacgaag cattaatttt tgttcttctt gtccaccgtg
     7981 accggaagta tggatgttat tgatttttcc gtgaatcact tctgcaccag cttcagacag
     8041 caaattgatc aaatgattga cacttgttgt attaccagga ataggtgaac ttgaaaagat
     8101 cactgtatcg tctggctgga tttggatttg acggtgagta ccattcgcga tgcggctcaa
     8161 cgcggccatc gcttctcctt gagaacctgt acataggatc atcgtttcat tggcaggcaa
     8221 gcgattgatt tcgtgtgcat ctacaaatgt gccgtctgga actttgatat atcctaaacg
     8281 ttgaccgttg acgatggcat tttccatgct tcgtccgaaa acagcgattt tacgaccagt
     8341 tgccacagcg gcatctgctg cttgctgcaa acggaagatg ttagaagcaa agctggcaaa
     8401 aatgatacgt ccttcgattt ttgaaaagat cttcaaaata gaatgcccaa tcgttttttc
     8461 tgatttagta aatgttggaa tctcagcatt tgtactatca gataaaaggc acaagactcc
     8521 ttcttccccg atacgagcca ttttatgcaa gtttgctggt tcgccaacag gagtgaaatc
     8581 gaatttgaag tctccagtcg ctacgatatt tccagaaggt gttttcacca cgatccctaa
     8641 tgcatctggg atactatggg tcgttctgaa aaagctgaca gaagtctttc taaaacggat
     8701 gatcgtatct tcattgatct catggagctc tgcatctcga agcaagccat gctcatctaa
     8761 tttgtttgtg atcaacgcta atgcgagagg accagcatag ataggaatat ttgcttgttt
     8821 cagcaagtag ggtattccgc cgatgtggtc ttcgtgcccg tgagtaatca ccaaggcttt
     8881 tactttgtgt aagttttgta tgatgtagct gtagtcggga atgacatagt caattccaag
     8941 taaatcgtct tccgggaatt tgatcccggc atcaatcaaa atgatttcat cttggaattg
     9001 taccccatac gtatttttcc cgatttcacc taatccacca atagcaaaga cgcctgtctc
     9061 gttatttttg atggaaagtt tcatattaaa actccactaa tgagaaatca gcattttctt
     9121 tttcgtactc tagatgactt ccttctagaa gttgaacgaa ttcaatattg tatggggtat
     9181 tttcttccac acgttggcga gcgtctacat cgctttttgc ctcaatgtaa agagattttg
     9241 tttcttcccg tttagggttg cgtacttttg tttcttgata ataaacttta tagatcattg
     9301 ttttgtctcc tttatctgcg taaagcagtg atttagctag ttgatttttt tagacaacac
     9361 aaaacgaggg gacaagccac ctggtttttc atatgctttg actagaatac tggattcgag
     9421 tcaaagagac aagcctcgtt tttgcttatc tgttcggata ttttttcaac cgtaccttct
     9481 gtataaaaaa tatacaacaa ttaattgtta ttctagcata aaacagcaaa taagtataga
     9541 aatcaactag attgaaagaa aaaatcaatg tttatcatcc cgctataatc ataatgactt
     9601 ttttatgaga gaagtgttct attaataggc tcgttgtgct atcattttta gtaatgaaaa
     9661 tgtaacaaaa gattaaaagg agatgagaaa gtgaaactaa tgtggcatta taccatgcgt
     9721 tataagaaat tcttgttttt caatttcata tgcgtatttg gttttatttt gattgaatta
     9781 ggacttccta cgattttagc acgtatgatc gatgtaggaa tccgcaatga tgattttgat
     9841 tatgtgaagc aacaagggat atttatgatc gttattactg taatcggtat tattttgaat
     9901 atcttgttag gttattttgg ttcgaggatt acgactaata tcgtagcaga tattcgagat
     9961 gatttgttcg aaaagatcca aagttattcg catcaggaat acgaaaatct aggcgtatct
    10021 tcattgatca ctcgtacaac aaacgatgct tatcagatca tgttgttcct gcaaaatatt
    10081 ttacgtatcg gttttatggc accaatgatg ttcattgtca gtttgtacat ggtcatgcgt
    10141 acaagtgtga cactcagttt gtatgtagta ggtgcattac ctttactatt attggcagtc
    10201 gtagcgattg ctaaggtgtc tgaaccgtta tctaaaaagc aacaaaaaaa cttagataaa
    10261 atcaacagta tcttgcggga aaatctttca ggattgcgtg tgattcgtgc attcgtcaat
    10321 gaaaagtttg aagaaaaacg ttttgctgta gtcaatgaga attatgcttc tagttcaaaa
    10381 agcttattcc gtttgatggc tgttgcacaa ccgggttttt atttcttatt taatatcgta
    10441 atggtattga tcatctggag cggggcagtg caaatcgatg caggcgagct tcgtgtagga
    10501 gatttgattg cgtttatcga gtatatattc catgccttgt tctcattcat gttatttgct
    10561 agtgtgttca tgatgtatcc aagagcagct gtttcagctg gacgtatcca agaagcccta
    10621 gatgccaaac cttcgattgt agaagatcca aatggtatat ctgatacaaa aactaaaggg
    10681 tatatcgaat ttcaaaatgt aacatttgct tatccaggcc attcgcaaga gccagtgata
    10741 cgaaatgtca gttttacagc ctctccagga gagaccgttg cttttattgg aagtaccggt
    10801 agcggaaaat ctacgttgat ccaattgatc cctcgctttt atgatgtgag tgaaggaaag
    10861 atcttgatcg atggagtaga cgtgagagat tatcggctaa gcaagttgcg agataagatt
    10921 gggtttattc cgcaaaaagc gctgctattt actggaacga ttgcagataa tttgcgatac
    10981 gggaaagaag atgctacgca agaagaaatg gaacgtgcag ctgagattgc tcaagcttca
    11041 gaattcattt ctcgaaaacc agatggattt aatgaacatt tatcagaagg tggttccaat
    11101 ttttcaggtg gacaaaaaca acgattggca atagccagag ccatcatacg ccgtccggaa
    11161 atctatattt ttgatgacag cttttctgca ttagattatc aaacggatgc gaagttacgt
    11221 gctcgtctga aaaaagaaac gacagaatct actgtattga tcgtagcaca acgtgtggga
    11281 acgatcatgc atgcagataa gatcatcgta ttaaatgaag gagaagtcgt cggtatgggg
    11341 acgcatcggg agttgttgga aaaatgcccg atttattatg atattgccgc ttctcaatta
    11401 tcaaaggagg aattagcatg aaaaaaacct tttcttcctt aaaacgttta gctcgatata
    11461 tcagaccgta tcgtgagact tttcttttag tgatcctatt tacagttctg acagtggctt
    11521 tcaacgtggc tttgccatat gttacaggac ttcctactac agaaatcagc cgtaatattg
    11581 ccaatggcga atcaatcaat ttttcttata tattcaaatg tctcatttgg atcacagttg
    11641 ttggaatagg gtattgtatt tcgcaattac tttctggtgt tttgatgaca aatgtcgttc
    11701 aaagtgccat gcatgatttg agaagagaca tagaagaaaa aatcaatcgt cttccggttt
    11761 catatttcga taaaaaccag caaggaaata ttttgtctcg tgtgacgaat gatgtagatg
    11821 cagtcagcgg tgctttacaa caagctttta ttggtatcgt aaatgcgata ttgggaatta
    11881 cgttggctgc agcaatgatg ttttatatcc agccgatgat ggcgctgatc tctatgatca
    11941 tgattccaac atcgatctgg atctcaaaac gagtgatcaa tgcttcgcag aaatattttc
    12001 aaagcatgca gaattctctt ggtgagctaa acggctacgt ccaagaaaat atgacaggtt
    12061 ttagtgtatt gaaagtatat ggacgcgaaa aagaaacatt ggaaggattc aaaaaagtta
    12121 atcacagctt gaaatacttt gggtttcgtg cagcattcat ttctggcttg atgatgcctc
    12181 tagttcaatt aactgcctat gctacttata ttggtatggc tgttctagga agcttttatg
    12241 ttattactgg ggcgatcgtt gtcggtcaac tacaagcatt catccaatat atttggcaaa
    12301 tcagtcagcc aatggggaac gtgacacaat tgtcttcagt tttgcaaagt gcatcagcgg
    12361 caacgaaacg tgtattcgag attttagatg agccagaaga aaaagaaaac aaagtagatg
    12421 cttcactgcc agaaacgatt ttaggagatg tgacattcga tcatgtcgat tttgcatatg
    12481 atccgaagaa accattaatc caagatttga attttgaagt gaaagctggt caaaccgtag
    12541 ctgtggtcgg tccgaccggt gccggcaaga cgacattgat caatctattg atgcgttttt
    12601 atgacgtaga caaaggagca ataaggattg atggaatcga caccaaatca atgagtcgca
    12661 gtgatgtgcg ttcgctattt ggtatggtct tgcaagatgc atggctttat caaggaacga
    12721 ttgcagataa tatccgcttc ggaaagcttg atgcgacaga ttatgaagta gttgatgctg
    12781 cgaaaacagc aaacgtagat cattttatcc gaacgatgcc agatggatat gatatggcca
    12841 tcaattctga gggagacaat gtgtctttag gacaaaaaca gttgctgacg attgcccgag
    12901 cagtggtctc cgatcctaaa atcttgattt tagatgaagc aacaagttca gtagacaccc
    12961 gtttagaagc gttgattcaa aaagcaatgg atcgcgtgat ggagggacgg acaagtttcg
    13021 tcatcgctca ccgtttatcg acaatccgtg atgcagatct gattctagtg atggatcaag
    13081 gtcagatcat tgaaaaagga acgcatgaga gtttattggc acaaggtgga ttttatgaaa
    13141 aactgtataa cagccaattt gctgaggaag cagaataagt catataagaa taaaacagtt
    13201 taaaacttat tttttgttct ctattcttga taatggtaaa gtaaagttat caagaaaagt
    13261 gaggacacgg agatggaaca gtttttaaat gaaaaaatta ctgaagccaa aagagaagtt
    13321 gatcgtttaa cgcacgtctg tcagacgaag ccttttgatt cagctgattt ttttgaaaat
    13381 gagtttcaaa tcgaacgctt ggcagcacaa atagaagtgt acgaattaat tttaaaaaaa
    13441 gtaatagaag aaaatataga tgtacaataa aaacaggtaa aacgtcagtt accagatact
    13501 gtaaatagac atctggcctg agcaggtttt acctgttttt tttcttatga aataaatata
    13561 tgctatgata cctttattca ataggattag tttctacaaa aaatgaaagg agaaaaataa
    13621 atatggaacg gtttatagca tcaaatgcca cagtgattgg tgatgtgaca ttgtcagaag
    13681 atgtgacgat ctggtatcaa gctgttttac gcggggacag taattggata aaaataggac
    13741 aaagaacgaa tatccaagat ggtacaatca tccatgtcga tcatgatgca cctgtagata
    13801 ttgcggagaa tgtgacggta ggacatcagt gcatgctaca tggctgtaca atcgaaaaag
    13861 gggcgctgat cgggatgggg accacgatat tgaatcatgc ggttattggt gagaatagtt
    13921 tgattggtgc tggatcatta gtaacagaag gaaaagttat tcctcctaat gtcttggctt
    13981 ttggtcgccc agctaaagtg atccgtcctt tgacaaaaga agaaatacaa aaaaacaaag
    14041 aaaacatcca gcattatgtc gagataggtc ggatgcatgc gcaaggaaaa ttcaaggagc
    14101 aaagataggc agtagcatcc ataaaataaa aaaggatggt cagtttgagt tgaccatcct
    14161 tttttatttg gtttagataa gagagcttaa aaaagcttcc tttgaaacag attaatttaa
    14221 tgaagaactg ttttccatga cttcatcgat caatccatat gcttttgctt gttcagctgt
    14281 catatagttg tcacgatctg tatctttttc aatcacttca agcggttgtc cagtgcgttc
    14341 agctaaaatt ttgtttaagc gttcgcgtgt ttgcaaaata tggcgtgccg caatttcgat
    14401 ttcagttgct tgcccttgag cgccgccaag aggttgatgg atcatgatct cagcatttgg
    14461 taaagcaaat cgtttacctt ttgtaccagc tgtcagcaag aagcttccca ttgaagcagc
    14521 catacccata acaattgttt ggacatctgc tttgacaaag ttcattgtgt cgtaaatagc
    14581 catacctgct gtaactgaac caccaggaga attgatataa agatagatat ctttttcaga
    14641 atcttgagcg tctaagaaaa gcaattgggc gatgatcgaa ttagcaagat catctgttac
    14701 ttggccgctt aacatgatga tacggtcttt caataaacgt gagtagatat cgtaagctct
    14761 ttcacctcgt gaagattgtt caatgactgt aggaattaaa ttcataatag agttcctcct
    14821 tgatttcgtt tagaaatagt gtaccataat ttagtttcta atacctaaaa tgtagtatac
    14881 atttttggtc aaaaaaggtc aaataaaaaa cttaggcaaa ttagtcgcat aaacccgctt
    14941 tatggtatga taagcagaga aacaaaacaa ggaggaacaa cagattgata gttggtatta
    15001 ctggccttat cggagtgctg acaggtgctg tagttgtcta tatcggcatg atactgcaaa
    15061 tgcgtcactt ggaaaataaa gaacagcgta gacgtgaatt ggaattgaaa gtcaaagaaa
    15121 tcgagacgct gaatcaatta aataaaaaga tcaacgagat cttgcaaaaa cggacaacgc
    15181 tgatggaaga atatgtcagc tttgatgcat ttgatgattg ttatatcacg attgacgatt
    15241 ttgcgtatct ccaatcattt tcagcgcaaa atagttttta tctgccaaat tatattttag
    15301 acgagctatt taagaatatc tcccatcgaa aagtgatttt atctccagat gaaacaatga
    15361 agattggtgg atatgcttat aaaggcggac gcgtgatttt agagaatttt acggatagtc
    15421 tgactgaaat gatcaatgaa aaaaaagctc agttgaagac tatgacgcgc cagccgattg
    15481 gtttcttctc gaaagatgat gtttggagct gatattttga agcattgccg ttgcacatga
    15541 gagcgtggta atgctttctt tttttcttaa tgatacaata gaactgaacg gagtgaagaa
    15601 agatgttaca aatctatgcc catcgcggaa gcagcggcac ccacccagaa aatacgcttc
    15661 ctgcatttgc agaagctgta cgagtaggtg cagatggtat cgaactagat gtccatctaa
    15721 gcaaagatgg ttatttgatc gttatgcacg acgaagaagt ggaccggacg actaacggta
    15781 aagggctgat tcgagaaaaa acattggaag aactcaaaaa attgaatgca gggggcaaat
    15841 tcagcaaaga atttccagca gctaaagttc ctgaattgag agaagtgtta ggactgctcc
    15901 tccaaaaaaa ttaccgaggg atgctaatga ttgaaattaa aactgatcag tatgaatatc
    15961 ccggtatcga agaaaaatta gccgaaacat taaaaagtag agattggcct tttcaacatg
    16021 catattgcag ctttcatttg gattctttgg aaaaaatcgc attactggaa ccggagatac
    16081 agctggactt attgatgagt acttctgata aaaagatcca actagcagca gaaacccctt
    16141 atatagaagg agtacatcca aaaaatactt ggttgttcga acatccagtc caggcagctg
    16201 attttccaaa agcaattcgt gcatggacga ttaacgatga agaagaaatg gccaaatgtc
    16261 aagaactcaa aatagatgga ataataactg attttccgga gaaagctctt cggtggaaac
    16321 aatcaacgaa aagtaggtaa aatatggaaa aagtattagt gatcgtcggt ccgacagcag
    16381 tcggtaaaac agcgctaagt gtggaactcg cacaactatt tggaggagag atcatcagtg
    16441 gtgattcatt gcaaatctat aaaaatctgg atatcggtac agcaaaaatc aaagaagaag
    16501 agatgaataa tgttccgcat catttgattg atgtgatcga acctactcaa cgttactcag
    16561 ccgctgattt tcagcattca ggtcgacaat tgattaccga gattgcgaac cgagggcacc
    16621 tacctatcat agctggtggt acgggtctct atatccaatc ccttctatat gattatcagt
    16681 taggagcgac agaagaagcg aatcctgaga ttagaaaaaa gtatgaaacg ttagctgaaa
    16741 caattggttc ccaagcatta tggaatcagt tgaaagaaaa agacccggca gctgctgaga
    16801 aaatccactg gaacaatcaa cgcaaagtga taagagctct ggaagtttta gagacgacag
    16861 gacatagtat cacggcacct aaagaagagc caaagcaatt gtatgattac ctcatgattg
    16921 gattagatac gaagcgtagt attctttatg aacgaatcaa tcaaagagtc gatttgatgc
    16981 tagcagaagg tttagtagca gaagcgcgta aggtgtatga gcttggagaa gtccaggcca
    17041 gtcaaggtat tggatataaa gaatttttcc cttattttga agggaaagaa acattggaag
    17101 aagcaacaga acaagtcaaa ctacattcga gaagatacgc gaaacgtcag ttgacgtggt
    17161 ttcgtaaccg tttggatgca cagtggtttg atcttataag tgagccaaat caaaaaagtc
    17221 agattgagca aacaatcaaa aaatggctgg aggcggaata aaatggaaga aaaagtgatc
    17281 atcgtagggg tagaaaccga agcaaaccag cgttactttt cagagtcaat ggaagagcta
    17341 gttcagctga cgaataccgc atcaggagaa gtcgtattca caattacaca aaagagacca
    17401 caagtggatc ggcaaacgat tatcggtaaa gggaaattac aagaattagt tcaacaagcg
    17461 gatgcgcatg aagcggattt gatcatcttt aatcatgagc taactccgag acagagccaa
    17521 ctgattaccg atgctgttgg tcttccggta attgatcgcg tgcagcttat cttagatatt
    17581 tttgcgatgc gtgctcgttc gaaagaaggg aagctgcagg ttgaacttgc tcagttagaa
    17641 tacctgctgc ctcgtttagt agggcaaggg aaaacattat ctcgtcttgg cggtgggatc
    17701 ggaacaagag ggccaggtga aacaaagtta gaaacagacc gccgacatat acggaataaa
    17761 atttttgctg ttaagaaaga attgaaagaa gtagaagctc atcgagagcg caatcgccaa
    17821 aaaagaaaaa atagcgagat ttttcagatt ggacttattg gctacacgaa tgccgggaag
    17881 tcaactatct tgaatctatt gacacaagcg gatacttatt cgaaagatca attgtttgca
    17941 acgttagatc cattgactaa gagatggcgt tttgctgaag gatttgagat tactgtaacg
    18001 gataccgtcg ggttcatcca agacctgcct acgcaactga tcgatgcttt ccattctaca
    18061 ttagaagaaa gtcaaaatat ggatcttttg ctacatgtag tcgatgctag ttctccagat
    18121 cgtattttac aggagcagac tgtcttaaaa ttgatggatg aactgaatat gaaagaaatg
    18181 ccgatactga ctgtttacaa taaggcagac cagatcgacc cagcgatgtt cacgcctacg
    18241 ctattcccaa atgtattgat ttctactcag acgaaagaag gtaagatggc gttgatcgaa
    18301 gcaatcaaac gtcagctgat ggaactaatg accccttata cactttctgt gccaagcaac
    18361 gaaggacaga aattaagcga gttgagaaga caaacaatgg ttttggacga agcgtacatg
    18421 gaagaaacaa acgaatatga agttaaaggg tttgcaaaaa ccaattcaaa atggttaaga
    18481 aaaaaccaat aaaatttt
//
LOCUS       DADGHT010000056        18136 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.056, whole genome shotgun sequence.
ACCESSION   DADGHT010000056 DADGHT010000000
VERSION     DADGHT010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.056"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(166..381)
                     /locus_tag="JX887_001746"
     CDS             complement(166..381)
                     /locus_tag="JX887_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257729.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            complement(404..1294)
                     /locus_tag="JX887_001747"
     CDS             complement(404..1294)
                     /locus_tag="JX887_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HAX1257730.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            complement(1309..2010)
                     /locus_tag="JX887_001748"
     CDS             complement(1309..2010)
                     /locus_tag="JX887_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAX1257731.1"
                     /translation="MVEWWGATIKTQSNAGRENESWGERRMSMKHKSLMPMNLQYFAE
                     GDDQKFSFDDFKSFVESNEEAQKFIQSQSQSVADKQLEAWKQNNLDKIKQDTIKEYEE
                     SKKNKSPEQIQLEKLQAEFEAEKALRVTSDNKAFVAEQIAGLELDGELKESISQFMLN
                     NLVSSDTDFTKNAVEGFTSVLNAINEKHADALKELQMKSAFGGTQQSNNQVQQNNETL
                     TNPEEQLGQILQQFN"
     gene            complement(2059..2376)
                     /locus_tag="JX887_001749"
     CDS             complement(2059..2376)
                     /locus_tag="JX887_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257732.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            complement(2378..3256)
                     /locus_tag="JX887_001750"
     CDS             complement(2378..3256)
                     /locus_tag="JX887_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAX1257733.1"
                     /translation="MMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            complement(3348..4877)
                     /locus_tag="JX887_001751"
     CDS             complement(3348..4877)
                     /locus_tag="JX887_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAX1257734.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            complement(4889..6304)
                     /locus_tag="JX887_001752"
     CDS             complement(4889..6304)
                     /locus_tag="JX887_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAX1257735.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            complement(6297..7130)
                     /locus_tag="JX887_001753"
     CDS             complement(6297..7130)
                     /locus_tag="JX887_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HAX1257736.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            complement(7289..7519)
                     /locus_tag="JX887_001754"
     CDS             complement(7289..7519)
                     /locus_tag="JX887_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257737.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            complement(8266..8733)
                     /locus_tag="JX887_001755"
     CDS             complement(8266..8733)
                     /locus_tag="JX887_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAX1257738.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            complement(8808..9248)
                     /locus_tag="JX887_001756"
     CDS             complement(8808..9248)
                     /locus_tag="JX887_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1257739.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            complement(9278..9571)
                     /locus_tag="JX887_001757"
     CDS             complement(9278..9571)
                     /locus_tag="JX887_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257740.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            complement(9602..9796)
                     /locus_tag="JX887_001758"
     CDS             complement(9602..9796)
                     /locus_tag="JX887_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257741.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            complement(9902..10354)
                     /locus_tag="JX887_001759"
     CDS             complement(9902..10354)
                     /locus_tag="JX887_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257742.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            complement(10380..10841)
                     /locus_tag="JX887_001760"
     CDS             complement(10380..10841)
                     /locus_tag="JX887_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010781228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1257743.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            complement(11042..11893)
                     /locus_tag="JX887_001761"
     CDS             complement(11042..11893)
                     /locus_tag="JX887_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1257744.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            complement(11908..12708)
                     /locus_tag="JX887_001762"
     CDS             complement(11908..12708)
                     /locus_tag="JX887_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAX1257745.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            complement(12751..13641)
                     /locus_tag="JX887_001763"
     CDS             complement(12751..13641)
                     /locus_tag="JX887_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HAX1257746.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            complement(13643..14584)
                     /locus_tag="JX887_001764"
     CDS             complement(13643..14584)
                     /locus_tag="JX887_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAX1257747.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            complement(14817..15152)
                     /locus_tag="JX887_001765"
     CDS             complement(14817..15152)
                     /locus_tag="JX887_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257748.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            complement(15478..15666)
                     /locus_tag="JX887_001766"
     CDS             complement(15478..15666)
                     /locus_tag="JX887_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257749.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            15744..15968
                     /locus_tag="JX887_001767"
     CDS             15744..15968
                     /locus_tag="JX887_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004401476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAX1257750.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            complement(16260..16472)
                     /locus_tag="JX887_001768"
     CDS             complement(16260..16472)
                     /locus_tag="JX887_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257751.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            complement(16475..16687)
                     /locus_tag="JX887_001769"
     CDS             complement(16475..16687)
                     /locus_tag="JX887_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1257752.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            16962..17372
                     /locus_tag="JX887_001770"
     CDS             16962..17372
                     /locus_tag="JX887_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1257753.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            17385..17837
                     /locus_tag="JX887_001771"
     CDS             17385..17837
                     /locus_tag="JX887_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAX1257754.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            17928..>18136
                     /locus_tag="JX887_001772"
     CDS             17928..>18136
                     /locus_tag="JX887_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257755.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLSDLNKQITMLKNDI"
BASE COUNT         5169 a         3704 c         2743 g         6520 t
ORIGIN      
        1 ttaacttttc ccatgaaata tcatttttac aagtgttgta tgattcaatt tctagcaaaa
       61 ttatttctaa taaattagtt atgcgttctt cactcaaatc tggaaaatct tcttttgtag
      121 actcaatgat ttccgttttt agcgattcat ccatcagatc acttcctaaa tttcattaac
      181 atcaattgca tcttccaaaa ttgcaattgc ttctttatca tctatagaaa tgataaattc
      241 gttatttgaa tctgctgtga taaatctacg agttttagga tgaacaaacc caacaaaatt
      301 tttagtttta cctactctat atttcacgac ttcatctttt ttagtttcat ctttttttac
      361 cactgtaatt cctcctatca aaaaagggag tactaactcc cttttattca gactttaaat
      421 ttaaaattgc cccagagttt gaagcattgt attcaagaga gtattcacct acaagaccga
      481 tacgtctaga atccgttgtt tttgcaagtt cttctgctct ccattcacgt aatggacgta
      541 gtttcacata attagtatcg attgcggcaa ttgttccttt tggcaatgat ggttctagta
      601 gagcaatacc tgtaccgtaa ttagacacga tatttccaat ttgcaatcca aaagttactc
      661 tttccccgaa ctgaacaatt tttgttgatt ttccatctaa ctcatcagtc attaactcct
      721 gcatatctgg agaaatcaag catagttttt ctcccatata acctttttca tacatcaatt
      781 taaataaagt atcgatatct tttcttgtta ctgcacccgc agtggctgtt tctgccttat
      841 ttgctgaatt gatcaagttc aaaatcccat tcattcgacg acctttagaa ccattttcat
      901 cagcttttac accagtaatc aattttcggt tcaaatcaat tttcatttcc ataccacgta
      961 gtgctacttg attagttaat tcatttccga ctccattcac attaatagca tctaatgtac
     1021 cagatacaga ggttgatttt ctaaaaattt cagtatagtt gttaaaccaa gttcgacctg
     1081 attcagcatc tggatattct ccgccctcaa gtttttcaga agaatcatcg ttgttgatat
     1141 catattcacg ccatttaatt tctgtcgagt ttgctggctc tgtttttcca gcaccaagta
     1201 aatagcttaa aaaaggtgta tttggtactt gcatagcatt aatcgctggt gaaatatcca
     1261 aatactctaa attatttaaa gatgtttttt tcataatttt tcactctcct agttaaattg
     1321 ttgaagaatt tgtcctaatt gttcttctgg atttgttaat gtttcattgt tctgctgaac
     1381 ctggttattc gattgttgag ttccaccaaa tgcagacttc atttgtagtt cttttaatgc
     1441 atctgcatgt ttctcattaa ttgcattcaa aacacttgta aaaccttcaa cagcattctt
     1501 agtgaaatct gtatccgaac taacaagatt atttagcata aattgagaaa tagactcttt
     1561 taactctcca tctagttcta atccagcaat ttgttctgca acaaatgctt tattatcact
     1621 tgtcacacgc aacgcttttt ctgcttcaaa ttcagcttgt agtttttcca gttgaatttg
     1681 ctcaggtgac ttgtttttct tagattcctc atattccttg atggtatcct gtttaatttt
     1741 atctaagtta ttttgtttcc aagcttccaa ttgtttgtcg gcaacacttt gagattgtga
     1801 ctgaataaat ttttgagctt cttcattgga ttccacaaaa gatttgaagt catcaaaaga
     1861 aaacttttga tcgtcacctt cggcaaagta ttgcaaattc attggcatta atgatttgtg
     1921 tttcatgctc attctccttt cgccccacga ttcgttttca cgccccgcat tgctttgagt
     1981 tttaatagtt gcgccccacc attcaaccaa gcccagtatt gcgctagttt aacgtcattt
     2041 cggacaaaat aaaaaagcct aattactaga ctttccttct ttgtagtcag ttctaacaac
     2101 aatacatccc atcttttcat accaatcaac tgtttctttt aaatttggta atgaatgaga
     2161 taataattga atcgttaaat taacggtatt cttatcaact ggagtattat cttgataatt
     2221 aacagtttga tcgccaataa ccacgtaggc ataattgcca ttccaatggt ctctcaagcc
     2281 attaggatgg ttctcagact caatagctgt tttgtaggct tctgcaatat cagcatttac
     2341 attaattgtt agtactgctt caaaaaaatc tttcattcta cttcctccgt ttcaaattaa
     2401 ttccaaaaga atcatgtgca aactcatcta ataaatcgcc aaataaacgg tcatattctt
     2461 catcaatatc ctttcctaat tttggtaaat taggaacatc cgtacatcta caacgactat
     2521 ggaaaggtgc tcgattttca cctatgacag catctttcag tttataggga ttcttacttg
     2581 cctttcctcc acaaatccgg caaactctct catcttttgc agtcaatacg ttgtattcct
     2641 caatacctgt ttctaaatat gatttttcaa taccatcttg tgcaaatttt gcatactccg
     2701 ttcgaacgag attttctatc gctttgttat actttgattc ttctaactta aacatgtcac
     2761 aaatttctga gtctaatctc atggtgttta atgcgtgtat aacgccttct ccactagcaa
     2821 cactttttac aatagcatta gagagtttct gttcaagcga tgaaatattt ccccaaagtc
     2881 ttcttgaaaa tgtctttcct gaccatggat agttcaaata atgtttaatt tcattttctg
     2941 gtaaataatt tggtatatca acgtttaaaa gttgaacaaa aacattagca ttagaagaat
     3001 atgttctttg aagaatttcc tctaagcgat cagaaaaata ttgattcaca tctgcatcca
     3061 tcgcatattc tgcaagaatt ttaaatacat ctgatcgtat ttgtaataag cgattgactt
     3121 ttgcatagtc aaatggtgga aaaaattcat cgataaactc tttgtatttt gcatcataca
     3181 tttttaatga cttataattt ttttccacat attcacgata ttttttctga ttacttgtac
     3241 tgtaaaactc catcatttct ggataagtga tattgtgtaa gtcagcttgt gataatagtt
     3301 ttgcttgtat ctctttcagt gcttcaggaa atacactagt taatttttta agtgtctgat
     3361 tttcttgttt gagccttgct tgatcctcca gttctcgacg tttggtccaa tacttcgttt
     3421 ctatcgtcac tattgccacc tccgccaaaa ttgtattcac tatctggata agcacttcca
     3481 ctttccaatt ccatcatttc attttcataa tcaacatctg ttacaaatgg aatttggctc
     3541 tgaatagttc gtttggatac gtatggtgca agtttaggta aagcttcagc taaataactt
     3601 aaatcagttg gcaaagatct agagaaagta aaaataattt tttcaggctc aatttctact
     3661 ttgtcatgaa acttaagaaa agcagcaatt gtttctgcgc attctttcaa tccttctcta
     3721 aaatattgct ctttagtatt tgttttcgct tctaggctaa tgatttgcca cttgcgagct
     3781 tctccagaac tgtttgattt aaacacctca tcgttaaaat cgattgcttt acaaatggtg
     3841 taaaactgtt ttttcaatag atccatatga tattcattga aatcttttgc taaatttttt
     3901 gtgacatatt cagcttttgc agtaggggct tttaagttga taatccctag ctgattcatc
     3961 atttctttag cagtgccttt gctcattgtt gtgccagtaa caagcatgta cgcaagctta
     4021 aattgttcga tttcgttttg ttgatcagac aaagcacgat caattgcatc tccaatttcc
     4081 tcagctactt caaaatcaca ataacgattc gtattatttt taaattctgc caaggtaatc
     4141 gtccccaaag ggttatcggt ctcatcaatt tttttgaacg ttccgcttgt aacaaaattc
     4201 aaatcaccat agcaagcata tgtcagaatt ttatttcttg tcataacttt catttcttga
     4261 aaaaattttt tctggtaaga gtcatacttt tctttgatat agattccggc atttccatat
     4321 ctttctgctc tccaaggttc aatattactt gctcttaact tccaaccatc atcttcttcc
     4381 acaggctcta gcaatcggaa agctactcca caagctcctt gaaaagttgc agtttcagaa
     4441 tcaagcattg cgaatctcat ggaatcaaga ttgcttgtta atttgttaaa agcttctgga
     4501 actgtcggaa gttctatatc attttttaag aatttatctt ttaatctttg aatgagtgtt
     4561 cttttttgtt ccgatacatc gtaatcccat ttgataggta taccagtaaa atgattgact
     4621 gcttggtcta cgacaattga atacatacca gcatgaagtt tattattaac ttttacaata
     4681 tcagtgttag gctttggtct attatctatt tcattctttt cgctagtata agctagatat
     4741 tttctttcgc gatcagcaaa aaatggtttc atatcttcta taaaaccatt cggatcaaac
     4801 attccatctt caatttgtgt tgcatattta acacgtagct tcttatatct ctctaaagat
     4861 aatactgtac taatcaaaag ctcacctcct aaaattgaat aaattgatag tgacttggtg
     4921 gctcataaaa cgctaaagcc agtgcgtcag caatatcggg actaccaata tttcgctttt
     4981 tcatatcatc tttactttct aaacgtatac gacttctact tgtcattttg aatttgcgag
     5041 tacttaattc tttgattaac gaactatcag aaggcaattc aataacaggc tgttctccgt
     5101 taagatttgc tgtcatattt tcttctaaca tttccttgat gtttccccat agttgagtac
     5161 ctaaattatc gtaaaaatcg tcttctgatg ttgaaccgtt attcactcca aacacctcaa
     5221 aaggataatg tttgtcttct ataagttctt ctaggcggtc ggttacacca cctccgacac
     5281 cagtgtcatc gactttaatc atcactttat caatactcgg atattgactc attagattct
     5341 tggccatgtt gatgacatat cctgttgttt ccatggtgct acgttttgaa tacttctcat
     5401 actccaatgc cctggtagca attctaggaa agagaatcgt agaatcatca ccatatcgag
     5461 ctacgtcgac accaatatga gcaacctttg ttttattgac taaagaatca ctaatttgtt
     5521 tttctgtagc caattcaact gtttcaagac tgataaatga atccaacgca cctttcggaa
     5581 attctccaaa aatacggaca cgagcaacat cactttcttt tccatatttt ttaagaatca
     5641 tttctatatt gtctttgttt gtacgtttac tatcatagct tgatacttta tgaactctgt
     5701 atttatcacg gtctgaatta tgggaatcat aaaagacacc ttcaatatta ttggggtttc
     5761 cacacatcaa cagcttatta tcaaaacctg atagcgtacc aagaatagct tccataattg
     5821 gatcagacac accagaagct tcatctacca caatcaacat atggtcctcg tgaaaacctt
     5881 gcatactttc tggtttagtc gctgttctag ccgtagcaaa ccaacgctct gaatcaccaa
     5941 ccatataaat tttggtcttt gtccacttca gtaagttttt gatcaagcta tcatttaacc
     6001 atttagctac ctctgcccaa agtacatcgt aaagttgctt cattgtcgga gctgttgcta
     6061 ttactttagc gtagggtcga cacgttaaga accaaagtat tgctcctgct tctaatgctg
     6121 tttttccaac tccttgacca gaacgaacag aaacctttga aaattcagct aaatcattta
     6181 aaacattttc ttgccattca tcaggattca aatgcaaaat atcttggcaa aaagctactg
     6241 gtttatcata gtaataatca atggcagaac caatatcagc aaaaggaata aattcattat
     6301 tcattttctt tcaccgcccg tttgtttgcg gcatttaaaa ctgcctgttt ccattcttct
     6361 atttcttcac ctgaattatt tccgccaatt tcatttgtct cagcttggat cttatcagtc
     6421 tgagctttaa ttaaatcagt tctgtattca ttcatataaa gttcattcat ttgcttgatg
     6481 gctttagcta actggttgct aatccgagtc aatgaatctt caattgaaag aatatcatca
     6541 attttgcgat gtttttttct gctaatctgc acatcttgca taacctcacg cttgatttct
     6601 agctttttac catttttttc aatcggagtt ttaatctttc ttagctgctg caatcgttcg
     6661 acttcttcat catttagtcc agcttcagct tgttggattc ttttcatcat tcgaagttgt
     6721 cttattttaa gaagtcgtat ttcttcggac aaagcaaaag aaggatcatc attcaaacta
     6781 gaatagatgt ccttctcatt atcggttaac gtgtcaaaaa atattgtttc atactcacct
     6841 gttttcaaag cgtttttatt acccactggc ggagaagctc ggctatttcc tttgttacct
     6901 ttagcatttt gattaccaat aggagcgcca ccttgattag taacgttact tttgccattg
     6961 gtaacgttac taatcaattc agcgctccat ttgtcttgcg atttccattt tctaacctga
     7021 gaatctgaaa catttaattc agatgcaatt tcctttaact gcttttctcc gttggattct
     7081 aaccaaattc ttttggcttc atcacgtctt ggatcacgtt gtcttgccat tcaatacaca
     7141 ccacctcaca ttctgtttag gttgagtttt gttttctaat tttcaatatc ttttagcatt
     7201 aaatcagctt caatcaatat ctttaaatcg gaaactttgt ctaacttgat ttgtcctgat
     7261 tggagatttt taagccattt cttgcattct aatccctcaa attcttgtta atattatttt
     7321 gaatgtttgg ttcatcatag aaaccatgac cgcaataaac gagcttgcac gcatcaatct
     7381 cacatggttc tgcttctctc cccatttcga caatagagta cttccctttg atttgtacag
     7441 aacgcacaac acgcactgaa caatcatcaa tggttcgagg atattcatta gttagcgata
     7501 cataccagta gtttctcatt atgtagcctc ctttatgtaa agaaaaagac cactcaaaga
     7561 gtgatctaat atgtaatgca caggcaggga cgtttccgat cctgtgcttg agacatttga
     7621 cgattcattt gtaccgaatc ccaaatctca atctaaccta accagttatg taatagcaac
     7681 ctacacgatg cacaaaacgc gtacgaaatt gcgcacccct atatttttaa accgccgatg
     7741 cctcggttgc caaagtcact ggcaaggaat cgaaccttgc atggttgccg aagcattgac
     7801 ctagcacaca tgcttagcgt ctaccctttc cgccacagtg acactataaa attattcttg
     7861 gctgctacta ttttttattt tgcccatttt taaatccaat catatataca ttaagacaaa
     7921 gcgcaaaaat tgaaattatt aatggaatca tttctcttca cttaccttta gttatcgtgt
     7981 gaataattaa aaaaacaata gacagcaacg gatgatagat aataagaaca atttagaagg
     8041 agttgaaatt cacatcctta ttcttaatat ttccgttgct gcctatcgaa gcttaattaa
     8101 acgatgaggg agatttcctc ccttacattt tattttgtcg atcctgtttc ctaatttttc
     8161 gacactatca taatacaacg ttgaataggt aagtgattgg tataaaaaag gtataaaatg
     8221 gaaaccaaat tggtaataaa agggtataaa aagtgtaaaa actggctact tgaaagcaac
     8281 cagttctaac gatgaagcaa attggatgat aattctgttt gattctactt taaccgattc
     8341 ttcgctagta ttattccttt gagcagttac ataaatgggc agaccattga tataacgatc
     8401 atagaatatc ttcttgcgcc tttcagtcac atcaggctta tgcggatgct gtatcgctga
     8461 atagcctcga acaaacaatt tatgcagata ctcaaattct tcctgtgctt cttctttatc
     8521 gatcagcatt ctttctgctt caaatatatg atcagctgta gaaggtggaa ccaaggaata
     8581 agatgctgtc acttttggtt ctcgatgttg ccctactcta catctagctg atagatatgc
     8641 tgaaagaaac acagcgacat tatgttttgt gcgttccata tcaacatctt tcgcgcttgg
     8701 tgtctcatat ttctttacat cgaaaagtac catcctctga ttcccccaat tatgatataa
     8761 tacttatgtc ggaaatatta ttcatagtcg gaggaatccg acttttttta ttttgtacgt
     8821 gaaatgagtt ctcctgattt atacgcctca gcaaattcaa ccaaagctac tgccttcatt
     8881 ctctcgatag ttctatcgga atatcctaat ttttctccta tttgatacat tgacatctta
     8941 ttaggaaaac aataactata ataaagtacc tggaaatgga ttctacttag ccgtgttaat
     9001 gcttcgataa ccgaatctcg agtacttatc gcttcaatga tttcttcgtt ttgactgtca
     9061 attgtgaatt tcaaattttt ggtaacagtc atcacggaaa agtctatttt cactggtccg
     9121 accaaacgtt ctaaatttct gtatcttttt agtaatcgtc tagcattttt ccttgtttgc
     9181 ttaatatcta tattctctaa aatgttcaca attgcctctt ctccttccag ttgtggaata
     9241 acgctcattg ttgtaggata gttgtaaaaa agcaaaatta agattttata acttccatgt
     9301 ccaccaatct caccactgct aaattctctt tgcttttcgc taaccactta tcacattcca
     9361 tcgtgttttc aatgcgaatg attgctgagt gattatagac gtgttctaca tatccacgaa
     9421 atggatagat gaatccttct gcttcgcagc gaaccatgtc accgactttg aattttggtt
     9481 tcttacgtgt tttaggattc tttgtcggca tatctagcat taaaccgccg atgccgtggc
     9541 cgctggagta aaatccgtct tttagtttca ttccgcttcc tcctctttag ctgtcaatta
     9601 cttactcgca agtcactaaa atggctactt catcgataaa gtttccgtct tcgtcttcca
     9661 ttccttgctg aatgctaatg tcggtaatct gcttaaaaaa ttcgttgtca tagccttgtg
     9721 cgtttatcac tacttcgacg tctccgaaaa cctctttgag actattaatt ttatttacta
     9781 cttccgatgc gtccatgact acaccccttt ccagttaaaa atctctgtcg ttaatagact
     9841 actgttcaaa gtattcatct tcactcatcc ttctgcctcc tctttagttg tcattagtgg
     9901 actaaatact acctgtttga aaaccataat gtgcagtttc aacgccgtca taatcactta
     9961 tttcccactc agccccatcg ggtatatcaa cgactttaag acttgcatat ggtccactgg
    10021 cctcacttcc tagtttttcg acaacagcaa cgaggtcctt atcacctctg tttgaatcac
    10081 ttgaaaaact ggaatcatca gcaattccgt acagtcggtc aatttcgcta taaattcctg
    10141 taactttgtc gattttcggg tcttttttga aatagtagat aaaatccatc gaacctagct
    10201 tttggcctgt gtatctcgtg tattcatcat ctgagtcata gctaaagtta ttgatgtatg
    10261 ggaatacttc aatatttttt cttttaaaaa tttccatttt tgcttcatgg ctcaacccaa
    10321 agccaccaaa acatttattt aatacaatct tcattacttt tcctcctttg tttcctccgt
    10381 tagctgaatt ttttcataaa cacaagccaa tgtgttttgc ttcgtttatt accaaacaat
    10441 ggctgttctc caatagcctc taacacatca gaaagtggta tctgttcctc gttccactta
    10501 aaaattaatg ttcctgaagg tcgtaaaact cgcatacact ctgcaaaacc ttgcctgatg
    10561 tcttctggcc aaagttcgtc taattttcca tattttttgg caagccatga gttttcgccg
    10621 acatgtctta agtgtggcgg gtcaaataca accatatcga acacatcatc ttcaaaaggc
    10681 atatcgcgaa agtctgcgac cacatctgga tcaacattga tcacatgacc tgttgataat
    10741 tcttcatact gctgacgaca atccataaat gttacgtcag aattgttctt atcaaaccag
    10801 aacaatctac taccgcaaca tgcatctaat atttttggca attactctac ctccaataac
    10861 tctggattct cgtagacgtt acctaaaaca gtgagaaatc tttctgtatc ccgataaata
    10921 attagcttac ttatcttccg aaccattcga ctctcttgtt gagataattc gtccatgtca
    10981 cgatcaccta taatttgcaa cattatctga cgacagattc ttttttcttg tttagtcaaa
    11041 ttcatgcgat cgctcctttg actggtttta tgcgcttgtc tgctgtttga gaaaatacca
    11101 tcgtaaatcc atcagagttg acaaacattc ttgatattgt tctcgtaccg taagcttttt
    11161 tcagttcttc accaagcaag ttcgttgtga taatcgttgc taggttctgt cgtgcatcca
    11221 agaacgaatt tagcgtgttt atgccaaacg ctcgactatc tgatgcatct tttcctagtt
    11281 ctgaaccgat atcatcaatg atgactaaat ccgctgtttt gatatctgca atcaacgatc
    11341 cctcaatcgt ttttctgagt tcaggattgt tgtacgaaaa tttgatttga tccagcattt
    11401 cctgtaaccc gataaataag atttttttat cgtagtttga tcgcttcaag acttcccaag
    11461 ccgctgccat cgctaggtga cttttacctg ttccttgttt tccagttaaa acaaggtgac
    11521 ttggatttcc taacaagact gaattaacaa agcgtttggt tacttcaacc gcttgtcttg
    11581 tttcttgatc gacaatttga taattctgca atgtgcaatc aaacaacgct tgattaggca
    11641 caacagaacc acctttgaaa aaattgattg ctcttgcttt caggctctcg ttgtaaattc
    11701 gttctgtttg taagtcttcc tgaactcgca atgctttata cccacattgc atacaggttg
    11761 gcttacaacg ttctgagcca tcagggttct tcgtacgcca tccatacaaa ggctgtccgc
    11821 attcaggaca ttcgccacgt tggacaagca ctttctgtat cagcttttcc atgatttccc
    11881 caacagtttc catgcctacg cctcctctca aataggcaac tcatctgtgc taaatttctc
    11941 gtattcaagc gttttagttt gttttgtttt ataatcacga tttgcttgcg ctgccattgt
    12001 gtcgtatttt tctcgcaatt ttttagcaga taaaatattc gatgcccaaa acacattgtg
    12061 ctgactccat tcaatcattc cccgtacctg gttttcggtc cgcttgtcga tctcgatcat
    12121 tttccgaatg tcatctgccc aactttgcag attcggcttt ttgatttcct gattctgaca
    12181 aatctgtttg aataactcct ccgcgagaat gtagtaaact gagtcggtgt cgtaaacacg
    12241 ctttttgcgt ggttgcgacg atgatgtttt attattcttt tcattcttat aattcttttc
    12301 attcttgttt gtgtgcactt gttgttcact tgttgtgcgt ttgatgttca tttgttgttc
    12361 actgctttgg tacaaagacc agttttttat tgatataacg ctgtatttcg tagttgattt
    12421 gatgttcaac attccgtttt tttcaaattg ttttagccat ctccatacag aaccgctgtt
    12481 cacttgatgt tcacgtttca cgccttcgtt catctcagat gtgatagcat cgcgccctgt
    12541 gacgaattct ccgctgttca cttgtatctc ttttccatta aaaagtatct tgcgattctc
    12601 atgactcgct ttcatcaaac acaagttcca taatttatac atataaggat tggtccaaac
    12661 gaatgaattc atcacttttc gatgtaattt gacatatcct gtgttcattc gtatttctcc
    12721 tctagaaaag caagggagaa agctccctca ttatttgttt aacggcggat tagatgcatc
    12781 aaataatcca gtttgtacat cttcattttc ttcagatata acctctgctt cttttctttc
    12841 aggaatatct tcttcaactt ctgtttcagc aataatgctg ccgtcttctt gaaccctttg
    12901 gactctctca tccgatgtgg tggcttcttg catttcgatg gacaagattc cccatttaga
    12961 aagaagattt ctcaaaacag tttttcgtgc cattgcattg taatcagatg cccacacacc
    13021 acttaacttt gtcttatcgc gatctttatt gttagcaatc cgatgagctt cgatttcttg
    13081 tttggtccaa tagacagttt ttttgaatcc attcagtaac tcgaaatagc caacatatcc
    13141 aatgacttca tcagacgttc taccatttgg atcaaactca aactcttctg tcagtcggtt
    13201 ccagcttttt agttctcctt cgtaaacttc gatcacattt aatgctttgt atttacctga
    13261 tcgttgggct aattggatat atcctttata gccaagcatg aattgagctt tcttttccca
    13321 ttttcctgtt tgcttgtttt tactattgaa tggaactaaa tatgcataac ctaaattctt
    13381 atctagccca agatttaatg ttgcagcagt taacgcacca ctcatgatag acatcggttc
    13441 actatctgca agataactgt cattagatac aagagtcata acattcgaca taaaagcatt
    13501 agcattgtca tgaagcacct cttcgaactt ctttctcatt gttggtgtat tcatcaaagc
    13561 tttaagtcct aattgacctg gtgcaacttg tttctgtggc tttgctgcca attgattttt
    13621 taacgattca tttgttgcca tattatttga tctccctttc ggttagcctt cttgattcag
    13681 taacgttata aatctcttca tcatttgcga catctggata tttctctgct agtttcttcg
    13741 agttcatacg tctcgtacgg acaaatttcc aactgatgat gtttttttga gtgataccga
    13801 tactggcttc acgtttacct agctcgctga taatctcgtt gtctacttga cggatagctg
    13861 attcaatttc tttcttagtc cgtttgagtt cgtttttctg ttcaactagt tcatcgaaat
    13921 gaattggtaa cgtcgtttga acgtcttcaa catctgcata cttctctttc aagaaatcag
    13981 ctgtcgcttg actaccatca ataattggct cgatacctcc aagaacgttt gtttcccaaa
    14041 actctactaa ttgttcagtg attgtatcga tcagctcttg atctcgttca atccgcttcc
    14101 agataaattt ttgaccaccg attaagacag cgatgtaaca atagtctttg tttagaacgt
    14161 tcatgtaatg ttgaacttga cagagatagc taagcggtac ctcttcgcct tcccattctt
    14221 taccgagaaa ttgattggct gttttgcatt ccagaatggc attttctccc actacttccc
    14281 gatcaatatt tgctcttaaa aatggatgta atggatgttc aaatacttgg tttcttctgc
    14341 gtactttttt gcctgtacgt tcctgaaact ctttagcaac cacttcttct aaaacattac
    14401 cccaataagc gggctcactt cctgattctt caagtactac ttgtcctgtt ttttctagcc
    14461 atagttgata aggagatttc catttattca atcctaaaat tgttccaaca tccgaacctc
    14521 cgatgccttt cttacggtct tcaagccatt cttgatggct catttctaag gtagatttac
    14581 tcatcttcat cctcctcatc aattggtgct tcatatggtg gtttagcata atcaggatca
    14641 gttaaatagt tgtcaagatt tgctaactcg ttcatgttta acctcttttc tgcttgctaa
    14701 cacgcaaagc acaagcatgg taattgcgaa taacaagcca aagattacat aacttttcgc
    14761 tacaatcact aacgtgaaaa ataaaataat gagtagatca attgtttttt cattcatcat
    14821 tgaaattccc ccttgagaat acgagtcatc acatcagcta aatcttcctt gttattaata
    14881 acaaaagtat gatttgaagg ttgattttct tcttcatttt tcgcttgttc gtaagcatcc
    14941 acagcaattc tacgcataat atgtgctgac aatgggagat tttcatctaa atgttcttct
    15001 tgcatagcaa gacaaagtaa aatttctgtt gtctcaccat aaacgagact tttaagttcc
    15061 ccttcttttt gggctgtaca aataatagaa acaccttgct tttggcattc acgtttcaat
    15121 tcttcgataa gattttcaat tttcttattc atgtgatata attctcctag ttttataaat
    15181 ttgtatgtga ctctttgctg gctggcagag tcactttttt atttgttgcc atgctttttg
    15241 cttttcgata tgttgcttgc ttaaaataat agggcggcta tttccccacc gattatcagc
    15301 aatcacttta ccgattttta gcgcttcttc tcgtgccata gttgctcctt tcttttgaat
    15361 caagcagatt gattaaaacc atcaatgctg cgaacaagct tcccccgata atactttggt
    15421 gcgctacaat cactaataac cccaaaatga atcctataaa aagtgtgtct gtcttcttca
    15481 taatctaatc tccctatttt ttatttctag cattctcaaa tcctcaagtt cagaagcaat
    15541 tagttcagct tgcctatctg atagctcatc ggcttttcta agcgctgcac ggtcatcttg
    15601 taattgtttc ctgcgttgtt taatcaaacc gagaatttga tgttcttgtt gcaaggtata
    15661 tgccatatca cttctccttt cgtttattga atttctccat ttctatttga taaaatattt
    15721 ctatagaaat ggaggtgaaa actatgggaa aaaatcaaca tgttgtacct aattccaatg
    15781 gtggttggaa tgtcaaaggt gctggaaatt ctaaagcgac tgcacatact aatacaaaat
    15841 cagaagcagt aaaaatcgct agagagattt ctaaaaatca aggatctgag ctatttattc
    15901 atggcagaga tggaaaaatt caaagccgtg atagtcacgg aaacgatcca cacccaccaa
    15961 aaggttaatc atatttagga gttaatcgaa tacgataacc gtcagcagga gttgcatcgg
    16021 tcaatgtaac ttctgctact tttttccctt cttctgtttc aataattaat cttgtgtaat
    16081 tgttctcatt caaaatccct atttttgatt cttccttcat gtcatccctc cttcgtctct
    16141 cgccgtcacc acctccaaga agaggagttg ccaaaatgaa aaaacgtgga ctttggcaaa
    16201 cttgaaagga gagcagcaac tcctcttttc agaagtggtg aatttagatt ttttagctat
    16261 taacaaacag ctctaactct aaatcgattt ttagaacgcc atgttctaaa ctgttcatat
    16321 aaatcgacat caattgttat ttctttggaa gtaactgcgt tatacccctc actaaaacgt
    16381 gattttttaa attccttcat tcttctttga taagtacttt cagaatactt atatttctct
    16441 ttaaactccg ctttgctcaa acgttgtacc atttttacgc ctcctgttct gatggctgat
    16501 cattagaatc tacttctaac ttgatatcca aaagttcttc gatttgtttt aaacgttcct
    16561 taggttttct tttttcgatg aagatatctc gtaaataagt aattgatata cccattcgtc
    16621 gagctaactc tctttgactc caacctttct ttactaaagc aattaatact tgctgtttta
    16681 aagtcatgct tcataccccc ttatcgaata ttttctaata tttttgtcta ataagtttga
    16741 caaaaactgc aaatatgcta ttatgtaagc atacaaaata cagcgcacaa aaagcgagct
    16801 tactgatgtc tggggagact attagtttat tgcttttagt ctttgtatgc cgtaaatatc
    16861 ttgcttacaa aactagtata actgcaaatt ctctatttgt aaatagataa tttgcagaaa
    16921 aatacttttt ttgtcggtat tttgaaagga atgcatatcc tatgctatta gaccgtataa
    16981 aaatcttatt aaaagaacgt tcaatgacgt tggcagaact tgaaagaaag ttaaatttcg
    17041 gaaatggaag catgtctaga tggaataaaa gtactccatc tggagataaa atacaaaaag
    17101 ttgcagatta ctttaatgta tcaactgatt atcttttagg acgtactgat aaacgccatt
    17161 attatgattt aacagaaaaa gataaacaag atattgcttt acaagctgaa aaattacttg
    17221 aaggcttgaa ttcagatgct gaaacaaatt attatggtga acctttagac gatgaagata
    17281 aggaaaaatt atacgatgcc attcaacttg cacttgcctt aaccaaagtt aaagcaaaga
    17341 aaaaattcac tcctaaaaaa tatcgtcaat aggtgggctt tggtatgcat ttaaacaaat
    17401 actggatatt agaagaaata gaaaaattat ttgtagagtt tggatctgat gcgattaatc
    17461 catataaaat aatcaaatat tctgatatag atttaattga aactgattta gggaataaaa
    17521 cattaggaca aacgatacac aataaaagat gttatgtgat attaattaat caaaacctat
    17581 caccttctat gaaaagattt gtattatggc atgaaatagc ccacgttaga ctccataaag
    17641 gtatttgcac agcagctttt agagcaaaca accttagttg tatgatttat ggtatagaag
    17701 ctgaagctaa tatgtttgca attgaaatgt taactagaac aatagatgaa caagatttat
    17761 ctgatatgag tcagttccaa attattgaat atttagggct tcctcataat cttgaacatt
    17821 tagtattaca acattaaaaa taaaaaagcc catgctttca catggactct ttcctcattt
    17881 ctgagtaaac tctacaataa ttatatcaaa gaaatgagga gttttgaatg ttattattga
    17941 ttggacttat tttattaatt ataggaatca ctaaactgtc gaaagctaac acaataaaaa
    18001 aagaagctta tgaattagaa caaaaaaatg atgaaaaact aaataaatta catgatagag
    18061 aaagatttat attaagtaag gaagaaacac tatcagattt aaataaacaa attactatgt
    18121 taaaaaatga tattat
//
LOCUS       DADGHT010000057        17993 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.057, whole genome shotgun sequence.
ACCESSION   DADGHT010000057 DADGHT010000000
VERSION     DADGHT010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.057"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1368)
                     /locus_tag="JX887_001773"
     CDS             complement(<1..1368)
                     /locus_tag="JX887_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1257756.1"
                     /translation="MQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINMVP
                     AFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLRMQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDF"
     gene            complement(1328..3082)
                     /locus_tag="JX887_001774"
     CDS             complement(1328..3082)
                     /locus_tag="JX887_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1257757.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLK
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(3192..3761)
                     /locus_tag="JX887_001775"
     CDS             complement(3192..3761)
                     /locus_tag="JX887_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAX1257758.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(3779..5203)
                     /locus_tag="JX887_001776"
     CDS             complement(3779..5203)
                     /locus_tag="JX887_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAX1257759.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGG
                     IKKDIKLRVEDSTLIEQIFNDITK"
     gene            complement(5205..5873)
                     /locus_tag="JX887_001777"
     CDS             complement(5205..5873)
                     /locus_tag="JX887_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAX1257760.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(6004..6588)
                     /locus_tag="JX887_001778"
     CDS             complement(6004..6588)
                     /locus_tag="JX887_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1257761.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(6923..7153)
                     /locus_tag="JX887_001779"
     CDS             complement(6923..7153)
                     /locus_tag="JX887_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAX1257762.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKRF"
     gene            complement(7168..8118)
                     /locus_tag="JX887_001780"
     CDS             complement(7168..8118)
                     /locus_tag="JX887_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAX1257763.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(8115..8957)
                     /locus_tag="JX887_001781"
     CDS             complement(8115..8957)
                     /locus_tag="JX887_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAX1257764.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            complement(9090..9815)
                     /locus_tag="JX887_001782"
     CDS             complement(9090..9815)
                     /locus_tag="JX887_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAX1257765.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGGTA"
     gene            complement(10276..10590)
                     /locus_tag="JX887_001783"
     CDS             complement(10276..10590)
                     /locus_tag="JX887_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAX1257766.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
     gene            complement(10606..12201)
                     /locus_tag="JX887_001784"
     CDS             complement(10606..12201)
                     /locus_tag="JX887_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HAX1257767.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            complement(12224..13114)
                     /gene="iolE"
                     /locus_tag="JX887_001785"
     CDS             complement(12224..13114)
                     /gene="iolE"
                     /locus_tag="JX887_001785"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015076872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HAX1257768.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            complement(13131..14156)
                     /gene="iolG"
                     /locus_tag="JX887_001786"
     CDS             complement(13131..14156)
                     /gene="iolG"
                     /locus_tag="JX887_001786"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HAX1257769.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            complement(14180..15187)
                     /locus_tag="JX887_001787"
     CDS             complement(14180..15187)
                     /locus_tag="JX887_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1257770.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            complement(15300..16460)
                     /locus_tag="JX887_001788"
     CDS             complement(15300..16460)
                     /locus_tag="JX887_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HAX1257771.1"
                     /translation="MNIQLKMPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTG
                     HLQKIKELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTA
                     KVVAVLAANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKM
                     MMKDLVFMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEA
                     MKKILNTLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPH
                     GISNAMLLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLS
                     IPTIRDYGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            complement(16536..17990)
                     /locus_tag="JX887_001789"
     CDS             complement(16536..17990)
                     /locus_tag="JX887_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010825391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HAX1257772.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
BASE COUNT         5559 a         3759 c         2812 g         5863 t
ORIGIN      
        1 aaagtcttcg cagttagcta aacgagctgc ttttttcact tcctcatctg acgcttgact
       61 atttccaata cgtatatttt ccaaaatact tgtattaaac aaagttacct cttgaaaaac
      121 aatagcgatt ttgctaaaca aagaagctgg agatacacgt ttaatatcat acccatcaat
      181 taaaatacag ccttcatcat aatcatacag tctagacact aatttcaaga tactagtttt
      241 cccggaacca ctagcaccta ctaacgcagt cacttctcct tgtttagccg taaaagagat
      301 atgatctaaa attggggtat tgttatcata tgagaaagag acatctcgca actcaatgtc
      361 aaaagatttc agaggactat ctgatccctc ttggatactg gtttccttca tagctctaat
      421 tcgctgtatt ttaggagcta aataaaatat ttcaagcact gcttctttca tagaatcgaa
      481 ggaatccttt atttttattg cggctagtaa gtaaccaacg acgtagagta tagtcacttc
      541 acccgttaac agtaagtgaa cacctactag aatgactact gctaaactaa catatgagaa
      601 aatagaggat aaggccatga ctgaaaaagt acttaattct acctttaaat gaatcctttc
      661 actctcttcc atttttttga aaagtctgtc ttgaactttt ttagatagat taaagctatt
      721 aatctcttgc tgcaattcta tagtttcttg aaattcttcc gagttttctc tcaaagtatc
      781 gtaatattta gtattggctt tcgtttggga tttctttgat aacaagatta agacaaaact
      841 aaataacgtt ggcaaaataa cagctaatcc cattttgaca ttaccaacca aaagcatcac
      901 tgaaataaaa gggaaaaaca gagccatacc gccggcttta ggtattgcat gactcatcgc
      961 atgctcaata ccttcaacgt cagacatgat agtttgagat aaatctgata aattatgttt
     1021 tgaaaaatag gataatggta aatttgacaa atcgtctgca atttgcattc ttaaatgcgc
     1081 actttcttta taagtactat tatataagtt ttcatactcc ctatctaaca accaatacat
     1141 gaaaagcaaa gtaacgaacg atactgtaaa ataaagccaa ggcggcttta cattttctaa
     1201 aactaattcg tctatcagca tcattataat gaatgctggt accatattaa tgcagtatac
     1261 aaaaaagcta gaaatagatg ctttaaccaa atcttctgcg ccctgattag ttaaagcgaa
     1321 tttgttttta taaaaacttt tcattgtcaa gcctccaatc atttgcattc tcataattag
     1381 tgaccaattg tttatacact tgatgtttag ccattaattc attatgattt ccacgttcta
     1441 ctattttccc ttctgacaag acaagaattt catctacaga tttaatgctg gataatcgat
     1501 gagctatcat aataactgtt ttttctttca tcagatgttg aaaagccttt tgtagttcat
     1561 actcattatc tggatcaata gatgcactgg cttcatccat aataacaatc tttgcatctt
     1621 ttaaaattgc tctggcaata gctatacgtt gtttttctcc tcctgacaga taaactcctt
     1681 tactaccaat taaggtatgc tctctttcgg gaaatttttc taaaatcgat tcgcaaccgg
     1741 ctaatcttag cgcgtcaaat actttacttg ctggcgcttg aggatttgct atagaaacgt
     1801 tatcgtaaat actctgattg aatagtttcg tatcttgaaa gacaaaagca attgtgttaa
     1861 taattgtgtc ttttgaatag tgatttaaag gcttaccacc aattttaatc tgtcccttat
     1921 ccacattgta gaaacctgaa attagtttag ctatcgtact ctttccgctt cctgattttc
     1981 ctactaatgc ataaattctt ttttgttcta aaactaagtt gaaattttct aaaacacact
     2041 cttctttgta tgaaaagctg acattttcaa atgcaatgtc acaattttta atctgtgtct
     2101 cgttcccata ttttagttgg tcttgcttca tttctaaata aagggagtct agtgtttcga
     2161 ctgcatatct tgcttcaaac aagtgcatac ttacatacat tattctcatg aaagaaacaa
     2221 aaataattcc acttaaaaaa aacaacatca acaagtcaac agctaatatc ttgggagtgg
     2281 taagagaagt tataaaaaag gttataggaa ctatcaaaat gcaaactatg ccaaaaaata
     2341 gccattgaaa aagaacaaaa ggtgttttcc cactcaaaga atacttatat gcaaacttag
     2401 cataatcgtt aattgcttta ttcaaggctt taaatgatgt tactttagca ccaaatatct
     2461 ttataacttg aattcctcgg atatattcta ccgtttcaga gcttaacaca tctaacgatt
     2521 cttgatattt ttgaataaaa tttgtattct ctgtcatttt ctttaacaag aatacaccaa
     2581 ttactaacat ggcgattaga accaatccaa ttttaaaatt aatgaaaaag cctaaggcaa
     2641 ctgataaaac aggtgttact atggcttgag cactatctgg aatcaagtga gcaattgcca
     2701 tatgtgtttt agccgcgttg tcatcaattg tctttcgaat atatcccgaa gaatttaaat
     2761 caaaaaaacg aaaacttgct tctgttaaac cgctaattcc cttttttctc aaattagtct
     2821 ctaagcgaaa cccaaggata tgagaaaata agccagaaaa aatataaaat aaagctccta
     2881 aagttaacca agcaacagtt tgaaccgcat aactcttagc taaatattca tctcctacaa
     2941 taattagaga cttaagaaat ttgtaaatac tgtaatatcc atagactgtt aatacgacag
     3001 aaaaatcaga aaataaagtg gctaaccatc cgtagtattt cattttaggg acataactaa
     3061 ataatttttt gtatactttc attttttcct cccccgcatt caatttcttc tcttattcgt
     3121 ttacaactgt taatgctttc cgtaatagcg taaattagag atgtacaaac agatagaagg
     3181 taaactacgt tctatttttt gtattttttt aagacttttc ttccaatcaa tacaccaatc
     3241 atagataaac ttgctacaac taacactgaa atgattcccc atatacctac cgcatagtgg
     3301 atcattgcat ccattgttgc agcagattgt cctttatcta tccaatcttg acgaaaacga
     3361 tctgtaaaga accatatagg aatccactgt ccggcagcac tgcctaattg cattagagcc
     3421 caagacgcaa cttgaggaat tgctcgatca tatccaaata cagatagaat aatatcagct
     3481 aagatcgcca tactaatcga actgataaac caaggtaagt acgccccgcc cattaacgta
     3541 aaaaataaca ataaaacaat tgtgtaaata gtaaaaattc cttttctagg gtagttatag
     3601 ctaatataaa caaatatgat tccagataat aatccaaaaa tccctgggga tatgctgtga
     3661 ccaaacgccc caccaatact actaaccatt attgaaaaaa agtaaattac tagggaaata
     3721 actgtagcta aaccaataaa aatataatct tttgttttca tatatattct cctcaattct
     3781 atttcgttat gtcattaaaa atctgttcta tcaaagttga atcttctact ctaagtttta
     3841 tatctttttt tattccacca ttttttaaat aaataattct attgcatgtt ttataaagaa
     3901 attccggatc atgagtggct ataactactg cacccttttc ttttaagtct ttaataaggt
     3961 cagcaatcct ttccatatta atataatcca acccacttgt aggttcatca aatagaaata
     4021 aattagtttt tgacaatgaa gctatagaaa ccaataatct ttgtttttct ccaccggata
     4081 aatcaaacgg taattgatct ttcattttat aaagttccat tttttttaaa attttttctt
     4141 gctgatcttt actaactatt tcattcccca gggctaactc gctcctcact gattctgtga
     4201 aaaattggta atccatttct tgcattacta aaaacggcga tgacaaattt tttttatttt
     4261 cgattatctt tcctttggta gggcgaataa tcttcatgag tattcttagt aaggttgttt
     4321 tccccacacc gtttttccct accaaaccaa taacatctcc aactttgaca tcaaaattta
     4381 tgtcttttag aatattttca taagtaattt cttcaacttt taatacatct gcacttacct
     4441 tttcgatata gggaacttca atcgaactat taaaaatgtc aaatttcctt aatgcgttat
     4501 tgttttcagt ttttaacaac tgaatagttg tagtttttac agttctattt ttaacaaata
     4561 gaacttgatc aattaattct ttcaaatagt aaaaacgatg ttcagctata acaatagtaa
     4621 atcctttatt ttttaaatca caaagtaagt cagcaagttt cttagtcgct ttgaagtcca
     4681 aatttgaaga cggttcatcc aatataatta atttagagtt tagcgataaa ctacatccaa
     4741 tagaaatttt ctgccgttca ccacttgata gcgaaaaaat gtttttatct aatatatttg
     4801 aaagatctaa taattcagct aattcattga ttcttttatc catatgctct tttgtaaatc
     4861 caaagttttc catcgaaaat actaactcac tcgttgtatt tgttgtaaag aattgtcctc
     4921 taggatcttg acttacgtag ccaatatttt ttgatatact ttcttgtgtt aaggattgta
     4981 gcgagttatt ttcaaataaa atttccccaa ccaattttcc gtcataaagt cttggaataa
     5041 gtccattcat taactttaat agtgtggatt tcccactccc agaagaacca gtaatcaatg
     5101 taagactacc tttttttatt gaaaaattaa ggtcaacaag cgcttgttcc ttaacatcct
     5161 tatatgaaaa agaaacattg ttaaattcaa acaattcttt cacctcaaat caaaatactt
     5221 aagaaaaaaa tagtaacgga aaacaggatg atatagtcta ataagctcat gtttgtttta
     5281 tagtaagaac ttcttttcac aggagattct atcccctttg ttattgcatt agcggtcatt
     5341 tcttcagcaa tcatagttgc acgtataaga acgggaacta acagaaattc caaatattgc
     5401 agaggctgaa aaaaagacaa gcgaatgttt ctcattttta aagattcttt aatcattctt
     5461 atttcagaac gataagtcgg aaagaatctg atcactactg taatacttaa cattattttt
     5521 ttcggtaaat gtattttttc taaagaggat aataattcat tgctagtata gacactaacc
     5581 aacaaccatg agatcattac gaccggcaac attcgaaata caatatataa ggatgtccca
     5641 aaaaatatag taaaaaactc tatcttgata gcatcaataa ttttcattac taaaaacaga
     5701 actgaataaa tcaagatgaa ataaatacat gtctttattt tacgaaacat caatactaaa
     5761 actgtagcaa taatgaaaca ccccacttga aatatatttc cctttcctaa aaaaataatg
     5821 accggaaaaa aaatatttaa agtaatcaag gttaacggat tgatttttga cactctttca
     5881 cctccaaaaa ataagatcgc actgttatct taagctgata aaaatgcacc gttattcaga
     5941 taacagtgcg atcttatcaa aaagcataac tgagaacaat tctcaatgca agcttttttt
     6001 taattaactc agtaattcaa tccacccagg aacagaaaat tgatacaatc ttctggttaa
     6061 tagcatagtc ttttcttttg aatagctatg cttcaatata tcatagaatg tagcgtagaa
     6121 tgagtaaatg tagaagtgga tttcttcttc attaaagact aaattttgat tgatcattcc
     6181 gatagtcttt aacttatcta gacaacagac tgtctttttt gtcacaaatg atgtaatttt
     6241 ttcaacaata tcttgatatt tggttccagc tgattggaat aaaaccaaat cgaatatacg
     6301 tttattctca aaaatataat taataaatgg atctaattca ttgaagttct ctctccaact
     6361 tttctctata tctatatttt ctaagtttaa gaggtatttg gtaaactctt cattatacat
     6421 attaataagc gcattaatat gcggctgaat aatttcttca aataacgctt ccttagaagt
     6481 aaaatgttta taaaaagcac ccgtagttac gcctgcggtc aagcacagtt gccttatctt
     6541 agtttgctga aatcctactt tttcaaaatg gcttagtcca ctttctatta atttttggtg
     6601 agttgtaata taatctctgg tttctatggg tacttcctcc taataagatg aattaactat
     6661 attatcttac acaggacttg aagtttcaat cgttaacgtc tattactgaa ctcattcctt
     6721 agagctaaac taatgagaaa gagcaaaata actgatacaa aaagcaatcc tacaagaatt
     6781 aatagactca tctaaatcat tcaccttttc taaaataatc cgagaaagat ttaaaaaaat
     6841 tatatccagc tattaggata agtcctatca taatcactcc aatagccatt ttcttatcct
     6901 ccctaaaaat aaagcctttt acttaaaacc tttttttgta atcgtcaata aattttttcc
     6961 ctttatcagt taattgaaat cctatatcta aatagtcctc atatctaagt ttagtcagca
     7021 tctcacttac agatgctgga ctaacactta gaacttttgc taaatcatta ttttttaatt
     7081 tcttttttct ttttgataat tcctgaattg ctagtaaata aattagtata gtagttgttt
     7141 taatttgtac catacctacc ctccaaatta tttcgaaagg ccttcagcaa ttttatccag
     7201 gttccatttc atcatcgcat agtaactatc accatcttgt cctttttctg caattgaatc
     7261 agtaaaaatc gttgaataga taggaatatt ggtatctttt gatactgttt tcattggtct
     7321 atcgtccaca ctgctttcta cgaataagga gggaactttt gttgtgcgta atttttcaac
     7381 taagtgtttt atttgatctg gtgttccttc ttcttcagtg ttgatttccc aaatgtaagc
     7441 agaaggcaca ttatacgctt tcgagaaata tttaaagcat ccttcacttg taacaatcat
     7501 ttttttatca ttcggaattg aagcaaattt agatttagct tctttgtcta gagaatccaa
     7561 tttttcaata tacttatcta gattttcttt atagaatttt ttattatcag gatctttttc
     7621 cgctaactgt ttttcaatat ttttagcgta aataataccg ttttctaaat ttaaccaagc
     7681 atggggatct tccttccctt tctcactctg accctctaag taaataacat ctatgccatc
     7741 acttgctgca aaatagtctt tgttttcctc tttgttcgca ttttttacta attttgtaaa
     7801 ccaagcattt cctccagttt ccaagttaac accgttataa aaaatcaaat ctgcttttga
     7861 agttttttga acatcttcag gcaaaggttc atattcgtgg ggatctttcc caataggtac
     7921 gatactgtgt aaatcaattt tatcttttgc tatattttca gtaatatctg ctaaaatcga
     7981 attagtaact actaccttta atttttcgtt cgaagccact gtatctttgt ctttactatt
     8041 tgttgaacat gccccgaata taaaaagagc aatcaaaatc cccagacttc ccagtactgc
     8101 tttccatttt ctcatcataa ctttctctcc ttctttctta aaaatttttg ttttggtgag
     8161 attagaaaac taattacaaa taagaatgcc gctgttaaaa caatacttga tcctgctgct
     8221 atgttaaaac tataaccaat gaacaaacct agcaatgatg agcacgctcc gactgtcgcc
     8281 gaaataaata tcatagtttt taaactgttt gcatataaat atgctgtagc agctggtgta
     8341 attaacattg caacaattaa tatagttccc acactttgca tagctgttac tgctactaaa
     8401 gttaatagaa tcattaatag ataatgataa aaactgacat tcatccccat tgcttttgcc
     8461 attaatggat caaaagaagt gattaataat tctttaaaaa atagaacaac tgtaaccaac
     8521 actaaaacag aaacgccaat tgtaatccac ttatcaatat cttgtacagc taaaatattt
     8581 ccaaataaga tatgaaataa atccgttgag ctatttgcaa ctcctataag gataactcct
     8641 aatgctaaaa aagaactgaa agtaatacca attgctgtat ctccttttat tacactattg
     8701 ctttttataa aagtaataat gatagaagct aatagaccaa atacaatcgc accaataaaa
     8761 aaattaatac ctaaaatata agaaattgct actcctggca aaacagcatg agaaatagca
     8821 tcacccataa gagacattcc tcttaaaata ataaaacaac ctactgttcc agaaacaatc
     8881 cctataacta cagatgtaat tagagcattc tgtaaaaagt gaaagtcata cagaccatta
     8941 ataaaatttt gaagcatatt attccccttg tatattagag ttagggtttt aaccttccgg
     9001 ttttgattgg ataaccctat gaaccatcgt tattttaatt tggtattaac tcatttcttt
     9061 tgagataata tatttattgg attgagaggc taagccgttc ccccctctcc aataaatata
     9121 gtatctccat aggctttttt taaattctct tcattaaata cagattctac acttccgtga
     9181 gcaattagat ttcgattcaa aagaataata ttatcaaaat acttctttac cttgcttaaa
     9241 tcatgatgca caattagcac tgtttttccc tgatgtttca attcttttaa cgtatccata
     9301 attattcgtt cactaactaa gtctatccct acaaatggtt catctaaaaa tatgaaatcc
     9361 gcattttgag caagacatct tgctaaaagt acacgttgaa attgtcctcc agataattct
     9421 cctatttgat gattagaata ttttcccata tcgacctttt ccaaagcctt tgaaactctt
     9481 tgccattctg catttttaat tctttgaaaa actttcattc cggcatatgt tcccatagat
     9541 acacattctt ttacttttat tggaaaagta aaatcaatat cagctttttg ctctacatat
     9601 gcaatcttca ccagtttttt attgatatct tcattattaa tggagacctc tccctgatga
     9661 gggataatat ttaacattgc tttaagcaat gtagattttc cagcaccatt tggaccaata
     9721 atacctgtta aagcaccttc ttgtattttt aaagaaatct cgttcaatgc taaaaaatcg
     9781 ttataacaaa cattaagctt tttcacttct aacataactt tctccttcta aatgataatg
     9841 attatcacga tcatatggta tacaaaaatt atattttagt caaccctaaa ttttataatt
     9901 tagatttttt tctgttgttg aagattagga tgtcaaaatt atttgaaact actcgtatag
     9961 taaatagtaa gtaattttca aaacacgaag aaaaacaaaa agaaaaaagg aaacgccgaa
    10021 gcatttcctt tcagtgattt aatgagaaca acacgatttg acttagagtc tcaaaaagtc
    10081 gaataggtac actcatttaa gtgtctccat tcgacttttt ggggatgagc tggctattga
    10141 ggtccgctta ccctattgaa taaatacaag attgggtatt tctaataagt ccgcccttca
    10201 tattggggtg atcggggcga acatgccatc ttttcatata ccacctcctc gacactcaat
    10261 aatcaaagat tctcgttaat cttcttcgat gcttgcaatg atgttttcaa tattcatata
    10321 acgaaaatct tcttgtttga tataaacgat ctgagcggta catttttcct ttttgatgat
    10381 ttcttttact ttttcctcag aacgtgcgac ctgcggcgtt aaaagtaaaa cgtcatagtc
    10441 tttataattc agtttttctt caacgtttcg gatcgttgca taatctatct catacgatag
    10501 atttttggct ctgatcgttt caagcatttt tgatacgagc agcgacgcac tgattccggt
    10561 ctcgcaaata atcaatagat ccttatgcat aataccctcc tgtttttagc ctgcaaagcc
    10621 aattggtgaa aatgccacat aagttaaaat aacaatgact accaatgcta tagcagtcac
    10681 cttggtgtat ttccaaggct cgatatcgac ctttgtatcg aatgagttca acacaaattc
    10741 tccatcaggt ttcaatttgg aaaccaccat caaaatgata atgtccagaa cgaataatgc
    10801 cgtcaaaaca taaaggaaat ggatattttg gaaaagcatt tttgatagtg catacaagac
    10861 gatatgcacg gcaatcgtcg tttttgcccc aaaagcagtt gctttttttg aataaaaggc
    10921 aaagagaatg atcacgagca gcggcatgtt gtatagtcca ttgaattctt gaacgaactg
    10981 atacaatcca gccggtgcaa aagaaatgaa tggcgctacg ataatggaga taatccccac
    11041 aacgaccgtt actgttttac cagcacgagc gatttgctta tcatttgctt tcttattgat
    11101 aagcggttta taaaaatcca gtgaaaacaa ggtcgatgtc gcgttcaaag ctcccgcaaa
    11161 tgatgataag atcgcgccaa agataacagc ggcgaaaata ccaaagatca ttttaggcaa
    11221 tacttcactg actaaaaaag gatacgcgtt atctggattt gacattaaac tatcgccaaa
    11281 aatattgcga gcgacgatcc ctggaaagac aaggaataac gcacctaaga ttttgaagac
    11341 gccgactagg aaagcgccct tttgtgcctc agctaaattc ttgccggaca atgctttttg
    11401 gacgatcatt tgattggtac accagaaata cagattgtta aacagcatcc ctgtaaatag
    11461 tgtcggccat ggaacaacag ccgagtcgat cgatcccaca gagttaagca gccatggcgt
    11521 gtttaccaca acgtgttcga tcccgccaac aaagctgccg tcaccaagct tcattaagcc
    11581 taaaattggg accagcagac cacaagccag cagaccgact ccataaatgg agtcactatt
    11641 ggcacttaac gacaagccgc cgatcagcag atagaggatg ccgacaatac caattgccat
    11701 cgctacaatt atgatcgcga cgatcggctg gacgcccagc agctcatcaa tatggaagat
    11761 cttattgaac accagcgatc cagaataaag aaccacgggt aagaaagaag tcatataggt
    11821 cacaataaat aagatcgaaa taattcgttt ggtaaccgta tcataacgaa tctcgatgaa
    11881 atctgagatt gtattgatgc cgtatttaaa atattttggc aagaatatca cagccaaagc
    11941 tacgatcgca atcgtagcag ttacttccca ggccattact tccatccctg catgataact
    12001 ttgaccattt tgtccgacta tttgttcggt ggacaggttc gtcatgatga tcgtgccggc
    12061 gattggcaaa gcagttaagc tccgccctcc catgaagaac ccttctgatc cagaagtatc
    12121 gacacttctg gatctagaat aggcaaataa ccatacacag atgacaatca ctaggaaact
    12181 gattatagaa aaaagattca tcgtctagct ccttttcaat agattaaaga ccggtgacct
    12241 ctcgaatgta gcttctggct ttgactgcat attcaaatgg attggcttta gccgggtcct
    12301 gttctgcttc aactacgatc cagccttcat agtcgctggc atggattgct gtccagattg
    12361 gagtgaaatc aatcatccca tcaccaggaa ccgtgaagac gcctttcttc acgccgttta
    12421 agaagctgtc tttttccttt tctacttctt cagccgtttc ttgacgaata tctttgaaat
    12481 ggatgtgttt gatacgatct tgatgacggt tgtaaaccgc gattggattt tcaccagaaa
    12541 agaccaaatg tcccgtatcg aacaataatt taactttgtc tggatcagtc atttccatta
    12601 aacgatcgat ttcttccgtc gtttgaacgc cggtacccat gtgatgatgg taaacgatct
    12661 ccatatcctt ttcgtgggcc aaatccccta atttttctaa tccttccgcc agttttttcc
    12721 actcttcatc agtgaaaact ggtttatcat caaagactgg cgctgtcata atcccttgga
    12781 tactatgacc ctgctcagct actacgatga ctttagcgcc catcgcatgt aagaaatccc
    12841 gatgtgcttt gaaggcttcg gcagtttctt caaaaggttt agttgtcaga aacgcactga
    12901 accatgcact ggcaaccttt aagccgcgaa tattcaaata ttgttccaac acctctggat
    12961 cttttggata tttgttgcca atctctgttc cggtgaaccc agcaagggcc atttcactga
    13021 tacattgttc aaaggtattt tcactaccaa gctcgggcat atcatcattg gtccacgcga
    13081 ttggtgcgat ggctaattga atttgtttgg tcatattctc acactcctgc ttattttttt
    13141 agttgtacta aactcttcgt atcgaatgat tcttgacaag ccaacgcgat cttagttgat
    13201 tgcaatccat cttctgcatt aaccgctggt tgacgttttt cttgaataca tgagacaaat
    13261 tcttgggctt cacgaatgaa ggcttctctg aatcgttctg ggaagttttg tgaacatgga
    13321 cggatgatcc cttgatcgtt catgatcgtc acaagatttt tctcaggcgc ttgcgctacc
    13381 cgcagcattc ctttggttcc catgatctct gtttcgacat gatagccatg ggctgcgttt
    13441 ctgccggcaa ctagtaaagc tattgtttta tcgctcaggc tcatcattgc ggctccagtt
    13501 tcaagctcac cagcctgatc caattctgga tacgccgcat ttttcccaat cgcccacact
    13561 tgatcgactt cttggccggt aaaccagcga accaaatcaa tatcatggat cgccatatct
    13621 aagaacaagc cgccgctgtc gttattcatg gcaaatttga caaagctttc caagccttcg
    13681 ctcggatcga tcccataaca acgaatcagt gtgatttcgc cgatttcgcc atcttctacc
    13741 attttcttcg catactgata cgactcatca tagcggcgca tgaagcctaa catgaagacc
    13801 tgttcaggat gctcttcgat gactttttgg gtctttttaa tatcttcaac ttcaaggcct
    13861 aatggttttt cagtaaagac atgcttgcca ttttccatcg ccaagcggac ttggtcacag
    13921 tgaaagcctg atggtgaaac aataaagact gcatcgatca cggaactttt gaccatttct
    13981 tcatagctgg aaaaagtatg cttgacgcct aatttcttct gtgcgaatgc taattctgtt
    14041 tcaactaaac tgcacgcagc cgtaagctca caacaactga cacctgttgc taaattttgt
    14101 gcatgtactt ttcctaatct tcctaaaccg acgatgccta ctctaatgtt gttcatgaaa
    14161 tacctccgtt ttctgagaat tactcattgt atagtgctgg tcgttcatcc atttgaatca
    14221 ttacttttgt ttttgtttca cgagactcat gacaagccat catggtgatc gctgctacat
    14281 acccatccca agcggtagga ccgacaaccg catcattttt gatcgaatcg atccacagct
    14341 tgaattcata atcataggca tccaaaaagc gggtctgcca atctggtgaa acaggtgtgt
    14401 aatttttttc ttccgattta attcgtgtat aggctgggtc cgtcattcct acttctgccg
    14461 tttcgaaaac cacatcacat ttaatatcgt agccaaagcg gcaattcaca aagatttcca
    14521 aatcaatcgt tacaccggat tttgtttgaa agatcagcag ctgcggatca tgcaaatcgg
    14581 catgggagtt gctggttttt ttcggcaaga tcatttgaac agattcataa tcttcattta
    14641 gcaaccagcg aagcacatca atctcatgaa tcgcggtgtt gctgatcgcc atcggtgttg
    14701 tgtagttttc atctgcgcta ggatttctat gggcacaatg catcattaat gcttctccgt
    14761 attgcttcga ttcgattgct tctttcagtt caatgtagcc gcggtcatag cggcgcatga
    14821 agccaacctg aaccaatttc ttcccataag caacttccgc atcaacgatc cggcggcagc
    14881 ctgctgcatc catcgctaat ggcttttcgc agaaaacata tttcccatgc ttgattgctt
    14941 ctaacacata ctgctcatgg gtcgggtccc aagaagtcac aacaacgaca tccacatctt
    15001 cagaagcgat caatgcttct ccggtttcaa agaatttagc atcgacacgt ttggcaacct
    15061 ctttagcagc ttttacattg atatctgaga ctgctgtcac ataagcccct tgtgttttct
    15121 gattgatcct gtcgatatgc tcgatgccga ttgcacctgt tccgataacg cctactttta
    15181 ctctcaatta cttatccccc tgttctgttg tttaagcaca catagtatgc gcttacaaaa
    15241 ttattcctgt gtagctttta ttcttaaaag gtagagccct ctctttgctc cgccttttac
    15301 tacccataag cttgtacgta taattcctta atttgactat gactaggcac ctttttatta
    15361 ttttgcggac ttccgctggt caacgcatcc gcggccattt tgtctaaggc tgccataaac
    15421 gcttgctgat caataccata atctcgaatc gttgggatcg acagctgctc acagagctct
    15481 tggatttttt taatcagata atccgcagcc tcttccagcg ataaatcttc ggctgccgga
    15541 taaataaatc tggcgatcgt cgctaactca gtctgaatag catcctttga gaattcaaaa
    15601 aagaccggca ataacatcgc atttgatatc ccatgaggaa tgtgaaaaag tgcccccacc
    15661 ggtcgactca ttccatgaat caatgtgact gacgcattcg aaaaggcaat ccccgcctcc
    15721 gttgaagcta agctcatttg ttctctggct tcagtgtcgt cgctattttc atatgcctga
    15781 gaaagcgtgt tcaaaatttt cttcatcgct tccagtgaaa atagttgcgt tacttcattg
    15841 gctttgactg aaacataaga ttccaaagcg tgacatagcg catcgactcc cgttgccgcg
    15901 gttacttttg gtggtacagt tttcgtaaaa tcagagtcaa cgattgagat ctgtggcatg
    15961 aaaacgagat ccttcatcat cattttgact gctgtttttg tattggtaat aactgccaca
    16021 tcggttactt ccgaaccagt tccagcagtt gttgacactg caatcagcgg aatgcccgct
    16081 tgcagctgat caaaatttct tgcatgaatc gcttcgagac ttaattgatt agcagccaaa
    16141 acggctacca ccttggctgt atccagacag ctgccgccac caaaagcaat gatatgatca
    16201 cattgatgct tctgaaaaag cttcagcgca tcataaacat tttcttgcgt cggttcggct
    16261 tgaatgtctg tatactccgc taattgatca tctgtttttc ccaacagctc cttgatcttt
    16321 tgaagatgcc cggtctgttc cataaccgta tcactaatga ttaacggctt gttgcctagt
    16381 tgttctgatt cttccataag aaattggatt gttccgccgc caattcttaa attggcaggc
    16441 attttcagtt gaatattcac agaaaaaacc tctctctggc ttatagccta taacagaatc
    16501 ctcgaagctc tttaacagag cttcgaagca aatctttaaa tctcactttg cgcataacgt
    16561 gctgtaacaa ctttccgatg ggtataaaac tcaacactgt ctttgccatt ggcatgcaaa
    16621 tcaccaaaga aagagtgctt ccagcctgaa aaggcaaacc aagccatcgg tgcaggcacc
    16681 ccaagattga cccccagcat cccagcatca acattttctc tgaagtagcg aatcgctgat
    16741 gcgttgttgg tatacagaca cgaaccattc gcaaattcag attcattcgt cagctcaacg
    16801 gctgccatca aatcttttac ccgcacgatt gatgcgaccg gggcaaaaat ctcatcctgc
    16861 cagatcttca tatccatcgt gacattatca aaaatcgttg gtccaacaaa atagcctttt
    16921 tctggaatgt tttcgcgacc atctagtacc agtttcgctc cttcatcgac ccctttttgg
    16981 atatagtcaa aggtccgctg ctgtgcatct tttcgaatca ctggtcctaa aaagacccct
    17041 tcgtccaagc cattgccgat cttgatcgct tttgccgcag ccttaaattt ttcaacaaac
    17101 tgatccgcga tttcctcttc caaaacaatg acggaggctg ccatgcagcg ttcaccagca
    17161 gaaccaaaag ctccgccaat aaggtccttg actgcccgat caatattggc atctttcagc
    17221 acaacaacat gatttttcgc tccagtcaac gcttgtaccc gttttagatt ttttgttcct
    17281 tcacggtaaa cgtattcacc gacatttttt gatcctacaa agctgatgcc ttttaccagt
    17341 ggatcttgca gcaatgtgtt gacaacatcg tgggcaccat agacaacatt aaaaacaccg
    17401 ctaggaaagc ctgctttttc aaccagctca acaattttct ccatcaacaa tggtgttttt
    17461 tctgaaggct tcagcaccac cgtatttcct gccgccagag ccatcgggaa gatccagaag
    17521 ggcaccatca ttggaaaatt aaacggtgtg atccctccga ttactccgat tgggtaacga
    17581 taattcgtga tctcaatatc agtcgccgct gttgataaag aatctcccat cattaaattg
    17641 gtgattcccg ctgcgtgctc cacattttcg attcctcgtt gaacttctcc cagtgactcg
    17701 gacaatgatt tcccattttc cagcgtgatc aaacgcgcca attcactttt atgatctgtt
    17761 aaaagctgat gcagcttgaa cagataacgt ccgcgaacag gaacaggaac ttttttccaa
    17821 gtttgaaacg cagcatcggc agctttaact gcttcggctg tctctgcttt gctagacaac
    17881 ggtacattcg ccagcgcttc ttctgtagcc ggattcatta cttcttcaaa ctctgttgag
    17941 cgactagcga cccaacgacc atcaatataa tttcttaaaa atcttgtcat tta
//
LOCUS       DADGHT010000058        17377 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.058, whole genome shotgun sequence.
ACCESSION   DADGHT010000058 DADGHT010000000
VERSION     DADGHT010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17377
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.058"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(540..1565)
                     /locus_tag="JX887_001790"
     CDS             complement(540..1565)
                     /locus_tag="JX887_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1257773.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            1840..3525
                     /locus_tag="JX887_001791"
     CDS             1840..3525
                     /locus_tag="JX887_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAX1257774.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            3539..4822
                     /locus_tag="JX887_001792"
     CDS             3539..4822
                     /locus_tag="JX887_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAX1257775.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            4892..5761
                     /locus_tag="JX887_001793"
     CDS             4892..5761
                     /locus_tag="JX887_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1257776.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            5758..6594
                     /locus_tag="JX887_001794"
     CDS             5758..6594
                     /locus_tag="JX887_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1257777.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            6620..7687
                     /locus_tag="JX887_001795"
     CDS             6620..7687
                     /locus_tag="JX887_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAX1257778.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            7684..8511
                     /locus_tag="JX887_001796"
     CDS             7684..8511
                     /locus_tag="JX887_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAX1257779.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            8556..9581
                     /locus_tag="JX887_001797"
     CDS             8556..9581
                     /locus_tag="JX887_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1257780.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            9578..11761
                     /locus_tag="JX887_001798"
     CDS             9578..11761
                     /locus_tag="JX887_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAX1257781.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            11761..12889
                     /locus_tag="JX887_001799"
                     /pseudo
     CDS             11761..12889
                     /locus_tag="JX887_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            12886..13563
                     /gene="pgmB"
                     /locus_tag="JX887_001800"
     CDS             12886..13563
                     /gene="pgmB"
                     /locus_tag="JX887_001800"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAX1257782.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            13647..14174
                     /gene="msrA"
                     /locus_tag="JX887_001801"
     CDS             13647..14174
                     /gene="msrA"
                     /locus_tag="JX887_001801"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAX1257783.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14375..15061)
                     /locus_tag="JX887_001802"
     CDS             complement(14375..15061)
                     /locus_tag="JX887_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAX1257784.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            15141..16679
                     /locus_tag="JX887_001803"
     CDS             15141..16679
                     /locus_tag="JX887_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAX1257785.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            16799..17266
                     /locus_tag="JX887_001804"
     CDS             16799..17266
                     /locus_tag="JX887_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAX1257786.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
BASE COUNT         5637 a         3143 c         3755 g         4842 t
ORIGIN      
        1 tctaaaataa tttgtctaac tagaagaaaa gtgggaaagg atcttaacaa catcggttcg
       61 tatccaatta aggtatcgga acgatcatct tccaagagaa gtcaatcaac aaaagtaaag
      121 atagatcatt ttttgaatgc aaaataaatt gatgggaaga tagagcggtt atttttaata
      181 ttttgctagc tattattgaa taattcctcg aataaaacaa aaccagtaga catgtctgtt
      241 attctattta tgttttagag ataagtatcc ccaaataaca tggattgaaa taagggtaaa
      301 tgtgtttaaa aaaacgaact ataaaaactt atacacaacg tggttaaaaa tagttttttc
      361 ttccctgtgg aaaaaatagt ttaacacaaa cattatagtt atccacagct atctaaaaca
      421 gatggaaaat aagaaaaatt cgctaaaata ccgggagggg gtaacgaggg atgagtgatt
      481 gaaaaaagaa cagagtaact gacttatcct cagtgtttct gttcttttat aattctgttc
      541 tacatttctt gttgttggat cgaatctgtg agagtaatct cggttgaaag aatgattctt
      601 ttttcttcag ggtattggtg gtggattagt tggaataaaa gttctgtggc tttgattcct
      661 aactgatttg tcggaatgtc tatccgagtc aactgtggcg aaaataggga ggacaataag
      721 ggatcactga atcctgcgat cgaaagatca tcaggtatct gctttccaga ttgttctgcc
      781 actttgtaaa tactcaatga ttttaatgca tcggtagaaa aaatcgcagt tggtctttct
      841 cgtagcttca ttaaatcatt cattgctgcc atgctatctt ctaagcgaaa gccgccgtct
      901 ataatccatt cattacggat atctaggtgg tgatcaaata agcattgacg gtaaccattg
      961 agacgatcat tggatacata aacttctgtc ggagcatgga gacagccgat atgacggtgt
     1021 ccattcttga tcagtgtttc caccaaatcg taactatcct ggaaattatc cgtgtccact
     1081 gagtagatgt tcgtgtagtc gtttccgact tttccgatta ccacaatagg aatattgtat
     1141 tgatccaatt caaaaagaag tgtttcatcc atcgtagagc ttaaaataat aattcctcgg
     1201 atcatttttt cttggatctt tttcgcgcat ttttctagct cttcttctgg tgtttttgcc
     1261 gtttgtagaa tcaagtcgaa gttattttgt tcagaaacgg cagaaatgga ttgaataaca
     1321 tctgaaaaaa aaggattgcc ataggtcgta tgagaagtac gatgagataa tgctagaatc
     1381 gcgtcaaaac catttcctga cagtcctctt gcaattttgc tcggttcata attcaattct
     1441 ttgattgctt gaagtacact tgcttttgct ttatcagaga tatttggctg gttatttaat
     1501 actctggaga cagttgattt tgagacatta gcttttttcg caatgtcata aatagtaggt
     1561 ttcaatttta tatgcacctc ctttttggga gcgttttaga ataattccat agtacaatag
     1621 acattctttt ttgtctatga ttttgaaaat ttaggaatag cttgcatgat catgagagac
     1681 catatttttt taagaagcta ttaattattg atacataagc tttcttattt gtatttttgt
     1741 gtatatcaaa attatttaaa aaaatgctat tgacagtaag cgttttccat aatatgatca
     1801 aatcgttggg aacgctccca aaaaagaaag gggaatccga tgtatacaaa acttttacaa
     1861 gcgatttatc gcgactcaga tttgtctgag aaaaccgcct ctatgattga acaaaaagtc
     1921 agtgtttatc agcagaagaa aggccaggca ggcaaactgc attgggacga agaagatatt
     1981 ttcttgatta cttatgggga tcaatttttt gaagagcagc aaccaacttt gcgtacattt
     2041 aagaaatttt atcaaaagta tttggcagat acatttagag ttgtacattt cttgccattt
     2101 ttcccatata catctgatga tggtttctcc gttgtaaatt atcaggcaat caacgaccgt
     2161 ttgggcacat gggaagatat agaagaaatg agaagcgaaa cacggttaat gttcgacttt
     2221 gtctgcaatc atatgtctgc cgaaagtact tggtttcagg aatatttaaa cttgaatgat
     2281 acgtacaaag atttttttat tgatttgcca ctggatacag atacaagcag cgtgactaga
     2341 ccaaggacca gcccgttact tacaacgttc attgacaaaa acgggaaaga aaaacacgta
     2401 tggacgactt ttagcgaaga tcaagtagac ttgaatttta aaaatccaga agttttattg
     2461 aaaatgatcg atattctttt gttttactta gaaaaaggcg cttcatttat tcgcttggac
     2521 gctgtgggat ttttatggaa agaactagga acttcttgta tacacctgcc agaaacgcat
     2581 aaaatcatcc aattattccg tgcaatcgct gatgaagcag ctccaggaac ggtattgatc
     2641 actgagacaa atgtgccaca caaagataat atcagttatt ttgggaatgg cgagaatgaa
     2701 gcacagatgg tctatcagtt ttcgctacca cctttgaccc ttcaagcgat tcgttcgggt
     2761 aatacaagta agttgaaaga atggttaaaa accatcgatt tcgcatcgaa aaaaacaact
     2821 ttttttaatt ttttagcctc ccatgacggt atcggattga atccggtacg aggtattctg
     2881 ccggaaaaaa cgatccttga attagtggaa cagctgaaga aagagggtgc ccgagtaaac
     2941 tacaagaaaa acccagatgg aacgaccagt ccatatgaga taaacgctac gtatctagat
     3001 gcgttaagtt ctccaacaga tacgacggaa tggagaagca aacgcttttt agctgctcat
     3061 tcatttttgg taacgttacc aggcgtgccg gcaatttata ttcaaagtgt gctgggaagt
     3121 cgaaatgatt acaaaggcgt agaaaaaaca ggagagaatc gaaaaatcaa tcggcaaaaa
     3181 tttttgttag cagatattga gaaagagttg cagacagatc cattaagaac agcagtatat
     3241 ggtgaattga cccagatgct atctattcga aaaaaagaaa aagccttcca tccgaatagt
     3301 ttgatttact tactggactc agcagattct tttatcagtt ttattcgcga agcgaaggaa
     3361 gagaaagtct tagttatcca taatttttcc aatcaatcag caggttatct tttaccaaaa
     3421 ggagattacc tagacctgtt ttctggacaa attatccatt gcagtcaaga acgaaagttg
     3481 atattccagc cgtatgaata tatgtggctg aaaataataa aataagaggt ggaaaaaaat
     3541 gaaaaaaatt attgttacta cctgtctgct agctactgga tttcttctta ctgcttgtgg
     3601 tgaaagtcaa agctctaacg aatcacaaca gacaacgatt caattcatgc actcttctgt
     3661 cgaacaggaa cgattaagtg tgatcaatga actggttgct gattttgaaa aagaaaatcc
     3721 agacatcaaa atcaagcaag tgccggtaga agaatcagcg ttcaatacaa aaatcgttac
     3781 gttagctcgt tccggtaaat taccagaagt aatggaagtc agtcaggatt ttgctaaagt
     3841 gatggataaa gatgaactga ttgatcagac ggcagtccaa aacgttatcg aggaagctgg
     3901 agaagataat tattatgacg gagccaaaaa ccttgttcgt tcagaagatg gaaaaagcta
     3961 tattgctgca ccaattagcg gctgggttca aggtatttgg tatgacaaag aaaaattatc
     4021 agaagctggt ttttcagaac cagaaaattg ggatgatatt ttaaaaattg ctcaacattt
     4081 cacagataaa gagaataaac aatatggaat tgctatgcct actgctgaag gaacaatgag
     4141 tgagcaagcg ttctctcaat ttgctttgtc aaatggagca aatgttttgg atgatgaagg
     4201 cgaggtaacg atcgatacgg aaaagatgag agaagcattg tcgttttatc aaaacttatc
     4261 ccaatacacg atgccaggct ctaatgatgt gacagaaatc aaagatgctt tcatgaatgg
     4321 aacagcacca atggcaatct attcaactta cattttgcct tctgtttatg aagcggggaa
     4381 ctcagaaaat atcggttttg ctatcccaac acaaaaagat caagctgtct atggcacagt
     4441 atctggattg acgatttctt ctggtctaga cgagaaacaa aaagaggctg ctgaagcatt
     4501 cacagctttc ttatctcaac cgaaaaacat ggaaaagtgg gtcttgatgt ctcctggtgg
     4561 tgctcaacca gtgaataaac aagtagtcga actggatggt tacaaagaaa atgaagtcat
     4621 caagtctttt ggcgagctgc catctgagat tgctagtgct tttgatgaag tacaagtctt
     4681 tggactagtc ggggaaaaga atttcacgaa aatgggagat atcacaagct caggtgtgat
     4741 cggaaaagca gtgaaccaag taactgtcgg aaacgaagat gtcgatcaag ctttagctga
     4801 cgcacaaaaa aatacgaaat aacaagaagt tctgccaatg gtgttcgaaa aaagtagata
     4861 gctattggca gattatcagg gggaggtttc aatgaatcgt ccaaggaaac attctgactt
     4921 aaaattagcc atgggacttt tagcaccaag catgctttta ttagctgttt tagtgctgat
     4981 tccaatgctt tccaatattc agatcagttt tttcgatatg ccgctgaatc ctaactcaga
     5041 cgccgttttt atcggattaa gcaattatct tgaaatttta agtgatagtg aattttatcg
     5101 ttctttaggt ttaacagttg cttacacatt cttagttgta gcaggcagta cagctttagg
     5161 attagccgta gctattttgc ttaaccgcaa gttcagattt aggaaaacgg tgcgttcact
     5221 gattttatta agttatgtta cgccatctat ttctttgatt tttgcttgga aatatatgtt
     5281 caataatagt tatggaatcg tcaatgatct gttagtagat aggttgcagc ttttcaacga
     5341 agcaccgctg tggttcgacc agccagttgc tagcttcttt atggtcgttt tgtttgctat
     5401 ctggagatac tatccgtatg cgtttatttc atttttggct attttgcaaa cagtcgacaa
     5461 aacgctttat gaagcagctg aaatggacgg tgcaaatgct tggcagaagt tcaagatcgt
     5521 gacactgccg gcaatcaaac cagtactagc aactgtgatt gttttacgat ctatctggat
     5581 gttctatatg tttacagatg tctatctact gacgaataaa gtcaatatct taggcgttta
     5641 tttgtatcag acagcctttg cgttcaatga tcttggaaaa gcagcagcta tatcgattct
     5701 attgttcatc attattgcag cggtcgtctt gctctcacga aagaaggtgg acttgaaatg
     5761 aaaaataaaa agagcaggaa aatcttattt tacgcgacga ttttgttgct attagctgtc
     5821 aatttgtttc catttttgat catgctgatg acatcattca aggattcaca agaagcaatt
     5881 gcaacgacac aaactatttt tccgaaagaa tggacttttg aacattatca ggatattttc
     5941 aatgctgaga tttttccatt catcatgtat ttcaaaaata gtttagtgat ctccttgata
     6001 gcctccgtaa ctgcagtagt gattgggatc agcggggcat acgctttgtc aaaactacgc
     6061 ttcaaagctc gctcgaaaat caatgctagc ttttacaccg tttatatgtt ttccggtatt
     6121 ttgatcgttg ttccattatt taaaatcatt tccggtctag gtttgtatga taccaataca
     6181 gcactgatta tcacgatggt cgttcaaaca cttcctactg cgatattcat gctaaaaagt
     6241 tattttgaca cgattccgac tgatattgaa gaagcagcaa tgatcgatgg tcttagccgg
     6301 atccagatca ttattcggat cattatacca ttggctattt ctggaatcat ttctgtcttc
     6361 gtttattgct ttatggtttc gtggaatgat tatttatttg cttcgatttt cctgtcgacc
     6421 tccgaaaaat ttactttacc aatcggtttg aacacattat tcagtacacc agactacatt
     6481 tggggacgaa tgatggccgc ttcattggtg accgctttac cagtcatcat tatgtatgcg
     6541 ttatctgaac gatttattaa aggtgattta gtcgaaggcg gcgtaaaagg ataaaaagaa
     6601 aagaaagagg aaagaaaaga tgaaaaaatt agttgcatta gaaccaagaa tagccggatt
     6661 caaagattac gaagaccgtg agatcgaaaa gaacgaagta cgtatccgag taattttcgc
     6721 tactccaaaa ccaggaacag aaattgtcga ctttagagga ttaagtccat ttatcgatga
     6781 agaattttca gaagaatggc gcctattctt gccaagagaa gaaggaagcc aacgcggtgt
     6841 ggtatttggc gaatttcaat taggaaatat gattgtcggt acgatcgaag aaacgggcag
     6901 tttggtgaca gagtatcaaa aaggagagtt agtctgcact tatggaccca ttcgtgaaac
     6961 gctgattaca aacggtgttg ataattataa actacgtaaa cttgatcggt tggatcaatg
     7021 gaaaaatgca gtatgttacg atcctgctca attcgcttta ggtggtatcc gggaagcaca
     7081 tgttcgagca ggtgatgctg tagcaatctt cggtttaggc gctatcgggc aaattgcgat
     7141 tcaattagct aaaaaagcag gtgctactac catcgttggg atcgatccca tagcgcagcg
     7201 tagagaatta gcagaaaaat acggtgccga ttacacgcta gatcctatga aagcagatgt
     7261 cggttttcgt ctaaaggaat tgacagataa acgtggagta gattcagtta ttgaaacgag
     7321 tggcagtgct gccgcattac aagcttcttt aagagggatc ggctatggcg ggatcatttc
     7381 ttatgttgcc tttgctaaac cttttccagc tgggtttaat cttggtcgcg aagcacattt
     7441 caataatgca aaaatcgtct ttgctcgagc atctagtgaa ccaaacccag attacccaag
     7501 atggaaccgt aaacgaatcg aggacacatg ttgggaatta ttgatgaacg gttacttgga
     7561 ttgtgaagaa atcattgatc cagttgtgcc atttgcagaa agcgcagaag cttacatgcg
     7621 ttatgtagac cagcacccag aagaaagtat caaaatgggc gttcaagtcc gaggaggaga
     7681 acaatgaaat tcggtacgca agatcaagca tttttcccaa gagacatttt agaaaaattt
     7741 agatttatca aagactgtgg atttgaagaa tacgaaatcg acggtaagtt gttaatagaa
     7801 aatatcgaca cagtcaaaca ggcaatcaaa gaaacaggga tcccagtagt gacagcttgt
     7861 aacggctacg atgggtggat cggtgacttt atcgaagaac ggcgtcttaa tggtgtacgt
     7921 caaattgctg agattttgcg tgcactaagc gaggttggag gcaaaggaat cgttatccca
     7981 gcagcttggg gaatgttcac ttatcgatta ccgccgatgg tttcaccccg aagcaaagaa
     8041 ggagactata aagcagtcag cgaatcactt cgttatttag ataaagtagc cgaagaaaca
     8101 ggtacggtta tttatttgga gcctttgaac cgataccaag accatatgat caatttgtta
     8161 gcggatgcgc gtcattacat tgactctaat caattgaaac atgtgcagat catcgctgat
     8221 ttttatcata tgaatattga agaagatgat atttcaaaag cattgactac gcaaaaagag
     8281 tatgtgggtc atatccattt agcagataat catcgctacc aaccaggatc tggcgcaatt
     8341 gattttactc gccattttca aacgctactt caaaatgagt atgaaggtta tatggtatat
     8401 gaatgtcgtt tgcgaggaga aaatgaagtg aaaatttatc aggaatcatt gcaatacttg
     8461 aaaaactgtc tggaaacagc gcgtcattta aatgatttag agaaagaata gagaaagaat
     8521 aacaataagt aaataagcaa aggagagaga aataaatgaa gaaagtagca atcataggcg
     8581 ctggacaagt agcagaaaaa gtacatgctg cttattatca aaaaagatca gatgtcttag
     8641 aattggccgc tgtggttgat ccagtcagcc agcgagcaga agacttttgc cgacgtacag
     8701 gattttctca tgcgtataca tcagttacac aaatgctgaa tgagatttct cccgatatcg
     8761 tgagtgtctg tacagccaat cgctttcact tcgaacatgt attggctgcc ctcgaagcta
     8821 atgcttcagt gatgtgcgag aaaccaccag ctatgacagc tgatcaagca agaaagatgg
     8881 cagagacagc cgataaaaac gggcagattt tggcttatgg attccagcat cgtttttctg
     8941 acgaagcaac aatgatcaag aatcatcttg atgttctcgg ggatatttat tacgtagaag
     9001 cgaatgcgct tcgtcggtct ggtgttccag gctggggaac gtttatcgac aaagaacttc
     9061 aaggaggcgg gcctttgatc gattatggca ttcacatgct tgatacagcg atgtatatta
     9121 ctggatttcc taaagtaaaa agcgttcggg cgtacagctt ccaaaaaatt ggtacgaaaa
     9181 aaaattcagg gaaattcggg aaatgggatc caagcaaatt cacagtagaa gatgcaattt
     9241 ttggcacact ggaattagaa aacggcaaga tcatccaact gaatacttcg tttgctttga
     9301 atatcagaga agacaaactg aatgtggctt tttgtggcga tcaggcaggt gctaatctgt
     9361 atccaggcga actattcgaa gatgtagatg gaaagctggt ttccttacaa aagaccacgc
     9421 cagttaatga cccacatgaa ctaagtatgg ctcattttgt gaatcgggcg ctcggtgacc
     9481 agactcagat gattgcagat ggctggcaag gatatgtcat ccagaatctg gtggaaaatt
     9541 tatatcgttc ggcagaaaca ggagaagtta ttaccttatg aaagtagaag aaaaacagtt
     9601 tgatttagag tatatcaata agtatgcgag tcagatgacc attggaaatg gattttttgg
     9661 tatcagagga agccaggagg aagactatcg gaatcaagta aggggaatgt ttgcagctgg
     9721 tgtatataac cgacctttag gagcagaatc agccgagtta gtgaatctcc cagatgtcat
     9781 cagatgggaa ataaaaatcg acggtgaaca tttttctctt gagacgatga aagttcttgc
     9841 atacgagcgg gcactagatt tagaaatggg agagcttaaa cgctatgcgc tcattgaaac
     9901 tgctcaagga aaaaaagtgg aagtcattac ttgtcgtgtt gctgatcaaa ataatctcca
     9961 tcaggcagcc ctgaaagtgg tcatcaagcc gttgaccgaa gactgccaag tagatgtgaa
    10021 aacgggtatc gatggacagc aaaccaattt tggtacacag cagttggttg aaaaagaact
    10081 gcgagtattt ggtgacgatt tgatcagtgc atcctaccag acaacagaaa gtaaaattga
    10141 tattgggatt gcagctaaat tcaataaagc aggtgtattc caagcaaaaa atcgccggat
    10201 caccgcttcc ttttcagaaa agatcagaaa aaatacgtcc tttacgctgg agaagatcat
    10261 cgtgctctct acctctcttc agcaaacaga cccgtttaag aaaagtattg cccaagccca
    10321 gaaaagcgtt agttatacag aaattttaga gcagtcgatg tcttattgga cagatttttg
    10381 gcatcagcat cggataacga tccaaggcga ttcttctttc gatcagttag cgatggactt
    10441 cgctgcttac catttacaga ttatgactcc ccgcaatgat ccaagtgtta gtgtaggggc
    10501 gaagggacta actggcgaag gttataaagg gcatgttttc tgggatacgg aaatttttat
    10561 cctgcctttc tttttatatc agtttcctga agtagcaaag aatttgctgc tgtaccgtta
    10621 tgatcgatta gaaggcgcac ggcaaaaagc aagagattat cactatcaag gtgcactttt
    10681 cccatgggaa agcgcacaca ctggtcagga agagacaccc aaatttgctg cattgaatat
    10741 caaaaccgga acaagacaag aagttgcttc agctgccgca gaacatcata tcagtgcaga
    10801 ccttgcttat gccgttcaag agtatgtcca agcaacagag gatcaatcgt ttttagaaac
    10861 aaagggaaaa acgctcattc atgaaacagc agctttttgg ctgagcagag ctgtaaaagt
    10921 cgatgatcat ttagagatac acagagtcat tggtccagat gaatacacag aatatatcga
    10981 caataatgca tatacgaact atctggcgca ttataatgtg gccttagctg ttaaatatca
    11041 agctggcgat ccgctttttt tgaaagaatg tcaaaatttt ttagataagt tatatttgcc
    11101 agtgcctaac aaagaacagc tgattccgca agatgacacg tatctcagta agccagttat
    11161 tgatttgacc acttacaaag aacgtcctgg cagccagtct attttacttg attatgcccg
    11221 tagcgaagta aatgaactcc aagtcagcaa gcaagcagat cttgtcatgc tgttatactt
    11281 attacctgag tatttttctc aaccaatcgt ttctaagaat ttgcattact atgaaaacaa
    11341 aacaatccac gactcatcgt tgagtaaagc gattcacgcc atagaggctt gccgtatcca
    11401 agaaatggaa tgggcgtatc atttattcca agaagcgtgc ctgattgatt taggaccaga
    11461 tccgcattca tcagatgacg gaattcatgc tgcttcatta ggagcactat ggctagcagt
    11521 tatatttggt ttttcaggta ttacagtaac gaatggaact ctttctattt ctccaagact
    11581 tccttcagca tgggaaaaaa tttcttttcc ttttatttgg aaaaatcaca ggttgctatt
    11641 tgttttgaca aaaaaacaaa tagtaataaa aaaagagacg aaagaaacat tacctatttt
    11701 tgtcaatgga gaccaatacc agctggaaaa agaactgatc ttggaacgga ggggaaaata
    11761 atgcgtattc tgattgcgcc agattctttc aaagaaagtc tgacagcctt agaggcagca
    11821 caagccattc aatcaggttt tcaagaagtt tttgttcagg ctgaatatga tctgctacct
    11881 ataggcgatg gaggagaagg aacggtttca tcattagcag acagtttaag gttgaagcgg
    11941 caaacagcag tcgttactaa tgcatttggc aaaaacaaag aaatccagta cgcttcagac
    12001 ggtcaaactg cgatttttga aatggcagaa atcgtcggat tgaaagatgt cccactaaac
    12061 caacaacagc cacttaggtt atccacgcga ggagtaggag aactgatacg acaattgttg
    12121 caacaaggtg ttcgacacat catcatcggc gttggcggaa gtagtaccaa cgatggcggc
    12181 atcggcatgg cagaaggtct aggttatgct ttttacgatc aagataatca aaaagtagaa
    12241 gcactgggag aaaatctagg taaaattgct acagttgata aaacgaacgt gcctattgag
    12301 ctgattaaag ccaaaatcac tgtcattact gatgttacta atcttttatg cggaaaagaa
    12361 ggcgcttctt ttgttttcgg accacaaaaa ggcttgaaag aaaatgaatt agcagtggct
    12421 gaccaagcca tgcatgattt ttatatgaga tttgcccctc aagtaatcga ggcatcgggc
    12481 agtagtgctg gtggtggaat gggtgcagga ctgttagcat ttgcttcagg gaaaatagtc
    12541 tctggcatcg actacgtatt ggatttactg gagttcgata cgggtacagc aagcagacct
    12601 cgtaatcgta ggcgaaggac gtctagatgg acaaagtcta aaaggaaaag cgccagttgg
    12661 gattgctaga agagtaccag agggcgttcc tgtgatagct atttgcggaa gtgttggtaa
    12721 aggaagcgaa aaagcagcag atgttggcat ttcggccgtt tttccgatcc ttcctgcagc
    12781 tgtgccttta caagaagctt tacagcaagc cactgataat cttcatcgca cagctaaaaa
    12841 catcgcatct ttacttcaag tcgttcattt tcaaggaggt aatcgatgaa aatcaaagca
    12901 gcactattcg atttagatgg cgttcttgta gacacagctc gttatcatta cgaagcgtgg
    12961 ctggttttag ctaaccagct gtccattcca ttcactgaga aagaaaacga gcaactgaaa
    13021 ggaatatcca gaaccgagtc actagagcga ttgctgtcat ttggaaaaat ggaacagaaa
    13081 ttctcagaaa aagagaaatc agcctttgct gagcaaaaaa acaatctata tcttcaagcg
    13141 attcaaaaaa tggatgaaac atccgttttg cctggtgcaa tagctgttct tgagtacttg
    13201 aaaaaaacaa acatcaagat cggattggga tcagcaagca aaaatgcacg cctcatttta
    13261 gaaaaaacga atttgacaag ttattttgat gtccttattg acggcacgca agtatcaaaa
    13321 gcaaaacctg atccagaagt ttttctcaaa ggagcacagc aattgaatgt accgccaaat
    13381 gcatgcttgg tcattgaaga ttcagaagct ggttgtcaag cagctttggc tggtaacatg
    13441 catgtattgg gaataggtga aaacataaat cttccttctg ctgaatatgt gattcctgat
    13501 ttaaccgttt ttgatcaagt acgttcgttt tggcatttat cagaagccgt atcacgtata
    13561 taatagtttc cgttttttct gtcacaagca aaacgttatc ctccttttgg aaatcaaggt
    13621 atgatgagaa aaaaggggga ttttatatga caaaaaaagc agttttcgca ggcggatgct
    13681 tttggtgtat ggtcaaacca tttgaagagc agccagggat catttctgtg acatccggtt
    13741 atactggcgg gcatgtacca aatccaactt atgaacaagt aacaacaggc acaacagggc
    13801 atacagaagc agtagagatc gaatatgatc cagaagttat ttcttatgat cagttggtgg
    13861 aaatctattg gcagcaaacc gatccgactg acgcattagg acagttcgct gatcgcggtg
    13921 attcttatcg tccagtgatc tactataatg atgaagaaga acgaaatatt gcagagcgtt
    13981 caaaacaagc attgcaagac agcgggcgat tcgataagcc aatcgtgaca aaaatcgaac
    14041 caagaagcga attttatcct gcagaagatt accatcagga ttattacaag aaaaacaagc
    14101 tccattacaa tctttatcga gaaggttctg gacgtgcagg tttccttcgt cgacattggg
    14161 gcgtcaagaa ataagaagcc gaaaaagcta cttatggaac accgtatatc agaggttgta
    14221 aaaccagcat tttgagctaa tactgagggt cagctgattg aacaccattt agtggagagg
    14281 ttgtgaacct gtcgcctagc tccaagtcac aaggatttgg taagagaaca ctatatatca
    14341 gaggttgtga caagtcgttt gtcacaacct tttttcaata cctaagatga aggacaatca
    14401 gcaacgcact gctcaaaaaa ggaatgaaag gcagcttttc caactttttt ttatgacaga
    14461 taaagtaaac agaaaaaacg gatattccaa acagactagc aagaaacaag atctgaagca
    14521 actcttctag agacaagcca ccactccaag aaagcatcaa cagagtatcg ccagctccga
    14581 gataggattg accatagcga aggcacacac cgcctacgat aaacgttaac agcacacttt
    14641 gccattggaa gacgccggcc tgcaaccaaa aaatccataa aattgcccaa gaacagaata
    14701 gcgtgtgaga atggaccatg aagtaaaata aatccatcaa cgaaaatagc aaagccgaaa
    14761 gcatccatat gaacgtcgaa aaatttcttg cggaagaaaa agtaaagaac caggcaaaaa
    14821 gaccaccaca taaggcttct gccaacaaat agtagaaggg caaccgacac ctgcaatagc
    14881 ggcagcgaaa tcgttggacg atgatcgaga gaatcggaat caattcatac caagaaagcg
    14941 aacgacagca tttgacacaa tgagatctag gataaataat agagtgacct aacggaatcc
    15001 gctgggcggt taaacataaa aatgatccga tacagcaacc aatgataaaa taaagtaaca
    15061 cgccatctcc cccttttcaa aaccaagata cgcaagctta aactaaattt ttgtacatac
    15121 ataaaatttg aggtgaaaaa atgaacgttt caatcggatt agatatcgga accacacaaa
    15181 ccaaagcagt tgctttcaca gatgaagccc aagaagcagc atccgcttat tttcgctacc
    15241 ctttgatcca agaaacacaa gggatggcag aacaagatca ggaattgatc tttcaaggtg
    15301 tctgcaccgt tataaaagaa gtaattaaac agttgccttc agacacaatc attcaatttg
    15361 tctccttctc ctctgcgatg catggcctga tattgttgga tgaagagaaa acaccgttat
    15421 ctcgaatgat cacttgggca gataaccgag cagcggacga agcagaaaaa ctgaaatata
    15481 ccgtgcttgg caaagaattt tatcggcaga ctgggacgcc gattcatcca atgacaccat
    15541 tgaacaaaat caagtggctg caaaacagcc aacctgaatt attcaaaaaa actgcttatt
    15601 ttgtcggtat caaagactat atcttttata gattgtttgg cgaactgatc agcgactacg
    15661 gaacagcttc aggaactgga tattttgata tccatgaatt ccaatgggca gaagaagtgc
    15721 ttgactactt gaacattcga atagagcaat tgccgcaagt ctttccttcc acctatcaag
    15781 taacaggtct accatcaaaa acagcagcag aactaggttt gccaaatgat atatcatttg
    15841 ttttgggagg ggcagacggg ccgctttcta atctagggtt aggtgctttt ggtgatacga
    15901 tcgccgcttt gaccgtagga acgagcggag cacttcgttt tattactact cagcctcagt
    15961 tccatccaga aatggagacg ttttgttatg ttctggatca gaaacattgg gtagtgggag
    16021 gagcgactag caatggtgct ggcatctttg attgggcagg gcatacattt ttacaggaag
    16081 tcgttcaatc tgctaaagaa aaaggagaaa atccatatga tgcactgctt tcggctatcg
    16141 cttttgtgcc agcgggtgcc aatggtctga tttttcatcc ctatttactt ggtgagcgag
    16201 caccgctttg ggacgcagat gcgtttggca gttttatcgg tttacagcgg caacatacag
    16261 aaaaagaaat gatgaaggcg attctagaag ggatctgtct caacctttat cggattttaa
    16321 aaggagtttg ccaggaaaat cagctcacag agatccgtgc tacaggcggg tttgctcaat
    16381 ctccgatttt tcgtcagatg atggctgatg tactgggtta cccgcttgtt ttccctactg
    16441 tcacagaagc atccgcatta ggagctgtga ttttaggctg gagaagcatc ggaaagatcc
    16501 aaagtatcag tgaagcacag gaattgatag aattgaaaga gcaagttgga gtacaagaaa
    16561 ctgatcataa aaaatatcag aaaatctatc cattatttgt ttcgacacaa aagcatttag
    16621 cacagactta tcagcaattt gctcaactgc gagaagaatt agctgattct gaaaaatgat
    16681 tggctttacg gataaaaaag cgaactgaaa atcgttctca ggtaaatgat tttgttgtac
    16741 ttttcattga aagtctacta ttattttaag tgtaagaaaa tgttaggagg caagaaagat
    16801 gaaattccaa caaaccaaag aagtattaaa tcaattagtt gcagatctaa gccaaatgtc
    16861 tgttgttgtt caccaaacac attggtacat gagaggacca ggtttcctta cattgcaccc
    16921 aatgatggat gagttcatgg atgatttgaa cgctcagtta gatgaagtat ccgaacgctt
    16981 gatcacatta gacggttcac cttattctac attgcgtgaa tttgcagata acacaaaaat
    17041 ccctgatgaa attggccgct gggatcgtac tattccagaa cgtttggaaa cacttgttgc
    17101 aggctatcgt tatctagcag atctttacca aaaaggaatc gaagtttctg gagaagaagg
    17161 cgacgatcca acacaagata tctttatcga attcaaaaca gccacagaaa aacgtatctg
    17221 gatgatccaa gctcatttgg gcaaagcgcc agagatcgac gcgtaaaaac tgttgttgaa
    17281 cttgaccgaa aaagaggttg tgaaatcagc gttttgacct gagtattaga gaaacaaacg
    17341 tcaaaatagt tcctcatatt ttgccgtttt ttgagct
//
LOCUS       DADGHT010000059        16906 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.059, whole genome shotgun sequence.
ACCESSION   DADGHT010000059 DADGHT010000000
VERSION     DADGHT010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.059"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(229..2121)
                     /locus_tag="JX887_001805"
     CDS             complement(229..2121)
                     /locus_tag="JX887_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1257787.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2118..3845)
                     /locus_tag="JX887_001806"
     CDS             complement(2118..3845)
                     /locus_tag="JX887_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1257788.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3861..4511)
                     /locus_tag="JX887_001807"
     CDS             complement(3861..4511)
                     /locus_tag="JX887_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1257789.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4715..5011
                     /locus_tag="JX887_001808"
     CDS             4715..5011
                     /locus_tag="JX887_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAX1257790.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5183..5803
                     /locus_tag="JX887_001809"
     CDS             5183..5803
                     /locus_tag="JX887_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAX1257791.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5895..7061)
                     /locus_tag="JX887_001810"
     CDS             complement(5895..7061)
                     /locus_tag="JX887_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAX1257792.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7073..7426)
                     /locus_tag="JX887_001811"
     CDS             complement(7073..7426)
                     /locus_tag="JX887_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAX1257793.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7554..8576
                     /locus_tag="JX887_001812"
     CDS             7554..8576
                     /locus_tag="JX887_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAX1257794.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(9015..9449)
                     /locus_tag="JX887_001813"
     CDS             complement(9015..9449)
                     /locus_tag="JX887_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257795.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9559..11418)
                     /locus_tag="JX887_001814"
     CDS             complement(9559..11418)
                     /locus_tag="JX887_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAX1257796.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11536..12696)
                     /locus_tag="JX887_001815"
     CDS             complement(11536..12696)
                     /locus_tag="JX887_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAX1257797.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(13003..13914)
                     /locus_tag="JX887_001816"
                     /pseudo
     CDS             complement(13003..13914)
                     /locus_tag="JX887_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
     gene            complement(14080..15273)
                     /locus_tag="JX887_001817"
     CDS             complement(14080..15273)
                     /locus_tag="JX887_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1257798.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(15357..15560)
                     /locus_tag="JX887_001818"
     CDS             complement(15357..15560)
                     /locus_tag="JX887_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAX1257799.1"
                     /translation="MMNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVI
                     MNGNRIQIKRKQFEKIIDTLDTI"
     gene            15817..16059
                     /locus_tag="JX887_001819"
     CDS             15817..16059
                     /locus_tag="JX887_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257800.1"
                     /translation="MAHQPSGSAQTECVRMPYDAPPLSCGHIYQGAIRPPGKHRNGER
                     VSRFMLPGPVRQFVTIAWMSLISRRRFMASSRHTCG"
     gene            complement(15981..16214)
                     /locus_tag="JX887_001820"
     CDS             complement(15981..16214)
                     /locus_tag="JX887_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1257801.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            complement(16221..16652)
                     /locus_tag="JX887_001821"
     CDS             complement(16221..16652)
                     /locus_tag="JX887_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1257802.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
BASE COUNT         4751 a         3695 c         3172 g         5288 t
ORIGIN      
        1 cttattaccg cagatgcaag cttttgaaca ccgtttaagg aagaggttgt aaaatcagcg
       61 gtttgacctg agtattagag atacaaaacg gaaaaatagc ttctcatatt ttgccgtttt
      121 ttgagctaat accgaaggac agctgattga acaccgttta ttcggaaaaa gggactgtga
      181 cacgactttt gtcacagccc ctaaaaaaaa taataaattt gtactattct atgaagcttc
      241 ttcttcagaa aactgactgt tataaagatc tgcatagaat ccgtcttttt ccatcaatgt
      301 atcgtggttt cctgtttcta cgatcgaacc atgattcatc acaataatgt tgtctgcatc
      361 gcgtattgta gacaagcggt gagcaacaac gaaacttgtc cggttttcca ataggcggtt
      421 catcgctttt tgaatcagta tttctgttcg tgtatctaca ctagatgttg cttcatcaag
      481 gatcaggaca tctggatttg ctaagaatgc ccgcgcaatt gtgattagct gacgctgccc
      541 ttgcgaaata ttgcttgcat cctcgtttaa tacagtgtta tatccttctg gcaatttacg
      601 aacaaaatcg tctacgtgag cagctttagc agcctcaatg atttgttcgt ctgttgcatc
      661 gtcgttccca tatttgatat tgtcatagat acttcctgta aacagccaag tatcttgcag
      721 taccattgaa aactgtgcgc gcaattcatc acgtgaaaga tcacgggtat ctacaccatc
      781 gtaacgaata ctacctccag aaacatcgta gaaccgttca agaaggttga tcagtgtcgt
      841 cttccctgca ccagtcggac ctacaatagc gaccatctca ccaggtttga catccaagtt
      901 aaaatcagtc attagcaagt tatctggtgt gtagccgaat tgaacatttt caaaacgaac
      961 tttgtatggt gtatcttttt cttctggaag gccagatttt tcattggaca tctcttcttc
     1021 atccaacact tcaaataccc gttcggctga agcaactgtt gattggatag tgttcatcaa
     1081 acttgcaagt tgagtgattg gttgagagaa ctgtgttgta tattgcaaga acgcttgaac
     1141 atcccctaat gtcatgttcc catttgcaac ttttactccg cctagtacag cgacgaacac
     1201 atagcctaga tttttaacga aattcatcaa cggcatgatg attgccgaaa taaattgagc
     1261 tttccaacca gcggcataca gattctgatt ttctttttca aatacttcct ggtctttttc
     1321 agtatgattg aatgttttaa caatggtatg accaccatat gtttcttcta cttggttatt
     1381 caataaacct aaactttttt gctgatctgc gaaaaacact tgtgatttcg gcgctacgat
     1441 catcacgatg atcaagctta aagggatcat caataacgcg actaacgtca attgccagct
     1501 gattgaaagc atcatcacga tgaccccaat caatgtgact gcactagtta caaattgagt
     1561 caaattttgc tgcagcgtgc ttgcgatgtt atccatatca ttgattgctc gagacatgat
     1621 atccccattt gtatgtgtat cataatagga aatcggtaca cgattcattt tggcttccaa
     1681 atcatgacgt aattcataaa ctgttcgttg ggaaacacgt gtcataataa attgctgtaa
     1741 aaagttgaat acagcagaaa tcaaatacat cacgattact gtcgcaatga tctgcgcgat
     1801 tttatcaaag tctatcggaa attttgttac ttgttggcct tgttgcatct gttgagcgcc
     1861 agccattaca cctttgaata tttctgtggt tgctttcccc aagacctttg gtgtttggat
     1921 ttggaagatc acggctgcta ttgctagtac aaatacagcg atgatcgcaa ccatacgttt
     1981 agacatatag ccaaacaatc ggcgtaccgt tccccagaaa tttttaggct tttcaccttt
     2041 tacaccgaga tttctgccag gtccaccatg tcctggaccg cctgctggtc catgagaggg
     2101 acgtgtgttt gttttactca tgctaagtcc tcctctctta gttgtgaatg aacgatttct
     2161 tgataagttt cgtttgttgc taatagttct tcatgtgttc ctttgccaac cagttttcct
     2221 tcatctagca caaggatcat atctgcatcc attactgtac ttactcgttg agcaactaaa
     2281 acggtgatac tttctttcat attcgttttc aatgcttggc gaagattggc atccgttttg
     2341 aaatccaacg ctgagaagga atcatcaaac acatagatat ctgctgtttt gactaatgcc
     2401 cgtgcaattg ccagacgctg tctttgtcca ccagagaagt ttcctcctcc ttgttccaca
     2461 tggctatcta agccatcttc catctctgaa acaaaatctt tagcttgtgc gatttctaat
     2521 gctttccaaa tcatttcatc tgttgcatcc ggcttaccat actgcatatt gtctcggatc
     2581 gttccagaga acagaactgc tttttgagga acaaagccca ttaattctcg caaattatat
     2641 tgagtcatgt cactaatgtc cgttccattt atttggatcg aaccagattc gatgtcatat
     2701 aatcgaggga tcaaattgac taaggtcgtt ttacctgaac cagtcccccc tatgattgcg
     2761 acgatctcgc ccgacttggc ttggaaatca atatcttcca atgcaagttt ttctgctcca
     2821 tgatatcgat aattgacatg attgaaggcc aatgttgcgt tttttccagc aaaagaaact
     2881 gttttaggat tttcagggtc atggataccg attttttcat ccaacacttc attaatacgg
     2941 tcagctgaag cttgtgcacg aggcaccatg ataaaaatag cggaaagcat cataaagctg
     3001 atcaagatct gcatcgcata agtcataaat gcaatcagat taccgacttc caaagtcata
     3061 tctgctatgt agtgtccacc aaaccaagtg attgctacgt ttgtaccgct catgatcaat
     3121 gtcatcattg gcatcatcaa tgcgacgatc gtattaactt tgattgccgt atttgtataa
     3181 tctttattcg ctaaatcaaa acgattttct tcaaagcgtg tcttatcgaa tgctcgaatc
     3241 actctgaccc ctgtcaatcc ttctcgaaat accaggttta aacggtcagt tttcttttgc
     3301 atacttttga ataatggaac agcaaagtac atgattccgc cgatcaaaat aatcattact
     3361 gggatgacaa ctaagaagat ttttgtcaac tgatgatctt tttgataagc aagtatgctc
     3421 gcgccaatca acgtgattgg tgcattgatc atcatacgta aaaacatttg tgtaaccatt
     3481 tggatttgag tcacatcatt ggtcgttctt gtgatcaaag aggccgttcc atatttatca
     3541 aacgcatctt ttgtcagact ctctgatttt ttatagacat ccgtacgcaa ttgcttaccc
     3601 agtttctgtg attcacgagt agcaaaaaat gtatttgcga tagcagctaa gatactgatc
     3661 aaagaaaagc cgatcatcac aaaacctgta tgccaaatat aatcgacatc tccttgcgct
     3721 acccctttat caataatatt ggaggtaagt gtcggcaaat ataaatctgc cagtacttgg
     3781 atcaccatga aaactgcagc tgcaattgct gaagtcaagg agatccgttt tacgattttt
     3841 agcatctagt tcccttcttt ctatttatat actccgtttt tcagccaaga aagtttcaaa
     3901 ttgaattcac tgattgcttg ctctactgag taatcttcag atgttgaaaa taagcgatac
     3961 gaatgcgcaa ttgttgtaaa tacagtattc atcactaatt ggatcagtaa ttccaattca
     4021 tgatcatttt ttactttcag cttcgtccga tcgatcaatt caagcaactc ttttgcatct
     4081 tgtttgtgtt ctttatgtgg atcgtgaggc gttttttggc gactcgtatg aggagcgact
     4141 tttcttgagg cacggtaatc catgttcata aacaagttac gataaaaaga agcattctcg
     4201 ccttccaaaa tctcataaat cattttagaa aaataggatt cgaatccttt gaatagatca
     4261 ccatcggatt ctttcattag ttgtaacata tctttagagc tgtcacgtct cattgtctca
     4321 aagtaataaa aataaagatc ctctttatct tcaaaatact gatagaaact gcctctaggg
     4381 atatccgcta atttgacgat attagcaatc gaagcttctt ttaagggtac tctagaaaac
     4441 tcgattctcg cagcctcgat tagtcttttt tgtttttctt taggcaaatg gaaaaatgtc
     4501 tgtgtcggca tatggatcct cctttctttc aagatgacac attgtcatat gacgctgtgt
     4561 cattataaca cctcctacct gttttgcaag acatttgcat agtttttttc attatcatcc
     4621 gatacattaa aaaagtgata agaggaatcc ttccatttga attaatgaga gttgcccatt
     4681 aaaatagcca catactaaac aaaggatgag ataaatggcc caatcaatta gtgtccaaga
     4741 cttcaataaa ttgcctctcg atgctgacag catcgtttta gatacaagaa ataccttaga
     4801 ttacacaaaa aaccacttaa gccactcgct ttctatcccc gctgctatct tgccaagaca
     4861 attaaaaaat ctagatccaa agaaacttta ttatattcta agctatacag gcaggcgatc
     4921 agaagcatta gccgatcaac ttactgctaa tggttttcgt gctgtttata tcattggtgg
     4981 gatggaagct cttcagtcga gtgttgcttg aatattgctt gttagattca aaagaggctg
     5041 tgacaaaaaa tcgtgtcaca gcctctttta taccctgtct ttttttagtt atttattctt
     5101 caaccttatc aatatgactt gatagccttt tctttttctc atagttataa caatcatagc
     5161 aataaaagga gaaggtaagc atatggcatc tgttttagta gtcaaaggtc atcccctaac
     5221 tgcagaagaa tcgcgcacag ttaaggcatt gacgtctttt ttaacaagtt ataaagaaaa
     5281 tcatccagat gatgaagtga ctgttttgga actttatcgc gatgatattc cggaaatcga
     5341 tgaagaatta ttatcaggtt gggaagcatt acgtgctggt gcagaattca cttccttatc
     5401 agaaagtcaa caacaaaaaa ttgctcgttt caatgaattg actgatcagt tccttgctgc
     5461 tgataaaatc gttatcgcaa acgccttatg gaatctaaat atcccaacaa aattaaaagc
     5521 ttggttcgat accgtcaatg tagctggaaa aacgttccgc tatacagaaa acgggccaga
     5581 aggattagtg acaggtaaaa aagcactgca catccaatct aatggcggtg tatacaacgg
     5641 acaagacttt gcctctcaat atgtaaaagg tattttaaac tttgtaggca tcgatcaagt
     5701 agatcagcta ttcatcgaag gaatcgatta tgaccctgac cgtgcagatg agttgatgca
     5761 aaatgcatta gataaagctg ctgctttagg taaatcattt taaaaattga gataaatgca
     5821 tacaaaagag acagaggaaa aaatcttcaa agcagcattt gtaccttgga tattttccca
     5881 tctgtctctt tttgttattc tttctgcttt ttcaacggat tttcttcata aagagaagag
     5941 attgttgtgt accattcaaa aacatgagta atcactactt tagctgctgc ataaacagga
     6001 atccccaaga tcacaccgat gattccgaac aatttcccag aagtcagcag aactaataaa
     6061 atcgttactg gatggattgc taactgattc cctagtacta atggagagat caagcgtcct
     6121 tctattgtct gctctactgc aaaaacgatc agtactttga tgatcatgaa tggacctgct
     6181 acaatggcta aaaagatagc cggaatcatc gctaaaaatg atcctaagta agggatcagg
     6241 ttcaaaaaac ccgcaataat ccccaacgtg acagcatact ctaaaccaat gaccgcaaaa
     6301 ccaatcataa acatgattgc cacagcaaaa gccacagtta gttgtcctct tatataagaa
     6361 gaaacttgac tattcatttc actcagcaca ttcaacgtcg gtttttgcat gcgtgtcggt
     6421 aaaaatttga caaaataagg tgctaattgt ttaccgtctt tcaatagata aaataagata
     6481 aacggcatcg tcagcagagc cactaaaata gtcgctaccg cgccgacaaa acttccaaga
     6541 ctctgaactg tactcttaga tatatcttgg atcatatcgc ctgccgaatt catgaactta
     6601 tcacctgctg tttccaactg ttcgcgaaat tggttgaaca gcgggtcccg caaaatctcg
     6661 gttaatttat tatcaatcgt atctacatat tgagggaagt tactgatgaa gctcactgtt
     6721 tgttcctgaa tcttagggat gatcactacg ctcccccatg cgattagtgc aacaaccaaa
     6781 acaaacagcc caatgatact gtaaagcctt ggtacttttc gcttttcaaa gtaatcaact
     6841 accggattca tcaagtaata caagattcct gctaaaatga taggcagacc tacgattgct
     6901 aaaaattgcc agattggtgc aaacaaatat gaaacttttg taaataaaaa gacgatcagc
     6961 aatattaaca atacaacaag taaggctgtg actacttgat tatttaaaaa ccagcgccaa
     7021 aaccacgata ccggtctgtt cttcttattt tttccttcca taattcctcc tgttagttat
     7081 aaaaaatttg gcttcccaaa ccaatagcag gcagtctatg cggatgaaga tagattccat
     7141 ttgcaatttg tccttcttct ggacaagcat caaaaatcaa tgatacgtga gctactgtct
     7201 ctaaattccc attggccatc ggaccgacat aatcgatcgt atatacctga tcatcaaaag
     7261 caattgttcc gcctgctttc aaagaaaaag gttcgtcttt tgatacttct tgaatcaccg
     7321 aatattttcg taaggcagct gttgctgttt tatcgaacaa aatcagcatg ggttcttcct
     7381 tgtttattgc ttctgtccca atttctgtaa tctttgcctg aatcattgca ctctctcctt
     7441 taattgcttt caaaaacagt ataacacatt ctcattcttt agccgtgtgg aataattatg
     7501 tgatagaata aaaacgaaaa ctatttcatt acaattagga ggaatcagct catatgatcg
     7561 aaaagataat tttaggaacc tatacgcgtc gcgaaagtaa aggaatctat acgatcgacc
     7621 ttgatacaga aaaagaagaa ttagccaacc tttcattagc tgttgaagaa aatagcccta
     7681 cctatgtagc aaaaagtaaa gctggcaatc tttacacagt tactagtgtg gatggattag
     7741 gtggtgccgg tgcgtacgat aaggattttc attttttgaa tgcggtaaca gagtctggcg
     7801 ctcctttgtg ttatgtagcg gttgatgaag cacgtcaatt actatacggg gcgaactatc
     7861 ataaaggtga agtaaatgtc taccatatat taggagatgg cgaactgaaa gcagcagatt
     7921 caatattcca tcaagaagcg acaggtcctc ataaaaacca agatcatgcg catgtccact
     7981 atacggatct gactcctgac caacgattag tcgtatgtga tcttggtaca gatcgtgtgt
     8041 atacttatga tgtgtccgaa aacggcaaat tgaatcttgt aactaccttc actgcagagc
     8101 caggaacagg ccctcgccat cttgtctttc atccaaatgg acaattcgct tatttatttg
     8161 gtgaattaga cagcacagtc cgcgtgcttt cttataataa agaaacaggt gcttttgaag
     8221 aattacagaa aatatcgacc ttgccagaag aattcgacgg tgaaaatgga ggggcagcta
     8281 tccgcatttc aaatgatggc aagttccttt atgcttctaa ccgaggacat aactcgattg
     8341 ctgtattcgc agtttttgaa gatggttccc acattcaaaa caagcaaatc atctcaacag
     8401 aaggggattt tccccgcgat ttcgcactag atccaagcaa taattttgtc gtgtgtgcca
     8461 atcagaacac cgataatctg acattatatc gccgtcatcc tgaaacagga ttactggaat
     8521 tactgaaaaa agatgtctat gtaccagaat gtgtctgtgt ttattttgat cgttagtaag
     8581 aaaaggagaa tgaaatgaat cagcaagacg tattagacag actacgggaa gaactaaata
     8641 ttcctttctt tgatgggaaa atcgaagata aagagtatag cgaagaggaa tatcagaaac
     8701 tcaaagccga tttacagaac tactttgaac aatatgtaca gaatgtagaa aactaatcag
     8761 ctttccatac tatctgaaaa gaacatcagg acaagacttt tccgtctatc ctgatgttct
     8821 tttctacaaa taaaaaaccg ccgagatggt tagactcgac ggaaaaggag tatttactcg
     8881 attttgagta agtacaaggt tgttgttggt tataggtatg tcattatcat aaaggatttt
     8941 gatcactcta tcataaaggt aatattacat ttatattaga taactctagt ttttattgtt
     9001 atcaaagatt tcttttattt tttcaacaac aaattagtca ttttttggat ggcagctgtc
     9061 aattggtctg tcgcttggtc ttgttttgct tcagatgtat tgaatagatc ttcatctacc
     9121 cctgattcaa gatcgatact ttggatcatt tcttcacagc ctgctacata tgaaagataa
     9181 gctttttcaa aatttttatg aatgcccatt gcttttgctg gtggacgcaa agtactgact
     9241 ttcttaagca ttgcccgata tttttttgtt ccttcttcaa ataacaggat gatctcttca
     9301 agagtcgatt tgtccagttc acttgttttt ccttcatcaa ttgcgtttct gatcacttca
     9361 tatttcggat gcattccttc tccgattgct tctgtttcct tgacgatttg atcgatggac
     9421 tgcacataat agccaatatt cggtaacatg ttcgttttcc tactttctcc attgttgtta
     9481 ttatttattc tacttgtttt tatcctcaaa tgacaagtac ttgaaaaaat ttaatggttt
     9541 ctatacagct cgccattctt attcgtgctc aaagaaacca tctgctaaac tatattgttt
     9601 ccctgcgaca atgtcatatt ggatcaattg atattcgtcg taaatctctt gttgcgagcg
     9661 attgaattgc gcttctttat accactgtcc gttttgatag tacagttctc gttcaaacgc
     9721 cggaagttcc tgttctaatg ataaaagcag ctgataaaag ccatttgttg tctgattcgt
     9781 ctgttccatt agattcgctg caaaataaaa cggactggtg attgcatcgt gagtcgtttg
     9841 cttttctaat tctcctttac tgtcgaacat aagaaattgt gtttcatgca atgtttgttt
     9901 gtcatttttt gcttggatcg tatctgaata gatccctgga agatgatccc cccaaaaaac
     9961 aactaaagtc cttctagaaa gattcttcaa ttcttccgtg aactgcttca gtgccgtgct
    10021 gctataggaa atatcttgca gataattctc taagtcaagt gtcccacttc catctgaagt
    10081 ttttgcagga tagtctagat tatcatactt tccatcgtag ggcatatgtg tctgcatcgt
    10141 gactaaatga atgaactgag gtgttttttc ttccttgaga agtgtcatta cttctttgta
    10201 agctgactca tcagaaatat atggattatt ctctatcgta tccgtatagg tcatcgtacg
    10261 ctcgctgatg aactggtcaa atcctaatgt ctgataaaca tcctctcttt tatacatcga
    10321 agtattgtat ggatggatcg ctgtcgtctg gtatgattgt gcgtttaacg ctgaaacgat
    10381 agaaggaagc tgatccattt ttggtacaag catcgtgtaa ggggtggtga gttgcgcatt
    10441 aaataacgcc atagaaaaac cagtcaatgc ttcaaattcg atatttgctg ttccaccgcc
    10501 atagttttga gaaagcatat tgccactata tgtttgatca gctacttcat aataatctgc
    10561 caatggctca ccagatactt ctacgccgtt taatcgacta ggatctgaga aactttcact
    10621 catcacgaac acgatgttcg gcgactcttc ctctacagtt ttattttttt catcggctag
    10681 cttctggtat ttttcagtga tttctttgat cttttctttc gaatatcctt caggttcatc
    10741 cattggttct accttcagat tgtacaaaaa cccaccgata aaaccagtgt tatagtagtt
    10801 cattttctgg ctgtaaggta tccatagtgc cgttttatta tatgcttttc gcaacaaatt
    10861 atcgggattg ttgaaattac tgatataccc tagcagtcca attgccacaa gcagtgtcgt
    10921 taatcggatc aattggaatc gccttccttt tttcaggctt cgaaacatgt accagcaaaa
    10981 caatcctatc acggttcctg cggcagctaa gatcactgta aacagcatag tgccggtcat
    11041 atctttcagc aatccgattt cagtgatcat cttcaaatcg tctggataaa tcggttcttg
    11101 ccgataactc attttcatat aatttgcaaa acctaataca ccgatggcta cgacatacgt
    11161 aagggaacct aaagggacag atcctgctag tgcaatcaga aaaataagaa taatcagcaa
    11221 gacgagacag gctaagaaga atttttccgt atgccaagaa aaagcaaatt tcaacgcaag
    11281 gtctacggat agatcatttt gacaccactg caaaaataaa ttactaaaaa caacaagaaa
    11341 aaagatactg atgattgctg ctgttccttt taaaatcttt ttctgtttgg tcgaaagtct
    11401 gcttatatat cttttcaaat gcttgctcct tcatttctat caataaaaga atgttgcttc
    11461 tcttatttta gttgtacgaa attcgaaagt aaagaacgga aagaagaatt aatgaaatcc
    11521 aaatattctc tttctttatg gcctttctgg tttctttaat aagcggacct ttcgtactcc
    11581 agaaattttt tctagctgtt gtttcacttg attgagctgt tcaaaatcag tactgtctat
    11641 gtcaatcaat atgtagacat gctcattctt atggttacgc gatatatctg cgatcgctag
    11701 ctcgttctca ttcagcagag aaaatatctc tgctaatata ttggttttct tttgataaaa
    11761 tatagtgaat cgaaacggcg cttggaaaaa cattcgtgcg gatggataat tgaccgcttc
    11821 tctaaccgta ccgaacaaaa gataatcttt taaggcttca actgccaaac gtccgctgtc
    11881 tgccaaagct tcctgagtcg atccccctag atgaggcaac ataagtatac ggtcattttc
    11941 taagaactct tcttctggaa aatcagtcaa gtatttagcc agatgttgtt tttccaatgc
    12001 ttgcataaca gcatatttat caacaatttc acttcttcct acattgataa gtacagcatc
    12061 ttttttcatt ttttctatat tcgcctgatc gatcaatcct tttgtatctt ctgtcaacgg
    12121 cagcatgact acgatgtaat ccgaggtaga aagaactgtt tctaaatctg cttgccgaac
    12181 ataatccaac tgggcatcgc ggatagaata acccaagaca tccatcccta agctatagca
    12241 acttagcgct acttttgtgc ctatcgctcc aagaccaaga agaccgatgg ttttgccttg
    12301 caattctcgt cccacataag cacttctttt gttttctgcc tgttctaaaa tattaggacc
    12361 tgttagtgtt tgtaccatac gacttgcttc gattatcgga cgggaagata agagcaaaca
    12421 gcacaaaaca agctctttta ctgcattagc atttacacct ggtgtattca tgacgatcgt
    12481 cccgttttca gaagcttttt caacgttgat cgtgttcacc ccaacaccag ctcttgaaat
    12541 tgctagcaaa tctggtgtaa gccattcatc tttcactttc gtactacgaa taactattcc
    12601 ttcggctggc aaatcatcta ttattttgaa atattcccct tgtaactttt ctatctcttg
    12661 ttctggaata gcatcaatca aatgaacgtg atacataaaa ccccctcctt actaacaagt
    12721 atctcgaaat ttctgcaatt agacaactgt ttaccatttg acttcctaga agcaaaaaga
    12781 gcagttagag cagagtaggc tgagtgataa aaataaggct atgacaagtt actgccataa
    12841 gccttatttt cgagagcaaa atattgaggg tgagatatct tgataaatgg tgttccgtta
    12901 gctgacattg ataataagac taaatttcaa aaaagttgaa aagcaaattt cgtcaatctc
    12961 ttcttatttc ttaaaactaa gtggcttttt cacaacctct ttttatctaa taaccactgt
    13021 ttccaactca actaattttg cccacgtttc aatttgatct gttgttagat ttagcgagac
    13081 aacggtatga tgaccgccac ctgcctgaat ccatgaatgg acaccttcat ggaaattcgg
    13141 tttagttttc cataacacac gtgcaacagg taaattaggt gcttcagtcg ttggttcaaa
    13201 ggcttctact tcattgatca gcagtttata atgcgtaccg aaatctgcca tcgatacgac
    13261 taccccttct cctgctttcc catcaaatac aagacgcgcc ggatcttctc tatctcccat
    13321 tgataaagga gaaacaacga ttcttggttt cgtcgcagca agcgtcggat ctacttccat
    13381 catatgggat tccaagattg cttcttggcc actagctagc tcgtaagtat aatcttccat
    13441 gaatcctgta tctttccctc gagccatgat tttcagcaac cgatcaatcg ctgcagtttt
    13501 ccagtcgcct tccccagcaa aaccgtatcc ttctgccatc aaacgttgta cagctagtcc
    13561 aggtagttgt ttcattccat acaggtcttc aaaattagtc gtaaaagcgt tatagcctcc
    13621 ttcttctaag aaacggcgaa taccgatttc ctgctgagct tgtactttta catgttcctc
    13681 ccatgtcttt tcttcataat caccatagtc gaaggtatac aattccttgt actcttcaaa
    13741 taattgatcg acttcttcgt ctgatacgcg atcgattact tgtacaagat ctccgatacc
    13801 aaaataatca acagtccaac caaattgaat ctgtgcttcc actttgtctc cttctgtgac
    13861 acccacgttt ctcatgttgt caccaaaacg agccactttt attccaaaat tatatgggat
    13921 tttagattat ctttttagaa gttcttgaat gtcggtatag cccgtgtttc cgggcttttc
    13981 cggcattttt gatattgtta gatacttaca aatgttctta ttacctctca ccatttcccc
    14041 ctcaaaagta gtaaatggag tagtaaaacc ggccttgtgt caggctgcca gccgttccat
    14101 ttctgccctt gcggaatcga atgtggcgtg tgcataatag ttcagcgtca tggtgatatt
    14161 ggaatgtccc ataatgtact gcaaggcttt ggggttcatt cccgcattgg ctaaccgggt
    14221 gcagaatgta tgacgcatag catggggcgt cgtcgttttc ggcaacgctt cttcatggct
    14281 cttgttgtac ttcttcacaa gcctgccaaa catcccgcca taatctaccg ccgtcatggg
    14341 atagccgttc tgtttgagaa acaggaaatt ggcatacccg tcaataatga acggctttgc
    14401 acctttgcgg ttttttatca ctcgctggaa cgcctgatac acttcctcat tcatggggat
    14461 ttttctgacg ccgctttggg tcttgggttc gtcaatatag taaccgacgc cggtatttct
    14521 caaaagctgg tggctcacga tgattacccg gttttcaaaa tccaaatctt tgtccgtcag
    14581 tccgcacagt tccgaaatgc gaagccctgt ccccagcaga ataacgattg cgtcataatg
    14641 cttttggtaa accttatcac cttgaataaa ggacagaaaa ctttcttcct gtgctggtgt
    14701 aagaggcacc tttggttccg tatcgtcgtc cagaacgtca ctaagctgga agtcaaacgg
    14761 gttttttcgg atgcaatcgt cctgtatggc ggtgtaaaaa gccgctttca gggaacgctt
    14821 gtcgttattg atggtcttat aagaaaggcc cttttctttc atccgaagcg cccattcctt
    14881 tgcgtcggac agcttcacac tgtcaatcgg gcagctcccc agccgatctt gttccagaat
    14941 acgcatcagc cgttcccggc ccagtttggt gttgtgcttc acattgcccc ggtgcctgat
    15001 ctgcttggcg tagagctggc agacggtcat tttcttgccg atggtgtcta tcccgtcgtc
    15061 aaggtctttc tggatttctt tctccttttc ccggagtgaa atatcctccc gtttacctgc
    15121 cggggtctta tccgtaggca ctaacttcca tgagtaaaca aactgcggtt ttccaaaggt
    15181 atcaacatat ttgtaagcat atcgtccgtc ttttctctgg ctctctccag accgcaaaac
    15241 gcgatttttg ctgtctcgtc ttttttctga catctcgtca tgctcctttc catgacggaa
    15301 agagccgcat atatgcttat aaattattat aacatatctg cggccctttt tcactattag
    15361 attgtgtcca aagtgtcaat tattttctca aactgcttgc gtttgatctg gatgcggttg
    15421 ccattcataa tgacccagcc agaggccgga ttttcctcgg ccagcttacg caatttgttt
    15481 tctccgatac ggaaatattt agacgcttcc tcaatcgtca gcgtgtattt ttcccaaata
    15541 ggcacatcat ggttcataat gcagccccct ttcacaaatt caaaggtttg tgtgatttag
    15601 gggcatagac ggacggctgc tggcacagct ccacgggact ttcacccccg cgtggttctc
    15661 acgcggccct acccattgcc tgcgacgctt ttaacgctcg gactgtggct ataagggagt
    15721 atcatagtcc tgcctgtacg tcgtcgcccg caagccgcca cgctcacatt gcggcgtggt
    15781 gttcctcgct ccgcttttcc cgtagggaaa agtatcatgg cgcaccagcc gtccggctcg
    15841 gcacagacag aatgtgtccg tatgccctat gatgcgccgc cgttatcttg cgggcatatt
    15901 tatcaaggtg cgatcaggcc accgggaaaa caccgaaacg gggaaagggt aagccgtttc
    15961 atgctgccgg ggccggttcg tcagttcgtg acgatagcgt ggatgagctt gatttccaga
    16021 cggcgcttca tggcctcgtc cagacacaca tgcggatagc cgttttcgtc atagagcgtc
    16081 cgggtacaca gcttgttcat gtaaccgctg taatactgca aaacgcgctc tacggctccg
    16141 gcatccccag cgcgggcggc ctcgatcacc gaaaggggca aaagctcaat gcccttgtag
    16201 ttcgggttct tcatccgcgt ctaacctccc ttcggcatca acgcctttag ctgtttccgc
    16261 agctccgata aggtatttgt cctgtgccgc tgaacggcac tccgggacat tcccacaagg
    16321 ccgccgatct caccatctgc catatccaga acacagtgca ggattaaaat actctgctcc
    16381 atgctgggca gcgcggcaaa ggcttcggca acaagctcat tgttgatatg taggtcatag
    16441 ccatgcgacg aaaacgtaaa gctgtcgctg gggtagtgat ctactgtaca gagcttgtcc
    16501 aaatctgcct gtgacaaaga gcttagtgac acttcacggt cacggcggcg cttcatttca
    16561 gccaagtagc ttttggcctc gttacgcagt accgtcttgc aaaaagcatc gaacatgcac
    16621 cgcgcttcat agtcgcgggg gatagcatcc atcttctcac cccctttctg tgggggactt
    16681 aggtggttct ctccctttcc gctaacaaga ctttgacaag gccgccagct acccgctaaa
    16741 tacctccttt ttgaaaattt ctcaaaaaat ttttttgggg acagccgggc cgcaaaagac
    16801 gacaaaaatc gcccggcagg tcgcaaacct accgggcgag aaaatgcttt gctatgctgc
    16861 tgatttacat ggtatagtac atactcataa ccggaatagc cctgtg
//
LOCUS       DADGHT010000060        16892 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.060, whole genome shotgun sequence.
ACCESSION   DADGHT010000060 DADGHT010000000
VERSION     DADGHT010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.060"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(451..1761)
                     /locus_tag="JX887_001822"
     CDS             complement(451..1761)
                     /locus_tag="JX887_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAX1257803.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="JX887_001823"
     CDS             complement(1773..3191)
                     /locus_tag="JX887_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1257804.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="JX887_001824"
     CDS             complement(3431..4999)
                     /locus_tag="JX887_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAX1257805.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="JX887_001825"
     CDS             complement(5003..5413)
                     /locus_tag="JX887_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAX1257806.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="JX887_001826"
     CDS             complement(5410..6333)
                     /locus_tag="JX887_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAX1257807.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="JX887_001827"
     CDS             complement(6330..7208)
                     /locus_tag="JX887_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAX1257808.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="JX887_001828"
     CDS             complement(7195..8532)
                     /locus_tag="JX887_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAX1257809.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="JX887_001829"
     CDS             complement(8535..9638)
                     /locus_tag="JX887_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAX1257810.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="JX887_001830"
     CDS             complement(9712..11220)
                     /locus_tag="JX887_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAX1257811.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="JX887_001831"
     CDS             complement(11186..11878)
                     /locus_tag="JX887_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAX1257812.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="JX887_001832"
     CDS             complement(11900..12874)
                     /locus_tag="JX887_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1257813.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="JX887_001833"
     CDS             13174..14046
                     /locus_tag="JX887_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1257814.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14628..16826)
                     /locus_tag="JX887_001834"
     CDS             complement(14628..16826)
                     /locus_tag="JX887_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1257815.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
BASE COUNT         4972 a         3535 c         2740 g         5645 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagctt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattaaacgg cgtttatctt
    14521 gttgattctg cggcaataaa atcagccagc agcaaaacat gaagtgctgt tttttgctgt
    14581 cctcttttat tgcttgaatc agatcacaag aaaaacagcc tcttgattca caaatatttt
    14641 tttcgatatt ctcccggcgt aatcgattcc ttctttttaa agaaacgaat aaaattttgc
    14701 ggatttcgat attgcaatct ttctgcaatc tcttttacgg agaggttagt ctctttcaac
    14761 catttttttg ctacctctaa acgatgattt tgaacaaaat caccaaattt ttctcctgtt
    14821 tcctttttaa atacattact taaatagtta gggttataat gcaacctatc agcgatcaca
    14881 tctaaagaca gatcacgatc atattctgtg tagacgatat gcataatatt ctccgacaaa
    14941 tttttaaatt catgatcagt gattgcttga gagcattctg tgattggcag aactaattgt
    15001 tctaaaacaa gtttttctag ttctttggga tgataattgt tcagtgcttt tacataaatt
    15061 tgtttcatgt tatcaaagtt ttttgaatct actcccaata actgtcctaa ttgaacgagt
    15121 tcattgatca agcggaccga aactacttcc cgactcaaag gatttttatt ttgtgcaaac
    15181 aatgcatcaa tcaattcatg tactaaattc ttcacttcct gatttccaga acgaatggct
    15241 tcaaacaatc gattttgttc ttctatcgga tatctaataa gtgttttttc atgagcagca
    15301 ggaacgattt cctgataaaa aataattgaa cttggaccag tatttacacg ataatacagg
    15361 gcttcttttg cccgatcaac cgattgcttg ctttcattca gcgtttcgaa ccggttactg
    15421 atgcctatac tgatagttaa attcaagtat tcttttacac gtttttgaat gagtcggcaa
    15481 tactccatga cttttttgct tgcttctgca tcatctttat ccattcgata aatagtggct
    15541 tgcatttctt cattcaaaac gatcggcagc attcgatttt cctttggcac aatttccgtg
    15601 atcatgttgt tgatcgctaa aagtagcaaa tcacgctccc caccgtgact atcttctaac
    15661 agatcgattt gaaccaaagc tgtataatag cagtcatttt gagaactata accaaattgc
    15721 tgcaaccgct gatctagttc tcgcctttct actcgatttc taaataaact aagtacaaat
    15781 agcgtttcca gctgtggctt ttgggtaact aagtgtgcac ttaacgcttc tttttctcct
    15841 atgatccgac tgactgattg agcgaccaaa tctagttctt tcccactgaa tccttttgat
    15901 ttaagattca gacgttcctg tatttgagaa atcggacggg caaatctgtc cgaaaataag
    15961 taggaaaaaa gaccaatgag tcctaccagt gttaaagaca ctgcaactag cccgattctc
    16021 agattgcgga tcattgcgcc aattgcacta gagtcaactt ctaatctgta aatccaatta
    16081 ttataatctg atttcagtac tatatacgtt ttatcttttt ctcttatcac tttcagctga
    16141 ttgtaatcta gatccacgtc cgttaataca gttggttgct ctttattttt tactgtctga
    16201 gtagtaaaaa ggttgccaac ttcgttttca atagaaagta tgtcttctcc actttcacca
    16261 acaacttgtt ctattgtatg tttctctatc gtagcaattc ccaatgcata tttttctttt
    16321 tcaaacattg gcaaagaaat caccatttcg attcctttgt ttttcttttg ccaaaataaa
    16381 ttatttttgt tatttatgta cttctgttga tacttttcaa cttcctcttc ggtcagttga
    16441 ctcaacgatc cattgattac tccccattta ccagccaaac tgactaaatc ataattatta
    16501 tcatccataa caatcgtttc tataaaattt agttctttcc tgatttcaga ataagtggag
    16561 taatctgtat atgtcagcgg atgcttgaat atgtccgaga aatttttggt cgaaccatac
    16621 gtagaaaacg aatattcaat cgttctaatt ttccattcaa cgttagtttt aacttgcctg
    16681 agcaaattct ttttgtctgt taaataactc gattcgatcg attcataggt attctggtaa
    16741 atgaataaac taaatcctat gacaagtacg gctcctaata aaaacatcgg taaaaatatt
    16801 ttataaaata ctgtactttt cttcattttc ttcctctcct ccttttaaaa taaaaggctt
    16861 tcatttttct gtaaaattga tactcatcta at
//
LOCUS       DADGHT010000061        16747 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.061, whole genome shotgun sequence.
ACCESSION   DADGHT010000061 DADGHT010000000
VERSION     DADGHT010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.061"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..356
                     /locus_tag="JX887_001835"
     CDS             <1..356
                     /locus_tag="JX887_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1257816.1"
                     /translation="GSSLSGGERQRLSIARAFLKNAPILILDEITASLDAENEKRIQE
                     SLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSEIYKNLIKKT
                     KLSEKFVYEKEAQSR"
     gene            879..1148
                     /gene="rpsN"
                     /locus_tag="JX887_001836"
     CDS             879..1148
                     /gene="rpsN"
                     /locus_tag="JX887_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAX1257817.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            1163..1342
                     /gene="rpmF"
                     /locus_tag="JX887_001837"
     CDS             1163..1342
                     /gene="rpmF"
                     /locus_tag="JX887_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAX1257818.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            1374..1751
                     /locus_tag="JX887_001838"
     CDS             1374..1751
                     /locus_tag="JX887_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257819.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            1772..1921
                     /gene="rpmG"
                     /locus_tag="JX887_001839"
     CDS             1772..1921
                     /gene="rpmG"
                     /locus_tag="JX887_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAX1257820.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            1945..2928
                     /locus_tag="JX887_001840"
     CDS             1945..2928
                     /locus_tag="JX887_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAX1257821.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            2958..3080
                     /locus_tag="JX887_001841"
     CDS             2958..3080
                     /locus_tag="JX887_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAX1257822.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            3098..4621
                     /locus_tag="JX887_001842"
     CDS             3098..4621
                     /locus_tag="JX887_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAX1257823.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            4645..4884
                     /locus_tag="JX887_001843"
     CDS             4645..4884
                     /locus_tag="JX887_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257824.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(5077..5712)
                     /locus_tag="JX887_001844"
     CDS             complement(5077..5712)
                     /locus_tag="JX887_001844"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAX1257825.1"
                     /translation="MVRHLFVDFQWSPEKISNRLKHEHMDFSISFITIYRAICNDLFD
                     TEPLSHGNKGLIRSLHHRGKTRHTKNHVESRGKICLTHSIHGHPKSADDRSDFGHWKA
                     DIVAGKTSGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEVLNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(5733..5951)
                     /locus_tag="JX887_001845"
     CDS             complement(5733..5951)
                     /locus_tag="JX887_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1257826.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            6260..7087
                     /locus_tag="JX887_001846"
     CDS             6260..7087
                     /locus_tag="JX887_001846"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HAX1257827.1"
                     /translation="MPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGISKPIPII
                     QAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVVEEEQDI
                     RGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVDLSKILN
                     TNLFNIDETSYSMGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFAHLTDKN
                     FPGNITRAKGFLWFAQHSDFSTIFETSGSHKSIESLNYWVASLPKIECQMIIQKNPN"
     gene            7276..7683
                     /locus_tag="JX887_001847"
     CDS             7276..7683
                     /locus_tag="JX887_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAX1257828.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
     gene            complement(7924..9264)
                     /locus_tag="JX887_001848"
     CDS             complement(7924..9264)
                     /locus_tag="JX887_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAX1257829.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(9540..9695)
                     /locus_tag="JX887_001849"
     CDS             complement(9540..9695)
                     /locus_tag="JX887_001849"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAX1257830.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLTDHHITHSMSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(9879..10082)
                     /locus_tag="JX887_001850"
     CDS             complement(9879..10082)
                     /locus_tag="JX887_001850"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAX1257831.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKMLNR"
     gene            complement(9992..10324)
                     /locus_tag="JX887_001851"
     CDS             complement(9992..10324)
                     /locus_tag="JX887_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1257832.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(10838..11029)
                     /locus_tag="JX887_001852"
     CDS             complement(10838..11029)
                     /locus_tag="JX887_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1257833.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(11127..11513)
                     /locus_tag="JX887_001853"
     CDS             complement(11127..11513)
                     /locus_tag="JX887_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1257834.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            12207..13412
                     /locus_tag="JX887_001854"
     CDS             12207..13412
                     /locus_tag="JX887_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HAX1257835.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKDFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTGNLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            13557..13862
                     /locus_tag="JX887_001855"
     CDS             13557..13862
                     /locus_tag="JX887_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257836.1"
                     /translation="MLNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDA
                     KISSYLFFLIHDEFMDYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            14479..>16747
                     /gene="esp"
                     /locus_tag="JX887_001856"
     CDS             14479..>16747
                     /gene="esp"
                     /locus_tag="JX887_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HAX1257837.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDI"
BASE COUNT         5763 a         2501 c         3164 g         5319 t
ORIGIN      
        1 acggaagttc actttctgga ggagagcgac aacgcctatc catagcacgg gcttttttga
       61 aaaatgcgcc aattttaatt ttagatgaaa ttactgccag tttagatgcg gaaaatgaaa
      121 aacgtattca ggaaagttta aatcgtttaa tacaagataa gacagtacta attatatcgc
      181 atcgcttgaa gtctattgaa aaggtaaata aaattgtagt gatggatcaa ggaaaaatag
      241 ttgatcaagg tactcatagt gagttgtatc gaaggtcaga aatatacaaa aatctcataa
      301 agaaaactaa actatctgag aaattcgtct atgaaaaaga agctcaatca cgatgatgaa
      361 ataggcttta aattaaccta caatttttgg gatatagtta taattctttt tcaaaaagaa
      421 taattttatt aaacagcatc taattttgaa tacacgaaag aatcagtatg attgaattag
      481 ttcacttaat gtctattctt ataatataag gaataatcaa agttttaaaa aattggcgat
      541 aaaccagtta aacataaaag attgaataaa aagttatagt ttctttcata ttgccgtttt
      601 aagtagagga aaagctactt aaaacggtat ttgtgtttga ttggactaat aaaagtgaat
      661 tcttattttt cagagcttaa actgcatatt cttttaaatg atttgattat ctctatgtac
      721 cgataaattc gttttcaaat agttatctat tcatatgagt tttatttcat gttatttatt
      781 gttgacaaga gcaactcttg ttggtaaagt atcagtgtca aaacgtaacg attacgattt
      841 gagatgtcta aatcaaaata aaaggagtat aaaggtatat ggcaaaaaag tcgaaaattg
      901 ctaaagcaaa gaaacaaatg gcgatgattg aaaagtacgc agataaacgt caggaattaa
      961 aagccgcagg agatcgcacc gctctcgcta aattgccaag agattcaaat ccgaatcgtc
     1021 tgaggcttcg tgatcagacg gatggtcgtc caagagggta tatgcgaaag ttcggtatgt
     1081 cccgtattaa gtttagagaa cttgcccatc aagggttgat tcctggagta aaaaaagcaa
     1141 gttggtaaaa ggaggaaata tcatggcagt accagcaaga aaaacatcta aggcgaagaa
     1201 acggttaaga agaactcatc aaactgtagt aaaaccagaa atttcatttg acgaagcgaa
     1261 tggtgattat agacgtagcc atcatgtatc tttaaaaggg tactataatg gaaagaaagt
     1321 aattaaagga gcttcaaaat agtttaatat ataactttta ggagggaatc aaaatggaaa
     1381 ttatttaccc acctttagtt gaagaaggat taaagtatta tcttgaaacg acccagcaat
     1441 cgctagataa atgcactttt tatcgttcga tggtagagag aggaattatt actgaaacgg
     1501 gtttaccgac ccaacaggca attgaaaatg gattagtcaa agattactat gaggaccaag
     1561 gcttatcatt tgatgatttt ttaagaatct atccaatttt tgaagagtat gacgaggagt
     1621 tatttcaatg tattgatggt tattgggaga tacctgttga tatgaaagaa aatttagttt
     1681 cacaattgga atctggcgag ttaacttttg aagatgcaca acaaattcaa gcatatcttg
     1741 aagatcgata agtattgaag gaggaagatt tatgcgtcaa aatattattt tggaatgtgt
     1801 cgaaactgga gaacgtctgt atctcaccag caaaaataaa cggaataacc ctgaacggtt
     1861 agaattaaaa aagtattcgc caaaattgcg cagacgggca attttcaaag aagtgaaata
     1921 gctaagtggt aaaaaggtga caaaatgggc ataccagtta caatcgtttc tgggttttta
     1981 ggggctggaa aaacaacgct aatcaatcaa gccttgcaag tctcacccta ccccagggaa
     2041 gaaattatta taattgaaaa tgagtttggt gaagttggga ttgatcacaa attattagtt
     2101 catagcgagg aacgggtgtt acaactaaat aatggatgta tgtgttgcag tcttcgcagt
     2161 gatttattag caatattgat ttctttactg gaaacaatag aagaacatca acaaccaatt
     2221 tcacaaatca tcattgaaac tacaggtata gcagatcccc aaccaatcat tcaaacactt
     2281 ttaacagcgc ctcaactaag aggaagagta tatatcgata gtttattgac tgttattgat
     2341 agtgacagtt ttgaacttat tgaaagagaa ccacaagccc ttaagcaact tgtcatagca
     2401 gatcgcattt ttgtgtctag aaaacaaaac ttgaatttat ctgcactaaa aaaattacag
     2461 agagaaatca aaagtattaa ccctttatcc gatattcgaa tgttcacaca tagtgaaacg
     2521 attcaaaaaa aggattttta taatttggaa aaattcaatc atcccttagt ttttgaaagt
     2581 gattcatcag aaaatcacta taatggcaaa cactatcatc aacatcatca agaacatgag
     2641 tttaaatcaa ttctcttaac ttcagatcaa gacataaaaa aagatttttt attccaatta
     2701 attgaccggc tgattttaac caaccaaggg agcctgtatc gttttaaagg attgattgct
     2761 ttgcaagatc aagattttat agttgccata caaggggtaa acgaacaggt taattttcaa
     2821 tacaccactc gacaaaaaga ccaaaccact attattctaa ttggaaaaat gttggatgaa
     2881 gaaaggatca aacagagttt tgataaatta ctggcggaaa gcaaataatg ataagtattg
     2941 attaggggta atttctaatg gagaaaacgg atatatctag tgcatatcga cgacttaaaa
     3001 gcccgaatat caaaactaga aaaagggcat taaaaattat caaagaacat aaacaaaata
     3061 aaatgaagaa attagcataa ttaaggaagg aaaaagaatg aagaaaatca gtgtaggact
     3121 tattgggata gcagctctag gattattggg agcttgctcc agcactaatg atgcaaaagt
     3181 atcgaatgat aaagatggaa aattagaaat tgtaacaaca ttctatccaa tgtatgattt
     3241 caccaaaaac atcgtcggcg atgaagcgaa cgtggattta atggttccag cgggatcaga
     3301 acctcatgac tatgagccct cagctaagga tatggcaaaa gctcatgatg ctgatgtttt
     3361 tgtatatcat aacgaaaaca tggaatcatg ggtaccaaaa gctaaagaaa gttggaagaa
     3421 agctgggcct aatgtagtag aaggaacaaa agacatgatt ttattgccag gtagtgaaga
     3481 agaagatcat gatcacggag aagaagatca ccatcatgaa ctagatcctc atacgtgggt
     3541 ttcacccaaa atggcaatta aggaagtttc aaatatcaag gatcagttag ttaaattgta
     3601 tccgaaaaaa gcaaaagtat ttgagacaaa tgctgaaaag tatttgacta aactgaaacg
     3661 gttggatgct gactatacca ctagtcttaa agaagcgaaa caaaaaagtt ttgtgacaca
     3721 acatgcagcc tttggatatt tagctttgga ttatggattg atacaagttc ctattgctgg
     3781 actaagtcct gaagaagagc catcttctgg tcgattagct gaattaaaag agtatgttaa
     3841 aaaaaataag atcaattata tttactttga aaagaatgct aatgataaaa tcgcaaaaac
     3901 tttggccaat gaagctggga taaaattgga agtattgaat cctcttgaaa gtcttacaaa
     3961 agaacaaatg gataatggtg aagattatgt ttcagtaatg gaagacaatc taaaagcgtt
     4021 agagaaaaca actatggttg ctggtgaaga ggtagttcca gaaaaagaag cgaaggatga
     4081 aaagacagtt gctaatgggt actttaaaga tgccgatgtg aaggatcgcg aattgagtga
     4141 ttatacaggc gaatggcaat ctgtttatcc gttgttaaaa gatggaattt tggatgaagt
     4201 tttcgattac aaagcaaaac tcaataaaga catgacagct gccgagtaca aagattatta
     4261 tactactggc tataagacag atattgatac tatcaacatt aaagacaaca ccattgattt
     4321 tgtagtcaac ggtgaacatc atcaatacac atacaaatat gttggataca aaattttgaa
     4381 ttatgaaaaa ggaaaccgtg gtgttcgttt taattttgaa actgatgatg caggtgctgg
     4441 tcgttttaaa tatattcaat ttagcgatca tggaattgca ccaagtaagg cagagcattt
     4501 ccatattttc tttggtggag aaagtcaaga aaaactttat aatgaaatgc ataattggcc
     4561 tactttctat ccagcttcat tatctgagca tgagattgct caagaaatga tggcccatta
     4621 aaatccaatc tttggaggaa atacatggta agaaaagtat tattgtctat ggattccaag
     4681 aatattgatg cttatcggcg ttatcaattt gcaaagcaaa tgagattaaa tgggagtaca
     4741 ttagctgata ttgctgcaac tttacatgtt agtattgaca cagttcatag agtattaaaa
     4801 cgggatcctg attgttgttt tatcaaggtc aatactggaa gaagtagacg tttagcaaaa
     4861 cggcataata gcttggccaa ttaattgata ataccagagt agatcatttt tcccttattt
     4921 ggatttgatc tgctttttat tatttcttga attgtcaaat caagcgcaac actttatcaa
     4981 agaagacttc ataaggtgtt ctccaatcta aacactttct aggtctgtta ttcagttttt
     5041 caatcatctg atttatcgtt gagttatcta ccgtagctat ctctttcgat tttggcaagt
     5101 attctcgaat gagtctattc gtattttaat ttgttcattg ttgccaaggg catgaggatc
     5161 tggaaaataa aagggcatat tattcaatac ttctgtaact gcgaaatgat tggagaattc
     5221 ttttcctcta tctggagtga tcgttttgac cgcctcattt ggaatactgc ttaaaagttc
     5281 aatcattttc tcgctcacat aagcggcttt ctttctgggg accttctttc ctgctaaaag
     5341 gaagcatgat tttctgtctg tcaaagtcac taaacaagta ccactagttt tgccagctac
     5401 aatatcggct ttccaatgac caaaatcact tctatcatct gcggattttg gatggccatg
     5461 gatcgaatga gtaaggcaaa tcttcccacg agactcgaca tgattttttg tatgtcttgt
     5521 ttttcctcga tggtgcaatg aacggatcag gcctttattg ccgtgtgaga ggggttctgt
     5581 atcgaaaaga tcattgcaaa ttgcacggta gatcgtgata aaactaattg aaaagtccat
     5641 atgttcatgc ttcaaacgat tcgagatttt ctctggcgac cactgaaaat cgacaaataa
     5701 atgacgaaca attgaccaaa ctcacggatc atttagaatg tgataacgtc cgcatttttt
     5761 tcttcgataa gcataatttt tttccgcttt ggaaggtgat tagttttttt cttgtttctt
     5821 ctcagttcat gtaaaatagt aaacgggcta tgctgaatgt cgttgccaat tatactaata
     5881 gaaaatcctt cttcgtgaag cagaaagatt ctttctcgtt tgagtatagt aagatgacaa
     5941 tactggctca taattatttt ccttctagga gtgttctcga caaacttata ctagttggat
     6001 atcgattatg actcattttt atgtgttgca cttaaagtgt aaattcaagg tatagaaaga
     6061 ggttccctat gaaaaaatac ctattacaat cttaactggc tatcttggtt caggaaaaac
     6121 gatacttcta aatcatattc tgtacggtga tcacggaaag gaaattgctg tcattgtaaa
     6181 tgacataggg gaagtaaatg ttgatggggt attagtcgac aagaaaggtt ttaaaagaac
     6241 tggagaaaaa cttgtttcga tgccgaatgg atgcatttgt tgtacattac gcgaagattt
     6301 gattgttgaa ctagatcaat tagtgcaatt ttctgacttg aatcaaattg ttattgaagc
     6361 ttcaggaatc agcaaaccaa ttccaattat tcaagcaatt atattagcta aaaacccttt
     6421 agacattgat ttgacccaac gattagagat tggtgccatt attatagtag tggatgtaaa
     6481 acgtttttgg gataatttcg aaacgggtga aaagattcag gaaagaaaag ctgaaggtaa
     6541 tgtagttgaa gaagaacagg atattcgtgg cttgttaatt gatcaattcg agtgttgtaa
     6601 catattactt ttaaataata gtgacttagt gtcaaccaag acgatttaca aaattaacgg
     6661 tctaattgct aagttacagt ccaatgccaa aataattagg acaattaaag gtgaagtaga
     6721 cttatcgaaa attctaaata caaatctttt taatatagat gagacttcct attcaatggg
     6781 ctggttcaaa gagttagagc ttggctatca aaatcatatt cctgaaacag aagaatatgg
     6841 tatctcaagt tttatctatc gaaatcggtt actccttgac gcacaaaaat ttgcccatct
     6901 tacggataaa aattttcctg gcaatattac aagagcaaaa gggtttcttt ggtttgccca
     6961 acatagtgat ttttcgacga tctttgaaac atcgggtagc cataaaagta ttgaatcatt
     7021 aaattattgg gtagctagtt tacctaaaat tgagtgtcaa atgattatac aaaaaaaccc
     7081 gaattgaagg aagcctggca tccgttgttt ggtgaacgca ttaataaact agtttttatt
     7141 ggtatgaaga tggatcaaca atgtattaag gaacaacttg agggttgttt aactgattct
     7201 cttaatgcag ataatttccg aaaaatttca ccatttccat ggaaaaattc taatatgttt
     7261 agccagatat cgttaatgaa atttttaaga aaagctggtg tcaagatagg cgatgtcata
     7321 attattggca ttttgattat tccctctttt attcccttat ttgtattctc tatagaaaag
     7381 gagaatgaaa caactgaaga tgctatcaaa tatgccatcg ttcaaattga tggcaaggaa
     7441 atggatcgct tcgatttgga taagatcaat cataaactcg tgaattatca tcctgcgaag
     7501 ggacaatata atattgttga gattaaagat ggaagaattc gagttaaaga agataatagt
     7561 cctgatcaaa tcgcggttag aactggatgg atctcaaaac ccggtcaaac gagtatttgt
     7621 ttaccccata agttagttat tagtattgag aaaaaagaaa gcaaagatta ctacatttac
     7681 taatctggaa atagatgagg aggtttttaa taagaaaaag atattattat taataatagc
     7741 aggggcttta ttaagtgtgt taagcgcttg tggacaagaa aaagaagcgg tgacaacagg
     7801 cacaagtatc tttaacggga cctgcaatgg tttagttaac agtcggttag attacttatt
     7861 ttggctcttc gtcaatgagt gttggtgaag aaattcaata gaataatcga gatactcaca
     7921 cggctagaca gctatcttgt ctagccgtgt tgttgttctg gctttagtca gttgggtagt
     7981 gttcttagtt ttcttgaaat attttcctcg atataaaaag attcgttctc ggtagttttg
     8041 aaagtttcta aagccatagg caattcgttt tagtactttg atatggttgt tcaaacattc
     8101 tatagggccg ttggaatagg gaactcgcaa cgctcgtttg atttctgttc gatatttctt
     8161 gaaggtcgtg aacactggtt gatagtgctc tggcaactcc ttgtagtctt cttttaggag
     8221 cgcgacgaat tcaggaacat cttgtcttct gatagcggaa agaaaaacct ggtagacttc
     8281 gtagcctcgc tttaaggagt catcataata taatagccga tcgactatct ccgcttctgt
     8341 cagatgatct cgaaatgacg gacgccagta gcgatgctga ccattcaatt cccacgcatt
     8401 cttttgaagt agtctccagt atttctttaa gtgcttcgac cgacgatccc cttttttaaa
     8461 ggtcttcatt acttgaattc ggtggttggt aaaggcccga ccgatgtgtt ggctaatatg
     8521 aaagcgatcg gcgacgattc gggcattcgg aaaacactct ttcaccaatg tgcgataggg
     8581 tgtatagaaa tctgaaacca ctagacgtac ttgttcacgg acttttctag ggtagcgcaa
     8641 gaaatagtcg cgtaaaggat tgagttgccg attttccaca atatcaatca gttgatgggt
     8701 cttgccgtcc atcatgacaa agctcatggc tcccgagacg tttttcaccg atttgaattc
     8761 atcgaaacac accacttctg gtaacggctg gttcaaagaa acggttttag gccgaaggct
     8821 gcgaagtatt cgaatgacag tggtcggaga aatgtgcttc atacgtgcaa tcaaagacat
     8881 agaaataggc tcacttaata gctcaagaat ggcttgtttg actctgcggg caatggagca
     8941 gcgacgatcg ctaactgaat cttctgctaa aaaagtcttt ccacagtgtt tacatttgaa
     9001 gcgctgtttg ttaatccgca caatggtctt gtagttactg acatcattca ataagatgga
     9061 tacttttttc cagccccatt taatgatcgt ttgcttattt tgatagtggc aatggaagca
     9121 ttcctctggt tgataggtca atgtgccatc aaaaacaaaa catgtttcgt cattaatgcg
     9181 ctctttgcga aaggcatctt catgaaaggt aagatttagg tctagaatat ctagtaactc
     9241 tttggtaaac tctgaatagg acatcttgaa acactccttt gaatggtttt cgtcgacttt
     9301 attctaaagg atttcaaggt gtctgtttgc gtttattaga aaaaagaaaa agtattggca
     9361 acagaaggcg tcaccaacac tagatattat agatccctta ttttcttcgc ttcaaattgt
     9421 caaggagtca tcataaattt tgtatggatt cttttgtttg ggtagtagtc ttctaaataa
     9481 tcttggatta acaccttcat ctctatttta cttttatatt tgttggagtc gattaattct
     9541 catttgattg atcgatgaaa cgcttcaatt actgcattgt caacaggagt cccagtttgg
     9601 ctcattgaat gtgtgatgtg gtggtcggtc aacagctctt gataaataaa agaccgatgc
     9661 tggctacctc tatcggaatg aattaccgta ggcaattctc cttaataaat ttgtaatgga
     9721 cggacgacaa tctctttttt catgtgtgaa tccaccatat agtaacgtag aatacgagtt
     9781 gctaagtcaa tataggtgga caaatagagg cgaccgtcat tacatggaat gtaagtaata
     9841 tccgtcaccc aaacagcatc aatttggttc tgttcaaatt atcgattcaa catttttttt
     9901 accatttctt tgattgtttt ttctctacca tgagaagatt tgcgtcgatg aaatcctctt
     9961 gtgcataaat tcatttcacg cataagaaca gctacaacac gtttattgat ttcgattcct
    10021 tcatcgtaaa gtttttgagt gatccctgga gatccgtatc gatctttgtg ttcgtagaac
    10081 actcgtcttc ctcttttagt cgtttatttt cctgttcaag aatgtagaaa tctgctttat
    10141 caggtaatct ttttccttgt ccagcaaaag catttttccc gtatcgacga tattctgaaa
    10201 cccatcggga aattgttgga cgagagatat tgtattcttc agcaattttc ttggtagtta
    10261 cttttttctc aaggatatcc tgtgaaatct ttagtttaaa tttacgatca tatgtttttt
    10321 tcaatagagt tcattccttc cggtaacgta actgatagtc aagaaaagtg tatcatagcc
    10381 caacttagta tcagggtttg tcaactaaac tgtggaagtt gatagataag agtttttaac
    10441 aaccaaaatt ctcttgacta tttttgaaat cagacaaatt ttgattggac acatagttga
    10501 ataaatctac cgtcgttacg gaaggtaaat cgcatgcttt tcaattctag aggagaagtc
    10561 ctcgttgaag taccatggcc cagttctgga ttcgacctcc tgcccacttc gtacgtaaat
    10621 aaagtaattt taggagtgag actgtgacaa aagttatttt taagctaaaa acgaattaaa
    10681 aaacgttaat aattaaaatc attcgtttta gattctatga atcattatag aacgctgtaa
    10741 aatcgatact ttataattat aaagaagatg gcttcaaatt tattgttcga aatttgaaac
    10801 tatcttttta cttatgtcac agactccctt agttgagtta ttctttaatt tcgaatttcg
    10861 agatagctag atatattgca agcatacatt cttgataaca atcttgatca tattttccag
    10921 ttctccagga ttgcttatgg accaaagcgc taaatctttt gagaatggcc acaactgctt
    10981 cttcatttcc attctttgct aaaatgaaat cttcttttaa agtattcata aatttacctt
    11041 cttcccatga acttataatc tatttatttt ttggggaagg aggaggacga gcaaagaagc
    11101 atacaaaatt agttattatg cagatattaa accagcattt tttgaatttt tttgtaaagt
    11161 cgatgtttta aatttgtcgc accctgtctt gtaataccca gaacctttcc aatttcttta
    11221 tcagttttat taaagataaa tttttcgata agaaaaattt gttcaggttc tttcaacaaa
    11281 ggaaggattt ttgctaattt tatatcttca acaaggagag tcacatttaa aacattaatc
    11341 ggttgtttaa attttatagt atctttagta aacaaatatg gtgggagttg atcaagttgt
    11401 tcatgttttt gaatttcttc ttgtttttta taataagtat tagcggtgtt caaaatgacc
    11461 ttttcaaaga atcgaatcaa ctgggcattt acgcgttcgt cgttatctga catattgcac
    11521 acctcctcca ttaagattta aagggaaaag aggcaaaaaa cacgaaaaga agctaatgca
    11581 attatgctgc gctgcgaata acttctataa gctcacatgc attgatagga ctgctgatgt
    11641 ttattttcaa aaatgttttt ttagttgata atggatagtt atctttatac ttagaaaaga
    11701 aaattcatat atcttcttaa atatcaaaca tgtccttatg gctaagaaaa tgtcttgagc
    11761 tttttacgta taataaatct tttctaaaac ctccttttgg ataatattct tattcgtgta
    11821 tagattgtat tttttatttc ttcccccttc ataattaaca actagaaaag agttcgaata
    11881 gacacgtatt tgaacgaaaa tttttattgg attcccaaat tggagtattt agaaacgaaa
    11941 aattcctatt atctgtatag tgcttagata ataacggatc ataataatta ttgtctttga
    12001 actagatata tgtaaatagt attcatcatg atgaaaaatg atgagttctc ggtgataaaa
    12061 tgtacttttt acggtggaat atacatgaaa gcgataagtg gatattttat aatgaagtaa
    12121 gttagcttat tttgacagag gaatagtatt ttagataacg tataaaatac tatttaatga
    12181 tgtagaaagg aaagagagaa acaaaagtgt tttcagataa agaagtctta ttaaagtctc
    12241 ttcatgtttg tttaaagtta cctatcgtgg tttttaattc cgaattcagt attataaaag
    12301 agtatcgctc agatagaact acttattttt tttatgatta taaaaagtta ctaactgata
    12361 atattaaaaa aactaaagat ttccatttct ttactggtga ttttaatgag atgtttcttc
    12421 tatacatgtt taaaaccaga tattacttat ttggtccatt tagagcaaat aatattgata
    12481 aagatttttt taaactaaaa atgaacaatt tgaatgttgc aatggctgat agagaacgac
    12541 tctataattc attgcaaaat ttgactttgt attctttagg agacattcga gatattctga
    12601 ttttagttca ttattttttt actggaaaaa tagaagatct attccatgaa ccgttaattg
    12661 aatatacagg aaatctaagt aaaactatcg agcaaatcaa aatagataat ctgttatcac
    12721 aaaattacga tccagaaata tatctgtttc tttatgaaaa taaaatactg gaatatgtta
    12781 aaaatggaga tattcgaaat ttagaaaaca tggtttttaa tctgagtaat ggaataattc
    12841 caagtgttag tggagatacg attcggtctg aaaaaaatta ttctatcatt gtttttgaaa
    12901 agttagcaca aacgtctata acattaggaa tggatataat agaagcgtat caaagtagag
    12961 atgctttgat acaagaaaac gaattagctg tatcgttacc tgaggtctta aaagtgaggg
    13021 attctgggat tgtttattat actaaggaaa tcggaaaaac taagatagag catctttctc
    13081 ccttaatttc ttctgtcgtt caattcatcg gcttaaatat ctataaaaga attactgtaa
    13141 aggaaatagc taattatttt tctgtaagtg aaactaaatt aagagaaagc tttaagaatg
    13201 aaatgcatat tacgatttat aattatatct ctaagcgaaa aatttctacg gctaaaataa
    13261 tgttgaaatc aaaccatact atcagtgaag tttctttagg tttaggattt tcagattctt
    13321 cacacttttc gagagtattc aaaaagtacg caggtgtatc tcctaagcaa tatcaattag
    13381 gtttagtgga taatttcaac aacattagct gagaggtttt attttattat gagactatat
    13441 catttacgta gtttggagga gttgaggaaa ttggatttta acaaaaaatt ttttgggaaa
    13501 tttctgattt gagttgtttc gtagaatctg agcgtctaag taatggtaat aatagtgtgt
    13561 taaatgaata tgacaaagta gtaattaata aagtaaaaag tttatgtgaa gaagctagag
    13621 aatctatcag tcatattaat ggtagcaatt ttaagcaaac attatttaat ctgattaagc
    13681 tagatgctaa aatatcaagt tatttattct ttttaataca tgatgaattt atggattatc
    13741 aaaaattgga tcagttaatt gaaagagaaa gctgggaaga ttattacgtg ggtctaactt
    13801 tttcagaaaa gttaaacaac tacaagttaa tagattataa gtatttgagt gaaagcaatt
    13861 aattattcat gtagagtact agacacttta aatatggaca attcaattat aaagaaaaag
    13921 aatcaataat ttaatgaggc tgtgacaaat gtcatttttt gtttcgctaa aaacgagtga
    13981 aaaaatgttg ataactccaa tcattcgttt aagattctag gaatcattca ggaatgctgt
    14041 gaaaccgata ctttataatt ataaagaagg tgatttcaaa ttccgaagaa ggaatttgaa
    14101 gtcacctttt tacttatgtc acagtctcat tcagtaatgc gggataaggc tccttattcc
    14161 gctatttgaa tactctgaag tttaatctaa gaaagagtaa tattttgaaa acatgcttca
    14221 tcgcatagaa atgaacttaa tttcagaaag aatacataca tatcttttta tatgttttca
    14281 gctgctgaat ggttaaaaag cacaaatatc cgaaaaaaac atgaagaaat gtactttttt
    14341 tgttgtaatg tgcatgaaat tctttaagta aactagttaa cataagttta gtaagattcc
    14401 tattctgtga ataatacgta tcagatttat cttttattct tactaagaaa ataactatta
    14461 agggagttga tttgaataat ggttagcaag aataataaga gagtatttct agaaaaaaca
    14521 aagaaacgag tattgaagta cagtatcaaa aaattaagtg ttggggttgc atctgttttg
    14581 gttggtgttg gtcttgtctt gggaacaact gaactagttc aagcacaaga tgaaatttct
    14641 ccaagcaccc cacttgaaac agcgataagc tccgtacaag taggtgacaa agtagcttcg
    14701 gggaatactt ttcaggagaa tcctggttat acgaaaaatt ataacttttc ggatttacaa
    14761 tttagtcctc aagaactaac tggagacaca ctaaaaggca atacaattgg atttgaagtt
    14821 tacggaaaac ataatattgc agcatcaact aaaaactggg aaatccgtct tcaattagat
    14881 gaacgattag ctaaatatgt agaaaaaatt caggtcgatc caaagaaagg aattggatct
    14941 tctagacgga cctttgtaag aattaatgat tcgctgggta gacctacaaa tatttggaag
    15001 gtcaattata ttcgtgcaag tgatggatta tttgctgggg ctgaaacaac tgatacacaa
    15061 actgctccta atggggtaat tacgtttgaa aagagcttag atgaaatttt taaagagata
    15121 ggcatagaca atctcaagac cgatcgttta atgtatcgaa tctacttggt aagtcatcaa
    15181 gacgatgata aaattgtacc aggtattgat agtacgggct actttttaac agattcagat
    15241 gatttctata atagcttaga tgtatctgaa aataatcctg accagtttaa acatggatca
    15301 gtaagtgcaa aatatgagga acctaatact caaacaaaag atggttcagg atccacaggt
    15361 gctaatggag ctataatctt agatcataag ttaacgaaaa attataattt ctcatattca
    15421 gcttccgcaa agggcacgcc ttggtatgct aattacaaaa ttgatgaacg attagttcca
    15481 tatgtagcgg gtatacagat gcacatggtt caggctgaca aagtaacata tgatgtttct
    15541 tttgaatcag ggaaaaaagt ggctgattta gcaattgaac ggcgcaaaga tcatgaaaat
    15601 tatggtgtag gttcaattac tgataatgat cttaccaaac ttattgattt tgctaatgca
    15661 agtccacgtc cagtcgttat tcgatatgtt ttacaattga ctaagccatt agatgaaatc
    15721 ttagaagata tgaaagcaac agcacaagtt gaagaaaata aaccatttgg tgaagatttc
    15781 atctttgatt cttggttgtc ggatacgaat aaaaaattaa tccagaacac ttatggaaca
    15841 ggttattatt atttgcaaga tattgatggt gatggaaacc ctgacgataa agaagagagc
    15901 ggagacacga atccatatat cgggaaacct gaattagaag aagtatatga tgttgacaca
    15961 acagttaagg ggaaagtatt catccacgag ttagcgggaa caggtcacaa agcccaactt
    16021 gttgataaag aaggtactgt attagcagaa aaaactatcg ctccaaatga aaaagatggg
    16081 gctccaattt cagatactgt agaatttgaa tttacgggtg tagattcaag taaattaatc
    16141 gcgaaagatg aattaaaaat ccaaatcgtt tctccaggtt ttgataaacc agaagaaggt
    16201 tcaaccgtta ttaaggaatc accaaaagcg gttgataaac aaaccgtggt agttggattt
    16261 aaaccagatg ctaaagaatc aattcggaat aataaaaact tacctgaaga tgcagagtat
    16321 tcatggaaaa cagagcctga tacttctaac gttactgata gtacgaaagg tattgtaact
    16381 gttaagatcg gaaatcgaac tttcgacgtg gatgtagagt ttgctgtaaa agcttctcaa
    16441 gctatggaaa atgatgcaac atacgtacct ataacaacaa ctccagaaac gacagttcaa
    16501 agtggaaaac ctacatttga taaaccagat gttcctttag ctaaagatgc cttttcaatt
    16561 ttagatgtct ataataagga cttcggtaat gcaagtgttg atgcaaatac tggtattgtt
    16621 acattcactc cagctaaagg tgtaggagaa tcggagccga ttactggaac aattcctatt
    16681 aaaattgttt accaagatgg ttctgtaggc acgaccgatt tagcagtaac tgtaagtaaa
    16741 gatattt
//
LOCUS       DADGHT010000062        16726 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.062, whole genome shotgun sequence.
ACCESSION   DADGHT010000062 DADGHT010000000
VERSION     DADGHT010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.062"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(39..1241)
                     /locus_tag="JX887_001857"
     CDS             complement(39..1241)
                     /locus_tag="JX887_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1257838.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            1358..1873
                     /locus_tag="JX887_001858"
     CDS             1358..1873
                     /locus_tag="JX887_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAX1257839.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(2072..2518)
                     /locus_tag="JX887_001859"
     CDS             complement(2072..2518)
                     /locus_tag="JX887_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAX1257840.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(2565..4043)
                     /gene="msr"
                     /locus_tag="JX887_001860"
     CDS             complement(2565..4043)
                     /gene="msr"
                     /locus_tag="JX887_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAX1257841.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(4397..5026)
                     /locus_tag="JX887_001861"
     CDS             complement(4397..5026)
                     /locus_tag="JX887_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAX1257842.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(5010..5474)
                     /locus_tag="JX887_001862"
     CDS             complement(5010..5474)
                     /locus_tag="JX887_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAX1257843.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(5961..7229)
                     /locus_tag="JX887_001863"
     CDS             complement(5961..7229)
                     /locus_tag="JX887_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAX1257844.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(7460..8197)
                     /locus_tag="JX887_001864"
     CDS             complement(7460..8197)
                     /locus_tag="JX887_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1257845.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(8264..8833)
                     /locus_tag="JX887_001865"
     CDS             complement(8264..8833)
                     /locus_tag="JX887_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAX1257846.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            8961..9833
                     /locus_tag="JX887_001866"
     CDS             8961..9833
                     /locus_tag="JX887_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1257847.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            10175..11047
                     /locus_tag="JX887_001867"
     CDS             10175..11047
                     /locus_tag="JX887_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1257848.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            11044..13002
                     /locus_tag="JX887_001868"
     CDS             11044..13002
                     /locus_tag="JX887_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1257849.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(13253..14104)
                     /locus_tag="JX887_001869"
     CDS             complement(13253..14104)
                     /locus_tag="JX887_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1257850.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            14227..14694
                     /locus_tag="JX887_001870"
     CDS             14227..14694
                     /locus_tag="JX887_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAX1257851.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(14957..15439)
                     /locus_tag="JX887_001871"
     CDS             complement(14957..15439)
                     /locus_tag="JX887_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAX1257852.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(15539..16402)
                     /locus_tag="JX887_001872"
     CDS             complement(15539..16402)
                     /locus_tag="JX887_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAX1257853.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         4990 a         3471 c         2981 g         5284 t
ORIGIN      
        1 acttgatgca ggacagcttt ttcacaacct ctgatttctt attcttcttc atttgtagca
       61 aaataattac ggtgataaat gatacaacat acactgataa gaacaatggc acctgcaaaa
      121 taaaacgcat agctttcacc aatatgttca ccaatcacac ctgcaataaa tggtgctaaa
      181 gctccaccga aaaagcggac aaaactatag ctggacgaag caacgtttcg ttgcagacct
      241 ggtatttcca tagcaatcgt cgtcaacagt gtattgataa ttccttggaa aaatcctgct
      301 aacacaatgc tgatcggtac aaggactggc atagaagttc cagctcctaa taacagcaaa
      361 caaataatga ataagacaaa tgctgctaaa attgtccgat aagtcgtaaa cttccgctca
      421 agagccggtg caacgaaaat cgaagcaata gccagaagca caccccagcc aaaaaataca
      481 aaaccgactt ctaattcaga atagccaatc aataaaaatg gcgcatacgc aagtaaagta
      541 aagaatccga aattatataa caatgcgatt agtccaactg aacgaagttt atgattgctt
      601 aacgctttga caccttccca aaggcctact tttctctttg gtttctcagt ttcaggtaaa
      661 agtaccgcta gggctataaa accgcaaaac atcaaaaatg ctaccccaaa aaatggataa
      721 cgccatgaac cactgcccaa gaccccaccg actagagggc caacagccat tccgcagcca
      781 agtgctgctt catacatcat gattgctttt tctgtgttac caactaaaat actgacgatc
      841 gttgctaaag cagtagagac aaataaagca ttcccgacac cccagccggc acgtaaccca
      901 atcagcattc cgatattccc agataatccg ccaagaccag cgaatacaac gatgataaac
      961 aatcctgtca tcaatgtttt tttcaaaccg atccgactag ataagaaacc tgtaaatagc
     1021 atcaccacac cagtgactaa catgtaacta gtaaataaca gggtcgtttc agctggcgta
     1081 gcgtttaact gtgcagcaat cgtttttaag attgggtcta ctagacccac tcccataaaa
     1141 gcgatcatac aggtagctgc tacaactagc gctgaacttt tcccctttgt ttcttcattt
     1201 gtttgttctt gtatatctat ttgattctcc aatatttcca tccctttctc tctattagca
     1261 tcatacatga tttattttac atgtaaatat gcacatgtaa aacgtggaaa ctttactgtg
     1321 atataataaa gaaaataaga cgagaggtag gatttttatg aatactttag cctatatatt
     1381 attatgcgtg cttttatcca aaccacgttc tgggtatgaa ttgaagcagc tgatcacaat
     1441 tttttgggaa gcccatcaca gtcagatcta tacaacgctt gccaagttag accagcaggg
     1501 ttatgtgacc gttttggaca aagacgagca ctctcaaaaa aagatctacc acttgactga
     1561 tgaaggacgt gctcttgtag aggaatggat caaagaggaa actcccgctc ctacgcaaaa
     1621 agatgaattt ctagcaaaaa tctatgcttt ttcgacgctc gataaaacaa cagctactgg
     1681 actgctattc actagagaac aacagctgaa caaaatcatg caaaaaaatc aaaaaaaatt
     1741 gaatgacctc tcgctagaca agaaacaaga atttggacgt tatgttgtga tccagcgcag
     1801 aattatgctt tgtcagcagg aactccaatg gtgtcagcaa gtaagagaac aaatgcagca
     1861 gttttttgag taagggataa acagaacctt tctagaaata tctattgaag agcaaattat
     1921 cttcaataaa agagcaatac agttggaaaa gaaaaagcga tccgaacgac aggccaaaac
     1981 ctatcgttcg gatcactatt tttctagaac tgcattcaag agactatgac aaaaagcatg
     2041 ccaaggcctt ttttcaaata acagtgttcc atcattcatt actttgaatt gcttttagca
     2101 cacttcttga aagcgggcca acgatgatca actgcaacgg taaagcggca atcacattca
     2161 ttttccaagc attcatataa gcagagaata attgatcagg tattccttgt tccatgatca
     2221 caccgaataa agacatacat gtcaccattc ctaaaaccat caagcatgaa atagttaaga
     2281 tcatttggac cttgctttct ggatttactg gtagtttaaa ggcaattttt ttcgccagca
     2341 caccgatgat gaagacatcc aaaatgaaag ccaccacgaa tccaggcact agaccaatca
     2401 acaaacttga taaatgaaga tcttgatgca gccataaatt atacgcgctc atccccaaga
     2461 ccatcaaaaa acacatcatt gttgtaaaaa ttattccttc ttttttattt gtaggcaatc
     2521 tgtaccactc ctttaaattt gtcacgaaaa tcatcgtagc acatttaaaa atttctcgta
     2581 agtacttttt ttattttctg cccttttatt tcataaactt catcagccgt acgctcgaca
     2641 aagtaagaat catgagaagt aaacaaaatc gttcccggat atatttgcat tagcttctct
     2701 aaagcttcga tcgttgccat atcaataaaa ttagtcggtt catctaacag caacacatta
     2761 cttggcttag taaaaagcaa agcaatcgtc agacgggtcg cttctccccc acttaatgta
     2821 cataacggtt tcgtcaaagt ttcctgagca aaccctaagt gattcagcaa actacggaca
     2881 agcgattctg aaaactctgt ttgtctcatg acaaaacgaa tgatggattc ttcagatgtc
     2941 atttgataac ccttttgctg atatacttga aagcttactt tcggagagag aaggattcct
     3001 tctccttgtt tgcggatatg ttctaataag gttgtcttac ctgaaccatt ttcaccgaca
     3061 atcgcgattt ttttacctaa agaaaactga aaatcaccat ttaccagtaa tgttctccca
     3121 cttctttcca attggacatt ttgtcccatg atgggatagc ggctgtggag ttcaagagat
     3181 tttggtactg gaaaacggat ttgtttcatc tgctgcggct tggttgtttc tcctattttt
     3241 tggagtcttc tctctaatgt tttcgcattc ttttggatgg ctttttgtac actgtctttt
     3301 tgtttagagg aagacaaccg atccggtctg atttgttgct ttttcttttt actggacact
     3361 ttttccaact tttccgcttg ttttttcttt tcttggatcg atttttccaa tcgttttttc
     3421 tctttcatga tcgactctgc ttctcgtagc tgagtctttt tctccaattc cttttgagtg
     3481 agataggcac tataattccc cgaaaactct cggatttctc cgtcttttac ttcccagatt
     3541 ttcgatgcta gctcatctag aaaatagcga tcatgactaa caaaaaccag cgtaccataa
     3601 taataacgaa gctcttcaat cagtcgatca atactttttc tatctagatg ggttgttggc
     3661 tcgtctagaa gcatcccttg ttcataagaa gaaagaagac gtatcaactc gatctttcgt
     3721 tcttcccctc cgctccattt ccgctctgaa gtttcttcca gtcttaactg gaaatgactg
     3781 gctaattcca aatttaggtc ctttgcttca gcgagatagg ttaattgagg caggtagttg
     3841 aaggtgatct ctgtttggat tttcccatga tcgggaaaaa gttcaccggc tattagtttg
     3901 agcaaagtcg atttaccgac accattttct cctatgatcc ctatacgatc ttgctgatag
     3961 acacgaagag aatcaataga tagttctagc tggttgccaa agctgacttg tagatttgtt
     4021 atatttactg ctaaattttc catatgtttt acactcctat ttcatgtaaa acaacaatta
     4081 tcgatactaa aaaagagcag aaaaatctgt ttgcaaaaaa actgcatcac atcttttcct
     4141 actctgaacg aaataactat gactaaatca ccaaatctgt catagctttc acctattcta
     4201 ctgtcgttcg aaaaaatgga catactccat ccatgaaatt gttgtttata catgtctttt
     4261 gaatttattt agttgttatt caaaagttcg aaacgtaatt tcatcgatgc agtcattttt
     4321 ccgacctcct tttttattag gttaccacac acgattcaaa aaaagcaata gctactgaat
     4381 agtaactgaa aaccttttat tcgaacgtag tgatcttttc tggtgctaaa cgaacagact
     4441 cgtaaccttc ttctaccgct tttcctattg ataaaataat aactggaaca taacggtctt
     4501 tatccaaacc aaatgcctct gccaactgat ctgcttcgac tccaccaatt ggatttgttt
     4561 catagccatg atcacgcgca actaacatga attgcatagc cgctaagcta gaatcgactt
     4621 tgactacatc gttcatttct tctcttgaaa aactcttgta ataaggaatg atcgcagcta
     4681 attgttgatc tctgacttct tttggcatct tccctgattc gtaagcttgg ttatagattt
     4741 cttcgccata ttcgtaacat tgcatatcgc caaaaatcat gaccattgca gaagaagtat
     4801 cattttgtct cgtattgaaa cggatcaaag gacgcaagat ttcttttgct tcctcgcttt
     4861 cagcgaccac aaagcgccat ggttgcatat tgacagaaga aggtgcagtc gtcgcttctt
     4921 tgatcatttc cagcatttct tcgtgtggga ttttgtatgt ttcatcatat acgcgaacgg
     4981 atcttctacc agtcataatt gttgaaaaat catttttttg ttccattatt attaacctct
     5041 ttcgtttctg ttgttatatt gcaaagttgg gtattcaatt tatctaaaag tgttagaaat
     5101 tgtttcattt ctacatcgct gaaagccggg gatagcacgg aacctgtatc tttatggtcc
     5161 atttcacaat gctcgatttt cttctgggct ttttctgtta gcgctacata cacttcccgg
     5221 ttgttctgag gatttctctg acgcgaaaca tagccatttg cttccaatac cttcagatga
     5281 cgagtaactg ctccttgatc aatctgcaac ttttcttgca aactgctttg tagcaatgga
     5341 ttttcttctt tcagtctcat catgatctcg tatctagtaa gacttatacc gatattttct
     5401 tcaaagatct ggacgatttt ttgatcggct aatttgattt gatataaaag gtgactaatc
     5461 tcttctaaag acataatttc ctcctttcta ataattgact cgtcaacgat tgacttgtca
     5521 ataatagaat aaaaaaagaa aaaagtcaaa gaatcagctg tgtaataaaa aaaacgctct
     5581 caatagaaaa gtatagagaa aagaaatttt ttgtagaatg aacggaaaaa atgataaaga
     5641 aagcacaacg ctaaaaccaa gattattgat tcttatcaaa ctatagaaga tagctcttct
     5701 gcagtagaaa attttacacc gccaaaaatt tccgaaatcg ccttttgcaa gaatcccgtc
     5761 gaatattaga aattggatca gtatgcttaa acagtaataa aaaagttatg acaagatgtt
     5821 gtcacaacct tttttgagta aacggtgttc aaaaacttgc atctgcggta ataagttcaa
     5881 ccaaacaaaa aacatgaaaa tctgtttttg tttggctgtt cttactactt gatgcagggc
     5941 agctttttca ctacctcttt ttaataacca taaaatccta ttccttcata tctccagccc
     6001 atcggtgtta gccaatctct ttccttagca ctcaaggtat agtgatgggt accagttttt
     6061 tcatttggat taaatagtcg ataaattggc ttggaaccac cagaataaaa acttagacct
     6121 tcataacgcc aaccgatttt tgttaaagag ttgatctcag attgtgccat tgtgtaatga
     6181 tggtctccac tgtaaggatt gtataaacgg tagacaggtt gtccgctgtt tggtgcttgc
     6241 caagcaatcc cttcatattc ccagcctaca gttggcagat aatttttttc tccggcattc
     6301 aatgtatata aatgttctcc tgtatgacgg ttatacagac gatacatcgg agaagttgaa
     6361 gttggtgctg tatcatactg tgtcagatta taggtttcga ttacattgtt caatgtagaa
     6421 ccataattag gcgcagtggc ataacgacct gttagccaag ccgtagcatc tttgtaagag
     6481 ttcgtattgc ttttccatgc accggaatag tagtaaacgc ctggctgaaa agaagtcgtc
     6541 ttcaataccg ttacgttatc ttgcaatgat tctttgtacg aaggatattt tctaaaagcg
     6601 gcattcaccg taatccattg cccattcaca tattccgaag taggcatcgt aacagattgg
     6661 ccattatagc ttcctttaat cccaaataga ttgtaattag gggcagaagc caaagtactg
     6721 ttcccccagc cactttcaac gatggcttga gcaatcatga ctgatgcata taagtcattg
     6781 gcacttgcca aactttgtgc agttgaggca atactatcaa tgaacgcttg ttgagaatta
     6841 gcagatgagc gagcataaaa agcatagcca gtatagtttt cgaattcaga caaatctgct
     6901 tgatgggtat gtgtcaatgt ttgcccatct gtcaattggt tcgtgatttc ttctgcattc
     6961 tctggattgt tctgagcttc tgctgatgta ctgtcttcgg tttgtgtttg ttctgttgtt
     7021 tcagttgttg gttcttcggt tgaaattgta ttttctgaga cagtagctga ctgcaaagta
     7081 ctctctgtat cgttttcaat tcctgtttct gaagaactcg atgtctgagt tgcgacagtt
     7141 tctgtcgatt cttcagctag cactgttgtg ttggcaactg ctagatttcc taaaagaata
     7201 acgctaaata ataaattctt tgctttcatc ttttttctcc tttgaattat gaaacttttc
     7261 ctaaataaca gtgtaactaa aaaagtaaaa gcaagtcaat gtccatattt aaataacatt
     7321 tgtttctttt tgataaattt gctttttcta cataaaaaga cgtaaatgaa gaatattctt
     7381 ctccattcac gccttaaatt gatggtcgtt tgaataacta tttaacaagt aattctcttt
     7441 ggatattatc cgttatggat tatacttcct gtgtcgtcgg acggataatc atgttactga
     7501 cagacatccg gtctggcgtt tctatcgcaa atgctacagc agaagctata tcttcggagg
     7561 tcaatcccca ttctttttgc gcttcatgaa gttcaagagc agcctttttg tcgctgatgg
     7621 tttgatataa ttcagtttga acagctcctg gagagatgat cgtagatttg atgttatttt
     7681 gccgttgctc ttgacgtaat ccttccatga ttgcacggac agcaaatttt gttccgcaat
     7741 aaacggcgga atcaggataa acaacatgtc ccgccacaga atcagttgaa atgatatgcc
     7801 cagatttttg tttttccatg attggaagta cggcggaaat tccatttaac acacccatga
     7861 tgttgatatc aagcatattt tgccattcat cacggtgacc ttcaactaat ggagcggttg
     7921 gcatgattcc tgcattattg tacaatacat cgattcgacc gaacttttcc atcgctaaat
     7981 cgataactgc ttggacttgt gcaaaatctc ttacatctgc tgtttgaata tatagctcag
     8041 cttctggtaa agattctttt attgctttta ggcgatcttc tcggcgtgca gctataacta
     8101 gtttagcccc tttttctgct aatagcttcg ttgttgcttc accgattccg cttgaagcgc
     8161 ccatgatgac aatcactttt tctgataaat cattcattct attctcctcc tgttttgaaa
     8221 aatctcttgc ttatactcac tatctcttat ttcatcttac tgttcaaata atccgttcga
     8281 caggtttgac gattttggca gggattcctg caacgatggt attgtctggg acatctttcg
     8341 taacagttgc attcgctgca acaatggcat tctcgccaat cgttacgcct ggcagaatag
     8401 ttgctcctgc tccgatccaa gcatttttct tgatgtggat tggctttact aacaagcctc
     8461 ttcgttcttt tggatcggtt agatggttca ccgtgatgag gttgacacga ggaccaatca
     8521 atactgaatc ttctaaacag atgccaccta agtcaacgaa catcacttga cgattgataa
     8581 agacattttt ccctatacta atatgtttgc cgaaatctgt ataaaaaggc agcagaacag
     8641 tcaccgtatc atctactttg tcactaatga tattttctag ccgtttgcgg atatctgctg
     8701 gttcatggta cccagtattc agcgctgcta aaggctcttc gttttcagct tggatctgat
     8761 ggatcacttc aaagagcgga tccgttactc gaatctcttt attgacgatt tgtttttcga
     8821 tgaggcttgt cattttgctc cctcctttta tccttacttt ataacggacg gcttatcatg
     8881 tctaatactt ataaaacata cttaactatt ccttttaact atacttagtg gtatgctttt
     8941 ttaaaaacag gagggaaaaa atggatattc gtatactgac gtatttttta gcagtagcta
     9001 gagaaaaaaa tatcagccga gcagcaaaat ctctgcatat cacgcaacct actctctcaa
     9061 aacaactgaa agatttagaa gaagaacttg gtgtgacact tttcactcgg ggctcccgag
     9121 agatacagtt gacggattct ggtcgatatc tttattcaaa aggaaaagaa atcttgtcgt
     9181 tggtagaaaa aacggcgaac aatttaacaa atgacgcaat catctctgga gaaatctaca
     9241 ttggcggagg cgaaactaaa gcaatctctt tcatttctga tagccttcat tcgttgatca
     9301 aggcgcatcc tgatatccag tttcatttat atagcgggaa tgcagatgat atcatagaca
     9361 aactggatag cggattactt gattttggac tcgtaatcga accgacaaac aaacaaaaat
     9421 accagtcatt tcgactgcca gcccaagatc gttggggact tttgatacat cgaaatcatc
     9481 ctttagcaaa gcaaaccgtc atccatccgc aggaactgaa aactgttcct ttgatcattt
     9541 cccggcaaac gtcagtggac agtcaactag ctgaatggct aggtttcagc atagatcagt
     9601 tatcgatcgt cggaacatat aacttattgt acaatgcttc tttgatggtc gataacggga
     9661 cttttggtgc attagctcta gatgggatca tcaatactta tgggacggaa aaaatattca
     9721 tcccactcga tccgccatta caagcttcac tgaatctcat ttggaaaaaa gaccagcctc
     9781 tttctcctgc tgctcgtaaa tttttagatg tcctaacgga gaaatacagt taagtagagt
     9841 ttttttcctt cgctttcagc tttttaacaa cgaataagat aagcaaaaga tccaacgatt
     9901 aaataacata agtttcttaa tttatttctt ccttttattt ctgataattc cagtaaatta
     9961 ctataattat aaaaaaagaa ttgacaaaac ataactgtct atataaaatt gattacgtta
    10021 acaataattc gtttcatgtg actagatcat actaggcatg aaaaatctct gaggaacatg
    10081 gtttccctag gaggtttttc gtgtctattt ttgtttggcc gcaatcaact ggtctagcaa
    10141 acgtgaaaac caaatcttca aaaagggtgc gcgcatgaaa atcaaaaaga tctttaatca
    10201 aaatgcagta ttggtagatg acggtggaca ggaaaaagta gctattggaa aagggattgg
    10261 atttgacaga aaaagaaatg atttgatttt tgatcgtgat gtcgaacgga tatttgtcat
    10321 ggaaccagaa ggtcaaatca agttgcaaaa tttacttaat cagattgatg aacgcttttt
    10381 atttgcagca gaaacgatca ttgatcatgc ggaaactgtt ttgatggaaa agttgaatga
    10441 acatgtattg atcgctttga ccgaccacat tgctttttct gcggagaaca ttaataacgg
    10501 tatcgtcatc cgcaacaaac ttttaagaga aatcgaagtg ctttacagtg atgaattcag
    10561 tattgctcaa tgggcagtag agtatctgac aaaagagctt gggattccat atacttatga
    10621 cgaagcagga tatatcgcaa tccatattca cagcggacga agcggtcgga acaataacca
    10681 tcgcagtatc cgtgaagtga cgattgtatc tgacatcatc catttagtgg aatcagaatt
    10741 ggaaacagat atccattcag aaccattttc actgaattat tcaagactgg tgaatcattt
    10801 acgactgctt ctacaacgaa cccatgcgca acaatatgct gttttagaca cggaaatcgt
    10861 agaaatggtc aaacgaaaat acccagaaag ctataagatt tctaaaaaaa tccgtgtgtt
    10921 gctgaccaaa gaataccagc tcgcgatcac gaaagaagaa ctgggttact tggccatcca
    10981 tatcgagcgt ttaagaagcg caatcgtaca aacaaatgtt aacaatcatg aggaggaaaa
    11041 aaattgaaag catatctaca acgaatggga cgttcccttc aacttccagt tgcggtctta
    11101 cctgctgctg ctttactagt agggatcgga aactggtggg catcttatag taacgacatt
    11161 gtcgctcatt ttttacaagc tggcggtaac gcagttttag gtcaattacc tttgctgttt
    11221 gccgttgggt tagcactagg gatgtcagtg gacaaatcag gtgctgctgc cttggcaggt
    11281 ttggtcgcat ttgaagttcc agtaaatgtt ttaaaaactg attcagtagc tactttattg
    11341 aatatcaaac cagaatcagt tgatccatct tttgctcaga tcagtaacgt atttattggt
    11401 attattgccg gattgattgc ggcagctctt tataatcgtt tccacgaagc aaaattaccg
    11461 atggctttat ctttctttag cggcaagcgt ctagtgccaa tcttggctgc ctttgtcatg
    11521 ttgctgatca gtgcagtgct actgctcgta tggcctccgg tttactctgc tttagtttct
    11581 tttgctaaat tcattttgag tttaggctgg ggtggtgcag gtctttatgg cttcttcaac
    11641 cgtttactga tccctacagg attgcatcaa gcaatgaact ccgtgttctg gtttgacgta
    11701 gcaggaatca atgatattgg taaatttttg gcttctgaag gaacaaaagg cgtaacagga
    11761 atgtatcaag ctggattttt cccaatcatg atgttcgggc ttccagcagg agcatatgct
    11821 atttacagaa atgcacgtcc agaaaacaaa gcaaaaacag cttccttgat gctagcagca
    11881 gcttttgctt cattctttac tggtgtgaca gaaccacttg aattttcatt tatgttcgtt
    11941 gcttggccat tatatgtctt gcatgcaatt ttcactggga tttctttagc agtgagtgca
    12001 ttcttccatt ggacagcagg atttgccttt agtgccggat ttgtcgatta cttcctatct
    12061 ttgaaaaatc cgattgcgaa tcagccattg atgttgatcg tccaaggatt agtaacagca
    12121 gtgatttact actttggctt taactttgct atcaaaaaat tccatctgat gactcctggc
    12181 cgcgaggaag cagatctttc agatgacgat actgcaacga ctaattcaga caataaatat
    12241 gcggcacaag caagcaaaat ctacgctgca ttaggcggag ccgacaatgt aacttcgatc
    12301 gataactgta ctacacgcct tcgtttgcaa gtcaaagata caggcctgat cgatcaaaat
    12361 aaaatcaaag ccactggcgt acctggtatg aagatcatcg acggaaaaaa tgcgcaagtc
    12421 atcgtaggta cagaagtaca attcgttgca gatgagatgg caaaactaca tggtggtgct
    12481 gcagcacgac ctgcacaaac aaacaccgtg gttaaaacag aaacatttgc cggtgaaacg
    12541 atcgaacaag atatttacgc tatcgcaaat gggaaactga ttccaatcac tgaagtttca
    12601 gatgatgtat tcgcggaaaa aatgatgggt gacggctatg ctgtattacc agaaaatgga
    12661 gaaatcttct ctccaatcgc tggtacgatc acaaacattt tcccaacgaa acatgctgtc
    12721 ggaatccaaa cagatgctgg tatcgaagtc ttgcttcata tgggcatcaa cactgttgac
    12781 ttaaaaggcg aaccattcac tttatatgta gaagaaggtc aaaaagtcgc aagaggtcaa
    12841 ttgattgctt tagttgatct tgccgctatt caatctgcag gcaaaaacac ggatatggtc
    12901 gttgtattca caaatggcga caaagtccaa agcttagaaa tcgaacccgc acgtgatgta
    12961 aaagcaaatg ataaaatcgg ctctgtttcc aacaaagcct gagccatcgt cttccccaga
    13021 cttttttatc gataaacaaa caggagctga gacaaaaatc ttgtctcagc tcctttttcc
    13081 gaataaaaac ggcgttctcc tgccaactcc gcggtaataa gtccagctaa acgaaacata
    13141 tgaagagcta ttttttattt gactcttctt attacttgat gcagaacagc tttttcacaa
    13201 aatttttctt catactcaaa actaatcggc tttttcacaa cctctttata cattattcct
    13261 gatccaatat ttcttttaat gctgcttcaa gagaagttaa tggttttccc aatacttttt
    13321 ctaaatcatc agaggaaata gctaactgat cctttttaat atcatgttgg atcgctaaaa
    13381 acatgtcagc tgcttcttga gggaatccgg cttcttttag attttcgaca aacgctgcat
    13441 cacttgcttc aataatttct aactctttac ctgtcgcacg ctctaatgcc ttggctaatt
    13501 cttcatagtc agttagattg ccggataatt ctaagatttc tggagagtca ctttctacta
    13561 gtacttttgc tgcagcttct gcatattcac gtttcaatgc ccaacctgtt tttccatttc
    13621 ctgcagcata aacgaattga ccagttttta aagcctgccc aatgataggt aattcattct
    13681 ctacatacca attattccgt aaaaatgtat gggaaatacc tgaatcctta atcatttttt
    13741 cagtgaattg gtgatctggc gctaatacac tgatcgagtg atcggcatct gcaaaacttg
    13801 tataagcgat ataagatacc ccagctgctt gtgctgcctt cactacattc ttatgttcgg
    13861 cttgacgatt tcctggaacg ccagagacaa aaagcaatcg atctattcct ttcaacgctt
    13921 ctttcattga gtctaaatca tcataatcac caatacgtat attaaatcca gcttctttca
    13981 gtgcttctcc tttttcttca ctacgtacta gtacatagat ttcattttgt ggaaccatct
    14041 tttttaagaa ttccagcgca taaccaccaa aacctccagt tgctcctgtt actaaataat
    14101 gcatatttgc cactccctat tctttttatt tgttaagatt tacagctgta catttataaa
    14161 ttacaccttt atcataaaga gtgtggtaag ataagtcaag caaaaaaaat gaaaggatga
    14221 caactgatga agtattctct gcaatttagt gatgcaatcc atgtacttgc ctatattgaa
    14281 atgtttcaag atacccgatc actttctagt gagatgattg ccagtagtat cgaaacaaat
    14341 gcagcaaatg tacgtaaaat catgagtcag ctcaaaaaat ccggtttgat ctttacaaaa
    14401 accggaaaac cgcagccttc ccttgccaaa agtccagatc agatttcttt actagatgtc
    14461 tatcgcagca tcgaaggtaa tacacagctt atccaagtcg atccaaaaac aaatccaaat
    14521 tgcgtcgttg gtgcgaatat ccaagaagct ttagaagaaa gctacgctcg gctgcagaaa
    14581 aaggcagaag aagaaatggc taagatcaca cttgatagtc tgatacataa aatagccgtt
    14641 ttggaaaaag aaaaaagacc agaaaacaca ggcctcgtag agagattttt ataattctct
    14701 ctactgtgcc tgcatttttc tgatcggaat cgtctacata aattctttta ttctccgggg
    14761 gacaaaagcc ttgtcatgcc cctttttcct ctctaatgct caggtcaaag cgctgaagtc
    14821 atgacgtctt gataaacggt gttcaagtag ctgaccctcg gcattagttc tgaaaaatgc
    14881 aaaatatgga aagctatttc ccatttttcc tctctaatgc tcaggtcaaa gcgctacttt
    14941 cacgacctct atattatcat ggtttattga ctaccggtat ccagatttct cccatatatt
    15001 tcccgttggt aactcccatt tcgactacag catttggacc cccaacatag gcgtaatctt
    15061 ctacttctct taaaacatgc ccaaaggccg tattcgtcaa atcatttctt aattcttcag
    15121 gcgattctgc taaagcgctt acaacaagat acgttccttt tgggaatggg atgattcgcg
    15181 tagtgtttgg aacatcctga ctcgtttgaa caccgacata gtacatcatt ttcccgttat
    15241 agggttcgtt gactgtaaag aaataatgat tttcagcagc ttgtttcaat gcatctattg
    15301 ttccattacc gataactttt tgctcaaatg cttgtttctc tgcagccaaa ccgacaaaat
    15361 ccgtattgct actcttcaat tccacaccaa tacccgtcac cgtaaaatct ggtttttctt
    15421 cgatcctata ctttgccatt tctcccaccc tttctattat attaagttca tcttacataa
    15481 aattaaaggg aaatgacacg attacgctct tttttctagg gatattttta ttttttaact
    15541 atttttttgc tttcactgca atccaaatct cactgtaaac attactgaaa tcctctcccc
    15601 attttgtaaa agagatctcg ggagcttcga ctaacccata atctgaagaa ggaagccatt
    15661 ctgcatagat tttcccccaa gtatcttgta aagtttgggg aaatggccct ttattaggaa
    15721 aaatggccca agtgtgttct tctatagcaa gcatttctaa atcagcgtac ggattttctt
    15781 ttgtcgtagc aaagccaatc atgtgcatca aactgccctt ttcttccaag cggtctccat
    15841 caaatccata agaaacgttg attacttgat ttggatataa atctcctaac ttatgcatct
    15901 cttccctttg agtctccgtg atcgtctgcg ctaacttttg tatttcttga ttgactcctt
    15961 caaatttgac aggaactttt ttcgccacac ctgccacata aaactgttct ttcttttcga
    16021 tacgaaattc catcgatttt cctcctctga catcaataaa aaatgtcaag cgtggaaaag
    16081 atttttgtat gccgtatctg ctgatttctg aaggcagata tcctgaccaa tcacgaaaag
    16141 ctcttgaaaa accttcgact gtttcatatc catatctaaa cgccgtttct gtcactcttg
    16201 atccatctag aagatcgcga ttagccaaag ccaatctacg gtttttgata tagtccatta
    16261 gcgacatccc tgcaataaac gtaaagatgc gttttaattg atattcagag attcctgtat
    16321 tttcggctat tattttatag gaaagtcctt ctgtcaaatg ttcttcgatg taatcgatca
    16381 attggttcag atctttaagc atatttatct tcctccttga ttgccttttt atcatattat
    16441 caaagaaagt caattacttg atgaatcagg aaccaattta gtcagatgta gaaaatgttg
    16501 tatggatcta aagaaaattc tcaagcagcg tttcgtaacg gataattggt attatctgcc
    16561 tatctatgtt ttacctttag aaaaataaat tttggggaag acagattcta agtaaacaaa
    16621 gcggtaaaaa tatcttttat tcccttagtt aatccgctta ctacctactg tacaaagcaa
    16681 attgttgttc aaactgctga tcagaacgct gcttggattt ttcttt
//
LOCUS       DADGHT010000063        16278 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.063, whole genome shotgun sequence.
ACCESSION   DADGHT010000063 DADGHT010000000
VERSION     DADGHT010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.063"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(85..582)
                     /locus_tag="JX887_001873"
     CDS             complement(85..582)
                     /locus_tag="JX887_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAX1257854.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(712..1422)
                     /gene="budA"
                     /locus_tag="JX887_001874"
     CDS             complement(712..1422)
                     /gene="budA"
                     /locus_tag="JX887_001874"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAX1257855.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(1435..3099)
                     /gene="alsS"
                     /locus_tag="JX887_001875"
     CDS             complement(1435..3099)
                     /gene="alsS"
                     /locus_tag="JX887_001875"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAX1257856.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(3304..3966)
                     /locus_tag="JX887_001876"
     CDS             complement(3304..3966)
                     /locus_tag="JX887_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAX1257857.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(3976..4791)
                     /locus_tag="JX887_001877"
     CDS             complement(3976..4791)
                     /locus_tag="JX887_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1257858.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(5053..5496)
                     /locus_tag="JX887_001878"
     CDS             complement(5053..5496)
                     /locus_tag="JX887_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAX1257859.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(5630..5968)
                     /locus_tag="JX887_001879"
     CDS             complement(5630..5968)
                     /locus_tag="JX887_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1257860.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(5956..6333)
                     /locus_tag="JX887_001880"
     CDS             complement(5956..6333)
                     /locus_tag="JX887_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAX1257861.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            6557..7750
                     /locus_tag="JX887_001881"
     CDS             6557..7750
                     /locus_tag="JX887_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1257862.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(7916..8338)
                     /locus_tag="JX887_001882"
     CDS             complement(7916..8338)
                     /locus_tag="JX887_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1257863.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            8928..9383
                     /locus_tag="JX887_001883"
     CDS             8928..9383
                     /locus_tag="JX887_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257864.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            complement(9545..10717)
                     /locus_tag="JX887_001884"
     CDS             complement(9545..10717)
                     /locus_tag="JX887_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAX1257865.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(10923..12352)
                     /locus_tag="JX887_001885"
                     /pseudo
     CDS             complement(10923..12352)
                     /locus_tag="JX887_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            complement(12349..13851)
                     /locus_tag="JX887_001886"
                     /pseudo
     CDS             complement(12349..13851)
                     /locus_tag="JX887_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345213.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            complement(13848..16175)
                     /locus_tag="JX887_001887"
     CDS             complement(13848..16175)
                     /locus_tag="JX887_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAX1257866.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         4643 a         3251 c         2877 g         5507 t
ORIGIN      
        1 aaaaaccgaa aaacagaaat gcccactgtc tttccggctc tttttattct tgatttctct
       61 tcttttttgt ttcaatagac gattttagtt attaataaat gaaaaagcat ttatattaaa
      121 atttgctaat aaaagatcta catatttttc tagaaatgct tgatcgattt catcataccc
      181 tttcgttact ccgcaatcga tatctaaaac accgattaaa ttaccttctt ttaccattgg
      241 cactacgatt tctgattgtg cggctgaatc gcaggaaatg taatttgcat gggttttgac
      301 atcatcaacg atcaatgttt cttgtttttc agctgattct ccacaaactc cttttcccat
      361 cttgatacgt gtgcaagaaa ctcgcccttg gaacggtcct aaaatcaatt cattaccatc
      421 gaataaataa tatcctgcaa agacagtctc aggcaaagtc tcattcaaca atgcagatga
      481 atttgctaaa tttgctaacc agttatcttc tgcttctaat aatccttgtt gctgtaataa
      541 taaaatttcg tatgcatctt ttttctgttt ttctgtccac atgataaaaa ccgctccttt
      601 ttgatctatg gagaagatta tagctcagtt tttttgtaaa cgctaggttt tctcctcaaa
      661 aaaacgagat acgtcaggtt aatcaccttg aacgcatctc gctgtctttt tctattctgc
      721 ttgttggatt tctgctgcta aatcagcata atcaatcgtt tcgtgaacaa aagtcggatc
      781 atcaactgga aaatgctgta caagggacga gatgcggcta atctcaactt ttccttcagc
      841 cacttcaaaa tccattacat gtccgccaaa tgtatgtgta tcatcgataa aatgcaggtg
      901 aaatcccgct gcagcaactc cttggaataa ttcaggcgta aagaacccga ctaatgttcc
      961 ttggacattg ctttgttgga attctggttg agactctgaa atttttgcta gtcttctgta
     1021 aggtttttct tgcttcggca tgatacggat gtgcatattt ttgaataatc cagttatctt
     1081 cactgccaaa aataggtttt ccccggcttc tcttactaat atgtcttttt tcaattgttc
     1141 tccatctgca gtttttgaga cagaaaaact agtatctggc gtaaaatctg taattgctgc
     1201 atagggggta agttcacttc catctaattg ggcaactgag ccatctgatc ttccttgata
     1261 agctacgcca tctaaaaaga tgacttcacc atcaagccca tgcaatgttc ccaatcccag
     1321 agttcctttt tctaatatat gagcaatcgt ttctgttcca tccatcaagc cagccatcaa
     1381 agctcctaat gtcccgtgct ggtataagat tttttcagtc atgtcgacac ttccttaata
     1441 gaattgatct ggtaagattg tttctcccaa tttctcatta tcacggtaat caatcggaat
     1501 atcaataatt acgggtcctt ctgtcgcaaa tccttcttct aaagcttttt ctaattcctc
     1561 tacacttgta gctcggattc ctttagcgcc aaaagcttct gcatatttca caaaatcaac
     1621 tggaccaaag tctacacctg acgcccgctg atatttcatt ttttcttgga actctaccat
     1681 attgtagtgt ccatcattcc aaatcaaatg aacgatattc aattttttac gtaccgccgt
     1741 ttctaaatcc tgggcagaga ataaaaatcc cccatcgccg gaaactgata cgatttgtgt
     1801 atttggacgc accaatgcag cagaaatcgc ccatggcaat gcaacaccaa gcgtttgcat
     1861 accattactg aataacaaat gacgaggttc ataacttcta aagtggcgtg ccatccaaat
     1921 ataatgacta cctacatcta cggtaacagt catatcatct gttacttttg actgaagcgt
     1981 gttaataact tctaaaggat gcaagatacc tgcttctcct tttgattgaa caatgtcccg
     2041 ctccgttaat tctgcttgaa gagatgctaa atattctttt gcatcttctg acacttgttg
     2101 aggctctaat gaacctgtca ataaatcaag agtggctgag atatcaccga tcaattctct
     2161 ttcaggctgc ataaaaggat cgatttcagc tggcgcttca tcgatcacaa tgatccgcgc
     2221 atctttttcc gcattccagt ttcttgcttc atattcgatt ggatcatagc caatagcaat
     2281 aactagatca cttcgtttca aaagcatatc tcctggttgg tttctaaata aacccacacg
     2341 accaaagaaa tgcgcttcta attcacgtga gatcactcca gctgcttgga atgtctctac
     2401 aacaggcaat gctgtctttc caactaattg cctgatggct aacgtttctt tttcacttga
     2461 tcctcgcata cctactaata gtaccggtag ttttgcttct ctaatgcgtt cagctaggta
     2521 acggatatca tctgcagaag cagaacctaa tttaggatcg ctcaatggct tgatgacatt
     2581 cccttggaca ggtgcatcca ctacatcttg cgggatactg ataaagctcg cgcctttttt
     2641 tgaactctta gccatacgat aagcattggc aatcacttct gaaattgttt ctggatcttg
     2701 gatttctgca ctgtattttg tgattggctg gaacagtgct gcattatcca tgctttgatg
     2761 ggtcaacttc aatagatcgc ttcgttttac ttgtccggca attgctaaaa ctgggtcacc
     2821 ttctgctgtc gctgttacca aacctgtagc taagttacta gcaccaggac cacttgttgc
     2881 gataactact cctggctctc ctgtaatacg tccgattgct tgtgccataa atgcagcatt
     2941 ttgttcgtga cgagtcacga ttaattcagg accttgatcc tctaattcat taaatacacc
     3001 atcgattttt gcacctggta taccgaatac ataatcaaca tgatgattaa tcaaactttc
     3061 tactacagat ttcgaacctt gtttcatttt ttcgtccatt gaacatcgtc ctttttatgc
     3121 tttattttta attattagtt agaaataatc acaaataatt gatacagttt ctaaacctgt
     3181 ttcattcaaa agtatagcac gttttatttc atttgtttag ccatatgttt caaaaaatga
     3241 aaaagaatga cagtttttac ataaaaactg tcattcttaa ttgaaagttt caatttataa
     3301 agtctacaga tccatagttc tcatcaattt acgattgttg aagtaaatca aaccaaatac
     3361 gatagaagga cctagtagaa tacaccattg gggctttacg aaaaagaaga gaaacaaact
     3421 tgtcaatagt aaaaaatcta gtaaactcac ataccatttt ttcaacgtat agtagaacgc
     3481 tatccgtaga acttgatttg gtttcgacgc tggatttctc acctgaaaat accagtagtt
     3541 gatgctaaag gaaactgata aacaagcaag taaaacaaac aacggaatca accattttcc
     3601 ataagaaaaa cgtataaaaa agaaacaatc aaaaatcatt atcacactaa ctatccaagc
     3661 aaatagccaa taaaaaaatc cctttagcca aaattggcga aacgtcttta tgaacaaacg
     3721 tactggtgaa aaactttttt cttttgctaa ttcttctgtc atacctatca tcacgatgca
     3781 acctggacca ataaaaagta aagaaaaaat aaaggaaaag acattccttc catctatcga
     3841 caaaaggaac gcagctgcta tatacaagat attgacacac caaaaacaaa ggctacttgc
     3901 caatgattga tacaaccaat aaaagaattc catataaaca tttttgtcaa aacgctgctc
     3961 tttcataatc acctcctatt ccttcattcc tgatgaagcg atcccttcta caaaatattt
     4021 ttgcatcgct aaaaatataa aagcaacagg aagaacagaa acaactgagg cagccatgat
     4081 taatgcgtac tctgcatcaa atagcccaat aaacattttc aaccctaact ggattgtttt
     4141 attttccgta gaagacaaat aaatgaatgg ccccatataa tcgttccatg tattaacgaa
     4201 tgtgatgatc gtcaaactgg caatcgccgg ttttgtaaga ggtaaaatga tcttgcgata
     4261 gattccccac tctgataagc catcgatccg cgcactctca cataaagaat ctgggatact
     4321 actgtagtat tgcttcaaca agaacacacc aaaagcattg aacgcttgta atagcaccaa
     4381 cgaccacaac gtatatgtta aacccacttt tctcatcata atgaactgcg ggatcatata
     4441 agactgccaa gggacagcaa tcgtgccgat atatgctaaa aataaaatat cgcgcccttt
     4501 aaaatttagt ttagaaaacc cgtaagcagc aaaactagaa gtaaacaact gaatcaacgt
     4561 gatcacaacg cttaaaaaag ctgtattctt aaaaaatgtc actaaaggaa tacgagacca
     4621 aataaccaga taattctcta aatgccaagt tttagggatc cattgaatcg gaatcgtgaa
     4681 cacttcatta tttgctttga atgaagcaga aaccatccat aaaaaaggaa tgatcgtcaa
     4741 taaagctaat acaatcagca gaatcatacc caaccattga ataaagggca tgttttttga
     4801 acgaattttt gctttttttc tttcatttcg aacacctcca aagttataat cttcatttct
     4861 ttgtaatgat tacaatccag aacaacggtt attatagctg attcatttcc gttcttctta
     4921 tgtttgtaag cgcttattta acaagttatg taaatctctt tatttttttt gatttaaaaa
     4981 tgaaaaaata caaaagcaag actgtcatac gtctcgcttt tgtattgaaa tttcttcgat
     5041 tagagatact tattactgtt caaaagcttc tttgaaacgg tgaatcaatt cattgactac
     5101 aggtgataaa atccgattct ttttccagac tagcatgcag ttcgtttcaa tcattgggtc
     5161 aagcggaacg aatgtcactc gctttgaaag atgacttaca gcaccttcta tgactaaagc
     5221 agcacctacc tgattctcaa ttagcgcaaa tacattgaaa atcaaattgt acgttcctgt
     5281 gatcagcaac tgctcctttt ttatgcctaa ccagtcagca aacattcgct gtatttctgg
     5341 acgctttgag atcaaaagag gtacattcgc aaagtcttct tttgttatca cgtctttttt
     5401 tgctaaaaca gaattttcta aaatgagcaa tccccatttt tcctttcttg gtaacaaaat
     5461 cgtttcgtat ttctctgtat ctactggatc tagcaaaatc gctaaatcta acaggctttt
     5521 ttctagtcac tccgtgatat catcacttgt tccgctgtgg atatgaaatt gaacgctggg
     5581 ataatcacgg atcaactttt ctagtaatag tgccaatgta ttcgaattat cagcttccac
     5641 acagccgatc gtaaatcggc cgctgaataa ttgttttttt ctgttctcga attcttgagt
     5701 ggtttgattc gttaaatcta aaatttcttc tgctcggctt ttttagaaaa taacctgctt
     5761 ctgtcaagat cattttgcgg ttttcgcgta caaacagttc tgttcctagt tcctcttcta
     5821 actccttcag ttgtcggctt aaggttggtt gtgtaagatg tagaacttct gcggcttgag
     5881 agattgttcc ttcttctgca attgtccaaa aatattttag taagcgtaac tccatagcga
     5941 tgctccttga tttttttact tgatacattc cattttattt ctagataaca cacgatcata
     6001 tttcttgatt tttccttgta aacgttccaa acattcttgc atttcagcaa tttttttcgt
     6061 caaaagttca ctttcttcaa tcaaaagctt acgccgctca aatacagttg cttctccttc
     6121 gctagatagg cgaatatatt caatcaaaga ctcgatcgat aatccggcat ttcgcataca
     6181 gatcgtaaag tcgacccatt ttaggtcttc ttctgtataa tcacggattc cgccttttgt
     6241 ccgattaact ggtggaatca acccgattcg ttcataatag cgcaatgtat cggccgaaat
     6301 gcccttttct tcactgactt gtttgatatt catctgatca ctctttctct taatttcttg
     6361 ccactttact tatgtatttt atttattcta caactttaag tgtactccaa gtcaatactc
     6421 atttctatta aaactaagct ggattatcta tatcggttgt ttgtgtatta tttcaaataa
     6481 aaaagtcttg tttttttatt cttttttgga tatactttta acaatttagg gaaattttag
     6541 gaaaaggggt ataaaaatga caacgtatca gcgaaagtta ttattatcga catcggcggg
     6601 aattgcttta gagaatatgg atattatgtt tttagctttt tcattatctt caatgattac
     6661 ttcttttcat attagtggta cgcaagcggg tttcatttca acgatcacta atttggggat
     6721 gctcattgga ggtatttttt ttggcatcat agctgataaa tatggacgtg tgaaagtatt
     6781 ttctcaaacg gtccttctgt tttcgattgc ttctttattg atgtattttg cttcaaacat
     6841 ctacttggtt tatctctttc gctttatcgc aggtgtagga gcgggaggag aatacggggc
     6901 gtgtatgtcc ttgatttccg aaagtttttc aaaaaaacaa attggacgag cttcttcggt
     6961 tgctggtatt ggtgcgcagg tcggtgcggc tttggctgcg attttagctg ctgtgatcat
     7021 tccaacgttt ggttggaaga tgttgtatgt cgtaggtgta ctgccggtgt tgatggtctt
     7081 gttcattcgt cgcggcttga ctgaaccaaa ggaattcaaa tctgtacaat ctgccgaaaa
     7141 gaaaaccaaa cttagcagac tgtttgaatc aaaacatctt gcttggcaaa catgtggcct
     7201 tagtatcatg gtaactgtcc aaattgccgg ctattttggg ttaatgaatt ggctgccttc
     7261 aattatgcaa aatcgattag ggctttcggt ttctgggtct tcattgtgga tggtcagtac
     7321 tattttaggc atgtctttgg ggatgatgac ttttggcata atcatggata aattggggcc
     7381 taaactagcc ttttctttgt ttttaatttg ttcatcctta tctgtctatc tacttgtgtt
     7441 agcccatagc cagtggagtt tggtagcagc cgctgtgata gtcggctact ttatcaatgg
     7501 catgtatggt ggatatggcg cagtgattag tagtttgtat ccaacagaaa tccgcgcgac
     7561 ggcgaataat ttcattatga accttggacg agctgttggt ggtttttctt ctatcgtcat
     7621 cggtttcttg atggatcatt atagtttaac tgccgtaatc ttgtttttga gcggtattta
     7681 cctagtcagt ctgctggtct tgacaactct tactggtgtt acagcattaa gggaaagctt
     7741 gcagcattga tagttgagtc tgtaaatgac aagaaagagg tgtggcaaaa gcttgcatct
     7801 gcggtaataa gaccagccaa atcaaaaaca tgagacactg tttccgtttg gctggtcgta
     7861 ttacttgatg cagggcagct ttttcaactg ctaatttcct tctatctggc ggctactatt
     7921 ctttgacgtc cgtcatttca aagtacttta ctaataactt agcataacga aaaactgtgg
     7981 atacactcgt atattgagcg tctgcataat cttccaaatt tttctcagga tgttgataca
     8041 tgaattcaat caaatgataa ttatatgatt ttctgtagaa atgaagataa ataatgtaga
     8101 ttgggaagtt ctcctgcttt tccatagaaa agcgccgatt attctcattc ttcaaaatga
     8161 ccttatcagg atatttttgg aacaattctt ctaaatctgt tagataattc aagatagact
     8221 tacttgatac cttcaattcg ttttgtagtt cttctattga acaccaacgt tctgtttcaa
     8281 gcagtaaatg aatcatttta attttctttt gagaaacttt tgttaaaaaa gtctgcatat
     8341 tttctcctcc tgtatctact ttactatact acatacaaga aaaaaaacgg atacaaatat
     8401 catattgtca caccgtcaat agtgcataaa cctgttatta tttctctttt tttcctaagt
     8461 attctattga tatgaatcat ttaatcgttt attatataaa tgtcaataat ctaataataa
     8521 aataacgtac atattttatt attgcatact taataacaga actatagcaa aaaatcccgt
     8581 gtatcaaaac gggattagat taagtttcct caatcactat tcataacaca attattataa
     8641 caagtaagta aacaattgaa aaggacattt attgaaaacg gttgtttttt acttaaggag
     8701 gaaatttagt gaaaaaatta gttgcattgt ttttggtcgc aggaagtttg ttgagtgggt
     8761 gtggtgctac tacgtctact actcaaagca caagttcagc tcaggcttcc agcagcagta
     8821 ccacgatctc cgaaagtacg gcagattcat cgaaagaaca agaacaaatt gaaaagaaaa
     8881 aagaagaaga gaaacaaaaa gcggaaaaag ctgcactaga aaaaaaagtg acagaagcgg
     8941 aatctgcttt gtcacaagct gaagcaaatc ctacaaaaga aaactatgca actgcttcag
     9001 cagctatcca agcgctacct gaaaacaaac aagagttgac aagccgtctt gctgcaattg
     9061 attccacaat caaagcaaaa gaagcagaag aagaacggaa aaagcaagaa gaaattgcac
     9121 gacaacaagc agaacaagcg caacaagaag caatcgcaca gcaacaagca gaacaggcgc
     9181 gacagcaagc agcagctgaa caggcctctc agcaggcaca agccgcagct cctgagcaaa
     9241 ataatgaaca aactgtctat gtcacaccga ccggttcaaa ataccataca cataaatgtg
     9301 gaaatggtac gtatacccct gccactttaa gcgaagctca agctcgtggt ttaacccctt
     9361 gctccaaatg ttatggaaac taattcaaaa gttatactat aataataaaa ttcttctgaa
     9421 acataaaaaa atagaagctg gcgttccaga tagtaaacca aaaatagcag tttacacgtc
     9481 catttcgtca gcttctctct tttttcattt agtctgttcc ctctgctttt ttggacatct
     9541 tcattcattc tttctcaatc aaatagtaca cctctttttc ttttcgcagt ttatatcttc
     9601 cttttttcaa tttcattgaa aactgtttcg aatgtttatg ttttacatgg attttaagca
     9661 ggagctcctc atgttgcaag cgatagttcc tgccttttaa atcagaaaat ctcactagtc
     9721 cgtattcatc agaagctttc acaaatggaa ctttttctct agtaatatag tgtttgccgt
     9781 tgagcgtttt tacagaaaag accattcctt cgattggtcg tccgtttgtg ttctttacat
     9841 aaaaagataa aggatagttt cgcttagcga tggccaaaga atctaaataa gcgatgagta
     9901 gccaaactaa gccgattgat ccaagtagta taccgataaa ccaaataaaa aatttccatt
     9961 ttttccattg atcaattcct tggatcgctt tttttgcctc ttttgcttga taaggaatac
    10021 gatgccccgt cacaagcagt cgatgtgtat tgaccatata aggagtacag gtaagcaaag
    10081 tcacgagatc tctgcctttt tggataccca aagaatctac ttcatcaggt aagaccactt
    10141 ggattttttc tacttgatac gccaatgtct ttccattgat ctggatgaaa aactggtctc
    10201 cttttttcaa cttaggcaaa tctgtaaata attttgcttc tgggagtcca cgatgcccag
    10261 aaagaacggc atgggtgttt ttcccgccag tcggataaga actttcttcc aataatgacg
    10321 ttcctttttg caaaaatatt tccgttgtct gatcgaatat aggtaagctg acattgattt
    10381 ttgggatttc gatgactcca agcatatgtt ccataaaaaa ggcattacta ggtaaatctt
    10441 ttaatgcttt tgcatcaact gcttggttga aactgcctat ccctggtgat acgttttgct
    10501 ctgccaactg ttggtttttc tttgtcattt tttcctgctg tttttttatt tcctctgaat
    10561 tcttattcga tgcttgcttt tgataatgga tgatcatttg ctgggcaaga aaatcattca
    10621 gtgaatcttc tacaaaagga taagaaaaga tcccgatccc aacgactaaa atgattgcca
    10681 tgaagatgtc cagtattctt attctgcttt tattcatcat gtccacctat tttctaatat
    10741 gtatatgaag aggttgtgaa atcagcgcct tgacctgagt attcgctcaa caaacggcaa
    10801 aatagttcct cctattttgc cgtttgttga gcgaatacca agagaccgac cacttgtcac
    10861 aacctttctc cccatttgaa tcactatcgt ttatttatcg tatgattttt gtttccaata
    10921 gtttaagctt ctgtttcttg atggcgtttt ttgaagtaga tcactgctcc tccaactaaa
    10981 gcagtaccta ccaagatgaa tacgatgatc cccataccac cagttgaagg caagattcct
    11041 ttaggttggt tatcgatcgt tgtttcatca gaagttgttg gatcatcatc tactgtaaat
    11101 tcagtgtacg cagcttcatt cttaggtaat gcgtagcctt ctggtgcttt tgtttcttga
    11161 aggcagtatg ccccttgttt cagcccttcg attgaaaatt tcccttctga atcagaaatc
    11221 aatttcactt cttcccagtc agaacctgtg acttcatctg accaagcata tgggtattct
    11281 cctgaggcaa gatttgctat ttttttcatt aatttaacag ttggatcttt tgctcttaga
    11341 atagaaaatt ctgcatcggc taatttttct tgcgtgttca catcttgttt gatgaagtgg
    11401 aaatcaccgt agttttggac attttctaca gtaatcgtgt tatccgtagt tgtattttcc
    11461 cgattgacta caccgtttgg attcccaaga ttggcttcat ctgcgccatg gatgataccg
    11521 gttgtttgtt gcaattttcc gttttttact ataaaagtag tttctttttg tggattggtt
    11581 aattgataac catctggtgc ttttgtttca actaaagtat aattgccgtc tattaatcca
    11641 ttgacactga tggatccttc agtatcagtt gtgaatgtca acgctgactc agcaggatca
    11701 tagagagcga caccagtgtt ttcatcaaaa ccggtcacga attgattctc tgaatttttg
    11761 atctggaatt gcgcccctgc taacttatct acccctgaaa agttcccagc tttctggatt
    11821 ttgatattgc tttctttgat gacattttta gcatataggt gaatcgtgtc taaaggtttg
    11881 tcagggtctg atgaattcgg gttataaaag ggtaagctta acacgatatt tggcgacgtt
    11941 tcgacaccgg gctttggtgt ttctacaaag acgtatacag catctttccc atcagattta
    12001 cctggaagag tcaggttagc taatccttca ccagaagtcg ttacacttgc gaagggtgta
    12061 gcgtctgctg gaactgctgt gtctttactt ggatagtacg tagcagtgat gtcatatacg
    12121 ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg tcaattccgt tccgttgttt
    12181 atttgatttt ctggtgctga agtgaatttc aatttatgca aattaaccgt aacattttct
    12241 ggtgtaggtg atacggccta gaaacctctg cagttcctag gccgagaacg aaaggaagca
    12301 gcatgatagc agttcctaaa aacgtccata tttttgtttt gatgtttttc attttatttc
    12361 cctcctattg tttccttttt gttgtttttt ataaaaccaa gctgtccctg ttgaaaggac
    12421 tagcaacaac cctaaaattg agaaacctcc aagcatctct tcgcttgttt ttggaaagct
    12481 tcctccattt ttttcatttg atggaccatt tgtctgcatc tgaactggcg tttttccatt
    12541 attcgtcgga tttgcttttg gttcgttgat gatttccaat ggtataggat gaagcggatc
    12601 ataactgcct ttttcaactt caaagagaat ggttgattga ctcaatatat atcctttagg
    12661 cggtttaatc tccactagtt cgtaacttcc aaaagacaat ccatggacag aaaatgttcc
    12721 atctttactg gaagtaaaaa tcgttgctct tgaatcatct ttggctaccc aatgatttat
    12781 cccgttttct tgcgctaagt attggtcatt ttttttgact agaaattgag catctgctag
    12841 tttttgtttc gtttgccgat ccactttgac aaattgtttg cctcctgttt ggatggcaag
    12901 atgtgtttct actgtttgat tgtcagtcgt caaacgtaca tcgttatcaa atgtcgtttt
    12961 ttcactgttt tctttcaatg tcatttggta acggatcgtt aattttttcc cagcaaacga
    13021 actaagatct tttccagaat ctgataagac aaaaccatgt tttgtttttt gtgtgtgaaa
    13081 tgtatgaatc ttgtctccac caatcaaaaa atcgatcgtt tctggttcta gccataactg
    13141 aggatcagct gtatctttga tcgtataggt tcctatctcg ttgatgttct caggaattgt
    13201 tacggtgatg agataaggaa ctttatcccc atctgcaaaa tctgtctgct tattctctac
    13261 tgtttttgtt aatgtgagtg cagcaggtat tttttgttcg ctctttggat acaagtggat
    13321 ggtcgtcaat ttatgattag atgaatctgt cacaggaagc acaacgacaa atggtgctga
    13381 tttttctttt acttaatctg aagtctttat ttccgcaaat cggtaaacag cgtcacgacc
    13441 ttgctcatct ttgtccgatg cactaaaaga agcaatgccc tcttcctcgt ctactgtttt
    13501 tgtcacattt tctgccagta ttttttcact atcacttttt tgtgctagtt ttctttgtgc
    13561 gtcttccaca ctacttcctt ctgaccgcag cttgtaaaat tcatccgaga catcatatat
    13621 agcgaaagta acgccgttca acccttttac tccttgaaag ttatccggga tatttattcc
    13681 gtcgttttga ctgatacttg gcatcttatc gctttcgaac attcgattat gcaaagtaaa
    13741 tgtaataggt gattctctag ctgacacagt cggagaacct ataaaaaaga ccagtaggat
    13801 aaaaaagaga acagcaaata tatccacacg tacatttttt gtttttttca tcgctgttca
    13861 cctgcttttt tcttacgatg gataaaataa aagaagccag aaaaaataaa gatcagtcct
    13921 aaaaagacaa agggcagtag acctatccca cctgtcgaag gaagcaagag agtcggattg
    13981 atcgtcaact tagcggtatc tgttgcgata atcgtataat tattgtttac acttccttcg
    14041 cctaaactaa tcgttactat ttgtgatcca atatctgtcc ggctgttaac tgttagggta
    14101 taatccaatg attcgcctaa gacaacaccg gtaacgtgga gatttccaac cgaaatcgag
    14161 tgactttggg catcataatt aaaggcagcg tcatcgacag taatcactgc gttagcttta
    14221 tagatggtat aagttcctga tgtgttggct atatcagtaa atgacaactt gggatttgct
    14281 gctttgactt tgtctattcc gctattcgtt agtttaattg tatagctgcc agcattaacc
    14341 atattttttg ctgattgtgc atctgctgtg taatccatac tgctaagtgc cacttgtact
    14401 ggagtaagcg aactagtgac accctctgct agcttgacat ggattgacgg gacacctgct
    14461 tttccatcat atgtcttact gccactgagc tctaccgcac cgctgatttg cttaatcgta
    14521 tagacatcag atgtctgcac gatagtaaat aaatagtttg ttctggcagc tagtttagct
    14581 agtccgcttt ttgtcaattg ccaagacgta taggttccaa tttcagtagg cgcagttact
    14641 tcaactccct tttcattcat cgctttgaaa tcagttggat tccatgtgat ttgatcaata
    14701 ctgagatcat tgtttaaaag ggatgttgat tctgttttat cattaaaggc atatttaacg
    14761 atcggtacaa cagaaagacc atcatagtac ttactgccat ttgcattgat tgatactgtt
    14821 gcatttgtct tataatatag gatgacttca gaaatctgtt ttccatttgc gtcctttacg
    14881 attacatttc catttgtatc taaactagct aaaacactca ttgctgattg gttctttgtt
    14941 tctgtcgctg aaacagctgt aaaggtatat ccgttgatag taggcgtatt agtcgtcagg
    15001 tcttgtgcag cacttccgta agtaagattc attattttag aaggagcaat catctgtcca
    15061 aaatagtctt gatacttaat agtgattggt gtttgtttgc ctgtataggt caccgtatcg
    15121 acgttacttt ctagggctgt gaaagaaccg tttgtttgtg caaaagaata gcccgttact
    15181 gctgttggag tgataaccac tttgtcaccc acatggattc cagataatgt agtcccgtac
    15241 gttccgattt ttgctgctcc accattgact gtataagaaa aagttcctgt ccgattcgca
    15301 ttgacctgaa ccgttgctgc ttgataggtt ggaaaatttg aaacatttcc cttaccatca
    15361 acgatctgcc catttttgat cgagtacccc gtgaatggaa tatcatttgc taactgtata
    15421 ccgattgaaa aagtactcat acctcctccg gcaggaagcc ctccccatgt tgagggtgta
    15481 aaagaataac ttttatccgc attgggtgta actgaatcga tcgtatttcc agcggtagcc
    15541 acccccatat agatactttt tgggaatgtg atagtagtac catttactgt ggagccaata
    15601 aacagattat ggatatctgg acggttatca ataaaagcga ttgctttggt tacgccttgt
    15661 aacgcagttt tatccgcact catcgatccg ttaaccgcaa caatgactcc atctttggca
    15721 tatatcactg tatatccatc tggtatggta tgtccgttga aattcgcagt ggccgcaaca
    15781 gtactaaatg tctggcttct acctgtttct gaataagctt tctcccctgc tgcttttgct
    15841 gctgtgattt ctttttctgt cggatcaatc agttgagtcg aggatgtggt tgaggttgtc
    15901 tcgttgttgc tagactgatt ggtgctttct atggactgta tttcagaata gggtggacta
    15961 tttgtctcct ctgtcgtttg gttagcaaaa tttgacgttt ctgtataaac gtttacataa
    16021 atacttgata agctccctaa gaaagtaaaa atcaagatga tcgaaatcat aatgggatgt
    16081 aagtattttc ttttagatac agctttgagt ctagaaacaa aatgtttttg acatatacgt
    16141 tggattttat tttgagtttt cttaatcatt ttcatccctc ctctcaataa aaaatcatca
    16201 aataatcctt tacacgttat tctaaattta atttttatta ttttattgat gtatagaaag
    16261 tttggggctt tttttctc
//
LOCUS       DADGHT010000064        15860 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.064, whole genome shotgun sequence.
ACCESSION   DADGHT010000064 DADGHT010000000
VERSION     DADGHT010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.064"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(12..482)
                     /locus_tag="JX887_001888"
     CDS             complement(12..482)
                     /locus_tag="JX887_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAX1257867.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="JX887_001889"
     CDS             complement(641..1099)
                     /locus_tag="JX887_001889"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAX1257868.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="JX887_001890"
     CDS             complement(1270..2415)
                     /locus_tag="JX887_001890"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAX1257869.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="JX887_001891"
     CDS             complement(2428..3345)
                     /locus_tag="JX887_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAX1257870.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="JX887_001892"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="JX887_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAX1257871.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            4822..6081
                     /gene="lysA"
                     /locus_tag="JX887_001893"
     CDS             4822..6081
                     /gene="lysA"
                     /locus_tag="JX887_001893"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAX1257872.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            6068..6868
                     /gene="dapF"
                     /locus_tag="JX887_001894"
     CDS             6068..6868
                     /gene="dapF"
                     /locus_tag="JX887_001894"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAX1257873.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6871..7752
                     /locus_tag="JX887_001895"
     CDS             6871..7752
                     /locus_tag="JX887_001895"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAX1257874.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7749..8465
                     /locus_tag="JX887_001896"
     CDS             7749..8465
                     /locus_tag="JX887_001896"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAX1257875.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            8471..9166
                     /gene="dapD"
                     /locus_tag="JX887_001897"
     CDS             8471..9166
                     /gene="dapD"
                     /locus_tag="JX887_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAX1257876.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            9182..10183
                     /locus_tag="JX887_001898"
     CDS             9182..10183
                     /locus_tag="JX887_001898"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAX1257877.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            10180..11541
                     /locus_tag="JX887_001899"
     CDS             10180..11541
                     /locus_tag="JX887_001899"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAX1257878.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            11501..12652
                     /locus_tag="JX887_001900"
     CDS             11501..12652
                     /locus_tag="JX887_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAX1257879.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12627..13796
                     /locus_tag="JX887_001901"
     CDS             12627..13796
                     /locus_tag="JX887_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAX1257880.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13971..15350
                     /locus_tag="JX887_001902"
     CDS             13971..15350
                     /locus_tag="JX887_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAX1257881.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15631..15860
                     /locus_tag="JX887_001903"
                     /pseudo
     CDS             15631..15860
                     /locus_tag="JX887_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5185 a         2799 c         3378 g         4498 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata gtgttgaatt
     4621 tatgttttta tgtataaata gcttctaata gttcgggtat tttgttttta taaccatttt
     4681 tattcttatt tttaaaaaaa tatttcgaaa tatactagac aattcagaaa attttgttta
     4741 atattattcc aataaaattc aaatctttat caaatgaaat tccaataaaa acggaaaaaa
     4801 agtgaaaaga ggaatgaaaa aatgacagaa ttgataattg gcggagtcac agcaagcaca
     4861 ttggcagaaa agtataagac acctctgtat gtgtatgatg aagaaaagat gagacaaacg
     4921 atgctgtcat tcaagcgagg ctttgtatcg aaacgttttg atacaaaagt gctttacgcc
     4981 tctaaagcat tccaaacgat tgagatgctg catttagttc gtgaatatgg attcgggcta
     5041 gatgttgtca gtggtgggga aatctatacc gctttgcaag ctgattttcc tagagatact
     5101 atctacttcc atggtaacaa caagacgcca gaggaactga tctatgcact tgaaaatgat
     5161 ttgttgcata ttgttgccga taatttgatg gaagttgaat tattagcaga attaagccaa
     5221 cgctatttaa aaaaaatctg tatcatgctt cggttgaatg tcggagtaga agcacatact
     5281 catgaatata tcgtcactgc gcatattgat tcaaaattcg gcatgagcta tgaaagtaaa
     5341 gagtgccaac aagcccttca gttgataaaa gaaagcagct atctagagtt agaaggattt
     5401 catgctcata tcgggtcaca aatttttgat gttactgctt ggttagctga aatcgacaaa
     5461 ttgacgaatt acttaaccga ttttgaccaa cctctttcct tgaatcttgg cggagggttt
     5521 gggattcgtt atacacaaaa tgatcagccg atcccagtcg aagaggcact aaaaaaactg
     5581 attgaatata cggaagaagc tttggaaaaa cgaaaactga ccattcgtca attactgatc
     5641 gaaccgggta gaagtattgt tggagaagct ggtacaacac tatacacgat tggtttcatc
     5701 aaaaagacac cacataaaaa atattacttt gtagatggcg ggatgacaga taatatccgt
     5761 ccagctctgt atcaggcaga atacgattgt gatttagcag caaaactgtc ggaagaaaaa
     5821 acagagaaag tgacgattgc aggaaaaatg tgtgaatcag gcgatgtggt aattaaagaa
     5881 gcttatttgc cgaaagcaga atcgggtgat cttttagctg tttattccac gggagcttat
     5941 ggatactcga tgagcagcaa ctacaatcga gcgacacgac cagcagttgt ttttgtcaat
     6001 aatggccaat caagactgat tgttcgcaga caagcatttt ctgatctact aaggggggaa
     6061 gtttcctatg atccttcata aatataatgg ctgcggaaat gattttatct tattagatta
     6121 cgcagaagac acagattata gtcaattagc cgcttcttta tgcacaaaag aaaaatatga
     6181 tatagacgga ttgatcgccg taaaaatcga tccgttggaa atgatctatt acaacaaaga
     6241 tggcagccgc gcgccgatgt gcggaaatgg cattcgctgt tttgctcgat acgtaaatga
     6301 tcagaacatg atgaatgaac aggaattcaa cgtagagaca ttagcaggca caagaaaaat
     6361 tacggtgttg gatccctcac ctttttattg cagcgtagat atgggagtgc cagatgattc
     6421 tccggaaaaa atcaaagcta atcaaactta tccaataaaa aaccaggaaa tagagatcaa
     6481 tggtgaaaaa gtaacgatca ctagtttatt tttaggaacg attcataccg ttgtttttgt
     6541 tgaaaatgcg cgtgaggaag tctggagaaa aagaggtgaa ctgatctgtc atcatccttt
     6601 gttcaaagaa aaaaccaatg tcaactttgt agaagtagtc aatgaacaag aattgatcgt
     6661 ccgtacctat gaaagaggag taggttggac acttgcttgc ggtacaggtt gctgtgcctc
     6721 ttatgtggtt gctaaggaaa ctgggaaaat ttcagcagat caggtagttg ttcacttgga
     6781 acaaggagac ttgatgatct ctggtgagga tgcgatacaa atggctggcc cagcagttca
     6841 tgaatggaca agaatattgg aggaatgaag atgataaaag gttcgatcgt ggcgctgatc
     6901 acgccgatga atgaagaggg atcagtagat tatgctggtt tggaaaaatt gatccaattc
     6961 catttagatg aacaaacaga tggattatta gttttaggta caacaggaga atcttctacg
     7021 ctcacacaat ctgaggagga gcagatcctt caactgacag taaagaaagt ggctggccgt
     7081 gtgccggtga ttgcaggagc tggaacgaat aatacgaaag aaacgattga aaaagcgaag
     7141 cattttgctt ctttgggggc agacgcactt ttggtcatca ccccttacta caacaaaaca
     7201 agtgatgcag gactagctgc tcattttaca gcaattgcag aagcctcacc gattccgctt
     7261 attttgtata atgttccttc tagaacaggc atgtcgattc caatccatgt attagtaaat
     7321 ttagcagaac atcctaatat cattggtttg aaagaagcct caggagatat ggcttatgtg
     7381 atggatgccg ctcggttgat tggagaagaa ttcttccttt acagtggaaa tgatgatttg
     7441 atcctaccag taatgagtgt aggaggaagc ggtgtaataa gtgtatgggc gaatatccaa
     7501 cctaaaatag tccatgaatt agtaaaagat acgcaggacg gaagatggca gcaagcaaaa
     7561 gaaaagcaat taaatgcact tgaactgatc catgccttgt tcagtgagac caatcctatt
     7621 cctgtcaaag cagccatgtc attattagac ttaccttccg gacctctacg cctgccttta
     7681 gtttctcttt caaaagagaa aaagaaacaa ttagctcagc ttttgttaaa agaaaggacg
     7741 gttgaaaaat gaaaatcgga ctgattggca gtggacagat gggaaataga gtcgaagaag
     7801 ttgcacaaga aagaggagat acggtccttc ttttacggac ggcacctaaa gaagcaacta
     7861 cgcttgcttt tacggaactg ccagaactgc ttattgattt ttctcatcca gataatttag
     7921 agaaaatcct ttcgtatagc ttatcatatc aacttccgtt agtcattggc acgacaggtt
     7981 atacacaatc acagttccaa gaaataaaag aacatgccaa acatgtacct gtgatgtata
     8041 gtgctaattt ttcgttcggc atcatggtga tgaatcaact aatcaagcaa gcagctgcaa
     8101 tgttgcaagg ctggcagatc gaactgattg aaaaacatca tagtcgtaaa aaagatgcac
     8161 catctggtac tgcaaatatg ctgcttcaaa caatccaaga agtgcaaaag ctgcagcccg
     8221 tatacaactg gcaagggaaa aaaagagaag aaaaccaaat tggtgtacac agtattcgtg
     8281 caggttcttt acctggtgaa catgatgtat tgtttgctgc tactgatgaa atatttacga
     8341 tcaaacatga atctttttct aatcgaatct ttgctgcagg cgcagtagaa gcagcggact
     8401 ggttgaaaga tcagtcacca ggttattaca aattagaaga tttattaatg gacaaagggg
     8461 tgtaaaaaac gtggaagctc aagaaatcat ccgctacatt caaacggcat ctaaaaagac
     8521 gcctgtgaaa gtctatctga atgtaaccga gccaatcgaa tttaaagaaa gtaaagtttt
     8581 tggtgaagga agcagcttcg ttgtttttgg tgactatgag acgattgctc cggttttaga
     8641 agctgaatca gaaaaaatca ttgaaatcga aatcgaaact gctgcaagat acagcgcagt
     8701 tcctttgcta gatattaaaa aaattaatgc tcgtatcgaa ccaggtgcta ttatcagaga
     8761 tcaagtgtca atcggcaaca atgccgtgat catgatggga gcgattatca atattggtgc
     8821 agtaatcggt gaaaacacga tgattgatat gggtgctgtc ttaggtggac gagcgacagt
     8881 gggcaaaaac tgccatattg gtgcaggagc tgtcttagca ggtgtgatcg aaccagcatc
     8941 ggccaaaccg gttatcgtag aagacggcgt actggtaggt gcgaatgcag tgattgttga
     9001 aggtgtccat atcggaaaag atgcagtcgt ggcagcagga gcagtggttt tagaagatgt
     9061 ggcagcagaa actgttgtcg gtggaatacc tgcacgtgta ttaaaaataa gtgatgatca
     9121 gacaaaagaa aatacagcat tgattgctgc gttacgcgaa ttatagagga gatggagaaa
     9181 aatgcgcgaa atagatacct gtattgtggg ggcaaccgga ttagtcggcc aaacgatgct
     9241 caaagtgtta gaagaatatg attttccagt aggacgattg aaattattag cttcaaaacg
     9301 ttcagccggt aaagtttgtg tattcaagaa aaagaaacac actgtacagg aattgacaga
     9361 aacttcattt gaaggatatg atttagcgct attttctgca ggtgcttctg tatccaaaga
     9421 gtttgcgcca atcgcacgaa gtcagggact atttgtcata gataattcct cagcatggcg
     9481 ggaagattcg gatattccat taatcgttcc agaggtcaat ctggaagact atacattgaa
     9541 tcggctgatt gcaaatccaa attgttcaac cattcaagcg gtacttccgc ttaaagcttt
     9601 acaagaagcc tttggtatcc agcgagtcaa ttattcgacc tatcaagcag tttctggttc
     9661 cgggcaaaaa ggcattgaag atcttcatcg tacgcaaaat gacgaggaac cagttttgta
     9721 tccttataat attagccaaa cggtgattcc ggaaatcgat cagcctttgg aaaatgggta
     9781 tacaaaagaa gaacagaaaa tgataaatga gacccgtaag attctgcatc agcctgcttt
     9841 gccagtatca gcaacctgcg tacgtgtgcc aatcgaaaat ggacatggag tctctgtggc
     9901 agttcaactg caaaaagagt ttacgacgga agaaattaga gagtgtctca gccagtttcc
     9961 agggattcaa ttagaagatg atctagcagc acataaatat ccgacgagca ttcttgctag
    10021 aggaacagat atggtttatg ttgggaggat cagaaaagac acttctttag agaacggatt
    10081 gttgttctat acgactgccg ataacatacg caaaggagcc gctgcgaatg ccgtacagat
    10141 tgctgcagct ttaatgcaga aaatagcgga ggtggcaaga tgagtaatac gctgaaagta
    10201 gcgaaattcg gcggaacatc gatgtctcat gaagagcaat tcaaaaaagt ccgtacaatt
    10261 gttctttcag atcccaatcg ccaagtgatc gttgtttctg ctttaggcaa acgtacgtca
    10321 gatgatgaca aagtaacaga cttactttat ttgatttatg cttaccttca gcatcatgtt
    10381 gattggacac ccctttggaa aaggatttgt gatcgtttca ttcaagtaag agatgttctt
    10441 gccctgcagt tacctattga agatgaacta gcacgcatac agaaacaact ggaagacgaa
    10501 aagataactg aagattattt agtaagtaga ggtgaatatc tgactgctca actgatggct
    10561 gagtatcttg gttaccagtt tattgacgca aaagacctga ttttctttga ctatgatggg
    10621 aaaatcgatc aggaaaaaac agcacaggaa atcacaaaag catttaaaag atatccgaaa
    10681 atggttgttc cagggtttta cggggcgaac cctgcaggaa aagaaaaatt attgggccgt
    10741 gggggaagcg acattaccgg cgcgatactg gcgaagatgt tgcaagcgga aagttatgag
    10801 aattggacgg atgtttcagg aatcatgatg gctgatccgc gaatcatcga tcatcctaaa
    10861 atcatcgagg aaatctcttt tagagaactg agagagatgg cttatatggg ggctaacgtt
    10921 cttcatgaag cagctgtttt cccagttcaa gaggctgata tccccatcca aataaaaaat
    10981 accaatgatc ctttcgctca agggacaaaa atatcgaatc acgaaataga aaaggaaaat
    11041 ggactgacag gaatagctgg acgcaaggat tttctttcca tcactttatt caaacgtcat
    11101 atgtccgatg aaatcgggtt tatctggaaa gcaatgagca tttttgctaa acatgagata
    11161 tcaatcgaac atattccttc agggatcgac aatatcggag tgatcgtctc agcagaagcg
    11221 attgccgata agttatttct catcacgaaa gaattaaaag aaacacttgg cgtggaagaa
    11281 atcgtcgtga tcgaagactt agctttgatc tctgtcgttg ggggtccgca taaagaattg
    11341 attggattat ctgggaaagt gttatcgata ttgaacaaat tagaaattcg cacatcgatc
    11401 ttatcacaag gagcacagga gttgaatctg atcatcggtg taccgaataa tcaatatgaa
    11461 acagtagtga agggtatcta tgaagggatg gtgaatacgg atgctgaaag aatatcgaat
    11521 ggcactccat caaattcctg aaatcgggtt tcatgaattc aagacaaaaa aatatttata
    11581 tgaacaagta aaaaacagcg aggccgttat ccatgaaatc ggcgaaacag gactactcct
    11641 ttattttgat aatcagcaag aagaaacgat tgcttttcga acagatatcg atgcactgcc
    11701 agtcaaagaa gaaacgaatc tctcttttgc ttctaagcat gaaggttata tgcatgcatg
    11761 tggtcatgac ggacatatgg cgatgctttt agggttgact gactttataa ctaaacacat
    11821 tgaggatctt atttataatg tagtactgat ctatcagcca tcagaagaaa tttccggtgg
    11881 cgcacaaagc gttattcagt caggattgtt ggataaatat gaagtacaag caatatttgg
    11941 ctttcatcta tggcctggac tagctaaggg agaagttttc tctcgaccag gacctttgat
    12001 ggcacaaagc agtgaaacag acattatcat taaaggccag tctgcacata ttgcttctag
    12061 tgaaaaagga atcgatagtc tggaggcagc tgtacgattt ttgaagaatg tttatgattt
    12121 tgaccggcaa ttaccggcag agtggaatca tctaatgaaa tttggccaaa tccaaggtgg
    12181 aacgatccga aatgttttag ctggagaagt tattgtatcc ggaagtatcc gttcttacag
    12241 ttcagatatg caaaattatt tgaagagggg attagaccat ttagcagaac agtttcactc
    12301 tacagctact atttcttttc gctataatga cggctatcca gctgtaatca accatagagg
    12361 cttatatgca gcactgttag attcaaacaa actacatgaa ttagatgctc cagttcttca
    12421 agccgaagat tttggcatat atacgcaaca atatccatgt gtatttttct ttttaggtgt
    12481 cggtgatacc cctgctttac atgatccgac gttcgatttt gatatggatg ttttagaaaa
    12541 tggtgtagaa tggtacaaaa cgattctttt tacagaaaat cttcttgtaa aaatcgatag
    12601 cagttcaaaa gaggagcgag taaataatga tgaatttatc caatcgattt agtcctaggc
    12661 tttctagaat agaagtatca aaaatacgac aattcgatca gcaaatatcg tcgataccag
    12721 atgtgatcaa actcaccctg ggagaaccgg attttccaac tcctgaacat gtcaagcaag
    12781 caggaatagc agcgattgaa gaagactttt ctcactatac cggaatgaga ggattagagg
    12841 aactgcggga agcggcttgt atatttcagc aacagcgtta tggattaact tatgatccgc
    12901 aaacggaagt tttgacgaca gttggtgcaa cggaagcgat tgcctctgcg ttgttatctg
    12961 ttttggaaga aggagacaag gttcttattc cagcgcctgc ttattcagga tatcagccat
    13021 tagtggaact agctggtgct gaattgatcc cgatagatac ttctgacaca gggtttgtct
    13081 gtcagccgga acaatttgaa cgagcatttg aacaatatgg atcagctgtc aaagcagtca
    13141 ttttaaacta tcctaacaat cctactggga cgacattgtc tgcaaaacaa ttgaaagcaa
    13201 tcgctgaggt tttaaaaaaa tatccggtat ttgttataag tgatgaagta tatgctgaat
    13261 tgacttatag tggaacgcat atgtccatag ctacttatct tccagaacaa acaatcgtga
    13321 taagcgggtt atccaagtca catgcgatga ctggttggcg agtgggcttt atttttgctc
    13381 aaaaagccct tattgacgaa ctaattaaag tccatcaata tctggtgact gccgctacaa
    13441 cgatgtcgca aaaagctgcg gctgaagcgc taataaatgg ggtgaaagat agcgagaata
    13501 tgaaagagca atatcaaaca cgaagagact atctggtcca gcaattggcg cctttaggat
    13561 ttgaagtgac ccagccaaac ggtgcatttt acttgttttg caaactccca gctgccattc
    13621 aaactgactc ttggcagttt tgtgtagaat tagcggaaca ggcaaaagtt gcgtgtatcc
    13681 caggaattgc atttggccca gaaggagaag gttatatccg gatttcttat gctagcagca
    13741 tggaaaaatt acatgaggcc tgcaaacgga tcaaagactt tttaacagaa cagtgattca
    13801 tagattttat caaaaaaaca atcgttaatt ttgcggtata ttctgcaagg agacgattgt
    13861 tttttaaatt tagttcaaat gaacgcgttt cttttgattc ataactaatg taatgttaag
    13921 tttaaattgt ttagaatgat tttaaaagaa tattcaagga ggtttcatca atggaaaaaa
    13981 tcaaagttgt cattgtaggt gcatctcatg gagggcatca atcgatcttg gaactattga
    14041 cacgatacgg tgaaaatgta gatatcacgc tatttgaagc aggagactat atttccttca
    14101 tgtcatgtgg tatggagctg tatttagaag acaaggtaac agatgtaaat gatgtacgta
    14161 atttcagacc agaaaacttt ccgcaatcca atgttcatat tttaaataat cacgaagtaa
    14221 aaacgatcga tgccgataaa aaaacagtaa cggttactag cgcatcagat aacgaaacaa
    14281 aagaatatcc ttatgacaaa ttgattttga gttctggtgt caaaccaaac aatctgccag
    14341 taccaggagc agatctagaa aatgtctact tgatgcgtgg atacaattgg gcaaccaaaa
    14401 tcaaagaaaa attaaatgat ccggctatta aaaaaatcgc tgtcgtaggt gcgggttaca
    14461 ttgggatcga agcagcagaa gcaagccgaa aagctgggaa agaagtcgta ttgcttgatg
    14521 tgatcgatag acctttaggc acttatttag atgctgagat gacagatatt ttagaacaac
    14581 acctaaatga aaacggtatt gaagttttga caaatgcaaa aatcgaagct tttactggta
    14641 acggaaaagt tgaggcaatc aaaacaagtg aaaaagaaat cccagcagat ctagtcattc
    14701 aagctgccgg tgtgaaggca aatacagaat ggttaaaagg gatcgtcgac ttagatgaac
    14761 gtggctggat ccaaacaaat gaatacttgc aaacgaatct tccagatgtg tatgcagtag
    14821 gagatgctac acttgcttat tctatcccag cacgcaaaaa aatgccgatc gctttagcga
    14881 ctgttgcacg tagagaagca cgttatgtag taaaacatct ttttgaagaa gtaccaaaca
    14941 aaccgttcgg cggagtcgta ggttcctctg cattaagtgt ctttgactat cattttgcag
    15001 caagcggatt gaatagcttt acagcagcaa aagcaggagt agatgtacga gtgtcttatt
    15061 atgaagatac gttacgacca aaatatgtac cagaagaaca aggaaatcca aaagtgtcca
    15121 tccaattatt ctcggatcca atgacccatc aattgctagg aggagcagta ttatctacct
    15181 atgatgttac aggtcaagga aatgtattgg cactagcgat ccaaaacaaa ctgactttag
    15241 aagaactagc agaagctgac ttcttcttcc agccaggctt tgaccgacaa tggagcatgt
    15301 tgaatctagc cgctcaacaa gcgttaggag aagaaccatt tgtagaataa gaaaacgaaa
    15361 tatttgaaaa gaggttgtga aaaagctgcc ttgcatcaag taataagaac agccaagtaa
    15421 aaacagcttc ttatgttttt aacttggctg gacttattac cgcagatgca agcttttgaa
    15481 caccgtttat tttcaaaaaa gggactgtga cacgatttgt gtaccgaccc ccaaaagtta
    15541 gaccaaaaaa tctaactttt ggaggtcggt attttttatg gttaaatata cttttgaact
    15601 taaattaaag atcgttcatg attatttgga tggcaaaggc gattggaccg taaaaatcca
    15661 gatcaagaga ttgaagcgga aatgcttaaa attcgggaga agcacaagga ttatggctgt
    15721 ttacggatga ccaatgaact aagaaaccgc ggtttctcta tcaataaaaa gaaagttcag
    15781 cgcttgatca agaagctagg aataaaagta acggcataca cgcgtaaatc acgtcgctac
    15841 aattcttatc gaggaaaagt
//
LOCUS       DADGHT010000065        15812 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.065, whole genome shotgun sequence.
ACCESSION   DADGHT010000065 DADGHT010000000
VERSION     DADGHT010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.065"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            68..751
                     /locus_tag="JX887_001904"
     CDS             68..751
                     /locus_tag="JX887_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAX1257882.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            753..1589
                     /locus_tag="JX887_001905"
     CDS             753..1589
                     /locus_tag="JX887_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAX1257883.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            1600..3354
                     /locus_tag="JX887_001906"
     CDS             1600..3354
                     /locus_tag="JX887_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1257884.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(3630..3971)
                     /locus_tag="JX887_001907"
     CDS             complement(3630..3971)
                     /locus_tag="JX887_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAX1257885.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(4039..6210)
                     /locus_tag="JX887_001908"
     CDS             complement(4039..6210)
                     /locus_tag="JX887_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAX1257886.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            6421..7278
                     /locus_tag="JX887_001909"
     CDS             6421..7278
                     /locus_tag="JX887_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAX1257887.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(7349..8206)
                     /locus_tag="JX887_001910"
     CDS             complement(7349..8206)
                     /locus_tag="JX887_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1257888.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(8191..10893)
                     /locus_tag="JX887_001911"
     CDS             complement(8191..10893)
                     /locus_tag="JX887_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAX1257889.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(10906..12195)
                     /locus_tag="JX887_001912"
     CDS             complement(10906..12195)
                     /locus_tag="JX887_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAX1257890.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            12345..13391
                     /locus_tag="JX887_001913"
     CDS             12345..13391
                     /locus_tag="JX887_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1257891.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            13393..15546
                     /locus_tag="JX887_001914"
     CDS             13393..15546
                     /locus_tag="JX887_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAX1257892.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
BASE COUNT         4491 a         3303 c         2919 g         5099 t
ORIGIN      
        1 ttgctccgtc ttcttctctt gctgttctgc ttcattgcct ataaaccttt atgaaagaag
       61 agataacatg cctactatcc atattgccgg tgattctact gcggcagaaa aagatgaaaa
      121 caagcgtccc gagacaggtt ggggagaaaa aatctctgct tatttttcac ccgagatcca
      181 gatcaataac caagcaaaga atggacgcag caccaaatca tttatccagg aaggaaggtt
      241 agcccgtcta gcttcacagt ttcagccgaa tgatttctta tttgtacaat ttggacataa
      301 cgaccagaaa atccaagaag aaagaggtac gcttcccttc ggtagctatt taaaaaatct
      361 gcagatattt tttgaatgcg caaaaaaagc gaacgtccaa atggtcttac tgacatctgt
      421 gacgcgacga gattacttag aaaacggaac attgaatcca gatatacttg gagactatcc
      481 aaaagcgatg cgtgcatttg ctgagaaaca ccatattcct cttttagatg tgttctcaag
      541 atcacaagaa ttgttccaga ccttctcaaa agaagagaca aaaaaattct acctgcatct
      601 tatgcctgat acttgtaaaa attacccaga aggactaaaa gacaataccc actttagtcc
      661 agaaggcgct gataaagttg cccgaataat tgttgaattg ataaaagaat cccgtctgcc
      721 tcttgctaat tatttacaaa aaggagtttg agatgtttcc attaaattta ggcatccgtg
      781 cccacgattt agatgttcga aatcgtgaag aaatcgttca aaaagtatca cagcttcact
      841 tgtcccatat ccaatttgca ccacaaaaag catttcctga acaacttaaa ttaactgaca
      901 tgacacttgg gagtgctgcc tattttggtg aatacttcca aaaaaacaat atcgaacttt
      961 ccattttagg atgctatatc aacctatcca gcaaaaatca agaagttcgt gcacaagcat
     1021 tggcaacttt caaacagcaa attgctctgt gctctgccta tcaagccaag atgattgcta
     1081 cggaaaccgg tagtgtctct gtcggttaca caaaagaaaa ttttactgaa gaagcttatc
     1141 agatcgccag aaattctatc attgaattag tcgctcatgc agaaaatttt ggcgtaactg
     1201 ttgctgttga agcagggatc aatcatccaa tctataacta tcagttagct aaacgtttaa
     1261 tcgatgaagt agcttcacca aatttaaaaa tcattttaga ttgtgcgaat ttgatgcata
     1321 aagaaaatca tgctgatcag gaaaaagtga tccgaggtgc cttggacaat ttacatggtt
     1381 atattacagc gcttcatctc aaagactata tcatggaaaa tggaaagatc cgcatggtac
     1441 ctgttggcaa gggctgttta gatttccgcc cggtactgca ttatatcaaa tatgagcgtc
     1501 ctctaatgta cgccactctt gaagctactc ctgagattta tgttcctgaa gcaatagaac
     1561 acttgcagtt tatttaccaa gattgttaag gagaagatta tggaggaacg aatacagaaa
     1621 agttatcaaa aatatcatgc aaatgctttt cagacattgc tgcatcttta tcagggaaat
     1681 tattggcgtt ttgccatgtc aggactcttt tttattatca aacatcttcc atcttggtta
     1741 atgccgatcg ctattgccaa tgtaatcaat gcagcttcat cgaaagattc ttctcagttg
     1801 caggccattt atttcaacgc ttttttgatg gcttgtctga ttggtcaaaa tatattgacg
     1861 aattattttc atgtaaaata ccatagcact tcgatccgtc aagtagaagc tggactaaga
     1921 gcgaccctta tcaagaaaat ccaagaacta tctattcctt atcaaaaaga attgcaatct
     1981 ggacgaatcc agtcaaagat catccgtgat gtagaagcta tccaaacgtt gtcctctcaa
     2041 gtatttgtca gcggattaaa tatcgctgtc aatttattcg tagctttagg tatcacgctt
     2101 tataaaagtc ctgttgtttt catgtttttc ttattgactg ttcctctcgc cgcattcgtt
     2161 actctctttt tccgtaaaag gatcagacag tccaactcag acttcaggca agaaatggaa
     2221 gagacttctg caaaagtgat cgaagtgatc gaattagcac cgattgctcg agctcatggg
     2281 ttagaaaaac acgaaacaac tcgcttaaat aagcatttta ctcaaatcta tgaaaaagga
     2341 ttccacttag atatcctgca atctgttttc ggatcagtca gctgggctag ttttcagata
     2401 tttcagctga tttgtttgag tttcactggg atattagctt tacaagggcg catccaaccc
     2461 ggcgatgtcg tgatgtatca gacgtatttc acgacgatcg tcaattccgt ttctggaatg
     2521 atcacgctga ttcctacgat ttcaaaaggc atggaatcta tcacttctat tggcgaactg
     2581 ttgattgctg gcgatgtaga aacttatcac ggtaagaaaa aaatccaaca tttggatgga
     2641 aattttcgtt ttgaggatgt ttcttttctt tatccggact cactcaaacc gattatcgat
     2701 catttttctc tagaggtgaa agctggagaa acaattgctt ttgttgggcc atctggctct
     2761 ggaaaatcta cactccttaa cttattgatt ggatttatcc agccgacttc aggaaaaatt
     2821 tttctagatg atcagccttt ggatgaactg gatatgcgaa gtgtgcgaaa ttatttagcc
     2881 gttgttcctc aaaccacttt gttgttctcc gcttcgatca aagagaacat cacttatggc
     2941 ttgaaaaacg tatcaaaaga acgtttagat gaagtcatcg aagctgcgca actttcttca
     3001 ctgattgacc agcttcctga tggtctggat accttagtag gcgaacatgg caacaagctg
     3061 tctggtggcc aaaagcaatg tatctccatt gcacgagcgt tgatacgtca gccaaaaatc
     3121 attttgctag atgaagcaac ctcagcttta gataaccagt cagagaaaaa aatccagcaa
     3181 gccctgaatt acctgacaga aacacccact acttttattg tggctcatcg gctttcaacg
     3241 atcaaagagg cagataaaat cgttgtgatc gatgaaggaa aaatcgttga aataggtact
     3301 tacgaaaaac tgttagctca aaaaggctat ttctaccgct tgaaaaatga atgacaaaaa
     3361 ataggagcta tgacaagact tttgtcgtag ctcctatttc tgaataaacg gtgttctcct
     3421 gccaactcct cggtcacaag tcacaatagt catcaaacat gagaagctgt tttttgaaat
     3481 tgttccttgt aactcagagt taaacggtag gctcacgacc tcttggtaaa tggtgttcaa
     3541 gagacagcct atcggcaata agaagcaatt ttgtcatcgc tcaaggccga acgtctcttt
     3601 cacaccctct gttgtttcat aaaatagttt tattcgctgt aaaggtcgcg aactggtgtc
     3661 atgatgatac ggttcaagtc attgatgatt gtactgaagc cttgctcttt ttgcatcaag
     3721 tcattgatta cttcttctga ttggattttc acagccattt cttgtgcttt cattgcatct
     3781 tcgtcgctga actcttgtcc actcatttgt ttttcttgta attcgatttg catcgcttgg
     3841 aagtctttga acagtttgtg tgcttcttcg tttgcttgta ctttctcgta cgcttctttc
     3901 aacgctttga attctggtaa ttcacggatc tcacgttcga tttgattcgc gctatcgtag
     3961 atgtttgaca tgttatgccc tcttttcttt tagtagttac tctctattgt aacatggggt
     4021 tattcgtttt caaaggggct actctccttg atatttccgc cagaggtctt tagccgcttc
     4081 accaattccc tgaacgcctt ctttcaccat atcgccgaag tttttcagcc cttcttttgc
     4141 ttgttcacca tattgattca agttatcttg ccaatttcca gactctccat tagaatttcc
     4201 tgtgtttcca acttgatctg cagctaccac ttgtcctcct gtggcatagg catctgctac
     4261 actaaatcct gtttttgaag tatacggaag gatgccttct gccgctgatt tgaagacttt
     4321 cccgacaaca tttccacttg tcccttccaa atagtgcagc ttgctggatt cttcgtaacc
     4381 catccatgtc gaaatcacta cgtctggcgt gtaaccgatc atccattggt catttgcttt
     4441 tgtggcatcg aaattagttt ctgtggttcc tgttttccct gctatcgtat aacctgcagg
     4501 attcgcagca gccgctgttc catttgaaaa tgtaccaaga agcatgctgg tcatttcatc
     4561 ggctgtttcc tttgatatga cctgttttgg ttttttgttt gtgttatcga cgatcaccgc
     4621 tccagtcgaa tcaacgattt tcgtgataag atgcggcgta tacatctgac catcattggc
     4681 aaatgcactg taagcacccg ccatgatcaa tggagatact cctttttcca gtccaccaag
     4741 ggctaagcca taatacttat cagattttgc taaaggcagg ccgaattctt ctgctttatc
     4801 atatcctttt tgtaaaccga tctcatgcaa aagccataca gcaggcaaat tcaaactttg
     4861 tgcaacagct tgatacatcg gtacttctcc ttggtatgtc ccgtcaaaat tatgcgcatc
     4921 gtaataactt tgcggttcgt ctttcaagat actggaaggc ttgtatccag cttccagtgc
     4981 tggtgtatat acgcttaatg gtttgatcgt tgatcctggt gaacgacgca tctgtgtagc
     5041 aaagctgaat cctctaaaga catgatctcc tcttcgtcct actagtgctt gtacaccacc
     5101 tgtattcgga tctaaagcta ctgaagcaga ttggaccatg gcaccatctg aagcatttgc
     5161 tgggaataat gcactgtttt gataagtagc ttctaattgc ttttgataat cctgatctaa
     5221 agctgtatag attttatagc ctttattcat gacatcttct tcatcaagac catactcgtt
     5281 aactgcttca tcgatcactg catcaaaata ataaggataa cgataaccag aatctgaatt
     5341 atcgtatgtg tcattaagat acgcgctgat atctgtctgg ctttctgctt gttcttgttc
     5401 ttttgtgatt tttccgtttt cttccattac acttagtact gtgtttttcc gatcattcgc
     5461 attttttggg tgatcgatcg gattataaat accaggacct ttcagcattc ctgccaaagt
     5521 agcagcctca gacagcgtaa cattcgttgc atctactcca aaatactttc tggaagcgtc
     5581 ttggacaccc cataccccgt tgccaaaata ggcattgtta agatacatgg tcaagatttc
     5641 ttctttgctg tacttctttt cgatctcgat tgccaaaaat aattccttcg cttttcgatc
     5701 aaacgtttgg tctaatgtca gatacgcatt tttggcaagc tgctgagtga tcgtacttcc
     5761 tccgccccct gatgttccgc cagacaagac cattcggact gctgcacggg caatcccttt
     5821 gatatcaaac ccgtgatgct cgtaaaaatt cctatcttct gtcgagatta ctgcatcttg
     5881 gatataggga gaaatcgcgt ttaattctac atatgttcct ttttgggcgt acagtgtgcc
     5941 agcttcttcg tttttcttat cataaatgac tgtcgattgg cttaatcctg attttaacgt
     6001 ttcgacattt gcttgttttg ctaaaataaa gaggtagata cttgtcacta agacacagat
     6061 caaaccaatc agcaaaatca atttgttcac atgatatttt ttccagatgc gctttcgcca
     6121 tcgatggaat tgtccgagat atggtctgat ccaacgccaa aaactgatca aagcagcttt
     6181 tatcttttct aaaatgcttt gaaaatccat ttgcttcttc tcctgtctat ttgattcaat
     6241 cgtcttattt taccatagtg aaagagtgtt ttcttcctgc ttaagttgta gttcaatatg
     6301 tttttttacg ttagtgcaag tagagtaaca taagaatgaa cagaaaaatg taagtttttt
     6361 cttaaatatg ttttaaaaat ggtacaatta gtctgcaatt gcactgaaag gagtacactt
     6421 gtgaaaatca cgatcacttt acctatgaac catcctgaaa caacaattcg cgacttgctt
     6481 gaaaaggaat ggttagttcc tagaaaggtt cgacactttt tgcgtatacg taaaaacgtt
     6541 tggatcaatc aacaacctgc tttgttccat catgaagtaa agggcaatga ccagatcaca
     6601 ttgttattcg aagaaacaga ttataattat caagaagttc aattaggaga tgcgaagcac
     6661 atccgtgttt tatatgaaga tgagcatttg attatagtgg ataagcctgc aggaatgaag
     6721 actcatccaa atgaaccgac agaaaacagt accttactca atcatttagc tgcttatctc
     6781 gacactaaac agcaacgacc ttacgttgtc caccgcttgg acaaagaaac aagcggtgcc
     6841 gttttatttg caaaaaatcc atttgtcttg ccgatacttg gaagaatgtt ggaacaaaaa
     6901 atgatctatc ggagatatca agccatcgta tggggagaaa ttgccaaaga tatgaccatc
     6961 accaataaaa ttggacgaga tcgccatgat cggagaaaaa gggtcgtaga tgataaaaat
     7021 ggtcagagcg ccttgacaca tgtcactgtc aacaaagtac tttctgaaca aacacaagtc
     7081 tattgtgttt tggaaaccgg acgtacacac cagatcagag ttcatttagc tcataaggga
     7141 catccgatcg ttggagaccc tctctaccaa aatagaacag ctgaacgact gatgctccat
     7201 gcattagaac tgcacatgat ccatccattt actcaagaaa aaatagtcgg taaagcttta
     7261 cctggattat gggaatagaa ataaaaaaga acagagtctt atcagcagat aatgataaga
     7321 ctctgttctt tttgtgtaat ttgtctgctt acttttgatg ttcgtgttct gctaacagca
     7381 aactaccgat aatcccactt tcattcggca gtccccaacg aacgatatat tcacttactt
     7441 gaggtgtttc catataacca cccatcaatt caacaaattg ctgacggatt ttttgaagga
     7501 gatgatcctg attcattacc ccaccgccta aaataatctt ttcaggtgct aacgtcaacg
     7561 tatagttgat cagtgcttga gcaatataat aagcctgaat agcccaaaca ggatgatctt
     7621 gcggcagatc ttgccctttg atccctgtgc gtgcctcaat agacggtcct gctgctaatc
     7681 cttctaaaca atctttatga taaggacaag taccttcata atggtcatct ggatggcgtt
     7741 tcacccaaat atgtcccatt tcaggatgtg cgatccctga aaaaatttct tcattgatca
     7801 cgacacctgc accgattcct gttcccacgg taaggtaaat acaactattt tttccttgtg
     7861 ctgctccttg cttcaattcc ccatatgcag cagcattgac atccgttgtc caagcagcag
     7921 gaatattgta gcgttccttg attgtgccaa gaaaatcgaa ttgtgcccac ccttttttgg
     7981 gagttgccaa aacgtatccg taattatctt ttgttttgtc gataccaatc gggccgaatg
     8041 agccaatccc gattcccttc aattcataac gatcaaaaaa ttcaaatacc tgatccaatg
     8101 tttcttctgg tgttgtggta gggatactta atttttctaa aatttctcca ccatctgaaa
     8161 ccgcacacac aaattttgtt ccgcctgctt ctattccgcc atacattcgt tttcctcctc
     8221 gaatccgatt gtccgaatct cataaggttg gattattggg acaaccgctt gcttcgttgg
     8281 ttcttcaagc agattcaata tgacagtttt tccattgtct ttagttattt ccaatttttc
     8341 taaatgacta gacatattga aacctcttac tactacttta tcactaaact tgctgcgttt
     8401 caaagctgta attgcaaacg tttcactttt tatcgttaaa tattgttgtt ttgaaatcaa
     8461 tgttccttca tgatgtttga tttgttgagt ggaaaaagga atctgtgctg cgtatgcatg
     8521 caaataagta gagaattttt cttctggtcc atgtagttca atgctgtaat tgaaccgatg
     8581 ctcacctaga cactgtgctt ctggtgttgg aaaatatccc caatcgccta gttctcccac
     8641 actgcgaagt agcgtcactg cgatttgtcc gtcttctgtt acttcatatt cattcaaacc
     8701 aaagtttccg actgttacac cgtactcttc atcatgaata ttgacaaatg cttgctgatg
     8761 ttgcggattc gtggggtttt cccaactttt agacacatgg tttgggcgct tcaccacttc
     8821 aaaaatacta tctgcttcgt gatgttccac atgtaacttt gtaggaaaca agacacgtaa
     8881 gcgatgatct ttcatctgat tgtcgagagt cgtttcaaag tcgatttttt tactatcttt
     8941 tctgattgtc atgattgttt ttatttgaag gattcgtttt tctttggatc gttctgcttt
     9001 tcgataacga aattccacaa ccatctgctg ttctttttct aaacgctcgt ctgcagaaac
     9061 agggatttcc atttcctgta gaatacttat ttttgctatt tccggtgtat ctactaatac
     9121 ttttacttca gagttttctt tgttactgga taggattggc tgatcacaga aaggttgttt
     9181 aaagatatac tcatttccta tatcgccgat atcttcaaaa atatgcagat tattcaactt
     9241 tcgtttgttt ttgcgatctt ccattgtaat ggtaccattt ttttcaatcg tcaaatgtag
     9301 agggccgttt tcgatgattc gtccactctg atgaatcatt gtttcctttt cttctgcttt
     9361 cgcttcccct tctacaagcg cgaatgtttc ccaagaaaat gctggcatgt tttctaatgg
     9421 taaagtcact ttgatcattc ttgccatata tggcacacgg aaacggtctt tcggcaaatc
     9481 ataaccaaat tggacagttt cttcagataa aatagctggt atagtggccc cactttttgt
     9541 ttctacatga tacttacgtt taggcaaatt ttctaactct tgatatagtt gttcaggtat
     9601 tccttcagcg aatctttttc tttctaattc gatggttatt tctgcttcac cagttttatc
     9661 cattcctgca gtatttacaa tgacaaatgg aaagctgtct tttgggaatc cggtcgtatc
     9721 gattgctgcg gtcagctgtt ctaaggaatc ttgtgcaaga tactttccaa cttcatctgc
     9781 tttttcaaaa cgaggtatca tttcccgatg gacagaatcg actgaacaac cgcaaatact
     9841 gtcgtgagga tgattttgca ttaatgtctt ccaagcataa tctaattgat catggggata
     9901 gtttccacta acttcataag ccatcgtcgc aagtggttct gtaatatttt ctagctgtcg
     9961 ctggaccttg gtattccatt gttttaagta aacccgagca gatgctgtat tggctaaagt
    10021 ataccagcca tccgtttctt gacttgtcaa ttctccttct actgagccta agtcttctgg
    10081 cacatctttt tgaactgctt ccagatagtc agtaaaatta gaatgaataa actcgtaatc
    10141 tggaaacagt tcatttgcga gatggattgc ttttgatata tctttttgta ccggttgatg
    10201 atcaacacca ttcatcatca ataagtggtt cgtagaggca tattgttctg catccgctaa
    10261 tttttgcttc caaaaggcaa gagctgcttc tttttctact ggaatctcat tcccgttgct
    10321 ataccaattg gcaaatagca gaccaaagat tgctgtttga tcagggcctt tccaccacat
    10381 ctctgagtat tgggaagaat agttttctgc ttccaaaact tgattatcaa agccaattgg
    10441 ttttacacca cggccaaacg ctgctgctga aataccagct tgtttcatta attgaggcgt
    10501 ctgtcccata tttccaaatg tatcgggaaa atagcctaac atgacagggg ttccccattt
    10561 acggctttct tccatgccaa tcagcatatt tctcacgttc gattccgagc tgataagaaa
    10621 atcatcttgc aagatataaa atggtccaat tctcaatttt ccttcattga ttgcttgttg
    10681 gattgcctgt cttttttctg gccttacttg aagatagtca tctaaaataa tcgtttgccc
    10741 atccaaatga aaactgttga aggacggatc aacttcaaat agctctagta gatcgtctat
    10801 caattcaatc agtcgcatgt gatgctgttc gtaagccatg taccattcac gatcccagtg
    10861 gctatgagaa atgatatata ctttcttttt catttacgat acctcctact tttctactct
    10921 aatatcaaag taatccatga ctaattcgca aaacatcata tttgcccaag aaaaccattc
    10981 tctcgtataa ttttcaggat tgttcacatc gaatccttcg tgcataaggt gtgttcctgc
    11041 gtcagttgct acaagtaaat tcaatatccg ctctttttca gatttgtctg acgttgtcat
    11101 tccttccata gctaatgcaa tcggccaaac gtatttttct ggcgtatggg aggatccaat
    11161 tccttttgcg tactttcctt catagaaata tggattttct ttactcaaca atgttcttct
    11221 tgtttgcaga taatcttcct cttgttcaga acaatatccc aagtaaggtg cggcgatcag
    11281 attgggcaca ttactgtcat ccatgactgt ggcgtttccc attccatcta cttcatatgc
    11341 ataaatcgtt tgcccttttt gattaaccgt tcgtccgtga ttctgaatcc cctcttggat
    11401 ctctttcttc aatttctgtg tttgctgtac aatttcttta tcatcgagta tcgtttgaaa
    11461 aatttcttcc acataaccta acacgaccac cgcaaacata ttggatggta ccagatatcc
    11521 ataacggcaa gcatcatcgc taggacggaa accagaccat gtcattcctg taaaagctgt
    11581 ttttgcacct cgcccgtcat tgatcagcgt atcttctttt cttgtcgtgt ctcgtacaaa
    11641 tgtataagga gagtgttcat gatcttgctc tgttttgaac acgtccaaga tttttttgat
    11701 accttcaata aaagattgat tgaattgatc agtttttcct gtatttttgt aaagaagata
    11761 ggccaactgt attgggtagc ataaagaatc aatttcatat tttctttccc agatccaatc
    11821 gttcattttt gtatgatctg tttggtggcc agcaccgtta gcttcttcgt tgaaggcatt
    11881 cgcatatgga tcgatattga tataaaaaaa ttgctttttg actaacccgc tgatcatgtc
    11941 agctaattcc tcatcttctt ttgcaatcac taaataagga cgaacttgtg cagtagagtc
    12001 tcttaaccac atcgctggaa tgtctcccgt caataaaaag gtggttccgt cattttgctt
    12061 tttgactgtt gtcaacagag tattggcaaa tgctgctgta aaattctttg cccagtccgc
    12121 atggatatcc ccacattttt gtgtgatatc ttccataaat ttctgcaccg attttggtat
    12181 atctttataa accactaata aaaccttctt tctatttgat atatctttaa agattatact
    12241 tcatacagcc aattatgtct acgctttcaa aaaatatctt tttatttact ttttcatcca
    12301 ttatggtatt atttgaatat gatatatcat taagaggtgt ttatatgact caaccattgt
    12361 accagacaat atttaatgat ttgcaaacgg ctattttaac tggtgaatta cctgtagaca
    12421 gccaactacc aactgaaaaa gaactttcac gtacctataa agtaagcaga atcacttcca
    12481 aacgtgcatt gactgaatta gagcaattag gacttattta tcgcgttcgc gggaaaggca
    12541 gtttcgttaa atccgcttct ccggaacaga ttcttgcttc tcctacaaaa acacgacgga
    12601 ttctgtttct tcttccatat gtcgctgatt tgtctgttgg tgattttagc aagggattga
    12661 accctgtgat gcaagataaa cagattgatg tcatgatgac gacgcttgac tttctacaaa
    12721 ataaaacagc aaaagagcta atcaatgaat ttgacggatt gatttattat gctcttgata
    12781 cagaacaaca tcttgactta ctttttgagc tttcattgaa agaattccct gtcgtcatat
    12841 tagataaaaa aatctatgag ttaccttttc ctaccgttct ttccgataat ttccaaggcg
    12901 gtgcgcttgc tgcctcttat ttgatcgaac agggacattc aaaaatcgct tatttgtttg
    12961 gtacgcagac tcatccacaa tccgttcgac agcgttacct tggttacctt gaagcattgg
    13021 acaaagctgg tttgactttc cacacttcac tggatgacaa aagcgcgaca ttagatgaat
    13081 tgctttctta tatcactaag tatgaagtaa ctgcttttgt ttgtgaaaac gatgttgtcg
    13141 ctatccagac catgaatctc ttgagacagc atggttatca tatccctgaa gatttttcaa
    13201 ttatcggatt tgatgatatc caagcagcag ctcttgttga cccgccactg acaaccatcg
    13261 cacaagattt tgaacagtta ggtaagcttg cgggagatgc tttggtcact tggttagaga
    13321 caaaagatcg accatccgat agtaaatttc cagtttcatt catcaaaaga caatcaacaa
    13381 aggagaaata aaatgaatat cggtcaaata gatactagac atgcaacagc gaatcagcca
    13441 aatttctcta atgggaactg ccagccttat actggcgttc cttttgggat gaattatttt
    13501 gcaccgcaaa ctacggatca aaacggcagc tggtggtttc atcctgatga ccgcgttttt
    13561 caaggctacc gtcttaccca tcaaccaagt ccttggatgg gtgatttcag tcatatgctg
    13621 tttacgccga tcaatggaaa actacaggag aacacccttt tccatgctca aagttcttac
    13681 cgcccagaag aaagtatatt ttgcccgact catctgtcga tctgtcaatt acgttatggc
    13741 atctgttcta cattgatacc tagcatgtat ggcggaatct tatctattga ttacagcaaa
    13801 aatgacagcg gtttactttt atcctttccg ggacgccatc agctctttgt tatagatcct
    13861 tacacagtgg aaggaaaaat cacacatttt gctggttcag aagatcctga tttttctttt
    13921 tattttatat tgagatttga atatccttta acaattgatg agttagctgt ttccaacaaa
    13981 aatagcgact cgatcccgtt gtattttgaa cagacaaaaa aacaaactat ccgatttggg
    14041 acatctttta tcagctcgga acaagcagct tataacctgg aactagaaca aaaccaaagc
    14101 aaagagactt accttgctca cagtcaagaa caatggcagt cctattttga tcgtatacag
    14161 ctcacacacc atgatcaaca acaattgcgg acgttttatc ataatttata tcgggtgttt
    14221 ttatttccac aaacatttta tgaaattgat cctagtgggc aaaaaatcca ctatgatacg
    14281 actagtcgat ctataaaacc tggtgttctc tatacaaata atgggttttg ggatacgtat
    14341 aaaacggttt atcctcttta ttctttgatt gctgtagaaa aatacgaaga aatgctggaa
    14401 ggttttttga acagctatag agaaagtggc tatttgccaa aatggctgtc tcctgatgaa
    14461 cgtggactta tgcctgggac attgatcgat gcggtcattg cagatgctgc tgtaaaagat
    14521 atccgacgag acttgatgcc tgaatttcta acggcaatgg aaaaaggtgc tacggttcaa
    14581 agcaaacatc caaattatgg acgccaagga acagaagatt acttgacata tggctatgtt
    14641 cctaatcact accacgaatc agtcaatcac acattagact atgcttatag cgatttttgt
    14701 attagccaag ttgccaaggt actagaagaa gaggaaatga cgaagaaata tcagcagcaa
    14761 tcattgaact atcaaaatat ctttgactat gagtcaggat ttatgcgttc aaaagataaa
    14821 gatggcaagt tcagagaacc attttcagct aatcgttggg gacaagatta tgcagaagga
    14881 agtgcttggc aaagcagctt tgctgtttat cacgattttt caggactgat cggaaaatat
    14941 ggtggcagtg agagatataa agaaaaactc attgagctgt gcaatcagcc cccaacgttt
    15001 gacccaggag gatatggttt tgagatccac gaaatgagtg agatggccgc gatagaattt
    15061 ggacaattag ctatttcaaa ccagccaagt tttcactatc cttacttgtt cagttatata
    15121 ggacaacctg aaatggcaca gccactgctt aaacagttga tgactcagac cttcgacgat
    15181 tctccaatgg gttaccctgg agatgaggac aatggaagta tggccgcttg gtatatcttc
    15241 aatagtctgg gattttatcc tgtcacgcct ggaaccggtg aatatgttat cggtatgcca
    15301 ttaattgaca aggctgtttt gcttttgtca aatggaaagg aattgacgat tgaagcaacg
    15361 cctaatcggc cgcagcaaca atttatccat aaaatcaaac ggatggacag agaatatacg
    15421 aaattatatt ttacccatca agatttgctg aaaggcggca cgatctctta ccaattaggg
    15481 atcatccctc accctaagaa atatcaagca aaagatttgc ctttttcctt atcaaactat
    15541 aattaacaag aggttgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaagcaaa
    15601 aatagatcct catatttttc gtttggttgg tcttattacc gcagatgcaa gcttttgaac
    15661 accgtttatt gagaggttgt gaaatcagcg ttctgacctg agtattagag agacaaatgg
    15721 caaaatagtt cctcatattt tgccattttt tgagctaata ccgagggtca gctgattgaa
    15781 caccatttag tggagaggtc gtgaaaaagc tg
//
LOCUS       DADGHT010000066        15638 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.066, whole genome shotgun sequence.
ACCESSION   DADGHT010000066 DADGHT010000000
VERSION     DADGHT010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.066"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(32..907)
                     /locus_tag="JX887_001915"
     CDS             complement(32..907)
                     /locus_tag="JX887_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAX1257893.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            1055..1387
                     /locus_tag="JX887_001916"
     CDS             1055..1387
                     /locus_tag="JX887_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAX1257894.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            1499..2707
                     /locus_tag="JX887_001917"
     CDS             1499..2707
                     /locus_tag="JX887_001917"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAX1257895.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            2861..3316
                     /locus_tag="JX887_001918"
     CDS             2861..3316
                     /locus_tag="JX887_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257896.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            3678..3953
                     /locus_tag="JX887_001919"
     CDS             3678..3953
                     /locus_tag="JX887_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257897.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            3966..6044
                     /locus_tag="JX887_001920"
     CDS             3966..6044
                     /locus_tag="JX887_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAX1257898.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            6204..8090
                     /locus_tag="JX887_001921"
     CDS             6204..8090
                     /locus_tag="JX887_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAX1257899.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            8102..9049
                     /locus_tag="JX887_001922"
     CDS             8102..9049
                     /locus_tag="JX887_001922"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAX1257900.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            9069..9596
                     /locus_tag="JX887_001923"
     CDS             9069..9596
                     /locus_tag="JX887_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAX1257901.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(9659..10312)
                     /locus_tag="JX887_001924"
     CDS             complement(9659..10312)
                     /locus_tag="JX887_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAX1257902.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            10444..11286
                     /locus_tag="JX887_001925"
     CDS             10444..11286
                     /locus_tag="JX887_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAX1257903.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            11444..12340
                     /locus_tag="JX887_001926"
     CDS             11444..12340
                     /locus_tag="JX887_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAX1257904.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            12343..13056
                     /locus_tag="JX887_001927"
     CDS             12343..13056
                     /locus_tag="JX887_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAX1257905.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            13076..13594
                     /gene="msrA"
                     /locus_tag="JX887_001928"
     CDS             13076..13594
                     /gene="msrA"
                     /locus_tag="JX887_001928"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAX1257906.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            13591..13818
                     /locus_tag="JX887_001929"
     CDS             13591..13818
                     /locus_tag="JX887_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAX1257907.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            13970..14521
                     /gene="lepB"
                     /locus_tag="JX887_001930"
     CDS             13970..14521
                     /gene="lepB"
                     /locus_tag="JX887_001930"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAX1257908.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(14604..15146)
                     /locus_tag="JX887_001931"
     CDS             complement(14604..15146)
                     /locus_tag="JX887_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAX1257909.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(15383..15637)
                     /locus_tag="JX887_001932"
     CDS             complement(15383..15637)
                     /locus_tag="JX887_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAX1257910.1"
                     /translation="MLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQI
                     AKENGGTFHEVDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT         5409 a         2689 c         3171 g         4369 t
ORIGIN      
        1 ctttcctcat agcctatctt tgtctttttt cttatagttt tttcagtaat cttgtctgtg
       61 gcttcaaata agtaaagcct tgcccttcca cttcatgcac attgatgatt gaaaggaaag
      121 ctttttcgtc aatctcgtgg acgatcctct tagcttcagt taattcacta gagctaacga
      181 ccatatagat gatttttttt gaattaccag agaatgcgcc ttctccagaa aggaaagtca
      241 cacctctttg cagaccggtc atcagtagtg gtgcaatctc ttcgcttttg ttggagacga
      301 caagtagacc ttttgcagaa tatccgccat ctaagatcga atcaatcaca cgactgaaaa
      361 catacgaaac aatcaacgta tacatcatac gtttcaagtc gatataggtt aatgaagcaa
      421 gtaagacgat gatatcaaat gccaataggg aacgccccat agtgatgccg taattttgtt
      481 ctaaaatccg agcgataata tcactgccgc ctgttgttcc acccatgcgg tagacgatcc
      541 cgcttcctac acctgcaact aaacccgcaa gtagagaaac gatcagtaga tcatgctgta
      601 aattgatttc tagtggaacc ctttgccaga tccataaaaa gaatgacaaa gaaagtgtac
      661 ctagaacagt ataggccaag gaacgtttac cgaggatctt tcctcctagt aaaatcaatg
      721 ggatgttgat taataaagtc gtataagctg gatcaatacc aaataaagct cttaagatca
      781 aggtgatccc tgagactccc ccttctgcta aatgattagc gatgttcaag taaacaagac
      841 caaatgcata aatacttgtt cctataatga taaaaagaac ttcttttact gtttttcgtt
      901 tgaccatatg aattccagct ttcaattatg tattttcaca gaatttccat ttagaaattc
      961 cttcctaaat gtagcatgga aattcgattt tctcaattgc tcttatctag gatttgcgtt
     1021 aaagttttgg taagatagtt ttggagggaa aaagatggat aaaaagcgtt ctttatacag
     1081 tatgcagcag gaagtggatg aatatatcca gcaattcaag gtggggtatt tctctccatt
     1141 agctcagatg gctcgattaa ctgaagaagt aggtgaattg gcaagagaag tcaaccacac
     1201 ttatggagaa aaaagcaaaa aggcttctga accagttaac tcggtagcag aagaacttgg
     1261 tgatgtttta ttcgttacga tgatcatggc taattcattg aatatcgact taactgaagt
     1321 ttttgaaaaa aacatggaaa aattcaatca aagagaccat aatcgctttg agcgtaagga
     1381 cgagtaaaca agatgaagtg gtcctggcct tgaagactct gaaacggact tgtcaaacag
     1441 tcaccatgca actgagtctt tatctcagga caagaaacac gcaggaaagg ttggaaaaat
     1501 gaaattaaaa caattacctc tggaatacca aaaggcaatt ccagttctga aaaaattaga
     1561 gaatgcagga tatgaagctt attttgtagg tggaagtgtt cgtgatatct tgctgaacca
     1621 gccaatccat gatgtggata tcgcaacaag cgcatttcca gaagaaatca aacagctttt
     1681 tccaaaaacg atagatattg ggatcgaaca tggaactgtg ttggtattag aaaatgatga
     1741 acaatatgag atcaccacat ttcggacgga atcaacttat caggactacc gtagaccaga
     1801 tcatgtcgaa ttcgttcgtt cgttggcaga agatttgaaa agaagagatt ttacgatcaa
     1861 tgcgtttgct ttgaaagaag atggagaaat catcgatttg ttcgatggtc tgcaagatct
     1921 agaagaacag atcttgcgag ctgtaggcaa tcctcatgag cggttccatg aagatgcctt
     1981 acgaatgatg cgcgggttgc gttttgtcag tcaactaggg ttcaaattag aggaagaaac
     2041 cttctacgcc atcaaagaaa accacgagct attaggtaaa atatctgtag aacgtataaa
     2101 tgtggaattc atcaagatgc tcttgggaaa tgaacgggcc gcgggaatcc atgcatttat
     2161 tgaaacagag tgctacattt gctgtcccgg tttgaaagaa gaaggcgaag cacttttacg
     2221 ttttgctgaa ttaccatccg tcccattgaa agaagagagc caagcatggg cattattgat
     2281 cagccaactg gatctaaaag aaaatgagat tcgttccttt ttgaaatcgt ggaagtgttc
     2341 taaccaaatg attaaagacg ttcaagcact tgtccaagga ctacgacaac gagaaactgg
     2401 agctttggaa ccattcgaat tgtacttctt aggcaaaaaa catgcactgc aagtagaaga
     2461 attgatgatc tattttgacg aaacacctca gatggatgcc gtaggagaat cctatgatcg
     2521 tttacctatc aagtcattaa gcgaattagc agtagatggt aaaatcttgc tagaagaaac
     2581 tggaaaaaaa cctggtaagt gggttagtga agctttgcaa ttagctgaaa aagccgtcgt
     2641 agaacaaaga ataaaaaatg ataaaaaaca ggttttggat tttttatcga aagaaaaatt
     2701 gatttaaaaa acactagact gtatctgctc agctttgttg gctacttaaa gtgggcagat
     2761 acgtcattag aagaaaaaac ataagatgtg accacttaca taaatttgtg ctaaactgag
     2821 gtagtacaag aataaattac atcataaagg agtcttttta atgagtaaag aaatgacagc
     2881 gctaaaattt tattttagaa atggagaaac ctggacgatc aaccgccgtc atatcggcga
     2941 tctttggatc aaacaaatca caacaagttt tggacgaatc aatggcagtg aatttgttga
     3001 aatccatccg tgtgctggat ttaaaatcga aatcttccat gaaggggacg cagttgcgac
     3061 acatgatatc aacctaggcg gactggaaat gggcatgttt aatcgcgcat tgaaatacga
     3121 agatatcgag cgaatggaaa tcctttaccg aaatggcaca cctgatcttg tgtacttccc
     3181 atatctagat aaaggaacag aaggattaga caatcaatat caatcaacaa aaatcagcga
     3241 aaaaacaggt aacttgtata tcgtgatcaa tccagatcaa cgtgtagaag atgtatacgg
     3301 ggaatttttc gaataaatcg atttttacgc aaaaatgagg ctgtgaaaga gatgtgtctt
     3361 attactactg ataggctgtc tcttccacac cgtttattca gaataaggga ctgtgacaag
     3421 atttttgtcg cagccccatt tttttgttgt gataaaagaa caagaaaggc aggaatggga
     3481 aagtaaacat ccttttgtca gaaactttta tctttcttaa gttttacttg atatctgata
     3541 ctatttggaa tagaatgagg cgttgaaaaa tttatggaaa tttctaacta gcaataaacg
     3601 atgaaacaat gaaatatttt tcatccaaaa agaactttgc tataatgatg gaagtttgtg
     3661 tataggagat ctggaaaatg agagagagtt ttgaacaaca aaaaaaactg ttgcatgatc
     3721 gctatggcgc cctttcgatg gatgaccgcc gtcaaatact ttgtaagttg cgtaaaagaa
     3781 atatattgat gtatcgtcag ttggaacgtc tgaaacatga tctgcttcgt ttggagtcaa
     3841 aacgtgtaca gtgtgaatta gaggggaacc aaacacaggt tgaagtagtc gaaaccaaaa
     3901 ttttaaagaa aaaagaacaa tttttaaaaa tgcttacaca aaataaaaaa taaaggggat
     3961 ggacgatgga atttgctgag ttagttattg tatttgcagt aacgatcacc ttatcgaaca
     4021 tagctagccg cattttgcca atgattccag ctccactgat ccaaattttc cttggagtgg
     4081 tattaggtct gacagagtgg ggacaatcaa tcgattttga acctgaattg ttcttagtta
     4141 tgattattgc accattgtta tttagagaag gagaaaaagc agatatttct tcgattctca
     4201 aaaatttcgg gacaattttg ttcttggcat ttggaggagt cattttgacc cttgtcgggg
     4261 taggtgcgac gttatcattc ctgttgccaa gtgtcccact tgctgcctgc tttgcttttg
     4321 gagcagcgtt aggtccgaca gatgcggtag cagtcagttc tctttctgga cgagtgaata
     4381 tccctaaaaa ggcgatgcat attttggaag gagaaggtct tttgaatgat gcatctggtg
     4441 ttactgcctt ccagtttgct cttggtgcgc tgatcaccgg atctttttca gcagtaaacg
     4501 cggggatgag tctagtagtt tctagtattg ggggagcttt gatcggcttt ttgcttgtct
     4561 ggttcaaaca aaaaataatt catttgatcg aaaaagcatc agcacaagat gtcacagggt
     4621 atctgctgat cgaacttttg cttccttttc tagcctatgt attggcagag gcatttgatg
     4681 tatctggaat cattgctgca gtggcagcag gtattctcca agcttctggt tttaggaaaa
     4741 tctctgtgtt tgatgcagaa ttgtcgagct tgtcccacag tacatggaca actattgctt
     4801 ttacactgaa tgcattagta tttatatttt taggaatcga attgacgcaa gtgttctcgc
     4861 cagtatgggg agacggttta tatccaaacg gtcttttatt agcgattatc gtattaatct
     4921 ctgtcatgct ttttgtgatc agattcattt ctatcagtct tttttatgta ttcaaagatg
     4981 gcagtaaaaa gttcaaaaaa cagttgaacg agatcttgat cttaacattt ggcggtgtaa
     5041 agggaacagt cagtttggct acgattttta ttttgccatt ttcaatcaat aatatgatgt
     5101 tttaccagcg gtctttgctt ttgtttctga cggcgggtgt catcttagtg actttggtca
     5161 tagggatcat tgtcttgcct atgctgacgg aaacagagga agcgaaaagc acggatttga
     5221 atgctttgat gattttagaa gaggtcgttg aagttttgcg aaaagaaata aaggaaattg
     5281 atcgtaatac aaaagaattt ttagccactg aagcagtgat agaaaattat caagaacgga
     5341 tacgtgatct gtacttggaa gatttaaccg atgatgaaaa gcaagaagta caagaaatac
     5401 aagcactgat tttgtcgatc gaacgggatg gattggatga aagttatcgt tcgggcaagc
     5461 tttcttctaa tggttatcgt ttttactccc gttttctttc tcgattcgaa cattctatca
     5521 caagccagat tttgtctttt atcggctttt ggttcattgt tgtccgtagg ttaatgcgaa
     5581 tcgttctcca tccgaaaatg ttttggcaaa gaagatatgc tgatcgtcag acatttatta
     5641 gtgatgaaga tatccaagaa atcagagaga catatcaaaa aaatactcag ttgattattg
     5701 aaagtttaga taacttgact gatatttatg atgaaacgat ggttcaattt tttatccagc
     5761 aacgcaaact tgaaggaata aaaatgaact cggggaattt gatttcttcg tggatgatcc
     5821 agcaagatag tctgtttacg aaaaaaatgc taagaggtta ttatcttgaa agaaaaatca
     5881 ttgatgaata cgaagttgct gaaaaaatca cgacgttttc tgcgaacagc tatcgcagga
     5941 atatcaattt gttagaatct tatacgatga acaaaccatc tgataacttt tctttccgat
     6001 ttgcgtttcg agcaaagtca aaaaaaacga gtccaataaa ataaaaaggt aaaaattttc
     6061 aagttttata aaaaacaaaa catatcagaa caggatcgaa tcggtcctgt tctttttttg
     6121 agaacacaaa aagaacaaat accaaaaaaa ttttcctgaa gttcactatt tttatgatac
     6181 aatatccaag ataaggaggg aacatgttga aagaattaaa agtaactgac ctcaaaaaaa
     6241 cttatggtga aaaagatttg tttgaccaga tttctttttt ggtccacgaa aaagaccgta
     6301 tcgggttgat tgggacgaac gggacgggta aaacaagtct cttaaatatt attgccggta
     6361 tcgatagcag cgacggtgat cggcaaacag tgttttatcc aactgattac cgtattggtt
     6421 atctttctca agcagctgaa ttttccgatg aattaactgt tctccaagca gtctttcaag
     6481 gaaacagccc cttgatccaa actgttcgag catatgagga agcattgatc gaactagggg
     6541 aaaacggaga agaccctgat gtgcaaaaac gttatgctaa agcagaagaa caaatgaata
     6601 aagaagatgc ttggactaca gataccaacg caaagattat tttgcaaaaa ttaggaatca
     6661 gtgaattaga taaaaaaatc agtactttat caggtggtca gaaaaaacga gttagtctgg
     6721 cgcaagtgtt gattgatgaa cccgatttac tattactaga cgaaccaaca aaccatttag
     6781 attatgaagc gatcgagtgg ttggaaaact atttgaaaca ataccgtggc gcactattga
     6841 tggttaccca cgatcgttat tttctagata gagtagcaaa ccgaatcttc gaactttcat
     6901 ttggaaaatt atacgagtat aaaggaaatt atgaagctta cgtcttagaa aaagcagaac
     6961 gtgatcgtgt agaagtagaa caagaagaaa agcgcaagcg gctttataaa caggaattag
     7021 cttggatgag ggctggcgta caggcacgtg gcaccaagca gcaagcacgg atcaaccgtt
     7081 tcgaagatct aaaggagaac ttgtaccaag taaaccaaga agatgattta gagctgaacc
     7141 tagcgacaca acgtttaggg aaaaaagtac tggaaatcaa agatggcagt taccgtataa
     7201 atgaccaaac actgctagaa catttagatt tattgattca atctcgggaa agactaggta
     7261 ttactggtaa aaatggtgcg ggaaaatcga cattgcttaa tattctagct ggcagaattc
     7321 ccctggatag cggtacaatg tctatcggtg aaacggttca tcttgcgtat tatacacaag
     7381 aaaatgaaga aatggcacca gataaacgga tgattgctta cttacaagaa gctgctgaag
     7441 aagcaaaaac agcagatggc agtcaaatcg gagtagcaga attacttgaa cgatttttat
     7501 ttccaagatt tatgcatggg acactgatag gcaaactttc aggcggagaa aaacgccggt
     7561 tatttttgtt gaaactgctg attcagcaac ctaatgtttt attattggat gaaccgacca
     7621 atgatttgga catagcaaca ttgacgattt tggaagatta ttttagaagt tttccaggtg
     7681 ctgtgatcac tgtttcccat gaccgttatt tcttggacaa ggtagcagat aagttattag
     7741 tattccaagg aaacggaaaa caagaacttt attacggaaa catgtccagt tatttactga
     7801 agcaaaaaga gacccagcag cctgctgaaa aagcgaaacc aaaaatacag agcaaggaac
     7861 ctgctgaaaa gaagaaatta tcttacatgg aacaaaaaga atgggaaacg attgaagatg
     7921 agattgcaga acttgaagaa aaaatctcat tgctccaaga agagatgaat catcaaggag
     7981 ataatttcac tcgattacaa gaattgcaaa acgacgtatc tgaaacagaa gcacaacttg
     8041 aagaaaaaat ggcacggtgg gaatacttga gtgaatgggt agaagattag gaggaaaaag
     8101 gatggaacaa gcgtatcttg acttaggaag aaaattgttg gaagaagggc atcgtaaaga
     8161 agacagaaca ggcacaggca cattaagctt attcggatac caaatgcggt ttgatctgca
     8221 aaaagggttt cctttgttaa caacgaaacg agtacctttt ggattgatca aaagcgaatt
     8281 gctttggttt ttaaaaggag atacgaatat ccgctatcta ttacaaaata aaaaccatat
     8341 ttgggatgaa tgggcatttg aacgctacat caaaagtcca gactataatg gaccagatat
     8401 gactgatttt ggccatagat gtttgacaga tcctgaattc aatgaagaat ataaaaagca
     8461 gagcaagctt ttttgcgaga agatcctaac cgatgattcc tttgctgaaa catacggcga
     8521 tcttggacac atctacggct atcaatggcg tcactgggaa acaaaagacg gtggctttat
     8581 cgatcaaatc aaacaagtga tcgaagcaat caaaaagact cctgattcta gaagattgat
     8641 cgtttctgca tggaatccgg aagatgttcc tagcatggct ttgcctcctt gtcatacgat
     8701 gtttcaattt tatgttcaag agggacggct aagctgccaa ttgtatcaac gcagtgggga
     8761 tgtgtttcta ggcgttccgt tcaacattgc aagttatgcg ttgctgactc acctaattgc
     8821 acatgaaaca ggtttagcgg ttggcgaatt tgttcacaca ttaggagatg ctcatcttta
     8881 tatcaatcat atcgaacaaa tgaaagaaca attgagccga gaaatacgcg catttccgac
     8941 tttagttttg aatcaggaaa agcagtcagt atttgatttt gagatggaag atatccaatt
     9001 agaaggatat gacccacatc cggcgatcaa agctcctatc gctgtttaga atcagaaagg
     9061 atgagaaaat gttagctgca atttgggcac aggatgaaaa cggattgatt ggaaaagaag
     9121 accgtcttcc ttggcgtttg ccaaatgatc tgaaattctt caaacaaatg acagaagcaa
     9181 atacactagt gatgggacga aaaacattcg aagggatggg tagccgtccg ttgccgaatc
     9241 gtcagacgat tgttttgacg agagattctt cctataaagc agaaggcgtg catgtcatgc
     9301 atagtgtgga agacgtgctt gctctggaaa aagaaacaga cggtatcttt ttcatcgctg
     9361 gagggtcagc tgtttatcaa gaatttctgc cattttgtac gatattatac cgtacagtca
     9421 tccatcatgt attcgatgga gatgcttatt ttccacctgt tgactggtct gattggtcac
     9481 tgatcaatac tagtcaagga gaaatggatg aaaaaaatcg ttatccgcat caatttgaaa
     9541 cgtatcagcg taatgagaat cctgtaaaaa gcgggacagg cgaattgacg atataaaaaa
     9601 gctatggata gactagctgt tatttagagc tgtcccatcc atagctttat tttttttatt
     9661 aagtaaagaa taaaacagag aagtacataa aacctgcacc taacataaca aacaaatgcc
     9721 aaacaacatg catatagcgg atagaattca agctataaaa gaatgcgcct atcgtgtaag
     9781 aaagcccgcc tgctaccatc aaaataacac cagtcattcc aagagagtga taaagaggaa
     9841 cagcagccac gacacagagc caccccataa aaatatagat gatcgtagat acttttgata
     9901 ctctctcccg tttatgcaac gtcaacgctt tatatataat gccaagaatc gcaaacaacc
     9961 agattaatac aaataaagtc caacctagcc atcctcggat actcagcaaa caaaaaggag
    10021 tataacttcc tgcaatcaaa agaaaaatcg aactatgatc gaatacttgg aacacctttt
    10081 ttgcttttgt aaaaatcaat gaatgaaaca aagtagacgt taaaaataaa agaatcatca
    10141 tcgatccata gatagcataa gagacaatat ggagggagga atgcaagtgg gcacctttta
    10201 ctaaaagaac cactagtccc gcgatactca atccagtccc aattccatgg gtgactgcat
    10261 taaacacttc atttaatatt tcatacgttc gattaaattt cgttttttcc atgaaaacgg
    10321 ctcctttact aggtgtaatt aatgaaaaat cattatttgt ctgttatact aaaaatagaa
    10381 attgtcttac atgtagttta acatgaataa ggcatcttgt taaagaaaga gagagagaaa
    10441 ataatgacaa atgtaaaaat cgtaacagat tcttcatgta cgatggaaaa aaatgtacgc
    10501 gatgctttag gcattcgtgt catgccgcta tccatcatga tcgacggaac agtatatccc
    10561 gatgatgacc aactagacgg cgaaagattt atggaaatga tggcgaaagc aaaaaatctg
    10621 cccaaaacaa gccaaccacc aattggagaa ttcatctcga tgtatgatga gctaggagaa
    10681 gacggcagtg aagtgatttc gatccatatg acaaaaggct tgagtggaac agtagaagca
    10741 gcaagacaag ccagtaatct aacaaaaacg aaagtaacgg ttatcgacag tgataccact
    10801 gaccaaggat tatcttttca ggtaattcga gcagctgaat tagcaaaaga aggtaaaaca
    10861 gtagagaaaa tccttgaaga agtcaaaaaa gtacaagaca atacaaaatt atacatcgga
    10921 atatccacac tagataactt ggtaaaaggt ggaagaatca gccgaacaac tggtttgctg
    10981 tctagtgttt tgaacatacg cgtggtgatg aatttcgccc attctgaatt aatccctgta
    11041 actaaggggc gaggaaagaa aacgttcgat aaatggttta ataatttgaa aaatgaactg
    11101 aaagaattgc caaatgtgcg acaaatcggt atttcacatg cggatgcaaa agaattggcg
    11161 caagaattca aagagggttt gcaagaatta ttcccggaca tgcatatccc tgtactgcat
    11221 acgaatccgg ttatcgctac gcatactggt aaagacgcgt ttgcaatcat gtattatgta
    11281 gattagtcga aaagaggata agccctcagc ctgaaaggct tgcagcttat tctctttttc
    11341 tttataaaat taggaaaata attgttttct tttttcataa agactacctt tttgataaaa
    11401 tttttgataa cattagaacc aatcgaatac aagaggtgaa aaaatgaaat taacgaaacg
    11461 acatttgatc ctcgttttgt tcccattatt aattgcgatc atcatctatg caggtttagc
    11521 tgcttctata ccgaaagctg gcccactaat gaaaccagta actactgtga gagaagatcc
    11581 aaataaaaaa gaaaaacttc actacatagc tatcggagat tcgctgactg aaggagtagg
    11641 agatcaaacc aagcaaggag gattcgttcc ccttgtcgca aatgatctaa aagaccgtta
    11701 taatttgacc gcggttgaaa cagaaaacta tggtgtaaat ggtgaacgaa gtgaccagat
    11761 cttaaagcga gtaaaaacaa aagaagaaat tcgaaacaat atcaaaacag ctgattttat
    11821 cacactgact gttggcggta atgatttgat gaaagttatc caaaataatt tattcgggtt
    11881 aacggtcaat tcctttaaaa agccactgaa aaactatcag gaaaatgtca cagaactatt
    11941 ggaagaattt cgatccctca ataaaaccgc acctatttac attttaggca tctacaatcc
    12001 attttatttg aactttcctg agatcactga catgcagaca attgttaaca attggaacaa
    12061 aggaacagaa acggtgacaa aaaaaatgcc gaactgctac tttatcccaa tcaatgattt
    12121 gctttatcaa ggattgaatc aggaagtagg tgtcacagaa gaaggaacag atcaaacaac
    12181 tagcacgaca gaaaatctaa atggcatcaa aaataatgtg ctctatgaag aagatcattt
    12241 ccatccaaat aatttaggtt atcaattgat ggcaaatgca gtgagagatc agctgatcga
    12301 gacacaaaac caatggttag agaaggagga tgatcaataa acatgaaaac aagatctgac
    12361 gtatcttcaa acaaaacaaa gaaaacaaat tactggaaat tcgccttcct tatccttctt
    12421 ggggtagtac ttggttcgac cgtattttta ggcagccgta tttttgctaa tcgggaacca
    12481 gaactcccag aaataccagc tcttacggaa agacaaggag atcctgtctt aacgatcaat
    12541 tcaaataaag aaaaagtcaa tcaaatcatc agctttttcc ttagtgagta tcaaaaagat
    12601 agtgatattg aatataaatt ttatttggaa aatgaagcac tactcaatgg tactttcgaa
    12661 gtactaggtt ttcctatcga tttctattta tattttgatc cgtatgtgat ggaaaacgga
    12721 aatgtccaac taaaagctag aagtctttct atcggaacat tgagtttgcc aatcaaagat
    12781 gtgatgaata tgatcaagag aaactataaa ttaccagatt ggatcgaagt caatacagat
    12841 gatctgacta tcatgcttag gttggatcaa ttccgaatgc aaaacgggat gtatattaaa
    12901 gcagataaaa tcgacttagt aaatgatgac attcggttta gtctatattt gccaaaagat
    12961 acctctgatg cttcaaacaa ctcaaatacc aacaaaacta gcaccagcag tactgaaagc
    13021 aagacaaaag aaaataaaaa atcatcggat gagtagtatt agagggggaa tcataatgga
    13081 acgagcaata tttgcaggag gctgcttctg gtgtatgatc cagcctttcg acacgcttcc
    13141 tggtatccat acagtgatgt caggatatac tggagggcat gtaccagatc cgacttatga
    13201 acaagtaaaa agccaaacga ctggacatac agaagcagtg gagattatct atgatccaac
    13261 attgatttca tatgaacaat tagtagaact ttactggcag caaactgatc caactgacgc
    13321 tttcggacaa ttcgaggatc gcggtgacaa ttatcgcccg gtgatctttt atttgacaga
    13381 agaacagcgg atcattgctg aaaaaagtaa gaaacagtta gctgaaagtg gacgtttcga
    13441 acagccaatc gttacaaaaa tcgaaccagc ccaaccattt tatctagcag aagaagacca
    13501 tcaagagtat tataaaaagc atcctgaaaa ttttaaaaga aaccatgcac gccgggctgc
    13561 ctttatcgaa gaaaattgga ggaacgaagg gtgaatcgaa gcttttttca ttatttaatg
    13621 acactgcgag gcggtggcac acatgatgct ttatctgttt tcgctacaga agccggtaaa
    13681 gacatccaat ttcctaagca cagctctagc tacgaagaaa tttctaatta tctggaactg
    13741 aatgtcgact atttgccgtc catggatatc tttgacgaag catgggaaaa atatttagaa
    13801 aataatcatg acatataaga gatagttttg tactttatga tcaaaaaagt tttttgtcca
    13861 atagcctaat tgaaagaatt atttttattt cagctatcta gtcgcatttt tttgatattt
    13921 ttcttataat aaagaaagaa tgaaaaaaag agggatggat tgatagagat tgacaaaaaa
    13981 acaacgctat attaatcgct tctggcttgt attcaaatac ttacttgttt ctgtattcct
    14041 tgcgttcatg ttgcggggat ttttattcat cccggtacca gtggaaggca attcaatgga
    14101 aaacgtgttg aagcaaggtg atatggttgt gatggaaaaa ttttcggaga tcagacgatt
    14161 tgatattgtt gtttttcaat tagcagatgg cacgatttat atcaaacgag taatcggtct
    14221 tccaggagaa aatgtcagct accaaaatga tcaattgaag atcaatggga aagtagttaa
    14281 ggaaccttat ctaactaaaa acctgaaatc agatcatgca aatgcatcct atacgacgga
    14341 ctttacacta caagagctaa cgggacaatc caagcttccg gaagataatt attttgtact
    14401 tggagataat cgaagagttt caaaagatag tcgttcgttt ggcacgatca ataaaactga
    14461 tattctaggt aaagcaagat ttgtctatta tccacttgat gaaataaaat ggatccagtg
    14521 agaaacaata aagcgtgcag tctgttgaga ctgcacgctt tattgtttaa tccaaaatca
    14581 gtttactacc ttagtacgta aaatcaaaca gctcgtttaa acacttttct agcctctaaa
    14641 gttttgataa atgaataaac aaccattatt tgaataggga tttggatcat attcctgatg
    14701 aatctaccta gaaaaattac tttgaaatct gcaccaaaca aaacagacat cagccaagaa
    14761 ttgataaaaa ggctgactgg gatcataatc aataattggg cagcgatgac ggaaggcagg
    14821 tttatctttt tatgatataa aaataagcca ttaataaatc caccaaggaa agccgtgata
    14881 agaaaagcag cttgaaacgt tcctgaacca aatatcgtga aatttaaagt gttcgacaac
    14941 atttcaagca aaccagccca gatcggtcca tatagataac ccataagcgc catacttaaa
    15001 aatccgaatg tgatttgaaa ataagcagga ccaatcgcta tcttgtataa gatgacatca
    15061 agggctaata aaagagcaga ggtcgacaac aatcttgcat tcatttcggg caatctaaaa
    15121 acgtcttttg caatcaaagt gttcaaaata ttctctcctt tgtcagttaa taataaaagg
    15181 ataccataaa atcaccaatg tgtcatgaca cattggtgat ttacatacac tggcatctaa
    15241 caattaaaaa aagggtgaga agactgcttt tataaactgt aaaaaagaga ttgtacgaat
    15301 aaaaaaaata gaggcggaga atacttatcg tatcatccgc ctttgttttt ttgttataaa
    15361 aaacgtcaga ttagttatct gcttacatct tcatccatac gggttctaat gtatttccgt
    15421 ctagatcttg gacttctaat gaaaacattt cttcttcagg cattcccata tctacttcgt
    15481 ggaaagtacc accattttct tttgcaattt gagcaaattt ttttacttca tccgcatttt
    15541 caacactaaa cgaaatcaaa gcaccacttg tttttttatt atcagctatt tctttatctt
    15601 ttataaattt tttataaaaa tcatgagaga gaagcatt
//
LOCUS       DADGHT010000067        15439 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.067, whole genome shotgun sequence.
ACCESSION   DADGHT010000067 DADGHT010000000
VERSION     DADGHT010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15439
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.067"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(66..296)
                     /locus_tag="JX887_001933"
     CDS             complement(66..296)
                     /locus_tag="JX887_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257911.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(732..1298)
                     /locus_tag="JX887_001934"
     CDS             complement(732..1298)
                     /locus_tag="JX887_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAX1257912.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1298..2254)
                     /locus_tag="JX887_001935"
     CDS             complement(1298..2254)
                     /locus_tag="JX887_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAX1257913.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2254..2910)
                     /locus_tag="JX887_001936"
     CDS             complement(2254..2910)
                     /locus_tag="JX887_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAX1257914.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3280..5298
                     /locus_tag="JX887_001937"
     CDS             3280..5298
                     /locus_tag="JX887_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAX1257915.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            5725..8139
                     /locus_tag="JX887_001938"
     CDS             5725..8139
                     /locus_tag="JX887_001938"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAX1257916.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8487..10040
                     /locus_tag="JX887_001939"
     CDS             8487..10040
                     /locus_tag="JX887_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAX1257917.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10421..12205)
                     /locus_tag="JX887_001940"
     CDS             complement(10421..12205)
                     /locus_tag="JX887_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1257918.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12220..13941)
                     /locus_tag="JX887_001941"
     CDS             complement(12220..13941)
                     /locus_tag="JX887_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1257919.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            14041..14802
                     /locus_tag="JX887_001942"
     CDS             14041..14802
                     /locus_tag="JX887_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAX1257920.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         5034 a         2813 c         3016 g         4576 t
ORIGIN      
        1 tttgacaaat ctattcgaag gatcaaattt aaaccataat tgcgtctcat taaaaagcat
       61 aaccattact ccgatctatt tttaaactta gtctctacct ctaatatata tcgagttttt
      121 attttgcctt cagagaatac tgtttctttt tttgcagtta caggttgttt attttcggaa
      181 aaagctaata tagctaaaat tgaaacatcc atctggaatt tatctttttt actgctttga
      241 tcataaaagt ctgcatattc atcactgata ttttttctaa taaattcttc catcataaaa
      301 atcacctcaa aacgattata cgaacttacg ttcttgttgt aaagcgatat ttgaggggca
      361 aaaaaggggc ataatttgac tgatattaag ttagctattg atatatgaat gacatacaaa
      421 aatataaaat cttttaaaaa tgcttatata tcaatgtttt tgccattctt ttatatatct
      481 gttatatgtc aaaaaaatgt gttcaatttc aatttgtatt tgaataaaga ggttgtgaaa
      541 aagctgtcct gcatcaagta ataagaacag ccaatcaaaa acagcttctc atgtttttga
      601 tttggttgga cttattaccg cagatataag cttttgagca ccgtgaataa agaggttatg
      661 aaatcaacgc tctaacctga gtattagaga aaaaaacgca aaacatatca tttatgtttt
      721 gcgtttttta tttatctttt tttctcaata caatataaaa taggcggctg gttcttttgg
      781 ttgataaacc gataattcag cacattatat gtttcctgtg gcagtttgga acaaaaagaa
      841 tcaaccatat ccagttcttt ttctccacct tcatgaccat agtagacgac aaggatcaat
      901 cgtccgcgag gcacaagtcg tttcaatatt tcttccatag ctgtgcgtgt agtctctggc
      961 atagtgatga ttgctttatc actttttggg agatacccta gattgaaaat ccctgctttg
     1021 agattttgtt gttcagctat cacttctcct aacgtttcgt ggccttgtag aaacaatgag
     1081 acacgttctt ctaactgacg ctgttctagc ctttcacgag tagcatcgat tgcttgttgc
     1141 tggatatcaa aactatagac atgaccagtt tttccgatgt gttctgctag aaaaaccgta
     1201 tcgtggccat tgcccatcgt tgcatctacg acgtgatccc ctggttgcaa gatttcttgc
     1261 agtaatgtat ggctgaaatg caaagcagtt tgcaacatca gacgctcacc tttttccgta
     1321 catcatattt tccttggaag ctatctctgc gaagaagttc ttcatcaatt gcattcaaga
     1381 cttcccattt tttcaagctc cacattggtc caatcaagga atcccacggc gcatcccctg
     1441 tcaaacgatg gatgatgatc tcttttggta tcatttccag ctggtcgcaa atgacattga
     1501 catagtcagg acggctcatt aattgaaggc gaccttcatg atagtcccgc aacattctcg
     1561 ttttgcgcat cagatgcatc aaatggagct tgattccttg gatatctgaa tctaaaatgg
     1621 tgcgtctgac attttctttc atcatttcta aactttcgcc tggtaatccg ttgatcaaat
     1681 gcgtacaaac acggatatta tgtttgcgta atttagccac gccatctaaa taagtttgat
     1741 aatcatgtgc tcggttgatc agttttgaag tttcttcaaa agttgtttgc aatccaagtt
     1801 ctacccataa atacatccgc tcgttcagtt cagcaaggta atcaactact tcatctggca
     1861 gacaatccgg tcgtgtaccg actgataatc ctacgacacc tggtaaattg actacttgct
     1921 caaatcgttc tttgattatt tcaactggcg catgggtgtt tgtaaaattt tggaaataaa
     1981 cgatgtattg ttggacatga ggccattttt gatgcatcat gtcgatttct ttctggaatt
     2041 ggattggaag agggtcttca ggtgcaacga tcatgtctcc cgaaccagat acactgcaaa
     2101 aagtacaacc gccatgggca acagtcccat ctcgattcgg acagtcaaat cctccatcga
     2161 tcggcacctt gaaaattttc ccgccaaact catttcgtaa agcgtaattc caagaatgat
     2221 atcttttatt tccttctgaa taaggaaaag tcattaaaag tccttctttc tgtaagagtt
     2281 atctatttgt tttctttttt ctctatacac tggataagtc aggcacagcc aagaaagact
     2341 gagtaagtag ccgccgatga tatcagtagg aaaatgaacg cccagataaa tgcggcttat
     2401 cccgacactt actataataa acatcatcag caattgaagc aatgtgcgta aggttctttt
     2461 ttgaacaaaa gctggaagca gaaatagtaa agaaccgtaa agaatcatac tgcctgctgc
     2521 atgtccacta gggaaactgt aacttgtttc aactactaag tgcgccaatg aaggacgctc
     2581 tcgcatgaaa aatagtttga tcaccgggtt gatgattcca gcaattacaa taaatccaga
     2641 aacgaaccaa aatgtttctg cccttttttt cttataccac atccataaag ccgcacaagc
     2701 aaataaaatg atgacggtaa gaggattacc gaatttagtc ataaagagtt ggtagctgtt
     2761 cagatcagga taagaagctc tgacaatgcc tgtaaaccac tgatcgaaac cagaaagcca
     2821 cgacagatgg aactttacga tccagcccaa aatgaaaaac aggacaagaa agaagctacc
     2881 agccacctga aatgatgttt tatatttcat acaattcctc ctttgaagca atgacttatt
     2941 atagcatttt tggtccagcg aaaaaaacgg taaagagata aaaccaatgt atgattcctc
     3001 tttgaataac caatattctt ataaaaaaaa taactgtaat cggaaagaca ttttttggta
     3061 atgcaaatga aatgttaggg aaataaaatc agtgtttttc gaaatccttt taaacaagaa
     3121 cgtagacgta ggaagaactt gaaaatgaac agaagttgtt cattacggta aattacaata
     3181 tgattacaaa aaacaacaaa gctcttaaat aacttttaat aaatattaag agaagttata
     3241 attattaata atagataaat tgaagttgga ggatagaaga tggaaaacat tgcaagaaaa
     3301 gaacggagac gtttagaaca gaccaaacgt tttcgaaaag caaaacgagg ggcagcaatc
     3361 gtgggaactg cgatggtagg ctgttctgtc gctgccccat tagtacagcc ggttcctgtt
     3421 caagcggatg aaacacctgt tcagttcggc gcaagaatca atacagcggc atttatcaca
     3481 gaaattgcta cttatgctca accaatcgct caagccaacg atctatatgc atcagtgatg
     3541 atcgcacaag cagttgtaga aagcggttgg ggcagtagtg cgttatctca agcaccttat
     3601 tataatcttt ttgggataaa aggcagctat caaggacaaa ccgtctacat ggatacgctt
     3661 gaatttttaa ataatcaatg ggtaaataaa aaggagcctt tccgacaata tccttctttt
     3721 gctgaatctt tcaatgacaa tgcctatgta cttagaaata cttcatttgg caacggttat
     3781 tactatgccg gtacttggaa gagcaacacg aaatcctata cagatgcgac agcttgtttg
     3841 acagggcgtt atgcgactga tcctggttac gcaggcaaat taaataatat catcgcaact
     3901 tacggattga cccaatatga tacaccagct agcggaaacg caggcggtgg agcgactaca
     3961 ggtggcaata atactggaag tgcaggtagt actggcggtt caagcaattc tggtaataca
     4021 aactcaggtt cagcaacttc gaccacttat actgtccaat ctggtgattc tgtttgggga
     4081 atctcaaata aattcggtat cacaatggat caattgatcc aatggaacaa catccaaaac
     4141 aatttcattt atccaggaca aaaactgaca atcaaaggta gccaggaaaa tggctcttcg
     4201 acgaataatt ccggtaacaa taccaactct tcaggaaatg ctggtacatc aaacggagga
     4261 caaacaactg gtgcgaaata cactgttcaa tctggtgatt ctgtttggaa gatctcaaat
     4321 gatcacggaa ttacgatggc tcaattgatt gaatggaaca atatcaagaa caatttcgtt
     4381 tatccaggac aacagctaat cgtatcaaat ggcggttctt ctaatgctgg agcaaatact
     4441 ggctcaaata ctgggaatac aagtggctct agttcgtcca gctcaagttc ttctaataca
     4501 gcttcaggaa cgaaatatac agttaaagcc ggagactctg tttggagcgt ctcaaataaa
     4561 tacggaatta cgatggctca gctaatccaa tggaacaata tccaaaataa ctttatctac
     4621 ccaggacaac aactgactgt ttcaaacagt ggatcaacaa acagcacgtc aggtaataca
     4681 ggttcgtcaa ccaatacaaa taacagcagt tcagttaata ctggcagcag ttcgtctcaa
     4741 ggcacttata ccgtgaaagc aggtgaatct gtttggagcg tggcaaataa aaacggcatc
     4801 acgatggatc agttaatcga atggaataat atcaaaaaca acttcattta tccaggacag
     4861 caattgatcg ttaaaggtgg aacttcggca aatacaaata caggttcaac tacttctgca
     4921 gcgaaaccaa atacaccgaa tacgtctgct acgacaagta catcatccac tggtaatacg
     4981 atgtataccg tgaaagcggg cgagtcagtt tggagcgtag cgaacaaaca tcatatcacg
     5041 atggatcagt taatcgaatg gaataatatc aaaaataatt tcatctatcc aggacagcaa
     5101 gtgattgtga agaaaggttc atctcaatca acaaaccaac aatcagttac tggttcgaaa
     5161 acctatactg tgaaatctgg agaatctgtt tggagtgttg ctgacagtca tggaattaca
     5221 atggctcaac taatcgaatg gaacaatatt aagaacaact ttatttatcc aggtcaaacg
     5281 ttgattgtag ctaaataaaa tagctgttcg aagaaataac gattgaattc cacaaaaata
     5341 tttgttacta taaggctact taaatatgac aacacttgaa aaggaagtag taaaaagact
     5401 gaagtttcag agagcgcatg gctggtgaga atgtgcacgg atgcttttga actcgccttt
     5461 gagttgccct tgctgaatac ccgagtaagc aagcggcggt gacggccgtt acaacgttcg
     5521 aggccttttc actaaggtaa aattaggtgg taccgcgtag attacgtcct ataaaaagag
     5581 caatcttttt ataggatttt tttatttctt ttgtgaagtt tgagaaaaca aagcaaaagg
     5641 aaataaaaat aaacagattc tgccggtttt ttcgttatat ttataataga aacaagtgtt
     5701 ttcaatagaa caggaggaca gcaaatgagt tacaatcata aagaaattga gaaaaaatgg
     5761 caaaaatact gggcaaaaac gaatactttc aacacccatg atgatcctga aaagccaaaa
     5821 ttttacgcac tggatatgtt tccctatcca tccggtcaag ggctacatgt agggcatcct
     5881 gaaggttata cggcaacgga tatcctttca cgtgtgaaaa gaagtcaagg atacaacgtg
     5941 ctgcatccaa tggggtggga tgcattcggt ctgcctgctg aacaatatgc gctagataca
     6001 ggaaacgatc cagctgagtt tacccaaaaa aatatcgaaa cattccgacg ccaaatcaat
     6061 tctttaggat ttagttatga ctggaatcgc gaagtgaata caactgatcc ggagtattat
     6121 aaatggacac aatggatctt tacgaagctt tatgaaaaag gtctagctta tgaagcagaa
     6181 gtagcggtaa actgggtacc tgaattagga acagttattt caaatgaaga agtgatcgat
     6241 gggaaaagtg aacgtggtgg ctatgatgta gtcagaaaac caatgcgcca atggatgctg
     6301 aaaatcactg cttatgctga tcgcttattg gatgatctag aattagttga ttggccagaa
     6361 agcattaaag aaatgcaaag aaattggatc ggtcgttcag taggagcaaa tattgaattt
     6421 aaagtggctg gtacggataa atcctatacc gtatttacga cacgaccaga tactctattc
     6481 ggtgcaactt actcggttct tgcacctgaa ctagatcttg ttagagaaat tacgacccct
     6541 gaacaaaaag ctgctgtaga agcttatatc gaagagacag ctaaaaaatc agatctaaag
     6601 agaacggatc ttgcaaaaga aaaaacagga gtatttactg gtgcttatgc aatcaatcca
     6661 gttaatggca aggaaatccc aatctggatc gccgattatg tattatcttc atacggcaca
     6721 ggagccatca tggctgttcc agcacatgat gaacgtgact ttgaattcgc tcaaactttc
     6781 ggactagaaa ttcttccagt tatcgaaggt ggagatgttg aaaaagctgc ttacacagaa
     6841 gatggtacgc acatcaactc tgaatttcta gacggcatga acaaacaaga agcaatcgat
     6901 aaaatgaatg aatggctaga agaaaatggc gtagggaaaa aagaagtcag ctatcgctta
     6961 cgtgactggc tattctcccg tcaacgttac tggggtgaac caatcccaat catccattgg
     7021 gaggacggaa cagtcacagc tgtcccagaa gaagagctac cattacggtt gcctaagaca
     7081 aaaaacatca agccaagcgg tactggagaa tctccattag caaatatcga ggagtgggtc
     7141 aatgtcgttg atcctgtaac aggtaaaaaa ggccgtcgcg aaacgaatac aatgccacaa
     7201 tgggcaggaa gctcatggta ttacctgcgt tatatcgacc ctcataacaa aaaagaacta
     7261 gcagattatg aaaagttgaa gcgttggcta ccagttgaca tctacattgg tggagcagaa
     7321 catgcggtac ttcatttact atatgcacga ttctggcata aattcttata cgatatcggt
     7381 gttgttccta caaaagaacc attccaaaaa ctatacaatc aaggaatgat cttaggcgaa
     7441 aacaacgaaa aaatgtcaaa atctcgtggt aatgtagtca atcctgatga tgtggtcgaa
     7501 acttacggtg cagatacact gcgcatgtac gaaatgttca tggggccatt agatgcttcg
     7561 attgcttgga gcgaaaatgg cttagaagga agccgtaaat tcttggatcg tgtatggcgt
     7621 ttgatcgttg atgagaacaa taaaatgcgt gaccgtatca ctacattgaa tgatggcaag
     7681 cttgataaag tgtatcatca aacagtgaaa aaagtgacag aagactatga aaatcttcat
     7741 ttcaatacag caatctccca attgatggtc tttatcaatg aagcctataa agtggacgct
     7801 ctgccttatg aatatatcga aggatttgtt caactactcg caccgattgc tcctcacatg
     7861 ggtgaagaac tatgggcaat ccttggaaat gatggtggta tttcttacgc accatggcca
     7921 acatacgatg aagcagcact tgttgaagac gaagtagaag ttgttttcca agtaaacggt
     7981 aaagttcgtg cgaaaagcaa tgttccccga gacttaggaa aagatgagct agaaaaagca
     8041 gcattagcca atgaaatagt gcaagaatat attgaaggca aaacagtcag aaaagttatt
     8101 gcggtaccaa acaagttagt caatatcgtt gctaattaat tggctctttg tcaataagga
     8161 ctgatgagtt gtgcaaaatc aaatctgggc cagaatgaac ttcattctgt ctcagatttt
     8221 ttgttatttc aaattgatta attgattgat caaaaaggtt ttgattttca tgttctcaaa
     8281 cacgttcaat gtctttttct tctgaatggt cttgtaagag atctctgtaa tcatcaaatt
     8341 tttgtctatt aatcttagta ttttttgatg tataaactac ctgaaattga gagtacatac
     8401 caaattcata aattttttat tagtgggact agtgattgta tggattttga cgcataatga
     8461 atgaagtatg agaaaaggag agacaaatgg atcaagaact atttattatc gaagtattat
     8521 cagctaaaca aaaaattatc gagaaagcga aaaaaagagc gaaaagaata atgttcaagc
     8581 ttttaagctt agtatttttc tctggtttgc tttttttcgg agctgtatcg ttcctatatc
     8641 gccatatgag tgcagtagtc cgttcagctg aagggatgca aaaattaaat aatttgtatc
     8701 acttttcgtg gggagttggc ggaataacaa ttgttgtgct tattgttttt cttctactta
     8761 tttggctccg ttaccatcaa ttgtcgcgtc atttcgatca atggcttagt caaagagcac
     8821 aacagttttt acataataaa ccaacttctc aagatgatga ctatctttat tttgagaaga
     8881 cttcgacgag tcaagctttt cggatacaaa aaagtgattg ccagttattg ctgagatcac
     8941 ttgatgattt acctatctac ttaggcgaaa gcaaatcaaa attcggaatg aacacattcc
     9001 atattttttt actagaaaac gaacccagat gggaaaaaag ccagtcttcg cctggtggat
     9061 acctgacaac taagatgagt acattagtca ctggtttttt cctcattctt ttagctggaa
     9121 caatctatta tgggagatac actcagccaa aaatgtcttc tcatataaat gctgcttctc
     9181 acatgacaat gaactcaact aacgatacgc atatacaaaa gacaaatgaa gggttgttag
     9241 ctgatcctaa gcaaaaggta aatttgacaa cacaaaagat aaatgatctc aaacttgata
     9301 cagagacgca ctctctctat atgacaacag atagtggtgc taattgggta tttgtgccga
     9361 ttgattcgca atggttgcgt tttggcgaat acaccctgac aacggggctg attcctgaag
     9421 gttattggat ggacaacaca tatgatattt ccgccgattt ctcatggttt atctattctt
     9481 ctggggatga tgtacgtctg ctgacttcaa gagataatgg taaaacatgg caaacgtcta
     9541 ttatcaccca atcagttcag ccgatacgtt atcgaaaagc ggtattttat ggcaacgatg
     9601 gtctatttat ctgtacatca gccagtggga tgtctgcaga aactttgtac atttacacta
     9661 ctatggatgg cggaatcact tggataaaaa gtggaagtac aatgatcaat cagccagtac
     9721 aaaatgtcag cttcgttaca acttctttag gttttgtttc gacacgtgaa agtttgtttt
     9781 atacaaacaa cggaggacgc tcattcaaag aatcagttct gtcgattccg gaaaactatc
     9841 agacaggggg gatagatctt tttcaatcac caaatgaagt tactcaaata agcgcgaata
     9901 cgttagagac aaaattttat ttgttgaaaa aaggaccaat cgatgcaggg aaaatgtttg
     9961 cctgcctctt ccgttcaact gataacgggg aaacatggca attcgttcag caactatcgc
    10021 aagtagaaca aggagattaa agaagagaga ttgtgagcct gacgttcagc accgagtcac
    10081 aagaaacaaa ttcaaaaaac agcttctcat atttgttgaa tagtgtaact cgtgattcgg
    10141 agttgacaag agcaacaaga agcgattttg aagtatagct tctcgtattt tacaagatcg
    10201 tgtcttattg ccgataggtt gtctcttgaa caccgtttat tcgtaaaaag ggattgtgac
    10261 aagtcttttg tcactactta ccgaacgaaa ctgaaggagc tatccaaaaa gtatcattag
    10321 tattattctt tgtgtttcta gtggcaccac tagtacattt aaaaaagcta tcgatcatgg
    10381 actaatcata catgatcgat agctttttag ataatgtttg ttacgctatc tgaaattgac
    10441 tattataaag actggcataa agcgttggtg attggagtag ttcagaatgt gttccttttt
    10501 cgacgatatc gccattcttc attacaagga tcatgtctgc attttcaatc gttgacaaac
    10561 ggtgtgcaat cacaaaactt gtcctatctt ttgtcacagc ttccattgct tgctgaatca
    10621 atgcttctgt tcgtgtatct acgctagaag ttgcttcatc taaaataacg acaggaggat
    10681 tcgctagaat gactcgagca attgtcaata attgttgctg tccttgagat aacgtgccgt
    10741 tttcgctaga aatgatcgta tcatatccgt ctggcagtgt tcgaataaag tgatcacatt
    10801 gtgcgatttc agccgcttcg ataatttgtt ctcttgtggc atccattttc ccgtaggcga
    10861 tattatcagc taccgttcct tcaaacagcc aggtattttg taaaaccatc ccaaaagaac
    10921 gacgtagttc tccacgtgaa agcttggtaa tatcaagacc gtcgaattcg atctttcctt
    10981 tattcagttc ataaaaacgc atcagcagat tgactaaagt cgtttttcct gcaccagttg
    11041 gaccaacgat cgctaccgtt tgttttggct ttactgaaaa atcgacttga ttcatcaata
    11101 ttttatctga tgtgtaacca aactgtacat ttttgaaagc tatttttcct ttcggttgtt
    11161 ctaaaagtct tgcatctgga aggtctggaa tttcatctgt ttcatctaat atctcaaata
    11221 tcctatcgat tgctgccatt gcggattgga tcgagttgat cacataagaa gcggtagaaa
    11281 ttggttcaga aatctgattg atgtactgaa gataagcttg taagaagccg atcgtcacac
    11341 cacctgatag aacaagcata gcaccgaata ccgcacttat gatgaaggcg agttgattaa
    11401 tgaaacgaat ggccggatag atagcacagt tcataaattg agcacgttta aaagcgttgt
    11461 attgcttttt atttacttcg tgtatagcag cttctgcatg agcttgctga ttgaatgttt
    11521 tgaccactag attaccagct aagatttctt ccattcgatt atttaaaaca cccagttcat
    11581 actgattctg ttcagaaatc tgtttgtttt tgttcgcaat cttagttgta acaattgaac
    11641 tgccaacgat cagcaataag acgagcaaag taagcttgct ttcgatataa aacagcatca
    11701 gaccagcagc agctattgtt acgacagaag taaaaaattg attgatacct gtcaataaca
    11761 cttgagaaag ttgattgaga ccggtagttg tccgactaat gatgtcacct acttgatgat
    11821 tgtcaaaaaa cgacatcggt aatgttttga atttttttgt gatttctttt cgcaccctca
    11881 atgtgatctt ttcgcttaac gctgccattg tccgttcctg aataaatgaa gtgatgctgc
    11941 ttaagactga acagccgatc agcaataaga cagggaacaa caatgcttgt ttgatatcac
    12001 tgaaagaaag ctgtccaata cctgtttttc ttatttctga taagagatca tcgatcccga
    12061 ttcccatgat caagggcatg gctacgacta ataggttccc gaataaactg catagaaaca
    12121 atccgtaaaa atatttatgt tcaggtttga tcattttcca aaaacgtatc aaagcacgcg
    12181 tgttcaacgt ttttttcttt tccatcgtat cccttctttc tatattcctt gtgattttgc
    12241 aaactcctga taagtttggc aattagacag tagttcttca tgagtacctt gtccaacgat
    12301 ttttccttca tctaaaacaa tgatgttatc tgcttgttgg attgtactga ggcgttgagc
    12361 aacaatcacg agagttttct ccgacatgtg tttatgaagg gctgctctta atgctgcatc
    12421 tgttttatag tctaaagcgg agaaactatc atcgaataca tagatctctg ctggtttgat
    12481 caacgctcga gcaatacata tccgctgttt ctggccccct gaataattag aaccgccttg
    12541 agcaacaaag ctgtccaatc cgtcaggaag ggtgtccact agttcttcta attgagcgat
    12601 cttgatcgct ttagacaact cttctgttga ggcatattca tttcccatct gcaagttgct
    12661 taaaattgtc ccgctgaata agaaagcctt ctgagggaca taactgatgt gggagcggat
    12721 ctgttcttga gtcatttgag taagaggaat accaccaagg gttacttttc ctatcgtagg
    12781 gtcactaagt ctcaagagaa gtttcgccaa actacttttt ccagatccgg tcccgccaac
    12841 gatcgctgtt gtttttcctt taggtattgt gaaatcaata tcttctagaa ctggatcaga
    12901 gatttcagta tatttaaatg tgacatgttc aaaagcagct gcatttgtct gatcaaaggt
    12961 tggttcagct actgttttga tcgtctcttc ctcaatttcg atctctgctt gcagtatttc
    13021 ttctatccgt cgtaatgagg caaacgattt agggataatg accaatacca tagctgcgat
    13081 catcaagtaa gcaagtgtca gcatagagta ttcgactaca gcagtcacga caccgatttg
    13141 taatgctcct tctgctacaa gatttccgcc aaaccacaaa atagaagcat aaacgattcc
    13201 catgagcaaa aaagcaattg gagtgaccca agcaaatatt cggttcactt tgatcatttg
    13261 attagcatag tcagcaaagc tcttattcgt tcgcttttct tcatatgatt gattatcaaa
    13321 ggcacggatc atattaatcc cagtaaagaa ttctctcaat gtgatggtga tccgatccat
    13381 ttttggctgg atactcaaag ataaaggtgc ccctcgtttc atcagtcgat aaacaatcca
    13441 tacataaaaa acaacagaga tcaatgtaac ccatgttagt aatagagaat aacgaaacat
    13501 catgagaatg gtgaaaacgc aaataaccgg tgctggtaag atcatttggc aaaataaaac
    13561 aatcatttgc tggacattat cgacatcatt cgtcattctt gtcaaaagag atccagaact
    13621 aaaacgactg atatccttca ttgacagctg ttggaattta cggaaatatt tctcccgcgt
    13681 ttggaatcca aacctagcgg aagccaatgc tgaaaagtaa ctagaggcaa ctgcagcgat
    13741 tgttcctaga aacgctacaa gcagcatttc aactccaatt ttttttataa ctgaggcttc
    13801 gccacttgct atacctgtgt cgatcagctt tgctactaat tttggtacac ctaatgtacc
    13861 ggcgatttct aaacagatca tcacaaaggt aaggagagcg agtcctttgt ttttctgtaa
    13921 gaatgttttt aagatagaca tattattcct ccttttttcc tgatactttt cgattctata
    13981 ccttcaagta acttgaaggt caatagaaaa aagaataaac tgaaaaagag gtgagaaaaa
    14041 atgaaaaaaa tgtatacgat tggccaagta tcggaactat ttgatttgcc aaaatcaacg
    14101 atccgctatt gggatgaaca aggattaatc cgttcaagta gacaagaaga gaatgattat
    14161 cgattgtttg atatcgatga tatttttatg ctttatgata tcgtttttta tagaaaatta
    14221 gatataccga tcaaacagat gaagaattta tatggaaaaa cattgacgga gttatatgag
    14281 acacttgatg aaacagaaag aagaatccat aaagaactgg tggtgatgaa acaaaaacaa
    14341 aaagagataa gggagcaaaa aaaacagttg aaattgatga tcgatacaaa cgaggaagaa
    14401 tttcctgtag aagagatccc ttttgactgt atgatctcaa cggagtttga agatattgtg
    14461 gaaatcaaaa aatttctacc taactattca agctttggga tgatgagtat gccagcttcc
    14521 agttcacaga cgatgtatgg attttttatc gaccctagtg aagtacattt atttactcaa
    14581 gacgtgattt gggagaaaaa agatacggct gtttatcgtc gattcttatt gaaatccgag
    14641 atgaaccatg cggaacgtaa taatatttta gaaatcagag aaagaatgta tgaaaaagga
    14701 tggaaaacag gagaagtgat cggccagtat ctattgacga atacggatga aaacaatatc
    14761 agaactgaat attatcatgc atggatagaa atgaaaaaat aggaaatatg tgtttaagat
    14821 aactcgaaaa tgatggttgt tttagttata aagaaaaatt ttctggttcg attacgggtt
    14881 taatgtgggg gattattagt cgtggataga tagaatttta gttttttaga ggaaatatgt
    14941 ctttaaaaat ggaatggttg caattcttag cgatatatac gatgtaattg tcctcttaaa
    15001 aaagtatgga aaaataattg tattgggtgt tatgtataat tcatggtgaa ctgagactaa
    15061 tgagaagaaa aattcatatt gttatgagtg agattgtatc agatgagaat gataaattaa
    15121 ataggtgcat aaaagcatta cacttaaaat acattgttgc ttacattatt acaatatgtt
    15181 aataaggcaa aaataaatag atggattgaa taaacatatt ttttaatcaa atagtcccta
    15241 ctgtgacttt cctcagctat cggtgatact accgatagca tttttttgct tataaaataa
    15301 ttataagtat ttagagattt ttcttctaac attcttcaaa caagaaaaat cacaaaggtt
    15361 attgttattt ttatatattc tttttaagaa tgattgtttt tttatagaaa ttttaaaaaa
    15421 taaaacacgt tattgatgg
//
LOCUS       DADGHT010000068        15252 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.068, whole genome shotgun sequence.
ACCESSION   DADGHT010000068 DADGHT010000000
VERSION     DADGHT010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.068"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            333..947
                     /gene="gmk"
                     /locus_tag="JX887_001943"
     CDS             333..947
                     /gene="gmk"
                     /locus_tag="JX887_001943"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAX1257921.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            952..1257
                     /locus_tag="JX887_001944"
     CDS             952..1257
                     /locus_tag="JX887_001944"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAX1257922.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            1510..3918
                     /gene="priA"
                     /locus_tag="JX887_001945"
     CDS             1510..3918
                     /gene="priA"
                     /locus_tag="JX887_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAX1257923.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            3933..4424
                     /gene="def"
                     /locus_tag="JX887_001946"
     CDS             3933..4424
                     /gene="def"
                     /locus_tag="JX887_001946"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAX1257924.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            4417..5355
                     /locus_tag="JX887_001947"
     CDS             4417..5355
                     /locus_tag="JX887_001947"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAX1257925.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            5355..6713
                     /gene="rsmB"
                     /locus_tag="JX887_001948"
     CDS             5355..6713
                     /gene="rsmB"
                     /locus_tag="JX887_001948"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAX1257926.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            6726..7466
                     /locus_tag="JX887_001949"
     CDS             6726..7466
                     /locus_tag="JX887_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAX1257927.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            7463..9532
                     /gene="pknB"
                     /locus_tag="JX887_001950"
     CDS             7463..9532
                     /gene="pknB"
                     /locus_tag="JX887_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAX1257928.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            9697..10596
                     /gene="rsgA"
                     /locus_tag="JX887_001951"
     CDS             9697..10596
                     /gene="rsgA"
                     /locus_tag="JX887_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAX1257929.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            10609..11259
                     /locus_tag="JX887_001952"
     CDS             10609..11259
                     /locus_tag="JX887_001952"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAX1257930.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            11260..11898
                     /locus_tag="JX887_001953"
     CDS             11260..11898
                     /locus_tag="JX887_001953"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAX1257931.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            12053..12907
                     /gene="mreC"
                     /locus_tag="JX887_001954"
     CDS             12053..12907
                     /gene="mreC"
                     /locus_tag="JX887_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAX1257932.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            12911..13420
                     /gene="mreD"
                     /locus_tag="JX887_001955"
     CDS             12911..13420
                     /gene="mreD"
                     /locus_tag="JX887_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAX1257933.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            13675..15249
                     /locus_tag="JX887_001956"
     CDS             13675..15249
                     /locus_tag="JX887_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257934.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
BASE COUNT         5113 a         2864 c         3318 g         3957 t
ORIGIN      
        1 gtattaagcc aaatttatgc aaaaatgtga gaaactattt tcacaaaatt tttcttcata
       61 ctcgaaacta atcggcttct tcacgacctc ttatacacgg cgttcaaaag cttgcatctg
      121 cgataataac cccaaccaaa cgaaaaacat gagaagctgt ttatgtttgg ctgttcttat
      181 tacttgatgc aggacagctt ttttacgacc tcttggtaca gggtagcttt tttaccaatt
      241 tctagctata attaaagata accttgaaag ttgcagaaaa aaagtgcaaa ataaacgata
      301 agtacaaaaa gactagttga aaggacgtcg tcatgtcaga gcgtggatta ttaatcgtgt
      361 tgtctggtcc atccggtgta ggaaaaggca cagtacgaaa agcaattttt gagagtgagg
      421 ataatgattt tcagtattcg atctcaatga ctacccgtaa aatgcgtgaa ggggaggtcg
      481 aaggcgttga ttatttcttc cgaagcaaag aagagtttga atcaatgatc gaagctggag
      541 agatgctgga atacgcagaa tatgtcggga attattatgg aactcctttg tcatatatca
      601 acaagacatt ggatgaagga aaagatgttt tcttggagat tgaagtccaa ggagcaaaac
      661 aagtcaaaga aaaagtgccc gatggtgtat tcatcttttt gactccgcca gatttagcgg
      721 aattaaaatc acggatcgta ggccgaggaa cagatgcaga tgaagtaatc gaagaacgaa
      781 tgaaagttgc aaaagaagaa atcgaaatga tggctcttta cgactatgct gttgtaaatg
      841 atgaagtgcc gctagcagtt gaacgaatca aaaacattat tgccagtgaa cattttcgag
      901 tagatcgcgt aatcggtaaa tatattaaaa tgttaaagga gatgtagtct tatgatgtta
      961 aaaccttcaa ttgactcact attagatcgt gtaaattcaa aatattctct agtgatttta
     1021 gcaagtaaac gcgcgcatga attggatgca agtgcacagc ctactctaga ttcttttgat
     1081 tcagtaaaaa gcgtcggtca agctttagaa gaaatcgatg caggaaatgt agtcaatgat
     1141 ccacatcctg aattaaaacg tgaacgtttg aagatggaag aagaggaacg tcaagcacaa
     1201 aaagagcgtg aacaacacga attggaatca cgtatccgtg aagagcaaaa aatgtaataa
     1261 agaaaaatag agcgaacatc taaaaagaaa agcaaaccca gctgtttcct tttcaaacat
     1321 tcgccactta ttgtctggta gaaaaggctg tgtctgaact ttttgacaca gttctttttt
     1381 ttcttatctg ctgttaattt tttgttagga tttggcagaa gataagacaa atccatcgat
     1441 ctctagtaaa ataggcaagg aactttttgt cgcttgataa gaaaagacaa aaaaaggagg
     1501 aaacgaacca tgacattaac agctgaagtc attgtggacg tacctactat gcagaccgat
     1561 cagccattca cttatttggt tccctctgaa atggaaacag ctttgcaagt cgggatgcga
     1621 gtagaagtcc cttttggtaa tggcaatcgt catgtccaag gatttgttat ggctatccaa
     1681 aaatcagaag aatcagctaa tccatctttg aaggcagtta ttcgtttgct agaccttgct
     1741 ccggtggtca atgaagaatt actttcatta gctgattata tgaaaaaaat tacttacgca
     1801 ttcaaaatca cttgtctaca aacgatgctt ccgagtgtga tgaaagcaga atatgataaa
     1861 ttgatctatc ctttggcaga cacaccagaa gttcaggtat tgtttgatca gcgagaagtg
     1921 atttcctgga aggaagcaga agaagaaggc agcctttctc aattgattcg ctggcgccaa
     1981 gagcaattag tagatatcaa atatgaagtc catacacgaa ataaagtaaa aacgattcgt
     2041 ttggtccgtt ctttgttaac tgaaaagcaa atcgaagaag aatgggcaaa attacggcaa
     2101 aatgccaaga aacaaaaaga acttcttttg tgtttatctg aactgagcca agaagaacca
     2161 attgcttatt tcaaaaataa aggaatcagt actgctgtct tgaatcaagg aaaagaaaag
     2221 ggctggctgg agtttataga atcagaacgt tatcgcgacc cttataaaga ccgagtattt
     2281 gaccaaacga cggcattgga actgaatgca gaacaaaaaa atgctgtcga acaaatcatc
     2341 acagcaggtc agcagcaaaa agatcaggtc tttttgctgg agggaatcac tggcagcggg
     2401 aaaacagaag tatatcttca ggcaatcgct gatgttttgt cagaaaataa aacggctatt
     2461 atgttagtgc ctgaaatcgc attgactccg caaatggtcg agcgattcaa aggacgcttc
     2521 ggagaatcag ttgcggtctt acatagcgga ctttcccaag gtgaaaaata tgatgaatgg
     2581 cgcaagattg agcgggaaga agcgcaagta gtagtaggcg cacgatctgc tatttttgcc
     2641 ccgctgaaaa atatcgggct gatcattatc gatgaagaac atgaatcaag ttacaaacaa
     2701 gatgagacac cgcgttatca tgcgagagat ctagcaattt ggcgcagtaa atatcatcat
     2761 tgcccaatag ttctaggaag cgcgacgccc tctttagaat caagagcacg agctcaaaaa
     2821 ggcgtttatc agttattgca gttaaaccac cgagccaaag cagctgcaca gcttccagct
     2881 attgagatcg tagatatgcg tgaagagttt cagaatcatc ggacctctac tttttctgct
     2941 aatttgcagg aaaaaataca aaatcgatta gacaaaaaag aacaaactgt cctactgctc
     3001 aatcgtcgag gatattcgtc ttttgtgatg tgtagggact gtggatttgt tcttccatgt
     3061 cctaattgcg atatctctct tacactgcat atggatacac gttcaatgcg ctgccattat
     3121 tgcggacatg aagaacctat tcccaatcgc tgtcctaatt gtggcggcaa taaaatccgc
     3181 tactatggaa caggtactca aaaagtagaa gaggaactcc gagaacttta tccgcaagct
     3241 aggattttgc gtatggatgt agataccact cgaagaaaag gggcacacga acagatttta
     3301 caaaaattcg gtgcaaaaga agcagatata ttattaggga cacaaatgat tgctaaaggt
     3361 ttggactttc cagaagtgac attagttggg gtgttgaatg ctgatacctc cctgaattta
     3421 ccggattttc gttctagtga gcatacattc caattgctta cccaagtttc aggacgagca
     3481 gggcgagcgg aaaaagcagg cgaagtcgtg atccaaacat tcaatcctca acattacgcc
     3541 atagaattag ctaaaaaaca aaattatgag cagttttatc agcaggaaat gcatgtacgg
     3601 catcgtggag gctatcctcc ttattacttt actgtgaaaa taaccgccag ccatcctgaa
     3661 gaacaagtag cggcaaagaa aatctttcag attgccaatc agctaaaaga agtgttaagc
     3721 cctcaaagct tgctattagg gccaacgccc agcatgattt tgagagtgaa aaaccgatat
     3781 tattatcaac taatcatcaa atataaacat gaaccgaatc ttcctcatgt tttggatgaa
     3841 attttgaatg gaagccagaa agaacagcga caaggtcttt ttgtggcaat tgacaacgaa
     3901 ccattaaact ttatttaaga aagggccaaa ttatgcgcta tcctatattg atccacccta
     3961 atgataaatt aaaaagaact gctcagccaa tcgatgtaat cacggacgag acaatcgctt
     4021 tattagacaa tttatatgag acaatgattg cgaatgacgg aatagggatc gctgctcctc
     4081 aagtaggaca aaacaagaga attgctgtga tcgaagtaga tgaaggcgag aaatttgaac
     4141 tgattaaccc agaaatcatc gaagcaaaag gtgaaagcct tgacgtagaa ggttgtctca
     4201 gtattccgca tgtctatgga acggtcaagc gagcagatga agtgaccgtg cgttattatg
     4261 atcgagacgg agaagagata gaagtgacgg cttttggcta tttagcccgt gccttccagc
     4321 atgaaatcga tcacttagac ggtatcttgt tcattgagaa aatgatacag cagatcccgg
     4381 aagaagaact tgaagaatat atggaggaac atcttgatga ctaagctagt atttatgggc
     4441 acacctgctt tttctgtgcc gattcttgaa gggctgatag aatcaggtta cgagatccag
     4501 gcagtggtaa cacagcccga ccgtccagtt gggcggaaac gagtaattac gccgacaccg
     4561 gtaaaagaag cggctctgaa gcacggtatc cgtgtgctgc agccagagaa aatctccggt
     4621 tcgccagaaa tggaagaaat cattgaattg gtgcctgatg tgatcgtcac tgcggcattt
     4681 ggccaattct tgcctgaaaa gttattgcaa gtaccaaaat taggggcaat caatgtccat
     4741 gcttctttac ttcctaaata tcggggaggt gcgcctgttc attatgccat catgaatggg
     4801 gagaaagaaa ctggtgtaac gatcatggaa atgatcaaaa aaatggatgc aggcggaatc
     4861 tatgcgcaag aaagcatacc aatcactaaa caagatgatg tagggacgat gtttgaaaag
     4921 cttagccttt taggaagaaa gctattgcta gaaacattgc ccaatatttt ggatggacaa
     4981 aaaccagtac ctcaagacga gtcagaagca actttttcgc caaacatcac acgggaacaa
     5041 gaagcaatcg attggcataa aactgcagaa gaaattgaca accaagtacg cggaatgcgt
     5101 ccttggccaa ttgcattcac gacctatgag ggcatacgct ggaaattatt atcggttgaa
     5161 gtattggcag aaactacaga caaagcacct ggtacgatca tccggaaaga caaaaaaaat
     5221 ctatggattg cttgcggtaa acagaccgtc ttagccatca atgaattaca gccagctggt
     5281 aaaggaaaac aggccgtaca tgatttcctt aacggaagcg gtcagcaagt tcagattggt
     5341 cagcaggtga aataatgaaa aaaatcccta aaaaaatgaa aaaatcagta cgatatatgg
     5401 cattactgac attagagcga gtgaacaagg gtggcgccta ctcgaatctt ttgttgaatg
     5461 agatgatcaa acaaagcgag ctaaatcaaa aagatgtggg tttatttaca gaattgatct
     5521 atggtacgat tagccatcag cgactattgg aattttacgt tgcaccattg atcgctaaag
     5581 caaaaaaagt ggatgactgg gtcaagacgc ttctttatct ttctgtatac caattagaat
     5641 ttttagataa agtccctgca catgctattt taaacgaggc ggtcgaaatc gcaaaagtaa
     5701 aaggaaatcc tgggacaggg aaatttgtaa atggtgtctt gaggaattat cagcgtcaag
     5761 gagcaccaga tctgcaaggc attgctgatc ctatcgaaag actttctgtc aaaatcagcc
     5821 tgcctctatg gatgacgaaa cgactggtgg atcaaatcgg atacgaagaa actgaaaagc
     5881 tcggtttatc gctatatcag cctagccatg ctagtgcccg agtagataca cgccgacttt
     5941 ccagagatca ggccatcact gttttgcaag aagaagagat cacagctgaa aaaagccaag
     6001 tcagtccata cggtatagta gcgaaaaaag ggcatttagc ttctagctca ttgttccacg
     6061 atggcgtcat gacgatccaa gatgaaagtt cgatgcttgt agcgccgtct atgcaaatcg
     6121 agcctgaaca tcatgtctta gatgcctgtg cagcacccgg aggtaagacg acgcatattg
     6181 cttctttttt agatccgtca tgcggtggag aagtggtcgc tttagatgta cacgaacaca
     6241 aagtcaaact cattgaagat aatgcagcac gtctaggtgt ctcttctgct gtctacgctc
     6301 aaaagatgga tgctagagaa gtcagtaaac agttcgaagc agagcagttt gatcggattt
     6361 tagtagacgc gccttgttca ggtcttgggc tgcttcggcg aaaaccagat attcgttata
     6421 aaaaacagcc ggatgaatta gcgaatttac caaaaatcca attggaaatt ttagaaagct
     6481 gcgcaccaac tttaaagtct tccggtattc tgacttatag cacttgtacg atcttaaaag
     6541 aagaaaacca agacgttgtt tctgctttct tggaaagaca ccctgatttt gagaggattg
     6601 atgttttgac caatcctatg ctacaatcat caatcgaaga gaaaatgttg actttgtatc
     6661 cgcatcagtt ttacacagat ggatttttca tttgttgttt gcgcaaaaag taatgaggtg
     6721 aaaaaatgca gattgaatat caatcagatg taggaagacg acgtaacaca aatcaagact
     6781 atgccagtgt atttaccagc cgttcaggtc tcaagcttgc tgtattagca gacgggatgg
     6841 gtggtcatcg tgccggagac attgccagtc agatggcggt aacgaatcta ggcgaagctt
     6901 gggaaaaaca agaagctgtt gacgatgaaa aaatcgccca atggttcatt caatcgattc
     6961 aagaagaaaa tatgctgatt tatcagcgtg gacaagaaca gccggaatat aacggtatgg
     7021 gaacaacaat cgtagcggcc gctctgtcag atgactggtt cacgattgcc aatgttgggg
     7081 atagcagagc ttatttgatt cgtgaagata aaatcatgca attgacggag gatcattctt
     7141 tagtcaatga actagtcaaa tcaggagaaa tcagcgaaga aatggcagtg aaccatccaa
     7201 ggaaaaatat tttaacacgt tctgtcggca tgcctggaac agtcgaagta gatgtttcta
     7261 ctcatctttg gcaactaaaa gatcgactgc tgttatgttc agatggcttg acgaacatgc
     7321 tgtctgaaga agaaatagga acgatcatca atcaagaagg cccattgtct cataaagtaa
     7381 ctgagctgat tgatcgtgcc aatgaagcag gcggagcgga taatatcacc gttcttctta
     7441 tcgaatataa ggaggacagt gtatgatcga gttgggcaaa aaattaaatg gccgttatca
     7501 aatcactgga aatatcggta gcggtggtat ggcaaatgta tttttggcgc acgatttaat
     7561 cttggatcgt gatgtagcag ttaaagtctt acgatttgac tttcaaaatg accagactgc
     7621 gattcgacga tttcagagag aagctttagc agcaacagaa ctcgttcatc caaacattgt
     7681 tagtgtttac gatgttggtg aagaagacaa catgcagtat ctggtgatgg aatacgtcaa
     7741 aggaatggac ttgaaacgat atatccaaac acattatcct gttccttatg aaacagcagt
     7801 aaatattatg cagcagatcc tttctgctat ttctttagct cataaccatc aaatcatcca
     7861 ccgagatttg aaaccccaaa acgtactgat cgataatgaa ggtgttgtaa aaatcacgga
     7921 tttcgggatt gctatcgctt tatctgaaac atcgatcacg cagacgaata cgatgctggg
     7981 atctgttcat tatctgtccc ctgagcaggc cagaggaagt atggcaacga agcagtcaga
     8041 tatttatgct ttagggatca tcctttatga gatgttgacg ggtagcgtac cgtttgatgg
     8101 tgaatctgct gtaacaattg ctttaaaaca ttttcaagat gatcttccat ctataaaagc
     8161 acttgatcca aatgtgccac aagcactgga aaacgtgatt ttacgggcaa cggctaaaga
     8221 acctgcagac cgttataagt cagccgagga aatgtctgat gatctttcta cagtattatc
     8281 accagctcgt gcaaacgaag aaaaatggca gcctcatgtg atggataatg aaacaaaagt
     8341 tatcacaccc cttacggaag atgcaccaat gcctgattca ttcaaatcta tgcctctgcc
     8401 aaaagacaag ccagaaaacg aaaccttgcc agaggaggaa gaagttctgc ctgatcctaa
     8461 aaagaaagga cagaaaaaat ggtggctgat cctattagct attcttgctg ttttaggaat
     8521 cggaacagct gtattctttg cttctggcgg gcgaggagaa gttgttgttc ctgatgtttc
     8581 tgatctttct gaagcttctg ctagagaaac actcgcaaaa gcgaaattag aagtagcaac
     8641 aaaaacagaa gaaattgcag atgacaaaat cgaagaaggt aatgtagtga agacagaccc
     8701 ggcagcggga acgacagtca agcaaaaacg cgaagtcact ctgtatatta gtagcggcac
     8761 gaaaaaaatc aaattagatg attacagtgg taaaagttat gaagatgccg aagcaagttt
     8821 gaaagaatta gggttttctg ctgacttgat tcaaaaagaa gaggaattca gttcagaggt
     8881 agaaagcgga atgatcattt cgcaatctcc atcagaagat acagaagtcg atcctaaaac
     8941 agacacgatt actttcacag tcagcaaagg accagaaaca gtgactttga gtagtcatgt
     9001 aggagaaaac tacgaaactg ttcgtaattg gcttgttaca caaggattca atatcaataa
     9061 tattagtgct acttatgact atagcgacac tgtaccatca ggttcgatca tcagtcagga
     9121 tccagcctcg ggtgaagttg tagcagaaga aacttacatc aattttgtcg taagccaagg
     9181 aacagagcct aaattgaatg atatctccgg ctatacaaaa agcgaagcac aaagttattt
     9241 agctagtgtc ggtgcagaat atatcgggca tgagacttcc gaatattcaa acacggtgga
     9301 taaagataaa gtgattcgta cagtaccagg ggcaggaacg acaattacca aaggaatggt
     9361 tgtgaacgta atttactcta aaggaccaga tccagcgtct tctagttctg aaaaagactc
     9421 ttcagacagt tctagcagct caagtagctc cagtagcaca agcaactctt caaaagaaga
     9481 atcttccagc tccacaagtt catcagctag cacctcagaa agttcaaaat aagtgctgaa
     9541 taaaatatat cagaagggaa tgcgacattg atttgttgca ttctcttttt tgtgtttcta
     9601 tctcttttga tcaattttca agccatatac tttgagaagt ttgcatggaa taacacctac
     9661 tttcctcttc gtatggtaaa ataaacaaaa acggaggtgg cacttatcaa aggacaaatc
     9721 agaaaagcaa tcagcggttt ttactatgta tacgcaaacg gagagaccta tcaaacaaga
     9781 ggaagaggaa atttccggaa tcggaaaatc acgccgcttg tcggagatca ggtgatcttt
     9841 gagagtgaaa atcaaacaga cggctatctt ctggaaatct tgccgagaaa aaatcaatta
     9901 gttcgcccac cagtcacaaa tgttgatctt ggaatcattg tcacaagtat cgtagagcct
     9961 gcattttctt ataatctact tgaccgcttt ctagttacct tggaatacga gtcgatcgaa
    10021 ccgattattt ttttgacaaa gaccgacttg tcagacgacc cagaaaaaat cgaagagatc
    10081 aagcaaacct atactaaaat aggctatccg gtgattgtac ccaatcatac gggtgatacg
    10141 acagaactga tccgttactt cccagaacgg ctatcggtct ttatgggtca gtctggagca
    10201 ggaaaatcga cgctactgaa tcaaatatca ccggaactga atttagcaac aggagagatt
    10261 tctgatgcac ttggaagagg acggcataca acacgtcatg tggaactgat tcctatctat
    10321 ggcgggttag tagcagatac accaggattt agctcgattg actttttgac aattgaagca
    10381 ggagaactgc cgagacaatt tcctgaattt gtagaagctt ctgtccattg caaatttaga
    10441 gagtgcatgc atgctaaaga acctggctgc gaagtaaaac atagagtaga aacaggtggt
    10501 atcgcacaga cacgttacga caattatttg caattcttac aagaaatcga aaaaagaaaa
    10561 ccaatgtatg caaaaaaaga aggtaaacga aaataggagg aaacaagaat gaagatagca
    10621 ccatccattt tgagtgcaga ttttgccaat ttacaaagag acattgagtt agtggaaaaa
    10681 ggaggcgcag attacatcca cgtagatgta atggatggcc aatttgtccc aaatatcaca
    10741 ttagggccaa atattgttca ggcaatccgt cctgttacta aattaccgtt agacgtccat
    10801 ctgatgatcg ttgatccaga aaactacatt ccagcatttg caaaagctgg agcagatatc
    10861 attactgtcc acgtcgaagc aactcctcat attcatcggg cacttcaaat gacaaaaagc
    10921 ttaggagtta aagctggagt agttatcaat ccaggaacac cagtctccat gatcaaacat
    10981 gttttgcctt tggctgatca agtactagtc atgactgtca atcctgggtt cggcggacaa
    11041 agctttattg aagaaacagt agaaaaaatt acggaactcg ctgatctacg tagagagaac
    11101 aattggactt atgcaatcga agtagatggc ggaatcgttc cagaaacagc aaaaatctgt
    11161 aaagatgcag gggcggatgt cttcgttgca ggatcatata tctatggagc cgaaaatcca
    11221 gtcggacaaa tcgaacgatt aaaagaggca ttagactaaa tgaaaatttt attagctgct
    11281 ggaggtaatc cgcaaaactg gccgcagtct ctgctgtcca aatacgatgc ctatgtcggg
    11341 atagaccgtg gtgcgctgta cctgcttcaa gcaggctacc cagtagatct ggcagtgggc
    11401 gattttgatt cattgtcgaa cgaagagcag aaggaagtat ttgcaaaagc caaagagtat
    11461 acccgttccc ctgcagaaaa agacgataca gatacacagt taggtatctt aaaaacattt
    11521 gaacgttacc cgcaagcgga agtcactttg attggagcta cgggcggaag attggatcat
    11581 cttttagcca atctctggtt aggtatggaa cctcgcttca aaccctttgc ccatcagctt
    11641 attatcagag attgtcaaaa ttatttgtct tattatttgc ctggagagca tatagtaaga
    11701 cagataccag atatgaagta tttagcttat tgctgcttga ctcccgtctc gaatcttaca
    11761 ttaaaaggca gcaagtatgt attggaaaat aaagaagtag aatatccgac atcttatgca
    11821 agtaacgaat ttctttcaga taccgcagaa ttttcttttt cagatggtat gattgcagtt
    11881 attcaaagca aagattgatc cataaacaaa taaaaaaatt tgtctttcag gctaaaaatg
    11941 acagaatcta ttatttgcta aaaaaaagct taagaggagc aacttacctt ttgtttcacg
    12001 gcatttagtg ataaaattga acacaagagt ctaattaatt cgaggtgtct ttgtgaagaa
    12061 gttcaatcct aataaaaata ttattattac cttggttatt gttatcatcg tggtgacgat
    12121 actaagtgtg accgctgcgc agcgagcgaa tgaaggaaag cccaatttct tccaatccat
    12181 cgttaatgac agtgttgcaa tggttgataa aacaatctct gccccagtac ggtgggtacg
    12241 aaatggagta gattctgtcc ataatctttt ttcaacttat gccgaaaatg agcggctaaa
    12301 agaaaaaatc gatagctatg atgacgtttc acagcaaaac aagaattacg agagagaaat
    12361 cgaagcgttg aaaaaagaac ttgagttgaa tcagacgctg actagttacg aaaaagtaac
    12421 ggcaaatgtc attactcgtt cgcctgacag ttggcaggac atgctgatcg tagacaaggg
    12481 ttctaaagac ggtatcgaag caaatatggc agtcatgtcg caaaaaggat tgattggccg
    12541 agtgatcgag gtcaatacgg cttcgtctaa aatcgaatta ctgtcatcct ctaatgaaag
    12601 ctccaatcat tttccagtac gggtatcttc ggctaatggc gaagcgtttg gtttgcttaa
    12661 aaactatgat gaaaagctcc atgccttagt ggtgacccaa ttaactggtg atacggatat
    12721 caaagaaggg gatgttgtcc agacatccgg tcttggaggg aattctccag ctaacttgcc
    12781 gatcggtacg gttattaaaa cgaaaccaga tagttatggg ctggatcggg aagtttatgt
    12841 gaaaccttat gcagaaatgt atgacgtgtc agttgtgacg attgtccaac ggctagcgga
    12901 ggattagtcc atgttgaaga aagaaacaat gaagtactat ctgccaatcg ttttgttctt
    12961 tttgatgttg atagatggtc atttaacaag aatgctaggg gagtggtcga aaggcaccta
    13021 tatgtcaaat gcccactttc tgatattggc attattatgt tgcagtatgg cgtttgaaaa
    13081 acgttattta ctgattacca cgattgttct cggggctatc tatgacgctt actatattgg
    13141 cgttatcggt atctatgcag tagctctccc tttaattgta tggttgatgt atgtaatgaa
    13201 agacgttatc catgtcaaca tctttactga atttttcagt atgatcatct ttgtcacggg
    13261 ttatgaattg tttacgatgg tggtccagtt gatttttaaa ttagcagtag taaataacac
    13321 gtattttatt acaaggtttt taggacctac actgctgttg aacatgatta tatttgtatt
    13381 attcattttt ccctttaaga aattattcag tgatgaataa tttctttttt tatttttagg
    13441 tcgaaagcga aaaagaatcg ttgttatctt aagaaatgct agacttaacg cggctttttc
    13501 atgatcattt tctgaaacga acagttttgt catttttaaa agttgttttg aaacattttt
    13561 gtaacataac tattatatcg ttgacacact gctatggtac aatttttata tcgttaagaa
    13621 agacttaaat atatttagat atttattaaa ttaagccagt cggaggaatg aagagtgaaa
    13681 aagagtttaa tatcagcagt aatggtatgt tcaatgacct tgactgccgt agcatcaccg
    13741 atcgctgccg cggcggacga ttttgattct cagatacaac agcaagatca aaagattgca
    13801 gacttgaaaa atcaacaagc agatgcacaa tcacaaatcg atgccttaga aagccaagtt
    13861 tctgaaatca acacacaagc acaagaccta ttagcaaaac aagatacatt gcgtcaagaa
    13921 tctgcacaat tagtaaaaga cattgcagat ttacaagaac gtattgaaaa acgtgaagat
    13981 acaatccaaa aacaagcacg cgaagcacaa gtaagcaaca caagctcaaa ctacatcgat
    14041 gctgtattga atgctgattc attagcagat gctattggac gcgttcaagc aatgacaacg
    14101 atggtaaaag caaacaacga cttgatggaa caacaaaaac aagataaaaa agctgtagaa
    14161 gacaaaaaag ctgaaaacga tgctaaacta aaagaattag ctgaaaacca agctgctttg
    14221 gaatctcaaa aaggcgatct tttatctaaa caagctgatt tgaacgtact gaaaacttca
    14281 ttagctgctg aacaagcaac tgctgaagac aagaaagctg acttgaaccg tcaaaaagca
    14341 gaagctgaag cagagcaagc tcgtattcgt gaacaacaac gtctagcaga acaagctcgt
    14401 caacaagctg cacaagaaaa agctgaaaaa gaagcacgcg aacaagcaga ggctgaagca
    14461 caagctactc aagcttcatc tactgcacaa agctcagcaa cagaagaatc atcagctaca
    14521 caatcttcaa tgactgaaga atcatcatca gctacacaat cttcagcaac agaagaatca
    14581 acaacacctg aatcttcaac agaagaatca acagcgcctg aatcttcagc aacagaagaa
    14641 tcaacaacag cgcctgaatc ttcagcaaca gaagaatcaa caacagtgcc tgaatcttca
    14701 gcaacagaag aatcaacaac agtgcctgaa tcttcaacaa cagaagaatc aacaacacct
    14761 gcgcctacaa caccatcaac agatcaaagt gttgatacag gaaacggcac aggaagtagt
    14821 actccggctc caacgccaac accaacacct gaacaaccaa aacctgtaac acctgctcca
    14881 gctccttctg gaagtgtgaa tggtgcagca atcgtagcag aagcttacaa atatattggt
    14941 actccatatg tttggggcgg taaagatcca agtggctttg actgctcagg gttcacacgc
    15001 tatgtttaca tgcaagtaac tggtcgtgac atcggtggtt ggacagttcc tcaagaatca
    15061 gctggaacaa aaatttcagt ttctcaagca aaagctggag acttgttatt ctgggggtca
    15121 caaggcggaa cttaccacgt agcgattgct ttaggcggag gacaatatat ccatgctcct
    15181 caaccaggcg aaagcgtaaa agttggttca gttcaatggt ttgcccctga ctttgctgtc
    15241 agcatgtaag aa
//
LOCUS       DADGHT010000069        15228 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.069, whole genome shotgun sequence.
ACCESSION   DADGHT010000069 DADGHT010000000
VERSION     DADGHT010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15228
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.069"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            278..786
                     /locus_tag="JX887_001957"
                     /pseudo
     CDS             278..786
                     /locus_tag="JX887_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
     gene            879..2041
                     /locus_tag="JX887_001958"
     CDS             join(879..1155,1155..2041)
                     /locus_tag="JX887_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAX1257935.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2321..3301
                     /locus_tag="JX887_001959"
     CDS             2321..3301
                     /locus_tag="JX887_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1257936.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3423..4841
                     /locus_tag="JX887_001960"
     CDS             3423..4841
                     /locus_tag="JX887_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAX1257937.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4912..6381
                     /locus_tag="JX887_001961"
     CDS             4912..6381
                     /locus_tag="JX887_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1257938.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6391..6858
                     /locus_tag="JX887_001962"
     CDS             6391..6858
                     /locus_tag="JX887_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAX1257939.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6894..7766
                     /locus_tag="JX887_001963"
     CDS             6894..7766
                     /locus_tag="JX887_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1257940.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7847..10381
                     /locus_tag="JX887_001964"
     CDS             7847..10381
                     /locus_tag="JX887_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1257941.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10537..11310
                     /locus_tag="JX887_001965"
     CDS             10537..11310
                     /locus_tag="JX887_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1257942.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11303..12094
                     /locus_tag="JX887_001966"
     CDS             11303..12094
                     /locus_tag="JX887_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAX1257943.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12104..12595
                     /locus_tag="JX887_001967"
     CDS             12104..12595
                     /locus_tag="JX887_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1257944.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12613..13023
                     /locus_tag="JX887_001968"
     CDS             12613..13023
                     /locus_tag="JX887_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1257945.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13027..14427
                     /locus_tag="JX887_001969"
     CDS             13027..14427
                     /locus_tag="JX887_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAX1257946.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14450..14824
                     /locus_tag="JX887_001970"
     CDS             14450..14824
                     /locus_tag="JX887_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAX1257947.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5286 a         2134 c         3045 g         4763 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaggaaata agaaaactaa acttgtatcg
      601 ttaacaaaat atggtcgaaa ggtgtacgaa tcacataatt atttacatga agagctttat
      661 agctcaataa atgaagcgtt agaatcattc tcaccagacc aaatttcaac cattaaacag
      721 attctagaaa aagtatctta tacaatcaat gaatatcaag taagtctgac aagaaaggaa
      781 gattgacatg aaaaaaatga tttttgaatc ggctacacta gactagacag aaaaaataag
      841 gtgtgtaaaa taaatgaaaa cacactggag gaatttttat gtcaagacgt caacgtagaa
      901 cctattcaaa agaattcaaa caacaagtcg tcgatcttta tctcgcagga aagccccgag
      961 ctgaaatcat tcgagattat gagctgacta cctcggcctt tgataagtgg gtcaagcaag
     1021 cgcaaactac tggctcgttt caggaaaaag ataacttgat ccctgaacaa gtagaactaa
     1081 ttgcattacg aaagaaaaat aaacagcttg aaatggagaa tgacatttta aagcaagcgg
     1141 cgctgatatt gggacgaaaa gacaagtaat tgataccaat aagcacaaat actcaatatc
     1201 agcgatgtgt aaagtgttaa acatctcttg ccaaacctat tattatcaag ccaaaccagt
     1261 tgaagatgaa tcagaactgg aagaactcgt tcaagaagaa tttattcgca atcgaaaagc
     1321 ttatggtacc aggaagctga agcagtgctt ggccaatcta ggtcttcaag tgagtcaacg
     1381 cagaatcggc cgtatgatga aacagcgtgg cttgcgttca acatacacat tggctcattt
     1441 caaattccat tcttctactt gtaacgaagc caagaccgcc aatattctag acggaacctt
     1501 cctacaggaa aagtcattag aagcgattgt aaccgacctt acctatgttc gtgttgggaa
     1561 gaaatggcag tatatctgcc tgattcttga tttgtttaat cgagaaatca tcggctattc
     1621 atgcggggag aagaaagatg cgacgttagt caaggaagct tttgcaaaga ttccgtactc
     1681 gttgaataat gtacaacttt ttcacacgga tcgtggaaaa gaattcgata accagacgat
     1741 tgacgaaatt ttatgggcct ttaatatcac gcgttcctta agcaaaaaag gctgccccta
     1801 tgataacgcc gttgcagaat ccacctataa atctgtcaaa gtagaattcg ttcatcaata
     1861 ccgctttgag acattggcta atttgcgatt agagctattt gattacgtcc attggtggaa
     1921 taccatccgg ctgcacggca cgttaggcta tgagacaccg atcagttttc gacagcagag
     1981 attggcgcag cgaatccttg ataatgagct cggatgtgat accggtggcg aggcacctta
     2041 attatttgaa tgagcttctg ccttagagaa tcagattcga ggaggctcgt tgtcaagggc
     2101 agtcggaaca ccagcagcaa gcttacgcaa taccttataa tttttgtcaa aaaaagtgtt
     2161 gccattccac atatatcttt aaacagctat tgccagataa aaataaatga tattatatat
     2221 ataaatactt atccgaaaag gggaatgaga gagtcaaggt tcttggaatg tcgaatagtc
     2281 gagtaggtag attttctatc tacaaccttg ttgtttaaaa atgaaaaaaa ttggaattag
     2341 agaagttgcg aaagaggcaa atgtttctcc tacgactgtg tcgagggtat tgaatgatcg
     2401 tggatatttg agtgaggaaa caaaaagaaa agtttttgat gccatgaaaa aattagaata
     2461 ctatcctaat gaactggcga gagcactttt taaaaacgaa acatataccg taggtttgat
     2521 ttttcctaca attactaatc catttcacgc tgagttaatt caagatatcg agttcgagct
     2581 ttccagcagg ggatataaag tgttgctgtg caatagctta aacaatccaa caaaagaaaa
     2641 agagtacttg acgatgttga gaaagaatca ggttgatgga attatagtag gaacgcacaa
     2701 taaagatatt gcggattatg atattccagg gctacctatt gtagcgattg atagaagtct
     2761 tggtgaaaat acagttacag tatcttgtga taattacagg ggtggggaat tagctactca
     2821 actacttgta aatcatggct gtcagaatat actgtgtatt cggggagata gtaagataaa
     2881 gctacccgcg aatagtagga ctttagcata taaagatgtt ttgaataaat tcatgctgga
     2941 accgttagtc ctagaagtac catttgtaaa agaaatcaat gaaaaaaatg aaataattaa
     3001 gacatatctg gaaactcatc caaatattga cggggttttt gcaggagatg atttattggc
     3061 ttctttggcg attaacaact taggaagttc gggcaaaaga gttccaaaag aggttaaagt
     3121 gattggattt gatggagctc aacaaacatt gatttataat ccagaattat caactattca
     3181 acagcctata gatcaaatat ctaaagtagc agtaaaaaaa ttattgaata tgattaaggg
     3241 cgaaaaggag acggatgaac tttcacttcc agtaaagctc ataaaaaaaa atacagcata
     3301 agttaaatcg gcgaaaaatt ccttcgtcga tttaaaaata tttttatgaa acgggttgac
     3361 atatgaaacg ggttgacata tattagttgt gaagataaaa accttttcac tggaggaaga
     3421 aaatggagaa attattaatt aaaagcaata atcatcaact ttactaccaa cctaaggatg
     3481 tttgggtcgg agatgttatg ccttacggga aagaaggaaa attctttatt tatcatcaac
     3541 gtgatactag aaatccagtt ccttttggag aaccgtttgg ctgggcttta gcaactacga
     3601 aagattttgt tcattttgaa gactttgggg aatctctttt aagaggggat gacaatgaga
     3661 gagaccagtt tatctacgct ggttctgtat ttgaggcaaa tggaaaggtt cacgcatttt
     3721 atacagggta taatcgtgaa ttcttagcgc agggaaagac atctcaagtg ttgcttcatg
     3781 ctgagagtga tgattttgtt cattgggaaa aatcagaaac agcattggag ttagaaccac
     3841 aagaagggta tgatattcga aactggagag atccatttgt cgtttgggat gatgaaaaag
     3901 aagaatattt gctaatttta ggggcgcgaa agggtcagga taaacatcta caaaccggac
     3961 gtttagtgga atttacatca aaagatttaa ctaattggga attcaaaggt gatttttggg
     4021 ctccgggatt gtataccatg tttgaaatgc cagaactttt caagattggt gactggtggt
     4081 atcttgtcta ttcagaatac tcagatggaa ataaaatact ctatcgaatg agtcaaagtt
     4141 tggaaggtcc ttggattaag cctaaagatg aagcttttga tggacgggct tattatgcag
     4201 gtagaacagc ttatgatgga aaacgtcgag tcctatttgg atgggtacca acaaaagatc
     4261 aagaaaatga taaaaacaat tatttatggg gaggtacttt ggttcctcat gaagtctatc
     4321 aaaaagagga tttttcactt ggggtaaaac ccatagacga agtgtggaat gcattcataa
     4381 atttacatga tattgccgat gtagagatag aaacagcaga cacaagagaa gaagtaacgc
     4441 ttgtcaaaaa tagtggaact ttgtttaatt tagaaacaac aatttcattt gatgagaatc
     4501 ttagtgactt ttcactgaga ttatataaaa accttgagac agatgaatct tacgaatatc
     4561 gcttcaattt agatgagggg cgtcttacat ttgataaaaa cccttgttac ccttggtttc
     4621 aatatatgga taaaggactt attagaccta tatctttaaa gcctaaccaa tcttataaac
     4681 taaaagtgat tgttgatgac aatataatga cactttatat tgatggaatc gctcttaacg
     4741 ctcgtgtaca tggttgtttt ggtcaagcaa ttactattac agcaacaaat ggatcaatga
     4801 ctgcaataaa taccaagttt tcaaatgaaa taaagaaata ataaacgtca atcatgtggc
     4861 aggtctgaaa atcaaacatg acctgtcaca tttaaaaggg aggataaatg aatggactac
     4921 aaaaaaattg ccgaagatgt attggaaaac gttggaggaa aagagaatat ctcaagcgct
     4981 acacactgca ttactcgttt acgtttaatt cttaaagaca aaagcaaagc gaatatggaa
     5041 atgcttgagg aaatagaagg tgcaaaaggt gttcttttca atagtggaca gttacaagta
     5101 attttcggaa caggtataat tgaaaaggtt tacaaagagt tcgttgaatt gacaggagct
     5161 aaggaagtat ccgtttctga aatgaaagac gaaggagtca ataattcagg aaatagactt
     5221 caacgagctt ttaaagtttt ctcggatatc tttattccga tcattccagc ttttattggg
     5281 gcagcaatgg ttttaggaat tcgttcgttg attaccactc ctggaatgtt tggaatggat
     5341 ggctcattcg ctgatcacaa tgtattccta aatgatttat ccaaatttct gggtattatt
     5401 gcaaccacat ttgattattt accagtttta gttatgtatt ctgcaacaaa acgttttggc
     5461 ggaaacccta ttttaggatt acttgtagga tttgttatga ttcatccagg actagccaat
     5521 cggaatgatt tcgtcatggg aactataaag cctgattatt ggcatttatt tggattaagc
     5581 attccagcag ttgcgtttca agggggtgtt tttccagcaa ttttgacttc ttggttttta
     5641 gcaaaagttg agaaaattac aaataaatat tctcctcaag tacttgctta cattttagtc
     5701 ccaactgtga caattgttct tgccaacttt gcactatttt tagtgtttgg tccattgggg
     5761 aattttatcg gtaatgtttt aggtggaatc attgatttcc tatatatgaa gatgggtgcc
     5821 tttggtgctt ttgtttttgc aggcgcgtta caaccattag ttgtaacagg aacacaacat
     5881 gctattcaag gtattgaggc aaacttagtc gcaacaactg gattcaatta tatccaacct
     5941 atttggtcag tttcaattat tgcccaaggt ggcggttgta ttggtatgta tttactcttt
     6001 aagaaaaaat ctaaagatag agatattgcg atttcaagct ttattccaac actggtaggt
     6061 attactgaac cggctatctt tgctgttaat ttgaaatatt caatcgttcc ttttgtttgc
     6121 tcgtttattg gtgctggttt tggtggagca tttatgaaaa tttttgatgt aaaagccatt
     6181 ggacaaggat tgactgtatt gccaggtctg actattgcta atccagttct tccttatata
     6241 tttggtaatc tcatagcatt cattttacca atcattttta ttctcgctta tgataaatat
     6301 aaagtgttta tccctgaagc taaacaccgt aaatttgcag aaaaaactga ctcaaaaaaa
     6361 ttgccagttc aagtaaagtg agatgagagc atgttaaatt tttttagaaa aaatgaaata
     6421 agcgttgtag cacctgcaac cggtgttttt gaaaaactgg agaaattaag tgatccagtc
     6481 ttttcaaaag gaatgatggg acaaggattt gcaattgatg caaaaaacga aacgattgta
     6541 tctccaatcg atggttttgt ttcaagtatt tttcctacaa aacatgcctt aggaataaaa
     6601 acaaaatcag gaattgagat acttgttcat gtaggaatag atacagttga gctaaatggt
     6661 gagggatttg atattaaagt tcaagaagga caaaaagtta aggctgggga tattcttatg
     6721 accattaatt ttgtagtttt tgaaaagaat cacaagacta aagatgtcat tgttgttttt
     6781 ccagactacc aagacgaaat tttcattccg aaacttgaag aagtaaaaca aggacaagaa
     6841 ttgtttgttc ttggctaatg ataagtaatt aataatagaa tcgaggaaaa tgtatggttt
     6901 ttggggctat tgaagctggt ggaacaaaat ttgtttgtgc cattggagat aaagatttga
     6961 acatatttga aaaagtcagc tttcccacga ctacacccaa agaaacaatg aatttagttt
     7021 tagatttttt taatcatcat aaagatgatt tagaaggtat cggagtggga tcgttcggtc
     7081 ctattgatat tcattgtgaa tctaaaacgt atggcttcat taaatcaacg ccaaaacttg
     7141 cttggcagga ttttgatttt attggaagtt taaaaaagca acttaatatt ccaactgctt
     7201 ggacgactga tgtaaatgcc tcttgctatg gtgaatatgt ttctggaaat ggcagaggcc
     7261 tttcaagtgt tgtttactat accgtaggaa cgggcatagg aggtggcgct atccaaaacg
     7321 gaaacttcat tgaaggtttt agtcatccag aaatgggaca tatgcttgta aaacgacaca
     7381 ataaagacaa cttttctggg acatgtccat tccacggaga ctgtttagag ggcttagctg
     7441 ctggtccggc aatcgaaaga agatcaggga aaaagggaca agaagtgact gaaaatgacg
     7501 ttacttggga aatagaagct tattacattg ctcagtgtgc atataataca acattgatgt
     7561 tatcacctga tgtcattata tttggtggcg gagtaatgaa acaaaaacac ttaaaaaaga
     7621 aagtacaaga taagtttatt gagttgatca acggatatgt cgctattccc gatgttgaca
     7681 attatattat gacaccaaaa ttgttagata attctggtat tgtaggttgt ttagctttag
     7741 caagagacgt taaagaaaaa tcttaatttg gaaaaaagat cgtctcgact atttgtttgg
     7801 ttgatgcgat ctttttttca attagtaatt gaagggacgc ctaaaagtga aaaaaaaaat
     7861 gaaagatgaa gtattagagt atatcaaaaa taatttaaag tattacgatt tttctgctca
     7921 agatattgca atgaaatttt gtattaaaag aaatgtcgct tcccactatt tgaatcagtt
     7981 attttcagat ggaaaattac taaagaatga ttctgttaga ccagtaatgt tcaagtataa
     8041 tcaacaaaag ccaaaagact gcttttctaa gtttattgga gcagacatat ctttgaaatc
     8101 cactatagat aaatgcaaag ctactgtaat gtatccccct aatggcctcc cattaataat
     8161 aaaaggaaac agtggcgttg gaaaaagttt tttagcaagt ttgatctatc agtatgctct
     8221 tgatagaaaa gtaattcata atgacgcaaa atttgttgtt gtgaattgtg cagattatgc
     8281 aaataatcca gagctattgt cagcagtttt atttggatat aaaaaaggag cctttactgg
     8341 ggctgaaaaa gatactgcag ggatgctatc ttctgctaat ggaggatacc tttttttaga
     8401 tgaggttcac aatctaagtg cagaaaacca agagaaattg tttcttctta tggattctca
     8461 aaagtatcgt aaacttggtg aaagtgtgca atgggagtat gcaaatgttc gccttatctt
     8521 agccacaaca gaagataaaa atacctcttt gttagcaact tttagaagac gcatcccagc
     8581 tgaaatcact ctgccagatt acaataatag aagtacatct gaaaaaattc aattattatt
     8641 tgaatttctt aaagatgaag caattacgat tgattcaaaa atattttgtt cgattgaact
     8701 ttttactgat cttttatcga aaacatttga aggaaatgtt ggagaattga ggaatgaaat
     8761 caagcttctt tgtgcagaag gttatttagg aaataagaga aagtcttcaa tttatttagg
     8821 ggacaaacta gacagcggtt tttggataga tccagaaatt agtatagatt taaaaaaaat
     8881 gtttcttaaa tcactttctg aaattgattt gattgaactt tttcaaaatc acatttcaat
     8941 tgaagaaagc atgagtcaat taagagatag aatacttaaa gagtgtgcag gttcttctga
     9001 gtataattat ttagaaagtg acgaatttat agcattaaga aactatgttg ttaataaaat
     9061 atcaccaatt attgattcga caggtctatg tttattagat gaattcttgg cggatatcag
     9121 tctatttata atgtttattg atgtaattga agaaacatca agaaattttt tgctgtctaa
     9181 gttcagaaaa tttcgtatga aaaatgataa acaaaaatta ttggcaaatg agatttggag
     9241 tagtttagaa gtcgaagaaa gtaaacaaga acttttgttg aaatggatac tttttcttgt
     9301 aaagaagttc tatgtgaaaa taccagaaac ccattgtctg atagttatgc acggtaaaat
     9361 aacagcttct gcgatcgcaa gggaaacaaa taagttgctg aatacatatg tttatgaggc
     9421 tttcgatatg ccaattgaag gtgagactag tgacttaatt aacctaatca acaatttttg
     9481 taaaagtata gatacgacga atggactcat tctgctagtt gatatgggat cattggaaca
     9541 aatgtatgaa aaaattgaat ccaatgtaat aggtgatttg gtaattttaa acaatgtttc
     9601 tacagcttta gcgattgaat gtgggattca agtttgccaa aaaaagccaa ttagtcattt
     9661 ttaccagatg gattttgatt cgtttcaagt taaagttcag tattataaag gattatcaca
     9721 aaagaaaaat gtaatagtat cttgtctctc tggtgagggg atttctgaaa aagttaagga
     9781 tattttaaaa cggtatctcg ataatcaagt ggagattttg atttttgatt ttaacgcatt
     9841 aaagaaaata gcaaaggaaa aagatactat gatttttaag aatacaattt gtgttctttc
     9901 aaccactgaa ttttacattc aaggaatcga ttgtttaaat ttagaaaatc taattaatgg
     9961 gaatcaaacc ttagaaaaat taaataagta tatggactcg gatagctgtg agttctgctt
    10021 aaatgaatta gttaaactct ttactattga aggcgctagt actaagcttc gctttttaga
    10081 ttccaaaaaa gtattcaatg agatagaaaa agtactatat ttgtatgaaa aatattacga
    10141 tgtcaaaatc ccaagttttc tgagaattaa tctatttcta catctttctg gaatgattga
    10201 acgaattatg attggtgatg gaataacaaa tgaacatttg aaagagggag cgcaactatt
    10261 tgatactttt ttaaatgtat caaaagattt tttttcagaa atcaaagata tttactgtat
    10321 tgaaataccc aaaggagagt atgagttaat ctatacaatt tttgagcaga ctattttcta
    10381 aatagcatac tagcgtctaa aaaaatgaaa gggtgtccaa agtatattta gacgctcatt
    10441 taattaatat ttactgtatt ttcccgcttt attggataat gttagttggc acagtaattg
    10501 cttatataaa agtataagaa gaaaggagag aacaaaatgg cgttttggca aacattttta
    10561 gttgtgttgt atggattttt cattaactgg gataaggaag ggcccaaaat cggaacctcc
    10621 caacctgtcg ttgcaggttt cttgaccgga cttattatgg gagatattca aactggactt
    10681 tatatcggtg ggactttgca attaatgaca ctaggtatta ctagttttgg tggtgcatca
    10741 gtaccggatt atcaaacagc agcattgatc ggtacttatt tagcaatctc aactaaccag
    10801 gatgcttcta taggaataac tttagcaata ccggtagcaa tgttaattgt acaactagat
    10861 gttctaaagt ggtcaacaaa catttttttt caacaaaagg cagaaaaatt cgcacaaaaa
    10921 gaagattatc aaaaattaga gtggatgcaa tatttggcat caattaatac aagctttgta
    10981 tctggaattc ctgttttgtt aactgtgata ttaggcccaa cgttagtggg aagtgcaatc
    11041 aattatattc ctgaatgggt taccggtggt ttaaaggtag cagggggact attacctgct
    11101 gttgggatag gaatgctact taaatattta cctacaaaag attactttgc ctatttgtta
    11161 gttggtttcg ttttggcagt ttatttccaa ataccaattt tagggatttc gttacttggc
    11221 gctgcaatcg cactaatcgt atataaaaat agatcaaata atactcaagt agcaccagct
    11281 gcaacaggag gttttgacga agatgaataa gaaactgaca aaaatcgaca aacaagtaat
    11341 tttccggtgg attctcaatg gtgcaacttc attaaattat gaaaaaatgg aagggttggg
    11401 ttatgcgtat tctatgcttc cttttatcaa ggacacatat aaagatgatc ctgaaggaat
    11461 gaaacaatcc gttttagctc acttacaatt ttttaacact acgccgtata cagcgcctta
    11521 cattattggt atgaatgttg gaattgaaaa agaagaaaaa aataagtctt tggaagcagt
    11581 aagtgctctg aaaacaggtc taatgggtcc tttagcggga attggagata gtgtatttgt
    11641 agttattcca tggactattt ttggagcaat tgcagctaat atggcattgg aaggtagttt
    11701 tgttggaatt attttgtgga tactggcatc aattttatta aggattactg cttatccttt
    11761 ataccttgct gggaaagaat cgggtgcgag cctactaact caaattgaaa caaaattaaa
    11821 gtctattact gatgcagtat caattttagg gttaatggtg gtcggtgcac tcattgccac
    11881 agttgtaaaa gtgaatgttg gctttgaatt taaacaaggc gacttaacaa tgaccggaaa
    11941 tgaaatcttt gatcaagtta tgcctggttt attacctgca tgtgtagtag caattgtgta
    12001 ttatttgtta ggacgaaagg ttaaaccagt ttatgtaatt ctattaatct tagtagtttc
    12061 tattgcgtta agagcgttaa atattttgaa gtaggtgttg aatatggatg aaaaaatgaa
    12121 aggtattata catgttcgta ttgatgatcg aatgattcat ggacaagtag caacacaatg
    12181 gacaaatcaa ttgagtgcta acagaattat ggttattaat aatgaagtag ccaatgatga
    12241 cgtaaaaaaa gctgtagttc gcctcgctgc accacctaat gttagaactt caataattac
    12301 aagggaagta gcagttaaaa atattctttc tggtaaatat gaaggacaaa aagttcttat
    12361 tgttgcagtt tctccaatcg atgttaaatt tttgattgat aacggtttac caataacaag
    12421 tgtaaacgta ggaaatttat caagaaggaa tggaacagaa cgcatccgtc cgacgataaa
    12481 tattactgaa gaagagagag aggcttttaa agaactaatt agtgatggag ttgaagtgac
    12541 agtgatacaa actcctagag attcaaaaga atttttaaag gattttattt attaagaaca
    12601 gaggatgagt ggatggagtt tataattaca tctcatggaa atattgccat tggatttgta
    12661 gatacattaa aaatgttttt tggcgataat ttaaattgtc atgtggtaac acttggagat
    12721 gcaggcattg aagaattccg tgaaaacatt gaaaaaatag tttctcaagt aaaaaatcaa
    12781 gaagttatgg tatttgctga cttgattggt ggaacacctt tcaacgaatt tgctaaaaga
    12841 agtgaagtat ttcaaaatgg gtttcaactt cttggtggca tgaatttagg aattttgatt
    12901 gaggctgtca atttgagatt acaaggaaaa aaaagcgatg atatcatcga aaatctaaga
    12961 aatatgaata caattgcgtg tcttgcagat atgcaaagac atactaacga agaggatgag
    13021 tgataaatgc aaaaaatttt ttacaagcct aaagattttt ggtttgggga ttgcatgcct
    13081 ttttataaag atggaacttt ttatctattt catcaacgag atacgagaaa tcctaaacct
    13141 ttaactgatc cttttgggtg gtcactagtt acaaccactg attttgtgaa atttgaagaa
    13201 tacggggaag taattcatcg tggtggcaac gatgacattg atcaatacat ttacgctgga
    13261 agtattgtcc aaggaatcaa tgagtattta gctttgtata ctggacataa tcgcaaagct
    13321 aagttggatg gaaaaacttc agaagtgtta atgattgcaa gttctaaaga tttaattcat
    13381 tggaaaaagg atggcgaagc agcaaaactt gttcctcaag aaggatatga taagaatgat
    13441 tggcgcgatc cttttgcaat ttttgatcaa gatcatggaa aatacgtttt gatactagga
    13501 gctagaaaac cagcaagtaa gaaaaagccg acggggagat tggtctattt tgaatccgaa
    13561 gatttaaaag attggaattt caaaggagac tactgggcta ataatgaatt taacatgatt
    13621 gaaatgcctg atatatttga aattgatgga acgtggtatt tacttttttc agagtattgt
    13681 gaagataaaa agactaaata tcgagtcgga gcaggattat tttcagattg gaaatcacca
    13741 gtagacgaag ctttcgacgg aaaagcctat tatgcagcaa gaacagtcgg aactaatgaa
    13801 actggccgtt ttctaactgg ctgggtggca acaaaagaag gggagaacga tcaaaataac
    13861 tgggattggg gcggtgcact tgttccacat caaattattc aaaagacaga caaaactctt
    13921 ggtgttaaac tgcctgaaaa aataattgag aattttaaag aaatcactcc attttcaagt
    13981 tttaagttag agaaagaatt tggaaaaaaa gaaagagtaa ttgttcctaa aatcgaagat
    14041 tattttctat ttgaaacaac tttgactatt acatcgttaa caaaggagtt tgctttaaaa
    14101 ttatttgtag atagtgatac tcaagaagga tacgaatttc gtatttcatt gattaataat
    14161 cagcttactt tcggaaaaac tccgaactat ccttggcctc aaatgtttga taaggggctg
    14221 caacgaccac tatttttgga aataggcaaa gaatatgaac taaagttaat tgttgatgat
    14281 acgatagctg ttttatatat tgataatgtt gctttaagta ctagaatgta tgataaagtc
    14341 ggaacagcat taagtatgac tgttacggag ggagcaatca aggtagataa actagactat
    14401 tcaataaatt atgaatgtgg attttaaaac aattgaaggg atgatgtaag tgaaattaaa
    14461 tggtttacaa catattggaa ttccaacaaa agattttgga gcttcaaaaa tcttttatga
    14521 atccttaggg tttagtctga ttaatgaaga aatgaatgtg ggaagtaaag tcggcttttt
    14581 cgagttgaat ggaacgataa tagaaatatg ggaagataaa actactgagt gtagaggagc
    14641 cattgatcat ctagcattag atacggatga catagatgag gtattcaatt caattcaaga
    14701 tttaggatat gaattattag ataaaaatat tatggaatta ccgttctggg aaaatggaat
    14761 ccgttacttt aatttctacg gaccaaatca tgagattata gagataagcc aaatgaagaa
    14821 ataaatagat aacgaagtgc tctaagttgg tatgaacgaa aagtacttca ttttttggta
    14881 tcagcatttc aatagtttaa tgagaattta ctatttcaaa ttaattcaaa gtgacagtat
    14941 tttttactta tttggtttca aattttgtaa tccttcctat ttattggaat acactccaca
    15001 ttttgtatac aagtcatatc atgttttagc aaagctctta ccaagcaaag ttataatgat
    15061 gttttccaaa gtttgatctt tcgatggagg ctaacacata ttttttgcag gacagccaaa
    15121 attagatgta tagaatagag tctgtgaggc gtatagacag tttattgtct gtatgccttt
    15181 ttttattttg aaaaattttt agtatttttc gaaaaatgct cactccta
//
LOCUS       DADGHT010000070        15137 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.070, whole genome shotgun sequence.
ACCESSION   DADGHT010000070 DADGHT010000000
VERSION     DADGHT010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.070"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            4..2376
                     /locus_tag="JX887_001971"
     CDS             4..2376
                     /locus_tag="JX887_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257948.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="JX887_001972"
     CDS             2437..3897
                     /locus_tag="JX887_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAX1257949.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /gene="topB"
                     /locus_tag="JX887_001973"
     CDS             3908..6112
                     /gene="topB"
                     /locus_tag="JX887_001973"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAX1257950.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6352..6945
                     /locus_tag="JX887_001974"
     CDS             6352..6945
                     /locus_tag="JX887_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HAX1257951.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6958..7857
                     /locus_tag="JX887_001975"
     CDS             6958..7857
                     /locus_tag="JX887_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAX1257952.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7860..8357
                     /gene="ssb"
                     /locus_tag="JX887_001976"
     CDS             7860..8357
                     /gene="ssb"
                     /locus_tag="JX887_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAX1257953.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8723..8983
                     /locus_tag="JX887_001977"
     CDS             8723..8983
                     /locus_tag="JX887_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257954.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9428..9634
                     /locus_tag="JX887_001978"
     CDS             9428..9634
                     /locus_tag="JX887_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAX1257955.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9682..9885
                     /locus_tag="JX887_001979"
     CDS             9682..9885
                     /locus_tag="JX887_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257956.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            9901..10338
                     /locus_tag="JX887_001980"
     CDS             9901..10338
                     /locus_tag="JX887_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257957.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10331..11038
                     /locus_tag="JX887_001981"
     CDS             10331..11038
                     /locus_tag="JX887_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257958.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11418..11597
                     /locus_tag="JX887_001982"
     CDS             11418..11597
                     /locus_tag="JX887_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257959.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11922..12185
                     /locus_tag="JX887_001983"
     CDS             11922..12185
                     /locus_tag="JX887_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HAX1257960.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12179..12529
                     /locus_tag="JX887_001984"
     CDS             12179..12529
                     /locus_tag="JX887_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAX1257961.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12553..13167)
                     /locus_tag="JX887_001985"
     CDS             complement(12553..13167)
                     /locus_tag="JX887_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1257962.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13481..13903
                     /locus_tag="JX887_001986"
     CDS             13481..13903
                     /locus_tag="JX887_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257963.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13913..14116
                     /locus_tag="JX887_001987"
     CDS             13913..14116
                     /locus_tag="JX887_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257964.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14327..14911
                     /locus_tag="JX887_001988"
     CDS             14327..14911
                     /locus_tag="JX887_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1257965.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5570 a         2451 c         3060 g         4056 t
ORIGIN      
        1 aacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ctagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccaaaaa
      121 atgacgaacg gtcaaccaat gaacgacaag aggaatggcc gttcatggtt taaccagcaa
      181 gaacgaatcg aaaataaagt ccaaagtctg agagaagaga tcaagcaaca agaagaatac
      241 gtggaaaagc ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcgg ctttttcagc cgccacgatc cgaaaatacc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctaga
      661 ccaactgatt ctatgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt cgaattgatc
      781 gatcaactca aaacattgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaggaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaaccaat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaagggt tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctatacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tttagaaacg ccagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagatta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaata tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagataaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagtcgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aaatcattta tgaagaagtc gcaaaagaag aaaaggtcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     3541 cacaaagtaa atgcgttttt tggccagcag ctttctgtta acgattcaat agaagccatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagtttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc gcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggactg gaacgatcaa ttgaagcatg agatccagca acaagaaatc
     3841 agaaagcaaa aacgtgccat gttgtttcaa caaggcagac aacaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     3961 tagcttctct aaagccactc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     4021 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gaattagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agaacatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagtag gcgccgatca aggaaaaacc tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagacg caaaagagac
     4381 ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     4441 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gcttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttgcaggaaa agattagaaa
     4561 tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg attcgccaag ttgaaaccga
     4741 gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagacac tttggaagcc atgcaaggct tgtatgaagg
     4861 gaaatatcta agctatccgc gaacggatac cccttacatt acggaagggg aatatgcgta
     4921 tctgttggat cacttagacg aatacaagca ttttttgagg gctgaagaaa tttcgactcc
     4981 tattcataca ccgaatagta ggtacgtgaa caacaagaaa gtccaggaac attacgcaat
     5041 cattcctaca aaaacagtta tgacagaagc gacgtatgaa agtctgacac ctttacaaca
     5101 agcgatttac gagcaagttt taaaaacgac agtggcgatg tttgcggaaa aatataccta
     5161 tgaagaaaca acgatcttga cgcaagtcca gcagcttcag ttaaaggcaa tcggaaaagt
     5221 accgatagat ctaggttgga agaagttatt tggcaaagag agcgacggaa aagagaagga
     5281 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtag atctacaagt
     5341 ccttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcgat
     5401 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     5461 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     5521 tatcaaggta gagaaaaata agcttgtggt gacgaataaa ggggttttgc tttgccaagc
     5581 tgtggaaaaa gagccgctgc ttacgagtgc cgaaatgacc gccaaatggg aaagctactt
     5641 gttaaagatt ggagaacgaa aaggaacaca aaccactttt ctagccaata tccaaaagtt
     5701 tgtctctcac ttattggaag tcgtcccagg acaaatccaa tccattgatt ttggatcgac
     5761 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     5821 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     5881 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggagatt attcaaaata gccgaacaag ccaaccagtg aaagggttaa aaggtcagaa
     6001 gggttcgttt gaagcaacga ttgttttaaa agaagacttc actacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact tcaagaaaag aacacgacgc acgacaaaat aatggagggt
     6121 taatcttatg cgtaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagccaaaat
     6181 tcgttcagaa caagagaaat tacgtgccag taaaagaaga cttcagcaat taaagaacca
     6241 gcaacggatt caaaaagaaa tcgaattaga tcgatagaca ttaaccttgt tacaaataca
     6301 ctatcatgat atatttaatg tagtgtattt gtaacaaaag gggggaagta aatgcaagag
     6361 aaactgaaag aattgttggc tattcgcgat ggaaatttat ctatgaagga agccagaaaa
     6421 ttaggaatcg cagcaaccac tgtacaaaga ttggtgaatc aaggaaaatt gatcaaagtt
     6481 gatcgtggtt attatgtaga ggatggtcat ggaatagatg atttattttg gcttcagcaa
     6541 cgtttttcca ggggaatctt ctctcatgaa acgactttag atatttacca gctttctacg
     6601 aatatgccga aattcattca cttaactttt ccccatggat ataacgttga tcgttcaatt
     6661 acaaaagagc agcagttaca atttcatttc gtgaagaaag aagtttatga actaggaaaa
     6721 gtagagggaa cttcctttca aggaaatcct attactatgt atgataaaga gcgtacactt
     6781 tgtgatattt ggaatccgag atatgaaatt gaatatgaaa tgaaattaga agcattaaaa
     6841 gagtacatgg aagacccatt gagagatcca agtaaattaa gagattacat gacaaaacta
     6901 catgtagaaa aagaaatgaa ataccacatg caaagcttat attgatggag gaaaaagatg
     6961 acaccgacac aatttgcagc aaaaacaaga aatttagcaa agaggacagg attaaatgca
     7021 cagttagtac aacggcattt tatgatggat cgtttaattg aacaaatttc tgaatctaag
     7081 tataaaaatg atttcatttt gaaaggtggc tttttattag gatcaaaata tggaatcgat
     7141 agaaggacga caattgatat cgacacgaca tttagaaata gcaaattaac tgaagaaaaa
     7201 ttgaagagta tttttaatga tttaactagg aaacccacga aagaaggtat tgttttctct
     7261 attcaaggaa tgaaggaaac aagagaagcc gatttttatc ctggatttca aattaaattg
     7321 gtggctaatt tagagaaagt acgtgtgcca tttaaaatgg acgtgacaac aggagattct
     7381 atttatcctg aagtagatac acactatcac caattaatgt ttgaagataa aaaggtggag
     7441 attccagctt atccaacagc acaaattatt gcagaaaagc taagtgctac gttcagcttt
     7501 ggcacagata attcgagagc aaaagattac tacgacttat ttaccattcc gaaactagaa
     7561 aatatcgata cgaaagagtt atacaaaagt gttcgaaata catttacaaa acgtggggat
     7621 acaaaaccgt tgtcctttta ttatgaaaga gaaatggata agatcatagg aaatgactat
     7681 ttggaaaagc agtgggaaaa atatcgctca gttaacacgt ttgcgaattc catttcattt
     7741 acagatacag tcaacgaaat tgatcaccta atgaaaagtg tgatcaaaat tgaaaatcaa
     7801 gaaagaaaac ggcagtttaa aagatcacaa caaatgaatc aagaaatgga gagataaaga
     7861 tgatcaataa tgtaacttta gtaggacgct taaccaaaga tccagattta cgttataccg
     7921 cgagtggtac tgcagtagcg acttttaccc tagctgtcaa ccgaaatttc acgaatcaaa
     7981 acggcaatcg agaagctgat tttattaact gtgtgatttg gcgcaaacca gcagaaacaa
     8041 tggtgacatt agctaaaaaa ggtagcttga ttggtgtagt tgggcggatt caaacgcgga
     8101 cttatgacaa ccagcaagga caacgtgtgt atgtgacaga agttgtggcc gataatttcc
     8161 aactattaga aagcaaagca gcgacagaaa gccgtgcgca cgctgatcaa tcgtccacca
     8221 gtccaagcac caccactttt gaacaacggg atacagcgac gcctaataac aatggattga
     8281 acgctttaca gaatccattt gggaatccat ttggtggaca atcaatcgat attagcgatg
     8341 atgatctacc gttctaagta gcattttcta ttggttgcat ttgctacggt ttatgttata
     8401 atttagtcaa caaaaagaat tttcaatcta taaccaaaaa ccactagctg gcgggctagt
     8461 ggttttcttt tacgtttcta ttataagaat taacgggtag gcttactgtc tttcttggca
     8521 aatttacaat caagccattt gcagatatag tgcgcggcta cttctgccat gattgcaaaa
     8581 acaaaatcaa aaagaatttt caaacctata acctcctccc cttgccagat taggccgggg
     8641 tagcagacag caagactatt atagcataat tgaaatatcc aaatgattgg atttttgcta
     8701 taattttagc gaggtgattg tgatgaacaa atatgttggt ttgcttgata aaatccgagt
     8761 aataaaaacg caaccgttat tggttcgctt tactttacaa acgattcatg aatcgattaa
     8821 ttgtgtagtt gcagatattg aaattatcga taaattgcta attatggatg atggaaaata
     8881 caatattgcc gtcacaggtc acttcaataa acgaaatcag ctagttattg ctagcatgta
     8941 tgttagaaat cccgatcatt ttacgcgatc gatgggcata taaaaaaaga agagttgcaa
     9001 tcctaatgta ggactgcagc tctttttgtt ttacatagaa acaagaaaaa tgaaaaggcc
     9061 tttttaggaa ggcgcgagcg ccttctcaat tgaaaaacct ctctcactcc aaccgccacc
     9121 gccgttcgag aagaaaggaa gtgaacgttg cacgttcact aagataaagg gtcttgcaaa
     9181 gcaagacaaa atagaaaaaa cttcctctca ccaaaaggtt cgttcctgtt cgttatctct
     9241 ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     9301 gggtaaatgg cacgctgcgc gcccttgtcc ttgtcgcttt tcgttgattc attctggcca
     9361 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     9421 atcaatcatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     9481 ctatcatgca ccacatactg tcgaatgcga ttgtggacaa agagcgaaat gtatcaaaag
     9541 ctatcgtttg tatcaatgtc caacatgcgg aaaaaaatac accttgtctt atggcgatta
     9601 tattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cataacataa attattgact
     9661 gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa agtagcagaa
     9721 gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga tgcaccgact
     9781 atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca agaaaacatg
     9841 gaaacttatg aaaacgaata ttggttaacc aaattagaga actaaaaagg agaaaaaaat
     9901 atggctcaaa attactatga cgaatttgtc aaattacctt tggataaaat ggcacaaaaa
     9961 atggaggata tgacattcct ataccatgag acacgtgttc caaaaaaaca ttataaggaa
    10021 agattgtcgg tagctgtgga agaaatgatt gaatcaggtg tcgaaatgaa tctcattgcg
    10081 acgtactatc gaacactgga agaactgaaa aaacaaaatg caaaatggtt tttccaagcc
    10141 ttactatgct tggaagtagg tgtcaaacca agcactatta aaccttctga atatcaagct
    10201 ttagaactaa cgtatgggaa atttgtcgaa acgaaaaaag ccaagactgt ttcaagtgaa
    10261 tggttagatt attttgaaaa tatcaataag tatggcgcct attacaccat gaaaaaggag
    10321 gacaacgaaa atgaataagg tgatttatca actaacaacg gaagatgtgt cacacttttt
    10381 aacaaacaaa gaacatttga atgaagtaat cagacggatt caaaaagact ttagttgtat
    10441 ggaagaaatg aagtacttta ttcaaagagt cgaagaacaa ttgtatttgg aaagtgaaac
    10501 gagtcaaacg aaggtcacag tcagcaataa ttatttagac gtgtataaac atcgtcctga
    10561 aacggtaaaa aaaggaacgg agcttctacg actagaaaca gaaaaataca tcatgaatgt
    10621 ttacctagaa aggagtgaac tggtcgaaaa ctttgtcagc tgcacgattt gcaggaaaca
    10681 ctattactca gaatcagaat attattcaat ttttgagagc atggaattaa tggaagaaga
    10741 aatggaagag ctaaacagca aaaatgcgac gatagacgat tattatcttg tatttactag
    10801 atttttgacg tgtggaacgg aatctatcgt gttaatggga atggattatg aactcgctgt
    10861 acccgaagca tttttgaggg aatatgtaga agaagtagat aacccaggcg acgactggta
    10921 cacgacttta actgattttt tagataccta cacttacgac gatacagaag aaatccaaaa
    10981 tgaacttgac cgtaaacgaa tgccatatca acgatttgaa aggaaaaaaa ggcaataatc
    11041 atttataccg aaaagtgaga atgtgtgaaa taagaacaaa aaccttgaaa ttaagggaat
    11101 ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataag
    11161 cgggcaaagc ccgataacct aagagaaaga aggagatcca tatgaataaa atcattcctc
    11221 tgttgttcgt actgtgtatt ggcgagatac ttatgcgtca tggtgcagct gtacatttaa
    11281 acttcgtagt attcttagga atactagtat tttgtttgat tttttggcgc tttgtgttag
    11341 cccttgtgag tctactattc aagttgattg cagccatatt tttcataggg ttatttcgat
    11401 gaaaggagag agtactaatg ccaattgcaa taggaaataa acggttaccc gtgacattag
    11461 atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtacggaaaa agtgaatcta
    11521 agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga tttgatatac
    11581 cagcactaaa aaagtgacgt cacttttcat ttgaagaaac aaaagtgata gcacttaatt
    11641 gttcctacta tttagaatat tttctatgtc ctttttattc cattttgtat caataactat
    11701 gaaatcttta aagtatccag atcaattttt ttcttacctg attctaaaga ttttgttttc
    11761 ttaaacatat tatgatttcc tttcgactat tttcatataa atgttaacat agtttatgga
    11821 ttcatggaat gttaatctaa tttaatagaa aaggataatt aagtatatac gttttttctt
    11881 atgtatgtta tactatgtat atacagaaag aggtgtctac tatggaaatg ttacctataa
    11941 aaaaatgggg aaatagtaat ggccttagat tgccaaagta tattatggaa tatcttggaa
    12001 ttcatacaga agacaaagtg aagataatac aagaagaagt aaacggtcag aagcggctaa
    12061 ttatcgaagc ggctaatata gaaaatgaat taacaattga acagttattt gaaaattaca
    12121 ctgatgaaag aaatcatgtg acgattcaaa atttaggtga agcagtaggt aatgaaaaat
    12181 ggtgagaaaa cctagacaag gcgatattct attattgaat acagcacctc gatctggaca
    12241 cgaacagaca ggtaaaagac cttatattgt tttaagtcat gatattattg cggattatag
    12301 taacgttgtt acagttgctc caatttctag tacaactaga aactatccgc tatatgtaaa
    12361 tataaactca gaatatgaaa tgaagacaac aggaaaagta ttattagatc aactaacgac
    12421 aattgattat gaagccagag agtgtatttt tttggaaaaa gcgcatgata gtttagttga
    12481 ggagttattg atgaaagtta gaacagtttt tcaaaaagta agcaaataaa atagaaacag
    12541 cagcatgatc aactattcgt gattgaccat gctgtctttt tttattctat atacggtttg
    12601 tctcgtaaca ttgtagtctt ttgcaatctt agcgatcgca acaccttttt ttagatcctc
    12661 aacgatgttt ttataaacaa gacgacgttg gggatctttt gcattggcac tgtatagctt
    12721 aggacgtcct ttataaacac cgttcgcttt tgcaatctta atgccttgtg cctgacgtcg
    12781 tttagattcg gtacgttctt gttcagcgat catggccaaa atttgaatga tcaaatcttt
    12841 aatgaattta tccaggagag gattgccaat tgcttcggcc atgatcggta gacttgtgat
    12901 gatcagctgc acatttttct tcttcaagta attgactgaa gcgatgatct cgtcgtaatt
    12961 tcttccaagt cgatcaatag cttccacaat aaaaatatct tgatctcgga cgaaatccag
    13021 tgcttcttga aaaacaggtc gatgagtaat cgttgcgcca gattgtttct caatgaaaat
    13081 tctctctgca ccgaattttt tcatttcttc aatctgccgt tgttcatttt gatcgatgga
    13141 tgagacacgt atgtatgcaa ctctcaaaat ttttacctac tttctgcaac tatttaaaaa
    13201 acaccctaat catacacgag aaaaccagat ttttcaatgt cgcggtcgtg tctagttagg
    13261 gtatacctta tatagacaaa aactaatgat ggaggaaata gtatgtgtca cttttctttt
    13321 taaatggcaa tattttttgt aaataaatgt caatcaagaa aatttaaacg attatgacat
    13381 taaaaatata ttttatgaat tttctagtat ataacttgat ttatctgtta agatttatta
    13441 agaaaacgtt ttcttatttt tgatttcgag gtgatagaca atgaaaaata agtttatttt
    13501 atctttaggt attttaacta ttggaattag tgtaactgga actacaattc ctacatttgc
    13561 tgatagtaca aatgaaccaa ctactgtagt agataataac caagaattaa ctcctttaga
    13621 taggaacgga atagccattg gtaacccaac taacgactta actgttactg aaaattattt
    13681 aatagtttct ccattacttg ctcgagcagc ttctaaaacg atacgagtga caggaacgat
    13741 gatttttgat aaagttggtt ggccttctag acctcctcaa tcacggaatt ggaaagaaaa
    13801 aagaaatggt tattggtact atggaaaatt gtatttacaa agttataaat cagctggaaa
    13861 caattggatt gcgacttatt caggaacctt aactagaaag tagggatttt ttatgccaga
    13921 atttgtgaac acaccaaatt tttatcaaga tagcgatatt ctaagtaaaa ttaatttacc
    13981 gaaagaagaa tcagctttac aagttcagcg aactttacag gagacacaaa aaattcaaaa
    14041 atcaatttct aatctagaag attctgaaga aaaaagaaaa aaaagagacc aaaaaacata
    14101 tcaaaaagaa aaataatgat tttaaaaaaa gagtgtctag tcgacattct ttttttctaa
    14161 ttgaaagtgt tcataaaatc acccatttct ggacactttc tttttttgct ttatttttca
    14221 aaaaaacaat tcatttcatg ttcataaacc cataacaata tctatgttca gttaaactat
    14281 atggataaag ttatgttaca ataaaattaa tgaaggagtg atttttttga aaataggata
    14341 cgcccgggta tctactggtt tacaaaattt ggatttacaa gaagacagcc taaataaatt
    14401 tggttgtgaa aaaattttta ctgatcatat gagtggggca aaaagtaatc gaccaggatt
    14461 agaaatggcc attgattttg ttcgctctgg cgatacactt gtcgtttggc gcttagatcg
    14521 tttaggtaga aatatggaag atttgatttc aatcgtcaat cgactgaatg agcgtggtgt
    14581 gagttttcat agtattcaag aaaatattac gatggacaaa tcaagttcta caggacagct
    14641 catgtttcat ttgtttgcgg catttgcaga atttgagcgt aatttgatcc tggaacgatc
    14701 cgcagcagga cgagcagctg ctcgtgcaag aggacggttt ggtggtcgtc ctgaaaaatt
    14761 gtctgaacaa gatttggaat tactgaagac tttagtggat agcggtacac ctattaagac
    14821 tattgcggaa cggtggaacg tctcaagaac caccatttat cgttatttgg caaaaatgga
    14881 ggagaaaaat ggaaagacaa attctcatta gtttttgtca tttaatgctg aaaatttttg
    14941 ccatttatct agaaaagtga caatagtatg agaatttttt gtaagtgtct actgataact
    15001 tattctcaaa tgttgtaagg attttattca tttgttaata ttaaagaacg gaactccaaa
    15061 aaagtccgta ctctaatttg cagtctctca ctcttttaga gtgagagttt ttattagatt
    15121 ttcaaattaa ttagtaa
//
LOCUS       DADGHT010000071        14815 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.071, whole genome shotgun sequence.
ACCESSION   DADGHT010000071 DADGHT010000000
VERSION     DADGHT010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.071"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(296..1024)
                     /locus_tag="JX887_001989"
     CDS             complement(296..1024)
                     /locus_tag="JX887_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1257966.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="JX887_001990"
     CDS             complement(1002..2576)
                     /locus_tag="JX887_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1257967.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="JX887_001991"
     CDS             2805..3743
                     /locus_tag="JX887_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1257968.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="JX887_001992"
     CDS             3755..4666
                     /locus_tag="JX887_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1257969.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="JX887_001993"
     CDS             4690..6162
                     /locus_tag="JX887_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAX1257970.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="JX887_001994"
     CDS             6213..6824
                     /locus_tag="JX887_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAX1257971.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="JX887_001995"
     CDS             6854..8767
                     /locus_tag="JX887_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HAX1257972.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="JX887_001996"
     CDS             8895..11876
                     /locus_tag="JX887_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HAX1257973.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="JX887_001997"
     CDS             11873..13534
                     /locus_tag="JX887_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HAX1257974.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="JX887_001998"
     CDS             13574..14506
                     /locus_tag="JX887_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAX1257975.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         4815 a         2333 c         2978 g         4689 t
ORIGIN      
        1 atttaaataa ctacatccat ttattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatgctttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agcgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagt
//
LOCUS       DADGHT010000072        14482 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.072, whole genome shotgun sequence.
ACCESSION   DADGHT010000072 DADGHT010000000
VERSION     DADGHT010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.072"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(142..837)
                     /locus_tag="JX887_001999"
     CDS             complement(142..837)
                     /locus_tag="JX887_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAX1257976.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(927..2027)
                     /gene="ychF"
                     /locus_tag="JX887_002000"
     CDS             complement(927..2027)
                     /gene="ychF"
                     /locus_tag="JX887_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAX1257977.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(2036..2227)
                     /locus_tag="JX887_002001"
     CDS             complement(2036..2227)
                     /locus_tag="JX887_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAX1257978.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(2248..3138)
                     /locus_tag="JX887_002002"
     CDS             complement(2248..3138)
                     /locus_tag="JX887_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAX1257979.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(3125..3892)
                     /locus_tag="JX887_002003"
     CDS             complement(3125..3892)
                     /locus_tag="JX887_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAX1257980.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(3904..4617)
                     /gene="rsmG"
                     /locus_tag="JX887_002004"
     CDS             complement(3904..4617)
                     /gene="rsmG"
                     /locus_tag="JX887_002004"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAX1257981.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(4849..6750)
                     /gene="mnmG"
                     /locus_tag="JX887_002005"
     CDS             complement(4849..6750)
                     /gene="mnmG"
                     /locus_tag="JX887_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAX1257982.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(6767..8164)
                     /gene="mnmE"
                     /locus_tag="JX887_002006"
     CDS             complement(6767..8164)
                     /gene="mnmE"
                     /locus_tag="JX887_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAX1257983.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            8508..8846
                     /locus_tag="JX887_002007"
     CDS             8508..8846
                     /locus_tag="JX887_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1257984.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(9014..9772)
                     /locus_tag="JX887_002008"
     CDS             complement(9014..9772)
                     /locus_tag="JX887_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAX1257985.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(9790..10608)
                     /locus_tag="JX887_002009"
     CDS             complement(9790..10608)
                     /locus_tag="JX887_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAX1257986.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(10605..10961)
                     /gene="rnpA"
                     /locus_tag="JX887_002010"
     CDS             complement(10605..10961)
                     /gene="rnpA"
                     /locus_tag="JX887_002010"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAX1257987.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(11079..11213)
                     /gene="rpmH"
                     /locus_tag="JX887_002011"
     CDS             complement(11079..11213)
                     /gene="rpmH"
                     /locus_tag="JX887_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAX1257988.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            11737..13071
                     /gene="dnaA"
                     /locus_tag="JX887_002012"
     CDS             11737..13071
                     /gene="dnaA"
                     /locus_tag="JX887_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAX1257989.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            13269..14399
                     /gene="dnaN"
                     /locus_tag="JX887_002013"
     CDS             13269..14399
                     /gene="dnaN"
                     /locus_tag="JX887_002013"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAX1257990.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
BASE COUNT         4018 a         3051 c         2592 g         4821 t
ORIGIN      
        1 ttttgaacac cgtttatcgt aaaaagggac tgtgacaaga cttttgtcac agtcccttac
       61 tattatttaa ctatggataa acaaaatgag gttctttact acccctagat atctagcaaa
      121 atagctgatc tttttgctag tttatcttct tgggacggat aaacttccaa taatcccgta
      181 ttttttcttc aagtagtaac ggattgctaa agcagttgcc ccgataatga taactactac
      241 tggatctaat actggattga taactggtgg caatagtgtt gtcgcagaaa acagtacgac
      301 ccaaagaagt gtcgttccac ctaggataag caatgtctta cccattcctg gtttcttgct
      361 tcgatctgct ccgggatatt catattgata gatgtatttg tacatcatat aaaagaccca
      421 gccaccgatt gcagaaccta gaacgagtgt agaaaagcca taagctggcg ttgttccacg
      481 tgaaaacaat ccggtaatcg caatcatgat acttaataga ccaagcaaca gcaacgtatt
      541 atctaaccac atcaataaag gggtggatga attttttact tctgctggct tattgatgat
      601 tgcttccgtt ctttcagaga ctgtcccaaa caattgacgg gctgttcttc cgcctttttg
      661 ttctgcaact aaagtaggca gaatgtcatg aagggctttt actttttctt cttcagacaa
      721 attcgctgct tctaaagatt ttttcaaatc aaaaatgtac tgttgatttc ttttggttaa
      781 ttttgtttct aaactattgt tttcttttac gattgctcgt aattgttctg gttccattat
      841 ctaatagtcc tccttagccg ttccttttct caacggtcgt cacaaaagac attctaccat
      901 attctacagc tagtttgata gcccttttac acattaaagc ggaataacat tacgtcgccg
      961 tcttgtacga cataatcttt tccttctaat cgaacacgtc cagcttcttt tgctgcatgc
     1021 atgtttccgt aatgatccaa gtcttcaaaa gagacagttt ctgcacggat aaatccgcgt
     1081 tcgaaatctg aatggatgat tcctgctgct tgtggtgctt tgattccttt tttgaatgtc
     1141 caagcacgta cttcttgttc cccagcagta aagtaagtag ctaagcctaa caaatcataa
     1201 gcagcacgga tcaactgatc caaacctgat tcttcgattc ctaaagcttc taaaaattcc
     1261 gctttgtctt cttcatctaa ttctgcgatt tcttcttctg cacgagcact gaccacgatc
     1321 acttctgcat tttcttctgc agcaaagttg cgcacttctt gtacataatg attcgcgtct
     1381 gcatctgcta cgtcatcttc tgagacattg gctacataaa gaattggttt tgtcgtcaat
     1441 aaaaatagtg atttaacgat tttttgttct tcttcagtaa attcgatcgt tcgggcagat
     1501 tttccttctt ccagtacagg tttgatttta tccagtacag ctagttctgc cactgcatct
     1561 ttatctttgg ttttagcaac ttttgctaca cgagtatagc gtttgttgat agattctaag
     1621 tctgctaaca ctagttccaa gttgatcgta tcaatatctt ctagtggatc aacacgtcct
     1681 tctacgtgag taatattatc atcatcaaaa cagcgaacaa cgtgacaaat agcgtctact
     1741 tggcggatat ggcttaagaa ttgatttccc aaaccttctc ctttacttgc gccttttacg
     1801 attccagcaa tatctgtaaa ttcaaaagtc gtcggaacag tttttttcgg atgtacaagt
     1861 tctgttaagc gttgcaaacg ccagtcaggt acttctacca tccctacgtt ggggtcgatc
     1921 gtcgcaaagg gatagtttgc tgcttctgct cctgcttttg tgatcgcatt aaacaaagtt
     1981 gattttccta cgttgggcaa cccaacaatt ccagcagtca atgccataaa tttattcact
     2041 ctttctctgc atttttttca attacttttt ttaatttctt ttcaaaatct cgacgggtca
     2101 tcatgacgat atgtccgcaa ttcatacatc tgattttgat atctgcgccc attcgaatga
     2161 cttcccagcg attcgtctgg caagcgtgag gttttttcat ttcaacgata tcgtgcaagt
     2221 cgtacataaa aatagcctcc tttttgttta ttcttcatca aattgaatat tcaagatatc
     2281 aagaattcga gtcaaatctt tttgagaaag atattcaatc tcgatcttac ctttcccatt
     2341 tttttcttgg atagctacac ttgtaccaaa tttatccatc aaacgatctt cgctttctcg
     2401 gatataatat ggtttttcct ttgctagcct tgggattttt ttcttttctt ttccatcatt
     2461 ttgatttaac tcagaaacaa gctgttccag ttggcggaca gttaaatttt cagttactgc
     2521 acgattggct aatttcaaga tcaatgtttt attttttaaa cctaacagcg tacgggcttg
     2581 tcccatagat aaacgctgat cttgtaccat ttccttgaca agatccggta aagaaagcaa
     2641 gcgcaaataa ttggcgatat aaggtctgct ctttcctaaa cgactagcta cttctgcttg
     2701 tgttagtttc aggtttttca tcagcatctc atatgcttct gcttcttcta acggattcag
     2761 atcttctcgc tgcaagtttt ccagcactgc tacttgcatc atcgcttctt cgtcaaagtc
     2821 tctaacgata gcagggatcg tttctttttc agctagtttg gacgctcgaa aacgtcgctc
     2881 ccctgcaata atctcatatc cttttactgc ggaacggcgt acgatgatgg gttgaaagac
     2941 acctgattgt tcaatagaat tagctagttc ctgcaaagat acttcttcaa atgttttacg
     3001 gggctgatac ggatttggtc gcagctcatt caatggtagc tggacaacgg tatcatcttt
     3061 tacatccacc gtctctaagt tttctaaatc ttgaaacagt gcatcgattc ctcggcctaa
     3121 tcctttactt ttcttcacga cttaccactt cctttgccaa tgcttggtag acttcagctc
     3181 ctcgagaacg tggatcgtag tcgatgatcg gttttccatg actaggtgct tctgataaac
     3241 gaatatttct tggaatgatc gtttcgtaaa ctttttcgcg gaagtattta cgtacttctt
     3301 ctacgacttc atttcccaga tttgttcgtg catcatacat tgtcagtaag actccctcga
     3361 tctctaattc tggattaaag tgtttttgga ctaaacgaac cgtattcagt aattggctta
     3421 atccttccaa tgcgtaatac tcacactgaa caggtatcaa aatcgaatca cttgctgtaa
     3481 atgaattgat tgtcagatgg ccaagagaag gcgggcaatc gatcaaaata taatcatact
     3541 gactgcttac ttctgctaaa gatcctttta atcttgattc tcttgccatc attgacgtca
     3601 attcgatctc tgctcctgct aattggagag tcgcaggcac aatactcaaa ttttcgtgtt
     3661 cagtgatcaa agttgcctca tcaattggca attcattgac tagaacatca tagatgtctc
     3721 ttgtcacatc aggttttctg atcccgacac cactggtagc atttccttgt gcatccatat
     3781 ccactagcaa tacttttttg ccaaggctag caagacaagc acctagattc accgtcgtcg
     3841 ttgttttgcc gacgccacct ttttggttcg caacagatat tatttgtgcc atctcttctc
     3901 ctcctatttg attggctgct tattaggcag tccgggcttt cttgggtatt tctttggggt
     3961 tggtttcttt ttttgaataa cgatgatatg ccgttgatca gagacattcg gcaaggtaac
     4021 cgcctcttct ttgaggaatt taccacctaa taaagcaatc gcttgttttg cttctgtcaa
     4081 ttcctcttca ctttttgctg ctttcaatgc ataaaaatag ccttcttgtt tagccaaggg
     4141 caaacacaat tccgctaaca cattcaaacg agcaaccgca cgagcagtga caaggtcaaa
     4201 tgatgcacga aagtgaggat tttgcccaaa tgtttctgcc cggtcatgat ataaggaagc
     4261 atcgattcct aataatcggg ttaactcaga taagaaggtt attcgtttat tcagagaatc
     4321 aacgatcgtt atctgcagtt ctggaaaggc aatttttaaa ggtatgctag gaaaccctgc
     4381 ccccgaacca acatcgcata aagataaagg ttgcgtaaag tctacttcaa atgctaatgt
     4441 aagtgaatcg taaaaatgct tcagatatac gtctttttca tccgtaatag ctgtaaggtt
     4501 catcttttcg ttccattcga ctaatgtccg ataataaata gcgaattgat tcatttgatg
     4561 atcggtaagc tctatccctt tttctgccaa ggattggcga aattcttctg gtatcataaa
     4621 tattcctttc attgtgaaac agcaattgtt tcacagattc tctccctact ttaacgcaaa
     4681 atctctagac atgcaatcct tccatatgga ttcttaaaaa tttgaaaagt aagaaaagcc
     4741 gatagacttt ttctttctag tatgactcat aaaatataca cagaagagag aactagcttt
     4801 gagcaatttc tgcaaaaact agttctctct tctatttatt attacgtatt acgctggttc
     4861 actgactttc gcaatcttcc cttgttcgat atagaccatt aggatactta ggtctgcagg
     4921 gtttacgcca ctgattcggc tagcttgggc aattgtttct ggttggattt tctgcaattt
     4981 ttgttttgct tctgttgcta atccgttgat tgctgcgtag tcgatgtttt ctggaatctt
     5041 tttcgcttcc atgcgtttta atttttctac tttttccatg gcttttttga tgtagccttc
     5101 atatttgatt tggatttcta cttgttcgat ttcttttcgt gtcaattctt cattttctgg
     5161 aataaaccgt agaagttctg cataagtaat ctcaggacgt cttaaaaagt cgcttgctag
     5221 tacaccatct tttaatggtg ccgcattaat cgttgctaaa aagtcttgga cttcttctgt
     5281 tggtttgatt cgtacattca tcaaacgttt gatttcttgt tcaactgctt cttttttctt
     5341 caaataattc ttgtattgat cttcttttac taagcctaca cggtgaccca tttctgttaa
     5401 tcgcaaatct gcattatcat gacgtaaaag cagacggtat tcagcacgtg aagtcagcaa
     5461 acgataaggt tcgttcgttc cttttgttac caaatcatcg atcatgacac cgatgtaacc
     5521 gtcacttcgt ttgatcacta aaggttcttt tccctgaact ttcaaagctg cattgatacc
     5581 ggcaatcagc ccttgtccag ccgcttcttc ataaccgctt gtaccatttg tttgtccagc
     5641 tgtataaaga ttttcaacga ctttagtttc taatgtcgga cggagctggt gtggctctac
     5701 tacgtcatat tcgatagcat atcctgtacg catcatttct actttttcta atccagcaat
     5761 agaatgaagc atgttgactt gaacatcctc tggtaaagaa gtagataaac cttgaacata
     5821 gacttcttcc gtatttaagc cttctggttc caaaaataat tgatgacgtg gtttgtctgc
     5881 aaaacgcacg atcttatctt cgatggatgg acaatagcga gcgcctaccc cttcaacgat
     5941 ccctgtaaac attggggcac gatgtaagtt gtctcgaata atttggtgag tcgtctcacc
     6001 tgtataggtc agccagcaag attcctgatc tagtttatag gcactatctg gtgtgctgaa
     6061 gctaaaatga ttcggctctt tgtcaccagg ctgctcttct gtaacagaat agtcgatcgt
     6121 acttgatttt actcgaggcg gtgttcctgt tttgaaccgt tcgatagcaa agccaagttc
     6181 ttttagatga ttcgctagtc caatagaagg ttgagagtta ttcggacctg atgaatattt
     6241 caattcaccg ataatgattt ctccgcgaag tgctgttccg gctgtaataa caactgcttt
     6301 ggcccggtag ctcgctcctg tggacgtcac tactccatga caaacaccat cttcgacgat
     6361 cagttcttcg acgattcctt gtcttagcgt caaatttggt tctttttcga tcgtatgttt
     6421 catttctgtt gaataagcat gtttgtctgc ttgtgctcgc aatgctcgga cagctgggcc
     6481 ttttcctgtg ttcaacatac gcatttggat ataggtttta tcgatattct tacccatttc
     6541 tccgcctaac gcatcgattt ctcgaacgac aacgccttta gctggtccgc ctacagaagg
     6601 attacatggc atgaatgcta ccatgtccaa atttattgtc agtaataatg tttttgatcc
     6661 catacgtgca gcagcaagtg cagcttctga accggcgtgt cctgcgccaa caacgatcac
     6721 gtcatacgca tctgcttcat aatgttccaa tcgtttgttc ctccttttat tttcctaaac
     6781 aaaattgact gaataattga gtgattagct catcttgtac actgtcgccg acaacttctc
     6841 ctagatagtc ccagcaacgc gtcatatcta tttgaacgag atccacaggc attcctgaat
     6901 caatacctgc aatgacttct tcaagtgaga gggaagcttt ttctaacaac gcgatatggc
     6961 gggtattaga aacataagta gcgtctcttt ctcctgtttc tccgctgaag aataaatcag
     7021 aaatagctga ttccaaacga tctagtccgt cgtttttagc tacggaaatt gaaaaaactg
     7081 gttcattttc gatcaatttc ttcaattttt cttgttccag ctgtgctggc aaatctgttt
     7141 tatttagaag aatgatccgt ttcaatccac ttgtcgcttc caataattgt tcatcttctg
     7201 ctgtcagtgg ttcgctttgg tttagaacaa gtaagatcaa gtctgcttct gctaatgctt
     7261 ttcggcttct ttcgaccccg atccgttcca ccacatcttc tgtttcccga attccagctg
     7321 tatcgattag cttgagcggt accccccgaa cattgacata ctcttcgatt acatctcgag
     7381 tcgttcctgc aatatccgta acgattgctt tttcttctct taacaaatgg tttaacaaac
     7441 ttgatttgcc gacatttggc cggccgatga ttgccgtact taacccttcc cgcagaacct
     7501 tcccttgctt ggatgtagca agtagcgctt ggattctttg ttggatcatc tgcgcttttt
     7561 caagcaataa cttcgtagtc aattcttcga catcatcata ttctggataa tcaatattta
     7621 cttctacttg tgctaatgtc tctaaaatct cttgtctcaa tgagcggatc aaagcagaca
     7681 gattgccgtc taactgatta agagctagtc ccattgcttt gtctgttttt gcccgaatca
     7741 aatccatcac agcttctgcc tgtgaaaggt caacacgacc attcaagaat gctcgttttg
     7801 tgaattcgcc tggctcagct aatcttgcac cttctcttaa caatagctgc aaaatttgat
     7861 tgactacaac gatcccaccg tgacaattga tttctactac atcttcccgc gtaaatgtct
     7921 ttggtgctct catcacggag accatgactt catcgacaag ctgattgctc ttgggatcaa
     7981 cgatatgtcc ataatggatc gtatgacttg gtacttctga taatcgtttg tttccagatt
     8041 gataaacttt atctgctagt tgcacagctt gatcgccact taaacgaacg atactgattg
     8101 caccttctcc aggtggggta gaaattgccg caatcgtatc aaattctaaa gtaatttcag
     8161 ccattttttc acttcctttt tcattttgcg cacaaaaaaa gtgcccactc caccctttat
     8221 gcacaataaa cggtgaactt cgcactttga ctgcttgttc ttgattaaat tctggtcata
     8281 gattatcaca cttgctataa ggaatcaagt gtttaaaaca attagatgaa gttgagcctg
     8341 ttctgcttcc attaccttat atttaattgt ccttggatgt ctctttgcgt tctttggttt
     8401 attcgaagag aagatactgt ataaacaagg ctttatcttt cttaaaaaaa acggtacact
     8461 aaatggtagc gctatctaaa ctatacactt ttgaaaggag aaaatatgtg agcccgttca
     8521 gatctgctgc attggaagaa gaaagtgacc ctcggatcaa cgatgtcgtt ttatctacag
     8581 ggaatatcaa ccagaaatat atcgtccgcg atatcgtttt tgttgtggaa tgcttagaag
     8641 ctgatttgtt tgacccatct tttcccaaag atgacctttt cttaacaacg aagaggaaat
     8701 taaagacgaa ggtacttgaa tatggtgcga atgcagtaat caactgtcat tttgagtatc
     8761 agcaaaaaaa acgcgacgga aagtattttc tggaactttt tgcttatgga acagtgatcc
     8821 aatttatcca aacaacgatt ggttaaatga aacagacaaa aaaagcggat caaaactgaa
     8881 gacagtttcg atccgctttt ttctatcaaa gttagtgact acttcatcgt atactctgat
     8941 aagaatgatt tctagtaaaa tatacttggt ttgaaaaact ttgtcaacgt gatttattca
     9001 aaaagtaatg gaatcaataa tattttttag caggttctac tactaaataa cgataaggtt
     9061 cctcaccttc cgaatgtgtt tttacatgtt catctttgct taatgcagca tggatttgtt
     9121 tacgttcaaa tgcaggcatt ggttctaaga aaacaggctg ccctgtccgt tttacttttt
     9181 cagccgtgcg atcagctaaa cgctgaatga tctcttggcg cttttcacgg taattgccta
     9241 cattgactac tacagacagc ttatttcttg ctaaacgatg gatgaagact tgtgccagat
     9301 attgcaatgc attcagtgtt tttccatgtt tcccaatcag tatgccttgc ttttgtgttt
     9361 ctaaatggaa aacaaccata ttatttgatt ctctttccat tttgacaaga gctggagcat
     9421 caagctgttt tgaaatttca gtaagataaa ctgccaattc cgttaaagct gcttcatcac
     9481 ctagctcact tacttcttct gttttttctt caagaatcgt ttcgttgact acctcgatct
     9541 cagctgttgg ttcttcttcc aaaatttctt ctacagtctg ttctactgtt tcagaaactt
     9601 tttcgctgat acttggctgg atcgaaagcc gtgcattctt tcgacccatt cctaggaaac
     9661 ctttttttcc ttcttccagt atttcgattt cgacttggtc tttggccaaa cccaaatcag
     9721 ccagacctag ttggacagct tcgtctattg ttgcagcttc ataaatcggc attagcatta
     9781 cctcccctat tatttccgtt ttttcttagg attcattgct ttcttaagag cacgttctct
     9841 ttcgcggatt ctccgtgctt cttcttcacg ctcttttcga attttgaaag ggttgttgat
     9901 cagcagcgtt tgtacaactt ggaaggcatt ggaaactacc cagtataatg aaagaccgct
     9961 ggctaaattg acacccatca ctaaaatcat tacaggcatc acgaaattca tgatcttcat
    10021 tgatgcattc gattcaattt gactcatgct agataaatac gtacttgcaa aagtaaagat
    10081 tgctgctaaa atcggcaaaa taaatgttgg atccgcgttc cctaagttca accataagaa
    10141 atgcccttgt ttcaactctg gtacacgtga aatagattgc cataacgcca tcaagattgg
    10201 catttgtact aataaaggaa gacaaccagc atatggattg acgccatttt ctgcatataa
    10261 acgctgctgc tcttctctta acttactttg tgtttccgga tctcttgaac tatattgttg
    10321 ctgcagtgct tttaatttcg gttgtaattc ttgcgtttta cgcatgctct ttgtttggaa
    10381 atgcatcaac ggcaatagga tcacgcggat gatcagtgta aataaaatga tccctatccc
    10441 tgcattacca aatgacaacg ccttgatcgc ctcagcaaag taataaacaa tataacgatc
    10501 ccaaattcct gtactctgtg cgctgacttc cccagttccg caaccggata agacgatgac
    10561 caaactaacg ataccggcca tcaaaagtaa acgtttgtat ttcttcactt actcttttcc
    10621 tctctgtcga ttatttttgc aagttttaag acgtggacta aattggagcg aacctcatca
    10681 taagtcaacc ccttcacact tggtctagca atcacaataa aatccaactc cggatcaatt
    10741 tcttctttta tagaataaac tgctgctcgg atttttcgtt tgacttcatt gcggtttacc
    10801 gcgttgccga ccttttttcc tacagataaa ccaactcgaa aatgaggctg tcccggtttt
    10861 tccaaacggt aaacgacgaa tttgcggtta gcaaaagaat ctcccgtatg gaacacggct
    10921 tgaaactctc gttctttttt tactcgatac gcttttctca ttagttttct ttccttttct
    10981 atctctcact tacgctcata atcataccat aattacgatt gtcctttcat catttcccta
    11041 aaaaagagta taaaaaaaac cactgaaacc ccagtggcct aagctgaaag aacttttctt
    11101 cctttgcgac gacggctagc taacacacga cgtccatttt tagtactcat acgtttacgg
    11161 aatccgtgaa ctttttgacg tttacgttta tttggttggt atgttctttt catatattcc
    11221 acctccaaaa tgttcttatc tattttataa acacagacat actttgatag tataacgaca
    11281 aagtagtgat tttgtcaata taaaatagaa gatcgattgt taaaacttat ccacaagatt
    11341 atttttttct atgggagtcc tatgtggaaa aagttatgca cagggattat ccacagataa
    11401 taaatggctg gttttacaca gaaaacacac gtgtaaaaaa agtaatccac aatcaggtga
    11461 tttcctgtgt attccgtctc ctaactattg gtatatctat attttttatc cacagatgca
    11521 agaggaaatc tattgatttt tacgagtttt ccacctgtgc attagtggtg tggaaaactt
    11581 ttttttgaca actgtgtttt tctctttttt ctttttgtcg attgtgtgga taattgtaat
    11641 taaaaaattt ttttcttcgg tttctgtgga aaactattga aaaaaatgct aaattagtac
    11701 tagttattca ctttttaatg aaggaggagg ccttatatgg tatccctcga tgctttatgg
    11761 aatgaattaa aagcaacata ccaaaaggat ttatcgcctg ctagctataa tacatggatc
    11821 gaaacagcga accctcgaac ccttgatcaa aaccagctcg ttgttgaggt tcctagcaag
    11881 attcataaag aatattggga aaaaaacctg gcgacaaaaa tcgttgaagt cggttatatg
    11941 ttatcaggaa atgagattat ccctcgcttt attactggcg aagaagcaga gcaagaagaa
    12001 gttatagaag aaaaaaatcc aaaagttgtg gcacctagtc cgctaaaaaa agccatgctg
    12061 aaccctaaat atacctttga tacgtttgtc attggtaaag gaaaccagat ggctcatgca
    12121 gcagcgctcg ttgtagcaga agatccaggt tctatttata acccgctctt cttttatgga
    12181 ggcgtgggac ttggtaagac tcacttgatg catgcaattg gtcatcaaat gctgcaaagt
    12241 cagcctaatg ccaaagtaaa atatgtaagc agtgaaactt ttgctaatga tttcatcaat
    12301 tcgatccaaa acaaaacagc agaagagttc cgtcaagaat atcgaaatgt tgatttactg
    12361 ctagtggatg acattcaatt ttttgcagaa aaagaagcta cgcaagaaga gtttttccat
    12421 actttcaatg ccttgtacaa tgaagggaaa caaatcgtac taaccagtga tcggttgcca
    12481 aacgagattc cgaaactgca agaacgcctc gtttctcgct ttgcatgggg gctgtctgtt
    12541 gatattacac cgccggatct tgaaacaaga acagcgattt tacgtaaaaa agcggcggct
    12601 gaacgtctag agatcccaga tgacacacta agctacatcg caggacaaat tgattctaac
    12661 attcgtgaat tagaaggtgc gcttgttcga gtgcaagctt ttgctgcgat gaatagtgaa
    12721 gatatttcga ctagtctagc tgcagacgca ctgaaaacgt taaaatcagg aaaaggacat
    12781 cctcaattgt caatcctgca gatccaagaa gaagtggcaa agtattatca catccaattg
    12841 aaagatatca aaggaaagaa acgcgtcaaa tctattgttg ttcctagaca aatcgctatg
    12901 tatttggcac gtgagctcac agataattct ttaccgaaaa tcggagctga attcggtggc
    12961 aaggatcata caacggttat ccatgctcat gaaaaaatcc agcagctgat ggattctagt
    13021 gtcagtatgc aaaatgaagt atcagaaatc aaaaactttt tactaaatta atttgtcgat
    13081 tctatcaact gaaaatagca tgtggataaa agaaaaaaac gttcaaaagt tatgcacact
    13141 ttttccacag ctgttttttc gtttctctct tacgtttttt gagttttcca cagaatcaac
    13201 atgccctatt acttttatta ttctttttaa ctaataataa ataaacaaac attcaaagga
    13261 gatacatcat gaaagttact ttaaaccgag ctagctttat gcaggaattg caaactgttc
    13321 aacgagctat ttcaagcaaa accacgatcc ctattttgac aggtgtaaaa atcacactga
    13381 cacaagaagg tttgactttg acggggagca acgctgatat atcaattgaa acttttttgt
    13441 ctgttgaaaa cgaaaaagca aatatgcaaa tcgaatctac tggttccatt gttttacaag
    13501 cacgtttctt tagcgaaatc attcggagac ttcctgaaga aacatttact ttagaagttt
    13561 tagaaaataa acaagtagcg attacttctg gaaaagcgaa ttttatcgta aatggattag
    13621 atgcagataa ctatcctcat cttcctgttg tcgaaagcca taaccagatg aaattacctg
    13681 tacacgtatt gactaaacta atcaacgaaa cagtttttgc tgtctcacaa catgagagtc
    13741 gtccaatctt gacaggtgtg catttcattt tatctgataa ttctttattg gctgtagcta
    13801 ctgattctca ccgtctaagt caacgcgtga ttccagtaga acaagcggct gatcattttg
    13861 atattgttat tcctggaaaa agtttgatcg aattatctcg ctcattaaca aatgaagaag
    13921 aaatcgtcga aatcagcatt atggaaaacc aagtgttgtt caaaacagaa acgatgtatt
    13981 tctattcccg tttgctagaa ggaaactatc ctgataccaa tcgtttgatt ccttcaagtt
    14041 ttaatacaga ggttgaattt tctgttccta gctttttagc ggcgatcgaa cgggcttctt
    14101 tactttctca tgaaggccgt aacaacatcg ttcgtttatc tattcgtcca gatgcggttg
    14161 ttttatacgg aaattcgcca gaaatcggga aagtagaaga aagcttgagt tatacagcaa
    14221 gcagtggcga tccattagat atttctttca atccggatta tatgaaagca gcgttgcgtg
    14281 catttggaga tatgagcatc aaagtgaaat ttatctctgc tattcgtcca tttacattgg
    14341 aaccaacgga agatggcgtt caatttattc agctgattac tcctgtacgt acaaattaac
    14401 aatgattttc attgttcttg aaaatttaat tgaaaagaaa tagaaaaaat aaaattttaa
    14461 acagaaggcc ctaaaatctc tt
//
LOCUS       DADGHT010000073        14129 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.074, whole genome shotgun sequence.
ACCESSION   DADGHT010000073 DADGHT010000000
VERSION     DADGHT010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.074"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(41..3694)
                     /gene="rpoC"
                     /locus_tag="JX887_002014"
     CDS             complement(41..3694)
                     /gene="rpoC"
                     /locus_tag="JX887_002014"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAX1257991.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(3773..7390)
                     /gene="rpoB"
                     /locus_tag="JX887_002015"
     CDS             complement(3773..7390)
                     /gene="rpoB"
                     /locus_tag="JX887_002015"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAX1257992.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8118..9086
                     /locus_tag="JX887_002016"
     CDS             8118..9086
                     /locus_tag="JX887_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1257993.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9104..10009
                     /locus_tag="JX887_002017"
     CDS             9104..10009
                     /locus_tag="JX887_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1257994.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            10006..10812
                     /locus_tag="JX887_002018"
     CDS             10006..10812
                     /locus_tag="JX887_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1257995.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10969..11937
                     /locus_tag="JX887_002019"
     CDS             10969..11937
                     /locus_tag="JX887_002019"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAX1257996.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12254..12778)
                     /locus_tag="JX887_002020"
     CDS             complement(12254..12778)
                     /locus_tag="JX887_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAX1257997.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13065..>14129
                     /gene="scm"
                     /locus_tag="JX887_002021"
     CDS             13065..>14129
                     /gene="scm"
                     /locus_tag="JX887_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAX1257998.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT         4001 a         3048 c         2787 g         4293 t
ORIGIN      
        1 gttgtgacaa taatttgtca caacctcttt tttaaaatat ctattttgtt tgattgttca
       61 ttgcgtcttc tgcagccatt tgcgcttcaa tatctgaaat actgtagaca ttttcgcttg
      121 ctacaccgac ttcttttggt tccatgtcac gataacgttg cataccagta ccagctggga
      181 tgatcttacc tataataaca ttttctttca aaccaagaag aggatctttc ttaccgcgga
      241 tcgcagcatc cgtcaagaca cgagttgttt cttggaatga tgcagcagat aagaaactat
      301 ttgtttctaa tgatgctttt gtgataccta gtaagacagg tcgagaagtt gcaggaacgc
      361 ctcctgagac tagcgtattg tagttttgat ctttaaagtc tgcgatgtct aataatgtac
      421 ctggtaagat atctgtatca cctggatcca ttacacgaac tttacgcagc atttgacgaa
      481 ccattacttc gatatgcttg tcgccgattt ctaccccttg catacggtaa acacgttgta
      541 cttcacgaag caagtagttt tcaacagata atacatcgcg aacttgcaac aattgttttg
      601 gatcgattga tccttctgtc aatggtgcac cacggtggat catatcgcct tctgctactt
      661 tcatacgtgc tgtataagga acagtatacg tacgtgtatc tgtttttcct ttgattgtta
      721 cttctttggt acgtgttgca ggatcttctg agatatcgat gacatcccct gttacttctg
      781 tgatcactgc ttgccctttc ggattacgtg cttcaaagat ttcttggaca cgaggaagac
      841 cttgagtgat atcgtctccg gcaaccccac ctgtatggaa tgtacgcatc gtcaactgag
      901 taccaggttc accgattgat tgagcggcga tcgtaccaac tgcttctccg acttcaacgt
      961 cagagccagt tgcaaggttg cgtccgtaac aatgtttgca gacaccatgt tttgtattac
     1021 atgtgaagac agaacggatt gtcactgttt cgacacctgc atcaacgatt tgttttgcga
     1081 tgtcttcgga aatcaattgg tttcctgcaa tgatcaattc atttgtttca ggatgacgta
     1141 cttctttacg ggtgtaacgt cccactaaac gatcttctaa tgattcgatg atttcatttc
     1201 cctcgcggat ggcttggatt tcaagacctc ggtcagtacc gcaatcttct tcacggatga
     1261 ttacatcttg ggccacgtca accagacgac gagtcaagta acctgaatcg gcagtcttca
     1321 aggctgtatc ggtcatccct ttacgagccc cgtgagttga gataaacatt tccaagacgg
     1381 atagtccttc acggaagttc gaaatgattg gcaattccat gattcgacca ttaggagcgg
     1441 ccatcaaacc acgcattccg gcaagctgtg taaagttgga aatgttacca cgagctccag
     1501 aatcagacat catgaagatt ggatttttcg cttccaaacc ttccatcagt ttttgttgga
     1561 tgctgtcttt tgcagcattc caaacagcaa tgacacgttc ataacgttcg tcatctgtga
     1621 tcagaccacg acggaattgt tttgtaatag tttcaacttg tttatgggca ttttcaatga
     1681 tttcttgttt ttcattcagt acactgatgt cagcgatccc tactgtgata ccggcatgtg
     1741 tcgaatgttt gtaccctaag tctttcatac ggtcaagcat cttagaagtt tcttttactt
     1801 tgaatcgttt gaagacttct gcgatgatgt ttcctaagtt tttcttcttg aacggtaata
     1861 ctaattcttg ctctttgata tgtgcaggaa tatcagtacc agcttcaaca aagtatttgt
     1921 ccggtgtttg gacggtcaag ttgaagtctg ttggttcatt cagataaggg aattcaggag
     1981 gcatgatctc gttgaagatg atcttaccaa ctgttgtgat catcgtacgt tctttttgcc
     2041 attcagtaaa tggtttttca cctaatgagt tagggttcac accgatacgt gaatgtaaat
     2101 gaacatatcc gttgcgccat gcgataacgg cttcgttttg atctctgaag accattcctt
     2161 cgccttcgcg tccttcttct tccattgtca agtagtagtt acctagaacc atatcttgag
     2221 aaggagtaac aactggttta ccatctttag ggttcaagat gttttgagca gctaacatca
     2281 acatacgtgc ttctgcttgt gcttcttcat tcaatggaac gtggacagcc atttggtctc
     2341 catcgaaatc ggcattataa gcttcacata caagtggatg caaacggatt gcgcgtcctt
     2401 gtactaaaac tggttcgaat gcttggatac caagtcggtg aagcgtaggt gcccggttca
     2461 gcaatactgg gtgttccttg attacgtctt ctaaaacatc ccatacttcg tcttcttgac
     2521 gttcgatttt acgtttcgca tttttgatgt ttgaagctag ttcgcgttga acaagctcac
     2581 gcatcacgaa tggtttgaat aattcaatgg ccatttcttt tggaagtcca cattggtaca
     2641 tcttcaagaa aggtccaaca acgataacgg aacgacctga gtagtcgaca cgtttaccta
     2701 gcaagttttg acggaaacga ccttgtttcc ctttcaacat atgagaaaga gatttcaatg
     2761 ggcggttacc tggtccagta actggacgtc cgcgacgacc gttatcgatc aatgcatcta
     2821 ctgcttcttg cagcatacgt ttttcatttt gaacgatgat tccaggtgca ttcaagtcta
     2881 acaaacgttt caaacggtta ttacggttga ttacacgacg gtaaagatca ttcaagtcac
     2941 ttgttgcaaa acgtccacct tctaattgaa ccattgggcg taaatctggt ggaataacag
     3001 ggataacgtc cataaccatc cagcttggtt gatttcctga agcgcggaat gcttctaaaa
     3061 tatccaaacg gcggattgca cgtgtacgtt tttgtccttg tgcagatttc aattcttctt
     3121 tcaattcggc tgcttctgca tctagatcaa cattatcaag taattgttta atcgcttctg
     3181 cacccatagc agcttggaat tcttgtccat attgttcacg tttttcgcga tattcgcgtt
     3241 ctgtcaacaa ttgttttttc tctaaattcg tatttcctgg ttcgatgact acatatgaag
     3301 caaaataaat gatttcttcc aaagcgcgtg ggctcatgtc taatacaaga cccatacgtg
     3361 aaggaatccc tttaaagtac cagatatgtg aaacaggagc tgctaattca atatgtccca
     3421 tgcgttcacg gcgaactttc gaacgagtaa cttccactcc gcatcgatca caaacgattc
     3481 ctttataacg gatacgtttg tattttccgc aggcacattc ccagtctttt gtaggaccaa
     3541 aaatccgctc acagaacaac ccttcgcgtt caggttttaa ggtacgatag ttaatcgtct
     3601 caggtttttt tacttcaccg taagaccagc ttctgatttt ttcgggagaa gccaaaccta
     3661 tttgcatact ttcgaattta tttacatcga tcaaaagggg ttccctccat ttcatttaat
     3721 ggcaaaccgc aagacggctg atcttcgacc gccttgcagc tcatagaccg gattagtcta
     3781 aattatcttc tgcggtttca aagttttgga tgacatcgtc tttttcatct tccacttgtt
     3841 cagcagcttt cttttctaat tctttggcag tttgctgttc ggcaaatttt gtcaaagcat
     3901 caacagtgat caaatcgtcg tcttcatcgt ccatgtcgcg aagttcgatc tctgtttctt
     3961 cgatatccaa gacacgcatg tccagaccta gtgattgcaa ttctttcacc aatacgcgga
     4021 atgattccgg tacacctggt tttggaattg gttcaccctt gacgattgct tcgtatgttt
     4081 tcacacgtcc gactacgtca tctgatttgt atgtcaagat ttcttgtaaa gtataagccg
     4141 caccgtaagc ttccagtgcc catacttcca tttcaccaaa acgttgtcca ccaaattgag
     4201 ctttacctcc caatggttgt tgtgtaacca atgagtaagg tccgattgaa cgtgcatgca
     4261 atttgtcatc gaccatgtga gcaagtttga tcatgtacat cacaccgaca gacacacgtc
     4321 catcaaatgg ttcacctgta cgtccgtcgt acagaacagt tttcgcatcg ctggccatac
     4381 cggcttcacg aactgtttcc catacgtctt catcacttgc accatcaaat actggcgttg
     4441 ctacgtggat acctaactga cgtgcagcca tacccaagtg taattccaat acttgcccga
     4501 tgttcatacg tgaaggcacc cctaaaggat tcagcatgat atcgattggt gttccatcag
     4561 gtaggaatgg catatcttct tccggcataa tacgggatac aaccccttta tttccgtgac
     4621 gaccggccat tttatcccct tcatggattt tacgtttttg aacgatataa acacgaacta
     4681 acatgtttac gcctggtgac aattcatctc cagcttcacg agtaaagatt ttcacatcgt
     4741 gaacgatacc gccgccgcca tgtggtacac gtaatgatgt atcgcggact tcacgagctt
     4801 tttcgccaaa gatcgcatgc aatagacgtt cttctgcaga taattctgtt accccttttg
     4861 gcgtgacttt ccctacaagc aaatcgccat cttggacttc tgcaccaata cggatgatac
     4921 ccatttcgtc taaatctttt aatgcgtctt ccccgacatt agggatttcg cgtgtgattt
     4981 cttcaggtcc taattttgta tcgcgggctt ctgattcata ttcttcaata tggatagaag
     5041 tgtatacgtc atcttttacc aaacgacggc tcatgatgat cgcatcttca tagttgtacc
     5101 cttcccaagt catgaaacca actaaaacgt tttggcctag agccatttcg ccttgttcca
     5161 tagatggtcc gtctgccaga gtatcccctt tttcgacttt ctcacccaaa tgaacgattg
     5221 gacgttggtt gtagcttgtt ccggagtttg aacgacggaa ttttgttaca tcgtatttat
     5281 ctaatgcacc gttgtcgcgg cgtacgcgga tttcagaagc atcaacgtat tcaacgacac
     5341 catcatgttt acataacaaa gcagctcctg agtcatgcgc tgatttgtat tccataccag
     5401 taccaaccca tggtgcttga ggattgatca acggcactgc ttgacgctgc atgttggcac
     5461 ccatcaaggc acggttggag tcatcgtttt ccaagaaagg aatacatgct gtcgcaacgg
     5521 caactacttg tttaggtgat acgtccatgt agtctacttt atcaatagat acttctaagt
     5581 tttcactttg agcacgagcc ataacaacgt cttgagcaaa tgttccatct tcattcaatg
     5641 ggctgtttgc ttgggctacg atgtaatggt cttcgatatc agctgtcaag tagtcgattt
     5701 ggtcagtaac acgacctgtt tcacggtcta cacgacgata aggtgtttcg ataaatccga
     5761 atttatttac tttcgcataa ctggacaaac tattgatcaa cccgatgttt gggccttcag
     5821 gagtttcgat cggacacata cggccatagt gggagtagtg aacgtcacga acttcataac
     5881 cggcgcggtc acgagtcaat ccgccaggtc ctaaggcgaa aagacgacgt ttgtgtgtca
     5941 attcgccaag agggtttgtt tgatccatga actgtgacaa ctgagaagaa ccaaagaatt
     6001 ctttgatact tgccacaact ggacggatat tgatcaattg ttgaggtgtc aatgtttcag
     6061 tatcttggat cgacattctt tcacgaacca cacgttccat acgtgctagc ccgatacgga
     6121 attggttttg taaaagttca ccgactgaac ggatacgacg atttcctaag tggtcgatat
     6181 catcgacatt gccgatacct tccatcaagt tcaagaaata gctcattgaa gcaatgatgt
     6241 cggctggacg aaccgttttt acagctgctt ctggatagcc gtttccgatc acgtttactt
     6301 cacgttcagg gtctcttggt gaaaatactt tgatgacttg gacagtcatt ggatctgtga
     6361 ccacaccgtc ttctgatgga tagtaagtca ctgaatttag gccattatca atgaaaggag
     6421 ctagtgtttc catgacttgg tgagtcagaa ctgttccttt ttcaacgatg atctcgcctg
     6481 tttctggatc aactaatgtt tcagctaatg tcagattcaa tagacgtgtt ttcaaatcta
     6541 attttttgtt tactttgtaa cgaccaacgt ttgctaagtc gtaacgtttt ggatcgaaga
     6601 aacgagcatt cagcaagtta cgtgagctgt ctgctgtttt tggttcgcct ggacgcaaac
     6661 gttcgtaaac gtctttcaaa ccttcttctg ttcttgagtc gcttgcgttt ttatgcaagt
     6721 ctttttcgac tgtattgcgt aatgtttcgc tgtcgccgaa gatttcaaag atcgtatcat
     6781 cggaaccaaa tcctaacgca cgaactaata cggttaaagg aatcttacgt gtacggtcga
     6841 tacgtacata agagatgtct tttgcatcag tttccatttc tagccaagct ccacggttag
     6901 ggataacagt agaaccgaat ccttcttttc cgtttttgtc gacttttcca tggaaataga
     6961 cacctggtga acggactaac tgagaaacga ttactcgctc tgccccgttg atgatgaatg
     7021 ttccttgttc tgtcattaat gggaaatcac cgaagaatac ttcttgtgct ttgatttcgc
     7081 cagtctcgcg gtttgtcaaa cgcaatgtta catgtaatgg tgcagagtag tttgcatcat
     7141 gcgcacgagc ttctgctact gtatactttg gttctttcaa ttcataatct acaaattcca
     7201 aagatagatt gccattgaag tcatcgattg gcaaaatgtc ttcaaacatt tctctaagtc
     7261 cctcatctaa gaaccattgg taagagtctg tttgaatttc gatcaaattt ggtaattcca
     7321 acacttcact gattcttgcg aaacttctac gttcgcgatg ttttccgtat tttactacgt
     7381 gtccagccaa gctcttcacc cctctaaaat gtcattcaaa aagactaccc gatcaattgt
     7441 tacaataata tttcaaatat tatttttagg taacaacaga cattttttgc ggcttttagg
     7501 caaaaaaaaa ccaaaaatag aacattctct tgaaacctta cttcgtgagc ttctactttt
     7561 gtttccttat attaaagccg aaacggacaa tatttcgttt ctgccttttc ttcatcagat
     7621 agtttttgca acttcatata ctacacttat tttctataaa agtcaacact tcctggcgtt
     7681 tcttctgctt tttcgcaaca ttttcttaat gttttcaatt ttatgttttc aattatctga
     7741 caattcttaa ttgacagacc tttttatctc ggttatactt tagaaaattc attttgtgga
     7801 ggaacttcta tgcgaaccaa catcaaccaa atcgcaccaa cacaactgaa taacttttac
     7861 tttagctact ttagataggt ttgtattcat catgatggat acaaacgtta aacgacagtt
     7921 tgtatctatg atggctaaag aactttgtat tgcagcaaaa agccacgtag acaaaatgct
     7981 aagtggctga gcagtgaaaa tacaaagtaa aagtatcaag cattctactt tttcaattta
     8041 ttttccgact tttcaatcca tttggacatt ttgtctgaat ggattttttg tttcccaaaa
     8101 ttaaggagga aaaagaaatg aaaaaaaata taatcatcgg attaggcgct gccctgctac
     8161 tagctttagg aggttgcgca caaaaagaca attccgcaga ggcatcagat ggacaaaaaa
     8221 caattggcgt attgcaactt gtacaacata actcgttaga tgctgcctat aaaggattca
     8281 aagaaggatt agcagaagaa gggtataaag aaggcgataa tctaacaatc gattatcaaa
     8341 atgcccaaaa caatcaagac aacctgaaaa gtatgagtga gaaactcgtc aaagaagatc
     8401 ctgatttgct acttggaatc gccactccag cagcacaatc tttattaaat gaaacaacca
     8461 ctatcccgat gactgtcaca gcggtcacag acttggaaca agcccattta gtcacatcca
     8521 atgaaaaacc tggcggcaat gtgactggca cgacagatat ggtgccaatc gaaaaacaaa
     8581 tcggcttact gttaaatatc gtgccagacg ccaaaacaat cggcatcatg tataacaacg
     8641 gtgaagcaaa ctctaagatc caagctgatt tggcagaaaa agaattgaaa aaagcgggcg
     8701 tcaaagtcaa agtactgaca gcaaattcca caaatgatgt ccaacaagtg acgaaaagtc
     8761 tagctaaaga tgtagatgga atctatattc ctactgataa cacgttcgca agtgcggcaa
     8821 gtgttgtcgg tgaagtcgca aaagaaacaa aaacacctgt cgttgctggc gcagttgatc
     8881 aagtcaaaga cggcggtcta gcaacagtag gaatcgacta cgaaagcttg ggcaaacaaa
     8941 cagggatcat ggcagcaaaa atcttagacg gcaagaatcc aagtgaactt cctgtcgaaa
     9001 cagcgaatga tttggaactg tatgtcaata aagacatggc caaagcatta ggcatcaatc
     9061 cagacagcat caaagaagct gaataaaaca caggaggatt ctcatgacaa atttgctctc
     9121 tcttttctta tcatctgcat cgcaaggggt cttatgggcc ctacttgcga ttggtgtata
     9181 cgtcactttc cgtatcttgg acattgccga cttgactgct gaaggaagct ttcctttagg
     9241 tgcagggatc gcggcagtaa gtattacaaa tggctatcat ccattgacag cttgtcttct
     9301 aggcttttta gggagtgcgg cagcagggct tgtttccgga ctgcttcaca caaaattgaa
     9361 aattcccgcc cttcttgcag ggatcatcac catgactggt ttatattctg tcacatcccg
     9421 tgtgatgggt gcgccgaaca tctctttatt gggtcagcca acgatctttc attgggtcga
     9481 gtcattcggc ataacaaaag acaacgctgt actgatcgtc ggtctgcttt ttgctttgat
     9541 cgttgtatgt ttacttgttt tgttcttacg tacagaaaca ggacttgcta ttcgtgcaac
     9601 tggcgataat ctggcaatga gcgaagcaaa cgggatcaac acagataata tgaagatcat
     9661 cggttatatg atttctaatg gatgcattgc tctttctggc tccttgcttg cgcaaaacaa
     9721 cggctttgct gatttaaatt ctggtattgg aacgatcgta attggacttg cttctattat
     9781 catcgcagaa gttttgttac gtaaccagcc actatttctc cgtctcttga ctgtcgtttt
     9841 aggtgcggtc atttatcgtt ttattttagc gttagtcttc gaactgaatg ttgaaccaag
     9901 tgattcgaaa cttgcttctg ctttcgtgct agtgatctgt ctttctttcc cgcagatcca
     9961 gcaaaaattc catttacctc aaaaaaagaa aggcggtagt gtcaaatgaa tgacgtctta
    10021 acattggaaa atctccatca tacctttgaa aaaggaacga tcaacgaaaa tcatgtcctg
    10081 aaaggcatta atctttcctt agatcccggc gacttcgtga cgatcatcgg tggaaatggg
    10141 gctggtaaat ctactttgct gaacagcatc gccggtacat tttctgtcga tcagggtcaa
    10201 attttattga atggaaaaaa tatcacgaaa aaatctgttg tcgaacgttc gaaatccatc
    10261 agtcgcgtat tccaagatcc taaactaggg acagccgttc gtttaacggt agaagaaaat
    10321 cttgctcttg ctatgaaacg aggaaaaaaa cgcggcttct tccgtggtgt caaaccacaa
    10381 gaccgaacat ttttcaaaga ccagctggtt cggctaaatt tggggttgga aaatcgttta
    10441 tcctcagaaa tcggtttgct gtctggagga caacgtcaag ctattacgtt attgatggcc
    10501 acattacagc gtccagaact gatcttatta gatgaacaca ctgcagcgct tgaccctgct
    10561 acttccaaaa cggtgatgga attgacagaa aagctgatca ctgagcagaa tctcactgct
    10621 tttatggtca ctcatgacat ggaagacgcg atccgctatg ggagtcgact gatcatgctg
    10681 catcaaggaa ggatcgtcgt agatatccag caagaggaaa aacagcagct cacagtgccc
    10741 caattattag cgttgttcaa acaaaacagc ggcacggcat taaaagacga tcaagtactt
    10801 ttatcttcat aatcagaaag aggatgggac aaaaaatgaa cgcccaccct cttctttttt
    10861 ctctttcctt ctttcgtttt tgctttatgt atcaaccgtt gtttcttcga aaactatttt
    10921 gttctctcct tcttcctgat agaatggatg ggaaaggagc ttgatgccat gacaacgaaa
    10981 gacaaggtac ttcaattatt gaaaaagaca ccagattttc tttccggaga aaagttggca
    11041 cagcaactgg aagtttcccg gacaagtatt tggaaagcca tcaaagaatt ggaaaaggca
    11101 ggctatcgtt ttgagcacgg gcctacaggg tatcgttacc tgccctctga cgtactagat
    11161 gcaaaagaaa tccagcaaga gctacggtcg tttattcctg atttgaaagt acaaacgatg
    11221 atgacttctg aatctacgat gaaagatgcc aaactggcag cagctcaagg agattctgtt
    11281 tcgaagttat ttgttgctga tacacaagaa caagctcgtg gacgttttgg acggcctttt
    11341 ttcgctgaac ctggacgagg aatctacatg agtctcttgc tccatccaga caaacggttt
    11401 gatgaattgc ctcaatatac gatcatcgca gccagtgcct gtgtgaaagc cattgaatct
    11461 gtaaccggtc gttctgcttc gatcaaatgg gtcaatgata tctacatgga tggaaaaaaa
    11521 gtctgtggga ttttatctga agcagtcagt gatatggaaa gcggcaggat cagtcatatc
    11581 atcattggga tcgggcttaa tttttctgtt cctcaaaatc attttccagc tgatctccaa
    11641 gaaaaagcca tctctgtctt tcccgacgga caagctagtg tcacaaggaa tcagctaatc
    11701 agcaaaatct ggcaagaatt gttcacttat ctttctcacc cagaaaaagc gttggacttc
    11761 tataaagaaa aatcattcgt attgggaaaa accgtgtcgt tcaatcaaaa aggaacgact
    11821 tatgtcggtc ttgcaaaaga aatcggtgat catggcgaac tgatcgtcca aacaaatgaa
    11881 cagaagatga gtttgtcttc tggcgaaatc agtctcacat ctatccgtac gcaataatta
    11941 tcagatttca caaaaggaca cctgatctca tacagtgtcc ttttttctga attctcttca
    12001 aaagactctc cttattctat cagctgacag tttctctatc ctctagaaaa aggtattcta
    12061 aaaatatcta taaagcatgg tacactttct ttaaatgaat caatgcaaaa aacaagagag
    12121 tcatcagttt acacgatcaa aagagatagc aggccgcttc ctttttcaat cttatagata
    12181 gaccatgggt aacgataaaa acaaaaaaga acttgcgact tattttgccg taagttcttt
    12241 tttagctagt gccttaatct cttaatccca acaaacgtct cgcatagatc acctgaccag
    12301 agtgcatagc agcatcatca ataatagaaa cgagacgcat tcctcgtgtg actggtggtg
    12361 tccagttctc gtcaattact tcatctagct cggaaggttc cagccttctt aagtaagaaa
    12421 tagcaaaatc agcagctcct cgcaagtatc ctagcagatc ttctatttga ttagcttgga
    12481 tctgctttgc ttgttccaga ctatgcttcc aatcttgttc gttatctgct atcgtcatcg
    12541 gaaaccggct ttcccagtct tgactatgcc aaattggaga agttcctgct aaatcagcaa
    12601 tctggaaatc taattctcga gcggtatgcc aagccagcca agtcattgat ttgatctgcg
    12661 gggctctatc ttccactgga aaacgattgg cctcctcaat agagacgcct tcaaacaaac
    12721 gttcaaaccg atcgtatgcc cgatccacac tctcgcatag catatctaaa taatccattt
    12781 attttcctcc tttttattta tcctacttac tttttcctaa ttctaggata cctacttata
    12841 tgttactaca cacccttatt ttttacactt taacagtcac catcatcaat agtttggaga
    12901 ttgaaagaaa aagatagtgt cgaactatca attgaacaag aagcaacaat atgaacgttt
    12961 cattaatatt ctttaaataa acaatgattt ttcaaacgaa cagtttaaga ctaggagaaa
    13021 aagagtataa taggaaaatg tttgaaagga aaggaagggg aaaaatgaaa aaaagggcaa
    13081 gtttactagt cctagttgct ttgttgttca atatcttttc gtatggtgtg gccgtttcag
    13141 cggaaacata cattcctaaa gaccctggga atatttataa tgatctaact ggtaactatg
    13201 gcttgttagg aattgctagt caattccacg tatttgctaa aaataagaca actgtgaatg
    13261 cacatacaga cggaaatata gcaacacatg aacttgatgc aaaaaataat tttggtacag
    13321 agcttcatga aggtttattg aaccaagaaa taaattatat acaaaaaact gattctttcg
    13381 ctaattcttc aggcatacct acaggtagca caagaatgaa taaatttgtc gttggcagta
    13441 acgtggatgt agcacttcaa gatggtcatc ctacagtcaa tggatccagg cttgatcact
    13501 taactccaga tgatttttat aaagatcgtg ctgggcatga atatattgat ttcgagcagg
    13561 aatttgctaa attgaatgta gcagcaaatg atcttgcaac gatcactcca gctaaaacat
    13621 atactgctgc agattttcca gacatgaaca atcggacaat cgatttaact gatttatcag
    13681 ataccgggtt tttattggta aatatcgatg cagaagtgtt aacgatgaat acgccacttc
    13741 aaatcattaa tccaaatgat caagtagttg tatttaatgt catcaacagt tcttctgcat
    13801 tgaacgtaca gtcaccaatc aaatacaatg atcgttcaaa tcatgaaaca gaagattttt
    13861 cggatgcgaa tatctcttgg aattttggaa atgagatgac tgatttgaca atcagtgctc
    13921 cttttcaagg aacaatcctt gcgcctaatg ctactatccg cattactcaa aaccaagacg
    13981 gaacgattat aggaacaaat gtgattttag atgcagctac caatcgttgg gatcctaacg
    14041 aaatatttat cagcgacaat ggtacagata cgacagacac aagcgacagt acagatacat
    14101 ctaccacaag tgatagctca gattcatca
//
LOCUS       DADGHT010000074        14056 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.075, whole genome shotgun sequence.
ACCESSION   DADGHT010000074 DADGHT010000000
VERSION     DADGHT010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.075"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(143..1345)
                     /locus_tag="JX887_002022"
     CDS             complement(143..1345)
                     /locus_tag="JX887_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1257999.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1348..1542)
                     /locus_tag="JX887_002023"
     CDS             complement(1348..1542)
                     /locus_tag="JX887_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAX1258000.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1589..2437)
                     /locus_tag="JX887_002024"
     CDS             complement(1589..2437)
                     /locus_tag="JX887_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HAX1258001.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2642..2992)
                     /locus_tag="JX887_002025"
     CDS             complement(2642..2992)
                     /locus_tag="JX887_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258002.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3587..4033
                     /locus_tag="JX887_002026"
     CDS             3587..4033
                     /locus_tag="JX887_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAX1258003.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            4657..5649
                     /locus_tag="JX887_002027"
     CDS             4657..5649
                     /locus_tag="JX887_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1258004.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5665..6549
                     /locus_tag="JX887_002028"
     CDS             5665..6549
                     /locus_tag="JX887_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1258005.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6598..8205
                     /locus_tag="JX887_002029"
     CDS             6598..8205
                     /locus_tag="JX887_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAX1258006.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8206..9690
                     /locus_tag="JX887_002030"
     CDS             8206..9690
                     /locus_tag="JX887_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAX1258007.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9867..10859
                     /locus_tag="JX887_002031"
     CDS             9867..10859
                     /locus_tag="JX887_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1258008.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10911..11780
                     /locus_tag="JX887_002032"
     CDS             10911..11780
                     /locus_tag="JX887_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1258009.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12200..13765)
                     /gene="guaA"
                     /locus_tag="JX887_002033"
     CDS             complement(12200..13765)
                     /gene="guaA"
                     /locus_tag="JX887_002033"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAX1258010.1"
                     /translation="MSSPTRFDEEPKIIVLDYGSQYNQLITRRIREFGVFSELMSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGK
                     VKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCP
                     IASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGK
                     FGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(13820..>14056)
                     /locus_tag="JX887_002034"
     CDS             complement(13820..>14056)
                     /locus_tag="JX887_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1258011.1"
                     /translation="ETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNGVTEGL
                     NNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         4303 a         2380 c         2905 g         4468 t
ORIGIN      
        1 ttgaaaaacg ttgatttatc ggcattcccc atccatatta tatttacgtc ttattcccac
       61 tcaatatgag tagcctcgta aagaagctat tatatcagtg ctttttcagc ctattcctca
      121 ttttggtagg gaaatggtag ggttagattt ttactgcttg atttccatta aagtttgcaa
      181 ctttagattt tgttgcacag gtaaatttaa tgtttcctgt catttgttct gcaattcctt
      241 catcattacg gctccataga tgagcgtagt gctttaaagt gatttcaggg ctagaatggc
      301 ctaaccgttg cgacacgacc agaatgtctg cgttaaactc attgattagg tagctaacat
      361 gagaatgacg taatcctttt ccttgtatta ggggtacctt agctagtttg gcataacgct
      421 gaataattcg ttgaacagtt gaacgataga gtgggaggtc agtgtagcta agaataaatt
      481 gttctacacc atgatttttt tgaataactt tccacttttt tagcacttca attgtatcat
      541 cgtccagaga aatgatccgc aagccgcttt cagtttttgt gtaaggtttc cgaataaaat
      601 ctttttgatt tgtcatttcc aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca
      661 cgtcattcca attaagtgct aatccttcgc ttacacgaac accagtcatg taatatagcc
      721 agatcattaa aaaacacata tgttcgtaga aatcatcttt ataaattttt gccaaaactt
      781 cttcaaattc ttcttttgtc cagtaaggaa cgattgattt tccttttgga attgcttttg
      841 ttcttttgga aatattctca ttcagaaatt gcagggtgac cgcatagtct aatgatttac
      901 gaaacatacc gtacataagt gaactgtatg cttgtgagta tccgctatcg ttcaataacc
      961 aaattcgata attttcacaa tctcgcacat tgatttcacg aagcttctta tcaccgaaaa
     1021 attcagtaat ctgaatcaat ccacactcac gagaactcca agtacttttt tgtacgctag
     1081 ctttgtagtg tggaacgtaa gactgctcca taaattcttt gtaagttaaa tcataattcg
     1141 caaatccatt tacaaccatg tattcatttt ttatacgcat gacttctttg tgtgcttcac
     1201 gagctgatga gaatcgtttt cctagagaat cttttgttcc tttcttctgg atcctctttc
     1261 cagtcacttg atctgttcct aactcaacta gataagaaaa gcgaccattt ttatcttgat
     1321 acacacaagg gtattttgtt ttcatagtta ttcctcctgt gaaagaggaa cacctataat
     1381 ttcttcaatt acttgtcggg gtactacccc aactctttta ttattataat atggatatcc
     1441 ctgatttacc attcttgttt ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa
     1501 tcctagagcc tctaaatctt ttcgacaaat tgtatttttc attgtataaa ctcactttca
     1561 aagaaaacac tatcattggg taatagtgtt atttctttat ttttgtataa tgaacggtac
     1621 tttcttgaaa atccatcact tgttcaggac ttcccaactc atttaaagct aaagcattgt
     1681 aaaaaaatgg acgtctaact atatattcgc ttgtatatag tatatcttga ttcgtggaat
     1741 catagggttt ctttaccatc tttttggtga cagttggtag tttgagattc cgggacttga
     1801 aaaaagcttt tttcttatgc tctttcaatt ccagctcttt atcgaaatat ttgctgatat
     1861 agcgcccgcg attttcgata ctgtctacat cgatcttgtt gatcttaacg aaaccctgac
     1921 cccaaatcgt agttaaccgg ttaaatgaga taaaggggaa atcaaacaag ataatatggt
     1981 agtggattgc accgcgttgc tgcttttccc acgtggcgag atactttaaa tttgcttttt
     2041 tagttttata gaggtcataa ttcagtcgtt tgataaattt tttaaattca ttatttgcat
     2101 actcaatgtc ttgaatgttt tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa
     2161 aattcgtgtc tacaaggcgg gcaatctcaa atcgcatact ttgataatgt ttctgtttgc
     2221 gttttaaact gtcatattgt ccttgagcgg ataattcatc atagtttttt cttttttcaa
     2281 gagtaatatc attttcataa atccaagcta atttttgttt tcgttccaga tttacttcgt
     2341 tttcgatcgt tttacgtttg ggagtaatga ttgcttcata atcataaatt tcaatatacg
     2401 tgggagtttc aatgattttc tgattataag cttgcaaaaa tcatcactcc ttgttgcgta
     2461 ttcgattgtc aaagaaccag tcattttctc ctgatgttga tctataaatc aagttaaggg
     2521 ggaaggcctg cgtagcagcc cttctagcct atggggtgtt gggcggtctt aacggacaga
     2581 aacggctctg tgggcgctgc cccgccgttt cgtcctaacc acccaacact ccatagtata
     2641 gttagttttg tgtagtggta ccttgttttc tgggaatcaa agttgccgta tcagcggttg
     2701 ccgataaccc ataactgaca aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat
     2761 tggtaaatgt aattatggct aaaccttgtt gggtaagttc ttccggcgtg atcacaggat
     2821 gttcagattt gactttgaca ctgatttttt cgtagcgaag ttttggtagg atacattcgt
     2881 agctccaacc tagaatttcg ccctcctttt gccagcgagt gacattgacg acttggtatt
     2941 ctttttcgag tgtttctttt ggtaaactga gatcggtaat ttttattggc atcacaattc
     3001 tcctttttta tacgaaagtt tatacgattt gattaaaaaa tatagatggc catctacgac
     3061 ttgtattata tacgagaact tatacgtagt caagagattt tctaaaaaaa tatatacgat
     3121 tttttatacg agtgttataa tgaaaaaaat gataaggagg aatttgaata tgtttggttt
     3181 agtacaacct aataaagtga aggtgggcca acgaatcaaa gaaataaaag acggaatgtc
     3241 tctctctttt acagaattag ggaatcgatt aggtttaaaa aagccgacga tcagttccta
     3301 cgttcaaggc tatgcgttgg ctcctaagag tgtgatcaac caattatcta gtatcagcgg
     3361 aaaacctgtc ggctggtttt attttgggca tgtggaagaa tatatccgag agtatttgtt
     3421 tctcattggt cagaaaaaaa tagtggacga ttatcctgaa atcattgaga aaataaagca
     3481 agaattttat acgggcgagt tcaaaaatcc tgcttgggag aatgagctag gctatccttt
     3541 ggaggaattt atccaagaat gttttgtaga atattcgagt gaaatcatga aggactatgt
     3601 cgtacagatt acgaaagagg tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa
     3661 agcaaaagaa gaagctgtca cgattctttc atctgggatc attgactata tcgagatgag
     3721 tggtgagatc aagtatggag agaaagatcg cattgcgaaa atggtgaaag aatcaataaa
     3781 aacctttgat gtgaaacaag acctgacatt taatgattcc tatttgattg gaaagttgat
     3841 caatattctt ggtacagatg aagatacgga gctgtttctt tcttctttat caatgatatt
     3901 tactgataag catttttcca ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc
     3961 gatgcgacca gcgttaatca aactctatcg ggagaaaaca ccagatgaat tttatgattg
     4021 gtttgagaag taaaataaga aaagtggctt agattacaag ttggtgaaaa aatttttttc
     4081 agcataacat cagtaatcta taaaggggtt gttgattata ctgtagaagt taagtactca
     4141 agagattttt tgtacgtaaa caaagcaaaa aagggtgcag tttcactaga aaatgtactc
     4201 ttttttgtga tttttcttag ttatagagtt tttttgaaac tttaaaaatg agaaaacata
     4261 ttgattttaa agagtgtaga catagcttct tttgctaaat agattaaact tactggtgag
     4321 tggtcttgaa catactttta aatcacattt tactgagttt tattggattt tataattcat
     4381 tggaaacctc gtacttaatc tgtttttatc tatcgactag aatctgtata tattccagct
     4441 atcaatgagg ccgcagaaaa gggtgcttaa aaataatctg ttgtttaaaa tattattatc
     4501 agaatactta gatacaaaat tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg
     4561 atatggtaat ctataaacga aaatagtggt aacgtttcca aaatgcatct tcgttaaatt
     4621 tttatttttt taaacgaaaa tggaaacgtt tctaaaatgt attgggagga gattgaattg
     4681 gaaaagacat tgggaccagg tggtgagata agggcggtac aacgggataa aaaaaatatt
     4741 tcgaagtggg aaaaattaaa gaaacagttg cggcgtgata agtggatgta cttgttgctc
     4801 ttaccaggta tcatcatgac gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt
     4861 gcatttaaag actataatcc tatgctagga attttggaaa gtccttgggt aggactagat
     4921 cactttaggg aatttatcag ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa
     4981 attagtattt atggtttatt gttaggtttt tttccaccaa ttattttagc actgagcttg
     5041 aatcaaatta tcaataaaaa aataaaacag aaaatccagt tgattctata tgcgccgaat
     5101 tttatctcag tagttattat tgtggggatg ctgtttttgt tcctatccgc aaatggacct
     5161 attaatgggt tagtagaaaa ggttacgggg caaccaatta tgttcatgtc taatccagct
     5221 tatttcagaa cgatttatat tttatcggga atttggcaag gaatcggctg gtcatccatt
     5281 ctttacaccg caacgctggc gggagtcagt accgatttat atgaggcagc aaatatcgat
     5341 ggggcaaata ttttacaaaa gatttggcat atcgatttgc ctgcattgag gcctgtgatg
     5401 gtgatcagct tcatcttggc cgccggcggt attatgaatg taggatatga aaaagcctac
     5461 ttgatgcaaa cttcaatgaa catccctgcc tcagaaatca tttccactta tgtatacaaa
     5521 gtcggcttgc aatcaggtga ttatgcctac tctgctgctg ttggtctgtt caatatgatt
     5581 attaatgtcg ttttattact gattgtcaac aatataacca agcggctaaa cgatggtcaa
     5641 ggcttgtaat gaaaggagaa aattatgaat agtgctttat caaaaatcga ccgtcaaatc
     5701 ttatggttga atcgagtgat tgtaactttt ttagtcgtca tcaccattgt tccgctgatt
     5761 tatgtactgg tagcttcttt tatggaccca gctactttga tcaataaagg tataagcttc
     5821 aatccgaaag attggacaat acagggatat caacgggtat ttgcagatga ttccatttta
     5881 cgcggttttg taaattcgtt gttttactct tttagcttca gcttattgac tgtatttatt
     5941 acgatgatca ctgcgtatcc tttgtctcga cctaacttgg cggggaaaaa gattattatg
     6001 actttttttg tcattacaat gttcgtgggt ggtggcttga tacctaccta tttattggta
     6061 aagaacttgg gcatgttaga tagtgtatgg gcgattatcg taccaggtgc tataaatgtg
     6121 tggaatatta tcttagcccg tacctatttt agtgctttgc caaaagaact ttctgaagct
     6181 gctactatcg atggcgccaa tgacttgcaa atactgttca aagtcatgct tccattagcg
     6241 aaaccaatta tgttcgtatt gtttttatat gcctttgttg ggcaatggaa ctcatacttt
     6301 gatgccatga tttacatcaa agatcccgac ttacagccgt tgcaactcgt attaagaaat
     6361 attttgatcc aaaaccaacc ttcacaagac atggtgggag ccaatactgc catggcagaa
     6421 atgaaacaaa ttgctgagtt gatcaaatac gcaacgatcg tcatttctag tctgccatta
     6481 atcataatgt atcctttctt ccaaaaatat tttgataaag gtgttttagt tggttctgtt
     6541 aaagggtaag tattgttcac tatttgtatg aataaaaatt ataaaggaga ttttaagatg
     6601 aaagcaaaat ggatgctgcc aatcgttttt acttccgtac taattttggg ggcttgtgga
     6661 ggctcaaaag aaaagagtaa atcaagccct gattatgaac tagaaaatgt ctcttttcca
     6721 ttgaaagaaa aagtatcttt aaaaatgatg tctcaaagtg cccctttggc tcccaatgat
     6781 cctaatgaca aattgatttt ccaacgatta gaagaagaga ccaatctcca tattgattgg
     6841 acaaactaca gtagtgattt tgccgaaaaa agaaatttgg atatcgctag tggtgattta
     6901 ccagatgcca tcttcaacgc cgctgcaggt gactatgatt tattaaactg ggcggaaagt
     6961 ggcgttattg taccgattga agatttgatc gaagattata tgccaaatct gaagaaaatt
     7021 tttgatgaaa accccgaata ccgacaaatg tctactgcac ctgatggtca catttactct
     7081 atgccttgga ttgaagaatt aggcgaagga aaagagtcga ttcatacagt aaatgggatg
     7141 gcttggatca acaaggagtg gttggataat ttgggtcttg aaatgccgca aaccactgat
     7201 cagttgatga ctgtgttgga ggctttcaag acgcaagatc caaatggtaa tggtgaagca
     7261 gatgaaattc cttttagctt tattaacaat ggaggaaacg aagacttaaa atttttaatg
     7321 ggggcattcg gtctaggtga taatgatgac cacttagtcg ttgataacga tggtcaggta
     7381 caatttactg ctaacaaaga agggtataaa gaagccatca aatatttcaa tgaaatgaat
     7441 aataaaggtc ttattgataa agaggctttc gaacaagatt ggaatacgta tgttgccaaa
     7501 gggaaagaac ataagtatgg cgtgtacttt acttgggata aagcaaatat cacgggtgca
     7561 gatgatagtt atgacgtctt gccagtctta gcgggaccag atggaacgaa acatgttact
     7621 cgtacgaatg gcatgggttt ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac
     7681 ttggaactta cagctaggtg gatagataaa atgtatgaac cgttacagtc tgtccaaaat
     7741 aactggggaa cctacggtga tgaagcacag gcgaatattt ttgaattaaa ggatggtatg
     7801 ttaaaacatt tgcctttaga ggggacagca ccgggggaac taagacaaaa aaccgaagct
     7861 ggaggaccat tagcagttct tgattcttat tacggcacag tcactactat gccagatgat
     7921 gcgaagtggc gtttagattt gatgcatgac acgtatttgc catatattac agaagacaat
     7981 atctatccac gtgtcttttt agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg
     8041 gatatgtggg attacatcta tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat
     8101 gaagaatggg aagaatacct tgctgaattg gaacgtgtag gtttggaaga atggattcaa
     8161 ataaaacaaa ctggctatga taattttttg aagggagcac aataagtgtt agtagaagaa
     8221 acggcgattt tggataaagc aaatcgattt attgaaatga tgcgaggaaa agttaaccct
     8281 cagtatcgac aaaactatca tttttccgca cccatcgggt ggataaatga ccccaatggg
     8341 tttatatatt acaaagggca ttaccatctc ttctatcaat actatcctta cgatagtcga
     8401 tgggggccca tgcattgggg gcatgcgcgc agtagtgatt tggtccattg ggaagatcta
     8461 ccagtagcgt tagccccaga tcaaccttat gacagcggcg ggtgtttctc aggaagtgca
     8521 attgaaagag acggaaaact atatttattt tatacaggct gtcaagaaat tgatggtatt
     8581 agccatcagc atcaatgttt ggcggtctct gaagatggta ttcattttag caaatacagt
     8641 ggtaatcctg tggtagcaga aaaacagcta ggtgaaaatg ggctaataca agaatttcgt
     8701 gatcctaaag taattgttca caacgatggt tactatatgg tagtagctac taaatctaca
     8761 cagtctactg gtagaatagt gatgtttcaa tcgtcagatt tgtatacttg gcacttttac
     8821 tctgtgctgc tagaagggac ttcagagcaa ggaataatgt gggaatgtcc tgatttattc
     8881 catttagacg gacgagatgt cttaatcatg tctccgatac aaatcaagaa gaacggactg
     8941 gaatatcata atatcagttc taccatggct tgtattggtg aggtaaactg ggaaacaggt
     9001 cagatgatag ttgataattt ccatgaaatg gattttggaa tggattttta tgcaccacaa
     9061 acaacaagag atcctaatgg tggacgggtg atgattgctt ggatgcagat gtgggatcgt
     9121 acattgccta cacatgagtt aggccatctt tgggcaggct ctatgagttt gccccgagag
     9181 ttaagagtga aaaaaaatcg attggtacaa aaacccatct caactgtata tagtcattta
     9241 gtttatcaac aaggcagtga aaatattgca gtgactgaca catcagtcgt atttcgaaac
     9301 gcgctgtctg attcttcata tttacatcta gtcgcagatt tggagaaagc tgaagttttt
     9361 acaattgaat tactgcggtc taagacggat tgtctcaaac tagcctatga cactgctaca
     9421 caggtttttg aattggatcg tcagaaacta ggaagagagc ttacaggggc ggaagaagac
     9481 cctctgaatg tacgaaaagt tgaagtacct ttgattgata atcagctcgt tcttgagatt
     9541 tttagagata cctcatcaat tgaagtcttt attaatgggt tagaagttat gacggctact
     9601 ttctatgagc tggaaaaagc tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt
     9661 caagcttttg aaacagcgag tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt
     9721 atttaatagg ttttgaagga taatgttttt agaaaagaac agatagctag atttcccatg
     9781 gatttgctat tagtattttg aaaaaattag taatttatga caaaattcat tatactaaac
     9841 ttgtgcagaa atgtgaggga tcaactatga aagcaacaat gaaagatgtc gcaaaattag
     9901 caggtgttgg agtaggaact gtttcccggg tattgaataa cggttctgtt aaagcttcta
     9961 ctagagaaaa agttgaagca gcaatgacag agttaaacta tcaaccagat ttttatgccc
    10021 gggggttaaa gatgaagcat acgaacacgg ttgctttgat tctacccacg gtatggcatc
    10081 cattttttgg cgaatttgcc taccatgtag aaacagcatt agaaagacaa aactacaagc
    10141 tttatttgtg taactccagt ggtaatagtg aaaaagaaca agaatatatc cagatggtca
    10201 gccaaaataa agtagacggc atcattggaa ttacttattc agatatcgat gaatacattt
    10261 cgagtaatct gccttttgtt agtattgacc gttatttcac tgaagaggtg atttatgtga
    10321 ccgctgacaa tgcggccggt ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc
    10381 agaatgtagc atatatcggt gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa
    10441 aatattttga aatcgagtgc cgtcaactgg ggatttccta taaagcgtta gatatgttag
    10501 aacctttaga ccatctctca gaacgtgtaa caaatttttt gttagagaat cccgatatcg
    10561 atgggatttt tacgatcaac gatccaatgg cattagctgt cattgatatg cttgaaaaaa
    10621 tagggaaaaa cgtaccagag gatgtccaag ttatcggatt tgatggtcaa aagatgacag
    10681 aaggagatcc ttatctagtc tcaacgattg cccaacctac aaagcaaatg gcggaagtgg
    10741 cagtggcaaa attaattgct gtcattaatg gagagacagt agaaaaacgt accgtattgc
    10801 cgattgaatt tggcgaaggt gacacaacga aacctttagt gagaaacgat tttgcttagt
    10861 gcaaatacgt ttcttttttt gaaaatgagt gaatgaaagg tgtagataaa atgttatatg
    10921 gtggaataga agccggtgga acaaagtttg tctgtgggat tggtaatgaa caattacaag
    10981 tgatagaacg gaaaagtttt cctaccacaa caccagaaga aacgatggag caagtgtttg
    11041 atttctttga taagtacaaa ggaaatatcg catcaattgg tgtaggagca tttgggccta
    11101 ttgatattca aatcgaatca agaacttacg gatatatcac caacacaccg aagttagctt
    11161 ggcaaaatta tcattttgta ggagctttgg aaaacgcctt gtcggttccc atctattgga
    11221 ctaccgatgt aaatgctgct tgttatggag aatatatggc agggtatgga aaaggtaaaa
    11281 atagtgttct gtattacacc gttggtacag gtgttggtgg tggtgctgta gtggatggga
    11341 aaatagtcgc aggttttagt catcctgaaa tgggacatat gctcttacaa cgtcataatg
    11401 aagatcaatt tgaaggaatc tgtccttttc atcatgattg tttggaaggg ttagcatcag
    11461 gacctgcgat tgaaaaacgc tttggaagaa aagcccagac tatctcattt gatcatcctt
    11521 attggacgat tgaggcagat tatcttgctc agtgtgtgta taacacaacg ttactatatg
    11581 caccggaagt aataatttta ggcgggggtg taatgaaaca gccgcaacta ctcgagttga
    11641 ttcgccaatc gtttaaagaa aaaatgggtt cctacgtgga tacgcctact ctcgaagaat
    11701 atctactaac tccaaggctt gctgacaatg cgggcttgat tggctgccta gctttagcaa
    11761 taaagaaact caatcattag aatagtattt attagaacta ttcataacat accggaagtt
    11821 taaaagggta ttctgaaact taaatagtct caattcattc ttctttcttg agaatctgag
    11881 tagagacttt tattctgttt caaattaata taattacgaa atgatattga gtacaagaaa
    11941 gttcttttta ccagatcttt taaatcgaaa aatctgatat atatatttat agtactaaaa
    12001 atctgattag ataaaaagct aattcaatag gaaaataaag gtagtgaata aaagcaaagc
    12061 ccttgttagt agttaatcta acaagggctt tggtagggaa aatggtagga aaccatctta
    12121 ttttttacga aaatcaggaa ctttagtaat tgaataatgt tgatttatag gtattcctca
    12181 tccatattat gttggctctt tattcccact ccactgttgc aggtggtttg ctggtaatat
    12241 catacacgat acggttaacg tgtgcgactt catttacgat acggacactg attttttgca
    12301 agacttccca agggatacgg gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac
    12361 ggatacctac agtgtagtca tacgtacggc catctcccat aaccccaaca gagcgaatgc
    12421 ctggtaggac ggtgaagtat tgccagatgt cgcgatctaa accggcattg gcgatttctt
    12481 cgcgcaagat agcgtctgat tcacggacga tttctaattt ttcttctgtc aattcaccaa
    12541 ggacacgaat acctaagcct ggtccaggga atggttggcg ccaaacgatg ctgtcaggca
    12601 tgcctaattg ggtacctaat tcacgtactt cgtctttgaa caatgtgttc aatggctcga
    12661 tcagcttgaa ttgcatgtct tcaggtaatc cacctacatt gtgatgtgat ttgatggttt
    12721 gggcagtttc agttcctgat tcgatcacat cggtataaag ggttccttgt gcaaggaaag
    12781 aaacgccttc ttcaccggca agtttggttg cttcatcatc gaagacatat acaaattcat
    12841 ttccaatgat tttacgtttt tcttctggat cagacacgcc agcaagtttt gataagaaac
    12901 gttctttggc atcgactttt ataatgttca agccaaattt tccgccaaga ctttccataa
    12961 cttgttctgc ttcaccttta cgcaacaata cgtgatcaac gaagatacat gttaattgat
    13021 cgccgatcgc tttttgtaaa agaacaccaa caacagagga atctactccg cctgaaaggc
    13081 ctaataaaac ttttttgtca ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga
    13141 agttatccat tgtccagtca ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca
    13201 agtcatttcc atattcggaa tggcgaactt ctgcatggaa ttggattccg tacattttgc
    13261 gttctgcatt ttggatcgat gcgatggggc aatctttgct ggtagcaacg acatcgaaat
    13321 cagtcggtgc ttgggtaact aggtcaccat gactcatcca aacggtttgt ttttcaggag
    13381 tgttttggaa aagggccgct tctgcagaag tgatttccaa ttctgctttt ccgtattcac
    13441 ggtttttggc tggtttaact tttccgccta atttataagt aatcaactgc ataccgtaac
    13501 agattcctaa aactgggatc cccaaatcaa aaatcttttc atcaatacca aaggccttct
    13561 catcataaac actgtttggt ccgccagaaa ggatgattcc tttagggttc attgccttta
    13621 cttcttctgc ggtaatgcgg tggctcatca actctgagaa aacaccgaac tcacgaatac
    13681 ggcgagtgat cagttggtta tactgactac cgtaatcaag tacgataatt tttggctctt
    13741 cgtcaaatcg tgttggtgaa gacaaatttg aataaaactt agtccgatat gcggcgcgtt
    13801 ctgtgcgccg catatttttt tagttttcaa agatcagacc ttgttgtaaa tagatccgtg
    13861 cccgaaagtt ataaaagttg cgataaccaa acgcaattcg tttaatcagc ttgatcttgt
    13921 tattcagccc ctcagtgacg ccgtttgagt gggacacctt aaaggcattt gaaatacccg
    13981 attggtagcg atggaagatc gtgaatttct ttttaaacga ctgaggtaac gtagatgaaa
    14041 ttgttttaag ggtttc
//
LOCUS       DADGHT010000075        14043 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.076, whole genome shotgun sequence.
ACCESSION   DADGHT010000075 DADGHT010000000
VERSION     DADGHT010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14043
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.076"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..627
                     /locus_tag="JX887_002035"
                     /pseudo
     CDS             1..627
                     /locus_tag="JX887_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177099.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            685..1599
                     /locus_tag="JX887_002036"
     CDS             685..1599
                     /locus_tag="JX887_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258012.1"
                     /translation="MIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLSFGIG
                     LTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQAPWRF
                     MIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEMNFQG
                     TYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEITFTF
                     KSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSYTFFS
                     KISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(1866..3035)
                     /locus_tag="JX887_002037"
     CDS             complement(1866..3035)
                     /locus_tag="JX887_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAX1258013.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            3239..4414
                     /gene="mltG"
                     /locus_tag="JX887_002038"
     CDS             3239..4414
                     /gene="mltG"
                     /locus_tag="JX887_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAX1258014.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            4550..5029
                     /gene="greA"
                     /locus_tag="JX887_002039"
     CDS             4550..5029
                     /gene="greA"
                     /locus_tag="JX887_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAX1258015.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            5198..5929
                     /locus_tag="JX887_002040"
     CDS             5198..5929
                     /locus_tag="JX887_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAX1258016.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            5926..6993
                     /locus_tag="JX887_002041"
     CDS             5926..6993
                     /locus_tag="JX887_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1258017.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            7000..7632
                     /locus_tag="JX887_002042"
     CDS             7000..7632
                     /locus_tag="JX887_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1258018.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            7772..8437
                     /locus_tag="JX887_002043"
     CDS             7772..8437
                     /locus_tag="JX887_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAX1258019.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            8465..8758
                     /locus_tag="JX887_002044"
     CDS             8465..8758
                     /locus_tag="JX887_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAX1258020.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(8826..9773)
                     /locus_tag="JX887_002045"
     CDS             complement(8826..9773)
                     /locus_tag="JX887_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAX1258021.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(9951..10754)
                     /locus_tag="JX887_002046"
     CDS             complement(9951..10754)
                     /locus_tag="JX887_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAX1258022.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            10900..11814
                     /locus_tag="JX887_002047"
     CDS             10900..11814
                     /locus_tag="JX887_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAX1258023.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            11862..12332
                     /locus_tag="JX887_002048"
     CDS             11862..12332
                     /locus_tag="JX887_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAX1258024.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            12417..13025
                     /locus_tag="JX887_002049"
     CDS             12417..13025
                     /locus_tag="JX887_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAX1258025.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            13159..13359
                     /locus_tag="JX887_002050"
     CDS             13159..13359
                     /locus_tag="JX887_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAX1258026.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         4737 a         2115 c         2712 g         4479 t
ORIGIN      
        1 gtaaaaatat ttatagttta tgcatttgtt agtttattat atttatttcc agcatttaaa
       61 aacatggaaa tatttggctt ttatgatacg gcatttcaca ttaatcgtgc gttaagttta
      121 gaatctattt ttagctcccc tattaatttt gaaacgttta gatcatatgg catgcaagta
      181 aataattttt acccatggtt aactctatat cctttatttt tattgatcaa gtttactaat
      241 ttagcaatag gctataacct ttttctttat attgttacgc tcattactct atttatatgt
      301 cattatgtaa tgtatgaaat taccaaaaaa catgttacta gctccttttt cgctattata
      361 tatacaacat cttcttttag gagtgtagaa atatttcttc gaggggcaat gggggaatta
      421 ctcgcaatgt caatacttcc tcttatttta ctcgggttta taaagcttta cgactcaaaa
      481 aaagaatctt gggttatgtt ggcgattagc atgactttat taatttacac tcatgttctt
      541 tctgtagcta tgactatggt aatgattata attgctttaa ttattcaatt ttatcggaaa
      601 aagaaaatag aaatcttctt aattattaaa ttaataaaag ctgctatagt tactttactt
      661 ctttcactag cgtttatagg tcctatgatt gagcagacat tgtatcaaga tctgaataga
      721 ccttatgtgg atatattaca aaaaagagca atttatctgg gtaaagagtt tttgattgga
      781 agtatagatt cagaattact atcatttggt attggcttaa ctttgcttat ttgtttaatt
      841 atactaacat ttaactttaa aaaattagga atcttatcta aaatcactta tataatgggt
      901 ataatatcta ttctactttg tacaaaaata tttccatggt ttgccttaca aaatactcct
      961 ttaaatatta ttcaagctcc ttggcgtttt atgatatttt caacattgtt catatctttt
     1021 tcagtatctc tatttatttc tccacagttg gaaaaatttt cttatacaag gagaagaaat
     1081 tttatactat tattaatatt agctatttca attttaaatt attcatcagt agttaacatg
     1141 gtgaaagaaa tgaattttca aggaacttat tctaatgaac aaatggaaaa taaacttgaa
     1201 gaatttgaga attttgatta tgtacctata ggctataaaa aagatcaatt gcttttgaaa
     1261 aaccatcaag ttacagaaga tggtcaagtt atttatagta gcttttctcc aaataaagat
     1321 gaaattacat ttacgtttaa atcttcaaaa ggcaaaacaa tagttttacc tgtattccgg
     1381 tataaaggat taacggttac tgttaattca aaaaatgcta cagtactaaa acaaggaggt
     1441 ccttttgtta cagtaaaaag tgaaagtgga ataaataaag taacaatcag gtattcatac
     1501 acattttttt ctaaaatctc attatttatt tctataatca cgctaattgt tcttcttttt
     1561 tattgcataa aattaaaaat aagaacaagc catgaatgat ttgctagcac atattttagc
     1621 aatctaaaga tactatttta gatttaatag gccctttgtc aaataatgtt ggtaaagaga
     1681 aatcttagaa taatttggac agaacagaaa gaagaacacc tctttctgtt ctgtttattt
     1741 ggaattaaag tctgtagcaa aaattgattt ttagatttgt cccacactct ttcctacgtt
     1801 tagtcgagta ctttttttaa gcaaatgcta ttcaaagaag tagtatttgc tatcttttca
     1861 tcatatcagc tatttgccaa cttagtagtt ccttccatca ggtcatagat ttggtttctt
     1921 agatcagcag taggcagttt gatagttttg tcagctttta tattgctttc catgatgata
     1981 gcatcctgtg aatctttgct aaatatagca gatgtatcaa aagagtcgat atttccttgc
     2041 gacaggatat aattatctcc gctatatacc ccaccactat atggatgtcc attcgcattt
     2101 tcacgccata atgagaagag taagtctttg gaaactagtt ttccagataa aacttgtgta
     2161 aacagcgtat ttaaatcata gacggacata ctgatattac cagtccctaa ttcgttatgg
     2221 atctctgttt cagattctgt cagtggttta aagtaatcat cctctttaga catttgatag
     2281 gatagtgcat gattggatga atttttgact tggtcataaa attttgtatg ctgtaatcct
     2341 aaaggttcga tgatatcatc ggtcaataat ttttcatacg gttgatttgt taatttgatc
     2401 aaaattccag tcaatatggt aaagttcaat gaatcataat gagaggtctg ataatctgta
     2461 aattttaagt gctgaatcgc aaattgaacg acttcttcat cagtcatcgg tatggttgga
     2521 gaagcagttc ggtgcaagcc tgagcgcata tacagcaagt cacggatagt aatttgctgg
     2581 ctgccagcaa tttgtggata gaattgagcc agcttagtat ctaaagaaag gtgcccacgc
     2641 tcgacttgtt ttaaaatcaa aagagtagtc aatgcttttt gaaccgaacc aatctgataa
     2701 taaagagaag gatcatttgg ttgttgcgtg agtttattcg catagccata gcctttttcc
     2761 atgatgatgc gattattttt ctttacgtaa attgagccaa tataatcatt ttttcttaat
     2821 agttgatcga ttttttcaac gagctgttgt tcattggtag tcagtatcaa ctttttttga
     2881 gctgattgag catgggcaac tatctgagag tgttcattat tgtaaaattg ccatccaaga
     2941 atagttcctg tagagaacgc actaaggcta aacaacacga caacgatcat taaaaatgaa
     3001 tattttcttt ttttagcatg ttttcctttt ttcataatag tttatttagt ctcctttctt
     3061 ttttacagaa agaataaagc taaaatagct tgtatcttga taacatttat tttaatctta
     3121 tagtaatgga tttactactt acatttttga tagaatattt aaataaaatc attcacgcca
     3181 attcaaatat catgtataat gaataaagtt acgaacttga tagtaaggag gagttgtttt
     3241 gtcaggaaac aaacaacacc caagtaaaga taaaaaagaa gccagtaagg cagctacagc
     3301 agatataatc gacaagcgga gaaatctgcg taaaaaagaa gataagattg tgaggaagat
     3361 cattttagtg attgctctta cattattgat tattggcgga tttcttggat ttaccgtgta
     3421 tcgttatgta gatagcgggt tgaagccttt agataaatca gatgaccaat tagtccaagt
     3481 cgagatcccg agtggctctt ctaacaagca gattggtgag attttggaga aggacaatat
     3541 tattaaaagc gggattgttt tcaattatta tacaaaattt aaaaatttaa ctggctttca
     3601 agctggctat tatcagttag cgcctaatat gactcttgac gagattggca aacagttgca
     3661 agaaggcggt acttctgagc caacaaaagt tgcagatggg aaaattgcca ttccagaagg
     3721 gtacgatatc gatcagattg ctgaacgggt agcgaaggta actggtaaag acaagaaaga
     3781 atttttagat ttagtgaatg atgagacttt ctttaacgag ttgcaccaaa aattcccaga
     3841 actgttggaa agtgcatcta aagctgagaa cacaaaatac cgtttggaag gttacttatt
     3901 cccagccaca tatgattatt acacgagtac ttcgcttaag gatctagtga ttgaaatggt
     3961 gaacaagacg aatacggtca tgcaaaacta ttattcagct atcaagcaga aaaatttgac
     4021 tgtacaagaa gttttaactc tagcttctct agttgaaaaa gaaggcgtaa aagaaaatga
     4081 tcgtaaaaac attgcacaag tcttctttaa ccgaatcaaa gcaaatatgc cacttcagtc
     4141 agatatctct gttttatacg cattaggtga acacaaagaa ttagtgacgt atgaagatac
     4201 agctgtagat tcaccatata atttgtatac caataccggc tatggacctg gaccttttga
     4261 caatccaagc gaagaggcaa tcaaggcagt attagaacca gcagaaaatg actattatta
     4321 tttcgtagca gatacgagca ctggaaatgt ttatttcgct aaaacttatg aagaacatat
     4381 ggaattagtg gaaaaatatg taaataattc ttagaaaaac aggctctaga cattgatcat
     4441 ttttagaaaa acatttacat ttgaagaaaa gcgtggtaat cttttttgga ctatattcct
     4501 caaaagatta ccttttgcgg tattttatcg aaaaaaggag acgttacaca tggtagagaa
     4561 agtttatcca atgactctag aaggtaaaga aaaattagaa aaagaattag aagaactaaa
     4621 aacagtcaaa cgcggagaaa tcattgaacg aatcaaaatt gcccgcggtt tcggagatct
     4681 ttccgaaaac tctgaatatg aatcagcgaa agatgaacaa gcatttgttg aaggaagaat
     4741 cacaacaatt gaaaatatga ttcgttttgc tcaaatcatc gataacgacg gtgtagatgc
     4801 agatgaggta tcaattggta aaacagttac attcatcgaa ctaccagatg gagaagaaga
     4861 agagtacacg attgtcggaa gcgctgaagc agatccgttt tctggcaaaa tttccaatga
     4921 ttctcctatt gcgcaagcat tgattggcaa acgtaaaaat gatgaagtaa ctattgctac
     4981 tccaggtggc gatatgttag ttaaaatcgt caaagtagaa caagcgtagt ctgactgaaa
     5041 gatctagaga gttcatctta ctgatgatac actctagatc tttttctctt tgtgtatttt
     5101 agatttcaac aaacgatctt acatctaaag tcctatagcc aacagttaaa aaaataggta
     5161 tgatgaaatg agaatgtgtc aggagggaga aagagcgatg aatagttctt ggcgtttttt
     5221 tgtggtagtt gaagcactac tgctgttatt tgctgtttgg caaatcgtaa acaatactgg
     5281 acttttgctt ttagtgatat tcggtatttt caatatatat ctagctatgc gcaaacatcc
     5341 tcgtactaaa tttcaaaatt ttcaattgat attaggaagt ttggtcattt tttttagctt
     5401 agtcaacagt cctgctttat ggatgatggc tgtatttgcc gttttattta ttggtctgaa
     5461 aggtgtagag atttcaggga tagatttaac caaaaatgct ttttggcgaa agaaacagat
     5521 catgatgatc caaacagagc aattaaaaac acataataat gagcggaaaa gacagcaatt
     5581 attcggtaac caacgtattg gaaacgacgt ctatgaatgg gacgatatca acatcgccgt
     5641 catttctggt gatactatca tagatttggg caatacgctt ttgccaaaag atgataatat
     5701 tgtgattgta agaaaaggga taggcagaac acggatctta gtacctttgg gcgtagccat
     5761 ccgattagag catgcgacat tagtaggaaa tgtcttgttt gaagaagagc aattttcttt
     5821 gaaaaatgaa caaatcaaaa tctacagcag tgattatgat gaaaaccctc gtagattgaa
     5881 gattattact aataccttga ttggagatgt cgaggtgata cgaatatgat gggaaaaata
     5941 tccagagcga tgctagctgt ttattcgggg attgcggctt tccttattat tctattttca
     6001 cttttcactt atttttatgc cagcaatcaa agtcattggt ggggagaatt actgcgtgca
     6061 cgtttattat atgttccgct tatcttccat ttgttagcca tttccttagg tgtaggatta
     6121 attgtctttc tattattatc acttattcaa aagacaaaat acgggaaaat cgaagaaaag
     6181 ctgcgtgcac tttcttctgg caattatgaa tccaaattgt tgcttcttcc gatcccaagt
     6241 gcatcggacg atttatacat caaagatatt gataaggaaa tcactaagat aaaagaaaaa
     6301 atgattgaag tatctagtga attacaaatt gtaacgagcc gtccccaata tgtagatgga
     6361 caaaccaaag aagaaatttt agaattagaa agacatcgat tagcccgtga gctgcatgat
     6421 tcagtttcgc aacaattgtt tgcagcaatg atgatgatgt cggcattgac ggagcaagca
     6481 gaaaaaagcg agacaccaga aatgtttcgc aagcagttga aaatggtagc agagatcatc
     6541 aacgcttccc agtctgagat gcgtgcgctg cttcttcatc tacgtccagt caatttagaa
     6601 gagaaaagtt taaagcaagg tatcgagcag ttattgaagg aattgcaaaa taaaatccag
     6661 atttcgctga aatgggatgt agaagatgta aaactatcta gttccattga ggatcacttg
     6721 ttccgaatcg ttcaagaatt gttatcaaat acattaagac atgctaaagc caatgaatta
     6781 gaggtatatt tgcacaaaat agacaataat cttttgttac gtattattga cgacggaaca
     6841 gggtttaata tgaatgaaac gaaaacggga agttatggat tgaacaatat caaagaacga
     6901 gtagctggta ttggtggaac agtaaaaatc attagtttta aaggtcaagg tacaagtgta
     6961 gaaatcaagg tccctttgat gaaggaggca tagataagga tgataaaagt tttattagta
     7021 gatgaccatg aaatggtgcg cttaggcgtc tctttttatt tatctattca agaagacatt
     7081 gaagtaattg gagaagctga aaatggacga caaggctatg agaaggcgat gacacttcga
     7141 ccggacgtca ttttaatgga cttagtcatg gaagaaatgg atggtatcga atcaacaaaa
     7201 gcaatcttaa aagattggcc agaagctaaa atcattatcg taaccagttt tattgatgac
     7261 gaaaaagttt atcctgccat tgaagcaggt gcagcagggt atttgttgaa gacctctacc
     7321 gcacatgaaa ttgctgatgc tataagggca acgcaacgtg gcgagcgagt attagaacca
     7381 gaagtgacaa caaaaatgat ggaaaaaatg agtcggcgaa atgagcctgt attacatgaa
     7441 gaactaacga atcgggaaaa tgaaatttta atgctgattt ctgaaggaaa aagtaatcag
     7501 gaaatagcgg acgaattgtt tattacactg aaaacagtaa aaacacatgt ttccaatata
     7561 ttggctaagc tagaagtgga agaccgtaca caagccgcta tctatgcatt caaacatggt
     7621 ttggtgaaat aaaaacgatg ataaagagga taatcaaaag ctgagaaaat aactattatt
     7681 tttcttggct tttttacaat aatgatgctt gcttttgttt ttgtaaaggc tttgttatac
     7741 tgagaaaaga agatactaaa ggaggaaaac ggtgaaacaa aattttgcaa ttgtaggtct
     7801 tggacgattt ggcggaagta tctgccgaac actgatcgaa gctggtcaag aagtactggc
     7861 tattgatagt aatgaagatc gggtcaatga atatatgaat atagccactc atgctgttgt
     7921 ggcaaatgca caggatgaaa tgacacttcg atcattaggc ataagaaatt tcgatcatgt
     7981 aattgtcgct attggagaag atattcaagc cagtatctta gttactctga tggtaaagga
     8041 aatgggcgta ccaaatattt tagcaaaagc ccaaaatgag tatcatgcca gagtacttga
     8101 aaagatcgga gctgatcgcg tcgtccatcc cgagcgagac atgggaataa ggattgcgca
     8161 taatttagtg tcaaagaata ttttagatta cctagagttg tcagataaat attctttagc
     8221 agaaatccga gtctccaatc ctaaattttt caacaaaaca ttagctgaat taaatttcag
     8281 gcaacgtttt gacttaacag tagtcgccat acgaagagta gatcaaacgg ttatcgcttc
     8341 tcctgcagca gatgaatatg ttcgtgaaaa tgataatcta ctggttattg gagagacagg
     8401 cgatgtggat attctagacg ataagatgaa tcaatagaaa gaaaagagaa agtaggttgt
     8461 tgggatgaaa ttaacggtaa cgccaaaagc acaaaagtgg tttgactcag aaattgatct
     8521 gccagaaact tacggaatac gtttttttgg aaaagtctac ggcaaaacag aggttcatga
     8581 tggtttttcg attggaatgt cagttgaaca gccagaacat cctgtaaaga aagtggaaat
     8641 tgatgggaca ctttttttta tcgaggaagc agatgaatgg ttctttaaag gatatgattt
     8701 acttgttgat tatgatccca acctggagga gccaacctat cactttaaaa aacaataaaa
     8761 aaagagaggg tgacacaatt tttgtcacct tctctttttt cttttgaaaa tattgttttc
     8821 agctattaat atcctgcaga caattttact tgattggttt gaagctcatg ggtggcaaag
     8881 tagcttttca gattggttaa aaaaatagcc attaatttct tttgaaaatc aggtgtcaaa
     8941 cctgcaatgt gggaagtaat cagtacattg tccattttcc aaagaggatg atcttgtgga
     9001 agaggctctt cctcaaaaac gtctaatgct gcaaaggaaa gttgctggtt atttaaagcc
     9061 tgcaccagat cttgtgtctt aacagaagca ccacggccaa cattgatgaa tacagatttt
     9121 ggatcaaagt gttcaaacat atgctgatca aagagcccag ttgtttcctc cgttagaggt
     9181 aagatattga ctacgaaatc tacttcagga agaacttcct ttagttgatt taaagaaaaa
     9241 gtcttttcca ttccttctgc tggatgaccg gatgtattga ttccatagca gttcatgtct
     9301 aatgctttgc atttttttgc aatcattttt ccaatatggc cagttccaat gattagtatt
     9361 tttttccctt ggatagattg gtaatggacc gatgaaccta accatttcat gtcactctgt
     9421 gccttttgtg cttgaaaaag accacgagaa tacccaagga tgattcctaa gacatgctcc
     9481 gtaatcgatt cactgtggat gccactacca tttgaaagta aaatatgttt ctttgaaaaa
     9541 gtctcaaggg gtagctgatc aacaccagct gagatagatt ggacccattt caaggtagaa
     9601 gaggctaata gtttttcttg gtagtctgag ttccagccca aactgatctc tacattttgt
     9661 agatcctctg gttgtaattc tgttttaaag atataaccag gcgctatagt atggatttct
     9721 tcgataaatt catcacgaaa tggacgatct gcataaatga ttctttctga catagttaat
     9781 ttcccgcctt tctttactct aagtgtagcg catacaagaa gaactttgaa gcgccttgct
     9841 tgttttttga gaaagaaata tttttcaaat aaaaaagggg ctgtgacaaa aaaatgtcac
     9901 aacctctaaa agggtctatt gaagtagaaa taacgagttg tctttatttc ttaattgatc
     9961 gatatttttg cccatccttt gacagcttga gcaaaaataa agattcctgc aaaagcaatg
    10021 aaggcgctag tgtcaaaaga aggaagaaag accatcaaga ttgttgcaat tatagtaggc
    10081 aatgaaattg aatagatcaa tgtttttaaa caatcaagaa aagtagcttt tgttagtcga
    10141 aagcgtgcat agagaaaagc agcaatgttg gtaaatagca aagtgatcag cagattcaga
    10201 aaactaggat aaatagaaaa tataaatgtc aggactttta tccaaagtgg tatagatgct
    10261 tcacttaaaa aagaacggag ctgcttacct gttaagtttt ttaaagattc attggtgtag
    10321 ggaagttcta attggttatt gttcaacaaa gcagaagtcg tgcctgtatt aggaagagct
    10381 atgataagtt tgttttttaa catcccgaca ctaacaaaat tccccatcaa atcagtagag
    10441 atgtcctgtt ctgttcgttt tccctctgga tcaaatgtga agataatgga gtttgtttgg
    10501 taaatgaatc cttctttttc ttcggtttga agctgcccgt tttggattgt aaaatcagga
    10561 atgcgagtag caatcttttg cccatccaat tgaatgttgt ttaagacttg aaaaacttga
    10621 aaagagattg gcaaagccat aattatactc aaaactaaaa gatagacaat ggctttccaa
    10681 aatgggacat ttctcgcctc ctttaggtct ttgaatcgta taaaggaact gataattaat
    10741 tgttttgttg tcataagtac tcctcatcta gtagtgtcat cacttgcaat tctagcgaag
    10801 tatcaagtga aatacaagtg ctttaaggaa acagctgaat gattggtgaa atatcaaaaa
    10861 aatgttattc ttgtctaaag actatccaat ataaataaaa tggaggaagg aatagtgcct
    10921 acacagccac agagatcatc aaaaaaacta tttggagtag tggttttgaa tgcggtgatc
    10981 actttatcag aatttattgg agggattatg tcagggagtt tgtctcttgt ttcagatgct
    11041 ttccataacc ttagtgatac attggcaatt attttttctt acggggcaca aaaaatggcc
    11101 cgaaaagaag caaataaaaa acgtacgtat ggctaccagc gtttagaaat attgagtgct
    11161 ttcatcaact cattcatatt gatcatatta tccttgtttt taaccgttga agcattcaag
    11221 cggttcactt caccagaaaa gataaatagt catttgatgc taacagtagc agttattgga
    11281 ttgctcgcga atttgttctc agtattatta ttacgacaag aagcagatga aagtttgaat
    11341 ataaaatcta gttatttgca tttgttaagt gatacactgt cttcggtaag tgtgattatc
    11401 ggagcaattt tgatccgttt tttcgatatc tactggatcg atccagttat tacactgatc
    11461 atttcgatat atatattgat agaagcgata atggtgatca aaaaagctgc cgctattttg
    11521 atacaaagtg cacctgctat cgactatgaa aaaatggaac aagaaattga agcaatcgat
    11581 ggggtaaagg atgttcatca tgtccatatt tggcagtata gcgaaaagat aattattttc
    11641 gacggacata ttgattttga agatcagcta ctaagcgaga ttgaaaagat atatcctcgt
    11701 ataatttctt tattaaaatt aaaatatggt attacacatg tgacgatcca agcagagaca
    11761 aaggcaaagg atcaaaaaaa attaattttt ttaaataaag atgaaagtta ttgaaatata
    11821 gagtatgata aataagaatt tttaataagg taggttggct catgaagcag tatcgacagt
    11881 taaaaggata tttagaagca aaaggatatt gggagatact agtctatctc ttttttggtg
    11941 gtttggctac gattgtaaat tttgttagtt ttgctctcgc acgccaatat tttgatttaa
    12001 gtatggcctt atccaattct atttcgtggt tttgttctgt attgtttgct tttgtaacga
    12061 acaaactttg ggtattccat tcaaaatcac cgaattttac acatgcactt attgaatgcg
    12121 gtaagttctt cttctaccgt atcctttctt acggattgga catgggggca atggtattgt
    12181 tgatcaatgt tatgaacagc aatgagtatg tggcgaaaat catcactcaa attattgtta
    12241 tccttgcgaa ctatattttc agcaagttgt ttatttttaa agaaactgag gtttttgaag
    12301 aagaagtagg tcaaagtgaa aaagacgact aggcataaca attgaagaat ttccttctct
    12361 ttgttactct ttgtaatgta gacattatta agaaaacatt gaggaggaat ttttttatga
    12421 cttacacatt accagatcta ccttatgcat atgacgcatt ggaaccttat attgacgaag
    12481 aaacgatgca tctgcatcat gataagcatc acaatactta tgtgacgaat ttaaattcag
    12541 caattgagaa atacccagaa ttaggcgaaa aaacaataga agaattatta tctgatatgg
    12601 acgctattcc aacagatatc aagacagctg tacgtaacaa tggtggcgga catgctaacc
    12661 attcattttt ctgggaaatc atggcaccaa atgctggtgg cgaacctaca ggagaaataa
    12721 aagaagcgat taatgaagct tttggtgatt tttcttcttt taaagaagaa ttcaaaaaag
    12781 cagccgctgg acgatttggt tctggatggg cttggcttgt aatggaaaat ggaaaattag
    12841 ctattacctc tactgcaaat caagattctc cattgatgga aggaaagaca ccaattctag
    12901 gtttggacgt ttgggaacat gcttattatt tgaaatataa aaatgtccga ccagattata
    12961 ttgcagcatt ctggaatgtt attaattggg atgaagtaaa caaacgtttc gaagcagcaa
    13021 aataaccatt tcctccgtca tatcagtctt aaaaataatt tggaaaataa aagagcgaaa
    13081 gcttgctagc gttttctaaa ttgggtataa tgttcttgca aggttacttg caagaacttt
    13141 tttggaggat atacatttat ggaacacgga acggttaaat ggttcaacaa tgaaaaagga
    13201 tttgggttta ttacagtaga cggcggagat gacgtatttg ttcatttctc agcaattcaa
    13261 ggagacggct tcaagagcct agaagaaggt caagaagtag aattcacgat tgttgaaggt
    13321 gcacgcggac ctcaagctgc tgaagtgact aaattataat aatttgttga ataaagacac
    13381 gacttcttag agagtcgtgt ctttttgtct atttatgaag tttttagatt ttttggctaa
    13441 gtaaatgcat ttgttcactt gacatgtcct aactaattat caagcaagga acattttctt
    13501 cgttagtaat ggattttaaa gaaatttcag tttttggatg ttgaataaaa gaccatttgt
    13561 gaaaccacta gtatacatac tcattaccat gtcaattcta ttactttaaa agaaaatcgt
    13621 tttactttga agaggagcat atctatccat taaaagatga tggtaatgca atcactagtt
    13681 cgagtcattt taagagccat gcagtgagct ggaaataaaa cgaatagaag atgggtttaa
    13741 caaaaggacc agtcatagga agaaattgtc gtgaaatcga atgataatct gaacggtagg
    13801 caaagactgt taaaaagatg ggaaaggtat gtgcgatcat tttactgcac gattatttgg
    13861 aaaatacctt gttgttcgct ttttctggaa aaaatacata aaaaaagata aaacgattgc
    13921 gaactgcgtg tattcggtct ttcgatcttt ttcacggtat ggtatgatag ttaagaattt
    13981 tgagaaattt taaaaaataa taatcgttac acaaaaatgt tttttaaagt tttcttatga
    14041 tta
//
LOCUS       DADGHT010000076        13944 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.077, whole genome shotgun sequence.
ACCESSION   DADGHT010000076 DADGHT010000000
VERSION     DADGHT010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.077"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..120
                     /locus_tag="JX887_002051"
     CDS             <1..120
                     /locus_tag="JX887_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAX1258027.1"
                     /translation="QGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
     gene            complement(298..2295)
                     /gene="tkt"
                     /locus_tag="JX887_002052"
     CDS             complement(298..2295)
                     /gene="tkt"
                     /locus_tag="JX887_002052"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAX1258028.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2397..2648)
                     /locus_tag="JX887_002053"
     CDS             complement(2397..2648)
                     /locus_tag="JX887_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAX1258029.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2795..3418
                     /gene="lexA"
                     /locus_tag="JX887_002054"
     CDS             2795..3418
                     /gene="lexA"
                     /locus_tag="JX887_002054"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAX1258030.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3598..3816
                     /locus_tag="JX887_002055"
     CDS             3598..3816
                     /locus_tag="JX887_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258031.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4105..4617)
                     /locus_tag="JX887_002056"
     CDS             complement(4105..4617)
                     /locus_tag="JX887_002056"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAX1258032.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4631..6928)
                     /gene="recJ"
                     /locus_tag="JX887_002057"
     CDS             complement(4631..6928)
                     /gene="recJ"
                     /locus_tag="JX887_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAX1258033.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7070..7504)
                     /locus_tag="JX887_002058"
     CDS             complement(7070..7504)
                     /locus_tag="JX887_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAX1258034.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7514..8302)
                     /locus_tag="JX887_002059"
     CDS             complement(7514..8302)
                     /locus_tag="JX887_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1258035.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8299..9240)
                     /locus_tag="JX887_002060"
     CDS             complement(8299..9240)
                     /locus_tag="JX887_002060"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAX1258036.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9417..10004)
                     /locus_tag="JX887_002061"
     CDS             complement(9417..10004)
                     /locus_tag="JX887_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAX1258037.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10225..11538)
                     /gene="obgE"
                     /locus_tag="JX887_002062"
     CDS             complement(10225..11538)
                     /gene="obgE"
                     /locus_tag="JX887_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAX1258038.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11826..12836
                     /gene="gap"
                     /locus_tag="JX887_002063"
     CDS             11826..12836
                     /gene="gap"
                     /locus_tag="JX887_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAX1258039.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12921..13856)
                     /locus_tag="JX887_002064"
     CDS             complement(12921..13856)
                     /locus_tag="JX887_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1258040.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3857 a         3122 c         2453 g         4512 t
ORIGIN      
        1 caaggattca tctcatccgt tgcgtccaaa agaaaccata tccctagaaa atcactaaat
       61 taccaaacac cattagaagt ttttttgagt tacgtaaatg gaaagttttg tctcgcttaa
      121 tttgacaaat aatattctca agaaacacaa actaatccga agaattcttt gttttgtcat
      181 ttaaatgtaa catagccgaa aacgaaaagt aatattgatt tattcttcta acacataaag
      241 aacagctgtc tccaacttgc agacagctgt tcttatcagt caaacaattg cttggatcta
      301 tgatagttga ttgtacgtat tcacgacatt ttctactgta aatccaaatt cttctaaaat
      361 tttagtgcca ggggcagatg caccgaaatg atcgattgta atcgttgcgc cctctgttcc
      421 tacgtagcgt tcccatccaa atgatgcagc agcttcgata gccacacgtt tcttcactga
      481 tttaggaagt acactttctt tatattcaga agattgtttt tcaaagaggt caaagcttgg
      541 catagaaaca acagaaacat ctttgccttt ttcagccaat tctttttgag ctttcacagc
      601 caaatcaact tcagaacctg ttgcaatcaa aataccttct ggtgtttctc cttgtgatgg
      661 agaaagaaca tacgcgcctt ttttcaccat ttcatctgct acttcttttg tagaaggcaa
      721 tactggaagg ttttgacgac tcaatacaag gatagtaggc gcatctgttg tctccatcgc
      781 tactttccaa gcagcacgtg tttcatttcc gtctgccgga cgaatcactt gaacaccagg
      841 catgcagcga acagatgcta gttgttcaat cggttcgtgc gttggtccgt cttctccgac
      901 agcaaccgag tcatgtgtta agacgtaaac aacaggagta tgttggattg ctgctaaacg
      961 aactgctggt cttagataat cgacaaagac aaagaatgtt ccaccgtaga tacgagttcc
     1021 gccatgaagt tggataccat tcatagccga agccattgca aattcgcgga caccgaacca
     1081 gatgttgcgt ccttcataat gttcaggagt gaaatcttta tctgcagcca ccattgtatt
     1141 attggaacct gacaagtccg ctgaaccacc ccagaagctt ggtatagctt tcgataattc
     1201 ttggatgact tctttacttg aaacacggct tgcttgactg cttccaactt cataagttgg
     1261 caattctgca tcccagtttt ctggtagttt gccatcaaaa gcatcttcaa attgttgtgc
     1321 taattcagga taagcttttt tataattggc aaacatttca ttccatgcat cttcagcttt
     1381 ttgtccttct tctatcatcg tttgatggaa gcgggcagct acttcttctg gaacagtgaa
     1441 atctggatac tcccaaccat aaacttcttt agccatcttg atgccatctt caccaagagg
     1501 agcaccatga acagcagatg ttccttcttt aggagcacca tagccgatga ctgtttttac
     1561 ttcgatcaat gttggtttgt ctgtttcagc ttttgcttct tcaatcgctt tagagattgc
     1621 ttctaggtca tttccgtctt tcactaagat atgttgccag ccatatgctt catagcgagc
     1681 accaacgttt tctgtgaaag cttttgaagt tggaccgtct agtgaaatat cgtttgaatc
     1741 gtataaaacg atcaatttcc ctagtttcat atgacctgcc atcgaacttg cttcttgaga
     1801 taccccttcc atcaagtctc cgtcaccgca tattgcatac gtatagtgat ccatcacatt
     1861 aaagttttct ttgttatacg ttgctgcaag gtgcgcttct gccattgcca taccgacagc
     1921 cattgcaatc ccttgtccta atggccctgt agtggcttct acaccatctg tatgatgtac
     1981 ttcaggatgt cctggtgttt tagaatccca ttgacggaat tgtttcaaat catcgattgt
     2041 cacttgatag ccagctaaat gaagcaagct atacaacatt gctgacccat gtcctgccga
     2101 aagaacgaaa cggtcgcggt cagcccagtt ttttgatgtc gttggattta ctttcaggtg
     2161 ttttgtccat aacgcatatg ccataggtgc tgcgcccatc ggcaatccag gatgtcctga
     2221 gtttgctttt tggactgctt caatacttaa tgtacgaatt gtgttaacgc caagttggtc
     2281 aattttgtca aacaaaataa cccctcctat taatttaggt tttttttacc tttatttctt
     2341 acactttcat tctataagat gtcacacgaa aaagcaatct ttttcagtat tttttactaa
     2401 aagttgtcat ttcggttgtg taagcctttt ttcttttgga tttcttttaa tttttccggg
     2461 gtcacgtcat tgccctcagg atcgacgact ttcattcctt cgatatgatg acgcataccg
     2521 gaacgaaaag cttccaaata ctctttgcgc aagttgattt gttcttgttc ttcggctttt
     2581 gagagaccat tttccttctt tttacgtgca agttcattga tccgctctat tttttcaggt
     2641 gacagcatgc tcagccctcc ttttactctc cttcatatta tataaaaact gaaaaaaaaa
     2701 caactagata aactaaataa aatacgaaca ttcgtttgat ttagcgcttt ttatatggta
     2761 ctatttattt atcaagtgaa agaaggtgta ccttgtggcc cgacaaactg aatcaagaca
     2821 aatcgaagtc ttacgatata tccatgaaca agtaacccaa aaaggatacc cgccgactgt
     2881 ccgtgaaatc ggggaagctg ttcagctttc ttctacttct actgttcacg gtcatcttgc
     2941 acggcttgaa aaaaaagggt ttatccaaag agatccgacg aaacctcgtg caatcgagtt
     3001 gacaaaacaa ggtttagaaa agattgggat tcgtccaaca actattccag tacttggcgt
     3061 cgtaacagct ggagaaccca ttttagcagt agaggatgct tcagacttct ttccaatccc
     3121 tcctaatctt tcttccgaag aaggcagtct ctttatgctg acaattcgtg gagatagtat
     3181 gatcaatgct gggatattgg atggtgacaa cgtgatcgtt cggaagcaag aaactgctca
     3241 aaatggcgat attgtcattg caatgactgc cgaggacgaa gcgacttgca aacgattcta
     3301 taaagaaaaa aactttttcc gtctgcagcc tgaaaacgac ttgctcgaac caatcatctt
     3361 agatcaagta tctatattag gacgagtagt aggactttat cgtagtcata tctattaatt
     3421 gctactaatt aaaagaaaac tttttaaaaa gagtttgaga cgttggtctc aaactctttt
     3481 ttcgcccggg ttcttcttct ttcaaatttt tatcacttcc ctctttacaa accgaacaaa
     3541 tattcgtata ctaaatatac gaacaattgt tcgcataaat taaagaggtg agaattcatg
     3601 aaatcaatga gacgtcttgg cttagtatta actgttttgt ttttaggtat tattattggt
     3661 aatttcggca tacgtccagc tttacttgtg tttgttccgt tatttacttt gtggttcatg
     3721 ttgtgggatg aaaagaagta ccgtcaatct gagcggcgca gaattcatga agatcatttc
     3781 tatcatgagc cctactacag atccaggcaa tcataataag gattgactgc taattattca
     3841 aaagacaaga agttaaactt ttacgggggt gtgacaaaaa tcggtcacat cctttttttc
     3901 gaataaacgg tgttctaaag ccagtttttc ggtattaagt caaattgcgg aaaaagtgat
     3961 tttttaaact tctactggtc tttgcttgtt tccatttata aaaaaatagc gaccctcaaa
     4021 agtcagatag agaatctgac ttttgagggt cgctttaaaa tcgcttcttt aagaataaca
     4081 tcaagaatag cttctttttt ctgcttaata ttccattaat gtaatgatgt catatccttt
     4141 gattttgtcg cgtccatgga gatccatcaa ttcgatcaaa aatgcgcagc ctacgactac
     4201 accgcctaat tgttcgatca gttcgatcgt cgctttgatt gttcctccag tagctagcaa
     4261 atcgtcacaa atcagcacac gttgacctgg tttaatggca tccttatgca atgtcaatgt
     4321 atctgttcca tattctaatc cataagtcac ttcgatggtt tctcgaggta acttcccttt
     4381 tttgcggact ggggcaaaac cgactcctaa ctcataagca acaggacatc ctacgatgaa
     4441 tccacgggct tctggcccaa ctaccatatc aattcgtttt tcttttgcat aatttacgat
     4501 ttgtttagta gcttcccgat aagcgtcacc atctgccatc agtggggaaa tatctcgaaa
     4561 cacaattcct tttgacggat agtcgggaat actggcaata taatctttta aatccactct
     4621 ttgtttcctc ctaggttgtt aaccatttct ttatggtagg aatatcgctc aaaagcaaaa
     4681 attcctcaac tttgatttta ttgagccgtc gctggtataa tctgctctca gtcaaaggat
     4741 gactttctgg gctagcgact ttttgtaaaa caccgttctc tattgtaaca aatttcaatt
     4801 caaaaaacac ctgtatcata aaaattaata atttttcagg gatacgcaaa tattgagcta
     4861 ttgcttttat tttatgacgt atatcaattc gttcttgaga atggatcaat ttaaacaatt
     4921 ttgcgtactg ttctcttgtg cctaccccat tcaaataggc ctcatcaggt gaaatcccca
     4981 tcagataaac acgattgaat gaataagacc gaaaaacttc tttcagatcc gctaaatcat
     5041 ctggacaatc cataacaact agagagtttg gttttctttt ttcaattatt gcctttacag
     5101 aatctagtcc ttcgaaaaca atcgcagctt cctggataat ctcaggcacg aatttcaacg
     5161 tcgaagaatc aaatgctaaa taaaggctac cttccgacgt tcggctctgt tcacggaaac
     5221 gttttgcccg ccaatcaaat acttgcagac cacccacaga aaaatcagat accatcagct
     5281 gcggtttctt acgcccgttc cattcattga tcgaaagctt tcctaccaca tctacctgat
     5341 tattcagcag ttcttcttct tgagtaccaa aaccaaaagc gaccgcatca agctgactcg
     5401 atgcatcgga aaggacaaat ttcagatgct gttggtttgc tccgattctt ttgatatttt
     5461 ctgcttggac ttgtcgaaat aaaaactgag gcaaaggatt atccgtacca aatggcgcca
     5521 atagtttcag ctcatcaatt cgctctactg ttacttcatt tggcagcaat acttcatcaa
     5581 ttctcaactc aggccctctc atcaagtcaa tttgatgatc gactatatat tggttcatct
     5641 tctcctgtag tatagtgaca ttttcacttg gcatcgttaa accgactgct gcatgatgtc
     5701 ctccgaagta agtaaataaa tctcgcatct ggtcaagcat ttcaaaaaga ttcaaggctt
     5761 caatactacg tccagatcct ttagctgatc catcttcttt taaagtaagg acaagcgttg
     5821 gtttacccgt ttcattcatt attttcccag caacaatgcc caaaacgcct tcatgccatc
     5881 ctcggtttac caatagatgg atatgattct ccttattgac catcgctaat gcttcttgtg
     5941 ttatctgctc tacgattgct tttctttctt cattgatctc attcaatttt tttgcttgaa
     6001 cggatgcttc ctcttcatca aacgtcgcaa gtaacgagac ggcaggacgt ggatcgccca
     6061 tccgaccgat tgcatttagt ctgggagcaa tcgaaaaacc gatcgttgtt tcgtctgcgt
     6121 ccctcatttt tacgccgctt tcttcaaata gcgcctgaag tcctatccgt tctgaatgat
     6181 gaatggcatc gattcctaat gaaacaagga ttcgattctc atcagtcaat gaaactaaat
     6241 cggcgatcgt tcctatcgct actaaatcca aaaattctgc aggcggttct tccaataatg
     6301 cagaagctac tttgaatgct actccgactc ctgccaaatc tggaaatgga tagtgccccg
     6361 ctggatgacg agggtgaaca atcgcataag cgtctggtaa attctcaggt agttcgtgat
     6421 gatctgtaat gatcacgtct acaccagctt gctgagcgta tgctaccgca tcatttcctg
     6481 ctaccccgtt atcaacagtg atgatcaact ggattccttc ttcgatcttt tcttggtata
     6541 ccgattggtt tggtccatac ccatgctcaa atcgatttgg caggaatact tctacttctg
     6601 caccaagtaa ttccagtgtt tctttcatta ccgttgcact ggtgatccca tctgcgtcat
     6661 aatcaccgta aacgaggatt ttttctccac tgattacagc ttcttggatt cggctgattg
     6721 ctttatccat atcgtgtatc agatacggat catgtaattc ttgttccttt ggatgtaaaa
     6781 atcggttgat atccttttcc tcatggtaac ctctttgcca cagtaactta ccgacaaatg
     6841 gagataattt cagttcacgg atcatttgga gaaaggattc agaaggctct gtctcgctta
     6901 acttccaatc aaaatttgct tgtctcactt tctcactcct aacttagtta ttatagcaaa
     6961 ggaaatcagc aaaaaaaagc agaaagaaag aataaaaaca gatcagatcc gctagacaga
     7021 tgttcagcag gacctgatct tttgtacgac catttatgaa atatccctat tagtcaaaat
     7081 aattgaagct ttgtttgggc gattgagttt tttgttcttc cggcgctttc aattgactga
     7141 tttgtgcggt tttcgcttgt aactccgcct gataagcagc ttccaactcc gcacgttcgt
     7201 ttctaaactc gcgttgctgt tcttcttttg cttcttcaat tttcttttga agttctgttt
     7261 gatattctga catttcctga gtcagctgtt tgatttgctt tttttgctgc catagtgttg
     7321 ccgaagcagt caaaaataca atcagtgcac caatcagcgc agaaccgatg atcactaaga
     7381 tcaatggcgc agaaaaggaa gtgaagccaa aacttacagg aacattttta ttgttcaata
     7441 cagcaaaaag aacaataatc aaaactaaaa caaatccaag aatcacattg ctttgctttt
     7501 tcaattcctt cacctacttt ttgttaaaaa ttccgctggc taaataatca ccaatcgttg
     7561 gaaacagcgt ataaaatttt gatgcaactt ctaaaataaa cggttgattg atttcccgtt
     7621 ttggatgtct catattgcgg acgatcattt ttgccaactt ggcaggttct aaaacgattt
     7681 gtccgacttt ttccaaatag cttccgcttg gatcagcctt atcgaagaaa tttgtctcga
     7741 ttggacctgg attcactgtc gtaacagcta cgccaagtgg tttcaattct aatcgcaaag
     7801 cgttggagaa gccaaggact gcaaatttcg tggcagaata aaccgttgat tttgcagttg
     7861 ccatttttcc agccatagag gcgatattaa tgatatgacc ttgtcttctt tctgccatat
     7921 cgatcgcaaa tttttgtgtc aaaaccatca ttcctaagat gttgacttca aacatatcgt
     7981 atgcttttcc aaggtcgaat gtaaggaagt cttcgaaaat cccaaaaccc gcattgttta
     8041 ccagaatatc gacgcgcccg acttcttcca tcaccttttc atataattcg tccacgcttt
     8101 caggattgct gacgtctacc ttgaaagcat aagcctcttt gccgctcaag cgtctgcact
     8161 cgtctctgac accttctaca aatgccattc ttcgtgcgca acttataacg attgctcctt
     8221 gctttgctgc ttcataacag atttgtgcgc ccagaccgcc tgaactacct gttactaaaa
     8281 caactttatc ttctaaattc atgcctcttc ctcctcgcga aatggaatct caatgctatc
     8341 aaaatctttc ataatcgtcg tgttttcaaa cacttcttgt gcttcttttt caagctctaa
     8401 agctgctttt cctaaatatc tcgcactgat atgagtaagt agcagccgtt ttgcctgcgc
     8461 ttcttttgca acttcagcag cttgatgagt cgtggaatgg aaatagttgt gcgccattct
     8521 tgcttcatct ttattaaatg tgctttcatg taccagaata tcgctatttt ccgcaagcac
     8581 aacggaatta tgtgtttttc tcgtatcgcc taaaatagtc acgattcgtc cttttttatc
     8641 tggacctacg aaatcttttc cattgatcgt ccgcccatct tctagttgga tcgtttcacc
     8701 ttgcttcagt ttgccgtaca gtggtccagc tggaatacct aattctttta gacgatccac
     8761 ctgcaattct cctttatgat catgttcaac cacacgataa ccaaaactgt cgatcccatg
     8821 atttagtttt tttgtataaa cagaaaattg ctgatcagta aaaatcgggg ctgtttcatt
     8881 tagctcaatg aatttcagcg gataacttaa acgcgtttgc gaaataccta aagagacttt
     8941 tatgtattcc tctatccctt ttggcccgta aatctctaat ggcgtatccc caccttgaaa
     9001 tgaccggctg ctgatgagcc cgggaagtcc aaaaatatga tcgccgtgta aatgtgtaat
     9061 gaaaatttta ccgatttttc tcggacgaat agtcgttcgc aaaatctgca tttgcgtgcc
     9121 ttcgccacag tcgaacaacc aaacttcatt gcgctcgtct aaaagtttca atgctatact
     9181 tgtcacattt ctatgttttg caggaacacc tgcacctgtt cctaaaaatt gtaattccat
     9241 aatctacctg actttcttta agttcctctt taattttagg gtaaaaagaa gggataatca
     9301 accgtaagtc gagaatgggt tcaaattaaa aataacgttc taaagcgata gcgttttctt
     9361 tgaaaattac tataaaaaca gcagcgaacc cgtttgagat cctctgctgt tttttattaa
     9421 tttgaagatc cagaactttc attgtcgttg gaagtttgcg gatgtttgtc cttccaagtc
     9481 ttttgtgcag cttctttcgc atgattttca gcttctttcg catcatgcac atctttttcg
     9541 acatcttcat aatccaagcg agtaatttct ccgcctaatt ccatcattac caattgattc
     9601 agtgggcgat tgtcctcttc atcagcaatc aagatcagtc ctgtagctcc ttcaccgatt
     9661 ttatttccta caaagtcgaa cacggtctgg gcatctttta tttctttggc atcttgtgtc
     9721 gcaccgatca ttcctccggc aaaccatcct aataaaatcc ctagcggacc acctaataca
     9781 ccaaccaaca ttccgattaa tccacccgta gaagatttgt tattaccggt aaagtcgata
     9841 aaatcttcta ttttgaattg atgtgtccca ttaggatcat ggctgacaac tgccatctgt
     9901 tctcctttaa tcgaacgaac agcatgtaac tttttgattt ctgaaaatgc ctgatatgcc
     9961 tggctttcta cttgaaaatt taaaatgatt actcgtttgc tcattaaaaa cgcccctttc
    10021 ataccttctt gttatttatt ttacctttaa ttgaaaaata agaaaagaaa agcactcttt
    10081 ttttccaata aaatagggct gtgacaaaag tcgtatcaca gctccttttt ccgaataaac
    10141 ggcgttcttg aagctgatca cttctgtcac aacctccctt aaatctgaat ctatattttt
    10201 tggtatttgt ttttatttgc ttgcctattc gacaaattca aattcaaact caccgatacg
    10261 tacaaggtcg ccatctttcg caccgcgtgc ccgaagagct tcatccacac ccataccacg
    10321 taattgacga gcaaaacgca tcactgtttc atcatgatcg aaattcgtca tttggaataa
    10381 tttttcgatc ttctcaccag ataagatcca cgttgcatct gaatcacgat cgatttggaa
    10441 ctcaggacct tctggattga atccatagtg tacagtttct tcttccagtt cttcttcgta
    10501 caatgggaat tctggcgtta cttctaacaa atctgctgta gcattcaata acgcgtccaa
    10561 tccttgtcga gtcactccag aaattggaaa tactgggatg tcatcagcaa attcatcttc
    10621 tttttccttg ttcagctgtt ctttgaattt cactagattt tccggtgcat ccggcatatc
    10681 cattttgttt gccacgatga tttgcggacg ctctagcaag cgtaagttat aagtagataa
    10741 ttctttgttg atggcaagat agtcttcata aggatctcgt ccttccatcc cactcatatc
    10801 gatcacatgt aaaattactc gtgttctttc gatatgacga aggaattgtg tacccagccc
    10861 aacaccttgc gaagctcctt caatcaagcc tggcaagtct gctgcggcaa aacttctgcc
    10921 atcacttgta gtaaccattc ctagattagg tacgagcgtc gtgaaatgat aagcgccgat
    10981 ttttggacga gcagatgaaa taacggatag taaagtcgat ttcccgacag atggaaaacc
    11041 tacaagtcca acgtctgcca atactttcaa ttctagttcg atttttcgct cttgtcctgg
    11101 ttcaccgttt tcagcaattt ccggtgcagg attccgagga gaggcaaaac ggatattccc
    11161 tcgtccaccg cgtccacctt ttgccacaac tagtgtttga ccattttcaa ttaaatctcc
    11221 taaaagagca ccagtctccg catctcggac agtggttcct tgtggtactt taacataggt
    11281 atcttctgaa ccacgaccgt gcatcccttt actcatccca ttttcacctg gctgcgcttt
    11341 gaaatggcga ttgaaccgaa aatccatcaa tgtacgtaac ccttcatcga cgatcaagat
    11401 gacatcgccg ccacgaccac cgtctccgcc agccggtccg ccgtcaggaa cgtatttttc
    11461 gcgacgaaat gcaaccattc cgtctccgcc cttgccagct ttcacatcga tcgttacttg
    11521 atctaaaaac atggacataa ttaagtcctc ctattattca tttatttatt tgactgcctg
    11581 aatttccaca ataaacaaaa gtcttactta ttttatcggt gaaatctgat tttgtctatc
    11641 atttcagcaa aaagattgtt taccttcttc tttttttatc atttggtaag gtttccaacc
    11701 ttttttctgc taccaagtat aattttttga caaaatattc tttgcgtagc agaataacag
    11761 tgtattaatt gtattaattg aggatgccgt ttcacagcac ccctaataaa ggaggaactt
    11821 ttgatatgac agtaaaagta ggtattaacg gatttgggcg tattggccgt ctggctttcc
    11881 gccgcatcaa agaagtctca gatgatattg aagtagtagc aatcaacgac ttaacaagtc
    11941 caactatgtt agcacaatta ttgcaatttg actctactca tggtacttat cctggcacag
    12001 ttactgcaac agaagactca atcgtagtgg atggcgaagc aactcgtgtt tatgcagaac
    12061 ccgacgcaag caaaatccct tgggcaaaag aaaacggtgt agatatcgta ctagaatgta
    12121 ctggttttta tacatctgaa gaaaaagcaa aagcgcattt agatgctggt gtcaaacgag
    12181 tagttatttc tgccccagct ggtgctatga aaaccatcgt ctataacgtc aatgatgata
    12241 cattagatga aaacgacaaa atcatctcag caggttcatg tacaacaaac tgtttagcac
    12301 ctatggctta tttcttaaat aatgaatttg ggatcgaagt tggtacaatg acaacagttc
    12361 atgcctacac ttccacacaa atgctcttag atggacctgt aaaaggcggt aatttgcgtg
    12421 ctgctcgttc agctgctgac aatactatcc cacattctac tggtgctgcg aaagcaatcg
    12481 gcttagttat ccctgagcta caaggaaaat tacaaggaca cgcacaacgt gttccagtcg
    12541 ttgatggttc attaactgaa ttggtttcag tattgaaaac aaaagtaact gctgatcaag
    12601 taaacgaagc aatcaaaaaa cacacagttg acaatccttc attcgggtat gatgaccgtc
    12661 aaatcgtttc tagcgatgtc attggaacaa ctcaaggttc gatctttgac ccaacgcaaa
    12721 cagaagtaac aactgctggt gatttccaac ttgttaaaac tgttgcatgg tatgacaatg
    12781 agtatggatt tacttgccaa atgattcgct tactagaaaa attcgctaac ttgtaatttg
    12841 atagatcaat cgataaaaga agcctttgac tggatccagt caaaggcttc tttcttttca
    12901 tcccctactt ttaaactcgt tcaatgaaca tattggctta aaaattgttg gactacttgc
    12961 tgatattttt caggatctgt cttgtatgct tccgcatgct cggctccttt tacaacatac
    13021 ttttcttttg gtcccttcgt tgcacgatag accttatcta acatttcaaa tggtacaaat
    13081 gtatcttcgt ctccatgtat aaagagcatt gggcgctggt ttttcttcaa ttgttccact
    13141 gcatttgctt caccgaaaaa gtagccagca cggacttttg tcactagact cgttacttgc
    13201 ataagcggaa atgctggaag actaaacata tcgtctagct gataagcaag ctcatcatga
    13261 acggaagaat aaccgcaatc ttcaatgatt gctttcacat tatctggtag tttttctccg
    13321 ctagtcatca taactgttgc tgctcccatg ctgacaccgt atagaacgat ttcttgcgat
    13381 tttccattgt tttctagcac tttgtttatc cactgtacat agtctttacg ctctggccat
    13441 ccaaatccaa tgtaatcccc ttcgcttttt ccatgtcctc ttgcatcagg aacaaggaca
    13501 ttgtaaccca tatcatgaaa catctttgcg taattggtca tcgtttcagc gtttcccata
    13561 tagccatgag ccacaagagc tgttttttca cttttcgttt cagcaggaag ataaatcgct
    13621 gataatttca gaccgtcttt tgaagtgatg gtccaatcgc ttcggttttc ttttgaacta
    13681 aaccatttat gtgcatccgt ttctttggat gtctgtgttg taccaggtgt atcttcgtct
    13741 aaaaagtctt tctcagaagg cacaacagca taattataaa aataattccc tgcaaacact
    13801 aacgcaacaa tcagagctaa agcgacgcct aaaaggattt tcatccaaag tttcataaat
    13861 catccatctc atttctcttt tttcatataa ccttgaatta gtataatcaa agaatctcta
    13921 ctatgcaatg ttcattttta taac
//
LOCUS       DADGHT010000077        13734 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.078, whole genome shotgun sequence.
ACCESSION   DADGHT010000077 DADGHT010000000
VERSION     DADGHT010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.078"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            137..1564
                     /locus_tag="JX887_002065"
     CDS             137..1564
                     /locus_tag="JX887_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAX1258041.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1656..2021)
                     /locus_tag="JX887_002066"
     CDS             complement(1656..2021)
                     /locus_tag="JX887_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAX1258042.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(2018..2383)
                     /locus_tag="JX887_002067"
     CDS             complement(2018..2383)
                     /locus_tag="JX887_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAX1258043.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2575..2823)
                     /locus_tag="JX887_002068"
     CDS             complement(2575..2823)
                     /locus_tag="JX887_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258044.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2822..2950
                     /locus_tag="JX887_002069"
     CDS             2822..2950
                     /locus_tag="JX887_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAX1258045.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            3007..4701
                     /locus_tag="JX887_002070"
     CDS             3007..4701
                     /locus_tag="JX887_002070"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAX1258046.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4705..4824
                     /locus_tag="JX887_002071"
                     /pseudo
     CDS             4705..4824
                     /locus_tag="JX887_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4906..5097
                     /locus_tag="JX887_002072"
     CDS             4906..5097
                     /locus_tag="JX887_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258047.1"
                     /translation="MDLLPQMQAFEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDL
                     LPQMQAFEHRLPRGYEKGV"
     gene            5475..6608
                     /locus_tag="JX887_002073"
     CDS             5475..6608
                     /locus_tag="JX887_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAX1258048.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6639..6959
                     /locus_tag="JX887_002074"
     CDS             6639..6959
                     /locus_tag="JX887_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258049.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6988..7452)
                     /locus_tag="JX887_002075"
     CDS             complement(6988..7452)
                     /locus_tag="JX887_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1258050.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7583..8836)
                     /locus_tag="JX887_002076"
     CDS             complement(7583..8836)
                     /locus_tag="JX887_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1258051.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8865..9182)
                     /locus_tag="JX887_002077"
     CDS             complement(8865..9182)
                     /locus_tag="JX887_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAX1258052.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9208..9528)
                     /locus_tag="JX887_002078"
     CDS             complement(9208..9528)
                     /locus_tag="JX887_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1258053.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9992..11407)
                     /locus_tag="JX887_002079"
     CDS             complement(9992..11407)
                     /locus_tag="JX887_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1258054.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11424..12740)
                     /locus_tag="JX887_002080"
     CDS             complement(11424..12740)
                     /locus_tag="JX887_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1258055.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12890..13588)
                     /locus_tag="JX887_002081"
     CDS             complement(12890..13588)
                     /locus_tag="JX887_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAX1258056.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT         4364 a         2789 c         2359 g         4222 t
ORIGIN      
        1 ccaaatttta taacataaaa aacctttttt aacggcattt atatgctttt tcagaaatta
       61 actgatgatt tcaaaaagaa aacatgtcat aatatttccc atattgtgca aaaaaataca
      121 aggcggaggc tctactatga ttgaagaata tattgagaaa aatattttaa gacagctgtt
      181 tttatgtggg caattctatg taaataaaga agtcaatcta gaaaagctct ccaatctcct
      241 gcatgtttgc aaaaccactt tactcaatga tatcaataac ataaaaaaag aatttgaaga
      301 acagatcgct tatacacatc gggaaaagga ccgttacact ttatattttt cagaacatat
      361 acctcgatgc aagatcatgc agcaattgtc tcaaaattcg ttgtttttaa aaacttgtct
      421 gctttatttg gaagaagatg aacctgatta tcttcaatta actgaatgtg aattcatctc
      481 tgtcagcaaa gcttattcat taaaaaaaca agtattagct tattttaatg actgcgggat
      541 cgaaatcgac cgctactccc ctcgattcac tgaaatggaa agacgtctgc tgcttcttaa
      601 tgtgtcgtat cgtttaggcg gttttaattc ttgggagcta cctgaatcgt tttttgaacg
      661 tgccgatcgt ttcattgaat ccgtaacgga aaatagtggc agattttatg ataaagaaaa
      721 taaagaaatc ttatcgattg gttttgctat cagtttccta cgccagcaag tgtgtgctgt
      781 gacaatagat tcaaaattta tcgaagaaat caaaaaacgt cctatttaca attatgtcga
      841 atcagcatgg gaaaacactg atttccaaac ctattataaa aaagaagaat tcgcctttat
      901 tttgacacta ttcaatcttt gtaattatgg tttccattct tatcagttga ttgcggaaga
      961 ctttcaacag ctacaccaag tgtttattga caatactccc gaaataaaag aactagttgc
     1021 tacctttgaa tctcacttca atcaagaatt attcggaaac caaccgttcg aacgtgcgct
     1081 gattcatctg atgcgttcgg cttgggataa ctatcaatta ttcatgccag aaaaatttta
     1141 tcttttaaat gaggaacaga caaatttata taaagaagtc cagacaattt tttccagctg
     1201 gtccagccag ttaccttatg atctacggtt gaatcctaat tgcatgcggg cttttgtgat
     1261 cgaattgagc ggaattctcc gtctgacaaa agaacatctg actatctata tcgtcacaaa
     1321 ttcggatgtt cattatctga tttatcggga agccttggaa gctgtaacta ctttcgattt
     1381 tcaagttgca ccaacaattt attcaagtat atctgatata aagaagtatg cgcagcagtc
     1441 ctcaaaccgg gtattatgtg aacgtacatt atatacacca gatgcggtcc aatatgaaaa
     1501 tattattcct atttcgatca atacgatcga tcgagctatc atttcagctg tgcaaaacaa
     1561 ataaggggct gtgacaaaaa tcatgtcaca gcctcttatt tgttgaagat gcccatttct
     1621 gtaacaatct cttgatacac gtcaggctca caacctcact tattttggac atctacgggt
     1681 ccgatctctt tatttaaaaa ataagaaatg atggttcgga taactaccaa cgccgctagt
     1741 tggaaaatat cctgcaaggt aggtttgata atcgattcga tgatcccagc tgaaacaaga
     1801 atttccaaac ttagaagtat atagcctccc aacatctttt taatagcatt gttctcgctg
     1861 actcggtcgc tttgcacttt tgtatggaca aataaatatt tcaaaaaatc cttgattgat
     1921 agacaaacac cccaaaccaa taaacagata gcaaagatat caagtcccag tacaagtttt
     1981 tcgaaatatg gaagaagaaa ctgcatcaac tctgtcgtca tcctacctct cctcttcttt
     2041 gtttttcttt gtcttctatt tcctgattca agaaataaga aatgactgtt cgaatgataa
     2101 taataagtgc aagcttcaaa atatctgtcc aagtcggctt gataactgac tcgatgatat
     2161 cagcaacgac tagtacttcc aagcttaaca aaatataact tgctagcagt tttcttgtat
     2221 ctgcattacg agtattacgt tctgcatagt ttttcttgac atgagaccaa tcaaaaagtt
     2281 tgaatagaac aagaacgatc ccgacaatta agataccgat agaacaaata tttaaaatag
     2341 caatgatcca ttctagaaat tcaattaaat ttgagcgaaa catatacgct acctactttc
     2401 ttttaatttg ttcctattct tttattgtaa aagaaagtta ccttgttcgt ctatttaaaa
     2461 gttgttctaa tgataacggt tcgcttaaat ttttcttttt cactctccca tttttctccc
     2521 tccatccata aatcgtggaa gtatccaaaa caacgtagca agttaaaata aggcttagtc
     2581 cgtcatcagc ttttcaaaga agcactgtct cggtgctttt tttgtaccca aatttctaaa
     2641 aatagaacca tacacctcct caaatctttt cttcttacct accctatttt tatttacagg
     2701 aaaatcagac acttcttctt ttttgtcaaa atttcctttt tcttctcgtc ctatcatttg
     2761 gcattctaat aaaaacgaac tatccttgga tatagaaaga gaaaacaagg aggcgttttt
     2821 catgagtaaa aaattaatca aagtcggcat cggtttaggt ttgcttgccc ttggcgctgc
     2881 atatctagga aaaaagacag gactattcga agatgacagt catttatatg atgaattcga
     2941 atcaatctag catcctattt agttgaatca ctacggacat acttggaaga cattggagga
     3001 atcacaatga gaaaaagtaa agcaataatg attggtgccg gtattgccaa tatggcagcg
     3061 gctgtttatt tgattcaaga aggcaaatgg aaaggggatc agatcacctt ttattcattg
     3121 gatgatcacg gttcaaatga tggtgcaccg accgacactg tagtggatga atattggaat
     3181 aaaaaccatc cattagaaaa ccaaaaaggc tatattgctc gaggcggtcg catgcttaat
     3241 taccgtacct atgtagattt gatggatctg ttaagtcgaa taccttctgt tactgagcca
     3301 gggatgactg ctgaagaaga tacgagagat tttgatgcaa aacaccgaac ctttgacaaa
     3361 gcacgtttga tggaaggtgg caaaggaatc attgatggcg gaaaactggg attcaataat
     3421 aaagaccgta ttcttctgac taaactgatt gctatgcctg attcagaaga agaaaaacta
     3481 gacaatatca ctatcgaaga atatttcaaa gatgatccac acttttttga aacaaacttc
     3541 tggtttatgt gggaaacaac atttgctttc agaacacgta gttctgctca agaattgcgt
     3601 cgctatatgc atcaaatgat ttatgaattc actcaaatcg aacatctagt gggcgtcaat
     3661 cgaacacgtt acaatcaata cgaaagtatt atgcttcctt tgatcgagta cttgaaagaa
     3721 caaggatgca aaatcatttt gaaccgccgt gtcactgact gggaattcaa agaaacaccg
     3781 atgcaagatg aaatcactgt gactggtttg aaaattacca atacactgac tcaagaagaa
     3841 gaatacgttg tggtcgatga agatacagca gttattttca ctaatgggtc cattacagat
     3901 tcagctactt taggagatta cgaaacacca gctgtagaaa atatggatta tggtgcagct
     3961 tctagtctct ggaaaaaagc cagtgaacgt ttctacaact tgggaaatcc tgacaaattc
     4021 tttgctgatc gagatgcaag cgaatgggtc agctttaccc tgacgacgaa aaaccatttg
     4081 ttgttgaatg aaatcacccg tatcacgact caagaaccag gaaatgcctt gaattcattt
     4141 atttcaacca caccgatcac gccgttaggc caaaaagatg tcaatatgtc tatcgtcgtg
     4201 catcatcaac cgcattttac gtctcagaaa ccaaatgaaa cagttatttg gggttatttc
     4261 ctttatccaa gacgacgtgg cgaatttgtg gataaacagt atattaaaat gaatggaaaa
     4321 gaaatgctag aagaactgat tggacaactt tcaaaagtag atcctggacc agtgaatatt
     4381 cgtgaaaaag aaacagaaat tttcgacagc gtaataaata atatccctgt ctatatgcct
     4441 tatgcttccg cgttgttcaa taatcgtgcc aaaagcgatc gaccaaaagt cattcctaaa
     4501 cattcgacca atctggcctt tacaggagaa tttgtcgagc agccttatca gatgatcttt
     4561 actgaacaaa gtgctgtacg ttctggagaa atcgctgctt tccattttgc gggtattcct
     4621 atgtcccgtc ttgtcaaaac accgcgttac gacaaagata ttcctactct agctcgtgcc
     4681 gcaaaaaaaa tgtttgaata atcaagaggt tgtgaaaaag ctgccctgca tcaagtaata
     4741 agaacaacca ggctaaaaca gcttcttatg tttttgattt ggttggactt attaccgcag
     4801 atgcaagctt ttgaacaccg tttaccaaga ggttgtgaaa aagctgccct gcatcaagta
     4861 ataagaacac ccaagctaaa actgcttctt atgtttttga cttggttgga cttattaccg
     4921 cagatgcaag cttttgaaca ccatttacca agaggttatg aaaaagctgc cctgcatcaa
     4981 gtaataagag cagccaagct aaaacagctt cttatgtttt tgacttggtt agacttatta
     5041 ccgcagatgc aagcttttga acaccgttta ccaagaggtt atgaaaaagg cgtttagttt
     5101 cgagtatgaa gaaaaatttt gtgaaaatgg ttcctcacgt ttttgcataa atttgactta
     5161 ataccgagaa actgatccct tctgtcataa cctcttttta tttatgtctg tttctttttg
     5221 aaaacaacta ttttttcaac gtttactctc ttgccaatcc aacatcatct aacggataca
     5281 actatttcaa tgattaccat tacactaaaa aatcggaaac acacctctcc gaacacaaat
     5341 acataagact atagaatgtt tcatttaaga aaaaaagcgt ttcattatca aaaaggtaag
     5401 atctccttta aaatgaaatt atctgtagta ctaataatgc agacaatttt atgaatctga
     5461 aaggagcatc tccaatgaaa gcagtcactt ggcaaggaaa acagaaaatg gaaatcagaa
     5521 acgtagatga tccaaaaata ttagaaccaa cagatgcaat catccgtatc acagcaacag
     5581 ccatttgcgg ctccgatctg catctttacc atcatggtga agcagttttg gaaaaagggt
     5641 atgttgtagg acacgaacca atgggaatcg ttgaagaagt gggatctcaa gttcaaacat
     5701 tgaaaaaagg gcaacgtgtg gttatccctt ttaatattag ttgtggtcat tgtcatttct
     5761 gcctgaatca catggaaagc caatgtgatg aatcaaatcc agatcagtta tatggcgggc
     5821 ttttcggatt tggcaagttg aacggtaatc attggggtgg tcaagcggaa tatctaagag
     5881 ttccttatgc agactctact tcatttgttg taccagataa tgatcttcct gatgaaaaag
     5941 ttttatttct atcagatatt ttgcccacag cttattggag cgttgaaaac gcaggagtaa
     6001 aaaaaggcga tacagttgtg attctaggtt ctggtccagt cggtctattc gctcaaaaat
     6061 tcgctgttat ggctggagca gagcgcgtaa tcgcagtaga tccagtacag caccgtctag
     6121 ataaagcggc taattacaat ggggttgaaa cttatttctt agaagacacg gcacaagctg
     6181 gaacagaatt gtatgaactg gctaaaggtg gcgcagatgt cattatcgat tgtgtaggaa
     6241 tggacggatt agagcctgtc aaagaaaaag cgaaaaattt agtaagctta caaagcggca
     6301 caatctctcc attacagatg gcatcgcaag ctgtcaaaaa atttggaaca gtccaagtaa
     6361 ctggtgttta tatgactcca gcttcttctt acccgctgca agaatttttt atgcgggata
     6421 tcgctgtcaa gcatggacag gcaccaatta tccatctaat gccaaaaatt tacgcaatga
     6481 ttgcagaagg actattcgat cctacacaaa tcattactca ttcgctgcca ctatcagaag
     6541 cagcacaagc atatgagatc tttgacaaaa aagaagataa aaatataaaa gttgttttga
     6601 aaccttgaat tcagtaaaaa atacaggtga ttttctttat gcccaaaatc aaacgaaata
     6661 cccatgagat cgaaatagga aaagaagaag atatcgaaat acgaggacgt cgcttccgct
     6721 tctatttcca aaatcgttac acattgatct cactggctgt cgatttatta accgggattt
     6781 tctatatttt tggaagcctt gcttccttaa ctaaaatccc cgatcgatat ggcacctatt
     6841 tttatttggc tggtgctatt ttcttgacga ttcgtcctat tctcagaatc gtaaggaaca
     6901 tttttattta cgacgaaaaa aaagcaatga agagaacaag caaaaaaaaa gaggcatgag
     6961 aatttttcaa atctcatgcc tcttttttca ccctatcgta tcactttgat acagacgagc
     7021 ggtcgtccca ctttcttcct tgaccattgt caaaaatgtc cactcgtatc gttcataaaa
     7081 cgtggtatga tctgtaatta agtaaagttt ttcgtaccca agttgatgca tttcttttct
     7141 gatttccgct aatatccgct tggctatccc ctgcttacgc ttttccggtt caacaaacag
     7201 ggcacaaaga tttggtgtca gatcagggcg gttatggaag tcgttttcaa tgacgcccgc
     7261 tcctccgacg atggtttctt tttcatctaa gaccacatac cattgaggaa tactttcctt
     7321 attagcgatt ccagtacgaa tactttcctc atacacaaca gcaggaactc cccattttga
     7381 tgaaaaccaa ttcgcgcttt gttttactaa ttctgggtgt tctcttaatt tgatccagtt
     7441 atatgtaacc aatgtttaaa cctccgacta aaataaaacg tttacaaaaa ttatacaagt
     7501 ctttatgaaa attagcaatg acaacaatag tgatgtaaaa aaaaaacgga aaacaatcac
     7561 ttgttctccg ttttttgatt aatcaagcat ctaaagcttc ttttcttctt tcttggatcg
     7621 tagctacctt gacgaacggt agatagatca aaatagaaag aaccaaattg acagcggcta
     7681 gtacaccacc tgcaatactt tttgttgcca atacaccgcc aataattggt ggagttaccc
     7741 atggaggcat aacggtagct gctggcacta aacctgtaga agtcgcaaag taagcaacac
     7801 taactaagac cattggtgtc aaaataaatg gaatgaacat gatcgggttc aacacgatag
     7861 gtaacccaaa catcgttggt tcattaatat tgaagacacc tggcgcaatc gacaagtttg
     7921 ttacaaccat atatggtttg tttttacgtc ctactaaata aatagctaac agtaaaccta
     7981 aagttgcacc tgttcctcct aagttgacaa agctgtcaaa gaaaggtttg ttcacgataa
     8041 acggtgcgct atgcccagct gcgattgcat taacgtttgc ttcaatggct ggcgcattga
     8101 ttgtttgcat caaaggatcg accatattcg ctccgtgtaa accaaagaac cataagaatg
     8161 gtgtgataaa tgcaagcagt aaggcagatg gataagagtt tgcaagtccc ataaatggtt
     8221 cttggaccac tgtatagaaa gaacctacga tatcatcaac accgaatgca gcaaaaattg
     8281 cagcaactaa agcaaacgca gagatagtga tcattgctgg tagtaatgaa gcaaatgctt
     8341 ttgcaactgc cggtggcaca ccatcaggca ttttgatgat caatttttca tttccgctta
     8401 aacgtacaaa gatttctgtt gaaataatcc caacaataat agcaataaac aaaccgtttg
     8461 agctcatacc taatgctccg cctaaagcga agaaagagcc taaagaaatc acacctgcgg
     8521 aaacaccgtc ttttcggtag ccgttagcta aatgataagc aagcaagaaa gcaatcaaga
     8581 cagaaagaat ggcaaatgta ccgttccaag cagcagcccc gaatcctttc catgattcac
     8641 caccaaaaat tgagttcatc aattcttgga acccgggaat cggtaagtta ttgatcatta
     8701 ctgctaatgc tcctaagatc attaacggca tactcaccat aaatgagtcc cgaatcgcaa
     8761 ctaaatgccg ttgtgcacca atttttgatg ctacaggtat aaaatgtttc tccataaatg
     8821 caacaaattt atccataaat cttccctctt ttctttactg tagattacgc gttcaatcga
     8881 cgatacagat caatgatctc ttttgctaaa tctgtaaaag ctatagatgt catcagatga
     8941 tcttgactgt ggaccgtcaa aagcgtgact tcaacgtgat ttccttgtgc ttcttgtgtc
     9001 agcatctctg tttgagagtg atgtgcttgg actaaagatt cctctgcatc tttgattttt
     9061 tcatctgcta aagtgaaatc accttttttc gcagcagcaa tcgcttccat tgcatcgctt
     9121 tttgcatttc cgccaaacat gatcagaccc atgatggctt ctagattttt ttgatcttcc
     9181 atttattgta tcctccgata atttttatta tttgtttatt agtttttctg cttggtcgag
     9241 tactttttca ccattcatca tgccatagtc agccatattg attacatcta aaggaatgcc
     9301 tttaggtgct agcttttcag caaattgatt ttgcataaag cgtacttgcg gtcctaaaag
     9361 taaaacgtct acatttttag attctagttg attatccgca tctgaagcag atacagcaaa
     9421 gatgtctgct tccattcctt ttgcttctgc tgccttttgc atttttgtga ctaggagact
     9481 tgtactcatt ccagctgaac atacaagcat gattgttttc ttttccattt taaacacgtt
     9541 cctttctata cttacacttg tatataagca agtagcgtgc caactttaaa agcgctttaa
     9601 aaagttgata tcatcacatt taaggtctat accaagttgc atacacacta aaaaagaaag
     9661 cgcacactaa acacacaaat taatttttat tacctttttt cttttaacgt gcacaaaaaa
     9721 agttgtgaca caaaacttgt cacaactttt ttcaaataaa cggtattcaa aagcttgcat
     9781 ctgcggtaat aagtccaacc aagttaaaaa cataagatgt tgtttttact ttgctattct
     9841 tattacttga tgcaggacag ctttttcaca acctctcaat aaacggtgtt caatcagctg
     9901 accctgggta ttagctcaaa acgctggatt cacaacctct tttatttcaa ataaccagta
     9961 aatacaatga acatctacaa aaaacttcta tttatttata gatttcgtca ggcaaatcca
    10021 attctctctt atcaatcaaa gtctgatacc acgaagcaga ttttttcaat gttctgcttc
    10081 gttcatcgtt caattcgatt cgaactaatc catatcgatt cttaaatgca ttcattggtg
    10141 acacacagtc agtgaatgcc cataacatat agccttcgca atttgcgcct tcttctgttg
    10201 ctttgatcaa gtaatgcaaa tgctgtccga taaattcgat acggtaatca tcttgcacga
    10261 ttcctttctc atccatatac tgttcttcat attctcttcc cataccgttt tctgttatca
    10321 gccaagggat attatgataa ttttctttta gatacatggc tatatcatac atgattttcg
    10381 gatagatttc ccatcccctg gaattattca ttttcttccc aggtaaatca aagacttcat
    10441 aatatcgttc aggatggaaa ggtgtctctt cattccattg ataacgaggg gcgcgaacgc
    10501 gtttaggata atattgattg attccaagga aatctactgt atgatgctga atcgtttcta
    10561 aatcctctgt tgcaggatcg aaataaatcg attgtttttg acacaactcc aggaactctt
    10621 ctgtgtagta tccttttacc atcggatcaa aaaatactcg attataaaac aaatcataca
    10681 tataagcagc tttttggtct tctggagaat tggatcgagc atagaccatt tcaggattta
    10741 aaatacagcc aatccttcca ccataatttc cgctgcggta aatctctact gctttagccg
    10801 ttgctaaaac tttatgataa ttccacatca tccacttttt tgtgttttgt tcatgcggcc
    10861 agcgaacagc atccaaatag caacgcgttt ggggaacgat tggttcgttg aatgtaaacc
    10921 agttttttac cctatcaccg taacgatcaa aggcaatttg agcatactta gcataaaaat
    10981 caactacttt tcttgaagac cagccatcat atttttccaa aagaaaagct gggacttcat
    11041 aatgttccaa acaaatcatc ggttctacgt ctgcttcgat caaagagtcg atcatttcac
    11101 ttatatgctg agcatattct tcatctacta tacagttctc ataatcagta aaaaaacgag
    11161 cccaattgat agaagtccga taatgtgtca gatggatgga tttcatcaga tccacatcct
    11221 gctggtattg ttccataaaa ttagttgcta cggctgggcc atacccatta tgccaaacaa
    11281 aatgttcatt tttataccag ctatctataa acgaatcctg tccttctttt tttcctttcc
    11341 aaccttccgt ttgccaagca gaagatgcag caccaagaat aaaatttttt ggaatagtaa
    11401 ttttcatgat ttcctcctgt tttttagatc ccatcatttt ccacacgatt tgctactttt
    11461 acaaatggca gatagatcaa aatagaaaca ataatacaaa caagttgcgt aataactgca
    11521 ccgatatttc ctgctgttgc cagataagca ttgacgatcg gcggcattgg ccaagggacc
    11581 attacaactg ctttcgccgc aaatcctaaa gcggttgcaa aataaccaat cgttccagtg
    11641 ataagaggcg ttaagataaa cggaatagct aaaattggat tcagcatgat cggcatacca
    11701 aaaataactg gttcattgat gttgaagatc ccaggagcaa gggataactt ggtgatttgt
    11761 ttcatatctt cccgttttcc aactaacaat actgcaatca gtaaaccgat cgtgactcca
    11821 gacccgccca tactcatata catatcccaa aatggcatag taataatgtt cggtacttct
    11881 tttccagctt caaaagcttc cgtatttaca gcaattgccg ctaaaagcaa cggttcccgt
    11941 atcggcttca ccatttgatt tccatggata ccaatcaccc aaaagacttg cgcaataaac
    12001 atcaatagca aaatacccgg taacccttgt acgacacctt ctaatgggcg ttgtacgaca
    12061 ttgtaaatga tatcataaag gtacattcct gtaagttctt tgatgataaa tcccgcagcc
    12121 gcgatacccg atacagtcag aatcgtcggg aataaagcag aaaaactagc agaaacattc
    12181 gttggcacgg tatcaggcat tctcagctgt agtttcttct gtttcctcaa ccagcaataa
    12241 agttcaatag aaaggatgga gaccaacatt cccaaaaata accctttcgt atctgtatat
    12301 tgtttagcca atacgttttc tactataaca gtctgatttt cattcactaa ttcataaaca
    12361 gttggattaa cagataaata agacatcact gcgatgatac cagggaatac accatccact
    12421 ttattcagct tggctaattc gatccctatc agaaaaacag catagatggt caagaaactt
    12481 agtgtgacat agctgatggc agatgcgata ggctttaatt cttctaaaaa acgcaagaaa
    12541 cttatctgtg ctaagccatt ttccgagtca aagaccattg ctgaaaacaa tgtgccaaaa
    12601 gcacccgtaa taattaccgg aatcaatgca gcaaatgcgt tttttatcac catgatatac
    12661 cttaaattat tgattctcgt tgccacgttc cctaaaacat tggctaattt atccataaaa
    12721 ctcattccag atcccctcat tcctgcttct tctccttgac gtcatctctt tttgtctatt
    12781 agtcagcgct tacatttcga tgaacagaaa ctatttactc ctctttttta ccaaatataa
    12841 aacaaaaatt catctgatgt atttatcata aaatacatca gatgaactgt caattagttt
    12901 ctttttctcc tattattttc tgtaattctc tccgatttat tgccatatgg acagtcattg
    12961 catcaaacgc agcaagtgca ttccgccttt cgatggcctg aacgatctct gtatgaatat
    13021 cgatcgtctc gattttcaga tgctggatat cataattttt attaaacaaa gcaattgatt
    13081 cattaatgat tgggataata tgcagcaagg ctacgtttcc gctagcttct gcaatcatcg
    13141 tatgaaaatc gatgtctaat tgaacatgtt cttgtgtgcc ttctcgaaaa gaagtttcaa
    13201 tcttttgcgt taattttttc atttggacga tttgattctt cgttgcatat tccgctgcca
    13261 aacctgccat cttaggctcc aataaatatc tcagttcaaa taagtctcgt atcatccgat
    13321 cctgatcttc aatcaaagaa aaaccgagtg ggtcattggc aatccctcgc ttatcactga
    13381 caaatgtccc cgctccttgc cgaacttcaa ggatattcct ggaagctaga gcccgcacag
    13441 cttctcgcac cgtgcttcgc cccacctcta aataatcgga caattcatat tcattcggca
    13501 gtttatctcc tacttgcaac tgcatttcct ttaaatatct aaggatcttg tcagtagtta
    13561 cttctactag ggttttattt tcttccaaac cacatacctc cttttcatct gatgtatttt
    13621 ttcgtaatta ttataacacg tttgaatcat ctgatgattt tttgtataca aaattgatta
    13681 atccgttcat agacatacaa acgaagaaga tatttaccat aaaaaagact agga
//
LOCUS       DADGHT010000078        13723 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.079, whole genome shotgun sequence.
ACCESSION   DADGHT010000078 DADGHT010000000
VERSION     DADGHT010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13723
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.079"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            99..341
                     /gene="yaaA"
                     /locus_tag="JX887_002082"
     CDS             99..341
                     /gene="yaaA"
                     /locus_tag="JX887_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAX1258057.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            328..1452
                     /gene="recF"
                     /locus_tag="JX887_002083"
     CDS             328..1452
                     /gene="recF"
                     /locus_tag="JX887_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAX1258058.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQVQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            1449..3395
                     /gene="gyrB"
                     /locus_tag="JX887_002084"
     CDS             1449..3395
                     /gene="gyrB"
                     /locus_tag="JX887_002084"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAX1258059.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            3415..5886
                     /gene="gyrA"
                     /locus_tag="JX887_002085"
     CDS             3415..5886
                     /gene="gyrA"
                     /locus_tag="JX887_002085"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAX1258060.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            6122..6421
                     /locus_tag="JX887_002086"
     CDS             6122..6421
                     /locus_tag="JX887_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAX1258061.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            6471..6983
                     /gene="ssb"
                     /locus_tag="JX887_002087"
     CDS             6471..6983
                     /gene="ssb"
                     /locus_tag="JX887_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAX1258062.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            7009..7245
                     /gene="rpsR"
                     /locus_tag="JX887_002088"
     CDS             7009..7245
                     /gene="rpsR"
                     /locus_tag="JX887_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAX1258063.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            7388..9361
                     /locus_tag="JX887_002089"
     CDS             7388..9361
                     /locus_tag="JX887_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAX1258064.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            9367..9819
                     /gene="rplI"
                     /locus_tag="JX887_002090"
     CDS             9367..9819
                     /gene="rplI"
                     /locus_tag="JX887_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAX1258065.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            10093..11460
                     /gene="dnaB"
                     /locus_tag="JX887_002091"
     CDS             10093..11460
                     /gene="dnaB"
                     /locus_tag="JX887_002091"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAX1258066.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            12240..13532
                     /locus_tag="JX887_002092"
     CDS             12240..13532
                     /locus_tag="JX887_002092"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAX1258067.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT         4571 a         2475 c         3022 g         3655 t
ORIGIN      
        1 atcgtcttat atggaaaaat atatggataa atttgtttta ttgcgaaaaa aaaggtataa
       61 tagagtatac ttttaataat gaaaatgagg gatgggcatt gaaacaacaa gtcattctaa
      121 atacggaatt catgacgttg ggccaaatgt tgaaagaagt cacagttatc ggtagtggcg
      181 gacaagcaaa atggtatttg gcagaaaaca ctgtgttagt cgatggcgaa ccagaaaatc
      241 gtcgtggacg caaactttat cccggcatga tggttgaagt tccagaagta ggaacttttt
      301 ttatggtaaa aaaaggaaac gacgataatg aggctgaata agctgtattt aaaaaattat
      361 cgaaattacg aagagctgaa catcgaattt tccaagaacc tcgtcatctt tttaggagaa
      421 aatgcgcaag gaaaaacgaa tcttttggaa agtatctacg tattagctat gacgcgaagt
      481 catcggacaa gtagtgagca ggaattgatt ggctggactg acgatcaggc gatgattcaa
      541 ggagagatca caaaaggttc atccactctt ccattagaaa tcttattatc taaaaaaggc
      601 cgaaaaacca agatcaacca tatcgaacaa aaaaagttaa gtacttacgt gggacaaatg
      661 aatgtcattt tatttgcacc agaagatctt tctttagtaa aaggcagccc gcagatcagg
      721 cggaagtttt tagatatgga attaggccag atcaatccaa tctatcttta tgatcttgtc
      781 caataccaag caattttgaa acaaagaaac cagtatttaa agcaattgaa tgaaaaaaaa
      841 caaactgatt tgctttattt ggatattttg tccgaacaac tagcagcgtt tggcagcaaa
      901 gtattgaaag caagagcaca gttcgtcaag cgattggagt tttgggctaa ttctttgcat
      961 cagcaaatca cccatcaaaa agagcagctg gaaatcgagt atctcaccgc agtcgattct
     1021 ttagaaacac atacgcaaga gcaagtccaa gaacaatttc tcgcactttt gaaccaaaat
     1081 aaaaagaaag acctttttcg gggaacaacg acagttggtc ctcatcgtga cgatctttcc
     1141 ttttttatta atcagaaaaa tgtgcagact tatggatcgc aaggacagca aagaacaact
     1201 gcactaagtg tcaaattagc agaaatcgat ttgattaaag aagagacggg ggaatatcca
     1261 atccttttgt tagatgatgt gatgagcgag ctggatgata gtcgtcaact ccatctgcta
     1321 gaaacaatcg aaggaaaagt tcaaacgttc ttaacaacaa cgacacttga ccatgtaaaa
     1381 aataaaatga ctgttgaacc tgagattttt tatgttcaac aagggaaact aaaaggagaa
     1441 gaaactgaat gacagaagaa agaagtttag tagaacgcgc taaagagtat gatgccagtc
     1501 agattcaagt acttgaagga cttgaagccg ttcgtaaacg acctggcatg tatatcggtt
     1561 cgactagttc tgagggtctg catcaccttg tttgggaaat tgtcgataat tcgatcgatg
     1621 aagtattagc aggttttgca acgaaaatcc atgtgattat tgaaaaagac aacagtatca
     1681 ccgttattga cgacggtcgg gggatacctg tagatatcca ggcaaaaact ggacgtcctg
     1741 cagttgaaac ggtctttact gttttacatg ctggaggaaa attcggcggt ggtgggtaca
     1801 aagtttctgg tggacttcac ggagtaggat cttctgttgt taacgcgctt tctacacagc
     1861 ttgatgtcaa agtatacaaa gaaggaaatg tgtactatca agaatatcgt cgtggagctg
     1921 tagtggacga cttaaagatt atcgaacaaa cggatcgcca tggaacaacg gttcacttta
     1981 cgccagaccc tgaaattttt acagagacaa ctgagtttga tttttcaaaa ttggctaccc
     2041 ggatccgtga acttgctttc ttgaaccgcg ggatgcgtat atcgattgaa gacaaacgag
     2101 aagaagaacc agtcatcaat gaataccatt atgacggcgg gattaaaagt tatgtcgaat
     2161 acttgaatgc aaacaaaacc gtgatttttc cagaacctgt atatttggaa ggtgaacagc
     2221 aagatatcgc agttgaagtc tctatgcaat atacagacgg ctaccattcc aatatcatga
     2281 gttttgccaa caatatccat acgtatgaag gcggaacaca tgaatcagga ttcaagactg
     2341 ctttaactcg tgtgataaat gattatgccc gaaaacaaaa gctgatgaaa gaaaatgacg
     2401 acaacttgac cggtgaagac gtgcgagaag gattgacagc tgttatttct atcaagcatc
     2461 ctgaccctca attcgaagga caaacaaaaa caaaattggg caattccgaa gtacggacag
     2521 tcactgatcg gttatttagc gaacatttca tgaaattctt gctggaaaac ccaagtgtgg
     2581 gccgtcaaat tgttgaaaaa ggattactag cttccagagc tcgtctagca gcgaaacgtg
     2641 cgcgtgaagt aacgagacgt aaaggtgctt tagagattag taatctgcca ggaaaattag
     2701 cggactgctc tagcaacgat cctgaaaaat gcgaattgtt catcgtcgaa ggagattcgg
     2761 ccggcggatc agctaagcaa ggtcgtaatc gagagtttca agccatcttg cctattcgtg
     2821 ggaaaatctt gaatgttgaa aaagcaagca tggacaagat cttggcaaat gaagagatcc
     2881 ggtctttatt tactgctatg ggtacagggt ttggagaaga ttttgatgta tcgaaagctc
     2941 gctaccacaa attagttatc atgactgatg ccgatgtcga cggcgcgcat atccgtacat
     3001 tgctgctgac tcttttttat cgttacatgc gtcctattgt tgaagctgga tacgtctata
     3061 ttgctcagcc acctttatac ggggtaaaac aagggaagaa tattacgtat gtacaaccag
     3121 gaaaaaatgc agaagaagag ttgaaacaag tcgttgcttc acttcctgcc tcaccaaaac
     3181 caagcgttca gcgttataaa ggacttggag aaatggatga tcatcaacta tgggaaacaa
     3241 ctatggaccc aagcaatcgg atgatggccc gcgtcagtgt ggacgatgct attgcagcag
     3301 atcagatatt tgaaatgttg atgggggatc gagtagaacc ccgtcgtgca ttcatcgagg
     3361 aaaatgcaca ctatgtgaag aacttagata tttaatcatg aaggaggaaa aagaatgagt
     3421 gaagaaatca gagaaaacat ccatgatgtc aatctaacca gcgaaatgaa agactccttc
     3481 atcgattatg cgatgagtgt tattgtcgca cgtgcacttc ctgatgtcag agatggtctg
     3541 aaacccgttc atcgccgtat tttatacggc atgaacgaat taggtgtaac accggataaa
     3601 gcccataaaa aatctgccag aatcgtcgga gatgtcatgg gtaaatacca tcctcatgga
     3661 gactatgcga tctatgagtc aatggtacgg atggcacagc cattcagcta ccgttatatg
     3721 ctagtggatg gtcatggaaa ctttggttct gttgacggtg acggtgccgc cgctatgcgt
     3781 tataccgaag cacggatgag caaaatcgct acagaaatgc tgcgtgatat caataagaac
     3841 actgttgatt tccaaagcaa ctatgatgat acagaaaaag aaccagttgt actacctgct
     3901 cgcttcccga atcttttagt gaacggaaca acggggatcg ccgtaggtat ggccacgaat
     3961 atcccacctc ataacttgtc tgaggtagta gcggctatcg atttgctgat ggataatcct
     4021 gatgtgacga ccaatgaatt gatggaagta ttacctggac cagattttcc aacaggtggt
     4081 ttggttatgg gaaaatcagg aatccgaaga gcgtatgaaa caggtaaggg ttctattacc
     4141 gtacgtgcaa aagttgagat tactgagatg ccaaatggta aagaacggat catcgtgaca
     4201 gaattgcctt atatggtcaa taaagcaaaa ttgatcgaac ggatttctga actgcacaga
     4261 gacaagcgta tcgaagggat cacagatttg cgggacgaat cttcccgtga aggtatgcgg
     4321 atcgtcattg acatccgtcg tgacgccagc gcatctgtta tcttgaataa cttatataaa
     4381 ttgacatcct tgcaaaattc atttggattc aatatgttgg cgatcgaaaa aggtgtgccg
     4441 aaagttttga gcttgaaaca aattcttgaa aactatatcg aacatcagcg cgaagtcatc
     4501 acaagacgga cagtctttga aaaagaaaaa gcagaagcaa gggcacacat tttagaaggt
     4561 ttgcgtattg ctttggatca tatcgatgaa atcattgcga ttatccgcgg gtctaaatca
     4621 gatgacgaag caaaagcgac gatgatcgaa cggttcgatt tatccgatcg ccagtctcaa
     4681 gctattttag atatgcgttt acgccgattg accggtttgg aacgggaaaa aatcgaaaat
     4741 gaataccaag aactcttaaa actgattgaa gatttaactg acattctggc aagaccagaa
     4801 cgtgttacag aaatcatcaa gaatgaatta gcagacttga atcaacgatt tggtgataaa
     4861 cgacgcacag aattactagt cggtgaggtc ttaagtctgg aagatgaaga tttaatcgaa
     4921 gaagaagaaa tcgttattac attgacaaac aatggttaca tcaaacgttt ggcaaataat
     4981 gaattcagag ctcaacgaag gggtggacgt ggtgtccaag gaatgggtat ccacaatgac
     5041 gacttcgtca aaaatctggt ttcttgttct acccatgata cattgttatt ctttacgaat
     5101 aacggaaaag tgtatcgggc aaaaggatac gaaattccag aatacgggcg cacagccaaa
     5161 ggaataccaa ttatcaattt actaggtatc gattcgagtg aaagcatcca ggcaatcatt
     5221 gcggtgacgg gagaagcaga agaaggccac tatctcttct ttacgacgcg tcaaggtaca
     5281 gtaaaacgta cttctgtcac tgcttttgct aacatccgaa gtaatggtct gatcgcaatt
     5341 ggtttgaaag aagacgatga gctcgtcaat gtgctactga cagatggtca atctaatatc
     5401 attattggaa cacataacgg ctactctgtc actttcaaag aagaagcagt ccgcgatatg
     5461 ggacgtacag cttccggggt tagaggaata cgcctgcgtg aggaagatta tgtcgttggg
     5521 gcagccttaa tgaaggaaga tcaagaagta ttagtgatca cagaaaaagg ttacggaaaa
     5581 cggacaaaag tatcggaata tccagtgaaa ggccgcggag gtaaagggat caaaacggcg
     5641 aacatcactg aaaaaaatgg tccactagct ggattgacca ctgtttctgg agatgaagac
     5701 atcatgctga ttacagataa aggtgtcatt atccgtttca acgtatcgac tgtttctcaa
     5761 actggacgtt caacattagg cgtacgtttg atgaagatgg aagctgatac gaaagttgtc
     5821 acgatggcag cagtcgaacc agaagctgca gaacaaacag ttgaagaaca aggatcagaa
     5881 gaatagccat caagactaat tgtgtaagct agcaagaatg accgattaaa aaatctggtt
     5941 attcctgctg gcttttttga ttagttgaat ttctcttaaa atattcgaaa ctgttcattc
     6001 tgtattgctt ttgaccaaaa tagagtgtat aatcagagct tgtgagtagt ctaattaatt
     6061 agataactct ccttgctctt aggaacctaa gagccgaaag tccacaggga ggtgaatatc
     6121 aatggaaaac acgaaatatg aaatcatgta cattattcgt ccaaacattg atgaagaagc
     6181 aaaaactgct ttaatcgaac gtttcgatgc aatcttgaaa gataacggag cagaagttat
     6241 cgaatcaaaa gattgggaaa aacgccgttt cgcttatgaa atgaacggtt accgtgaagg
     6301 tatctatcac atcgttaaag tatcttctcc atcatcagca aatgctgtca atgaatttga
     6361 ccgtcttgct aaaatcaacg acgatatcat tcgtcacatg attgttaaag aagaagctta
     6421 attgttgttt catgtgaaac aatagaaaac gatgagagga gatgactatt ttgattaata
     6481 atgttgtatt agttggacgt ctgacgaaag atccagattt gcgttacaca gcaagtggta
     6541 cggcagtcgc aacatttact ttggctgtga atcgtaattt tacaaaccaa agcggcaatc
     6601 gcgaggctga ttttatcaac tgtgtgattt ggcgcaaatc agcagaaact ttagcaaact
     6661 atgctcgtaa aggaacactt ttaggtgtta ctggacgtat ccaaactcgt tcttatgata
     6721 atcagcaagg acaacgtgta tacgtgacag aagtagtagc tgacaacttc caattgctgg
     6781 aaagtcgttc tgcatctgaa aatcgccaac aaagcggcgg attccaaagt tctggtcaat
     6841 cagctggcgg atttggcgga aacaataact ctaatcaaac atctcaatca tccaacggta
     6901 tgcctgattt cgaccgtgat acttctgacc cattcggctc aagttcaacg atcgacattt
     6961 cagacgatga tttaccattc taaacgaatt tgataggagg gaaatagaat ggcacaacaa
     7021 agaagaggcg gacgtaaacg tcgtaaagta gactacattg ctgctaacca tattgaatat
     7081 atcgattata aagatatcga attactaaaa agatttattt cagaacgcgg taaaatcttg
     7141 ccacgtcgtg taactggtac aggcgctaaa aaccaacgta aaattactgt tgcaatcaaa
     7201 cgcgctcgta tcatgggctt gctacctttc gttagcgaag actaataaat cctaggaatt
     7261 gaatgactga tccttttgat cagctattca attccttttt ttctgtaaaa ataacctcta
     7321 ttcgtttagt cgctcgaatg acgaaagtta tggtaaaatc aaattagtca tatatgggag
     7381 gaaaattatg gaaaataaaa acaatcattt atccccgaaa cctctcttcc ttatcctgtt
     7441 tatattaatc gaagtattgg tagtcttaat tttaccattt cgttttgtta gcgcttcggt
     7501 cattctattg atgaatttat ggggtgttcg ctattggttg aaaatgaaac gttggcttat
     7561 tttaaataaa cgtgaaaaaa tccagcaggc ttcgactgta gctgaaacca atctagctta
     7621 tgtctcagaa gtcatgcctg taggagtgat tgcttatcag ccatcaagcc aaaaaatcga
     7681 atggctcaat ccattagcat tgaaaatcaa agatcaaagt ggattaacag aggaagaatt
     7741 gctagatact ttttttactg caaaagaaaa aaagaaaaac caagtctatc tagcagataa
     7801 aacatttcag tttgatatgg atacagtaaa gggtgttgtt tattttaatg atattaccca
     7861 aaaccagttg ttaaaactcc atcagacgaa cagtcagccg gtgattggta ttttatctat
     7921 tgataactat gcagatgcca ttgataaatt ggatgacaaa gagatttctt atttgaactc
     7981 tttcgtcact acactagttt ctgactggat gaatgaatac catgtctttt tcaaaagaat
     8041 caacgcagaa cggtttttct tcgtagcaca gatgatcgat ctgaaaaaga tgatggataa
     8101 aaaatttgat ttgctggatc gctttcgagc agaagctgaa aaacagagct cgcctatcac
     8161 ccttagtatg gggattgctt atggctcaag aaccctcgat gaaatcggtg gagaagctca
     8221 gaataattta gatgttgctt tagtccgtgg aggcgaccaa gttgtcgtga aagaggtaaa
     8281 agaaggagca aaacctgttt attatggggg gaaatctgct aagaatgtca aacgcacgcg
     8341 tgttcgttct cgagcgatga gtaccgcttt gcgtcggatt tttgatgaaa caggcgatgt
     8401 gtttatcatg gggcacaagt ttccggatat ggatgcttta ggctctgctt ttggtgtcag
     8461 ttgtctggca cgcttcaacc agaaaaaagc ttacatcgtt atcaacgaga acgagatcat
     8521 tccagatgta gaacggtgtc ttgaagaaat ccataagcat cctgaattag aaatgcaact
     8581 aatctctcca gaacgtgcca tagagctgaa aaaagaagag gacctcctcg tgatggtgga
     8641 ttaccataaa ccttctctat cgatctctca gggcctatat gagcaatttg ataagattgt
     8701 gatcattgat caccatcgtc gtggggaaga gtttccaagt aaacctctgc tgacttatat
     8761 cgaatcttca gcttcttcag cttcagagct agtttctgag ctgatccaat accaaagcag
     8821 caaaacaaat cgcttagatc gttttgaggc cacattattg cttgcaggga tggttgtaga
     8881 tacaaatagt ttcaatgtcc gtacaactgc acgaactttt gacgttgcca gctatttaag
     8941 gtcttgtgga gcagacgcat ccttagtaca atatttattg agctcggatt tagcgacata
     9001 cttggagatc agcaatttga ttgctggaag cgactatgtg acttctgata ttgttgtggc
     9061 ggcagggaca gacgaaaaag agtataatag tgttatagca gcaaaaacag cagatacatt
     9121 gctttcgatg atcaatatca atgcagcttt cgtcattaca aagcggacag acggcttgat
     9181 tgggatcagt gccagaagta ccggcacgat caacgtccaa atcatcatgg aatccttagg
     9241 tggcggagga cacttcacaa acgcagctac tcaactggaa aatacgacag ttgaggaaac
     9301 aaaacagaag ctatttgctg caatcaaaga aaatatgaat caaatatatg ataaggagta
     9361 atccaaatga aagtaatttt tttacaagat gtaaaaggaa aaggtaaaaa aggggacatc
     9421 aaagaagttc cagcaggtta tgcacaaaat tatctaatca aaaataactt ggcaaaagaa
     9481 gcaacgaaaa gcagtatcag tcagttagca ggacaaaaga aagcacaaga aaaacacgaa
     9541 gctgaaatct tggaagaagc taaaaagtta aaagaattct tggaaaaaga agatactgta
     9601 gtcgaattga aggcgaaagc aggggaagac agccgtttgt ttggttcgat cccttcaaaa
     9661 caaattgctg aagggttaaa caaacaatac aaaatcaaat tagataaacg aaaaatcgaa
     9721 ttagaaaatc cgatccgttc actaggctac acaaacgtac ctgttaagct tcatcatgag
     9781 gtgacggcta cgatcaaagt tcatgtcgta caagaataac aaatcttgat agcgatgttc
     9841 agctggtaag tataaccaga aggaaaaaag acaaaccgaa atttatctga gaaaacagct
     9901 gcagcaatga aagcaaaagc tgcaaatcga tttcagattg atttcggttt cttttttggg
     9961 aacagcaaaa tagcataaag aaaacgagta taataaaaga gaactatttt tttattacac
    10021 tttcggtacg aatgatgact tttctctcat tttcttgtaa aatgaagcaa ttgaagacaa
    10081 ggagcgatac gtatgaatga agtgtggcag gatcgaatcc caccgcaaaa tattgaagct
    10141 gaacaagcgg ttttaggctc tgtttttctt gacgcagaaa cgatcattga tgccatggag
    10201 tacatagagc caaaagactt ttatcgtcgt ggccatcaaa ttatttttga gacaatgatc
    10261 gagttaaatg atcgtaatga agcgattgac gtggttactg tcaaagaccg gctggaacaa
    10321 gccaatttgt tagaagatgc cggtggttta agttatctct cagacttggc attagcagtt
    10381 ccgacagcag caaatatcgt ctactatgcg aaaatcgttg aagaaaaatc attgctgcgt
    10441 acattgatcc agacagcaac aggaatcgtt acgaaaggat tcgagcaagg agaagaagtt
    10501 caaacaattt tagatgatgc cgaacgcagt atcttggagg tttcggaaaa aagaaatcga
    10561 agcggctttt tatctattgc tgaagtactg aactccacga ttgaaaatat cgatcgacta
    10621 gctcaaaaca atgaagaaat cacaggtcta ccaactggct atcaaggtct ggataaaatg
    10681 acagcaggtt tccagcccga agaactaatc attcttgctg cacgtccagc ggtaggtaaa
    10741 acagcgtttg cattgaatat tgctcaaaat gtaggaacaa aaacagatcg ttctgttgcg
    10801 atatttagtt tggaaatggg ggcagaatct cttgtaaatc ggatgctttg tgcagaaggt
    10861 tcgattgagg ccagccattt acgtacaggt cagctttcgg aagaagaatg gtcgaatctg
    10921 atcgttgcga tggggagtct ttctcgagca aatattttta tcgatgatac accagggatc
    10981 aaaatctctg aaatccgtgc gaaatgtcgg aaactagcgc aagaaaaagg caatctaggc
    11041 ttgatattga tcgattattt gcagttgatt gaaggtaacg gtaaagagaa ccgtcaacaa
    11101 gaagtatcag atatctctcg ccaactgaaa aaactggcga aagagctgaa agtacctgtc
    11161 attgctcttt cacagttatc tcgtggagta gaacagcgac aagacaaacg accagtgcta
    11221 agtgatattc gtgaatccgg atcaattgaa caagatgcgg acatcgtagc cttcttgtat
    11281 cgagatgatt attatgaaag agaaggcgga gatgacgatg atggaaacga gccaaaaaat
    11341 gacaacgtca tcgaagtcat catcgagaag aaccgaagcg gtgcacgagg aacagttgaa
    11401 ctactgttta tcaaagaata caataagttt tcgtcgcttt cgccaagaga agaattttaa
    11461 agaagaggtt gtgagccttg agcaatcccg agagctctcg taagaagatg caaggagtaa
    11521 ccgcaggaac gactagagta cttaatttaa acagatctcc aaagggattg tgacaaaagt
    11581 cttgtcacag tccctttttc cgaataaacg gtgttcaatc agctgaccct tggtattagc
    11641 tcagcaaacg tcaaaatatg aggaactatt ttgacgtttg tttctctaat actcaggtca
    11701 aaacgctgat cttacgacct cttttcctta aacggtgttc tcctgccaac tcctcggtca
    11761 caagtcacaa tatcatcaaa catgagaagc agttttttga aattgctcct tgtgactcag
    11821 agttaaacgg caggctcaca acctctttct taaacggtgt tcaaaagctt gcatctgcgg
    11881 taatacgccc aatcaaacga aaaatatgag aagctatttt tgtttggctg ttcttattac
    11941 ttgatgcagg acagcttttt cacaacctct gattcacggt gttccaaaag tagcttcttc
    12001 gaaaaataag tcgaaatttc acaaaaattt gagaagcaat tttcgtacat tccttcttat
    12061 ttcttgaagc tgaccacttc tgttacaacc tcttttttaa taaccattct aaaaagataa
    12121 agttcgtttt ttaagcgttt ttataaaata aaaataaaaa tcattcgatt ttatttgaaa
    12181 tatgtatcta ttattgatac aatggttcag gattaaataa tatagaacga ggtgttcaca
    12241 tgtcatctgt agtagtagta ggtacgcaat ggggcgatga agggaaagga aaaatcacag
    12301 actttctcag tgaaaatgct gaagtgattg cacggtacca aggtggcgac aatgcagggc
    12361 acacaattaa gtttaacggt gtgacttata aactgcattt gattccttct gggatttttt
    12421 ataaagacaa gatcagtgtg atcggaaacg gcgttgtagt caatcctaaa tcattggtta
    12481 aagaattagc ttatttacat gaaaaaggtg tagaaacaag taatttgcgt atttctgacc
    12541 gcgcgcacgt aatcttgcct tatcatatca aattggacca attacaagaa gatgctaagg
    12601 gcgaaaataa gattggtaca acgattaaag gaatcggacc tgcctatatg gataaagcag
    12661 ctcgtgtagg tatccgtatt gcagacttat tagataaaga aatttttgaa gaacgtcttc
    12721 gtttgaatct agatgacaaa aaccgtcaat ttgtaaaaat gtttgattca gaaccacttg
    12781 attttgacga tatttttgaa gaatattatg aatacggaca acaaatcaaa caatacgtca
    12841 cagatacttc cgttatcttg aatgatgctt tggatgcagg caaacgcgtg ttgtttgaag
    12901 gcgcacaagg tgtaatgctg gatatcgacc agggaactta tccttttgtt acttcttcta
    12961 acccagtagc cggtggggta acaatcggaa gcggtgtagg gccttcaaaa atcaataaag
    13021 ttgtcggcgt ctgcaaagcc tatacgtcac gtgtcggtga tggaccattt ccaactgaat
    13081 tatttgatga aacaggagaa caaatccgcg aagtaggacg agaatacggt acgacaactg
    13141 gtcgtccgcg tcgtgtaggc tggtttgatt ctgtagttat gcgccattct aaacgagttt
    13201 caggtattac caacctatct ttaaactcga tcgatgtatt aagtggattg gaaacagtaa
    13261 aaatttgtac ggcttatgaa ttagatggcg aactaatcta ccactatcca gcaagcttga
    13321 aagagttgaa ccgctgcaaa ccaatctatg aagaattgcc aggctggtca gaagacatta
    13381 caggatgcaa aacacttgca gaactgccag aaaacgcacg taactatgta cgtcgtatct
    13441 cagagcttgt tggtgtacgt atctcaacat tttctgtcgg acctgataga acacaaacaa
    13501 acatcttaga aagcgtctgg gcgcaaatct aaggataaaa acgacgactg aatcaggacg
    13561 ttcttaccag agcgagtcga agtgtttatc tatacgataa taataacttg aagaggtagt
    13621 gaaagagacg tttagcctta ttgccgatag gctgtctctt gaacactgtt tattcagaat
    13681 aagggactgt gacaaaaacc gtgtcacagt ccctttttcc gaa
//
LOCUS       DADGHT010000079        13696 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.080, whole genome shotgun sequence.
ACCESSION   DADGHT010000079 DADGHT010000000
VERSION     DADGHT010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.080"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            496..1098
                     /locus_tag="JX887_002093"
     CDS             496..1098
                     /locus_tag="JX887_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1258068.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1114..1791
                     /locus_tag="JX887_002094"
                     /pseudo
     CDS             1114..1791
                     /locus_tag="JX887_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2303..2599
                     /locus_tag="JX887_002095"
     CDS             2303..2599
                     /locus_tag="JX887_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HAX1258069.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            2600..3016
                     /locus_tag="JX887_002096"
     CDS             2600..3016
                     /locus_tag="JX887_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAX1258070.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3036..4580
                     /locus_tag="JX887_002097"
     CDS             3036..4580
                     /locus_tag="JX887_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1258071.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            4723..4947
                     /locus_tag="JX887_002098"
     CDS             4723..4947
                     /locus_tag="JX887_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1258072.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            4962..5831
                     /locus_tag="JX887_002099"
     CDS             4962..5831
                     /locus_tag="JX887_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAX1258073.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5812..6546
                     /locus_tag="JX887_002100"
     CDS             5812..6546
                     /locus_tag="JX887_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1258074.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            6579..7487
                     /locus_tag="JX887_002101"
     CDS             6579..7487
                     /locus_tag="JX887_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAX1258075.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            7484..8026
                     /gene="sat4"
                     /locus_tag="JX887_002102"
     CDS             7484..8026
                     /gene="sat4"
                     /locus_tag="JX887_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAX1258076.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            8119..8913
                     /locus_tag="JX887_002103"
                     /note="aph(3')-IIIa"
     CDS             8119..8913
                     /locus_tag="JX887_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAX1258077.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(9021..9209)
                     /locus_tag="JX887_002104"
                     /pseudo
     CDS             complement(9021..9209)
                     /locus_tag="JX887_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9189..9761
                     /locus_tag="JX887_002105"
     CDS             9189..9761
                     /locus_tag="JX887_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1258078.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
     gene            10101..10955
                     /locus_tag="JX887_002106"
     CDS             10101..10955
                     /locus_tag="JX887_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAX1258079.1"
                     /translation="MEKEKLKILEELRRILNNKNEAIIILNNYFKGGVGKSKLSTMFA
                     YLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKNGNLASSIIHLTDNL
                     DLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIIIDTVPTPSVYTNNAI
                     VASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFVPYLVDTDSATIKSN
                     LEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVLSMYENVFFEMIERI
                     IQLENEKE"
     gene            11054..11263
                     /locus_tag="JX887_002107"
     CDS             11054..11263
                     /locus_tag="JX887_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAX1258080.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            11280..11552
                     /locus_tag="JX887_002108"
     CDS             11280..11552
                     /locus_tag="JX887_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAX1258081.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            11554..12417
                     /locus_tag="JX887_002109"
     CDS             11554..12417
                     /locus_tag="JX887_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAX1258082.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(12680..13417)
                     /gene="erm(B)"
                     /locus_tag="JX887_002110"
     CDS             complement(12680..13417)
                     /gene="erm(B)"
                     /locus_tag="JX887_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAX1258083.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(13542..13625)
                     /locus_tag="JX887_002111"
     CDS             complement(13542..13625)
                     /locus_tag="JX887_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAX1258084.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
BASE COUNT         4853 a         2128 c         2848 g         3867 t
ORIGIN      
        1 tatgatacgt gtttgttttt ctgtgctgtt tagtgaatga ttagcagaaa tatagagagt
       61 aagattttaa ttaattatta gggggagaag gagagagtag cccgaaaact tttagttggc
      121 ttggactgaa cgaagtgagg gaaaggctac taaaacgtcg aggggcagtg agagcgaagc
      181 gaacacttga tcttttaagt tgctatcttt ttaaggtcaa tagagtatac ttatttgtcc
      241 taatatggtt ttagcagtat aattgacttg gtgaataggt catttaagtt gggcataata
      301 ggaggagtaa aatgaaaaaa tttatttatc gagttttaga aaatgacgaa gtggtggcta
      361 tttttaatga gcaacaatat gcgcaagatt ttatcgctta cgaaaagaca atttctgata
      421 agcaatttga aattgaaaaa gtagatatag ctgattggtt attgcaaccg agagaatttt
      481 agaggttggt tgaaaatggc taaaattggt tatgcacgtg tcagtagcaa agaacagaac
      541 ttagatagac aactgaaagc gttagagggc gtttctaagg tcttttcaga caaattaagc
      601 ggtcaatcgg tcgaacgccc acaattacaa gctatgctta actatattcg tgaaggggat
      661 atagttgttg ttactgaatt agatcgatta ggacgaaata ataaagaatt aacagaattg
      721 atgaatcaaa ttcaaattaa gggggcaacc ctggaagtct taaatttacc ctcaatgaat
      781 ggtattgaag atgaaaattt aagacggctg attaataatt tagtgattga attgtataag
      841 taccaagcgg aatctgaacg caaacgaatt aaagaacgcc aagcccaagg aattgaaatt
      901 gctaagaaaa aaggaaaatt caaagggcga caacctaaat tcaaagaaaa tgatccacgt
      961 ttacaacacg ctttcgattt atttttgaat ggttgttccg ataaagaagt tgaagaacaa
     1021 actggaatta atcgccgaac gtttagaagg tatcgatcaa gatacaacgt gacagtagat
     1081 caaagaaaaa aacaatgaaa agagggatag ttaatgagta cggttatttt agctgaaaaa
     1141 ccaagccagg cattagccta cgcaagtgct ttaaaacaaa gcaccaaaaa agacggttat
     1201 tttgagatca aagacccact atttacagat gaaacgttta tcacctttgg ttttgggcat
     1261 ttagtcgaat tagcagaacc aggtcattat aacgaaaagt ggcagaactg gaaacttgaa
     1321 tctttgccga tttttcctga tcgatacgat tttgaagttg caaaagataa gggaaagcag
     1381 tttaaaattg ttgctgaact tctcaaaaag gcaaatacaa ttattgtcgc aacagatagc
     1441 gacagagaag gtgaaaatat cgcctggtcg attatccata aagcaaatgc cttttctaaa
     1501 gataaaacgt ataaaagatt atggatcaat agcttagaaa aagatgtgat ccgaagcggt
     1561 tttcaaaatt tgcaaccagg aatgaattac tatccctttt atcaagaagc gcaaacacgc
     1621 caaattgccg attggttgat cggcatgaac gcaagccctt tatatacctt gaatttacaa
     1681 caaaaaggcg tacaaggtac attttcatta ggacgtgtac aaacaccgac tttatatctc
     1741 atttatcaac gccaggaagc aatagaaaac tttaaaaaag aacctttttt cctgaataat
     1801 tcatagtttt actaatagtc tttcctaaca ttgatttaat agtctttaaa gtattctgct
     1861 tcatcaccca ttaggtgatg aaaaaagaac ccctttctga tttagcggac aaatactttg
     1921 acctaatctc agaagatata aaagaaaaaa taataaaata tccgatttat actttgtata
     1981 aagaactaaa gtagttagca aatcatttac agcaaatcac tatgttccac ataccatttt
     2041 acatacttac cttatccacg acacatgttg agatagtatc gaagataaag aaagttgctc
     2101 catgttgttt ttgcgagatg gggaaatcaa agccacattg acaaccatga tgaataagct
     2161 tgctttcagt cataagctaa tcctagaacc acttttcaag tcagttagcc aaatcgatga
     2221 agaaagcgac cgtgaaagaa tggacgctat tgataagcta atggagcaac tattggaaga
     2281 acgcaatacc cttattgcac tgatgtccaa aggtttccta gaacctgctc tttttaatca
     2341 ggaacgaaat gttttagata gtgagattaa aaatcttact accgaaaaaa caaacctggt
     2401 aacgaactct gcgagtgggg ttttgcgagc aaacgagata aaggacctca ttaattatgt
     2461 gtcagcagat aattttaatg gtgactacac ggaagaacta tttgaagaat ttgtagtgaa
     2521 catcattgta aattccaggg atgagctgac attcaatttg aaatgcggtc tttccctgaa
     2581 agaaaaggtg gtgagataaa tggcatatat tccatatgga tacaaaattc aagatggagt
     2641 ggttactgtc gatgaaaagg cagcaggtca agtaaaggta ttctttgaga aatacatatc
     2701 aggactatcc cttacagtgg ctggcgaaca ggcaggtatt gaaaagacac attctgtgat
     2761 ggggcgcatt ttgaaaaacg tcaactacct tggaaatgat acgtatccag caattattga
     2821 taaagagata tttgataaag ctgaagaagt tagagataaa cgtgcaaagg atttaggacg
     2881 agtggtagag cttgccgctt tcacctctcc ccctcccaaa gaacgattca aaatgaaaaa
     2941 ggcagataat aagatgccag tggatccttt tgaacgagca gaatacttat acagtctgat
     3001 agaaagcgag gaataaagtg acagagaaaa atataatggt tattcctgct cgtaaaagag
     3061 taggaagtac agccgcaaaa gaaaagataa agaaacttcg tgttgctgcc tattgccgtg
     3121 tttctacaga aacagaagaa caaaattcta gctatgaggt tcaggtctca cactatacag
     3181 agtttataaa gaaaaataat gaatgggagt ttgctggcat ctttgcagat gatggtatct
     3241 ctggtacgaa cactaaaaag cgtgacgaat ttaatcgcat gattgcagag tgtatggacg
     3301 gtaacatcga catggttatt acaaaatcca tcagccgatt tgcgcgtaac accctagact
     3361 gccttcaata cattagacag ctcaaggata agaacatatc agtttatttt gagaaagaga
     3421 acatcaacac cacggatgcc aaaggtgagg ttttgctgac tattatggca tctttggcac
     3481 agcaggaaag ccagagcctt tcacaaaacg ttaagcttgg gctacagtac cgataccaac
     3541 aaggaaaggt gcaggtcaac cataagcgat ttatgggcta cacgaaagat gaagatggaa
     3601 atttaactat tgtccccgaa gaagctgaga ttatcaaacg catctaccga gaataccttg
     3661 agggtcagag tctagtgggc attggtcgag cccttgaaaa ggatggtatt ttaacagcag
     3721 cgggaaaacc aagatggcga ccagaatcag ttaagaagat acttcaaaac gaaaaataca
     3781 tcggagatgc ccttctgcaa aagactgtca cagtagattt tctgaccaag aaacgagtga
     3841 aaaatgaagg gcatgttccc caatattatg ttgaaaatag ccatgaagcg attattccta
     3901 aagagttatt tttgcaggcg caagaagaaa ttcatcggag aagcaatatc tacacaggag
     3961 aaggcaagaa caaaagaatt tacagtagca agtacgcttt aagtgccatc accttctgtg
     4021 gagattgtgg cgatatttat agacgggtct attggaatat ccacggaaga aaagaatttg
     4081 tctggcgatg cgtgactaga atcgagcaag gtcctgaagt ttgtaagaac cgaaccgtaa
     4141 aagaagatga actttatggt gcagtaatga ctgcgattaa taagctactt gcaggtggga
     4201 acaatatgat aaagacactg gaagagaata ttcatgctgt gattggcgaa accacagaat
     4261 accaaatttc agagattaac aactcactag aggaaaaaca aaaagaacta atcaagctgg
     4321 cgaacaaggg tcaagactat gaccacttag cagatgagat tgatgagctg agagacaagc
     4381 gacagatcct tttagtagaa gatgcctccc tcagtggcga gaacgagcga atcaatgagc
     4441 tgattgaatt tatccgcaag aacaaattcc gcaccttaga atatgatgat aagcttgtaa
     4501 ggaagataat ccagagcgtt acagtctatg aaggccactt cgtcatagcc ttcaaatctg
     4561 gcatcgaaat ggaaatatga aaaccagaag taaatagccc atgactctac agtagagttg
     4621 tgggttttct tttgcttgct gattataata atattttaat aactattgtg tttatcaacc
     4681 aaatggttta taatattctt agcgtaaact tggaggtgct gtatgactac ggcagaaatg
     4741 attaaagaac tgtgtgagca aatgaatata agtgtttccg aacttgctag acgtattggc
     4801 cagactccac agaatttcaa taaaaaatta caacgagaaa cagtaacctt ggatgagttg
     4861 aaggccattg ctgatgtgct aggtgtcaag tttgtgcagg catttatttt accagatgga
     4921 gaagaaataa aaatatctaa cgaataaagg aggatgttta tatggtaggt aatgttattc
     4981 aaatagtaac agagaaatta tcatctttgc cttttataga aggcatcgta ttagggggct
     5041 cacgtgcaag aggcacccat acagaaaatt ctgatataga tatcggaatc tattacaatt
     5101 cagactcatt tgacctgaca gcgattaatc aaattgctac agagttggat gatgagaata
     5161 gaaacaacct tgttgtacct cccggagcgt ggggtgattg ggttaatggc ggtggatggt
     5221 tagttataaa cgggtgtcat gttgacttga tattacgtga tataaaacgg gtggaacaaa
     5281 taatcaaaga tacggagcaa ggaattgtta ctgccaatta tcagaccggg catccccatg
     5341 gttatataag tgctatgtat cgtggagaat tagcgattag taaaatacta tatgctaaga
     5401 acgaaagctt atgcgaatta aaaaagcagg cagaaattta ccctactgct ctaaagaaaa
     5461 gcttgatgaa cttttttata tttgaagctg aattctcttt aatgtttgta aaagcaaatg
     5521 cgggggcaga ggataaatat tatattgcag gccatgtttt tcgtattatt tcatgcttaa
     5581 atcaagtact atttgcatgt aataatgctt attgcattaa cgaaaagaaa gctataaaac
     5641 tgcttgaaac ttttgaatat aaacctgaaa aatatgccga aagagttaat catatttttg
     5701 aagtactcgg tctttctctt tttgaatgct acgacatgac cgagaaactt tataaagaag
     5761 tgaatgaaat tgtatcggag ataaataact ttttaaacga ggagagttca gatgaaagaa
     5821 aacaaatatg atgataatat attttttcaa aaatacagtc aaatgagtcg ctcgcagaaa
     5881 ggactggctg gtgcgggaga atgggagact ttgaaaaaga tgctacctga ttttaagggt
     5941 aagcgtgtgc ttgatttagg atgcggctat ggatggcact gtatatatgc gatggaaaac
     6001 ggtgcttcct ctgtagtagg tgttgatatt tctcataaaa tgctcgaagt agcaaaagga
     6061 aaaacccatt ttccacagat tgaatatgaa tgctgtgcca tagaagatgt ggatttccca
     6121 gaggagagct ttgatgtaat actaagttcg cttgcgtttc attatgtagc agactatgag
     6181 aatttaataa aaaagatata taggatgctg aaggctggtg gcaatttagt ttttacagtt
     6241 gaacatcctg tttttactgc tcatggaaca caagactggt attataacga aaaaggagaa
     6301 atactgcatt tcccggtgga caattattat tatgagggca aacggacagc tatgtttttg
     6361 gaagaaaagg ttacaaaata tcatagaaca ctgaccacat atctaaatac actgctttca
     6421 aatagtttta taataaatca gattgtggag ccacagccgc cagagaacat gatggatatt
     6481 ccggggatgg cggatgaaat gcgacgccca atgatgctga ttgtatcggc aaaaaagaag
     6541 atgtaataat atagaaaaaa taaacgagga gtatgtaaat gagatcagaa aaagaaatga
     6601 tggatttagt actttcttta gcagaacagg atgaacgtat tcgaattgtg acccttgagg
     6661 ggtcacgcgc aaatattaat atacctaaag atgaatttca ggattatgat attacatatt
     6721 ttgtaagtga tatagaaccg tttatatcta atgatgactg gcttaatcaa tttgggaata
     6781 taataatgat gcaaaagccg gaggatatgg aattattccc acctgaagaa aagggatttt
     6841 cctatcttat gctatttgat gattacaata aaattgatct taccttattg cccttggaag
     6901 agttagataa ttacctaaag ggcgataaat taataaaggt tctaattgat aaagattgta
     6961 gaattaaaag ggacatagtt ccgactgata tagattatca tgtaagaaag ccaagcgcaa
     7021 gggagtatga tgattgctgc aatgaatttt ggaatgtaac accttatgtt attaaaggat
     7081 tgtgccgtaa ggaaatttta tttgctattg atcattttaa tcagattgtt cgccatgagc
     7141 tgctgagaat gatatcatgg aaggtcggca tcgaaacagg ctttaaatta agtgtaggca
     7201 agaactataa gtttattgaa aggtatatat ccgaggattt gtgggagaaa cttttgtcca
     7261 cctaccggat ggattcctat gaaaacatat gggaagcatt atttctatgc catcaattgt
     7321 tcagggcggt atccggtgag gtggcggaaa ggcttcatta tgcctatccg gagtatgata
     7381 ggaatataac aaaatatacc agggacatgt ataaaaaata cactggtaaa accggctgcc
     7441 tggatagcac atatgccgct gatatagaag agaggcggga acagtgatta cagaaatgaa
     7501 agcagggcac ctgaaagata tcgataaacc cagcgaacca tttgaggtga taggtaagat
     7561 tataccgagg tatgaaaacg agaattggac ctttacagaa ttactctatg aagcgccata
     7621 tttaaaaagc taccaagacg aagaggatga agaggatgag gaggcagatt gccttgaata
     7681 tattgacaat actgataaga taatatatct ttactaccaa gacgataaat gcgtcggaaa
     7741 agttaaactg cgaaaaaatt ggaaccggta cgcttatata gaagatatcg ccgtatgtaa
     7801 ggatttcagg gggcaaggca taggcagcgc gcttatcaat atatctatag aatgggcaaa
     7861 gcataaaaac ttgcatggac taatgcttga aacccaggac aataacctta tagcttgtaa
     7921 attctatcat aattgtggtt tcaaaatcgg ctccgtcgat actatgttat acgccaactt
     7981 tgaaaacaac tttgaaaaag ctgttttctg gtatttaagg ttttagaatg caaggaacag
     8041 tgaattggag ttcgtcttgt tataattagc ttcttggggt atctttaaat actgtagaaa
     8101 agaggaagga aataataaat ggctaaaatg agaatatcac cggaattgaa aaaactgatc
     8161 gaaaaatacc gctgcgtaaa agatacggaa ggaatgtctc ctgctaaggt atataagctg
     8221 gtgggagaaa atgaaaacct atatttaaaa atgacggaca gccggtataa agggaccacc
     8281 tatgatgtgg aacgggaaaa ggacatgatg ctatggctgg aaggaaagct gcctgttcca
     8341 aaggtcctgc actttgaacg gcatgatggc tggagcaatc tgctcatgag tgaggccgat
     8401 ggcgtccttt gctcggaaga gtatgaagat gaacaaagcc ctgaaaagat tatcgagctg
     8461 tatgcggagt gcatcaggct ctttcactcc atcgacatat cggattgtcc ctatacgaat
     8521 agcttagaca gccgcttagc cgaattggat tacttactga ataacgatct ggccgatgtg
     8581 gattgcgaaa actgggaaga agacactcca tttaaagatc cgcgcgagct gtatgatttt
     8641 ttaaagacgg aaaagcccga agaggaactt gtcttttccc acggcgacct gggagacagc
     8701 aacatctttg tgaaagatgg caaagtaagt ggctttattg atcttgggag aagcggcagg
     8761 gcggacaagt ggtatgacat tgccttctgc gtccggtcga tcagggagga tatcggggaa
     8821 gaacagtatg tcgagctatt ttttgactta ctggggatca agcctgattg ggagaaaata
     8881 aaatattata ttttactgga tgaattgttt tagtacctag atttagatgt ctaaaaagct
     8941 ttaactacaa gctttttaga catctaatct tttctgaagt acatccgcaa ctgtccatac
     9001 tctgatgttt tatatctttt ctaaaagttc gctagataga gttctatatt agagatgtaa
     9061 agagttttgg tgaagaggtt tgtgagtatg gcttttataa ccagggtgca atgagaagca
     9121 ctaacagcag ctagcttaag aacgcatagg atatactttt tatggaagtc acagaggagg
     9181 aataaaattt gaacaggatt aacagagtaa cctctattct tattcagctg caatcaaaaa
     9241 aaataattcc tgccaaagaa attgcacagc gatttaatat aagcttaagg acagtttaca
     9301 gagatatccg gacacttgaa gaagccggaa taccaattgg atctgaggcc ggaaaaggat
     9361 attttcttgt agagggcttc ctacttccgc cggtaatgtt tacagcggcg gaagtgggtg
     9421 cattgattac agcagggaaa tttttaaatt gccatggaga tgaatcattt ataaaggatt
     9481 ttgattcagc tatgtataaa atcaaatcta ttttgaagca tggtgaaaaa aactatgcac
     9541 aggagttgga gaacagtatt aacgtgtaca gcacatctgg acagaaaaat acattggcgg
     9601 ataacgttat tgcagcaatt cagactgcaa tctgcaataa aagggtaata tcaattcaat
     9661 atcctgcatc aggagggcaa gaaccggaaa gcagaatgat agagcctata tcactggggt
     9721 tttatgaaca gaactggtac ttaatcggtt ttgcaggcta agaaatgaat ataggaattt
     9781 tcgtgtggat cggattaaaa gcatttgcat agaagaagag ctctgtcaaa gccatgatgg
     9841 ctctttggaa caaatattaa aacaaatgct ttcatataaa aaactatatg ccctacaatg
     9901 ccgttgtaaa aattggggaa aagggatata ttgattttat atctttctca aaataaatat
     9961 aaaagccctt taaagagggc ttttatatat taatcacaaa tcacttatca caaatcacaa
    10021 gtgattaatc acaaatcact tgtgatttgt gattcttaat gatacaatat tactatacaa
    10081 aaaaagaatg gggcgtagtt atggagaagg aaaaactaaa aatacttgaa gaattaagac
    10141 gtattttaaa caataaaaat gaagcaatta ttatcttgaa taattacttt aaaggtggtg
    10201 ttggaaagtc caaattatcg actatgtttg cttacttgac agacaaattg aatttaaaag
    10261 ttttaatgat cgataaggac ttacaggcaa cattgacaaa agacttagca aaaacttttg
    10321 aggtagaatt gccacgtgtc aatttttatg aaggcttgaa aaatggaaac ttggcttctt
    10381 ctattattca tttgactgat aatttagact tgatccctgg cacgtttgat ttgatgttac
    10441 tgccaaaatt aactcgctca tggacgtttg aaaatgaaag tagattgctt gctactcttt
    10501 tagcaccttt aaaaagtgac tatgatctta ttattattga tactgtacca acgccaagcg
    10561 tttatacaaa taatgcaatc gtggcgagtg attacgttat gatcccttta caagcagaag
    10621 aagaaagtac aaacaacatt caaaactata tttcctattt gattgatttg caagaacagt
    10681 ttaaccctgg actagatatg attggttttg ttccttattt agttgatacg gacagcgcaa
    10741 cgataaaatc aaacctggaa gaactgtaca aagaacataa agaggataat ttggttttcc
    10801 gaaatattat caagcgaagt aataaagtaa gtacttggtc taaaaatggc attacagaac
    10861 acaaaggcta tgacaaaaaa gttttgtcta tgtatgagaa cgtatttttt gaaatgattg
    10921 agcgaatcat tcaattagaa aatgaaaaag aatagaatca caaatcacaa gtgattaatc
    10981 acaaatcact tgtgatttgt gataggtgat gataaaataa atagtaagaa gaaatagaaa
    11041 gaagtgagcg atcgtgggaa atttaggcgc acagaaagca aaacgaaatg atacgccaat
    11101 cagcgcaaaa aaagatataa tgggggataa gacggttcgt gttcgtgccg acttgcacca
    11161 tatcataaaa atcgaaacag caaagaatgg cggaaacgta aaagaagtta tggatcaagc
    11221 cttagaagaa tatatacgga aatatttacc tgacaaactt taaaaggagt gaaaatgaaa
    11281 tggcagttac gtatgaaaaa acatttgaaa ttgaaatcat taatgagtta tcggcaagtg
    11341 tttataatcg ggtattaaat tatgttttga atcatgaact agatactaaa aatactcgtt
    11401 tactagaagt gaatctttta aatcaattag aagtggcaca agaagttgat ttatttcaac
    11461 aaccatttga agaattacaa gctattcatg agtattggcg gtcaatgaat caatattcaa
    11521 aacaaatttt gaataaagag aaagtggctt aacatggcga atattactga cttcaccgaa
    11581 aagcaatttg aagatcgttt agaaaagaat gttgaacgac taactaaaaa tagactagcg
    11641 gttgaatcgc caaccgcttt tttacttggt gggcaaccag ggtcagggaa aaccagtttg
    11701 cgatcagcaa tttttgaaga aacacaaggg aatgttattg tcattgataa tgataccttt
    11761 aaacaacagc acccaaattt tgacgaatta gtgaaactct atgaaaaaga cgtagtaaaa
    11821 cacgttaccc cttattcgaa tcgcatgaca gaagcactta ttagccgttt aagcgatcaa
    11881 ggctataatt tagtgattga aggaacagga cgaacaacag acgttcccat tcaaacagcc
    11941 acaatgcttc aatctaaagg ttatgaaaca aaaatatacg tcatggcagt accgaaaatt
    12001 gaatcatact taggaacgat tgaacgatat gaaaccatgt atgcagatga tccaatgaca
    12061 gctagggcaa caccaaaaca agcgcatgat attgttgtca aaaacttacc gaccaattta
    12121 gaaacccttc ataaaacggg cttatttagc gatataaggc tttacaatag agaaggagtg
    12181 aaactctatt caagcttaga aacgccttcc attagtccga aagagacctt agaaagagaa
    12241 ttaaatcgta aagtatcagg gaaagaaatt caaccgactt tggagagaat agagcaaaaa
    12301 atggttcaaa atcaacacca agaaacccct gaatttaaag caattcaaca aaaaatggaa
    12361 agcttgcagc tacctacacc accaataccc aaaacaccta aacttccagg tatttaaacc
    12421 ttaaaaaagg aaaagagtag ttaccaaaaa acggtaacta ctcttttttt ataaaaacat
    12481 ttcctcatgt tggggtcccg agcgcctacg aggaatttgt atcgataaga aatagattta
    12541 aaaatttcgc tgtttttttc taatttcatt ttgaggtgaa ttaattggta gttattagag
    12601 gtgccctata cctaataatt tatctacatt ccctttagta acgtgtaact ttccaaattt
    12661 acaaaagcga ctcatagaat tatttcctcc cgttaaataa tagataacta ttaaaaatag
    12721 acaatacttg ctcataagta acggtactta aattgtttac tttggcgtgt ttcattgctt
    12781 gatgaaactg atttttagta aacagttgac gatattctcg attgacccat tttgaaacaa
    12841 agtacgtata tagcttccaa tatttatctg gaacatctgt ggtatggcgg gtaagtttta
    12901 ttaagacact gtttactttt ggtttaggat gaaagcattc cgctggcagc ttaagcaatt
    12961 gctgaatcga gacttgagtg tgcaagagca accctagtgt tcggtgaata tccaaggtac
    13021 gcttgtagaa tccttcttca acaatcagat agatgtcaga cgcatggctt tcaaaaacca
    13081 cttttttaat aatttgtgtg cttaaatggt aaggaatatt cccaacaatt ttatacctct
    13141 gtttgttagg gaattgaaac tgtagaatat cttggtgaat taaagtgaca cgagtgttca
    13201 gttttaattt ttctgacgat aagttgaata gatgactgtc taattcaata gacgttacct
    13261 gtttacttat tttagccagt ttcgtcgtta aatgcccttt acctgttcca atttcgtaaa
    13321 cggtatcggt ttcttttaaa ttcaattgtt ttattatttg gttgagtact ttttcactcg
    13381 ttaaaaagtt ttgagaatat tttatatttt tgttcatgta atcactcctg aagtgattac
    13441 atctataaat aaatacagaa gttaaacgat ttgtttgtaa ttttagttat ctgtttaaaa
    13501 agtcataaga ttagtcactg gtaggaatta atctaacgta tttatttatc tgcgtaatca
    13561 ctgtttttag tctgtttcaa aacggtagat gttttatcta cattacgcat ttggaatacc
    13621 aacatgacga atccctcctt cttaattaca aatttttagc atctaattta acttcaattc
    13681 ctattataca aaattt
//
LOCUS       DADGHT010000080        13604 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.081, whole genome shotgun sequence.
ACCESSION   DADGHT010000080 DADGHT010000000
VERSION     DADGHT010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.081"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..266
                     /locus_tag="JX887_002112"
     CDS             <1..266
                     /locus_tag="JX887_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HAX1258085.1"
                     /translation="LLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITDDAADQL
                     NEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            263..1021
                     /locus_tag="JX887_002113"
     CDS             263..1021
                     /locus_tag="JX887_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAX1258086.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(1107..1847)
                     /locus_tag="JX887_002114"
     CDS             complement(1107..1847)
                     /locus_tag="JX887_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1258087.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            1908..3161
                     /locus_tag="JX887_002115"
     CDS             1908..3161
                     /locus_tag="JX887_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAX1258088.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            3462..3710
                     /locus_tag="JX887_002116"
                     /pseudo
     CDS             3462..3710
                     /locus_tag="JX887_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            3832..4158
                     /locus_tag="JX887_002117"
     CDS             3832..4158
                     /locus_tag="JX887_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAX1258089.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            4226..4939
                     /locus_tag="JX887_002118"
     CDS             4226..4939
                     /locus_tag="JX887_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAX1258090.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            5249..6101
                     /locus_tag="JX887_002119"
                     /pseudo
     CDS             5249..6101
                     /locus_tag="JX887_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            6222..8087
                     /locus_tag="JX887_002120"
     CDS             6222..8087
                     /locus_tag="JX887_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1258091.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            8135..9544
                     /locus_tag="JX887_002121"
     CDS             8135..9544
                     /locus_tag="JX887_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAX1258092.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            9652..10353
                     /locus_tag="JX887_002122"
     CDS             9652..10353
                     /locus_tag="JX887_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1258093.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            10512..10991
                     /locus_tag="JX887_002123"
                     /pseudo
     CDS             10512..10991
                     /locus_tag="JX887_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            11839..12414
                     /locus_tag="JX887_002124"
     CDS             11839..12414
                     /locus_tag="JX887_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAX1258094.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            12414..12854
                     /locus_tag="JX887_002125"
     CDS             12414..12854
                     /locus_tag="JX887_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAX1258095.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            12870..13571
                     /locus_tag="JX887_002126"
     CDS             12870..13571
                     /locus_tag="JX887_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAX1258096.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         4557 a         2238 c         2878 g         3931 t
ORIGIN      
        1 atttacttgt cccattagaa ggaaaaaaat tagctccggg acattatcaa gcggttgtga
       61 agggtgcttg gaaagaaaaa cgctggaatc tccataccga ttttgaaata actgatgatg
      121 cagcggacca attgaatgaa aaggatattg atttaaaaaa tcagccagaa acatttgact
      181 ggcgatggct gatacttgtt ggagtcattc ttattggctt atttgctgga ttatttattt
      241 taaaagaaag aaggaaaaag aaatgaaaaa aacaattgca ttaagtaccg ttctagctgg
      301 aagtctatta ttatgtacac aaagtgtttt tgctgagaat aagagctcag ccactacaga
      361 aggaacgatt tctgtaacaa aaccagatgc cgcaaatcct gaagacgttg ttccagttcc
      421 tcctgttgat ccaaatgatc ccgatacgcc gtttacacct aacgaaccaa atcagggaac
      481 atccggatta ctgacgattg accaagctcc agatcttgat tttggaacaa tcaagttagg
      541 tacagcaaaa acagtatatg ctgcattaca aaacggaacg gacagtacag ggacagcaac
      601 acaagtacag aatttcgtac aagtaacgga taaaagcgga atttatgccg gttggaaact
      661 atcagtcaaa cgaacagaat ttattggtac aacatctgat acgaataaac taactggttc
      721 aaaggtgaaa ttcaaaaacg ccgtgattcg aaatagcgca actaatagca gtggaacgcc
      781 atctactatt tctggtactg gcgctgaagg aattgagatc ccagcagatc aggcagtaga
      841 tctagtaact gcaggagcaa atgaagggat tggcacatgg atttattcat taggagagaa
      901 tgtggaacaa gggagacaat cagtggaatt atttgttcct gtatccaatt atgccgtaga
      961 caactacgtt tcaacattca catggtcgtt aacagatgct cctacagaag ggaaagcgta
     1021 aaatcaaatc aatgacttca gggagtggag ccgattcaag gccaactccc tgaaatctgc
     1081 tatgcttacg tctcagctct tattcatcaa ctcgaagcag ttttttggaa gtcatggaaa
     1141 cgttcctttg tcttttcaaa gatctttcga ccaacgagta aggagtcacc attgaaaaat
     1201 tctaacacat aatgagcaga atcaattttc tgcaattgcg ataagttgat acagtaagat
     1261 tttaatagta aaaagtaagc atacttttcc aactctgtct tcaattgttt taaagaagta
     1321 ttcactaatt tatcttctgt agttgttttg accataactt ggtttttcaa acctttgata
     1381 ctttcaatat ataaaatttc ccgaggatac aggacgagac ttccaccttt ttgatcaata
     1441 aagattttat cgacatttac gatttgctgt tctttccaat tgatctgttc tagcacttga
     1501 cgaatttgtt cagataaatt cctgtctttt ctgatatatc caatcggaag gattttccga
     1561 ttgatgatct ctactgcaaa attcgtataa gcggtgaaaa aaacaatatt actatgtgca
     1621 ttttttttac gtatttgttc ggcgacatca atacctgtga gtgattgctt caagtcgata
     1681 tcgataaaga aaacatcgtg attatcaata gtacccaact ggatcaactg attgatttga
     1741 gagatagaag tgagctgcac gatattctcg atatgatgat tgaccaattc tttgatgatc
     1801 cattcgctgt gaaactggtt atcttctatg ataaaatact ttttcatatg caggctccta
     1861 ttaaaaaaat atgtgtacat tttgaaacaa aacaatggag gaataagatg gtcgcaacag
     1921 tgacacttta tttgaccttt actttgattt tagatttagg tatctattta ttcttttcga
     1981 aacaactgct agtaaaaaac agctttggtt ttatagcttt gatggtggtg acacttttat
     2041 ttcctatccc taaagtgagc tttccttacc tagttggctt attattgatg tttctttttt
     2101 attttactac gaaaaacctg tttatcagct gtttgatcag taatcttttt tttgctatca
     2161 ctggactcag cttttttctg gtttttgatc tgatggatta tttaggaaag agacatcttg
     2221 gaacagcaag tttttttgca ctacttatcg catttatttt ctatctatta gtaaaaagta
     2281 tagacaaaca gacgagattt ctcaacttgc tttttactta tccaactgaa cactattttg
     2341 gaggtatttg tattttatta agctggggcg tgatttactt ggtattggga agtgttcact
     2401 tccgctcatc taattatctg cttctatctc ttttgtcgat agtcatcagt tttttttctt
     2461 tgtttttttc cattatgttg atcagtttcc aagtaaaaga aagacaacat caggaatcgc
     2521 ttcaactgta tcaaataaat gaagaatatt accatcatct agaggaattc aaacatgatt
     2581 ataaaagtct actgttttca ttaaaaatta ctcttcagga aaataaaaaa gaaacgttgg
     2641 aatttttaga aatcttagaa gatcattctg cagctatttt tgaaaaaccg caaatacaac
     2701 agctaacaaa tattgtatcc ccagctgtca ggggtgtctt tttaaaattt ctagaaaaag
     2761 cagaatcgga gaaaatcccg atccaagtag ttattcctgt cgaagtgaaa acaatcccga
     2821 ttgatctggt tgtttttatt cgctgtttat ctatttttat ttctaacgca ttcgatcatc
     2881 gtgtagccga tcagagtccg attacgatca atctgctgga agaaaaagag ggattacgtt
     2941 ttagtatagc gaacaaggca aatccgacga atttgacgct atcggagatg gtcaaaagag
     3001 gaaaaacctc taaaaaaaat ggcgggttag gtctatacag tgcgaaaaaa atgttggatg
     3061 tttacgaaaa tgcagaacta aaaatcgaat tttcaaaaca gaatcactat ttttttgtag
     3121 aaatgtatct ggcatctaga aagagcaaat cagcctactg acttactgtc aaaggataag
     3181 cttgaggaaa gtctacacgg agatagagac aacaacacag catattcaaa agaaacagaa
     3241 gcgtgatgac cgttgtcacc cttctgtttc ttttgctatg tagttaaaca aagtagttga
     3301 cacttccgct acttagtatt agtacgaaag tatacttcat gatactaagt agataagaag
     3361 tgaaaagcgg aacccacgat cgtcaaaatg ctaactgctt tgcttacacc agataaaggg
     3421 aagagcaata tcgcttattt taggcgtgga gaagcaagaa aatccctacg atcacacaaa
     3481 aaatgctgac ccagcagtta agagagttag aacaagatgg cattgtccat cgaaaagtct
     3541 ataaccaagt cccgcctaaa gtagagtact cgctcaccga agaaggaaaa tcattaagag
     3601 agattctagt agcgatgtct gtttggggag aagaacgtat cgaaaaacaa aaagcctcag
     3661 gggaagaagt cacattactg catacacatg gtggctacct aaattactga tttctatgac
     3721 atttatttta aataaaagaa aacaggagtt tttttaaaag catcatctat tttttatgta
     3781 aaaaaatggt atgattaatc aagtaagaaa tgattggaag aaggcaagca aatgaatagc
     3841 atggaaaaag ttaaccagtt tagagatgaa cgtaattggc gacaatttca taacgaaaaa
     3901 gatttggcta tttctatttc tttggaagca tctgaattgt tagaactttt tcaatggaaa
     3961 acgccggaag aagtaaaaga aacacaatta gaacgaatca aagaagaact ggcggatgta
     4021 ttgatctatt catacatgat ggcagacaac cttcagctgg atctagatga gatcattgaa
     4081 gaaaaattga tcaaaaataa tttgaaatat cctgtagaaa aaagcgcagg tgtacgaaaa
     4141 aaatacacag agttttagaa atgtgtcatt cggctgttgg aaagagcaaa agaaaaacag
     4201 taaaatgagt ctggagggag agaaaatgaa aaaaaaagga aaagcaaaaa gatggctagt
     4261 caatatcctc ttgttcctct tgttattagt aggactagct ttgattttca atgaacagat
     4321 caaggattat cttgtcagag agacaggaga taaatatgct atagcgaatg taacaaaaga
     4381 agatctgaaa aagaataacg ataaagatgt cagttttgac tttgatgcgg tagaaccaat
     4441 gacgacagaa ggggtcatga ggtcgcagat gagaggaaca gatctaccag tgattgctag
     4501 tatcgcagtc ccttcagttt caatcaattt accgattttc aaaggcttgg ataatacgtc
     4561 actactttac ggagcaggaa cattatctcc agatcaagaa atgggaaaag gaaattatgc
     4621 cttagcaagc catcgtgcaa cgaaccctga attgttgttt acaccgctgg aaaatttaga
     4681 gatgggtgcc aagatctatt tgacagattt agaaaatgtg tatacataca aaacattttt
     4741 taaagaaaaa gttgctccta cagataccca attactgaat gaagtcgagg aaaaagaaat
     4801 tgtcacacta attacttgtg gcgacatgga cgccgtcacg cgactagttg tacaaggaga
     4861 actggaaagt gttacaccga taaaagatgc gacagatgat atgagatctg ctttcaatct
     4921 agagacaaaa acattttagg atactgggac ataagtcgtt acagattaaa aacagccaaa
     4981 ggatatgaat cgataaggaa aaaccaattt gctgaaaaaa agaggaacgc aaagaggtgc
     5041 atctctgatt tggttgtttt ctagatagac ttgtgttcca gtttttttat tttttatatg
     5101 aaaaggcttg cataaataaa aattcgatgg tatgatgatt ttgaataaga aatggattgt
     5161 tactgtacgg caggcaaaac cagaattcag ctaagaaaca gtaggcgaat tctaggtttt
     5221 tttatttttc ttgagagggc gaagcaaaat gaaaattgat aaaattttga ataacaatgt
     5281 cgtcatttcg aaaaatggat tcggggaaga agtcgtttgt atgggaaaag gactagcttt
     5341 tcaaaaaaaa gattggggac gagatttcgc cagaagcggt ccaaaaagaa tttattttaa
     5401 gagattcttt tgctaaaaac caattccagc agctgatggc tgatattccg gcagaggaga
     5461 tcgaatgggt caaacaagta gtcgaactgg ctgaagataa actaaaagtt gaattttcgc
     5521 ctaatattta tctgacattg accgatcatc ttcattatgc gatcacacga gcaaaagaaa
     5581 atatccaact gcctaatcca ttattatttg aaacaaaaaa attttatccg aaagaatatc
     5641 aagcagcgaa agaggctctt ttgttcgtga aacaaaagac gggtgtggaa ctttctgagg
     5701 atgaagccgg ttttattgcc tttcattttg tgaatagcca acaaggaaac gaagacatgc
     5761 aagtgacgat gaccgctacc acaatggtaa gagatatact gagtatcatc agtaaattct
     5821 tcggcatcgt gttcgatgaa gaatctttga attatcagcg tatcattact catctgcagt
     5881 tttttgccca gcgttatctc aaaggggaag gatctgacga gcaagatgaa tttctctacg
     5941 cattagttca aggaaagtat ccaaaagcgt ttcattgtgt cgaacggatc aatgagtatc
     6001 ttcgacaaac gcaaaaacag gaaatgggga tcgcagagca gatttattta acgattcata
     6061 ttcaaagagt agtaagtgag aaaaaaagca tccaatcata aggattgtta ctgtatggca
     6121 ggcaaaacct ggattgaaaa aataggttca cgaatgtttg tgactgtttt tttcaatctg
     6181 ggtttttatt ttttaaataa aaaagaaaga aggaaaaaac aatggataat caagcagttg
     6241 gtcgtcgtgt atgggaagcg gtaggaggac aaaagaatgt caaaagttta gtacattgtg
     6301 ctacgcggtt gcgattcaga ttaaaagatg aatctttagc agatacgcaa aagttaaaag
     6361 aagacccgga cgtgatccaa gtcgtacaaa gtggcggtca gtatcaagta gtgattggca
     6421 gtaatgtagc agatgtttat caatcgatcg tggatgagga aggtcttgca gtttcggagg
     6481 atggaaaaga agagtccaaa aatattttga atcgtctgat cgatattatc tctagtatat
     6541 ttacaccttt tctaggggcg atggcagccg ccggggtatt gaaaggattc ttatcattgg
     6601 caacggtgat gggctggctg acagctgata gcggtactta tcaaatattg tttgctgcag
     6661 cagatggtgt ctttaccttc ttacctgtca tgcttgcttt tacagcagct aaaaagttca
     6721 aagccaacca gtttttagca gtagcaattg ctatggcact tgtgtatcca gctatcacag
     6781 cagttgctgg tgcgggagaa gctatcagtt tctttgggat cccagtgatt ctttcaccat
     6841 ctggttatac ttcttctgtc ataccaatca ttctagccgt atgggttcaa agtaaattag
     6901 agccattcgt aaaaaaagtg attccgcaat ttctgcaaat gattttagtt ccgcttgtcg
     6961 ttttagtagt gatggttcca ttaacatttc ttgctttagg accaatcggg acggttgccg
     7021 gtaatgcttt aggcggtctc ttcaactcga tttatggatt tagtccaatc gtagcaggtc
     7081 taatcatggg aagtttatgg caagtattcg tgatgttcgg catgcattgg ggattcgtac
     7141 cgatcatgtt tttgaatatc gaacaatatg ggtttgatgt attgatgcca atgcttcttc
     7201 cagccatctt ggcacaaggt ggggctgctt tagctgtagc attgcgaaca aaagatacga
     7261 aacttcgagc attagggatt tcttctacag tgacttcgtt atttggaatc actgaaccaa
     7321 ctgtgtatgg tgtgacatta cctttgaaga aaccattcat tgccgcttgt atttctggag
     7381 gtattggtgg agctattatc ggattttccg gagtaaaagc tttctccagc agtttggtca
     7441 gcttattgac gattccgact ttcattaata cggtggatgg tgtagagtca aatgtgacag
     7501 tagcagtaat agctacagga attgcttttg ttcttgcatt cgtaggtaca ttgattttag
     7561 gatttgacga acaaacacaa gacaatcaat tagaaaacaa acatgcgaat gcaggagaac
     7621 cgattacttc agcacggcat accttaaaaa gtcctttaac gggtaaagta ctgccattga
     7681 gtgaagtacc agaccaagtt ttttcttctg gcgtgatggg aaaaggtatc gctattgatc
     7741 cagaagtagg agaactagtt gcacctgcag acggagagat cacgactatt tttccaactg
     7801 gacatgctgt agggatcaca acgactgacg gagcggagat tttgattcat atcgggatgg
     7861 atacagtaga attaaatggg aatggctttg agatcttagt caaacaaggg gatctcgtca
     7921 aagcaggaga tttattgatt cgttttgaca tcgaagcaat tagagcagct ggctatagcg
     7981 taatcactcc agttgtcatt acgaatactg atgcatttgc cgatatactt gaattagacc
     8041 aaaaagagat tattgcaaac gaagatgttc tggcaattgt aaaataagga ggaaatcagg
     8101 atgcaatcac gtttttcaga aaaattttta tggggtggag caactgctgc caaatcaatt
     8161 agaaggggct tatgatcgag acggaaaagg actatccgtt gcagatgcta tgcctggagg
     8221 taagcagcgc tttgcgatta tcggcagtga agaatttgac tggacgattg atcaagaaaa
     8281 atatatttac ccgaatcatc gaggaatcga tcattacgat cgtttcaaag aagatcttgc
     8341 cttgtttgcg gaaatgggat tcaaatgtta tcgtttttcg attgcctgga cacgaatttt
     8401 tccaaatgga gacgaaggta ctcctaacga agcgggatta gaattttatg atcagctgat
     8461 tgatgagtgc ttaaaatatg atattgaacc tgtgatcacg atttctcatt acgaaatgcc
     8521 tcttcatttg gcaaaagaat acggtggctg gaaaaatcga aaactgatcg acttctatga
     8581 acgatttgct cagacagtat tagagagata cagcagtaaa gtcaaatatt ggatgacttt
     8641 caatgaaatc aattcggcct ttcactttcc agctttaagt caaggattag taaaaagcaa
     8701 tggagcagga gagtaccaaa atattttcca agcatggcat aatcaattcg ttgcaagtag
     8761 caaagccgta aaaatcggcc acgaattgcg ttcggatatc caaatcggct gcatgattat
     8821 ctatgcaaca acttacagca tcgatgccaa tccagtcaat caggcagcaa caatgatcca
     8881 aaaccaagaa ttcaattttt tctgcacgga tgtccaagta cgtggagaat accctgcata
     8941 cacagcgcgt acccataaaa aatatggagt cgatccggaa aaattagagc aaacggaaaa
     9001 agacttccag ttgctaaaag aatatccagt ggactacatc ggatttagtt attatatgtc
     9061 tacggcaatc aatgagactg atccacaagc agcaacttca gaagggaact tgctgggagg
     9121 agtaaaaaat ccgtttcttg aggcaagtga atggggctgg cagatcgatc cagaagggct
     9181 gagaatcgca ttgaatgaat tatacaatcg ttaccagaaa ccattattca ttgttgaaaa
     9241 cggtcttgga gccattgatc atatggaaga ggatggcacg attattgatg attatcggat
     9301 cgattattta cgtcgtcata tcgaagcgat ggctaatgca gtagcagacg gtgtagattt
     9361 gatgggctat acgccttggg gatgtatcga tcttgtcagt gcatcaacag gagaaatgag
     9421 taaacgttac ggctttatct atgtggatct agacgatgaa ggaaatggga cactgaatcg
     9481 atcaaagaaa aaatcttttg attggtataa agaagtaatt gcctcaaatg gcgtaaactt
     9541 gtaattaaag cagctgaatg aaaaagaaca cacttctcac atgtgatttg tgttcttttt
     9601 ttatttttta tgtgctattc ttttagtaat agtaaagcaa agggtgacgt tatgaaaagg
     9661 acacgtgtac tatacttgga agtcgcagat aaaattaaag aagatatttt ctcaggaaaa
     9721 tatccagtcg gttcgatgtt gccgacagaa agtgaattag aagaactgtt tcaagtcagc
     9781 aaaatcactg tccgaaaggc aatcgaactg ctggcatcag atgaatatgt cgcaaagaaa
     9841 agtggtcgtg ggacgacggt tctaagcaat cgtccttaca atcgattatc caaagcggca
     9901 agctttacgc aaatcttgga gaactcccga tatgaagtcc ggaaagaaac gctggatttg
     9961 caattggtcc atataaagaa ggaagatcct ttgttttcct ttttcggtga gcaagctgtt
    10021 tgttttaagc gcttatatta tttgaacaat cagccttata tttattttgt tcattatctt
    10081 ccacaagaaa tgatgcaatt cagcagagaa gaatttggca aagaatcttt gtatcgtttg
    10141 ctgacgaaaa aaggatatac tattgactca ttttctgatg atttctcggc agtattttta
    10201 acagaagaag aacaaggaat tctgaaaaca gacgcacaga tcggcatcaa acggatacgg
    10261 aaatcgtcta cgcaaattgg ggaaatgatt gaatattcgg aggcggtcta ccatacggag
    10321 ctgcatcctt accatattga ttatgaaaca taaataaaaa aagaggttgt gaaaaagctg
    10381 ccctgcatca agtaataaga acagccaaac aaaaatagct tctcatattt ttcgtttggt
    10441 taggcttatt accgcagata cacggctgtt tctggattac catttattct ggataagggg
    10501 gtgtggcacg attttcagaa ggaatctatg aaccaatcac tgtattgatt ttagcttcga
    10561 tggtaacccc attcggcttg acgatcgctt atttcttagg gaaaatcatt cgtaaaaata
    10621 tactcaatcg tcaagaaatc gatacattga agaccgcttt tcctatgggg atctgtcaga
    10681 tcacagaggg atgtttccct atcgtattga acgacttggc acgcaatgtc atagcaacgg
    10741 gagtcggtgg gacagtaggt ggcggattaa gcatgttttg gggcgcagat agccgtattc
    10801 cggcatcggg aatgtttgca gtcgctacga tgaccagacc atgggcattc attggtgcat
    10861 tgttagctgg ttcttttgtc acaggaataa ccattttatt attgaaaaaa ccagtagatc
    10921 cgaatgcaga aatcatccaa gaagaaaaag aggaagaaga catatcttgg gatgatttga
    10981 caattagtta ggagaggcag aatggattac aagaaaaaag tacaatagat gtaccttgag
    11041 acaggaatgg tatgaaagaa tcagagttag aaagaatcga atatacagat tttggtttag
    11101 gagcgatcga aactgtccag agcatcggca ccctccttga aatgacgatg aaggaaaaat
    11161 gagaaccttt cgttgtcgaa agggtctggt ataccttatg tcgaaggaaa ggaaacaaaa
    11221 aaactttcct gtactattcc aaaaaggaaa gaaagttatt atacagtaaa aaaagaaatt
    11281 attcttcatg ctagagatca gtacacgttc gagcccaata tcaaacacta gttccaggca
    11341 ggcgcaacag gtgcggttat cactgaattt tcttccagca gtgacgattc aagtgatatt
    11401 tttacaaatc cagctattta tcgttaacaa aaagattttt aggagaagct gatgaacaaa
    11461 aatgatcaaa ttttgatcgt ttagttcgtc ggctttttta tttagagaaa catcatttat
    11521 cagtgaaaca taacacgaga acaaaatgat tttttcgtta ataaaagaaa caagtatttg
    11581 ttgtttaaaa taatacacgt tattggcata taggacgaaa tcccagtatc ttctataagt
    11641 aagtcatttc atatcgatga aaacacgtta tttatttttg ttttatctat aaaatggctg
    11701 aaaaatgatt tttttctaaa tactatatat agtggcgtct atcctatata ccactaaaaa
    11761 actacaaaat ctagtctttt attttaaaaa aacacgtgta gaatgaagat agacttttga
    11821 gttagggagt gtttttttat gaaacttact gttttttgcg gttcccgttt tggtaataaa
    11881 gaaagttaca aatttattgc gcaaacgtta ggaaaataca tggcacaaga agaaatcgaa
    11941 ctggtttacg gtggttcata ctccgggatt atgggagtga ttagtaaaac agtactggaa
    12001 aataacggaa aagtcacagg tatctatccg aatgggcttt ttgaaactga attgcctgga
    12061 aaagatgtta ctacatttat tcctacagaa acgatcgatg aaagaaaggt attattattt
    12121 gaaaagggag atgctgtcct cgttttccct ggaggtctag gtacattgga ggaattctca
    12181 caacttcttt cttggatagc aatcggtctg acgcccgaca agccaatcgg aatattgaat
    12241 attggcggtt attacagcgg cttgcaacaa ttattagaaa cttttgcaaa agaggatttt
    12301 atggataaaa aatggttgga tcaagtaatc ttttccaaca atccattgga actggtcaat
    12361 gaattacgag cagtatctat taaaaatcag ttattattga aggaggcaaa ataatgagtc
    12421 aaatatattt agcaggacca tttttttcag aggagcaaat cgatcgagta agtcgtatcg
    12481 aaaaagcgtt ggaggaaaac aaaacagtca caagtttcta ctctccacgt catcaccaag
    12541 aaagcaatta tgaactattc agcgctggat gggcgcagga agtatacgaa aaagatatgg
    12601 aagaactgac aaatgcagaa tttgttgttg ctatccttga ctttgagcat caaacaatcg
    12661 atccaggaac ggcttacgaa ttaggtgtgg caactatgtt gaaaaaaccg atgatcattg
    12721 tacaagaaga gacggtacct acgaacttga tgattacaca aagtctccat acgtatttaa
    12781 aatcagacca agctgtacgt gaatatgatt ttgaaacatt gcctgttgaa acttacgtag
    12841 gcgagtactt atagaagagg aagggttgta tgtcagtgat tttgatttca ggaacgattg
    12901 gtgcaggtaa gagcagtttg acggatatgc ttgcaaaaga gattgattct aaaccatttt
    12961 atgaaaatgt cgaagataac gaagtattgc cgctctttta ttcaaatcct gagcagtacg
    13021 cttttttatt gcaaatcttc tttttgaaca agcgattttt agcaatgaaa aatgctttag
    13081 tgaacgatga caatgtgcta gaccgatcca tctatgaaga tagcctgttg ttccatctaa
    13141 acgctgattt aggtcgggta acggatatcg aagtacagca gtacgatagc ttattagata
    13201 cgatgctaaa cgagttagat gatgttgctc caaaaaaacg gcctgatttg atggtccata
    13261 tcaaagtttc tttggacacg atgctagaac gtatcaaaaa acgtgggcgt gactatgaac
    13321 agctagaaag cgatgagacg ttatatacct attatgaaac gttgaacacc cgctataatc
    13381 aatggtatga agattttgat gtatgtccta aaatacaagt ggatggggat aaattcgatt
    13441 ttgtagaaaa tccagaagat gcaaaaaagg tgatccgtca gatccaagaa aaattagctg
    13501 aattggaagg aaagcctgct ggaaaatatt ttacggataa ccagcatgca aaaggtcaag
    13561 aattaggcta aaaataaaaa accaaacgac gggaaagaaa aatt
//
LOCUS       DADGHT010000081        13282 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.082, whole genome shotgun sequence.
ACCESSION   DADGHT010000081 DADGHT010000000
VERSION     DADGHT010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.082"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            217..1086
                     /locus_tag="JX887_002127"
     CDS             217..1086
                     /locus_tag="JX887_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAX1258097.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1295..2320
                     /locus_tag="JX887_002128"
     CDS             1295..2320
                     /locus_tag="JX887_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAX1258098.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2359..3309
                     /gene="manA"
                     /locus_tag="JX887_002129"
     CDS             2359..3309
                     /gene="manA"
                     /locus_tag="JX887_002129"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAX1258099.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            3403..5106
                     /locus_tag="JX887_002130"
     CDS             3403..5106
                     /locus_tag="JX887_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1258100.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5108..7141
                     /locus_tag="JX887_002131"
     CDS             5108..7141
                     /locus_tag="JX887_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAX1258101.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7152..7592
                     /locus_tag="JX887_002132"
     CDS             7152..7592
                     /locus_tag="JX887_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1258102.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(7792..8919)
                     /locus_tag="JX887_002133"
     CDS             complement(7792..8919)
                     /locus_tag="JX887_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1258103.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8922..9599)
                     /locus_tag="JX887_002134"
     CDS             complement(8922..9599)
                     /locus_tag="JX887_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1258104.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9863..11629
                     /locus_tag="JX887_002135"
     CDS             9863..11629
                     /locus_tag="JX887_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAX1258105.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11644..12081
                     /locus_tag="JX887_002136"
     CDS             11644..12081
                     /locus_tag="JX887_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAX1258106.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12094..13245
                     /locus_tag="JX887_002137"
     CDS             12094..13245
                     /locus_tag="JX887_002137"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAX1258107.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
BASE COUNT         4506 a         2305 c         2743 g         3728 t
ORIGIN      
        1 aaataggagg agctattttt gtttggctgt tcttattact tgatgcagaa cagctttttc
       61 acaacctctt tttataagag tttttactca ttaatttaca aaaaacaagc aaaatgcgaa
      121 ttttctcaca ttttttttaa caaaatcaaa gttattgctt gaaagaagaa gaatccatcg
      181 ttaaaataaa gcttgacgta gaggggagca agaaatatga aagattttca attgggggct
      241 gccacctatt taaaaagtgt agccattcgg gtgaaagacc gagataaaat gattgatttt
      301 tacaagaacg ttgttggctt tgatttgaaa agagaagaaa acgaattagc cattttagga
      361 acagaagaag ctggaagtga aatgttgctg ctggaagaaa gtcctagagc gaatgatcac
      421 atgggggtga tcaaaaagct gaaccgtttt tcattgatta tccctagcac agaagaaatg
      481 gcagatatcc tttgtcgtat ccgtaaaatg aattatccaa tcaaagaagc tttagaagat
      541 catggacgta tggggatttt gctcgtagac ccagaagaga atgaattgga aatttaccat
      601 gaagagaata agaacgacca aagagaaatt ccagaaacaa tggatcaaga agcattatta
      661 agaaaatctg aagaaaaatt cagtaaacta tcaacaggtt cttattttga aaaaatccat
      721 ttaaatgtta ctaacttaac aaaagaacgc caatttctta atcatgtact tggtttgaag
      781 gtacataatg aagaagaggg catccatgta ttgaatgaag gagatttcca tgttggtttg
      841 acagaagcta gcggaggcgc aattgatttg cctacagatg aagtgattgg acttgatttt
      901 ctgaaattca tgatcgatac tgaaagcatg gaaggactga ttgctcactt gcagcaacta
      961 tcagttgatt tcttcttaga caaaaagcac acagtactca caatctatga tgctatagga
     1021 atcgaatggt ggttcgtcag tgagccaaaa gaaaagaata aaactgacat tcgatgcgac
     1081 gcttaacttt ttctttctta acgattgtcg catgtctcgt cattttatga acggtcatac
     1141 tatcgcttat tctagagata gaaagagaaa atagtatacc gggggaaact gcgcggtttt
     1201 tcgcgcagtt tttttgtgta aaaaaggttg attcctcata gattaagctt taagcttgga
     1261 ctgtaagaat ctgatagaaa agcaggagaa aaagatgtat ccacacacga aacagcttat
     1321 tttgaaaaag atggaagaag gattttatcc aggtgtagca gtcgccttca taaaagaaaa
     1381 tcaagtagaa acatttacag ccggctttgc ccaagtcgtt cctgaaaagc agctgatgac
     1441 agaagatctg ttgtttgatg cagcctcact gacgaaagtc gttgcaacca cttcattagt
     1501 tttacgtcta ttagaagatg gaaagataga actcgatcaa ccgcttcata aatatcttcc
     1561 tgaatttgaa aatcagacaa tcactttgcg tcatttactg acacatactt ctgatatcaa
     1621 aacatggata ccaaacagag ataagctatc tcaggaagaa ttgatcgccg cttatttgaa
     1681 gctagaacca ggtgagcaac taggaaaaga agtaaaatat acagatgccg gtacgattct
     1741 tcttgggttg atgctagagg aaatttacca agaaactgca gtggaaatct ttcaagaaca
     1801 agtattggaa ccattaggaa tgatgaacag cttatttctt ccttttcctt ccaaaaaaat
     1861 cgttcccaca gaacaactgc cttcgggtga ggttttgcgt ggacaaactc atgatccgaa
     1921 agcaagagtt ttggctgaac atgcaggtaa cgcgggtctc tttattgatt tgaaagacag
     1981 cattactttt gtccaaatgt atttgaacaa gggaaaaatc cgtaatggtc gttttttaga
     2041 agaagagacg attgattctt tactgcaaga tcaaacaccg aaaaaaaatg gctatcgttc
     2101 tttaggatgg gacttaaaaa aggatgtaga agacggtcat gcgattcttt ttcatactgg
     2161 ttatacaggt acgtttttct tgattgatat aaaaacacaa gaagcgttga tatttttgtc
     2221 aaatcgcgta catcctgtcg atcatcgtgc ggagtatctc atatgtcgag atgaaattgt
     2281 tgaaaacttt ttgaaagaga aagcggtatt accgaaataa tgctataata gctatgaaaa
     2341 atgagaggag tttgaattat gcaggaacct atgtttttaa aaccagtttt tcaagaaaaa
     2401 atttggggag gaagtcgttt acgttcagtc tttggttttg atatccctaa cgataaaatc
     2461 ggagaagatt gggcgatcag tgcgcatcct catggtgtca gtgtagtaga aaatggcgaa
     2521 ttcaaaggga aaagattaga tgaactatgg tcagaacaca aggaattgtt tggccatcct
     2581 tcagaaccag tgtttccatt attgatcaag atcttagacg cagaagatga tctatctgta
     2641 caagtacatc cagatgatgc ctatgggatg aaacatgaag gtgaattagg aaaaactgaa
     2701 tgctggtata tcatcgatgc tgaacctggt gcagaaatca tctatggtca tcatgcaaag
     2761 acaagagaag aactagctga gatgatcaaa gatgggcgct gggatgacct tttgaagaaa
     2821 gtaccagtta aaaaaggtga tttcttttat gtaccaagcg gaacgatcca tgctattggt
     2881 aaaggaatca tgattttaga aacacagcaa agttctgaca cgacttaccg cgtgtatgac
     2941 tacgacagaa aagatgcgca aggacaaaca agagagctgc atatccaaca atcgatcgat
     3001 gtaacaactg tccctgcgaa aacaccagaa ttacaaatca aagaagtccg aaaagggaat
     3061 tcatcgatcg tcacttattt agaaactgag tttttcaatg tatatgagtg ggatattaaa
     3121 ggaatcacat ctttcaaaaa acaagcccct tatacattga tgacggtaat cgaaggagca
     3181 ggagaccttg tcgttgacgg aaaaacatat ccattagaaa aaggaacaag ctgtattatt
     3241 ccaaatggcg tttctgagtg ggcggtccaa ggtgaactag caatcattgc gactgaacca
     3301 ggcaaatagt tcccagatag ctgaaagcag cagacggttt ttcgtttgct gctttttcta
     3361 cataaaatcc gtccatcaat aaatagaagt atggtgaaaa agatggaata caaatggaaa
     3421 gcaaacaaca gcagtcgcgt gtctatgaaa caactgagaa aagctggaca tcacttaaat
     3481 gaaatgatca tgccaaatct aagtctgttt atcgcttggg gaatcttgtc attagcaaca
     3541 aaaggtgtgt ctggcgattt gcacaccaca ttagaagagg tatgccattg gatgatccag
     3601 ctgcttttac ccatcttgat cagttattca ggcgggaaat cggtaggggg acaaaaaggg
     3661 gcagtcgccg gtgcaattgc ttctttaggg ttgatcgctc gttccaatgc tccacaaatc
     3721 gtaggagcga tgattatcgg gccgcttgcc ggcatcgtat atgaacaatt tgtttctaga
     3781 ttccacgtga aattcaaggc tggatatgaa atgcttgtca gcaacctact agtaggactg
     3841 actggtagcg ttatttgtat aattggaatc gtttttattg aaccagtttt aaatagtgtt
     3901 cacttgttgc tcgcctccgt tgtgtcttgg ctagtcacaa tgaatctgtt accacttgtc
     3961 agtctgatct tagaacctct aaaagtacta tttttcaata atgcaatcaa tcatggtgta
     4021 ttgacacctt taggaatcga attctcacaa acagtcgggt actcttcctt atttttgatg
     4081 gaggcaaatc ctggacctgg tttagggatc ttactttcta tcctttgttt tgcagaaaaa
     4141 caggaaaaag taaatgcgag tggagcattg atgatccatg cgattggcgg gattcacgaa
     4201 atctattttc catttgtctt gctgcgaccg tatctatttt tagctgtaat ggctggtggg
     4261 gcaagcggca cgttgatatt tcaatggtta gatacgggat tagctgcacc tgtatcgcct
     4321 gggtcactac tcgtgatttt tgccaatgcg ccttatccac aactagctgg ggtaagtata
     4381 gggatagcaa tcagtacatt tgtgaccttc atttgtgcag cgatactatt gaaattacca
     4441 aataaagaaa aagagaacaa aacggtcaaa gaaaggggag aaatcttgga accatctatc
     4501 attcattccg tcatttttgc ttgcgactca ggtatgggat caagtgctat gggagccgcc
     4561 ctgctgaaaa agaaattagc agcagaaaaa atcgatcttt ctgtcggata cagctctatc
     4621 tatgaattga ataaccaagt aaatcagctg gttatcgtgc aacatgaact agcgggtctt
     4681 gcaagagaaa aagtacctca aagtcaaatc tatgtactgg atcacttttt ggaaacagat
     4741 atcttgctgt cacgaataaa agaagcgatc caatttccaa agcgggaaga aaaaaaagag
     4801 atagcagata tcacagaaca aaaaaagtcg cctgctaata ttgtattttt gtataaaaac
     4861 aacagacgcg gctcacaaac tatgggcatg acgattttaa gtcaattagc aaaaaaagcg
     4921 aaaaaacagt ttgttatctc aaaagaatca atagaaaaaa tcaaaatcca agaagaaacg
     4981 atttatatcg cacaaagaga actagctgta actgaacagc tagaagaaaa gatccctcgg
     5041 ctagttctag ttgaacattg ggtagctacg aatgaatacg aaaaactcgt gaagggagaa
     5101 atataagatg tatttatcgc ccagagaaaa acaattatta gcagaatttc tcagtagccc
     5161 gtcacctgta tctatccaaa aaatgatgaa tttattgaag gtcagtaaac ggactattta
     5221 ccgcgaatta gataatcttg aagtctcatt gaaatcggta aatgcttctt tgaaaaaagc
     5281 agctagaggc tcatttgtca ttgaggcatc agaagaagta ttagagcaat taaaagaaaa
     5341 tacagatggg aaaagtaatg acttatccac tgctaaacga caacacgcga ttttagccga
     5401 gttgttactg acgacagagc cgttgagtct tgctcatttc atggaatcat atcgcatcag
     5461 taataccact ttttatgcag atatcaaaca gttggaagaa agtattcgcc aactgccttt
     5521 ggaaatcatt cggaaccagg gatacgagat cgaaggaccg gaaaaatacc gccggcttct
     5581 gacagcgaat gtattagaat tagaaatcaa tgaatatgaa ctttttcata gtatttcttt
     5641 cgatgcatca ctgaattatt tttttcgatt cgttgatccg caacatctat ctcttgcacg
     5701 caaagtaatc ggggaagaat tgatccaaaa aaagaccaat ctaagtgata gaaagcttga
     5761 acatttggtt ttgatgctga cattgacgat ggagcgtgtg actaaaaatc atttactgac
     5821 aaatgagaca tataatagtc tggcaaacaa agaattacta cagacagcta aacgattgtt
     5881 ttcacggatc gcttctgaga caaaacaact ttatccagta aatgagatcg tcttttttgc
     5941 aggattatta aatgacttca cgaactcatt tgatcagaat ttctttgaag agacgttcga
     6001 tacacagctt gcttatttag taaaacaact gattcaagaa gtaagtgaag agacgaatgt
     6061 ccatttttat gaagatgaaa ctttgtacaa aatgctgttg actcatttat ctggtgtgtt
     6121 ttcaagagcc gttttacaag aagagacact gaccaatcca attttagaaa aaatcatggt
     6181 tcaatacgag gaagttgcga atgcaatccg taaagcagta gagcggattt ttcaagaaaa
     6241 aaaattatcc gaagaagaga tcgcttatat ggtccttcat tttgcgaatt cattggaacg
     6301 aagtccgaaa gaaagcaata tcagtattgc aggattttcg ccaagtggat tagcttctac
     6361 tagcatgttg gaactacgat tgaaaaggta ttttcccttc atccaacaaa ttcatttcta
     6421 tcggattgct gatttaaaaa aaatcgattt acaagaagaa tatgatgttg ttatttctac
     6481 atctatttta ccaggatacg gtggaaaata tattttagtc tccccgctac tgctagaaga
     6541 tgaagtcaag cagctaaaag aagctttttc gcatattgag aagaaaaaaa ggcaaaaaat
     6601 tacgtataac agcaataacg agtggatgat agaagatact tatgaggaaa caatgcattt
     6661 catggatcaa atcaatcaat tactcggtcg tttttttatc caagaactgg ataatcctga
     6721 gacgatttcc gaaacgattc gcagcttatt tccttatttt cctgaaggac tagtaacgga
     6781 tgaagaggtg gttcatcgcc ggctgcttaa gcgatatgaa caagcaccta tcggtattcc
     6841 tcatacaaat atggggttat tccatacatc cagctcattg atttctaaac cgatcttttg
     6901 tattttcaat ttgaaacatc cgttgaccat tgaagggatg gatagacagc cagtcgattt
     6961 gtcccgtatg ttagttatgc tggcgccttc gccaatccaa gaaaaagacg ggattctttt
     7021 aggaaagatc agtggagcaa tcatcatgaa tgacttgaac accgagatct tccgctcagg
     7081 aaataaagaa atcgtttatc agttgttagc gaaaatcctg attgaagaaa taaagaaatg
     7141 aaggtgaaaa gatgatacag ctaccagcag aaaaaatatt gctcgatcaa tcctatcaaa
     7201 attggaaaga agcgttgacc gagatcggcc agtggatgac ccaacaaggg ggaatcaaac
     7261 cggcatatat ccaatcaatg atcgaaagac aagaaaaagc gagtgtctat atcgggaatt
     7321 tcgtagcctt gccacatggg actgacaaag atgaagaagt agtagaagaa ggaatctatt
     7381 tagtccaagt gcctgatggt gtggactttg gaacaaaaga ggaaccaaaa atcgcgacac
     7441 tcttatttgt agtggcttta aaaaaagaac atcagttagc ggtgctccaa gatttagcct
     7501 ttttctgttc agacatcgac caagtaatgg cgctcagtga tgcgaaaacc attgaagaag
     7561 tccaaatgat ttttgaacat ggacatatat aaccaatgtt cacagtaaaa aaagctgcct
     7621 tgcatcaagt aataacttca accaagataa aaataagagg agctattttt gttgggaggt
     7681 tcttattact gcggatgcaa gcttttgaaa actatttatt ctagaaaacc gtttatttga
     7741 aataggggac ggtgacaagg tttttgtcac cgcccctatt atttttgtgt tttaatagct
     7801 cttttttata tagatagtgc ccatacctat gaataataaa acgatactcc atataccaag
     7861 tgtcaagata ccattcatga aagtaacctg ttctgaagct agtggcgaga aaatatctcc
     7921 tcctatgatc acattttgaa aatcaacata agaagttggc aagtaatgac tgattgattc
     7981 tatccatcca atcgaagaaa acaagcgata ctctgctaag aaaagacaaa gaagtgtacc
     8041 taaaagattg actagagaat gttcaaataa agcagataga agaaaactga ttgtacttaa
     8101 aaagagcacc cacaacaaca ggaacagaaa gctctggaaa agatactcat acatcggaag
     8161 gattcgtatc tcctgaccaa tgatcgttcc tacaggataa cggaagtctc ccaaaccatt
     8221 tttgattatt actagtatag agacgatcaa aaatggcatc acgagactta gcatagctgc
     8281 accataataa atggtaaaac ggatgctatg tttctttacc atactatccg gtaatagatt
     8341 gactagagag attacctgct ttcttttttc ataagagatg atggaagaaa gaaacaaggc
     8401 ggttatacat aaaatcaaaa aactagaaat cattcctgaa aaaatatttt cgtagtaatt
     8461 tgctaaaggg agatgcgctg gcaagtcaaa aatagaatat ctttggatct gatgttcttt
     8521 catataacgg agcaactcga cacgtttttg ttgttcaatg attggaattc cttgtctttg
     8581 accagaaatc agtcgatcca gtatatcttt ttcataatga taagttgctt cgaccatttg
     8641 ctggacattc cctgtgtttt ttgcatgtaa gattgcttcg atcagtttgt tgcttttctc
     8701 taaactttcc acaaattctt tctcattctc atcttctttc aacgtttcaa tcaaacgttg
     8761 catctcttca tagttatgat tcagttcatc gaattctgta taagcaagtt tatgatcaaa
     8821 aaaaagtggg aatgcaaaga gcacgaccaa caatagagga aataaaaagt ttactttgtt
     8881 ttttagtaag agattgcgtt caaatgtaag taaagacata gttacacctc atataattta
     8941 cgataaatag ctaaaatctc ttccatattt gaggattctg tgacgatttc tccatttttt
     9001 agaaaacatg ctttagaaca aatcgattgg atattcgcga tagcgtggga agaaagaaga
     9061 atcgtcttcc cctctttctg ccattgtctg atgaggctat tcaagatatc aatacttcct
     9121 gggtctaatc cgttcaacgg ttcatcgaat aacatgacag atgaatcact gatcaagtaa
     9181 gcagcaagca agacatgttg tttcattcct agagacattt ttccaatcgg caaagtaagg
     9241 tactcagtca tcttcaatcg ttggaaaaca gtttggcatt ctactttgct ctgccaatag
     9301 tatttgatca aagtcaaata atcaacagcc gatagatagt cggataactg attcgttgat
     9361 tctagaaaaa agaaagaccg gcgataatct gtataagcag taggagagat gttgtgaagg
     9421 gacaattgat cataagttgt tggcagcagt tgggcaatgc cattcagcaa agttgttttg
     9481 ccaaatccgt tcggggcaat caaagcagct acttctcctg attctactaa aagattcaat
     9541 tgtcgaatca cacgtttttt accacgtttc atgttcatgt ttttgatcag taatgtcata
     9601 gataggcctc caatataaaa tttaataaca taatagaatg gaaaacatct aaattaaatg
     9661 ctaacaaaag ttattgtttg catattataa aaaaattaaa ataacagttt tatttaaaat
     9721 tgaagttttc tgataccgaa atctttttat tttgctgaca tactcaaacc tttggcacaa
     9781 agtttcgtgc caaagtacga ctatttctct ttttagtaag cggatacaat tagagtatca
     9841 aaaggagaga gggagagaca aaatggaacg gacgattccc aaaaacaaca tttcgctaaa
     9901 agcgagggta caaaaattag gcagtacttt atcaagcatg gtcatgccaa atattggagc
     9961 actgattgcc tggggtgtat taacggctct atttatccca gatggttatt taccaaatga
    10021 ggctttggct accatggtaa gcccaatgct aacttatctg attcctttat tgatcggtta
    10081 tactggcgga aaagtaattg ctggtgaccg cggatcagtt gttggggcaa ttgcaacgat
    10141 gggtgtgatt gtcggaacag atattccaat gatgctaggc gcgatgatca tgggacctct
    10201 tggtggatat gccatcaaga aatttgatca gctattccaa aaacggatca aatccggttt
    10261 tgaaatgcta gtcaataatt tttcagcagg tcttatcggt tttggattag cgttattagg
    10321 tttttctgcg attggtccag ttgtcgatgc attgactcaa gcaatggcaa aaggtgtaga
    10381 gatcatttta tctgcccatt tgattccatt gacaagtatt tttattgaac cagcaaaaat
    10441 cttatttttg aataatgcaa tcaatcatgg gattttgaca ccattgggaa ctgaacaagt
    10501 agcagaggct ggaaaatcta ttctattctt gcttgaagca aatcctggtc caggacttgg
    10561 cgtattactt gcttttactt tgtttggcaa aggagcagca aaatcttcag caccaggagc
    10621 catgatcatt cactttttag gcgggatcca tgaaatctat tttccttacg ttatgatgaa
    10681 accgttatta ttcttatcag ttataggcgg aggaatgtca ggaagtttca ttttccaatt
    10741 gatggatgct ggactaagag cgccagcttc tccagggtcg atcattgcga ttctagcgat
    10801 gacaccgttc aattcttacc ttcctgttat tttgggcgtg attgttgccg cagctgtttc
    10861 gtttggtatt tctgcagtaa ttttgaaagc ggatgcgaaa gatacaaatg aagacttcga
    10921 aaaatctgtt caagagacaa aggcagctaa gcaagcttcc aaaggtgccc aaggtattcc
    10981 tcaaggagct acattctctg gcgtacaaaa aatcattttt gcttgtgatg caggaatggg
    11041 atcaagtgcg atgggcgctt cgatcttgag aaaaaaagta caggaagcag acttgcctca
    11101 aacggtgacc aatcaagcaa tcagccaact gacagatgac tcgaatacat tgatcgttac
    11161 tcaggtcgaa ctacaagaaa gagcaaaaca aaaagcaccg agcgcgcgtt ttgtctcagt
    11221 agaaaacttt ttgaattcac ctcgatatga tgaaatcatt caagaattaa gcagcaagca
    11281 gaaaacatca gtttctgaaa ttgagaatga gccagcagaa gagtttcttt cagcaaacat
    11341 caaacaaatc aaagagattc tacttgtcca cgatgatcgt tccggatcag caacaatggg
    11401 gatgaccgtg ctcaaagata tattagacaa gaaccattta actatcccgt taagaaaagt
    11461 caatatccaa gatttaaaag atgaacctga ttcactgatc gtagccaaag aaagtttagc
    11521 ggaaaaagta cagatggctg cacctcaatc cattcattta tcagtcaaca gcatggtcaa
    11581 tccgcaaaaa tacgaatcga ttgcacaata tttgaaacag acagcttaag ggaggaaaac
    11641 agcatgcaaa gtttgccatt cgacatgatc gagctcaatc gatcttttaa aaccaaagaa
    11701 gaagcgatcc gctattgcgg tcagatgctt gtagaagcag ggtgcgttga tgaggaatat
    11761 atcgatgcca tggtagatag agacaaaatg ttatctgttt atatggggaa ttttatcgcg
    11821 attcctcatg gaacagatga agcaaaaaaa tatgtgaaaa aatccggcat ctgtgtcgtt
    11881 caagtaccag atggtgtaga ttttggtacc gaagaagaag aaaagattgc gactgttttg
    11941 ttcggtattg caggagtcgg agatgagcat ttgcaacttg tacagcaaat cgcactttat
    12001 tgcagtgata tggacaatgt tgtccagcta gcagacgcgc tcagcaaaga agaagtaacg
    12061 gaaaatctag caattgctta aggagagaga aaaatgagag cagtacattt tggtgcagga
    12121 aatatcggtc gaggatttat tggagaggtt ttggcagcta atggatttga gattactttc
    12181 gtagatgtga atcacacgat cattgatgct ttaaatgaaa gaaaagaata cgaaatcgaa
    12241 ttagcagatg aatcaaaaga aaaaatcact gtaaaaaatg tcaaaggaat caacaatcaa
    12301 acaaatccag aaaaagtaat ccaagaaatc gctgaagcag atttagttac taccgccatt
    12361 ggcccgaata tcttaccttt tattgctgag ttgattgcaa aaggtatcca agaaagagaa
    12421 aaggaaggaa gcacaacatc tttagatatc attgcctgtg aaaatatgat tggcggttca
    12481 gcatttctag aaaaagaagt gtataaatat cttccggaaa catcatttac tgacaaatat
    12541 atcggctttc caaatgcagc agtcgatcga atcgtcccat tacaacacca tgaagatcct
    12601 ttattcgtcc aagtggaacc tttcaaagaa tgggtcattg acgatagcca aagaaaaaat
    12661 aaaaaaatcc aattaaaagg ggttttatat gtagatgatc tagaaccata tatcgaacgc
    12721 aaactattta gtgtcaatac tggtcatgcg actgtcgctt atacaggtgc cttgttaggt
    12781 taccagacca ttgatgaagc aatgcaagat gcgttagttg tggcacaatt aaaatcagtt
    12841 ttgcaggaaa caggaagttt gctgattgcc aaatgggggt ttgatgcaga gcagcatcat
    12901 gcgtatattg aaaaaatcat tcatcgcttc caaaacaaaa atatctctga tgcgatcaca
    12961 cgtgtcgctc ggacaccatt acgtaagtta ggttatcaag aaagatttac acgtccagtg
    13021 agagaactac aagaacataa cttgacttgc ccacatttga cggcaacaat ggggattatt
    13081 tttaattact atgatcctga agatgaacaa agccgtcaat tgcatgaaat gaagatccat
    13141 gaaaacttgg aacaattgat tcaagaagtc acaggaatca atgatccgaa aacaatcggg
    13201 aatatcaagc aaaacgtgaa ccgttatgcc aagcaagtcg cttaaaatag gatacgaaaa
    13261 aggggaatgt gacgaaattt tt
//
LOCUS       DADGHT010000082        13020 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.083, whole genome shotgun sequence.
ACCESSION   DADGHT010000082 DADGHT010000000
VERSION     DADGHT010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13020
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.083"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..2564)
                     /locus_tag="JX887_002138"
     CDS             complement(<1..2564)
                     /locus_tag="JX887_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258108.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIP"
     gene            complement(2786..3670)
                     /locus_tag="JX887_002139"
     CDS             complement(2786..3670)
                     /locus_tag="JX887_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAX1258109.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(3765..4202)
                     /locus_tag="JX887_002140"
     CDS             complement(3765..4202)
                     /locus_tag="JX887_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258110.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(4419..5330)
                     /locus_tag="JX887_002141"
     CDS             complement(4419..5330)
                     /locus_tag="JX887_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1258111.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(5707..6345)
                     /locus_tag="JX887_002142"
     CDS             complement(5707..6345)
                     /locus_tag="JX887_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1258112.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(6349..7119)
                     /locus_tag="JX887_002143"
     CDS             complement(6349..7119)
                     /locus_tag="JX887_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAX1258113.1"
                     /translation="MIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQE
                     ISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSTYWERNILSGEIYPPLK
                     IKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFS
                     FFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIER
                     EPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            complement(7537..7953)
                     /locus_tag="JX887_002144"
     CDS             complement(7537..7953)
                     /locus_tag="JX887_002144"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258114.1"
                     /translation="MMTREKEAYERFILLFVERFNQAFHTDYATNIFEDFENSYSYSV
                     ISSTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNGFSLHQVLWCLLGKKKI
                     IITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGI"
     gene            complement(8004..8385)
                     /locus_tag="JX887_002145"
                     /pseudo
     CDS             complement(8004..8385)
                     /locus_tag="JX887_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8511..9176
                     /locus_tag="JX887_002146"
     CDS             8511..9176
                     /locus_tag="JX887_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1258115.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(9573..11606)
                     /gene="brxL"
                     /locus_tag="JX887_002147"
     CDS             complement(9573..11606)
                     /gene="brxL"
                     /locus_tag="JX887_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HAX1258116.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(11724..>13020)
                     /gene="pglZ"
                     /locus_tag="JX887_002148"
     CDS             complement(11724..>13020)
                     /gene="pglZ"
                     /locus_tag="JX887_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HAX1258117.1"
                     /translation="YRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMKRSV
                     KTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQLTY
                     NEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSVIYI
                     YHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYKRSH
                     VEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPITSS
                     IFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLSTTL
                     EFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEFVNR
                     RYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
BASE COUNT         3999 a         2649 c         2002 g         4370 t
ORIGIN      
        1 gggatagaaa gaacaaattt acctgtatca tcaatagttg tttcggacaa aacagcttga
       61 ttttttttca atgaaaccaa agctcctgct tcgcctgtac ctgtgattga gcgagaagct
      121 gcattgatca atgtggtact taatttagca ggctcaggag gaatcacatc gactgtcgtt
      181 ttggcagagt ccagttctgt cacttcttgg ccgcctctta cttttttagc agcaactatt
      241 tgcacttgat cccccgttgt tagtctttct tcgttgggta cttgaacctc aaacaaaccg
      301 ccttgttcgc cttctcccca cggattatat cctgtccctt cattttcatc tgtttgtcct
      361 tgtgtgagag cagtaatttc tacaggtgat ttcgtcgtat ctgcataagt aatacgtaaa
      421 gtcacttcta cttcgcctgt ccaagcatct cttggctttg cctcgacacc ttcgggaaca
      481 acgacatgcc catagatttt tttatctgca ttcgttggta ctcttaagga ttcaatcatc
      541 ggaagctggt tattggcact gattcgatta taatttttca ttccggcacc tgtctgagca
      601 aattcatttg ttaaacctgc actagggctt gatacaaaat tacctaagtc ggttccattg
      661 atcgataagt ctgtcatatc agaaaaataa tccggatctt tttcaaagtt atcgaacgtt
      721 actcctgcct ttcgccataa agcaatttct gaatgagcga tcttcaaaga agaatcgcca
      781 tttccttgaa atacccagcc acctatgcca ttagtctcgc ttccgatccg tttgttttgg
      841 aaatcgaaat aggtaggaga ttctaagtct acattcaaca catccccact gatgatgcca
      901 gtcttatctt ccccagtttt cccgaccatg actaaataag ttttttcgcc agccataaag
      961 ttcaaatcaa tatctccagt tgtatctacg gtagctccgg aatctgcgcg tatatcgata
     1021 tttgattttt ctccagtaac cgtaaaatca gctgaccctg gactttctag aaaaccagaa
     1081 gcgtcataaa attggatcgc ttggtttcct tgattgagtc tgttcacata agatttgcca
     1141 tcccctgcat ttcttacctt caatgagcct ccattagtta ctgttagttt ttgcgtaccg
     1201 ttctcaaaac gaactgcgct agaacgacca ctttgcttat caatatcgat gactgatccg
     1261 gctccttcta cgatcaaaga aagtcctttc cctacaaaac gcatcccatt gtttccaggt
     1321 tggtcgccat ctccagccat tttgaccgag atttgtccac cacttgatac atggatttga
     1381 ctagaatctc cttgcaggcg aaatccgcca gtagtcgctg tattgattgt gattttccca
     1441 tcattcgaca cagcgactct tgatcctgag cctctcattt ggataattcc gcgattgttg
     1501 tcgttggtaa tattgatctt tgtatttacc gaaaattcac ttcctgagcc actgacttta
     1561 aatgtgacat tcccgggtag cgtatcgaca gcctctcctt catcgctgac gccatctgcc
     1621 cgatcatagt caagagagac ctttgaacca ctcaagatat ggagtcctgg tgctgttttt
     1681 ccactgcccg tctcatcacc tgaatctaga aaaccataga attttcctag atatggtcca
     1741 taaagctgac taccattgat tacatttagc tgatagcttc tacaaaaata agctttaccc
     1801 ggagcggcat tcatcccttc tttcactggt tggacatcca atacaccgga aacaccatct
     1861 aatgtgacag ttgcacgagg ggcgtaaatc aggcctaatt tagaaccatc atataagtca
     1921 agtgtcccgg taaattttat ttctcccgta aaatgatatc tgtttcccca aaaatcggac
     1981 atataagcaa tgataatggc atttccatcg atatttggta tcaacccacc tggatgagct
     2041 gccgttcctt taaaattctg aaactcgatc gactgaggtg tctcattgat atagatgtga
     2101 tgtgtgccga aattatgagc aagtccgcca aaatcgataa cgatatctcg cttgatctcc
     2161 aattccctgt ctaaagtcaa aggctgagtt aaacgaatct tagctactga ttcgtctgcg
     2221 agaagctgcg tcagttcttc tgttgtggca gcttcgctgt acccatccgc tgaaacaact
     2281 ctaacctgta cctcttcact gctatcagac gtttgttcag ctacttctga ggtctcactt
     2341 gtcttatttt cttcttgcct tgtattagaa gtaggcgcct cactttggga ttctgtagtt
     2401 tcagaagtaa ttgattcttc tgaaaaagta gtcttgtcaa aactttgatt ctctgattgc
     2461 gttgattcgc ttgttttctc tacatcggca aaaacggatg tcaccatcaa gagagggaag
     2521 acaaacaaaa tcgacgcaat cagctttttt acatattgat tcattctcca ccatcctctc
     2581 tgacgttttg acaattttat tttaacgttt taatttattt gtaattgtac tttcatattt
     2641 aaaatatgta tttttatggc aaatttttct gttaggtgaa aatttctttt ttgtacaaaa
     2701 aaaggctgtg acaaaagtct tgtcacagtc ccttattccg aacaaccgat gtcctcctga
     2761 caactcttcg gtcacaacct ccattttaac aataaacctg taaatgtgag ggtaacactt
     2821 tgattgtcac aggtaattta tccccttcat ctccatcaac attcgtcgtc aattcttcct
     2881 catcagctaa tgacacaact aattgctcac aagtaagata ggctagattt ttcgtagatt
     2941 catctactcc ttttaatagg tctggcaatg ttttaagcgt atcgatcaaa gaagaatctt
     3001 ttaaataaac caaatggagc ttaccatcat ccacttttgc atttggaagt aatgtttcaa
     3061 aaccgcctac tgagttagtt agtcctatca gcaagatact gctctcaatt tcttccttct
     3121 ttccatcaac ttctacgtga aacgagtagg attgtgtgga agctaactgt ttgattcctg
     3181 acatgaaata agctagtttt ccaaatttcg tcttcttctc cgcatctaca tcattgattg
     3241 cttcagggat agagccaatt gcgacgacat tcataaaata gtcgtcattt atttttccaa
     3301 tatccaatgg cttgactgat tcaatcgaaa aatgattgat cgcttcctca ggttctagcg
     3361 gtatccctaa tgctcgagcc aagtcattca ccgtacccaa tgggaaaaat ccgaaatttg
     3421 gccgatgttc ttgttcagcg attccactga ttccttcgtt gactgttcca tctccgccca
     3481 tgacaaacac actatgatac ccttccgtag ccgcttcgcg agtaaagttt tttgcatccc
     3541 ctgctttttt tgtatgcaag acgaccactt catcaaacac cgattccaat tttgctatcg
     3601 ctaattgctc aaattccttt gcttgttcac cgcctgaact ggggtttacc actaataaaa
     3661 cttttttcat cactttcttt cccttctgat tgatttcttt aatataacga tagcataaag
     3721 aaaaaaatta ggctgtgatg aagtactgtt catgaaacat tcatttattt tttgacaaga
     3781 taaaataccc atactatgaa actgaggaaa attaaaacaa tgatatagga aataaaagaa
     3841 aatgataggc attgtatacc taataaagta aaaatcttag gtggcagata aaaacacaaa
     3901 aatagcaaga gaatgtaata gcgtttcttc cactttttgt tatcagacct tatagcgatc
     3961 agaggaatac caaatgcata actgaaaaac tcttgatgta ctgttaatat gtcacgacct
     4021 tgaataataa atgcaacaat ccccgctata attagtgtgc ctaataccaa aacggaaaat
     4081 tgatgaatat attttatata caaatgatcc attgtacttc ctgccttttt atttgtgaga
     4141 aaaacaaatc cgtatacgtg aataacttct agaaataaaa gaaatttgca aaaccactcc
     4201 atttatctac ttctacgtgc attttttaat atcgttttct ttatttaaga ttatacagaa
     4261 aaatatctag ggtggctgga ttctaagtaa aaaaaatttt taaaataaaa agaactaaat
     4321 caagtaataa ttaaactact gttgatttag ttctaataaa aagatttaga tgaacagttt
     4381 tattgattta aatagttcat attttttatt tataccgctt atttactact tgctgtacta
     4441 gaatctgaag tgaatgtact caaaacattt tcaaagtctt tgtctttgat ttttacatta
     4501 gcgtctttca atacttcgcc aattacttta ttctggaagg tactgtcact taattttgtg
     4561 tctgttgcaa tttctttcaa ttcttttttg tatttatcca tgtcgttgcc tttgttttgg
     4621 tttttcacca ttttaaccac ataatattcc gtagtataag ttgaagcatt ggtagaagtg
     4681 atcacatcag aaacttgacc atctttcaac ttaaaggctg cttctttgac ttctgccgga
     4741 accgttgtag tagtggaatc aaatttcact tttccgccat cttcttttgt cgtagtatca
     4801 gttgacttgt ctttggctaa tttagagaaa tcgtctccct tatcagcagc tttcttcaca
     4861 tcttttgcat catcttcact tgctacttgg ataatttgag cttccacttc tggatggaaa
     4921 gattcccaag ccgtttttaa atcttcatcg gtcaatttga tatgtttctt tagaccttct
     4981 tgaaaggcta gactttgttt gatactgtct ttgaatgttt gttctgtgta acctgcagat
     5041 ttcaattgtg aatcaaatga atcacccaat tgtttctttg tttgatcata ttgggaatcg
     5101 atttctttgg ttgatacgtc atctccatat ttatcttcaa atacttgata aacgatcaac
     5161 tgttgcacag cggaatctgc tccttgcatt tttttcaagc tatccattac ttcttgttcg
     5221 ctgattgtac cgcctttata actaacggct gttttttcac cggcattcgt acagcctgac
     5281 aataagccag tgcctagtac gatggcaagt gctaaaaatc tttttttcat ttatcaattc
     5341 tcctactttt cgttttttgc gaattgctaa aaacaaaggt gttcaagatg aaaatcatca
     5401 agaacacctt tactaatctg ctcgatacgt cctgaataga tataaggcta cacaatccag
     5461 aaagttcgct cagcagaata aatgtcaagt agcacatcac accttaatat actacttctt
     5521 ttgttaccgt ttttcaagtc tatcttgcgt tccgtattta acgtaactaa ttcttagaac
     5581 aaatgttatc gattttgttt ttcttcttcc gctgttggga tattcaaatc agacactttt
     5641 atgttcgatt ttccagacat ttttttgttg tttttattag aaaaagtttg ttttttcatt
     5701 tgttttctaa agcatgatct tcttgtttcc tattttggtc agatatggat catgcgtgac
     5761 cacgataact aacgtacctt gggaagcctg ttgcgataag atttcaacga cttgctcctt
     5821 atttcgttta tctaatgatc cagttggttc atcggctaaa atgattttgc tattcttcaa
     5881 taagactctc gcacaggcga ttctttgctt ctcaccacca gataatgtgt agataggcgt
     5941 acttagcttc ttgtttatat ttactttttt caatgcctca tactttgctg ttcgcttatc
     6001 tgaaacattt aaattcgaaa acttcaatcc aatatctaaa ttaaaatcga ttgtttcata
     6061 ttcaatcaac ccaaaatctt gaaaaagaaa agagagggca tttcttttta tcaagcgctt
     6121 ctctcttcca gttaaatgtt ttgtttcttg attaaataaa taaaattgcc ctgaactgaa
     6181 ttgatcattc aatcctaata tattcaataa agtacttttc cctgctccgc tctctccaac
     6241 tacagtcaca aaatccccag catccgcagt gaaacgatcc aaatgaagaa tcgttttgtt
     6301 tcgaatgatt tttttcgcac cttttatcac tatcaacggc tccaattgtt aacctccatt
     6361 catcagcaat aactgacttt tcttttctgt agacaaaata aaaacaactg aaagaataaa
     6421 atcaatgaag ctaaagaaaa aaatattaaa aagatattta ggctctcttt ctataagaaa
     6481 aaggaagatt acacttgtcg ttccccattt gatgaggttc atcatgaaga aatctttata
     6541 cgtttcaaag agcgaataac cacttgaacg aaagatagcg attttccgac aattgtagac
     6601 aaaatatatg cataacatga catagctcaa caagaagaaa gaaaagaaag tgagtaaaaa
     6661 tatctgtatc aagtaatgaa atgatctgct taacactttg acagctatct cttcagtctg
     6721 agtatacgga aatgataact gcaagttatc acgtaactga ctttcttcaa tcagctcaaa
     6781 taacctttct ttcgacaaag agcctatctt gatctttaac ggtggataga tttctccgct
     6841 gagaatattt ctttcccaat acgtactgtt tttcaatgtc agtatttcaa caaccggata
     6901 atgttcgatc caggggatag aaggaataaa tgtataaatg ggttgattgt tttttataaa
     6961 tagaaatttc ggttcttttt cactgatttc ttgataatat tctgttattt gcgccaggtc
     7021 attttttaaa tctgtatgtc tatatcgttc agggatcaat ataacagggt gcgtttcttt
     7081 ttcggttatt tggatcaacc ttccagagac atcaatcaaa ggaaatttct taagataatt
     7141 cagatttatt tttatccctc tgccaaactg ttcattttct tcattcaagt aatctgatac
     7201 attgactaat atacttccgt ttttattcaa agtttcatat aattcctgat cggctgctga
     7261 tgcaaaacga ttggaataaa taaaatccac gtggtttttc ccgatggtta ctggataaaa
     7321 tacatgatag tcctcaccag cgatttcttt tggtgtttca tgggaaacag ctaactgtga
     7381 agaagaaaaa acgatagttg ctaattcgac attggcaacg gtcaaaagaa gagaaaacaa
     7441 caatccaaat gtaaaaagaa tgtattggat atagttgaac gcttctctta acgaagcgat
     7501 tttttcaact aataaaagag aaatcaaaga gataccctat attccgctga acaagaaaac
     7561 gtacatctgg aacaaataaa gaaattgctc cttataatac ataaaaataa aaccaccaat
     7621 gattcctgca attatgaatg taataatgat tttctttttc cccaataaac accacaatac
     7681 ttgatgtaat gaaaagccat tattcaacaa taaactgatt tctttattca tcaataagaa
     7741 aaaggatgat aacaaaagga ataaaagaat caatccaata gttaaataca ctcgataatt
     7801 atatacgtct gtacttgaaa taaccgaata cgaatagcta ttttcaaagt cttcaaaaat
     7861 attagtggca taatcagtgt gaaatgcttg attgaatcgt tccacaaata gtaaaatgaa
     7921 ccgttcatag gcttcttttt ctctcgtcat caagaaaaat tcaccttcaa aatcttttat
     7981 tttgatcgat tcttcaatgg acgttacgcg aaaggaggta ttagaatagg gtaccttctc
     8041 gtgagaagat ttgacatccc cttgataata caatgtcatt tcaagctttg gctgtatctt
     8101 gaagttccaa gatgtatcta cttcattgga ttcatttact gtttttttca tataagaaag
     8161 ctcagtttct gatgagacat tttcaaatac catgattagc tgctcatatt cttcttgccc
     8221 aataaaatgt tgtggcaatc gaatcggagt ataagtatct gtttgatgga aaaattcatt
     8281 tgtccgatag agtacctgtt tatttataat aaccaaggca aaaccactca tgataccggt
     8341 cactatgatt gtgagtaaaa ctgtgaactt ttttttgatt atcaccactc tcccttactt
     8401 aaatgattct ttgataaaat cataccgttt ttcatcaaaa aaacgtatct atcaaatgta
     8461 taggtcatgt agaataaatc tatatactgt agaatcgaaa ggagaagaag atgaacatcg
     8521 gagaaaaaat acgaacttac cgcagaaatt gtaagcttac gcaaaaagaa ttaggcgaaa
     8581 aaatcggtgt ttccgataaa acaatctcta gttgggaaaa ttctcgtaca atgccagacc
     8641 ttgaaatgct gtcactttta catcagactt taggtctgcc gattgatttt ccttctattg
     8701 aatcagctac cgaatcaata gaaccaacat tgccggatga acctcttgtt atcaagaaat
     8761 cttattcatc aaaacaaccc ttctcactca aaaagacact atctttcttt ctgctcgtct
     8821 tttgtttggt ctatcttttt cttatcaatt atcaatataa aaatgaaacg gttgatcgat
     8881 tcaatccttt tttgaaacca caaatcggct ataccacact ccctgtagga tacgtggaaa
     8941 attccatcga acattgggta tgtaatgata tctttgttca tggtacatgg ctgtcttttc
     9001 acgctggaga ggtagaaaaa ggtaagaatc atgctgtaat caaacacaaa ggaaaacacg
     9061 tcatgaacgt tcgcctgctc acttgggaag ccattccctc agattaccaa gaaatcctca
     9121 tccaagacta tgacgatgcc ttaaaaagaa gccctcagga gccagatagg cattaagtag
     9181 gagatgaacg tagagataga aaaaatcaat gcacatgatc ttatcaaaaa aaaacagggg
     9241 tacaaattaa ttgaaaaagc tttgagatga aagttcctaa ataaaaaagt tcagaatgat
     9301 aggtaaaaaa atgactaact attctagtat taggctattt gtattattct tctgttattt
     9361 ttatatcaaa aaatccagaa ataactaaat ataggtattt ctggcttata gtataatatt
     9421 tacgccacag cccccaatga ttctttttgg aatcatgatc aaggacggac atacacaaaa
     9481 atattttgcc cattcgatcc gaatagatta acgactaatc tagtaagtaa tatagattgg
     9541 tacgtagtca aaccagcaaa tggaaaagtt gtctattcca ccccaagggc tttaaagaca
     9601 gcatcttccg gcgtttgata aaaaatcaaa ttaaaggtac ccattaattc tgggggtaca
     9661 gttccaatat cagcagcgct tatcataggt acaagtactt ttttcgctcc ggcatctttt
     9721 gctacttgta aacagttagc taaattatct accttaatca tagaaccacc aattgtaata
     9781 tcccctaaaa taactaaact tggtaataca ggtttattta aggaaactga gcataaagct
     9841 attatagttg ataacgataa tgtttttgtc ataccaatgc cattcatatc ttgaacatga
     9901 acgacaaaat cttttgtcgt caaactaata gactgactaa cacttccata attagctctt
     9961 aaatatcggt atgccgaatc catcgcttct cttgctccag catctgaatt gatcccagta
    10021 cgttcaaact ttccatttcc cgaagtcatt tgcgtttcca atttataggt acctaattgc
    10081 ccagttttgc cataagatac cgtgtacaaa tgccctggct tccctaaccc ttctggaatc
    10141 aaagttcctc caccttgttc aggaacagaa acatactctt ctcgctcttc ttctaaatca
    10201 atgtatgaaa aattgacatc ataaaattcc attccaccaa ttttctttaa ttgttctttt
    10261 acacgacgac gcatttcaag agcaaatctt agtatttctt cgacatcact tttttcaaat
    10321 ctaccatcag gatacaacag tttcatcatc ccagatacaa tccgacgaac tgcaatcgta
    10381 tcccgctgat ttaattgaga accaagtttg aaatatttat caaaactatc gccaaaacta
    10441 acttttcgaa gctcacgcat gacttcagaa aaataatctg taatgaagcc atagtcattt
    10501 gtaaaaaaat ctggtcgata tttaggaatt tcccaacctg gtaaataaca atgcatccga
    10561 tccaaaaagg ctgaatccgt ccccataacc tccggaaatg gctcaaataa attcgaagtt
    10621 ttcaatatta catcaacgct ttgattaata tttcctacaa aagccattga tgctgaagca
    10681 ttcttttctt ctttgcctct agcaaaagat cctgaagcca tgtaatcttt catgatttga
    10741 acgccatcat tatccttaaa tttaatccca gcaacttcgt caaaagcaac acagtcccac
    10801 atacctacaa gtcccattgt acgactagcc atattataga aaaggtttgc tactgttgtt
    10861 tgtccacctg aaacaaggat tgagtttggt gaaatttctt tatatacatg cgatttacct
    10921 gtaccacgtg gtcctagttc acagagatta aaattatttt caattaatgg aataagtctt
    10981 gctaaatgaa gccattttac ccttttatta aattgtgtag gttccatacc aatggaccgt
    11041 agaagtaagt caatccattc atttgtagta aactccttgc gagccatctt gtaagcctca
    11101 atgtctaaac caggcatttg gattggatca accttttttg caataaaagg gctattccaa
    11161 cgatcattct catcatacca atattccatc gaaacaatac accagatccc cccacctaat
    11221 aatcgatcaa attttttcgg atactcttca ctaatttgaa cattttttaa tcccaggtta
    11281 gagaattctg cttcataaca atctttcttt tcatttaaat gtacagttac tttatcaata
    11341 actgtataac cacccaattc acgaattttt gcttttactt tttctgcttc atcaggacgc
    11401 acatagtttc gagcaagaat atttttaaca ttttccacac ctttttcaac caatgtttca
    11461 tccaatgacg aagcatacat accaagtaaa tattccaata cataaacagg tacattcgca
    11521 ccttctttaa ttttctttgt taaatctttt ctgacaatct ttccgggaaa gaattcagat
    11581 aactttaaaa tttcctgttg ttccactaga attcctccat gtgttcagtc attataatag
    11641 caattaaagt atatcatact taaccagtag gcttgataat acaaaagaaa aagtatccac
    11701 aaaaaattgt ggatacctcg tttttatata tcaaaatcaa atgattctgc aaaaggatta
    11761 tctataatga attttattcg ctcggtcaaa tcattttttt gattttttat cactaaataa
    11821 taagtatctt caactgtata tcgacgattt acaaattcaa aaacaaattt agtaaaccgc
    11881 tgatttgcat cttctgtttt tgaatccgca acatagattt cttcatttga gatacgttca
    11941 ccatattcat cttcaaaata aagccagaaa gatgcggggt cataaacatc actaattgca
    12001 tttttttgat agaattctaa cgtggttgat aatcctgtaa ttctgcggtt gctagtcatt
    12061 aattcaattg ctactggttc ctttgcattg ctacctttgg ctaccgtaat ttctagaaca
    12121 gggactagca tttcttgaat agatgaccct ccatgaacgt agctttgtcc cccgccagct
    12181 ttcttaaaaa tacttgaagt aatcgggaca caaatgtttc tagtgtcatc atttcctaaa
    12241 gaatctccca aagagtaatt tttcgtacca attatttcgt attcttcttc actaagaata
    12301 aaacgacgtt ctacacgatc tttttcattt ctagatggat tttcaatctt atctacttct
    12361 tcaacgtggc ttcttttata aataaatcca tgatcagccg taactataaa acgatagata
    12421 ctgccatcat tatgcaagcg attaataagt cgggaaattt cgcttatcgc taaatcacag
    12481 gcctcaaaaa ctcgattttc attcgagtga tcacctgttc tatccacttg atcgtgataa
    12541 atataaatga ctgatttgcc attaaatact tctcgtacct cagccttatt catcttaacc
    12601 acatcatcat aatttaaagc tacagcattt gcatctcgtt gctggagaat cgcatttcga
    12661 ttggataaac cattcgtttt tttcccatca atcagtactt ctgttccttc attgtaagtt
    12721 agttgattgt ttggtaataa ggcggcttta ccgaattcag taactgaagg taatacagaa
    12781 agaaagctag ccatgtttgt tgaatacttc ttttctctaa ctaacttacg ttctaaattc
    12841 atccctaact catatcgaaa agcatctgaa ataataacta cagttttaac agagcgtttc
    12901 attacagctt gattataaaa ttttcgaatg gatggacgat tcttaaattc aaaagtttga
    12961 ttccaaattt gtcctgattg atcaagaaac ttcgaataat ttgcttcaac taatcgatac
//
LOCUS       DADGHT010000083        12738 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.084, whole genome shotgun sequence.
ACCESSION   DADGHT010000083 DADGHT010000000
VERSION     DADGHT010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.084"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="JX887_002149"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="JX887_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAX1258118.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="JX887_002150"
     CDS             complement(323..892)
                     /locus_tag="JX887_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAX1258119.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="JX887_002151"
     CDS             1078..1980
                     /locus_tag="JX887_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAX1258120.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="JX887_002152"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="JX887_002152"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAX1258121.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="JX887_002153"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="JX887_002153"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAX1258122.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="JX887_002154"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="JX887_002154"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAX1258123.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="JX887_002155"
     CDS             8548..8733
                     /locus_tag="JX887_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAX1258124.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="JX887_002156"
     CDS             complement(8795..9991)
                     /locus_tag="JX887_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAX1258125.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="JX887_002157"
     CDS             complement(10161..11597)
                     /locus_tag="JX887_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAX1258126.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="JX887_002158"
     CDS             11890..12699
                     /locus_tag="JX887_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1258127.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3803 a         2673 c         2250 g         4012 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgacaatt
//
LOCUS       DADGHT010000084        12738 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.085, whole genome shotgun sequence.
ACCESSION   DADGHT010000084 DADGHT010000000
VERSION     DADGHT010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.085"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            97..540
                     /locus_tag="JX887_002159"
     CDS             97..540
                     /locus_tag="JX887_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAX1258128.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(546..1730)
                     /locus_tag="JX887_002160"
     CDS             complement(546..1730)
                     /locus_tag="JX887_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAX1258129.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            1998..2696
                     /locus_tag="JX887_002161"
     CDS             1998..2696
                     /locus_tag="JX887_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAX1258130.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2703..3380
                     /gene="nth"
                     /locus_tag="JX887_002162"
     CDS             2703..3380
                     /gene="nth"
                     /locus_tag="JX887_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAX1258131.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3506..4039)
                     /locus_tag="JX887_002163"
     CDS             complement(3506..4039)
                     /locus_tag="JX887_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258132.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4336..6717)
                     /locus_tag="JX887_002164"
     CDS             complement(4336..6717)
                     /locus_tag="JX887_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAX1258133.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6707..7354)
                     /gene="recU"
                     /locus_tag="JX887_002165"
     CDS             complement(6707..7354)
                     /gene="recU"
                     /locus_tag="JX887_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAX1258134.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7418..7957
                     /locus_tag="JX887_002166"
     CDS             7418..7957
                     /locus_tag="JX887_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAX1258135.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8047..8466
                     /gene="gpsB"
                     /locus_tag="JX887_002167"
     CDS             8047..8466
                     /gene="gpsB"
                     /locus_tag="JX887_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAX1258136.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8488..8855
                     /gene="rnpB"
                     /locus_tag="JX887_002168"
     ncRNA           8488..8855
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="JX887_002168"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9064..10230
                     /locus_tag="JX887_002169"
     CDS             9064..10230
                     /locus_tag="JX887_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAX1258137.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10276..11772
                     /locus_tag="JX887_002170"
     CDS             10276..11772
                     /locus_tag="JX887_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAX1258138.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11853..12536
                     /locus_tag="JX887_002171"
     CDS             11853..12536
                     /locus_tag="JX887_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAX1258139.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2230 c         2630 g         3605 t
ORIGIN      
        1 tcttggtttc agattgggtt ttcctacaaa atatttttat ctttgttgaa taggaaacaa
       61 aaaaacaata taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca actgctaata
      121 gaagaatatc tggatttagc taatgagatt attcatcgta ataaaccaga aatggaaaaa
      181 gaatttgcag gatttactct aaatgaacta gaagtgattg aacatatcgg gaaaatccct
      241 gatcctaacg tgacaaaatt agcgaatgct agttacatga ctagaggagc catcagtaag
      301 ctaacaaaaa aactgatagc tagagggatc ataaacactt atcaaagcga agagaataaa
      361 aaagaaatct attttcaatt gacgccaatc ggacaaaaaa taaggaatag acacgagcaa
      421 ctccatcaaa aatgggtaca gcgagatgct actgtatttg aaaatatgtc aaaagaagaa
      481 tttgacacag tatttcgttt tatcggtcga tacagagaat ttatacgaag tagcaaatga
      541 agctactatt ttttattgta gtgataatag gcaaaaatca taagcaaaaa tccgaatacc
      601 gtcggaagaa atggtgctgc agcataaagc tgtcctgcga ttagcgggcc gatgacgcgc
      661 gatagagatt gtatactttg ggtaccgccc attacaagac cttgctggtt atctgagaca
      721 gaattggata gttggccatt gaatacagga gtaaaaatag aatcaccgaa accataacag
      781 ataatcccaa ataaaaacaa aatcggcagt agaagaattc cagataatgt gatgaataga
      841 taggcgagga tttcactgaa catccctatt cttgtgatct gctgttctga aaattttttg
      901 agcaatcgag gcataatgaa caattgcgag acagtatcca agattccaat caaagagaag
      961 cttaaaccaa ccaacccagc cttccactga aaggcgtcaa tcgaaaattg agaaaagata
     1021 gattgaagag agccagctgc caaccaaaca gcaaaacctg ctgtcaataa aggaataacg
     1081 gatgaaatct tgaataattg ttgtaattgg tgaaaaggtc ttacatggga gaaacttaaa
     1141 tctactgaac gtttttttat tggaaggctt tctagcataa atgtgtagcc ataaacggca
     1201 tttaagaaag taaagagtgc tccaataaat ataggaacag aattccccaa ctcagctaat
     1261 agacccccta taataggacc cagcgttgtt cctataccga ctaaagcacc catccatcca
     1321 aaaactttgg ttctttcatt aggttccgtg atgtcggcaa agtaagcata taaggtggag
     1381 atttctcctg ccgtcaatcc ttcaatgata cgaccaagga acaacatcca tatcgaattt
     1441 cctaaaccaa aaagcaaata tccgatactt gatcctaata aactgataat aaggatcgga
     1501 tgacgcccaa aatgatcact taagctaccg agaatggggg cagataagaa ggcagctaga
     1561 gcataaacag acatgagcaa agtgatatag aaagcttgct gatgtatgga gtgagaataa
     1621 ggcagcgtta aaaacggaag tacaggactg acgatagtaa atcctaatcc agtgaataag
     1681 acagagacgt atccaaaaac tttagaatgt ttatttgtga aactgtacat gtaaaaactc
     1741 ctttatgcaa taatgttaac ttggaaacaa aaatagtgta tagtaatttt gtttccttgt
     1801 caacattcta aggaacagcg aaatctactt aatttattta ttccgaaaag tgaagatacg
     1861 catcaaaaac atgaacaaac aaaaatcaag tagacgacat tgtaaatctg accgatcagt
     1921 gaagtaaata gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt atactgtgat
     1981 tgagcggagg agaaatcatg ttgaatttag aaaattactt aagcgctgga caaacagtca
     2041 tatctaatct tttacttaaa aattatcata ggatcggtct acaatctgaa gaatttttat
     2101 ttgttctaca gttgcatatg gcacagcttg aaggagatac tttccctgat ttgcagatga
     2161 ttgctatgga tatgggaatc aaacaagatc agatttttca aatactggat cgtctcgtaa
     2221 caaatggatt tatcaagata gaaacgacga ttgtcaacgg taaaaaagca gatcgatata
     2281 atctttaccc catctatgat ctattaggtg agtatttaaa aacacaagaa aaaaaatacg
     2341 aagaaaaaac acaagaaaaa gaaatccagt cagtgtatca attatttgaa caagaatttg
     2401 gacgcccgct ttcttcgatc gagttccagc ggatcggaca atggctagaa gaagaccatt
     2461 atcagccgga aattttgaag ctagcactgc gggaagccgt attaaatcag gcttatagtt
     2521 ttaattacgt tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt acaaaacaac
     2581 aagtggaaga agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa gtagaacagt
     2641 cagctcaaca agaagaattg ccgaaagtct cactgaaaaa ttggttggag gagtagcgga
     2701 atatgttaag caaacaaaaa acaatggaag ctctagaaac gatgtatgga atgtttcccg
     2761 aagcacatgg agaactcaag cacaataatc catttgagtt attgattgca gtgatcttaa
     2821 gtgcccaggc gacagatgta tcagtgaata aagcaacgcc agatttgttt gcctcttttc
     2881 cgacacccga tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa ataaaaacga
     2941 ttggtttgta tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag ctgattgaac
     3001 gtttcgatgg gcaagtgcca acgtcaagag aagaattgat gtctcttcct ggtgtaggca
     3061 gaaagacagc aaatgtcgta ttgggggatg cattcgggat accagcaatc gcagtagata
     3121 cccacgtgga acgtgtctca aaacgcctga ggatctgcaa actagatgct acggtcatgg
     3181 aagtagaaga aacactgatg cggaaagtac cacaagaatt atgggtaaag acacatcata
     3241 cactgatttt ttttggtaga tatcattgca cggcaagaaa tcccaagtgc gaggtatgtc
     3301 ctttgctatc aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa aaggcgctaa
     3361 aaaagaaacc acgcctgtag acgtggtttc tttaattgca aataaatgta tgaattatct
     3421 tgttattatg gagaaaagct gtttcgttta tcttttttgc atgaaaaagt aaatgtacat
     3481 actcagtagc taggatggta acttattaca atttattgcg ataaaaataa aagttgttat
     3541 ttttattggg aaaatacccg atgtagaaaa taatgccttc caatatacct ataaaataag
     3601 tccagtattc caaaggatta tataaataag tgacgtatct atctaaaggt gtaataaaaa
     3661 tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg gatttgggcg
     3721 gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa aaagtgagaa
     3781 tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt aaaagtacag
     3841 aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat aataaacaaa
     3901 atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa aaaagatggt
     3961 gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag ccttctttca
     4021 aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg ggattattaa
     4081 gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata aacaagtaaa
     4141 tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta agctaaatgt
     4201 tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac agcttggtac
     4261 atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac gcttgtagac
     4321 gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg gtgtatggtc
     4381 atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag gagcagatga
     4441 agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag acgctggctc
     4501 gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc tttgactagt
     4561 agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct ggacatagct
     4621 ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat attgatcttt
     4681 gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt ctgtatttgt
     4741 cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta cgtgtgacga
     4801 ttctgaagtg acaggcgtca tttttttatt gtaacctgtc cacacggaaa tcgaataatt
     4861 tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac caagttttgc
     4921 atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata acccagcgat
     4981 ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg tgatcatata
     5041 agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt ctgttccgtc
     5101 ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat tggcgaaagc
     5161 cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat cttgttcttc
     5221 cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc caagattttt
     5281 taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg ctggaacatt
     5341 acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat tatcccagtt
     5401 tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag tttttccagt
     5461 agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca tcgtagaacc
     5521 aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt ctgcgatgtg
     5581 acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg tggaggcaac
     5641 ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat catatagttt
     5701 cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt agacattctt
     5761 atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga cgatcttagt
     5821 attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat taacagcttg
     5881 atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa cagtatctcg
     5941 tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg cttgaggcat
     6001 cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac caaagtacat
     6061 ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat ttacgtagta
     6121 ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc acgcttcttg
     6181 ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa gtttgatcaa
     6241 ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag agagggcaga
     6301 accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat cttctaccga
     6361 cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt cacgcttttc
     6421 tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag atacggtagc
     6481 gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga aaagtcctac
     6541 acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct tgataaataa
     6601 tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct tcttcacact
     6661 ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat ttgccattct
     6721 tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc aaataaggaa
     6781 tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa gataaaggta
     6841 gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga acactattca
     6901 aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc ccattttgtt
     6961 cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag ggaaaagatg
     7021 ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag acgccattat
     7081 agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca cttctcttag
     7141 gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc gccaacccgc
     7201 gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc ccccgattgc
     7261 cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag gcattcttat
     7321 aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct aggccacatt
     7381 atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa aagtaatcta
     7441 tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc ctaaaatcca
     7501 agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag ggctggaatg
     7561 ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag tagcggaatt
     7621 gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg attttggtaa
     7681 taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag cagattatgt
     7741 cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc acactcgttt
     7801 tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc ctggaaaaac
     7861 gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg aaattcggct
     7921 gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt tgatttatca
     7981 acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa aactagaggt
     8041 gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga attcaaaaca
     8101 aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat catcaaagat
     8161 tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg attgagtgca
     8221 aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca acaaacagag
     8281 gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc aaatcttgaa
     8341 cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc agcacaacct
     8401 aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa aacacgtcaa
     8461 ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga cttgatcagg
     8521 ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc ttagcgaaac
     8581 cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct tcggctatgc
     8641 ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat ccggtggaac
     8701 gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt gtctggaaga
     8761 agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg ttttttctcc
     8821 ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag ggaattaggt
     8881 cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta tttttcaata
     8941 cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta ttcggaattt
     9001 gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat aaggagattg
     9061 tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg gctagaagca
     9121 ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa cggacgtgca
     9181 cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg tacagcagat
     9241 cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt gtttgaaaac
     9301 gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc tgtagctgga
     9361 aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac aaaaaaagca
     9421 atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact gacggaaact
     9481 ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt aactctggat
     9541 acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg agcaccattg
     9601 aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga ccgtccattt
     9661 tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat aggccataat
     9721 atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt cagtcaagaa
     9781 atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat tgaattagat
     9841 attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa tgcagaagaa
     9901 atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt caaaacggat
     9961 aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg agaagaagaa
    10021 actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa aacatggagt
    10081 aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa agcaaccaaa
    10141 aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg gggaactcgt
    10201 ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc aattggatgt
    10261 ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga aatcaatctt
    10321 ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc tgaaaaagct
    10381 agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc aaaaaaaatc
    10441 ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga attgtcggaa
    10501 gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca tcgcgtaccg
    10561 gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca atggcaaaaa
    10621 gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa tattgaatta
    10681 acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga tgttttgctg
    10741 aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga tcagcttaaa
    10801 gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc tgaaacagac
    10861 tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa agtaatcgaa
    10921 caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc atttatgact
    10981 ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga tttcaaaatg
    11041 gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga catcgatgat
    11101 aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga atcacaatcg
    11161 ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca atatcctttc
    11221 tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt ttatcgttca
    11281 ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac ttaccctctc
    11341 catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt agatgttgct
    11401 gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg accaacaaat
    11461 gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg ttattttccc
    11521 tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca gcaagaaata
    11581 gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg gatgtcagag
    11641 catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga tgcaacacat
    11701 gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt taatgtatat
    11761 caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct atagatgttt
    11821 tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg atcgctgatt
    11881 atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat accaaaagag
    11941 ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc tttgtgacgc
    12001 ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat gagaacgagg
    12061 caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa cagatctcga
    12121 tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa gcggccgaac
    12181 tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta ggagcaatcg
    12241 gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt gatcctgaac
    12301 tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca gtgatcaatc
    12361 atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac ggatatgaag
    12421 aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt ctggaatggt
    12481 ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa aaatgatgga
    12541 ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta aaagttactt
    12601 ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt cacaaggaac
    12661 aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt cggaattggc
    12721 aggagaacac cgtttatt
//
LOCUS       DADGHT010000085        12670 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.086, whole genome shotgun sequence.
ACCESSION   DADGHT010000085 DADGHT010000000
VERSION     DADGHT010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.086"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            6..305
                     /locus_tag="JX887_002172"
     CDS             6..305
                     /locus_tag="JX887_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAX1258140.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="JX887_002173"
     CDS             378..1739
                     /locus_tag="JX887_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAX1258141.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="JX887_002174"
     CDS             1761..2021
                     /locus_tag="JX887_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258142.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="JX887_002175"
     CDS             2035..2787
                     /locus_tag="JX887_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAX1258143.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="JX887_002176"
     CDS             complement(2881..3486)
                     /locus_tag="JX887_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAX1258144.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="JX887_002177"
     CDS             complement(3539..4513)
                     /locus_tag="JX887_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAX1258145.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5670)
                     /locus_tag="JX887_002178"
     CDS             complement(4891..5670)
                     /locus_tag="JX887_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1258146.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="JX887_002179"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="JX887_002179"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAX1258147.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="JX887_002180"
     CDS             7161..8558
                     /locus_tag="JX887_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1258148.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="JX887_002181"
     CDS             8639..9079
                     /locus_tag="JX887_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAX1258149.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="JX887_002182"
     CDS             9227..9553
                     /locus_tag="JX887_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAX1258150.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="JX887_002183"
     CDS             9554..10303
                     /locus_tag="JX887_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258151.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="JX887_002184"
     CDS             complement(10383..10838)
                     /locus_tag="JX887_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAX1258152.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="JX887_002185"
     CDS             complement(11265..11540)
                     /locus_tag="JX887_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258153.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="JX887_002186"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="JX887_002186"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAX1258154.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
BASE COUNT         4054 a         2175 c         2588 g         3853 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag
//
LOCUS       DADGHT010000086        12569 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.087, whole genome shotgun sequence.
ACCESSION   DADGHT010000086 DADGHT010000000
VERSION     DADGHT010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.087"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..789
                     /locus_tag="JX887_002187"
     CDS             <1..789
                     /locus_tag="JX887_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAX1258155.1"
                     /translation="TISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELEL
                     HYSYLVKITEEKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQ
                     KANADVEKELYANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIY
                     KIGMTRRLEPMDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQ
                     RKEFFKVSLDEIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            861..1982
                     /locus_tag="JX887_002188"
     CDS             861..1982
                     /locus_tag="JX887_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1258156.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(2064..3836)
                     /locus_tag="JX887_002189"
     CDS             complement(2064..3836)
                     /locus_tag="JX887_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1258157.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(3839..5551)
                     /locus_tag="JX887_002190"
     CDS             complement(3839..5551)
                     /locus_tag="JX887_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1258158.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            5666..6334
                     /locus_tag="JX887_002191"
     CDS             5666..6334
                     /locus_tag="JX887_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAX1258159.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            complement(6401..7189)
                     /locus_tag="JX887_002192"
     CDS             complement(6401..7189)
                     /locus_tag="JX887_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAX1258160.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(7272..8744)
                     /locus_tag="JX887_002193"
     CDS             complement(7272..8744)
                     /locus_tag="JX887_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1258161.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            complement(8874..10067)
                     /locus_tag="JX887_002194"
     CDS             complement(8874..10067)
                     /locus_tag="JX887_002194"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAX1258162.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            complement(10333..10404)
                     /locus_tag="JX887_002195"
     tRNA            complement(10333..10404)
                     /locus_tag="JX887_002195"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10369..10371),aa:Glu,seq:ttc)
     gene            complement(10416..10489)
                     /locus_tag="JX887_002196"
     tRNA            complement(10416..10489)
                     /locus_tag="JX887_002196"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10453..10455),aa:Ile,seq:gat)
     gene            complement(10502..10572)
                     /locus_tag="JX887_002197"
     tRNA            complement(10502..10572)
                     /locus_tag="JX887_002197"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10538..10540),aa:Gly,seq:tcc)
     gene            complement(10577..10649)
                     /locus_tag="JX887_002198"
     tRNA            complement(10577..10649)
                     /locus_tag="JX887_002198"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10614..10616),aa:Phe,seq:gaa)
     gene            complement(10653..10725)
                     /locus_tag="JX887_002199"
     tRNA            complement(10653..10725)
                     /locus_tag="JX887_002199"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10690..10692),aa:Asp,seq:gtc)
     gene            complement(10744..10817)
                     /locus_tag="JX887_002200"
     tRNA            complement(10744..10817)
                     /locus_tag="JX887_002200"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10781..10783),aa:Met,seq:cat)
     gene            complement(10830..10919)
                     /locus_tag="JX887_002201"
     tRNA            complement(10830..10919)
                     /locus_tag="JX887_002201"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10881..10883),aa:Ser,seq:tga)
     gene            complement(10942..11013)
                     /locus_tag="JX887_002202"
     tRNA            complement(10942..11013)
                     /locus_tag="JX887_002202"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10978..10980),aa:Glu,seq:ttc)
     gene            complement(11035..11122)
                     /locus_tag="JX887_002203"
     tRNA            complement(11035..11122)
                     /locus_tag="JX887_002203"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11086..11088),aa:Ser,seq:gct)
     gene            complement(11147..11220)
                     /locus_tag="JX887_002204"
     tRNA            complement(11147..11220)
                     /locus_tag="JX887_002204"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11184..11186),aa:Ile,seq:gat)
     gene            complement(11234..11304)
                     /locus_tag="JX887_002205"
     tRNA            complement(11234..11304)
                     /locus_tag="JX887_002205"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11270..11272),aa:Gly,seq:tcc)
     gene            complement(11306..11381)
                     /locus_tag="JX887_002206"
     tRNA            complement(11306..11381)
                     /locus_tag="JX887_002206"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11346..11348),aa:Asp,seq:gtc)
     gene            complement(11400..11473)
                     /locus_tag="JX887_002207"
     tRNA            complement(11400..11473)
                     /locus_tag="JX887_002207"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11437..11439),aa:Met,seq:cat)
     gene            complement(11486..11575)
                     /locus_tag="JX887_002208"
     tRNA            complement(11486..11575)
                     /locus_tag="JX887_002208"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11537..11539),aa:Ser,seq:tga)
     gene            complement(11599..11672)
                     /locus_tag="JX887_002209"
     tRNA            complement(11599..11672)
                     /locus_tag="JX887_002209"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11636..11638),aa:Ile,seq:cat)
     gene            complement(11686..11759)
                     /locus_tag="JX887_002210"
     tRNA            complement(11686..11759)
                     /locus_tag="JX887_002210"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11723..11725),aa:Met,seq:cat)
     gene            complement(11787..11859)
                     /locus_tag="JX887_002211"
     tRNA            complement(11787..11859)
                     /locus_tag="JX887_002211"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11824..11826),aa:Ala,seq:tgc)
     gene            complement(11879..11952)
                     /locus_tag="JX887_002212"
     tRNA            complement(11879..11952)
                     /locus_tag="JX887_002212"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11916..11918),aa:Pro,seq:tgg)
     gene            complement(11962..12035)
                     /locus_tag="JX887_002213"
     tRNA            complement(11962..12035)
                     /locus_tag="JX887_002213"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11999..12001),aa:Arg,seq:acg)
     gene            complement(12046..12131)
                     /locus_tag="JX887_002214"
     tRNA            complement(12046..12131)
                     /locus_tag="JX887_002214"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12095..12097),aa:Leu,seq:taa)
     gene            complement(12148..12219)
                     /locus_tag="JX887_002215"
     tRNA            complement(12148..12219)
                     /locus_tag="JX887_002215"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12185..12187),aa:Gly,seq:gcc)
     gene            complement(12231..12303)
                     /locus_tag="JX887_002216"
     tRNA            complement(12231..12303)
                     /locus_tag="JX887_002216"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12268..12270),aa:Thr,seq:tgt)
     gene            complement(12321..12402)
                     /locus_tag="JX887_002217"
     tRNA            complement(12321..12402)
                     /locus_tag="JX887_002217"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12366..12368),aa:Leu,seq:tag)
     gene            complement(12410..12482)
                     /locus_tag="JX887_002218"
     tRNA            complement(12410..12482)
                     /locus_tag="JX887_002218"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12447..12449),aa:Lys,seq:ttt)
     gene            complement(12486..12558)
                     /locus_tag="JX887_002219"
     tRNA            complement(12486..12558)
                     /locus_tag="JX887_002219"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12523..12525),aa:Val,seq:tac)
BASE COUNT         4029 a         2700 c         2224 g         3616 t
ORIGIN      
        1 actatttcta atatagactc gactagggaa aaaatcataa aaatatttga taaaattaat
       61 aatttattca agaatgacaa tgctgaatta aggaagggtc ttttagagtt taaacttcaa
      121 gaactagaac ttcattactc ttatttagtg aaaattaccg aagaaaaaga acaacaaaaa
      181 gcaataaaag aacagatgat agaagaggaa aaagttcgta gagaaattga tcgtgaaaag
      241 aaacgtattg ataaagaaca acgtcaattc aattctgaaa tttccaaatt aatcgcatat
      301 atgcaaaaag ctaatgcaga tgtggaaaaa gaattatatg caaataaaat tcaagaactg
      361 gaagaaaaat taaaagaatt agaagttata cgtgaaaatg tattacaaag agaattaaat
      421 actagagccg gttatgtgta tgtaattagt aatattgggt cttttggtga agacatatat
      481 aaaattggta tgactagaag attagaacct atggatagaa taaaagaatt gagtagtgca
      541 tcggttccat ttgaatttga cgttcatgcg atgatttttt cagaggacgc tccgtctttg
      601 gaaactaaat tgcataatca ttttagaaaa caagaagtta ataaaattaa tcaaagaaaa
      661 gaatttttca aagtttcact agacgaaata gagaaagttg ttttagaaaa ttataatgga
      721 acagtaacat ttacaaaatt agctaaagct gaacaatata gacgatcttt agaattgtca
      781 aaagattaaa tatataaaaa gccttcgggc tttttctttt aacaattaat aggaacgtat
      841 attcgaaagg aatagaaata atgtggttag aaaaaataaa tgacaaaaaa tttaagtaca
      901 ccgaacgtta tacggatccc ttaactgaaa aaaagagaaa agtgtccgtt actttatcta
      961 gcaattcacg ccaagcttgg aatcaagcta acttactttt gaatgaaaaa atcgcagaaa
     1021 aaataaaacg aaatgaagaa ttaccactaa cttttggaga attaaaaact aaatgggatg
     1081 aaaaatacaa gccaactgta aaagaaagtt cctatcgaac aactcaggtt tatctatcat
     1141 taatttcaaa atatataaaa gatgatgtac ttgtaaaaaa cgttaatagt aatcttatac
     1201 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
     1261 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
     1321 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
     1381 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
     1441 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
     1501 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
     1561 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
     1621 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
     1681 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
     1741 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaaccta gataaaaaag
     1801 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
     1861 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
     1921 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
     1981 aaattgcccc ttttctgccc cttataaaaa caaacaacat aaaatatata aaaagaaccc
     2041 cgttataacg aggttctttt aatttaactt tcaaatacaa attgattatg ataaagttcc
     2101 gcataaaatc cattttctgc taataactca tgatgactgc cttcttcaat gacttcccca
     2161 tcacgcaaga caacgattct atctgcattc aagattgttt tcagccggtg agcaatcaca
     2221 aagctggttc ttcctttgat tgcttcatcc attgcttttt ggatccttgc ttctgttacc
     2281 gtgtctacat tacttgttgc ttcatccaaa atcaataaag atggatttgt gatgatcgtt
     2341 cgagcaatac tgatcaactg cttttgacct gtactgaata agttattttc ttcggatatc
     2401 tctgtatcat aacctttttc taacgtcatg atgaagtcat gaatattcgc ttgttttgct
     2461 gcattgatga cttcttcatc tgaagcgtcc ggtttgccga atgtgatatt gtctttgatc
     2521 gttccggaga acaatacaga ttcttgcaaa acgattccta catgtctacg taatgcatca
     2581 agatcataat ctcggatatc tattccatcg atgactactg aaccatcatt gacatcgtaa
     2641 aaacggttta gcagattcat gatcgtcgtt ttccccgatc ctgttggacc aacaagagca
     2701 accatttctc ctttgtccac attgatcgag acatctttca agactagttt ttctggagaa
     2761 taaccaaaat ctacgtgctg caacgcaaga cctttttcaa caccatcaaa tgctttaccg
     2821 ttttctggtt tgacttcatc tttttcatca aatatttcat tcaatcgtct tgcccctgta
     2881 atcgctaatt ggatcatgct gtatccagat gaaatctgca tcagtggttg gtaatattgt
     2941 tgtgaatact ggacgaatgt cacaactaag cctaatgcca ccgaacgttc caaatcacca
     3001 tttaatgcta accagccgcc gaaaaagata actatcgctg tattgaccag tgacattcct
     3061 tgcatcatcg gaaatagtag accagaataa gcttgtcctt tgaaggttgc ttcgcgaaca
     3121 ctttgattat gctctaagaa tccttcaatc gtttcttctt gtaagccatt tgtgatgatg
     3181 acacgttgtc cgctgatttt ttcatccata taaccattta gtttccccac ttcatcttgc
     3241 tgaagatcca catatttccg tgctttgcgg ataatcaaga cagctatcaa aacggctact
     3301 ggagtggaag caattgtagc ccaagctaac tctacatttt ggcggaacat catgatcaag
     3361 atcccgacaa gtaaaacagc attcgtgatg acttgaagca aagcttggtt caaactattt
     3421 tgaatattat ctaagtcact ggtaaaacga cttaaaattt caccgtcttg atgagaatca
     3481 aagaaacgga tcgtcaattt ttccaatttg ttgaatagac cgatacgcat tcggttcgtt
     3541 gacttcccta ctacttgtgt gaacaaaata ctatagataa agttggctgc actagctagt
     3601 acataaaaca gcaagagttt ccatattaca gaaacaaatt tgcttttatc gtctacgcct
     3661 tgcatcaagc ctcctacgta attagctaat tcttgaaaag cttccccgat gtattgaggt
     3721 gcctttactt gtagataggt agcaatgatc actgtgataa agataaagaa aaaggagagt
     3781 ttgtaccgct tcaaatagtg atagaaaaat ttacttgctt ttattagatc agtcatactt
     3841 actcctccgt tcctttttga gtttcaaaga tttcctgata gacacggttt ccagctacca
     3901 attcctcatg ggttccttcg ccgactaatc tgccttcatc caatactaag atgcggtctg
     3961 ctttgacaac agaagcaatt ttttgtgcga tgacaatcgt cgttgttccc ttcaaatctc
     4021 gatcgagtgc ttctcggacc agcttttcag agcgagcatc cagtgcactc gtactgtcat
     4081 ctaggatcaa gatctttgga ttaccgataa cgccacgagt aatggataaa cgttgctttt
     4141 gaccaccaga aaagttactg ctacgttctt ctattggtgc ttcgtaacga tcagataact
     4201 tttcgatgaa ttcttttgct tgagcaatag aagaagcatg ttccatctct ttttctgttg
     4261 cattcttttt cccttggcgc aagttttgag caatcgttcc tgagaataaa attgcttttt
     4321 gcaaaacaaa ggaaaccgtt tgtcttaaac tcttttcatt tacttgacga agatctacac
     4381 cacctacttc aactttgcct tctgtcggat caaatagacg agggatcaat tgtgctagtg
     4441 ttgacttccc ggcaccagtc gccccgacga taccaaccat ttctccaggt ttgatagaaa
     4501 agctgatatc tttaagcgta tctgtatcct caccaggata acgaaaagaa acatggtcaa
     4561 aagtgacaga acccgtcaac tcttgttctg gaacgtctaa ataagtaaga tctggttcag
     4621 catctaaaat ttccgcaatc cgcttcagcg atacggctgc tcttgaagtc atcatcatca
     4681 tcattccgcc aataatgatt gccatcataa tctgcatcaa gtagttcatg aatgaagcaa
     4741 ttccaccaat taacgtagga tcatctttaa caagatcgct cacaaaaaag atcgccccaa
     4801 ccacagccaa attggcagcc agcatgaagg acgggatcat cacagaaaat aatgtaccga
     4861 ctatgatgtt gtgttttgtt aagtcctcac ttactttgct gaatgacttc aattggtttt
     4921 cttcttgtac aaaagatttc actacacgaa tccctagtaa gttttctttt gcaatgctat
     4981 tcacacgatc aatcagtttt tgaatgatca tgaagtgctt gcccatcctt gtaaatgaaa
     5041 gtgccgtaat cagaaatacc gtaacgataa gcgctacgat gatccaccat aattgcggca
     5101 tcgtgatcat agctaaaatg aaggcaccaa taaataagaa tggaattcga aaaagtgatt
     5161 gcaaagaaat catcactaaa ttttggattt gcgtgatatc atttgttaga cgaacaacaa
     5221 gatttccagc agagaactgt tcgatatttc caaatgaaaa tgtctggatc tttcgaaatg
     5281 cttcttctcg gatatctgca cttacgcctt gagctacttt tgcagagaaa atcgtgttcg
     5341 ttacacctgc ggctaatcct agcaaagcca gactgatcag gtaaatacca attgttttca
     5401 tttcatcatt atcttctgta ataatagctt ccaatacttg ctgtagtaac ttaggttgcc
     5461 ataatgctgc tgcaaccatg actgctacgg acagcaagga aataaaaaca gatactttat
     5521 attttttcgc atgtcgtaag attaatttca ttcgttgatt acaccccttt gtttaaattg
     5581 acaggactaa tttaacactg taaaattaga ccgactaaca atttaccatg tttaaaaaga
     5641 taatgcaata cacgaggttg ataaaatgga aataaagctt tctcaagcaa tcatcattca
     5701 ggccgccttt gatatcctgg ctgaaacaca agctctttcg cagctttcca tgcgaaacat
     5761 cgcaaacaga attcatgttc aagcacctgc tttatattgg tatttcaaaa acaaacaaca
     5821 gctcttgcaa aaaatggctg aaacaatgga agaagaatta gcgcttccag atccaacttt
     5881 gccttggaat gaacagttgc tgcagtatat ggaaaattac tatgaccttt atacacgttt
     5941 cccttgtggg gcagaattag aaatcaatac tgtgcccgct tttccgagtc gattagaaca
     6001 tttggagcaa atgatccaat tacttgttcg tgaaggattt tcagtcaccc aaagtcatca
     6061 ggccattgcc tctctccaca atttattgat tggacagtta atggatcagc agcatgaaca
     6121 gcagcttcga caaaaaatta tggacggaaa tgaatttttg aaagaaacag ttctatttat
     6181 gcgtaattat gtagttgaaa atcaattaga gggatttaaa gaaagtatgc agtcccatgc
     6241 agaattgaat gaaaaagcac tctttctaac gagtgcacaa acctatattg aaggcttatg
     6301 ccaacaaaat aaaagaagag aaaacgagca gtaaaaaagc tcctatagag atcactatgt
     6361 ttgtgatctc tataggagct atctttttaa gactcttttt ttatttttct tccattagcc
     6421 acgccaatgc acgttgaatc cattggtccc agaagatcca gttatgatcg ccaggtcctt
     6481 gttcaaaggt gaccgccaag ccttgttcct gcatagcaga taccatttcc tgatttgcct
     6541 gataaagaaa atcagattcc ccacaagcca tataaaatct tggaactggt tttccgcttt
     6601 ttactagttc tttcaataag tattgcggat cattttttga accttcgatt tgatccaatg
     6661 gtccaaagat cccttcccaa aaagatgctt tacgaaccat caaaagatca tccattcgat
     6721 ttcctacaga aacagcgcct gaaagagaga ttactgctgc gaaattttct gattttgcaa
     6781 ggcctagttt taacgcgcca tatccgccca tcgataatcc agcggcatat gttttttctc
     6841 tttttcttgt taattgcggg aataattcat gacaaatctc aggtagctct tctgcaatga
     6901 atgtccaata cttcatgtca taaactgtat ctgtgtacca gccaagatca gtagatggca
     6961 tgatgacagc taatccgtag tttgctacat aacgttcaat cgacgtacgt ctttcccata
     7021 cactatgatt gccacccatt ccatgaagta aatataaaac aggtatatcc gttgtctctt
     7081 gctctgaact ggtgccaatc accttttttg ttgtttgcgg tagtatcaca tttagattga
     7141 cttccatttc taacacattc gaataaatat ttgcttgaat aaatgccata ttttcgcctt
     7201 ccttagtaag aagttatttt tgaataactt taaatttgaa tgattcggct acgtacatat
     7261 cttaaccgaa actactgttt tattttacca cttttttcat gaacgaaaag cgttaagacc
     7321 aaagcaatga tcacgagtaa caagccaact agataaacgg aatgtaaccc atcataaaga
     7381 atttttctta atggtaacaa aatatccgca tcaatatatt tagccgtttg tggattcacc
     7441 agtttattca tgatatctgc atcatttgtt aaatttgctg ctgcaagttc tcgtttagtt
     7501 accccattta tcaataaacc aaaaatagaa accatgactg tttgaccaat tgttcgaact
     7561 aacgtattaa aagaagttgc tacaccaagc tggtcacgag atacactatt ttgtgcactg
     7621 acagtcgagg tagtcatggt cacacctaag cctataccga tgaccgttga tatagcaaaa
     7681 aaccataaat agttacttct gaaaggcata agatacaacc aagcgccccc aatagctgcg
     7741 attagtagtc caattctcaa gacccaatga gttttcattt gagtcatcca cttgcttgca
     7801 aggaaagaac cgaccatcca gactagtgat aatggtgcta ataccagccc accaattgct
     7861 gcattcagcc ctaatacacc ttgcatccac atagggatat aaacatcgat tcccatcaaa
     7921 aaaccactag ccaatgctgc agccaagttg accacaacaa atagtggatt tttgaataaa
     7981 tgcatcatga tgacaggatc tttagctctt ttttcggcaa aaacaaaaat acctaacatt
     8041 acgatactac ctagcagcaa agcagaaaca agcggactca ttccttcgtc tcctaataat
     8101 tggaacccta acagcaatga gacaagcatg gccatcaaac taaaactacc aaaaatatcc
     8161 attggtttag actcatgtat gatttttggt tcatttaaat atagccaaat caaaataatt
     8221 aatagaattc cgatcggcac attgataaaa aagatccagt gccagctgat cgtttcaacg
     8281 atgaatcctc ccgcaagcgg tccaaaaaca ctggcaatcc cccaggctga actattcaaa
     8341 cctaaaactt ttgctcgctt ttcaatagaa taaagatcgc cgatgatcgt caaagctact
     8401 ggcatcattg ccccagcacc catcccttga atcgcacgag cagcaatcaa cccaatcatg
     8461 ctttgagata aaccgcaaaa taacgaaccg ataataaaca ataatgtccc aaaaataaag
     8521 attggtttcc gtcccacttt atccgcaagt tttccgtaaa tcggagtaag catagcgttt
     8581 gtcagcaaat aaatcgaaaa tacccagttc atgatttcca ttccatgtaa tgaaccgaca
     8641 atcgttggca tagcggttgt tacgattgta ccttcaatag ccgtcatgaa cgttgcaatg
     8701 aaaatactca ctgtgaccaa agtaacattt gtttcttttt tcatcttatt cctccctttc
     8761 attatgacag gatctaaaaa tagataaata attactatct ttttcaagag gttaactgcc
     8821 ataaaaaaag ctggaacaac caccacttgg cgatcgttcc agctgaatat aacttatttt
     8881 gctaaacttg ctttcaacgc atctactttg tccgtatgtt cccaaggcaa atctacatct
     8941 gtacgaccaa aatgaccgta agcagctgtt tgtttgtaaa tcggacgacg caaatcaagc
     9001 atctcgatga ttcctgctgg ccgaagatcg aagttttctc tcactgcagc aatcagttct
     9061 tcttccggaa ccgttccagt accgaaagta ttgattgaga tcgaaacagg ttgagcaaca
     9121 ccaatcgcat aagctagctg tacttctgct ttgcgagcaa gccctgctgc aacaatgttt
     9181 ttagcaatat aacgtgcagc atagctggca gaacggtcaa cttttgtcgc atctttacca
     9241 gaaaaagcac cgccaccatg acgagcataa ccgccatacg tatcaacaat gatttttctt
     9301 cctgttaatc cggcatcccc ttgaggacca ccaatgacaa atcggccagt cggattgata
     9361 taatatttcg tttgatcatc taataattca gctggaataa cttccttcac tactttttcg
     9421 atgacatcat gacgaattgt ttcattatct actgcatcat catgctgtgt tgaaataacg
     9481 attgtatcta cgcgttccgg ttgtccttga tcatcatatt caaccgttac ttgagatttt
     9541 gcatctggac gtaaatacgt taattcattt gatttacgca aatctgccaa gcgtcgtacc
     9601 agacgatgac tcaaagcgat tggtaaaggc atcaattctg gtgtttcatc tacagcaaac
     9661 ccaaacatta aaccttggtc accagcacca atctcatcta atacgtcttt tttatcttca
     9721 tcccggatct caagtgcttc atcaactcct tgagcaatat caggagattg ttcatcaatc
     9781 gcaaccaata cagctgctgt atctccatca aatccgaatt ttgcacgtgt ataaccaatt
     9841 tcttttattg tttcccgtac gactttttga atatctacat atgccgtcgt agatatttct
     9901 ccaaatacta aaacaagacc agttgttaca gacgtttcac acgctactcg tgctgttgga
     9961 tcttgtttta aaattgcatc caagattgca tcactgattt ggtcagcaat tttatctgga
    10021 tgtccttcag aaacagattc tgatgtaaat aagtgtcttt ctaccattat aatgattccc
    10081 cctagttaaa ttcggttaca aggcatctcc gtcctgcgga tcctttcggg aacttgcaac
    10141 gaaccaagta tagcagataa aacagttttc tgctcgtatt ttttcatttt tttgcttaaa
    10201 aaatataaaa atattttaca ttagaactgt ccaaaaaagc ttagcacaat catccataaa
    10261 gataactctg ctaagctttt taaaatcatt ctttcagata aaaagaaaaa gatactcaaa
    10321 aagtatcttc catgacccgt acgggattcg aacccgtgtt accgccgtga aagggcggtg
    10381 tcttaaccgc ttgaccaacg ggccaataaa ataaatgggc ctaaatggac tcgaaccatc
    10441 gacctcacgc ttatcaggcg tgcgctctaa ccagctgagc tataggccca taaaaactaa
    10501 aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt tttaccacta
    10561 aactacaccc gcataatggc gcgggacaga atcgaactgc cgacacatgg agcttcaatc
    10621 cattgctcta ccaactgagc taccgagcca aacggttccg acgggaatcg aacccgcgat
    10681 ctcctgcgtg acaggcaggc atgttaaccc ctacaccacg gaaccaatgt ttttagtttt
    10741 taattgcggg agcaggattt gaacctacga ccttcgggtt atgagcccga cgagctacca
    10801 gactgctcca tcccgcgata atatgaaaaa ggaggataag ggattcgaac ccttgcacgg
    10861 ttttacccgc ctgacggttt tcaagaccgt tcccttcagc cggacttggg taatcctcca
    10921 tgtaaaacta tattaaatta atgacccgta cgggattcga acccgtgtta ccgccgtgaa
    10981 agggcggtgt cttaaccgct tgaccaacgg gccaggtaaa acaaaatatt gaaacggaga
    11041 aggagggatt tgaaccctcg cgccggtttc ccgacctaca cccttagcag gggcgcctct
    11101 tcagccactt gagtacttcc ccaaaaccaa taagattttg tactaatggg cctaaatgga
    11161 ctcgaaccat cgacctcacg cttatcaggc gtgcgctcta accagctgag ctataggccc
    11221 ataaaaaact aaaagcgggt gacgagaatc gaactcgcga caacagcttg gaaggctgtg
    11281 gttttaccac taaactacac ccgcatggcg gttccgacgg gaatcgaacc cgcgatctcc
    11341 tgcgtgacag gcaggcatgt taacccctac accacggaac cagtgttttt agtttttaat
    11401 tgcgggagca ggatttgaac ctacgacctt cgggttatga gcccgacgag ctaccagact
    11461 gctccatccc gcgataatat gaaaaaggag gataagggat tcgaaccctt gcacggtttt
    11521 acccgcctga cggttttcaa gaccgttccc ttcagccgga cttgggtaat cctccatatg
    11581 aaacttacaa cgccacaatg gaccttgtag gactcgaacc tacgaccgga cggttatgag
    11641 ccgtctgctc taaccaactg agctaaaggt ccaggctctt aaaaatcgcg gcggagggga
    11701 tcgaaccccc gacctcccgg gtatgaaccg gacgctctag ccagctgagc tacaccgcga
    11761 aaaagatatt cattatttaa atgaaatgga gcctagcggg atcgaaccgc tgacctcctg
    11821 cgtgcaaagc aggcgctctc ccagctgagc taaggccccg tgtttaaatt tataattatc
    11881 gggaagacag gattcgaacc tgcgacccct tggtcccaaa ccaagtgctc taccaagctg
    11941 agctacttcc cgtttaatta acgcgcccaa gaggagtcga acccctaacc ttttgatccg
    12001 tagtcaaaca ctctatccag ttgagctatg ggcgcatatt tgaaatgccg aggaccggaa
    12061 tcgaaccggt acggtgatca ctcaccgcag gattttaagt cctgtgcgtc tgccagttcc
    12121 gccaccccgg cgcgattgct ttggcaaagc ggaaaacggg gttcgaaccc gcgaccccca
    12181 ccttggcaag gtggtgctct accactgagc tatttccgcg tgtttaaaga tgccggctaa
    12241 aggacttgaa ccctcgaccc tctgattaca aatcagatgc tctaccaact gagctaagcc
    12301 ggcatgtaaa acttaaatta tgcgggtgaa gggacttgaa cccccacgcc gtaaggcgct
    12361 agatcctaaa tctagtgcgt ctgccaattc cgccacaccc gcaaaaatat gagccgtaca
    12421 gggctcgaac ctgtgaccct ctgattaaaa gtcagatgct ctaccaactg agctaacggc
    12481 tcatatggag gttaacggga tcgaaccgct gaccctctgc ttgtaaggca gatgctctcc
    12541 cagctgagct aaacctccat ggataactt
//
LOCUS       DADGHT010000087        12527 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.088, whole genome shotgun sequence.
ACCESSION   DADGHT010000087 DADGHT010000000
VERSION     DADGHT010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.088"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(78..2198)
                     /locus_tag="JX887_002220"
     CDS             complement(78..2198)
                     /locus_tag="JX887_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAX1258163.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2428..3606
                     /locus_tag="JX887_002221"
     CDS             2428..3606
                     /locus_tag="JX887_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAX1258164.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3622..4380
                     /gene="aroD"
                     /locus_tag="JX887_002222"
     CDS             3622..4380
                     /gene="aroD"
                     /locus_tag="JX887_002222"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAX1258165.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4403..4888
                     /gene="ybaK"
                     /locus_tag="JX887_002223"
     CDS             4403..4888
                     /gene="ybaK"
                     /locus_tag="JX887_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAX1258166.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4959..6212)
                     /locus_tag="JX887_002224"
     CDS             complement(4959..6212)
                     /locus_tag="JX887_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAX1258167.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6328..7677
                     /gene="gdhA"
                     /locus_tag="JX887_002225"
     CDS             6328..7677
                     /gene="gdhA"
                     /locus_tag="JX887_002225"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAX1258168.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7789..9135
                     /locus_tag="JX887_002226"
     CDS             7789..9135
                     /locus_tag="JX887_002226"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAX1258169.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9443..9829)
                     /locus_tag="JX887_002227"
     CDS             complement(9443..9829)
                     /locus_tag="JX887_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAX1258170.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            10708..10920
                     /locus_tag="JX887_002228"
     CDS             10708..10920
                     /locus_tag="JX887_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258171.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11198..>12527)
                     /locus_tag="JX887_002229"
     CDS             complement(11198..>12527)
                     /locus_tag="JX887_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAX1258172.1"
                     /translation="FIMDFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRS
                     FRAAIRESWSLTKSRLLAITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALI
                     SAVFAMTLLQGILLFNIVMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALK
                     NTGLTLFAVFFGIGVCLYNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRD
                     YHPDYVEMDVQETKDGHFVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPV
                     CSFDSYLEKAHKLNQKLLIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTV
                     SDLKEAEPNFYVGYILPFNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTI
                     NDSDAMSRMMFYGVDGIITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4073 a         2258 c         2480 g         3716 t
ORIGIN      
        1 tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctaatttt gtcgctgctc
       61 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
      121 gtttgcgttt tataaagatc aacagttgat tgtcccttgt gttcactaaa gacactagtt
      181 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
      241 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
      301 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
      361 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
      421 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
      481 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
      541 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
      601 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
      661 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
      721 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
      781 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
      841 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
      901 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
      961 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     1021 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     1081 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     1141 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     1201 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     1261 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     1321 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt caagctggag accattctca
     1381 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     1441 ttttttcctt tagcgagccc gaacaaatca tcatttggtg ctgcataatg ttcttttaca
     1501 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     1561 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     1621 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     1681 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     1741 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     1801 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     1861 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     1921 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     1981 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     2041 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     2101 aaataggcaa aaatcgtttt caaccaaagt aaaacaacta gtaaagaaaa aaatccgagc
     2161 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     2221 cttaatcaca gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta
     2281 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     2341 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     2401 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     2461 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     2521 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     2581 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     2641 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     2701 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     2761 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     2821 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag
     2881 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     2941 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     3001 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     3061 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     3121 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     3181 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     3241 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     3301 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     3361 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     3421 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     3481 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     3541 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     3601 cattagaagg agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga
     3661 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     3721 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     3781 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     3841 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     3901 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
     3961 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
     4021 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
     4081 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
     4141 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
     4201 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc
     4261 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
     4321 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
     4381 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
     4441 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
     4501 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcata tatttaaaac
     4561 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
     4621 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
     4681 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
     4741 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
     4801 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
     4861 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
     4921 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
     4981 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
     5041 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
     5101 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
     5161 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
     5221 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
     5281 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
     5341 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
     5401 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
     5461 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
     5521 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
     5581 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
     5641 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
     5701 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
     5761 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
     5821 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
     5881 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
     5941 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
     6001 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
     6061 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
     6121 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
     6181 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
     6241 tctgaagaaa gaaaacagaa aaaatgtttt gagccaaaag agaaaatgag ctaaaatgag
     6301 ggaagataag caaaggagcg tggaacgatg acaaacgcaa cagaatatgt tcaagcaatt
     6361 caagaaaagc tacatcaaaa ggatcaaggg caagaagaat ttttacaagc aatcgatgaa
     6421 ttcatgccca cggttatgtc ttttttggac actcatcccg aatatatcga aaagaatatc
     6481 ttagaacttt taacggaacc agaaagagtt attcaatttc gagtgccttg gcaagatgat
     6541 gaaggaaact ggcgagtaaa tagagggtac cgtatccaat acaactcagc tatcggccct
     6601 tataaaggtg gattgcgctt ccatcctagt gtcaatctaa gtatcttgaa atttttggct
     6661 tttgaacaga ttttcaagaa tagtttaacc ggtctgccaa tcggtggagg aaaaggcgga
     6721 agtgacttcg atcctaaagg aaaatctgat aatgagatca tgcgtttttg tcaaagtttc
     6781 atgctggaat tgtcaaaaca tatcggccca tcgattgatg ttcctgcggg agatatcggt
     6841 gtaggagcta gagaaatcgg ctatttgttc ggcgaatata aacgattgaa aaaatatgat
     6901 actggtgtgt tgacaggtaa acctttggat ttttggggaa gtaagatacg tacggaagct
     6961 actggttatg gattagtgta ttatgtcaaa catctattga acgaagaaaa agattcattt
     7021 aatcaaaaaa cagtttttgt ttccggaagc gggaatgtag ccatttatgc aatcgaaaaa
     7081 gtgcaagagc taggcgggaa agttgttaca tgttcagatt ctagcgggta catctatgat
     7141 ccagaaggaa tagatgtgaa actattgaaa gaagtcaaag aaatcaatag acaacgtttg
     7201 acggaatacg caaaccaacg tccttctgct atttatcatg ctggagaatc tgtttggaca
     7261 ttgaaagaaa aagcggatat cgctttgcca tgtgctactc aaaatgaaat agacgaaagc
     7321 ttggccgaaa tcttagtaga aaatgggatc aaaatcgtag cagaaggcgc taatatgcca
     7381 tgtacagtaa aagctgtttc tgttcttcat gaagcaggcg tgtggtattg tccaggaaaa
     7441 gctgctaatg ctggaggagt agcagtatct gctttagaaa tgagtcagaa cgcccagcga
     7501 ttgacttggg aaagagagca agtggatgag cagctggatc aaatcatgga aacgatttac
     7561 catacgtgtc gccaaacagc agccgagtac ggcgacgaaa aaaatctgct tcttggagca
     7621 aatgttgctg gatttgaaaa agttgccaaa gcaatggcag cagaaggttt agtttgaaaa
     7681 atgaaacttt cttggaaata ttgtcagcat tttgtttatt tgcttgaaaa ataataaaaa
     7741 aaaacgtaaa gtattacctg tagagtaaac ctataaggag gagaacaaat ggcacacatt
     7801 cattttgact attcaaaagt agcaccgttt gtcaacgaac aagagttagg gtacatgcaa
     7861 agccaagtaa cagcagccca caacgaatta cgggaaggta ctggcgcagg aagcgacttc
     7921 cgcggctgga tcgatttacc aacgaactat gacaaagaag aatttgcacg tatcaaagaa
     7981 gcagctaaaa aaatccaatc tgattctgaa gtattagttg ttatcggtat cggtggttct
     8041 tatttaggcg ctcgtgcagc gatcgacttc ttgaatcaca cattcttcaa tttattagat
     8101 agcaacacaa gaaaagcacc acaaatcttc tttgccggaa attcaatcag ctcaacatat
     8161 attgctgact tgatcgaagt aatcggtgat cgcgactttt cagtaaacgt tatttcaaaa
     8221 tctggaacaa ctactgaacc agcgattgcg ttccgtgtat tcaaagagct tcttgttaag
     8281 aaatatggac aagaagaagc aaacaaacgt atctacgcta caacagataa agcaaaaggt
     8341 gcagttaaag tagaagcaga tgcagaaggt tgggaaactt tcgtgattcc tgatgacatc
     8401 ggcggacgtt tctctgtatt aactgctgtt ggtttgttac caatcgctgt tagtggtgca
     8461 gatatcgatg cattgatgca aggtgccgct gatgcaagca aagcatactc aagcgacaaa
     8521 ctagaagaaa acgaagctta ccaatacgca gcaatgcgca acattcttta ccgtaaaggc
     8581 aaagtaactg agttgttgat caactatgaa ccaggaatgc aatacttctc agaatggtgg
     8641 aaacaattgt atggtgaatc tgaaggaaaa gaccaaaaag gcatctatcc ttcaagcgca
     8701 aacttctcaa ctgatttgca ctctttagga caattcatcc aagaaggacg tcgcaatatt
     8761 tttgaaacag ttgtgaaggt tgaaaaacct cgtaaatcaa tcacaattcc tgaacaagca
     8821 gaagatttag acggtctagg ctacttgcaa ggaaaagaag tggacttcgt aaatacaaaa
     8881 gcatttgaag gaacattgct tgctcataca gacggtgacg tgcctaactt gctagtcaaa
     8941 attccagaaa tggatgctta tacattgggt tatacaatgt acttctttga aattgctgta
     9001 ggtatttcag gttacttgaa tggaatcaac ccattcgacc aaccaggtgt agaagcttac
     9061 aagaaaaaca tgttcgcact tctaggcaaa ccgggctttg aagatcttgc taaagaattg
     9121 aacgaacgcc tgtaagataa gggtttttcg ctagatttaa ataatcagtg atagaaacat
     9181 gttcgcttta aaatgaaaac tggtacccat ttaggtactc aaacatactg catcgtttat
     9241 tcagaataag gggctgtgac aagacgtttg tcacagtccc ttgtttgtat agaaatcgat
     9301 tgattgcctt gctctttagt ttgttttagg actttaagaa cagtgaggct gacttcgaag
     9361 gttaattctg tttttttgtt ttctagaatc agtaagcaaa aaagcactca cttcgagtgc
     9421 ttttttgcga tatattctta gcttaagata ggcctaattt ttcttttaca gatgagggta
     9481 ccttatcgct ggtaattact tttttctcta tgatccgctt ttcgcttgct ttcaactgca
     9541 agatcgttcc ttcggtgtaa gcagaaccat tggcagagtc accagaagta atgacatcga
     9601 aatctaactg tcttttttca ccgttttcag cataagcatc tacgttgtat ttaaaacctc
     9661 ttccaattac ttccccatta tctgctttga tatcagtttc tgcaggcatt ggagctttga
     9721 ctaccgcata ataatcttta cctacataag tagactgata gtagtcccaa cctttccatc
     9781 ctataaaagc aatcaatatg ataacgatca accctaaaat ttttttcatg aaagatctcc
     9841 ttttttattt ttattatatt aaatattata cagataataa cggaatatta tcatcgaaac
     9901 agctaacaaa attgtcataa aaaacgagat ggttgatatt agaacttgtg tttttgttta
     9961 ggtctagaga taaagagaga caatttccaa atatatgtaa tgaatacaaa aagacgtttg
    10021 tcgcggatta ccgttacaaa cgtcttttat tgattttccg agatctcatc agtcgccatt
    10081 tggaatggtt cactccttat ctagattcgt ttaatgctcg gactgcttgt tcgattgtaa
    10141 taccaaacgc aacgttattt tcgttttgtg catcaatcgc cataaaacgg ttagaagttg
    10201 tatcaaaagc tacgcggtat tgcatatttg tttttgtaaa cgtcataaaa ttcatctcct
    10261 ttgtaatgta atttagttct tgaaagtttc ctttaaactt tcgaacttat accaagttta
    10321 gcatcgtacg ttttttgatg caattaaaaa gcatttatca ttttccttat ttattttttc
    10381 ttaaatggtt tagctatttt cttttaatcc gataagtagc ccaatcatca aggttacaaa
    10441 tactattgct tgaatataaa tcatatgctc acctctttat aaataactta gcaatataaa
    10501 gaaaaaaacg cacgaacaac ataggaatat aaacaaacgt ttttgtcaca acgtctaaga
    10561 tcgtgttaaa aaatagttat ctaaaaagca gaaagatact caaaataaaa aataaaaaaa
    10621 tgaataaaaa cgttttcaaa tacaaggtaa tttgttatta taaaataaag aaaaaacaaa
    10681 ataaaaataa agaaaagagg gaatgaaatg gtaaaagcag aagtaggaag atcttatata
    10741 tgcaaaccga tcggagtatc tcatgaacta atcggctgta ttgaacgtac atatatcaac
    10801 acggctgtcg tgtatgttga aagttatgac caacgagact atcaacttat caatgaaagc
    10861 aagtatcgca tgctcgtaaa attctgtgat attagcgcac ctactgaatt ggtttcttaa
    10921 acagtatttt tgagaattcg caagaactcc cttataatat aaataaagac agaagggagc
    10981 gagaagatat gccaaaaaga aaaagttcag ggaaaatggg aattattctt gcagtgatct
    11041 ctgcaattcc tgctatttta gctattgttc gtgcgatgaa ggaatcaaga gaaagttaag
    11101 cacacattat gagcgtcaaa caaaaaacgc atatacctgc ggtggcaggt tatgcgtttt
    11161 ttgttgtata aagacttttt tcattaacga tttttgatta gccgactccc aaaacaaaat
    11221 ttagcagttt atctgaataa gtgatttctt catctgtttg tttcacactt tcatttagta
    11281 gtcccatctc atcggttatg ataccatcca caccataaaa catcatgcga ctcatggcat
    11341 ctgaatcgtt gattgtccat acatatactt cttttccgtc ttggtgggca gaattaatga
    11401 agttacggtt gatcgtacta tattccattg tcagaaaatc agcaggcgtc acagggggcc
    11461 caacaatatt gaaaggtaag atgtagccca cataaaagtt tggttctgct tcttttaaat
    11521 ctgaaacggt ttggtacgtc aaactttgca aaatatgatg gttctctaag ataactttgc
    11581 ggtatttatg gacaaatcgt tcgacaaggt catccgaatc ttttttagag gtcttgatct
    11641 caataagtaa tttttggttt agcttatgtg ctttttccaa ataagaatca aaagaacaaa
    11701 caggggcttg cactccgttt tcagtaactg taagatttgt caattctttc aatgtaagat
    11761 cctgtggtgt tccatttacc cctgttaagt gacgaagatt tgcatcatgc atcactacga
    11821 aatgaccatc ttttgtttcc tgaacatcca tctctacata atcaggatga tagtctctgc
    11881 ttgttttttc aagtgcttct aaagtatttt gcgccccatt ttgggtactc acacctctgt
    11941 gagagacagt cactggtttt gtctgaacag ctgaagtcag ataatccata ttgtaaagac
    12001 agacgccaat accgaaaaaa actgcaaaaa gagtcaaacc agtgtttttc agcgcagaga
    12061 aacgcaagtt gggggcttgt gggataaacc acttagggat ctcaggcaag aagccttcgt
    12121 catccatgaa atcaacaatg atataaaaaa tccctacggt agacatcacg atattgaata
    12181 ataaaatccc ttgtaaaagc gtcatagcaa acacagcgct gatcaatgca tagtctggga
    12241 aaaattgttc aaccatactt tgtgccaaaa taacaacgat atatcctaaa gaagaaagga
    12301 gtaaaatcgt accgccaatc acaataaatt ggcccgtgat ggccaaaaga cgcgatttgg
    12361 tcaatgacca gctttcccga atggctgctc gaaaagaacg atctcgtaga atcatttccg
    12421 gtaaagcaaa aatcagtcga atcccaatat agccaaggaa aatataaacg agtaaaaagg
    12481 aactgacgat gatccaacga ttagcaaaaa taaaatccat aatgaaa
//
LOCUS       DADGHT010000088        12442 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.089, whole genome shotgun sequence.
ACCESSION   DADGHT010000088 DADGHT010000000
VERSION     DADGHT010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.089"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(128..775)
                     /locus_tag="JX887_002230"
     CDS             complement(128..775)
                     /locus_tag="JX887_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HAX1258173.1"
                     /translation="MEQTIKPYQYFFIKREVDQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILEHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(1054..1557)
                     /locus_tag="JX887_002231"
     CDS             complement(1054..1557)
                     /locus_tag="JX887_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAX1258174.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(1680..2444)
                     /locus_tag="JX887_002232"
     CDS             complement(1680..2444)
                     /locus_tag="JX887_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAX1258175.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     NAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            2551..2826
                     /locus_tag="JX887_002233"
     CDS             2551..2826
                     /locus_tag="JX887_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAX1258176.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            3503..4453
                     /gene="yidC"
                     /locus_tag="JX887_002234"
     CDS             3503..4453
                     /gene="yidC"
                     /locus_tag="JX887_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAX1258177.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(4632..5606)
                     /gene="lacD"
                     /locus_tag="JX887_002235"
     CDS             complement(4632..5606)
                     /gene="lacD"
                     /locus_tag="JX887_002235"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAX1258178.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDTKIPGR
                     LPDLLNIWSVKRLKEAGADACKFLLYYDVDEPAEINVQKQIVIERIGSECEAEGIPFF
                     LEILSYDATIGDPSSLAYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QETCYSQAEASAYFYEQSKVTEQPFIFLSAGVNATLFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATPVYVDR"
     gene            complement(5603..6061)
                     /locus_tag="JX887_002236"
     CDS             complement(5603..6061)
                     /locus_tag="JX887_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAX1258179.1"
                     /translation="MTIIHEENIFLQQPLDSQEEAFKFLAKQTFCLGIALDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSMIIATLNKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRKAKSKTEIATILTKEIGEDL"
     gene            complement(6058..7521)
                     /locus_tag="JX887_002237"
     CDS             complement(6058..7521)
                     /locus_tag="JX887_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1258180.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGIKIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFAGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAMSGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSFDPDHAQYNATAAMVKAVGDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLTILPKQLDGLKAIFLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEHSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLAQGN
                     TTFMAGVSAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKMDNKAANRTVIEKGRAGDLS"
     gene            complement(7503..8453)
                     /gene="pfkB"
                     /locus_tag="JX887_002238"
     CDS             complement(7503..8453)
                     /gene="pfkB"
                     /locus_tag="JX887_002238"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAX1258181.1"
                     /translation="MSIYTCTMNLAIDLFIETEEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPKIPQTAVHNFLNQIRALQAEDYLCVSGSLPRGLSPKVLIEISRICQEKGI
                     HLIIDSSDQEAMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVELGAENV
                     LLSLGEKGAILFTKDRVFRGNSPKGKVVNTACAGDTMLGAFLAGYMNRRPLDETLRKS
                     IAAGSSTAFRKGLTDFLDVEELSKQIKIKEERFETWENIN"
     gene            8596..9345
                     /locus_tag="JX887_002239"
     CDS             8596..9345
                     /locus_tag="JX887_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAX1258182.1"
                     /translation="MDHKLSETEQYLWNFIEHHILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGETKELVTAAKNCYDAEIGSILVTANHSSTLKDYCEINLVGFKSEGS
                     YFPDYEVRSRLPLQIIARILLDAYVLRMGEN"
     gene            9612..11090
                     /locus_tag="JX887_002240"
     CDS             9612..11090
                     /locus_tag="JX887_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HAX1258183.1"
                     /translation="MKKLSQKRLAQIIIDSRKSLKMTQQQLAVATGINRALISRLESL
                     DFIPSIQQLESLAEVLNFEPTDLFINESNKSNRTKHQSKNIAVAGTGYVGLSIATLLA
                     QHNQVTAVDILPEKVKQINNKKSPIQDDYIEKYLAEKNLNLIATTDGAAAYREADFVV
                     IAAPTNYDSKQNYFDTSAVESVIKLVLEVNPKAIMVIKSTVPVGYTESIRKKYNTKNI
                     LFSPEFLRESKALYDNLYPSRIIVGTDQTDKTLREASHTFADLLQEGAIKKDIETLFM
                     GFTEAEAVKLFANTYLALRVSYFNELDTYAEMKGLNTQEIIHGVCLDPRIGTHYNNPS
                     FGYGGYCLPKDTKQLLTNYNDVPQNMISAIVDSNRTRKDFIADRVLELAGTYEANSSW
                     NAEKEKEVVIGVYRLTMKSNSDNFRQSSIQGVMKRIKAKGATIVIYEPTLENNTTFFG
                     SKVINNLDDFKNISHSIIANRYDSNLDDVKEKVYTRDLFQRD"
     gene            complement(11158..12249)
                     /locus_tag="JX887_002241"
     CDS             complement(11158..12249)
                     /locus_tag="JX887_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAX1258184.1"
                     /translation="MLELNTSLSNRTILITGAAGFIGSNLVLELLRTQSSIKIIGIDN
                     MNDYYDVSIKNYRLSEIETEAKNHPGSTWNFIKGSIADKATIDFIFDNYKPSIVVNLA
                     AQAGVRYSITNPDMYIESNIIGFYNILEACRHSYDNGESGVEHLVYASSSSVYGTNKK
                     IPYSTEDKVDNQVSLYAATKKSNESMAHAYSKLYNIPSTGLRFFTVYGPAGRPDMAYF
                     GFTDKLRAGDNIQIFNYGNCKRDFTYIDDIVEGVKRVMQCAPEKIDGEDGLPIPPYHI
                     YNIGNNTPENLLDFVDILQQELIAAGVLPEDYDFESHTELVPMQPGDVPVTYADTSAL
                     ERDFEFKPSTSLRDGLRKFAQWYKSFYEV"
BASE COUNT         3875 a         2526 c         2103 g         3938 t
ORIGIN      
        1 agaaaggggc tatccccaga ctttagtagg cgtcattagc tatctttcgt tagcatttaa
       61 aggcgaacac catcacctat tcacttccat taaaagatag catatttttc tgtaaaaaac
      121 aataaaatta tcgttctttc tttacacgtt cagcaaattc atagaaagga gccaatttcg
      181 ttaactgttg attacattgg tcactatcat gacaaatata attccccttt ttcgtatacg
      241 tgccatcaga acctgctttc gttgtagaaa gaaaaagcga cacattcgat gttttctgac
      301 agattgcaca gattccctta tttatcgttg gtgataaagt accgctaatc ccttttaatt
      361 tttcatcttc gtaatagacc atgaattttt tctgcgtacc tggatcattc cagccgatgt
      421 acgtatgttc ttgcaagtcg atttcattcc aagctggttg tttgagtttt ttcacttttc
      481 ggaataattt ctcgatttgt ggtttgctag gctgcataaa cggctggacg atttgcttca
      541 gctcctccaa tgctctttct gcttgcgctt ttgtcagttt tacgtctaaa actgtcgtta
      601 aaaatgtatc gatttctggc agttcgtgtt ctaatatgtc tcgaatcttt tcagctgcta
      661 gtgcctgaac tgtttgtacc gtttttggat cattgacaga tgagtacgca tttaataact
      721 gatctacttc tctttttata aaaaaatatt ggtatggttt tattgtttgt tccatgattt
      781 taaagtcctt tcttctaacc aaagtgcata ctttgtagaa aaaagtgatc ttctgcaaag
      841 tatgtgttac ctgaagatcc cggactcttt taaataagat acgttttgca tcttatcatc
      901 acccccttta atgttcattc ttctatgtac atgattcatt cgataaataa aagtaaaccg
      961 tatcttgaac agatagtcaa ctgcaaacag aaaaaaccga gaaaatcagc cagattttct
     1021 cggaatatag tctattatta ttggttttac ctattaaatc gaggattctt tcccaaagta
     1081 acgttgccat ctcttacgca tacttgcaga catgggctga gccgcttctt tgactgcgca
     1141 gtatttgtcc acgaatgtca caatatatcc ttctttatac ttaggcggtg cgatcgttgc
     1201 accccacatg tgcttcaaaa tgatatctcg ctcaagatcc gacaaatcgg tgattttttc
     1261 tgcattcttt acagcaattc ttggatggat atacgcatgt gtcccctcgt caaatttcgt
     1321 cgtacgccaa tcatagtaga acagatcatg caaaagtcca gcacgcgctg ttgctttagc
     1381 attgccaccc catttttttg cgagcagata actatagtaa gaaacactga tggaatgctc
     1441 caaacgagtg gaatgaacat gctgtgtgta attcgctaat tttttcactg cttctgtttc
     1501 taaaagatct tgtacataag acatatattc ttcgtcttca cgccattttt ctgtcataat
     1561 tatcgatctg ccaccttttt gaatttcatt ttcttctgaa attgatctaa gtataccacc
     1621 agtgttcgga ttattctagt cgctctagat aaaatagcta aagcttaata gttccttaat
     1681 cataaagaaa aatgataaag aacgatccct gctgcgactc cgacattcaa tgattccgca
     1741 tttcctttca ttgggatata tacgttctga tcagtcaaag acaagatttc ctgacttact
     1801 ccctgacctt cgtttcccat gattatagcg aaatcctctg ttttttctac tttgtctaat
     1861 gcatgtgctt cttcatttaa ttctgtaccg tacaccgtaa accctttgcc tttcattaca
     1921 gggattacat ctgccaaatc tttttgtaac acaggcaaat gataattgct tccctgcatg
     1981 cttcgcagca cctttgtact ataaatatct gccgttcctt tacctaataa aacaccagcc
     2041 ataccaaacg catctgccgt acggatcatc gttcccacat ttccaggatc ctgtacatta
     2101 tctagtaaaa gccagcctcc tgaaaaatct ggcgtatctt cagatgttaa cgtcatcact
     2161 gctaagatcc cttgcggtgt aggtagatct gacatagcgg tcatgacctc atctgaaact
     2221 agaaaagtag aaatctcttt gtttacagcc agccagtctc cccattcttt catacctctc
     2281 tgtgtcacaa aaagttcttt tatttctgca ttagacgacg cagcttcttc gatcagatgg
     2341 aacccttcca aaagatattc tgccttttct tctctgtatt tctttttatg tagttttttt
     2401 aattctttga ttcttggatt ttttgctgat tggatctctt tcacattcct cacctcaact
     2461 gattatatca tggaataggt gcttgagctt gtttcatcct aaaaaaatcg gtatcattga
     2521 tttataaaac aggaaagaaa ggtgacgaac atgcgcaaag ttaaaatgaa tgtccaagga
     2581 cgtgtccagg gcgtgggatt tcgctatatg accaagatgg ttgctgatca gttaggcgtg
     2641 accggaacgg taaaaaacga agacgacggc tcagtcacaa tcgaagcaat cggaaatgac
     2701 gacatcatcc aaaaatttat cgaagaagtc aagaagtctc cgagcccaag tggacgagtg
     2761 cagtatgtgg atgtccaaga agatccgatg attgaggaac gaaagaaatt tgatgtagtg
     2821 ggataaggtt gtgaaaaggt cgcttagttt tgagtattaa ggaaaatttt gtgaaaatgg
     2881 ctttccacat ttttgcataa atttgactta ataccgagaa actgactttt gaacaccgtc
     2941 gataaggttg tttttgaagc gctttgcctc gagtattaag gagaaacatt ttcaaaatag
     3001 cttctcatat tttgaaatgt aatgacttaa taccgagagg cagctgataa aacaccgtca
     3061 ataaggttgt gaaaaagctg gtctgcatca agcattaagg actggttgtg ataaatagct
     3121 ctccatattt ttcaacaggc tggacttaat gccgtagatg caagcttttg aacaccgtcg
     3181 ataaggttgt ttttgaggcg ctttgcctca agtattaaag acaggtagta aaaaagctga
     3241 tctataactt gcaatgaatt tgcttaaccc atattttcca gacagaacaa aaaagttttt
     3301 agttttttaa ataagaaaga aacacttgga atcactcttt tctttctaag tatttctttc
     3361 ttgatttttt gtcttttttc aaaatttttc gctacgaaaa agaacgaata tttatatgaa
     3421 atttctatga agttgattga attccatgcg cttttttagt atagttaagt ttgtgtaaaa
     3481 attatagaag aggaagtatt ctatgaataa atggaaaaac tggttattgg gatccggact
     3541 tgtcagtatc ctgctctttt tatctggctg tgtgcggatg gattcaaacg gaaaccctga
     3601 cacttcagga atcgtttatc gagtactcgt ccatcctatg ggccaagcga ttacatatct
     3661 agttgagaat ttcaattggt cttacggctg ggcagttatt gcaatgactg tgatcgttcg
     3721 tatcatcatc ttgccactag gtatcagtca atcgaaaaaa acaatgatcc aatctgaaaa
     3781 aatgcaagcg ttaaaaccac aagttgaagc agcacagcaa aagctaaaag ctgcaacaac
     3841 acgtgaagaa caaatggcag cacaagcaga aatgcagcaa gtatatcgcg aaaatggatt
     3901 gagtatgacc ggcggaatcg gctgtctgcc tctattgatc caaatgccga tcttctctgc
     3961 cttgtatttt acggcacgct acacagaagg tatccgggaa tcatcttttt acggcatcga
     4021 tctaggctca ccaagtatgg tgcttgtggc catcgcaggg gtcgcttatc tgcttcaagg
     4081 atatatttca acaatcggta ttcctgaaga acagaaaaag acgatgcgta cgatgctgat
     4141 cgtctctcct gctatgatcg tcttcatgtc aatcagtgcg ccagccggtg ttacacttta
     4201 ctgggtagtc ggtggtgtgt tcagctgtct gcaaacattc atcacaaacg ttatgatgaa
     4261 accacgtttg aaagcacaag tggcagaaga gttgaaacaa aacccgccaa aacaagtcgt
     4321 cactccaaga aaagacgtga cagaatcagc aaagccagct aacaacaaac aagcaacaaa
     4381 acaaatcaaa caaccaaaaa acagtacaaa caacaaaggc cgcaacgcag gaaagcagca
     4441 gaagcggaag tagatagtaa ataagagtgt aataaaaatt cattaacagt tttagcaatt
     4501 aaaaatatcg accaagattt ttgaaaaaga aatctggtcg atatttttat ttaagtgaat
     4561 gtttaatttg aatcatcgat tgatcgctat ctaattgcag cagcatcttt ttatgaagaa
     4621 acaacttttt cttatctatc aacgtagaca ggtgttgctg tttcttctaa tagtgtactt
     4681 aattctttaa tattttgttt tccttcttct aacatccaac tactcgcttt ttcttcgcct
     4741 tcggtaacaa aaggtgccac tcccttcgcc catgttgctc gcccacataa gacaccattg
     4801 aatgtcgaac ctgattgttt tgcaaaacgt aatgtatctt gaaatagcgt agcattgact
     4861 cccgcactta aaaaaataaa cggttgttca gtcactttcg attgttcata gaaatacgcg
     4921 gatgcctctg cttgactata acaagtctct tgcccatatc cttccacaaa tctcatattc
     4981 actggcactt ctactttcaa tacatccact tgataacgtt cttttgaaaa ttctcgcatg
     5041 gcttcaataa ctttatgtgg ttttactttt gcataggcaa gagaagacgg atcgccaata
     5101 gttgcatcat aagaaagaat ctctaaaaag aaaggtatgc cttctgcttc gcattctgaa
     5161 ccaatccgtt ctataactat ttgtttttgc acattaatct ctgctggttc atcaacgtca
     5221 tagtacaata aaaatttaca agcatccgca ccagcttctt ttaacctttt caccgaccaa
     5281 atattcaata aatcaggtaa tcttcccggt attttcgtat catagccggt tttttcataa
     5341 gctagcagta agccacattc tttctctcga agcgctgctg caggcaggcc gtattctgga
     5401 tcaagtaaaa tagctgaggc atagggagtc aggtattgag aaaccatctg tttaaattgg
     5461 atgatgtctt ctgatgtagc ttctttatat tggttgatca ttttcttcaa agcaccacgc
     5521 tggtcgattg ctaatgcgct aataattcca gcttcatccg tcaatcgctt caaacgttcc
     5581 tgtttttcta tactcatctt cttcatagat cttcacctat ttctttagtt aatattgtgg
     5641 ctatttctgt ttttgatttt gcttttctca actgttctgt aacctctttt cgcatcaatg
     5701 atcgtgcaac gagagacaat aatttcaaat gagtcgttcc tgcttctgaa tctggaataa
     5761 ataacgcaaa aataaaatca actgactgtc tatctaaact gttccattca attcctttgt
     5821 tcagtgtggc gataatcata ctaggttcgt tgattgtttg agacttcgca tgagggatag
     5881 caaaacctga cattattcct gtagtccctt ctttttctct ttctagaagt ttttgatata
     5941 cttctttttc gtcaagagcg atccctaaac agaatgtttg ctttgctaaa aacttaaatg
     6001 cttcttcttg actatccaat ggctgttgta aaaaaatgtt ctcttcatga atgattgtca
     6061 tgataagtct cctgctcttc ctttttcgat aactgtacga tttgctgctt tattatccat
     6121 cttcttgtct ttatcagtta ctcttttctt ttggattaat cctagtatca ctccaccaac
     6181 gatcgaacca ataagaatcg ctgtaaccca ttggattttt cccgtcacta caggtaacac
     6241 taaaaaacca ccatgtggtg ctggaacttg gacgccaaac aaataagtta agacagcagc
     6301 aattgatgag cctaacatca tcgtgggtaa cactcggatc gggtctttcg cagcaaacgg
     6361 aatagctcct tccgtaatat gagttgatcc taaaataaaa ttaaccaaac ctgcattacg
     6421 atcattggta tcaaaatatt taccaaacaa taaagtagca aaaccagtaa tcaacggtgg
     6481 tgcaatacaa gctgctgaca caccagccat aaaagtcgtg tttccttgtg ccaaaagagc
     6541 tgttcctgtt acatatgccg ccttattaac cggtcctccc atatcaaacg cacacataca
     6601 gccaacaatc acgccaagaa caagtggatt cgaatgttca aatccagcta aaaagctcat
     6661 cattccttca tttatagcct tcattggacc tgccagcaaa gacatcacga tgccaataaa
     6721 tgctacacca ataactggat ataagaagat tgccttcaag ccatctagtt gtttaggtaa
     6781 aattgtcagt agcttttgca aaaataagat aaaataacct gctaagaacc cagctaaaat
     6841 acctcctaaa aatccagtac cgccattcat ggctacgatt ccaccaacaa atccaacgac
     6901 taaccctgga cgtttcgcga tcccttctgc aatataagct gctaaaactg gaaccatcat
     6961 tcccattgct gcatcgccaa ctgcttttac cattgccgct gtagcattgt attgtgcatg
     7021 atctggatca aaagaataga ttccccaaac ggcaaatgaa atagcaatca atactccgcc
     7081 agctaccacg aaaggcaaca tatgagagac accgttcatt aaatttttat agatgctacg
     7141 accaaaatta gcaccactca tcgcttctgg ttctaaagta tcagcagctt cattatctgc
     7201 taagacagta ccttttcctg ccaatgcttc gtcaatcagc cgttgtgcat ccttgattcc
     7261 tgtactgaca gaaacatcaa tgactcgttt tcccgcaaat ctttctgaat ggacatcttt
     7321 atctgcggca ataatgacag catctgcctg tttgatttct tcagccgtta attcattttc
     7381 gatcccaatt tgtccatggg tctccacttt gatcttgatg ccttttttcc tagctgcttg
     7441 ttctaatgcc tcttgcgcca tgtaagtatg cgcaattcct gtcggacaac cggttgctgc
     7501 aattagttga tattttccca tgtttcaaac ctctcttcct tgattttgat ttgtttactt
     7561 aattcctcca catccaaaaa atcagtcagt cctttacgaa aagcggttga gctgcctgct
     7621 gctatgcttt tacgtaacgt ttcatcaagc ggtcgtcgat tcatatatcc tgctaaaaaa
     7681 gcgcctaaca tggtatcacc tgcacatgct gtattgacaa cttttccttt tggcgagttt
     7741 cctcgaaaca ccctgtcttt cgtaaaaaga atcgctcctt tctcaccgag ggataacaaa
     7801 acattttctg cacctaactc tactagtcgt tgtccataaa caaagtaatc ttcatctgta
     7861 accatttttc gtccgaacca agaagaaagt tcttcctcgt tcggtttcag caaaaacggt
     7921 cgatagggta aacaatccat ggcttcttga tcactactat caataatcaa atgaatcccc
     7981 ttttcctgac aaatccgact gatttctatt aaaacctttg gagacagccc tcttggtaaa
     8041 ctcccagaaa cacaaagata atcttctgct tgtaatgctc ttatttgatt taaaaaatta
     8101 tggacagctg tctgcggtat tttaggtcct tgattcacta atttgtattc ttctcccgtt
     8161 tgattgactt gtgtaaatac attgatacgc gtcataccag gcacttcaat aaactctgtt
     8221 tggatttgtt tctgctgtaa atagtcttct atatactttc ctgtaaaccc agcagaaaaa
     8281 cctaatgccg tacttgggaa atctagcatt tttaatacta gtgacacatt cacccctttt
     8341 ccgtttgcct gaatgtcatc ctcttttgtg cggtttacca taaaaggatg catctcctct
     8401 gtttcaataa atagatcaat tgccaaattc atcgtgcatg tgtagataga cataaccaac
     8461 gacctccttg actctattat gaaatacgcg aaagagaaaa tgttttctta atcgtcccaa
     8521 cacaaagaaa acctttacat ttataaactc gtcgtgctat tttttaacta acttttggtg
     8581 aaagaaggaa agaatatgga tcacaaatta agtgaaacag aacagtacct ctggaacttt
     8641 atcgaacacc acatcctaga gatccctaac tactccatcg tgaaactaag tgaacaagca
     8701 aatgtctcaa cagccaccat tgtgcggaca atgaaaaaga aaggctatga aggatttact
     8761 tcgtttaagc accatctaaa agaaggagaa aacaagaaca tcaatttttc tttcttagat
     8821 aaagtagaca aaggtatccg tcgagccatt ctaaaaaatg aacaagaagt ggtacgtacg
     8881 atcaatatgt tggaaatcgg aaatattgag gatgcaatac aaagaatcaa atttgctgac
     8941 cgggtttttg tctttgcacg aggattttca gaaatgattg gtcaagagat gctcgtaaaa
     9001 cttcaattaa cagggaaaaa ttgtcaaatg catactgatc cagaaatcat caaaagcatc
     9061 agtcggaaac taactaagaa agacagcgtt atttttgttt ctttgaacgg cgagacaaaa
     9121 gaactcgtca ccgccgcaaa gaattgctat gatgcagaga ttggttcgat tctagttaca
     9181 gccaatcatt cctctacact gaaagactat tgcgagatca atctcgtagg tttcaaatca
     9241 gaaggttctt atttccctga ttatgaagta cggtcacgtt tgcctctcca gattatagcg
     9301 agaatcctgc ttgacgccta tgtattgcgt atgggggaga attgaaaagc agtttattat
     9361 ggttggttac agtttaaaac atcacatttt ttattcttta tattgtatgg actcacggaa
     9421 actttttatg tataaagtta ttcacaatct ataaagttac tttaaataac aaaaaaataa
     9481 ttgaaaatac ttaaaatcaa aaaatatctt tttaatcaat aaaaaaattg acagttttat
     9541 taataataag ctattctgtt atagaagaaa aaattgtttg ttattattag caacaaaaaa
     9601 aggagtgcat catgaaaaag ttatctcaaa aacgtttagc tcaaatcatt attgattcta
     9661 gaaaatctct gaaaatgaca caacaacaac ttgcagtagc tactggtatc aaccgtgcct
     9721 taattagtcg attagaatct ctcgatttta tcccgtcaat acaacaatta gaatcattag
     9781 cagaagttct aaattttgaa ccaacagatc tatttataaa tgaatcaaat aaatcaaaca
     9841 gaacaaaaca tcagtcgaag aatattgctg tagccggtac tggttacgta ggtctttcca
     9901 ttgctactct tcttgcccag cacaatcagg taacagcagt agacattctt cctgaaaaag
     9961 taaaacaaat taacaataag aaatctccaa tacaagacga ttacattgaa aaatatctag
    10021 ctgaaaaaaa tcttaattta attgcaacga ctgatggtgc agccgcctat agagaagccg
    10081 attttgttgt cattgctgct ccaacaaatt atgatagtaa acaaaattat tttgatactt
    10141 ctgctgtaga gtcagtaatc aaattggtgt tagaagtcaa tccaaaggca ataatggtca
    10201 tcaagtcgac ggtacccgta ggctataccg aaagtattcg taaaaaatac aatactaaaa
    10261 atattctatt cagcccagaa tttctcagag aatctaaggc attatatgac aatctatatc
    10321 cttcgcgaat tattgtcggc acggaccaaa ctgacaaaac tttacgagaa gcctctcaca
    10381 cttttgcaga tttactccaa gaaggagcaa tcaaaaaaga tatcgaaact cttttcatgg
    10441 gattcacaga agctgaagca gttaaattat tcgctaatac ttaccttgca cttcgagtat
    10501 cttacttcaa tgagctggat acttatgcag aaatgaaagg actaaataca caagaaatca
    10561 ttcacggggt ttgcttagat ccaagaattg gcacacatta taataatcca tcttttggat
    10621 atggaggcta ttgtttaccg aaagatacaa aacaacttct cactaactat aacgatgttc
    10681 ctcagaatat gataagtgca attgtcgata gtaatcgtac aagaaaagac tttatagcag
    10741 atcgagtgtt agaacttgct ggcacgtatg aggctaacag ttcgtggaat gcagaaaaag
    10801 aaaaagaggt agtcataggt gtataccgtc ttacaatgaa gagtaattca gacaacttcc
    10861 gtcagtcatc tattcaagga gttatgaagc gaattaaagc aaagggggca actattgtaa
    10921 tttatgaacc aacacttgaa aataacacta cattttttgg ttcaaaagta ataaataatt
    10981 tagatgattt taaaaatatc agtcacagta ttattgctaa tcgttacgat agtaatcttg
    11041 atgatgtaaa agaaaaagta tataccagag atttatttca acgagattaa aaaataacac
    11101 ctcagatttg tagtgtctga ggtgtttcta taaactttta taagtaaaaa aatacaatta
    11161 tacttcataa aaagacttat accactgcgc aaatttacga agcccgtcac gcaaacttgt
    11221 acttggttta aattcaaaat ctcgttctaa cgcactagta tctgcataag taactggcac
    11281 atctcctggt tgcattggaa ctagttcggt atgagattca aagtcgtaat cttctggtag
    11341 cacccctgct gcaattagct cttgttgtag aatatctaca aaatctagta ggttttccgg
    11401 cgtattgtta ccaatattat aaatatgata tggtgggatt ggtagcccat cttccccatc
    11461 aattttctct ggagcgcact gcataaccct ctttactcct tcaacaatat catctatata
    11521 ggtaaagtca cgcttgcaat tcccataatt gaatatttgg atattatcac cagcacgaag
    11581 tttatcagta aaaccaaaat aagccatatc tggacgccca gcaggaccat atactgtaaa
    11641 gaaacgtaac cctgtagacg gaatattgta aagtttagaa tatgcatgtg ccattgattc
    11701 attacttttc ttagttgctg catacaacga tacttgattg tctactttat cctctgtaga
    11761 ataaggaatt ttcttattag taccataaac ggaagacgat gaggcataca ctaaatgttc
    11821 cacaccagat tctccattat catatgaatg acgacaagct tcaagaatat tatagaatcc
    11881 tattatgtta gattcgatat acatatctgg attagtaatt gaataacgga ctcctgcctg
    11941 agctgctaaa ttcaccacga tacttggttt ataattatca aagatgaaat caattgttgc
    12001 tttatcagca atagaacctt tgataaaatt ccaagtagat cctggatggt tctttgcctc
    12061 cgtttctatc tctgataatc tatagttctt aatagagaca tcatagtaat cattcatatt
    12121 gtcaatgcca atgattttta ttgatgactg agtacgtaat aactcaagaa ccaaatttga
    12181 tccaataaaa ccggctgcgc cagttattaa tattgttcta tttgataagg acgtgtttaa
    12241 ttccagcatt ttttagcact cactttcttt ttttcttatg aatacatatt tgttatatat
    12301 taaaaaatct tatttagact tatctattgt cacttttatc attctaatct ttgcacgtag
    12361 tagaataatt atacagatag gaaattgcta agcaacccac ttctttctat tatctattaa
    12421 cttattctaa aacgaataga aa
//
LOCUS       DADGHT010000089        12144 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.090, whole genome shotgun sequence.
ACCESSION   DADGHT010000089 DADGHT010000000
VERSION     DADGHT010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12144
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.090"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..566
                     /locus_tag="JX887_002242"
     CDS             <1..566
                     /locus_tag="JX887_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAX1258185.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPASEAAKKDLIDILR"
     gene            967..1572
                     /locus_tag="JX887_002243"
     CDS             967..1572
                     /locus_tag="JX887_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HAX1258186.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1588..2160
                     /locus_tag="JX887_002244"
     CDS             1588..2160
                     /locus_tag="JX887_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1258187.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2412..2669)
                     /locus_tag="JX887_002245"
     CDS             complement(2412..2669)
                     /locus_tag="JX887_002245"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258188.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2795..3610)
                     /locus_tag="JX887_002246"
     CDS             complement(2795..3610)
                     /locus_tag="JX887_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258189.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            4127..5452
                     /locus_tag="JX887_002247"
     CDS             4127..5452
                     /locus_tag="JX887_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAX1258190.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5445..5795
                     /locus_tag="JX887_002248"
     CDS             5445..5795
                     /locus_tag="JX887_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258191.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            5777..5962
                     /locus_tag="JX887_002249"
     CDS             5777..5962
                     /locus_tag="JX887_002249"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258192.1"
                     /translation="MGSIRMNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSF
                     YVEAAAGYHKYEYYIGY"
     gene            complement(6866..7141)
                     /locus_tag="JX887_002250"
     CDS             complement(6866..7141)
                     /locus_tag="JX887_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HAX1258193.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(7113..8066)
                     /locus_tag="JX887_002251"
     CDS             complement(7113..8066)
                     /locus_tag="JX887_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAX1258194.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8678..10171
                     /locus_tag="JX887_002252"
     CDS             8678..10171
                     /locus_tag="JX887_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAX1258195.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            10306..10602
                     /locus_tag="JX887_002253"
     CDS             10306..10602
                     /locus_tag="JX887_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAX1258196.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10703..11554
                     /locus_tag="JX887_002254"
     CDS             10703..11554
                     /locus_tag="JX887_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258197.1"
                     /translation="MKSDDWIEHNWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11575..11787
                     /locus_tag="JX887_002255"
     CDS             11575..11787
                     /locus_tag="JX887_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258198.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         4172 a         1863 c         2268 g         3841 t
ORIGIN      
        1 attattttaa gtctgaaaag gatacatcgt ctctaacgtt aactttagag gaaggagttg
       61 aacctgacaa ggtgacctct aaagtgataa accaattgaa agaaaaaggt agtttgaaac
      121 atttggggga atatgaagtg ttagatacgg ctatgttaac gaaaggaatt ggtcaaatcc
      181 tcagtacgat cacttatttt ataacagctg tagcaggtat atctttattt atcgcagggg
      241 taggtgtaat gaacatgatg tatatatctg tatctgaacg aacaaaagag atcggtataa
      301 gaagagccct aggagctact cgaaaatcga ttatgctgca gttcctttta gaaggtttga
      361 ttttaactct ttcaggaggg ttaattggct atttattagg aatggctctt gcttatagtg
      421 ttggttcttt gataaaggta aacgtgtcac ttgatctatt tactatttta ctagcggttg
      481 gggtatcttc ggttattgga ctggtctttt ctgtaatgcc cgcttcagag gctgcaaaaa
      541 aagatttaat tgatattctt agataaaatc agaatgacaa gaatatttac gttctagatt
      601 ctaaaataaa acacaaagag accaaccagg caccctattg tttctttgta gtatagagat
      661 attctttggc ttgtaagaga tcaatagagt taggtgaccg gagttcgaaa taaaggaaat
      721 ttttgattgt ataggagaat tctttatccc taatatttag aattttgagt atgccatgtt
      781 gatgttttag attctctata aatatagagg tgtatcaaag gtcaactaga ctgtgcaaaa
      841 tagagacact tgaaaaatct atcgggggtc agaaacttaa tagtttttga cacataaaca
      901 aaatcgcgat ataatggggt tgagagtgtt tcataaactt atgtcataaa gttaaggaga
      961 tttcgcatga ttttagagaa taaattggga ttaaccaatc aagttgagtt ggctaaggtt
     1021 gaagaaaaac tcagtaaaca aaaagcgaaa gaattgtacg attgtggaaa aataaatgaa
     1081 atcgaagttg gtacatttaa aggtttatct gaaattcatg aatttctatt ttcggatatt
     1141 tacgattttg ccggaaaaat ccgatcggtc aatattgcaa aaggaaattt tcgatttgca
     1201 ccagttatgt atttagaaca ttcgttacag catattgatc agatgccaca aacttctttt
     1261 gaagagatta tcaagaaata tgtggagatg aatatcgctc acccatttcg agaaggaaat
     1321 ggccgaagta ctagaatttg gctggatctc attttaaagg aagaattgca aaaagttgta
     1381 gattggaact taatcgataa agcagactat ctttctgcaa tggagcgaag tcccataaac
     1441 gatttggaaa tacgctatct aatttccaat gctctgactg ataaaattga cgatcgcgag
     1501 ttatatatga aaggaatcga tgtcagctat ttctatgaag ggtattctga gtatacgata
     1561 gatgatttgt aaaagtaggt ggaccaaatg acgaaatatg gatatgcacg tgtctcaacc
     1621 gcttctcaaa gtacaaaaga acaaattcaa cagttgcttg agaacggcgt agagaagaag
     1681 aatatttttt cagaaaaatt tacgggtaca aaacgggatc ggccaaaatt caatcagctg
     1741 ttggctggtc tgaagcctgg agatgaaata gttgttacga agcttgatcg atttgctcgt
     1801 aacacgagag aagcattaga gatcattgaa cctttactcg atgataacgt aacgatcaag
     1861 gttttgaatc taggaacgat tgaaaatacg tccatggggc gaatggtgac acggacgttg
     1921 ttgagtgtag cagaaatgga acgtgatatg attgtggaac gtacccaaga aggaaaaatg
     1981 tttgcaagaa agaataatcc taatttcaga gaaggacgtc cgaaagcaac aatcacaccg
     2041 aagaagaggc acgcatatga actgcttact tcaggtaaat cgtataagga agttgaagct
     2101 ataaccggtt tcagtcgcag tacgcttttt agaataaaga agaaaattga agaaagttaa
     2161 aaaagaagtc tcagcgaacc agacaggtaa atacttaatg cgttctagat atgagtctat
     2221 tagcatgttg tgaaatataa tattttttta tttacttgat ttctgctcaa aaaatgtgta
     2281 tggtaactgt aaaaggtaaa gtaattaaag gtatgctagc cacgcttact atattaggat
     2341 accatcatat atttataatg aacgatttgt tcgtctacca aacaacacat atcgttcagc
     2401 gtaagtcacg tttaggaacg tggctttttt agtgttatta tcgataaata atctattgac
     2461 tctattgatt ttatctccat atccctacgg tgttgattgt ctttagatct ttcatttaag
     2521 aaccaaataa ctatcataaa aatcagcact gctgctaata taataaacag cattcctatt
     2581 gtgatattac ctattgattt taccataact acgattaaag taataatggc attcaagtct
     2641 cctttgttct ctatatataa attagccata aatcatcttc ctttcaaatt aagatacttg
     2701 tttgatacca ataaatagta agcgtggcta gcataccttt ttctgtaata gcaagtgttc
     2761 taatagtcca aacttaatga tggaccgatg ctagttatag tacagtaatg ttttctttct
     2821 tatctagatt tttagtaagc tctatcagca aatctaacaa atctgagtcc ttttcagaaa
     2881 ctaaattaaa tctagtgttt acaacaaagt tttcatgttc tatattgttt agattatttg
     2941 cggaaaggag ggcttctaga tcttgacatt caaatctata tgcatcgtca taaatcttac
     3001 tagaaggagt gcttaattcg aaattactta ttttctcatc ttggaccaag ataaatttat
     3061 agatagtatc tttttgtgtt tttcttttaa aaacacaaca gagtgtgtta taaggaacgt
     3121 tataattttc atcagcctca ttttttctcc attcaaacaa atgataaact gcaaccaagt
     3181 tgccatcaat ttcatggaca gtgctctcgg taacatcctt taaagaacta tcaagggcta
     3241 atttatagta actagagaga ggaagtaaaa ttgtcgattt actgagatgg ttatcgtcta
     3301 tacgtgcaat catacctaaa tcaactaagg ttttattcca ggtgtttata gttttagttg
     3361 tcactcctag agactctgct atggtattga ccgaatgcca ggaatccccg ccttcattct
     3421 ttgccttaaa acagtaatac agatataaat taatagcttt gttattcggt aaatattttt
     3481 caagttctgt tggtagaata aagtaagaat ccttaatgtt ttttctgaac tgtctccagt
     3541 ctctgtagtt ttgtttataa agttgtgaaa cggtttttcc acctttagaa agtcctgcta
     3601 tcttaaccaa tcttattgct cctttcttga atctgtcatg atcatacagt attttttact
     3661 tgtagtccag caccttaata tattatccta tgtaattaat ttcgtactag atagtaatta
     3721 ttttttattt aattctctag tcacttacaa ataagttata taaactacga ttaataaatt
     3781 attacaaaaa ctattaagaa aacttctaca tacaactatt acaaaactat taagaaactg
     3841 aatactccta ttttttgttt ttaaggaaag ttttttcttt tttgaatttc ttattttttt
     3901 ctaatataac taagcaaaac tggataatac gacacttatt ttcaaatttt cacaagacta
     3961 atagtaaata tccatttaat aaagtgatac aatgtgttga ttttacaaat caacagaaga
     4021 agtagggaaa taacttacct atgcttcttt ttttgtacat ttaatcgatt cttctttaca
     4081 aaaacgaacg tatgtttgta taatgtggaa gaatggagtg ttatttatga tggattattc
     4141 aaaagagcca gtaaatgatt actttttgat cgatatgaaa agcttttacg caagtgtcga
     4201 atgtatagaa aggaatttag atccattaac gactgaatta gtcgtcatga gtcgagcgga
     4261 taatacagga tcagggttga ttttagcttc ttcaccagct gcaaagaaga agtacggtat
     4321 ttctaatgtc agtcgaccac gagatctacc gcaacctttt cctaaaacgt tacatgtcgt
     4381 tccaccacgc atgaatctct atattaagcg aaatatgcag gtaaacaata ttttcagaag
     4441 gtatgtagca gacgaagatt tattgattta ctcgatcgat gaatcgatct taaaagtgac
     4501 cagatcaatg aatcttttta cgactgaagg aacaagaagt caacggagaa agaagctggc
     4561 tcaaatgatc caggagaata ttaaagaaga gctaggattg cttgctacag taggtgtcgg
     4621 agataatccc ttattagcta aacttgcttt agacaatgaa gcaaaacata atgatggatt
     4681 ccttgctgaa tggacgtatc aaaatgttcc tgataaagta tggaatattc ctgaaatgac
     4741 agacctttgg ggtattggat ctcgaatgaa aaaaagactc aaccaaattg gtatcatgag
     4801 tattaaagac ttagctaatt ggaatccata cactattaag agccatttag gtgtgattgg
     4861 cttacagctg tattttcatg cgaacgggat cgatcgaaca gatatagcga tcccaccaga
     4921 accgacaaag gaaaaatcat atggtaattc acaagtgtta ccacgagatt ataccaggag
     4981 aaatgaaatc gaactggtgg taaaagaaat ggcggaacaa gtagctattc gtatcaggca
     5041 acataactgt aaaacaggtt gtgtccattt atacattggc acgtcgatct tagaaacgag
     5101 accaggtttt tcacaccaga tgaagatccc tataacagat aatacaaagg aattgcagaa
     5161 ttactgtctt ttcttgtttg ataagtatta tgaaggacaa gaagtaaggc acgttggaat
     5221 aacctatagc aagcttgtgt acactgattc gcttcagctg gatttattta gtgatccaca
     5281 aaagcaaatt gacgaagaaa atttagataa aattattgac aagattcggc aaaaatatgg
     5341 ttttacgtcg attgtacatg cttcttctat gttagaaggc gctcgtagta ttactagaag
     5401 tacattggtt ggtggccatg caggcggcgc aggagggctt aaaaatgatt gattataatg
     5461 atcgtggacg tttaaagtgg gcaggttttt atttatctga tcatactgaa aaaattgatg
     5521 ccgacaatga acaacgagcc aatcaaaatt tggcaaaaga acaaatgacg actgaagagg
     5581 ttgcggaagt attgaacgct gcagtcataa aaaatagatc agtatgtatt caaaaagaag
     5641 aacgaaacgc tgaaggatac tatccagaag atattgttag caagatctta ggtagtgatg
     5701 agctggggat ctacgttgga aaaaacaaag ttcactacga cgaaatacgt catatcgaat
     5761 tttaccagga taataaatgg ggtcgattag aatgaacatt atccagcaat atgagctaaa
     5821 gtatataacc tttgatcagc tatcagaaga gatttggggt tatggccagc gtttgataaa
     5881 tgaggttggt gttgaacgct tctctttcta tgtagaagct gcagcaggat accataaata
     5941 cgaatactat attggctatt aaagtgcaat aaaattatat ttcttttatg ttttacattt
     6001 tgtatcaatt ctgataaaat tacctatagg taattaaaaa atataaaaaa actagttaca
     6061 accttaggac gttgtaacta gcttgaagca tactagagct aactaaaata gcactagaaa
     6121 gcaatgttaa acccgtccaa caaacttgat ttaacattga gaccagctta ttcagctaaa
     6181 tatagttgaa taagcttctt ttgttttaaa aaaacaaaag gtgtactacg aataacgcaa
     6241 gtaaaagaaa tactattaca accagtaggc tacaagtaag tattactaaa cattgcgtag
     6301 ttagaacctt tgctctattg tctaaagcca caaaattaga gatcagcttt atgatgctaa
     6361 gagcgagctg catccatgcg gacataggtt cttttgacac tattaattct cctttttagg
     6421 ataagggaaa ttgctagtag ttttttcatt agcaccatcc cccttcattt gattgagtct
     6481 agtgctgctg tgatagtttg ctgtttaata tgcttacatt cttattataa cataaatgaa
     6541 acaaacacat ggttagaggt cgtatcaatc aaaatagtgt ctcacaaacg atttattact
     6601 tactcctgct gactaacgga ctgttcttca gtaactgtaa ctatatgttt gttaaaacca
     6661 ccattacctg tagataaaaa ccaatatatt tactatactc actatattaa atatatttag
     6721 tatagtaaaa actagaaaca ataaaatttg tgaatgttgt atacccccaa acaatacaca
     6781 tattttgaag gattaggatt aataaagcta aaaatatagt aagtatacta aatatattta
     6841 ctatatctag tatacttact atattttaat cttttgatcg tctattatat ataatccgtt
     6901 cctcgtcgtt taaagtatca acataggcgt ccattgcaag tttgactatt tcatacatag
     6961 gaatatcttt tgcataacta agatcccgaa tggtttttag tacgggagga tctacttgaa
     7021 ctggttttct ttctttcgca gtgtactttc gttcccctaa ctcgacatta atatcatctt
     7081 taattgaaat atcttcagca ccaattttct tcttatcttt gttcgttggt aataatgcca
     7141 tttagtttaa tctcctttcc aagaggtagg atatgattgg ccattgagtc agcatattta
     7201 ggtgtataat caaatccttc aatatcacca tgttgttcat agtattcaat tctttcttct
     7261 aattctgtaa agatgtctgc aaaaatagcc caccatcttc gatctacata atcatttaat
     7321 tggataccat tctcaccata catttctaac cgatccgagc ctttaacaat gcttttaaaa
     7381 atgtttgatt caccatactt atcaattgtt ttttgatagt ttgcgtgttg agaggaacgt
     7441 cgcactgaga aaagaacagg caaaattcca atgatttgaa gatgagactc ttcaaaattc
     7501 gtgacaatcg gaactaaaac tttattaata aaatcttctg ttccttccat tgcgtaccgt
     7561 tttaattctt gcattgcaat aatataatct gcagcagtta agaatgcacg aaccacatta
     7621 tctgttgatg gtgggcagtc gataaagata taatcgaaat tttttctcaa ttcttctaaa
     7681 ggtttaatga aggccaatga tctcttacga cgatcaggat atttttcgga caagtattca
     7741 ttaagttctt cagatccagg agagccagcc ataatatata aatgtggact tacttgagta
     7801 atacctgaaa cccagtcccc ttttttgatt gctgcagaca tggatcgatc aaagctagta
     7861 atttgatacg ttgatccaat gttggaagta gtatttcttt gttggtcata atcaattagc
     7921 aacacgtctt tttcaaaaag ttgactagaa acaatcgcta ataaatcatt gtctgtagtc
     7981 ttaccaatgc cgccttttct acctgtaagc attacaactt ttcctagttt atctgatgtt
     8041 ttaaatgcag tccgtaagtt ttccatagtt ccctccaatt tcctatacta aatatattta
     8101 gtatacttca tatacttaat atattcgata tatctaatat actccaaatt gataagaatt
     8161 cagactttat aaggaatata gtggatatac taaatatatt tgctatattc agtatatcag
     8221 atatattcaa aatgtcaaaa tatatttgtg cgttttgcgt tgacaattta gagtgaaaag
     8281 aggtaaactt aattctatag aaaccacaga taattcacta tttacaaagt agcaaaagca
     8341 gtggtactct ttaaacagaa aaattacata aaaaaaagag acggaaataa ttgattttag
     8401 cagaatcaat tatttctgaa tcacatggtt aggacatgtg ttcacgctcg tctcaagaat
     8461 atgtaagtag ctaccaacta cttatattaa aagttgatcg gatacctttt ccgattgcct
     8521 ttattctacc aaaaaaaggc gagcaactca acagaagaac gtttatttag tgtacttaaa
     8581 ttaaatattc ttaaacactg aagagagaac acatactatg gctgagatta aagctaaact
     8641 gtgttctctt tttgtttgag aaaggacgtt acaatcgatg ttgagcgaaa tttattcagc
     8701 tattcttaaa aacggcttac gtacatacaa atatcgaaac agcaccatga aacctgcagg
     8761 tcatattgat tccagtagga gtggtgctat ctttgcgtac cgtagcaagc aattaatgaa
     8821 tgttgggcgt ggtatggtca ttacttcgga agaagctatt ttagagaacg aaaagaaact
     8881 aacgcattgg acacctaata cctatcgctt tggtacttat gcggatgatt atcgaacagt
     8941 ggttaaaggt cattctgaga aaaacttaag tcaaatcaac acatttgtag ttgatatcga
     9001 ttcaaaagag aaccatcaag gcgaaattat tttagcctgt ttagatcaag tgggctacat
     9061 gccaacgcta attttagaat cagatcatgg ttatcaagtt tattttgtac taaagacacc
     9121 aggctatgtc acaaagaaaa gcaatttcaa ggtgatcgat gtagcaaaaa aaatttcaaa
     9181 aacaattcgt ctacagttgg ctgaaaaatt gtccggagtg gatctaggat gtaaccactt
     9241 cggaattgct cgattcccac aagaaaataa tattgttttt aaagaaatga actatcagta
     9301 ttcttttgct gactggattc aatggtcgat gaagcttgaa tcagatcaaa aaacaaaaga
     9361 agatcgagaa cgaaaactaa ttgtctttcc tgagaaaaaa gaaattcgtc aagtagatga
     9421 accgtggttc gatatgttac ttcataaagc aaacatcgtc ggcggagaag gacgtcttgg
     9481 tcgaaataat gtgattttca cgctttcttt agcttattac tcttcaggtt atgcattgga
     9541 tacttgcgaa tacaatatgt tcacattcaa cgaacggtta caggaaccgc tatctgaagc
     9601 agaattagta aagattgtac gtagtgctta ttctggtaat tatcaagcag caagcagaga
     9661 attcattatt gaattgtgcc agcaatgggt ttcaccaacc ttaaaaaata atgatctgtt
     9721 cattcaacga cgtggctggt ggaaatttaa aaagccacga gatcaaagaa aatatagtca
     9781 taaaaatgaa tggaaagaag atctattggc ttatctaagc gaaaaaagtc ttgctagtga
     9841 gccttatttg aacctgtcaa aaaaagaatt ggcttcacaa ctaacgatgc ccaagcgaac
     9901 acttgataag atcttaaatg agttacgaga ggagaataaa gtcttctaca aggtaacacg
     9961 aggaagaaat ggcggaatga tcattgcttc agtcaaaacg ttgttcgcga gggttattca
    10021 actaagtaaa gaaaagagac tagattattc aacaaggatc acagaggtat ttggactcaa
    10081 cgagagctta gtagaagaga catttagaca attatcaacc cccttgaacc ctcttaaaga
    10141 agtgaatctt tttgaagtag atacaggttg aaaaataaaa ggtgcaaatt gccttataca
    10201 atatatctat gatacttctg taggtgttgc tccctttgcc tagctacgtg taggtggtat
    10261 acttataact gcgtatgcag tcttatgtat catggaggaa gttgtatgtc gttaaaaaat
    10321 tatgtctatt cacatcctgt taatgtgttt atcattggtc gtttgggatt atctgtggaa
    10381 gtgttctgtg agctttatgg ttttaagcag gggactttgt cttcttgggt taccagggaa
    10441 aaaacagttg cttctttgcc gattgagttt cttcatgggt tgtccttagc ttctggggag
    10501 actatggatc aggtatatga ttgtttgtgt gtgttagagc aggagtatat tgagtataaa
    10561 atagctaacg agttaagaaa aaggaagaag tatatccagt agtagttttt atttacttaa
    10621 aaaattggtt cattgagcaa cctatcgctg ctaaagtagc aaaggaaaac gttaaaggaa
    10681 agaatttagg gaagaaatcg aaatgaaatc ggacgactgg attgaacaca actggcttcc
    10741 tctgaaaaga aatagcaaac gaaagaaatt ttgggtattg caattatggc cattaggaaa
    10801 actttgtagt tacggggcac gacttattct tgatttaacc gtttactcga ttggagtatt
    10861 tggaacggct tattacttga taaatgatcc caataggatt gcagcatcag acatttttac
    10921 agtgctaatg acgttgattt ttgtcatgct attgtctatt tttactcaat tagtcatgca
    10981 atttaccagg caaaaattaa cagcaggaaa acttttcaaa agcctattcg atttaattgt
    11041 tgtaaatgca attctagcga ctttaataaa acaaattgaa caatctggaa gaacaacaaa
    11101 aggagtgaag gattttttat tgacgtttat tcactttgta aatggacaca tgtatttgtt
    11161 tgaagtgggt attattctct tttttgtcgg gtatgtatcc acgaaactta ttaaacgttc
    11221 aattgaaaaa gaaattgaaa ttgacctgat tccgacactt cttggttatg agtacaatgt
    11281 tgattttgga agatatgacg aattgatcaa tacggatatc gttcacacga gtatccatga
    11341 atctactgtt aagggcatca gatctatttt aaaaaatggc caggaaatga aagcaataga
    11401 tcgaagaaaa gagatctaca atttttatga agtcgaagca agcctacgat atggcatcgg
    11461 aaaattgtgg ttagatggaa gtaatattcg tcaaaacaaa ccatacattt tttggaacag
    11521 tagtgattta gaacttccaa tgaaagataa ataattatgg agaatcgttt gaaaatgatt
    11581 cctctataca ggattgtgct tatagttggc atggagttaa aaaccttaaa gaaggagcag
    11641 ttattcaaag tgaaagaacg tcataatcag ttactatgta gtaaaacggg tacgatgaac
    11701 attgaatacc gaacagaata tttagaatta acgaatcaaa ctgatttttt gttgattcga
    11761 aagcaacaag agcaagaaaa aaattaatgg ctacttatag ccaattgatt gatgaatggg
    11821 aacaattcaa ggaatctaaa attccagaac gtctctaaaa gcctttattt gtaaagagca
    11881 taaggaaacg tgggaacact ttttaaaaaa agtgttccaa taggctgtgc ctattacgtt
    11941 tctcaaaaat aaatgtggga acaaaatatt taaaaatagg atagtgaaag gatagtgaag
    12001 gatagtaaaa ggagggtagt aggatagcaa aaaggatagg ctccttttcg ctatcctttt
    12061 taaattggag gaattaatat ggaagtaaga ataagaaatg tggatgagaa aatcgtaaga
    12121 gaaattgatc gaagatgtga cgaa
//
LOCUS       DADGHT010000090        12123 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.091, whole genome shotgun sequence.
ACCESSION   DADGHT010000090 DADGHT010000000
VERSION     DADGHT010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12123
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.091"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            544..1872
                     /locus_tag="JX887_002256"
     CDS             544..1872
                     /locus_tag="JX887_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAX1258199.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2074..2907
                     /locus_tag="JX887_002257"
     CDS             2074..2907
                     /locus_tag="JX887_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAX1258200.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2923..3660
                     /locus_tag="JX887_002258"
     CDS             2923..3660
                     /locus_tag="JX887_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAX1258201.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3815..4783)
                     /locus_tag="JX887_002259"
     CDS             complement(3815..4783)
                     /locus_tag="JX887_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAX1258202.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5015..5848
                     /locus_tag="JX887_002260"
     CDS             5015..5848
                     /locus_tag="JX887_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAX1258203.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5882..6721
                     /locus_tag="JX887_002261"
     CDS             5882..6721
                     /locus_tag="JX887_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1258204.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6747..7307
                     /locus_tag="JX887_002262"
     CDS             6747..7307
                     /locus_tag="JX887_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAX1258205.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7506..9227
                     /locus_tag="JX887_002263"
     CDS             7506..9227
                     /locus_tag="JX887_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAX1258206.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9392..10534
                     /locus_tag="JX887_002264"
     CDS             9392..10534
                     /locus_tag="JX887_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAX1258207.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10550..11761
                     /gene="thiI"
                     /locus_tag="JX887_002265"
     CDS             10550..11761
                     /gene="thiI"
                     /locus_tag="JX887_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAX1258208.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4130 a         2034 c         2520 g         3439 t
ORIGIN      
        1 ttttattatt atgatgaatc aagctttctg tttttgtcac gtatgttgta atctttacga
       61 aagagtagag ttggctactc ataatcaacc atacttccca tcatcgctaa atacgaaata
      121 aatcagcatt cctacaccaa tcaaagcaca agctgcacca agaaaaggga tgacattccc
      181 aaagttatct gtattcataa gtatgccacc acccacaaac aaaaagccgc cagcaatcag
      241 gtttttcatt ttattcatct cctttcttac gttatagtat ttccttcttt caatgagtat
      301 tttgaaagct atcttattgt atgatgttct tctaggcctc ttctttatta tacaggccat
      361 tttcgttatc tcatagaaat attccttttt atctgaaaac tattgtatac cgtatgacat
      421 ttttcttcat gaagttgtaa gtatattctc attcaaatga aaatttcatc atagaagaga
      481 ttgtatttct aaattcttaa gagtaaaata cgaagtataa cttggatttg gaaggatgat
      541 tggatgaaag ctattacgcc tgatatgaca acaaaattta acaaacagtt tcaagcaaat
      601 atcaaacagc aggcattgca gcgggcagtt gtgaagaacg gaattactgc ttctgctgaa
      661 aatgtttcag cacatgtgga gaatacaccg gtattttcta tagatttggc tacggggaaa
      721 gtggctaatc aaatgcaatc ggggcgttgc tggatgtttg ctgcactgaa cacattccgt
      781 cataagatgc tgaatcaatt ccatttaaaa gagtttgaat tatcacaaaa ttacactttt
      841 ttctgggata aatatgaaaa ggcaaattat ttctatgaaa acatcattgc aacaggaaaa
      901 gaggcaatcg atagccggaa agtagctttc ttactcgcta ctcctcaaca agatggcggc
      961 caatgggata tgatcgtttc attattccaa aaatatggcg ttgtgcctaa atcggtgatg
     1021 ccggaaagtg cgaatagttc aaattctcga gatttgaata actacttgaa caaattactg
     1081 cgtaaagatg cagtagtgtt acggaaaatg gttgctcaag gagaaacatt agacgctatt
     1141 gaagaaaaga aagaagaaat gctagaaagc atttataact tcttagctat ctcattagga
     1201 acacctccaa aagaattcga ttttgagtac cgcgatgaag aaaagaacta tcatcttgac
     1261 cgaggactga caccacaaat tttttatgat aaatacatcg gtgtaaaatt agatgattat
     1321 gttagcgtga tcaatgcacc aacaaaagac aaaccattca atcgttctta tacagtagag
     1381 atgctaggaa atgtcgttgg cgggaaagaa gtcaaatatc tgaatgttga tatggaaact
     1441 ttcaaaaaat tagcgattgc tcagcttgaa gaaggagaat ctgtttggtt tggttgtgat
     1501 gtaggtcaat cttctactag aactagtggc atcatggcct tagatgctta ttcaatggat
     1561 gatctatttg atacggattt tacaatgact aaagctgaac gtttagattt tggagaaagt
     1621 ctgatgaccc atgcgatggt attgaccggt gttgacttag tagacgggca atcaacaaaa
     1681 tggaaagtcg aaaatagctg gggcgaaaaa gttggaaaga atggcttctt tgttatgagt
     1741 gatgcctgga tggacgaata tacgtaccaa atcgttgtaa gaaaagattt attgacgaaa
     1801 gagcaattaa atgcgttcaa tgaagaacca attgttctat ctccgtggga tccaatgggt
     1861 gctttagcat agacgagtat ttcaatgaag agtatgtagt aaagataaaa agagctggct
     1921 taagccagct ctttttatct ttaaagtcca ttccctgttt tttatggtcc ctgtgctata
     1981 attctaaata aaggataagg attggaaata atccttttat cattaaaaat atgatgacga
     2041 agtagaataa aattgggagt aggggggaaa gtcatggata tccaaactgt tttatctgat
     2101 ctgaaattaa atggtaaagt gattccagtt gttggtggcg atgttaatca gacctatcgt
     2161 ataaaaaccg aacatcgtgc ttatttttta aaaatccatc cgaatgtaaa aaaaggattt
     2221 tttgaagcag aagtagacgg attaaaagaa ctgtcagcat tcgtacgtgt accggatacg
     2281 tatatgctag gtgaaacaag tgaaggcgct tatttgttaa tggaatggat cgagccggga
     2341 aaaggggatc aacgagatct tgctgcagct ttagctaatc tccatcagca aacagcgcca
     2401 caatttggtt ttcgtaaaga taactatttg ggtacacttg ttcagaaaaa ttcttttgaa
     2461 gaagattggt ggactttttt ctttaaagat cggcttgaat cccagatttc tttggcagaa
     2521 gaaacgaatc gatggaatgt acagcgtcaa gaaaagtatc tgcgatttaa agaacgtgta
     2581 ttgaaatcgg ttgaaccaaa aaagatcact ccacgcctct tgcacggaga cctgtggagt
     2641 ggtaatgtgt tctttgacca gcaagggcat ccagtttttg tcgacccagc tgtttcttat
     2701 gggaatcggg aacaagatat tgcaatgagc cagttattcg gtggtttccg accggaattt
     2761 ttagatgctt atcaaactat atttccatta gaaaagggat ggaaagaccg actgccgatt
     2821 taccagttat attatctttt ggcacatttg aatatgtttg gagaaagtta cggttcccaa
     2881 gtagatcaat tactagaaaa tttttaagag gagggcgtgt ttttggcaaa aaaatatacc
     2941 aaaaagcatg aagtttcata ttatgagtgt gacatcaacc aaacgatgac atttccttcg
     3001 atgttaggag tagttatcaa aacgtctgaa gatcaaagcg accagttggg aagaggcagt
     3061 gaattcgtca atagctttgg acttacttgg gtcatcacga attattccat ggagattaat
     3121 cgtctcccta gagtcggtga agtaatctca gtaacgactc aagccatgga gtacaataag
     3181 tttttctgtt atcggaactt ctggatccat gatgaagatg ggaaagaatt agtcaaaata
     3241 gaatctgttt tcgtattgat ggattttgtg aatcgaaaaa tgagcagtgt taatgaagag
     3301 atcattgctc cttttgagag tgagaagatc aagaaaatca agcgtcagga aaaaattgaa
     3361 aagattgatt cgggcttcat gttgccatat cgtgttcgtt tttatgatat cgatagtaat
     3421 cagcatgtta ataatgcgat gtattttaat tggatcattg acgtattagg atatgacttt
     3481 ttgactacgc atgttccaga aaaagtaatt attcgatttg ataaagaagt agagtacggg
     3541 aatgagatcg aaagccattt tgaacaaatc cctatcgaaa atggtgtcaa aacaaaacat
     3601 gaaatccgaa tgcaagaaca gctgtattgt gaagcaaata ttatatggaa aaataaataa
     3661 aaaagaggtt gtgacagaag ggggcaactt caagaaataa gaagaaattt acgaaaattg
     3721 tttctcaaat ttttgtaaat tttcgactta gttttcgaag aagctatttt tgtcacagcc
     3781 tctcttttta agtttagcta ttagataatg atgtttagtt ttggataaac gaaatcaatt
     3841 cttcacccga caaaccatag tttacagcaa tcaatagttt taaacgtgct ttttgactat
     3901 taatactgtt acagaaaata atccccattt tttctagttc ttttcccccg ccttcataat
     3961 cataaacagg ctctgcgatt ccattgaaac aacgagaaac aagtactaca gggatttttt
     4021 ggacaagaag cttttccaaa gcagctaagg cttgtggagg gagattcccc gcacctaaag
     4081 cttcgattac caaaccgtct actttcgtat gggcgatggc ttccaataag tccccttgca
     4141 tcccagcata tgctttaacg atcgggatag tcccatctac agcggaaatg tccagtcgct
     4201 ttgtttctaa aagttcctgc aagaataaaa ttcgattctt agttactaag ccgatgggac
     4261 ccaatgtagg tgttcggaaa gtagcaacat ttgtggtatg ggtctttgtc acgtagcgtg
     4321 cagaatggat ctcatcgttc atgaccacca aaaccccctt atctagcgct tcttcacaac
     4381 ttgcgacacg aatcgcactt tcaaaattat aaaggccgtc acttccaagt tcattacttg
     4441 aacgcattgc cccagtcaaa acaattggta atttgttgcc aatcgttgta tcaagaaaaa
     4501 aagcagtttc ttctaatgta tctgtaccgt gtgtgatcac cactccggat atacctgatg
     4561 cataagcgga caagatacgt tcttttaata ccaacatgtg agaaggcatg atgtgtggtg
     4621 agggaagatt gaagatatct tcaactaata attctacatg cttggggatt gtgatttctg
     4681 catctaataa tgggtttgcc acatcaggac taacaccgcc cgtgagcatg ttttctttca
     4741 tggcgatcgt tccgccggtg tgtagtacaa gtattttttt cattttacag acttccttac
     4801 gaataatttt gcatagccgt taaatcttat tgtatactat ataaaagagt tttgctatca
     4861 gtgaagaata acgaatagcc taacttatca taaaaaagct gaccttatta aaatggaaaa
     4921 gactcaacct tgacctccta atacaatgga gtatctggtt gagtttcttt tacaagaaag
     4981 cagccaagga aatcaatcac gaaggtggcc ggaaatgatc agaatcggat taacatcgtt
     5041 taaagaacat gacaaattaa ctggtaaaaa gaataacact ctttatgaat atgcagggtt
     5101 tctaccctta gtggaattag atactgccta ttatggaatt ccccgaaagt cctcagttga
     5161 gaattggata agtgaagtac ctgaatcatt tcgctttgta gtcaaagtct atcaaggaat
     5221 cagcggtcaa ggagactgga agccttatta tcagaccgaa gaagagatga ttgcgcattt
     5281 tttagatgtt atgtcgccaa tggtagatgc tggaaagatg ttttgctttt tagtccaatt
     5341 cccctcatca ttcaaatgta cgaaagaaaa tgtccagtac ttgcgcaaac ttagaaagtg
     5401 gtttgagggt tatcctgttt ctatagaatt gcgggattat tcttggtaca gcgatgaatt
     5461 tcttgaacgt acaagaaact ttatgtctag agccgctttt tctttagcca tcatcgatga
     5521 gccacagttg ctgaatacaa cgattccttt tgatccattt gtcaccaatc cgaactttgc
     5581 tctttttcga ttccatggta ggaatgcgca aggatggcaa gcaaatgata aagagtggcg
     5641 taaaaaaaga acgttatatc gttattcaga aaaagaactg caagaactag cacatgaagt
     5701 caaagtagtt gattctaaga caaaagaggt aggtgtgatt tttaataata attctggtgg
     5761 tgatgcggct gaaaatgcat tagcactgca aaaaatatta aatatcaagc cagatggact
     5821 caatccaacc caaatggatc tgttttaagg gcttatttta ttcaagaaag gggcgaagtc
     5881 tatgatcaaa gctatttttt ttgatattga cggaacattg gtcaccaatc gttcaaaagc
     5941 gttggaatca acaaaacaag caattgaata tgctcggaaa aacggcattt tatgcggtgt
     6001 agcaacgggg cgcagcccag taaagatcaa agaaatcatt gatgaattgg aattagatat
     6061 gtatgtcgtg tataatggtc aactggtttt tactgcagat cgcacgatta tcgaccaccc
     6121 ttttgaacaa aaagtattgg aacatattgt tgaatttgca gatgagaacc atcgacaaat
     6181 cgtttttggt gcgagaaatc ggttagatgg atcaacgacg atgctattag gacaatcgat
     6241 ttttatcaag cgactagtca gctttttacc gcgtaaattc ccggtacgtc tgatgaaaaa
     6301 aatcctccag gtttttagcc ctcaccgaca aaaggatcgt tatgaaacgt tagagatatt
     6361 aaaagaacca atttatcaat gtatattgct cagtccggag tcagaacaga aaaagttaga
     6421 acatcgcttt cccgagtgta cgtttcagcg ttcaaatacg tatactgtag atatcatccc
     6481 aaaaggtggt tcaaaattac taggcatcca agctttcgca aatgctgtcg aaattgaaat
     6541 ggaagaaatt atggcattcg gcgatcatta caatgatatc gagatgctga aaggtgtagg
     6601 aattggagtg gccatgggga atgctcagat cgaagtaaaa catgctgcag actttgtgac
     6661 tcaatcaaat gaagaagatg ggatatacga aggactgaaa cacttcggtc tgatttatta
     6721 gtcaatgaaa gaaggaaaaa atcagtatgg aagcagagac accttttcaa aaagtagaaa
     6781 cattccacaa aacttttgat ccaagaagac cagagatacc cacggctttt acagaaaatg
     6841 aagctcatac acgtgctgcg ttcaaaatag aagaacttgt tgaatttgtt gcagctactt
     6901 cacctaataa agaacaactg catgaagctg ttatgctgct gcacgaagca ttagataaag
     6961 cagaagaaaa aatacttggt aaaacacagt ggggaagtga tccgctggtt gaacaagtag
     7021 atgcactgac agatatcctt tactttactt atggttcttt ttcattacta ggaatagtgc
     7081 ctgatcgaat attcgaaatc gtccatcagg caaatatggg gaaattattt ccagatggaa
     7141 aacctcatta tgaccctgta acaaataaag tgttgaaacc tgaaaactgg cagatggaat
     7201 atgctccaga acctaaaatc gcggcagaaa tccaacgtca gattcaagaa gcgattgcta
     7261 agaagaaatc cgctgatata ggcatgtgca caaatgaaaa agagtgatca gagtttcact
     7321 atttttgtta tctttatacg atggaaaaac aaaagatttt cgtttaagtt agtgaatgca
     7381 tgaaaatagt atgctataat ctagaataga tgtcttttgc acgagagacg tattatttgg
     7441 atttatgcca agcagaacgc catctgttgc ataaaagatg catactgaaa acggaggaac
     7501 cataaatggg aaataatgtt atcatcggaa tcgtcattgc aatcattata gtcgccattg
     7561 tcgtcttttt ggttagttac ttgatgaaga aaaaaaacca agatcgattg gatgccttag
     7621 aaaaacgcaa ggaagaatta tttgacttgc cagtgattga agaagtcgat gatgttaaaa
     7681 aaatgcatct ggttgggcaa agccaaaata cctttcgtga atggagtcaa aaatggaatg
     7741 acatatctac ttcctcgttc gctgaactag aaagtcaaat tttcgaagtg gaaaacctca
     7801 atgaaagttt tcggttctta aaaggaaaaa aagcagttgt tgaagcagaa gctacaatgg
     7861 accaaatgga gaaacaagtg acggaaatcc gtgaaggtct aaaggaattg cgggaaacgg
     7921 aagaacgcaa ctcactagct gttcagcagg cacttgacgt ctatgaagaa ctgaaagaaa
     7981 aagtcagaga agacgagcat gaatacggac cagctctttt tgaattgcaa aaacagatca
     8041 aagtgatcga aaaagaattt acgcagtttg tgactttaaa cacttctgga gaccctgttg
     8101 aagcccgcga ggttttggat aaagcagaaa aacatacgta tgaagtggaa gctctgatga
     8161 aaaaaattcc accgctgtat gaggagctcc ataccacttt ccctgaacaa cttgaagaaa
     8221 tcagtgatac ttacgagaaa ttgatggaag aacaatatgt attcccagaa gaagatcttg
     8281 ctgaagatat cgcaaaagta agtcgaagaa ttgaaaattc attagccaat cttgaaaaaa
     8341 cagaagttga aacggtcgaa tttgaaaacc gtgaaacagc tgatttgatt gattcgttat
     8401 atgatatctt agaacgggaa atggaagctc agagatatgt aaaaactaac caatcaacga
     8461 ttgcagagta tatcaaacat acaacaaaga ataaccgtca attattgatt gagctggatc
     8521 acacatctca aagctataca ttgaaccaca atgaaattgg ccgtgtacga ggtttccaaa
     8581 ccgaagtgga agaaatggaa cgtcaaaatg aacagatgat tccacagatc cgtcaacacg
     8641 aaattcctta ttcagaagtg cgcacgttct ataaaacagt cttcaaagtc ttagaagata
     8701 tcgaaaagca acaagtagag atcgacgact cattacatga attgagaaaa ggcgaaaaag
     8761 aagcgcaaga aaagatcgat acattcgaat tcaaattgcg cagtttgaaa cgttttgtag
     8821 aaaaacaacg tttgcctggc ttgccgaatg attacctaga attctttttt gttgctactg
     8881 accgtattga agaactaagt gttgtcttga ataaaattcg agtaaacatg gaagaggtca
     8941 atcgtttagt tgctctatgt gaagaagatc tagaattatt agataagaag acacatgatt
     9001 tagtagatgc agcagcatta acggagcaaa tgctccaata tgcaaatcgt tatcgtcata
     9061 cacacgaaga agtgagagaa gcaattgata aaagctacta tttattcaat aaagaatatc
     9121 actatcaaga agcattagac gaaatcggta cagcattaga gcgagtagaa cctggtgctt
     9181 tcaaacgcat cgaagatttt tattttaatc atccagactt agtataaagc aaaaaagtta
     9241 gtaaaccagc aagagcaaga cggattattg tcttgttctt gtcttttttt gtatatttga
     9301 aaattgaaac aagtgaaaat ttcacctgct cttgaaagca ccttggacaa ccgttataat
     9361 agaaaagaat ttcaaaaaag aggggtttct tatgatatat tttgataaca gtgcaacaac
     9421 cccaatcttt ccgcaaagct tagatgcata tgtaaaaacc agtcagcgga ttattgggaa
     9481 tccatcaagc ttgcatgatt taggcaatca agctaaccgg ttgttgcagc aagcaagaaa
     9541 gcagatcgct gatttgatcc atgtagaacc agaagaaatc tattttactt caggcggaac
     9601 agaaggagat aactgggtat taaaaggaac gatgatcgaa aaaagagaat atgggaatca
     9661 tatgatcatt tcaggagtcg aacatccggc cgtcagcgag acagcagaac aattaaaaga
     9721 attaggaatc gaagtaagta tcgccccagt ggataaacgc ggatttgtac gtgtcgacga
     9781 attgaaagaa ttaataagaa aagagacagt attagtctct gttatggctg tgaataatga
     9841 agtaggatcg attcagccca tccaggaaat cagtgatctt ttggatgatt ttcctaaaat
     9901 tcatttccat gtagatgctg ttcaggcgat tggaaaagta ccattctcgc aatggttgac
     9961 agaaagagtt gattttgcaa cattttcagc tcataaattc catggcccac ggggaactgg
    10021 tttcatttat tggaaaaagg gtcgtcgttt agcaccatta ctgacaggtg gagggcaaga
    10081 aagaaatcag cgaagtggga cagaaaatgt tccaggtatt gtggctatgg ttaaagcttt
    10141 acgtttatca ttagagataa aggaacaaaa acctgagcag acacaacgct taaaagtagc
    10201 tctaatcaat gcgttgaaga cgtatgagaa agtgacgatt ttttcagaag gaactgacta
    10261 tgcaccgcat attttatgtt ttgctctaaa aggaattcgc ggcgaagttc tcgtccatgc
    10321 cttagaagaa aaacaaatat ttgtttctac tactagtgcc tgctcctcac gtaaacatat
    10381 ggcaagcagt acattgcacg caatgcatgt accaaatgat ctggctacat ctgctgttcg
    10441 aatcagctta gatgaaaaca attcgcttgc agaagtcgag caatttatga ttattttcaa
    10501 gcagctttat aagaaatttt ctgcaatcaa ttaaaagagg agtgttcttg tgaaatacag
    10561 tgaaattatg gtccgttatg gggaactttc gacaaaagga aagaatcgaa aaagctttat
    10621 catgcaacta gcacaaaatg tcagacaagc tttgaaagac tttccagaaa tcaaaatcca
    10681 tgctgatcgg gaccggatgc atcttttatt gaatggcgca gacgggcagc tagttattcc
    10741 aaaactagca aaaatatttg ggatccaaaa tttctctcca agtattcgtg tagaaaaaga
    10801 tgtcgaagtt ttgaaacaag ctgttcaaga catcatgaaa gaaatttata ctgggaaaga
    10861 aacatttaaa attatcgcta aaagaagcga tcaccaattt gaattgacaa gtaatgaatt
    10921 gaatcaaaca ttaggtaatg ctgtttttga tattttcccg catatccaag ttcaaatgcg
    10981 tcaaccagat attccattac gtgtagagat tcggcgtgat ggcgcttatc tatcgtatga
    11041 aacgatcaag ggagctggag gattgcccgt aggaacaagc ggaaaaggaa tgcttatgct
    11101 ttctgggggg attgattctc ctgtagcagg gtactttgcc atgaagcggg gagtggaaat
    11161 tgaagctgtt cattttgcta gtccgccgta tacaagtgaa caagcactgc aaaaagcaaa
    11221 agatctaaca gccaaactag caccttatgt gggaacgatc cattttatcg aagtgccatt
    11281 taccgagatt caagaagaaa tcaaaaagtc agtgccacaa ggatattgga tgacaattac
    11341 tcgtcgaatg atgttgcgtt tgaccgatga aattcgccgt attcgtcatg gtttagtcat
    11401 tttgaatggt gaatcattag gtcaagtggc ttcacaaact ttgcaaagta tggtggctat
    11461 caatgaagta acgaatacgc caatcattcg gcctgtagcg acaatggata aacttgaaat
    11521 cattgaagta gcagaacaga tcgatacatt taatctttct atccagcctt ttgaagattg
    11581 ctgtacgatt tttgctcctc cacagccaaa aacacgccct caactggaaa aggtccatca
    11641 atatgaagag cgtttagcaa tagatgaaat gatccaacga gcactagctg gcttgaagat
    11701 ggaagagata caagcagaat cgtctaatga aaaaactgaa gaattttcag aattgctata
    11761 agaggttatg aaaatagtgt tttgaccaga gtattagaga aacaaaacga aaaaatagct
    11821 ccatgtattt taccgttttt gaactaatgt cgaagattag ctgattgaat accatttatc
    11881 aagaagttat ggaaaagccg gttctttttt actaactgaa aaataaaatt ttatttagag
    11941 atcaagctac agttgataaa tgatataaaa aagagaattt cccatgaaat agcgaggttg
    12001 tgacagaagt gggcagcttc aagaaataag aaggaattta cgaaaattgc ttttcaaatt
    12061 tttgtgaaat ttcggcttat ttttcgaaga agttacttct ggaacaccgt gtatcagagg
    12121 ttg
//
LOCUS       DADGHT010000091        11590 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.092, whole genome shotgun sequence.
ACCESSION   DADGHT010000091 DADGHT010000000
VERSION     DADGHT010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.092"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            104..967
                     /locus_tag="JX887_002266"
     CDS             104..967
                     /locus_tag="JX887_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAX1258209.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1096..2718)
                     /locus_tag="JX887_002267"
     CDS             complement(1096..2718)
                     /locus_tag="JX887_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1258210.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            2967..3488
                     /locus_tag="JX887_002268"
     CDS             2967..3488
                     /locus_tag="JX887_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258211.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(3674..5404)
                     /gene="spxB"
                     /locus_tag="JX887_002269"
     CDS             complement(3674..5404)
                     /gene="spxB"
                     /locus_tag="JX887_002269"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAX1258212.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5569..6387
                     /locus_tag="JX887_002270"
     CDS             5569..6387
                     /locus_tag="JX887_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAX1258213.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6490..6687)
                     /locus_tag="JX887_002271"
     CDS             complement(6490..6687)
                     /locus_tag="JX887_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258214.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            6856..7434
                     /locus_tag="JX887_002272"
     CDS             6856..7434
                     /locus_tag="JX887_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAX1258215.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(8479..8982)
                     /locus_tag="JX887_002273"
     CDS             complement(8479..8982)
                     /locus_tag="JX887_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAX1258216.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9341..10366
                     /locus_tag="JX887_002274"
     CDS             9341..10366
                     /locus_tag="JX887_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAX1258217.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            10689..11567
                     /locus_tag="JX887_002275"
     CDS             10689..11567
                     /locus_tag="JX887_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258218.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
BASE COUNT         3591 a         1973 c         2256 g         3770 t
ORIGIN      
        1 tgattagaac ttgcgaaaat aaaccggtta aagtgtgtct agcgcaagag atttgctata
       61 atagacgata agggtaaaat gtaacgagaa ggggttgaaa aatgtgtatc aaattgtaac
      121 agattcttgt tgtgatctgc cataccatgt attagcaaaa gaaaaagttg attttttatc
      181 aatgaatctc caattgaatg atcaagagtt agtagatgac ctcggaaaga cattcaatta
      241 tgaccgctac atgaatcagc tgaaaaatgg tgcgatgcct acgacatcac aaatcaatgt
      301 tggccgatat ttagaatttt tccgttctta tgcggaaaaa cagattcctg ttttatatgt
      361 ggctttttcc agtggattaa gcggctctta cagtagtgcg cttcaagcgg ttgaattgct
      421 gaaggaagaa tatgaagacc ctgagatcta tgtttttgat acaaaagctg caagtattgg
      481 ggaagggctt ttagtattgg aagctgtaag attgaaaaaa gaaggtaaaa gcatcgaaga
      541 aaccctagag tggctggaaa gtaattattt gaaagtccat tcatgggtaa cagtagacga
      601 tctgaaatat ctagaacgag gcggtaggat ttccaaagca agtgctactc ttggcagtct
      661 attgagtgta aagcctatta ttacggtgga taaagaagga aggctgacga atgttgacaa
      721 agttcgagga agaaacaagt cgatccagac aatcgtcaat gagacggtaa aaacaatcgt
      781 tgcaccactt gatcaaatcg tttatgtggc ttacgctggg gatctagaga gcgcggagaa
      841 ggcaaaacgg cttttggaag agcagataaa gatgaaagat gtgaagcttt atcccttagg
      901 accaacgatc gccagtcaca caggctatgg ctgtatcgcg attttttcga tgggaatcag
      961 tcgataaaag cagtaactca ttctgtaaaa aagcccagaa attgattgta acaaaaacag
     1021 cgactcttaa aagatagatg agcatcctat ctcttagagg tcgctgtttt tttatttttt
     1081 aagctaaata ggccattatg cccataactc gttcaattgt ttttgaatat ctgcattttc
     1141 caaaaattca tcatatgtcg tatcagctcg atcgatcaca cctttatccg aaacggcaat
     1201 gatgcggttt gccaatgttt ggataaattg atggtcatgt gacgcaaata agattgagcc
     1261 agtaaatgcc atcaagccgt cattcaatgc tgtgattgat tctaagtcta aatggttcgt
     1321 tggatcatct aatacaagta cgttagcttt cgaaagcatc atttttgaaa gcatgcaacg
     1381 gactttctct ccaccagata aaacattcac tggtttcaat acttcttcac cagaaaacaa
     1441 cattcttcct aagaagcttc ttaagaaggt gttatcatct tcttctttac ttgcatattg
     1501 acgcaaccag tctaaaatcg ttagatcagt atcgaattct ttcgttgtat cctttggtaa
     1561 ataagaatta cttgttgtca caccccaacg tactgttcca gtatctggcg taatttcacc
     1621 catgataact ttgaatagcg ttgttgttgt tatatcattt tctgcgacga aagcgacctt
     1681 gtcttctttg ctcaaattaa aagatatatc atctaaaatt ttctttccat caatcgttac
     1741 acttacattt tctacctgca ataagtcgtt tccaatctca cgttcaggtt tgaatccaac
     1801 gaatggataa cgtctagaag aaggttggat atcgtctaaa gtaatttttt caagcatttt
     1861 tttacgtgaa gttgcttgtt ttgattttga tgcattcgca ctaaagcggg caataaattc
     1921 ttggagttct ttgatttgtt cttctttttt ggcatttgcg tttgcttgaa gtttagccgc
     1981 tagttgacta gattccaacc aaaaatcata atttcctaca taaagtttga ttttaccaaa
     2041 atctagatcc gccatatgtg tacatacttt gttcaaaaag tgacggtcat gggatacaac
     2101 gatcacagta ttttcaaaat tgatcaaaaa ttcttccagc caattgatcg attggatatc
     2161 cagaccgttt gttggttcgt ctagcaaaag aacatcaggt ttaccaaata gtgtttgtgc
     2221 taataacact tttacctttt gtccaccagt taattcactc atttgctgat ggtgcaattc
     2281 ttcagggatg ttcagacctt gcagtaaaac agctgcttct ggttcagctt cccatccatt
     2341 aagctcagca aattctcctt ctaattcagc tgctcgaata ccatcttcgt cagtgaaatc
     2401 ctctttcatg taaatcgcat ctttttcttt cagcacttca tacagacgct tgtgtcccat
     2461 gatgactgtt tcaagtacag tatagtcttc atagtcgtaa tggttctgtt tcaatacggc
     2521 catccgttca tctggtccca tagtaacgga acctgtggaa ggctgcagat cccctgataa
     2581 cactttaagg aacgttgatt tacctgcacc atttgcacca atcaagccat agcagtttcc
     2641 gggggtaaat ttaatattca catcatcaaa tagtttgcgg tctgaaaagt gcaaactcac
     2701 atcatttaca gtaatcaatt tttttcctca cttttatcat tattagtttt gacaagtctt
     2761 atagaattat ataggggaaa ggtaaaagat tcaaggcaat cgaacattct ttgtgtttca
     2821 cgtgaaacag aatgaaaaaa ataaaaataa aagcggagcg aaaatagcta ctataggatt
     2881 tattagtttg caacagcata atttttgacg ttatttataa gagggagtac tataaaactg
     2941 taaaagaaat gaaagaagga ttgaaaatgg atgaaaaaag aaccatcgac tggggctcat
     3001 tgattttggg aattttattt gtacttgtct cattgttatc atttcaagac cctgtcggaa
     3061 atttagttgc aattgtagta gtctttgcga tttttgcctt tattaaaggg atatttgaac
     3121 tgtttgtacg gaacagatta aaagagctaa caggatataa aggaaagatg cccttaataa
     3181 tcgggatcat cgatattcta gttggcgtct ttttcttatt caatattggt gcaggagtcg
     3241 cagcattgcc ttttgttttt gcagtatggt ttattgctga ttcagtttta gcgttattta
     3301 ctgctgactt ggcaagagga gtaagtgaag gatattattg gtttacgatc atcgtcaata
     3361 ttttaggaat tttattagga attttcttat tgtttaatcc aatttcttct gcgttgacat
     3421 taagcttttt agttggattc tattttatgt tatttggtat cacacatatc gtctatgcat
     3481 ttagataagt aaaatcaaac aaataaaaaa gccggcttcc gattacagtt ttactgttgt
     3541 aattggaagc cggctttttt atcatggaca aatatgcacg aggtgatttt taggtgtcga
     3601 gacaaattta tgcaaaaatg tgagaagcta tatacacaaa ttttatctta atactcgaag
     3661 catagcgcag ttgtcacaac ctcttttcat ataattcatt caatactggc aaatcatgga
     3721 cttcatattt ttctttgaat gcttggattt cttcttcaga atattttctt ggatctaaat
     3781 gcagatcttc tactggcaat gggcgcttgt tattgatctt cacatcgatt actacaggac
     3841 gatctgattt tgcagctgca tcaaaggcaa atcgaagttg cgagtattct gtgactgtaa
     3901 agctatttgc cccgagcgct tctccaactt taccgaaatc tgcatcttct aaaaatacac
     3961 caaatttctt ttgttccgta tcttcttgtt ctgcttcgat gaaaccaaaa gaatcattcg
     4021 aaaagacaac attaataatt ggaagctgat atttgacttg tgtaatgata tcttgcatga
     4081 ccatagcaaa cccgccatca ccacttaagg taaatacttg tttttctggg tagcttagtt
     4141 gtgcggcaat tcctcctggc acaccattac ccatagttgc gaaccatcca gatgtcgtat
     4201 gtttttgttt accgttcata ttcaataaac gaatagaatg gatagtcgtg ttaccgacat
     4261 ctgtgacgaa aatcgcatcg tcttcagcaa tacgattgat ttctttatag acagcctctg
     4321 gacgaatcgg ttcttcctct cgatcttcaa aagatttcaa ccaatttacc catttttctt
     4381 tattttcttg atttgctagg taccagctat cagcagggcg agcatcccct aactcgacaa
     4441 gtctttgcaa agctgtgttt gcatcaccga ggatcgacaa agatgtttca tggcgtcgtc
     4501 caaattttga cgcatcgata tcgatttgga taaattcagc agttggatta aaaaatgcac
     4561 gtccaaatgg gaagtcgcta ccgacaaata agatcagatc ggcttctgcc aatgcttcat
     4621 ttccgggttt agtagcgaca cgtccagcaa aaccaagaaa gttttcataa tcatcaggaa
     4681 taattccttt tgctagaacg gaagcgacaa caggaactga aaaatgttct gagaattctt
     4741 tgatttgcgg aaatccgttt cgcgttcctt gaccaacata aagaactggt ttttttgctt
     4801 tttcaagata aggcaaagca gctagcaaat ctttttcttc tggtaatatc acacttgttt
     4861 tgtgagtgtg agcggtggag aaaggttgtt cgtcaatttc ttcaaaacca agatcaacag
     4921 ggatagtcac gatagccacg cctttatgct cataggcggc tttaatggct tcatctacta
     4981 catgcggaag actttgtggt gtcatgactg tacgattgta tacgctaaca tctgcgaaaa
     5041 taggattttc atttagttcc tggaaagagt tatagttcat ggatgtagaa gcaacttgtc
     5101 ctaagaacgc tactagaggc acatggtcca tctgtgcatc atacaaacca ttgatcaaat
     5161 gtgtcgcacc aggtcctgca gagccgaaga cagcgccgac tttccccgtt aattttgcat
     5221 ctgcagcggc tgcgagtgcg ccgacttctt catgacgaac ttgaatgtag ttgatttcgg
     5281 ttttttcttg atatagcgca tccataattg aattgaaaga tcctccggga atgccgtaaa
     5341 tatggtcgat accccagctt tcaagaactt ttaccattgc gattcctgca ttgatttttg
     5401 acatggtgtt tcactccttt agcaatgatg atacataaat tttttgtatc tagagtatag
     5461 aactttttat cgaaaatccc aactaattcg tcttttcaca aaaatgtagt catgtttttg
     5521 ggaatatgct agagtagtac atagatagat tcaagagagg ggaatggcat ggttgaatgg
     5581 ctattgagac ttgaaccttg gcagcaagca cttgctggga cagcttttac ttattttatg
     5641 acagctcttg gtgccgggtt ggtttttttc tttaaagaaa tcaaaaaaga agtgctaaac
     5701 ttgatgttag gatttgcttc tggtgtcatg attgctgcaa gtttttggtc tttgttagat
     5761 ccggctatta caaaagcaga agaaaatgga gatattgctt ggctagttgt aagtattggg
     5821 tttggtttag gcggtgtgtt tttatatatg gcagataaaa cactgcccca tatgcatttt
     5881 ggaccacaac atgaagcaga aggattgcct acccatttaa aacggacgat cttgcttgtt
     5941 ttttctatta cattgcataa cattcctgaa ggtttagccg tgggggtagc attcggtgca
     6001 gcagcaactg cggataatcc gacagccgct atattagccg ctgtttcggt ggcgctaggt
     6061 attggtatcc aaaacttccc agaaggagca gctgtatcaa tcccgttgcg acaagaaggt
     6121 ctgagtcgta aaaaggcctt tgtttacgga caagcttctg gaatcgttga accaattgct
     6181 ggagtgattg gagcgctact agtaacgaaa gtggagctgc tgcttcctta tgcacttgct
     6241 tttgccgcag gagcaatgat ttatgtcgtg gtggaagaat tgatccctga agcacagcag
     6301 acattgtcca gcaaacatca ttttgcagtt tttggcgtca tgagtggatt tatcattatg
     6361 atgattttgg atgtggcatt aggataaata aaaaaaatat atatgatata tcaaataggg
     6421 ccgcgaactt atatcgcgac cctatttttt tagtaagtta tatcataatg aagtgaatgg
     6481 tatcatacat taataatagt tttttctatg tgtatttcct ttgatccagc gaacaagcca
     6541 gatgataagt gcgattggga ttagaacttt gaccgcaaac cataaaagcc cgcttaggac
     6601 actgacaaaa agactgatga cgaagctagc tgcaattagc actaaaagaa ccatgaagat
     6661 atttaagaac atattttttt gacgcataca aaaccctcct cttgttcatt ctttactata
     6721 gaaaaagtat aacagggatt gtttaaaaac acctccaact gaagactgat ttttacttca
     6781 tctacttaaa tgatcaaaca attgcttttt ctctggttta tcatctaaaa tagagcggaa
     6841 aaggaggaga atatcatgcc taaaaatcgt cttgaagcat ttacagatgc tgtaatcgcg
     6901 attatcatga ctattttagt tttagaactt catgaaccta acggagacac gtgggaggcg
     6961 ctcgctgcat taggttaccg attttttatc tatattgtca gttttatcat tttagcgatt
     7021 tattggaaca atcatcatca tttatttcaa gttgtacata agataaatgg acgggtctta
     7081 tgggcgaaca gtttctttgt ttttgcgctt tcgctttttc cgtttgcaac ttcatggatc
     7141 agtgagtaca tcaatagcct ggctccagaa atgacttatg gttttgttac cttgaccgct
     7201 aatattgcgt attatatctt ggcaaaagaa cttgtcaaag caaataaagg ccacgagaaa
     7261 gcattgaagg cgatgttgaa taattacaag aaatcgtatc tatcgattgg tttgaatgtg
     7321 ttaggaattg tcttagggta tttagtagcg ccagtagccg tgctgatcgc aaacatcgtg
     7381 attctagctg cttggatcat cccaagtcgt accatcgaat cacaatatcg gtaaaatgat
     7441 ccgtgtttaa aatttaagag aaaaatatag aaaaaataaa taaacgatca aatatccgag
     7501 tgatactagt attcaaagag ggatgcagat ggatcaaaaa agaattcatg taggactgat
     7561 tactagtttt gtcacgatgc ttatttattt ggatcaaggt catttgactt ggacagtagt
     7621 tggtgtcgta ggatttttga cattattcac agcaataaaa aaataaacat ctttatgtaa
     7681 tctgatgttc tatctattta agaaaagcat gtttacagca gtatgattct gttgtaaacg
     7741 tgtttttatt tgtggaaaat ttaattttta gaaaagtgta tcgaaaaata gatagttagt
     7801 ttttccacag tggataactt cgtaagagat aaaaataaaa aattagtcaa agaagggcgt
     7861 atagatttct tttgatagga gatatacaac agaaatgaat aaatattaac gtgttttcaa
     7921 acagtataaa acggtgtggt ttttggaata aaaaaataac atatctcatt ttacactttt
     7981 gttattttat acttaaaaaa taacgacaca gaaaataccg tgtctcagat ttctctacta
     8041 cttctaaaaa ctactgtttt tttcctttga aatgccttca aaaagtagga tcaggcagaa
     8101 tatactggca gaatcaagga gaagggagcc taaataagga gaaaaaccat agaaaatata
     8161 aagtaattac ttataaaaca agctttttat agaaaaataa tatacctgag tagggtataa
     8221 attaagacgg aattcctttc tagattgaga tattgactag gaagaatgtt aagattttaa
     8281 gcctttaagc taaaaaaaaa ccctttttgt taaataaggg gaatatagcc tgtcagtttc
     8341 aaactgcaag tcgtcctgct gcaataatat agtagattag agatgaaaat agattttttt
     8401 aaaccaatga ctgaataaaa agaccgtcat agatacacat tggaatgtgt ctattacggt
     8461 ctttttttac gaacgatttt attgaagacg gacagttcgg gtcaaaaata aaaaagctac
     8521 gatcagaaat aagaataaaa tgtatcccaa aataatggct agacggtcta acttatttgt
     8581 cgatagatgt ttgtttagaa gttgataggc ccataaacct atcagtcctc ctgttgtatt
     8641 agttatcaaa tcagtgatgt ccgctacgcc aataccgaat aggaattgaa tcaattctgc
     8701 caagaagctt acaaggaaaa taatccctaa ttttttagaa aaagaaagtc tcttgaaatt
     8761 gacattcaaa agcaccccaa aaggaaaaaa gacaatcaag ttataagtgg tctcacgtaa
     8821 taccgtcgta ttttcaaaag aaaaagtaga aaaagggacg agattgacat tgctgtaaga
     8881 ataagtgaga aattgtggaa gattaaatga tagcttgaat aaaatcaacc ataatagaaa
     8941 gaataaataa atccctaata aaaattttga tacataccgc atagacatct cctccattta
     9001 aaaagtatac catcgaaaac cgctgaaaaa tcataaaaaa gtatgaagtt taaggaccaa
     9061 cgtagttatc gtacgaaaat tagaagcttt tttttgttgg gaatccggtt tctttaacaa
     9121 agctaagata gcgagttgct tggaaaagtt gctatctttt ttctgtcaaa acgactcgga
     9181 atgttcgttt tttgttctaa tttctccaag ttgtttactt tttgatacta agtttatgaa
     9241 aaatcaagaa atagttgtta tactaggtaa tgctgacaaa cgggattggc atttcatctt
     9301 ggttcagctt tttttccaat tactaggaag gagggataga ttgttcaaga cttattttcg
     9361 tttcaataaa atacaagata atccttttcg tatcatgaat ctgatgctac ttatctttat
     9421 tgtattatgg ttaggttaca taaatcatga ttttttgatt tcaagttttt catcattagg
     9481 gatctttact tttttctatt atcaaaacat accgatgaaa tatttgctga aacgtatgtt
     9541 tctgatcggt tgcggactgt tggttgcttt cgttttgggg atcttatcga cttatgtttt
     9601 atggcttgaa ccatttgccg tagctttggt tgctttttcc agcagattcg tgttgcgatt
     9661 attccatatt tctaaaccag gtggcttgtt ttttgcgatg ctttctgcca tgggaacgag
     9721 catgcagctg ccaatcgctc aattaccgat cgtctcactt tattttttta tgggtgtcgt
     9781 ttttgccctg attgcggcag tgattacaaa attactggat tcacggcctg agcagacaat
     9841 tgaaaaagca actttaaaag aaagatttca cgaagagcct ttagtgatca ttgattctgt
     9901 tttctacagc gctgccttat ttctttccgt ttatgtcagt cacggcttga atctgcataa
     9961 tccttattgg ttgaccttgt catgtgcatc gattttgcta gcagaaaact tggatgcgat
    10021 gaagcatcga caagtccaat atctgattgg atcgatgggt gggttatgtg tgtcggcatt
    10081 cttgtcattt gtgccgttta cgcagttgca gaccattttt ctgatcactt ttctatatgg
    10141 aatcgcacaa tttctagttg ctagaaatta tgcagttgct aatatttttc ttaatccgat
    10201 ggcgttgatg ctatctacac ttattcgtgg agcatacttg atttctttga tcgaatatcg
    10261 ttttttaggg atcgtcatag gaagtttcat cggtttaggt gttgcgtggg taatgacggt
    10321 tggtttgcaa cattatttaa cggttgttcg tcaaaaatta gaatagaagg acaaatatat
    10381 gtgccaaaag aggttatgac aagatttttg tcacaacctc taattcaagg tgttcaaaag
    10441 ccagattctc agcattaagt caaattcaca caaaaatgtg gaaaggaact ttcaaaaaaa
    10501 ttttatattt attctatcaa aaaattttgt ttatgatggt aactgaataa actttcctga
    10561 gatggtcaat gctttccttg aaagtcttac agatattctt tcttcataga aagtttaagt
    10621 tttatagtta gtgtacaata aaagtatgtt tataccatat ggtgtccgga taatcagtca
    10681 tttaaacaat gaggttcaaa gatatgaaaa ggggaaattt gatgaagaaa ataagcaatg
    10741 aaatccaaat tctggcagaa actttaactc ttcccaaagt cgttatagag caaatgattg
    10801 tacaagcaaa aaacatcctt gatgaggtgt ttgagcaata tagtcatgaa ctaatggatc
    10861 ctaataaagc aaaggcgact gcaaagaaaa tagacaaagt ctatgaagag gaaccttttg
    10921 cagcattagc tatttatcta tatgcagctt ctcaaagttg gaaaaaaatt tatcaaccat
    10981 tgaagattcc aagaactatc tatttggcaa caatgaatgc ttttactaga tttattcatg
    11041 aacatttcca agtaacagga agctatcgct ttgaccgtgg tttttggatt tggcattaca
    11101 ctagtggctt gatctttcgg attggtgaat tggagtacga aatgacatat tttccgaaag
    11161 ggtacacgga tctaagatta gaaggaaagc agtgcctttc tcttcatatt ccttccgatg
    11221 cagatttatc tcagaataag ataagagata gttacgaaag tgccattcgt ttttttgaac
    11281 tttattttcc tgattaccat taccaagtga tgtacacaga tacttggtta ctatcaccca
    11341 atcttactaa atggttgaaa aaagagtcaa aaatctgtct ttttgcagcc gattatcgat
    11401 tattatcagt tgatgaacag gacgatagtg gagtcccttg gatctttgga cgagtagatg
    11461 cccaaataca tgattatcca gaaagtacga gtttacagcg acaagcaaaa gagcaattgc
    11521 ttgcaggcga gcacattggc tctggcttag gtattcttac ttcataagtt tagtacttcg
    11581 aaatagttta
//
LOCUS       DADGHT010000092        11486 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.093, whole genome shotgun sequence.
ACCESSION   DADGHT010000092 DADGHT010000000
VERSION     DADGHT010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.093"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(118..432)
                     /locus_tag="JX887_002276"
     CDS             complement(118..432)
                     /locus_tag="JX887_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAX1258219.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(446..706)
                     /locus_tag="JX887_002277"
     CDS             complement(446..706)
                     /locus_tag="JX887_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAX1258220.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            876..1190
                     /locus_tag="JX887_002278"
     CDS             876..1190
                     /locus_tag="JX887_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAX1258221.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            1192..2847
                     /locus_tag="JX887_002279"
     CDS             1192..2847
                     /locus_tag="JX887_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAX1258222.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            2930..5065
                     /locus_tag="JX887_002280"
     CDS             2930..5065
                     /locus_tag="JX887_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1258223.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            5240..5749
                     /locus_tag="JX887_002281"
     CDS             5240..5749
                     /locus_tag="JX887_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258224.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            5746..7050
                     /locus_tag="JX887_002282"
     CDS             5746..7050
                     /locus_tag="JX887_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAX1258225.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            7146..8015
                     /locus_tag="JX887_002283"
     CDS             7146..8015
                     /locus_tag="JX887_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAX1258226.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(8127..8447)
                     /locus_tag="JX887_002284"
     CDS             complement(8127..8447)
                     /locus_tag="JX887_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAX1258227.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            8601..8996
                     /gene="dhaM"
                     /locus_tag="JX887_002285"
     CDS             8601..8996
                     /gene="dhaM"
                     /locus_tag="JX887_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAX1258228.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            8998..9981
                     /gene="dhaK"
                     /locus_tag="JX887_002286"
     CDS             8998..9981
                     /gene="dhaK"
                     /locus_tag="JX887_002286"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAX1258229.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            10009..10614
                     /gene="dhaL"
                     /locus_tag="JX887_002287"
     CDS             10009..10614
                     /gene="dhaL"
                     /locus_tag="JX887_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAX1258230.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            10761..11426
                     /locus_tag="JX887_002288"
     CDS             10761..11426
                     /locus_tag="JX887_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258231.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
BASE COUNT         3880 a         2043 c         2432 g         3131 t
ORIGIN      
        1 acttgatgca ggacagcgtt ttcacaacct ttgattcacg gttttccaga agtagcttct
       61 tcgaaaaata agccgaaatt tcttgaagct gatcacttct gtcgcaacct ctactgacta
      121 aggcttgata taagcataac cttgggattg cagttcaact aaatcaagga cacctgctgg
      181 tacaacgatt acttgttcag gtaaagaact ttctgaaata tgattagcac gcatagcatt
      241 ggcgcaagcg tgaaaaacga ctccttgcaa atctaagaat tctgcattgg cagagtctag
      301 ataaccggta atcgcgatgc catttacaga tacgacaatc gtcgtttctg gagaagcttt
      361 tatcaggttt tttacgtttt tccctgtttc tgaccatttt tctaattcat caatatggaa
      421 aacgactttc attgaaatca ttcctttact ttttaataat catcttgatc gcttgttcta
      481 gtttagccgc ttgttcttct ggattactat caggtttctc aaagcaattt ttcagattat
      541 ctgcaacgat catgcccatt acgcgatcaa tactagaacg aacagcgctt aattgagtga
      601 tgacatccat acattctttt tcgtcttcga tcattttttg gataccacga atttgtccct
      661 ctgtacgttt caaacggttc aggatatttt tattatcaat ctccataaca cattctcctc
      721 tatttttata attagataat accccttatc ggtattttat gcaaatataa aaagtagtga
      781 aaaaaatgaa gagtcattct ggttgacata ttaataaagc tcctgtttaa tataccccat
      841 gaggtattta taaaaatgta aatgaggtgc agaaaatgaa tttgctattt caatcaataa
      901 aatcgataac agtcccagaa ttaaaggaaa agcttttgga aaatccagcg ttacttgatg
      961 ttagaacacc tgcagaatac cggggcgggc atataaaagg agctaaaaat gttccattac
     1021 aaagtataaa cagatatgat ggagacaaag aaaagaccgt ctatgtgatt tgtcaatcag
     1081 ggatgaggag taaacaagca gctaaagaat taaagaaatc tggttatgat gtagtgaatg
     1141 tacgtggtgg catgaatcaa tggtttgatc gaacagtagg agggaaataa gatgaaaatc
     1201 gttattgtcg gaggtgtagc aggtggaatg tctgctgcta cacggcttcg ccgattaatg
     1261 gaagatgcag aaatcgttgt ttttgaaaaa ggaccgtatg tttcttttgc aaattgcggc
     1321 ttgccttatt atctttcggg agaaatcagt gaacgggaaa atcttcttgt ccaaacgcca
     1381 gaatcattat ccgctcgttt ttgtttagat gtgcgtccaa atcatgaagt gacagccatc
     1441 tttcccgaaa acaaaacggt agaagtcgta catgagggtc aaaaacacat tgaacagtac
     1501 gatgcattgg ttttatctcc tggtgcaaaa ccagttgttc catcgattcc agggataaca
     1561 gaagccgaca atgttttttc tattagaaat gtaccagata tcgataaagt gatgcatgca
     1621 ttagaaaaac agccaaagcg tgccgtgatc gttggtgcag gattcatcgg attggaaatg
     1681 gcagaaaacc taaaaagaag aggtttagaa gtcatggtga tcgaacaagc accacatatt
     1741 cttccaacac tggatgaaga aatggcagct tttatagaaa aagaattgtc tcatcaagga
     1801 gtagaagtga ttacttctca tgctgtcgct ggatttgaag accacgggaa acgattgcga
     1861 ctggatgatg ggcgtaccat ccctgctgat ttagttattt tatccattgg tgttcgtcct
     1921 gataaccagc tagcagtgac cgctggaatc gaattaggca tacgcggggg tatcctagta
     1981 gacgaacgtt atcaaacgaa tattcctgat atttatgcgg tgggggatgc tatcgttgta
     2041 aaacagcaaa tcactggaaa agatgcactt atttctcttg cttcaccagc caatcgtcaa
     2101 ggtagacaag ttgcggacac gatttccgga atttctcgaa gaaatcaagg cggtattgga
     2161 acagcaatta tacgaacgtt tggaatgact gccgcatcca ccggtttaag tgaaagaaca
     2221 gccaaagaaa acgaactgtc ttttgaagtc attcatgtat caggaaaaga tcatgcaagc
     2281 tattatccag aagcaacaga tattttactg aagttgatct tccatccaga gactggcgag
     2341 atttatggtg cacaaggtgt tggggcaaaa ggtgtggata aacggatcga tattttagca
     2401 acagcaatca aagggcattt gacgatcttc gatttaccgg aattagaatt gacgtatgca
     2461 ccgccatttg gctcagccaa agatccagta aacatgctag gatatgcagc aatgaacatt
     2521 gcagaagggc ttagtgaaac cgtacaatgg catgaattgc cgacagaact agcaaaagga
     2581 aaaattttat tagatgtgcg aacagcagaa gaattggaaa agggcaaatt caaggaagcc
     2641 aaacatatcc ctttgaatga acttcgggac cgattaaatg aattagacag ccaacaagaa
     2701 tatatcgtca gctgtcatag cggattacgt agctatctag cggaaagaat cttgaagcag
     2761 tctggctacc acgtaaaaaa ccttgatggt gcattttctt tatatcaaac tgtccgacct
     2821 gaagaactga tatatcctaa caaatgatac tcgttaaaaa gcttgcattc gactcttaaa
     2881 agaggtaaac taatcggttc caccacttta aaaaaagagg agaatgtgta tggtcaacac
     2941 acaaaaacag ttagaagaag catatctgaa gaacgtgtat caaaagctaa ttgataaaaa
     3001 aaacgaactg cgggaatcga tggatacggc aaaaatagaa ggaaaccagt cgttgaaaga
     3061 aatggctggc gagcttcgat tgaattttga cagttactta gataacctgg atactttttc
     3121 gatgattgaa atgaaaaata gagaaatcga tcagatgaat atcaaacaga aaaacgcaga
     3181 aaatcagcta gcaaagatcg aacgtttatt gaaaagtccc tactttggaa aagtcgttgt
     3241 agactttctg gataatgagc caaaagaatc cttttatatc ggtacagcaa atttcacaga
     3301 tgatgcagat gaaaatcttg tttatgattg gcgttcacca attgccgaac ttttttacaa
     3361 taacatgatt ggtccatctt cttatacggt tcgtcaaaat aaaatcgata cggttattaa
     3421 agaaagacga caatttcttt tggaaagaga tcgtttggtc aagttttttg atacgtctgt
     3481 agctattcaa gatgacgtat tattagaagt cttaggccaa gatgagacca atgaaatgaa
     3541 ggctatcact gctacgatcc aatcggaaca aaacacaatc attcgggatg tgaaaagtca
     3601 aaatatcttg gtaaatggcg tagcaggaag tggtaaaacc tctgctatca tgcagcgtat
     3661 tgcgtatctg ctctatttat atcgagatac gatgacatcc gatgacttgc tgattctatc
     3721 acctaatcat cggtttatcg actatatttc gaatgtccta ccatcattag gtgaaagaaa
     3781 tccactgaat ctaaccatca tacagctggt ttcacagctt tcagcagagg aaatagaagg
     3841 tgaagaggct tatttcaaac gtatcacggg agaaaatgta tcggagcaga cagaacgttt
     3901 gcgtagcaaa aagtttatcg ataatctaaa acaatcagat cctttgtttt tagatcatcc
     3961 gaattttatc cgtggactta ctaaaaatgg aaaaacagtc ctttctaaaa aaacgatcga
     4021 aaaaatatat gagaaagttc ctgctcatcc taaattgatc gataggcttc aagcaacgaa
     4081 aaaggcactg atgagcgaat ggaagaatca tcttttgaaa caagcaaaaa gtcctgctgt
     4141 gcagaatcag gtactctcgt tgacagaaga taggcagttg gaattattcg gtaaattgat
     4201 ttctgatgat tcggaacaaa gtattgtagc ttatgcaagg aaacttttac aaaaaaaata
     4261 tcgaaaaata accagacaaa tcgaagaaat ggcatgggtg gatgagcatc agttgtttga
     4321 aagaatttat gaaaaacgat atggctcagc ttatgcttgg caacccacac gtactgttga
     4381 tgaagcagtc attatattag ctattcgtca tttacttgtt gaaaaggtaa atgtaccagc
     4441 atttcgctat ctattgattg atgaagtaca agattatacc ctggcacaat taggtctatt
     4501 gatcgaatta tttccaaaaa ctcactttac tttagtaggt gacgagaatc aggcaatctt
     4561 taattcttcc actacttttg ctgatattat gcgttgtttc gacgactacc atctgccgat
     4621 ccatcggtat gatcttagaa atagttaccg ttctagcgga gcaatcacag agcttttcaa
     4681 aacctatgct gtggatcaag agaagatcga catcgtatcg atccgaccgc aaggaaaaga
     4741 acccgaatac cgctcttttc gatcctctga agaattgttg aaaatactag ctgagatttt
     4801 ggtttctcta aaaggagaaa aagcggcagt tatcacccaa acagaagagg aaacccaaac
     4861 gctacaagaa tcgattaaaa aaaattcata tggattagaa aactgccaaa tcattccttt
     4921 gagtctagca aaaggactgg aatttgatca tgtaatctta tatccatttg aaaacgatgg
     4981 agatgagcaa agaagacgca gacaaatgta cacggcgata tctagaggaa tgaaaagcat
     5041 tgtcgtattg gaaagagcaa cataattaag agataaaaaa taaaaagaac aactgataaa
     5101 aagaacaaaa tatttttcat ttgctgatga gaaatgtttt gttctttttc ttaggaaaaa
     5161 tttaggaaca ctttatgtga aaagaaatga aatgtatggt aaactcctac gtcgtaacaa
     5221 aaaaacgtga ggtgaggata tgaaaaaagt aacaagagaa gaagttgcat caattttggt
     5281 gaaagataag tatttttcaa aaggtaatta ctggttaaag atttggcaaa cgttagtggc
     5341 tcttttagga tggatgatcg ttgttcttcc ttttatatgg gtctttttcc cattaacgag
     5401 accagaaaga gccaaggatt tttccttgta cgctttttta tcagaaaaga aaatgctgta
     5461 tttcttaatc ggcttttttg tattgatttt tttcagtttc ctgattacct catttgtatt
     5521 gactaggtgg aacaatcgaa atctatacaa aaaagtaaat aaatcttttg aatatgaaga
     5581 tgaaaaattg aaaaaaagac aagaattact tgaagaagtg tatacggaac gttttggaac
     5641 aaaagaagag agagaaacgg tccgttttta ttctgtctcc gaagagaaaa atctagatac
     5701 gacattcatt gcagatttgt ataaagaaaa tggggtggaa ctgaaatgat ctcaatcacc
     5761 catacaggta atttattctt agatacttgt ttgtctatta tgtatttttt tctcgtttct
     5821 tatccgattt taggcggatt tgtatggttt attggtgtct ggtgttatgt gtttttatac
     5881 aaacataagc aaaaagaatg ggtagatgtt cccttgagtg tcgaaccgtt catcacgatc
     5941 atggtgccag cccataatga agaaattgtg atcgaatata caatcgagta tttgatgacg
     6001 aaattgaatt atcacaacta tgaggtatta gtgacagacg atggttcaac ggaccaaaca
     6061 ccagaaatat tagctagact gatgaaaaaa tacgctaatc ttcgtgtggt tcggatcgaa
     6121 aaaaataaag gaaaagccca cgcgtttaat atcggacttg cctttgcaaa agggaaattg
     6181 attttaagca atgatgcaga cacggtaccg gagccagatg cactgattag gtatgtgaat
     6241 tatttcattc gccctggtgc aagacatatt gctgcggtca ctgcaaatat ggatgtccaa
     6301 aatcgtacca aattgattgc aaaatctcaa acggttgaat tctcaagtat cgtgggcatc
     6361 attaaacgaa cacagtcagc tgttttcggt ggtctttatg cgtacagtgg agcaaatacg
     6421 atgtatcgaa aagaagcctt gatcgatgtg ggcggattca gacaagatcg agcgacagaa
     6481 gacatcagta ttgcttggga tcatcagtta aatgactggt tatctgtttt tgctcctgag
     6541 attatctttt tcatggaagt acctgtgacg ttgaagatgc tatatcgaca cagaaaacgt
     6601 tgggcaaaag gtggaacaga agtctggctg acgaatttca aaaaagtgat gctccatcct
     6661 tttaaacata ttggaagaac gatcatcttc attgatcaaa cattgagtat tgtctggtca
     6721 atattctttt gtatttccgt agttcttttt gctggattaa tcgggcatta tgtatatcaa
     6781 ggaaactacg aacagattta tattactttt acattcagtt ttgtgttcat ctgctttgaa
     6841 atggtcgcag gatttttcca gttgctagct tcgctgattg tagatgatcg acgaagaaaa
     6901 ttgaaatacc ttcttttcgc accactatat atgcttttgt tctggatagt gaacgcgata
     6961 acgatcgtga cgactttcat tccagcagtc aaaacgattt taggttatgg aagcgggaca
     7021 tggaaaagcc cggaacgtac aaaaaaataa aagatgcacc gttttttaga caaacagcct
     7081 gttgtgttta tggttcttcc aaacattttt gcttataata agaaattagt taaaaagtag
     7141 taaggatggg aaaagtgatg aaaaaaagaa tgaagccgtt aatctggcca attgctgttt
     7201 ccagtatttt cttattggga cagacagctt ttgcggaaac ttctgaacct gctcaaacag
     7261 aaccttcaac aaccataagc tcttctggtg ctgaaaacgg tgcctcggaa acagaaatga
     7321 cttccaatgt accgacagat aattcaggag aaacgatttc atcttcagaa gatacatcaa
     7381 taaatagttc tacctcttct gaccaaatcg atcatttgca agacttggaa aataaaagaa
     7441 aagaactcga agaagcatta gaagctgcaa aaaacaaatt gaaagaagac caagcagcaa
     7501 tcgatcaaga tttagctgat cttaaaaata aagtgggaaa tgaccgtgca caacttgaga
     7561 aaaagcttgc cgaagcgaaa gcaaaagcgg aagctgtcca aacagatctt gacgggaaga
     7621 tccaacaagc aaaagaattc aatcagcaat taaatcaggt tgctcaaaca gcttctggaa
     7681 agctaagtca aactcaagcg gatatcacag cggccagtca agcaatccac ggaaagatca
     7741 gcgaagcaca aacagttgct aatgattttg aagcaaaaaa agctgactta gcagctagtt
     7801 tccaacgaat aaaagatatt ttgcattcgg caggagaaaa atcagtgacc tctggaagca
     7861 cgacagaaac agttcagcaa acgacagagc catccaaatc aacaagtcag actttgccaa
     7921 aaacaaatga aaaaacagct tctgtcagtt attccttagc aggggcgggt gtgttagtcg
     7981 cagcagctta cggaatcatc cgcaaaaaga aataaaaaag agaggatggg aaggtagagt
     8041 acctcgaagt tagactgaaa aatctaattc ttgagtgcca ctacatgtcc catctctctt
     8101 tagttattaa aacagatgtc ccctacttat ctcgtggaga cagctgttcc actacatgtg
     8161 accatcagca tgccattgtc gctgcctaat acttcatagt ccatttttac gccaatgatc
     8221 gcatcagctc ctaatgcttt tgcacgttcg gccatttcgg caagtgcttc ttctcttgca
     8281 cccattagtt cgttttcata gctttttgag cggccgccaa agatatttcg caaccccgcc
     8341 tccaagtctt taaatgcatg gatcccagta atgacctcac caaaaacgat ccctttataa
     8401 gctactacgg cttttccctc tacactgttc gttgttgttg taatcattcg atcactcctc
     8461 tcttttaatt aaagtataac aaacttcaag aagcactaca catattttcc caaaattaga
     8521 aatttattat atacttgaat tgttcattaa tgaaagcgaa accaatcgtt agcaactatg
     8581 taaaagaaag gaagattctt gtgaaaaaaa gtattttgct tatttctcat agtcaaaaag
     8641 taacagatgg tattaaagaa atgattgagc agatgcaaaa atccgaagag gtgcaaattt
     8701 tttctctcgg cggaataaat ggcgagatcg gatcagaccc gatgaaaatc gtagaagcag
     8761 tcaatgaatc aagcgatgca gctagttatt ttgtttttgc ggatatcggt agcgcggtat
     8821 tgaactcgga actggcaaaa gacatgttgg aagaagagca gcagcaacgt tatcatctgg
     8881 tggatgcgcc tttagtggaa ggagcttttg cagcagccat cactgccggt ataacagatg
     8941 atactcagca aatcttaaca gaagcacaaa atgccggaaa gaaaggatgg gaataaattg
     9001 aaaaaaatca tgaatgatcc aagcaatatt gtcgaagaaa tgctggaagg attagtaaaa
     9061 agctatccag aacttgttca tcgtgtagaa tcttcccgtg ttgtagccaa gaatcagaaa
     9121 gcggaacaag ttggtttggt ttctggtgga ggaagcggac atgaaccatc ccatgccggg
     9181 tttgtagggg aagggatgtt aagtgcagcg gtgcttggtg atgtgtttac ttctccaact
     9241 ccagatcaga ttcagacggc tattaaggaa gccgatagtg gaaaaggagt tttgctgatc
     9301 gttaagaatt atacagggga tgcattgaac ttcgatatgg caaaggaatt agctgctatg
     9361 gacgatattg aagtagaaag tgtgatcgta gatgatgata tcgccgttga aaatagtacg
     9421 tatactgctg gaaaacgcgg agttgcaggt actgtccttg tacacaaaat cgtgggcgat
     9481 gcagcaagaa acggtgcttc cctagctgag ttgaaagaac tgggagaaaa ggtcgtacag
     9541 gcaactaaga cgatcggtct agcgcttcga gcagcaactg taccagaagt agggaaacca
     9601 ggattcgaac taggagaaga tgagatcgag tatggtgttg gtatccacgg tgagccaggc
     9661 tatcgtcgag aaaagatgca gccttctaaa gtactggcaa aggaacttgt tactaagatt
     9721 ttagatgatt actcgaattt accaaaagaa gcaggtgtac tagtcaacgg aatgggcggg
     9781 acgcctttga tggaacagtt cgtgttcatg aatgatgttt tagctctgtt ggaagaaaga
     9841 ggcgtcaatg tagttttccg aaaagtcggt aattttatga cctcactaga tatgcaaggt
     9901 ctttctctaa cactgatcga cttgacggag acacaatgga aagattcttt agaaagcaat
     9961 gtacagacga tttcatggta aaaaatctca agataaaagg gtgataatat gaaactaacc
    10021 gttcaagaaa tccaagaatg gctcacgcaa tttgcagagg caatcaatca gaacaaacaa
    10081 tatctcagtg atctagatac cccgattggc gatggagacc atggaaataa catgggaaga
    10141 ggggtttcag cttatgaaga agcttttcaa gccgatcatc ctgaaacaat cagcgataca
    10201 ttcaaagtat tctctatggc gatgatatcg aaagtcggtg gggcttctgg tccgttatac
    10261 ggatctgcat tcatgaacat gatgaaagcg acaaaagagg tcgattctat tgattctcaa
    10321 gaaaaattag gcgaagtgat cgagcaggga acagcgggta ttcaaagccg aggaaaggca
    10381 gaagctgacg ataaaacgat gttagatgtt tggctgccag tcacagaggc attgaaggca
    10441 gggaatttaa caaaagaaat cattgaccag gcaaaagaac acaccaaagt cttggtagct
    10501 aaaaaaggac gagcttccta tctaggagag cgtgcaatcg gacatatcga cccaggagct
    10561 gcttctagtg ccattttatt ttcaacgctt ttagatgtga tcaatcaacc ttaagttcaa
    10621 taaaactgcg gtgatgctca tcgcagtttt ttgtttggct gttcttatga cttgatgcag
    10681 aacagctttt tcacaacctc tatttgtcca tatcgcaaaa ttcaggtaga atacaaaaga
    10741 taacggaaag aggcgaaaca atggaacttg gaaaatcaga ttatcagttg tttgatcgac
    10801 caatctacgc attcaaacag ctcaaagaga gccatccaac agataagatt gaacaaatca
    10861 agaaagaata taaagaacac tggcaaaaat ggaaagagat tcagctccag acagctgcac
    10921 ttttgcctga tatgtacggc atgagcaaac ctaaaatcga aagctggacg aatggctgga
    10981 atttacgcag tcatttttgg agcgcgtacc gaagcgaatc tcgtcaagac gagaatgcct
    11041 gtctagcagt tttgttgaat caaaaacaat accaaatcta tttgatgtac caacattata
    11101 aaagcgaaga acgatatggt agcattgcag cgtataacca gttgcttgcg atactgaaag
    11161 agtggagcaa aacagtcgat atcaaggatt attacatatg gccgcaacca gaacatgaac
    11221 ttgacgacca cttagctttg tctgactatt tgtccgatac aaagaaacaa gaagagttga
    11281 aaaaagcgat gagagaccga acctttcaaa tgggtaaact attcttctat ccgcaagaaa
    11341 tcgaacacgt tgagcaaata accgctgaaa ccttacaaga actagcacca ctatatcaaa
    11401 agctaggtgc ggaaaaattt caatagacaa cacgaaataa gcaatgcgaa aaacaaacct
    11461 tactctcggc ttgcgagtga aggttt
//
LOCUS       DADGHT010000093        11425 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.094, whole genome shotgun sequence.
ACCESSION   DADGHT010000093 DADGHT010000000
VERSION     DADGHT010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.094"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(59..283)
                     /locus_tag="JX887_002289"
     CDS             complement(59..283)
                     /locus_tag="JX887_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAX1258232.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(481..2061)
                     /locus_tag="JX887_002290"
     CDS             complement(481..2061)
                     /locus_tag="JX887_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAX1258233.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2462..3838)
                     /locus_tag="JX887_002291"
     CDS             complement(2462..3838)
                     /locus_tag="JX887_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAX1258234.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3966..5084)
                     /locus_tag="JX887_002292"
     CDS             complement(3966..5084)
                     /locus_tag="JX887_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAX1258235.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5226..5660
                     /locus_tag="JX887_002293"
     CDS             5226..5660
                     /locus_tag="JX887_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1258236.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5738..6271)
                     /locus_tag="JX887_002294"
     CDS             complement(5738..6271)
                     /locus_tag="JX887_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAX1258237.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6365..7543)
                     /gene="mutY"
                     /locus_tag="JX887_002295"
     CDS             complement(6365..7543)
                     /gene="mutY"
                     /locus_tag="JX887_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAX1258238.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7536..8333)
                     /gene="recX"
                     /locus_tag="JX887_002296"
     CDS             complement(7536..8333)
                     /gene="recX"
                     /locus_tag="JX887_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAX1258239.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8440..9822
                     /gene="rlmD"
                     /locus_tag="JX887_002297"
     CDS             8440..9822
                     /gene="rlmD"
                     /locus_tag="JX887_002297"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAX1258240.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(9996..10574)
                     /locus_tag="JX887_002298"
     CDS             complement(9996..10574)
                     /locus_tag="JX887_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAX1258241.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10896..11366
                     /locus_tag="JX887_002299"
     CDS             10896..11366
                     /locus_tag="JX887_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAX1258242.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
BASE COUNT         3361 a         2293 c         1949 g         3822 t
ORIGIN      
        1 tgtgaattcc agcttatttc ttggagttaa acgcttctgt ctcagcctct ttttctttct
       61 agctttttga tttttctctt ttcttttgta cttttctctt ttcattttca gttctacgcg
      121 tgtctttatt tttaactttt tcctctttat ggatgattga tcgtactttt tgtgcaattt
      181 gctcgttttt gtcccagtct tttacatcta ataatcgaca taatcgtaac atctcttctt
      241 ttttctgttt ttttctttca cgtctttgcc attctgtttc catgtgtcac actctccttt
      301 ctttaatcat atgtacgcaa aataattttt atattttttt gattagacat ttctatgatt
      361 ttaatatagt aaaaagagcc gtcacggaaa atccgtcacg gctctaaaca aaatatgaga
      421 ggctgttttt gtttggctat tcttattact tgatgcaggg cagcttgtgt caagacttct
      481 ttacatcaaa ctttttaatt ttacattggg atatttatcc gcaaaccagc gttctgcaaa
      541 ttggttctcg aataagaaca acggttggtc gaaacggtca cgagccaaga tattgcgact
      601 tgaactcatc ttctcatcca aatcttctgg atcgatccag cgagcgattt tgtgtcccat
      661 tggagacatg attacttcgg cgttatactc atttaacata cgatattgga atacttcgaa
      721 ttgtagctga ccaacagctc caatgatata ttcttccgtt agatatgttt tataaagctg
      781 aatcgctcct tcttgaacta attgatagat tcctttgtgg aaggattttt gtttcatgac
      841 attttttgca gtcactttca taaacagctc tggagtaaat gaagggagtt cttcataagc
      901 aacttttagt tttccttcga acaatgtatc cccaatctga taattgcctg tatcatatac
      961 accgatgata tcgcctgcta ctgctttttc gacgttttct ctcgaatctg ccataaattg
     1021 tgtgacattg cttaatttca gttttttatt tgtacgttcc aaccagacat ccattcctcg
     1081 ttcgaatgtt ccagaacaga ttcggacaaa agcgattcgg tcacgatggg ctggattcat
     1141 atttgcttgg atcttgaata cgaaacctga aaattcttcc tcataaggac ttaccatctg
     1201 atcatcttgt gttttgtgtc cataaggagc tggtgccaat tcaacgaaag tctctaaaaa
     1261 agtctgtaca ccgaagttag tcaatgcaga accaaaaaat actggtgtct gatcgccacg
     1321 agcaattttt tcttgattaa atgcatctcc agcctctttg attagttcta cttcttctaa
     1381 gacttgttca tataaggaat tttcagttag aggatgattt tcgggaagca gtccatcttc
     1441 atccaattct actaatcgtt catcctgata attttccgga cgataaaact ctacacgatt
     1501 atggtagata tcataaagac cttctagccc tttacccata ccgattggcc aattcatcgg
     1561 ataagattcg atatctaata gctcttctaa ttcttctaac aattccaatg gttcacgacc
     1621 atcacgatct agtttgttga taaaagtaaa tatcgggatg ccacgttttt ttacaacttg
     1681 gaataatttc tttgtctgtg cttcgatccc ttttgcacta tcgattacca tgaccgcact
     1741 atccacggcc atcaaagtac gataagtatc ttcagaaaaa tcttcatgtc ctggtgtatc
     1801 caagatattt actcgtttcc cttgataatc aaactgcata acagaactag taacagaaat
     1861 cccacgttgt ttctcgattt ccatccagtc tgatttggca aaattacctg tttttttgcc
     1921 ttttacggtc ccggcttgac ggatagcccc accaaacaat agtaattgtt ctgtaatcgt
     1981 tgttttccca gcatccggat gggaaatgat cgcaaaagtt ctgcgattgt ccacttgttg
     2041 ctttaatttt ggattattca taacctaact ccatttcttc cattcaatta tttatatttt
     2101 ctctaggcac agattgtccg atctcttaaa gaaagacaat ttcatatagg gctgtgacaa
     2161 aagccgtgta gcagtctctt tttccgagta aacggcgttc tagagacagc ctatcagcaa
     2221 taagcccacc caagccaaaa atacgaaaag ctgtttttgc ttggctgctc ttattactta
     2281 atgcaggata gctttttcac aacctttgtc aactactaca actgaatcag tatagcatgg
     2341 attcagcgaa tgaaaaagcc accaaaccat aagagtcaaa tatttttttg tcagctgact
     2401 aaaagaaaag acgtgttgct tgtttattca agcaacacgt ctttcataac caagtttcca
     2461 attatcttct tggctcgtca tcttcgaatt cttttctgaa gtatcttcgt tcttcttcag
     2521 gttccgcttc tgtttcttcc ggatcatgaa aaatgacacg gattttaagg attcgagaac
     2581 cttccatttc ttcagaaacc agcgtaatat tatcgacatc aaacgataac ttttcgcctt
     2641 catccggaat catgcctaat gctgtaatca aataaccagc catcgtatct acatcactca
     2701 tatgcagatc actgtcaaaa gcttcattga actcatcaat cagcatacgt ccttggatga
     2761 tatattcgtg ttcatcgatt ttttcataaa gattctcaac ttcatctgat tcatcatcga
     2821 tttctccgac gatttcttct aaaaggtctt ctagtgttgc taacccaacg acgccgccat
     2881 attcatctaa taaaatagcc atctgattct gcgtcttttt catttcatat aacagatcat
     2941 caataaagac cgtttcagga acgaataaag gctcctgcat gattttcttg atatctaaat
     3001 tatcaaagcc gaatttatgg gcagctttta gtaaattctt tgtatgaagg attccgacta
     3061 ctttatcttt gtcttcgtta taaacaggga ttcttgaata gttttcggat aaaacttcat
     3121 tcacattttc ttccacagtg tcgttgatat caatcataaa tgcatccgtt cgtgggacca
     3181 tgacttctcg ggcaactttc gtatcaagag aaaaaacccc ttggagcatt tctaattctt
     3241 cattattcaa tacgccttcg ttttcaagca tataacgcat ttcatctctg gtcatttttg
     3301 aatcttcatc atcaaaagtc atcggcgtga tacgcgccaa taaacttgtg gaagcagaaa
     3361 gcagccagac gaagggctta gctactacac caatcaagcg tatcagccct gaagtgaact
     3421 ttgcgacttc ttctgattta tttaaagcaa tacgtttagg gtacaattct ccaaaaacaa
     3481 tcgatacata ggtcaaaata gccagcacaa tgatatttgc aatatttttt gccgctgtgc
     3541 cgccacctaa taccggagct aaccgttccg ataaagtatt agctagtgaa gcaccagaca
     3601 aaatgttgac caaagtgatt cctacttgga ttgtcgatag gaaattattt ggattctgca
     3661 atatttttaa aagcttttga gatttcacat ctccttcatc agctttttgc tcgattcgat
     3721 tcttattgat cgaaacaaca gcaatttcgg aagctgctaa aaaagcattg atcaatgtca
     3781 aaacgatcaa taataaaatc tgcgctaaca gcgactgact ctcagggtca gcattcataa
     3841 tcgcattctc tccttataaa attaattttt agtttacgat agaaaaaaac gtggcactat
     3901 agccacgtta aaatggtatc acaaagcaat tttctttgca ataaaaacaa gtgtactaaa
     3961 actacctacg aggtcgtagc aattttcttc ttgttttcat tttgcttgtc ttctttgacg
     4021 attttgatta tataggaaat gatcgtcttg cagattgcgt aaaaaggaac acctaagaag
     4081 ataccaagca atccggcaat atttccagct actagaagaa cgataatgat cgttaatgga
     4141 tggattttca gtgatttccc aattacatta ggataaatga tattcccatc caactgttgg
     4201 acgattagca caaccacaca acaaagtaat gcttttaccg gatcattgaa gactgttact
     4261 agaaatgcag gtgctagtcc tagataaggt cctaaatatg gaattaggtt tgtcaatccc
     4321 gcaatgaccc caaataagaa agcataatcc acaccaatta ccatatatcc taaaaatgtg
     4381 aaggtaccaa cgaataaaca ttcgattgct tgtccgctaa tgtaattagc caatgtttta
     4441 ttcagttgcc ccaataactc cacaatttgg tttcttcttt tttctgggaa aaactgttgg
     4501 atgtttggca ctagtttttc tccgtctttc aacatataga acaagatgaa tggtgctgta
     4561 atgattacta cggttgccga agcgatcgtt ccaacgatcg aacctaaact attggatact
     4621 ccactaagga attgctgaat gattgtcccg taagaaatgt ctaattgctc aaaatattta
     4681 ttgatatcta cttccttgaa caaaggcaat tcggctacct cttttaacca gctttctacc
     4741 tgtttgatga aatcaggcat attagatgcc aatgaggaaa tttgctgtac tagacttggg
     4801 atgacactaa gtaaaatcca aataattgct gcaactaaaa ggagcagcac aattgcgaca
     4861 gcccatattc ttttgatttt tgctttcatc aacagcttga caataggatt caataaatag
     4921 taaagaaagc ctgcaatcag tacaggtgca aataacgtgg aaaaaaatgt cccgatcggt
     4981 tcgaaaataa agtttatttc tgatgaaatc atgatcaatg cagctatgat caataattca
     5041 agcgaccaaa acattagttt agactgtcta agtttttcaa acaatagatt tcctcctttc
     5101 tttcttacta gtatatatta tattcgttaa aaattctttt attctttttt tatttttgaa
     5161 aacttgccat actttttatt tgttttattt tccagtatac tatacgaaag gaaggtggct
     5221 agaccatgaa agttgtacaa acaaaagata caatgagcaa tatttactta gatgctgtac
     5281 ggatcaggca tcaagttttt gtagtcgaac agggtgtgcc tttgtctcga gaaatagaca
     5341 aagatgaagc ccattgtatc cacttcgtcc tgtactcaga taaaaaagaa ccgcaaggaa
     5401 ctgtacgtct tttgccttta gaaaacggaa aaatgaaatt acagcggatg gcgattcttt
     5461 ctgaatacag acaccaaggg ttaggaaaaa tattgattga agaagcagaa aactttgcta
     5521 agaatcaagg ctataatacg attttattag gggcacagtc cacagctgaa actttttacg
     5581 aaaaactagg atatacagct tacggcgatc cttttgaaga tgctggcatg cctcatattt
     5641 atatgaaaaa gactttataa aaatttattt cgaaaaaagc aaaaaacagc aagcttttga
     5701 gaaaaatctc tcactggctt actgttcttt tttgtgttta cttacgcgac aattgcttgt
     5761 aacggttata ccaaatatca atatagcctt ccgagaacgg gccatctcca ttattgatcc
     5821 agtcaaccag aatcttcaca ttttctttta ggatgaagtc aatatcgttc gggtaattca
     5881 tcattttgct gtgcatctca tattcatcga catccaatag tcgtttctcg ccgtcaggaa
     5941 ataccttgat atccaagtca tagtcgatat atttcaaggc ctcatcgtcc agcaaaaaag
     6001 gtgaagctag attacaataa taggaaaccc ccttttctct gatcattgct attacattga
     6061 accagtattt tttatgaaaa taaacaatcg ctggttcgcg cgttacccat cggcgtccat
     6121 cagattcagt gactaatgtg tgatcattca cgccgatcat agagtgttcg cttgttttta
     6181 ataccatggt atctcgccac gttcgatgca atttgccgtc gtgcttgtaa ctttggatcg
     6241 tcacaaactc tccttctttt ggaactccca tagcaaccct tccttaagca gcattttgtg
     6301 ctttgtgttt gggtgttcat tacaccgaca tcataattat tatatcaata aaaatgagct
     6361 ttgcctagaa aggattccta ttgtttcgat ttttctctaa ctgatctacc agtttcattt
     6421 ggaccttagg aaaaacgacc gaatcaaatg catcaggctt caaccacttc gaagttttgt
     6481 tctcggtaaa ttcttgttct gctccctcgg ttgcccgtcc gtaaaaaagg agaacatgcc
     6541 atttcagatg actaaaaata tgagtaactt ctcctaaatg tcgtgtctgc caaacaaaga
     6601 gttcctgctt ttcaaatggg agattttgct cttcttctgc tactaggtca tcaaacagat
     6661 cgatttctgg ctttgtttcc cattcttttt tcaatcgctc atactcctct tgtgtcactt
     6721 ccatcattgg aaatgtccac atattcgcca gcaatttttg gctatctctt tcttcaaaat
     6781 aatacgctcc agaatgattt tgaagagctg cactgatata ataaacgtct tttggctttg
     6841 ctttttttgt ttttacagga aaactcgttt ggattcctcg tttgttagct aaacaaaagg
     6901 cttggatcgg acaagtctca cactttggag aagttggtgt acagatagct gaacctagat
     6961 ccatcattgc ttggttgaat tcacctggat gcttttcatc aatgattttc cgcatcgctt
     7021 catcaaagat tttcctgcta gaagcttttg cgatgtctgc ttcaatgcaa aacaatctgc
     7081 tgactactcg catcacgttg ccgtcaactg caggttctgg aagtccaaat gcgatacttg
     7141 caatcgcgcc tgtcgtatat ggtcctattc ccttcaatga gctaatttct tcaggcgttt
     7201 gcggcatttc cccatcaaat tctgacatga tctgtttagc agcagcttgg atgttccggg
     7261 ctcttgagta ataaccaagg ccctcccatg cttttaaaag cttttcttct ggagcatttg
     7321 ctagctcttc aattgtagga aaccattcca tgaaacgata aaaataatcg atcactgtgt
     7381 ctactctggt ttgctgaagc atgatctcag agatccagat acgataagga tcacgattat
     7441 agcgccaagg caggtttctt ttttcttgtt cataccattg aatgaactga tcttgaaatt
     7501 cttttgtttc tttatctgtc catttttccc attctttatt cactttcctc ttccttttcc
     7561 gtaatgaatc gctggatcat atccaaatca aatccttttt gatataagct ttgctttact
     7621 tttagatttc tttttttagg ttcaaacctt aaatttcttc gccatagttt atctccttgt
     7681 ttgactaaat aatcatattc tatttcttga tctgcttctt gcggaagatc agctatcgct
     7741 tgttggatca cttcttgaga aaagcctttc gtcatcaatg tttgttggat ttttctcaat
     7801 aattcttttt ggctttttcc gtgatttttt ccaaacgctt tttcggctgt ctgatgtgca
     7861 ttttgaactt ggtcttcaaa tgtatattgg ctgagcgctt gttcaatgat ttcaggtttc
     7921 aaaccttttt gctgcatctg ctgcgctaat ttctttggtc ctttgtcact taagcgcata
     7981 ttcgtgcgca cataactttc cccatagacc aaatcatcga caaggtccaa ttcttttaag
     8041 cgggctacga ttttatttcg atcttcttga aggatttcct tttcttttaa gtatgttcgg
     8101 atttcttttt ccgatcgcaa ctgataactt aagtaattca ttgctaggtg aaaaccgaaa
     8161 tcagctccgc tactcttctt gatctcttgg atagtttctt cgtctaattc ccgtcctttt
     8221 aataatcgat agcgtactaa tacatcttca gatacttgta aagcttctcc ttcagataaa
     8281 tctacgcgat agaaagggcc tttgccttta ctgattctcg taacggttaa cataaacatc
     8341 ctcctcgaac atatattctc tatcatacca cagaaaatcc ccgtaatcag gtattatatg
     8401 ttagaataaa ccacagaaaa aagaaaaagg gagatactta tggcagaaac aattgtcaaa
     8461 actggacaaa cggttccttt gaaaatcaag cgtttaggca taaatggtga aggaatcggt
     8521 tatttcaaac ggttgatcat atttgttcca tatgcactac caaaagaaga agtactagtg
     8581 aaaatcacga aagcaactcc tcgctatgca gaaggagaat taataaaagt caaaaaaaca
     8641 agcaaagatc gcgtagtggc accatgtcct gtttactatg aatgcggtgg ctgtcaatta
     8701 caacacttag cttatcaagc tcaattggat tttaaaaagg atctgctttt gcaagcattg
     8761 gaaaaattca aaccagcagg ctttcgatct tatcaacttt tgccgacgat cgggatggat
     8821 gagccttggc attatagaaa caaagcacaa tttcagttac gaaaaaataa gcagactcaa
     8881 aaaattgaag ctggtttata cgaagcaaac tctcatcagt tagtccctat aacagactgc
     8941 ttggttcaag aacctcgaac acaaaaagta atgaatactg ttgttcaact attgaataaa
     9001 tttgatgcac ccatctatga tgaacggaca aacagtggaa tcttccgcac aatcatggtt
     9061 agaatcggtg ttaaaactgg ggagttacaa gttgttttta ttactcgcag taaaaaattc
     9121 ccgcaaaaaa acgcaatgat ccgtgagatc aatgaacgac tgcccgaagt tgtttcaatc
     9181 atgcaaaatg tccaggcaca aaaaacgtct ctcgtgatgg gggatgaaac gatccactta
     9241 tggggaaaag aagccattga agaacaaatc aatgaagtga ctttcgatct ttctcctcgt
     9301 gccttctttc aactcaatcc tcagcagacc gaattgcttt atggcgaagg aatcaaagca
     9361 ttagatgtcc agcctaatga aacgatcgtg gatgcttatt gcggagttgg gacgatcggc
     9421 ttaagtgtag caaaacaagc caaagaagta cggggaatgg ataccgttcc tcaagcaatc
     9481 gctgatgcaa aaaaaaatgc ggaaagatta ggatatcaca acactcgata tgaagtcggg
     9541 acagcagagc aagttctgcc taaatggttg aatgaaggtt ttcagcctga tggtatcatc
     9601 gtagatccac cacgtacggg tttggataac gcattgatcc aatcattatt gaaataccct
     9661 ccaaaaaaac ttgtttatat ctcctgtaat gtttctacac ttgccagaga tctggttaat
     9721 ttaagtaaaa agttcaagat tgaatattta cagtccgtcg acatgtttcc tcagactgca
     9781 cgttgtgaag ttgtcgtgaa gatgacgaga ctcgctgact aaatgaaaga ggttgtgaaa
     9841 aagtctgccc tgtatcaagt aataagaaca gccaaacaaa aatagctctt catgttttat
     9901 gaatactgta cttgtgaccg aagagttaac aggaggacac tatttattta aaaaaagggt
     9961 tgtgacatag tttttgtcac agcccttttt gattattatt ggatattcac gtctatcact
    10021 tgataaaatg catttgtcgt atcgctgata ttccatactg ctaaaatcac attatatcct
    10081 tttcgatcct gcggaagtgt gatcgtttgg ttgactgttt ttggtggaac agttgctttg
    10141 tcgtctattt ttgtgatcaa ttcaaaatca ctaaatttca aaggttgatt aggattccaa
    10201 gttggtttgg taatgtagta atcccaagta cttgtccgat gttgtgctgt taaattccaa
    10261 gtaatattta atgttcctgg attaaccatg tttttatgcc atctgttaga tgtctgttca
    10321 tctaaaggct caaagccgct gactcctgca ctagcaattt ttccatcaat gaatgtattt
    10381 ttggtagctt cgatactttg cggttcccat tgtgctcttc cgacattttg atttaagttt
    10441 cctgctgctg atgttcctag gtatgcacgg cttcctggag aagtaatata accatgcgca
    10501 aaacctggaa tgctaaaacc gaacaaccct aaactaacta acccaataaa caataacgta
    10561 ctaatctttt tcatgtagaa acctccttca tttgataacc acattgtaaa cgctttattg
    10621 tattaacaca aacattatgc ttttataatt ttatgttgaa gtaaaaaagg tgaaaaaagt
    10681 aagatgcaga ttataacaga agtagacgag aaaagtacaa atagaaaaca tgagaatcaa
    10741 atcatatgat ctttttcaaa aacatcattc atataaacaa atgttcaact ttttaataac
    10801 aacaattatc aatttttttc ttacttcaca aactaaatac aggtcttgct gtgagccttc
    10861 atggtaaact aatattatag aaaggagtta gtaaaatgaa gatgataaaa gatattcgtt
    10921 tttgggtttg tgttatagga attgtcatat taggcttttt atcagggttg cttagcggaa
    10981 atcccggaaa atattactat tctttgcaac ttccaccatt tgcaccacct agctggatat
    11041 ttgggccgat gtggacctta ctgtatatat tgatgggtat ttctctttat ttgttactta
    11101 atcacaacaa caaaaaacag cgaaacaatc ttgtcggtct ttttgtgatt cagttcattt
    11161 ttaattttat atggtctgct ctatttttta atttaagaaa tattttcatt gcagcaatcg
    11221 atattacact tttagttatt ttcttgtcag tgcttatgta tcagttgtgg ctgcatcatc
    11281 gcctggcaat gtggctcatg attccttatt atttatgggt actattcgca actctattga
    11341 attattcaat ttatttttta aactaagcgc taaaaagaga cgtcctgtaa tttaacacat
    11401 agaaaaagtg ccacctaagt tagat
//
LOCUS       DADGHT010000094        11411 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.095, whole genome shotgun sequence.
ACCESSION   DADGHT010000094 DADGHT010000000
VERSION     DADGHT010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.095"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(71..1492)
                     /locus_tag="JX887_002300"
     CDS             complement(71..1492)
                     /locus_tag="JX887_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1258243.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1735..3612)
                     /gene="tdc"
                     /locus_tag="JX887_002301"
     CDS             complement(1735..3612)
                     /gene="tdc"
                     /locus_tag="JX887_002301"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAX1258244.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3903..5159)
                     /locus_tag="JX887_002302"
     CDS             complement(3903..5159)
                     /locus_tag="JX887_002302"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAX1258245.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            5739..7040
                     /locus_tag="JX887_002303"
     CDS             5739..7040
                     /locus_tag="JX887_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAX1258246.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7109..7708)
                     /locus_tag="JX887_002304"
     CDS             complement(7109..7708)
                     /locus_tag="JX887_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1258247.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            7963..8844
                     /locus_tag="JX887_002305"
     CDS             7963..8844
                     /locus_tag="JX887_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1258248.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8857..10467
                     /locus_tag="JX887_002306"
     CDS             8857..10467
                     /locus_tag="JX887_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAX1258249.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10544..11203)
                     /locus_tag="JX887_002307"
     CDS             complement(10544..11203)
                     /locus_tag="JX887_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAX1258250.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
BASE COUNT         3326 a         2281 c         2075 g         3729 t
ORIGIN      
        1 aaaaaactat tcacttggca ggacctccta ctaaatcagc gacaaaacgt cggctgaaag
       61 acttattttt ttatttttct tctaaacttt tttctacctc aatcccccaa gaatctttct
      121 tgaagtgatt gatgatcaat ggaataacga acatgaccac tgtgatagct gctactaata
      181 atgcatcact caatgtcgct gtacctaatg tagcaaatac gacaacgatg atagagaaga
      241 tcagcatgca gctgactacc caagctaatc cgtttccgtt tttaccaatt cggtaaggac
      301 gttcgaattc tggatgtttc ttacgcattt taagcaatga aacagcaatc aaaatgtaca
      361 cgatacaata aataacagtt gtagcatttg taagtgtcaa gaatacagca cttacgtcat
      421 ccattacacc ataaagcaaa gcaaataatg aaataacgat tgattgtgtt agaacgacat
      481 ttctagatac gccgtatttg ttttctttat ggaatccgaa ttttggtgga aggaatcctt
      541 cacgagctac ttggatgatt gtttttgatg gtccagtaac ccaagctgat aattgtaaaa
      601 gcacaccaat aaataccatg aagctgaaga tatttccgat cacttctggt aagcctagga
      661 tttgacagtc aatcaagata ggctgcgtga tatttgctaa ttccattttt ccatctggta
      721 cgacatttgc tacaagcatc gcattgatga cattcaataa aactaatccg atcaaagcga
      781 taaatacgcc ttttgtataa ttttttgttg cgtctttcaa acgaggcatg taaacagaac
      841 tcatttcgat cccaacaaaa ataaatgtga taccagctaa gtatttcaat gaatcaatat
      901 gttccaagtc agggaaagct tttgaccatg aaaagtcacc tagatagccg tttgagacta
      961 gtccgacttt gaaggctgcc aaaacaccta aaacgaacat gatgactact gggatatata
     1021 cccctagcca tacaccgatg ttcccgccga cttttgccat atcgaatttc aagttcaaga
     1081 tcgtgatgat ccagtagata actaaaatac aacctaaaac gaaccagtga ttattgccaa
     1141 gttctacatt accaaatgtg tttcctaaca atggtcctaa agtagaagcg accattacca
     1201 tacctgggaa catttgcacc cataatagcc atgcaacgac aaatccccat ttgctgccca
     1261 gtgctgtttt tacccataac tgaggaccgc cttcttgagg aagcatcgtg gaaagctcac
     1321 cggaaaccat tgatatcgga ccggcaaaaa acaaaactgc aaaaattgaa taaaaaatca
     1381 atgtccaacc gactgcggct aacgtaggaa tactccgaac cgttgcacac agtgccattg
     1441 tcagaccgat aaaggtccca agacccattt tacttacttc agatttactc accgttgaca
     1501 ctctccttga ttttttggat aaaataacgg tgtctttgaa gtagtttcag caataaacga
     1561 aacaattcag cgaatatttg aggggattct ttgagtttat tgcttgaagg gtttcttcaa
     1621 agacaacctc aaaacaaagg gatcgaagag cttaggtctc cccttgctct tcagatccaa
     1681 acatgcgtca gaaacagtta gtattcaagc tgttttctaa catgattacc ttgcttattt
     1741 tgcttcgctt gccaataatt ggtctgcgta gattttttcc aatttttctt gaagagctgc
     1801 tttgattttt tcagcatatt cttcaaagtg ttcttctttg ttcatgtatg gtgtcattac
     1861 gctggcacgc aatacagtta cttttccggc acggttccat tcttcatctg agaatcctag
     1921 ttggttcaca aattgtaatg ggctgttgcc atagtctggg atagcaaagt cagtatgtga
     1981 agttaagaac tcattaccgt aaatgcttcc tttcacgtat gaagaataat catatacgtc
     2041 atggttcaat ttattcattg caactaagtc atcgttgcct ttttctttga atacatagtc
     2101 taccatattg aaatctggat aagttaatgg atgaacttcg atttctttgt ctcctacttt
     2161 aaatgacaag tcattcaaga agttgtagaa acgatgtgca ccttcgattg atgcacccat
     2221 taatttacca tatcctgtga cattcaaagg taagacatgg tgtgctgccc aaacgctggc
     2281 tgctgttgcc cctgcttttg aaccttccaa gatataagcc ccaagtaatg ctgggatatc
     2341 tgcgcctttt tcaaatacat atgtcgcaaa gtaagagata acgtctctca tgcggatatc
     2401 tttgatgacg ataccaccgg cagaatatgg aacatagccc attttatgtg ggtcaatcgt
     2461 tacagattct gcttcttcga ttgctttata tgcactgtgt acttcttcta agatataatc
     2521 tttgttttct gtaaagacat tgtatttgta atgaacatct tttaaatctt caaatggaat
     2581 gaagttgttg tcttcgtcta agaaaatcgc acggccgtat ccgccataag cagcatctac
     2641 gtgtaagtag aagtaaatac cgtctttttc taatacgcga cgcaatgcaa cgattttatc
     2701 gataccgtcg attgctcctt cttctgttga tcctacaaca ccgactacac ctaggattgg
     2761 tgttttttca gctgctagac cacgaacgat tttttcaagt tcgttgatgt ccatgcgata
     2821 gttgtggtca actggcactg gaatcacttg gtctaaaccg ataccgatga tgtcggcagc
     2881 ttttagccat gaatagtgtt tagtttgtgg aaccaaccat tttcctaatt tttctaaatg
     2941 ttttccgcta cgtgctgagt gagctttgat ttcgtcgatt ttttctggga cgctgtctaa
     3001 cagattcatg atttcttctg ttgacaagtt cattaattcc caatcgcttt ttccagcaac
     3061 tagttcaggt gtcacttctt tcattgcaag cggcaatgat ttgatgttgc gggcatacca
     3121 aagtccttct aagtttgcta aagaaccatc agcaacgatg tggccccagc catctttata
     3181 gctcattaat tttgcaaatt ccattcctac ttcttcttcc atttggcttg ttgcaggaga
     3241 agattcatag gcaacgttat taccattcca tagcatagca aaattgtacg ctagtaaaga
     3301 tggcatcaat gtttcagagt tcatatgacc ccagtaacgt ccggcattat gccaaggaac
     3361 ggaatgggta cgcatccgcg ctgaaatttc tgatagaaca tcctttgttt tattcacagt
     3421 gtgttcaaaa ctagcactgc ttttttcttc tggcgtaata ataggcatgt cttgaggcat
     3481 gtagttttga cgccagccta aatgttcatc caccaattca ttcaacaaag ctttatagat
     3541 ttggccgttc tcagctttgt ccccaatgaa tagggcattt aggtttagat ctttcgacaa
     3601 tgattcactc atagtgaaac cctcctaaaa aaatatttaa attttgtcga gccctacatt
     3661 acacctgttc ttctattctg taaactaagt tttggcctga tttttaatca tattttaata
     3721 tgtatcaatt atccgaattg ttcacacttt tgaaataatt aaaaaaaacg agggaattta
     3781 caaatgtaaa ctccctcgca aagattgtat taacgacaac cagcgttcta ttttaggatg
     3841 ggtttcaaaa ttggaatgtt gtaatagtat ttcccttttt caaggtaaaa acttactaaa
     3901 ttctaatcaa ttactttggc caaaaagtaa tttttcttac cttttcgaat aaccacaaac
     3961 ttaccatcga attcatcgga tggatttatg acaaaattta aatcggtaac gcggtcaccg
     4021 ttaatactta tagctccgtt tgaaacatct tcacgtgctt gacgtttaga tggttcaatt
     4081 tttgtggaaa caagcagttc cacgatattt tcaggtgtgc ttgaaatttc aacgttcggc
     4141 attttaccga atccttgcgc gatttcttcc gcatttagtt ctttaatatt tccagagaac
     4201 aatgcttgcg ttattttttg cgcttctttc aagtcttctt cactatgcac aaatcttgta
     4261 acttcttctg ccaaacggcg ttgtgcttca cgtttctcag gttctgtctc tacttttttc
     4321 gctaagtctt cgatttcttc ttgagacaag aaagtaaaga atttcaagta tttcactaca
     4381 tcgcgatcat cttgattcaa ccagaattgg tagaactcaa atggtgaagt tttcttcgga
     4441 tcaagccaaa cggcaccgcc tgcagttttt ccgaatttcg ttccgtcagc cttcagcatc
     4501 aatgggatcg ttaaaccgaa cgcttctgct tctggtcctt ctaattttcg gattaggtct
     4561 aatccagctg tgatatttcc ccattggtct gctccaccga tttgcaattg cacatcgtat
     4621 gttttatgca gatgcaaaaa gtcgatagat tgcaggattt ggtaagtaaa ctctgtaaat
     4681 gagattccta cttccaaacg gctggcaacg atatcttttg ctaacatcgt gttgatgttg
     4741 aagtttttac cgtagtctct caaaaattca agtaaagaga tttttgacaa ccagtcgtag
     4801 ttgttcacaa atgtgatatt tgcatcttta ccaaacaatt ttctcatttg attggaaagt
     4861 gcgtccacgt tatgttgcac ttgttccatc gtttgcaaca cacgttctgt tttgcggccg
     4921 cttgggtcgc cgatcgttcc tgttccgccg ccaatcagaa tatatggatg atggcctgcc
     4981 aattggaatc ttttcatcat cataaatgga atcaaatgtc cgatatgcat cgaatcacca
     5041 gttggatcaa cgccgcaata aagtgaaatg ctcttttctt caacgagctc gcgaagtctt
     5101 tcttcgtttg tttgctgatt aatggcgtcg cgccaagtta attcatcaat aatattcatt
     5161 ttactgacct ccgtgtagtt tttttatgaa agcaggaacc tgctagcatg tgtaattaat
     5221 tatttcttca ggataggata ggaaataaaa aaagtccctt ggcatataag ccaagggacg
     5281 aaatctcgcg gtaccaccca atttgtatgt ctagatatcc aacatacctc tcgaacattt
     5341 aacgctgtcg cgtggcaatc actgccaaag actcctgaaa tgtaattcgc tttaaagcat
     5401 gtactggttt gcagcgacca ccagctttct gaaacattgg ctttaacaac tacttcgttt
     5461 cgatcttcgt cttgttatta ttaatatgtg tctatcatag agcgcaactt tttctttgtc
     5521 aacagaaaaa ggatattttt tttaaattcc tcattttttc ttttttgaat ccgctctaat
     5581 tccgaacatt ttattttcaa ttattgttaa aagaaataac tttttctgta ttttttctgc
     5641 aatttatcga gaagtcactt tactttgcct cttattcttt cttcgttaca ataaggaatg
     5701 ggacaagtaa aaaaatgaaa aagcaaggga cgaggtatat ggaaaaaaag caaaaaatta
     5761 ttttaggagc cacttctgct ttaactatcg ttattttaat tctaagtttg ttttttgtca
     5821 tccgatcatc tacaaaaaaa gaaccaatca ttcctgaaaa aaaaataaca gaaaaagcaa
     5881 aagaaccgac agatgataag caacaactag ttactcaagc aaaaaatctg gctcaaagct
     5941 acgattatga ccaagcgatt gcgttattgg aaaaagatag taagaacgga tctactgaaa
     6001 cacaacagct tcttcaaaca ctaaaaaagg agaaagaaca actgatcgac tggtctgatc
     6061 ctactcagat ctctcatgtc tttttccaca gcttgatcgt ggacccgcaa aaagccttcc
     6121 actctcaaca ggcacaagga tacaaagatt atatggtgac tgttgaagaa ttcaaccgtt
     6181 cgatcgaaca actttatcaa aatgattttg ttttagttaa tttgaatgat ttgatccaaa
     6241 aagacgaaca aggaaatctt tcctttaacg ggcttgcgct acctgaagga aaaaaaccat
     6301 tggttctttc acaagatgat gtcagctatt atgaatatat ggataattcc ggttttccta
     6361 gccgattggt cgtatcaaat aacaatgaaa tcaaaaatgt ctataaagag aaagataaag
     6421 aagaaatcgg tgactttgac atggttcctc tgatcgatgc ctttgtcaag aaacatcctg
     6481 atttttctta tcgaggcgca aaaggtacct tggccctgac aggttacaac ggagttttag
     6541 gttatcgaac atcaaaatct caatatggag acaatgaaaa aacaaaaaaa gagattaaag
     6601 aagctaaaaa agtggcggaa cagttgaaga aagacggctg gagctttgct tcccatacat
     6661 ggggtcactt gaatatgact caagcttcac tagaagatgt aaaaaaagac aatgaattgt
     6721 ggcagcaaga agttgcacct atcctaggaa aaacaaatat tctgatttat ccatttggtg
     6781 cagacatcag cgactggcag ccttattcag cagaaaatca aaaatttgct tacttgaaga
     6841 gtcaaggttt cgatattttc tgtaatgtcg atgcttctac accagcttgg ggacaattag
     6901 gtacggattt ctatcgaaat gctcggatca atatcgatgg cattcgtttt caatctgatt
     6961 tagacggaaa aaatcctatt cttgatccat tcatcaatgt ccatgatgtc tatgacaaag
     7021 aagcacgcga atctgcttga ttttacgtca tttatgaacc aaaaaagccg aactgacatt
     7081 ttatcgtcag tttcggcttt tttatgcttt atttcttctt cggtgcgatt cccttgatca
     7141 ggacttctgt ccattctgct gtatatggaa gcagttttgc gtatatctcc ggcttagaaa
     7201 ttccttctac cattgcttga aaatagagga tcaagaactc atccgaatat ttcaaatcca
     7261 cttttccttc tttccgccct cgatggaaaa gatcaagcat gatactgaaa ctttcttgcg
     7321 tatacgcatc catcgcgtca gaaaattctt ttttttcttt ttttgtatag tatgtcatca
     7381 aatcgatata aaattgtttg ttcactcgat tgagataacg gattttgttt tcactcatgg
     7441 caatcagtgt ttcttcaaat ggaagatttt ccgcaatcaa cgctttcgct tcttgcccta
     7501 aatcattcat aaatgcaaaa aatacttcat aaatcagccc ttccttgctg ccaaaatatt
     7561 taaaaatcgt cgctttactt acctgagcgt tctcagctac cttatccatt gtcactccag
     7621 cggttcctat gtctgtgttc atcaagtcaa aagctgcttg taaaatctct ttctttttct
     7681 cttgtgctct cttttcaaaa ccgttcattt gtagagcctc ccgtaatttt aaacttttat
     7741 aatatatata gttcaaattt attctgaggt ttattataac tatctattga gaaagtatca
     7801 agctagcaat tccttgttta tgaattcatt gacagaaatt tataaaaaga atattatgta
     7861 ctaaaataat aaaaaaaagt tttataaaaa ggtataaaac ctttttatta aactatttaa
     7921 tcttgtttag tatatatttt tagaaaaagg agtggggttt ttatggcaga aatcgtcaaa
     7981 gtcacacatt tgaaaaagag ctttggtcgt ttcgaagctt taaaagatgt ctctttcacc
     8041 gtacattcag gtgaagtcgt tggatttatc ggaccaaatg gttctggaaa atccacgacg
     8101 attcggacac ttttagggat tataaaaaaa gacggcggaa cggcaacgat ttttgggcaa
     8161 gatgtatggg aagatagttt atctatccat gaacgtcttt cttatgttcc aggcgatatc
     8221 tctttgtggg gaaatttgac tggaggagcg atcatcgatc tcttcatgaa gcttcatgga
     8281 aaagggagtg ctcaaaaaaa agatgaactg attcaacgtt tctctcttga tcctaagaaa
     8341 aaagcaaaaa actattcaaa aggaaatcgc caaaaagtgg gcttgattgc tgctttggct
     8401 gttgattcgg atctctattt atttgatgag cctacttctg gtttagatcc tttgatggaa
     8461 acgattttcc aagaagaagt tgaaaaattg aaagaacagg gcaaatccat cctactttct
     8521 tctcatattc tcagtgaagt cgagcgacta gcggataaag tcgtgatcat acgcgaagga
     8581 acactcgatg aagaaggaac actcgatgaa ttgcgtcatt tgactcgttc gaccatcact
     8641 atagaaacag aagcagagaa tagtcactta gcacaattga acggtgtcca tgactttgtg
     8701 caaaaaggtc acctcgctca atttgctgct gataacgaag ctttcgatgt gattttagct
     8761 gaagcgtcca aattaggtgt gaaaaaattt gaatctattc caccgactct tgaggattta
     8821 ttcatgagac attatgaagg atgaggagga agcgaaatga ctgataaatt ttcacgctgg
     8881 tccacccttt tttctcaaaa ccttagccgt gactggaaaa agatcctgat atggctagtc
     8941 ggtgtcactg ctttttctgg tggttttgtc cctgcgtttg aagaattgac ttccggacaa
     9001 ggattagctg gattatacga aaccttgcaa aacccggcaa tgattgcaat ggtcggacca
     9061 actccagctt cgaatgctgc tgagtatact ttaggagcga tgtatgcaaa tgaaatgttg
     9121 cttttttgca gtttgtttgc tgctgtgatc tctgttttac acgtggtgag ccaaacgaga
     9181 aaaaaagaag aacttggtct gattgaactt attcgttcct ttcgagtcgg acgtcaagca
     9241 aactctttag ctgtcatcgc tgaaagtatt ctgatcaatt tgcttttagc aatatcgatc
     9301 agctgtacga tgattttttt ccaagcggat tcgatcactg cagaaggtgc ttggcttttt
     9361 gggctatctg taggtagtat ggggattttg gggagtgccg ttgcactgtt tgctgcacaa
     9421 ctgatgccaa gttcagccag ttcgaatggt ctgtctttag cgtttttagg tggactttac
     9481 cttctacgag caataacaga tgtagctgat tcctcccttt cgatgtggaa tcctttaggc
     9541 tggtcttatt tgacctatcc atttacaact aacaactgga ttcctttgct ttatttgttt
     9601 ttgttcagtc taatcttgat aatcagttca tttgttttag aggaacatcg agatttgaac
     9661 accggctata tccccgaacg tgaaggaaaa ccgtatgcta aacgttctct tttatccttg
     9721 cgtggtttat tattctatct aaataaaggg atgacaatca gttggcttat cacttttggt
     9781 ttgatggggg cggcatacgg ctctatctac gggaatatgc aacagttttt agaaagtaac
     9841 gacttaatga aacagatgtt tatccaatct ggcgtctcaa ttgaaaaaaa ctttacaagc
     9901 acgatcatgg tagtcttgat ttgtctagct gctattttac caattgctag catcaatcgt
     9961 ttatttacag aagaaaccca cggacgtatg aatcagctgt tcgcaacaaa aatttctagg
    10021 aaccaacttt attggaccaa tatgttacta gctattctat ttgctatatt ggcaatcctg
    10081 attagttctg gtgcactagg gctttctgct ttggcttcga tgaaggatgc gaaagacatg
    10141 gatctattga tgtttcttaa agccgggttc aatttcctgc ctgccgtttt agtgtttatc
    10201 ggaattagtg gctttctatt cggatggctt cctcgaatcg gtaaacttgc ttatatctac
    10261 ttagcttact cctttgcact caattacttt ggcggaattt tggatttacc agaatggttt
    10321 tccaaaacag ctgtccctag ctgggttcca cggatgccaa acgattcttt tgatctttcc
    10381 gtgttcctta cgttatcatg tatcagcctt gcactgttcg tccttggttc tattggttat
    10441 aggcgaagag acttactaga aggataataa aaaagcatgt acaatttcat gctagcctcc
    10501 aaatctgggt caaaaatcca acatttggag gtcatttttt tatttacaag tcttctaact
    10561 gctctttatc aatgatccag acttctcgat tctttctttt tacataacca ttctcctcta
    10621 ataatttaaa ttttctagat aaagtttcgg gggtcgtacc gataaatgca gcaagttctt
    10681 tcattttcat tggcaggaaa aagtgatcct tccctgtcgc tttagctaag tcaagcagat
    10741 agacagcgac tcgttcttct actttttcca tcatcaaaaa agttgtctgc tgctgtactt
    10801 ttgttaattt ctcaacgttg attgctaaaa gtttcagact aagggcggga taatgcagta
    10861 agagttccga gaaatctttt tgtctcaata tgcaaatttc cgttttttct agtgcttcgc
    10921 caaataaaga ctcatttgga acgcctagca actggctctc tccctcatat ccgcccggct
    10981 ctattactcg taaaagctgt tcctttccgc tagcagataa ttgatacact ttcatactgc
    11041 cggaggccac gatcactaat tgaggttctc cattcggcgc aagaatctgt tctccttttt
    11101 ccacatagtg atgtttgaca agtgcgtgta ctttttcttg atcttgctgt actaagtgat
    11161 tgaacaaagg aacaaatgaa acacataaat gatcatgact cataatctct cctccttcta
    11221 aacagctatt tctaataaag aaacataact tcccttattc caactgataa ttttctttta
    11281 tcatagcata aacgtcaagc gaaccagata ccagcaaata gagtggattt ctttttgtcc
    11341 cttgctttat tttccttctt ttgagacctt aagtaattga ttcctatcaa ttttttaaat
    11401 atttactttt t
//
LOCUS       DADGHT010000095        11072 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.096, whole genome shotgun sequence.
ACCESSION   DADGHT010000095 DADGHT010000000
VERSION     DADGHT010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.096"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            130..1416
                     /gene="efmA"
                     /locus_tag="JX887_002308"
     CDS             130..1416
                     /gene="efmA"
                     /locus_tag="JX887_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAX1258251.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(1554..2153)
                     /locus_tag="JX887_002309"
     CDS             complement(1554..2153)
                     /locus_tag="JX887_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAX1258252.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            2557..3678
                     /gene="mnmA"
                     /locus_tag="JX887_002310"
     CDS             2557..3678
                     /gene="mnmA"
                     /locus_tag="JX887_002310"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAX1258253.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            3924..5345
                     /gene="arcD"
                     /locus_tag="JX887_002311"
     CDS             3924..5345
                     /gene="arcD"
                     /locus_tag="JX887_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAX1258254.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            5359..6477
                     /locus_tag="JX887_002312"
     CDS             5359..6477
                     /locus_tag="JX887_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAX1258255.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(6537..7829)
                     /locus_tag="JX887_002313"
     CDS             complement(6537..7829)
                     /locus_tag="JX887_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAX1258256.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            7979..8539
                     /locus_tag="JX887_002314"
     CDS             7979..8539
                     /locus_tag="JX887_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1258257.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            8668..9045
                     /locus_tag="JX887_002315"
     CDS             8668..9045
                     /locus_tag="JX887_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAX1258258.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            8978..11050
                     /locus_tag="JX887_002316"
     CDS             8978..11050
                     /locus_tag="JX887_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAX1258259.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
BASE COUNT         3571 a         1986 c         2398 g         3117 t
ORIGIN      
        1 tttctaagta aagaaattta aattgaaacg attgttattt agggaaaaag gtattttttg
       61 aaaaaagaat cccgtataat gattgttgtg caaacgctat acaaaatgaa aaagaaaaga
      121 gggatgttta tggaaaatga acagtcggtc gttttaacga attggaagag aaattatttg
      181 ttctttttat cgggacagtt tttgtcagga atcactagta tggtcgtcca atatgcgatc
      241 atctggtatt tgacaagaga aaccggttcg gcgacaattt tgagttttgc tactttacta
      301 ggaatgattc ccatggtttt actaagccca tttgtaggac cgctagtgga tcgctgggat
      361 aaaaaagctc ttttgattgt cacggatatt attgtagcga ttttcgcgct tattttagca
      421 gtagtcggaa cgatttcaga atccttcccg atttggctag tttttgtgtc tttgtttatg
      481 cgttcggtcg cacaaacatt ccaaatgcca acgatccagt cgattatgcc gacaatcgtt
      541 ccatcttctc acataacaag gacgaatgga cagttaggaa tggtccaatc agcgaatttc
      601 atcattgcgc cagctctagg tgcggctttg ttttcagtcg ttcctgtcaa ttaccttatt
      661 ttattagatg tattgggggc agtttttggt gtcggcttat tgatttttgt gaagatccca
      721 aaagtttctc ctgaaatatt ggaagttccg cttactattt ttaaagatgc aaaatttggg
      781 ctgcagcaat tgatggataa taaagggtta tggtacataa cgatcaatgg tgcatttgtg
      841 atgctgttgt tcatgccagc aatcagtctg tatccattga tgacgctaga ttactttggt
      901 ggttccgttg gacaggcggg agcagtggaa gtagtctacg cagtcggaat gctcttaggc
      961 ggtgcactga tcagttttat aggaacatgg aaagaccgaa tgaaacctat tattatagcc
     1021 tacatcatta tgggcctgac gatcggtgca agcggattgg ttccaaacga tagtcaaggg
     1081 ttcttgtact ttcttatctt gaatgcagga gcaggttgtg caacgccata tttcaataca
     1141 ctgctgatgg caatgatcca gcagagttat gaatcgaatg ttttaggtcg tgtcttaggg
     1201 aacttcaact ctttgatgaa cctggcaggt ccaattggat tattatttgc aggaccatta
     1261 gctgatcgtt taggggtaga aaaaatgttc ttgttttccg gaatcgggat tttattatgc
     1321 ggaatcgttt tatttttaac gtcagctgcc cgaaattatg ataaagaatt acagaaaaaa
     1381 ctggtaaaag aacaccatga gcaaaaagac gaatagtatg gaatggagtt gtgacagaag
     1441 tcttgttaca actccatttc tgatcctaat gttcctgtgg caataagcct actcaaatga
     1501 aaaatatgag taattatctt tatttgttta atacttgata tagggcagtt ttttcacgac
     1561 ctatcgtact tcctctttgc ttcatagatt tctttgattt gttgctcaga taacggagtg
     1621 ccaaatggta gtttttcctt taagagttct ctttccggtg cgtctacgcc tacattgaca
     1681 tcgttctcga taggtacgct gtaatgatgg atatgtccat gaagattgcg gatagtgtcg
     1741 ttaggcccga gcaacatcgg ataatgagtc aagtaatatt gttgatggtc gaatttaacg
     1801 atggcaccta catcataaaa ataaaatttg ggacttccgt cagtaagcct aggatcattt
     1861 ttttctaaat aacggaaaaa agcgcgactg tcatggttcc ctttgatcaa gtggattgtt
     1921 ccttgcagtt gagtgaccag ttccaaaatt tctgcatttg ctttttcata ttgcggatgc
     1981 atagcaaggt cgcctagatg ataaacatgg tcggtttctt ttattactgc attccagcta
     2041 gtgatcaact gttggttcat ttcatccaca tttgcaaaga gccgcggagc aaagtcgttt
     2101 tttcctaata agcgttcatg gaaaaagtgc atatcactga taaagtaatt catgtatctt
     2161 ttgcctccct tttttcttag agtaaacaaa atcacttatc tgagcaactc ataacatcta
     2221 aaaagaaaag gttgtaaatg agacgtgcag ctttaagcga taagaagcaa ttttgaaaaa
     2281 tagtttttca caatttataa aattattcct tattgccgaa aggctggccc tttttatgag
     2341 tatgccaatt ttttatatcg aatgctcaaa agatgagtga ttttttggtt gactatcatg
     2401 tttgtgtact gaataggtcc agtagaacag tatttttacg acttgataat taagggatga
     2461 aattttcaga aatatgacgt ataatgtaaa atactgaaaa gttgcgacct tcaactcgta
     2521 gatgtttcag aatctaattg aaatgatggt gatatcatga cagacaacag caaaacacgc
     2581 gttgtcgtag ggatgagcgg cggtgtcgac tcatctgtaa cagcactttt gttaaaggaa
     2641 caaggatacg acgtgatcgg aatattcatg aaaaattggg atgacacgga cgaaaacggt
     2701 gtatgcacgg ccacggaaga ttataaggat gtagcgaaag tagctgctca aatcgggatt
     2761 ccttattact ctgtgaattt tgaaaaagaa tattgggatc gtgtatttga atatttccta
     2821 gccgaatacc gcgcaggacg tacacctaac ccagacgtga tgtgcaacaa agaaatcaaa
     2881 ttcaaagcat tcttggatta tgcaatggat cttggcgccg attatgtagc tactggacat
     2941 tatgcgcaag tcactcgcga tgaaaacggc gtggtccaca tgcttcgtgg agtagacaat
     3001 aataaagatc aaacttactt ccttagccaa ttatcacaag aacagctttc aaaaacgatg
     3061 ttccctctag gcggcatgga aaaatcagaa gtacgggcaa ttgctgaacg cgcaggcctt
     3121 gcgactgcta agaaaaaaga ttcaacggga atctgcttta ttggtgaaaa gaacttcaaa
     3181 caatttttga gcaactatct gccagcaaaa aaaggaaata tggtcactct tgatggtgaa
     3241 gtcaaaggac aacatgctgg cttgatgtat tatacgattg gtcaacgtca aggactaggg
     3301 atcggtggcg gaggagattc gcaagaaccc tggtttgttg taggaaaaga tctagcgaca
     3361 aacacattat atgtggggca agggttccat catcctgcat tgtatgccac aagcttggat
     3421 gcaagtgaaa tccactttac gacgaatgaa ccaatgccaa aagaattcaa gtgtacagcg
     3481 aaattccgtt atcgtcagca agacgttcct gtgacagttc gcttattgga tgataatcgt
     3541 gcagaagtcg tattcgacga acctgtacgt gcaatcactc ctggacaagc agttgtattt
     3601 tatgatggaa tggaatgtct gggtggtggt ttgatcgacc acgcatatca agaaacaaaa
     3661 gttttacaat acgtttaagc gatattaaat gaatcaaaac agctatggct aacaaaagaa
     3721 acaccttttc ttttggatag catagctgtt tttttgcaat aaaattaatt tttattcatt
     3781 ttatacttga aatacttgtg taaaaagttc ataatatcca ataatatgaa taaagttgct
     3841 ttttgttaag caagagcagt tgcaaaatag aagggaatct tttgcaagtg atttgttcaa
     3901 ttttataagt gagggtgatg gaaatggaaa agaaatcgac gggtattagc aaatggggac
     3961 tggttgctct ggttgtcagt tcgtcaatcg gaagcggtgt gtttgggatc acaagtgatc
     4021 tggctagttc tgcagctcca gggccagcga tcctttcatg gataatcgtt gggattggta
     4081 ttttagcttt ggtattatcg ctgaatcatt taggagaaaa gcgtccagat ctagatggtg
     4141 gtattttcgg ttacgcggaa gcttcatttg gtaaattagg tggcttcatc agtggttggg
     4201 gttactggtt gtctgcgtgg ctgggaaatg ttgcttttgc aacgatgctg atgagcgcca
     4261 tgggagaatt tttcccgata ttcaaaggtg gacaaaatgt tccttctatt ttatttgcaa
     4321 gtatttttat ttggggtctg actttattag taaacaatgg agttgaagga gcgagcgtca
     4381 tcaatacaat cgtgacgatc tgtaaattag tgccattatt cctattttta atatttgtat
     4441 ttatcgcatt taaagtgaat atattcactg ctgatttttg gggtaacgta tctgataatc
     4501 tagtgaatgg aacagggcag caaggaacga tctggttgca gattaaaggt tgtttgatgg
     4561 ttatgatgtg ggtctttgta gggatcgaag gcgcaagtgt tttagccaac cgcgcgaaga
     4621 aacgttcaga agcccagcaa gcatcgatca ttggtctgct ttgtttattg tttatctata
     4681 tccttgcttc gatcttgcca tacggcgtct tatctcaaga agagttagca actatttcac
     4741 aacctgctat ggcaaatatt ttaaaaggaa tcgtgggaaa ttggggagca gcgctgatca
     4801 atatcggctt gattatttcg atcattggtt cttggttgtc ttggacgatg ctcccagcag
     4861 aaacaacgat gttgatggct cgagacggtc tgttgccgaa aggttgggga aaaacgaata
     4921 aaaaaaatgc cccaacttat tcgttagttg ttactgcaat cttgactaat ctattcttat
     4981 tgactttctt agttactgat tatgcctatc aatttgccta ttctttatgt acagcggcaa
     5041 ttttgatttg ttatctactt gtcgggatct atcaagtcca gttttcttta aaagaaggaa
     5101 tcaaaaaaca agtagtgatc ggtgggattg ctgtagtttt tgaattgatg ggcatcattt
     5161 tagcaggatt ttcttatgtc cttttatgta gtattgccta tcttcctggt ttttgcttct
     5221 actggatcgc ttgtcgtgaa accaaacatc aaattacggg aaaagaaaaa gtaatgattg
     5281 ggctgatttg tgtggccgca ctgctttcaa tcgggttgct tgctgtaggc tggatcaaga
     5341 tataaggggg aaagaaacat gaaaatcgca aatttcggtg tagaagaatg gctaaataaa
     5401 tgggaaaaga aagcggtata tgatattgca caaagctcga tcgaagcatt gacattagac
     5461 gaactcgttg gcttagatgg gactagcgta agtaaatttt tcgaaaaacg caaaaacgaa
     5521 ccattggact atggctggat cgaaggatca gatgttttca aacaagaagt cgcttctctt
     5581 tatcaaaccg tcgatccgga aaacatctta caaacgaatg gagcgactgg tgctaatctt
     5641 ttagctctat acgcgttagt ggaagcagga gaccatgttg tttcgatgct tcctacttat
     5701 cagcaattat atgacatccc caaatcttta ggtgccgctg ttgactttgt tcatttgaag
     5761 gaagaagaag attggcagtt tgatttagaa cagctagaag ccttagtcaa acctgaaaca
     5821 aaaatcatct gtttgaatag tgcaaacaat cctacaggca cattgctaga tcggaaaact
     5881 ttagaaaaaa tcgcagaaat tgctcgtaca gtagatgcat atgtattgat agatgaagta
     5941 tatgcgcctt taacggataa aggtgaattc ttgtcgatcg tagatgtcta tgaaaaaggt
     6001 atagcaacca attccctatc caaaacctac tccattccag gtattcgtat tggctggaca
     6061 gctactggac ctgagttggc agaagttttt cgaaagtatc gagactacac gatgatttgc
     6121 ggcggagtcc tgtcagatga tcttgctgta catgcattga agaataaaga aaaaatattg
     6181 gcgcgaaaca aaaagatcat tacagagaac cttgtgattt taaaacaatg ggtagccaat
     6241 gaaccgaaag ttgaacttgt cgctcccaat tacgtctcta cttctttcat taaattagcc
     6301 atcgaagaag atgaccagac attttgtatc aatttattag aagaaacagg agtactatta
     6361 gtaccaggaa gtgcctttga tttaccgaag catgcccgac taggttactg ttgtaaaaaa
     6421 gaaaccttgg aaaagggatt attcctctta tctgagttct tgaaaaaaca ggcctaaaca
     6481 aaaacactgc aaggacagtc tgtgacaact gttcaagcag tgtttttcat ttacgcttat
     6541 tgtctatgag aaggagagtg ccctgaagct atggagactc ctgaagcttt ttcttctgca
     6601 gtttcttgct gatggatctc ttgtgtattg tgtcgtacaa gcaagaagtt gaccaaaaca
     6661 agaagagaag tcgaaagaaa gacgccgcga taaccaaatg cactggaaac actggagccg
     6721 atcataggcc ctactacgtt accagttgct tggaaagatt ggttataact gaagatccgt
     6781 ccagcagctt gatgaggcga atattttgtg atcaatgctt ggacagcagg gagcagacaa
     6841 gcatcagaga taccaatcaa aaaacgtaag gcagctaatt gccaaacatt cgtgacgaat
     6901 gccattggga tataaaccag aatcgcaaaa cccaaaccaa tcgcaagtat tctttcactc
     6961 ccaatcttgt cacctaagcg accaaatctt ggagcggcta tcaaagtggc aatcccaggt
     7021 atcgaagcaa tgattccgct gatcaacgta acattcccat gtccatgcag caattggcga
     7081 atgtacagac tgatgattgg actaatggaa ttgttggatg cttggatgat catcgttgtg
     7141 acgaacatac cgatgacgac gtgtggatat ttcaagtctt tgaaaatctg tttggcagaa
     7201 accatgtttt cttttttcac tgggacaaat ttttcatgga cgaaaaacag actcaacaag
     7261 aagacgaaaa ataagatgat ccctgtaatg aaaaaggtag ggcgatagcc aaacgctgaa
     7321 gcagagatcc cgccaagaag cggtccaagt aatgttcctg taacagaacc agttgctaag
     7381 gttccaagaa cttgaccact tttttctttt ggcgtcccag ttgcgacaag ggcagtggca
     7441 ttactgatat aaccagaaaa aatcccttga agcagacgca atgcgactaa ttgatacaca
     7501 ctagtcacgc aacccatcaa agaaatgacg attgccattc ctaatgaagc acgcaacagc
     7561 atcaattttc ttcctttttg gtcggctaat tttccccacc aaggagagat aagcgtagtc
     7621 accaagaaag tagatgaaaa agtcaatccg ctccaaaagt tcaattgtga cgtactataa
     7681 ttacctaacg tatctatgta aagtgacata aaaggcatga ctaaactaaa tccgatacca
     7741 gccataaatg ttccaaacca taagacaaac aagttttgtt cccaagtttc tcttttccta
     7801 aataattttt cctttattct tgcagccaat tagactcctt ctttctgaaa attttcatct
     7861 acagctcttt attataaact acaatatgta gtttatcaat gaaagtctct tttttctctt
     7921 tctttttcgt ggtaaactga aagagtgaag gatttatttt atgagaggaa acatggaaat
     7981 gaaaaaaaga aatctgtctc aagagaaaat catcgactgc tttcgagaac tagcagaaga
     8041 gatggatgtt cagcaaataa cctttcagca tttagccaaa cgcttggata tcaaggctcc
     8101 ctcgctgtat aaccatttca aaaatattcg tgatgtcaaa acagcgctaa cagcgaaact
     8161 tctgcaggaa cttaatgacc agctgcgacg ggctcttgtg ggaaaaagtg gtcaggaagc
     8221 actgcagatc tatgcagaaa cttatcgatc ctttgctttt tcaaatcaag cagtgtatga
     8281 gttactgatc agtgtaccgc ataccaatga agctgtttta ttagatggaa tccatgaaac
     8341 gaatcagatc attttgcaga tatttgaggc ttttcaatta acgaaagaag aaaaagttca
     8401 tcgaagcagg gaacttcgta gtatgatcca cggttatctt tccttacgtt ttttaggata
     8461 ctttacaaaa gaaccaacaa tcgatccaga agacagctat ttttggatga tcaataactt
     8521 tatcgctact ttgccttaaa caatcagatt catttgtaac aattttaaga tgttcattaa
     8581 atgacccttt tataagagaa aattcttgca actttcttga aaagtgacta agatgagtct
     8641 agaaaagctg aaagaaggag cacgagtatg tatcaagtaa ttaccatgtt cggggacaat
     8701 gagccttggt ggttttttga agactgggaa gaagatattg aagaagaaga aacattcgag
     8761 tctttcgaag aagcacgaca agcgtacgaa aaacaatgga acgaaatcca tcaaaattat
     8821 gaatatatca atgcaaaaag taactttctc agcgcctttt ggaatgacgg agatgagcgc
     8881 tggtgtgaag agtgtgacga tgatttacag caatacaagg gacttgcgtt gttgaaaaat
     8941 catcagccca tcacagtaga aagcagaaag gaattttatg aaacaactaa ttctagcgga
     9001 aaaaccaagc gttgcgaaag acctaagcaa ggtgcttggt gctaatcaaa agcacaaaaa
     9061 ttattatgaa ggacccaagg tgatcgttac ttgggccctt ggtcatttat taggattgaa
     9121 aatgccggaa gatctgaata aggaatggca gagctggcaa atggacacgt tgccaatgat
     9181 ccctaaaaaa ctaggaatca aaccacttcc taaaacagga catcaattaa aagcaatcaa
     9241 gcagctggct cagcgaaaag atgtctcaga agcagtcatt gcgacagatg ccggaagaga
     9301 aggggaactt gttgctcgct ggatcttaga gtatgtgcat ttcaataaac cagtgaagcg
     9361 gttatggatc tcttctcaaa cagataaagc aatcaaaact ggattcaagc aactaagacc
     9421 tgcgaaagaa tatgatgcat tgtatgaatc tgctcttgcc cgggcaaaag cggactggct
     9481 ggtaggattg aatgtgacca gagccttaac tgtgaagtac gcggataatt tatcagcagg
     9541 ccgtgtgcag acaccgacac tagcattagt gagagaccaa gaaaagaaaa tcgagcagtt
     9601 ccgtccacaa acgtatttca cgatcacgtt gcaagctgga aaagaacaag ccaaaatgct
     9661 tcaaaaaaat caatttgctt taaaaacaca agaagaagca caaaaacttg ttcaattgat
     9721 cagtacaagc aaaggaactg tcacagaagt ccaagaaaaa ttaaaaacgg aatctgcgcc
     9781 attgccttat gatttaacag agatccaaag agaagccaat caacgctatg gctattctgc
     9841 aaagaaaaca ttaagtcttg tacaaagttt gtatgagacc cataagatcg ttacttatcc
     9901 gcgtacagac agcaaatatc tgacaaatga catgaaaagt acgatgaaag aacgattgca
     9961 agcagtcagc gactttgctc ctgaggtcaa gcagtatttg aaaaacggag ccatcgtcca
    10021 acagacaaaa gtattccaag acagtaaagt gaccgatcac catgcacttt tgccaactga
    10081 aaacagagca cgttatgaaa aattaagtaa tgaagagcga aaaatctatc aaatgattgt
    10141 ctctcgtttt ttaggactgt ttgctcaacc ccataaagtc agccaaacaa aagttacggt
    10201 tgaatttggt aaagaacgat tcatttttcg gcaaaatcgt gtcgtccaag caggatggaa
    10261 aggcgaaact gaaactgaga cggaaacagt caaatgggaa aaaggaatga gaatcaatcc
    10321 cgatttcgcc atcaaaaaag aactatctgc accgcctaaa ccattgtcag aagcaagctt
    10381 gcttggtcaa atggaaaaat acagtctggg aaccccagct acgcgtgcag agattatcga
    10441 gaaactaatc aaatctgaac tgatggaacg tacccctcaa ggactgcaag tatctcctaa
    10501 aggtaagcaa ttattagtat tggtaaatcc ctctttagta acaccagatt tgacagaaag
    10561 ctgggaaaaa gaccttgaag ctattgctgc aggaaagaaa caagcaggaa ccttcttgaa
    10621 tggaatcgaa aaagaaacaa aacgcttggt gaatgagatc aaatcaagca aacaagaata
    10681 tcaagatttc tcgattaccc aaaagaaatg cccagaatgt ggggccaatc tgcgcgagaa
    10741 aaacacacgt gacggcaaaa tctatgtctg caccaattca gattgcaact accgcagaag
    10801 aaaagatcca aaagtctcta atcatcgatg cccgcaatgt caccggaaaa tggaaatcat
    10861 cgaaggtaaa aacggtgctt atttccgttg taaatacgat ggaacgacag aaaaattgct
    10921 tgataaaaaa gagcagaaga agaaaatgac caaacatgaa gaacgacgct tgctgaaaaa
    10981 atatgcacaa gcagaagaac cagaagaaag cccattagca gcagcactaa aagcagcaat
    11041 gaagaagtaa taagatatga aagaggttgt ga
//
LOCUS       DADGHT010000096        11036 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.097, whole genome shotgun sequence.
ACCESSION   DADGHT010000096 DADGHT010000000
VERSION     DADGHT010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11036
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.097"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            949..1422
                     /locus_tag="JX887_002317"
     CDS             949..1422
                     /locus_tag="JX887_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAX1258260.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="JX887_002318"
     CDS             1431..1658
                     /locus_tag="JX887_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1258261.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2294..2665
                     /locus_tag="JX887_002319"
     CDS             2294..2665
                     /locus_tag="JX887_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258262.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2921..3163)
                     /locus_tag="JX887_002320"
     CDS             complement(2921..3163)
                     /locus_tag="JX887_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAX1258263.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3195..4097)
                     /locus_tag="JX887_002321"
     CDS             complement(3195..4097)
                     /locus_tag="JX887_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAX1258264.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4110..4298)
                     /locus_tag="JX887_002322"
     CDS             complement(4110..4298)
                     /locus_tag="JX887_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAX1258265.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="JX887_002323"
     CDS             complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="JX887_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAX1258266.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4913..5806)
                     /locus_tag="JX887_002324"
     CDS             complement(4913..5806)
                     /locus_tag="JX887_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1258267.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5884..6822)
                     /locus_tag="JX887_002325"
     CDS             complement(5884..6822)
                     /locus_tag="JX887_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAX1258268.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6856..7206)
                     /locus_tag="JX887_002326"
     CDS             complement(6856..7206)
                     /locus_tag="JX887_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAX1258269.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7239..8141)
                     /locus_tag="JX887_002327"
     CDS             complement(7239..8141)
                     /locus_tag="JX887_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAX1258270.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8134..8991)
                     /locus_tag="JX887_002328"
     CDS             complement(8134..8991)
                     /locus_tag="JX887_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAX1258271.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9325..10134
                     /locus_tag="JX887_002329"
     CDS             9325..10134
                     /locus_tag="JX887_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1258272.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10174..10671
                     /locus_tag="JX887_002330"
     CDS             10174..10671
                     /locus_tag="JX887_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAX1258273.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
BASE COUNT         3232 a         2059 c         1853 g         3892 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt
     2041 aagctcccat atatactgta aagccttcta tatattatgt catgttgctt tttaacattt
     2101 actatgtagt tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt
     2161 aacattattt tgataataat gattatttat ttaaaaatac attagataac atttgttacg
     2221 acacgaaaaa gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat
     2281 taggaggaat agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat
     2341 tccattacca acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc
     2401 tgctcttacg aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta
     2461 ttggctaaaa cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct
     2521 ctttgagttt ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat
     2581 catctgggtt ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa
     2641 atttagggag gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag
     2701 gaaaaacttt taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa
     2761 gtcttgtcac agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat
     2821 atgcccaacc aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     2881 tgaagaacag ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga
     2941 atgatacgat tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg
     3001 caatacttgg tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg
     3061 ctacgacatt tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg
     3121 ctccgataat tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat
     3181 gttttacttc cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg
     3241 cttccagctg ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc
     3301 gctgcgtcag ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt
     3361 ttgatgtcca ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact
     3421 tctttgccga ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc
     3481 acaatgacat ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc
     3541 gttacattat ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca
     3601 gataataaac cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct
     3661 tcataattca gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta
     3721 tttgtatgat cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct
     3781 tgtgctttcg catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt
     3841 gcatcatgtt gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt
     3901 tctgcatcat gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga
     3961 tgtgcagata ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt
     4021 gtcgttgggt ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt
     4081 ttgttattgt tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc
     4141 gtttgtttca gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag
     4201 gtcttgaaaa agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag
     4261 atgataggga gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac
     4321 tcgtttgcgg tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac
     4381 tttcactggc tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa
     4441 tgttcctgtt ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc
     4501 gatcttgttt ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg
     4561 caagtgagaa cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc
     4621 atgtttcagt agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat
     4681 aattgtcaaa atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt
     4741 agtgatggaa aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa
     4801 tagtatcgca aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt
     4861 tacaccttta ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt
     4921 tgatcgcttc tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg
     4981 atgctaagaa aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac
     5041 tttgctgacc aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg
     5101 tccagattgg accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg
     5161 ctaaaccgat cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt
     5221 cgcttggatt gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat
     5281 gcggaacagc ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt
     5341 tgacttgctc aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta
     5401 gtaccatcgt atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg
     5461 cttgttcgtc acgaagatca aaaggtagta agacaatctt acgtcctgca actttcacgt
     5521 attttgctac ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg
     5581 ccccttctct agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga
     5641 ttagtacacg gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag
     5701 gaacaggaat catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct
     5761 ccgtatggta caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc
     5821 tagtttttaa attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat
     5881 tctttaattt gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa
     5941 agagccaaag actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt
     6001 attcattccc caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc
     6061 tagatatttc atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat
     6121 actctctaat aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg
     6181 gacatcatag agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa
     6241 ttgatccatt gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc
     6301 aagatctgcc tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa
     6361 agcgtcaatt cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa
     6421 taatgtatac gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag
     6481 ccgatccaca aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac
     6541 aaaagatatt ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac
     6601 taccaaagaa aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc
     6661 ttccggatat tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg
     6721 ctcaatctct tcgggctttg cactatcaag tacgagccaa ttatattttt tttcatctgt
     6781 ttctattaca ttcttttctt catccacaaa gtagtatctc aatgtatacc tcctttttgg
     6841 actttctcga aactattagc tgaagaagca gttctttaat ttgatattat aatcgagtac
     6901 tgcgatttca ttttctaatg aaaagctgtc aagctgtttg ttgaagtcca tgttcaatcg
     6961 tttaccgaaa taattttgct ctaatttaga tgtatagatg tccaataatg gatgctcgat
     7021 tttagtcgca tattctccaa attccgaaac aaaaggaatg atttgaaaaa agctgccttt
     7081 tgcaaaagca cctttgtccc ttagaaatgg atcggaatca ttgataagcg cgagtgcgat
     7141 ttttgtattt tccccaacct tttcaattaa cgtctctact gcatttttag acattgtaat
     7201 ttccattcct actccccctc ttcagttgtt gtcttctatt atttaacaac tacatctgtt
     7261 tttggttgaa cttttgcata ttttggatat ttagggaatt tagctacaca acggaaagcc
     7321 gtcatccctg catatttttc gtaatatttc ttcgttggcc cttcaaaatc cttgctccac
     7381 ggtttcacat gtcctgaaaa atggataatg taaggattgt tgcgagtttc ttcgtattca
     7441 cgttcacctg ctgctgttgg atgttttttt gcttttgcca tgatatagcc ttgtgcattc
     7501 caacgcggat gaagtggtaa ccaacggtca tgtaagatag catttaatgc atcttggtca
     7561 tggaatcgta atttttctgg attatgttcg atgaaatcta atactttttg cgtaatattt
     7621 tcatctaacc attttttcac attgatcagc atcaaacctg agttgaaata acgcattgat
     7681 ttagctgaaa ttttcatttt ttccagtcgt tgatggaacc cagcgtcttc aacagctgct
     7741 acgattgaat caccgaagtc aagacgccat aatttagaga tatcttgtaa agcgatcatg
     7801 tcgcaatcca tatataagat acgttcaact tctgtgccgc ggaacaattc cggaatcgca
     7861 atacgataat aagctgtttc tggaatacga tcgctgatta ccacatttgt aaagaattct
     7921 ttattgattt tcaagaattc cacatctgag ttcattcgtg cgtttttcac tgagaagcgt
     7981 aaaagctgtt tactttcaaa atcgatatca tcgtcaatca catagaaccg aacaaattta
     8041 gacgggttgc aattatctaa tactgagaca aataatgcag ctaaatgtgg tacgaatttt
     8101 gtgttacaac ttgcgactac tgctatttct tttttattca ttgatctcgc ctactttcgt
     8161 tagagtactg tgtgctaatt tttttaagta taaattggta tacggatgat ctttcaacgt
     8221 attccaaggt ttatcatgtc ctgtaaagtg aacgatcgaa ggtttttcat ttccttcttt
     8281 atactgacgt tcatattttt catttggtgc tggatgacgt tcaaaaatca gcgaagtctg
     8341 catgttccat tttggatgaa gttgttccca atcttcataa agtacagcat tcaaagcatc
     8401 ttggtcgtga tagatgattc gatcgccatt ttcactgagg taatggatag ttttttctgt
     8461 aatttctttt ttattccatt gatcaatgtc aatcaccatc actcctgaat tgaagtacaa
     8521 gtcatcggaa tcgattccta atctttccaa agctttcact tggcctggat cgataatagc
     8581 gccgattgtt tttccattta acggctcatc atatagtttt acgatatcgt ctagtactaa
     8641 cacatctgaa tctaagtaaa ggactttctt ataatcctct ttagctaata agtttggtaa
     8701 agaaattctt aagtaagcgg tagttgtgat atggtcactg actaggaagt cttcgtagat
     8761 atctttttcc actgtcagga attggatact tgcattactt gaatatttat ttaccgtttc
     8821 ttccaatcct tctttactat attctgatag accatcgtca atcacataaa attttatgcg
     8881 tcttgtttta ttgcaatttt ctaatgcagt tgcgatcatc acgctcaagt aaggagcata
     8941 attttcgtct gaagcagtta ccacaggaac tacgccgtat ctcttctcca tcaaaatcac
     9001 tcctttttct aatctttttc taacctgttc tacatctaga atattcctca tttggtttta
     9061 aagcaaaata tatgctttgt tttcattgaa tattttaaaa tttttttatc acaaaacgca
     9121 tcggtaagcg ctaactattc gtttttcatg gctttttatt caaaggtatt gaccaaaaac
     9181 tactatatat agccaccttt ttcttaagaa tgttttttga aaaaattcat aatgacaaag
     9241 caagttagtt tcattttttt aaattctcat ttaatcttaa ggtaacagga aaatagatat
     9301 gtaaaaagaa agtaggaaga taaaatgaaa ctagcagcga ttgatttaga cggtaccttg
     9361 cttgatcgaa atggaaagat accagaagaa aatatccaag cacttcggaa atttgatgaa
     9421 aatggcggaa tcgtaaccgt cgctaccgga aggaacagca tttctgctaa agatattttt
     9481 tccgaattag gaatcggtgg ctatttgatt tcttccaatg gttcactgat tgctgaaatg
     9541 aaggatggaa aaatggcgaa agttctcaga cgttcaaaaa tagatagcga tacactgaga
     9601 aaagccttct tctatgctca agaagcgaaa atatccatca ttgctagccg agaaacccaa
     9661 gatgatcagc tgacattcga tgaatcaaat ctagtcaaag atgaccctta ttatgaacat
     9721 ttcaatttac agaaccattc ttttgatcaa attttaaata tgttggaaga tccttctctt
     9781 agctatctta aattagcatt aacagataag agtgaagaaa aactacagaa gctacaaaga
     9841 gatctgcaag cagatggtat ccaatcagta ttctctgatc cgcatttctt agaaatcacg
     9901 cctacaggta tcactaaagc tcattcactt gtttttctgg cggattacct tggaatcgaa
     9961 tcgagtgaca tcatggcttt tggcgatcaa gaaaacgaca ttgctatgtt gaattacagc
    10021 gggttgagta ttgcgatggg gaatgcacag cgacaagtaa aagaaattgc aaaccaagta
    10081 acactgacga atgaagaagc tggtgttgct tatattttaa aaaacttcta ttaaaaagaa
    10141 taaaatgacg atatgaatgt aggaggaaag aaaatgttag ttattattga tatgcaaaat
    10201 catattcttg atccaaacag cgaattttat attccagagt cagatcaatt ggcagaacgt
    10261 attgctcaaa gattagctaa agcacgccaa aataatgaat atattctctt cacacgggat
    10321 ataccagttg aactgaagga caaagaagaa gaacgagaag atttgcaatt gatccctctt
    10381 ctttctccac aagaaaatga acgagtgatt aaaaagtatt actttacgat tccacctgaa
    10441 actttagctg aaatccagga aactttattt gaaagcaaag aagaacaaaa agagatcgaa
    10501 gtagtcggga ttgaaacaaa cttgtgtgta ctctctaatc tgataggcct gcagagtgct
    10561 tttcctgaag cagacttttt tgttgatcca atgttagtct ccagtagaaa acacggagaa
    10621 tccgctttag agctgttgaa agatttcaac gtctctatcg tcgaatcata aaaatatcta
    10681 tcttcattta cgatatttaa cacacaataa aaaaagcacg cagaactgtt ttagtcctac
    10741 gtgctttttc tatcaaagta gattggcttt tttatgacac agagtgaaac ggcaggctca
    10801 cgacctcttt cttaaatggt gttcaatcag ctgaccctcg gtattagctt aacaaacggc
    10861 aaaatatgag gaactatttt tccgtttgtt aagctaatac tcaggtcaaa acgctgattt
    10921 cacaacctct tccttaaacg gtattcaaaa gcttgcatct gcagtaataa gaacagccaa
    10981 gtaaaaacat aagaagctgt ttttacttgg ctgttcttat tacttgatgc agggca
//
LOCUS       DADGHT010000097        10469 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.098, whole genome shotgun sequence.
ACCESSION   DADGHT010000097 DADGHT010000000
VERSION     DADGHT010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.098"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            21..644
                     /locus_tag="JX887_002331"
     CDS             21..644
                     /locus_tag="JX887_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258274.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1094..2143
                     /locus_tag="JX887_002332"
     CDS             1094..2143
                     /locus_tag="JX887_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1258275.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2140..3021
                     /locus_tag="JX887_002333"
     CDS             2140..3021
                     /locus_tag="JX887_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1258276.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3024..3794
                     /locus_tag="JX887_002334"
     CDS             3024..3794
                     /locus_tag="JX887_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAX1258277.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4073..4927
                     /gene="aroE"
                     /locus_tag="JX887_002335"
     CDS             4073..4927
                     /gene="aroE"
                     /locus_tag="JX887_002335"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAX1258278.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5105..6268
                     /locus_tag="JX887_002336"
     CDS             5105..6268
                     /locus_tag="JX887_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAX1258279.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6385..6795
                     /locus_tag="JX887_002337"
     CDS             6385..6795
                     /locus_tag="JX887_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAX1258280.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6969..9197
                     /gene="topB"
                     /locus_tag="JX887_002338"
     CDS             6969..9197
                     /gene="topB"
                     /locus_tag="JX887_002338"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAX1258281.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9335..9652
                     /locus_tag="JX887_002339"
     CDS             9335..9652
                     /locus_tag="JX887_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258282.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            9812..10048
                     /locus_tag="JX887_002340"
     CDS             9812..10048
                     /locus_tag="JX887_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAX1258283.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10045..10443
                     /locus_tag="JX887_002341"
     CDS             10045..10443
                     /locus_tag="JX887_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAX1258284.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3646 a         1763 c         2220 g         2840 t
ORIGIN      
        1 gagaaaaagt agaaaagaag gtgtttgtta tttgggaagt agttaaatcg agagtacaag
       61 aaatgaatga acatttctca gtgtcattcg cagaaaatcc aagtaagtat tttcgacgtc
      121 ttgtttttct gctcatctta tcattgctgt taacagttgc aatgttttta ttgccggaaa
      181 aaatccgaga agagcaagta aatagtctcg tttattcgtc cataccaacc agcaaattga
      241 aaccttttga ttacagcaaa gctgatcaga aaatcaaaca aagccgggcg atatcggtga
      301 tgttcagcaa accgaacggg aaaacctatc aggacatgct tgatgttttt aatgatcctg
      361 agcttatgga agaattgaat cgaccgatct tttattatcc gatcgtttat gatgtacatg
      421 aactggaaca aaaatataac atacgaacgg atgaagtgac atttattttc tttgatggag
      481 gaaaagaagc aaatcggata actgcgggta agggaggaat aactgatttt gataaggagt
      541 tgatccctga actgaatcga cttccgttag ccaatatcaa acaattagaa gaagaattgg
      601 atagaacggg agtaacttcc caaaattccg agattgctaa ttgagacatt ggcgcgatga
      661 aacggtgggt ctatatagcg ctatttttaa ttatcagaac aagtgatgtt tgatcttcaa
      721 aataacaaat aaaaaattaa aaaatatagt tgacgaaatt caaaaattcg attagactta
      781 aatcaattct taaggaaagg gtgacctgta atgaacttat caaaacgtat ttcagcagaa
      841 aacaaaaaaa attggcgcag ctggcgtaga taagttgtat taatggtgag actttcccat
      901 agatacaact ttttagagtg catttctaaa gcttgtatct atgctagaca tgaacattga
      961 ctgccgcata gattagaatc tatgcggttt tttgtgtaaa gacaatgacc gctttggcca
     1021 ttgtcttttt ttgtagactg gatacttgcc tgattataat aaataaaaag attgactttg
     1081 caggaggaaa aaaatgaaaa acaaacgatt aataacagtt gtagtaatta ttttagttta
     1141 tttagcaggt gcatttattt atggaaaagc ctcaggcgaa aaagaaagta cttcgacgaa
     1201 ccagacaaaa aaaacaacag ttgttggggt attgcaatac gtgagccatc cggcattaga
     1261 tgagatttat cgaggaatca aagatggtct gaaagaagaa ggattaaaag aaggagaaaa
     1321 tcttgagatc aaatttcaaa atggacaagc cgatcagagc aagctagcca caatgagtca
     1381 acagctagta caatctgatc cagatgcctt gattggaatc gcaacacctg ccgctcaatc
     1441 attagcaaac acgacttcat cgatcccagt tgtgttaggt gctgtaacgg atcctgtggg
     1501 ggctggatta gtcgcttctt tagagaaacc tggtggtaat gtaacaggtg tttctgatca
     1561 gccgcctgtt acttcacaaa tcaagcttgc ttctgatttg ttgccaaatg caaaaaaagt
     1621 cggaatcttg tatgcttctt cagaggataa ttcaaaatac caagtagcac aagcagaaga
     1681 agctgcaaaa aaagaagggt tagaatcagt aaaatatgcg gtgccttcca ctaatgagat
     1741 tgcacaaacg gttcaagtga tgagccgaca agtcgatttt atctatgttc cattagataa
     1801 taccattgcc aatgcgatgc aaacagtggt aaaagaagca aacaaagcaa atatccccgt
     1861 cattccatct gtggatacaa tggtggaaca aggtggacta gcaacaatcg ggatcaatca
     1921 atatcaatta gggcttcaaa gcggtaagat ggcggcagaa cttgcgagtg gaaaagaaaa
     1981 accggaaacg acgcctgttt atacatttga tcaaggggat acagtgatca atcaatctca
     2041 agctgatcgc ttaggaatca ttgttcccca atcgatgaag gaaaaagcca aaatcattac
     2101 agatgactcg cagcaagaaa catctaagga ggatgacaaa tgatcgtatc agctatttca
     2161 caaggcatgc tttgggcaat attaggatta gggattttca tgacttatcg gatcttagac
     2221 tttcctgata tgacgacaga agggtccttc ccattaggtg ctgctgtctg tgtgacagct
     2281 attactcatg gggtagcgcc gattgtagct acattattag gcgtaggtgc tggcatgata
     2341 gcaggactcg ttacggggtt actttataca aaaggaaaga taccggttat tttagcaggg
     2401 attttagtga tgtcaggatt gaactcagtt attttgtttg tgatgcgaac accaaatctt
     2461 tctttattga atcatccgat tctacaagac agcttccatc gctttgggtt acctgattac
     2521 tttgacacag tccttcttgg cttcatctct ttgggcatct tgattgctgt actgctattc
     2581 ttcttcaata cagatttggg tcaaggctat attgcgacag gagacaacga aacgatggct
     2641 cggtcgttag ggataaaaac cgatcgtatg aaaattttag gtttaacttt gtcgaacggt
     2701 gtcattgcat tatccggtgc gctgattgcc cagaacgacg gatatgcaga tgtaaataaa
     2761 gggattggcg taatcgtcat cggtcttgct tccatcatca tcggtgaagt gatcttccaa
     2821 gaattgacgc tagcagaaag attgattgct attgttgtcg gcagtatcat ttatcagcta
     2881 ttgattttag tagtaatcaa actagggttt gacacgactt atctgaagtt gttctccgct
     2941 atcatcttag ctatttgtct gatgatcccg caattgaaga aagcactgaa cttaaaaacg
     3001 ggttttgaga aggaggcata gtaatgactg atatattgac aatcaaaaat ggcagaaaag
     3061 tcgtaaacaa tggaatgaat gaagagaaag tactattgga tgaaattaac cttacaatca
     3121 gagaagggga cttcatcact gtccttggcg ggaatggtgc tggaaaaagc acactgttca
     3181 atacgatcgc tggtacgctt caactcagtc aaggatcgat ctcttttaaa gatcagctga
     3241 tcacaaaaga ttcagaagaa aaaagagcac gattcctttc tcgagttttc caagacccca
     3301 agatgggaac ggctcctcgg atgacagtag cagaaaattt gctacttgca caaaaaagag
     3361 gtcaaaaacg gaaattccgt ttacgtaact tgaaaaatca aaaagaagat tttttcagac
     3421 tatgtcaaga agtcggtaat ggcctagagc aacacttgga tactccagcg ggtgaattat
     3481 ctggtggtca acgccaagca ttaagcttgc tgatggcgac gatcacagct cctgagttac
     3541 tattattaga tgaacatact gcagctttag atcctaaaac agctaaagca ttaatgcgat
     3601 taacaaatca gcggatcaat gaacaaaaat tgacttgtct catgatcacg catcgaatgg
     3661 aagacgcctt gaaatacgga aatcgtctga tcgtactcca aaaagggaaa atcgttcaag
     3721 atatttctga aaaagaaaag caacatttga caatgggcga ccttttgcag ttctttgaag
     3781 aagtagtgga ttgatttcga cagaaaaatt cctttcagta gaaggacttg aaaactcatt
     3841 gacatcttcc tttgattcat cctatactta aaacaataaa caattaaaca tatttgggtg
     3901 ttttgtagga tcacgtagtc aatgatttta acaattaaat agaatattct ttgctctgac
     3961 aagtaaacga tgagaaaaga atttgctact ttgccaccta gacgtttcgt actttttcgt
     4021 atcaaacgct aagtggcttt ttttattgaa gtaagaacaa aggaggaata agatgatttc
     4081 tggacaaacc aaattagctg ggctctttgc tgatccggct tctcacagtt tatccccatt
     4141 gatgcacaat actgcttttg aagcaaacaa catcgatgcg gtgtatttag ctttccaagt
     4201 aaatccaatg aatttgaagc aagcagtcga aagtattcga acttttgata tgttaggtgt
     4261 aaatctttcg atgccgaata aaacagcggt tattccttat ctggatgagg taagccagga
     4321 agcgcaattg atcggagcag tgaatacgat cgtgcacgaa aagggtcgtt tgattggcta
     4381 taataccgat ggtgcgggct tcatgcaatc cgtgcaagaa gctgggattt cgatcaaaaa
     4441 gaaaaaaatg actctactgg gagctggagg tgcagcaaag gcagtcactg ttcaagctgc
     4501 gttagacggc gctgaggaaa tcgtagttta taaacgaaac aaccaaacat tcgctcaagt
     4561 aaaagaaaca ttcgaacaac tcagctatcg aacttcttgt aagataaaag ttcgtgactt
     4621 tgccgatacg catcaattaa gaaaagactt gaaagaaagc tgtcttctag tcaatgcaac
     4681 agatatcggg atgggaaaga aaatcaatca gtcaccgctc ttagatataa gcatgatgca
     4741 tgagaatcta gcggtttttg atttgattta tgcacctaga gaaacacgtt tattaaaaga
     4801 agcaaaaaaa gtaggagcaa aaggatacaa tggacttggc atgttgatct accaaggagc
     4861 aatcgcgttt gaattatgga caaaggaaaa gatgccgatc catgtgattg aaaagctgtt
     4921 tgattaaaaa aggataatag ataaagatct tttattctcg cataaacggt ctcaagaaaa
     4981 gtaatccttt atgtatcgaa gcatttattt cgttattttt tattaaatta tcaaaaaatg
     5041 ataggctttt gtcgattggt tatcgtatcc tttatttatc agtaagaaac gaggaggaac
     5101 cacaatgagt cggatggatc gctataagga catccataag aaggcgaaac ctctgaagcg
     5161 ggatacgggg agtatttttg ctagaagaga acgaaaacga acgcgtatgg aaaatgagga
     5221 agatgctacc cgtatttatg aaagagagca gcattcattt gaacatttga accaatacga
     5281 gcaacagata tacagagatg caccaagagc agaagaacaa caaaaaaata aaaaattttt
     5341 caatcggcaa aagaagaaca aaccgttaaa acctcgaaga aagcgatcgt ggaaaaaaat
     5401 cattctatcg attttgcttg ttttgatcct ttattcaggt atctcatttt ttattggtaa
     5461 atatgtagct gaacatgaca caagcttaga ggcagcgact tcagaaacct ttcatgggca
     5521 aaaagcgacg aatggtgcgc ataatatttt gatccttgga agtgatacac gcggagaaga
     5581 tgccgggcga gccgatacga tcatggtctt acagttggat ggtccttccc ataagccgaa
     5641 actgatttct tttatgcgtg acagcttcgt tacgatccca ggggtaggac aaaataagat
     5701 caattcagct tatgcatacg gaggagccga tctagtgcgt caaactttag tagaaaattt
     5761 tggaatcgat tgtcaatact atgcgaaagt cgatttcaaa tcgtttgaaa aagtgatcga
     5821 tgccttattc atgaacggag tgaagatcga tgcagaaaaa gatctgaatc tggatggtgt
     5881 agatattaaa aaaggggtcc agaagatgga tggacatgtt cttttgcagt acgcacgttt
     5941 ccgaatggat gaacaaggag actttggccg tgtcagacgc caacagcaag taatgaacgc
     6001 tattttcagc caattgaaga atccattgaa tctgatccgt gcaccttatg cagctggtaa
     6061 agctttagga tatacatcca cagatgtcac tgcttggttc ttgacgaaaa acctcttttc
     6121 gattgcacga ggagctggtg gcattgatcg aataagtgtg ccagtagacg gttcgtggaa
     6181 ttatgggcaa agtgattatg ctggcagtat tcttgaaatt gataatcaaa tgaatcaatc
     6241 tgctattaca gattttttga ataaatgatc ataaaaaaga tcaagaagaa gctgcgcaag
     6301 gcttttgtca tgaatcaatc aaacgattca ctcgtaaaaa acgctttctt atggtagatt
     6361 taaccaagag aggagctgtt tacattggat atctatctga acttcaaaaa tgagtcgcgt
     6421 gaagccatcg ctttttatga aaaagttttt cagactgaag catcaggtat caccacatac
     6481 ggtgaaatgc ctggaataga acaaatgaac ttgccagaag aagcaaaaaa tctaatcacg
     6541 aatgcacggc tgaacattta tgatacatta gttatgtttg cagatacgcc agaaggaatt
     6601 ggtcctgaat tagttgtggg aaataatgtt tctttagtca tccagacaag aaatgaagaa
     6661 gaaacgaagc gcctatttga aagcttagct gagggtggta agattgagat gccactggat
     6721 gctgttccgt gggctcagtt gtatgggatg gtaactgatc gatttggcat caactggcag
     6781 attaaccaag agtgacagct aaagatgaat attttctgga aacatcaagc agcaaacgga
     6841 tcatcgtttg tttgcttgat gtttttgtgt ctatttcgac tatacggtat ctttttttta
     6901 ttgccagatg cgaaaatatg ttccataata gagaagtccg caaaaaatta agtaacggag
     6961 gtcagaagat gaagacggtg atactagctg aaaaaccttc acaagcaaaa gcctatgccg
     7021 aaaccttcca acagcaaaag cggcatgaag ggtattatga aatcagcgat ccattgtttg
     7081 ctggtgaagt aaccatcact tatggttttg gacatttggt agatatggtt gctccaggag
     7141 cttatgaaga gcgttgggca aaatggtctt tagaaaattt gcctattttc ccagaaacct
     7201 tccgttacga agttccaatg gacaaacgtg cacaattttc gatcgtaaaa cgagaattgc
     7261 agtcagccga taccatcatt attgcaacag atggtgatcg agaaggtgaa gccatcgcgt
     7321 ggtcgattat tcgacaagca aacgcatttt ctaaggaaaa gaactattta cgtttatgga
     7381 tcaattctct tgaaaaagaa gcaatctatg aaggttttaa gaatctccaa cctggaaaga
     7441 actattttcc aaaatataaa gaagcgcaag caaggcagaa cgctgattgg ctgattggaa
     7501 tgaatggaag tccattatat agcttgctac ttcaacgaaa agggattgat ggcagttttt
     7561 ctcttggtcg tgtacaaaca ccgacactct atatgattta tcagctgcaa gaagaaatca
     7621 aacacttcaa aaaagaaacg tactttgaag gagaaggttt aattacgaca aacaaagggc
     7681 agttttctgg aaaaatcgta ccaaaaaaag catttaaaac ccaagaagag ttaacgaagg
     7741 aaatagaaaa acttggagcg catttaggta agcaaaacgg acggattctt gaagttacga
     7801 aaaaggaaaa gaggttgcat agtccacgtt tattttcgct atctagtttg cagacaaaga
     7861 tgaatcagct aatgaaagca agtgccaaag ctacacttga tgctgctcaa ggattgtacg
     7921 aaagcaagtt tctaagctat ccaagaacgg attcctttta cattacagaa aatgagcatc
     7981 agtatctggt taaacatctg caaaattata aaaaattttt aggaatagaa gaagtacaga
     8041 caactgagat caaagcaaag aaacgatatg tcgatgcgaa aaaagttcaa gaacatcatg
     8101 caattattcc gacaaagacg attccgactc ctgcacgctt tgcgaagctt tccaaattac
     8161 agcaagcaat ctatttgcaa gttttgcgca ctactgtggc tatgtttgct gcagattata
     8221 tctacgaaga gacgaccgta atgacgggcg tacagcaatt aaagctaaaa agcatcggaa
     8281 agatcccatt acagcaaggt tggcaggaaa tcttacgcat caagtcaaaa aagaaagaag
     8341 ctcagactct tcctcctatc gtagaaaatg aagaagcaga agtagaactg aaaagtatgg
     8401 agaaagaaac acaacctcca aaaccctata ccgaaggaac gttgatcaca gcaatgaaaa
     8461 ctgcgggaaa aacgctggat aatgatgaag cgcaagaaat tctcaaagaa gtagaaggaa
     8521 tagggacaga agctacacga gccaatatca ttgaaaatct taagcagaag cattacatcg
     8581 aagtcaataa aaacgaaata actgttacgc caaaaggaat cactctttgt aaggcagtag
     8641 ccaatgaacc attactgacg agcgcagaaa tgactgcgcg ctgggaaggg tacttgagaa
     8701 aaattggtaa acaagagggg acaccatctg tttttttaga gaatatcaaa aaattcatcc
     8761 tacatttatt ggcagaagtt cctaatcaaa tcgacaaggt agacttttca gatgagatta
     8821 gcgggacacg tcagataaaa gcgatggaga agaaaaacga tcaattagga agatgtccaa
     8881 aatgtaaaaa gggaatagtc atgctttatc ctaaaatcgc tacatgcttg aatccggaat
     8941 gcgacttcaa attgtggcca acagtagcta aaaagaagct gactaaaacg aatctcagag
     9001 atttgctttc aaaaggaaag acaagtaaag ttgtcaaagg ttttactggt aaaaaaggga
     9061 aattcgatgc agttttagta ttaaaagaag atatgacaat cggtttttct tttccatgga
     9121 tcgaaaacag tggaacaaaa gcagttgatg gaaacaaaga aacatcaaga aaaaataatg
     9181 aaaacgaagt agagtaaatg aaaacaatga aatagcggaa tatttattcc gaaaagtgag
     9241 aatataaata ccaataaaac taaaaaatat cagtgaatca agcaaaaacg ttggggtagg
     9301 ctgattttat atagatagca aggagttttt ttatttgaaa aaagtgcatt catttttaaa
     9361 ttatcttatg ggagcaatca cgattgtggc tgtgtaccaa gcatttctaa agtatcctga
     9421 ttacgggacg aagttgttgt cattgacgca caatcaaaca gcatattcac caacgttgat
     9481 tttatcgact ttgactgcag gagctaaaag cgctacttat ttttttcata aaacgacaag
     9541 catgctaaag cgaaagaaac agcgaaaaca attgttggtg gtggtagcgg ctatgatcat
     9601 tatttatttt ctaccagtta ttacacaagt atttcatcaa tattttggtt aagaatacga
     9661 gagtttgtga caaaagtcat gtcacaaact tttttctttg tcattttttc gtaagaaaaa
     9721 gcaaaataaa agtatataca ttgattaaaa gtatatactt ggatataatg tacttactat
     9781 agaatgagaa tggtatagag ggtggcgaaa tatgaaaaaa atgaaaaagt ataaaattag
     9841 aaaatctggc aatagcgatg taacaactat cccaccagaa gtaaaagaat tcatgggtgt
     9901 gcagacaggt gacgcaatca gttatgtttt tcaatctgat ggttctgtac gaatgatcaa
     9961 agcacaagaa gaacctgata ttgattcatt agttgattcg atcatgaatc aatatgaaga
    10021 cgcgttaaaa gatttggttg atttatgagg tatctttcga ctaaagaaat tatcaaaatc
    10081 aacgcgaaag ttattttacg tcactcgcca ggcgaaatga tcggtgtaaa agatgcaaat
    10141 gcattagata tggccgtcaa acagccttca caagcagtat tcaatcaaga actctatcct
    10201 gaaatctatg aaaaagcggc gattttagca attaatttag ctaaaaaaca tccttttcat
    10261 aatggcaata aacgaactgc tcttgttgcc atgttgttgt ttcttcaatt gaataattgt
    10321 ccagttgctt tttctcgtca agaagctgtt gattttatca taatgattac cactagttca
    10381 ttggatttcg attcactaaa gtccaagata accagttatt tacgacaaac cgcaataaaa
    10441 tgaacgaatt aaaaacttta tttctcaat
//
LOCUS       DADGHT010000098        10419 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.099, whole genome shotgun sequence.
ACCESSION   DADGHT010000098 DADGHT010000000
VERSION     DADGHT010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.099"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..206)
                     /locus_tag="JX887_002342"
     CDS             complement(<1..206)
                     /locus_tag="JX887_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258285.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQV"
     gene            complement(196..534)
                     /locus_tag="JX887_002343"
     CDS             complement(196..534)
                     /locus_tag="JX887_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258286.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(524..850)
                     /locus_tag="JX887_002344"
     CDS             complement(524..850)
                     /locus_tag="JX887_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAX1258287.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(831..1109)
                     /locus_tag="JX887_002345"
     CDS             complement(831..1109)
                     /locus_tag="JX887_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAX1258288.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(1111..2475)
                     /locus_tag="JX887_002346"
     CDS             complement(1111..2475)
                     /locus_tag="JX887_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAX1258289.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(2488..3063)
                     /locus_tag="JX887_002347"
     CDS             complement(2488..3063)
                     /locus_tag="JX887_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HAX1258290.1"
                     /translation="MEMKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWD
                     DLSEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDT
                     TVARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYED
                     TEAALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(3029..4216)
                     /locus_tag="JX887_002348"
     CDS             complement(3029..4216)
                     /locus_tag="JX887_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAX1258291.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(4280..6007)
                     /locus_tag="JX887_002349"
     CDS             complement(4280..6007)
                     /locus_tag="JX887_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAX1258292.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(6004..6456)
                     /locus_tag="JX887_002350"
     CDS             complement(6004..6456)
                     /locus_tag="JX887_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HAX1258293.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(6568..6948)
                     /locus_tag="JX887_002351"
     CDS             complement(6568..6948)
                     /locus_tag="JX887_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAX1258294.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(6945..7331)
                     /locus_tag="JX887_002352"
     CDS             complement(6945..7331)
                     /locus_tag="JX887_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258295.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(7333..7611)
                     /locus_tag="JX887_002353"
     CDS             complement(7333..7611)
                     /locus_tag="JX887_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258296.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            7659..8387
                     /locus_tag="JX887_002354"
     CDS             7659..8387
                     /locus_tag="JX887_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HAX1258297.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(8533..9009)
                     /locus_tag="JX887_002355"
     CDS             complement(8533..9009)
                     /locus_tag="JX887_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HAX1258298.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(8969..9316)
                     /locus_tag="JX887_002356"
     CDS             complement(8969..9316)
                     /locus_tag="JX887_002356"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258299.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            complement(9303..9488)
                     /locus_tag="JX887_002357"
     CDS             complement(9303..9488)
                     /locus_tag="JX887_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258300.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(9489..9761)
                     /locus_tag="JX887_002358"
     CDS             complement(9489..9761)
                     /locus_tag="JX887_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HAX1258301.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(9758..9961)
                     /locus_tag="JX887_002359"
     CDS             complement(9758..9961)
                     /locus_tag="JX887_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258302.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            10086..10298
                     /locus_tag="JX887_002360"
     CDS             10086..10298
                     /locus_tag="JX887_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258303.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
BASE COUNT         2969 a         2106 c         1598 g         3746 t
ORIGIN      
        1 acttgatcgt tttcaactac tacttttatt tgatcgcgca tatgtttctt ttttaagagc
       61 gacttaggaa tattaggaag caactgcttt agataaaagt tagctgcttc ttctaaagat
      121 tccaacgata attttttcgg atcaactttt gaaaggtttc ctaaataatc cgatatttca
      181 gaaaaaccat tcttattact tggcattttc cacacacctc acatatgtgt aatagttggt
      241 tacggtatcg tcgttctcat caccttgtat acctgtaaaa tctgaatatg gaatgccagc
      301 attttgcagc gcttgttcaa taacaactaa atcctgttct gttccaagtg taaaaaaaga
      361 gacttggtaa taaggtaatt ttttatagac tttaccggat gccatttttt tgctgttact
      421 cacatttgag tacacaatgt atggatacat cgtccctaat ctggctttgt ctctgaacac
      481 tgctaacttt gttgatttca gcgctgtttt caattcatca aagctaatcg acataagcta
      541 aactcaactc catttctctt gcatcgggat tcgtataaat gcgagtaatg ttatacgtta
      601 cagaatcaat tttgagcgca cttaatttct ctgtgatgga tttatcccat ctgactttaa
      661 ttcgtctgac aacgtctgtc ttggcttgct gtgataaata tttttcttga gaagtcacac
      721 cgagttcttc atagaatatt agacgcttaa attcgtaaat tgtagttgga cgatcgtttc
      781 cgtctgttcc tgttttgatg tctagcaatt cggctttcca tctgagatta ttagtctgtc
      841 tcttcggcat tttgaatcgc tccttgcacg ataaatggcg tcatggcatt catagctttg
      901 tcgagttcat cctctgaaac tctatattca taggcaatgc cggcaaccat caaaataaga
      961 tattcttgtt ggccaccagt tgctgttttg acataatctt ttgccatatt taaataaaaa
     1021 gagagcaaag aatcatccat gccctcttca aaatgaatat gtgatttgaa tttttcctct
     1081 aaagacaatt ctttagtttg ctcttccatc ttaaccacca actggttttg taatttcgta
     1141 gcgatatact gccggttcaa atggagaata aaccaattga ccatctagca agttgtaaat
     1201 ttggaatcca atttgatttt taccagagaa tttttcaaca agtttttgaa tttccaaggc
     1261 accaataact tcttgaattt taaatgcaga aaaatcgcca aaatataaaa ctggcgtgtc
     1321 tggttcaccc tttttatctg ctgcatctgt ccaatccaca ggatagccaa ctaattggta
     1381 accaattcca ccttctgctt gtgtgaatgg ccgcaacaaa ggaaatccat catctgtttt
     1441 cattttttca atggcagtca aagcagctcg attaataata aagcgtccct ttttcatcac
     1501 ttctgtcact ggtgtatttt taaattcgat taatgcatca tataattttt gcccagcacc
     1561 tgaagcagtt agatctaaag gttttttaaa tgctacagcc tttttggcta atgcaccagg
     1621 attttcattt ccagcgtcat caccattgaa catataattg atttctttac gcacataagc
     1681 ttttttcaat tcttccacaa caatatcttc aactggaaca ccagacattt ttaataattt
     1741 tttagttact gttgccaaag catcgaattc ggcaggatta agcaaaattt catcaaactg
     1801 aatagctgtt tcagcaatat cagttgaacg ctctttcttg tttacattcg catctgcttt
     1861 cttcacaaga attggatatt tgacatctcc tgatgttcgc accactgttc cgtatttacg
     1921 aagtaaattt tcttcttgag cataagtaat aacttcagat gcaattactt ctgggacagt
     1981 aactgaaccg ttgccagctt caatccctaa agctcgagct tctgcttcag aaatatttcc
     2041 agctacaaaa ttagcaaatg cttttcgtag ttgttgatct ttttgtttct tggtcatttt
     2101 tgcacgtgcc tccaatccgt tcttaattga tccaagtaat ccatctcgtt gctgttgagt
     2161 aatcattcca gaacgatttt ctgaactatc ttcactgtct gaatcttctt cttgatcgtt
     2221 gtcttcacca gaacggcttt cgtctgaatc cgtactattc gattgatcat ctgtattgtc
     2281 gtctgtttca tcagttccag aatctgcgcc taattcgtct ttaattccgt tcaattcatc
     2341 aataacactg tcaatttctt ctttcacggc ttctaaatct gcttcgcgta attctcctga
     2401 ttcaactttt tcacgtaatt cagtcaatcg ttgctcacga cgtgccttca tttttttcaa
     2461 taattcttta tccatgtatt tttcctccta cgcttctagc gcttgattaa tttttttgat
     2521 taattttttt ctttcttcga cgtttttttc taattcatca cgacttctta atgcagcttc
     2581 tgtatcttcg tatgctggca aaggcacaat agaaacctcg tataattcca cttcatggat
     2641 tgttcgaagc attggttcag aattgtagtc ccacgtttct tcagtcggca caaaaccaaa
     2701 actacattgg ttgatgtctc ctcgttccat agatttaact aagtcccttg ctaccgttgt
     2761 gtccggtaaa tcaacttcga atttcaaacc acgttcatct tcttcaaggc gaagggttcc
     2821 gcttttagta cgtcctagca cattggacca atcgtgattg aacaaacaac gaacatccga
     2881 attactaatt gcctttgaga atgcaccagg aacaatcact tcgcttaagt catcccataa
     2941 aagtgtttga ctgttgaata cagcagcgta gccgctaatg gtcctcgtat gagtttcttc
     3001 atcggaacgt gttgaaagat tggtgatgtc aatcgtgcga atttccttct tcttcatttc
     3061 catcacctcc tttcaagtct tgatcattcg ttggtaagga atcatctgtt gcatttttct
     3121 ggccaatcct agataagtca tttgaaatat agatagcttg tgtttctgga gtattctgtt
     3181 taggaaaacc aagcatttct gccacgttat ctggacttgt aatcccggta cgaacgatgt
     3241 tgtagccaat atttgttttt gttgagtaag gaacaaaatc caaaatatta attttccatt
     3301 ccactctata gccagaatta ggcataaaaa aaagagcggt gtaatgttcg ctcttgtttt
     3361 tcaatattgg tttgattgct ttgttgtgca gatacatcat cgctttttca atatctgtct
     3421 tcatcagcga ttgatacgta tcaacattga ttcctagaaa ttttcctaag tcttttttgt
     3481 aaacacctaa ataattcaaa attgccgcgt catcaacagg actttttaat gtctcgatgg
     3541 aatatccttt tcccaaagga atcatcttaa cagaatgatc actctcattt tgcgttcctt
     3601 ccagttgatc caatatagct ttgacaattt ttgtttgggc gctattattt ggattgatgt
     3661 gggcgtctag tttaagcatg aacgcaagta aaccgccttt agtatatttg tccgtcaaaa
     3721 ctttttcagc gctcagaacg ccttctagag tgtttcttgc aagatcaatt attccagcac
     3781 cttttaatga atcagttccg atgttcttaa tgtgtcgaat catttgacca ggtatttttt
     3841 gaccattcat ttcaaattct tcttgaagtc gttcattgat tttagttgtt acaccgtacg
     3901 ccaaatgaag ctgatcccta tccgttaatg ggaatgtctc accattgatc aataaagtat
     3961 ttgtttccaa tttggtaaat tcgaatcctg tcaaataatc attgggactc ttcaaaatat
     4021 ttagtaagtg atgatctttg acttcgttgc cgtcgggacc aataacaatt ggtgtggcca
     4081 atgccacctg attagatatg tcttgaacta attcataaac atcagaagat tccatgatag
     4141 atgaatccgt cacatatctt tgaccataac gtgtgtagtg tccaaaaata tcctcgatat
     4201 atccacgttt ttccataaaa gaatagactg cattcgataa ccgatcacgt aatttcaatt
     4261 tttttcaccg cctttctatt tatctataga tggaacttag gtaatcatct aactcatctg
     4321 aatcaatatc tgtcatttga ttcatcgttt ccttatgacc acacaaaaac gccacgaacc
     4381 catcaatctt tttctttgat tgacgtttac ttggcgcttt ttgtccattg atgttagtaa
     4441 ttgctacaac gttcaaagtg caataaagga ataatggatt atcaaattga attcgtttct
     4501 cataaaacaa ccgttcgaca tcgtcaaaag gagcattcaa tactttagga tattgagcaa
     4561 cttcaacgca ttccaatcct aagttttcta atttctcaac aagtttgtca ctcatcgctg
     4621 gatcataatt cacttgctga atatcatata aattcatgca gtcctctatg tactgcaaaa
     4681 tctgatcttg atcaatcatt tttccgtcgc aaaattcaac gaaaccttgt tcagccaaat
     4741 cactgtaagg aacattatct tctttttctc gaaactctaa atcttcattc ggaataaaat
     4801 aaagttgctt tactttaaga accgctttac catcttcatc ccatgttggg aagtttaaag
     4861 atacacaggt caaatctcgt gtacgtgata aatctaaacc gatataacat ggttcgccac
     4921 ttaaatcacc aagttcttgt gtggtaacta aacatggctc tacttgatcc tgttcaaaga
     4981 aattatccgc gccgttcaca aatacatcca agtgtttcgt tagaaattca gctttggaat
     5041 gagctgaccg ttgcgctgtt ttaaatgccg attctaaagc agataaatcg actgatattc
     5101 cccagttagg attgcacatt tcccagactt ttctatccgt ccaatcataa tttttatttg
     5161 gctcatagat tagaacaaag tttgaatcat tatcatcacg tttcaacact tcttttgctt
     5221 cgcgatatac acgcattcca acagacgacg aacctttccc agcagttgag atattaaaca
     5281 tcaatggctg tggtaaagat atctgagcag acttaaaatt gtcatactgt tccattttct
     5341 cctgtttatg caattcatcg ttcaatacaa aatatggatt ggatccctcg atattatcaa
     5401 tattcttggt ttgaacaata aatttatttg agtaagccat atcttcatga atatagtcat
     5461 aagtaatact agaaacagtt ccctttggcc ccctaaatat tttagttcct tcaagtagga
     5521 ttggattgtt taagattgta actgcaaaag gtttggcagc atattgcgct tgagcaaaat
     5581 cagatgcgca agcatagcaa tcaactgata acgccccttc tccgtacatt gcatatccta
     5641 atgaaccgac agcaatcaat gttttaccat tcttttttgg aatctggaca taagcctcac
     5701 gagtaacgcg tacaatttgg cctttttcat tttctttaac ccaaccataa atccaagaat
     5761 aaataaattt ttcccagggt tctaaaagaa acggttttcc caccatttct ccttttgtgt
     5821 gaacaataaa tgattctacc caatccatca tttcattcgc gcgatctaca tcaaaccaaa
     5881 tatcttttct ttttttccac tgataccagc gatctattgc taaacgaacg gtcttaggat
     5941 acttcttagg tttctttctt acttcttttg caaataaatc agcataattt acaccaggtt
     6001 caatcatttt tcagcacctg ccttcttacg ccatttattt ctgtgcgctg ctagttcatc
     6061 tactggcttt acttctgggc gtgtaatttc ttcatctttt cttgcggtcg atcctccagc
     6121 aattagtcta ccagtttttg ctttgtttgt taatcctaat aaatctagag ctttcatctt
     6181 cttatctgcc caagtttcta cttgttgtgc caatggatgt tttgattgat tagtagctcc
     6241 tgatttattc gtgaattttt gcgtctccgg aaatcctttt tccttccaca ataaatattt
     6301 gtgttggtaa atttcaaaaa tatccaagta tgattcgatt aatggatcaa gagtgatggt
     6361 gtacaaatca gacaaattca ttatttctaa gatacgagct ttttcagcac ttactttttc
     6421 atcaataatc gctttacgtt gcgctttagt cgtcattttt gtatacaccc ccctttgttt
     6481 tttgaaaaat ttgacctaac gatgcgcgtg actccccgct accctatctc cccacgcgaa
     6541 aaaattttga aaatgaatag gggggcttca attgaaatac gaaggaaaaa cttttttgtc
     6601 ttccgtttcg ttttcaacaa ttggatgaca ttttgaacat aatagcatga gattgtttgg
     6661 atcaagctta agcagttcgt tgtctttgat tggtacaatg tgatggacgt gtgctctctt
     6721 tccaaatatg aactgaccac accgctgaca atgaccacct tctctttcat aaataaattg
     6781 acgcatatct ttccatgctt gcgttcgata gaatggtttg ttctcatgat gataaacaga
     6841 ctttgcttgc tgcttcttct tgcgtgatct gcttgatctc ttgtgttcag tacagtagat
     6901 accctttgct attttgttcg tgcatccgtc aaactgacag tatttcattc tacttcacga
     6961 ataagattta tgatatcgcc ttttgcacgg atagcaccag gaatatcaat accatgtttc
     7021 ttagcatatg cacgcaattc ttttgcagtc atattgtcca gttcatccgt atcttcagtg
     7081 gactgatcat tagtagcttc gtctccatca aaattagcag cagtgtttcc atcgctatca
     7141 agaatttcac tgctatgagc tatgagttcg ccattgacag caacaaatga tttgccatca
     7201 ctcaaaattc ctttttcttc ttttacttca aaatttggtt cttgatcttt cggaacaact
     7261 actgtccttt tcttttctga atcccaatac tctgttccac taatggatgt tctaattttg
     7321 atcattgcca ttttaattct ctcctttgta atttgtacgg attacttttg cgcccattcg
     7381 ctcataccat tcaatcgttt cctgcagatt gggtagagtg tgtgacaata aagaaataac
     7441 taacgtattc attccagttc tgtaatcatc attctccact tgcacatgtg catgattacc
     7501 attccaattt tctctgtacg gactattctc tgcttcaatt gctttcttat aaactttagc
     7561 caaacttgat tctacttcaa tactaagtac cgcttcatga aaatcattca tttgtttact
     7621 ctcctatcag atattttgtg gtatgattta taaaaaagat gcgaggtgtt ttaatgcttc
     7681 aagaagttaa tattaagtat cgtgatcgtc aaaatacaga gacaatttat ttgccaaata
     7741 gttgtccgca ttgcggaaat ataatgactc cgtatgtgta ttttggggtt tcatcatata
     7801 gtgcgttcga taatgataga atctttggcg tattagtaca gtgtataaat gatgagtgca
     7861 acaaatttta tagtttacaa tttataaata cgtttaatga agatgaagga tattctgaaa
     7921 atattttaat taaagattat taccgtccgc cgattaaaat agatttacca gaaaatattg
     7981 aaaaagtttc tcctacattt gttgatattt atactcaagc cacacaagct aaatctgagc
     8041 aattggaaca aattgctgga gttggttata gaaaagctct agaatttcta attaaagatt
     8101 atgcaatatc taaaaattca gaggatgaag ataaaataaa aaaaatgtta ttaggtaaaa
     8161 caattgaaaa ttatttgaat gattttccta aactccaaag attagccaaa gctgctactt
     8221 ggattggtaa tgatgaaacg cactatgttc gtagacatac taataaagat gttcatgata
     8281 tggatgcatt tattaaatca gcagcgcaat ttatcgcggc tgattatgat gctgatttag
     8341 ctgatcaatt tataaatgga aataacttta tgccaactac taattaaaag aataaaagag
     8401 ccacagatac caattaataa aacggttggg atatcttggc tctttcatat ttttttgaca
     8461 ctaatagaat atcatgctgc taacaatgtt tacatagcta caatgaccga acatttagtg
     8521 aacagtgtaa ttttagaata aagagagttg ttctttgtac ttctcgctat tgtaaaaatc
     8581 aatttcgttt tcttttttca atcggtcagc ttgtctgtgt tcatactcat ctaaaaagtt
     8641 caatgtcttt ctaatttctg catgtcgctg tctgacatac gatgagctat acccaacaga
     8701 ttcagcaata tcttctaagc tcatttgatc aacatatttc atcttaacaa tttgattatc
     8761 gataccagaa aagctatcta tcagcaataa catttcttct ttttgctcga tcaacaattc
     8821 caattcattt tctatctttt ggatattctc ttctaaagaa gaagttctcg aattcttttc
     8881 gatgcggacg tttgctaaat caccacagac ccatcgattc aattcaagct tacttttatt
     8941 aagattccac tttaagtaaa gaatctgctc atctagttct tggtaatctt ttaaccaatg
     9001 aaatctcaca aacgccaccc cttatggtag aatagtattg cgctgctatc tcgaaagggg
     9061 tagctttttt attttttctt agccgttcca ttctggattg ccttttgttc caaacgtcgt
     9121 tttttcttct taatctttga ttttgttttt cccatacaat tctcctttcc gaaaacacat
     9181 tttgttcgat ttttaatact aaataaaagt tggccagaat ttttcgttcg tctttactca
     9241 tctttttttg aataagatta ctagcataaa aatagttagt accacgaaaa tgaacaggta
     9301 aatcaattac gttcaccttc ttcatgccag ttatcagcca ctagaatctt tgcgttagtg
     9361 ccgccaccgt tttctttttt gtatttttca aatgctttat aagcagctgt ttttgattta
     9421 tagatttttc cggaaccgac tgggaacatc catgtgccct ctgtgatagc taagatgtat
     9481 actttcattt aattcacccc tttaatcccc aacactacat atccggactt ctgcatgtaa
     9541 tcagtaatat aagtgatctc tgctttgtat gagtcaccag tgtaactaaa tgttggtctc
     9601 gttagtccag gtaattcatg tttaatgtat tttttatatt cacgtagtat taactgatca
     9661 ccaactttga agtcacgatc attcttgcgg atctcgaatt gtttgcgtcc gctcgtcact
     9721 gcttcaaaat attctggtag tatttttagt tcgtggatca ttctgtttcc tccttcaaaa
     9781 ttcgctcatc atcaaaaagt gaatctccac aaaatccttc tcccaaatat ttatcgttca
     9841 tgtataagtc aaccaaatat ttgtgatctg cttctcgata ttcattaata ttaacgatct
     9901 ttattttgta aacattacct tcgtcgctca ctatcttgaa ttgttctctg actttcacca
     9961 ccgttcctcc tctttttgaa aaaattttag tgtttttgta agacccccta aatcagcttt
    10021 tttatttgat ataatacttg tatcgattaa tcaaatcgaa attaaattta aaaaggtgat
    10081 ttatcatgaa tatcaacaat ttagtaaaac tcgttgaaca acgttttaaa gaatcaggat
    10141 tagaacaatt aaaaaaagat aattctccag aattattttc taattttacc gaagacgaca
    10201 ttcctactct taaacaatta aaatattatt ctgattattg gacgcaaact cgtgagaatg
    10261 aattaaattt agaaaaactc attattaaaa agaaatagca actccagccc acacggctgg
    10321 ttttttagtt tcaacttccc tccttacggg tcaaaatcat cggttccggc ataatctgat
    10381 catcctttag caacaaatca ggatattttt tccttagct
//
LOCUS       DADGHT010000099        10318 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.100, whole genome shotgun sequence.
ACCESSION   DADGHT010000099 DADGHT010000000
VERSION     DADGHT010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.100"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(71..904)
                     /locus_tag="JX887_002361"
     CDS             complement(71..904)
                     /locus_tag="JX887_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAX1258304.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(1208..3373)
                     /locus_tag="JX887_002362"
     CDS             complement(1208..3373)
                     /locus_tag="JX887_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1258305.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            3633..5927
                     /locus_tag="JX887_002363"
     CDS             3633..5927
                     /locus_tag="JX887_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAX1258306.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5920..6585
                     /gene="pgmB"
                     /locus_tag="JX887_002364"
     CDS             5920..6585
                     /gene="pgmB"
                     /locus_tag="JX887_002364"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAX1258307.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            6578..7585
                     /locus_tag="JX887_002365"
     CDS             6578..7585
                     /locus_tag="JX887_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAX1258308.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            7607..8626
                     /locus_tag="JX887_002366"
     CDS             7607..8626
                     /locus_tag="JX887_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1258309.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(8907..10274)
                     /gene="nhaC"
                     /locus_tag="JX887_002367"
     CDS             complement(8907..10274)
                     /gene="nhaC"
                     /locus_tag="JX887_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAX1258310.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
BASE COUNT         3198 a         2242 c         1909 g         2969 t
ORIGIN      
        1 ctctccaaac ggtataatcg tttggagagt tttattttaa tcagtttttt tatgttatat
       61 gttatatttt ttattcgttc acatctaatt cgatttccac cccgtagtga tcactgatga
      121 ttggactatc gatcccatca aaaatccgtt gatatttttt aacctgcatt ccttcaggga
      181 cgaaaataaa atctatacgc aatttttctg tattttgttc ccaaccatct attttctttt
      241 ccacagtagc tgcttttcct ttttcattcg cgacaacata cgaatcttga agaagaaggc
      301 aactttctct tacagtataa taaccttgag agtctactgg attattgaaa tcacctagga
      361 aaaaaagtgg tacgcgagtt tccaaaaagt agttttccaa gtttttccac tcaaaataaa
      421 agccactttt tttatctgtc caccaagaaa agtggcagct cgagacaaaa atgtcctgat
      481 catctatctt tgttttccca atcaagatct tgcgtgtctg ataatcttct ttcttttgaa
      541 attgggagac ggtaaggacc tgactttcca atgttttttt cgtaagcagt gcatttcctt
      601 cttcatattt atcataaccg atgtggctca tttcccaact ccaaaaatac tcttttccgt
      661 gttcctttaa aagctgaact aaacggtagg caaaattatc tttacggata ggtacttgat
      721 tctttaccgg acagaacttc attagcttcg caggttctac ttcttcagat tccagtaatt
      781 ggttgatttc ttgtaaagca atcacttcat aatcttctaa caggatctta tctgctaatt
      841 cttgcaattt tttctctggt tctggctcaa gccagctatg cgtgttgagt gtcatgaatt
      901 tcattggttt tctccttgtc ttcatttcga aacaaaaggg ttgtgacaaa atttttgtca
      961 caacctctcc agcaaatagt gttctcctgc taactcctca gtaataagct caatggacca
     1021 ggagctattt tttgtttggc tgtttttatc acttggtgca gggcagcttt ttcacgacct
     1081 ctccactaaa cagtattcaa actgctgctt ctcggtaata agcccaacca aacgaaaaat
     1141 aggaggagct atttttgttt ggctgttctt atgacttgat gcaggacagc tttttcacaa
     1201 cctctcctta cattttaatg gagccgatca ctttaccagc tgtcactgta cctaattgct
     1261 tgatcactac ttcttctact ttatcgtttg taaatacgat catgatcgtt ggatcttttt
     1321 cttcgttttg gatcacatca agatccatct cagctaattt cgttcctgtt cctacttctt
     1381 ggccttcttt gacagcaatc tcaaaagctg gctgattcat ttggactgta tcgattccca
     1441 tatggatcaa aacttcgata ccatctttcg tttccagccc aattgcatgt ttgctaggga
     1501 aaatacttgt cacttttcca gcgatcggcg caacaacttc tcttgatgtt ggaataacag
     1561 caaagccgtc acccatcatt ttttgtgaga ataccggatc ttttacttca gataaaggaa
     1621 tcacttctcc agaagctgcg gaaactagtt cttgttctat acctaagtat tgcttactac
     1681 ctgcttgtcc atttcctgta gaaaccattt ctggctctgg aatctctgct cctgattgca
     1741 gcagatcttc gatatctgat ttcaagacat ctgcttttgg tccataaact gcttggactc
     1801 cattgtcttt gacgatcaat cccatcgccc ctgctcgttt ccaggcttct tcagtcccta
     1861 ctttttctcg atcatttaca cttacgcgta accgagtcat acaagcatcg acatctttga
     1921 tattttcttt tcctcccagc aaatgaatga tctggaccac ttgctgatct gctgttcctg
     1981 ttccgctgtt agatacaacg gtttcttcac tgtcattgtc gtaatttccg ttacgtcccg
     2041 gtgtagcaaa gttgaatttt ttgatcaaga aatttgctaa gaaatacgta acaacaccaa
     2101 aagcgatcac acacaacacg aagttgataa gatctccacc tagacccgct ttgatagcta
     2161 acggtgtccg agtcagcaat tcgatattcc caaatgaatg gacccgcaat ggcaagatat
     2221 ctgccatcgc aaatgcagcc ccttggatca ctgaataaat gacatataat ggcacagcag
     2281 caaacataaa catgaactcc aatggttctg ttacacctgt tagaaagaca gccaacgctg
     2341 ctgaaaaata cattgattta tatcttgctt tcttatcagg atcgacatta cgatacatcg
     2401 caaaagccat tcccatcaag atacctgaag aaccaatcat ttgtcctact ttgaaacgag
     2461 ccggcgtcca gttatgcaac acaaactcat attgcgacat atcccctgca cctttaagat
     2521 tcactaaatc agtggcccaa gccaaccata acggatcttg cccaaatact tgtgtccccg
     2581 cctgtgcgcc tgataaaatc tcatacgatc cgccaagctg tgtatagttg ataggaatcg
     2641 tcagcatatg atgcaatcca aatggcaata gtaaacgttc taatgttcca aataaaaacg
     2701 gtgctagaat cggtgcgctt tcttgtgatt ctgcaatcca taaaccaaaa ttattgattc
     2761 cagcctgtac gtttggccac accacagcaa gaatcaatgc cacgattgtt gaccataaga
     2821 taacaacaaa cggaacaaag cgctttccat tgaaaaatga caaagcatcc ggcaattttc
     2881 tataattata gtacttatta taagccattg ccccgacaaa tccagcgatg atccctacga
     2941 atactcccat attcaaagct ggtgcttcca atacacttgt aaaaaatcct ttaaccatga
     3001 tcttcgtacc gaacagagtg tgggtaaatg catcttcatt cgcaagcatg tcacttgtga
     3061 caccaaagat agccccagtg atccgattga ttaaaataaa tgagatccca gctgcaaatg
     3121 ctccgcctgc tctttctttt gcccaacttc ctcctattgc taaagcaaat aaaatatgaa
     3181 gattaccaat aattgcccaa ccaatatttt caattactcc gcccgttgtg acaagcggcg
     3241 tccaatcagg attgatcaag ggaattgatt tccctatact gatcatcaac ccagctgccg
     3301 gcataactgc taccacaacc attaaagcct ttccaaattt ttgccaaaac tcaaaactaa
     3361 atatcttttt cattccgttt agctccttta cgcaatcggt ttcgttaaac gtattatagc
     3421 gtgcgttttc ttttttgtaa atgctttatt ttttattttt ctgtctatac cattctataa
     3481 aacctataat acgtgtgttc ccttctataa ttttctccta aaaatttatt tttttaagct
     3541 tttttctatg aaatattttc ttttgtctat tgacttgtgc aatcggttgc gtttattatg
     3601 aacgtataaa acagctcatt aggaggagaa aaatgaaaca gatcaaacga ctatttgcta
     3661 ttgatccatg gaaaatcagc acgacacaat tagataaaaa aaatcttcga ctgcaagaat
     3721 ctttaacaag tattggaaac ggttatatgg ggatgcgcgg gaactttgaa gaaacttact
     3781 caggggacca ccatcaaggt acttatttgg cgggtgtctg gtatcccgat aagacacgtg
     3841 tcggctggtg gaaaaatggt tatccagaat actttggaaa agtgatcaac gccttgaact
     3901 ttatcgcgat agatatttcg atcaacgatc agctgatcga cttggcttct ttggaaccag
     3961 aagactttta ctgggaatta gatatgaaaa atggtgtatt atctcgtaca ttcacaatca
     4021 ctacttctac taataaagta cgcatttcct tcgaacgttt tctgagcatt gtcaaaaaag
     4081 aatcagctta tatctattta actatagaaa tgcttgaagg tagcggaaca gtcaaactcg
     4141 tatcaaaatt ggatggaaat gttcaaaacg aagacagcaa ctatgatgaa catttttgga
     4201 atgagattga tcgtggaact atagaagaaa tcggctattt gacgactaaa actattccaa
     4261 acaactttgg gattgaacaa tttactgtta ctgcagcaat gcgccatttc gttaatggaa
     4321 aatcagtcat ccctgactat cacgaagata ctttagcatt acatggttgc ttgtctgcag
     4381 aattatctca aggtgagaca tggtcagtgg aaaaagaaat tatcgttctt actagtagag
     4441 atattccaga agcgcagcaa gcagaaaaag ctgtctcaga attaacgaac cagacaaaca
     4501 attatatcca agcaaaagaa gagcaaacag cggcttgggc agaacgatgg aagcttgccg
     4561 atgtggtcat cgaaggagac gaagaagcac aacaaggtat tcgattcaat ttgttccaac
     4621 tattctctac ttactacggc gaagatgaac gattgaatat cggccccaaa ggattcacag
     4681 gagaaaaata cggcggagcc acttactggg atacagaagc gtatgctgtc cctctttatc
     4741 ttgctttagc caaacctgaa gtaactaaga atctgctgaa atatcggcat aatcaactgc
     4801 cgcaagcaat ccacaacgct cagcaacaag gattaaaagg cgcgctttat cctatggtca
     4861 ccttcactgg tgtcgaatgc cataacgagt gggaaatcac attcgaggag attcaccgaa
     4921 atggcgcgat tgcctatgca atctacaatt atacgaatta caccggcgat acggaatatt
     4981 tgaaaaatga aggactggaa gttttagcag aaatcgcacg cttctgggca gaccgtgtcc
     5041 atttttcaaa acgagcaaat aaatacatga tccacggtgt gaccggccca aacgaatatg
     5101 agaacaatat caataacaat tggtatacaa atacgatcgc agcttgggtc ttgcgttaca
     5161 cgcgagaaaa ttatttaact tatcaaaaag aagctgctat cactatcagc gaagaagaac
     5221 tagccaaatg gaaagatatc gcagagaaca tgtacttccc agttgacgaa gaattaggaa
     5281 tctttgtcca gcatgacaca ttcttagata aagatctcat gcctgtatcc gatattccca
     5341 caagcgatct tcctctgaat cagcattggt cttgggacaa aatccttaga tcttgcttca
     5401 tcaagcaggc agatgtacta caggggattt atttcttcaa tgatactttt acaaaagaag
     5461 aaaagcaaaa aaactttgat ttctatgaac caatgactgt ccatgagtct tccctttcgc
     5521 caagtatcca ttcgatttta gcagcagaat taggaatgga aagcaaagct gtagaaatgt
     5581 accagcgaac agctcgcttg gatttggata attacaataa cgacacagaa gacggcttgc
     5641 acatcacttc catgactggt agctggttgt cgattgtcca aggatttgct caaatgaaaa
     5701 ctgcccatga tcagttgaga ttcgcaccat ttctgccaaa aacttggaaa gcttattctt
     5761 tccatatcaa ttatcgcgga cgtttattgt tcatctcagt cacagatgaa caagttactt
     5821 tcgagttatt agaaggttct cctctagaaa tttacgtcta tgaacagtct tattctttag
     5881 cggatcgtct agaaataacg ctaagaaagg aggaagcaaa tgtttaaagg ggtattgttt
     5941 gatttagacg gtgtcattac cgatactgct gaattccatt atcgtgcttg gcgaaagctt
     6001 ggtcaggaaa tcggcattac gatcgaccac acattcaacg aacagctaaa aggcgtcagc
     6061 cgagaagact cactctcttt gcttttagct tatggcggaa aagaacactc tttttcaaag
     6121 gaagaatttg cagaattagc gaaaagaaaa aacgattatt atttagagat gatccagacg
     6181 atcgaaccaa aagatgtctt ccccggggtc gtgcctttac tggattcttt aaaagaagaa
     6241 aaaatcaaga ttgctcttgc ttctgcaagt aaaaacgggc cattcctact tgaaaaaatg
     6301 ggtcttacac cttactttga tgctattgcc gacccggcag aagcaacaaa cggaaaacct
     6361 gcgccagata tcttcctcct tgcagcaaaa gctgtcggac taaaagcaga agaatgtatc
     6421 gggatcgaag acgcgcaagc cggtatccaa gccatcctct caagtggcgc tcaaccaatt
     6481 ggcgtgggac gtgctgaaga ccttggagag gagatcccgc ttgtccctga tacgactttt
     6541 cttacgatcg attacttgaa agaaaagtgg catgaccatg gataatccag agatctccgt
     6601 cgtaccagtt ccagagactg aaataaagaa aatcacattg aagaacgact acttagaagt
     6661 cgttcttctc aattacggtg cccgcctgca ccaaatcttc gcaccagaca aagaaggaaa
     6721 atcagaaaat gttttattgt cttacgatcg tttcgaagat gttctaacag acaaaagctt
     6781 ttttggagca actgtcggac ctgtagccgg aaggatccgg gatgcttctt ggggtgagca
     6841 tagattggag aaaaactgcg gatcacacca tatccacggt ggcacgaaag gctggtcttt
     6901 ccaattttgg gaagtagaag ttttcaaaac tccatcatca ataggtgtgg tcttttactt
     6961 aaaagatgaa ttttctacct atccaggacc aatcactgct acgatcactt accgtttaac
     7021 aaaaaacgaa ttagagatga caacctctgc tagtagcctt gttgaaacca tctgcaatcc
     7081 gaccaaccat gcctacttca acctttcagg aaatggaaca agagacatct atgaacatca
     7141 gttaacggtc tttttagatg gtgtgcttga attagatcaa gaaaaactgc ctactggaaa
     7201 ttggacaaaa aaagaaaaac tgccaatcga ctttagaaaa tccccaacac tgcaagagat
     7261 ccttgcatgt tatccagatg gactagatga tgtatttctt ttgcatcatc ctaggctttc
     7321 caaaacttcc ttacaattat tcgagaagca ttctggtcgc caaatgacta tagcaacttc
     7381 taataaaagt atggtattat tttctacgac tggattcgaa gctgatttct ctgtcaatgg
     7441 aaaacagatg cattcaaact acggattagc aatcgaaccg caagaaatcc ctgatatcgt
     7501 tcatttcccc aaatttggat cgatcaacct ccatcctggt caagaacgga tcagtcagac
     7561 gatttatcgg ttctctgcac aataacaaga gaaaggtgtt tttatcatgg ctattaccgt
     7621 aaaagatgtg gcgaaaaaag ccggtgttgc cacctcgacc gtctctcgtg tcatcaacga
     7681 tcatcctagt atttccgaga caacaaagaa gaaagtccga aaaattatgg atgaactagg
     7741 ttatgttcct aacatgactg cccgcaatct aggaaaacgc atttccagtg ccatcggcgt
     7801 aatcttaccc cctcttgatt caaaagagcg gatcggtaac ccattttatc ttgagatcat
     7861 ggaagcaatc aacgaagaag cgcggaatta tgatatgact acagcaatcg ctactgctaa
     7921 aaattttgaa ttgctgttag agaacgtcca gcgtatgcat ttacaaaaac aagtagatgg
     7981 ttttattcta gtgtattcag atagtcaaga tactgtcatt gattatttat accaaaacca
     8041 catccctttc actttgatcg gacagcctta tcatcatgag aacgaaatcg tttatgtaga
     8101 taatgataac cagcttctag gtaaacaagc aacagaattt ttgatccaga atggacataa
     8161 gaatatcctg tttgtgacaa acacgactca tgaaagtttg tatttcgaac gatatttcgg
     8221 ttatcaaaaa gcaatgatga tggctggtct tcctgcgtta tccagtgtag tactagagca
     8281 tccggaggat tatctgtcct ttgagaaaac gttgaaagaa aacgaagcca cagcattggt
     8341 ggtcattgac gatatcttcg cccttcgcac gatgcagttg gcgcaaatgt atggctatgt
     8401 cattccagag acactctccg tcattagctt caacaactcg atcttctcaa cattaacaca
     8461 cccttacctt acaagtatcg atatcgatat ctccgaatta ggacgtgtcg ctatgcaaaa
     8521 gctgcgcgaa ttgatccatg aagaattgag cagtggcgta cgtttggtca tccctcatcg
     8581 cttgatcaaa agagagacag tcgttccttt agaaaaccca tactaaatag ctgactcact
     8641 aaatacgctg accatttatc ctatggtcag ctttttatgt aaaagaagat actacttcta
     8701 acacattgtt tatctgtaaa aaagagcgtg ggacaaaagt aaagaacact tttgtctcac
     8761 gctctaaaca cgtataaacg gcggaagcag aagcaactcc ttcggaaata agctgaaatt
     8821 cacaaaaatt taaaaagcaa ttttcttgag tttcttctta tttcttggag ttaaacgctt
     8881 ctgtcccagc ctcttttttc cttccttcaa ttttttacac gtcgacgatt caataaaaaa
     8941 ccgcctaata ttgtaaagac aggtgcaaga atcgagaaaa aggcgaatgg caagtaatgc
     9001 aacgcgctaa ctttcatcgt tcccataatg aatgtgccgc tgactcccca cggtacgaga
     9061 gaattgacgg tcgcacctga atccgctagt gttcgtgtca aataggtttt tgataagcca
     9121 acgtcatcaa aagaacgctt gaatgtttct cctggaagaa tgatggacag atactgttct
     9181 ccaacgatca gattgattcc gatacagctc aaggcagtaa acccgactaa acgagaaggt
     9241 cggtccatct tttcttttaa ttcttgaacg atggtatcaa cgatcagata tttgatcagt
     9301 aacccaccta atgccaatgc aagtaaaatc aaactagcag aacctaacat actcatgatc
     9361 ccgcctcgag aaagcagttc atctagcttt ggatcaggtg tatttgcgac ataaccattc
     9421 atcaagatgt ctgctgcttt tccgaccgtc aaacttttct catggataaa agaaagaacg
     9481 agagcagctg tcgatcccgc tagtaatgta gggatagccg gaattttttt gattgccccc
     9541 ccaaataaaa taactagtgg aatcaatgtc caaggagaga tccaaaagct cgctttcatg
     9601 ttttggatca tttcattgat actagctaga tcggctgaat gactgttatg tcctaatatc
     9661 gtataaaaaa tcaacgaaag gacgaatgct gggaaatccg tataacgcat accagcgata
     9721 tgttcgaata gattaactcc tccaataccc gctgccaagt tggtcgtatc tgataaaggc
     9781 gagcagttat tccctaaaaa ggcaccggaa acgactgcgc ctgtagtcat tgcatcattg
     9841 aatccaagta aatgaccgat ccccaaaaaa gcaattccaa tcgtcgaaat cgttgtaaat
     9901 gaactgccga cagtcactcc gacaattgca caaacaagaa atgctgtcgg taaaaagaaa
     9961 cgcacagaaa caagtttaaa tccataaacc ataatcgtag ggatggttcc agataaaatc
    10021 catgaagcaa ctaagacacc aatcaaaaga aaaatcagga ttggaatgat ccctggagtg
    10081 attcctttga tgatcccgtc atggatctca tcccatgtga actttttaaa tctgccataa
    10141 aacaacaaac acatgaaagc tgcaaggatc gggatatgtg gcgagagctg gaatccgatg
    10201 atcagtactc ctaggagtgc caacaacacg atcaatacag cgatactttc ttttaaagaa
    10261 atatttttat tcatcgtcga tctcctattt caaatgaaaa ggccctgcca tgaaaaaa
//
LOCUS       DADGHT010000100        10301 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.101, whole genome shotgun sequence.
ACCESSION   DADGHT010000100 DADGHT010000000
VERSION     DADGHT010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.101"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..320
                     /locus_tag="JX887_002368"
     CDS             <1..320
                     /locus_tag="JX887_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258311.1"
                     /translation="IAALLLILFIGRLTLKADLSNGQMTFIWAFFAVMMQSFMEDTLT
                     SYPWVPIIYILLAMAVHRYDEPEVAEEFYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQ
                     RYH"
     gene            530..1336
                     /locus_tag="JX887_002369"
     CDS             530..1336
                     /locus_tag="JX887_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1258312.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            1348..2568
                     /locus_tag="JX887_002370"
     CDS             1348..2568
                     /locus_tag="JX887_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1258313.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            2558..4144
                     /locus_tag="JX887_002371"
     CDS             2558..4144
                     /locus_tag="JX887_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1258314.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            4183..6321
                     /locus_tag="JX887_002372"
     CDS             4183..6321
                     /locus_tag="JX887_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1258315.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(6689..7672)
                     /locus_tag="JX887_002373"
     CDS             complement(6689..7672)
                     /locus_tag="JX887_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HAX1258316.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            8050..9441
                     /locus_tag="JX887_002374"
     CDS             8050..9441
                     /locus_tag="JX887_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAX1258317.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            9457..>10301
                     /locus_tag="JX887_002375"
     CDS             9457..>10301
                     /locus_tag="JX887_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1258318.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKK"
BASE COUNT         3429 a         1704 c         2032 g         3136 t
ORIGIN      
        1 ggattgctgc tttgctgctt atccttttta ttggtcgctt aacgttgaaa gcagatttat
       61 ccaacgggca gatgactttt atctgggcct tttttgcggt gatgatgcag tcatttatgg
      121 aggatacatt gacttcatac ccatgggttc cgattattta tatcctgttg gctatggccg
      181 ttcatcgata tgatgaacca gaagttgcgg aggaattcta tgttatggaa gaggcatatg
      241 acgatatgac ttatgatgat acatcttatg aggaacaacc agatagcgct cattcttcca
      301 ggatccaacg ctatcattga taggcacaaa atacgagaga ggctgtgaca accgtcgcag
      361 ccttttttgg tttattgcaa ttgtctagca tcttctgtaa aatagaaacg ttagagaaaa
      421 tcttgtatca tagaaaatta agaaagaaat aagaacgcag ctcggtacca aaaatatggt
      481 aaaatggcac ttgactgtaa ttcactgaaa atcgcttgga ggaacacaaa tgtttaaaga
      541 tttgtattta tttatgaagg acatttatca gaacagaaaa ttattgctac agttttcgat
      601 caatgacttc aaatcaagat atgcaggatc gtttttagga atcttatggg cgtttatcaa
      661 tccgctattt actgtattga tttattggct ggtatttggt gttggactga aagcacaaat
      721 gatcgatgca aaatacccat ttatcgtata tttagttacc gggatgattc cctggttctt
      781 cttctcagat gcatttgcat caactacggt tgtttttcgg gaatatactt atttagtaaa
      841 gaaagtcgta ttcaatattc gtatcttgcc cacgacgaaa atcctatcca atctgtacac
      901 ccacttattc ttcattctga ttggcatagc tgtcgcgctt ataaatggta tatatccttc
      961 agcaatgtct ttacagctga tttattattt attttgcatg tgtgctttct tgacaggatt
     1021 gacttggctg acggcatcga tccaaccatt tttacctgat atcatgcaat taattacgat
     1081 cgtgctgcag ttgatcatgt ggacattacc gatattatgg agccctaatc agtttgattc
     1141 aggtcttgta agcatattga aattaaatcc gctgtactat gttgttcaag gttatcgtga
     1201 gtcattttta agtgaagctt ggttctggga gcatggaaca tatactttgt atttctgggt
     1261 tttcacgtta gtaatgttcg taatcggctc tgcagtgttc cgtagattga aaccacattt
     1321 ttcagatgtg ctgtaaggag aatagctatg acagaatatg caattagact aaaagatatc
     1381 acaaaatctt ataatatgta cgcaaaacct tcggatcgat ttcgtgaagc cctcaatcct
     1441 tttaagaaat cctatcatga tgtattttat gcgttgaaaa acgtgaatgt agaaataaaa
     1501 aaaggtgaga tgatcggttt cgtgggagaa aacggatcgg gaaaatctac aatgttgaaa
     1561 atcattacgg gagtactgac accaacatcc ggcacgatgg aaatcgaagg aaaaatctca
     1621 gctttgctag aactaggatc aggattcaat cctgagtatt ctggctatga aaatatctat
     1681 ttaaatggaa tggttctagg attttcaaga gaagaagtcg atgaaatggt cgatgatatc
     1741 attgaatttg ctgacatcgg agaccatatt tatcaacctg taaaaactta ttcaagcggg
     1801 atgttcgttc gtctagcttt tgctgtagca atcaatgtga atcccgatat tttgattgtg
     1861 gatgaagcat tggcagtagg cgatcttgaa tttcaactaa aatgtatgga aaaatttaca
     1921 gaaatcaaga actcgggaaa gacgatttta ttcgtttctc atgatatcag ttcgattcgt
     1981 cgtttttgtg atcgttccta ttggttgaaa aacggagaag tcgtcgaata tggcgatacg
     2041 atggaagtaa cgacgaatta tgaaaacttt ttaaagaaaa aatcagttaa aacagtggat
     2101 cggaataaaa accaagtaga acggttcgcc gctccagata tcgtcgacgt gacgaaagcg
     2161 gaattgttgg ataaagacaa aaatccggtg gatatgctgg aacaaggaga aaaactatac
     2221 gttaaagtaa cttatgaagt aaaagatgat acaatcaaaa atccggtttt aggaattgcg
     2281 ctacgaacag tcgacaattt ttatgtatgc ggacttaata ctctactaga tggtatcaag
     2341 attccttgga aaaaaggaga gaatatcttt tatctggagt atgaaaagtt aggtttgtta
     2401 gctggtgaat attattttga cgttgcggtc tttgaagaaa atgcaacggt tcctttggta
     2461 tataagacaa agtacatgaa cttgtttgtc agcggttctt atatcggaga aggcatcgtg
     2521 gtcttagacc ataaatggga agaagggact catagcaatg aaatatgatt ttgaaatgga
     2581 cctagatgaa caaagcagtg tgggaaaaat tgccgcacag atcaaaccag gaagtaaagt
     2641 tttagagttt ggtcccggaa acggccgatt aacgaaacat ttaatcggag caaaacaatg
     2701 tgaagtgagc attgttgagt tagataagga attgttcgat tttgtcagcg aatttgctca
     2761 agatggattt tatggtgata tcgaaagttt tgagtgggca aactattatg ctggacagac
     2821 atttgattac gtcttgtttg cggatgtttt agaacatttg gtagatcctg gaaaaacatt
     2881 gaagaaagtc agagaatttt tgaatgaaga aggagagatc ctgattacat tccctaactt
     2941 ggcgcataat tctgtcatga tcgatttgtt caataaccaa ttgccgtggg cttcttatgg
     3001 tctcctagat gaaacccata attcttttta tactcatgat ggcttccaaa aagtttttga
     3061 aaaagcggga ttattcatta atattgaaga ttatttgtac ttagctgtag gtgatacaga
     3121 attaaaatca acttatgaag aattgccgga agctgtacgc tatgatttca aaatgcgacc
     3181 atttggtgaa gtctaccaat actttttctc attgatgaaa catccagtag cacaaagttc
     3241 cattgcagag ccacaaaatt ctaattatgt aaaagtgtta gaagtaaccc agcaaacgaa
     3301 acaagatgaa acaatccaac aaataccatt caataatttc acaggggaaa atgagacact
     3361 aagtttcccc gtatcagaaa caacagaaag aatggtgttt cgcttcgcgc aacaacctag
     3421 ctttatcgaa ttcagcgcag aagctgccgg agaaaaacta acatttatcg attcgaatgc
     3481 tgtagtcaaa acagtaaatg attgttattt gtttgatggg aaagaattac cagagttcgt
     3541 tctaacggat atttctggga aagaagtgac tatccattgt cactatcgct ttatcgggga
     3601 attgacacca acaatgaaag aattgttgga aacgattcgt cccatggctg aagtcacaaa
     3661 gcagctttct gagaaaaatg acgaattaga aagagaaaat catcatcttc ttgaggaaaa
     3721 tacaagacta gaccatacgt taaaaacaac cacaaatcgc tattgcacat tgttggaaag
     3781 tgatgaatgg acaataaaac atagactagg acgacgtaag aaagaaactt cgaaaaaaat
     3841 ccaagaaaaa gaactttcta tatgtattga cgagaaaatc tgggatgcag aaacaaaaat
     3901 attaaaaatc atcggatggg gaatcgctaa ttcggatcgc cagcccttgt cctataagtt
     3961 atcagctgac caatcgccat ttttcgaagc aattcctgtt tcacgagaag aagtcaatca
     4021 agcagaacag ctcgcaaaag gaacagaagc gggatttgag ttacgaatcc tttgcgagca
     4081 agaacgttca ttcttagtgg aagcagtagc tcaaaatggc caatcatgga tcattgaaat
     4141 gtaaataatg attaacttat aaagataagg agtaaacgaa tcgtgcaaaa aaaagaaatt
     4201 gccgtattta tcgatcaaat cactcgtgaa cgggccactg gcgatttgct tattgtgggc
     4261 tgggcaattg atgaagtgac caaagaaatc cctacgataa aggtagaaaa agaaaatgtg
     4321 attgctgaag caacacatgt cgtaagattg gatatcaatc atttatataa tcttgatgtt
     4381 aagacccaaa gcggttttaa ggtacgttta tcagggaaaa tgagaggaaa agccatctta
     4441 gacttccaaa cagcgagaca tcaaaatggc atagctgtga aattaaacgg taaataccct
     4501 tatgatgacg gcattgaatc ttcatgggaa agaaaaaaaa gattactgaa aaaagggata
     4561 aattatgcaa ggactcatgg cgtaaaaaaa gcgatccgtc gggtcaaatt ggaattgaag
     4621 ccaggatcga tcgactatgc agagtggatc agtcgtcatg agaaaccaga tttgaaagag
     4681 caaaggaaag aagcacaagg atttgcgtac cgtccattga tttccatact tatgcctgtc
     4741 tataacgttg aaatcaaatg gctcgaaaaa tgcattgatt cggtactgga tcaaacgtat
     4801 gatcattggg aactatgtat cagtgatgat gcttctactg atccagctat ccgaaagtgt
     4861 ctggaatcct atcaagcaaa agatgataga atcaaagtcg ttttccgaaa agaaaatgga
     4921 cacatcagtc tggcaactaa ttctgcattg gaaatagcag aaggagaatt tatagcactc
     4981 ttagataatg atgatgaatt accgccattt gcattatatg aagtggcaaa agtgctaaac
     5041 gtacatccag aactggatgt gatctacagt gacgaagata aaatcgatgc agatggcaat
     5101 cgctttgatc cgcatttcaa agcagactgg tcgcctgata cattgatggg aaataattat
     5161 atctctcact taggcgtata tcgaacaagc attgttaaag aacttggcgg tttccgtaaa
     5221 ggctatgaag gttctcaaga ttatgatttg gtccttcgtg tgacagaaca aatccctgca
     5281 gatcatattt accacattga ccgagtcttg tatcattggc ggacgatccc aggatcaact
     5341 gcaagtaatg gcgaagccaa aagttatatc tatgattccg gagtgaaagc attgacagat
     5401 gccctgtcta gaagaaacat caaaggaagc gtacgtcctg gcagaatttc tggattttat
     5461 gagattgctt atgacgtctt gcaagaggat ttggtcagtg tgatcattcc aacgaagaat
     5521 ggctatgaag atctaaaaac ttgtgtggat tcgatcatcg aaaaaacgtc ttattcaaat
     5581 tatgaaatca ttattgcgga taacggaagt acagatccaa aaatgcaaga attatttgca
     5641 gaatacaagc atcagctgaa agaccgcttt atcgtagaat tgattgacat tccattcaat
     5701 tattctcgaa ttaacaattt agcagcagaa aaagcaaacg gcaaatactt tttattcttg
     5761 aataacgata cagaagtgat tgagccagat tggatgacgg tgatggtttc ttatgcacag
     5821 tttgatcgaa tcggctgtgt aggagcaaaa ctgttttatc cagatgatac aacgcagcat
     5881 gcaggagtat tattaggaat cggtggtgtt gcagggcatg cattgaataa ctatgatcga
     5941 acacattgtg gttatttcgg ccgattggtc attgacgtca attacttagc agtcactgca
     6001 gcttgtatga tggtcaaggc agctgacttc aatgctgtta acgggtttga tgaaacatta
     6061 gaagtagcat tcaacgatgt tgacttgtgc ttgaaagttt atgaactggg tcgttacaat
     6121 gtctatgcac atcaagcaga attgtaccat ttcgaatcta aatcaagagg ttatgaagat
     6181 actccagaaa aacaaagacg ttttgctggt gaaatcaaaa aaatgcaaga taaatggcca
     6241 gcatatattg cgcatgatcc attttacaat gataatttaa caaaagaagg aatcggcgac
     6301 ttttcgttga gaccagatta aactataata aaaagctgtt atgttgtgat tcgctcgcac
     6361 ataacggctt tttatagttt tttgtcaaaa aaaggcagaa ggtgccgact caaaaaaata
     6421 agtcgaggtt gggacagaag tgtttaactc cgagaaataa gaagaaattc acgaaaattg
     6481 cttttcaaat ttttgtgaat ttcggcttat ttaagaagaa gttgcttctg ctcccaccgt
     6541 ttattcgttt ttaaagaatg agacaaaagt gtttcttact tttgtcccac gctcttattc
     6601 atgctcagag cgccaataga tacaaaatca tagccaaagt ttcacgaacc ctagctgtca
     6661 aagaatcgat attttatttt aatataggct attttaaaat aaatggttta aggtattcct
     6721 ctacaaaagc cactctatca attatcatgg gtttaaaata agaagtgatg gagataacca
     6781 gattgttctt agcgtcaata taaagaacat ttccactatt accaattgct gaatatattt
     6841 cgttctcaga atctaatacc caccataaat agccatatct catattttgt aagtcttcta
     6901 aagcactggt tctaggtttg aacatctcgt ttatccacat gggtggtacg atttgttttc
     6961 ctttatacat ccctttattt aggcataata caccaatttt tgccagatca cttgccgata
     7021 aacacaaacc atatcctgcc gtcccgatat ttagtggatc acaaaaccag acattggttt
     7081 taggagactt atccattgta aactgcttat gttcttcagc tgtttcagca taataattga
     7141 catggtttgg tatccctata ggatcaaata gatacttatt ggcaaaatca acagttgtta
     7201 gcttacttgt ctgatacaac aagccagtta atatgtgtaa acagacagtt tgatagttga
     7261 attcgccggt tatacctttt cttcctccca ataaatctag tgatgttttt gtccaatctt
     7321 cacttgaaca gacttttgtc catggatcgc ctttacattt gtagggtgct ttcattgtta
     7381 gcaagtgctt gattgtaata gcgtaaatag ttttctcccc gcgtttcact ttatactctg
     7441 gaaaataatc taatacttta tcatcgatac ttttgattaa tccttgctct aaagcaatgc
     7501 caatcagcaa agatacaata cttttcgttg ctgacatgat atgacaagta tcgtcttttt
     7561 tataaccatt ccattcatct gtataaactt ctaccccatc cttatatgcg acaatttgac
     7621 atatatttgg ttgtcgaaaa ccaataaaat catgcaactc ttgtttattc ataagatatt
     7681 acctcacttt cttctataag cataatgtca ttaaaaatcg atttcaattt tttcgattct
     7741 tcacgtaata caggtattct tatggactag acagcgcttt gggaagatgg attctctgaa
     7801 aaatataaag gttcacttta tgagtggata aaaaaagcag caaatacttc gacttcttta
     7861 atttaccaac attagtgaaa atcgattcat ctggagattt gtaatttaga gtccttgtct
     7921 tgattagagg tgtataaagc tttttattag acatttttaa attccattac aatttgctta
     7981 taaactaggt ttttaaaggt gactatggta agataataga gatattattt tgtgattagg
     8041 agtgtatata tgaataaaaa tggagaatgg agtgctgcac gacggatatt cattatatta
     8101 atggatgtta ttgtatacaa tgcagcaata tatagtagtt tcttactgaa gtttcgtgga
     8161 gagatcccat tacgaaattt agaaactttc caacactcag caattattat ttcagtgatt
     8221 tttattgcgt tgaacatttt gttgggtgca tatgtttttt ataatcgaat gatcagtgac
     8281 atcgtgtttg tcacagtcat cggtcaggta ttgatgacac tagggatcat ggtagtgact
     8341 tttgcgggcc gctggtttgc ttttccacgt cttgttatct tactttcatt tgttctcggt
     8401 acgcttttct taagtatcta tcgtattctc gtatataaac tttatttacg cgtaagtcga
     8461 gataaaaagg tcgtcattat tgggttagaa aaggatgtcg caccagcaat ccaaaatttt
     8521 ggttcaaaga aaaacaacaa acataaagtc gaagcagtca ttcttgataa ctattatgca
     8581 aacatcaaaa atatgattaa agacatcgat attgtctatc ttgcttctca tatcgaagaa
     8641 actgaaaaaa tcaaaatcta tcaattagtt actaaaaatg aaaaaaaatt gtttttgaat
     8701 acaacatttg aaaacttgac attgatcaat ccaaatatta tgaatttcga agatgaaagt
     8761 attattgaag catctggatt tagaatccaa cctgaatatg aactattcaa acgtttgttt
     8821 gatatcatcg tttcacttgt tttattagtt attgcttcac catttatgtt attcacagca
     8881 attttagtca aagtgacatc accgggacca atcatctata aacaagtgcg gatcacaaaa
     8941 aatcaaaagg aattttcaat ctataaattc cgctcgatga ccgccacagc cgaagcaaaa
     9001 tctggaccag ttttagctaa gagcaatgat gcacgagtaa cgcctgtagg taaatttatt
     9061 cgagctgtcc gctttgatga attaccacaa atcttcaatg tgctgaaagg cgatatgtcg
     9121 atcgtaggac cacgtcctga acgtcctttc ttcgtcgatc agttcaatgc agaaaaccct
     9181 tattactact tacggcataa tgttcgtgct ggtatcactg ggtatgcaca agtctatgga
     9241 aaatatgtct ctgattacaa cagtaaatta cgttttgatt tactttatat caaaaaatat
     9301 tcattgatgc ttgatttaaa gatcttgctg caaaccatca agatcctatt tgataaaatg
     9361 tcctctcaag gacttgaaga agacgaaaat gtgatctcat tggcagaaat tgcttttccg
     9421 aatgaaaaaa tctttcgcta gttgggaggc gtaaaaatga acaatccgaa attcagcata
     9481 atcgtaccag tatacaatgc agaagcaact attggtcgaa cgattgatat tctaaaagaa
     9541 ttggattatg aagagtacga agtcgtttta gtaaatgatg gatcaacaga tcaaacacag
     9601 gaaatcattc aagaactgat tgaaaatgat gaacgttttg aattgattac tacgaccaat
     9661 caagggcccg gattagcaag aaacgaagga ataagacagt caaaaggaga atatctctta
     9721 ttcttcgatg cagatgacac gccagtaaaa acgatcttgt cagattatga tcatttgcta
     9781 gaaaagagtc caaaagcgga tcttgttgtt agttcgtttg tttttcgtac aatggacgag
     9841 ggaagaatcg tttccgaaaa agaaaactta gttacagaat gtcactatct aactcacgaa
     9901 gagtttataa aagacatgta tcagttaatg aatgaacagt tgatgtatgt tgtatggaac
     9961 aaatgctatc gtagcgatat tctgaaaaat aaccaaattc tatttaaaac ttataatagt
    10021 tgtgaggatc gaatatttaa cttacattat tatgaatact gtcatcaagt gatcatgaac
    10081 ccaaaagtag aatatattta tgaatttgaa ggtgggaagg ggatcactaa tcaataccga
    10141 cctaacaagt tcgaaacatt taaagaattc tattcattag caaatactgt aacagacgat
    10201 attaataaag acggtatggc ggcgcttctt ttaaaaggga caacttcagt tattttttct
    10261 atttatagta cctctgcaag aacttcaaaa gagaagaaag a
//
LOCUS       DADGHT010000101        10134 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.102, whole genome shotgun sequence.
ACCESSION   DADGHT010000101 DADGHT010000000
VERSION     DADGHT010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10134
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.102"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(634..1614)
                     /locus_tag="JX887_002376"
     CDS             complement(634..1614)
                     /locus_tag="JX887_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAX1258319.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
     gene            complement(1627..2505)
                     /locus_tag="JX887_002377"
     CDS             complement(1627..2505)
                     /locus_tag="JX887_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAX1258320.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            complement(2521..3321)
                     /locus_tag="JX887_002378"
     CDS             complement(2521..3321)
                     /locus_tag="JX887_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HAX1258321.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
     gene            4713..5039
                     /locus_tag="JX887_002379"
     CDS             4713..5039
                     /locus_tag="JX887_002379"
                     /inference="COORDINATES: protein motif:HMM:NF013698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAX1258322.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            5047..5955
                     /locus_tag="JX887_002380"
     CDS             5047..5955
                     /locus_tag="JX887_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAX1258323.1"
                     /translation="MCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSEKNRALNCLT
                     VSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEEIQAAVEGAI
                     SVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGLDTQPITAIA
                     ILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKPLLVQIANAL
                     LRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSAKGYLEPKPA
                     KEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            6584..6835
                     /locus_tag="JX887_002381"
     CDS             6584..6835
                     /locus_tag="JX887_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAX1258324.1"
                     /translation="MKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESLD
                     SFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
     gene            7377..7535
                     /locus_tag="JX887_002382"
     CDS             7377..7535
                     /locus_tag="JX887_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1258325.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            7607..8833
                     /locus_tag="JX887_002383"
     CDS             7607..8833
                     /locus_tag="JX887_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1258326.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGIASEKYQKVFPTRQLAIKA
                     EREMKKKIETVLREENANSLELKGKIKFKDFYESKWLPRYELGQTTRSNRAPSNVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILCYIEFNRTTKIIQCITAPKKMALEEKRIREGNQALSSEELTDWIEAVNNDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFNKNTVRLKYALDKYQRKTHTKGWKDTV
                     IQAPEVVMTLLREWKSAQAEQLLKLKIIQTPDQYLFTYSKPSGEVNCPVHADYLNYRI
                     NAIKKRHPELAQLSPHKLRHTYATIAREGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKSVFEAFQKGLNKCD"
     gene            complement(8922..9314)
                     /gene="rpsI"
                     /locus_tag="JX887_002384"
     CDS             complement(8922..9314)
                     /gene="rpsI"
                     /locus_tag="JX887_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAX1258327.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(9330..9773)
                     /gene="rplM"
                     /locus_tag="JX887_002385"
     CDS             complement(9330..9773)
                     /gene="rplM"
                     /locus_tag="JX887_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAX1258328.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLAGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
BASE COUNT         3152 a         1958 c         1726 g         3298 t
ORIGIN      
        1 gcggcgcaca gaacgcgccg catatcggac taagttttat tcaaatttgt cttcgccaac
       61 acaatttgac gaagagcctt ttctttcagg aagacttcgg taatttttag gagttctacc
      121 tattctttta accgtttatt ctctttttct aagcgtgtaa tttcatttct gcgaatggat
      181 ttcatgactt cctctaccga gaaaagtacg ttatccatat ttttcaactt cttgaactca
      241 tcaatacacg ctattagagc gagcttctag ctatagacta acttctttaa cagaaaaccc
      301 ttcttccgtt accagtttta cagcggtaat tttaaatatt tcatcaaatg aacgtcttgg
      361 cataatccag atcttcgctt tctcttaatt tggtgtcaat tttagtataa cccgtccaac
      421 ttatttttta actaagtgcc cggtttttct tgacaactcc acccaaaagt tagatttttt
      481 ggtctaagtt ttagggtcgc ttcattacta gaattcaaca agagatgttt tttattttat
      541 ttaaattatg gggtcagttt ccatttgatt acaaacttct ttgttttctt tttttaaacg
      601 caataataaa ggttttaatt tcagcctttt taattagaaa atcaattttc ccaaattatt
      661 ttctttagct ttcttaacga tttctgtcgc aactaccaca tctaatacag ccgaaccaac
      721 tgttttgaag atcgtgattt gttctccact tgtccgaccg atcaattctt cattgatcag
      781 ttggcctagt tccccatgat agctgtctct ttgaatatac ccatcttgca gcggtgaaat
      841 gaagtcccca gcttctttta gaacaccgtc catggtatca aaaataacaa catctgcggc
      901 tttgattatt tctcgtggaa tttcacacat ttccggtgtg taagcaccga ctccattgat
      961 gtgcgcacct tttttgaccc actcagcaga gaatgtcgca cgttttgaag tggtcacact
     1021 tgtaatgatg tctgctcctt caacgcattc ttgactggtt tttgttgggc gcatcgttac
     1081 agaaaattgt tgcatcattt tttcagcaaa ttggctggca cgctcaaaat caatatcaaa
     1141 aatccgaact tcttctaatt tacgaacggt caacattgct tctaattgtg actgtgcttg
     1201 tccgccggtt ccaatcagcg cgccaatttt agcatcttct cttgcaagaa gttctgttgc
     1261 tgctccttga acagcgcctg ttcttaattg tgtcaaataa gtaccatcca aacaagcgga
     1321 taccataccc gtttctggat ccaatacgat catcgttgct ggtacacttg gtaagttttt
     1381 cttgatgttt tcaggataca cggaaacgat tttgacacct agcgcgcctt cgccaccttc
     1441 tacataagca ggcatatata agctttgtcc gttgcttttt ggcacatcga tattggtgcg
     1501 aagaggcaca cttgcctttc ctgctgaata caatgacagt gcttttttgt ccgcatcgat
     1561 ggcttctctc attgaaaaac ttttgataat atcttctttt ttaagaaata acatttgaat
     1621 cgctccttaa ttagctgctg taactttttt taattgactg cccaacatcg tatatgcact
     1681 gtatagtaag accaaaatca cgatccattt caggatatag gtatctaaag atttgactag
     1741 gaatacagcg accaataccc ccaatacacc gaaggttgaa gtaaaaagtg tgatttttct
     1801 gctgtattca ttaaatttaa tgaattgaac actgccgatc ggtactgaga aggtacaagc
     1861 ccccatcata ataggaaagg ctgcaactgg attcaagcct agcaagtaga cagttaccat
     1921 cgttaacgca taagaaccaa tgccgatatt gttcaatgca ccatagacaa agagtaaaaa
     1981 tcctgccaag attaattttc cgccatacaa ttcactggct gttccgtttg atggaatcca
     2041 gttcatttgt cctgcaaaaa tcaacaatgc agcaatgacc aatcctatgc cgacaaacag
     2101 tttgatcgtt ttctctggta acttcacgac aaatcttggt cctaaatatg caccgataat
     2161 ttggcagata atacaaacag ctagtgtctt gatccctacg ttgatggcag tgatgtaaga
     2221 caatgccatg acggctaccg gtactacaca ttgggtattc aacgttccgg gtagtttttt
     2281 catgctgacc catttcaact ttggataaag gacggttccg atagcaaagt cggaaacgcc
     2341 aaatgttgaa agaaagaaga tgataaatga cgtgaagggc aacagacgca tatcccctgg
     2401 ttcttctttg aaattttgtt tgtttttgaa aaggtctctt agaaagtaaa taataaaata
     2461 tagattgatt gcgacaatta gtgtcagcaa aatattccga atcataaaaa attcctccta
     2521 ctagtaaatc tttctgattc cctcaaagcc ctcaccatat tttgctttaa gttcttcagg
     2581 agattctgca atcactttta gtgtatatgc atcatgtttg acatattctt ttgctagatt
     2641 gaccatggcg tggttttttg tccaagtgac atcggttgat tgcagttctt cgttaatggt
     2701 accaaacacg acttcttgct catcggcgac gatgttgatc catcttgctc caaagtcagc
     2761 aagtttgtct gtttcaaaac catgaatata atacttttct aagggaagat catattcatg
     2821 ggtagaactg aataaaatca gtacaaactt atcaactctt ttttcagctt gctgcaatgc
     2881 ctttagtagt gaatccgtga aattctcatg ccaaacttga atgagcaaac tttcttttgc
     2941 gtttttcacc aaatgctcta ctttatccag aacatactcg ataccatcaa ctttccacag
     3001 catttcttct tcatcttttt ctttgatcat ccctagattc ttggtaagaa aagaaagatc
     3061 atttttaaca cttttttcta atttctctaa aaactcattt gccgagatgg catgataaag
     3121 tttaggttct gatttattaa cgacaatcaa attctttttt aatagttttt ccaaaatatt
     3181 atatactttc gagcgtggca cacctgagat tttacttact tcatatcctg taagattacc
     3241 tttttctaat agtgtggtat acactcttgt ctccatctct gaaaaatcat attttttcat
     3301 gatttgaata atcgtttcca ttgattaatc ctcactttat ttttagtagc tactacggta
     3361 acaactataa attctttttg attatctgtc aagagttagt tcaataacac acatataata
     3421 attagcttaa aaacaatctt tttattaaaa agaaacatta taatatgaat gtttgtgaaa
     3481 aaataataca acttagtcat tctttacaac gatttataga aaaacaacct ctttaaatat
     3541 aaaaggtacg ggttactgat tacttgtaaa tctttacgtt ccagttttat tctttctaaa
     3601 aaatatactc acttcttttc ttagacttct ttttttgatt ctcctcttta tggtcttgtc
     3661 cttttttgcc ttcaaaatat ttaaataaac ccctttcaaa agcatttcta ggttttggac
     3721 aataaggaat gacttttttc ttcatataaa tacctcattt aactatttga tatcatcaca
     3781 ttatcaaaaa aaataggttt tttattaaaa ctatcttgac ctttcgggag atttcactgt
     3841 gatttatttt tattcccata cttttttcgt tggtcacttt cgtataccta atctaagcga
     3901 tcatcggcga cggtgctttt acaacgaatg gcaggacaaa acaaggggcg gaaaaacttt
     3961 tttgcctatt tcataaaaaa ctttttccta cagcaatccc ttgttttgtc ctaccacacg
     4021 ttgtgaaccc aaagcacgcc gacgaacgct tagctatacg aaaatgacct ccaaaaacaa
     4081 aaaagtgagg tgaatagaaa caaaaagaaa ttgaaatctc ccaaaatgtc gtccgcctcg
     4141 gagacaactt gctgctgaaa atggttggtt aattcattta agtattaaat aagataaatc
     4201 atcaaattaa tcggaaaaat agcatgattg gccttatcaa aaataaactg taaaaactta
     4261 tatttctatg agtggtggaa caatgctaat accaaattaa tttatcgatt acccacctgc
     4321 acaaaccaaa gatagcatta ttaggaaacg aatcaatcag cgaatccagc attataatga
     4381 ggatactaaa aataaagttt tcataattat aaatccgcct tcctacgaaa ggcaccaatg
     4441 aggtgatgaa aaccttagag cgctttcttt ctttttttat tccgtgttac cctttccttg
     4501 caggtccctg gtacactaca gaacccgagg aggtgagtgg cggggctgta tagcggcaac
     4561 cccgcataat tatatggtgt cggtcatccg ttaaggcatc aatgaatggc gcaaacccgt
     4621 agcccgtaaa cttatctctt ccgaagttga ctcgatttcg ccggatgacc agtccctacc
     4681 aaacctgtac tattttttta caggaggttg ctatgttcaa aatctttcgt aaaaattgtt
     4741 gtggcttgga tgtccacaaa acgtggatct atgcgtgtat cggaatcaca gatgcgaatg
     4801 gtcgtacagt gtataagcaa gctcgcttct cttcctttac aaaaggtctc aatgaattag
     4861 ctgaatggct tgctaaatac aactgtaagg atgtgtgttt ggaatcttcc ggtaaatttt
     4921 ggattcctgt ttttaatatt cttgaaaaaa cttgttttgt cacactggct catccgaagt
     4981 acaccaaacc ccagaaagga aataaaacag atcgcaaaga tgcaaaaatg gatttgtgat
     5041 ctctttatgt gcgacatgat caaacccagt tttattcctg gtcttgaaat ccgccagctt
     5101 cgtgatctaa tgcgttatcg gacgaaactg accaacatga aaacaagtga aaagaatcgt
     5161 gctttaaact gcttaaccgt ttctaatctg aaactagatg atgtttttag tgatgtgttc
     5221 ggaaaatcat ccacttctat catccaatac ttgttagaac atcccggtga atcatttgat
     5281 gttcgaccat ttatccatgc ccgttgtaaa actcccgttg aagaaatcca agcggcagtt
     5341 gagggggcga tttctgtacc tcaagcgatt aagcttcgcc aatgcctcaa ccatattaac
     5401 gagattgaga agcatcgaga agagatcaat ctagagattc aagctcttgc agaacccttc
     5461 tcccctgttt tggaactact tcgtaccata ccgggcttag acactcagcc aataacagcg
     5521 attgcgattc tttcagaaat aggaccggat atgtccgtgt ttccaacttc gaaacacttt
     5581 atttcttggg ctggatgctg tccaagaaac gatcgcagtg cccgacgaac aaaatcaaca
     5641 cgtatctctc gtgcagggca gtcgttgaaa ccgctacttg tacagattgc caatgctctt
     5701 ctcagatcca aagaacatcc agaatttaaa aatcgctatc gtagaatcaa agcgaatcgt
     5761 ggacacaaga aagctatcat tgctatttgt aagatgctcc tgaccgctat ctggaatgtc
     5821 ttatcaaagg tggaacccta ttctgctaaa ggatatctgg agccaaaacc tgcgaaagaa
     5881 gagaaagttc tgacgcaatc ccaagctctg gaccttttaa gaaaacgcgg atataccatt
     5941 atagatagtg cttaaaccaa agttacgttg attcttccta aatagactcg ttgtcttcca
     6001 tttcaaaaat tttgaaaacg gtaggcttat ttagtgtacc gttcttcagg tatcttcaaa
     6061 tagatttatt ttcaaactta tttcctttct tcttttactc tcctatagct tagcatttaa
     6121 gtgggcactc gtgtcacctt gctagatagc tatgaatgcc gtaataagcc tcctagtata
     6181 taggcagact gccaattata actgattcaa tccacattat gataaaatcc accttttcgt
     6241 ttcatatgtg ttgaaatatc acatatgtca aaagtgcacg agtcttttca ttcagtgctt
     6301 tgtaaatact caaaattatt ccttttcact ttaaaaaaaa gataattagt acaaaatcag
     6361 aaatgaggaa agtattagga tggactagaa aggagttgtt gaatttgttg caacagattg
     6421 gtcatttatc aattaaaaat taggtgaagt tttattcatc actgcagctg ctgtttccca
     6481 gagaataaaa cgtctagaag aaactggtca gttactgtat tatcaagcag caattgacta
     6541 cgaacaagct tgattactaa ccaaagcgtt tatccacctg ttgattaaat caaatcaaaa
     6601 atcaggtttt tatacgttca taaaagcaat ctccagtgta ctcgaatgtg actgtatcat
     6661 aggtccttat tcgatgttaa tcaaaatggg gtttccttct accgaatcat tggacagttt
     6721 tatcaatgat ttatcaaagt ttggacgaac caacacccaa atcgttttct cgactcttgt
     6781 ttccttaatg gtttatcagt tctggaatgt ttatcatgcg cttttattaa aatagaaaag
     6841 agcttttttc atgcgacaaa gcagtgatca tttattggca catgcaatct ttgtggatcc
     6901 attttttgaa aatacgatat ttagttttga cccaaaaatc tttaaatacg tatttgataa
     6961 tttatcttaa caaccagata attttattca gcaccgtatt atctatattg aattctcgga
     7021 atcaagataa atttttttcc gtttttgttt cttttttaat cttcttcttg ttattaatag
     7081 tgattaggat gatattccta tattgatctt tgataattag atataatttt tgaataacgt
     7141 tccctgctat tcgagctaga aatacaagta cgccatgacc tagttagcga caactactta
     7201 gagatttctt ttgttctggg acaacaaaat gccatgacaa tagcagtaaa taatgatact
     7261 tccgtaaggc tcgccgtaaa ctggggagag gtgaaattcc tatgtgctta cccaaagcgg
     7321 ttcaaaaatt ttaaactatt attttaggag atgattttat aaaatcgaaa gcctacttga
     7381 ataaaaaaca agcctgtgaa tttctaggaa ttgataataa tactttagat aagtggattc
     7441 gtgtatataa ttttccagta ataaaaattg atggcgtagt tcgctttgac gtagaggata
     7501 tcaaagattt catgaataca ttcaaaaaaa attgaaattt tcttctcgtc acatatacta
     7561 taaatagcga aatgtactgc cttacttttt aaaggagtga ggaagtttgc ctacaaagct
     7621 ttcaaatggg aaatataaaa ctaatctgag gtatccaaaa aaattcagag aaatcactgg
     7681 aattgcatca gagaagtatc aaaaagtatt tccaactagg caattagcta ttaaggccga
     7741 aagggaaatg aaaaagaaga ttgaaacagt tttaagagag gagaatgcaa actcactaga
     7801 attgaaagga aaaataaaat ttaaagattt ttatgaatca aaatggcttc ctagatatga
     7861 actaggtcaa actactaggt caaacagggc tccaagtaat gtaacaatta gtaatactaa
     7921 ggatatattc cgattgcaca tccttccaat gtttggtgaa tatgcaatga attatctgaa
     7981 ttcaaatact gagataatat cagatgaatt aacaaagaaa tcgaaagaat acgcaaatat
     8041 aaaaattatc aaaggctatg ttcgctctat gtttgatatt gccgaaatac tatgttatat
     8101 cgaattcaac cgaactacca aaattattca atgtattacc gcgcctaaga aaatggcttt
     8161 agaagaaaaa aggataaggg aagggaatca agcattatca tcagaagagc tgactgattg
     8221 gatagaagca gtaaacaatg acttaaataa tcacttgctt acacttcacg attacacact
     8281 tttcatgctt accttatatc taggtgatag aaaaagtgag acttatgctc tgcaatggaa
     8341 atatattgat tttaataaaa atacggttcg tctcaaatat gctttagata aatatcaaag
     8401 aaagacacat acaaaaggtt ggaaagacac cgttattcag gcaccagaag ttgtgatgac
     8461 attattaaga gaatggaaat cagctcaggc tgaacaattg ttgaaactaa aaattataca
     8521 aacacctgac cagtacctct ttacctattc caaaccttct ggagaagtaa attgtcctgt
     8581 tcacgctgac tacttaaact atcgaatcaa tgcaataaaa aaaaggcatc ctgaattggc
     8641 tcaattatct ccacacaaac ttcgtcatac ctatgcaact atagctaggg aaggtggagc
     8701 aaatatgaat caaatctcta atgctttaac gcactcggat atttctacta caaaaatata
     8761 cgtgaacaca cctgacgtag ttgataaatc tgtttttgaa gcatttcaaa aaggattgaa
     8821 taagtgtgat taacatgtgt tctcaaatgt gttcttatta taaaaaaaga cactttccaa
     8881 ataattgaaa agtgtcctga aatattgata taaaaagaat attaacgttt tgagaattgt
     8941 gaagctttac gagctttttt aagacctggt tttttacgtt cgaccatacg tgcgtcacga
     9001 gtaagtaagc cagcacgttt aagagctaaa cggaagtcag gatcaacttc tagcaatgca
     9061 cgagcgatac catgacggat agctcctgat tgtccagcgt atcctccgcc gtttacgtta
     9121 acaaatacgt catatgcgcc ttttgtttca gtaacagcga aaggttgatt gattacttca
     9181 cgcaagtcag catgtggaat gtattcttca acatcttttt tatttacagt aattttgcca
     9241 gttcctggta ctagacgtac gcgagcaact gcgtttttac gacggcctgt gccgatatat
     9301 tgaacttgtg ccaatgaaat tccctcctat tagattaagt ttgtgatgtc taaaacttct
     9361 ggttgttgtg ctgcatgtgg atgttctgct ccaccgtata cgttcaattt tgtaaattgt
     9421 ttgcggccta aagtgttttt aggaagcata ccttttacag aagtttcgat caaacgacga
     9481 gaatttttag cacgcaattc gccagcagtg attgatttca atcctcctgg gtagttgctg
     9541 tgacggtaat aaattttgtc agtcgctttt ttacctgcta atttcacttt gtctgcattg
     9601 atgacgatga cgaaatcgcc agtatccaaa tgaggtgtga aagttggttt atttttacca
     9661 cgtagtacag atgcaacaac tgttgaaaga cgtcccaatg gaacatcagt tgcgtctact
     9721 acataccatt tacgttctac ttcgcctggt ttggccatat atgttgtacg cacgttattt
     9781 tcctccaatt taagttctga tgtttgacat acacttcgag tttccggggc tctttgtggg
     9841 gcaaacaata ccatttaaca tattacccgc taatctagtc aatgtcaacg tttttctgct
     9901 tgattgaaaa atttatatga aactttactt cttttctttc ttttatataa aagggtcgtt
     9961 tcctgtcaaa atgaaaaaca aaaagaggct gtgacaaaag tcttgtcaca accccttatt
    10021 ttgaataaac ggtgttctcc tgccaactcc tcggtcacaa gtcacaatat ccataaaaca
    10081 taagaagctg ttttttaaaa ttgtttcttg tgactcggag ctgaacggca ggct
//
LOCUS       DADGHT010000102         9969 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.103, whole genome shotgun sequence.
ACCESSION   DADGHT010000102 DADGHT010000000
VERSION     DADGHT010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.103"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="JX887_002386"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="JX887_002386"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAX1258329.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="JX887_002387"
     CDS             complement(1173..1868)
                     /locus_tag="JX887_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAX1258330.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="JX887_002388"
     CDS             complement(1881..2597)
                     /locus_tag="JX887_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAX1258331.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="JX887_002389"
     CDS             2927..3532
                     /locus_tag="JX887_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAX1258332.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="JX887_002390"
     CDS             3857..4180
                     /locus_tag="JX887_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAX1258333.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="JX887_002391"
     CDS             4362..5732
                     /locus_tag="JX887_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAX1258334.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="JX887_002392"
     CDS             complement(5862..7163)
                     /locus_tag="JX887_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAX1258335.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9384)
                     /locus_tag="JX887_002393"
     CDS             complement(7393..9384)
                     /locus_tag="JX887_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAX1258336.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDKVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="JX887_002394"
     CDS             complement(9528..9794)
                     /locus_tag="JX887_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAX1258337.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
BASE COUNT         2918 a         2070 c         1811 g         3170 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt tatcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcg
//
LOCUS       DADGHT010000103         9870 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.104, whole genome shotgun sequence.
ACCESSION   DADGHT010000103 DADGHT010000000
VERSION     DADGHT010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.104"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(18..263)
                     /locus_tag="JX887_002395"
     CDS             complement(18..263)
                     /locus_tag="JX887_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258338.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(378..956)
                     /locus_tag="JX887_002396"
     CDS             complement(378..956)
                     /locus_tag="JX887_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1258339.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1033..1563)
                     /locus_tag="JX887_002397"
     CDS             complement(1033..1563)
                     /locus_tag="JX887_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAX1258340.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1567..2427)
                     /gene="rlmB"
                     /locus_tag="JX887_002398"
     CDS             complement(1567..2427)
                     /gene="rlmB"
                     /locus_tag="JX887_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAX1258341.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2420..2815)
                     /locus_tag="JX887_002399"
     CDS             complement(2420..2815)
                     /locus_tag="JX887_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAX1258342.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2812..4224)
                     /locus_tag="JX887_002400"
     CDS             complement(2812..4224)
                     /locus_tag="JX887_002400"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAX1258343.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4221..4757)
                     /gene="cysE"
                     /locus_tag="JX887_002401"
     CDS             complement(4221..4757)
                     /gene="cysE"
                     /locus_tag="JX887_002401"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAX1258344.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(5079..6539)
                     /locus_tag="JX887_002402"
     CDS             complement(5079..6539)
                     /locus_tag="JX887_002402"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAX1258345.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6709..7866)
                     /locus_tag="JX887_002403"
     CDS             complement(6709..7866)
                     /locus_tag="JX887_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAX1258346.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7900..9270)
                     /gene="radA"
                     /locus_tag="JX887_002404"
     CDS             complement(7900..9270)
                     /gene="radA"
                     /locus_tag="JX887_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAX1258347.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9333..9860)
                     /locus_tag="JX887_002405"
     CDS             complement(9333..9860)
                     /locus_tag="JX887_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAX1258348.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2507 a         2213 c         1784 g         3366 t
ORIGIN      
        1 tcaggctcgt ttgcttttta aactgcttca gttaaaaatt cgatctcaac tgtccgagta
       61 agtacatctg aatagctgta agatactcgt tcaaaagaat tttcttcagg atccaaatca
      121 acaacgaata ctgaaggata ggtttctgtt aaaacgccgc ggcgttctgt ttgacgcttt
      181 cttcctgtct gagcaaccaa catgattggg ctgccgatac gaccttctaa atctttcttg
      241 attgaagcta aagttgttgg catacagttc acctctacta tcaactatac cacatatttt
      301 taaaattttc aagtttacca taaaaaaaaa agaaatgcaa taaaaataaa taagaagctc
      361 attaagattt ttctaaatta ttcctcatta taaaatttca agtgtttttt tattttgagt
      421 tttactctcc cgtaagcgct cattacttgc ttgtgatcca ttgctaaaca ttcagccatg
      481 tctacaaaat caacgccttg catataataa tgaaaaattt tagcttctat ttttgaaaac
      541 tggatttcgc aattttcgat tgcttctttt aataaaagat gctgaatcgc taaaggttct
      601 tgcaatgtga tctctgctaa aaagtctggt ccttctgtct ctattttttg gtcgattgag
      661 acttcatctt tttgatcacg acgcttcagc gcgttctgct tcctcaacag agaatagatt
      721 tgattgctta taatgctttt ataataactt ccaaagctaa cacctttgct tttttcgtaa
      781 gttctcaatg cctgatataa agcgatcctt gcttcttgtt cccaatcctc agaaacataa
      841 tttcttaaat aataggtgtt tttcaaacgt agtaaaagtg gaaaatattt ttgatacagg
      901 gcagcaaatg cttcttcgtc accattacgt gcagcgcgca ataactcctc agacataaaa
      961 taattcctcc ataaattcgt ttatggagga atcttatcat caatgattca tcgaactgat
     1021 tagaacgata tgttatttat tttttctcat taaatcgtcc aatttttggg acaatttttt
     1081 taactgctct tcattccatg gagaattacg tcggaaatca ataaaatgca tatctttatt
     1141 ttcttgggct attgtttttt ccgttttttt tatcgtctta tataattcat aagcagaagt
     1201 tcgtaatgct ccttgggaaa agatcatcca ctgttctgct aaatcgcttg tcgccactgt
     1261 cacttgtgtc aaacggtcat tcagctgacc agcgattctc tcgatataac tgtcagccgt
     1321 ttcgtcttct ttcgtaaaaa caacatccaa ctggtatttc ttataatttt gttggatgcc
     1381 cggaactagt tgggcatcga agacaacgat gacttccatt ccttcatatt tcgcataatt
     1441 tgataaacga tgtaaaagag cttctcttgc atccgccatt ttgtcctgct ttttaagctg
     1501 gacaagttcc ggccacgaac caatcatgtt gtagccgtct acaatcaaca gctgtttttt
     1561 catggtctac tccccctgac gttgggaaaa agcctgatac ataagcaaac cagcagcaac
     1621 actggcattt aagctctgga cgtgcccggt catcgggatc gtcagcaatt catccatttc
     1681 ttttttcaat cctggactca ttcctttgcc ttcattacca atgactaaag caattgatcc
     1741 tttggcattc catttttgga agtttgtgcc ggtcatatct gtgccaaata cccaaaatcc
     1801 tgtttctttg agctgttgca cagcttgtac caaattcgtc acgcgtgcaa cagggacatg
     1861 ttcgactgcc ccagtggaag tctttgttac gataggtgtg attccaactg ctcggtgttt
     1921 tggtatgatc acaccatcga cgccacttgc gtctgctgtc cgtaaaatcg acccaaaatt
     1981 gtgtggatct tcgatgctat ccaaaatcaa aaagaagggg tcttcttttt tctcttttgt
     2041 tcgttcaatc agttggtcaa gggataaata ttcataaggt gtaatcgcaa gaacgactcc
     2101 ttgatgcacg ccgtgatcgc tcaaagtttc taatttttgt ttaggaaccc atttgactgg
     2161 cacagcttgt tcacgtgcga tttctttcag ttcttctact ttttctcctc gtgaatcttc
     2221 ttgaagaaag agtttattcc ctcgcccttg ttgtagcgct tctactgcgg catggtgccc
     2281 aaagacgaaa ttatcttcta atgcttcttc attttgatca gaaactgact gatttcgtcc
     2341 agtttgcttt ttatttgaat atctattttg ttttttgtct tcaaatccac gtttcgattg
     2401 atgtttgttt gttctttctt tacccatttt tttcaccaac tttctgaata caccagcgga
     2461 tcaattcttc catccgctcg gtttgttttg tcaaatgcag atagcccatg agcgcttcga
     2521 accctgttgc gacccgatac gtcgtaacat cagcattttt tgcgctcgta tggcttttag
     2581 catttcttcc tctgcgataa taaagttctt cttcttctgt caaaagatgt tcttccagca
     2641 tttgctgaat caaaaaggct tgtgcattcg cagaaacata attcgttgcc gcacgatgca
     2701 gcttattggg ttttgtttct ccttgatcaa tcaggtggtc acgaacatag atttcgtaaa
     2761 tcgcatctcc aacataagcc aaggctaaac cgttcaattg tgtgtaatct ctcatgcttc
     2821 tcttctccat cgggttcctt gcggtgtatc ttctaataag atcccttttt ctttcaacaa
     2881 atcacgaatt tcgtcgcttc ggacaaaatc acgattgctt cttgcttgat ttcgttcttc
     2941 gatcaattgt tcaatctctt catctaataa ctcttctgct gtaaataaaa taccgaagat
     3001 cgaaagccat tgcgagaata aagcttctcc ttgtgccaag acagcggcag aaactttcgg
     3061 ctggtctaga taagtgttca gccacttagc aagctcatag accactgtga tcccatttgc
     3121 tgcattaaaa tcatcgtcca tttcttcgat gaatcgctgt tctaaatttt ctaacaaagc
     3181 gattttatcc gcatcatctg ccaaattctc tgaggcagtt tcttggcgga atttcaaatt
     3241 gtcaaacgta ttcttcagtc gttgtaaatt ggtggctgct tctttcatcg tcgtttcact
     3301 gtagcggatc ggacgacggt attgtgtggt cgccatgaag aaacgcaaga cttgtggatc
     3361 aacgtttttg atcatttcat gtacagtgat gaaattccct agagatttac tcattttttc
     3421 atcgtcttcg ccaatcgtta catagccatt gtgcatccag taattagcga attttttccc
     3481 tgttttcgct tcactttgtg cgatttcatt ttcatgatga ggaaattcta aatcttgccc
     3541 gccaccatgg atatcgatcg tttctcctaa atgttttgtt gccataacgg aacattcaat
     3601 atgccaaccg ggacgtcctt tgccccatgg tgaatcccaa gaaatctcgc caggttttgc
     3661 ttgtttccat aaagcgaaat ctaatgggtc ttctttttgc tgctgttctt cccctgtacg
     3721 ctgacttgct ccgacttcca gttcatcgat ggattggtca cttaatttcc cataattttc
     3781 aaatttacgg gtacggtaat acacatcacc tgaagattca taagcatagc ctttttcaac
     3841 caacacttga ataaatgcta aaatatctgg catatgatcc atgactcttg gatgcagtgt
     3901 agcaggctcg acattcaacg ctttcgtatc ttcttcaaat gctcggatga aacgatcagc
     3961 aacttctggt gctgtaatac ctaattcgtt tgctgtacgg atgattttat cgtctacatc
     4021 cgtgaaattc gatacgaaat cgactttata gcctcgatat tcaaaatagc gtcgaattgt
     4081 atcgaaagca atggtgctac gagcatttcc gatatggata taattataca cagtcggtcc
     4141 gcagacatac ataccgacat gtcccttttg tatagggatg aattcttctt tttttctggt
     4201 caatgtattg tagattttta tcattctgat ctcctcactt tttctccttt gattcgaacg
     4261 acttttgctg gtactcctac cgctgtagcg tcgtctggaa catctttcaa cacaacggca
     4321 cctgcaccga ttttggcgtt ttttccgatc gttaccggtc ctaatatctg cgcattcgca
     4381 gagagcatgg ctccttgttt aacagttggg tgtcttttac ccgtttcttt tcctgtgccg
     4441 cctaatgtta cgccatggaa taaaatcaca tcgtcctcga tttctgcggt ttcgccaatg
     4501 acgattccca ttccatggtc gatgaacacg ccagttccaa tcgttgctcc tggatggatc
     4561 tcaacaccag ttaggaaacg ccagaattga gcattgatct tcgccaataa aaagagccgg
     4621 tgctgatata aaaaatgaga gaaacgatgc caaaacaagg catgaaaacc agggtatgtc
     4681 aaaacgatct cagctgtcga acgtgcagcc ggatcgtttc tctttgctgc atcaatcgct
     4741 cgggtaaacc aactcatgac tttccactcc tttcgtaaga attttatgta ggaaatcatc
     4801 ttcttataaa gaaaagaagc gccttttaaa taagtttcct tatcaaaaga cgctttccgc
     4861 gtggttccac ttttcttcat aatcaatgat tatctctgac agctaacgcc tgttatacgt
     4921 tcttggctac tttgtttcct ataaaacagt ttttcctgtt ttctgtgttt cgccaagacc
     4981 actcccagag gcatttcggc aaccattcat tgataccttg caccacccgg tatctctctt
     5041 gtaatgatca gctgcttact tttttctgtt catcgtgttt agttcagtac ttgatttaaa
     5101 tgtgctaatg atttttcacg accaagcaat tcgatcgttt caggcaattc tggaccatgc
     5161 atttgtcctg atacagctac acggattggc atgaaaagat tttttccttt tacgccagtt
     5221 tctttttgaa cagctttgat ggcagctttg acagttggag catctactac ttccatttgt
     5281 tctagctgtg ctttgaatgc gtggagaaca gtaggaactg tttcaccagc aagtacttct
     5341 tttgctgctt cattcaatac aggatgttca ttgaaaaata gcgtagacag atcaacgatt
     5401 tctgcagcat agctcatttg aggttgatac aggctaacga tcttcttcac ccattcgatt
     5461 gtcttttcat ctgggttttc tgctacacgt ccatcagcga ttagataagg cagacacatg
     5521 tcagtaaatg catctagatc cattgctttg atgtaatggt tgtttaccca ttgcagtttt
     5581 ttcgcatcga aagctgcggg tgatttactt aggcgttttg gatcgaacat tttgatcaat
     5641 tcttggtgtt cgaagatttc gtcttcgccc acaggtgacc agcccaataa tgcaataaag
     5701 ttgaacattg catctggtag atagcctaat tcgcgatatt gttcgataaa ttgcaagatt
     5761 gattcgtcac gtttgcttag ttttttacct gtttcactgt tgatgatcaa tgtcatatgt
     5821 ccgaaggttg gtggtgtcca gccaaatgct tcatagatca tcagttgttt tggtgtattg
     5881 gcaatatggt catctccacg taaaacgtga gtgattttca tcaaatgatc atcgaccgca
     5941 acagcaaaat tataagttgg cataccatcg cgtttttgta tgacaaagtc gccaccgata
     6001 ttatcggatt cgaacgaaat agcgcctttc accatatctg taaatgcgta ttctgtattg
     6061 cgaggcacac ggaaacgtac aacagattct agaccttgtg cttctttttc tgcttgttct
     6121 tcaggtgtca agttcgcaca tgttcctgcg taatgaggca tttctcctct tgcgcgttgt
     6181 gcttcccgtt ctgcttctaa ttcttcttct gtgcaatagc atttgtatgc tcgattgcta
     6241 gcaagcagct gatcaatcag cggttgatag atttctttac gttcagattg acggtaaggg
     6301 ccgtattctc caggattttc aggagattca tcccaattca ttcccaacca agcaaggttt
     6361 tccaactggc ttttttcgcc atcttcgata ttacgttttt ggtcagtatc ctcaatacga
     6421 ataataaagt ctccatcatt gtggcgggca aacaaataat tgaataatgc agttcttgca
     6481 tttccaatat gcaggtgccc agttggactt ggtgcatagc gtacgcgtac tttcgtcatt
     6541 ttcttcctct tctttcaaac tagactttga ctaacagcaa aaattccgtc agttacggct
     6601 tctcaaatat catttattta aagccactca gcacaaattt taccttttct aaggtaaata
     6661 gtaaagccaa ctggttgaat ttccttacca gttggctgaa tttctttttt attttgattg
     6721 tttagtcttt ttctctgtct cttttttatt gtcgattcct cgtcctgcat gtgcaggttt
     6781 agcaaagatc atgcgtccag cagctgtttg aagggcactt gttacaacga cttcgatacg
     6841 ttcattcatg taatgctgtc catcttctac gacaaccatc gtgccgtcat caaggtaggc
     6901 tactccttgt tggcgttctg tcccggcttt tactactaga acattcatcg tttcaccagg
     6961 gatgacgact ggttttacgg catttgccaa cgcattgata ttaagaacag gtacattttg
     7021 gaattcagag actttattca agttatagtc attggttaca atgacaccat ctaaaagctt
     7081 agccaatttg atcaatttgc tgtctacttc actgatatct tcaaagtctc catcgtacat
     7141 ttcgacagat ataccctctt ctttttgcaa ggcatttagg atatctaatc cgcgacgacc
     7201 acgcacacgt ttcaaactat cccctgagtc cgcgatgtat tgtagttcgt aaagaacaaa
     7261 attagggatc atcaaggttc cttctaagaa tccagtcttt gtaatatcat aaatccgacc
     7321 gtcaatgatc acgcttgtat ccaagatttt atatttatgg aaattttctc ctgattttcg
     7381 ttctaacagt tgactctcaa cttgactagc tgtttcttgc tcgatttttt tgcttcgtga
     7441 accaaaaact ttcttccatt cttcgattcg tgtcgttccc attctcaatc ccagatagcc
     7501 taagatgatc atcagtaaaa tcggcaatac actattgacg aatggaattt ccatattgta
     7561 aagaggggtc gagatcacaa cacctaaagt caatccgatg atcgcaccga tcgcaccgaa
     7621 gagaagataa gtcaagctga cctcacttag tttttgttct acttgtttga taatagctga
     7681 gatatgtttg gccaacagca aagataataa aaagaaaata agtgcgccta acaggctgtt
     7741 ggtaaatgta ttattcagcc atccgtttga ctgttgaccg attgcctgcc aagctgaggg
     7801 taaaaatgaa atacccaagc ttgcgccgac aatgatcatc agcaaagtaa tgacacgttt
     7861 ttgcatcgtt tttcctccgt ttcgacaatc atttattagt tagcggaaca cacgcttcaa
     7921 cgtttcagcc aaagttgcta ctccaactat ctcgattcct tttggcgctt cccagttacc
     7981 taagttgttt ttaggtaggt atacttttgt gaagccgagt ttttggactt ctttgactcg
     8041 ttgttcaata tgactgacac gtctgatttc tccagtcagt ccaatttcac cgatgaaaca
     8101 ttccgttggc tgtgttcctt tttctttata gcttgaagca atactgacag cgatagctaa
     8161 atcaatcgct ggttcattta attttacccc acctgcagct tttaagtaag catcttgatt
     8221 ctgaagaagc aacccagctc ttttttccag cactgccatg atcagagata cccgattgaa
     8281 atcaagacct gttgttgttc gtttggcatt tccgaacata gtaggtgtga ctaatgcttg
     8341 gatctctacc aaaattggac gtgtcccttc cattgccaca acgatagcag agccagttgc
     8401 accgtctagg cgttcttcta agaaaatctg tgaaggatta gcgacttctt ccaatccatg
     8461 ctcatgcatt tcaaaaatcc caatctcatt cgttgagcca aatcggtttt ttactgctcg
     8521 caaaatccga aaactatgat gttgttcacc ttcaaaatat aacaccgtat ccaccatatg
     8581 ttctaacatt cttgggccgg cgatcgagcc ttctttggta acatgaccga cgataaaaat
     8641 ggctatccca tttgttttag cgattttgag tagttctgca gtggtttctc ttacttggct
     8701 gacacttcct gccacacttg tgatgtctgg ctgcgtcatc gtttggatgg aatcaatgat
     8761 aacataatca ggggagatat gttcgatggc acgactgatt tcgttcatat ctgtttcagc
     8821 gtatagataa aattctgtgt tgatacttcc gaggcgttcc gcgcgtaatt ttatctgctc
     8881 tgcgctttct tcgccggata catataagac ttttccgcct atggctgcta attgctgaga
     8941 aacttgtaac agcaaagtgg atttcccgat acctggatcg ccaccaatca agaccataga
     9001 ccctggcacc acacctccgc ctaacacacg gttcagttct tctaattttg ttttgatccg
     9061 aggttctttt ttagggacga cgtctgcgat ttttgttggt tttgcttttt ctcctgtcaa
     9121 acttgtccga gttctgcggt ccgttgtatc ttgttcgatt tcttcgacca tcgtattcca
     9181 ttttccgcaa tttgggcagc gtcccaagaa cttaggcgac acatacccgc aattttggca
     9241 aacaaattgt acttttgatt tttttgccat tgtaccgcct ccttttatcc taatcatgag
     9301 acattaaatc aagcttaagt atctttaacg ttttatttac tggaagaacc aaatccgcct
     9361 tgacgttgag cagtcgtttg atcttgatct gcttttaaaa acggcaaaaa gatcccttgg
     9421 ccgatacgct cgcctttttt gatcactaca tccttgaaac caaagttggt gaattggaac
     9481 atgatatggc cttcatttgc ctcattattg taataatcac tgtcaatcac acctactccg
     9541 tttgtcaaca ctaaaaaccg cttcaacgga ttgcttgaac ggttagcaag ctgcaaaaat
     9601 tcatcttctc ccatgtaagc tttgattcca gtaggcacga gggttggttt caattgtttt
     9661 tcattttctg atacatcttt tttcaatcca tctgcgactg tttccaaccc ctttttccag
     9721 cctgctttcc agatacttgg aatcacgacc tcttctgctg cttcaaaatc atagccagca
     9781 gcatgatgtg tagcgcgctg cggtagattg atattttgat ctttatattt agaaataact
     9841 tcaaatcctc tttttctcac cggttttcct
//
LOCUS       DADGHT010000104         9551 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.105, whole genome shotgun sequence.
ACCESSION   DADGHT010000104 DADGHT010000000
VERSION     DADGHT010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9551
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.105"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..417
                     /locus_tag="JX887_002406"
                     /pseudo
     CDS             1..417
                     /locus_tag="JX887_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(325..1041)
                     /locus_tag="JX887_002407"
     CDS             complement(325..1041)
                     /locus_tag="JX887_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAX1258349.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(1091..1300)
                     /locus_tag="JX887_002408"
     CDS             complement(1091..1300)
                     /locus_tag="JX887_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258350.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            1577..2850
                     /locus_tag="JX887_002409"
                     /pseudo
     CDS             1577..2850
                     /locus_tag="JX887_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2957..3988)
                     /locus_tag="JX887_002410"
     CDS             complement(2957..3988)
                     /locus_tag="JX887_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1258351.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(3995..4825)
                     /locus_tag="JX887_002411"
     CDS             complement(3995..4825)
                     /locus_tag="JX887_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1258352.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(4822..5628)
                     /locus_tag="JX887_002412"
     CDS             complement(4822..5628)
                     /locus_tag="JX887_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1258353.1"
                     /translation="MKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLANYS
                     DIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLAANF
                     AGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYPSMK
                     EVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALTSSN
                     VNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(5634..6458)
                     /locus_tag="JX887_002413"
     CDS             complement(5634..6458)
                     /locus_tag="JX887_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphatase"
                     /protein_id="HAX1258354.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(6448..7548)
                     /locus_tag="JX887_002414"
     CDS             complement(6448..7548)
                     /locus_tag="JX887_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAX1258355.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            7726..8511
                     /locus_tag="JX887_002415"
     CDS             7726..8511
                     /locus_tag="JX887_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HAX1258356.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            8544..8927
                     /locus_tag="JX887_002416"
     CDS             8544..8927
                     /locus_tag="JX887_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAX1258357.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            9003..9134
                     /locus_tag="JX887_002417"
     CDS             9003..9134
                     /locus_tag="JX887_002417"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1258358.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            9103..9339
                     /locus_tag="JX887_002418"
     CDS             9103..9339
                     /locus_tag="JX887_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1258359.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            9351..9518
                     /locus_tag="JX887_002419"
     CDS             9351..9518
                     /locus_tag="JX887_002419"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258360.1"
                     /translation="MELGGLPELDGRYTVFGQVYQGLEIVAAIAAQPTNSEDVPIEPV
                     FIRQINFEKTS"
BASE COUNT         2796 a         2267 c         1850 g         2638 t
ORIGIN      
        1 gttccatgag ttttatttgt gttgatggga caacccatca gctatttacg atccttgaag
       61 atcgcagact ttacaaacta actcaatact tcctgcactt tcctagaaaa gcccgtttaa
      121 aggtcaagta cctagaatgc cagctattgt cagctgctta aaacggtctt tccaaatgcg
      181 gagatcgtaa ctgatcgctt tcatattgtc caacatatca atcgcagctt caatcaattg
      241 cgtatccaga tcatgaatcg ttttcgagcc tcgcactctg aaaatcagaa gaagtaccgt
      301 cggctcaagc gatattggaa actcttactc aaagattcca cgacattgga gccgctcaaa
      361 cggcattatc atcgactgtt taaacgacca attagtcaaa cagaaatcgt cgatgaaccg
      421 ttgtgcacaa tggtgtcctg aacgtacagc gacaccttcc atatccagag cagtcgccac
      481 atcacgggga tggatgccat ccaaattaaa agcaaccacg ccagtatgat gttcaggatc
      541 ttgcggtccg taaatggtga taccgccgat cgcttgtaat ttaggtaaaa cgtaggcaac
      601 cagttcttgc tcataacgat gaatattctc cataccaatc tcattcaagt aatcgattgc
      661 tcctgcaatg ttcggagtac cagcttcaaa tttccatggc agctctttcc atgaactatc
      721 gtaaagattg acaaaatcta tcatttcacc gccgaattcg actggctcca tttgttctaa
      781 caattgacgt ttgccatata atacaccgat tcctgtcggc ccgcacattt tatgcccgct
      841 aaaggcgaaa aaatctgcat ccaacgcttg tacatcaact gtcatatgcg gtgctgcttg
      901 ggcaccgact ggactatcct caactacaac agcctgttca accctcagcc gtttcaagca
      961 caacaaataa ccttctggat ctggtttgcc gacctgaaga tcatcgatcg tcacaaagga
     1021 atcaattttt tccttaatca tcggatgtgc ttcaaaaaaa tagtctagct cccgcagttc
     1081 agaattgaga ctactccgat tttccagtgc tgctgatccg ctgctcaaaa tgttcagcat
     1141 ccactggtct cccaaccgct tgacttatcc cttcataaaa ggacagttct gctgccgtcc
     1201 caacaccttg ttgatagtct gcaaaaggaa ttttatagcc gaactgctcc agtaaatagg
     1261 cttcagtaaa tagtgatgaa tactctcgta aaacatccat tcactgtcaa tcatcgtccc
     1321 atcaaaatca aaaataagtg ctttggtcat cttctttccc ccttacccaa aacaagcaaa
     1381 agctgtgtcc tgctctctct acagtatcag cataaaaact gccgtctgaa aagtcaaagg
     1441 tgaaagaaat gtggcgctat aatttctagg actgatagta aatcattcta tcagtccttt
     1501 tgagcataaa aaaacaaaac atacagaagc tccgttagaa ttgaatcacc acaacacaat
     1561 caaaggagcg ttctgtatgc ctgatcttca tcttatcaaa ctattactag gaatcaaaga
     1621 tggaaacatt caaatcactc atgtcgagaa gaaaaaaata cattcaatca acagtatcgt
     1681 tgtttctgcc acgctcatta aaacgattca gccctgtcct cagtgtaaac aggtgaatca
     1741 acatgggctg atcgttaaga acggaaagaa aaaatcgctg gtccttctca ataagtgtgc
     1801 gaatcaacgg acttatcttg ctttggcaaa gcaacggtac ctctgtcgtg gctgtcacac
     1861 ctattttacg gcgaatacct acattgttga aaaaaactgt tttatcgcca aacaagtaca
     1921 ttataaaata ttggaggaat tgactgaaaa acaagcaatg acgacgattt ctaaacattg
     1981 cggcgtttct tggtcaaccg tttcgcgaac actcgcttct ctgctcccca tgacaaacgt
     2041 gaaaataaat tggttgcctc gctgttcatt ggtagatgaa tttcgttcat tgaaaaatca
     2101 agtcggtccc tattcttttt cttgtatgga tggcgatact gggaaattac tggatattct
     2161 tccttcacgt aagaagaaag atctcatttc ttattttatg caatttgaac gacgtgcacg
     2221 tttaaacgta aaaatactcg taacagatat gaacgcctct tatgctttgc tgataaaaga
     2281 gtgctttcct catgccaaac tcgttgtgga tcgctttcac atcgtcaagc acctcattcg
     2341 cagttttaag gatatttgac tatgagtcat gaaaagcttc gaccgaaacg atccaataca
     2401 agccaaacac tatcgacaag tgaaggcttt atctcgactt ctgatcaaac gacaggacac
     2461 gcttgtttat gataaatgga caaaatggcg taattttggt tgggcctatt taaccgaaag
     2521 tgaagtcgta gaacgtctac tttctacttc tgatgaacta cgaatagctt atgcttacta
     2581 tcaagaaatt cttcaagctt tttatgacaa agaagcggac atcttctttc agcttgtaaa
     2641 aacaatgccc aagtcggttc caagagaact gcatcatata aaaaaagcgt ttataaacta
     2701 tgaatccggc attcgtttag ccttagagtt gccttactca aatggcaaaa tagaaaatct
     2761 gcatacccac atcaaagcat tgaaacgaat agcttacggg ttaggatgag aaccagaatt
     2821 ttcttaatca atcatctgat cacttattaa acataaaaaa acatctaaag cagaaaatca
     2881 attctacctt agatgttctt atatcactct atcagtccta tttgacaaag agccagaaat
     2941 gtttgccgac tatacactag ctttgttgtg caaaatgctg agtatcaatt tccacaggga
     3001 ttgctagaat atctttcagc tgaatgtata aggcatcgct aattttctct tcccgatcgt
     3061 tcaaccgatc cactaaaatt tctttgccct ccagcgtttg aaaaacatac cgttgaatgt
     3121 tgcctaaaat aaatgattcc ttccatagaa ccggaatctt aaccccctga ggaaccggtt
     3181 caaattgaat cagctccggt cttaaataat aaatgcagcg attgccctta gcggaaaact
     3241 cgtgggtata ctgattcagc tcataccatt cgaaacgatt atagttgccg ataaattccg
     3301 caacaaatcg gctctgagga ttctgataca attccttcga ggtggaaacc tgagccaccc
     3361 gcccagcttc catcacaaaa atccgatcac tgattcgcat cgcctcttct tggtcatgag
     3421 tcacaaaaat catcgtcatc cctagcgatt gctggatagc gcgcaaatcc cgctgcagct
     3481 gttttctaat tcgggcatcc aaagcactta atggctcatc cagcagcagg actttcggtt
     3541 cagtgaccaa tgagcgagcc agtgccaccc gttgtcgttg accgccagaa agaaactgga
     3601 catttttatc tgcctgctcc gtcatatcca ccaatgatag catctcaaaa accttttcct
     3661 gaatcacctc aggactcagc ttctttacct tcaaaccaaa ggctacattt tcaaaaacag
     3721 tcatagttgg aaacaatgca tactgttgaa aaacaaagcc gatattgcga tccttcgtag
     3781 gcttatcggc aatattctca ttgtccagca caatctcacc gctctttggt tgttccaatc
     3841 ccgtgataca gcgcagcaac gtagactttc cgcacccgct gggacctagt aaagtaacca
     3901 gctcaccctt ttcaatctga atttcatcaa tagctaaaat ctgtttttca tcaaaaaaca
     3961 gattgagatc atgtatttct aaaaacattt tccgtcacaa ctcctttaag ggcttctttt
     4021 tcgactgctt ctcttccctc gtctgcttaa gggacagctg ttgcttttgt cgataagtca
     4081 gcataaaggt agttaaagca attcccacca taaacagcaa atacaaaacc atcacagcgc
     4141 tagccaaatg gccgttttcg ttcatccgcc gcagcatata gatgcgtacc gtctgaaatc
     4201 gaccgccaat caacaggttc gtcagcatgt actccccaaa aaccgaagaa aaaatcatca
     4261 gagaaactag ggtcacaccg atacggatgt ttggaaacag cacctggata ataatcgtag
     4321 acatcggggc gcccaaggtt tctgctgcat ccactaattc cttcagatta attaagcgca
     4381 tctggttgtt aagactaaga tagacaatcg gcaacgccgt aataaacaat gcacctacca
     4441 acactacaaa cattgggata ccagtttcag catacgttcg aagcaaagcc gttaccaaaa
     4501 tcactcctgg taaagcatac ggcagcagga gcagcttttc cagccaacga ttcaaacgag
     4561 ggaaatacaa atgaatccaa ataatggtgg gaatcatcaa caacagaatc gtcaccaaga
     4621 ccacacctgc taataaaagt gagcgaccca ccgcagcaat aaattccctg tccgtcagca
     4681 gctgttggaa ccattgcaag gtaaaatcac taggtaaaag cgattttgac catttagtgg
     4741 agctggcata caaaatcgtt ccaataatcg gcagcaagta atacaggaca aagcagaaca
     4801 aaatcggttt tattaacttt ttcacgtctg caccaccttg cctttctttt gaataatcaa
     4861 cattgccgtt accagcagga cacctaaagc gactgccaac gcactgccta aattaggctt
     4921 ggcgaacaca tctcccgaca ctaaagccgc aattcgaatc gttaaaagat ttacattact
     4981 gctggtcagg gcatacgctg tttcataggt ccccatgcca ttagcaaata agatgacaaa
     5041 ggtgctggca atcgatggtc gcaaaaaagg caaagccacc ttgaaccaag catacgctga
     5101 tgaagcgccc agcaattgtg cggactccag ccattccttt ttcacttcct tcatgctggg
     5161 atacaaaaac aagaccccta acggaatttg gaaataggta tacgtgatgg tcaatcccca
     5221 ccaagaatac aaattgaagt ccgctagaaa tggcaaaatc attttcagca cacctacatt
     5281 ccccaacaaa ataataaaag agaatgccag cggaatccca gcaaaattag ctgccaaatt
     5341 ggaaacaaag gtgattttct cctgcaattt agtcgataga ttcattaagc ataaacataa
     5401 aataaacgtc ccgattaacc caatcacact ggagctgaca gcaatcagta cgctgttaac
     5461 aaaggcctgt gtgtaatatt tgttgctgaa aatatcactg taattggcca atgtccactg
     5521 gttagttaaa tcactgtgca agctgcacag aaccataaaa agcagcggca gcagtaaaaa
     5581 tgcacagaag ataaaggagg caggaaccag aaccaagcgt tttttcatct ctttcatccc
     5641 ctcatcaatt cttgaatgtc ctgcattttc tctgacggtg caattcctaa taaccagcaa
     5701 aacaatggag ccgccagcag ctgtggtaca gtttgttcct tcagcttttg gcgtttattt
     5761 gaaatcaaat aaaaaggaac ttcacgatgt gcagccaagc tgccgccatg cagtccgtgc
     5821 gcatccatcc cgtgatccgc agtcaccacg acttgataac ctttttgcag ccattcagga
     5881 aggtaaatag ccaataatct gtccgcctga ttaaccgctg ctgcatattc atgagaatcg
     5941 gcggtaaatt tgtgaccgac atcatcaata ttcatcgaat gtacgaccaa aaagtctggc
     6001 tgatactgat tcactaaata atgggcatcc gcaaataaat gcgaatcagg gtaagtgtcc
     6061 tcactataaa agatgccatg ctgaatcagt cgctcctcct gatgctggat gcgatcaacc
     6121 aaacgattat agggggcttg attgtacaac tcgctgtacc agtggtaagc ggcggctcct
     6181 gtttttccgc cagcttcctt aactaattca aacagcgacc actctttgga tcgctgagca
     6241 tggtaattac tatagatgcc attttcatag gctggaacgc cggtcatcag tacttcgtat
     6301 aacggacgtg aattgctggg cagctcactt tttaccttca ataagcttgc ttgctggtgc
     6361 tcaactaaat gattcatgaa cccaagctgg gcgacggctg tgtcgtagcg acagccgtct
     6421 agtataacta caatcagttt gtcaagtcta ctttgcatag gtcagtacct ccgcctgcca
     6481 aagctctgga agctctacag aggtcttgtt ccaagcttca ttgtcttcaa ctggcaccgc
     6541 cgcttcataa gcatcctccg gcagtaattt ttcagctact tctttaggca gctctacctt
     6601 gcgaataggt cgcgcatagc cctttgccaa attgatttgc ccttcatcag ataaaatata
     6661 ttcccgtgct agctttgccg cattgggatg aggggcattt ttattgatta aggttgtata
     6721 cccgctaatg atggagccgt ctgttggcac agttacctca aaacgctcgg agtcaatttg
     6781 gtcacgataa tttagtccat tgaagtccca aacaactgcc acatcgattt cacctttttc
     6841 aagatttgct acgctggcat caacggtgga caaacggcct ttttctgcca tttttttgta
     6901 gtaattcaga cctggctgaa tatccttttc gtcacctccg ttggcaatcg ccgcagccaa
     6961 tacagcaaat tgtgcttggt tggcaatcgt cacatccccc acgctaactt gatagtcacc
     7021 ctcttgcagc tccttccagc tagtcggtgc ttgcttcaca ttctctttat cggtgataaa
     7081 ggaaatggtt cccgtatagc ttaacaacca atccccatca tcatcctttg cccaatccgg
     7141 aatttcctcc caatagttgg tcttataagg taaggttaac tctttgcttt cagccaacgg
     7201 accgaagctg ataccgacat caccaatatc ggcggttcca ttttttcctt ctgattcaaa
     7261 cttagccaat tcttctgcac tggacatatc cgtatccacg tgacttaagc cgtattcttt
     7321 ttcaaggtcg ttccaagtgc ctacccaatt tgcccaagta tccggcattc ccaagctggc
     7381 aatctctcct tcttccttgg ctttttctat aatcgtatct aaagagtcgt ctgccgcagc
     7441 cgattgcttc gttgcttcac ctgagccgca gcctgtcagc aggatactta ctgttgctgc
     7501 acaaaataaa ccgatagtca tgttacgaat tttttcattc attttcattc attcttctcc
     7561 cctttcgata attccattct aacaaagctt tgtaatgaga gaatcagttt cttgaaaagg
     7621 tttcatgaac aatgtaaagg ttgtatatgg tttgtaaatt tcgacgaatt cccgttaacc
     7681 ttctaaagct tttgcggtat gatagtagaa aaaaggaggc tccctatgca gtattatgat
     7741 cagcatctcc acacgtattt ttcctttgat tcagaggaaa aatttgaaaa ctatttagcc
     7801 tatcagccgg agtttttcgt ttctacggat cactttgatt taaacaatcc atctaccgga
     7861 aaagatgaca ttccggatta tccagcctat ataaacaaac tggactcttt aaaagaaacc
     7921 tattccacca aatttctgcg aggtatcgag attggcgttg ttccaggaca agaagagcgg
     7981 atcgtggatt acctcgctca gcatccttat gatttaaagc tggtaagtat tcatcaaaat
     8041 ggccgctttg attatatgga cgatgtggtt ttaaccaaag atcccattca aactaccaag
     8101 gaatattttg atcagatgtt gcaggtcttg acggattttc cagaaggaga tattttgact
     8161 cactttgatt atggattacg ccgcttcacc ttcacagcgg aagaattcgc ggagcatttt
     8221 gaggctcagc tgctaacgat tttcaaaaag gttgttgaac gagaattggc gatggagtta
     8281 aatgccaaga gcttcttgaa atacggcaac gaagaccttt accgttatgc cgttcctttg
     8341 tatcaaagtg tcggcggaaa gctctttacc ttaggctcgg atgctcatgt tgccgaagat
     8401 tatcagctgg gctttaaaaa aatgagtcag ctgttggcag actgtcaggt agaaaagttg
     8461 ctagtcattc aaggaaaaga acgccgcctg acgccgctgc cgattttgtg attcctatat
     8521 aatagaagaa agtggtgaaa aaaatgagca acctgtggga ctacaatcaa gaggcaccca
     8581 tccattattt aattgcgcga cattgggatg cgttgaaaat tgaggcggtt tgccgatcct
     8641 tgttagcagc cgttccaaaa caacaactgg aaaatttttt ggtggctgac agcttgcagc
     8701 gggaaaaagt tcaggcttat tttgcagcct ttaaagatca gcctttggaa tatttgcatg
     8761 cgcagtttca tcttttttat caagtagccg ccccagatga ctacaacgat ttacgaggac
     8821 agctgcaatt gacctttcaa gcggatgaaa ccgcctatac cgttttattg ggaatggctc
     8881 gccttggtga tcaggcgaag gtcgagtggc ggattttcga tatttgatgg caggatcaag
     8941 gcgtttcagt tgcaaacctt cctctctttc aattagaaaa accgcagcag gaagaagttt
     9001 gtgtgctggt caccgatgct ggtgaaattc gtctccgctt atttcctgac caagctcccc
     9061 tggctgtagc caactggcgc tccctagctg agcaaggcgt ttatgacaac acacctttcg
     9121 gctcgtgtca ttaaggaatt tgttattcaa ggtggcgctt tggatggttc tggtgatgaa
     9181 gctgtttcca gctatgaggg ctttttcgct gatgaagtgc atcgcggact ttatcatttt
     9241 aatggcgcct tggccttagg ggaccacggc ccccacacca acggcaacca gttttttatt
     9301 gtgcaaaaca caaaggcgca ggctgacctg ctaatgtaaa gcaagcatac ttggagcttg
     9361 gaggactacc ggagctggat ggtcgttata ctgtttttgg acaggtatac caagggttag
     9421 aaatcgtagc agcgatcgca gctcagccga caaacagtga agatgtaccg attgagccag
     9481 tgttcattcg acaaattaac ttcgaaaaaa catcgtaaaa agacactcac tgacttcagc
     9541 aaaagctcta t
//
LOCUS       DADGHT010000105         9513 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.106, whole genome shotgun sequence.
ACCESSION   DADGHT010000105 DADGHT010000000
VERSION     DADGHT010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.106"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(310..2436)
                     /gene="pnp"
                     /locus_tag="JX887_002420"
     CDS             complement(310..2436)
                     /gene="pnp"
                     /locus_tag="JX887_002420"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAX1258361.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(2624..2893)
                     /gene="rpsO"
                     /locus_tag="JX887_002421"
     CDS             complement(2624..2893)
                     /gene="rpsO"
                     /locus_tag="JX887_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAX1258362.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            3144..3707
                     /locus_tag="JX887_002422"
     CDS             3144..3707
                     /locus_tag="JX887_002422"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAX1258363.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(3960..4481)
                     /locus_tag="JX887_002423"
     CDS             complement(3960..4481)
                     /locus_tag="JX887_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAX1258364.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(4484..5326)
                     /locus_tag="JX887_002424"
     CDS             complement(4484..5326)
                     /locus_tag="JX887_002424"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAX1258365.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(5319..6044)
                     /locus_tag="JX887_002425"
     CDS             complement(5319..6044)
                     /locus_tag="JX887_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAX1258366.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            6220..6516
                     /locus_tag="JX887_002426"
     CDS             6220..6516
                     /locus_tag="JX887_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258367.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            7084..8676
                     /locus_tag="JX887_002427"
     CDS             7084..8676
                     /locus_tag="JX887_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAX1258368.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            8689..9429
                     /locus_tag="JX887_002428"
     CDS             8689..9429
                     /locus_tag="JX887_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAX1258369.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         2653 a         1928 c         1885 g         3047 t
ORIGIN      
        1 aacggaaaaa tagttcctca tattttgccg ttttttgagc taatatcgag ggacagctga
       61 ttgaacatcg tttattggag aggttgtaaa aaagctgttc tgcatcaagt aataagaaca
      121 gccaagtaaa aacagctcct aatgttttta acttggctgg acttattacc gcagatgcaa
      181 gcttttgaac accgtttatt cgaaaaaaaa ggactgtgac acggcttttg tcacagtccc
      241 cttttttcga ataattattg tccccctgtc accttcacga tcacaagtac attattccta
      301 tgaattaaat tatttttctt catttttcgt tgaaccatct tcgttcaaca ttgcttttct
      361 tgacagattt acgcgtcctt gtttatcgat ttcagttact ttcacaagga tctcatcacc
      421 tagtttaaca acatcttcga ctttattgac acgatcgttt gctaattggg aaatatggac
      481 aagtccatct tttcctttga tcaagttgac gaatgcaccg aatttttcga tacggacaac
      541 tttccctaga taaacttcac caactttgac ttctttggtc aaatcttcga tgatcttgat
      601 agcttttttg atcatttctg catcagctga agcaatactt acttttccat cttgatcgat
      661 atcgattttc acaccagttt catcgatgat tccgttgatc gtatcgccgc ctttaccgat
      721 aacatctttg attttagcag gttcgatctg gatcatttcg atttttggtg catattggct
      781 taattcttca cgtggagcag caatcgttga agtcaattct tctaagattt ccatacgtgc
      841 ttgttttgct tgagttaatg cttcagttag gatttgttct gtgattcctt gaatcttgat
      901 atccatctgt aaagcagtga taccatcttt tgtaccggca actttaaagt ccatatcgcc
      961 aagatgatct tccagccctt ggatatcagt taggatcgta tagttttcac catcagaaac
     1021 aagtcccatc gcaataccgg cgactggcgc tttgattggt acacctgcat ccatcaatgc
     1081 taatgtgcca gcacagatac ttgcttggga agaagaacca tttgattcca atacttctgc
     1141 tactaaacgg atcgtataag gaaattcttc ttctgaaggg attacttgtg ctaacgcacg
     1201 ttcacctaat gcgccatgtc cgatttcccg acgccctgga gagcctgcac gtcctgtaga
     1261 accaacagaa aattgaggga aattgtagtg gtggatgaat cgtttgctga cttccacccc
     1321 taaaccatca atgatttggt gctctcctag aggtgcgagt gtacaagctg ataaagcttg
     1381 tgtttgtcct cgtgtgaaca aacctgatcc atgtacacgt ggcaataagc tgacctctga
     1441 tgacaatgga cggatttcat ccaatttacg cccgtcagga cggatcttat cgatggtgat
     1501 caattcacgt acgacatctt tttcaagatc ttctgtgatt tgtttaactt ctttcaacaa
     1561 gtgatcttca tcttcatgac ctgcaaattt ctcagcataa gcttcgcgga tatcgatctt
     1621 cacctgctcg atattatctt cgcgagcaag tttttcttca gtcattactg ctgctttcat
     1681 tgtagcgtaa gaagcatcaa agatttcttt tttcaatact tcatcaactt gcagtaaagt
     1741 cacttccatt ttttctttcc ctactgcttg aacgatttct tcttggaaag caactaactc
     1801 tttgatagcg tcaaaaccaa acagcaatgc accaagcatg tcttcttctg aaacttcttt
     1861 cgcgccgctt tcaaccatat tgatggcttg tttcgttccg gcaacagtca attcgatatc
     1921 tgtttgttct gcttgttcta ctgttggatt caagacgtac tcgccattta cacgaccaac
     1981 ttctacgcct gcgattgggc cgtcaaatgg gatatctgag attgatagtg ctaaagaaga
     2041 acctagcatt gctgccatag ctggcgagca gtctgtttct acactcatca cgatgttcgt
     2101 tacttggact tcattacgga agccttctgc aaacatcggg cgaattggac ggtcgatcaa
     2161 acgggcagtc aatgttgctt ccgtacttgg acggccttct cgtttgatga aacctccagg
     2221 gattttccct gctgcataca ttttttcttc ataattgatc gttaatggga aaaagtctgt
     2281 atcttttgct tctttagagg ccacagctgc acttaagact actgtatctc cataacggac
     2341 taaaacggct ccgtttgctt gttttgctag ctgaccgact tcgatttgta agggacggcc
     2401 gccccatgtc gttttgaata cttgtttttc tgacataact tctccttttc cttctcgtga
     2461 aagcaagacg ctactaaaca aatgaaaact gccgaaagcc gtcttttgag cagctttcat
     2521 ttggttagta ggagtccatc tagcttgatc acggaatttt acttaattga tatacgagta
     2581 aaaaaagtga gattcatgtg aatcccactc tttttgacta aaattaacga cgcaagccta
     2641 aacgtttgat caattcgcgg taacgttgaa cgtcagtttt acgtaagtaa gctaacaagt
     2701 tacggcggtg accaactttt ttcattaggc cgcggtatga atgatggtct tttttgtgca
     2761 cgcgtgcatg ttcattcaag tggttgattt cttcagttaa tacagcgatt tgtacttctg
     2821 gagaaccagt atccccttca tggcgagcgt attcgttgat gatttcattc ttgcgttctt
     2881 ttgaaattgc catttctttc acctctttcg attattcccc tgcgactgag taaaacgttg
     2941 gtgattcgct taaccaagtg gcaggtcatg tgcctagagc acacagctat actttacctg
     3001 aaaccgggtt gaaaatcaag tagttaatca ttaagaaaag gtagttttca aacaatctta
     3061 ctactacttt tccatttttg tggtaaacta taatgcgaaa atagacttga aacacagtct
     3121 tttaagaaag gggtacatat tccatgatta caatggatga tatcattcgt gaaggaaatc
     3181 cgaccttacg cgaagttgca aaagaagttt ctcttccatt aagcgaagaa gatatctctt
     3241 taggaaaaga gatgcttgag ttcttaaaaa acagccaaga tccaatcaaa gctgaagaac
     3301 tacacttacg aggcggtgtt ggcttagctg ctcctcaatt agatatttct aaaagaatca
     3361 ttgctgttca cgtaccaagt cctgacccag aggcagatgg accttctcta agtactgtta
     3421 tgtataatcc taaaattttg agccattctg ttcaagatgc ttgtttaggg gaaggtgaag
     3481 gctgtttatc tgttgatcga gaagtaccag gatatgttgt tcgccatgcc aaaatcactg
     3541 tgtcttatta tgatatgaat ggtgaaaaac acaagattcg tttgaagaat tatgaatcga
     3601 tcgtcgttca acatgaaatc gaccatatca acggtgtgat gttctatgac cacatcaacg
     3661 atcaaaatcc atttgcacta aaagaaggcg tattggtgat cgagtagaga attggcaggt
     3721 tccttcgata ctatgctaca agaaagcttt ataaaaaagg ggagtgctca aaagctgcac
     3781 ttcccttttt tatgtttctc cactaatcga aatttagata gacatctaga aatcgcaatt
     3841 ccaaaaaatt ctgtgtattg gatacgcatc ttttcttatt ttttcttatt tcttccatat
     3901 gggtgtttat ctcagagatg atagaatagt ttctaggata aaaagtagca gctacgatgt
     3961 tatccttcgt agaggattcc tgcttcagct agtttttgtt tgatgttttt cagcatatgc
     4021 ttttctgggt agcggatcgt atgcagatgg atgccgcctg ttaattcgga taacaaagta
     4081 gcattacttt tttgataacg tctcataaag gaatcgatat cttgtggcgt tttgatgtgc
     4141 aaagttcctg ctaactcacc gtaaagggga tgttccacaa ttacatcaat gatttcacca
     4201 ccattttcaa cgattagtct cagttcttct tctgtttgat cttttccatg ctggacagcg
     4261 attttactga tgtgcccagt attggtttct tctgtttcga ggatataacc tcttgctgtt
     4321 gccacgatac ttttacctgc agctcgtagt aaagcaatat cgcctacaat gatctgacgg
     4381 ctgactccaa aagttttcgc aaacttgcta gcactcactg gtttttctgt atttgccaag
     4441 gtttgcatga tttgttttcg ccgtgtctct ccttcgatca cacttattcc tccttcattt
     4501 tgttttggta ttcgcgcgag tgtttcatca aatcaacata cgtgtctgtt attgtttcct
     4561 tatatccctt atttttcagc agactaacaa ctttatccaa tacttgctgc tctctttttg
     4621 catcataaac tgcttggttt tcttcttttt tcacttgtcc tattttagtt accgtatcca
     4681 ttcttttttc taataaagca accaactctc gatcgatcat atcgatctta tgacgtaatg
     4741 tttcaagaga ctcttctgtt agttcttcct ctactgtctt gatgatacga gcaggatttc
     4801 ctgcaatcac tacattgtcg ggaaaagatt tggtcacaac cgaacctgcg ccgactacta
     4861 cgttgtcccc tagagtgaca cccggcgtga cgataactcc tccgcctaac caaacattat
     4921 taccgatttt aatgggtttt gcgtactcca gaccgctgtt acgtttcact ggatgtagtg
     4981 gatgcgtcgc cgtgtaaagc tggacattcg gagcgaacat gcagttatca ccgatttcaa
     5041 tcgtgctgac atctaaaaat gtacaattga aatttgcata aaaattctcc ccaacaaata
     5101 tattatatcc gtaatcaaaa ttgataactg gctccatata gatttttttc cctgtacggc
     5161 caaaagtctc tttcaacaat tgggatcgca gttccgctga ttctgcttgg ttgatgattt
     5221 ggctttgact tcttgcaaac atacggtcgg caaccagctc aggatcattg gcaaaataaa
     5281 gctcgcctgc aatcattttt tctttttcgg ttttgaattc agtcataatc tgctcctaat
     5341 tcttgtattt ttttgaaaac aaccgctccg tcttcttgaa taaacgtata aggctccgct
     5401 aaataaacag gcgtttgatt gattactaag attttggctg acggctggcg aaactgtacc
     5461 agatcacaaa acggatgaac ttgaaaactc gttccaacaa tgacgatcag ctctgcttgg
     5521 ctgacggcat aagccgcctg ctccatgact ccatcttgaa acccttcacc atataacacg
     5581 atgtctgggc gtatttgtcc tccgcatgct tgatgtttgt cgctgtgaag atattctttc
     5641 cagtctaccg tttgttgaca ttttcgacaa tgacattgat acagactccc atgaaaattg
     5701 acgagttgcg ggcttttagc ctttgcgtgc aaaccgtcga tgttttggga aacaacccaa
     5761 acattttttt ctttcgctag atgtgctatt tccaaatgaa tgatattggg ttttgcttca
     5821 ggatgataaa tctttttgac aaattgatag aatttatccg gttcattcac cattgcttga
     5881 tgactcagca agtattccgg ctgctccatc ccgtggtaga ttcctgacaa agatcgatag
     5941 tctggcactc cagaaggtgt ggatacccct gcaccggtca aaaatgtaat ttgctgataa
     6001 gctaatatct cttttgctgc ttcgtctact gttaattgtt tcatgttttg tcacctcact
     6061 ttccattata gcccatactc gaacaaattt attgttgaaa agtcagaaaa atgggaataa
     6121 aaaagtgtta tgggcatttg agcaatttat cacaatgttc actgacaaaa gaatgaaaac
     6181 gtgttacaat actgctgtat aaaagtgagg tgaatcgata tgttaccatt ctttatttat
     6241 tggggcgtta ttctggcttg tatcgcctgg ttagcgttaa gcgtttattt ctctgttttt
     6301 tatcttgtac gcaaagaaaa tggaaatctt tgggcttttg ctttattcaa cgtgattgcc
     6361 gcaattgttt tagccattac attagccgta tatcgaacat ggggctgggg aatcacccaa
     6421 tactcaagtt tgatttatct aatattagcc atttatggcg tcgttgttct tttgcaagcg
     6481 atcctaggac gtgagccaaa gaaagcggca gcttaaatga tcgagatgga actggacaca
     6541 ggaaattttc tgttctagtt ctttttttat tgtattacat acatttttgt gtataattat
     6601 actatcgttt gcaatggata gatgattcac attttgattg ttttttcggt aaaagtaaag
     6661 atttctatat ttatcagtat tttttcaaaa accagcagtt atagattgac aaagcctctc
     6721 gagtatcgta aacttttttt gtataaataa ctgaatacga gatgcctcaa tcaatgaggt
     6781 agaggtcgcg agaatcatta accctgtgga gtgaagcaaa catggagaag caggaatagg
     6841 gaggatcgcc gaaatgtgca cttttttgct tggagtgtat gttgggacgc aagttaagag
     6901 cttgcggact gtcttagcag tgatgctaag ttgcgctatg ttttgtgaga ggtttatcac
     6961 cttatggaat tttagcggcc tttttatatc tataaatcgg tcgcttttta ttttttcaga
     7021 taaagcttta ccgcatttca tctagaccgc tcgtgtatca tataatcaga aagggagaaa
     7081 aaaatgaaaa aaaatatggt ttcagttgcc gtactatttg cttttgtctt ctcactattc
     7141 agtgtgggat ctctggcaaa tgcagatgaa aaaacaccga gcgatgagtt tcgcgtaggt
     7201 atggaggctg ggtatgcacc cttcaactgg tctcaacaaa cagatgagaa taatgccttg
     7261 ccaattcaag gccaaaatag ttacgccggc ggttatgatg ttcaaatcgc taaaaaagta
     7321 gcagatggtt tagggaaaaa attagtcatc gtccaaacga aatgggatgg tctggctcct
     7381 gcccttcaat caggcaagat cgacgcgatc atcgccggaa tgagccctac tgctgaacga
     7441 cgaaaagaaa ttgattttac cgatccttat tacgaatcac aattagtagt agtagttcaa
     7501 aaagatagca aatatgcaaa agcaaaaagt ttagcagatc tttctggagc aaagatcact
     7561 gctcagttaa atacattcca ctatactgtg atcgatcaga taccagatgt gcagaaacaa
     7621 caagcaatgg ataatttctc agcaatgaga acagctttag cttctggaat gatcgatggt
     7681 tatgtcagcg aacgtccgga aggtgtaacg gcaactagtg tgaacaaaga cttggaaatg
     7741 cttgaattca gcggtgcaga tggcttccag acaaacccgg aagatgttca gatttctgtt
     7801 ggtatgcgta aaggcgaccc ggatatccaa aaagtaaacc agattctttc tggcatctct
     7861 aacgatgaac gaaccaaaat tatggaccaa gcagtcaaag atcagcctgc tgcaactgat
     7921 agtgaagaaa aacctggcat catttctgat ttcactacga tttggaaaca atacggcaat
     7981 atgttcttac gaggtgctgg acttaccttg ttcatcgcat tgatcgggac agttgtcggt
     8041 actacacttg gattactgat tggtgtcttc cgttcggtac ctgaatcagg aaatgcactg
     8101 actcgcttct tccaaaaaat cggaaatgca cttctttcta tctatgtcga agtattccgc
     8161 ggaacaccga tgatggtaca agcaatggtc atcttctacg gtctggcact cgcttttggc
     8221 atttcattga accgaacgat tgccgctttg tttattgtct ctctcaatac tggagcttac
     8281 atgacagaga tcgttcgtgg ggggattttt gcagtagatg aagggcagtt cgaagctgcg
     8341 caagccattg gtatgaccca tggccaaacg atgagaaaag ttgttattcc acaagtttta
     8401 cggaatatct tgccagcaac aggaaatgag tttgttatca atatcaaaga tacagcagtt
     8461 ttaagtgtaa tcggcgtagc tgatttgttc ttccaaggaa actctgcttc cggtgcgaat
     8521 ttccaattct tccaaacatt tacgatcgtc gggatcatct acttagtcat gacctttacg
     8581 atcaccagaa tcctgcgggc ggtagaaaag aaaatcgatg gtccttcagc ttataccaag
     8641 cttgaagaaa tcgacaattc aaatttgcag gaataaggag gaagaatcat gaatgaaaaa
     8701 attattgaaa tcaaacatct aagaaaaagc ttcggtgaaa atgaagtatt gaaagatatc
     8761 agcgtaacag tcaataaagg tgaagttgtg acgatcatcg gttcttccgg ttctggtaaa
     8821 tctactttct tgcgctgtat caatttactg gaaaaaccaa caggcggcga gatcatttat
     8881 aatggagaaa atgtattagc tcctaaatat aatttaccta aatatcgaac gaatctaggt
     8941 atggttttcc aatccttcaa cctgttcaac aatatgaatg tcttggaaaa ctgtatgtct
     9001 ggtcaaacaa ctgtcctgaa acgagataaa gaaactgcca aaaaagtagc aatcgaaaat
     9061 ctggaaaaag ttggtatgga tcgttatatc gaagccaaac cagcacaatt atctggtgga
     9121 cagaaacagc gtgtcgcaat tgctcgggca ttatcaatga atccagatgt attgctattc
     9181 gacgaaccta cttcggcgtt agaccctgaa atggttggcg aagtgcttaa tacgatcaaa
     9241 gacttagcac atactggctt gacaatgctt atcgtgacgc atgagatgga atttgcaaaa
     9301 gatgtatctg accgtgtcat ttttatggat aaaggtgtga ttgcagaaga aggtacacca
     9361 gaagatatct ttgtccatcc gaaagaagaa cgtacaaaag aattcctttc acgtatttta
     9421 aatgcttagg atcaatagct gattgggaca aagagctgcg gtgtttaccg cagttctttt
     9481 ttatgaatta ctcataaaag gtaaatttct gaa
//
LOCUS       DADGHT010000106         9432 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.107, whole genome shotgun sequence.
ACCESSION   DADGHT010000106 DADGHT010000000
VERSION     DADGHT010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.107"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..680
                     /locus_tag="JX887_002429"
     CDS             <1..680
                     /locus_tag="JX887_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1258370.1"
                     /translation="YFSRFSLATREAVQWIVIDMYAPYVSLVKKLFPNAQLIIDRFHI
                     VQHIGRTFLNHRVKETTARLKGTSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRAS
                     FKDYLTESEIVDRLLSACPNLRQGYQLYQDILYAVKKRDQSLFEDCLNREVSGLPETY
                     TTTLRTFKKFLPQIQNALHYSYSNGPLECLNNHIKVLKRNAYGFRSFYNFKLRIMIRH
                     GKTFLTK"
     gene            800..1000
                     /locus_tag="JX887_002430"
     CDS             800..1000
                     /locus_tag="JX887_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAX1258371.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            1076..1273
                     /locus_tag="JX887_002431"
     CDS             1076..1273
                     /locus_tag="JX887_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258372.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(1570..3117)
                     /locus_tag="JX887_002432"
     CDS             complement(1570..3117)
                     /locus_tag="JX887_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAX1258373.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(3201..4004)
                     /locus_tag="JX887_002433"
     CDS             complement(3201..4004)
                     /locus_tag="JX887_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAX1258374.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            complement(4007..4789)
                     /gene="phnE"
                     /locus_tag="JX887_002434"
     CDS             complement(4007..4789)
                     /gene="phnE"
                     /locus_tag="JX887_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAX1258375.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            complement(4786..5565)
                     /gene="phnE"
                     /locus_tag="JX887_002435"
     CDS             complement(4786..5565)
                     /gene="phnE"
                     /locus_tag="JX887_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAX1258376.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            complement(5537..6328)
                     /gene="phnC"
                     /locus_tag="JX887_002436"
     CDS             complement(5537..6328)
                     /gene="phnC"
                     /locus_tag="JX887_002436"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HAX1258377.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            complement(6389..7318)
                     /locus_tag="JX887_002437"
     CDS             complement(6389..7318)
                     /locus_tag="JX887_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HAX1258378.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            7513..8196
                     /locus_tag="JX887_002438"
     CDS             7513..8196
                     /locus_tag="JX887_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HAX1258379.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            8357..9400
                     /locus_tag="JX887_002439"
     CDS             8357..9400
                     /locus_tag="JX887_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAX1258380.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
BASE COUNT         2893 a         1933 c         1869 g         2737 t
ORIGIN      
        1 gctatttttc tcggttttca ttagcgactc gtgaagccgt tcaatggatt gttattgata
       61 tgtatgcgcc ttatgtttca ttggtgaaaa agcttttccc gaatgctcag ttgatcatcg
      121 accgtttcca catcgtccaa catattggca gaaccttctt gaatcatcga gtgaaagaaa
      181 ccacggcacg gcttaaagga acttcccact ctcaacgagg gttagggaaa aaattgaaac
      241 gctattggaa actcctacaa aaagaagaag caaagttaaa ctacgaaaaa agggtttggc
      301 gtgccagttt taaagattat ttgactgaaa gtgagattgt cgatcgactg ttatctgctt
      361 gtcccaacct gcgccaaggc tatcagttat accaagacat tctttatgcg gtaaagaaaa
      421 gagatcagtc attatttgag gactgtttaa acagagaagt cagcggtctt cctgaaacct
      481 atacaaccac tttacgaacg tttaaaaagt ttctgccaca gatccaaaat gcgcttcact
      541 acagctattc aaatggacca ttggaatgtt taaacaacca catcaaagta ttaaaacgca
      601 atgcgtacgg ctttcgcagc ttttacaatt tcaaactacg gatcatgatt cgtcatggca
      661 aaacattttt aaccaaataa acagaacaga aagagagttt cttctttctg ttctgtccaa
      721 attattctaa gatttctctt taccaacatc atttgacaaa gagcctgtat ttattactgt
      781 cgaggacaat ggcatcggca tgattgaaga ggaacaaaaa aacatttggg atcgctatta
      841 taaagccgat ccgtcaagta aaaatacaaa gataggcgag tcaggtcttg gattatcaat
      901 cgtgaaggaa ctagtgcgcc tgcaccacgg ttcaattgaa gtgaccagcc gaaaaaatga
      961 aggaacgacc ttcctgatac aatttccaaa agaaaaataa aattaccagt aaaaaaccgt
     1021 ggagagatag ctgctattga tttttgctat gtcttttctt tgagaggtat ccggtatggt
     1081 ggagtgtctg aaaaataaaa aaatggaggc caattttgtg aaagctgtta tttctggaag
     1141 tattgttttc caagaagaat atcgagatat ggaaaaagat ttcagtaaaa aaggcattga
     1201 attaattgat tatcctcgct catgtccgat cctagacaaa gagtatccag aaatcttgac
     1261 gacttttttt taaatatcgc agcagcggat ttattttttg tatttaatca agatcggaaa
     1321 ggggtattag gctatattgg tgccgcaact ttttcagaaa tgaagtattg tctgatgcaa
     1381 aatcttattc atggaaaaag gatcaaaata gtcttattta aggaaccatc agaggaaaat
     1441 tttttgtttt gatgaggtag atcgctggct aaagaatggc tggatggaaa tcagacagcc
     1501 taacaatttg gcataacaaa ggtgtgggca aaaaactgct cacacctttt tgaatttttt
     1561 atttatatac tacaaaatca cttgaaaatt atgattcact tttgcttcga tgcgtgggtg
     1621 aatattcaaa tagtcggcaa ttaattcggt catgtcgatt tggatttctc ggacaatttt
     1681 ctccgcacca aacatcgcat aatttcctcc gccgattgcc cgatattgat ttgtcaccac
     1741 ttccagcatt tgttgcggaa gaacggggtg acctttaaaa cgaagttcgg taatccgttg
     1801 tccaacaggc tgtttcatat caatagtgta ctgaatccct tcatacatgt cataattgta
     1861 gtactggggc ttaggctgaa taaaggctgg attgaatacg atttggttat tttctacagc
     1921 taaataattt gcggtctgct ccaacgccgc tctcaaatct gcaccattta tttgaatcac
     1981 tgccagagta ttcggataaa tatagttggt gatgacgtcc cgcatcgtga tcgtctcacc
     2041 aaagcctttt ccttcattat tgaataacgc agttccagaa atctctgagc cgctggcaaa
     2101 taattgtaca cgattaataa actctacata gggatgttcc tcaagacgag cctgcatcgg
     2161 atcattaata cgcatatttc cgttcacttt acctaagggt tgatccaacc atttctctag
     2221 tttttcttct accggtacga tcgctgcaag aatttctgga tcaggctctg atttttcaac
     2281 tgagtgtaaa gcaacctggt gatctgtaac aaccacttgc ccctcttttt tctcgacggt
     2341 aagacgaatt tcaccgatga actcgccacg atagcctggt tgaacaacgg gaactccatg
     2401 aaccgtttca gcaattttcc ggtgctgatg accggtgaaa agggcgtcaa tgccttcaac
     2461 ctgctgcaat agctcgtagc cttcattctc tccagttagc gcttctgtgt cctcaccggt
     2521 taacaagtct ttttcaaatc cgccgtggta actaacgatt accaagtctg cttgtttcct
     2581 taatagagga acatattctt ttgctgtttc gacgatactc ttaaacgtaa ttcctgctaa
     2641 ggtttctggc ttttcccagt gaggaatgta ttgtgtcgtt aatcccaaga tagcaatttt
     2701 tacacccacc ttttcgataa tcttataggc gtttccaaag tatggttggt catttttgtt
     2761 caccatattg gctcctaata taggcgcttg ataattctta atcgcttcct cgagataatc
     2821 cacaccatag ttaaactcat gatttcccaa cacttgaaca tcatagctca tttggttaat
     2881 caagtctgta agctctttgg ctgaaccata ttctttagca agataataac tcaaaggaga
     2941 cccttggatg aaatcaccat tttcgatcgt aattaccggt ccatctgctt ttgcccgtaa
     3001 ttccttcagt ttcgacgata ctttagccgt tcctaaggcc agatcggttc tgccggaata
     3061 gtctgttggt gaaacatagc catgcatatc acttgtctct aaaaacgtaa tgttcattct
     3121 gcgtgctcct ttagctgact caaaatagaa aaaccgaagc gtattcagct gttcggtctc
     3181 tttttttgat ttataatgcc ttaatccttc atttgaagtg tttttaaaat gttgcctgga
     3241 ataaagtttt ctgttgtctg gcgaacaatc cttccttgat cgagatgata aaggttatac
     3301 ccatgacgtt cttcaaagcg tacgaagcca tcgccttcat cttcaccaac aaaggacata
     3361 ctcgatacag taaaataggg gatcccatta atttcatcag taaatgtgtg atgggtatga
     3421 ccgtttagga tacagcgaat atcgtaaggt gcgattagct tcaagaaacg ttcggtacca
     3481 ggccattttg gtatactgct ttggtgagac agtagatgat gatgggtgac caagaaaatc
     3541 ggttggtctt tttcttgctc taaggctttt ttcagccatt gaaattgctg atcgtccact
     3601 ataccatctg cgtatccata gcttgaatta tcaaaggaaa tcactgtaaa ctcaggatat
     3661 ttgactatct ggttgtacgg ggcagaagag gcggcttcat cgcaccagcc tacccaaaaa
     3721 tgttctttga tatcgtgatt gcctagagta acaagaatcg tcgtttctcc tagcgcattt
     3781 tccagccaag tcttcaagta tcgataatcg tctatttcgc catcttcggt taaatctccg
     3841 ctgataatca caaggtccaa gggtgtttgc tgcaggagat gatgaatgca ttgctccaga
     3901 gggataaggg gattctgcat cgtagccagc attcccttat agccttcttc acaagcctca
     3961 tactctctgc gaaagtgtat atctgatata tgcaatatat tcattcttat ctcaatctct
     4021 ttcttataat tccggttatt tgatctaaaa taaacacggt tacgactacg ccaatcaaaa
     4081 taatactcac tttgctccaa gaccgagttt gaatcgcgaa tatcaatgga gcaccgattc
     4141 cgccagcgcc aactaagcct aaggtagccg cactacgaac cgctatttca aaatgattta
     4201 atgctaaaga acaataaatc ggcatcaaat aggggatgcg aacaaagaaa atcgtttgcc
     4261 aaaaatttgc tcctaccgca tgcatttctt caacaagtcg ctcatccatc gcttccattt
     4321 cttctgtaaa aagtttgcca agcattccga tctgatggac gccaatcgcc ataacaccag
     4381 caaaggggcc aggtccgacg actttcacaa aaataattgc aaaaactagt tcaggaaaag
     4441 ctcgtaaaac attacagata agcttgccaa tttttgttac ccatggatgt gcttgccaga
     4501 ggttaaccgc actgatcaag gtaatgggaa tcgctaatac cgtagcgatc attgtcccta
     4561 aacaggcgat tccaatggtt aataatagca aactaatcaa atcctcgccg ctgccatcat
     4621 atagaaactg ccaatcaggc tgacctaacc ctctcaaaac gtccattccc atggaaggag
     4681 agaaggtgct taatccagag taatccagag tagcggccga caaaataacg agaatcacta
     4741 aagcaactaa tgataaaagg gttcttctgt tcatttcacg aagcatcata acagggacct
     4801 cctgacacgt tcacttaatt tatcaacgat cgcgacagtt actaggatcg ttagaataat
     4861 gattgaaact cgttcataat tcaaaagcgc aagtgaggaa tttagaataa cgccaatacc
     4921 accagctccg acatatccaa ggacagtaga agcacgaaca ttcacctcaa acgcgtaaaa
     4981 agcatagctc gcaaactgac tcaaaacttg tggagcgatc gaccaaatag cgatttgcat
     5041 tttatttgct ccaacagccg cagcggcttc aatcgggcca aagtcaatgg tttcaattgc
     5101 ttgaaacatt aattgtgaca ccataccaaa agtaaagaca gcgatagtca acacgccagt
     5161 cgcttcacca attccaaaca cagcaacaaa aagcgcggct aaaagcaggg tagggatggt
     5221 ccgtactaaa cctaaaagaa aacgaaagat ggtagaaaga agacggtttt ctgtcactac
     5281 agtggtcgct aaaaaactaa cagggatcgc taaaattaag ccaatgaccg ttccaagcaa
     5341 agacatttga agtgttttca ccataggctc gactaattta ggtaaatagc taaagtctgg
     5401 atgaatgaag cgtgataaaa agacagtcat ttgattggag ttttgaaaaa cctgagaaaa
     5461 atcagctgac gtgatccagg cacttccttg aaaacaaaca attaagaaca gaagaataag
     5521 caggtgttta taccatttaa agtgaacggt ttctttcaag ctcatcgatt tcgcctgcct
     5581 tttcttcaaa gattgcattg ccataaattt gctctaagcg ttcatcggtt aagtcgtctg
     5641 gacgaccatc aaagacaacc tgagcagctt ttaacgcgag cacacgcgta gaaaactcac
     5701 gagccagagg gactgaatgc agattgacaa tgactgtttt atccatcgtt tgattgatat
     5761 tttttaggtc catcataacc ttttgagtcg tgattggatc taatgatgca acgggttcat
     5821 ccgctaaaat aatgggggct tgctgcacga gtgctcgcgc aatggatact cgctgttgtt
     5881 gcccaccact gagctcatca ctgcgtgtct gcaatttatc agacaaacca actttttcca
     5941 gtgcttcctt tgtctgctgg tagtcttcct tcgtaaaaag acctaaaata cttttccaag
     6001 tggagtaata gcccaaacgt ccagatagca catttttctg aaccgtacta cgctttacca
     6061 gattgaagct ttgcgagatt agaccaatct ggcggcgaat ctgtcgcagc tcttttttat
     6121 tcgcttttgt aatagaggtt ccattaatgc gaatatctcc tttggtggtt tctgccaagc
     6181 gattgatact gcgcagcaga gtgctctttc cagcaccact caaccctatg atggaaacaa
     6241 attctccatc ttcaattgtt aagtcaatat ccttcaagcc aacaacgcca ttgggataga
     6301 ccttcgaaac attgtcaaaa ataatcatta tccttctcca tttttttaag tgtaagcaaa
     6361 aaaaagcttg ctgacactta ctgatgtttt attctgctgc ttttttcgtg tagtctctga
     6421 tcgtgtcata ggcagaatca gcagcttctt catagccctg atgcccccac aaagccattg
     6481 cttctttgcc atctttatca tccttcatat ttaagaaggt ctctttaatt ttcgctttta
     6541 aatcttttga catgtcaggc tgtacagcga ttgcgtcatt cggaatatcg ccttttgtca
     6601 ggtacaggac ttttaaatcc ttaaataaat cattatctgg gaaattcgaa gcaaaaacat
     6661 ttcgcgcgcc ttcaaaaaca aacgccgcat ccatttgctt gttcaacact gcggtaatct
     6721 cactcggaat atcattcaca gtggtcatct ttgtatctgc agtaggatca atcccagcat
     6781 ctttcaattc agcgacagga tagatgtagc cgctagcaga gttaggactt aaggttgcga
     6841 tattttttcc ttttaaatca gttaacttat tcaatccgct atcggcacga accaatactt
     6901 ctcctttaaa ggtgttcgta agtttgtcct ttaatggcaa gccagtttct tgatcataat
     6961 cgccgagctg agaagtcagg attgcatctg cagctccagc atcctttgct tgaacatagg
     7021 ctgcaggcgg cataattccg acatcgactt gaccagaaga catcgcttcg acgatcgttg
     7081 aataatcagt agctaacgtc acttctacct cacgatctaa ctttttcgat aaatacttag
     7141 caaatggttt tgcttttgcc tccatactac catcattgtt tgttggaacg aattgaacaa
     7201 ctaatttttc tttgctctct ttttctgagc tgctacttgt attcccagaa ccgcaggccg
     7261 ccaaagtggt caataacatg actccgatga acccttttgc taactgtttg aactgcattt
     7321 ttctcctcct gttggatata atttctaata cgtctaaatc atagcaggga atcaaaatca
     7381 atgaagtgac gcacgtccta ttttacacaa cttttacata caatttacaa acaattataa
     7441 ataattattc gtattgagcc gaaaaacaat ctaagctata ataaagaaaa acttcttaga
     7501 ggtgacgatt tcatgaaaaa aatccatgat acgaagcaat taactgctta cgttgagaag
     7561 cacaacctgc aggattatat ggattcagat atattggcaa tggcttcttt actttttttt
     7621 gaaaaggaag agcacctcat tcaaacggga aaaacctcag attatttgta ttttttagtg
     7681 gatgggacgg taatggtgta ctcgtattct tctgatacac aaaatatttg catcgattac
     7741 gcaaagcccg ctacaccact cggcgaagcc tcttcattgt gggaattatc gccgaaaagc
     7801 agcgttaaag cagtgactaa gtgcatctgt atcagcattc cgctaaatca atatcgaaca
     7861 cagcttcaaa aagatgttcg ctttttgcag aatatttgcc agttactaag ttatcgttta
     7921 aattccggga taaatttggc gaactcactg acagaacctg ttgaaactcg tttagcaaag
     7981 tttattttga cccatcacga aaacgaacgt ttctcatttc ggttaaccac ctgcgcctca
     8041 atcttaaatg tcagttatcg acatctttta cgaacaatca cgaattttcg tgaggagaat
     8101 attatcgaaa agaaaaagaa ttattacttg attcatgata tcgaagcttt agaggactta
     8161 gctgagaata taagtagtcc agtaaaagca gaataacagc tataaaaaaa cagcagtcag
     8221 aagtgattgc tggttttttg atagtggaga aattgggaaa cggaaaatct tcgttgaaga
     8281 gtagtgttct atatattggt atgctatact tttaaaagtt caatgtgtca agacacataa
     8341 aaaggggaga aaaattttga agaaaatact tgtttcattg ttgtttttgg tgtcattagt
     8401 aacgttagtc ggctgtagtc agtctcaggg ggagaagcaa agtgaaaaag agaaaagtaa
     8461 aatcgctttg gttcttggat ttggcggggt tgatgaccgc tccttcaatc aagctggctg
     8521 ggaaggatta gaggcttggg gaaaagagaa aaagctgaca gcaaaaaaag attttacgta
     8581 tatagaaacg aacaatccag aggataacag taccaatatc gatcaggcaa tcagaaacgg
     8641 ctttaccacc attattagct tgagctactt gcaagcagag gaactggaaa atgctgctaa
     8701 agataatcca aagttgaaat ttgccttggt agatggtgag attactggga aaaagaatat
     8761 ctcatcagca acctttaaag atcaagaaag tgcgtattta gcaggactag ctgccgcata
     8821 tacgacaaaa agtgatcaag taggctttat tggtggaatg gaagggcccg tgatccaacg
     8881 tttccaaagc ggatttgaag ctggcgttaa ggcaggggcc acagcactga acaaggaaat
     8941 tactgttaac gtacaatatg ctgcatccta tgattcgcta gataaaggaa aagctattgc
     9001 tgcttctatg tacaaagagg gagtcgatat tctttatcag gcggcaggaa gtactggagc
     9061 tggggtgttc caagaagcaa aagcccgcaa tgaaaacgac tatagcagaa aagtatgggt
     9121 gattggtgta gatcgcgatc aagcggatga aggggattat aaaatggaga acggcgagac
     9181 agggaatttc acgttgactt ctacaaagaa aaatgtcggt gcagaagtca aagaatttgc
     9241 agaaacttct cataacgata aatttcctgg cggcaagcat ttgacctttg gtttgaaaga
     9301 agaaggggta gatctgacaa aaggacaatt atcagaggaa gcctatcagg cagtttcaga
     9361 cgcaaaagag aaaatcatca gtggtgattt cagactgtag acaaagtcca ttttatggat
     9421 gatgtctaca gt
//
LOCUS       DADGHT010000107         8978 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.108, whole genome shotgun sequence.
ACCESSION   DADGHT010000107 DADGHT010000000
VERSION     DADGHT010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8978
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.108"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            141..398
                     /locus_tag="JX887_002440"
     CDS             141..398
                     /locus_tag="JX887_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258381.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1043)
                     /locus_tag="JX887_002441"
     CDS             complement(630..1043)
                     /locus_tag="JX887_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HAX1258382.1"
                     /translation="MDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVLSASIPI
                     LIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEKLLYITK
                     TSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
     gene            complement(1412..2104)
                     /locus_tag="JX887_002442"
     CDS             complement(1412..2104)
                     /locus_tag="JX887_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1258383.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            2189..2365
                     /locus_tag="JX887_002443"
                     /pseudo
     CDS             2189..2365
                     /locus_tag="JX887_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(2541..3110)
                     /locus_tag="JX887_002444"
     CDS             complement(2541..3110)
                     /locus_tag="JX887_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAX1258384.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(3184..3507)
                     /locus_tag="JX887_002445"
     CDS             complement(3184..3507)
                     /locus_tag="JX887_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258385.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(3661..4473)
                     /locus_tag="JX887_002446"
     CDS             complement(3661..4473)
                     /locus_tag="JX887_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258386.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            4827..5675
                     /locus_tag="JX887_002447"
     CDS             4827..5675
                     /locus_tag="JX887_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAX1258387.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            5820..6761
                     /locus_tag="JX887_002448"
     CDS             5820..6761
                     /locus_tag="JX887_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAX1258388.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVCLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            6751..8922
                     /locus_tag="JX887_002449"
                     /pseudo
     CDS             6751..8922
                     /locus_tag="JX887_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2776 a         1684 c         1549 g         2969 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaatagat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatccta aaatataagc
     1201 tatttgttta cttctgtaga atatatactt tgttgttaga taagttgcac atgtttatag
     1261 aatctaaata ataaattttt atgtaccgcc cctcaaagtg aactgaaccc caaaagttga
     1321 actatttaat ggactgtttc cgatattcta ctggagatag tccattaaat agttcaactt
     1381 ttggggttca gttcaaagag ggggggattt tttatcgttg tggaatattt aaataccaac
     1441 gcttgtcatg aaaatcttgt gctccaccct tagtatttcc ttctggatcg tttgtcgcac
     1501 gcatcatgac gtatactttc ttattaggga aatcacgcat attgaaagat acatgatagc
     1561 caacatttcc taaagtatta taagcttgat ttacgtctgg tctataaatc ccatcagctc
     1621 ttactctagc tagttctttt ccagtattgt agtccataat gaaaatatac tcgtatttat
     1681 aattagcaat gtgccatcca gctacatgca agtttgcgtt ttcgatttct ccgaactgat
     1741 caatgtgggc gtaatttgtt ccatctgtca gcgtagaatt tgcagcacct gctcgagttg
     1801 gatcaattac tggtttatcc tccgaagtag ttggattatc atccgtaaaa ccatgagcca
     1861 aatcataggc tagtttttct ttacttacac ccatttcaga aagataaccg taaggatctg
     1921 tatgatcgcc ccaaatattt tgtgttaccc ataaatgcga tttgattcct ggttggttat
     1981 aaggagtgtc taatgttaat ggaataccat atttcattgc tgaatctctt gccaattcaa
     2041 cgtatacttt atagttcttt tcaaaagttt ctttatcatg tgtatgttgt aactcgattt
     2101 gcacaggact tttggctcac gaggttgtcc tactctacat cttgctgata gatatgctga
     2161 aaggaaaaca ccaacattat gttttgcttt ttcagctaga acgagacaag caggaatacc
     2221 tttagaagat atcaaaggtt ttttaggtca taaagatgtt tccactacac aagtctatgc
     2281 ccatatttct cccgaagtga aaaaaagatc aatgaatcaa ctagaaaact atatagaaga
     2341 gcaaataaaa aagcactcaa attgagtgct tttttaagct cactatcact aaaactatca
     2401 ctaattttat ttataagcga acatgtttct atcactgatt ttttaaatct agcgaaaaac
     2461 ccttatctta aaggcgttcg ttcaattctt tggcaaggtc ttcaaagcct ggcttgccta
     2521 gaagtgcgaa catggttttc ttatagctca tgtagaaaaa ttttcttgat gatgatttta
     2581 tccatcaatt gagattgact gttttgctct cctatgattt cagctatgat tgtccgattt
     2641 tgcggttttc ttcttaactg gtagttgatt ttcccagttt ccatcaactc gctaagcata
     2701 tccacgactc cgccaaatcc ggtctttttc gtaataaaac ctagtgctac cattcgttca
     2761 tctagatttt ttgctgtaat cgtcacacca gtaatgagcg agtgctgtaa tgtttgggcc
     2821 agctcttcca tcccttcagc attggatacg acggaagctg ttttgttaat aggttcttcg
     2881 tttatttctt ttggttcttt cctctccact ttcactgttt gacgaaggac atctagttct
     2941 tgcaagagcg tttcgtattg ttcttgggtc agcatcacgc cagctacttt ttcacgatta
     3001 aatatatata cgccagttcc cgcgtctcgc gcttgagcaa atacatccat cggcgatcgt
     3061 ttcacttctg tgatcgaaga tgtgggaact tctaatttct ttaattccaa tggatttcct
     3121 cctttactaa tcgcttttta ttatagcaca gactgacttg ttttgatctt ttttccaaag
     3181 gttttatcgg tttttgccta accagtaatt gatatcggta agaagtcttt cgataccaaa
     3241 tgaaggatgg tacagatacg ttttttgatc ttcgttatgg tctagtggaa aaaaatgatc
     3301 gatgatcact agatctgcat accgaggcgg cttatttcga gtacatacat gtatagagat
     3361 ccgttttcga tgtcttagcg ttttgttcag taccccagca agtcttcttg cttcttggtg
     3421 ttcatagcga aaaaaaaaga cgattttcac ttcaggaggg tggacatcta aataccctcg
     3481 ttcctggagt gttttcagta aaagcatccc ccactctact gcggggtgtg caagtgcttg
     3541 ttggatcgct agccgaaatt gatatagttt atctttggaa ttgggaaatt tttctaatgt
     3601 ttcctgataa taacgaactt cttctatcag ccggtcatgg ataccaatta cgtaacgaag
     3661 tcattcttgg taaagtactt ttgtcagctt tgatttgctt tcgctctcaa attcgctatt
     3721 cagccaaaac agcgaatcaa gcttttcagt cacaatcgtc aatttccgat agtcttgtgt
     3781 ctcttctatc cgtttccacc gcttttcagt aatctggtta cagctcaagc gcaaaattgc
     3841 tagataattt ttttctttta ttggcaaaat ctgctcctct ctaaatagca attcaggaaa
     3901 caattcaaag aatagtgttc gactgtctcc taaaatctcg atttctgccg gatcctttct
     3961 ttgcttcaat aattggatga acatctcaga aaaggactgc tctccatcat ctgcaaaaaa
     4021 atgcggaaaa tctttcaaaa agcaaaacag cagatatctt acttttcttt ctgaaccaaa
     4081 gatctgtgct tttttataag aaaaagaaag gtggtactcg ccaaaccact ttctcaatcg
     4141 ctcttgcgta gaacgatcgt acttctgctc gtaaggttca ttcaatagca gatttttcag
     4201 taaacaaaac gggggtgatt ggatcagaaa aacaaacaag agataaggtt cgctatatcc
     4261 ttgatcataa actaactgaa cggttttctt atgaagaatc agctgaatgg gacagtcgct
     4321 ttccgccaaa cgtttcagat gccgatccac tgttttaaca tcgattttca gttcttcagc
     4381 taaatcagct tttcgccaga tcaaatcttt cattagattg attagtgaaa ataaattctg
     4441 tgcatttttt gataatagtt tttgccatct catcgatcat ttctcacctg atttctaaac
     4501 atattgtttg atcaaaatgg gttcactcct aaaaagataa aaaactccct ttctatttat
     4561 ttaaatacgc aaatcttcct cattattttt tattttactc aatttaatcg tattctcatt
     4621 tcaaaacgaa tgtactttaa aaaaacataa taagatcact ttgcttgtag gatgtattcc
     4681 cttccattac aatgaaataa atagcgattt tatgagaagg tgatgtgaaa atggaagaaa
     4741 aaatagaaga atccaaacaa aaaatcgatc agttgatata agaattagaa aaagcggtca
     4801 tcggcaaacg ttcaactatc caattgatga tcgtggccct attagcaggt ggtcatgtct
     4861 tattcgaaga tattcccggt gtaggtaaaa cgttactggt caaagcacta gcaaaagctg
     4921 tacagggaac cttcagcaga gtccaatgta ctcctgatct gctgcctagt gatattcttg
     4981 gtttttccgt atacaattca caatcaaaag agtttgaatt tcgtccggga ccgatcttta
     5041 ccacgatctt gttagcagat gagatcaatc gtacgactcc tcgtactcag tcagcacttt
     5101 tagaagcaat ggccgagaat catgcaacga tcgacaacaa tacataccct ctagacaatc
     5161 atttttttgt cttagctacg caaaatccaa tcgagtacga aggaacatat cctttgccgg
     5221 aagcacagct cgatcgtttt ttattccgac tacaaatcgg ttatccttct tttgatgacg
     5281 aacttttgct acttttggat aaattcgaaa aagtgttgga taacttaaat gaagtattga
     5341 acagttatga aatagaagaa ataaaaacaa atgtggcgaa tgtctttgtc agtcccgaag
     5401 tggcatctta tgccttgcag ttagtgtcag caacaagaag tcatgctgcc atccagcttg
     5461 gcatcagtcc acgaggaagc ctttccttta ttcaggcagc aaaagcttat gctttaatcc
     5521 atgggagaaa ttacgtcacg cccaaagatt tgcaggattt agttccttac gtgttttccc
     5581 atcgcctgat tttttacgat cgttcattga aggaagacga aaagaaacaa atcattcata
     5641 ctcttgttgc acaaattcct attcctgtga ggtagattga ggtagacaat ggaaaaaatc
     5701 aaagattatt tcattaattt tgtgttattt ctggtatatt tcatcattgt gctttttgct
     5761 cttgtattca acaattcttt aggctggttc ttgttggcct tttttactct ttatgtatca
     5821 tggagcttga tttcattaag cagctttcta aagaaacttt cggttacttg tacattgcag
     5881 ccactcgttt atcgcaaaaa aagtatgcag gttatttttt ccatagcaaa aaagagaact
     5941 ttttctttac ctctccctcg tttacaaatc ggcttcccag caatctttgc agaaaaaaac
     6001 aagagatttt gattcttaca aataaaccgc aagaagtcca attgctttgg cagccaaaag
     6061 aaagaggatg ccatgaaaca ttaactgtca tttttacagc ctatgatagt ctaggacttt
     6121 tcagaaaaag tgcaaaaaga gagatctctt ttcctgtgac tgttctgcct gctttttgta
     6181 agattcaagc agaaaaatta cagagagttc tggaaaaaaa acagcagctg aacgcgtacc
     6241 aaagaggtct tgattttcgg gaacatcgcg cttatcgtcc aggtgattct ttcaaccgaa
     6301 tcgattggaa attgtctgct catactcaag agtggttata ccgtgaatac gattatcaag
     6361 aagaagaatg ttctcctctt ttttgctttt ggggttcgcc cagtccaaaa tttgaacctc
     6421 tgctagactt gtatttttct ttatggcatt tgagaaaaga aaagcagccg gaacttctga
     6481 tattaggcaa ccgcgccttt catggcaaag accccggtca tacctatttt gcttctttgg
     6541 aagctggcga tgagaaagct tttttcgcac acttgaaaaa atatgcaaaa aaacaaatcg
     6601 tcctctttgt tcctgagaat tctcctgaag tctcagaagc tattgaaaca ttgtcaaaag
     6661 atcgaacggt ttgtcttgtt tatttcgtag aaaaacaact catggtccaa gaaaaagaca
     6721 agatatgttc attgccagga ggtgaatgga ttgacgatta aacgggaaaa atggctgcgt
     6781 ggcgtttact cctttgtgat actaagtgta ggtgctccga tatttgtagt agctaatcaa
     6841 ttgcaaaaca gctaccttct tatcctaact attggtgtcc tatgccttat tgtctgctgt
     6901 attcctaaaa aatgggtacg tttgctgctt tctttgccag taatgatagg ttgtttgttt
     6961 ttatattttc cttcgaagac attttccata ttatggatct tacagttttt ttcgtcagtc
     7021 acagaggaat tcttccatct atcccaaggt aaactttatt atttgccaga aaagacagct
     7081 ttttttctca taatgttgct gatctattta tttattacat tgaccgtgga ttacgactat
     7141 tggtacgcac cctttctttc tttgatggct tacttcatga tgcttaccgt ttttcggaaa
     7201 aaagatttac tgtacgaaat gattgcggta gtaactgttt tgttcgtgta tctggcagca
     7261 aggcaatttt tctccatccg gttgttgtcg ggaaacactc gattccagtc attgactaca
     7321 gttctgctta tttgtttctt aacttttagc gctatcttgc ctttatatct tccgaaagta
     7381 caccaatctc tcgaggaaac gagtgaaccg atccgagaat atcttaatga tgaagggctt
     7441 tatgacacac tccatgagta tcaattaacc ggaagtgcaa gaacaggctt cagtgagaat
     7501 gatgaacagc ttggtggacc tttatatgat aatggcgaag ttgtttttac agcgaaccaa
     7561 aaaggaaatg gctattggaa gatcgaaaat aaaaatcatt acaccggttc tggatggata
     7621 gaagatcagg acgcacccat ccaaccaatc caagaattcc ctgttgacat cacgagctac
     7681 caaaccgtta tagaagacaa agaaaacatt acattgaccc taaaaaaaca agttttctta
     7741 ccttatcctt atggaaatac taccttgact gatttttcat tagctagtgg acaaacgctt
     7801 tactatttgc ctgaaagcca gcgattcatt cctgtcccga atgaatcgac acgttctgca
     7861 actttacaaa cagaaaggtt agtttttacg agagaagaat taaaaagcag tcagttaaaa
     7921 gctgatgatt tagaaaatca gcagacaaat cttcaattgc caaaaagttt gcctaaacgt
     7981 attgaggact tggcggtcga attgaccaaa aatgaagcaa ctttaattcg taaagtcgaa
     8041 gctgtctaac agtatttaaa aacaagcgga aatttccgct attccaaaac ggataccggg
     8101 catactccaa aagaacacga ttatgtggat tatttcctct ttgattcaaa agtcggctat
     8161 tgtgacaact tttcaacttc tatggtcgtc cttcttcgaa cacttggtat cccagctcgc
     8221 tggacaaaag gttttacaaa tgggctcaga acaggcacag ataatcaagg gaatgaggaa
     8281 tacagcattc tcaatagtca tgctcattct tggccagagg tatactttcc tggatttggc
     8341 tggcttccat ttgaaccaac cccttcattt gccaatccaa tgggttcaca accagttgct
     8401 gaaacaaccg aaaccgtcca gcctgctatc gaacaaccaa atgaaagcga aaatatggca
     8461 gaaactattt ccagtgagag atctgaggtc attccatcag aagaaacaac actcacacca
     8521 gcttataaaa tcgtcttatt cagccttgga gtgtgtttat ccgtcttgtt gttctttcta
     8581 ttgttattca gaaaatctct gcgctggaca agttatctta tctatcttca tttttttgct
     8641 tctactaata cgattgcata tcaaaaactt cttaaccctt tggaaacatt ggtaccgcgc
     8701 aaacccgcag aatctttgca ggaatatagc ctgcgaatag aacaagaatt caagctagat
     8761 ctgcgtttca ttcgattaac tactcaatat gaagcagaaa tatatggacg acaagcagat
     8821 ccggtaaaat tcgataaaaa aacctattta gaaataacgc atataataag aaaaatggta
     8881 tacaaaaaaa ttctgacaaa agggagccgc ttcaaaaaat aagataaaat ttctggagaa
     8941 tctacttctg gaatgccgag aaccagctga ttgagtat
//
LOCUS       DADGHT010000108         8793 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.109, whole genome shotgun sequence.
ACCESSION   DADGHT010000108 DADGHT010000000
VERSION     DADGHT010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8793
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.109"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            225..2060
                     /gene="tdc"
                     /locus_tag="JX887_002450"
     CDS             225..2060
                     /gene="tdc"
                     /locus_tag="JX887_002450"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAX1258389.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            2365..3843
                     /locus_tag="JX887_002451"
     CDS             2365..3843
                     /locus_tag="JX887_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1258390.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            3809..5140
                     /locus_tag="JX887_002452"
     CDS             3809..5140
                     /locus_tag="JX887_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1258391.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            5254..7806
                     /locus_tag="JX887_002453"
     CDS             5254..7806
                     /locus_tag="JX887_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAX1258392.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(7813..>8793)
                     /locus_tag="JX887_002454"
     CDS             complement(7813..>8793)
                     /locus_tag="JX887_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258393.1"
                     /translation="RAIRTFYHRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELA
                     VETEEIFGTCWFFINTIRIKANCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTE
                     LSFASFCFLESWNYNNNYGQETARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTD
                     NLALLILKYHESPILIEALDRQYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPN
                     YFLQLLSLLIQQTIFSIKPNLFNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELT
                     DLSTISFEKTDILISNFPLDSLDIPIVYISSIPTKNELNRLTELTFKTFL"
BASE COUNT         2764 a         1457 c         1899 g         2673 t
ORIGIN      
        1 tttaggttat ctattttaga agactgattt attgaaaaat tgttcgcttt tttgcgttga
       61 attatcagaa aaatccgact ttatttattt ttgtttgtaa aaatctacgt ggatttgatg
      121 ttataaaaaa aaaattctca tttttggcgc tatagtgaag aggtgttaca gataaacaca
      181 tgtatctgca agacattgac caacaaaata tggagggaag aaaaatgaaa gatatggata
      241 tcaaggccgt ctttataggc gacaaagctg aaaatggacc agtttataaa atgttgttga
      301 acaagatggt agatgaacat cttggatgga gagaaaatta tattccttca gatatgcctg
      361 caattagcga aggagataag ctcactccag attatctagc cacccgcgac catatgatag
      421 aggtcttgga tgaagtcagt cagcgattac gcgcaggatc gatcccatgg cattcagcag
      481 gccgttactg gggacaaatg aatgctgaaa cattgatgcc tgctttatta gcttacaact
      541 atgcgatgct gtggaaccca aataatgttg cattggaatc ttctatggca acttcgcaaa
      601 tggaagcaga agtaggacag gattttgctt cattattcaa tatgacagac ggatggggac
      661 acattgcagc agatggttct attgctaatc ttgaaggatt atggtacgcc cgttgcatca
      721 aatcgattcc tttagctgtc aaggaagtgc tgcctgaaaa agtgaaaaaa atgtctgagt
      781 gggaactttt gaatttatct gttgaagaaa ttttggaaat gaccgaaagc tttacggacg
      841 aagaaatgga tgaggtcaaa gcagcttctt cccgtagcgg aaaaaatatc caaagattag
      901 ggaaatggct ggtccctcaa acaaaacact attcttggat gaaggcgtta gatatttgcg
      961 gagtcggctt agatcagatg gttgctatcc cagttcaaga ggattatcga atggatatta
     1021 atgctttgga aaaaacaatt cgtgaattag ctggacaaaa aatcccaatt ctaggtgtgg
     1081 ttgctgtcgt aggaacgaca gaagaaggtc aagtagacag tgtagataaa atcgtccaat
     1141 taagagaaag gttaaaagat gaagggatct atttctattt acatgttgat gccgcatatg
     1201 gcggctatgc gcgttcactg tttctaaacg aagcaggaga atttgtgccg tatgcttcct
     1261 tagctgaatt ctttgaagaa catcatgttt tccaccactg cgtaacgatt gacaaagagg
     1321 tatatgaagg gttcagagct atttcagaag cggattctgt cacgatagat cctcataaga
     1381 tgggctatgt cccttatgct gctggaggaa tcgtaatcaa acataaaaat atgagaaata
     1441 tcatttctta tttcgcgcca tatgtgtttg aaaaatcagt aaaggctcca gatatgttag
     1501 gagcttatat tttggaagga tcaaaagctg gagcaaccgc cgccgcagtc tggacagcac
     1561 atcgtgtatt gccattgaat gtgaccggat atggtcaatt gattggggct tcaatcgagg
     1621 cagctcaaag attcagagaa tttctcgatc atctgacttt tactgttaaa ggaaaaacaa
     1681 tcgaagtcta tccattgaat catcctgatt ttaatatggt caattgggta ttcaaagaac
     1741 aaggctgtac agatttgaac gctatcaatg aattaaatga aaaaatgttc gatcggtctt
     1801 cttatatgga tggcgatgtt tatggtgaac ggtttattac ttctcatact acatttacac
     1861 aagaagatta cggtgattct ccgattcgtt ttgttgaaag aatgggtcta acgaaagaag
     1921 aatggaaaaa agaacagaaa atcactctgc tacgtgcggc tatcatgact ccttatttga
     1981 atgatgatcg aattttcaat ttttatacaa aaaaaatcgc caaagcaatg gaaaagaaac
     2041 taaacgaaat catccaatag aactgatttt tgtgtgaaag aataacaaga gacatatgga
     2101 gaacagacaa ttatttgctt catcaaaaca attgtatttc cccctgtttt tcatatattc
     2161 ctcgccaaga tattcttttt tataaaacgt tctataagtt ggatcgttcg tttcatgtat
     2221 caaacccagt tcactaagat cgttcaatgg atgtttcggt gatactgggt tttgtactga
     2281 atcgatgaaa ccttgtcatt tctgttcttg aacaaaaata aaagaaaaca aaaacatatg
     2341 tcgctattga aagaaggaat aaagatgaaa gatactggtt catcaaagca aatcacgacc
     2401 atgaccttta tcggaatgac ctgcgccctt gtagcaagtg tacgaaatat tccagatgta
     2461 gcagcaacga gctggacgat gattttttac atgctggttg cagtattatt gtacgctttt
     2521 ccaatctcat tgatctctgg tgaatttgct ggaatgtttc cccaaaaagg tggtccagaa
     2581 ctttgggtat cgaatgctct aggaaaaaaa tgggggttcg ttgtctcatg gctgttatgg
     2641 gtccaaatgt ttcctgggat ggtgatggtc gcttcagcac tcgctccgtt gtttggtaat
     2701 attatcgata atgtgccgct tggtttgaac agcaaattta cattagttgt cattttagtc
     2761 gtttattgga tcatcacttt tttgaatttg aaatttgata tggcaaaaat cggcggaaaa
     2821 gtcggtgttt ggttaggatt gtacgtgcct ttgacgatga tgctcttatt agggtttgct
     2881 gcgtggatca aagttgggat cgtaccaacc ggaacattag gcagtttttc atgggacaaa
     2941 ttaataccag atactacgac tgcatcctca tttgtttatt ttgcgccgat catgtttatt
     3001 tttactggta tcgaaatgtc ctctgtgtat atcactcgat tggaaaatcc agttaaaacg
     3061 tatattcgcg gagtatttgc cgcgttaatt tttatatttt tcgtcaatat tttgaatgct
     3121 ttagttgtag caaatgtcgt accaaaagga caaatggaat tgaataatat cgcgcaatct
     3181 atttcgattt attgccaaat tcttggtttg ccacatctta ttgtgaatct gtttagttta
     3241 cttgtcttca ttggtgtagc agtccaatta tctgcttggg cctcaggacc agcaaagaca
     3301 gtgacagaaa gtgctagaaa aggtgcgtat ccaccaaaat tcaatttttg gaagacgaat
     3361 caatttgacg tatccaaatc cgttattttg actcagtctg tcattatctc aatctttgca
     3421 cttttttatt tgctgattcc tggcgtcaat caagcatttt tgatgctcgt aaattcaact
     3481 actgttatct actgtatcgt ctatgtcatc atggggatcg cagttttgag attgcgttat
     3541 acacatgcaa agttgaatcg accatttaga attggaaaaa aagagaaaaa gagcaatctt
     3601 ggagtttgga ctgtcgttat tgttttattt gcggcaatcg gattttctgt cggactgacg
     3661 atgaaagctg gaacatggat caatctaatt gcagtcacag ccatcagtgt cattttgttt
     3721 gtagtaccac tctgtattga aaaaataaag aaaccttctt gggaacagga agtcgccatg
     3781 ctgcttgaaa aagaaaaagg tgaacttgat ggaaaaaccg gcaatgaaac ggactctaac
     3841 taatcgaaat atccagttaa tcgcattagg tggcgcaatt ggaacaggat tatttttagg
     3901 ttcagcaaag gcaattgcat cagcagggcc agctgttatt ctcgtttatt tgatatgcgg
     3961 tttggctatt tatggtttga tgcgggccat gggtgattta tttttagcaa atagtacatt
     4021 taactctatc agtgatttcg ttgactatta tttaggcaaa aagtgggcat tttttgtcaa
     4081 ttggacttat tggctttgct ggcttggagc tggacttgcg gaattaacag caataggatt
     4141 gtatatccat ttctggtttg tacatgtacc agctttgata agcggaggta gcgcactaat
     4201 gatcttaatg gcagtcaacc ttgttgcagt caagtggttt ggtgaattgg aatctttttt
     4261 ctcaatcatc aagatcttgg ggattttcct ttttatctta ttgggtatag gattgagtgt
     4321 ctcagatttt catacccagt ctatcggaat caaagaaaat tttggacaga tcgatgaatt
     4381 actaccgttt ggctttgctg gaatggtagt ctcatttcct atggttttat tcagttttgc
     4441 tggaattgaa atgatcggct taaccgttgg cgagacaagt gatccgcaaa agaatttgaa
     4501 aaaagcaatc aactgtctgc cttggcgtat tctctttttc tatataggaa cgattttgtc
     4561 gattttattt gttgttccat ggcattgttt agatttaaaa gaaagtcctt tagtgactat
     4621 gctgcaagtg atccattgcc aaggcggagc agcaattgtc aatctaatga ttttggttgc
     4681 ttctttgtcc tcagcaaata gtgcagtcta cagtactagc aggattttat atcaaacagc
     4741 aaaagaaaaa agtttgcccc attggttttg tgcgctttct aagaaaggcg tacctttaca
     4801 cggtatttta attacaggaa tgttattttt tgccggtctt tgtctacatt tttttgtagc
     4861 tgatagtcga ttgttttttc agcttttggc aggcatgaca acgagttgtt ttctatttgt
     4921 gtggtcttcg atcttgtgtg cacatgttca atttattaaa gaaaagaaac ggaacactac
     4981 acaaagatat aaagatcttg ctttgttggt gttttttact tcaattgctt tcagcttgtt
     5041 attcgaaagc acgacacgct ttattccttt tttattggtt atctggtttg tattcttaaa
     5101 ttttgtatat aaaagaataa gcaatagaaa tatcagttag gcccagatac attttgcaaa
     5161 acgaattatt tcagaccccc ctgaaataat cgatacgcct gaaaaaactt ccctgcgtat
     5221 aataacagta tcaattaaac aggaggggat aggatgaact ggtacagatt gacggtagaa
     5281 gatgtattga aaaactatca aacatcaaca gaaggcttgt cgcaagaaga acgacagaaa
     5341 cgcctgactg atcaaggata taatgaaata aaagcaaggc agcagacaaa acgatggaaa
     5401 aaaatagcaa agcattttac tgatctgctg atgatcgtgt tgatcattgc ctcttttttg
     5461 aaatttgctt ctagtgaata tattgaagga agtattattt tattcgtagt gatcgtcaat
     5521 ggactcgtta gttactggca agaaagaaaa gcggaagaat cattgaatgg tttgaagcag
     5581 ctgatgggac aagaagcgat agtactatca aacgggatgc aagaaaaaat ccctgcgaaa
     5641 gaactggtaa aaggagatgt cattgtctta cgtgccggag atgtcgttcc agcagatatc
     5701 cgattaatcg aagcacatga tttattagtg gaagaatcga ttttgacggg agaatcagaa
     5761 gcatctgaaa aaagtcatgc cgttttgaca gaagaagaat cgatcggcga ccagaaaaat
     5821 atgggttttt caggaacgct tgtacaatct ggttctgcag tcggtgtcgt tgtagaaaca
     5881 ggaaacacga cagaaatcgg taaaatcaat caagcattgc aatcggtcga acaacaaacg
     5941 acgcctctga ttaaaaaaat caaccgatta aacaaacaaa tttttcaagg cattctttgt
     6001 ttgagcctat tcttagttat ttttacgaca tttcgatatg gtatggattg gcatattctt
     6061 ctttcggcta cgattgcttt ggtggtgtca atggtacccg aaggattgcc agctgttttg
     6121 accatgattc tatccgttgg agtacatgaa atggcaaaag aaaaggcgat catcaaagga
     6181 cttccttcgg tagaaacatt aggttctatg acagtgatct gttcagataa gacaggaaca
     6241 ttgacaaaaa atgaaatgac agttgtggat gtagctgcaa aagaagaagc ctgcgtgttg
     6301 tccattatga aaaactgtca ggaattaaaa acaaaagaag aacagaaaac agaaaattta
     6361 agtggcaatc cgacagaagt tgcgctgatt cgacacacag aaacagccaa tctacctttg
     6421 aaaaaaatag aagcaaagat tccgttcagt tctgaataca aatatatggc aacgatgcat
     6481 gcggaggaaa aaggagcggt gatttacgtc aaaggtgcac cagaagtatt atttgctaaa
     6541 tcaactcttt cttctgcaga acaagaagca tggagtcaga cagctgcaga atttgcgaga
     6601 aaaggtcagc gtgttttagg atttgcttat aaaaaagtag attcgaaaca ggaactcacg
     6661 catgagactt taacccaatt aacttttgca gggatcgccg gattgatcga tccgccaaaa
     6721 gaaagtgcag tcaaagctgt aaaggaatgc caacaagcag ggatctcagt gaaaatgatt
     6781 acaggggatc acaaagacac agcaaaagcg attgcggaac aaattggctt aaaacatact
     6841 gccaaagttt tagaagggat cgatttggat cttatgtctg atgaagagtt gattcagcaa
     6901 gtgccaatag tcgatgtctt tgctcgaacg acaccagaac ataaactgcg aattgttaaa
     6961 gctttgcaga aaaatggaga aatcgtcgga atgaccggag acggcgtaaa tgatgcacct
     7021 gctttgaaaa gatccgatgt aggaattgct atgggaatca aaggtagtga agtaagcaaa
     7081 caggcagctg atatggtttt aggagatgat aatttccata cgattgcaaa agccgtaaaa
     7141 gagggccggc ggattttgga taatttgcaa aaaaccatca atttcttctt gccaactgca
     7201 ttagctcaag gattgatctt gatttgggca cttatgctga atcgcccgct acctttgtcc
     7261 ccagtacaga ttttatgggt caatatggta acgacaatca ctttatctta tgcactaggg
     7321 ttcgagtcgc cagatccaga aatcatgaag cgcccaccaa gagatccaaa gcaaggaatc
     7381 ctatctggtt atcatttgtt tcggatcatc tatgtctccc tactgatcat ggttcctgcc
     7441 tatttattgg ctatgcagtt tgaagggcaa agcttacagc aaaccattct tctgcaaaat
     7501 atcgtcttag ctcaagctgt ttacatgatc aattgcagag agttgtccaa gccgtcattg
     7561 aaccaaggtc ttttgcaaaa caaagcgctt tttctttcat taggtatcct tgctttattg
     7621 caagggatgg ttatttttct accagtcggc cagcagctga tcggtacagt aagtttaacg
     7681 atgacacaac agttattgat tggagcaaat gtgattcttc tattcttagt tgtagaaata
     7741 gaaaaaggga tcatgaacaa actgtttcgc aaaaaagaaa aaacagctag agaatacagt
     7801 cgctagccgt tactataaaa aagttttgaa agtgagttca gtcaaacgat tgagctcatt
     7861 tttcgttgga atagaagaaa tgtatacaat agggatatct agagaatcta gagggaaatt
     7921 ggaaatcaag atatctgttt tttcaaaaga aatagtggaa agatcggtta gttcgatagg
     7981 taagaagcag acacgttttc ctaagtaatc ttttaattcc tgctgcaaga acgccttcca
     8041 tgaaggttct ccttggaaaa taaaatagac attgaacaaa ttcggtttga tagaaaaaat
     8101 cgtttgttgg atcagtagag acaagagttg gagaaagtaa tttggttcat tgatttctat
     8161 ttcttttttt agatcgttca gtaaattctc tttctgttga tacaagtgtg catattgctg
     8221 atcatatgtt tctaaaaaac gatggtattg acggtccaat gcttcaatca atatcggcga
     8281 ttcatgatat tttaatatga ggagagccaa gttatcagtc agagatgttt tttttagttg
     8341 atcaagagac agctctgaag ctagttcctc tacaaacgtt tcgaggacct ctaaaaatgg
     8401 agaatgatgc aggcagcgag cggtttcttg tccatagtta ttgttgtaat tccaactttc
     8461 cagaaagcag aaagaagcaa aagaaagctc agtgtcttta agataaatac cttccgttaa
     8521 atacaatttt ttcaatgcag agtcatacag ggaggagagt gtgctgttgg tatggataga
     8581 agaatctaat cggcaattcg cttttatacg gatcgtattg ataaagaacc aacatgttcc
     8641 gaaaatctct tctgtttcaa ccgctagttc agtttgactg aggtttctta aaaattgaaa
     8701 ataatgggat tcatggatcg aataatcctc gaaaaaatag ttgttatgag tgaaaggaat
     8761 cagcaatcga tgataaaaag tacgaatcgc acg
//
LOCUS       DADGHT010000109         8604 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.111, whole genome shotgun sequence.
ACCESSION   DADGHT010000109 DADGHT010000000
VERSION     DADGHT010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.111"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(132..1085)
                     /gene="menA"
                     /locus_tag="JX887_002455"
     CDS             complement(132..1085)
                     /gene="menA"
                     /locus_tag="JX887_002455"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAX1258394.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1098..2201)
                     /locus_tag="JX887_002456"
     CDS             complement(1098..2201)
                     /locus_tag="JX887_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAX1258395.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2291..3226)
                     /locus_tag="JX887_002457"
     CDS             complement(2291..3226)
                     /locus_tag="JX887_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAX1258396.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3528..5462
                     /locus_tag="JX887_002458"
     CDS             3528..5462
                     /locus_tag="JX887_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAX1258397.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5919..6335
                     /locus_tag="JX887_002459"
     CDS             5919..6335
                     /locus_tag="JX887_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAX1258398.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6349..6915
                     /locus_tag="JX887_002460"
     CDS             6349..6915
                     /locus_tag="JX887_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAX1258399.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6938..7924
                     /locus_tag="JX887_002461"
     CDS             6938..7924
                     /locus_tag="JX887_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAX1258400.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8079..>8604)
                     /gene="scm"
                     /locus_tag="JX887_002462"
     CDS             complement(8079..>8604)
                     /gene="scm"
                     /locus_tag="JX887_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAX1258401.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
BASE COUNT         2529 a         1655 c         1753 g         2667 t
ORIGIN      
        1 tgataaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat
       61 aaggagctat ttttatttgg ctgttcttat tacttgatgc agggcagttt tttcacaacc
      121 tcttcatgct gttaaatggc ttgcataatg attgttagta atagccccaa tacataactg
      181 gcattgaata agaccatatt tttgatggaa tagctgaaac tgataggctg gggtaacgtt
      241 tgcttgaatt gatccaaatg cttcttcaca attggcaagg tcaagaaggt gaccaagatc
      301 ggccattcat agataccgct caacaacccc attaaaatca cgaaatagca agcatacatc
      361 aatagctgga ataagactgt tcccgcagga cgtccgatat aaaaaactag tgtatagcga
      421 tgattttcaa tatcacggtc aagatcccgc aaattattag ccaacatgat attggcaatc
      481 gtaaacacca agggtaagga agctaatacg attgctgcta tagcccaaag atttcctacc
      541 aaagcaaatt gtccagatga aaagttgact gtcagatcat agacatctga accgaatgta
      601 ttgacataaa cgaccatggc aaaaattcca aggcccatag tcaccccact gaaaatttcc
      661 cctaaaggca ttcgagataa aggaatcggt ccgaatgtat agaatactcc aataaaacaa
      721 cagataaatc ccatcaaaag taaaagccaa cccgtattga tcgttagaat aacgccgata
      781 acaaaaacaa atgcaatcat agctaaaatc atgtttcgaa tcaatacagg agatagattt
      841 ctgcggccaa tgacattttc ttcatactta tatacttcag aatgagcctt ttcataatcc
      901 atgtaattat tgatagcggt agtcgctaaa tcaaaaacta gcattccaat aaaaaataaa
      961 aaagtgttta gccaatgtat ctcatgaaaa aaagcgatag agaataatac ccctaccgca
     1021 aaaggaaata cactagccac ctttgttcgt atttcaacta cttctaaaaa gatttttagt
     1081 gtcatggttc gtactcctta ttttagttca gaacggtcac ccatcgtgta atgggagtcc
     1141 tccgataatt tgaaggtgtc tttgattgga tcggtcacat atactttatc gtcttttgtc
     1201 acgaagatcg cttccgtccc gttattcaat tcgctttcga cgtattccag tccttttttc
     1261 acacccattg aaaagactgc tgtagacaac ccgtcaccat caattgattt atctgttatg
     1321 atcgtgacac ttgcgatatc attgtcgaac ggataacccg tttttggatc aaacaaatga
     1381 tggtattttt tgccatctac ttctaaataa cgctcgtaaa ttccagaggt aactaatgtt
     1441 ttgttccgtt ctttaataga acctaaaaca gatccgcgag ccatgttcgg atcttggatg
     1501 ccgactgtcc agtcttggtt ttcgcctctt gggctgtggc ctaagacata gacattaccg
     1561 cccaagtcaa cgatggcagt ggtcactcct tgttttttca agactttcac tacttcgtcc
     1621 gtaatgtaac ctttggcgat tgcacctaaa tcgatgatca ttcctttttc ttttagataa
     1681 acagtttttt ctttgtcatt tagttcgatc ttatgataat ccactaattt caatgcctga
     1741 tcgatttctt cttgggaagg ttttctggcg tcatcaaaac cgattcgcca taattgtgtg
     1801 attgcaccaa tcgccatatc gaatccgcct tgagaatctt ggctatattc gtaggcccgc
     1861 ttgactaacg tgtagacgtc atcagaaact tttactggtt tgatcccagc ttgctcattc
     1921 acttcatcga tctcagaacc tttttgattg atcgtgattt tatcaccaag ttcttttact
     1981 cgatcgaagg caggtttcaa tgctgattct ttgccttcat catacacacg gatacgaacg
     2041 taagtcccta acaagaactg ttcatcagaa tatggatctt tcaatatctt ggtagctgct
     2101 gaactttcag tggttgtttt atttgctgag ttgctgcagc cagttagcac cataaaagag
     2161 atgcccagtg tgattaagga aaatagtagt tttttccgca tctttttcct ctcttcattt
     2221 tgaaaggtga gacgactgcc taatctggct atcgtcccac cctccaactt ttattagtat
     2281 gattatgtga ttatttttct gttacgatat tatctacttc gattgtttga gtgtcgcctt
     2341 tttcagctgc attcactaat tgttgtgcgt acatgatgaa tgaatgtgag ctgtgtgtag
     2401 cacctgtaac aacttctaca ttagcaggtg agccatcttc ttcgcccatt gctttgacga
     2461 attcgtcgtt cagagtaggg atgtaagttt ttggttctgt accgcttttt gctttcatat
     2521 tttcattata ttctgtatca tcttgttttg atttaccgtc tttgtcgata taatcaaagt
     2581 ttgattcagt tactttgccg ccagcaactg tcatttcgaa ttgcacacgg tagccgttag
     2641 agtagttctt ttcttcaagc ttgtaagtgc cgtctttcaa atcagcacca ttgtcgattt
     2701 cgattgtatc tgtgttacca gcttgagcag cttggatcaa ttgttgtgcg tagttttgga
     2761 agctttcaga tgagtgagta gctccagtta cgacttccac accgcttgcg ctttgtgctt
     2821 ttaagaattg gtcattcaac tcaggaatgt atttttctgg gtttgtgcca gattttgctt
     2881 ccatgttttt gttgtattct gcatcttttg tttttgattc gccgttttca ttgacgttat
     2941 catattttga ttcagtgatt ttgccgtctt ttacaaccat ttcaaagact gcacggtaac
     3001 catttgaata atttttttct tctaatttat atgtgccgtc ttgcaaatct ccgccagcta
     3061 caacttttgc agatgattct gttgtgcttt ttgcagtcga agattgtgct gtagatgatt
     3121 cagaagaaga gtttgagctt ccgttgtcat ctgcgccgca agcgcctaac actagagctg
     3181 aaaatgctaa tacggcaaat ccagttacaa aacgtttttt cttcatttta ataccccacc
     3241 attccatttc tagtccacaa tttttctttg tgattcatta tacattctaa tctttttagc
     3301 ctataagtca actatttttg ataaataacc catgtaatat ttcaaacgtt ttctttcagc
     3361 aaatttcgtg aaaaaacgct ttattttaaa atttgaaaaa aatccaaaag gagttagaca
     3421 aaagaacaga acatctatat aatatatgga gattgtgtaa taagtatcaa actaaaagaa
     3481 ttatcatata ttcattatat agatagtcta taaggagcgg atgatcaatg gcaaagcaaa
     3541 atattgtcgt tgtaggagca ggatatgccg gtgtttcagc tacaaaatac ttggcaaaga
     3601 aactgaaaaa agaagatgta gcaattactc tgatcgatcg tcattcgtac catactatga
     3661 tgaccgagtt gcatgaagta gctggcggac gtgtagaacc agaagcaatc caatacgatc
     3721 tgcagcattt gtttgctcgt caaaagaatg tacaacttgt cacagacact gtaatcggta
     3781 tcgataaaga acgaaaaatc gtcaagacca aattaggttc ctatcctttt gatcagctga
     3841 tccttggaat gggcggagag ccgaatgact ttggtacacc tggtgtcaaa gcacacggat
     3901 tcaccctttg gtcatttgaa gattctgtaa ggattcggga acatattgag aagacagtag
     3961 caaaagctgc attggaacca gatgatgaac tgcgtaaagc catgctgact ttcgttgtct
     4021 gtggttctgg atttaccggt attgaaatga ttggggaact gatcgactgg aaaaatcgcc
     4081 tagccaaaga ttataaatta gatccaaacg aaatcacact gatggtcgta gaggcaatgc
     4141 cgacgatctt gaatatgttg gatcgaaatg atgctgcaaa agctgaacgc tatttgcgta
     4201 agcacaacgt ggaattatta ttgaatgcac caatcgtaga agtggctgct gatcatatca
     4261 aattgaaaga cggacgcaac attccgactc acacactgat ttggacagct ggtgtcaaag
     4321 gaacttctga cgctgctgac tttggattag aatcagcacg cggacagcgg ttgatcgcca
     4381 atgaatatat gcaggcaaaa ggctacgaag ataaaaacat ctatatcatt ggtgatttag
     4441 tcttttatga agaattccca ggaacaccga caccgcagat cgttcaagct gctgaacaaa
     4501 caggacacac agccgcagcg aatatcgtgg cttcgatcaa aggcggagaa aagcataaat
     4561 ttaaaggaaa ctatcaagga tttatggttt ctattggtgc caaatggggg gtagctaacc
     4621 tatttgataa gatccattta agcggatttt tagctatcgt aatgaaacat atcgtgaatt
     4681 tgaaatactt ctttgatatt cgttctggtt attatatgtt ccaatattta atgcatgagt
     4741 ttttccatat caaagatgat cgcaacgtga ctcgaggaca ttcttctcgt tacggcaatg
     4801 tcttatggag tgtgccactt cgtattttct atggtttagt ttggttcgtt gaagcttcca
     4861 aaaaaatcat tgggaatggt gaagtgttca aaccaagtac ttggtttggt gaaggatcat
     4921 ggttcactgg aaacagtgtg ttcccttgga catgggaata caatgtaaca gatgttgcca
     4981 gtggtgcttc tgctgctggt gatgcaacca cagctgccag cggagcaggg gcaagtgccg
     5041 gagaagcagc gactcaagct gcacattttg gtttgagtta tgcatacggt gaagaaccaa
     5101 tggctgtgat tgagaagtca ccagactggt tcacaaagat catgcaagtg atcatgccaa
     5161 acaatgatgt agcaatgttc ttccaaaaat tcatggtatt ctttgaaatt gccttggcat
     5221 tagcattgat tgctggatta ttcacatggc tatgcagtgc gacaacgatt gtattggtga
     5281 tcacgttctg cttatcaggc atgttttact gggtaaacat ttggttcatt tttgttgctt
     5341 tcgcattgat gaacggttcc ggacgtgcga ttgggttgga tcgctgggta attccatggc
     5401 tacaacgtac actaggtaat tggtggtacg gtagaccaag ttcccagtac ggcaagaaat
     5461 aaatagataa agaacgttat ttgaatgcaa gatttcaata gaaaggggct gagacaaacc
     5521 gtcacagcct cctttttatg taaaattaaa ggaataagat gcccgagata agcctccatg
     5581 agcaagacac aggtgtcaca acctctgtta caacctcttg ttataaacgg tgttccagaa
     5641 gtagcttctt cgaaaaataa gccgaaattt cacaaaaact tgaaaagtaa ttttcgtaaa
     5701 ttccttctta tttcttgaag ttgcccactt ctgtcacaac ctcttgttat aaacggtgtt
     5761 ccacctgctg cttctcggta ataagcccaa agaattagaa aacatggaaa gctgttttct
     5821 attcttcgtt cttattactc aaagcaagac acaggtgtca caacctcttg tttttatgct
     5881 aaaattgggt gagttaatct ggaaaaagga gaacaaaaat gagccttaaa gaatttgctg
     5941 aaaaaagtct gctcaaacct tgggatgttt ttattatttt gcttttgact gttctttctt
     6001 ttttaccagt catgattttt ggtcttcagc aaaacaccgc aacagcagaa aaagaagcgg
     6061 tactgcgtgt ggatggcaca gaaatcaaaa cattcccttt gatggctgga gaagagagca
     6121 acacatatac ttacaaagat gaacacggag attataactt gatcgagata gatggcgatc
     6181 gagtacggat aaaagaagca gattgcgatg accagatctg cgtacgtcga ggctgggcaa
     6241 cgaaaaatgg cgaaaccatc gtctgtttgc cacataaatt agtgatcgaa gtccgttcaa
     6301 cagatggagg tgacgaagac agtctgattt attagacctt tacacaccat gagtaaatta
     6361 caaaaaatga tttatatttc gctacttgtt gcacaaggag tgatcattgg tttattggaa
     6421 aatatgatcc cttatccttt ttcttttgcg cctggtgcaa aactaggctt agccaatcta
     6481 atcacgatcg ttgccatttt taccatgaaa aaacaagaca gcttcttact actttggcta
     6541 cgactattcc tgactacttt gctaggcgga acgatttcca cattccttta tagtatgagt
     6601 ggtgctttgc ttagttattt tggaatgtta ttggtcaagc aattaggacc aaaacgtgtc
     6661 agtatcatcg gaattagtgc ggccggcggt ttcatgcata atgtcggaca gcttttgatg
     6721 gcttctttca ttgcacaatc atggacagtc atgttgtact tgccagtcct ttcagtttta
     6781 gggattttat cagggattgc aatcgggatc gcagcgaatt atcttttacg acatgtgcag
     6841 acacttcaac gattccaaaa agattatgag cagggaacca aacaaaaatg gagcccaatg
     6901 tttaccaaaa aataatcgtc acacaaggag tttttttatg aagctacatc caatgtggga
     6961 aaactatcct gctttaagta aagaattgac agaaacacta aaacggatgg aagaaactgt
     7021 ccgcctgaaa aacaaacctg tcgaacaagc aatcaaagaa acgatccatg ccggcggaaa
     7081 gctgttgcgt cctgcctatc agctattgtt ctcacaattt ggaccagagc aagatcgaga
     7141 caaagccatc gctttggcag cttctatcga aatgctccat acggccacac tgatccatga
     7201 tgatatcgtt gatgaagcgg atctgcgacg tggtcagcct aatatccgta gtcagtttgg
     7261 taatgtcgtt tctgtctatg caggagacta tttatttgtc tgctgtttta aactattgtc
     7321 tgattactcc acttccttga aaagtctcca attgaattct cgcagtatgg aaaaagtatt
     7381 gaatggcgaa ttagggcaga tggatgatcg ctataattat gaactttctg taaaagaata
     7441 tttggaaaat atttcaggta agacagctga actgttccaa ttaagttgtt ctgttggcgc
     7501 ttttgaaagt ggaacaagcg agcgcttcgc aaaaaaagca ggagatatcg gactttctat
     7561 cgggatggcc tttcagatta tcgatgatat tttagattat acaaaagaga gccaggaaat
     7621 cggcaaacct gtactagaag acatgcgtca aggggtctat tctttaccgt tgatctactc
     7681 tttgcaaaaa aacaaaccaa agctactacc ttatttagag aagaaagcgg caatgacaga
     7741 agaagatgtc gacgccgtac gcaaaatcgt tgaacataca ggaggcgtgg aagaagctag
     7801 gaagttagcg gcctcttaca cagaaaaggc tttgaaggaa ataaagaaat tacctgccac
     7861 ctctcttcga acaaaagaga atctcttttc ccttacccaa ctgattttgg atcgcaaaga
     7921 ctgaataggg aaaggttcga tacgtaaata aatttctcag aaggaaatct acgtgttttt
     7981 tgacaaattg aattgtagtt cttgtattta tgataaaaag caaaaataaa gagcaacgtc
     8041 cgttagcgac gttgctcttt tttatcttga atattttttt accttttcga tttcttataa
     8101 ctcataaaag tgattcttaa accgattaca agtaatataa cgcctgcgag tgttatccaa
     8161 ttattcgatt gacttccagt tttaggaagt gctctttttg atttgtttcc attgtcattg
     8221 cttgttttat tagttaagtt aaagttcgtc ctgttatccg aacttgtttt tgagaaggag
     8281 acacttgcat gacgtgtatc gcttgtggta gacgacgtgt ctgtactatc gcttgaagtt
     8341 gatgaatctg agctatcact tgtggtagag gatgtatctg tactgtcact tgaagctgac
     8401 gtgtccgtgc tatcacttgt agtggtagat gaatctgagc tatcacttgt ggtagaggta
     8461 gtatctgtac tgtcacttga agctgacgtg tccgtgctat cacttgtggt agaggtagta
     8521 tctgtactgt cacttgaagc tgatgtgtcc gtgctatcac ttgtggtaga ggtagtatct
     8581 gtactgtcgc ttgaagctga cgtg
//
LOCUS       DADGHT010000110         8493 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.112, whole genome shotgun sequence.
ACCESSION   DADGHT010000110 DADGHT010000000
VERSION     DADGHT010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.112"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..173)
                     /locus_tag="JX887_002463"
     CDS             complement(<1..173)
                     /locus_tag="JX887_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009325336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1258402.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="JX887_002464"
     CDS             complement(593..1714)
                     /locus_tag="JX887_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HAX1258403.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /locus_tag="JX887_002465"
     CDS             2042..3451
                     /locus_tag="JX887_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HAX1258404.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /locus_tag="JX887_002466"
     CDS             3448..4176
                     /locus_tag="JX887_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1258405.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="JX887_002467"
     CDS             complement(4304..5215)
                     /locus_tag="JX887_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1258406.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="JX887_002468"
     CDS             complement(5232..6239)
                     /locus_tag="JX887_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAX1258407.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSIPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="JX887_002469"
     CDS             complement(6236..8365)
                     /locus_tag="JX887_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAX1258408.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8477)
                     /locus_tag="JX887_002470"
     CDS             complement(8370..8477)
                     /locus_tag="JX887_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258409.1"
                     /translation="MQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2600 a         1727 c         1486 g         2680 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggaattga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg ttt
//
LOCUS       DADGHT010000111         8249 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.113, whole genome shotgun sequence.
ACCESSION   DADGHT010000111 DADGHT010000000
VERSION     DADGHT010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.113"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(204..1652)
                     /gene="cls"
                     /locus_tag="JX887_002471"
     CDS             complement(204..1652)
                     /gene="cls"
                     /locus_tag="JX887_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAX1258410.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1804..2697)
                     /locus_tag="JX887_002472"
     CDS             complement(1804..2697)
                     /locus_tag="JX887_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1258411.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="JX887_002473"
     CDS             complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="JX887_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAX1258412.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3472..4573)
                     /gene="prfB"
                     /locus_tag="JX887_002474"
     CDS             complement(join(3472..4509,4511..4573))
                     /gene="prfB"
                     /locus_tag="JX887_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAX1258413.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4699..7233)
                     /gene="secA"
                     /locus_tag="JX887_002475"
     CDS             complement(4699..7233)
                     /gene="secA"
                     /locus_tag="JX887_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAX1258414.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            complement(7455..8006)
                     /gene="raiA"
                     /locus_tag="JX887_002476"
     CDS             complement(7455..8006)
                     /gene="raiA"
                     /locus_tag="JX887_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAX1258415.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(8134..>8249)
                     /locus_tag="JX887_002477"
     CDS             complement(8134..>8249)
                     /locus_tag="JX887_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAX1258416.1"
                     /translation="KILIIDDVYTTGQTLFHAADCLQNAQPKIIRTISLAR"
BASE COUNT         2200 a         1816 c         1440 g         2793 t
ORIGIN      
        1 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
       61 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      121 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      181 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      241 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      301 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      361 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      421 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      481 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      541 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      601 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      661 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      721 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      781 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      841 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
      901 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
      961 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1021 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1081 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1141 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1201 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1261 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1321 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1381 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1441 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1501 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1561 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1621 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1681 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1741 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1801 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1861 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     1921 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     1981 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2041 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2101 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2161 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2221 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2281 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2341 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2401 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2461 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2521 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2581 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2641 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2701 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2761 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2821 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     2881 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     2941 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3001 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3061 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3121 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3181 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3241 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3301 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3361 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3421 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3481 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3541 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3601 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3661 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3721 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3781 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3841 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     3901 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     3961 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4021 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4081 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4141 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4201 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4261 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4321 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4381 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4441 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4501 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4561 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4621 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4681 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4741 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4801 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4861 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     4921 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     4981 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5041 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5101 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5161 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5221 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5281 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5341 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5401 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5461 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5521 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5581 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5641 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5701 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5761 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5821 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     5881 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     5941 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6001 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6061 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6121 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6181 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6241 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6301 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6361 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6421 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6481 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6541 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6601 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6661 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6721 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6781 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6841 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     6901 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     6961 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7021 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7081 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7141 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7201 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7261 tgtattatcc agactatgta gactttactt ttcattttat cattagttat agataattga
     7321 aatatcttaa gcgtattaaa gtaagaactt cataatttat tcatatttca tctaaaagag
     7381 gaggaaactc aaaaaaactt gcggcagctg tcagtagctg ctgcaagttt tcgttgttat
     7441 ttaagtaagg ctgatcagtc tgtttcaatc agtccgtatt ttccatcttt acggcggtaa
     7501 acgatacttg taccatttgt ttctgcatct tcaaaaataa agaagttatg tcccagcatg
     7561 ttcatttgta agactgcttc ttcactatcc attggtttca atgaaaggcg tttcgtacgt
     7621 acgatatcta attcagaatc attttcgttt tcgtcctctt cattgaataa agcagcagca
     7681 tctgcagtat tcatgcccgt ttcacgggat ttacgattaa tttttgtttt gaatttgcgg
     7741 atttggcgtt ccaatttgtc aacaaccaaa tcgatacttg cgtataaatc tggagaagtt
     7801 tcttcggcac gtaatacaag ataaggtaat gggatcgtta cttccacttt tgctgttttt
     7861 tctgtataaa cttttaagtt cacatgcgcc gttgcatcgg gtgcgtcact gaaatagcgt
     7921 tctagtttgc ctactttttt ctcaacgtag tcgcgaatcg cttcagttac ttcgatattt
     7981 tcgccgcgta cattatatct aaacataaaa attacccctt tcgtctacca caatcaagaa
     8041 ggagaaggac cactctttcc ctcttcttaa ttctattata tcgaactcta ggttatttgc
     8101 aaattaaatc gctatcaaat ttccacatct gattcatctt gccaaagaaa tggttcggat
     8161 gattttcggc tgtgcgttct gcaagcaatc tgctgcatga aaaagcgtct gtcctgttgt
     8221 atagacatcg tcaataatca atatttttt
//
LOCUS       DADGHT010000112         8163 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.114, whole genome shotgun sequence.
ACCESSION   DADGHT010000112 DADGHT010000000
VERSION     DADGHT010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.114"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..2909
                     /locus_tag="JX887_002478"
     CDS             <1..2909
                     /locus_tag="JX887_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAX1258417.1"
                     /translation="ETSVTFSFEHQQMSYEIERKPEQVLAKRKGNGTKKQAAKVTLTI
                     FDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGEFRNFLVSSSSDKETVL
                     RHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFVLVKEEEPAAGFEAVLA
                     QWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKKSYEEKTILINKQKELA
                     AQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQKSSEQTKKLAMTTQNYE
                     EWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQDAEQLTISLDKEELNAE
                     KLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEKQQEIEKQKAKDTGSLA
                     QIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARLQLFLRPGEPCLVCGST
                     EHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSEAHENNLQQQLSDLEQK
                     IMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSLDRRKSKMANARIELEE
                     IRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQDTDSNCLEEEIRRLEKQ
                     LEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEKIEKEQERIAKKLESQS
                     YFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQLENIQLTETFPDTEEIS
                     QQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQTKLDELTQLQQLSQTF
                     NGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFELADTIGSYRGKTGLEIN
                     IYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGVAIDALFIDEGFGSLDE
                     EALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTEGSGQSKIRYQLG"
     gene            2928..6122
                     /locus_tag="JX887_002479"
     CDS             2928..6122
                     /locus_tag="JX887_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAX1258418.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(6268..6975)
                     /locus_tag="JX887_002480"
     CDS             complement(6268..6975)
                     /locus_tag="JX887_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAX1258419.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            7740..8138
                     /gene="spxA"
                     /locus_tag="JX887_002481"
     CDS             7740..8138
                     /gene="spxA"
                     /locus_tag="JX887_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAX1258420.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         2986 a         1384 c         1638 g         2155 t
ORIGIN      
        1 aagaaacaag cgtgactttt tcttttgaac atcagcagat gagctatgaa atcgaacgaa
       61 aaccagaaca agttttagca aaacgaaaag gaaacggaac aaaaaaacag gcagccaaag
      121 taacgttgac catttttgat gggaaaggaa aagaaataaa acaaatcaca aaacgtacag
      181 aagcagatca gttgatcaga gaactgatga atctcgatgc gaaacagttt tctcaaatcg
      241 ttttactacc ccaaggagaa ttccgtaatt ttttggtttc atcaagcagt gataaagaga
      301 ctgttttacg tcatttattc ggtactcaat ttttccaaca gttcaatgag cgattaaaag
      361 aaaaagcaaa acaacagcaa caaaaattgg atcatttaga gcaagagctg catcttctgc
      421 aaaaaaggtt tgttttagtc aaagaagagg aaccagcagc agggtttgaa gccgttttag
      481 cccaatggac aaaccatcag gcaatactcg aaaaacaaat cacggaagaa aaagaagctc
      541 taacggaact tcaggaaaaa caaaagcaac tagaaaattc ctactatcgt tttgaaagct
      601 tgaaaaaaag ttatgaagaa aaaacgatat taataaacaa gcaaaaggaa ttagctgctc
      661 aaaaagacga aatagaggaa aagaaacgat ggattgggta ttatgaattt acgcaacgat
      721 tagtcgaacc aatccagcgc ctacaagaaa taaaagttga aaaaatagaa ctgtcacaaa
      781 aaagtagtga gcaaacaaag aaactagcga tgactacgca gaattatgaa gagtggcaaa
      841 aaaatgaagc aaaccgcgta cgccgacaaa caaaaatcaa agaagctgct caaaaactgc
      901 aaaacaaaca gatgatggtg ccaattgtcg aatccttacg tagtaaaaaa caagacgcag
      961 aacaattaac aatttcattg gataaagaag aattgaatgc cgagaagctg tatcaaaatc
     1021 tcgctatcta tcaggaaaga actcgaattc ttcaagaaaa tttactggat caggaaaaac
     1081 tgcaagaaga tcgtcttgct tttggacagt taaaatatct agatgaaaag cagcaagaaa
     1141 tagaaaaaca aaaagcaaaa gacactgggt cgctcgcaca gataagagaa gaactcaaaa
     1201 aagcaactga agaaataaca aaaaatagtc agctattgaa agaacagaca gaacaagcag
     1261 aacagctgaa aagccaatgg gcaaagcagc aaattgctcg tcttcagctt tttttgcgtc
     1321 caggggagcc atgtcttgtt tgtggatcaa cggaacaccc catacaacaa ttaaaacacg
     1381 aacagccaaa taaggaagat atcttaaaag tagaacaaca actggcagaa gctgagtctg
     1441 ctgtagaaag aactcagcaa atcattgcca aaagtgaagc acatgaaaat aatcttcaac
     1501 aacaattatc agatttagaa caaaaaatca tggcaacgaa tatacaattg gctgaacaag
     1561 aagaacactt gcaacaggct ttgaaaaagg catttcctga gataacagaa caaaaaacaa
     1621 aaacaactct tgtagtaatc gaacaatctt tagatagacg aaaaagcaag atggccaatg
     1681 caagaataga gctggaagaa ataagacaac aagcagaaaa gctcgaacaa caattagctg
     1741 tctacaaaca gcagcagaca gaaaaaaata atcagctcca gcaactgcaa ggagaaatca
     1801 aaagtttaga acaacaattg caagatacgg atagtaactg tttagaagag gagatacgac
     1861 gacttgaaaa acagttagaa gaagactcga atcaactagc tgttgagcag aaagcaggag
     1921 tgcaattgtt gcaagatctt catacgcttc ggacacagct tgatcttcaa catgaacaaa
     1981 tagaaaaaat agatgaaaaa atagaaaagg aacaagaaag aatagctaaa aagttagaaa
     2041 gccagtcgta tttttcaaca attgaagaaa tctgtgcatt tgcacaacag caagcacaat
     2101 ataaagaaaa ccaacgtaca gttacttctt atcatgaaga gcaattagtg acagctgacc
     2161 ggctgcgtca attagaaaat atccagctaa ctgagacatt cccagataca gaagagatca
     2221 gccaacagtt agaagaaata agacgtatga tcgaaataaa gcaagaaaag atatacggtt
     2281 tacaagaaca aaaaattagt aatcaaaaaa tctacgatga atgtctttcg atttatcaca
     2341 caagccagac gaaattagat gagcttacgc aattacagca gctttcgcaa acattcaacg
     2401 gagaaaatcc taagaagact agtttggaac ggtatgtgct tcaggtttat cttcaagaag
     2461 tgttacaagt agcaaatgat catctccaac gtttaacgaa aaatcgttat caatttgagc
     2521 tagcggatac cattggcagt tatcgaggga aaaccggatt agaaatcaat atctatgatg
     2581 atcaggcagg tatgtctcga agtgcgcata ccctgtctgg cggtgagagt tttattgcag
     2641 cactttcttt agcattagct cttgccgatg tgatccagac acaagctggt ggtgtagcaa
     2701 tcgatgcatt gtttattgat gaaggatttg ggtcattaga tgaagaagct ttggaaatgg
     2761 caatggaagc tttagaaacg atcgaaagtg aaggaagaat gatcggcatc attagtcatg
     2821 taagagaatt gaaagaacga gtattacaac aaataagaat tgatacagaa ggtagcggac
     2881 aaagcaaaat acgctatcaa cttggataaa aagggagatt ggtaactatg aaatggagta
     2941 ttccagaaaa agtcattgca cgtggacgtc aatacttgca agaaggccga gtgttatcgg
     3001 ttgtccctga ccaagaagaa aacgtgtggc atgcagaagt cttgggcagt gaattgtata
     3061 tggttgattt ggatggtaca gcaaaagaga tagattactg ccaatgtccc tattgggagg
     3121 aacataaata ttgtaagcat acagttgctg tggaacttta tttacggtcg aaaaatctat
     3181 ctcgtatcat gaaaaaagac cagccaatgc tagaaccggt aaaagcaaca agtgagggag
     3241 aaatcattgc aaaaggtttt tctcgtctaa aaacacaaaa caatcctcaa gcggtgcaac
     3301 ctttgattat tgaataccaa gtagaaacga ttgagactaa tcagtatcac ccagagcttt
     3361 ctattttggc actttacttg cgtatcggtt cattggcatc accgaaaaaa acatatatcg
     3421 taaaaaacat ctatgatttt ttacaagctt acacagaaaa agaaacttac actgttaata
     3481 aacagtacca gtttcgtcta gataaacggg cgtttcaaaa agaagatcaa aaaatactca
     3541 cgcatcttgc aggaagtgct cagacgcatc aattattagg tacgaacggc ttacaagtca
     3601 aaggaaaact agataaaaga tatctgcttc tcccagtaga acaagcccgc ttcctgttag
     3661 agcagatgaa tcagactaca cgtttgcatc tgcagataaa tgaacaaaac gatcaaggaa
     3721 tacaattttc cgatcaaaac aaacctttat cattcaaagt ggaaaaattt ggagaagatt
     3781 atttgctgca agcattgaat gattttgatt ttttctttat gcattatcag tggggagtta
     3841 tccaagggac attttattct ctgacgaaat atcaacaaac ggtttatcaa acttggaaac
     3901 aattgattcg ccgattggag aaaccagaag tagtgttcaa gaaaaaagaa ttaccgtctt
     3961 tgtttaaaga gattatccct ctgctgtcag agatcggcga cgtagctatt gcccctgcag
     4021 tagaagagga agtagcagat atccccgtcg aatttatttt ctttttccga aaagcaaaag
     4081 gaaaaatcca agctcgagtc gatttcgtct atggtgaagt catctattcg actgacccga
     4141 agcatgaggt ctcgacagaa caggcttttc aggtgttacg tgacacagta gaagagaaac
     4201 gagtacttga tctattcaga atgtatcgct accagaaaaa tgaaactggt tatgaacgtc
     4261 cattgccaag cggggaagaa ctatatgcct ttttccgcac agaactatct gtcttccgtc
     4321 agtttggtga agtcagactt ggaagaaaat tgcgagagtt gtatttagat gcgcataaac
     4381 atcaaccgaa aatcgaagta accgagaccg gttcatggct cgatattcga ttcgatgtga
     4441 cagggataga ggagcaagaa atcgatcatg tcctgcaaag cttgctgaga aatgatgctt
     4501 tttatacatt agaaaatggt caggttcttt cttttgattc agaagaattt caacaaacaa
     4561 gccaagtgtt gcaacaatta cgggaatcga tacgtacaga agaaggaacg atccatgtac
     4621 ctaaaaatca aggattgatc attcaaaatc aattggaaaa aagcaatgct acttttagtg
     4681 aatcgttcca aacgatggta caagatctca ttcatccaga aagataccag gcacagcttc
     4741 ccaaaggatt gaatgcaacg atgagagatt atcaaaagca aggttttcga tggttgaaga
     4801 tgttaggtca ttatcagttt ggcggtattt tagccgatga aatgggactt gggaaaacac
     4861 tacagacaat tgccttttta ctttcggaaa aagaagaacg gaaaagcttc tctgctttga
     4921 tcgtagcgcc tgcgagctta atttacaact ggcaggcaga ggtgagaaaa ttcgcccctt
     4981 ctttaagtat ccaagtaatc aatgggaata aaaaagaacg tgaagaatta ctggctaaag
     5041 acacagatat ccgagtgact tcttatgcca gcttaagaca ggatctagct aattatcagt
     5101 cgcaaaaaat tgattatttg attcttgatg aggcacaaat ggtcaaaaat agcagtacga
     5161 aaactgcaca agcattgaga gaattagctg tacctcagcg gtttgcactg agtgggacac
     5221 caatcgagaa taatttagaa gaattgtggt cattgtttgc aacgattatg ccaggatttt
     5281 tcccgactaa aacaaaattc agggaacttg ccgcagaaga aattgcgcaa atgattcgac
     5341 cgtttatttt acggcgagat aaacaaactg tgttgaaaga cttgccggaa aaaacagaga
     5401 tgaatctata ttctgcactt acagaagaac aaaaaactgt ttatttagct tacttgcgtc
     5461 aaatgcgtga agaaatcaca tcaatggatt ctgaagcatt caagaaaaac cggatcggga
     5521 tacttgctgg tctgacaaga ctgcgacaaa tttgctgcga tcctcgtctg tttattgaag
     5581 attaccaagg cggttccggc aagctcgaac aagtaaaaga tctactggta gctgccaaag
     5641 agaacaaacg aagagttttg ctgttttctc aatttacagg gatgctgact atcttgcaag
     5701 aagagttagc cgagctaggg atctcgacat tttatttaag aggcagtacg aaaccacaag
     5761 atcggttaag tatggtagac gcatttaatg ctggcgaaaa agatgttttt ctgatttcct
     5821 taaaggctgg gggaactgga ttgaatctca cgggagcaga tacggtcatc ttgtatgacc
     5881 tttggtggaa tcctgccatt gaagaacaag ctgctggacg tgcacatcgg atcggacaaa
     5941 aaaatgtggt agaagtgtgg cgtatgatct ctgaaggaac gattgaggaa cgcatggatt
     6001 cactccagca agaaaaacgc gaactgttcc aaaaagtgat ccaaggtaat gaagaacagt
     6061 tgacgaaact gactgaagaa gacatccgca tgattttaag tgtaggagaa atcgaggagt
     6121 aagagactcg aaaaagcgtt cagtaatggg taagaaagcc tttctaaaga agcgattgtt
     6181 tatttgattt aaaaaatagc aaggaggctg ggattccatt ttatcccagc ttccttgcta
     6241 tcattttttt atttctattt ttaaaggtta tacaaagatt gtcttcattg tctctaacag
     6301 ctgatcaaaa gaagaaatct cgatatcgca aattggagtc tgttcaattt tgcgttctcg
     6361 atggttgaac caaagcgctt gccagttagc actttttgca cctagaacat cattgtcgta
     6421 attatcgcca acgtataagg tctcttctgg aagcatatga aattctttct cagccagctg
     6481 aaaaatctct ttttctggtt tttggaaacc tgttgcttga gaaatgagca tattgcggga
     6541 aggaatccaa ttgttcaatt gaagttgctt cagttttttt gtctgatggt cagtcggccc
     6601 atttgtgata attcctaatg ggacattctt ttccttcaag aaatcgaggg tttttttgac
     6661 ctcctcatgc aagcagatat tatcaagttc ttcctcgtaa attttttgaa ataagaggcc
     6721 atcttcttcc gtaatatgag ggtagtctaa atcttttagt gattggctga tccgatgtgc
     6781 tcgcatatat tctagtgtcc aatctcctgc cattactttt gggaagtttt catcactatg
     6841 atggcggaac cggatatata gtggatgcat atctgcatct gaaacaagcg gaacgactct
     6901 tttgaccgcg tttcgaaatg gctgctgctg atcatacatc gtatcatcaa catcaaacac
     6961 aactgattta atcaaaattt tacacgcctt tcggttttca ttgatttttt cacaaatcct
     7021 tgactattgt aacagaaaaa attgtctaaa aaagctgata aataaaggtt tttcttacta
     7081 tatttctatt tccttgacag aataaggttt ttatatttca gtttttttca ctaaaaatcg
     7141 tgaaacacgt caataagttt gatgaacaaa ttaatcatta tggtagaagt cgattgattt
     7201 attttaatgc aatctctgtg gaattttcga aagatttatt tttttaatac agtctcaata
     7261 taactattca aacataaaat aacgttattt gatttatttg tttatagtaa attttattta
     7321 gtaatcattg ctttaaaata ctacgcttat ataacagaga aaataagcgt tataataaag
     7381 aacagtatta tttaaaatga cagaaaacat tactattaaa gaaataaaaa acataaaaaa
     7441 tcttaagaaa tcggtttcat ttagcttttg agataaaata atagtacagt tttatacgct
     7501 gtttcatatg tttagaaaat ttgaattaga tttgaaaact ctaattttta aatgataaaa
     7561 aaagcgagaa tgctggtttt actgtatatt aaccttagat aactttcatt tttttaaaaa
     7621 aattatgaaa aaaaggtagc tatttaaaag ttgattatgt ataatagaaa cagatgggag
     7681 attattatga tcttctgtta caaaaaagtg attcttatca cgaaaaggag tggtgcacgt
     7741 tgttaacatt atatacttcc ccaagttgta cttcctgcag aaaggctcgt gcgtggttgc
     7801 aagaacatca gattccattt gttgaacgta atattttttc agaaccattg aacagttctg
     7861 aattaaaagc gattttacaa atgacagaag acggaacaga agaaatcatc tcgacacgtt
     7921 ccaaagtatt ccaaaaactg aacatggatt tagatgatct gccgttacaa gaattattgg
     7981 aacttgtgca aaacaatcct ggattgcttc gccgtccaat catgattgat gataaacgtc
     8041 tgcaagttgg ttttaatgaa gatgaaattc gtcggttcct accgcgcgat gtacgacaat
     8101 tagaattacg tcaagcacaa ttgatggctg gattatagaa ggataatacg aaacttggaa
     8161 aag
//
LOCUS       DADGHT010000113         8119 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.115, whole genome shotgun sequence.
ACCESSION   DADGHT010000113 DADGHT010000000
VERSION     DADGHT010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.115"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            166..1803
                     /locus_tag="JX887_002482"
     CDS             166..1803
                     /locus_tag="JX887_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAX1258421.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(1948..2688)
                     /gene="truA"
                     /locus_tag="JX887_002483"
     CDS             complement(1948..2688)
                     /gene="truA"
                     /locus_tag="JX887_002483"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAX1258422.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(2879..3514)
                     /locus_tag="JX887_002484"
     CDS             complement(2879..3514)
                     /locus_tag="JX887_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAX1258423.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3661..4902)
                     /gene="sstT"
                     /locus_tag="JX887_002485"
     CDS             complement(3661..4902)
                     /gene="sstT"
                     /locus_tag="JX887_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAX1258424.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5100..6096
                     /locus_tag="JX887_002486"
                     /pseudo
     CDS             5100..6096
                     /locus_tag="JX887_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6112..>8119
                     /locus_tag="JX887_002487"
     CDS             6112..>8119
                     /locus_tag="JX887_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAX1258425.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
BASE COUNT         2652 a         1509 c         1253 g         2705 t
ORIGIN      
        1 gcttttttac ttattttcat agatttgttg ttctcctttt ttaattctat tttcagtata
       61 ctagaattgt ctttttttaa taagttttgc gttaaatttt tcatagcact agtatgatat
      121 actagaaaag aatcaatttt tattactttt aaataggaga aaaaaatgaa aaaaaacaaa
      181 aaccaaataa tagatatcat ttttatgtta tttctaagtt ttgcttacgt catccctcta
      241 ttcatgtcta tgggaatcta tcatagtgtc aatcaggata cttactttca tttatctcga
      301 atcataggac tagataatgt atggagttct ccagtaaact tcaataactt cgatcatcat
      361 ggaacaatga tgaatatttt ttatccatgg cttactcttt atccagcttt tttattttat
      421 aaaatgatgg gaaatcttgt tttaagttat aatatctact atttttttat cactttttta
      481 acaatggtcg tttcttattt ttctatgaaa caaataaaaa acaatcgtta tatttcgctg
      541 ttattttcga ttatttatac attttccgcc tatcgtgcca ttgacatatt ccatcgtgct
      601 tcattgggag aagctgtcgc tttaacattt ttgcctttga tactaatggg gtgttacgaa
      661 atttatatta gagattacca aaaatggtac tggttgtcta ttggcatgac gctagtagtg
      721 tatactcatt tactttctgt cgctatggtt tctgtattta ttggaggaac gttgtttctt
      781 tctttttatt tttgggacca aaaaatcgct agactcttaa gtcttttaaa agctaccgtc
      841 ctcacctttt ttttaagtgc gggattctta attcctttta ttcaacaatc tagagcacaa
      901 gaattgaaag tcccactggg aaaagaatta agtggtatgg ctcctagtga tatgctgaca
      961 cacattttaa ataataacta taacaactat actattggat tattcttatt tctcggattg
     1021 attggtgctt ttatttttat aaaaaaatta actgctgatg atttatttat tttctttctt
     1081 ggtgtatttg ttcttttttg ttcaaccaat ttatttcctt ggcaactttt taaccataca
     1141 ccagttaaga gtctacaatt tgtctggcgg ttaaatggtt tttcttcttt atttatagcc
     1201 tatacgatga gtatagtgat ctattatatt ttttctacta aaaataattc atggaaaata
     1261 atggtcttta cgtttcttgc actaatattg catctctcag gagtaagcaa ttctatccat
     1321 gctaacaaag attcattaac acttatagca cctgaagacg ctgttgctat agctgaaaat
     1381 tacaatcata ctgattatgc aaacaaagag tcaatctatc atcctgatat gattaataat
     1441 gatcaatatt tactaggtaa ccaggaaata aatccaacaa ctcattttat gagtaacaaa
     1501 cttacaattg aattagataa ttcgaataat aaaaatactg tcttgacgac acctatttat
     1561 cgttataaag ggcaagtggc ttctattaat ggcaaactag tacaaacaaa attatctaag
     1621 tttggcacaa ctgaattaac tattcctcca ggtataaata aagtcgttat tacttatcag
     1681 tacacaaaac tagcaattgc ttcaagatat ttatctatcg ttactttgat tttattttta
     1741 ctttatcgat ttactttttc taaacaaaaa caaccgagaa gagaagtaca acattctcac
     1801 tagattttta tttaagaaag actttttagc tgtacacata aacaggctaa aaagtctttt
     1861 tttatatttc tttaatttgc ttcatacatt atttaacatc gatatttata ctgtgaaaca
     1921 tgcgtttcat ccattatcaa agtattttta tcgataataa acttcatcca aaaacagacc
     1981 ttgtgcaggg acggtttctc ctgcatgttg ccgcactttg ctttcaaata tttcatcgat
     2041 tgtttctatc ggcatggcac ctgtgccgat ttctagtaat gtccccatga taatccgcac
     2101 cattttatat aagaatccgt ctccgacaaa agtaaaatga agcatttctc cctttcgttc
     2161 gatagataat tcatcaatcg tacgcactgt ggattttttt gattttttca atgcagaaaa
     2221 accaatgaaa tcatgtgtac ccactaattt ttcgcaagct gcattcagct tgtccatatc
     2281 caactcttga gggaaataaa agctgtggtt tcgctcaaat gctgaaggaa tcacgttgtt
     2341 ccaaacataa tagctgtatt ttttgcccac cgcattatat cttgaatgga agcgctcagg
     2401 catttcttcg attcttttga tgacaatatc ccgcggaagg taacgattca taaagtcgat
     2461 catttctgcc agtccaattt ctgtgtttgt tttaaaattt gctacttgtc ctcgcgcatg
     2521 ggtgccagca tctgttcttc ctgatccaat aatttctatc tcttcatttg tcatctgatg
     2581 caatactttt tcgatttttc cttgaatggt tttatcgtca tctccaagtc tttgccatcc
     2641 tgaatatctt tttccgtcat attcgattgt caacttgatg tttctcatat tttagtggct
     2701 cctctgtctt ccatttggtc ttctctctac ctttttaaga ttgtagcaca aaatatagct
     2761 cctttcttct ctaaaacaga agctatacaa gaaaactgtg gaaatatata tttcagaaaa
     2821 acaaaaaaca gccaccggat gaagtatccg ctgactgttc aatttgacgg ctcaagtttt
     2881 actgtttgag atgcaagata ctcaaccagg caatgggcac ataattaaag aaaaaactga
     2941 ttctttggca aaaacctatt ttattcagta atggccaaga atttatagaa ggaattcttg
     3001 ccagtccata aatcgccgca aaaagcaaac tgatcacaga cagtccaagg tataagtggc
     3061 ttacgtccat ttgcccattt tttcgataga tcaagaaaag aagaactgga aacaataaaa
     3121 aaccactgta acctaaacct gatccgatat tatggaccca tgtcgagaca ttccacgaag
     3181 attcatgggt attgatactg aacaaacctg taaagataca atcacctata ccatagaacg
     3241 cgatggctgc tgtaactagg gtagctaaca cacgagatgt acttacaaat gcagcataca
     3301 atgcaggcaa tgacaggatg aaaaagatcc ctgaaaccac agaccaaata agaaacgctt
     3361 ttcttacagg actggaaacc tctccaaata cactgatcac gctcttcatt tgatctaatt
     3421 caggataata caatcctaat acgtacggag tcaaaaaatc actcagcacg cctaataata
     3481 aaaagaaaaa accaaattta cgtaaaaaat ccatgatacg cctccaataa caattaccta
     3541 tgcttttaat tgttattata agcgacttta tcttgattta acagaaacct ctatttacac
     3601 gaacatctat ataactcatt aaaaactcga atcattttaa aaatactaaa tatctaacgt
     3661 tcaacgttca cttaatccat ctaaacaatc tttcaatttg attttttccc cacttctttt
     3721 acgcgcgcct agctctccta ttgcagtaaa caacagatca cttgacgaat ttaaggcagt
     3781 ttccattgaa tcctggataa caccgataat aaatccaata ccgacgattt gcatcgcgac
     3841 atcattagag ataccaaaca aactacatgc taatggaatc aataacagtg aaccgcccgc
     3901 aacacctgaa gctccacaag cagctaaagc agacaaaata cataaaagga ctttcaaaac
     3961 aaaaggtgct tcaatcccta aagaatgtac agcagtcaac gtcatcaagg aaatggtaat
     4021 cgcggcaccg cccatattga tcgtagcacc taacgggatc gatatggaat aagactcttt
     4081 tgtcaatttc aatctttcag ccaacatcat gtttatcggg atatttgcgg cagaacttcg
     4141 ggtaaagaaa gcgggaagtg cgctttcttt caaacaaaag aaaatcaatg gatagggatt
     4201 ttctttaata aacaaaaacg tgaggaatgg gtacacaact aatgcgacaa acagcatcgt
     4261 accgatcaaa acaagtaaaa gctgcagata ctctgccaat ccagctattc cagtcgtagc
     4321 aattgattga taaaccaatc ctaaaatccc tatcggagca aatgcaataa tcacttgtac
     4381 gacttgtgac aacgctatag atatctgatc caccaactct tttgtcgatt ctgaacgtgc
     4441 tcgaaaagct agtcccaaca atacagccca gaataagacg ccaaggtaat tcgcatcaat
     4501 aagagattga acaggatttt gtgtgacatt cgtcaacata gtagataaaa cactttccaa
     4561 actttgcggt gctttttcag atactgtttc ttgtaaagta ataggaacag taaaaattga
     4621 acttacaata actgctacaa gtgcagaaag caatgttccc actaaatata agatcaaaat
     4681 aggcttcacg aatgtcttat tcccaatttt atgcttggca attgacgcca tcgtcaagaa
     4741 aaaaaccaga ataggtgcga ttgccttcaa gcaactgaca aacaacgttc ccaatattga
     4801 aataaatgtc catgtgggga aaaagatacc aaacaatatt ccgactaaaa taccaacaac
     4861 aatacgttga actaacgaca tatccaaaaa cttctctaac aaatgaccac cctttcacaa
     4921 ttttaacaat cattgtatca ttttatgcaa agaaactaaa ggtataattt tctaaaaatt
     4981 ctaacaatac aaacaaccat ttcttgctaa ttttgtactt tttctgtcta cacgttgttt
     5041 tttgagatat tctaagttag gatgttatta atgggcaact tatcaggaaa cgttttctta
     5101 tgtttttgtc caattttttt gtgaggtgtt tattcttgaa aaaaataaag aaggagagtt
     5161 atggcttcct gacaatcttt gtcgcttgta taatgatggt tttacagcgt atattgattt
     5221 cagcagtcac tattcctaca tatgcaacaa accctggtcg attctacatc tatacatttt
     5281 tacaaacttc cgttgttatt ggtgcaaatt tgatcccact ttacatgggt taccaatatc
     5341 aaaaaatcgc ccgtttaaaa gttttacatt atttaagtcg ttttgccttt atattcctaa
     5401 tagccacact agtttgcaat atcttttttt tacgtacaag ctggcagctt gaatattcgt
     5461 gattattggc ttatcctaac acctatcagt cagaattact ttacttatgc tgtttcttgt
     5521 actttgcttt tttgtagtat tccttataca gttggatttt taaataaatt atcgaaaaca
     5581 acaattaaat atctactatt atttttaaca attggattag ttggctgctc tactctattt
     5641 aataaagacc cgtttgcatt acagaatgga cagagtattt tatggatttt ttatttattt
     5701 ttaatgggtt atggtttgaa agaatggaac tggaaagaaa aggtccgcta taagcttcct
     5761 caagtattta tcagcttgat tgttttattc ggtttgatta ttttgatgac acaaatttca
     5821 ctcatcatca gaggaaatac agatacagcg ctgaggtttt ctaaaccata ttctctcttc
     5881 gcaatgtatt atactttctc ttcgttttta tttttagaaa tgctatctga taaattaggt
     5941 ataaaaggaa gaggaaattt tcttgctgta tttttgattg tcactcaagt tatatgtaat
     6001 ttccctttag tttcttatcg cgtatctaca tttatgaaac gtgaatttcc aaactcaggg
     6061 aaggcatggc tgataaatat cgggcagttt tttatttgct atttattagc agtgtccctc
     6121 ctagttatct ttttatttta tatacaaaaa atccgtttca ttcatcgttt catcgaatac
     6181 ttcgcttttg attcgattga acaattaact cagcgttgga aaaaaagaat tcattggctt
     6241 tttgttcata aaagttattt tttagttgca gcattttttt actgctttac cttcgtgcag
     6301 attttcgttt tagaaccaaa agaaggttgg aaagaaacta tccaggttgc cttaaaaata
     6361 tttactcagc gacaagcacc catgatcctg acaatcatca ttattatggg atttttcttc
     6421 ttactattgt tgatttccaa tcgtttttgg tacgccttga ctgctacctt gatcattaac
     6481 ttactgctca ctatttcgac agtaatcaaa atggaaatgc gggaagagcc tgtctttcct
     6541 tcagatttaa aaatactgac cggattgtca gaactattat cgatggttag cccagtctta
     6601 ttaatcgtgg gcggattgat ccttctccta ttattgatta ctagtattat tgtacaacgt
     6661 agactacaaa aacagtattc cttgaagatt cattggaaac gtcgatttat cagtatcgct
     6721 gtattattag gatgtttttc gggtgtcttt ttcattaatc acaaaaattc gccttctttc
     6781 ttgctgttta atttatttaa agtaaacaag actttcttta accagcaagg cgccgtaaaa
     6841 gataacggac cagtcattca attcctaaac aatatcgaca ttaaaatcat ggaagaacct
     6901 gctggctatt cgaaagaaaa aattaatgga ataatgaaaa agtacaacac aaaggcagat
     6961 gaaatcaacc aaacaagaag tgactggtta aacaatcaga cgatcgttct caatttaagt
     7021 gaaagcttca gtgatcctgc acgtgtccct aatctgacag tacctacaga ccctattcct
     7081 tacatcaaaa gcattataac agaaggaaca ggaggattga tgttatccgt cggttatggt
     7141 ggcggaacag ctaacatgga atgggaagga ctgacaggct tgagtatcag taacctgtct
     7201 gcttcgttag ttacacctta tacccagcta gtggagcgtc agaaaataag tccaaatatt
     7261 accgatctat tcgatgaaaa aatagccatc catcctttta cagctgctct ttatcgcaga
     7321 aaacaagtgt ttgataaatt tggttttgac aggttctatt atttagacag tccggataaa
     7381 ttaacttata cggataaaat agaacaaagc ccacgcatat cggatgattc agcatacaaa
     7441 gaaaccttga aagctttaca aagcaataca gaaacgtcac aattcatcca attatccact
     7501 atgcaaaacc atatgcctta tgatgattac tatagtgaat tgaactacac tgctgaagga
     7561 actgctgtca ttcctaatag aagaaaagaa ttacaaactt atatgcaagg ccttcactat
     7621 accgatacag cagtaaaaaa attcatccaa gaaatcgaca aaatcgataa accgattacc
     7681 tttgtttttt atggtgacca tttacccgca atctatagtg ggaatgattc gaaaaaatat
     7741 ggattagaac agcaccagac agattatttc atttataaca acaagtatag tcgtgaacaa
     7801 gcagctacgt taaataaaga agttgttgct cctaataact ttggtgctat ggctcttgag
     7861 catgcgaata tcaaagtaac tccttactat gcgttgttga cagaagtatc taatcatcta
     7921 cctgcattaa caattgatcc tacagaaagc ttgtctaatc gttttaatgg aaaacaggtc
     7981 tttgttacag aggatagtca aattatccaa gaaaaaaatt taactgagaa acaaaaagaa
     8041 attctagaag attatcgtct gatacaatat gatcttgttg caggtaacca gtacagtgca
     8101 acatgggcga cacaaaaaa
//
LOCUS       DADGHT010000114         7787 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.116, whole genome shotgun sequence.
ACCESSION   DADGHT010000114 DADGHT010000000
VERSION     DADGHT010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.116"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(105..629)
                     /locus_tag="JX887_002488"
     CDS             complement(105..629)
                     /locus_tag="JX887_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1258426.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="JX887_002489"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="JX887_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAX1258427.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="JX887_002490"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="JX887_002490"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAX1258428.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="JX887_002491"
     CDS             complement(2351..3031)
                     /locus_tag="JX887_002491"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAX1258429.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="JX887_002492"
     CDS             3157..4026
                     /locus_tag="JX887_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1258430.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="JX887_002493"
     CDS             4052..4567
                     /locus_tag="JX887_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258431.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="JX887_002494"
     CDS             complement(4614..5177)
                     /locus_tag="JX887_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1258432.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="JX887_002495"
     CDS             complement(5232..5411)
                     /locus_tag="JX887_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258433.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="JX887_002496"
     CDS             complement(5488..5997)
                     /locus_tag="JX887_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258434.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="JX887_002497"
     CDS             complement(6093..6473)
                     /locus_tag="JX887_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAX1258435.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="JX887_002498"
     CDS             6803..7552
                     /locus_tag="JX887_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAX1258436.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
BASE COUNT         2225 a         1612 c         1382 g         2568 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct atttcctacg
     7741 attagtcaag taaaaggtgc aagaaaaata gctcgtaaac gaaagcg
//
LOCUS       DADGHT010000115         7703 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.117, whole genome shotgun sequence.
ACCESSION   DADGHT010000115 DADGHT010000000
VERSION     DADGHT010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.117"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(495..1841)
                     /gene="gor"
                     /locus_tag="JX887_002499"
     CDS             complement(495..1841)
                     /gene="gor"
                     /locus_tag="JX887_002499"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAX1258437.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(1975..3216)
                     /locus_tag="JX887_002500"
     CDS             complement(1975..3216)
                     /locus_tag="JX887_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAX1258438.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(3234..4157)
                     /locus_tag="JX887_002501"
     CDS             complement(3234..4157)
                     /locus_tag="JX887_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAX1258439.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4378..6870)
                     /locus_tag="JX887_002502"
     CDS             complement(4378..6870)
                     /locus_tag="JX887_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAX1258440.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6877..7344)
                     /locus_tag="JX887_002503"
     CDS             complement(6877..7344)
                     /locus_tag="JX887_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAX1258441.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7480..7553)
                     /locus_tag="JX887_002504"
     tRNA            complement(7480..7553)
                     /locus_tag="JX887_002504"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7517..7519),aa:Arg,seq:acg)
     gene            complement(7611..7684)
                     /locus_tag="JX887_002505"
     tRNA            complement(7611..7684)
                     /locus_tag="JX887_002505"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7648..7650),aa:Pro,seq:tgg)
BASE COUNT         2139 a         1684 c         1237 g         2643 t
ORIGIN      
        1 tttgccgttt tttgagctaa taccgaagga cagctgattg aacactattt gttcggaaaa
       61 agtgactaac tatgacacaa tttttttcac agtccctttt ttcacttgat ttgattcgta
      121 ccagcgaact tgacgagaac tttcttggtt tggtaactat atggtattct tttaacatcc
      181 tcgtttgctt cttctaattt atttatacaa agtcacactt ttttaaacat ctgttcttcg
      241 atacatttct atttctttta aacatcgata ccaatatttt gaacttaaga gtgcatacca
      301 aatggattca tttactcttc gtcagttacg aagataatca aaatctccaa cttccctact
      361 tatttcgttt tgagaattat cgaagcaatc ttacataaat aactaaaaaa caaaaaacca
      421 gaaaatcagt atactgattt tctggtttta catggtttgt tcaataaaaa gctgttggaa
      481 ctgttaatat taaattatcg catcgttacg aattcttccg ctcctgttgg atggatggct
      541 actgtattgt caaagtcttc tttagttgca cccatcttga tagccacggc aaaaccttgc
      601 agcatctcat cgacaccaac accaatagca tgtaagccga cgattctttc ttcttttccg
      661 acacagatca atttcatttc gcatttttgg cgataatcat ttaatgcaaa gtacattggg
      721 gtaaagcgtg aacgataaac tttcaattca ttttcgccat atttttccaa tgcttcttct
      781 tctgtcaaac caattgttgc aattggtgga tgcgtaaaga cgactgtcgg aacaagttta
      841 tagtcaagat aagaatcttt ctttccatta aataaacgtt ctgataaacg tctaccagct
      901 gcgattgcaa caggagtcag atctaattta ccgatcacat caccaacagc aaaaatatgt
      961 tcatccgttg tattttggta tttatctact ttgataaacc cttttttgtc caattccaca
     1021 tttgtatttt ccagacctaa tttttcggta ttcggtacac gtccaccggc aaaaagtaca
     1081 caatcaccag ttaaggtttc accattttca aatagcaccg tatattcgtc attgttttta
     1141 gtaatttctt tagcaatatg atgtgcgtaa gtttttattc cagcttcttg gtacatttgg
     1201 atcaaattgt ccgaaagcat tttatcaaac gttctaagtg gtcgttcttt tcgatatgcc
     1261 cacatgactt cactacctaa accacgaaat acacctgaaa gttcagccgc aatgtatcca
     1321 gcacctaaaa cgattgctct cttaggtaac tctgttaatt caaaaaatcc atttgaatca
     1381 attgcgtatt ctccaccagg aatggtcatt ttacttgcac ggcctccagt agcgatcaag
     1441 attttaggag cacgataggt ttcaccgttt acttcgatcg tttgactatc gataaaagta
     1501 gcgtaacctt ttatagcctc gacatgattg ctatctaatc ctctttgata agcaccgtgt
     1561 agaaaatcaa tatatttttc tcgtctttct actagaccgg cgaaatcaac attttttaaa
     1621 tctgcttgga taccgtaact tgaggcatct cgttcaattg tttccaaaat cgtacttgct
     1681 tgccacataa cttttttagg tacacaaccg acgttgacac atgttccgcc caattcattc
     1741 gcttcaatca gcaaaacttt tgcgccatgc atccctgctc tgtttgctga agcaataccg
     1801 ccagagccgc caccaattac gatgtaatca tatatttgca ttttgttcct ccttattgaa
     1861 gagatcaatc aaaaccttta tttaacgatc ctttttctac agaaaacaag tgtaacactt
     1921 ttcttgaatt ttgtatgcga agatgcttaa aacagggata tatcagcttt ttccttattt
     1981 acgttttcgg atcatatctc caggtttcac cggctgtgcg actggcatag ttaaaatcat
     2041 cattggattt ggtgctcggt caatggattc gccttcttca ttatgcataa cttcaacggt
     2101 ttgactgaaa tgactgaatc ctggaccata aaattcgatt tcatctccta cagaaaacaa
     2161 gtttctctga cgtatcgtag caatctgtgt tgcctcatca taagataata cttcaccgac
     2221 aaatttatat actgggattt tacgacgttc accgaataat tgttcgtttt cagttggtgt
     2281 attgtagtaa aaacctgtag ctaattctcg ttgtgctact ttccataact cgtcgatcca
     2341 ttcttgcttg cagacatagt tttcaggatc ttccatataa ctgtctacag ccgctttata
     2401 gacatttgac accgtagata cataatggat cgatttcatt cttccttcga tcttgaagct
     2461 gtctacgccg ttttcaatca attctggaat atgttcgatc attgacatat ccactgcact
     2521 catcgagaat tcttcttcca cttcgcctgt atcagttaaa ctgtttcgtt cttgaccaaa
     2581 aggcatatcg aacaatccat acttccagcg acaagattga gaacatccgc cacggtttgc
     2641 atcccgcatc gacatatggt tggacaatgt gcatcgacca gaataagaga tacacatggc
     2701 accatggata aatgcttcga tttcggtatc cgtattttta cgaatctctg ccacttcctc
     2761 cattgaaact tcacgagcta aaacgacacg ttccaaccct tcttctttcc agaattccaa
     2821 tgtctcaaaa ttagttgctg aagcttgagt ggataaatgg atcggcagac ctggggcttc
     2881 tgtcgcacaa atttcgatca aagctggatc agaaacaatc actgcagaaa taccgacatc
     2941 acgcaaactg cggaaaaatt cccctgctcc atcttcattt ccttcatggg tgaccatatt
     3001 agcagcaacg tataccttcg catcatgttc ttttgcaaaa gcaactcctt cagccatttc
     3061 ttcataagta aaattacctg cacggcttct taaaccatat gcattcccgc caatatatac
     3121 tgcatctgct ccataatgga tcgcggtttt taacttttcc agtgttcctg ctggcgctag
     3181 gatttctggt cgtttcaatt ttctttttac tgtcatttct ttcatcatac tccttatttg
     3241 atagcagaag gatcaatata aaagaatcct gtatctaatt cacggttttc aggatgcaat
     3301 ttactgattt cgctagtcat tttttccgct ttttcttgat cccagctacc ttctaaaatt
     3361 tgtttttttg cttcggcgaa tagtcgagtg atgtttacga atttttcgcc tggagtaaat
     3421 aatccgtcca atttccatgt acagtaatga tgctgataaa gttcattcaa ttcattcgag
     3481 agattcagat cattgctggc aaaaatatgt gtgccatgac tatcttcata aatagaataa
     3541 tgtgtctctt cttttttagg ttccgagata aaaagacctc tttcacgatc tttttgttcg
     3601 tcttgtttcg tatagttata gtaattctgt agcagtggac gtttggattg atggatgcat
     3661 gtagcaccat acacaagggt ttctacagga atatcgagtt tttcttccat cgccttcatc
     3721 tcttcaaaag gaacttcacg agcaagtact gctccaactg cgcctttttt cgcccagaaa
     3781 ttgatttgac gtgcgctcgt tactaatgtt tcagcatcat aaatatacgg tatacgcaat
     3841 tcaggatttt ttttcatcgt ataaataata cctgtatcac caactgtgat cacatctacg
     3901 tttatttctt ttaaaaaagc caaatattca ggtacatttt tcattttttc aggatgaatg
     3961 atcccattta cagcaatatt cgctttttta ccatacttgt gtgctaattc taccaattgt
     4021 cgctgttctt ctcgtgtaaa tgaagcaggc agacgcaatc caaattgctc ttcaccgaaa
     4081 tatagtgtat ctgcacctgc agcaagcaac tgttctgctt gttcaatagt ttctactgtg
     4141 gttatgagtt cgatcataat tttctcctcc tacaacttca taatagtagc atagctctaa
     4201 aaactttcca atacttcttc tatttaaagt cggatttttg aaaattattt cacaaaaaat
     4261 caaaataaag ttcgatatat tctgtccaaa tataaaaaga gattgtgaca aaaatcttgt
     4321 cacaacctct taatcaagtc ttactattat aaaaattcag ctacacaggc caagtaacta
     4381 tagggaacct actgtttcct ttttaggtcc gcgaacattc aatgtgatct taccttttga
     4441 agcacctact gttacgtggt cacctaaacg aatttctccg ccaagcaaag cctcgctcaa
     4501 tcgatcttca atttcttttt gaagtgcgcg acggattgga cgtgcaccat attcaggatc
     4561 aaatccagct ttcccgatca catcgattgc agatggtgtg attttcactt gaatatcttg
     4621 ttctttcaat cgtttgataa tcgctttgct catgatttgg acgattgtat ggatttcatc
     4681 tttactcaat gaatggaaga cgacagtctc atcgattcga ttcaagaatt caggtcggaa
     4741 agctttcttt aactcttcta agatacgttt ttgcatggct ttgtgatctt tagtaacatc
     4801 ttggacattg aatccgacat ttttttcttc tcgaatttgt gtcgctccga tatttgaagt
     4861 cataatcatg attgtatttc taaagtccac ttttctacct ttagaatctg ttaaatgacc
     4921 atcatccaat acttgcagaa gtaaattgaa aacgtctgga tgtgctttct ccacttcatc
     4981 taagagaatc actgaatatg gtttttgacg aattttttct gtcaactgtc caccttcatc
     5041 ataccctacg tatcctggag gagacccgat taatcggctt gtactgtatt tttccataaa
     5101 ttctgacata tcaacacgga tcagggcatc ttcacttcca aacatgactt ctgaaagtgc
     5161 tttggccaat tctgtttttc cgacaccagt tggtccaagg aacatgaatg aaccaattgg
     5221 acgatcagga tctttcaatc cgcttcgtgc acggcggatc gcacgtgaaa ctgctttgac
     5281 agcctcatct tgaccaacga cacgttcatg cagaagtcct tccagttcta acaagcgttc
     5341 gctttctttt ttctccaact gctgtagagg gacaccagtc cactccgata caactgtagc
     5401 aacatcttct tctgttacac gatcagaata accttgctcc tgttttgctt caattgcaga
     5461 aactttttgc agctttttac gtagtgcttt ttcttgtctg cgtaattgag cagcattttc
     5521 aaagtcttgt ttttggatcg ctgcttcctt ttcttgtact agttcatcga tttctagttt
     5581 gatcacagtt gattttgtta agtgatcggt ttgatccaaa cggactttcg ctgctgattc
     5641 atcgatcaaa tcaattgctt tatcgggtag ttgacgagaa gtgatataac gaacagaaag
     5701 attgactgct gctcgtacag cttcatctgt gatctccact ccatggtgct cttcatatct
     5761 tgtacgtaat ccttgaagaa tcacttctgc ttcttcagga gttggctcat ctacttgaat
     5821 gcgagcaaaa cgtcgctcta atgcagaatc tttttcgata tatttttgat attcatctag
     5881 ggtcgttgct ccgatcgttt gtaattctcc tcgagctaac gccggtttca agatattcga
     5941 agcatcaatt gctccttctg ctccacctgc accaattaag gtatgcaatt catcaatgaa
     6001 taagattact tgaccatcat tatagatttc gtcgatgacc tttttcattc gatcttcaaa
     6061 ttcaccgcga tatttcgtac cagcaaccaa agatcccata tcaagcatca tcaggcgctt
     6121 ttcttgcatg tcttctggca cttcacctaa aatgattttt tgagctaacc cttcagcaat
     6181 ggctgttttg cctacaccag gttcacccac cagtacaggg ttattctttg tccgtcggct
     6241 aagaatctgg ataagccgtt tcacttctct cgaacgacca acaactgggt ccagcttgtt
     6301 ttcttttgct aatttcgtca aatcacgtgc taatgaatct agcgtaggtg ttccttgcgg
     6361 tgtttgccgt ttatcttgta catttacatt tctacgacga ttcattcctt ttccagcaga
     6421 atcaccagct agccccattt tttgtttcag aacttgacgg gcttttgaaa ggctgatacc
     6481 taagttgatc atgattcgag tagccatgat actttcatct tttaataagc tcatcaaaat
     6541 atgttctgtt ccaacttttt gagaaccagt tttcttcact tcgctgctag ctaaagcaaa
     6601 aacttgtttc attcttggtg aatatggaag aaagactcct ttagggtaag aacggatacc
     6661 accataacca atcagatgtt caatttcttc ataaatttcc gtttcattca aatccatttc
     6721 acgtaatact tttccagcaa ttccattttg ctcgaccact aaggctagta aaacatgttc
     6781 tgaactaact gattgatgtt tcaaccgttt tgcttcttct tgtgcaattt ctaatactgc
     6841 ttgggctctt tcagtaaaaa gttcttccat ctaatctcac ttcccatctt cataacttaa
     6901 acgttccaga aatgctcgga gaatccgagc acgtgtatga tcttcatatt cattgaaatt
     6961 caatgtgttt tttgcaattg cactcaacat caagtttcct tctttttttg taattatttg
     7021 gtcttcataa agtttttgaa taatagcaaa agcatttttc tcactgattg tatcatcaaa
     7081 taactgattt atctgctcaa gtaattgttt tttatctgaa atccttactt ttgcaattcg
     7141 tatataacca ccaccaccac gtttgctttc tactagataa ccacgttgga tggtaaaacg
     7201 ggtattaatc acatagttga tttgtgaagg aacacagtta aagaggtctg ccatttcaat
     7261 ccttcgaatc tcgatcattt cactattttc cagaattttc tttatatatg attcaattaa
     7321 atccgaggta ttctgatgtg ccatcttatt cattcccttt gactaatatt gaccttaatt
     7381 ataacgaatt tgataataga aagaaagaag aacgcttttt gttaaataaa tcctttagaa
     7441 tcaacaaaaa aaaatacgga atatactatt ccgtatcgac gcgcccaaga ggagtcgaac
     7501 ccctaacctt ttgatccgta gtcaaacact ctatccagtt gagctatggg cgcatattca
     7561 atttaaaaaa attataaatc atttgaaaac aaaaagcaag ataaaaaaaa tcgggaagac
     7621 aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc tgagctactt
     7681 cccgtttaaa aaataaaaaa gac
//
LOCUS       DADGHT010000116         7467 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.118, whole genome shotgun sequence.
ACCESSION   DADGHT010000116 DADGHT010000000
VERSION     DADGHT010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.118"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            145..516
                     /locus_tag="JX887_002506"
     CDS             145..516
                     /locus_tag="JX887_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258442.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            509..904
                     /locus_tag="JX887_002507"
     CDS             509..904
                     /locus_tag="JX887_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAX1258443.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            906..1283
                     /locus_tag="JX887_002508"
     CDS             906..1283
                     /locus_tag="JX887_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258444.1"
                     /translation="MKDEIIAAISSELKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            1284..1892
                     /locus_tag="JX887_002509"
     CDS             1284..1892
                     /locus_tag="JX887_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1258445.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            1892..2233
                     /locus_tag="JX887_002510"
     CDS             1892..2233
                     /locus_tag="JX887_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258446.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            2475..5264
                     /locus_tag="JX887_002511"
     CDS             2475..5264
                     /locus_tag="JX887_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAX1258447.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            5254..5994
                     /locus_tag="JX887_002512"
     CDS             5254..5994
                     /locus_tag="JX887_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1258448.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            5991..>7467
                     /locus_tag="JX887_002513"
     CDS             5991..>7467
                     /locus_tag="JX887_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258449.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELT"
BASE COUNT         2717 a          936 c         1478 g         2336 t
ORIGIN      
        1 atcagaaaaa acagtatctt cagttagacg tggcgataca acgattagtt atgcttcaac
       61 aacaaatgat gttagtgagt tacttctagg ctatggtgat ttgatacgaa gagttattgg
      121 ttgtggagga ttggagtttt tttaatgaat gaagcagata ttttagaaac tacttatgaa
      181 gatagttgta ttattgaaag actgacggac attgaagatt ctaatacaaa tattactatt
      241 caagattaca aaaaagtata tgataatcct atttcttgcg ctctttcaca aggtcaaatc
      301 gatggactag cagtcataga agatggagag atggtaaatg tttcaactga cacatataaa
      361 ttatttgttc atcctaagat taaactaaaa aaaggagatc gaataacaat aactcaaaag
      421 gccagtggct taattttttc tctatttgct actaagcctt tttactatcc tagtcattgt
      481 gaagtgaatt tgataggaag tgagaaaaat gggtaatctc aaatatgaat caaatgcaga
      541 aaagatcatt gagaatttta aaaatatgac tgtaattgct caaaaagaag gaatatcctt
      601 cgttaacgat tcaatgaata aagtcgttag tttagctaaa ccattaactc ctgtaaaatc
      661 aggtaattta aggcgaggat atcgtgtagt aaaagctaga aaactatcaa gcggtcgaat
      721 tgttggagaa gttataaaca atgaacatta ttttaaatat gtagaagaag gtcataggac
      781 taaaaatggt ggctttgtca aagggaaatt catgttaact cgtgcaacga atcttgcaaa
      841 tatgtcttat attcctcgaa gatttaaaca aatggcaata aaaatcgtta agaaaggaaa
      901 gtaacatgaa agatgaaatc attgctgcaa tcagtagcga attaaaagaa atctatcctg
      961 atgggacaat atatcttgat tcagttatgc agtcaactaa agatttttat ttcgttttat
     1021 cagtaatgga atctggaact gaaaatgtag gaattgatat tcaaaatgtt tctttcttaa
     1081 ttgatattgc attgattgat aataacccta atagaaattt aattaatgaa ttagtctcac
     1141 gttgtgggac tttttttaat acgattacaa tcgatgagca aatattattt ccaaaagcct
     1201 atttacctga tgaagcagat ggtgttcaac atattcgttt tacattagaa tttccacaat
     1261 atattgaatg gagtgaaaga taaatgggag aaaaaagaag taaaaccgga attatttctg
     1321 tcgaaaaacc tacttggttt cctttggaag atgagacagg gaattttccg gtatatggta
     1381 ctgcgttgcc aatgggaaca gcagtaagta tcaaaccaac agctaattat gaaacaacac
     1441 aagattatgg ggattcagtg gttcaagatc aatttacagc ttttggtggt gcagaagttg
     1501 aactggaagc aaatggatat actcataaag ttttatctac aattactgga gggaaaattg
     1561 ttaaaggtgg tgccttgcgt tctggagaag atattgcgca agatggtgcg tttgcatata
     1621 gacgtaaaaa atcgaatggg aaataccgtt atacggtctt ttataaagga cagtttgctc
     1681 tagattcaga tgaaacatca acgattgaag gaagtaaagt aagttttact catccaactt
     1741 ggaagggttc atttgtagat gtaccaggac ttggatatat gtattcagtt gatgaagatg
     1801 atgaaggcgt ggataaagca atgatcggaa attggtttac aaaagtagca attccaattg
     1861 aagaagcaga actttcagga ggtacagaat aatgtcaaaa tatcaaacaa cgattaaatt
     1921 aacgaaaaaa gacgaagaag gtaaatatga gcaagtacaa tttaaatctg ctgaattttt
     1981 accaggaaca gttgtagaag atgctgcagg agttatggaa gaaatgcaaa cagcgactga
     2041 taagcaatca gttaaaaaag ctttaagtcg tgcttattca tttattgcag atactttatt
     2101 tgagggacaa tttactggtg aagattattg caaaggaatt gatgctcgtg agattgcctc
     2161 attgacagga aaattattga agtctgttac tgcaggtttt gatgaaactt atacagagac
     2221 gaaaaaaaag taagtgaggc gctcaagtca ccttcattta agtattcgat tacttaccga
     2281 gaattagata taaagacgca attactcgaa gcaggttgga cgttaccaga aattgaacgt
     2341 actgacttgg atgagttaat gcgtcttttt gcttttagag atgcggtaaa agagcatgaa
     2401 gatgttgagt actatgataa tttcactcaa ttttaggagg tgatactttg aataacgatg
     2461 acctaattct gaagatgata ctagatgaat ctggttttac tgccggtatg aataatgctg
     2521 tcaaaaagtt gaactctttt gatgaaacaa tcgaaagaaa aagtagaaat agtggcagtt
     2581 cattaggtag tatttggaaa atatttgctg gaagttttct agctagcgga gtaactagaa
     2641 tcgtaggagc tggctttgat ctaatcaagg gttccataag tggagcggtt gatcgagtag
     2701 atacgatgaa taacgctcta cgaaatttcc aaaatatggg atttagtaat tcagaaatta
     2761 tgaagaatat cggaaagaat gggcttttat ctcaaggtat tcaaggactt cctactgctt
     2821 tgaatgatgc gataagtcat gttcaacttc ttgcttcttc tacaggtgat ttaactcgtt
     2881 caactcaaat atttaaagct ttaaatgatg gaattcttgg tttcggtggt tcaactgatc
     2941 aagttaatga agctgttatt caattatctc aaagtttctc aaacggaaaa gtagacgcac
     3001 aaacttggaa ctcaatgatc aacgctcaac ttggacctac tctttctgct attgctaaaa
     3061 agatgggaat tacaatggga gatctgaaag aaggtttatc tcaaggtaag atttctgttg
     3121 aagaattcca aaatcaatta atagaaatgg ataccaaagg tggcggagga cttaaatcat
     3181 taagtcaaat cgctaaagat tctactaagg gaattaaaac ctctatacaa aatgcaaaaa
     3241 cagctgttac acgtggtgtt ggtgaggtaa tagaaggatt aaataaagca ttagtagatt
     3301 cagatttagg tggatttaag ggaattattg ataaagtggg cagttcaatg gaatcgttct
     3361 taaaagtaat tgctgcaaat attcctacag cagtatcatt tttaagtaat ttatttaacg
     3421 aaattcaaaa atttggttct gctttgaaat tcatgatgcc ctttcttgtt cctgcagcta
     3481 ccgcttttgg agcgttcatg tttcaactta aaggtatacc agcaataata aaaagcttca
     3541 ataattttaa gaatgccata attggcgttg gaaattcatt aaagattatg ggggcaatag
     3601 ctgctgctaa tccatttgtt ttaattattg gtgcagtcgt tggtgcaata gctgttttcg
     3661 gttactttat ggcaaccaat gaagagctta gaaacaaggt tatatctatt tggaatgatg
     3721 tgaaagattc cgtaattggt gtattaaaaa atataaagga ctggggaatt gatacttgga
     3781 attctgctaa agaaatggca tcaaatgcag ttgagggtgt caaagatgct tggtcaggaa
     3841 caaaggaatg gttttctaac acctggaaag gtattaagga tggggccaca ggtttatttg
     3901 ataaaacagt agagacttca agaaatgcag tcgatagtgt aaaaaatgca tggtctaata
     3961 tgaagaaatg gttttctgat acttggcaaa gtataaaaga ttcagccaga gaaaaatgga
     4021 atggaatcaa aggttctatt atgtcagttg ctggtccatt gattacaggt ataaagaatg
     4081 catttttaca tgttactttt tatctagaga ccttatggaa taatttagtt gagattggta
     4141 aaaacgtctt tgagatttta aaaaatgtta tacttgcgcc ggttttgttt attacctcca
     4201 tgatttctgg tggatgggaa gaaacaaaaa ataatatgat tgctgtttgg aataatatta
     4261 aagaaagtgc cataaatatt tgggaatcta taaagaatat atttgtaagt tattttacaa
     4321 atatttattt tgctgcactc aatatttgga cagggttcaa gcttacattg ataaatattt
     4381 ggaatgaagt ggtaaatcaa gctaaatcga tttggttaaa cataaagtat ttttttatta
     4441 atctttggat tgatataaaa tattttgcaa ttcagaaatg gattgaattg aagttttcta
     4501 ttattcaaac ttggatcgat ttaaaatata atgccattac tacttggaat aatattaaac
     4561 agtttttcaa agatacttgg aaaaatatta aagatacggc atacaatacg tggatttcta
     4621 taaaaaatac catgattaat acatggaata acattaagga ctctttctgg aatattgtta
     4681 ctggaattgt taattctgct gaaaatgcat ggacaaatct aaaaaatggt gtttcaaatg
     4741 ctattaatcg ggtaaaagaa atctttaatt cgttaaggga agtcaattta tttgaaattg
     4801 gcaagaacat cattgatgga cttataaatg gtgtaaaaga aaagtggaat gctttgaaag
     4861 atactatcaa aggtattgca ggtaatatca aaaattggat taaaggagct ttagatattc
     4921 attctccatc aagatggatg cgtgatatgg ttggtaaaaa tattgttcaa ggtattatcg
     4981 ttggtattga taaagagcaa agtaagttag atcaaaccat gacaaattta gtaaaaacac
     5041 cgtctgttca acctgtagta aatggaataa gtcacctacc aattacacaa acaaagcaaa
     5101 atatatctgc tagtgaaaca aaagaaattc atttacattt aaatgtttat ggagatttac
     5161 ctgattcaat ggttcggaag attaccacaa aaattaaaac agaattgaca agacaaatga
     5221 aacgagatgc tggtgcagta ggaggaacat tatatgcaac ttaagagagg acaatttttt
     5281 attaatcaac attattcttc tgaatttaat gtgtatattc aaaacaggcc tgcttctgtt
     5341 tcagctagtc gagtaattga attgagagag cgagaaggaa atgattctat cattattgat
     5401 aaaggctatt acaaaaatgt gactagaaag attgagtgtt actataaagc accttcaatt
     5461 gatatggtgc aggagtggga agatcgaatc actgaatggt tagatatgtc gtcttatagt
     5521 gattttattc tttactatga tgaacaatat atttatcaag ctgtagtaat agaaggacct
     5581 gaatttaaag gaacaagaaa aacaggaaat attgtccctt ttgaatttac agtgagtatt
     5641 cgaccattta aggaaaatta caatggtaga tttactattc gacaaacaga aacttttgaa
     5701 atttataacc cagagaagta ttcttcaaaa ccgcttatta aattgagtgg ttctggagat
     5761 gcttcttttt atattaataa ggataaatat gatttgaaat cgttggacag agaattattt
     5821 atagattcta aattagaaga ggcttatcga aaattagatg gtaatttaga acatcaggat
     5881 caggtcacct tatttttaga ttttccattt ttatatcctg gaaaaaatga aattaaatgg
     5941 acgaaaaata ttcattcatt tgaaataatg cctaggtggt ggagaaaagt atgaaaccaa
     6001 gaatatatag tcctactgaa acagatttct caacgaatgg cttaggaatt ttaaaggatt
     6061 gtacaagatg tggaatatat gaagtagcta atggaaaata tgaattagag ttggattatc
     6121 ctttaggaac tagatttgat gaatattttg aaaatgacta tcaaataaaa gcaaagccaa
     6181 acgatcaaga agagtatcat atctttttta ttgatgataa agatatagat acttttttaa
     6241 atacagtaac tatttatgct cagagtcgta caaatcgact tggaagacgg gtagtcactc
     6301 ttgtggaagt ggactctaaa actggtcaag aagcgatatc aattattgaa actaaaatgg
     6361 ataaaaaatc tgacatacga ctttattctg atattacggc tgtttctagc acaatctttg
     6421 aagcgagaaa tgttttaaat tgtattgctg gtgaacaagg atcattgctt caatattggg
     6481 gcggagaaat taaacgtgaa ccatttaagc tttctttgtt aaagcgaaga ggtcgcaata
     6541 atgttggaac gattcggtat ggaaaagata tgtctggttt gaaggtcaaa ttagattgga
     6601 caggtataaa aacaagaatt attccatatg ctgatcctca aagtgaagta ggtacgacta
     6661 atcgaattta tggttcgcca gtagatagtg cctatattaa taactatcct gatgtctata
     6721 cagaacatgt tcagtttaca gaagaacaag gagtaaaaga cattaagagc ttaaataaaa
     6781 tagctaaaaa ttactttaaa acgatcaatc ctggctgtga taagcctaaa gtttctatta
     6841 cggttgaatt tgataagttg actgatagtg aagaagcgaa agaatttgcg aagattagaa
     6901 attatggtct gtttgataca tttaaaatat atcataaaaa atataatatt tatcttgaat
     6961 caaaggttag tggactacaa tacgattctt tatctgaaaa aactttgaaa ttagaagcag
     7021 gagacattca agttgctttt tatcagcaac aagctgtaac tattcaggat aaattaaaag
     7081 attatgcaac gaataattat atgagtgatt ttaatgatta tgtttcttca atgattacag
     7141 gtcaaggcag tgcaggagga tatgtagttt tatggccaaa agaaaaacct tccaacatct
     7201 ttattatgga taatccagat ttagaaaagg caagagaagt actaagaatg aataaaaatg
     7261 ggattgcttt ttctaagaaa ggatggcggg ggccttttaa ttcagcttgg acattagata
     7321 gtatatttaa tgccaatttt atacaaactg gattaatcaa agcagatatc tttcaaaatt
     7381 cttttaacaa gactggagat gtattgaaat tagttaatgg actactccaa atttggaaca
     7441 acaaaaagaa aataatggag ttaacta
//
LOCUS       DADGHT010000117         7408 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.119, whole genome shotgun sequence.
ACCESSION   DADGHT010000117 DADGHT010000000
VERSION     DADGHT010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.119"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(13..348)
                     /locus_tag="JX887_002514"
     CDS             complement(13..348)
                     /locus_tag="JX887_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAX1258450.1"
                     /translation="MKMNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSK
                     YHTKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQ
                     RLEERMEEL"
     gene            complement(332..604)
                     /locus_tag="JX887_002515"
     CDS             complement(332..604)
                     /locus_tag="JX887_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAX1258451.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(1055..1858)
                     /locus_tag="JX887_002516"
     CDS             complement(1055..1858)
                     /locus_tag="JX887_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAX1258452.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(1836..2960)
                     /locus_tag="JX887_002517"
     CDS             complement(1836..2960)
                     /locus_tag="JX887_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1258453.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(2976..3791)
                     /locus_tag="JX887_002518"
     CDS             complement(2976..3791)
                     /locus_tag="JX887_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAX1258454.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(3781..4662)
                     /locus_tag="JX887_002519"
     CDS             complement(3781..4662)
                     /locus_tag="JX887_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAX1258455.1"
                     /translation="MSEMKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAP
                     TKEFVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNL
                     YKPLFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAG
                     ITAWKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVM
                     TIVQGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAV
                     FLGVIFKFVEKGVYYEN"
     gene            complement(4738..6027)
                     /locus_tag="JX887_002520"
     CDS             complement(4738..6027)
                     /locus_tag="JX887_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002581297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAX1258456.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(6255..6899)
                     /locus_tag="JX887_002521"
                     /pseudo
     CDS             complement(6255..6899)
                     /locus_tag="JX887_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2278 a         1589 c         1136 g         2405 t
ORIGIN      
        1 tttttagtat tattataatt cttccatgcg ttcttccagt cgctgtaaat cgcttggact
       61 taattcccca atttttttcc atttgacctt tttgttgttt ttgggtaatt cgtttagagt
      121 tcctacgtca atccaagatt ctttttttag tcctgcctgt ttccaatccc ttatttcaac
      181 gtatttcagc tttattttat cggatttagt atgatatttt gaagtaattg acagaaacga
      241 aattgtgtcc agtccatttt ttagaatata gacaggccgg cgtttaccgc cctctgcagc
      301 tgtgaaagca acgtagacgg ttgctatatc attagtattc atcttcattg aaccattctt
      361 caattttttc gtcagtgtct agtttttgga caggcaattt ttccgctaat ctttgaatat
      421 tatggattcg tttacttttt tccgacaatt caatagaaaa tgggattttt ccttgctcaa
      481 caatttgctt ataaaaaacg gtgacggctg ttttggggct catgcctagt tcatcaataa
      541 tgctttctgc ttcatttttc aatttttcgt ccatagaaat ttgtaactta gccattttct
      601 ccacctcttt ctgacaaaca cattatatca cggaaagagt tcaaatggaa ttaatacaac
      661 tacttttgaa ctccttgaaa tgcagtgtat ttatctaaat ataaggaaag gatatagtgc
      721 taaatggcct tgatagatag aaaagtttca aaatccgcca cagcgataat tgaagcgaac
      781 actcaacgac acacagaaca ggaaaagact cctaaaagaa ccaaattaac taggacgtgt
      841 ctgaaaactc cacaaagatg tggtatgctc tggtaaaaaa cgaatggcac aaccacgaag
      901 accgatatgg ttcttggaaa actttctcca ccctttttgt aattggaggg atagtggttt
      961 attgatagcg attttccaag ttcttcaagt ggaaccagac attgagcacc acggctaaaa
     1021 agtgaatgaa gtctttattt ttaatcaata atttttaatg attaccagta attggttttt
     1081 tcatgcgccc tatttctatt tgatgtggag ttaaataatg ctgataagta aaaatttttc
     1141 cgtcaattaa actgccacta gtgaatcctg ttctattggt aaaaagagaa tagtctgggt
     1201 attcatctac accaaatgat aaagattcag ccataaactg ttttttacca gcaaattcag
     1261 cactgctacc ttgatggata tgtcctacaa aaatacctaa aatatcactt tcggcaatca
     1321 attcagcaaa accttccgga acttcagtta caatagatgg atcttcccac gacaatggat
     1381 gatgaaccaa taaaatcgtt cccttttcag caggtgtacc caaccactct tgtaattgaa
     1441 tcatctgtcc tatcgatatt tttccttcgt gctgggtatc ttgagcagaa tccaaggaaa
     1501 taattcgtaa cccattttga ttcgtacaat ggatatactc tcccgtttca ttgctttcaa
     1561 cactcattcc ttcaaagaaa acactgcgac gatcatgatt cccacgacaa aaatagtaag
     1621 gtgtggttgg gaaatattga tccaacattt tccgtaagac ttgataatca gaaatccccc
     1681 cttcatgtac taaatcacct gttaatagaa taaaatcgta cactgttaac gagagttctt
     1741 gtaacaattt ttccaatgcc aactgtggat ttttaattgt tggaaatagt tcagcagtaa
     1801 acaagttagt ttgatagttt tctctaaaat ggatatcaga gagatgcaaa aagcgcatgg
     1861 ctattccctc tttcttcaat aaaataatca ggatatccta aattttcttg cgtctgataa
     1921 tcaaaaaaat gcattctttc aggttctatg cggagattga ctgcatcacc aatctgccaa
     1981 gtaggttttt cattaaggac aatcatttct ataccatcga ctttaacggt gtacgcataa
     2041 ctttgaccta atagctcacg atacttcact tgaccgtgta aatcgcttgt ttcttttgaa
     2101 aaggttacgt gttctggtct tatgcctaaa tacaatgagc cactaacctg aagaagttgt
     2161 ttttgccaag ctggattcaa tgttaaaaat tgactggcta cctttaatgt tccttgatca
     2221 taagtaactg gcataatatt catgcctggc gaaccaataa aatttgcagt aaaagtattt
     2281 ttaggtttcg tataaacatt tttcggcgta tcaatcatct gaattctacc ttcattcaat
     2341 aaaacaatcc ggtcagctaa cgtcatcgct tcaatttgat catgagtgac gtagacaaaa
     2401 gtttgtttat aacgttgatg aatttttacc aattcttttc gtgcatccaa tcgtaaacgc
     2461 acatccaaat ttgataacgg ttcatctaat aaaaaataat tactccgttt aaccaccgca
     2521 cgagccaatg ctacacgctg ccgttgccct cctgacaaat ctttaggaag tcgatcttgg
     2581 tatggcgtta aacctaacat cttcaaagct tcttccaaac ggtgctgaat gtcagctgtc
     2641 ttaattttat tcgcccttaa tgcaaaaata atattctcct ttacagtcat gtgaggatat
     2701 aaagcataat tttgaaaaac cattgcgatc tctcgttctc cacaaggtag cttatttgct
     2761 agttgtgtac ctaaaaaaag ctctccactc gtaatttttt ccaaaccagc aatcattctc
     2821 agcaaagtag attttcctga accagatggt cccagtaaca caattcgttc tccagcggcc
     2881 acagctaaat caatttcttt taaaatggta tgttctccat atttttttcc gatatttctt
     2941 aattcaagcg tttctcccat gatttgtcct ccaatttatt taatacctgc agaaacaaaa
     3001 gtcccgataa tatatttttg aaaaattgca tacaagacta acggtacaaa cattgtaatt
     3061 aaactaatcg ccattgctac ggtaaaattt gtcccacctt cagaactaat ataggtctgc
     3121 atcgccaacg gcaaagtata attatctact gtccgtaaaa ttaataccgg ccaaacatac
     3181 tcattccaag aggtaataaa aaaccaaata ccggtagaag taatcgcatg tctagtaaga
     3241 ggaaaaacaa ttttactcat gacggttgtt tgtttgatgt tatccaatgc cgccacatct
     3301 agaaggctca ctggaatttc ccgcattgtt tgcgtcaata aaaaaatgcc catcgcatca
     3361 gcaaattgtg gtattatcac accccaagta gtatcaatta aattaagttt tgcaatcaac
     3421 aaataattag gaatcatcgc aacagtaaaa ggaatgaaca tcgtaccaat gatgataaag
     3481 taccagattt tcttcccttt gattcggcaa taagtaaaac tatatgccgc aaaaaaagct
     3541 acgcctaact taacaaccgt tataattgta gcaataaaaa aagtatttct cgtaattttg
     3601 ataattggaa gattttcgaa caaatagcaa aaattttcca aggtaaacgg ctgtggtatc
     3661 aaactagtaa tcgtctgata ggcatctttc aatggcttaa aagaattggc cataataaac
     3721 aataatggat agataataat gattatgatg aacataaata agagatgtgg caaccagcgt
     3781 ttaattttca tagtaaaccc ccttttccac aaatttaaat attaccccta agaaaacagc
     3841 aaatattaat aaagttaaaa ctgaaattgc tgaagattct ccgactttat acatttcaaa
     3901 agccttttga taagcataat agatcacgtt tgcactacca ttattcggtc caccacgagt
     3961 gatgatctta atcggagtaa acacatactg cagaccttga acaatggtca tcaccaataa
     4021 atatagtcct gtcgaactac tcataggcaa cacaattgta aaaaaaatgc gccagatggg
     4081 tacacgatcc aacttagctg cttcgatcat ctcttgatca attcccacaa ttgctgcaaa
     4141 aatgacaatg aaattataac caaaaacttt ccaagcagta atacctgcaa tcacagcaat
     4201 tacccaacct tgtaaattca tccacatagg cagtcttaaa ccaaaatttc ccaacaagac
     4261 agcaattggt cccgataccg gatttaatat ccatgtaaaa accatccccg ccactaccaa
     4321 agaaatcaca gctggaataa aaaataatgg tttatacaaa ttctgccctt tttctataac
     4381 tattcctaat aaaaaggatg taatatatgg gaacacacag ctcagcaaga caaatagaac
     4441 ggtataggac aaagtattct tcaacacttt atgaaagact ggatcagtca gcacctttac
     4501 atagttggca aagccaacaa attctttagt gggggccacc atattccagt caaaaaaact
     4561 caaatagatc gtataaatca atggataaaa aacaaacacg cccaacaaaa taattgctgg
     4621 cgccagatac aaataaccta catagcgctt catttccgac agcctcctca tccttatgtc
     4681 aaaagcagac gaccttgttt ttcctttctt acaggcgctg tcgtctgctt gctttgctta
     4741 tttgagtaac tcattaattt ccttttgagt agctttcatc gtttcattga cggaattacc
     4801 tgataaaatt ttatcccgca tatccaacaa tttttgttca gcttctaatc cagcatctcc
     4861 aggaaatgaa ctccaactga ccatcttatc catctgatca attgctggta tcatcatctg
     4921 attttcagct aagaaagctt ttaatccatt ttgggcgtct gcaacatctt tacgtggtgg
     4981 taaataacca gtaccttctg tccatttagc taaagattca acactataaa gatattttaa
     5041 gaaatcccaa gttgcttcct ttttcttatc cgtttgtgat gtaacagcta acattgcgcc
     5101 accagcaggt agtttaactt ttttcccttc ccaacttggt gactcaactg ctttagcagt
     5161 aaaagtacta tttttttgaa tgttgtccct ttgagcaata gtggtataga ccatcgcgac
     5221 gttaccatca ataaagcttt gcacaccttg ttcccacgta gtgtgtaatg ccgtctggtc
     5281 ttttaccatc ctttgatata attcataagc agcgatacca tctttagaag caaaggtagc
     5341 tttgccatct tttattacac ttgccccatt actttctaaa attgcttgtt gtgcccaatt
     5401 atcagcaggt tcttgaatat acacgccata ctttccagtt ttttctttta ttatcttaga
     5461 aaaagtttga acttcttccc aagtttttgg accattttca tccaagcccg ctgcttttaa
     5521 tatatcttga tttaaatata aaaccggatt actaatggag taaggaatac ccacttgttt
     5581 accatctttt tcagacagtg ccatgatatt gtctaaaaaa tgatctttaa aataatcagc
     5641 attatccgga tccacttctt ctactaaaga ttgaggatta gtatatttga aattttctgc
     5701 aaaataatct ttaaaagccc atcccacttg tactacgtcc ggtatttctt tggaggcaac
     5761 agaagcttgt aaattttgca tcaagccttt atacatatca ggattatatt ttgctacaac
     5821 cttcactttg tcttgagatt gattgtattt atctactaat tcattcactg tttttccacc
     5881 tagggtatcc gcattaacat gccaatactc tatcgttaca cgaccctccg atttttttgt
     5941 tgtcttggta ttcccactac cacaagctgc caaagagatg acacttaaaa cagacacaac
     6001 ccctataaca agatttttct ttaacataac attaacttcc tcctaatttc tttatggcca
     6061 tttttctaat caagaaatat tatgaactac caatgtaaat ttctagttaa ttttctgtaa
     6121 ataattcgaa atttgtgcat ttcggggtac agggtcactg gacatatcca tcaagctaag
     6181 aataaagccc ccatatggtc atgtatccca tctccaaatc tcttaactcc tctgttttga
     6241 ttataaaata gtttattctg tgctcctttc ttccataaat aggcccatgc acaacgtgag
     6301 gttatattat aaacaccaca gcgcgcaagg tactcaatcg tttctagttc attgactgtc
     6361 catacagaaa atgtcaatcc tagctgctgc cccacttcac gggccaactt agttaaccat
     6421 ccttcatgaa tattgacgat ttgaacgctt tgataggcta atttctgtaa ggtatcgatc
     6481 aaatctgctt cggtaatatc cccaagtttt ttcccttcga actgattttc aatattataa
     6541 aatatatgct ttccccaaat cgcagcccaa gataattgta catagccact aagaacaatt
     6601 tgtggccaga tttgataggt ttgtgccagc gaaaaaacgg ccatttccaa tccctcttct
     6661 tttaaatcac agttaatggt catggttgcc ttctcattgg ccactgcttg aaacacctgc
     6721 tcaagggtta ccgaatctgg gacaacttct tacctgtcat gggctagtat tagcgtacca
     6781 tctgtttgct gacgcacatc tacttcaaaa caaagctggc gatccaaaca aaagcgaaga
     6841 aatgcccagc tattctcctc cgtattgtca ctaccagagt gtgcagtgat catggtcatt
     6901 ttgacccctc ctttaattcc gtgattttct cccacacgtc cactataccg atgaagcgtt
     6961 aatttcttgt taatttcttg taaattccct gcgttttttc agtaaactag ttgtaaatct
     7021 tgcatgctcc ttcctacgaa ctcatgaatc gtcgattttg cccttctagc tagtttcacc
     7081 aattaagtag ttctacattc cccgctttta acctactaca cctttttttg ttttcagcta
     7141 ttccttcttc ttgctgaaag tccttgaggt tctttcttac aggataccat caaggtgttc
     7201 aatggcttat tcccattgaa tgaccgagac ttactatcag atttctgctc gttgaaccaa
     7261 gtctttgata caggatttct tccgtcatct tctcacaaat accaccttgc gtttctctag
     7321 cgattggtcg atgtgcaccc tcccagtgga ctgtcactac ccctttttgc tatgcctagc
     7381 ccacaaaaaa agctgtcctc acagacag
//
LOCUS       DADGHT010000118         6812 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.120, whole genome shotgun sequence.
ACCESSION   DADGHT010000118 DADGHT010000000
VERSION     DADGHT010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.120"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(24..722)
                     /locus_tag="JX887_002522"
     CDS             complement(24..722)
                     /locus_tag="JX887_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAX1258457.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(715..2067)
                     /locus_tag="JX887_002523"
     CDS             complement(715..2067)
                     /locus_tag="JX887_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAX1258458.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2290..3690)
                     /locus_tag="JX887_002524"
     CDS             complement(2290..3690)
                     /locus_tag="JX887_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAX1258459.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3851..4588
                     /locus_tag="JX887_002525"
     CDS             3851..4588
                     /locus_tag="JX887_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAX1258460.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4713..5192
                     /locus_tag="JX887_002526"
     CDS             4713..5192
                     /locus_tag="JX887_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAX1258461.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5189..5956
                     /locus_tag="JX887_002527"
     CDS             5189..5956
                     /locus_tag="JX887_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258462.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6186..6755
                     /gene="lepB"
                     /locus_tag="JX887_002528"
     CDS             6186..6755
                     /gene="lepB"
                     /locus_tag="JX887_002528"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAX1258463.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
BASE COUNT         2320 a         1287 c         1264 g         1941 t
ORIGIN      
        1 tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat
       61 tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt
      121 cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca
      181 gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct
      241 tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct
      301 tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga
      361 tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc
      421 aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa
      481 gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg
      541 ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc
      601 gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta
      661 tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc
      721 acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac
      781 agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat
      841 tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag
      901 acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc
      961 ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt
     1021 ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac
     1081 ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt
     1141 gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc
     1201 aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata
     1261 cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt
     1321 gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt
     1381 tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg
     1441 acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc
     1501 atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga
     1561 atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt
     1621 ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa
     1681 gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag
     1741 gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc
     1801 ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat
     1861 attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg
     1921 gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg
     1981 taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc
     2041 aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat
     2101 aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa
     2161 gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa
     2221 cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat
     2281 attcccattt taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt
     2341 ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag
     2401 tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc
     2461 agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt
     2521 agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac
     2581 tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact
     2641 tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc
     2701 gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt
     2761 gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata
     2821 aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc
     2881 caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa
     2941 tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca
     3001 ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat
     3061 caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa
     3121 cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca
     3181 acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg
     3241 aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg
     3301 ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa
     3361 aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc
     3421 cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt
     3481 cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg
     3541 ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca atatataata
     3601 aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg
     3661 cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct
     3721 accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag
     3781 ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag
     3841 gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa
     3901 ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa
     3961 gatattaata catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca
     4021 atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt
     4081 gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca
     4141 tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa
     4201 ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt
     4261 agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac
     4321 catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat
     4381 ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt
     4441 gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc
     4501 caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac
     4561 atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat
     4621 aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa
     4681 caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc
     4741 caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt
     4801 ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt
     4861 cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta
     4921 catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa
     4981 gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa
     5041 gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca
     5101 cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa
     5161 cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt
     5221 gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat
     5281 tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca
     5341 aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt
     5401 tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt
     5461 tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg
     5521 aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca
     5581 attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga
     5641 actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt
     5701 caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga
     5761 aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt
     5821 catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa
     5881 attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag
     5941 aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta
     6001 ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa
     6061 gataagacga acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa
     6121 agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt
     6181 aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt
     6241 tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta
     6301 cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata
     6361 ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta
     6421 tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg
     6481 atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat
     6541 atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact
     6601 ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa
     6661 aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc
     6721 gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac
     6781 atgttttttg tcacagcttc tttttccgaa aa
//
LOCUS       DADGHT010000119         6644 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.121, whole genome shotgun sequence.
ACCESSION   DADGHT010000119 DADGHT010000000
VERSION     DADGHT010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.121"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1..859)
                     /locus_tag="JX887_002529"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="JX887_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="JX887_002530"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="JX887_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAX1258464.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="JX887_002531"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="JX887_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="JX887_002532"
     CDS             complement(2143..2373)
                     /locus_tag="JX887_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HAX1258465.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="JX887_002533"
     CDS             complement(2603..3421)
                     /locus_tag="JX887_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAX1258466.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="JX887_002534"
     CDS             3582..4271
                     /locus_tag="JX887_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAX1258467.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="JX887_002535"
     CDS             4285..5787
                     /locus_tag="JX887_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAX1258468.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="JX887_002536"
     CDS             5800..6276
                     /locus_tag="JX887_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAX1258469.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="JX887_002537"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="JX887_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2174 a         1032 c         1203 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttattatcca aaaataataa aaaattggag cgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt catgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DADGHT010000120         6390 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.122, whole genome shotgun sequence.
ACCESSION   DADGHT010000120 DADGHT010000000
VERSION     DADGHT010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.122"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            330..1175
                     /locus_tag="JX887_002538"
     CDS             330..1175
                     /locus_tag="JX887_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1258470.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="JX887_002539"
     CDS             1456..2676
                     /locus_tag="JX887_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAX1258471.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="JX887_002540"
     CDS             2673..5393
                     /locus_tag="JX887_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1258472.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="JX887_002541"
     CDS             5377..6321
                     /locus_tag="JX887_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAX1258473.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2379 a          987 c         1231 g         1793 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt
//
LOCUS       DADGHT010000121         6373 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.123, whole genome shotgun sequence.
ACCESSION   DADGHT010000121 DADGHT010000000
VERSION     DADGHT010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.123"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            598..1287
                     /locus_tag="JX887_002542"
     CDS             598..1287
                     /locus_tag="JX887_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1258474.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="JX887_002543"
     CDS             1274..2482
                     /locus_tag="JX887_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1258475.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="JX887_002544"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="JX887_002544"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAX1258476.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="JX887_002545"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="JX887_002545"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAX1258477.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
BASE COUNT         1939 a         1198 c         1230 g         2006 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgcggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtgt attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gta
//
LOCUS       DADGHT010000122         6294 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.124, whole genome shotgun sequence.
ACCESSION   DADGHT010000122 DADGHT010000000
VERSION     DADGHT010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.124"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..496)
                     /locus_tag="JX887_002546"
     CDS             complement(<1..496)
                     /locus_tag="JX887_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1258478.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEF"
     gene            807..1799
                     /locus_tag="JX887_002547"
     CDS             807..1799
                     /locus_tag="JX887_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1258479.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            1859..3280
                     /locus_tag="JX887_002548"
     CDS             1859..3280
                     /locus_tag="JX887_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAX1258480.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            3273..4772
                     /locus_tag="JX887_002549"
     CDS             3273..4772
                     /locus_tag="JX887_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAX1258481.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            4811..6205
                     /gene="uxaC"
                     /locus_tag="JX887_002550"
     CDS             4811..6205
                     /gene="uxaC"
                     /locus_tag="JX887_002550"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAX1258482.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         2039 a         1179 c         1284 g         1792 t
ORIGIN      
        1 tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg taatgcttcg
       61 ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc ttagcgatta
      121 gtttacgtga ttgattttcg tacagttcca tgagaatcgc ctgcttcagt tcctttgtta
      181 gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtccgtcca caatcatggc
      241 agagaaaacg ggtacgtttt aattctaaaa tagtcaactt ttctttgact ttcaacatct
      301 gagtgcgtgt cgtataggaa ccgttgcgga taatacgaat cgatccacag tgttcacaat
      361 gggaaggtga gtcatccaat ctccctttaa taaactgcgc ttgaacgcct ttatattctt
      421 tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg agtaattttc
      481 tagtatgatt atccattgag agactccttt ggtagggtga cgttttggtc gactaaattt
      541 taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa aagtgttagt agaaaatcgc
      601 tttcgatttt ccaccaacac aaaatattat agaaccctaa ttaaatgagc attccccgct
      661 ttcaagaata gcataattaa aaataaaaat ccaagtaatt tttaacgtgt gcaatctttt
      721 catatcaaag atctattgac ttatcgtagt tatcgtaata tgatgaatgc gttaacaaaa
      781 agtgaaaaag taaggaaaat gatggaatgg taacgatcaa agatatcgct aaagcagctg
      841 gcgtttctca tacgacagtt tctcgtgctt tgaataacag cagtttaata aaaaatgaaa
      901 caaaacaaaa aatacgacaa ctagctaagg aaatgaatta ttcgccaaac tatagtgcaa
      961 aaggtttagt gaatcaaaaa aaatatctaa tcggactatt tttctcaagt ttgcataaag
     1021 gaacttcatc aaatttccta gcagattcca ttgcaggcat ccattcagta ttagacacaa
     1081 attacagttt atctgttgaa agtatcgatg ttgttgattt aacagaaatc aacctgcaac
     1141 gctacgatgg actgatcgtt atgagtcaaa gtgatgatga tcagcctttc atcgactatc
     1201 tcaaagaaaa agaatttcct ttcgttgttg tcaatcgtca catcaatgat ccagcggtta
     1261 tcaacgtcac tgccgatgat gcggccggtg ttatgcaggc agtagattac ggtattggat
     1321 gcggacatac gaagatcgct tatattggcg gaaagaaaaa ttttcgttcg acaaaagaac
     1381 gggaaaaagg ggtattgaaa agtctaaaaa aagcgagcat ccctgtcaat ctagcctatt
     1441 ttttaacagg agattacagc ttagaaagcg gcctccaaaa catggaatac ctattatcac
     1501 tttctgacct gcctactctg gttttttgcg gcaacgacga catagcgatt ggtgcattga
     1561 gagctgtaca tttagctggc ctccgtgttc cccagaacat ttctctgatc gggttcgatg
     1621 attctccagt cgtctcctat ctcaatccgc cgcttaccac cgtacgtaag cctttgaaag
     1681 aaatgtgtca agaaggaaca aagcttttac tagatttgat cgaaggcagg acgatcgaac
     1741 aatctaaaat tgagctctcc accttgttga tccttcgtga gtcgatcaat tacttgtaaa
     1801 ctacaagtaa ttttatataa aaatgttaac gtgtgcataa cacagaaagg aagtttatat
     1861 gaaaaaactg acaaaagaat tagtgaaaaa aaacgaagca cctgtaaaag ttcttcagtt
     1921 tggtgaaggc aattttatgc gtggatttat tgattggcag attcagcagc tgaataacca
     1981 acaattgttt aaaggtaatg ttgcaatcat tcaaccttta gaacaaggtc ttggaaatat
     2041 gatgaaccag caagataatt tatatacggt cattttacaa ggactcagca atggcgaaat
     2101 cgttgatact tccgagatta tcaccgtagt agaacaaatg atcaatcctt atgatgaatg
     2161 ggatgcttat ctatctctag cagaaaatga cgacttggcc tatatcgtct ccaatacaac
     2221 agaggcagga atccaattcg tggagactga taatttaaca gatactcccc cacagagctt
     2281 cccgggcaaa ctgacagcct ttttataccg acgtttcaaa ttaaacaaag ctggctttac
     2341 catcattcct tgcgaactga ttgacagaaa cggcgaacgt ctaaaagaaa tcattttacg
     2401 ctacgcagaa aaatgggatt tagaacctgc ttttgttgag tggttagaaa aagaaaatgt
     2461 tttctgttgt agtttagttg atcgcatcgt cccaggttat cctcgcgaag atgcaggtgt
     2521 tttcaatcaa cggcataact atgaagatca attgatggtc aaagcagaac cattcatgct
     2581 ttgggtgatc gaagggccta aagaattgga gaatcaacta ccattcaaac aggctggctt
     2641 gaatgtcatc atcacagatg atatgactcc ttatcgtgaa cgtaaggtgc atttgcttaa
     2701 tggaccgcat acagcgatgg tccctcttgc tttgttggcg gaattggaaa ctgtagaaga
     2761 agtaatgaaa gatcctttat tctccgcata tgttgatcag ttattcaatc tagaattgat
     2821 tcctatgctt tctttaccta aagatgaatt agccatttat gctgaccaaa tcaaagaacg
     2881 tttcttgaat ccttttgccc atcacaaatt agaagcgatt tcattaaata gtgtttcaaa
     2941 gttcagcacc cgtctgcttc cagtgttcaa gaagtatatc gaagaacaaa atcaggtacc
     3001 accgttaatc actgtttcac tagctgcgct acttcttatg tatcgaggcg atcaagtaaa
     3061 gccacatgat gatgaaaaga cgataagcga atttactgat gcttggtctg ataatggaac
     3121 agctattcct cgattattgc aaaacgctgc gctttgggga gaagatttgt ctcaaatacc
     3181 gaatgtgaca gatacagttc aagaaatagc tgcaaagatc gatcaaaaag gtgtccggtc
     3241 agtattacaa gaaatgaaag gaacgatggt ccatgcttga aaccctgcaa ccaacaatga
     3301 aattaaatcg acgagacagt gtggtcgtcg cattaacccc tattccaaaa caaacacaac
     3361 tgacgattga tcagcaaacg atcaccactc ttgaagatat cccgcaaggt cataagattg
     3421 cattgggtga tttgaaagct ggagacaacg tgatcaaata tggctatcca atcggtcatg
     3481 tgacgacaga cgtaactgcc ggtcaatggc tgcacactca taatgtaaaa accaatcttt
     3541 ctggtgaatt ggattatcga tatgaaaaag atgtccatcc aagtcattac ctttttgaga
     3601 accgaacatt tcaaggttac ttgcgaaaaa atggaaaagt agggattcgt aatgatttgt
     3661 ttttagtacc taccgttggg tgtgtgaatg gcattgctga actgatcgtc aaacagttca
     3721 aggaaaaaca tccagatctg ggacagtttg accatattac gattttaaag catccttatg
     3781 gctgttcgca gcttggaaaa gatcatcaaa atactcgaga aattttagcg gacgcagtaa
     3841 atcatcccaa tgccggagga gttttagtat ttggattagg ttgtgagaac aatacagttc
     3901 ctgaattcaa aaaaatttta ggtgaatatg atgaagaacg agtgaaattt ctagtggctc
     3961 aagatgttta cgatgagatc gaacaaggtg tggctctatt agaagagctt ttaacagcgg
     4021 cggaaaatga ccagcgcata tcagtcccgc tctctaagtt gaatgtcggt ttgaaatgcg
     4081 gcggttctga tggtctatcg ggaataactg ctaatccttt acttggtgca ttttctgact
     4141 acttgattgc tcaaggaggc agcacgatct taacagaagt gccagaaatg tttggcgcag
     4201 aacaagtatt gatggcacga gcggaaaatg aagaagtttt tgactcaatc gttgacttga
     4261 tcaatgactt caaacagtat ttcttgtctt acggggaacc agtttacgaa aacccatctc
     4321 ctggtaataa agcaggtggg atcactacat tagaagataa gtctttaggc tgcacgcaaa
     4381 aatcaggaag ctctcctgtc gttgatgtgc tacaatatgg cgaaaaaatc agaaaaccag
     4441 ggcttagttt attgcaagct cccgggaatg atcttgtagc tgcctctgct cttgcttcat
     4501 ccgattgcca gttggtcttg tttaccacag gaagagggac tccgtttggc tcatatgtcc
     4561 caacggtcaa ggtatctacg aatacaactc tttttgaacg caaaggtcat tggatggatt
     4621 ttaatgcagg cgtcttatta gaacaaccaa tggaagtaat cttagaatcg tttgttcaaa
     4681 aaatcatcgc tgtagctagt ggagaagaaa cgaaaaatga acaaaatgac gttcgagaaa
     4741 ttgccatttt taaaaacgga gtaacacttt gattttcata aaacagtata aaaagaaaga
     4801 aggaagattt atgtttttat ctgatgattt tttattaaaa gacgattggg cgaaaaagct
     4861 ttaccattcc tacgcaaaaa acatgcccat tattgattat cactgtcact tagatccaaa
     4921 agaaatttac gaaaacaaca atttcagcaa tctgacagaa gcttggttag gaggcgatca
     4981 ttacaaatgg cgcttgatgc gagcttgcgg cgtgcctgaa gaaaaaatca caggaaatgc
     5041 ttctgatttt gaaaaatttt tagcttggtg tcaaaccgta ccaaaaatta tcggaaatcc
     5101 gctttacagt tggtcacatc ttgaattgaa gcgtttcttc ggtattgact tgttgataaa
     5161 tgaagaaaat gcagagaaaa tttggacaca agcaaatgaa attttggcag ctcctgattt
     5221 tcgccgtcgg gaaatcgcaa aaaaatcgaa tgtagaagtg atttgtacaa cagatgatcc
     5281 cgcagacgac ttgcactatc atcagttgct tgctcatgaa gaaccagatt tgaaggttct
     5341 accttcattc cgtccagata aagcactcaa tattgaaaaa gaaggattta atgcatgggt
     5401 cacactactg gaagaagcag ctgaccaaac gatcaccacc tatcaagaac tgatagaagt
     5461 cttagggcag cggatagaat acttccatca acatggatgt cgtgtttccg accacgcttt
     5521 agacatctta cgctataaag aagcggatga aacagtatta gaagagattt ttcaaaaagc
     5581 acgagctaac aaactattat cttcagatga aatcgatgct tatcttacag aaacactgat
     5641 acatttgacc cacttctatc attctcataa ttggacgatg cagctgcaca tccatgctta
     5701 tcgtaactgt aatacacaaa tgttggaaaa attagggccc gataccggct atgatggaat
     5761 gaatgatctt tctttgacta ttcctctgca aaaattattg aaccgtgcag aagaaacgga
     5821 tcagttgcca aagacgatcc tttattcatt gaatccgaat gactatcctg cgattttagc
     5881 tttgatgggc tgtttccaaa aagaacagaa tggaaaactg cagttaggtt ctggatggtg
     5941 gtacaacgat actcgagctg gtatgcgcga tcaattgaca caatttgctg atggtagtgc
     6001 tttggggaat tttgtcggca tgctgacaga ttcaagaagt ttcctgtcct acactagaca
     6061 tgaatatttc cgtcgtgttc tttgtgaatt tttaggcgaa atggtcatgc gaggagaagc
     6121 acctgaagat gaacaacttt taggaagtct agttcaagcg attagttata caaatgctaa
     6181 aaattacttt ggcttttttg cctaattgat taatagtaac agtaacgaat caaaaacagg
     6241 atagtgaaat aacggaatcc gtttatccac gttttagaga agaagacgga ccaa
//
LOCUS       DADGHT010000123         6265 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.125, whole genome shotgun sequence.
ACCESSION   DADGHT010000123 DADGHT010000000
VERSION     DADGHT010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.125"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..117
                     /locus_tag="JX887_002551"
     CDS             <1..117
                     /locus_tag="JX887_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258483.1"
                     /translation="ENGTTNQRAQHFASGTYEQNKEKIEEIMTRKILDLWEG"
     gene            124..750
                     /locus_tag="JX887_002552"
     CDS             124..750
                     /locus_tag="JX887_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1258484.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            750..1214
                     /locus_tag="JX887_002553"
     CDS             750..1214
                     /locus_tag="JX887_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258485.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            1409..3718
                     /locus_tag="JX887_002554"
     CDS             1409..3718
                     /locus_tag="JX887_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAX1258486.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            3730..4434
                     /locus_tag="JX887_002555"
     CDS             3730..4434
                     /locus_tag="JX887_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAX1258487.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            4431..>6265
                     /locus_tag="JX887_002556"
     CDS             4431..>6265
                     /locus_tag="JX887_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258488.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
BASE COUNT         2139 a          981 c         1406 g         1739 t
ORIGIN      
        1 gaaaatggca caacaaatca acgtgcccaa cattttgcaa gtggtacgta tgaacaaaac
       61 aaagaaaaaa ttgaagaaat tatgactaga aaaatacttg atttatggga agggtgattt
      121 taattgggaa aacaagatac tttttatttt gaaggattgg acgacatttt aattgcgatg
      181 atggcaacgc cagattctgt tggaactgca ccgacttata gtgaagtttt acgattgcca
      241 attgccacaa aaatcggtgt caaagggaat ggaacagcat tagaaaaatg ggcatccagc
      301 aaaatgtttc gtcgtgtgtc gcgagaaaca aaacatgaac ttgcgttgga tcacgtgggt
      361 attccgatag aagtgatgga tgaaatcaaa ggattagttg ctaaaagcgg agtaacgttt
      421 agcaaaaata ccgcacgaga atttccgtac ttcgcctttg gatttattgg aaatattgaa
      481 aatggcggta aaaaagcagt ttggtatcct aatacacaac tatccaatgt gattgacgaa
      541 gagtatgcca ctgcagagga agaaacaaaa attgacgatg taactgcaaa tctggtttcc
      601 atcggactga aatacaataa tgtgatgtat gcaagttttg attcaaatag agacggagct
      661 tctctagaat tatttaataa attcattgct caacctgtat acgatgaaga acagtggaaa
      721 acattggcta aagttggagg tgcgggttaa tggctcggtt atctgattat ggaattcacg
      781 ttgaagactt aaaaaattct gctgttgtaa ttattcaagg cgcagaattc cctatttcat
      841 ttactatgca aacgatggaa tttatagcag atgtgtatgg tggagattat tcgcaatttg
      901 aatctgatat gaacgccatg ctatctaaaa aagaaggaca aatttcttct gctaacttat
      961 cgcctagtga tctaaaaatc atgcgtgcct tgatttatgc catgctgcgt actggtggtt
     1021 tagaggaaga tccagaaact attttcaaat ttttgggaat gagtggagag gtgttgtctg
     1081 cttatagtac ctgtatggaa atttttgcta gccagacatt tcaggtggaa gacctaaaaa
     1141 aatccaagaa gccacaagac tttcaaaaag cgcaagcaaa aagaaagaaa aacaaaaaga
     1201 atcggaagag ataggaactc cttggagttt ttatatttac gttgctctca ctctattgaa
     1261 ttggagtgag agtttctttt taaagtctac acctaacttg tggctcaaat cttatttaca
     1321 gtggttacaa caaaacaccg attttgaacc acctcaatct gtaactatgg ataaatcgcc
     1381 ttggtggtag aaaggagcgc taagataaat ggctggtaaa gaatctgatg tcgttcttaa
     1441 ttttaaaacg aatggcgaag tcagttattc gaaaacaatc aaagaaatca acaaagaaat
     1501 gaacttagcc gctgccgagt acaaaaacca agtgtctgcg atggacaagg atgcaactca
     1561 aacagaaaaa ttgcgagcgg ctaaacaaaa attagaaaaa caattaggat tggctgaaca
     1621 acgatctcaa atgctgagag aggaatatga aaaatctgtc aaagaaaccg gtgaatattc
     1681 tgctgaatca gaaaaacttt ataaacaatt actcaattct gaaaccggag aaaataaact
     1741 tcgtacagca ttagaacaga cgaacgatgc acttaaagaa caaggtgacg tttctgttga
     1801 tacagcaaaa aaactccaga aaatcgaaga aacaggtgag aaagtaaaag gcgttggtga
     1861 aaaaatgtct gttggagtaa ccgcgcctat tgtagcggca ggagcagcag gacttgcagc
     1921 atttggtgaa gttgacgagg cacttgatac catcattaca aaaaccggag caacaggtga
     1981 tcaagctgat agactttcac agtctttcaa aaacgttggt tcaaatactc atttaccttt
     2041 acaaacggtt ggggaagcta ttggtgaggt aaatacacaa tttggattca tggataaaaa
     2101 actggaagat tcaaccaatt atctcctaca gtacgctgaa atcaatgata cagatgtttc
     2161 gcaatcagca atatctgctc gacaagctat tgatgcttat ggactagaat atgatgattt
     2221 gaattctgtc cttgatgtaa caacgaaaac atcgcagaat actggtcaat ctgtagacga
     2281 cttgatgcaa aaagcaattg atggcgcacc acaaattaaa caattagggt tgagctttgg
     2341 tgaaggggtc actttacttg gacaatttga gcaatctggt gttgattcaa gcgcagcttt
     2401 aagtagttta tctaaagcaa cagtggctta tgcgaaagac ggaaaatctt taagtcaagg
     2461 actagaagaa ctacaagaca aggtaaaaaa tgcaggttct gaaacagaag ccatcaatgc
     2521 agcagcagaa gtattcggga ctaaaggcgg tcctagaatg gccgatgcaa ttcgtagagg
     2581 tactttgaac ctggaagatt tagcaaaaac tgctggagaa agtgggggag ctgtaggaga
     2641 cacattcgat gctactctcg acccaattga tcaagccgat caagctatga acaatgcaaa
     2701 attagcaatg gctgacgtag gtgaagcagt ccaagtaagc cttttgcctt tttttgaaaa
     2761 agcaacttcc ttattacagg aattctctaa atggtggggg tctctagatc aagatacaaa
     2821 gaattggatc ataacaattg ctggtatagc ggcagcagtt ggaccagtac taatcgttct
     2881 tggttcactt atgggatctg ttacaaaaat cgttggggaa gttaaaagtt ttataggagt
     2941 ttggcaagga cttgctggtt tatttggaat gtcgggaggc tggtttgcat tagcagttat
     3001 agctattggc gcattagtta ctggactaat ttgggcatat aataacgtta aatggtttca
     3061 tgatggagtg aattctttct tcaaaggtgt ttcagatgta gctgttgaaa tatttaattt
     3121 tttaagtggt tattttggtg gatttttcga tggtgttata gcaaatttca ataattttta
     3181 taatgctgga aaacgaattt tcagtggttt tctagatttt atcactggag tatttacagg
     3241 gaattggtca aaagcatggc aaggtctagt tgatattttt ggaggtattt tcgatggtat
     3301 tgttgctgta gggaaagctc ctattaatgc catgattgga ttgatcaatg gatttattgg
     3361 tggattgaat aatataaaga taccaaaatg ggttcctggt gtaggtggaa aatcattttc
     3421 tatttcaaaa ctgccttatt tagcacaagg cggtcatcta atcaatggac aagcgattgt
     3481 tggtgaagct ggacctgagt tactgactgc caagaatggt aaaaccacag ttactccatt
     3541 atcagacgaa gaaaaacgca aagggatcag tggaagagtt tctggaggta gcattgaaca
     3601 gcatatacac attggcaaag tcgatgcaaa caatccatct gagttagatc gtatgaatcg
     3661 taaatttgct aaagcaaaca aacaggctat tcgtgatttg ggaggtgttc ctatttgagt
     3721 cgacaattta tgaatccaga tgaaccaaat tttatttgga aaaatcggaa tgcagtaatt
     3781 gatatgaatt gcatcattga ggcagagctt ccagatatta tgccgaacaa gcgatacgaa
     3841 acttacacga ttcagggccg aagcggagaa ttgacggaga cgtttgatga ctatgaacct
     3901 tttgatttgg aaatagaagg gatcactatt ccacattcga aactgagaga agtcaaacga
     3961 tggctcactg gtaaaagcca attaatcaca cataatgatc cagacaagta tctagaggct
     4021 atctgcagca tggataaaga agtccctttc gaaaacgagt ggggcttctt ttatacattc
     4081 gatgttactt ttcgttgtca gccactcaaa agaaaaatcg gtgaagcacc taaaattttt
     4141 cattctagtg ttatggatat ttttgatcat ggtgacgaaa ttgcacatcc ctatctggaa
     4201 atagaatcga acggaggaga tataacgatc gctgtcggtg ataaaagcct aacaatactt
     4261 aatacgttag ctgcaacaat cgtggttgat actcagcttg gaaaagcaat acaagaaggt
     4321 ttgaatttat ttacgcgtgg tgattggcca gtattgcagc ctgaatggaa tcaggtaaaa
     4381 atatccggaa aatttaaaga agtgcggttt tggaatagga gtgtgtatct gtgacgcaag
     4441 aatttattta tgcttataaa aaaatgccag atgatttgag cgtgaacgga gcgtcgttag
     4501 ttgattggga agatttgcca gaaatcaatc gtgtgctgaa tggccaatat cgtttttatg
     4561 gtaactattc aagaagcgga cagtatcgct cttatttaaa aaaaggaaat tttataaaag
     4621 cgaaggtacc agatggatca tggcaatatt ttgaaattta taatgtcaaa aagaatttga
     4681 cctccgtttc tgtaacagct cggcatattg gttttatggc caataagaac tttattgtca
     4741 agtcgtttac ggataacggc aatgggtctc agatcatgac caatcttaaa aacagtttgg
     4801 catttgatca aaaatttaac tatctttcga atgtagggac aacgcaccaa tttacagcaa
     4861 gacaagtcgc gccagttgaa gcaatcattg gttcaaataa cggtaatcaa aatttgactg
     4921 gcgtgactag cgcggaactt gatatggata actatgattt gaaactggta aaacagattg
     4981 gatcagataa tggttttcgg attgattttg gcatcaattt agaagcaatc gaagaagaaa
     5041 ttgatgaaga atcaattgtc aatagtttgt atttggttgg cggtgttcct gataacgatt
     5101 atgatgaaga caaagaacct atcgaatatg gttatttaga aattgatgga gtaaccaacg
     5161 agaatcgacg tattgccaaa cgtgaaaacg gagattgtaa aacagttgat gaattgatca
     5221 aatggggcaa aaccttattt gacaatgatc gtatccatga gccaaaagct actcatacag
     5281 tcagtatggt ggcgttggaa cacacactcg aatacggtga catgtatcaa gagctagcgt
     5341 ctttacactt tggtgatgtc gctcatgtta gggcgaaaga gctagatatc gagataaaag
     5401 agcgtatggt cgaatacact tatttcccaa cgcttgggaa atataaggat attgttttag
     5461 gtaatgattt atcactgtac acttcggcag taaatactca agcacaagaa ttgaaaaaga
     5521 aaatcgacaa tcgaacagaa acgttagttc aaaatgtgtt gaatgcgacg gcatggatca
     5581 ctggtaattc tggtgggcat gtcgtttttc gtccagaaaa agctccatca gagattctta
     5641 tcatggatac tccaaatgtg gcgaatgcaa agcgagtgtg gcgttggaat ttaaatggct
     5701 taggttattc agacaacgga gtaaatggcc cgttcggtat tgctatcaca tcaaaaggag
     5761 aaattgttgc tgacttcatc aaagtaggaa caataaatgc agaagtattc gaaacttcct
     5821 ttaatgctta tggtgatgtg ttaaaacttg taaaaggcac gcttcaaatt tggaatgaaa
     5881 acaaaaaaat catggagcta accaaaaaag gtatggaatt ctggaataga aaagaatcca
     5941 ttggaacgat cggaacaaca gattcagcag gaaatccatt tccaaatgct gtaacaccta
     6001 cacctcttga ggaaaattct ttggtaatac gtacaaatgg cgatggaaaa tacattttaa
     6061 tttctccaac tgcagaaaaa ggatttgtgt tattaggaaa cggaaaagca tattatttcg
     6121 gtgatttaga tattcaggga aaacttactg ttagaggtaa agaagtgata ccaggacaaa
     6181 atggcggtcc atctggcgga ggagaaacac ctggtgggta tcctgatgaa ttaaaaacag
     6241 atgcagaaaa gagagcttgg agaat
//
LOCUS       DADGHT010000124         6226 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.126, whole genome shotgun sequence.
ACCESSION   DADGHT010000124 DADGHT010000000
VERSION     DADGHT010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.126"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            133..633
                     /locus_tag="JX887_002557"
     CDS             133..633
                     /locus_tag="JX887_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAX1258489.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            730..2577
                     /locus_tag="JX887_002558"
     CDS             730..2577
                     /locus_tag="JX887_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HAX1258490.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2580..3476
                     /locus_tag="JX887_002559"
     CDS             2580..3476
                     /locus_tag="JX887_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1258491.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3526..3915
                     /locus_tag="JX887_002560"
     CDS             3526..3915
                     /locus_tag="JX887_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAX1258492.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3902..>6226
                     /locus_tag="JX887_002561"
     CDS             3902..>6226
                     /locus_tag="JX887_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAX1258493.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLE"
BASE COUNT         2104 a          924 c         1335 g         1863 t
ORIGIN      
        1 gagttttcca aactgattgg cttcttggtg attgctttga ttgcggtagg tctggtcttt
       61 aatgcttctg gtgtgaagga tgtcttactc aatttgttta accgaattgt cggtgcctga
      121 gggggaatca caatggaaca gatacgtgtt tatattgcga accttggaaa atacaatgaa
      181 ggtgagttgg tgggggcatg gtttacccca cccgtcgatt ttgatgaagt gaaagaacgg
      241 attggattaa atgacgaata tgaagagtac gcaattcatg attatgaact gccttttgag
      301 attgatgagt atacaccaat tgaggaaatt aatcggttgt gtggtttagc ggaagagctt
      361 aaaggaacgc caattggtga ggtcgcttca gagattcaac atgccttctt caattctttc
      421 gaggaaatgg tagagcatgt ggatgatatc atctattatc ccgattgtaa tgacatgagt
      481 gatgtagcgt attacttgat tgtagaagct ggtgatttag gcgaagtacc agaacacttg
      541 aagacgtata ttgattttga tgcgtgtggt cgagacttgg agattggcgg gaattatttg
      601 gttacgagtc gaggggtttt tgaactaatg taaatcattt gttagaattg accagaaatt
      661 tctatcgtac ttttactttt ctatttgata tactgaaata gaaaatattt gttgataggg
      721 gtgttactaa tggttggcaa taagtggtac aaatgtgatc ttcatattca ttcaactgcg
      781 agtcagtgct ttcaggataa aaaggttact gctaaggaat gggtagaaga atgtttaaac
      841 aaaggactcg attgtgttgc attaactgat cacaatacag gggaaaatat tgatgaatat
      901 aagaaagtgg ctatcgaaaa tggcttagat ttttttcctg gagtggaatt aacgtgtgga
      961 gaaaatggaa ctcatttact agtcctattt gataaaagtg catgtacaaa tgatatctct
     1021 gatttcttaa ccaagatggg tataaaaaga gaggattggg ccagcgctgc agcttgctca
     1081 atgaaatcag ttttagaagt tattgatttt gctgagcacg agggcttgct cgttattcct
     1141 gcacatatag atgagtttaa tggaatttct tcagcaaaat ttggaaatct aggaaagata
     1201 tttgaatcag aaaatatata tgcagtacag acggttcaaa aagaattttt tgaaaatcgc
     1261 tcacaaatga ttccctcatc taagcgtgac actatctatg atagtgtgaa tgccagatat
     1321 gatggtagag ttggaaaaga tactttggaa tcttggtata aatcagttgt tgaggcagaa
     1381 aaaaataata tgacatttct tagcttttct gataacccac actcgaaagg aaattcaaaa
     1441 catggacttt ggggaatagg cacaagatat tcctatataa aaatgaagga cgaacctgac
     1501 ttgggatcac ttcgcgatgc tttaatgcta ggcgaaactc gagttcattc tgatttttct
     1561 aatttctcca ttaatgaaaa tgaagtttta ttggaaaaat taagcttttc tgggaccact
     1621 cttagcacaa aagaagttgt agtcgaattc agcgataatt taacttcaat tattggagga
     1681 agaggaacag gcaaatcttg tattacaaga ttcttggtct atgtccttgg aaaggaagca
     1741 gaacttgatc aattttctga aatacaaagt gattatcaga actttgcaca aattgaacat
     1801 aatggctctg gaatattttt gaaggataca attgtgaaac tgaatatttt ctataagggg
     1861 acaaaatatc aaataataag aacacaggat agacattcta tttatgaatt tacacaagag
     1921 aatggtctgg ttgaaaaaga aacagaacgg ttgagaatga tttccgataa ggtgagtata
     1981 tactctcaaa aacaaattta tgaaatttca aaaaatcaaa ctagtatact agaattacta
     2041 gatggatata actctgattt gatttcagag tataaaaatg agattgaaac atgtgtaaac
     2101 gaaataagaa aattaaattg ggatattgtt tctgtgaaaa aagaaataca agataaggcg
     2161 aaggtagagc ttgaaattga agatttaaaa aaacaagtag aaaagctatc tcataagagt
     2221 tataaagatg tttatgatga gtattcaaaa gagacagata tttataggga actgaaacgt
     2281 gatgtggagg cacttaagga aattcccaaa aatctaactg atagtgttga caaaattgac
     2341 tttggcaatg gtataaaagt tacagacgaa attgatgaac accgcggaga attgattaag
     2401 aatttagtga ccaatcgggc taagattcaa acaataatta atgaaatgtc agatgaaatt
     2461 gatagttata gagcagagct gaataaatca gattggaaag ttaactataa tgaggtttca
     2521 aagaggtatc aaagaggtat caaaaactta gtgaagagtt atctcaagat gaattaaaaa
     2581 tgttacaaaa ccttgattct ttatatcaat ctttatcaaa aactgaagag cgattggaag
     2641 aaattattca acaagaaata aagcttaaag attaccaagt tgaggttgac tcagcaatgt
     2701 caagaatgaa taaatcatat caaaatctct attctgagag aagtagttcc tcgcgcgaaa
     2761 ttttttctga tattacagga atagaggcta ctattcaacc aaatagggat ttcaataatt
     2821 atgttaaaga gctcagagct tgtattaata aggaggacac ttttgacagt gagtttggat
     2881 ctcttattga taagctgaca aaaaattcca ttactaatca agatatatat aatgacatac
     2941 ttgatataag agttagtggg gaaagtagta ttttttcaga taaaaaatta atcaattcta
     3001 taagaaaatt gaatgatgca caagttcttg aattacaaac ccttaagcca aatgatttag
     3061 tagttatccg acttgaacta aatggaaaaa aagttagttt atcgaatgct agtgctggtc
     3121 aaaagacatc tgcaattctt tctatgattt tggcgtatgg aaattcacca ctcatattgg
     3181 atcagcctga agatgatttg gatagtcaat taattaataa cttaatcgta agaagtatca
     3241 ttacaaaaaa ggaaaacaga caaattttaa ttgtaactca taatgcaaat atcccagtta
     3301 atggtgattc agaatggttg attagcatgg gagattcaaa agaaatatcg gctgatcagt
     3361 gcgggtcggt agatgaaccc aatatcaagc caagaatatg tactgtgatg gaaggtggcg
     3421 aggatgcttt tacaaataga gcgaaacgct atggttttaa acaaattgta gaataacact
     3481 agagggtgag acatattatt atgtccgccc tttttaggag gaaaaatgaa aaaaataaaa
     3541 agctatacca gtatctgggc agttgaaaaa gtcatttacg caatcaatga ttttcagttg
     3601 ccttttcctg tgacttttaa ccaaatggct tggttcgttt tatctttact gtttgtcatc
     3661 gtatttgccc atgtgcctcc actatctatg atagaggagg tctttttaaa atacttaggc
     3721 ataccggtgg ctgtcacttg gtttatgtcg caaaagacgt ttgatggcaa gaaaccactg
     3781 ggatttttac gatcctttat cagctatcac ttgcgattta aggtgacttt tgcaggaaag
     3841 aaagtcaaag aacagaagaa acgatgggat gaacccagta ctcttgtaag gagtgtgaac
     3901 tatgtatccg attaagtata ttgaaaataa tctcgtcttt aaccaagaag gcgagtgttt
     3961 tgcctactat gaattagtgc cttacaatta ctcctttttg tcacccgaac agaaatttca
     4021 agtgcatgat aactttcgcc aactaattgc gcaaaatcgt gaaggcaaga tccatgcgtt
     4081 acaaattgcc acagaaagta gtattcgcgc cacacaagaa cgatcaaaaa aagaaattac
     4141 cggtagactc aaagaagtag cgaaacaacg aattgatata cagacagatg cattagtatc
     4201 catgattggc gatagtcaga ttgattatcg cttttttatt ggctttaaac taattgcgac
     4261 agatgaagaa gtcaatctaa agagtctcaa gaaatctttc ttttctgggc ttcaagaatt
     4321 tgtctatgga gtgaatcatc atttgatggg cgattttgtt tccttatcca atgaagaaat
     4381 tcgctgctat tctaagcttg aaaaattaat ggaaagcaaa ttggctcgaa gatttaaagt
     4441 caggcgagtc acaccgagtg acctgacgta tttgattgaa catatttatg gcgaaaaagg
     4501 gataccgttt gaagaatacg aatttcagct accaaagaaa aagctaaaat cagaaacact
     4561 ggtgaaacgt tatgacttat tacgtccaaa tcgttgttta attgaagaaa aaccaaggtg
     4621 cttacggatg gaacatgaga atcatgagtc gtacgtagcg tatttaacaa ttaatacaat
     4681 tgtgggggag atggaatttc cttcctcaga acttttctat taccagcaac aacaatttac
     4741 attcccaatc gacacaagta tgaatgtaga gattgtgacg aataaaaagg ctttagctac
     4801 cgttcgtaat aagaaaaaag aactgaaaga tttagacaat catgcttacc aatctgacaa
     4861 tgaaacgaat tccaatgtct tagatgcttt ggattccgtg gatgaattgg aaaccacctt
     4921 ggatcagtca aaagaatcta tgtacaaact gagttatgtg gttcgagtga gtgccgaatc
     4981 agtggatgaa ctaaagcgac gctgtgatga agtgctcgat ttttatgatg ataccaatgt
     5041 aaaactagtc cggccctttg gcgatatgat ggggctacat gaagaattct taccctcaag
     5101 taaacgatat atgaacgact atattcagta tgttacgtct gattttttgg cggggcttgg
     5161 ttttggggct actcagatgc taggagaatt agaagggatt tactttggct acaatgtgga
     5221 tacaggtcgt aatgtttacc tgaaaccggc attggcttca caaggagtca agggttcagt
     5281 aaccaatgcg ctggccgccg ctttcctggg ttctcttggt ggaggtaaat cctttagtaa
     5341 caatctctta gtctactatg ctgttttgtt cggtggtcaa gctgtgattg tcgatccaaa
     5401 aggggagcga ggagggtgga aagaaacctt gccagaaatt gcggatgaaa tcagtatcct
     5461 caacttgacg agtaagtcag aaaatcaagg tctgcttgat ccttatgtga ttatgaagaa
     5521 aaagaaagac tcggaaagtt tagcaattga tattctgact tttttaacag gaatttcaag
     5581 tcgagacggg gagaagtttc ctgtgttacg taaagccatt cgaacggtga ctcaaagtga
     5641 tcaacggggg ttattacaag ttattaacga attgcgaaaa gacgggtcac caatcgcgga
     5701 aaatatcgcc gatcatatcg agtcctttac cgattatgat tttgctcatt tgcttttctc
     5761 agacggctcg attacccaat cgattagttt agataaacag ctaaatatca ttcaagtggc
     5821 ggatttggtt ttaccggatg cagaaacgac ttttgaagaa tataccacca tggaattgct
     5881 tagtgtttcg atgctaatcg tcatttccac ttttgccttg gactttatcc atagtaaccg
     5941 agaaatcttc aaaattgtcg atttggatga ggcttggagt tttcttcaag tggctcaagg
     6001 aaaaacgtta tcgaataagc ttgttcgtgc tggtcgggcc atgaatgctg gggtctattt
     6061 cgtcactcaa aatagcgacg atttattaga tgaacgttta aaaaataata tcgggttgaa
     6121 gtttgctttt cgcagtaccg atattcatga aatcaagaaa accttggaat tctttggttt
     6181 ggatcaggag gatcaaagca atcaaaaacg cctgcgagat ttggaa
//
LOCUS       DADGHT010000125         6174 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.127, whole genome shotgun sequence.
ACCESSION   DADGHT010000125 DADGHT010000000
VERSION     DADGHT010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.127"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            725..811
                     /locus_tag="JX887_002562"
     CDS             725..811
                     /locus_tag="JX887_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAX1258494.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1622)
                     /locus_tag="JX887_002563"
                     /pseudo
     CDS             complement(932..1622)
                     /locus_tag="JX887_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1629..1907)
                     /locus_tag="JX887_002564"
     CDS             complement(1629..1907)
                     /locus_tag="JX887_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258495.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1867..2781)
                     /locus_tag="JX887_002565"
     CDS             complement(1867..2781)
                     /locus_tag="JX887_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAX1258496.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2763..3143)
                     /locus_tag="JX887_002566"
     CDS             complement(2763..3143)
                     /locus_tag="JX887_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAX1258497.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3593..3880)
                     /locus_tag="JX887_002567"
     CDS             complement(3593..3880)
                     /locus_tag="JX887_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAX1258498.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3900..4124)
                     /locus_tag="JX887_002568"
     CDS             complement(3900..4124)
                     /locus_tag="JX887_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HAX1258499.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4764..5297)
                     /locus_tag="JX887_002569"
     CDS             complement(4764..5297)
                     /locus_tag="JX887_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAX1258500.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5318..6160)
                     /locus_tag="JX887_002570"
     CDS             complement(5318..6160)
                     /locus_tag="JX887_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAX1258501.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1634 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa atataacccc tggcaataaa
     1501 aacctcttaa atcgaatttt agagcctttt aatgaatatc ttgtttgata agccttatag
     1561 ctaagccaaa taattcctaa aatactggca aaaatgagta gatagggtaa atagaatgcc
     1621 atttctattt attctcccca taccagccaa aaggctaaca gtgtcatgat taagcaacat
     1681 aagggggcaa gaatatccat tgatcgctgc ataattactt ttttctgttc tttatttcgc
     1741 tggtttaata gcgcatggtg gaattttttg acttgtgaat caattgtagt ttgtattctt
     1801 tctttggtat aaggtgcaag aaaagcacgt tgtttcttta tttcattttc tatgtcttgt
     1861 aacgttttag aacgataatt cttgttggta gtctgctcct ctttcaacgt gttggtcatg
     1921 gtttcttcga gtcggtctaa tttccggttg ttcagtcgta agagttcgtt gttctcttcg
     1981 tacttctttt gcagtttcgc gaatgctagc tcgagctctt cgtagctcgt tggttcgttg
     2041 ttgattgtag gctcgttctc gtctgtccag ctcatgtaaa atcgtctcct tttcgtaatc
     2101 ctttcctagt ttgttggatc gtactttttt ctttttgtgg atcaattcgt aagtaaaatt
     2161 tttcccacga ttcaagcaat gaatgccgaa tgttttaaga gaatcacaaa attggttata
     2221 cgttcgagtt tttttgtttt tcattgtttg atcaatcgca aaccgaattt cgtctttcca
     2281 aacaggttca tttttttctt ttaatttgat ttcagacatg gttcgttttt cgggtttctt
     2341 ccctcgttca gtgattgtta agtcatgttc aagacaaatc tcgtcattta ggtcataaca
     2401 tttgtttaaa aatgcttgac catgggcttg aaatttgttc ccagtttcca gattgacgga
     2461 gttaatgaca atgtggttat gaatatggtc tttgtctgta tgtgtgtaaa tcgcgatttg
     2521 gtggtcaggg gctatttttt tcgcatactc tgcccctagt tgattggctt tttcagcggt
     2581 aatttctcct ggtcgaaaag actggatcaa taagtgtgct tgtacacgat cgtcttttcc
     2641 atacagcatg cgaatttgtt tcatttcgct tttggcataa tcaatgtcac agtttatccc
     2701 tgttttgacg gttgctcgtg gttcggcgta attgatcgct cggctacaag aagtggttcg
     2761 gcttacttta actgttgcca tatcttttgt agctcctttt gcatgatttt taggttttcg
     2821 gataagcgtt gggcgtcgcc aggatcaacg tcgtgttggt gtgtgttgca ccacttggca
     2881 atttgattga tattcccgcc agctttggct aaatcgcgcg cgattgcctg agcaatgtct
     2941 ggcgccactt tcggtgtcac cagacgcgcg ttttgtgcct tggctttcac gaaagccggc
     3001 acactcattt gcaaagcttc agctgactgc ttcagctttg caaattcgga ttcgctcact
     3061 cgaaaactga tttgttttgg ctcggatcga taggtatatt ttttagaatg attgctagcc
     3121 aaatattgat tttgttcgct cataagtccc accctttcag tacgtcctac ggacgtatcg
     3181 ttcgcaatac cattgtacct aaaaaggtac aataagtaaa gctcactaaa gctcactaaa
     3241 gggcttggca agctctatat ttgctagcca aatacctacg tatttggtgc aaataaccgc
     3301 ttgtcaaagg ggcgcaagct cccccttgaa tccccctccc ccccactctc cacaatacaa
     3361 aaaagactag caaatgctag ccactttttg taaagtttcg cttgtttcac cttcggtgaa
     3421 attgttgcaa atcaataatt aggtagagct acattttttt cgttgttcaa agattcttat
     3481 gccatttact attaataaat ctataaatat gataattttt cggctctata atttatggga
     3541 ctgatgaatc agaattgatt cttcagtccc attttcattt tattccaaag aattaactcc
     3601 aaataccaat agaagcccat cctctatata cttgagattc cttactaaca atttcttgta
     3661 attctattaa agatttaggt aatccaaatt tatgttttaa aatatatctt ccaagaaaac
     3721 tacttaattt catactaact tcaccaacac tttttccctc actgatttct ttagaataaa
     3781 gaaagagctt ttcttttaag tcaggatagt catctatagt tgcttcattg tatactttac
     3841 taattgcatt taaaagtttt tcttctttag taaaatccat tataataacc tccctaccac
     3901 taccttctag gtgcccatgg accatgatta acccaaccat taacaataat ttttccaatt
     3961 tctcctttag cttgattcca atctacccaa catttttctt tgttacaata aagaccattt
     4021 ccatagtaag tagctgcatc aacttttatt cctgtaccga tgccagctag acaagttcct
     4081 aatattccta gaataacaca atgttttaat actttctttt tcatgattgt ttttcctttt
     4141 cgttttttta aaattgcttg ttatattaaa taatcttagt aattttatta tataacattt
     4201 tattatataa caatgattaa cgtcataaaa agtagttttg aattcataat cgtttaaata
     4261 aaattataag atcagttatt taaacagcta gtagacataa tgtgtatact accaagtaac
     4321 gcctgtacca agggatccag gcgctgattt tgtgaatttt tattggtcta ggttaaaagc
     4381 tctttttaag gcttggtttt ctgcggttgt ttctttctaa ttctttgtga atattgatcg
     4441 gtcatttttt aaatacttgt tatttttgtt tgtgtttgtt atgcttttta catatctcat
     4501 attcatttat tattcttttc taaggttaat aataggataa tctctttcag aaagactgct
     4561 cgtacgagca gtcttttctt atttatcaag tttttctaca aatacttcct cattttgact
     4621 gttgtagtaa ttaggattga gttttagttc ccctttttta tttcctttgt tggccactga
     4681 taataacatt gggctaaagc ttaatattcc tagtaggata gaaccgaata gcaagtgttt
     4741 ttttgtcata agtatttcct tcttcatttc catagctgcc accatttttt ccaattcttt
     4801 gtttgttcgt ccattgtttc tgttgcttca gaaagagtcg ttgaactatt ctctgaagac
     4861 tcttccgtat aagtcaactg cagttgctcc tgaagttttt cgatttgttg gttggcttgc
     4921 agggtgagtt gttgttgctg gtcgagtagt ttttgtatat gagaattatt ttgctctttg
     4981 agggcaagtt gttctcgtaa aaattcattt tcttcacgca actgatctag caacttgttt
     5041 gcaaccacgt ttttgtttgg tatataagca tttttatcgt tgttttgttc atgtttatgc
     5101 aacttatcta gcaacctttg attgtctaag ttgcgagcaa gttgcaatac tccagaacgc
     5161 aatacaacct tataaccacg ctcattttta gctatcatgg aagaatctaa tttttggata
     5221 tgtttcgata ttgcttgcct actcatctta aaaagatctg acaattcctt tattgtaaag
     5281 gtttcttgtg gttgcatact ggttgcctcc taggttgcta ctggaataaa ttatctaaat
     5341 cagataataa actttttttc tctttttccg aaagtgcgga ctctgtttgt ttttcaagag
     5401 cttttttctc tttttctagt tgtttgattt gttggaggag ttcaagttct cgtttcttct
     5461 gtttgatttt ttcgttaatt gttgtagcgg gttcttcgta ttctttttgt ttatcagcta
     5521 aagccaatgc tttattttgg tcttctttgg ttggtgcatg tttgttaaag tcgtctgctt
     5581 ttttgatctc aggtttgaac gtaaattgat agccaataac aggttttccc cgtccttttc
     5641 cgtatttctt tttgattgtt agtcctttga agattgcagt tagttcttga cgtataggtt
     5701 ttataactcg tttatctata tcaggttgct tataactttt aggaatatct aataattcaa
     5761 gaaagtcttc tttggagaaa tatgcgaaac ctttggttct gtattgcttt aacagacgaa
     5821 acatagtctt tgcatagcca ctttgtagct cgttgaattg ttgtaaagaa tagcgtaccc
     5881 actcgtctaa attatttaac aaaggcagtg ctttttcgta aattcgtata tctacgtaag
     5941 gattttctac gtccccgttg attttaaatt ctgtaaacat tacaaacata tcgtaagaaa
     6001 gcccagactc acttctacga ccaaagcgta aagataagat tttttcataa gttgctttta
     6061 aatcttctac aaatcgtaca tttgcagttg ctttgtagtt acttaaatct tttagttggt
     6121 caaacgtaaa acgaactgtc ttatcccctt tttcacgcat tctagacacg atgg
//
LOCUS       DADGHT010000126         6144 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.128, whole genome shotgun sequence.
ACCESSION   DADGHT010000126 DADGHT010000000
VERSION     DADGHT010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6144
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.128"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(137..1099)
                     /locus_tag="JX887_002571"
     CDS             complement(137..1099)
                     /locus_tag="JX887_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1258502.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1101..2540)
                     /locus_tag="JX887_002572"
     CDS             complement(1101..2540)
                     /locus_tag="JX887_002572"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HAX1258503.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2725..4671
                     /locus_tag="JX887_002573"
     CDS             2725..4671
                     /locus_tag="JX887_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HAX1258504.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            4935..5807
                     /locus_tag="JX887_002574"
     CDS             4935..5807
                     /locus_tag="JX887_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAX1258505.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1954 a         1049 c         1092 g         2049 t
ORIGIN      
        1 atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac aactcctttt
       61 tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt atagacatta
      121 aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt aaaatataat
      181 ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata agacttgcaa
      241 tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca atgaaagagg
      301 taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt tgatgagcaa
      361 ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct ggtttgtgat
      421 ttataatagt tgactttatt tccatttcac gacggatagt agacagatta ttaggaattt
      481 tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat tctgtgggag
      541 aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt ttttgtaaag
      601 tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa acattaggag
      661 ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca gcaattccaa
      721 gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt tcaatgtatt
      781 ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat ccatgtttaa
      841 ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta atattaggaa
      901 aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa ttatttggtt
      961 tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct gataaatatc
     1021 ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat tcagcgacat
     1081 cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt aggttcgcct
     1141 gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt aaacactttt
     1201 tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt agcagttgtt
     1261 tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata ttgaatgcct
     1321 gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa gctaagtcca
     1381 tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg aaaagttagt
     1441 tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga actagcacgt
     1501 aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat tgaaagttct
     1561 tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc gatatcaggt
     1621 agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc ttgagtcgca
     1681 tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag ttttactttt
     1741 tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc ataatttagc
     1801 tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc tacaaatact
     1861 agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag gttgccaact
     1921 tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa gcctgatttt
     1981 tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa catttgtgga
     2041 tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc acctttcgta
     2101 atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc ccaattttca
     2161 tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata tgcagaaccg
     2221 gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc tgttacatga
     2281 aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg agcagctcca
     2341 aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa accattagga
     2401 tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg tgatcgtttt
     2461 acattatcct taattttatc catctcatct ttagtccaat cagaataagc acgatatcgt
     2521 atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa ctagtatggt
     2581 aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat atgacaaacg
     2641 tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc gttttcacgt
     2701 aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga cgtaatacaa
     2761 gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct tcgtctcgta
     2821 ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga tgtgaaaagc
     2881 acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt taatttcgtt
     2941 tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga tttaaaacaa
     3001 attgctagta aagataaaaa attcaacccc attatggcat taattaaatt attatcagat
     3061 atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc attacaaaac
     3121 tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta tcctgcgatt
     3181 gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt cttaccaatt
     3241 ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg tgctgcaatt
     3301 ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa tatttttggt
     3361 tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc agctgtttgg
     3421 atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat tgactttaca
     3481 ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt tattggccct
     3541 gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata taacactact
     3601 ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat gactggttta
     3661 catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa tggtatcgga
     3721 catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg tgctgcaaca
     3781 tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc ctctgcgggt
     3841 gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt aaaataccgc
     3901 tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc aggattactt
     3961 aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc aattaatgca
     4021 acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc ttttgcaatt
     4081 acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga aattgctgaa
     4141 caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac tgatgttgaa
     4201 tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg taaagtgatt
     4261 agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa agggattgcc
     4321 attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca actcacgttt
     4381 gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct aattcatatt
     4441 ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac tactaatcaa
     4501 aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga gaaagaaggt
     4561 cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga agtaaatata
     4621 gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata aatatatttc
     4681 cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat caaatatttg
     4741 agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta ttagaatttt
     4801 aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca tgttactaaa
     4861 taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat tctaaaataa
     4921 agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa tttgtgtgtg
     4981 ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca acgacacctg
     5041 aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat ttagcaggga
     5101 ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact tatgggtaca
     5161 ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc atgaaaaaag
     5221 aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat ggtgagtatg
     5281 tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt acgggtgttg
     5341 gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca gaaatggggc
     5401 atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca tttcatggca
     5461 actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg aaaaaaggac
     5521 aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt gctcaatgtg
     5581 cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt ggtgtgatga
     5641 aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc aatgggtatg
     5701 tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac aacgctggaa
     5761 cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg aaaaaaggct
     5821 cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat aaccagttag
     5881 gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat gagataaatt
     5941 cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt gcaatagttt
     6001 tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat aggttctgtt
     6061 gcaaagtttt aaatctacta tcagataagg tagaataata gaaaaagata gcaggaggaa
     6121 tgacgatgag tcattttaaa ggaa
//
LOCUS       DADGHT010000127         6065 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.129, whole genome shotgun sequence.
ACCESSION   DADGHT010000127 DADGHT010000000
VERSION     DADGHT010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.129"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            832..1566
                     /locus_tag="JX887_002575"
     CDS             832..1566
                     /locus_tag="JX887_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1258506.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1582..2751
                     /locus_tag="JX887_002576"
     CDS             1582..2751
                     /locus_tag="JX887_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAX1258507.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2767..3762
                     /gene="lacD"
                     /locus_tag="JX887_002577"
     CDS             2767..3762
                     /gene="lacD"
                     /locus_tag="JX887_002577"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAX1258508.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3841..4767
                     /locus_tag="JX887_002578"
     CDS             3841..4767
                     /locus_tag="JX887_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HAX1258509.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4786..6036
                     /locus_tag="JX887_002579"
     CDS             4786..6036
                     /locus_tag="JX887_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAX1258510.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2026 a          997 c         1245 g         1797 t
ORIGIN      
        1 attggcgcag cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta
       61 actttaactg ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac
      121 aatcggaata gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt
      181 gccattccaa agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt
      241 gactaaacga agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat
      301 tcagataaac tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc
      361 ttaagagaga acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat
      421 ttattctcat agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga
      481 tttgaaacca aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca
      541 ctggtaagta gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta
      601 aaaaaagata ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa
      661 aagttggaaa attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat
      721 attaacaaga ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa
      781 ataccactac tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat
      841 acctttcaat caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa
      901 aacagtatgg tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc
      961 gttagtcgca cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat
     1021 cgacaacatg gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct
     1081 ggcgcatata gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata
     1141 ttggccttca agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta
     1201 ggtgagcctt tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc
     1261 gagaaatcct atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg
     1321 aaacctttat ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag
     1381 gaattttatg ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga
     1441 tcaccagtgc tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt
     1501 acattaagtg tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact
     1561 aactgaattg gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga
     1621 gcagaaaata ctacccgaga aattcgacaa caaccggaac tgtggcatga gacgtttgac
     1681 cgttatcaag aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct
     1741 ggagagcgac caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat
     1801 acactaattc cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt
     1861 ggttcgaccg atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc
     1921 ttggtctcat ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc
     1981 aatcagctgg tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg
     2041 gctacacaaa tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat
     2101 gacgctggtt ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt
     2161 tttgatcaag caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga
     2221 gaagaagtca tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc
     2281 atcatttact taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt
     2341 ctcgagttaa ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat
     2401 ggtcccaaat cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca
     2461 tatacgcaga aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa
     2521 cgcgttgttg gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt
     2581 gcagattcgt tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg
     2641 atcgcattac tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga
     2701 acagtcaatc gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg
     2761 tgaagcatgt tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca
     2821 gaaggcatta ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg
     2881 gctttaggga tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa
     2941 gaattgactc cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca
     3001 cagaagcgtg cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa
     3061 accgtacccg gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag
     3121 ttaggtgcgg atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc
     3181 aatcggcaaa agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg
     3241 ccattttatt tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc
     3301 tatgccaaag caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag
     3361 tataaagtag atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat
     3421 gcaacagggg agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc
     3481 gatgcaacag atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg
     3541 gagacattgc gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga
     3601 gcaacttgga aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa
     3661 tggctgacag aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact
     3721 gccatcccat ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt
     3781 agtgataaga gatatgtgtg attataattt atcattattg aaactgggag gatattttat
     3841 atgaataaaa gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa
     3901 ttaaagcagg caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt
     3961 agctgtcctt acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct
     4021 gatttaattt tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta
     4081 actctaaaag agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta
     4141 aatttagaac ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt
     4201 ggtagaatcg tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt
     4261 tgtttaactg gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca
     4321 ttatccaaat caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt
     4381 gatgaaccaa ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt
     4441 ttattagttc ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc
     4501 gttgattata taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta
     4561 acggctaatg gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta
     4621 gcatcaaaag catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt
     4681 cttccagaaa atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt
     4741 atgttaggaa aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt
     4801 caaaaaatag ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg
     4861 gctgcagtta tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg
     4921 atagaaggat ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca
     4981 tcagattcaa catttggtat tattggatta gctgttacct actctttggg acacaatcta
     5041 gcaaagactt atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt
     5101 ttacttacac ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt
     5161 acctcgggtc tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg
     5221 tttgtactta aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga
     5281 gctttcgttg ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta
     5341 atttgttata aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa
     5401 ccactatctt tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt
     5461 ttcttttgga tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta
     5521 ttattgcaaa actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac
     5581 attataactt atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt
     5641 gcacttgcca ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag
     5701 ttatcaatcg ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact
     5761 atattaaata taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt
     5821 acttattttt caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg
     5881 acaactccac cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg
     5941 attcaagtaa taacaattgc aataaatgtt ttgatatact atccattctt taaattagat
     6001 gataatgcca agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt
     6061 agtta
//
LOCUS       DADGHT010000128         6016 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.130, whole genome shotgun sequence.
ACCESSION   DADGHT010000128 DADGHT010000000
VERSION     DADGHT010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.130"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            5..1087
                     /locus_tag="JX887_002580"
     CDS             5..1087
                     /locus_tag="JX887_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017414133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1258511.1"
                     /translation="MNDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTDT
                     RVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINAE
                     FKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKIIS
                     LEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVKN
                     DGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKEDG
                     ELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISIT
                     MDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1294..2436)
                     /locus_tag="JX887_002581"
     CDS             complement(1294..2436)
                     /locus_tag="JX887_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1258512.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2441..2626)
                     /locus_tag="JX887_002582"
     CDS             complement(2441..2626)
                     /locus_tag="JX887_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAX1258513.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2980..3225)
                     /locus_tag="JX887_002583"
     CDS             complement(2980..3225)
                     /locus_tag="JX887_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1258514.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3219..3620)
                     /locus_tag="JX887_002584"
     CDS             complement(3219..3620)
                     /locus_tag="JX887_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1258515.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3807..5615)
                     /gene="uidA"
                     /locus_tag="JX887_002585"
     CDS             complement(3807..5615)
                     /gene="uidA"
                     /locus_tag="JX887_002585"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HAX1258516.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5638..>6016)
                     /locus_tag="JX887_002586"
     CDS             complement(5638..>6016)
                     /locus_tag="JX887_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011609746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAX1258517.1"
                     /translation="LSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRI
                     VWPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKL
                     MGLSEFKGVSPIDAYCGLKDTFI"
BASE COUNT         1945 a         1131 c          848 g         2092 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa tccatgtaaa catggtttat
     1141 tttttacact gttttcaaac aaacccttgc tatttcttcg gttcgtcctc gtccattttc
     1201 gataccgaca gctagcttat aacccaaggt atatcaacat aaaaaaataa aaataggcta
     1261 tgacagcagc gtgacagcaa aaaagatgga aagttaaata tcaaacctcg taatttcatt
     1321 tgcgagtgct tgatttgttt ctggatataa gtgtccatat ttgtccaaag tagttttaat
     1381 agaggcatga cctagacgct tagatattgc atagatattt ttattatgtt caattaaaaa
     1441 ggcaacatgc gagtgtctta atccatgcat atgaattggt tttactcctg caatttcagc
     1501 tagttttttt attctgctta aaatagttct tggagatggc ggtaatccat caaaagaaaa
     1561 aaccaattct atatttttcc caattgattg ttgagttttt ttccatgttt ttaaatcttc
     1621 aacggtttgt ctgtctaacg aaattatccg aatacttgat gtattttttg tttcagcaaa
     1681 ttcataatct tgtcttgtac ggatgtaaat tgacttattt acgctacatc tgccatttat
     1741 taagtcaaag tctttccatt gtaacgctaa gagctcctca ctccttacac ctgtaacaaa
     1801 aataaaacgc atcaaacgtt tataaaattc ttcataaaaa tccccgtgat aaacactatt
     1861 atatactttc ttaaattcat caactgtcca aaattctact tgaggacgct gagtttttat
     1921 tttacctata gtatctacag gattttcttc aataatttca agtacaattg cccttttaaa
     1981 aactactctc aacttattga atatctgttt aatataattt ggtgataatg gttgctcaat
     2041 gccctttttt acaacatgga ttttcgataa aaactgttga aattcctgta tatgaattgg
     2101 tcgaatcttt acaacctgca tttctccaaa aaaatccaat gcacgttgta aaatatgatc
     2161 tgttttcata tatgtttttt ctacagttcc caacttatac caaggaaaaa aatactctcg
     2221 ataaaaatca tgaaacgtta ttccttgcag ataaattcct tgtgaatcag aaaaactttg
     2281 ttttaactct tcgagtcccc ttctagcttc tccttgagtt ttgaagcctc ttctggtcac
     2341 ttgaattctt tttccaaagc gatcttgtcc taaagttgca gaaaaaaacc aagtgcctct
     2401 ttttctgtct ttataaacat tcgcaatttt cctcatttta ctattcctcc caagaaatat
     2461 ggagaacttc ttctaaaatt gaaataggaa ttctttttat ttttgaatta cgataaaaaa
     2521 agtatccttt ctcaactaaa agttctttac attccttgaa gattttatta gcatagtact
     2581 gagaaaaacc tagattaatc aaatcttttc gagtagctgt tttcattata gcaccttcct
     2641 tacttttttt catttatttc tatcagctgc ttttgtcaaa agcacatagg aatttcacct
     2701 ctccccaagt ttacggcgag ccttacggaa gtatcattat cccaacttta aatcatcgct
     2761 ttttattgac tataaaaatt attttagaat atttatcgct ccttctttac agcaagaaat
     2821 catggcgcaa ctaaaatatg ctccttaaag tgttaacgta ctgatagaat ctatttaatt
     2881 ttcaatgaac aataggtttt ctacctaaaa gaatctacta attccttaac tattagaaga
     2941 ttcttttaaa cagaaaaagt ggaaagggga tttttttaat tagttaattt taaattttaa
     3001 gatcgcttct attaatttaa tttctagctg acttatcata tattcatcta cataggtaac
     3061 gaattgacct acctcgttaa atccatttgt caaacataac ttagccatat aagaatgata
     3121 atgtttgagt atcatcttga tcgaaattgg atctccttct agagcagata agataatgga
     3181 tagtggaact aataggtact gccgcttttt agatttatct accataggtc ataccccatt
     3241 ttcaattgtt caactgcctt ctttcgttga taccagatac cacttgtgct catattgaga
     3301 attttaccga tttcagcatc attaaaacct gcaaaataat aaagtaggat aatctttctt
     3361 cttatctccg ataactgatc aattgctgct gataactttt gatctgaaat taatatttcc
     3421 attccaaata agaaatagac atcttgttca tcaaaatgag tttgggaata cctgccttca
     3481 tttgaatctg ccaatggttc ctcattatcc tttatgttag cgtttcgttt tcgaatagac
     3541 ttagcttcgt ttcgtaatac ttttttacag taggcatcaa attggtgttg tatagatatg
     3601 tcattgtaat gttgttgcat gataatatgc tcctttttcc ccctttccac taatacaaca
     3661 atcagaaagc cccttttttt cgaaaaaact agaaaaaaaa cataaaaata tttatcattc
     3721 tttaaacaga aaatctttct ataaaaaaca aaaaaaaacg attaggctag gctaatcgtt
     3781 ttttgaacat tcttaaaaaa tccaaattat tttttataac tgaaattggg tattgatgac
     3841 catcgtttct gtagatagta agcaatcatt ttaggttttc tatctctagt aaagattcct
     3901 ttcttatttc cttgcactct taaaatccct tgacttgttg caaaatctgc aaaattccac
     3961 acttgttcac caacaaaatt ttcacatgta tctattactt cgtgatttgc ttcgtaataa
     4021 gccacttgat actcttctgt aaacattgtt ggtactgtat catgaaatcc agctactgta
     4081 tctgctccat attctgtaaa cattattggc gtatcaggac atctttccat ccatccatct
     4141 agctcttttt tcaacagata ttttgcatgt gccagatccc ctcccgaaac ataccaacca
     4201 taataacgat ttaaacataa aacatcgaca atatctccta ccttacaaac atctggcgtt
     4261 gattttagat aagtaacgat tgttacaggt cttttctgcg gatcaagttc tttagttaat
     4321 tcaactaaag gttcaaaata ttctttagca ccttcggaat ccgaatctgg ttcatttgca
     4381 atagaccaca ttacaacact tgggtggttc ttgtcgcgtt ctatcaattc cttgatcacc
     4441 gttttatgag aattttctgt tcgtatctct ttccacgtat tatgtttttc cacattatca
     4501 tctaataaag tggccatgaa atttaaatgt aaccctactg caggtacttc atcaataact
     4561 acaatacctt ctcgatctgc taatcgcata atttcttctg agtaaggata atgtgatgtt
     4621 ctaaaagaat tagcacctat ccatttcatt aaattaaaat ctttaatatt tacagcctca
     4681 ttcaaaccac gtccattaac atacgaatcc tcatgcttac caaatccttt aaaataaaaa
     4741 ggtttattat taatcaaaaa tttgccattg gtaacctgaa cactgcgaat accaaattct
     4801 tctgtatagg tatcgatcac tttattatca tcaattaaac taattttcat actatataaa
     4861 taagcgtcta gaggttccca aaaaattgga ttcttaagct gaatcattcc tttctttcct
     4921 tcagcttcag ctacaagttg agcctcttcg tcatatatcg ctattaagat ttttccggtc
     4981 cattctgtat cgatattgaa ttctacactt gcatccaaat cagttattct tgtattaata
     5041 gtaatatcac ttatatagtc tttcggagtt gtatataact taacaggtct atgaatacct
     5101 gcataattga agaaatcaaa attaactaag ttttcctttt ttatatcccc attttcctgt
     5161 actgtttcct tcataatccc cacaggtaaa gtactatcgt caataatatt gtttacagca
     5221 actgtaattc gattattccc gtcttttaca aaccgattaa tttcagactc aaatggtgta
     5281 aacccacctt tgtgttgagt aataaacttt ccattcaaaa aaacttttgc ttcatgtgtt
     5341 gcagatccaa aacgaagaac taatctttct tctaataatc ttttaggaag agtcacttct
     5401 ttttcatacc acacccatcc aacatgattt ctaatgttct ctgtttcaaa taaatcatta
     5461 taagaagagg gaactgaaat cggataactc tctttttcat ttattggttc taaagcaagt
     5521 tcttcctgta agtcatcatt tgtatctaat ttaaatctcc agagaccgct taagtcaatt
     5581 acttgcctcg tctctgtcat aatgggatac aacatataaa ccactcctat ctaaatatta
     5641 aataaatgta tcctttaaac cacaataagc atctattgga cttactccct taaattcaga
     5701 aagacccatt agtttgtcca ccaatatttc taaagtttct tgttttccat cataagtatt
     5761 aatataagtc tttacttgag gtacatcagc caaatgaaac ggacactgta cagatacaaa
     5821 aattgttgga atttcatgaa tgtaaaacgg tatatccgga gttcctttac ttgctggcca
     5881 gacaattcgt tgaactgtgc ctggattaac attagctata ttaatgatca agtcatattt
     5941 tttagttaaa tttttaattg gtctcttagc agcatatatt ccagctatat ttttaatttt
     6001 ttcttcttgc gataat
//
LOCUS       DADGHT010000129         5883 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.131, whole genome shotgun sequence.
ACCESSION   DADGHT010000129 DADGHT010000000
VERSION     DADGHT010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.131"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(34..1128)
                     /locus_tag="JX887_002587"
     CDS             complement(34..1128)
                     /locus_tag="JX887_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAX1258518.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            1317..2078
                     /locus_tag="JX887_002588"
     CDS             1317..2078
                     /locus_tag="JX887_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAX1258519.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(2193..2633)
                     /gene="fabZ"
                     /locus_tag="JX887_002589"
     CDS             complement(2193..2633)
                     /gene="fabZ"
                     /locus_tag="JX887_002589"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAX1258520.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            2853..3608
                     /gene="fabI"
                     /locus_tag="JX887_002590"
     CDS             2853..3608
                     /gene="fabI"
                     /locus_tag="JX887_002590"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAX1258521.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(3718..4731)
                     /locus_tag="JX887_002591"
     CDS             complement(3718..4731)
                     /locus_tag="JX887_002591"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAX1258522.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            4896..5816
                     /locus_tag="JX887_002592"
     CDS             4896..5816
                     /locus_tag="JX887_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAX1258523.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
BASE COUNT         1781 a         1175 c         1059 g         1868 t
ORIGIN      
        1 ttctagcgga ttatttctgc aataactaat tatctatttt ttattttcaa ttaatttaaa
       61 gcttgaccat ggtttcaaaa agtcaaggag gaataattcg tcatcggaga ttcttcctac
      121 aacattgaca cgtccgtcgt ttttcatatc cttcaaggcg atttgtgttt ctcctttgta
      181 ttgaccgtac ccttcattgt caatcagtac atccccatga tgcatatctc gcgtattatg
      241 aggcgggaaa tctttatctt tgtagtatac acgagtcatc gttgaacgaa ggatatattc
      301 tgagcgatcc cctcgataac tatgaaggtt atcaaacaag cagattcgtt cgttttctgt
      361 aataccttct tccgtatcta ctttcaatgt tggataatcc gcgttaaatg cttctgccat
      421 ttctttcaat tcttcttcac ttgcgtacgc atttccaata gaaatatcat caatcaatcc
      481 tgtaaggatt aaatgcttca cttgtgtcgc aatttcaaga tctcggtggt cttccagcgt
      541 gcacaagcca tcttgcgtag gccaagggcc aaactcagca gattgcgaat tgacgaatgc
      601 catcgtattc aaattatatt ttctgaattt ttctgaacaa aaaacaaagt gttcgtatcc
      661 taaaccagag tatcgatgag gataaaaatt atgagaacct aataaattat ccgtgtttgg
      721 cgaataactc atgatgttgt caacgtaatt cgtgcccgaa ctcatattga tctcgatttt
      781 gataccaaaa ggattgcgcg tcatttttgc ttcttctgct cctgtgaatc cgatatctaa
      841 gcggaccccg taggcaccca tcttatggaa aaaagataag tcatcgtaag aaatctccaa
      901 ctgttcaaat aacgctggat tgatatcaac cattacttcc atgcctaggc tattcgcgta
      961 atcaactact tctttaaatt ctgaaagaac tttttcttta tcatcattga tctgcagcaa
     1021 actggtaaaa acccgtttat acccatactt atgagctaaa tccaagtacg ctttgtcctt
     1081 ttcaaatgtt gaccgttctg gataaatcga gattcctaat tttcccatat taccatttcc
     1141 tcctgcatct tttcgttttt gtatccactt acattatagc aaacacaaag taaatggtct
     1201 acaccttttc tttttctttt aaaataaatg ataaattcca ataatttaag taggtatttt
     1261 ccctctattt tgttatcatt aaagataaca aaatagtaaa ttggaaagga acagttatga
     1321 agaaaaataa agttatttta agtattagtt tagcagcagc attgctgttt gctgctggtt
     1381 gttctgcaaa caacacgact tcttctagtt cgtctacaga aagttcaaaa agtacatcta
     1441 ctgcggaaag cacgactgcc agtagcgtcg atttgaacgc attggaatta ccacaattga
     1501 cgaaagatgt cgccgaaaat gaagatctgg tcgaaatggt gacgaataaa ggcacaatca
     1561 aaatcaaatt atttcccgaa cacgcaccaa aagcggttga aaactttatg acacatgcaa
     1621 aagacggtta ctacaacgga ctgactttcc atcgcgtcat caaagatttc atgatccaag
     1681 gtggcgatcc taaaggcgat ggcactggag gggaaagcat ttggggagaa ggatttgaaa
     1741 cagagatcaa caaccacctt tataatataa gaggtgcgtt atctatggct cgctcacaag
     1801 atcctaacag taacggcagc cagttcttta tcgttcaaaa tacagatgat atgcatgatg
     1861 gtcttttaaa agacgactat cctcaagcaa tcatcgacgc ttataaaaac ggcggttatc
     1921 cttcactaga tggccattat actgtcttcg gccaagtgat tgaaggaatg gatgtcgtgg
     1981 atgctattgc aaatatcgaa acagatagtt cagacaaacc aaaagaagaa gtaaaaatcg
     2041 ataaaatcaa tatactgcaa gaagcaaaac aaaaataaaa aaataacgtc tgaatcctgc
     2101 atagatgaca acgtatgcta ggattcaggc gtcttctttt tacataaaaa gcaagtaagc
     2161 ttccttttgt tttgctatat caggttttat agtcaagcat tttggttgac gatgaacgtg
     2221 aactcgcact cacagacttt tttatcatct acatatgctg cagataacgc tgtaccgact
     2281 gatcccttca ttttggtgat ttcaaaatga catttcagca catctcctgg aacaactttt
     2341 tgacggaatt tggccttatt gatcccaccg atataagctc tttttcctag aaactcttct
     2401 gattttagga taagtatcga acctgcttgt gccagtgttt ctagaatcaa cgcacccggc
     2461 atcactggat tgtcaggaaa gtgaccttgg aaaaaatctt cattgattgt tacatttttt
     2521 gtcgcaacga tcttttttcc tggttctaaa gtatctacat aatcaatata acaaatagga
     2581 taacgattag gaatcaattc cattacttca gtagcagata atacgtaaga cataattaaa
     2641 ctccttcttt caggcaattg ccattttcat tactttgact atcaaagtat catattccta
     2701 aatatttagc aatctttttt taatttaaga aaaaatagtt tgacaatcaa aacattttga
     2761 ctaataatta agaaatcaag aagttatttt agctattatt ctctattttt ttacgactat
     2821 caaattttta tcagaaacaa aggagagtca ttatgtcatt tctagaagga aaaaaaatcg
     2881 tcattatggg cgtcgctaac aaaaaaagca ttgcttgggg ttgtgctgaa gcaatgttga
     2941 aacaaggggc agaaattatc tatacttacc aaaatgaacg aatgaaaaaa tcattagtca
     3001 aattggtcgg cgaagaagca ttcactgtag aatgtgatgt ttctagcgac gaaagcatcg
     3061 aaaaagcaat gaatgccatc ggtgaatatg ctggggagat ccacggcctt gtccatgcag
     3121 ttgcttacgc caacaaagaa gaattgtccg gaaatgtgtc tgatatttcc agagacggct
     3181 atcaattagc tcaagatatc agcagctact ctttaattgc tgtatcaaaa tacgcacaac
     3241 cgtttcttgc accaaacagc gggatcgtta gcatgactta tctaggttca gaacgcgcaa
     3301 tcccgaatta taacatgatg ggtattgcga aagcttctct tgaagctgct atccgttatt
     3361 tggcagctga gttctcgcct aaaggaattc gggtcaatgg aatctcagct ggggcaatca
     3421 aaacattagc tgtcacaggt gttaaagact atcaaaaact gatccagtta tctgaatctc
     3481 gtacgcctga tcagcaaggt gtgacgatcg aagaagtcgg taatgcttgt gctttcttaa
     3541 tcagcccact ttccagcgga atcatcggtg atattatcta cgttgacaaa ggtgtccatc
     3601 tttcataaac ttttgttgca ttctttaaag taaaacatat aaaaatcagg aaaaaacttt
     3661 ttaaagtctc ttcctgattt tttcttttta cgtttttttc aactcattac tttgaaatta
     3721 ttccacgact tcaatccagc cttctggtgc ttctatgtct ccaaattgaa tacctgtcaa
     3781 ttcatcatac aaccgttttg ttactggtcc tacttccgtt tcactataaa atacatgaag
     3841 attgttattg tgataaatcc caccgattgg agaaataaca gccgctgtac cacatgcacc
     3901 agcttctgca aattgatcta gatcatcaat gaaaatatct ccttcaattg cttgcagtcc
     3961 tagtcgttct tcagctaact gcaacaagga atatttcgtg atacttggta agatagaggg
     4021 cgattgcgga gtgatgaatt ttccgtcttt tgtaattcca aagaaatttg ctgcacctac
     4081 ttcttcgatt ttcgtatgtg tggctggatc aagataaaca caatctgagt aatccagttc
     4141 ttttgcttct gttcctggaa gtaaactcgc tgcgtaattt ccgccgactt ttgctgcacc
     4201 agtcccctta ggagcagcac gatcgtaatc agatacaata aaattcgttg gttttagtcc
     4261 acctttgaaa tacgctccta ctggcgtaca gaagacgaca aataaatatt ctggagctgg
     4321 atggacacca atgttttcac cgaccccaat cagtaaaggg cgcaagtata atgtagcgcc
     4381 tgttccatag ggcggcacaa aatcttcatt tgcttttacc acttgcttga cagcatcaac
     4441 gaacatcttt tcagggacca ttggcatcag caatcgtcta gcactttgat tcatccgtcg
     4501 actattttgt tcaggtcgaa agagattgac cttgccgtct tttcgacgat aagcttttag
     4561 accttcaaaa cattgctgac cataatgaag cgctggagag ccttcatgaa tcgtcaggta
     4621 attatcttct gtcaattctc cttcttccca ttgtccgtct ttccatttgg caataaaacg
     4681 ccaaggagtt ttgatataag aaaaacctag attgttccaa tcgatttgca tatacttacc
     4741 accttcgtta ttttctccac attttatcat tatccatatt atttgtcatt ttattttcag
     4801 cttttttcct tcattatagt tatttttgct atttcctttt ttgaaaactt cttggtacaa
     4861 tacagaaaga atcaaatttt agaaaagagg attttatgtt ttcattatta gcaactgccg
     4921 gtacgacaga ctcttctggc gagacattga cagatcaagc tgtcagcaaa gtaaatgcgt
     4981 ttcagcggtt ttgggacggg attgattggg acgccatttt ggctgccttt atccaaaaaa
     5041 gtttatatct gatttttttg atcgtccttt tttggattct tcaccgtgtg ggaaaatatc
     5101 tgattgataa gtcttttaat cagtattcta aaaaagccat tctaaacgag agccgcttaa
     5161 agactttaca tagtctttta aatactattt ttcattatac ccttggtttc ttttttatct
     5221 atgcaatttt atctgctatc ggtgtgccga tcggatcact tttggctggt gccggaattg
     5281 caggtgtggc aatcggtctt ggtgcccaag ggttcatgag tgatgttatt accggatttt
     5341 ttattatcat ggaacaacag atggatgttg gggactacat caagctagca aacttaacga
     5401 ttgaaggaac cgtcgtatct gttggtatcc gtacccttca gctgaaagca acggatggta
     5461 ctgtccattt catcccgaat cgaaacatca ccacgatcag caatctctct cgtgcaaata
     5521 tgcaagtact tttagatatt cggattgttc ctgaagaagg atatgacaaa atctatgaga
     5581 tcattgatcg agtaaatcgt acattagctg aaaaatacca agaagagctc caaactgaac
     5641 cttctatctt tggattagtg gatcttggaa acagcaattt tgcgattcgt acggtctgct
     5701 acgcattgaa cggaaaacaa tatgccttaa aagaagagtt cttgagctcc tatgtcaaag
     5761 aattgacagc ttctggtttc acgattccga acagtccaat tgctgtcgga aaataatttg
     5821 gacaaacgat gcaacgaatc tcactaaaaa gagcgtggga caaaagtaaa gaacactttt
     5881 gtc
//
LOCUS       DADGHT010000130         5814 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.132, whole genome shotgun sequence.
ACCESSION   DADGHT010000130 DADGHT010000000
VERSION     DADGHT010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5814
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.132"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(13..765)
                     /locus_tag="JX887_002593"
     CDS             complement(13..765)
                     /locus_tag="JX887_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1258524.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(1129..3795)
                     /locus_tag="JX887_002594"
     CDS             complement(1129..3795)
                     /locus_tag="JX887_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAX1258525.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            4136..5587
                     /gene="cls"
                     /locus_tag="JX887_002595"
     CDS             4136..5587
                     /gene="cls"
                     /locus_tag="JX887_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAX1258526.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
BASE COUNT         1678 a         1230 c         1021 g         1885 t
ORIGIN      
        1 aaaaagaacc cttcacgagt cgtgaaaggt tcttttttta tctgcggacc aaaggagcag
       61 tctataggtc agcttagtcg tactaaggat ttctcgtttt tcactgaata gtttgcgaat
      121 gtacctggtc acaacaggat cttttgcgta cgcgtcatag tatagcttca tcaattcttc
      181 agtaattgat tcctgtgtaa aataagtaaa atcttttttc ttcactttga atccttcatc
      241 aattaagtat gtttcaaatt gatccattac aactggcgat gtattaggat cttcttctat
      301 cattcctagt tgcttttcga taggataaaa aacatcatcg attgattcca ctactctgat
      361 tatcacgcac catttgcttg actttttcat caatttttct aattgaataa gatgtaccaa
      421 tgctggattt gctgctgtaa aaaccatttc atatgtctca tttgattgga taaattcttc
      481 taacgactgt ttgataaagg aaacatttgg caactcattt ttttctgctt ctttttttgc
      541 attttctagc attcctgaag aaaaatcgat caaatcatag cgattaattt cttttgctaa
      601 ggaaagaaat ctgccagatc ctccagcaac gtctgctgct gtttcagcag gcaggacttt
      661 ctccgttttc agataatttt ttacatcttc agcaatagtt acttgcgatt cttgctggat
      721 ttcataatat tcttcagcaa attcatccca ttctttttca ttcatttgat ttcctctaat
      781 tttttgttat atgttttcac ttttcggaat aaatcattct cctcttttat ctattctatc
      841 tcttttgatg aataataaaa tgattggctt tccgtctatc ataaataaaa aaagggactg
      901 tgaccaaagt cgtgtcaaag tccctctttc cgaataaaca gtgtccaatc agatgaccct
      961 cagtattagc tcaaaatgct gattttacaa cttcttcctt aaacggtgtt ctcctgccaa
     1021 ctcttcggtc acaagtcaca atattcaaca aacatgagaa gctgtttgtt gaaattgcac
     1081 cttgtgactc agaattaaac ggcaggctca caacctcgtt gattcgtttt atttatttcc
     1141 ttgtactcgt acaatgatca atttagtgat ttccatcaaa acaattgtca caagtgcgat
     1201 tcccatacat gtaaagactt ctgtcaatcc aaatgctgat gggatagaga agacttcttt
     1261 cagtcctggg atcattgtta agcagtaaag cgcgctacat acaactacag ctagtaagac
     1321 acttctgtta gagaagaacc ctgcttggat agctgtttgt gtgtttgaac gtgctgggaa
     1381 tgtttgcaat gtccgacacc aaatcaatgt tgaaaatgac atggctacac cgaattcagg
     1441 tgaatgctgc atgccaagcc attgagcaaa gataacagca atcccaatca gcacaccacg
     1501 atacgttaca gaaatcaatg ttttgtccgt aaagattcct gaatttggat ctcttggcgg
     1561 gcggttcatc gtagcaggtt cagctttttc tgtacctaat gcaattgctg gcagtgaatc
     1621 attgactaaa ttgatgaaca acagttgtaa tgctgtaaat ggattggacc agtcagcaac
     1681 taaggcaaag atgatcgcaa tgatcgcacc taaatttcct gcaaatagat aagaaatagc
     1741 tttcttgata ttatcaaaca cattacgtcc tacttctact gcgctgacaa tagaagcaaa
     1801 gttatcatcc gtcaatacca tcgctgctgc atcttttgcc acatctgtac ccgttcccat
     1861 agcaattccg atgtctgctt gtttcaatgc tggtgcgtca tttacaccat cacctgtcat
     1921 agctgagata tgacctttat tttgccaagc acgaacgata cgaattttat tctcaggtga
     1981 aacacgtgca taaacagtga ctttttctaa aacttcgttt agttgatctt ctgtcaattc
     2041 atctagttcc gtcccggtca aagccaggtt tccttcttca aaaatcccga tttgttttgc
     2101 gatagcaaca gctgttgttt tgtggtcacc agtaatcatg attgttttga ttcctgcact
     2161 tcttgcttct gttaccgcct gagtcacttc agcacgtgga ggatcgatca tagcaagcaa
     2221 accaacaagg atcaaatcgt cttcatcttc aaatgataaa tcaaaattat caagtggacg
     2281 gtaagcaaaa gctagtacac gtaatgcgcg tgttgaaaaa gcttcatttt gctcttggaa
     2341 ttttttcatc aattcatccg tcatcggaac gacttcacca tttagcaata cttttttact
     2401 gcgttggaag acgatatctg gtccgccttt aacaaacaag taatttttgt tatcaattgt
     2461 gtgtccagta gacattaatt ttcgatctga gtcaaaagga agttctgctt gtcttgggta
     2521 gttgtttcgg atttcctgat aaggctggtt taatttttca ctaaagtcga taaacgctac
     2581 ttccgtaggg tcgcccaatt tagtaccgtc ttcactgatc gatgcatcat tcgctaaaac
     2641 actgatttcg atcaagcgac gttcgtcagc tgtccatttt gaagggtcat ttgtgaaatc
     2701 cccagtatcg ccattaccta aaaagtagtc aacaactgtc attttgtttt gtgtcaatgt
     2761 accagtctta tctgtacaga tgatacttgt cgaaccaagt gtttcaactg ctggaagctt
     2821 ccgaataatg gcatgacgtt ttgccatttt attcgttccc aaagataaca cgattgttac
     2881 gatagactgt aatgcttctg gaatagcagc tacggctacg gctacggcaa acatcactgc
     2941 gctgacgata tctgcagtca tatctcctgt accttctcca agataaatac gaaacagttg
     3001 gatacctaaa atcaataaag acaatgccaa aatagccaaa cttagttttt tactgaattt
     3061 atccagacct cgttgtaacg gagtgacttg ctcagttgtt gattccaaaa ggccagcaac
     3121 ttgtccgatc tccgtattat tcccagttga agtcactaag aatttaccgc gtccgtaagt
     3181 tacgatcgtt ccactgaata ccatatttgt acgatctccg attggtaccg tacttgtgat
     3241 atccgttact tctttttctg cagaagtcga ctctcctgtc agcatacctt catctacttt
     3301 taatgatccc gcatctagta aacgtccatc agcaggtaca taatcgcctg cgtctaacaa
     3361 cacgatatct cctaccacaa gttcgtttgc cggaatcgtt ttttccttac catcacgaat
     3421 cactcgagca tcgggcgctg aaaggttttt caacgcttct aaagaacctt ctgctttttt
     3481 tgtttggaca acactgatta tagaattcaa catcaatact gcaaaaataa ctaagaattc
     3541 gatgtagtca cccatgacca tctgaatcag tgcgacaatc agcaatacga taaccattgc
     3601 atctttgaaa gtttctaaga acaatttcca agttggcttc ttcggctttt cttttagctg
     3661 gttcaagcca tctctttcta atttttcctt cgcttgcgtg gtgctcaatc catcggttga
     3721 gctctgcgtt tgctgcatca acgagtcgat cgtttcttta tagaccgctt gttgtgcttg
     3781 ttccttgttt tccaaatttc atcccccatt ttttgatctt ggccctagtc ctgtctgaaa
     3841 aaaaagagac ctaagacaaa tacgcatttg tcttaggtct caccatttca tacaatacca
     3901 gaaaaccatt tggttaactt actgttgata ttatcgcaac aaacgttgcc ggttactccc
     3961 ctaaggagat attcaactgt actaatatcc taccttatta acctacaaaa agcaactact
     4021 ttagcccgat ttacctacat tttcatgaaa ggagtgaaaa gtatattcac cttggtaggc
     4081 ttctttcttc tatcatgcta tactaatgtt attgtatgta aggaggaaca tttttgtggt
     4141 atctagtatt ataaccgccc tttatctatt aaatgcactt attgctttgg tggctatttt
     4201 gatcaaaccc cgagatgtag cagccatttg ggcatggctc ttagtattgt ttgcccttcc
     4261 tggggtgggc tttgtattat atttattttt cggacgtgga ttaacggata agaaaaaatt
     4321 ctatctccga caaagtgact tgaaagaatt agaaaacttt cagtctttta gaggagatac
     4381 cattgaacat tacgatcctg acatgggcga taaagacaaa cagcaatttg ttgacttctt
     4441 ctcttcatta aatcgtatgc cgctgacaag aatgaattct gtcactcttc tcacagacgg
     4501 acaagagaaa ttggattcac tgcttcaaga tctaaaaaaa gccaaacatt cgatccatat
     4561 cgaatattac gcatttgtga cagataatat cggccagcaa gtcttacatg ttttagaaga
     4621 aaaagccgca gaaggcgtgg aagttcgaat attatatgat gcatttggct ctcatggcac
     4681 aaaagcaaaa gatttcaatc gtctaatcaa aaatggtgga catgtccata catttgttac
     4741 ctcacaaagg gcattacttc gtttccgatt gaattaccat gatcaccgaa aaatcgttgt
     4801 gatcgatgga aagattagtt ataccggtgg tttcaatatt gccaatcaat atgtaaatac
     4861 aacaaaaaaa ttcggctatt ggcgcgatac gcatatacgg attttcggtg ccgcttcttc
     4921 tttgctccag cttcgcttct taacagactg gaacgtctcg gtacctgaag aaaaaaaggt
     4981 cggctatcat ttgaattatt tctttaaaaa agcagatcga gatgaatcta agcttgctga
     5041 tacatccatc cagcttgttt caagcggacc gaataacgaa agggaacaaa tcaagctttc
     5101 atttatcaaa ttgattactt ctgctaaaaa acgtgtttgg atacagacac cttaccttgt
     5161 tcctgatgaa agtgtcattg ctgctttaaa aatcgcaact gcctctggtg tagatgtgaa
     5221 aatcatgatt cccaacaaac cggatcatcc ttttatttat cgagcaacac aatattatgc
     5281 tcggcagctg atcaaggaaa atgtacaaat ccttgtctat gagaacggct tcctccatgc
     5341 aaaaacattg ataatggatg atgaaatctg catggtaggt tcagcaaatc aagatattcg
     5401 tagctaccga ttgaattttg aaacaagtgc tgtcatttac gatcctgagt ttttagaaga
     5461 acttgctact cagttcaaag aagatgagac acattgttca tccatgacaa ctgaaacagt
     5521 caaggaaatg tctaactggc tattattcaa gcaacaaatt tctcgattat tttctccaat
     5581 cctataattt ttttattcaa gtagagaaaa atatactaag attaaaggga ctgtgacaaa
     5641 aatcttgtca cagtcccttc ttccgaacaa acggtgttct cctgccaact cctcggtcac
     5701 aagtcacaat attcaacaaa catgagaagc tgttttttga acttgttcct tgtgactcgg
     5761 agctggacgg caggctcacg acctctttct taaacggtgt tcaaaagctt gcat
//
LOCUS       DADGHT010000131         5808 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.133, whole genome shotgun sequence.
ACCESSION   DADGHT010000131 DADGHT010000000
VERSION     DADGHT010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.133"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(49..2220)
                     /gene="copB"
                     /locus_tag="JX887_002596"
     CDS             complement(49..2220)
                     /gene="copB"
                     /locus_tag="JX887_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAX1258527.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(2240..4426)
                     /locus_tag="JX887_002597"
     CDS             complement(2240..4426)
                     /locus_tag="JX887_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAX1258528.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(4426..4635)
                     /gene="copZ"
                     /locus_tag="JX887_002598"
     CDS             complement(4426..4635)
                     /gene="copZ"
                     /locus_tag="JX887_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAX1258529.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(4648..5088)
                     /locus_tag="JX887_002599"
     CDS             complement(4648..5088)
                     /locus_tag="JX887_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAX1258530.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(5162..5701)
                     /locus_tag="JX887_002600"
     CDS             complement(5162..5701)
                     /locus_tag="JX887_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1258531.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         1503 a         1305 c         1015 g         1985 t
ORIGIN      
        1 tcgaaaaaaa ggttgtgaca cgttttttgt cacaaccttt tttcattatt atctgatttt
       61 caatgtcaaa gcatttagag ctacaactac cgtacttaac gacatcaaga cagcaccaac
      121 tgctggactt aatatgatac caattggcgc aagaattccg gctgctagcg gaattgcaag
      181 aatattgtaa cctgcccccc accagaggtt ctggatcatt ttctttcgcg tttgcttggc
      241 tagatcaaga aaatgcaaaa tatcttttgg atcgctgttt gtcaatacga catccgcaga
      301 atcgattgcg atatctgtcc ctgcaccgat tgccatcccg attgaagcac gggctaaact
      361 tggcgcatca ttgatcccat cacccaccat gattactttt ttcccttggt caaggtattt
      421 ctggacaaca gcttctttat catctggtaa taaaccgcca taatattctt cgatccctaa
      481 ataatctgct actgcttggg cagcgttttt attgtcacca gtaagcatga caggagtgat
      541 ttttctttct ttcaatgttc ggataaattc ttttgcttct gtttttacta cgtcacctaa
      601 agcaacgatt gcagctagat gattttctaa aatcaggaag ctgatggtat ttccttgttc
      661 ttggtaaggt ttcaataatg cttgttctac gtttaatccg agacgctcaa cttctttttc
      721 attaactatt ttcacttgtt gttttttgac tgttgcctct agcccgactc ctgaaagatt
      781 ttttagattt tcagcttgat aaggcttgat ttcatgttct ttcaaataat tcataatgcc
      841 aacagccaat ggatgattgg cattcgcttc caaggctcct agatattgaa ggatttcatt
      901 tttattgaac gcatcatcaa gtacttcgac acccgttaca gtaaattttc cttctgttag
      961 tgttcctgtt ttgtccagca tgatcacatc tagatcattg gcttgctcca gtgcattgcg
     1021 gtttttcaaa agtaatccgt ttttagctgc tattgatgtg gaacgagcaa caactaatgg
     1081 gatagctaaa cctagagcat gaggacaggc gatgataaag actgttacca tacgttctaa
     1141 tgcattagga agatctgtca agaacaacca ggcgatgaat gccaggatac ccacaattaa
     1201 tgcgacataa aacagccatt ttgccacttt gtcagataat gactctagct tggatttttc
     1261 tccttgtgct tttcgcacca tttccataac cttcgctaga taaccatttt caccagttcc
     1321 agttacttcg atttcgatcg ttccatcccc attgatagaa ccgccaatca ctttgtcatt
     1381 ggcttgtttt ttgattcctc ttgattcgcc agtcacagct gattcgtcaa caattgtttc
     1441 acctttcaag attacaccat ctgttggcat tttatcacca gaccggacga tcaaacgatc
     1501 accttcgttt acttctttca atgaaactgt ctcttctttt ccatctttcg tcaagcgttt
     1561 cactgattct ggcagtaatt ctgctagttt ttgtaaagca ttgctggcat tcgacacagc
     1621 attcatttca atccagtgac ctagtagcat aataacgatc aaagtagcca attcccagaa
     1681 gaaatccatg acgtgtgtat gtggattgag cagatttgcg ataaacgaat agacactata
     1741 aatatatgca actgtaatcc ccatcgcgat cagtgtcatc atagcaggac ttttttgttt
     1801 caattccatc ttagctccac ttaaaaatgg ctgaccgcca tagataaata gtatagttgc
     1861 taagatcaat acgagccaat cagaaccagg aaacgttact tgaaatggaa attccattcc
     1921 catcattggt gaaaaaagaa tgattgggat agctaggata agcgatagcc aaaatttttg
     1981 tttgaaattc cccatgtgca tggaatgatc catgccgccg tgttcgtgat ccatgtgcat
     2041 cgaatggtcc atttgtttgc tgtttgctat atctccatgg ttatgtccca tgtgcatgga
     2101 atgatccatc tgactatggt catgtttcat ctccatctgt ttttcatgag attctgtact
     2161 ttctttgttt actacttctt ttttatgctc atgttttttc tccatatcgt tcccattcat
     2221 ttttactcca tcccttctct tactttttca tgtgtcgatt taagcacagg gagttcaaca
     2281 atacactgac ggaactaaac gccatcgctc ctcctgcaat gattggattc aaaaagccta
     2341 gtgcggcaaa aggaatacca atcgtattat agacaaaagc ccagaaaaga ttttgtttga
     2401 tttttctcaa tgtcaaccta gacaactcga ttgtttgtgc aatggatgcc aaactgctat
     2461 tcatcagcgt cacatcggct gtttccatcg caatgtccgt tccacttccc attgccatac
     2521 cgacatcagc taatgctaag gccggtgcat cattgattcc atcgcctgcc ataccgactt
     2581 ttttgccatc tttctgaagt ttttctacgt aggctgcttt atcctctgga agtacttcag
     2641 caaagatatg ctttggatca ataccaactt gtttaccaat cgtttcggct gccagtttgt
     2701 tgtctcctgt cagcataaaa acatctaatc ctttattctg gagctgcttg attgcttgtt
     2761 tgacttctag tttgatttga tcagccacgg caatcaaccc gatcacttgc ttttcatcag
     2821 ctaaaaacat gactgttttt ccctgctgtt ctaattctaa cgcgtgttct tggtattcat
     2881 caaatgatag gttcaattca attaatcgtt tacgtgtacc cgcaaaatag cgtactccgt
     2941 taatcgtacc gctgattcca gcacctgggt gggctgtaaa atcaatcata tcgtatgttg
     3001 ctgcttcttg cagttttccg tattccacga ttgctttacc tagtggatgt tcagaagctt
     3061 gttctaaagt ataaaaaata gataggactt ctttagaacc gactagatct gtaactttgg
     3121 gctttccttc tgtaatcgtt ccagttttat ccaaaacaat gctgtctaag tgagcagctg
     3181 cttctaatgc ttctccgcct ttaattaaaa ttccatttcg tgcaccaaca cccgttccta
     3241 ccataatagc tgttggagtc gctaaaccta atgcacatgg acacgcaatg actaatacag
     3301 agacactatg gatcaatgcg agttgccaat caccagtgat caaacctgta gctatgagcg
     3361 tgataaacgc gatgactaat acgatcggaa caaaaatccc tgagatccga tctgcgattt
     3421 tttggattgg ggctttgctc ccttgagcat cttccaccat ttgaatgatt tgcgctaata
     3481 ctgtctgctt gccgacttgt gtaacttcca tgtgaagtag accattcgta ttgattgtcc
     3541 cgccaaagag cgtgtcatcc ggattctttt ctacaggaag attttcacca gtaagcatac
     3601 tttcatctat cgcactgctt cctgaaataa ttcgaccatc tgctggaatc tgctcaccag
     3661 gacggatgac tagttgatca ccaacgacta cttcttcaat cgctaacgtt tcttctttcc
     3721 cgtttcttat cacttgggcg gtttttgttt gaagagacat caattgtttg attgcattac
     3781 ctgttttcgt ttttgctgta tgttccaaat atttgccgag caaaatcagc gtgatgatca
     3841 tactgctgct ttcaaaataa agatcttggg ggtgtccacg gaaaaatccg ttgtaaatgc
     3901 tcaatgcaaa ggcagccgat gttccaattg ctaccaatac atccatattt ggtgctttcg
     3961 tcttgattgc atggtacgca cctttataaa aacgagcacc gacataaaat tggacaggag
     4021 cagacagcac taactggacg attggaaaat gaaaaaagtg aacaatcgcc gcatggcttc
     4081 ctaacatcat agcaatcatt gacaacatca acggcaaagt caaaaccgta ctcaatataa
     4141 gatcgaatag catttttttc aaatacgctt gcttttcttc tgcaattttt tgtttgtggg
     4201 cttcatcgta caaaattgca ccatagccga tgttttctac gctttggatt aatttttcag
     4261 tggtcgtccc ttcatatttg acacttgctt tttcagtggc caagttgact gtggcattga
     4321 ccacaccagg ttgtccgttc agctcttttt cgatcctagc agaacaattt gcacaagtca
     4381 tacctgtaat gacgaacgta tccattttgg tttctgctgt tgccatcaaa tcacctctgc
     4441 tttataaccc aatccattga ttgcttgaca aatcttttcg gattgaactt ttgtttcatc
     4501 aaacttgacc gtaccgtttg cttttttcaa atttactttc actttttgca cgccgtcaag
     4561 tgcgcttact gtttcttcta ctcttgctgc acaatgattg cagctcatac cttcgattga
     4621 aaattgttgt ttcatttttt cttcctccta ttgatgttgt ttacattcac attgacctgg
     4681 gatacagtta cattcgatcg tatctactgg ttgcttttgt tccagttgtt tcaaaatctc
     4741 attgatatct tcttgagtca aagtggcttc ttctactaga tccgcaatcg tctctccaat
     4801 cctttttgca cagatatggg aaaaaagatt ttccgtcgca ctgcgaactg tttccatctc
     4861 cgagacagct ggataataaa tgaatttttt tccttcttgt tctgtccaga tcacttcttt
     4921 ttttaccaaa cgacccagca aagttttgat cgttgctggt ttccaatcca tcgaatcagc
     4981 taagatctgc gtgatttctt gggctgtcgt ctgtccaagt gtccaaataa cacgcatgat
     5041 ctcccactct gaatcactga tctttactgg cgttttgact ttttccattt atttcacacc
     5101 tttcgtttac aaatgtaatc attatcttat gaatacagat tacacttgta aacaaaaact
     5161 gtcaattatt tttgctctct attttcaatt tagttaaaaa ttcttgtttc tctcgtcttg
     5221 ttttaaggat gatcagttta tttcttgcat tagctacttg gatcagctgc tgtattttcg
     5281 gttcattgtt ttcttcaaaa tgccagataa aagataaaaa ttctaagtat tccctgttta
     5341 gtttctccga aaatgattca ggcatatctg gccgagattt tttgtttatc tttcttttta
     5401 gagaacgcca aactactcgg tagatggcga gataacgcgg cactttaagc caaatgatct
     5461 tatctgcttc tttaatcctt tcctctaatg tagaagtata atttccttca acgatccatg
     5521 acggattaga taccataaac aattgctgtt cttgcaaaaa ccactttttt gcctgaatac
     5581 tgtagtctgt tgtatgccat aaaaggtcta gcggcagtag cggaaagtcg gtgatttctt
     5641 tgatcttcct tgcgagggtc gattttcccg acccactttg tccaatcacg atgatcttca
     5701 ttcttctccc tcacttctct ttggaatttg gttcgatcat accacttata acgccgcaaa
     5761 aaaacaaggg actgtgacaa aagtcgtgtc aaagtccctt gtttcgaa
//
LOCUS       DADGHT010000132         5588 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.134, whole genome shotgun sequence.
ACCESSION   DADGHT010000132 DADGHT010000000
VERSION     DADGHT010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.134"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..642
                     /locus_tag="JX887_002601"
     CDS             <1..642
                     /locus_tag="JX887_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAX1258532.1"
                     /translation="AESFEKKHQHVLRDIDALKKDVSNFGQMFVEGNEPDSYGRNRRV
                     FFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIRKNTVPQTIEDMMIYQLEEM
                     KDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGKESRAYEEISKKVFSKFWSE
                     FKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEIDQLNRQQRLFGDDNE"
     gene            820..1161
                     /locus_tag="JX887_002602"
     CDS             820..1161
                     /locus_tag="JX887_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258533.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            1154..1825
                     /locus_tag="JX887_002603"
     CDS             1154..1825
                     /locus_tag="JX887_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAX1258534.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            1831..2523
                     /locus_tag="JX887_002604"
     CDS             1831..2523
                     /locus_tag="JX887_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258535.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
     gene            2520..3269
                     /locus_tag="JX887_002605"
     CDS             2520..3269
                     /locus_tag="JX887_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1258536.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            3281..3550
                     /locus_tag="JX887_002606"
     CDS             3281..3550
                     /locus_tag="JX887_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258537.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            3713..4012
                     /locus_tag="JX887_002607"
     CDS             3713..4012
                     /locus_tag="JX887_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258538.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            4012..4314
                     /locus_tag="JX887_002608"
     CDS             4012..4314
                     /locus_tag="JX887_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258539.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            4354..4719
                     /locus_tag="JX887_002609"
     CDS             4354..4719
                     /locus_tag="JX887_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258540.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            5346..5528
                     /locus_tag="JX887_002610"
     CDS             5346..5528
                     /locus_tag="JX887_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258541.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
BASE COUNT         2060 a          880 c         1197 g         1451 t
ORIGIN      
        1 gcagaaagct tcgagaaaaa acatcaacat gttttaagag atattgatgc actaaaaaaa
       61 gatgtgtcca attttggaca gatgtttgta gaaggtaatg aaccagattc atatggcaga
      121 aatcgacgag ttttcttcat tagtagagat ggatttttct tgctggctat ggggtttaca
      181 ggaaagaaag ctatctactt caaacaaaaa tacattgaag cattcaacga aatggaagat
      241 gttattcgca agaatactgt tcctcaaaca attgaagata tgatgatcta tcaattagaa
      301 gaaatgaaag atgttaaaaa agatgtttcc atgcttaaag atactatgcg aattagcgga
      361 caacaagagt ttgaaattaa gcaaaaagga aatatgaaag ttatgggagt tctaggggga
      421 aaagaaagcc gagcttatga agaaatcagc aaaaaagtat tctcaaaatt ttggtctgaa
      481 tttaaacgta ccttttcaat cccaagatat ggcgagttac ctcgtaagag attcgatgat
      541 gctgtttcat ttattgaaat gtggttgcca gaaactgcga tccgtatgga aattgatcaa
      601 ctgaacagac aacagagact ttttggtgat gacaatgaat agagctgaag cgctaagaat
      661 agggacggca attgctaatt gctggtggaa atactataaa ccaatcatcc taagccaaca
      721 acatattgac aagcaaaaag catggcaaca aataaaaaag tgactccgcc ggcaagcaaa
      781 gagtcacaaa gaaaacacat cataaggaga ttttagcata tggaaaaaga actttccact
      841 ctagatcaat atttgattga tcctgattgg ggcaagccga aaattgagga aacaagtggt
      901 cgaaaaatca gacgaaatct tttgacgaat gaagaactag cttgggatca agatgattta
      961 ggcaaccatg taactatttg ggatcatgtt tatcttatcc atctatcgaa gcattcgaat
     1021 aaacctgaat atatttacgt catcgaagat ggcttgattg atgcgctaga agagtacgac
     1081 agagataact tgattgatat ctcttattac ggaccaggta agaaatacat tgctgaaatg
     1141 gaggcagaat ttgatgagtg aaatcaaagg gacaacgaac tttgaaaaac tttttagtcg
     1201 taagttaaat aaaattctca agaaaaaagg aaattttgat tatttatctt gggctcacgc
     1261 gtgggagatt atgaaaaaga atgatccaca ggcaacggta actattaatg agtacaaaca
     1321 ctacagggtt gtttctggaa ctcatcaaga ctttcttgtt gaggaatata aaccttttct
     1381 tatggatgaa actgggactt atgtatctgt ctcagtaacg gttaaaggac acacggaaac
     1441 cgaattattt cctgttttag attatcgaaa ccaaccagtt gttaaaccaa atgcaatgca
     1501 aatcaataac tcattgaagc gatgctttgt gaaagcattg gctctacacg gactgggatt
     1561 atatgtattt caaggggaag atattccaac accacctaga atcgatacaa agaaattaaa
     1621 catgctagag acgattctag aagctttcaa tgagcagatg ggtaaagata tgaccaaaac
     1681 cttaatcgaa tatgttaatg agcagacaga taaattaggg ctcttagctg ataacgttga
     1741 aactattgaa cagttaagct atgagcaatg tgccttgatg gagcgagcaa tagcagctaa
     1801 gagaaaagaa ttagataaga agtgatatga gtgtttaaac cattaatcga ttcatattca
     1861 gcggttctga aaaagttcaa aggaaaagac ataagcgcaa ccatcaatga ggaagtgaac
     1921 attgatcgac taaagacgat gtatgacggc tacgatggtg atcgagtcat tgaaattcgt
     1981 tttattgatc ctagacgttt caccgtacag caacgaaact tcatctatgc gctgataggc
     2041 gatattttta tcgatacagg catgccaacg gacttctgga aggaattctt ctactttcgt
     2101 tttgaaggtg tcacagggcg caaaataagc ctgaaagacg aatcgaatac aactgtgagt
     2161 gatgccaatg tcttagcaaa tatcatctta gatttcatct ttgaacatca tattcctttc
     2221 aaagaaggct atgagatttt acctgcgaat caagaatatt acttctacaa atgcatcaca
     2281 aaaagagtct gctgcatctg tggcaaaaca ggagctgaca tcgatcactt tgacaaagcg
     2341 ctaggaagac gaaagcgcaa agaagttgat catgcagagt acacatttgc agcactctgc
     2401 agaatccatc acacagagaa gcacaaaata ggtgtgatta atttcaaaaa taaatatcaa
     2461 atcaaaggga tcaaattaaa ccagaaaaca atcaaaaagt taaatattgg aggggaaaaa
     2521 tgacagaaca tcgaagttat tatgcgatta taccagccaa cgtaaggtac gacaaaagac
     2581 ttaaaccaaa tactaagttg ttatacggag agataacggc cttgtgtaat gaaagaggct
     2641 tttgttgggc aggcaatgag tactttgcag atttatatgg tgtgaataaa gagaccatat
     2701 cgcgatgggt aagtgatttg attaagtttg gatacttgaa tcgggaaatc atttacaaag
     2761 agggtaccaa tcaaataatc aataggtacc tacgaattaa tcaataccct attgacgaaa
     2821 aacgcaatac ccctattgac gaaaaagtca aagataataa tacatctatt aataatacat
     2881 ttaataatac aaaagaatat ataagagagt taccgccttc gaaaaaatcg aaggctaagc
     2941 ccgtccgtca taaatacgga gagtataaaa atgttctttt gtcagatgag cagatggaga
     3001 aactcaaaac agaattccct aatgattacc aagagcgaat cgaacgactg tcagagtatt
     3061 gtgaatcatc tggtaagact tataaaaact atttggcaac tattcgaagt tgggcaagga
     3121 aagaaaaaag tgaacctaag aacgcaagca gtggatacaa gcgcacagga agacgagaga
     3181 agcttcctga atgggcaatc gaccaagaag cctatctcaa gaaaaaagcg ctagaacgag
     3241 ctaatagaca atcaaaagca ccattctaag aggtggaaaa atgaagatcg attatctaga
     3301 actaattaat gaaatagcga attataaaaa gggcgaggaa ttagacgtcc tgagagacgt
     3361 atatgatcaa ctcgaagaag ctggaattga aggaattaag aatgatcgtt cgagttggag
     3421 taaactcaga tactatttcg cactctatat cgatggaacg caattaagaa atttagcata
     3481 taccaaatta ctattcattg attgtgttaa aggcttgcaa aaacatctta atgaacttga
     3541 gcaggtgtaa acaagatgga cctaaagaca tttacagcac agatcgaatt aatgcatcaa
     3601 gaagctttaa gacaaagtgt gtcgtacgaa gacaagtggc tcaacacatt tcatggcgga
     3661 cgtgagagcg cacttgatca agtactcaaa ttactgaaag gagaatgtcg ggatggataa
     3721 gaaagcggca atgcagcgaa ttatcgaatt gacttattca gaagattggc aggaagataa
     3781 aaaaatagtt gcagaagtcc aaaagctcgg taaatcaatg tggactgaaa agcccaaacg
     3841 gagaacgccg agaaagattg caatctggca tggtgatcga attctagtaa cgggtaccgc
     3901 taaacagtta tctgaaatta ctggtctgag caaaaatatt atttgggata gagctaggag
     3961 cttatggatt gattcaaaag gaagacagtt taggtatgtg gaggagaaat aatggacgaa
     4021 ctaatcgcga aagtagagca gtgggcaaaa gataagggat tggatcaagc ggatttcagc
     4081 aagcaaatgt taaaaacggt cgaagaaatc ggggaagttg ccgcttctct agctagaaaa
     4141 gatgaacatg gtttaagaga cggaattggc gatgtagtag taaccttgat catcttggca
     4201 atgcaaaatg atatggattt atacgagtgc ttggattttg cttatgacga aatcaaaggt
     4261 cggactggaa agatggtcaa tggtgttttc gttaagtcca gtgacctgaa ataattccat
     4321 taatggaaga aataactgaa taggaggata gacatgattg atgcaaaaca agtgcaaaaa
     4381 cagaaagatg gaatgttgat gtttgaagca tatgttctac catttcttaa tcaatttgaa
     4441 gttttggaat gctctgccag cggagaagaa ttggagtatg ttgtaattcg tgaaaccaaa
     4501 gaaaacgttc agaagctaaa cgaatttctt tgcactatta actgttggga tatgatagct
     4561 ccaggatttt tatgtccagc tatgggagaa tttttggaat attgtcgtct tgaagatgca
     4621 ggcactttgg atttagctta tctggtatac aactacctaa acatcaacac agatcatttg
     4681 tggtttggca ctgccgaaag aaaatgggta gtccgctaac caccaatatc aatgaaaaaa
     4741 ggcggtttcc tgaaagtgga attgccgcca ttgctgtaag gttctttacg cgactcaagg
     4801 tcacagaaat ataaatgcaa atctcttttg aagtgatcca aagctctcgg aaaatggaag
     4861 ttttttgttt caaagaataa atgagatttg cgtcaagaac ctgagagtta tttccaaaaa
     4921 agcttccaaa gaaccgaatg agctaaggac atcatgtgta aacacataat atagctctcc
     4981 tttcacggct aatcataaca tgaaaaatat tcgatgtcag taggaaaaaa ggtgaattat
     5041 gaaaagaata ttaaattatc ccggcagtaa cagattctgc aattaaactc cgaagctgat
     5101 gtatcagtat caactgtaga atattatgag cgtggagaaa gtcaagcagt cacaaatgta
     5161 aaaatcgata acgtcaacgg tcttatctgt ttagatgaag gcgatagtat gaatgaaatt
     5221 gctgcagacc atgaattatc agaaactgct ttaattgatc aaatcgaatt agctagacaa
     5281 tactttgttc catatgcaga tacctggtcc aagcataaga atgacatcat ttttccagag
     5341 gaacaatgag agcaactgat ccagtaatta tccttgagga agccaaattt atttggactc
     5401 acgaagagat agagcaagca cgcttgctct tttctcaagg agttaagccg agcaaagtag
     5461 ctgaaataat gggtcaaaag attcttgatg tcggattgct tttgctccat ctagcagaaa
     5521 aaatttgatt tgaggtgaaa atgatgattc aacttgcagg catccaaaca gggaaaattt
     5581 atttttct
//
LOCUS       DADGHT010000133         5570 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.135, whole genome shotgun sequence.
ACCESSION   DADGHT010000133 DADGHT010000000
VERSION     DADGHT010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.135"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            128..2187
                     /locus_tag="JX887_002611"
                     /pseudo
     CDS             128..2187
                     /locus_tag="JX887_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2270..2839
                     /locus_tag="JX887_002612"
     CDS             2270..2839
                     /locus_tag="JX887_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1258542.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(3014..3820)
                     /locus_tag="JX887_002613"
     CDS             complement(3014..3820)
                     /locus_tag="JX887_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258543.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3958..5472
                     /locus_tag="JX887_002614"
     CDS             3958..5472
                     /locus_tag="JX887_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAX1258544.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
BASE COUNT         1984 a          964 c         1126 g         1496 t
ORIGIN      
        1 acaataaaaa atcaaaaaaa atactctcct aatagtccat cttcttttga ttttatttat
       61 ataatgaaat catcttatga aaattactac ttcatgttta gacaagagta gggaggacta
      121 agaataaatg tgttcaaaaa gacgttcaaa acaactaaat aaacacgctt gtcgtttaga
      181 taaggaacgg tcgtgttctg aaaaacacta cgttaagttt atgatgcgca cgatgctgat
      241 cagtttatct gtaggtgtct atatgcatgt acccgttcag gcaacgacac aaaccatcaa
      301 ggtcgtacgt acctctgttt ctgagaccac tgattcccct atcactatta ctcatacttt
      361 cactgatgca aatggaaaac agctacttcc tgcattgact tcctataata aagtcagtta
      421 tcctccaacg ataaaccact actggttaat tcctaacaaa acattatgga catcggaaac
      481 cggaagcagt gtgccgcttt ctatcttttc cgatatgact gatcctacaa aaggtgatca
      541 gttaaaacag atcactgata ttttgaatca tgctttgaca gatataaagg acggtggaag
      601 cgcacaagtt tcttatgtat atgaaaaaga ttattcacag tttgaaagaa agaaaatcga
      661 tgttctggca gggacaaaag tttcgatatc tgatctggta gaaaggctga agaacgcaga
      721 tggaacacaa ggagatatgt ccaaagtaat ttcaaacaat gggaatatcg tggatacgac
      781 taatacagga acatctacta tttccttgtc ctattttgat ccaattgctt taaaaacaat
      841 gactgcatct gctgtgatcc atgttcgtgc tgatcaaaca gctatcaaag gaaaagatct
      901 tcacttaaga acaggagaga gttacgcccc taaagatctt gttgaatatg taacaaaaag
      961 cgatggaact tcaggaaata aagaagaaat caaaatgaac gggacagtag atactacaac
     1021 tccgggagaa tatcccgttg tattaactta tatagactcg aaaacatcaa atgtggcaga
     1081 aacaacagct gtagtttatg tagaagcatc tgctgcttca tcgactgtca tcactcattt
     1141 tatagatagt caaacaaata aagaacttca agcagaaaca catatgagta gtgtaaatcg
     1201 tattcctgat ttgcgcctac ctgctgaatt ttctgatcga gtgccaaata tagatttatc
     1261 gacttatgaa caaaatggga aagtcacttc tatttctgat tggatgcaag caaacggatt
     1321 agacagaaaa agtcactggt cggagatcct tgaagtactt cactcagaac tgatgaataa
     1381 taggaagcaa tcaggagggg aaattacctt tacttatgtt tatataccag acaatcgttc
     1441 attagaaggt catgatctta ttgttcatcc aaacgaaaaa ataaacaaag aagagttgat
     1501 ccaatcagca acaaattcct taggtaaacc cgtaccgtta aaggatgtat cggttacaat
     1561 caatgaagta ccattggagg atggttattt gaccaaacaa acaggtgatt ttacgattat
     1621 gtatagttat catgacccgt attcactcca agaactccat gctcagtcac tattacatgt
     1681 tttaccatta aacaaacaga tagatcaaaa agaacaaaaa agacaagaag aaagcttgtc
     1741 agaaaaaaac aacaaatggc tcatgcagtt tctccaacag ggaaagtaaa acaaacaaga
     1801 agcctagagt tagcaagaat atctagaaaa atctcagaat ctaataaaac gataaggcaa
     1861 gaagctcatt tggccccaca agtttctgga ttggaaaatg aaattttaga gcctaaaata
     1921 aaacaacaat cagaaaaaga atttgttgct aaacagtcgg aagatcagaa ggaatcagat
     1981 gaccagaagg aaacgaagaa aaaacgcttg tcaactattg attccaccga tgagcatctg
     2041 cagccgcaag taccacttcc tagtccggga acacccgcac ctggtggagg tattccttct
     2101 tctgctttag gagatttcat gcgaggtatg gcaggaacat gggtatacgc taatcgaaat
     2161 gaatttgacg cagatgactg gttctgattt atatctctat ctgttatagt caaataagta
     2221 gctgagtcat atgttatttg gcataatgga gacgaggagg gatagaaaaa tgttagataa
     2281 aacgttacct tacgcagaaa tctggatgac aagaccactt caacaaaatg ttccaatcac
     2341 gcctttagcg gaaggttttg aatttcgatt ttatcaaaaa gaagatgaat ctgcttgggc
     2401 ggagattgag acttccgttg gggaatttca aacgacagat gaagcacttg agtattttca
     2461 acaaaacttt gctccttatc ctgaagaact tgaaagaagg atgttttttg tagagacaaa
     2521 aaaaggagaa aaagtagcaa cctgtaccgc ttggcgaaaa aaatcaagag agcaagtgta
     2581 tccggttttt cattggttag cagtgaaacc agattaccaa ggaaaagggc tcgcaaaagc
     2641 attgactgcc agagtcttgc aagaatttcc taccctccat acggacggac caatctatct
     2701 tcacacacag acatggagcc atcaggcgat tgctctttat aaaaaaatgg gttttacttt
     2761 tattgctgaa aatctagacg gcacacctaa tccagattat gaaaaagtta tgcaggtttt
     2821 aagtaaatta gataaataac gaaatggtga aataagtcct cagtattggg ataaaaaacg
     2881 aaatagtcat tcctcatatc ttactttttt gagttaatac tatcggataa ctaatggcat
     2941 gccatacatt caaaaaagaa ggggcagtga caaaagtatt gtcactgccc cttctcttgt
     3001 tttttagcat gttttatcgt ttgatttttt taggaataaa attcttgatg aacgtaaatt
     3061 tttggtaatc gtttcgacta tagaggtaac caaatacact gaaaacaact gctccaataa
     3121 aattaacaaa taaatccttc atagtatcca tgattcccac gtctaagtaa ccattttgga
     3181 tgattgtttt atctgtttta ccatctgcat tttgactttc aatgattgtc cgagtgatat
     3241 ctggaacatg atagacagtg tttccgtctt tacttaactc cacactattg atttgctgga
     3301 tgatcgtatc tttttgcata tcgaattgca gtaatttatc tgctgaaaat tccacaaact
     3361 cccacataac accaactgtc atcgaaaaac agaaggaaac aactgctagt aataaaggag
     3421 tcaagttcat ggtttttgta tttttattga gcaaataaac aagggaaaag ccgacacccc
     3481 cagctaaaaa tccgctgaat gcatgtagaa aagtatccca cattgaaaaa tagccataaa
     3541 aatcacttaa ctctcctaaa actgttgaac taaaaataaa agataacaaa atgatttcta
     3601 gcatatttgg aatctgtatc tttaatatct tttccagaaa ataagggatt tcaaataaaa
     3661 ttaatgtcag taataaaagc attgtatttc cccagtgttg gttccagacc tgatccacta
     3721 gcataataac gacgatgata cgtaataaaa tatagattcc gtttgtgatt ctacctgcag
     3781 tttttgtact gttcgtaaaa aaggttttca aatgattcat aaaataactc cttcatgtat
     3841 atccttaatt atactaagaa gcgtgtgttt accaaagcta tatgacttaa agaaaaacag
     3901 agttgatatt gtgaaaaaaa tcacttaata tagtataagg agaaaagggg gatacaaatg
     3961 aaaaaattag ttgctggttt attaacagcc gttgcacttc ttgctatgag cgcatgcggc
     4021 gcagatcaga aaaatacagc gcagacaagt tctagtacga aggaatctgc cgaagtatca
     4081 tcaggcgctt ctgaacaagt atatacagat ccaaaagaaa tgaaagaatc ttatgatgtc
     4141 gtgattattg gagctggtgg tgcagggatg gcagcagcta tcgaagcaaa agatgctggg
     4201 ttgaatccag taattttgga aaagatgcct gttgccggag gaaacacatc taaatcatca
     4261 agcggtatga atgcttcaga aacaaaattt caaaaagaag aaggaatcaa agactcgaat
     4321 gatgccttct atgaagaaac gctaaaaggt ggtggaggaa cgaatgataa agaaatgctt
     4381 cgatactttg tcgatcactc tgctgatgcg gtcgattggc tagatcaaaa cggtatcaaa
     4441 ctggacaact taacgatcac tggagggatg agtgaaaaga ggacacatcg tccgtctgat
     4501 ggctcggcta ttggtggata cttagtggag gggttattga ataacgtcca tgagcgggaa
     4561 atccctattt ttgtcaacgc agatgtgaca gacattaaga aaaatgggga aacggtcaat
     4621 gaagtgactg tacatgttca aggagaagaa ccaaaagagg tcaccggaaa agcaatcgta
     4681 gttaccacag gcggttttgg tgccagcaaa gaatttattg aaaaatatcg tcccgattta
     4741 gctgattata ttacgacaaa tcaagaagga tcaactggag atggtatcac catgattgaa
     4801 aaattaggtg gacaaaccgt tgatatggat aaaatacaaa ttcatccaac tgtgcagcag
     4861 gatgaggggg tcttgattgg tgaggttgtt cgcggagaag gagcaatctt ggtcgatcaa
     4921 gaggggaaaa gatttgtcaa tgaaatggat acaagggata aagtatctgc agcaattaca
     4981 gcattgcctg aaaaatcagc ttatttgatt tttgaccaag gcgtgcgtga tcgtgccaca
     5041 gctattgaat tttatgacca aaaaggatat gtcacaactg gaaagacaat ggaagaatta
     5101 gcagaaaaaa tcgatttacc aaaagaaaca ctagcaaaaa cagttgatgg atggaatacg
     5161 gatgttgcgg agaaaaaaga tgctcaattc aaccgtgcca cagccatgga acatgactta
     5221 tcgtctccga attattatgc gatcaaaatc gcaccaggaa tccattacac gatgggcggt
     5281 gtgaaaatca atacgaacac tgaagtatta gataaagaaa accagccaat tagggggtta
     5341 tatgctgctg gtgaagtcac aggtggctta catggaaaca accggatcgg tggaaattca
     5401 gttgcggaga tcattatttt tgggcgacaa gcgggcatac aagcagctcg atttgcttcg
     5461 gaaaatgaat gaaatagaac gtaaataaaa agaggttgtg aaatcagcgt tttgagctaa
     5521 taccgagggt cagctgattg aacactgttt agtgaagagg ttgtgaaaaa
//
LOCUS       DADGHT010000134         5505 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.136, whole genome shotgun sequence.
ACCESSION   DADGHT010000134 DADGHT010000000
VERSION     DADGHT010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.136"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            279..1127
                     /locus_tag="JX887_002615"
     CDS             279..1127
                     /locus_tag="JX887_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258545.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(1298..1639)
                     /locus_tag="JX887_002616"
     CDS             complement(1298..1639)
                     /locus_tag="JX887_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HAX1258546.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            1725..2432
                     /locus_tag="JX887_002617"
     CDS             1725..2432
                     /locus_tag="JX887_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAX1258547.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            2419..2742
                     /locus_tag="JX887_002618"
     CDS             2419..2742
                     /locus_tag="JX887_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAX1258548.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(2831..3868)
                     /locus_tag="JX887_002619"
     CDS             complement(2831..3868)
                     /locus_tag="JX887_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAX1258549.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(4315..5298)
                     /locus_tag="JX887_002620"
     CDS             complement(4315..5298)
                     /locus_tag="JX887_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAX1258550.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
BASE COUNT         1609 a         1142 c          982 g         1772 t
ORIGIN      
        1 tctttgcgat acatcatacc tcttttatca attggaacaa ttatttattt ctaacaaaat
       61 cacttcattt ttgtcagata aataaaaaac aaaaaaagtt ccatctttaa aacacgctat
      121 tcttttactt tttctcacat tctctaagaa aagaaaagga gaatgaattt ttgacaattc
      181 gagcaaaagt gattatcaaa tatgtaaaat cagctacttt tttcttaaac gtttctttat
      241 actaaatata aataagtgtt tcatgaaagg agaactagat gaataattgg cttgagtatt
      301 ttcctgaaaa cgttttggaa cgcggttaca gctatcatct gcacggtttt gtccgtcatt
      361 tgaactatac aagcaagtac ttgtccgcaa cagtttctgg cacggaagat tataaggtag
      421 tgatcacttg ggatgaaaag accaacatga cttgtgattg tctatatgcc atagaaggaa
      481 aaaaatgcaa acacatggct gctgtcttat tcgcttacga agaacgtcca ataaaaaaat
      541 ccaactactc actttccgaa ctctcgtccc ttgtttcctc cgctagttcc tctcttgtac
      601 gggagctttt aacagagatt cttatagaac atccgcactt tatcgaacgc ttcaaagtta
      661 agatgccatt tcatgcaata aattattcag ataaattaac aactatcatc cataaatacg
      721 atcatattat caagaaaaac aaaaacagga aaacagcgaa gttcatcatg gagatgcgaa
      781 agttcatcca agaagcagtt gaatcgctta ttcagcaaaa tgcctatctt cccgcattcg
      841 aattgatcaa tgaagtgatt gctactctcg aaacattcta ttgggagcct gaggatgaac
      901 gaacccttct tctgatagag gactgttatt atttatggaa agaattatta gcagaagcac
      961 ctcatgcaga aaaaaggcaa atgttctctt ggttcgtctg ccaagtcgat catactgacg
     1021 cctcttattc aaaacgctac tctataaaaa tcctgaaaga agactttcgg gaaaaagaat
     1081 tttctaacca aaagaaaaaa atagataaaa aactaaagaa acggtaaaga aagacgattt
     1141 caatgaaaaa tagcaagtaa acgataacaa ccatcctaaa tccacaagaa atacagcaga
     1201 ccttgcttta aaaacacgaa tcatgcaaag gatgaagtaa agaagactta acgcgtaccc
     1261 aatattagtc atttgactat taggtacgcg ttttgtttta taagtcatga caaatttcct
     1321 tcgttgctgg atagattttc cggcattgtt gatagatttt atgatacttt tctacatttt
     1381 gtaagagagg ttccactgca tctgtatatt ggataaaatt ctgacaacaa ctttcaggtg
     1441 tgtcgaacca ccctaaccct agtgcagcaa tcattgttgc gcctaatgca ggtccttcct
     1501 ccacacttaa acaatagacc gttgcatcga aaatatcagc ttggatttgt agccatgcaa
     1561 gatttttcgc gcctcctccc accgaaacaa tacgtgtaaa tctgcgaccc gctagttctt
     1621 tacgtttcaa tcccaccatt gacaaatgct cattaaaaat ttagaatatt cacaagttta
     1681 acgacaatta tgaaaattta tgtcgtgcta aaggagtttt gttattggat gaaaagttag
     1741 atataaaaac tgcgatcaaa gacacgttac ctaccgtttt cggttatatc ggtattggac
     1801 ttgcatttgg tatcgttggg aaagctgccg gatttcatcc actagtcgtc acgttgatgt
     1861 ccctgctggt ctatgctggt tctgcccaat ttatcacagt cagcatgctt gctagtcaca
     1921 gcccattgct ttccatcgtt ttctcgacct ttctagtcaa ttcccgaatg attctgatga
     1981 gtatgacgat tgctccttat ttcaagaaaa atcggctgct tcaaaatctg ctgattggca
     2041 cattgctgac agatgaaagt ttcgcactgg gaatgaataa attgaactat actggacaaa
     2101 agttaaactt tcgttggatg aatacagcta attggatttc ttatttgacg tgggtgggtt
     2161 cttctcttgt tggcgcactt ttagggaatt ttattactga tccgaaaaag tttggtttgg
     2221 atttcgccat cgtcgctatg tttatcgggt tactttatct tcaagtcatt tctgatagaa
     2281 acacctctaa acgattacag ttgatcctga ttggtctcac tttgattctg gtatatgtcg
     2341 gactgatttt tatcccaagc aacttagtga ttgtagttgt aacactgatt gggtgcggat
     2401 tgggggtgtg gatcaaacat gccttctttt gagtttacat tgctgactat tttaggttgt
     2461 actttagcaa cttggctttc tagggtccta ccatttgtct tactgaaaaa attcgattta
     2521 ccgcaaccgt tgcttgagta tttaagtttt gtcccgatcg tcattatgtc tgctttatgg
     2581 ttcagcagtc tatttaccca aaatatcgga catctgccgc agatcaatct cgaaaatgct
     2641 ttggcttcag ttcctacact tttagctgct attctttcaa aaagcttatt ggtgatcgtc
     2701 ttggcaggaa ttctttccct ttcgttgatt cgcttattat aaataaaaaa acaagagctt
     2761 atggcaaatt actgtcatgc gctcttgttt ttatcaaagt caaataagaa aaaaatcggc
     2821 gtattcttgc ttatccgttg aacggaccac taacaacgac ttttcctaac atatgtcctg
     2881 tttctacgtc tttggttgct tgtttcaagt tcttcgcatt catcccatct gaatagacct
     2941 tgctcaatgt actgcggata atcccttcat ttgctaaagc agcaatgtgc gctaaagctt
     3001 ctccttgcgt ttcgatttca tagttatagt ctgttttagc gaacatatac tcccagtcga
     3061 agctgataga ttggtttttc caaacaccta tatctaacgg ctctttgatc cctacgatcg
     3121 ttcccacatg tccaaatggt cggacaaggt gcttgatttg atcaaagtag cgggtaatat
     3181 cgaataatac agcgacatac tctacttgat cgattcctaa ttcacgaaaa cttttactta
     3241 agtcgtgatg ataatcgatt ggatagtcta cacctgtttt tttcagccat tcaaaattct
     3301 tcggacttgc agtcgcgtag acttctaggc cagcccaatg cgctagttga ttcaaaatcg
     3361 aaccgacgcc cccggatccg ttgatcacta agattttttt cccgcgattg gcattttctt
     3421 ctggagttag accaaatttt tcaaataaca attcataagc ggtcaatgag gtcaacggca
     3481 aggctgcagc ttcttcatct gaaagatttt ttggtgcaag agcgacaata cgttcgtcaa
     3541 ctagttggta ttcttgattg cttcctgctc ttgttgttgt acctgcgtaa aaaacgcgat
     3601 cgccgacaga aaatttttgc acttcgtcac ctacagcaac aactttcccg actccatcaa
     3661 aacctaagat acgtaaagca tttcttatcc cgttatcttg gcgaagtttc gtatcgacag
     3721 gattaacaga tactgcgttg acttttacca gaagatcccg tgaactgggt acaggtatct
     3781 gttctttttc atcaataaag ctttttggat catcgatcgg caacccttca taaaaaccga
     3841 ctaccttcat taattccttt tctgacatac gaattcctcc ttagcttcat caagttggag
     3901 catccataca gtgttcattt caatatatat agtatgctat ttgttccacc ttttttattc
     3961 atcataatta ttctcttact taaagtaaac tatttgcact tttttggtta aaaaagaggt
     4021 tgcgacaaga cttttgtcac aacctcttat aaacggtgtt ctcctaccaa ctcttcggtc
     4081 acaagtcaaa atattcatca aacatgagaa gctgtttttt gaaattgctc cttgtgactc
     4141 agagttaaac ggcaggctca caacctctga tataaacggt gttcaatcaa ctgaccctcg
     4201 gtattagctc aaaaaacgac aaaatatgaa gagctatttt tgtttggctg ttcttattac
     4261 ttgatacagg acagcttttt cacgacctct aattcacggt gttcaagcaa gaaatcattg
     4321 ttcactgaaa agcgttggat gttctttttc aaaggtctct aagatctctc gtacttcatc
     4381 agtagatttc gtattcatca actgaactcg caagtcattt gctcctggaa atcctttgat
     4441 atagatttta aagaaacgat gtagtcctgt gatggaacgc gggatgattt ctgaataatg
     4501 atcttgcaga tctagttgca gacgaagtag tccgatcagt tctttttctg tatgttccct
     4561 cgggtctttt tcaaatgcat aaggattctt gaaaatccct cggccaatca tgatgccatc
     4621 aacgccatat ttctcggcca attcttctcc tgtctggcga tcggggatat ctccattgat
     4681 cgtgattagt gtttgtggag cgatttggtc acgtaaagca atgattttag gaatgacttc
     4741 ccaatgtgca tctactttac tcatctcttt acgcgtacgc aaatggacag aaagattggc
     4801 tatatcttga tgaagtaggt gactgatcca ttcttccatc tcagacattt ccgtatagcc
     4861 gatacgcgtc ttgacgctga caggcaaacc gccagcttta gctgcttcaa tcaattgtgc
     4921 cgctacttct ggacgaagga tcaagccact gccttttcca cgttctgcta cattagggac
     4981 tgggcagccc atgttgatat cgattccttg gaagcccatt tctgccatag caatgctcat
     5041 ttctctaaaa aattctggct tgtctcccca aatatgggca accatcggct gttcatcttc
     5101 tgtaaatgtt aatcttcctc gtacactgtc ttttccatct ggatgacaga aactgtctga
     5161 gtttgtaaac tcagtaaaga agacatccgg tgctgctgca tgctttacga catggcgaaa
     5221 tacaacatct gttacatctt ccattggtgc taaaacaaaa aaaggctttg gcagctcttt
     5281 ccaaaaatta gtagtcattt atttgttact ctccattcta tcaagcagtg aagtcgcaat
     5341 ctttctcaaa aacattgtca ttatactagg aaacaaaaaa agaagcaaag tgaacagctt
     5401 aaaagatgtt tctgattgag caaaaaaaag actgtgacaa aaatcttatc acagtccatt
     5461 ttccggaata aatggtgttc aaaagcttgc atctgcggta ataag
//
LOCUS       DADGHT010000135         5444 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.137, whole genome shotgun sequence.
ACCESSION   DADGHT010000135 DADGHT010000000
VERSION     DADGHT010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.137"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..571)
                     /locus_tag="JX887_002621"
     CDS             complement(<1..571)
                     /locus_tag="JX887_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAX1258551.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
     gene            complement(905..992)
                     /locus_tag="JX887_002622"
     tRNA            complement(905..992)
                     /locus_tag="JX887_002622"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(958..960),aa:Ser,seq:cga)
     gene            complement(1137..1703)
                     /locus_tag="JX887_002623"
     CDS             complement(1137..1703)
                     /locus_tag="JX887_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAX1258552.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            1958..3289
                     /locus_tag="JX887_002624"
     CDS             1958..3289
                     /locus_tag="JX887_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAX1258553.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            3255..3605
                     /locus_tag="JX887_002625"
     CDS             3255..3605
                     /locus_tag="JX887_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258554.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(3697..4116)
                     /locus_tag="JX887_002626"
     CDS             complement(3697..4116)
                     /locus_tag="JX887_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAX1258555.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(4117..4461)
                     /locus_tag="JX887_002627"
     CDS             complement(4117..4461)
                     /locus_tag="JX887_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAX1258556.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            4811..5407
                     /locus_tag="JX887_002628"
     CDS             4811..5407
                     /locus_tag="JX887_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAX1258557.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1513 a         1008 c          930 g         1993 t
ORIGIN      
        1 ttccatttga tagcgagcga taattgttca gattaaataa ttgataatca aatggcggat
       61 tatttgtcaa cacaccgaca ggattatcat ataaatgaag tccatctttc atactttcaa
      121 ttactatcga tttttcttta tcagctaata accagtgtaa aggtgacaag ggtagttttt
      181 cactaaaatc gatattgact agattgatag tagccaataa ttctttagct tcgtctatgg
      241 ttgagcattg ccctagtatc catggaataa actcaaatgg tgcaacgtta tcttttcctt
      301 cttgtaattc tttataatca gcattgccag gaaaattcag tcctgccata ctcaaccctt
      361 tttcatttgt agcctcataa tagagtggat agttggatac cccagctgct attcctatca
      421 ttgcataatg tttatctaaa ttttttacct ttctaaaatc gaaacgataa tttcttggag
      481 taatagtgac cacttcatta taagacatct cataatcaaa attccttcca aaataatggt
      541 ctttcgttgc ataagtgatt gcggtacaca tcgtttcccc tcctaaaaca aatcgttttt
      601 acacttttat cttacatcta gtattttttt tatcaaaaaa aggccaaaga agattgattt
      661 actagcattt ataaaaaata gtactcaggg ggaatcaaaa aatattgtag gttaaaagta
      721 caacaataag gggctgtgac aaaagtcttg tcacagcccc ttattccgaa caaacggtgt
      781 tcaaaagctt gcatctgcgg taataagccc aatcaaacga aaaaatagga aaagctattt
      841 ttgtttggcc gttcttatta cttgatgcag gacagcttct tcacaacctc taatcgttga
      901 tataaggaag gtacaggatt tgaacctgcg cgccggtatt agccggttcg ccggatttcg
      961 agtccggtgc attaccactc tgccaacctt ccgtaagtac tatttttaaa cttttttcac
     1021 gaaatgtcaa gcctatttct aatagataaa taacagaaat cgcttttttt agcaaaaaag
     1081 tccattgaca gtttgcagcc aacggactta ccgatcaaat tcatactgat agaacactat
     1141 ctgattattt caggattatc taatgctaaa atcgagtcaa ttgtccgttt gatcagtgca
     1201 atgatttgtt cttctgttgg atgcatgatg tttgatgaca tcaatgacgc taagccagtc
     1261 actgctaccc atgtaccagt atgcagagca tcgacatatt catccgataa ttgattgtat
     1321 ctttcatctt ctttaactat ttcacggaaa taattgtatg aaaaatcatg cattttcttt
     1381 ccgtccccat gttcatcaat gtacaatgcc atgtaaagac tatgatgctt ttttgcaaag
     1441 tagatatagt tcaaaccgag atcaatgatt ttatcaccag tacgttcaat agggaaaaca
     1501 tcttctttta gttgttcaaa gatagaatcc agcaacgtat tttttaaatc ttccatgttt
     1561 ttgaattcca gataaatcgg ctgtgtcgaa atccccatct ttttagcaat atttctcgca
     1621 gtaaatcctt taaacccttc ctttgcaaca acatcataag cagcttttag aatttgatcc
     1681 ttggtataga cttttcttct cattaaaact cccccacttc tttactgcag tatatgttgt
     1741 tttattgtac cctattttta gcattttttg caaacatttt actcaaaacg ttatatttta
     1801 aatttttttc agtcttcttt aacttttttt tgcaaaatta aaaaaatttg gttaaattca
     1861 atgggttccc ttacattttt agttttgacc taaatgatag ttgtccaaat ctttcatttc
     1921 aagttatagt taaagaaaat gaaaaagaag gtgtgtaatg gaaaacgaaa ctgacgttat
     1981 ttatattcat cctcaaaaac gaatcgtttc acagaaaaga aagtattttt atcttggttt
     2041 tacaggtgtt ttttttcttt ttattggctt gctttctaat actcctactg ataattggag
     2101 tggattgcta actattctta cctcgccaag caatcttttg acagattatt ttgctttagg
     2161 tgttttcgga agcgcattca taaatgtagg gattttgacc ttactttctg tgcttttagc
     2221 ttatcggcac aaggtgattt taaacggtcc cttatttgct tcgattctaa cagttaccgg
     2281 tttctctttt tttggcaaaa acctttataa ttctatctca atcattttag gtgtgtatct
     2341 atacgctgta tttgtcaata aacctttttc tcagtacatc atgatcggac tgtttggtag
     2401 cgtattatca ccggtcgtta gttatatcac ttttggtatg cgttttcctt tactgatagg
     2461 tattttattg gggaatttag ctggcatagc aattggtata cttcttccgc ccttagctgc
     2521 tcaaacttta gttttccatc gtggattcac actttataat attggattca cctctgggtt
     2581 gattgcgatg acttttactg ctgttttgag gttattcagc tattcaatcg tcgaaaatac
     2641 attggttttc aatgaatatc actttcctct catttggatt atttttggct ttttttcgct
     2701 gacagtcgga attggtttct attataattc ctttcggctt tcggggattc gagaaatttt
     2761 cgattcatct ggaaaattga caactgattt cattgctaat tctggtattg gtgctacttt
     2821 gatcaacatg ggcttagttg gtctgatgct gtcttcttat gttttgctgg ttggcggtca
     2881 gttaaatgga cctgtcatcg gtgctatttt atctgcggtg ggtttcagtg cttttggttg
     2941 tcatttaaaa aacagttttc cgatactagt cggaatattt attgcttctt tgtttggaac
     3001 ttttcatgag atcaccagta ctggcatgct tgttgcagct gtgtttggga caggtcttgc
     3061 gcccataagc ggtttttacg gcagttttta cggtgtaata gctggtgtgc tacatattgc
     3121 tcttgtccat aacgtcagca ctttgcacgg aggactaaat ctatataaca gtggtttttc
     3181 aactggtttc gttgcaggta tccttgtacc gatactagat aactttaccg ctgtcagaaa
     3241 ggaaaaaaag acacttggaa aaagaattat caaaaagaat catcgatgag cttcttactt
     3301 atttatattc ccatgaaata actgaaatac gtattggagt agaatttgct gaggaagggc
     3361 ttttcataga gatacagggt acggcagaaa ctcagccaga agatttagat gtacttgctg
     3421 atttgctgaa caatcctcgg gaccctagta tggaaatcta ctatcaagaa ctattaggta
     3481 atccccgaca tgatcgggaa gattatcatc tgttaggtag tttgattgat gacgtggaaa
     3541 tcatgtatgc ccagccgatt atcaatatta agatctttcg acgtgcttct cattcctatt
     3601 attaacccta ttttctattt ataaaagact gaatcaaaaa agcagctcct gaaagttcga
     3661 ttaaaatcta ctttcaggag ctgttcaagc ttgacattat tgattttcca atccttcata
     3721 cacttcatct gttacaggtt ctaaaaactc tgaattacca gcagtgatcg ccaaatgttc
     3781 aaaccaactg tcttttgtcg caccatgcca atgtttaatc cctttgtgcg ttacgacgac
     3841 atctccagcc attaatcgtc ttgctggctt tccttcttcc tgataccagc cttctcctcc
     3901 ggtcacaagt aagatttgat agccgtctgt atggacatgc cagtgattgc gacaacctgg
     3961 ttcaaaagtt acattaccta caccaacaga aacttcggga tcattcacta acatattcag
     4021 atagctttgc ccggtaaata cttgagcgta agcttcgttt ttttcacctg ctggaaaaat
     4081 cacgccattg tgtatttctt cgtgttttgt catcatttac gcctctttct tatcttcgct
     4141 attttcttct aaatagattt cttttgctaa actaaaagct gaccaagctt ttggccattc
     4201 tacataaaaa gctaaatggg taatgatttc tgctatttct tcactagtaa tgccattttg
     4261 cttgccaatc ttcagatgag ctggcaattg ttcaaaattt cctcctgaaa ttaatgcaga
     4321 tatggtgatg atactacgct gatgagcaga taattcttct ctggaccata cttgtccaaa
     4381 taaaacatca tcatttaatt ctgcaaattt tggtgcaaaa tctcctaatt gatctcgtcc
     4441 tgcggtttgt ttttctgcca tttctcttat tctcccttca cgactgttag gtgattcaac
     4501 tatggttcta aggcaacttt attttctatt gtttcttcgc atttcatttt aaatgtagtc
     4561 tttcagcctg tccaatgctt agtttattca gtcgatatgc tttttaagca tagttgctaa
     4621 cgcttttttt attttaaaaa aaacaagtta ttaaataagt ctttagttgg atgttttttt
     4681 gagatcaatc ttttatactt atgatgaact tacaaaattg tttgttttct gtcatatcaa
     4741 aaaatggcgc agttagttgc ttttctagta aagtatagtt aacaaagaac ctctaaggag
     4801 ttgatgaata atgaatattg ctgcctctcg aaaactgata aatttcatat ccattatcgg
     4861 attaggccta tcaatcgcgc tgacgattta ttttattaat ttaggtgttt tcaaagattt
     4921 gaatgcgtta agaggattag taggtgattc catcatttta ggaccgatta tttttgtctt
     4981 catccaaatc ctgcaagtag ttattccaat cattcctgga gggatcagta ctgcagctgg
     5041 tgtcctgata tttggccctt atgctggatt tatctataac tatattggaa tctgcattgg
     5101 ttcgattatc atttttctgc tagggcgtcg ttatggaaag ccattcatac tttccatgat
     5161 tagcgataag acatataaca aatatattgg ctggctggat aatcaaaacc gttttgagaa
     5221 gctgtttgct ctagctattt ttcttccagt tgctcctgac gatgcgttat gtttgatggc
     5281 tggattgaca aacatgtcag tgaaacgata tacactaatc attttgattg ctaaaccact
     5341 gtcgattttc ttatatagta tggccttgat ttatggaggt caatatctaa gtggtcttct
     5401 tggataatat ttattttgta aaattagtca ttgattgaca atgt
//
LOCUS       DADGHT010000136         5312 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.138, whole genome shotgun sequence.
ACCESSION   DADGHT010000136 DADGHT010000000
VERSION     DADGHT010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.138"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="JX887_002629"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="JX887_002629"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAX1258558.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="JX887_002630"
     CDS             complement(1297..2133)
                     /locus_tag="JX887_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1258559.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="JX887_002631"
     CDS             complement(2317..3534)
                     /locus_tag="JX887_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAX1258560.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3917..4000
                     /locus_tag="JX887_002632"
     tRNA            3917..4000
                     /locus_tag="JX887_002632"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..5237)
                     /locus_tag="JX887_002633"
                     /pseudo
     CDS             complement(4240..5237)
                     /locus_tag="JX887_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1654 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca ta
//
LOCUS       DADGHT010000137         5207 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.139, whole genome shotgun sequence.
ACCESSION   DADGHT010000137 DADGHT010000000
VERSION     DADGHT010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.139"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            34..1368
                     /locus_tag="JX887_002634"
     CDS             34..1368
                     /locus_tag="JX887_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258561.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1355..2989
                     /locus_tag="JX887_002635"
     CDS             1355..2989
                     /locus_tag="JX887_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258562.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3164..3997
                     /gene="msrA"
                     /locus_tag="JX887_002636"
     CDS             3164..3997
                     /gene="msrA"
                     /locus_tag="JX887_002636"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAX1258563.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4077..5066
                     /locus_tag="JX887_002637"
     CDS             4077..5066
                     /locus_tag="JX887_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAX1258564.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1825 a          806 c          951 g         1625 t
ORIGIN      
        1 agtttttatt atggagaaaa gttttttaaa aagatagatg ctgctttttt atttagttgt
       61 ttatatactt ttgcaactta tcgaacagtt gatatctatt atcgatccgc aattgcagaa
      121 gcaatcgctc ttacgattat cccagctgtt ttatattatg cttatggatt gatattcaat
      181 agagaaaaaa aagtcatcgc tttatctgtc agtataagtc tacttgtgta tactcatgtc
      241 ttaactacac tattgtgtag tgcattgatt gcttgtatga ttatagttcg tttgttttta
      301 agcaagcaaa taaaaaacga tataaaattt gtggtcgtga atttagtaaa ggctgttttt
      361 ttgacttgtg cattaactag ctatttttgg tatcctatgt tgcagcagat gaattatcaa
      421 gaaatacaca gtcccttcaa aacagatttg cagctagaag cactttctat ttcagatagt
      481 atcattcaag cgttaaataa cgatattaca acatacacta tggggttatt aggattggtt
      541 gcgttgattt ttcctttatt catactgaaa gaaatggaga aaaaagaaaa aatcatctat
      601 gttggcgtag tttctacatg ggtatgcgta actaatttat ttccatggtt tttgtttcaa
      661 aaaacaccga taagcttgct ccagtttcct tggcgtatct taggtatcca aatctttttt
      721 tcttcaatga tcataacgct tgtttttatg aaaaagacta tgaataaaaa atattcatgg
      781 ttaatcattg gcgctactgt ggtgtttcta ctcgtcacgt ctatagcagc aaaagaaaat
      841 tacgcaaaag ttatccaatc aaaacacggt catattgtta tcaatgaaga aacactccca
      901 cgttatacaa catcagatat gggaggatta tacgattacg ccccaacaga agcgataaaa
      961 gaaaggcctc acttagaaaa acatgaagta aaagtaggag aatcgtggga aaaagggaag
     1021 tataaagctg cagataataa cattacttac acagtggcaa gcaacaaaaa gcaaaaagtg
     1081 acagtaccag tatatgctta tttaggtaca caggtaaaag taaacggtaa agtcgtaaat
     1141 gactcttata aaaaacatgg cttagtgaat gtggatgtaa atgctggaga aaataagata
     1201 gaaattacaa caaaatatac tccaactgct ctcatggctt tatggatcag tattctgact
     1261 tattgtttag tggtgtattc aagttttaaa cgatttgcac ctaataagtt gaaagattct
     1321 cgatatgtga ctaaaaagga gataaacaag aagaatgaaa ataaataaaa aagtagtaat
     1381 attgagtgga ttaattatag ttagtagtat atattctttc atctttttca aaaatacaca
     1441 gagtatttat accactggag atctttcttt tcacttatct cgaatcaagg ggttatcgac
     1501 tatttttacc agtccgatta attatgagac attcaattat actggatatg gtgtaaatta
     1561 tttttatccc tttctgactt tttttccagc tgtaatgtta tattggatga caaaaaattt
     1621 gattgtaagc tatattattt acgtttggtt attgaacttg tgtacaacac tcgtagctta
     1681 tcattatggc gagcggtttt taaaacaaaa aaaagcggca tttttattta gttgtctcta
     1741 tattttctct gcttatcgga cagtagacat ctactatcgt tccgcaattg ccgaagctat
     1801 cgcaataaca cttgttatcc ctgtattatt ttatgcttat caaatcatct ctggaaaaga
     1861 agaaaagtat ccgtctgtaa agctagcatt gagtatgagt ttgctagtgt acagccatgt
     1921 actatcaaca ttaatgagta cagcattaat tatcattttt atttttattc gtttggtttc
     1981 taaaggtttc aagaatgcag attttattgc tatatttaaa aaattattta gtgcggcagg
     2041 aatgacattg gttctgacga gtgctttttg gtatccgatg tttgaacaaa tgctctacca
     2101 aaaaatcaac aaacctagcg tgacaaattt atatgctcat gcatctaatg tgttcgatag
     2161 tctgactgaa gctatgaaca acgacttaac tacttactca atgggactag ttggtctgtt
     2221 atctttatgt attcccctga ttttatttaa aaaattaaca aacatagaaa aaaagattta
     2281 ttatggtacg tgtttgactt ggctagctac aactagtttg gtgccatggt atcttctgca
     2341 aaatacgcca gccaaattgt tacaatttcc ttggcggatc ttaagcttgc aaataatatt
     2401 ctcttctctg atattaacga tgatattttt caaaaataga agatacaata agacaagaga
     2461 actattttat ttatttatga ctgttttgtt attaatcact ttaactgttt ctagtaaaaa
     2521 aaatttcaat caaaaaataa tttctcagcc gggacatatt gttgtaaaca aagaaacagt
     2581 agaggcgtat accactaaag gaatggatta ttttttatat gattattctc ctatcgcttc
     2641 attggagaat aaggagcata taataaaaca cgaagcaaag attggcagtc aatgggtaaa
     2701 ccttccttat aaaacaactg gtagttctat catatataga gtaactaatg agaagagcca
     2761 agtaatcaca cttcctgtat atgcttattt aggaacgaat gtagaaataa atcatcaacc
     2821 tgtaaaggag caggtgaatg ctaatggatt ggtacaaata agcggagtca aaggagttgc
     2881 tgatattaaa gtaagcacaa gttatacagt aacgactatt atttcttatc ttgttacatt
     2941 aactgcatat ttatgtttat tttttaaaat agttttccat aaaaggtaaa ttaacttttc
     3001 atttataaaa taaattgatt aaaaaggaga atctgtcgat aaggattctc tcttttttat
     3061 acgaaaaatc tgtaggggga tgaagtaatc gcttatttcc tcactttatg ataaattaca
     3121 gctaaagtca ctagcttgtc ttcttcggaa aggaggagaa tctatggatg aggaacaaat
     3181 attcattcaa acactttata atctgatttt gaatccgaat acacgagatt gggaacgaaa
     3241 agtattgatt cagacaaaga atgacataag agaaaatata tccgttaaag aacagttatc
     3301 aaaactagaa gcaacactac gtccattagc tatccgaatg aatctgacgc ctgatgtaat
     3361 ggacttttat ttattgatta cggaaggatt tgataaggag caaaaatatg acttttccaa
     3421 gcatgccatg caagatgctg actatcaaga acgtgcagta tttgcagggg gatgtttctg
     3481 gtgtatggtc gagccgtttg aatcgaaaaa agggatccta tctgttttgt caggatacac
     3541 gggcggacat gttgaaaaac caaattatga tcaagtaagt ggtggttaca caggtcatgt
     3601 ggaagctgtg gagatcattt atgacacaag agaaataagt tatagcgagt tgctgacaat
     3661 ctattggcaa attactgatc ccacagatac atttggacaa tttcaagata gagggaagca
     3721 atatcgtcca gtgatttttt atcaaggcga acgacaaaaa gaattagcgg aacaatcaaa
     3781 acagaaacta gacagttcag gaactttcca ccaaccaatc gtcacaaaaa tcgaaccagc
     3841 cggtacgttt tggccagcag aaaactatca tcagcaattt tacaaaaaac aaccgaaacg
     3901 ttataaaaaa atccagcaag cacgtaatca atttctgatc tatcaacgag taaaaaacaa
     3961 atggcaaaaa aatatacgaa aaaatcattt tgattaactc cttttcttta aaatgtagta
     4021 aactaaaaat agaaaaaaga aagcgtttta aaaagatttg atgaggagga gaaaaattgt
     4081 atattgcaga tagtgcacgt tatgaaaaaa tggaatatcg taaatccggt cattcaggtt
     4141 tgaaattacc gattttatct ctcggattat ggcaaaattt tggtgattat gatcctatcc
     4201 ataatcaaag agagatttta agaggcgcat tcgacatggg aattacccat ttcgaccttg
     4261 cgaataatta tggaggccct gctggagctg cagagaaaaa ctttgggcgt atttttagag
     4321 aagattttca agcctaccgt gatgaactga ttatttctag caaagcaggt tatcatatgt
     4381 gggaagggcc atatggggaa tggggctctc gtaaatccat catttcaagt tgtgaccaaa
     4441 gtctccaaag aatggggcta gattatgttg acatcttcta tcatcatcgc ccagaccctg
     4501 atacaccttt ggaagaaaca gcagaagctt tgatgcaact tgtaagacaa ggaaaagcat
     4561 tatatattgg tatatccaac tataatggag aagatacaaa aaaaatgact gaaattttaa
     4621 aaagaaagga agcaccgttc attattcatc agatgcgcta caatatgttt tctcgtgcac
     4681 tactagaaga cgatctatct ccagtattag aagaagaagg gctaggggca atcacgttca
     4741 gtccgcttgc tcaagggttg ctgacaaatc gttatctaca tggtattcct gaagattcta
     4801 gagcacatcg taaggaaata ccattccttt cagaagaaca agttggatca actctggaaa
     4861 aaatcaaagc actgcaaaca atcgccgtat cacgaggaca atcattagcg caaatggccc
     4921 ttgcatggaa tttgcgacaa aaatctgtta caagtgtact ggtcggagca agtcggttaa
     4981 gtcagttaca agaaagtgtt cgaatgatgg ataatttaga tttctcacca gaagaagaat
     5041 tgagaatcga ccaaattcta gaatagaaac gatgtaatca aactttttat ccatatatta
     5101 aaaaaaacaa aagatgacat caagaatcga atgaagatcg tctgttattg aacatcatat
     5161 tttttgtcgt tcaaaataaa aatgatcgaa ggctaggagt gaatttt
//
LOCUS       DADGHT010000138         5087 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.141, whole genome shotgun sequence.
ACCESSION   DADGHT010000138 DADGHT010000000
VERSION     DADGHT010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.141"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="JX887_002638"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="JX887_002638"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HAX1258565.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="JX887_002639"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="JX887_002639"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HAX1258566.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="JX887_002640"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="JX887_002640"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018593001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HAX1258567.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="JX887_002641"
     CDS             complement(4028..5044)
                     /locus_tag="JX887_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAX1258568.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
BASE COUNT         1337 a         1270 c          909 g         1571 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaa
//
LOCUS       DADGHT010000139         4956 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.142, whole genome shotgun sequence.
ACCESSION   DADGHT010000139 DADGHT010000000
VERSION     DADGHT010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.142"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(55..828)
                     /locus_tag="JX887_002642"
     CDS             complement(55..828)
                     /locus_tag="JX887_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAX1258569.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            972..1322
                     /locus_tag="JX887_002643"
     CDS             972..1322
                     /locus_tag="JX887_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAX1258570.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            1303..2019
                     /locus_tag="JX887_002644"
     CDS             1303..2019
                     /locus_tag="JX887_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1258571.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2019..3467
                     /locus_tag="JX887_002645"
     CDS             2019..3467
                     /locus_tag="JX887_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1258572.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(3537..4046)
                     /locus_tag="JX887_002646"
     CDS             complement(3537..4046)
                     /locus_tag="JX887_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258573.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4036..4761)
                     /locus_tag="JX887_002647"
     CDS             complement(4036..4761)
                     /locus_tag="JX887_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258574.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         1703 a          843 c          998 g         1412 t
ORIGIN      
        1 ttaagaaaaa ataagcgatt ttcttaagaa aagaggtagc ttcaaaaaaa gatcttaaat
       61 cagatcaaaa tacttcaatg cgtggacaat tccgccttct gtatttttct ttgtgataaa
      121 ggtagaaagt tcttttaatc cgtcataggc gttgtccata gcgattttgt tgtcgcaagc
      181 ttccaacaag gcaaaatcat tcggaccatc gccaaatcca aaagtaggaa ctttttccag
      241 ctgaagttct ttttgcagac gtttgacacc tgcccctttt gagattcctt tcttcactgt
      301 atcgatcgag taaggaccat tccgataaaa agttagctca ggaaaatgtt cgtgatagta
      361 ttcgtcacct gattgagata agatcagcaa catatttact gtgttttctt taaagcctaa
      421 aggatcaatt tccggaacat ctgaatgaat gaagtcgtaa gcattgatca ttgtttggct
      481 atgaccggta caccagattt tctgatcgtt atagtaagaa agttcatgac cgttcaactg
      541 tacatgatca tacatttttt gacattcttc tgaagaaaat gtttgagaat agatttcttc
      601 gccgtctact cgaatgaaag aaccattcat ggtgaccgca gaagtaatgc ccgcatcttc
      661 catgatagag tggatttctg cttctgtacg tcctgtagcg atgacgggga gaacattgtt
      721 ttcttttaat gcgttcatag cttttgccac ttcgggtgtg atttttgatt tcgcatctag
      781 taatgttcca tcaagatcaa agaaagtgat tgcacgataa tttgacacaa ataaaactcc
      841 ttttttattg gaataagttt atcttaacaa agaatgaaca aaagacaaac ctttcgtgaa
      901 gaattcctga acatattggt tcagtcaaca atttagagta tactataaga agagaattta
      961 ggagggaaag aatgattttt ttcagtattg gtatcttatt cttaataatt ggcagtcttt
     1021 ttcggattct gccctcaaaa ggaaatctgc ctttttatgg gtatcattcg cctcttgccg
     1081 caaaaacaga cgctcattgg cggctggctc aaaagacaag cggaaactgg ttttttctta
     1141 tgggcttact gatggcattg atcggctatt atttaaagac atctgggcat acgaattatt
     1201 ttctgattga aatgcttctg ctagtatttc caattatgcc tatttttatt atgacagaaa
     1261 agaaattaca gaaatatgac ctggaaactg gagggaacga taatgaatat tttaatgatt
     1321 gaagataatc aatctgtttc tgaaatgatg cagatgtttt tcttaaatga aggttgggaa
     1381 gcaactttca agtatgatgg aaaagaaggg ctcgatgcct ttttagaaaa cccacaacat
     1441 tgggatatga ttacactaga cctgaatttg cccacactgg acggtatgct agtaggaaga
     1501 gagatccgca aagtttcaag tactgtgccg attatcatgc tgacagctag agattctgaa
     1561 agcgatcagg tgatcggctt agagatgggg gcagatgatt atgtcacaaa acctttcagt
     1621 cctctgacgc ttattgctcg aatgaaagct ttgcatcgcc gtagtgagtt ggcagaagca
     1681 agagaagaag cagcagtttc agatgatcat tttgatatcg agactagtca tttcaagatg
     1741 aatacgaaaa cacgagaagc gtatctggac aaccggccaa ttgaaggact gacgcctaaa
     1801 gagttcgatc tattgtttac tttagcaaaa aaaccacgtc aagtattctc tcgggagcag
     1861 ttgcttgaat tagtctggga ttatcagtac tttggtgatg aacggacagt ggacgcccat
     1921 atcaagaaat tacgacaaaa aatcgaaaag gtcggaccac aagtcatcca aactgtttgg
     1981 ggagtcggct acaaattcga tgattctggt gttgcctaat gcgttatttg tatcagcaac
     2041 tcttagcttt ttgcggaatg gtcgcgttga tcttattgat cgttggagtt tcttttacac
     2101 aactgacaaa acaaacgatt gaagaaaaca attaccagca actgtttgga tatgctgaat
     2161 cagttgaaaa gacaacgcaa acctatgccg atacgctccc gcagtttagt caagatcagg
     2221 cgtttcaaaa tgcattgctg ctgacagagc aagtactgac agaacaaaat gtgaacttta
     2281 tatttatcga taaaaacgaa cgtgtcattt atccgactaa tacagcttta ctgaatttta
     2341 ccttaacagc tgatcaatgg aaaaatctga ggaatggacg tcaagaaaaa ttcacatcga
     2401 ataaaaatat tttaggacaa gcacaggcga cctcttacgc acttgtgcca tttaatttga
     2461 atcatgaatt ctatggagca cttgtagtta gtcaacctgc gcgaaatatc gataacagcg
     2521 ttcgtccaat tacactgaac ctgttcaaag gatttatttt ttccagtatc gttgcagtta
     2581 ttgccagcta tgcttttgca gcattccaag ttaagcgtat caatcggtta aggaatgcga
     2641 cgaaagaagt gacgaatggt aattttgatg tacagctccc cgtacatgac aaagatgaat
     2701 ttgatgagtt agcagatgat ttcaataaaa tgacgaattc attgaaagaa tctcaagcag
     2761 aaattgaaga acaagaaaat cgtcgaagac aatttatggc agatgcttct cacgagatga
     2821 gaacacctct tacgacaatc aacggacttc tggaagggtt agaatacaat gcaatccctg
     2881 aaaatcagcg agaaaacgcg attaaattga tgaaaaatga aacagagcgt ctgatccgtt
     2941 tggtgaatga aaacttggat tatgaaaaaa tccgtacgaa tcaaatcagt atggtcatta
     3001 aaaaattcaa tggaacagaa acattgaaaa atattgttgc acagttagaa gctaaagcag
     3061 aagcagcagg agatacattg acattgaaag ccgttgatga tattgatgtt tacgctgatt
     3121 atgaccgatt tgtccaaatc atggtcaata ttattcaaaa cgcgatacag tttactgaaa
     3181 acggccaaat cacgattact ttagaaaaag gctatcttga aacgatcatc acgattgaag
     3241 atacgggaat tggaatgtct gaacaacaaa tgaaaagtat ctgggatcgt tattataaag
     3301 tagatccttc aagaaaaaat acaaaatatg gtgaatcagg attaggttta ccaatcgtgc
     3361 agcaacttgt acgcttgcat aaaggaaaat tagaagtaga aagcgaacta ggaaaaggaa
     3421 caaaattcgc tgttcgtttg cctgacgtag aaatcaaaaa agagtaaaaa acaagcggta
     3481 taaaagatca tgaatcgatc ttctataccg cttgttttta ctataaaatg attgatttag
     3541 cccgcgggct ctaaacgatc aatataagga ctttgagcaa tagtagcatc atgagtaaag
     3601 agtaagatac cttgattttc ttcatgagct aaataagaaa gcaagtggag tagctcttgg
     3661 atctccaata cactaagttc atcaaatgta tcttcaataa caatattgtt tcgcttggaa
     3721 agcaaggcat gaagtaattg cagctttact ttttcaaaag acgtcaactc agctgccgca
     3781 caattaagca aggaaggaga gatatcaagt ttttcttgat aggccaaacg atcttgtttg
     3841 atttcttttt ccggtacatc caacaggaca tggtctttaa gattcagata aggaaacatc
     3901 ggccaatttt tttggatgat cgcaaaatta tccagttttg caacaagaac ctcttttttc
     3961 aagtgctcca atattttatg ctgtttttcg agaggacaca aaataacggt caagtgttca
     4021 gcatgaatca aatattcagg tttcattacg tccaggcctc ctactttgca aatgatggat
     4081 aaaaaaagtg aaagggaata gactaagaat gagacagcat ccactgagcc caataagagt
     4141 ttgggcaaat cccttaagta tatctgtgaa aaaaagatca ttttggaaat cgatggtaaa
     4201 aaaagtctgt tgatccatcg gaattgtaag tccgcttacc gaagtcaaga tatcacggat
     4261 atctggcagt tcagtagtct ttaagacaag aaaattgatc ctttgaagaa gcgcttcata
     4321 aactgactgg aagctgacga tccacaataa aaccaagata caacaaagaa agagaggaaa
     4381 gaacagctgc cagaaaataa aaaggaataa tttggtttta gaaagaccag tcaggcgcca
     4441 attgatcaat tcctgcttgt tttgcctgac tgaatagtaa aagaaaaaga taaaaaggaa
     4501 ggcaaataga aaaaataaac tgaatatgcc ttttatataa aatcggctag ctaattctaa
     4561 agccggaaga agctctgtag atgcagaagc gccaataaat gaaagccgat cttggacttg
     4621 attggctaaa gccgattgcg aatggtaaag agtcaggcat gctatcaata aaaaagcaga
     4681 aaagcttgaa aataaacaat agagtattgt ctgctttttg taataaatta atcgagcagt
     4741 agcatagcgg attattttca tacttttcac ctctataaaa agtatagaaa atgaatatga
     4801 ataaagtatg aaattccttt agtgaaatca cgaattaaaa ccagaaaata ttttgtaaaa
     4861 agcaagaggt tgtgaagaag ctgccctatt ctattaccgt agatgcaagc ttttgaacac
     4921 tgtttattcg aaaagaggag cagcgacaat aatttt
//
LOCUS       DADGHT010000140         4861 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.143, whole genome shotgun sequence.
ACCESSION   DADGHT010000140 DADGHT010000000
VERSION     DADGHT010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.143"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..750
                     /locus_tag="JX887_002648"
     CDS             <1..750
                     /locus_tag="JX887_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1258575.1"
                     /translation="FESLYNCAIAENADIAIGEVGIFSDREIERVKIRKSLTNLKTIE
                     LATYNKKEFFKQFYFNRLYSHNAWDKIYRRSLVLEFNLSFGDNKIIFAEDNWFQLQVF
                     MTNTRICFVDKLCYYYRQQNNSIMHKPKSNLVFRHGNMIADYEKLIRQNGNNIIDKKA
                     CMLVAFDVLIMEIFNQKNVGGTCEDYKNALVSLKHHKILRENISNIVRMKAYELEPNM
                     RKKLALVTISIMFNFKMYKTAYNMLWRIYNR"
     gene            764..1843
                     /locus_tag="JX887_002649"
     CDS             764..1843
                     /locus_tag="JX887_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAX1258576.1"
                     /translation="MRKLTFVIGIMGKGGAERVIANLANNFIQDNWEIDIITIYGNRQ
                     DYELNRKIQVHPIICKSSFRAFRPLERFKELRKKIREIQPDLVISFLADVNIHVIISL
                     LGVKQKLIVSERNDPQRNPEEPWIRKIRDFLYKNVDGIVFQTPDAKKYFSKINDKKVK
                     TIIIPNPIKENLPYYNKTTSSKKFITACRLDKQKNLPLMIDAIGKLIHEGYECELDIY
                     GEGGLKTELESYINHNGLTEFVHLKEFTNKIHEKMQNAAGFVISSDYEGISNSMLEAL
                     AIGVPVIATDCPVGGARMYLGDRNEIGHLVECNNLDKLTDAMRRVLLDRESVVRKAQK
                     GIKLRKELTSKNISNIWYEYLNQFF"
     gene            1886..3286
                     /locus_tag="JX887_002650"
     CDS             1886..3286
                     /locus_tag="JX887_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy"
                     /protein_id="HAX1258577.1"
                     /translation="MFSLTLVAFTIFCAFSLNQNYWLNWLGILIYLYAICTWHWRKGD
                     SIFSLYTIFFTLFLLFSYGQCIMWAFGIGTDRGIGTTVVAYGTGIIPSESDMIMVKWY
                     SCISMFVFHIGALLFTRKTTLRKVSWYESGDADADRKFLFKIGCIISIIVVPIVFVSK
                     LLEVRIALVHGYNALYYGDYATQSGYLQIILYLFFPALICLLIGSNFSKVITRFVFII
                     FALYSLLGIMSGDRGSWLYSSIILIWAYTQYKGTFNYKKLIKWLILAVIGIYILNVIT
                     KARDGGGLSKLTLKDFTSVFDSDDSPLVDSFFEMGGTMSIITFFLISGNGIYPFANTY
                     LTSLLGSISTRMLSMFGIKFVLLADWFSQDYLGITWGTGFSMIAEAYVNGGYIGGIVY
                     IFIIGIVIGKILSNSIDNQDIENHPMKMFLAITTANIIMGFPRAASYLIVKNFVYGVL
                     IILLINFFLQQFNKRL"
     gene            3332..4837
                     /locus_tag="JX887_002651"
     CDS             3332..4837
                     /locus_tag="JX887_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar isomerase"
                     /protein_id="HAX1258578.1"
                     /translation="MERTARLKKNTIWALVFQITSIVCGMILLRLILTKYGSEVNGMI
                     SSINQFLQIISFLQLGVGAVMQSTLYKPLAEKDNLMISQILASGGKFYRQIAYILLVY
                     VGLLLAVYYVLVPNEFGRSYTMAMIATLSINSFAQYYFGIVNTLLLSADQKIYITYIA
                     QTIAFISNTVACALLISLNTEILMVKLITAIIYLACPIYYRWYVDRNYNIKRNVSYDK
                     EPIPQKWNGVAQHVASVVLDSTDVVVLSIFSNLIYVSIYNVYNLVIYGVKQLFMAMTN
                     GVQALLGELWVRKEIEVLYKTFAWFEWIVHTLTVFIFGCTGILIVPFIQVYTRGVTDA
                     NYNQLSFAALLVTANALHCLRTPYHVMIKAAGKYKETQNSFIIASLLNLGLSLILVKP
                     LGLVGVALGSLISITYHTLWSANYNSKYLLKWPMKKFYKQLFVNILTVVLSFGATSQL
                     KMMSITYLDWIVLAIKCAVIVFICIILVNVLFYRRYVVKIISKIIVKIKKI"
BASE COUNT         1726 a          584 c          869 g         1682 t
ORIGIN      
        1 tttgaaagtt tatataattg tgcaattgca gagaatgcgg acattgcaat tggagaagta
       61 ggcatttttt ctgatagaga aatagaaaga gtaaaaataa gaaaaagtct aacgaactta
      121 aaaacaattg aattagcaac atataacaag aaagaatttt ttaagcaatt ctatttcaat
      181 cgtttatatt cacataatgc ttgggataag atatatagac gtagtttagt attagagttt
      241 aatttatcat ttggtgataa caaaataatt tttgcagaag ataattggtt tcaattacaa
      301 gtatttatga caaatacaag aatctgtttc gtagataaat tgtgttatta ttatcgccaa
      361 caaaataatt ctataatgca taagccaaaa agtaatttgg tttttagaca tggaaatatg
      421 attgctgatt atgaaaagtt gataaggcaa aatggaaaca acataataga taaaaaagct
      481 tgtatgttgg ttgcatttga tgtactaatt atggagattt ttaatcaaaa aaacgttggt
      541 ggaacatgtg aagattataa gaatgcatta gtttctttga aacatcataa aatattgaga
      601 gaaaatattt caaatatagt tagaatgaaa gcatatgaac ttgaacctaa tatgagaaag
      661 aagttagccc ttgtgaccat tagtataatg tttaatttta aaatgtataa aacagcgtat
      721 aatatgctct ggagaatata taatcgataa agaggtagga aatatgagga aattgacctt
      781 tgtgatagga attatgggaa aaggaggggc agaacgagta attgcgaatt tggcaaataa
      841 ttttattcaa gataactggg aaattgatat tataactata tatgggaatc ggcaagacta
      901 tgaactgaat agaaaaatac aggtacatcc aataatatgt aaaagttcgt ttcgtgcatt
      961 tagacctttg gaacgcttta aggaacttag gaaaaaaata agggaaatac agcctgatct
     1021 ggttatttcg ttccttgctg atgtaaatat ccatgtcatt atttcattgt taggagtaaa
     1081 acaaaaatta attgtttctg aacgaaatga tccacaacgg aatccagaag aaccatggat
     1141 taggaaaatt agagattttc tttataaaaa tgtagatgga attgtttttc aaacaccaga
     1201 cgcaaaaaaa tattttagta agatcaatga taaaaaagta aaaacaatta taattcccaa
     1261 cccaataaag gaaaatttac cttattataa taaaactaca agtagtaaaa aatttattac
     1321 tgcatgtaga ttggataaac aaaaaaattt gcccttaatg attgatgcaa taggaaaact
     1381 tattcatgaa ggatatgagt gtgaactgga tatttatgga gaagggggat taaaaaccga
     1441 gcttgaaagt tatatcaacc ataatggatt aacagaattt gttcatctaa aagaatttac
     1501 aaataaaata catgaaaaga tgcaaaatgc ggcaggattt gtaatttctt ctgattatga
     1561 aggtatatct aattctatgt tagaagcact ggctattgga gtgccagtta tcgctacaga
     1621 ttgtccagta ggtggcgcaa gaatgtattt aggtgataga aatgaaatag gtcatcttgt
     1681 tgaatgtaat aatctagata agttaacaga tgcaatgcgt agggtacttt tggatagaga
     1741 aagtgtggta agaaaagcgc aaaaaggaat taaactaaga aaagaactga catctaaaaa
     1801 tatttcaaat atatggtacg aatatttaaa ccagttcttt taaccaaaag gaggatattg
     1861 tgtgaaagaa aaaataaata tattgatgtt ttcgttaacg ttagtcgcgt ttacaatatt
     1921 ttgcgctttt tcattaaatc agaactattg gctaaattgg cttggaatat tgatttactt
     1981 atatgcaatc tgtacatggc attggagaaa aggagattca atattttcat tatacacgat
     2041 ttttttcact ctttttttat tatttagtta tgggcaatgc attatgtggg cattcggtat
     2101 tggaacagat cgtggaatcg gtacaacagt agtagcttat ggtacgggga ttattcctag
     2161 tgaatcagat atgataatgg taaaatggta ttcttgtatt tctatgtttg tatttcacat
     2221 aggagcactc ttatttacga gaaaaaccac actaagaaaa gttagttggt atgaatctgg
     2281 agatgctgat gccgatagaa agtttttatt taaaataggg tgtatcattt ctataatagt
     2341 agtaccgata gtttttgttt ctaaattact agaggtacgt atagcattag tccatggtta
     2401 taatgcatta tattatggtg attatgctac acaaagtgga tatttacaaa ttattctata
     2461 tctttttttt ccagccttaa tatgtttatt aattggtagc aacttttcaa aagtaataac
     2521 gagatttgtt tttattattt ttgctttata ttctttatta ggaattatgt caggagacag
     2581 aggaagttgg ttgtatagct ctattatact catatgggca tacactcaat ataaaggaac
     2641 ctttaattat aaaaaattaa taaagtggct tattttagct gttataggaa tatatattct
     2701 aaacgtaata acgaaagcac gtgatggtgg aggactaagt aaacttactt taaaagattt
     2761 tacatctgta tttgattcag atgattctcc tttagttgat tctttttttg aaatgggggg
     2821 gactatgagt attataactt ttttcctaat aagtggtaat ggaatatatc cctttgctaa
     2881 tacttatttg acctcactct taggctctat atcaacaaga atgctatcaa tgtttggaat
     2941 aaagtttgtt ttattagctg attggttttc tcaggattat ttaggaatca cttgggggac
     3001 tggattctca atgattgcag aagcctatgt caatggtgga tacattgggg gtatagtcta
     3061 tatttttatt attggtatag tcatcggtaa aatcctttct aatagtatag acaaccaaga
     3121 tattgaaaat catcctatga agatgttttt ggctataact acagcaaata ttataatggg
     3181 ttttcctaga gctgcttcat atttaattgt gaaaaatttt gtgtatggtg ttttaattat
     3241 attgttgata aactttttcc tacagcaatt taataaacgt ctttaatatt taagcttaat
     3301 aaaaagataa aacaagtcag gagttgcaaa aatggaaaga actgctcggc tcaaaaaaaa
     3361 cactatttgg gctctggtgt ttcaaataac ttctattgtc tgtggtatga tcttgctacg
     3421 tttgatatta acaaagtacg gatccgaggt taatggaatg attagctcta ttaaccaatt
     3481 tctacaaatt atttcttttt tacaattagg agtaggcgct gtaatgcaat caactctata
     3541 caaaccacta gcagaaaagg ataatttaat gataagtcaa atcttagctt ctggagggaa
     3601 gttttatcgg caaattgcat atattctact agtatacgtg ggtttgttac ttgcagtcta
     3661 ttatgttctc gttcctaatg aatttgggag atcatataca atggcaatga ttgcaacatt
     3721 aagtattaat tcatttgctc aatattattt tggtattgtt aatactttgt tattaagtgc
     3781 tgaccagaaa atttatatta cgtatattgc acagacaata gcatttattt ctaatacagt
     3841 tgcatgtgct ttattaatta gtctgaacac agagatcctt atggtaaaac ttattactgc
     3901 tataatttat cttgcttgtc caatatatta tagatggtat gtggatcgaa actataatat
     3961 aaagaggaat gtgtcatatg ataaggaacc gatccctcaa aaatggaatg gggttgcaca
     4021 acacgtagct tctgttgtac tagatagtac tgatgttgta gtgttatcta tattttctaa
     4081 cctgatatat gtatctatat ataatgtgta caatttagta atatacggag taaaacagct
     4141 attcatggct atgacaaatg gcgttcaggc cttactaggg gaactttggg tcagaaaaga
     4201 aatagaagtt ctttacaaaa catttgcatg gttcgaatgg attgtacata ctttgacagt
     4261 ttttattttt ggctgtaccg gtatactaat cgttccattt attcaagtat atacaagagg
     4321 agtaacagat gctaattata atcaattatc attcgcagct ttacttgtaa ctgctaacgc
     4381 acttcactgt ctgcgtacac cttatcatgt aatgataaaa gcagctggta aatataaaga
     4441 aactcaaaat agttttataa ttgcttcttt gttaaattta ggtttatcat taattttggt
     4501 taaaccacta gggctagttg gagtagcatt aggatctcta atttcaatca catatcatac
     4561 actttggagt gcaaattata attcaaaata tttgcttaaa tggccgatga aaaaattcta
     4621 taaacagtta tttgtaaaca tcttaactgt agttctttct tttggggcga catcacaatt
     4681 gaaaatgatg tcaatcacat atttggattg gattgttctc gcaattaaat gtgcagttat
     4741 tgtatttata tgtataatcc tagttaatgt tttattttat agaagatatg tagtaaaaat
     4801 aattagtaaa atcatcgtaa aaataaagaa aatttaatac acaataaatg ttttaataaa
     4861 c
//
LOCUS       DADGHT010000141         4808 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.144, whole genome shotgun sequence.
ACCESSION   DADGHT010000141 DADGHT010000000
VERSION     DADGHT010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.144"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(90..1175)
                     /gene="xerS"
                     /locus_tag="JX887_002652"
     CDS             complement(90..1175)
                     /gene="xerS"
                     /locus_tag="JX887_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAX1258579.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3251..3769)
                     /locus_tag="JX887_002653"
     CDS             complement(3251..3769)
                     /locus_tag="JX887_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HAX1258580.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1580 a          786 c          729 g         1713 t
ORIGIN      
        1 ataaaaatga taatgaagct tgcctttaaa gttgggcttt tatctaattt tagagacagg
       61 cttcattatt atactatttt ttactacatt tacaaagcgt tcaaagcatc aattgtagct
      121 gcattgtcta tatgagtata taaagttgtt gtatttgtac ttgtatgtcc caattgttgg
      181 gcagttaata ccaatgaatt tgtctgttga tagagtctag tagccaaagt atgacgtaat
      241 ttatgtggac tgacttggac tctgaatcct tttgaatatt ttgctaccat ccgttcgatt
      301 gcaataccgg atatacgctt ggcttctcct tgataaattg ctagaaataa agctttttcg
      361 ttttctgtta ctttgtatcg ttctttccga atagctagat aattagctaa atattccatt
      421 gcaaatgctg ctatatttac tgcgtctctc ttatttcctt ttctagttac taccacatta
      481 ttcttttcta aagataggtc ctctaaatta atatttacaa cctcggagag tcttaatcca
      541 gatcctaaaa tcaatgcatt gatcgccagg tctctttcta catctcgttg ataatagatc
      601 aaagctcgtt tgctcaaagt ttttttatat tcattggcaa tataatctag ataattttgt
      661 gtatcttcgt ctagaaataa ttttttctcg attgcgtttg cacgggcagc taacgtagtt
      721 ttatctgtga tagttgctac ttgatccata ggattatttt ctaagtatgg ttttcctaaa
      781 ggattattgg aacttttcga aagatattta aatagaacct ttaatgctgt gatatttcta
      841 ttgatagtag aagtagatag acctaagtta ttattatctt tgagcttagt ttttgttgtc
      901 tcttttttta cattttcctt tgtgcgacgt ttcaaatgag atttgtacaa gtttagatca
      961 taggcagtta actgtcttat cgaggtgatt gaagtatcgg gaacgataga ctcactcaga
     1021 agccattcat aaaagagctt ataatttttt agatattcta aagtagttcg aggtgattga
     1081 tctttatcct cacgatcttg aacaaaatct tttatataat cgggcatatg aagtatgatt
     1141 gtatctattt tttgatatat ttctgtattt ttcatgttat tcatcctttc gataagtagg
     1201 ggagaggagt atctctataa ttggactata ccaattatag agtgttttgt caattggtat
     1261 actctgaaat ttattaattt atttcaaaaa agcagataaa taggtataga tttaataatt
     1321 taaaataaat ggtatacatg aataggaaag gaaacagaag gaggcaatct taatttttta
     1381 aattgtctaa attatataga aagaacaatc tttctatata attagacata agagagacta
     1441 cggttgattt gatattaaca agcgtatatg aatgtatata caaataaaaa aggggaggga
     1501 gaagttaaag aaaattcaga gaagtggggc actcagtagt attaacaatt taaaaggaat
     1561 ttcttaaaga aaatgggttg catcctggag atacaatttt tttagataaa gaaaaaattc
     1621 aagcaacaat tcaaaaaaat cttaactgct gagattgatg tagcaatatc tcaatcatca
     1681 acaaagtacg atcctgcctt tcaaaagctt attgataaat gtttattcat tataaaaata
     1741 aaagaaaaat ttatgtcagc ttttttcatc aaagtggtaa tgataattcg tctattaatt
     1801 gtatttttta ggaaatatgg tataattgtt ttaacgaaaa ggtaattcat gatacaccaa
     1861 aaaccactag ctggcgggct agtggttttc ttttacgttc tattcagatt aacgggtagg
     1921 cttactgtct tttttggcaa taattttgca atcaagccat ttacagatgt aatgcgcgga
     1981 tacttctgct aagattgcaa aaaacatatc gaaaaggtaa ttcataatac aacctcctcc
     2041 ccttgccata ataggccggg gtagcagaca gcataaatat tataccataa ctgaaaattt
     2101 cattttagta catttcaata tattgatgaa ccagcacaat aaaacatgcc atgactaaca
     2161 gaaaaaaact tattaaacca gatataactt gtaaacatcc aactatatag aaaacgtaaa
     2221 ttttctatat agttggatta agataacgac tatttatttt atcatatttt tactataccc
     2281 tatactttta cttggtatat ttatgaataa tcgcaaattt acccctatac tactagtttg
     2341 taagttagat taataaaaat actaaagtta tttgttcttt tattaaatac acctacaact
     2401 tataaattga tggtatttag ataacacgaa agaataaaaa taacagctga tagtaaagtt
     2461 tgttgacgat tgctactcaa tcgaaagtga gttagtgcgt atgaacttgc ttctgaaaac
     2521 ttatgaaatg aaagaccttt tacatcttgc agaaatcgtt actgggatta aactaagcaa
     2581 taaaaactaa tgttcccctc attctttgaa cttctactat ttgatttatt tattctgata
     2641 aatgacgatt tcaccttcag gatcttcaaa tcccgtatag aatttattta agatctcttc
     2701 agtatcagta ataggatagg cgataggcca catacccttt gatggttaga ataaactgct
     2761 caaaatctgt atcgtatgtt ggctttagca tattaacaaa ggctatctcc aaattataaa
     2821 ccataagcgt tgaatcgttc ttaacaattt caattcttcc taacccaaag tcagaagata
     2881 taattaccgg acttgcctta cccttcatgt gggttgttga gattccatat ttaaagggaa
     2941 ttgtcggtac tatcggcggt ctgaaaaaca tcccaaaaat aaaaaaatct ttcccctgct
     3001 agtctcctaa gtccctttgt agcggatatg gcaccataat ctcattttat cgaagtgagt
     3061 catggtttat ctgttggcca accaaaattg atacaatcta acgatgcacc ctctacggca
     3121 ttctagggga gtgcacttgc attcacccaa taaaaaccgg cagttagcaa agaacttatg
     3181 tagtcgtatg ttcttactgt taacatacaa gaggtctcct ttccacaatt gcttagcagt
     3241 aaacgggaat ttacaaagct aatctcttcc attttcttat ctttgttcta aaagtcccaa
     3301 atggagcaac tgtatttaca tgaataaatt tatatacttc ccatacagcc gttttggttg
     3361 cctcgtctgc ccattttctt ttgtgtgcag tgaatagatc ttcatcactc attgaatcaa
     3421 tcatcatgtt aatatcatca atattacgat tgagaatttc ctctaattct ttcaatggta
     3481 gatgtgcata ggtatttgta aaccacttat ataactctcc taactgattc catttaaatt
     3541 gatcagaagg cgttttaaca gataatccat ttctttcatc attttcccat tttagaatta
     3601 aattcgtcca accaacttga tatgctaaat tttcagcagg tgttctatcc acttcctcaa
     3661 ctcttttatc cttcaattct tcaggaatag tttcaaattc taaaatatat ttagtataag
     3721 tcctatttat ttcttttttt aattcttctt tatttttata tgttctcatt atattacctc
     3781 cataaattcc taattgtctc ctttaattca tctataattt catccacgat attttaatcc
     3841 gttctacaat gcatatctga tatgcattga ctgtctaact catatgtgaa tgatttataa
     3901 aatatcccaa cgtctcatct aaagaaatgt tgatcgtcag caaggagcta aaaaatacga
     3961 atatatttct tttgtagtaa aatcggactg gtttgcatat cattttcttc gtaaatatca
     4021 aaatcatgtt aactactatc aattactaat aaaaactacc actttaagcg ttaagaactg
     4081 ttaagtttag ttaagtgagg atagttcaca aaatccattg ttaaacttca cgaaagtggt
     4141 aaaactcaaa atgctttata taggattaca gcatcgctct ttcttcgatt gcgcgttggg
     4201 taaaaaatat tatgaagtaa aaattgacga tgacacgttc cttacggctc atcagatgaa
     4261 acagctacaa aaacgaaatg atcaactcga agaaaattta attctaaaaa agcgattgcc
     4321 atattcacgc ctcgctcgac gaactattaa aggtcaagat ttacctgaag atcatccttt
     4381 ttaggaaatt gaagcttttt atgttgcaca atgcatttat aatactacaa tgatgttttc
     4441 accagatatt cttctagggt gcggtgtaat gaaacagata cacttgcaaa agaaaattca
     4501 ccgcgaattt actaaaatta tgaataatta tgttaatctt ccgaaatttt tttccaaaat
     4561 taagggatca agctggtgtt atagattgtt taaggttggc aaaaaaataa cttcttttta
     4621 aacaattata gaaaaccgat actctgttaa gttggttgac acggtgtcga tttttatgac
     4681 tttcttattc tgaaacttca ctaacggaca gtacctaaaa agtctatagt atggacgttt
     4741 acgagtacta ttttatcaaa aatgctgctc atttcaactt atatgtttta gtgaactacc
     4801 cccactta
//
LOCUS       DADGHT010000142         4744 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.145, whole genome shotgun sequence.
ACCESSION   DADGHT010000142 DADGHT010000000
VERSION     DADGHT010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.145"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            25..696
                     /locus_tag="JX887_002654"
     CDS             25..696
                     /locus_tag="JX887_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAX1258581.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            755..1195
                     /locus_tag="JX887_002655"
     CDS             755..1195
                     /locus_tag="JX887_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258582.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1207..1875
                     /locus_tag="JX887_002656"
     CDS             1207..1875
                     /locus_tag="JX887_002656"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAX1258583.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1939..2562
                     /locus_tag="JX887_002657"
     CDS             1939..2562
                     /locus_tag="JX887_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAX1258584.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2618..3004
                     /locus_tag="JX887_002658"
     CDS             2618..3004
                     /locus_tag="JX887_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAX1258585.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3217..4608
                     /locus_tag="JX887_002659"
     CDS             3217..4608
                     /locus_tag="JX887_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAX1258586.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         1580 a          782 c         1011 g         1371 t
ORIGIN      
        1 aatgatgaaa aaagggggag aaaaatgaat tttttagttg ttttaaaaga tactctgatt
       61 gagcgatcta catttctata tgttcaattg caggaaaata aaacattgct gcatttttca
      121 ccagagttcc atctagaggg gctaacatta ggagaaatct atcaagcaga agggctgtcg
      181 gctgttttgc acttttttaa ggtagaattg gaattaccag taaaagatta tatcgagctt
      241 tctcttgaat cttgggatcg agcagtggtt gaactgtttc cagaaggttt aatgatcgat
      301 acaaacgatg ggaagatcca tctgactgca gcagaactgc aaaaacaaat gcgttatcaa
      361 atagatgacg aaaattcttt ttctattttt agacgtcagc aaaagattct aaaaagcttt
      421 ttaaaagtga tcagtaaaaa acggaatctg atcaaaacga cacagctgtt gaaaaaatat
      481 ccaggtctgc ttcacacgtc tattcaattt cctcaattga ttacgatgat ccatcgtttt
      541 atacgtatgc aacagctacc atctaagaag ctgtttcttc cattgacgga cacatttcga
      601 gtagtcaaca gagaagataa aaagaaagtg attgtgattg actttaccag aaatcggaat
      661 gtccttcacc aagttgcaat ggaaaaggcc aattaaggct ttttcttttt ggattttttt
      721 gtcataataa atattagatg atggaggaga taatatgatg caaacatggt tagaaaggct
      781 aatacgattt cagcagaact atcacaaact tatgcaggga agatatgcga aatttgatca
      841 gttgaatcgc ggtctattga tcgctgcgct tgtctttagt ttgctaagtc gttggttgcc
      901 ctatagaatc ggacaattgt tgttcatcgt ctttttcgga tggatgatat ttcgtttcct
      961 atcaaaaaaa atctacccca gactaaatga gaatcaacgt tatttgaaat atcttgatag
     1021 agtcaaagaa aaatatcatc agataaaaaa caaaaagcaa gtcaaaatgg atcgaaaaag
     1081 ttatactttt tttgagtgcc cgaattgtca tcaaaagcag cgtgcaccta aaggaaaagg
     1141 acgaatacgt gtgacatgca aaacatgtgg tataaaattc gaaacgaatg tttaagggag
     1201 aaaagaatga aattagtatt attacgtcat ggcgaaagcg aagcaaattt tgaaaattac
     1261 tggacaggat ggctagatgt cgccttaaca gaaaaaggaa aagaacaagc agcagttgcc
     1321 ggtcaaaaaa tgcttgaagc cggacttcaa ttcgatgccg tttatacctc tgttttgaaa
     1381 cgtgcgattc ttaccggaca agtcgcacta gaagaaatgg gtcagttatg gcttcctata
     1441 ataaaaacat ggcgtctaaa tgaacggcat tatggggatc ttgtgggtaa aaacaaagat
     1501 aagatgaaag aaatatacgg aaaagatcaa gtaaaaacat ggcgcagagg atatacggaa
     1561 gttccgccgt taaccgcaga aaatagattt gaccgcagat atgatcactt ggatccgcat
     1621 ttgatcccat acggagaaag tctggaaatg acagtgaatc ggatcattcc cttatggcaa
     1681 gatcatctag caccaaaact aaaagatcgg caagatttac tagttgtggg tcatggtaat
     1741 agcatccgag cactgacaaa atatttagaa gatgttcctg aagatcaaat ggatacgatc
     1801 gatatcccaa atgcacaacc aatccagtat acattagcag atgatttgac aattctggac
     1861 aaaaaaatac tttaaagaac acctttatct aaaagtgaga gatagaaaaa agaagcaaag
     1921 gaatggaaca aaaggaacat gaaaaattat atatgggact ttgatggtac attgtttgat
     1981 acgtatcccg caatggtaga tggtgcatgg caagcactaa aagattttgg tatcagtatg
     2041 gacaaaaaag aaatctactt caaaatgaaa aagtattcta ctagttattt gatcaatgaa
     2101 tcaaacttga atgccagaga gtttaatgaa ttatttcacc gatatgaaaa agaaagtacg
     2161 gaagtttccc gtccatttcc agaaacgaaa caagtactgg aaatgctaaa agacaacggc
     2221 ggtcgtcatt tcatcctgac ccaccgtttg acagaatcaa catggggcct gttaaaagaa
     2281 catcgattgg cacatctgat tgaggaagta gtagggatcg atcaggactt tcctcgtaaa
     2341 cctgatccag catctttaaa ttatttgatc gatacttttc atttagaaag aacagacacg
     2401 atgatgatcg gcgatcgtcg tttagatatc gaagcaggga aaaatgcagg agtcgctact
     2461 tgtctttacg acatcgatca ttttctgggt gagatcccgg cagattatgt ggtaggaaat
     2521 ctgaatgaaa tccttacctt gcagagcatc attaaaaagt agtatcccct ttcaaaggag
     2581 atatgttata attttcataa aggagtgata aaattatatg gaaatcagaa gacaaaaaga
     2641 agttgtagaa gcatttcatt atgatatgag attgccgaac caagaagtag aaacagattt
     2701 gaaagtaggc ttctcgcctt taaaagaaac gatcgaaaac tatccgaaag aacatagcat
     2761 cgtaggagca cgcttagagt tccgtttagt gtttgataca tatgttttat ctggaagtgt
     2821 gagtcagatc aatcatatcc tcaatcggaa aattgaaggt caaaatgatg tcacacaaga
     2881 agaagtggac gagctagtag caccgttatt cgatatcgta cgccgaatgt cttatgaggt
     2941 gacagagatc gccttagatc agcctggggt aaaattgaat tttcaatcag aaaaacaaga
     3001 atagacagta aaaacatacc tgcgatagat taaagctatc acaggtatgt ttttttatta
     3061 ctaattgtaa gcaaaaagaa tgtcatttcg ataaaaatcg tctaaaatat aaaagtcact
     3121 gaaaaaaatt ttttcaggag gatggttgaa gaatcattct cgggaacctt tacttccttc
     3181 gatggacttg tcattaataa tatgaggagg agaaaaatga caacactcat cacagtttta
     3241 gtggttctag tttttgcggc attattatat gtgttctatc gtatgcaaaa gcgccataca
     3301 aaattttcaa cacgcgtctt tacagcatta ggagttggta tcgtctttgg cggtctgctt
     3361 caattgatct ttggtgtaga cgacaaagtc gttactcaat caatggaatg gatcgggatt
     3421 gtaggtcaag gatatgtatc attcttgcaa atgctagtta tgcctttagt gtttatttcg
     3481 atcattggtg cattcacaaa aatgaaagtt tctgaaaagc tagggaaaat tagtgcgact
     3541 gtattgactt ctttacttgg aacaacagct attgcagcat tgatcggaat tggttcaaca
     3601 atgctgttcg gactccaagg agctaaattc acacaaggag ctgcagaaac agcacgaatc
     3661 tctgaactgg caacacgtca ggaaacagtt gaaaacttat cgattccaca gcagatttta
     3721 tcctttatcc ctaaaaacgt ttttgctgat ttagcaggta gtcgtgcaac aagtacgatt
     3781 ggagtcgtta ttttcgcggc atttgtcgga atcgcttatc taggcgtgaa aagaaaagcg
     3841 ccaaaagaag cagcattctt ttcagattta gtcgacagtc tgtataaaat cattatgcgg
     3901 atcgtgacgc ttgttttgcg tttgacacct tatggagtat ttgctttgat gacaaacgtt
     3961 ttggcaacaa gtgattttgc agctatcgtc aatttaggta aatttgtcgt tgcttcttac
     4021 gtagcattgc ttgctgtttt gattgtccac tcactgattt tgattggtgc aaaagtcaat
     4081 ccaatcaact atttcaaaaa agcctttccg gtattgagct ttgcgtttac ttcacgttca
     4141 agtgctggag ctttgccatt gaatatcgag actcagacaa aagctttagg agtagatgat
     4201 gcaacagcta atttctcagc aagttttggt ttgtctattg gacaaaacgg ctgtgctggc
     4261 gtttatccag ctatgttggc aacgatcgtc gcaccagcag ctggagtgaa tgtctttagt
     4321 ttggaattta ttttgatgct tgtggcaatt gtaacaatca gttcttttgg tgtagctgga
     4381 gtcggtgggg gcgcaacatt tgcttcactg atcgttttag gggcaatgaa cttgccagta
     4441 gcaatcgttg ggttagttat ctctgttgaa ccattaatcg atatggcacg tacagcagta
     4501 aacgtcagcg gtagcatggt agctggtatc gtgacaagtg cacgcatcaa agatttagat
     4561 cgcgatgtca tcaatgatga ttctaaagtg atcgatgtga atgcatagtc aaaaagaggt
     4621 tgtgatagaa gtggtcagct ttaagaaata agaagaagtt tcctaaaaat agtttctcaa
     4681 atttttgtga aatttcggct tatttccgag aagctacttc tgaaacaccg tgaataagag
     4741 gttg
//
LOCUS       DADGHT010000143         4713 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.146, whole genome shotgun sequence.
ACCESSION   DADGHT010000143 DADGHT010000000
VERSION     DADGHT010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4713
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.146"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1549)
                     /locus_tag="JX887_002660"
     CDS             complement(<1..1549)
                     /locus_tag="JX887_002660"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAX1258587.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPN"
     gene            complement(2742..4082)
                     /gene="glnA"
                     /locus_tag="JX887_002661"
     CDS             complement(2742..4082)
                     /gene="glnA"
                     /locus_tag="JX887_002661"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAX1258588.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(4110..4502)
                     /locus_tag="JX887_002662"
     CDS             complement(4110..4502)
                     /locus_tag="JX887_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAX1258589.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         1387 a         1019 c          775 g         1532 t
ORIGIN      
        1 gatttggacg agaaatcaat tctgggtgga attggcatcc cacaaagaat tttttctctg
       61 gcagctctac gatttctact aaacggttat ctggtgagac acctgaaaag actagccctt
      121 gttcttcaaa caattgacga tatttgttat tgaactcata gcggtgacgg tgacgttctt
      181 gcacaacatc ggctccatca tatgcttcag ccgtcttcgt tccttttttg attttacatg
      241 ggtataatcc aaggcgtaaa gttccaccca aattctcgat gttttcctga tcagccatta
      301 aatcaataat attgtttgct gtatctggat tcgtttcagc tgatgacgca tcttctaatc
      361 caacgacgtt acgtgcaaat tcgacacaag ccatctgcat accaagacaa atacctaaaa
      421 acggaacgtc attttcgcga gcataacgaa tcgcttcgat tttcccttct actccgcgat
      481 caccaaatcc accaggaacc aagattccat ctgcgtcttt caaacgttct tctacatttt
      541 ctctcgttaa ttcttgtgct ttgatccaat cgatctcgat gtctgaatta taggcgaaac
      601 cagaatgttt caatgcttca actactgaga tatatgcatc tggtaactcg acatatttac
      661 cgacaagcgc aatccgtact tttttcttca agttcaagac acgttcttct aattctttcc
      721 attctgtcat gtctgcttct ggtgtatcta gttttaaatg gtcgcaaaca atttgatcca
      781 ttccttgtgc ttgtaaaact aatgggatgg agtaaagtgt atctacatct ggcgactcga
      841 taactgcttc tggttcgaca tcacaaaatt gtgccaattt gtttttcacg ctttgagaaa
      901 caggttgctc tgtacgtacc accaaaatat tcggttggat acctaaacca cgtagctctt
      961 ttacactgtg ctgcgttggt ttagttttca tttctccagc agctttcaag taaggaatca
     1021 atgttgtatg gatatacata acattatctg taccgacatc tgctttcatt tgacgaagtg
     1081 cttcaaggaa tggcaaagat tctatatccc ctactgttcc ccctacttct gtaatgatca
     1141 catctgaatc agtcatttta gctgctcgca tgattttttc tttgatctca tttgtaatat
     1201 gaggaataac ttgaacagtt gctcccaagt attcgccctt acgttcttta cgcaaaactt
     1261 cagaatagat ttttcctgtc gtcacgttgg agtatttgtt caaattgatg tcaataaaac
     1321 gttcgtagtg gcccagatcc aaatctgttt cagcaccatc atctgttacg aatacttctc
     1381 cgtgctgata tgggctcatc gtccccggat ccacgttgat gtatggatca aatttttgga
     1441 tagttacttt taagccgcgg tttttcaata agcgtcctaa agaagctgca acaatccctt
     1501 ttccgattga tgaaacgaca ccgccggtca caaaaatata ttttgtcata agttcaaaaa
     1561 ctccttttta atttatgtgc aggaaaagtc tcagacaata aacaaagctc cctattcttc
     1621 aataagaata gggagccgaa atttctgtaa acttctgacc ctctaaaagg gtgcccaagg
     1681 tgtataatac aagctgacta agggaaagtc aagtactcaa atgaatacta tccgcttaca
     1741 attttttctt tttcgatatc ctttgagaaa ttatttctta agtcctttat gagtgcaaaa
     1801 aaaatttaac ccacataata agcttgatat aaacatagct aacgttaaac ctaagcaaat
     1861 cagaaaatcg ttactgaaaa attttaagtg aaataataga taaaaaaata aaacaaacat
     1921 tatgatagat aatatcccac ctaacaaaga actacttttt cctacttgca gcaacagttt
     1981 atatagctta tcgtagaaac aatctttttc tttcaccctt atttacctcc tttacgtaaa
     2041 aaacgtagtc cacagttctc ggatttttgg catatctttt ctattaaata atatcaaaaa
     2101 caaaacaatt ccactaattt tttcaaagat gacctttttt tcaacaaaag tgccttgtag
     2161 ggattcattg aaggtaacga atcacataag taaaaaataa ggagatgcga caaaagtcgt
     2221 gcctccttat ttctaaataa acggtgttct cctgccaact cctcggtcac aagtcacaat
     2281 atccatcaaa catgagaagc tgtttttgaa attatttctt gtgattcgga gttaaatggt
     2341 aggctcacaa cctctggata aacggtattc aaaagccagt ttctcggtat taagccaaat
     2401 ttatgcaaaa atgtagaaag ccattttcac aaaatttttc ttaatactcg aaactaaacg
     2461 tctttttcaa aacctcttgg taaacggtgt tcaaaagctt gcatctgcgg taataagttc
     2521 agccaattca aaaacaagaa aagctgtttt tgcttggcta ttcttattac ttgttgcagg
     2581 gcagcttttt cacaacctct ccactaaacg gtgttcaatc agctgaccct cggtattagc
     2641 tcaaaaaacg gcaaaatatg aggaactatt tttccgttag tttctctaat actcaggtca
     2701 aaacgctgat ttcacagcct ctaattcacg gtattcctgt tttaataaag ttctagatat
     2761 tgttctcttt cccactcgga aacagtttgt ctgaatgccg cccattcgag acgttttgct
     2821 tcaacaaaat ttgagaagat atgttgtcct aatgcgtcaa tcattacatt atccttacgc
     2881 aattctttga tagcattatg gatagttgaa ggtaagtcct ggatatgtgc agcttctctt
     2941 tcttcctcat ccattacata aatgttacgg tcaacagctg ctggcggtgt gatctgatta
     3001 cggataccgt ctagtcctgc ttgcaacaat actgccattg ccaagtatgg gtttgcagat
     3061 ggatcaactg accgcaattc caaacgtgtg gataaaccgc gagattctgg tacacgtact
     3121 aatggcgaac gattacggcc actccatgcg acataaacag gcgcttcata acctggaacg
     3181 agacgtttat aagaattgac tgttggattg caaacggctg tgtaggcacg agcatgtttc
     3241 agcaaaccac ctaagaaatg ataagctgtt tcacttagtt ccaattcacc gtctttatca
     3301 tagaaaacat ttccttcatc attgaacaaa gacatattgc aatgcatacc agaaccattg
     3361 atcccaaata acggtttcgg catgaaagtc gcgtgaagtc catgcttgcg tgcaatcgtt
     3421 ttgacaacga gcttgaaggt ttggatatta tcacaagcat ctaccacatc tgcatattta
     3481 aagtcaattt catgctgtcc tggcgctact tcatgatgtg aagcttccac ttcaaagcct
     3541 agactttcta attccaacac gatgtcacgg cggcaatttt cacctaaatc tgttggtgca
     3601 aaatcaaaat aaccaccttt atcattcaag gtcgttgtga tcccaccgtc ttcgtctaat
     3661 ttaaataaga agaattctgg ttcaggtcct aaattgaaag aggtaaaacc aaggtcgcgc
     3721 atatctttca atgctcgttt caaattcccg cgaggatcgc cggcaaatgg tgtcccatcc
     3781 ggattataga tatcacaaat taaacgagca acttttccat gagcactttc ccacgggaag
     3841 atcatccaag tggagagatc tggatacaaa tacatatcgc tttcttcaat tcgaacaaat
     3901 ccttcaatcg aagaaccgtc aaacatcatt ttattttcta atactttgtc gatctggctc
     3961 actggaactt ctacattttt gatcgtacct aagatgtctg tgaacatcaa tcgtaaaaat
     4021 cgtacgtttt cttcctcaat gattcgtttg atttcttcac ctgttatctg tttctttacc
     4081 atggtatccc tcttcctttt ttaatttatt cagtcaaaga attgtctttg caatccttgc
     4141 gactgataat gacctgtttt gcttaaccca ccttgcgcca aaatctcatc acgaaaaatt
     4201 tgtcgaacgt catgatctgt caacggcttc ttgttttttg cttcttgttt tttcgcctgt
     4261 gccatttcgt atacacgttt gatcccagcc atattcaatc cctctgaaag atagtcttta
     4321 atctcaagca acatatcaat atcattcagc gaatacatac gtcggtttcc ttcgcttcgt
     4381 tccggatgaa ctaaatcttg ttcttcataa tagcgaattt gccgagcaga caaatcagtc
     4441 agcttcataa ctgtaccaat tggaaatacg gacatagatc ggcgcaattc cttttctccc
     4501 atcagacgtc ccctttcgtt ttataagttg gctaaagtgt accaattaaa aaaaatattg
     4561 tcaactgcat atgttaggtt ttctaacatg agatctctat tttttataaa ataacaaaaa
     4621 aataagaaca caaaaaaggt atctagttga ttttcgtacc agataccttt tattttttat
     4681 tatactgtac tatcctttat tagtgttttt att
//
LOCUS       DADGHT010000144         4586 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.147, whole genome shotgun sequence.
ACCESSION   DADGHT010000144 DADGHT010000000
VERSION     DADGHT010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.147"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            186..2855
                     /locus_tag="JX887_002663"
     CDS             186..2855
                     /locus_tag="JX887_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAX1258590.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="JX887_002664"
     CDS             complement(2946..3566)
                     /locus_tag="JX887_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAX1258591.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3679..4218
                     /locus_tag="JX887_002665"
     CDS             3679..4218
                     /locus_tag="JX887_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258592.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4215..4553
                     /locus_tag="JX887_002666"
     CDS             4215..4553
                     /locus_tag="JX887_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HAX1258593.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1418 a          790 c          860 g         1518 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa ataacggtgt
     3601 acatttttaa aaggagatgt ataatcgaga tttagaaagc gttttcctca aaatttaatg
     3661 aattaggaag tgattactat gaaaaaatta tttagcgcac tttttattct gttatttggc
     3721 tttattggta ttgggacttc tggaaatata gttaaagcta gcacgatggt tgaacaaaca
     3781 agtgaaatgg caaaaacttt tagtcaatta acaccagaag aacaaagtta cttcaaatcc
     3841 aaaggattta gtgataaaga tactttttac actcaaaaga tagagcctca agatccgaaa
     3901 acacgttttt ctgcaaatgt attgcggtta accgcatcta ctaaaaaaat tactaatacg
     3961 caggggcgga cagaatatat tataacaagt cccaattcgg cgatgtatcg tatttctaca
     4021 cgcttgagtt taggtagtgc aaaatcatat actcaaacag taaatctagc taattcttat
     4081 ggttatggtg gaggaatgta ttttacattt actgggaaaa gacaatatta cagtgtaaaa
     4141 ttagctatgc aagtttataa tacatttggt gtagggtcag tctcttgcac tgcgggagga
     4201 ttgacaatag gaaaatgata atttcttact atgtcttaaa tagaagtgat gatgaaggac
     4261 tcttcgtttt tcaatcatta catgaggata cgatgctaaa agagttttat aatcggatta
     4321 agaataaaca gatagaaaca aatttatatt ttttaagtga ctctatcttg ccttttatta
     4381 gcaaccctaa aattcttaac ttgttgcaga caaaagattt gaaaagttta ccgattattg
     4441 tcattgatga ggaaattgta aaatatggcg cttatctaag cgtagaagaa ttagaaaaat
     4501 taactaacat tggaatgagt attcaggagg ataatggggt acatggaaca tagaatgaat
     4561 atgcacagtt gagaacggaa tttgac
//
LOCUS       DADGHT010000145         4462 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.149, whole genome shotgun sequence.
ACCESSION   DADGHT010000145 DADGHT010000000
VERSION     DADGHT010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.149"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(458..883)
                     /locus_tag="JX887_002667"
     CDS             complement(458..883)
                     /locus_tag="JX887_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258594.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1257..2228
                     /locus_tag="JX887_002668"
     CDS             1257..2228
                     /locus_tag="JX887_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAX1258595.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2260..3657
                     /locus_tag="JX887_002669"
     CDS             2260..3657
                     /locus_tag="JX887_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAX1258596.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3816..4439
                     /locus_tag="JX887_002670"
     CDS             3816..4439
                     /locus_tag="JX887_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258597.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
BASE COUNT         1561 a          717 c          910 g         1274 t
ORIGIN      
        1 attactacgt gatgtagaat aagcctttct atcgtttggt tattttatat tcaaatattt
       61 gaaataaata aatctttact ctttgatttg taaactgaaa tgatccactg tttgttttac
      121 tgatgaagct tgatcaaagg aagaagctga gtttgaagtt cataaaaatc agccatagtg
      181 agttttgctt ggatttgttt atcttcttct actttttaca taattttgaa caggataaga
      241 ttcaaatgtt ttaaatgaat ctttgactag tttgtgacag ttgtcgcata tgctcaagct
      301 tccttggtca ttaaattctg tatggatatt tttgttgtta ttacatgtac aataatcagg
      361 actatcgatc atccatttcg tctcctttac aatcatcttg cttctttact atagcagaaa
      421 agaaggggag aaacaaaaga agatccaaca gacggcacta tagactgtag atgttgccat
      481 cctcatcctt caaacggtaa ttaccgattt ttgtaaatat gactgttgtt tcttttttat
      541 tttcttttcc tgaaataata tattcgtcat ctttggtagt gatcttgata tctgtcagca
      601 ctgttttttc ttcagatgat tcagaagaat cagttccttg tgtctgatac gtgcgtgtcc
      661 attccatttt tttatctgta aatgtcaact gtcccgcgga taaatccata tctttacgta
      721 cttttagcgt atatacactg ttggtggtat ctgctttttc cgcttttaag acagaagaat
      781 cggttgtttc gtccgaggat tggtcagagc cgccaaacaa atcacagcca gtcaatgtca
      841 aaagtcccgc agacaaaata aatagtacga ttaatttctt caaaatactt cccccatttg
      901 ataggataaa gaaattatac cattggaatg taaaacttca aacggatgga agagaaaaac
      961 gcacaaaaca cccacaaata gagtaaattt tagaataaaa ttttaaaaag gcaaaaaatc
     1021 cgccactttc agaaagcgtt ttaaaaaagt gttgcaatct tttaaaaaaa tgctatatta
     1081 aaaatgaacc ggttcaaata cttgtttaag tataattaat agtgagagga agttgctcta
     1141 ctgaagactt tagttatatg gatattgatg acaagcaaca ctatgcaaag aatgcggtca
     1201 tcataatcga acaacaagaa agagaaatca aatgtaactg gcaggagtga gaatgtatgg
     1261 catcgatccg tgatgtggct aagatggctg gtgtttcagt gggaacagtt tcccgttact
     1321 tgaatggtca gcaactgaag gaaaagaaca tgaaaaaaat agcagaagcg atttcagcgt
     1381 tggactataa agaaaacatc attgctaaag ggttgaagaa taatcgaagc ttctctattg
     1441 gacttttgat aaacgggatt tccagccgtt ttgggtcgga agttgtctca gggatcgaaa
     1501 gagtagctga agaaaatggg tatagcttat tattaagcgg gtttgccgat cagccagaaa
     1561 aaattgaaca aaaaattgaa tacctgatga agcatgtgat cgatgggctg attgtcttct
     1621 tatccgaaga agagtggtct ggatttgaaa tgctcacaaa aatgagtatt ccagttatcg
     1681 cattgaattg tccagaagga ccagcaggta ttgatacaat attagtgaat gatcgagaaa
     1741 gtgtagcaaa agtgatcgct catcatggtg aacaaggaca taaaaaaatc ggatttattg
     1801 ctgccactca aacagactac gtagcaagag aacgtttagc aggagccaaa gaagcggtcc
     1861 aaaatgatcc atcgatccaa ttagaggtct ttacaggaga ctattctaga aaaagcggct
     1921 attacggggc aaaagcatta ttagaaaaag gggcaactgc tatttttgtc agcaattaca
     1981 atatgtcgat tggtgccatc gaatgtttca atcaagaagg tgtcagaatc gggaaggata
     2041 ttgcgttcag tcactatgat tatttagata aaaacgatct gagtatcctt ccgaaaatca
     2101 cgatcacgcc accaacagat aaaatcgggg aacgagcagc agaacagctg ttaaaacgaa
     2161 tcaaaaaaga agaggaagaa aatgaaaaag tgattgtgat ggaaaatatc atacatggaa
     2221 tcaactaaaa cgaactaaaa aagaaaaaga ggtgctttga tgaaaaaata tcaatttcca
     2281 gcaaattttt ggtggggttc tgcagcaagt ggcccacaaa cagaaggaag gatttcaggc
     2341 gatggaaaag gagagaacat ttttgattat tggtacaaaa aagaaccgca aaagttcttt
     2401 gatcaagtag gacctgaaaa aacctcgcaa gtttatacga agtatcaaga ggatgtacag
     2461 ttgatgaaac agactgggca taattcattt cgaacatcta tccaatggag ccgtttgata
     2521 cctgatgaat ctggaacaat caacgaagaa gccgttcgtt tctatcatcg ttattttgat
     2581 gagttgattg aaaacggtat cgaacccttt gtgaatctgt atcatttcga tatgccgatg
     2641 tatctgcaag aaaaaggcgg atggttgaac cgagaaacgg ttgaagccta tgaaaaatat
     2701 gccaaaagtt gttttgaatt gtttggttcg aaagtaaaaa aatggtttac tcataatgaa
     2761 ccaatcgttc cagtcgaagc aggttattta tatcgatggc attatccaga agagtcagat
     2821 atgaaaaaag cgatccaagt tggctatcat gaagcgttgg cttcagcgtt agccatcaaa
     2881 tcttaccatg aaatggagca aggtggtgtt attggtatca tcttgaatct gacaccaagc
     2941 tatccaagag acgaatcaaa ccctgaagat gttaaagcag cgcaaatagc agatgcgttc
     3001 ttcaatcgtt cattccttga tccagctgta aaaggcgagt ttccaagtga attgattgag
     3061 atagtaaaag aacttgatct catgcctgtg atccatgcag aggatttgac ggttatcaaa
     3121 gaaaatacag tagatctttt aggtatcaat tattaccagc cacgccgggt aaaagcaaaa
     3181 gaaacaccaa tcgatactaa aaacggtcca atgcctgagg attatttcga caattatgaa
     3241 atgcctggtc gtaaaatgaa tccttatcgc ggatgggaga tctatgaaca aggaatctat
     3301 gatattttga tcaatgtacg agatcattat ggaaatatcg actgctttat ttctgaaaac
     3361 ggtatgggtg tagaaaacga agcacgattt atcaaagaag atggcatgat ccacgatgat
     3421 tatcggatcg aatttgtcca atctcatctg aaatatgtcc atcaagccat tcaagaaggt
     3481 gccaattgtt taggctatca tatgtggaca tgtatggata actggtcgtg gaccaatgca
     3541 tataagaatc gatatggctt tatttcagta gacttagcac aagatggaaa aagaacaatc
     3601 aaaaaatcgg gtcattggtt caaagacgta tcagataaaa acggatttga ggcttaagaa
     3661 agaatagttg agagcaaatg cgtgaaattc tccattctta ccattttgtg aaaaagaagt
     3721 tcaattattt acgatctttt tcaacttttt tgtctttcta tttcattttt tgtatataat
     3781 agaatagtca aaattaaata ggagtggagg aaagcatgag gaaaaaaaga ccgtttcttc
     3841 tcttttggtt attcggtttt ttcttactgc ttattttatc cgcagcattt tcaggaaaaa
     3901 tgacagcaga tcttgctcag aaagaaacag aaaaaatcgt agcaagcaaa gaatcagtag
     3961 ataatttcaa aaaagaattc tcaacttatt ggtgggcgga gtataaaata actgccaatt
     4021 acgaaaaagg cgaattggac atttatttgc caaaaggaaa agaagaaaat caatttatta
     4081 atatcgatga cgtacttagt gcgatttctc tcagacaata tcaatttaaa gacaagcatt
     4141 tgaccgtttt gcttttgact catgatggcg acaaagtagc ccgtttgaaa aatggaaaag
     4201 tgatcaccgc ttattctgaa aaagtagaca aaaaagtggt cgccgatcgt ttagcggaat
     4261 ggaaaaagac aaatgaacaa gtcaagaaaa caactgtctc ttctcaaaaa aacgagtcga
     4321 caggaacaag tccttcagat tctggcagtg gacaaacgat aacgggaagt gaagaaaatc
     4381 aagcctcaat tattacgaat gagtcatcac aaggacaata tcaatcctat ggacaatgaa
     4441 aaacagaggt tgtgaaatca gc
//
LOCUS       DADGHT010000146         4433 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.150, whole genome shotgun sequence.
ACCESSION   DADGHT010000146 DADGHT010000000
VERSION     DADGHT010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.150"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(543..2048)
                     /locus_tag="JX887_002671"
     CDS             complement(543..2048)
                     /locus_tag="JX887_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1258598.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="JX887_002672"
     CDS             complement(2045..2731)
                     /locus_tag="JX887_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1258599.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="JX887_002673"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="JX887_002673"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAX1258600.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1546 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat att
//
LOCUS       DADGHT010000147         4418 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.151, whole genome shotgun sequence.
ACCESSION   DADGHT010000147 DADGHT010000000
VERSION     DADGHT010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.151"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            59..913
                     /locus_tag="JX887_002674"
     CDS             59..913
                     /locus_tag="JX887_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAX1258601.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="JX887_002675"
     CDS             1010..3259
                     /locus_tag="JX887_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAX1258602.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3262..>4418
                     /locus_tag="JX887_002676"
     CDS             3262..>4418
                     /locus_tag="JX887_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1258603.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRV"
BASE COUNT         1556 a          625 c          807 g         1430 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga tatcggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatc gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga tttgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actagagt
//
LOCUS       DADGHT010000148         4338 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.152, whole genome shotgun sequence.
ACCESSION   DADGHT010000148 DADGHT010000000
VERSION     DADGHT010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.152"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(693..986)
                     /locus_tag="JX887_002677"
     CDS             complement(693..986)
                     /locus_tag="JX887_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAX1258604.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(1389..2567)
                     /locus_tag="JX887_002678"
     CDS             complement(1389..2567)
                     /locus_tag="JX887_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1258605.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(2671..2985)
                     /locus_tag="JX887_002679"
     CDS             complement(2671..2985)
                     /locus_tag="JX887_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1258606.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            3092..3307
                     /locus_tag="JX887_002680"
     CDS             3092..3307
                     /locus_tag="JX887_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258607.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(3607..3849)
                     /locus_tag="JX887_002681"
     CDS             complement(3607..3849)
                     /locus_tag="JX887_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1258608.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(3836..4264)
                     /locus_tag="JX887_002682"
     CDS             complement(3836..4264)
                     /locus_tag="JX887_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAX1258609.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         1376 a          826 c          649 g         1487 t
ORIGIN      
        1 tatttttaaa taaaaaatac tcttttttta cgattattga aaaaaaaaga taaaacttga
       61 ttaattgaag tattgcttaa atttggaagc tatgagggaa gaataaaaga gttaggacgg
      121 gattatctac tatttttctt tgttttaaat atttgttatc tttgaacata aaagagaaat
      181 gtgtcgactg cagtgttgtg tccctcatca cgaataaacg gtgttcaatt agctgatctt
      241 gtattcactt aaaaaatggt aaagtacgag ttgctattcc ccattttcaa ttttctaacg
      301 ctcaggacaa aatactgttt tcacaacctc attggaataa aagcatatat attgtttcaa
      361 gaacgaaatc ttgttatctt tttaaagggc atctgtccaa aatctaattt taggaggtac
      421 gttttggtat ttattcgtac aaataaaaga gaattatctt tattcatgta acgcatccaa
      481 ttgatttttt catgtacgct cctggaacga ttttactgac gattgcttat ttaactgcga
      541 atcgctcatt agcttttatc atagctatcc atattttgaa taacgttctt ggctttgtat
      601 tatagataca gatgacaaaa aaagttcaag tatgcggtgt agaaccaata tcgcatactt
      661 gaactttttt caatgagtat aaattaaaac ttctaatttt caattcccat catctgatat
      721 gcccgaccgt ctgaacttct tttgaaaaag ccaaatgtga ttagataacg tctttgttcg
      781 acataatcgc cactagaaaa tacgttcagc agtatcgaat taacctctgt ttctgtataa
      841 gtcactccat ggtcaaagcg tttcaagact tctttcaata ggatgtattt cttttttgtt
      901 gaacttggta cttgttttac ttttccatca ttcatgaatg tgtctaaaac tttcatcttt
      961 tcttgctccg tataagtata aaccatcttc tttctccttt tgattctaag aatactccat
     1021 ttatgttaga atattctgga ttttttatta aagcggttac tcttaagaaa gatattatca
     1081 tagtgctctt ttttttacta ctacttatag gtagatttat tctaatccat tattctcccc
     1141 taccaataat taaagaaaaa actggatcag ggtgttcaaa ttacatgcta agaaaaaaga
     1201 acccttgaat accaagggtt ctttctcagt ctgataacaa tgattaacga cggatttctt
     1261 tgatacttgt gaaaagtcgt taaagtattg atataaaagg atttttatta cctctgacta
     1321 catattgact aatttgttaa aaaatcgttt ttcaagaatc ctgtaatacc agtgctttca
     1381 ccgttttttt aactctctaa agaactaaaa gcaatcagag gttttacctt ttcatttgac
     1441 gttaagtggc gataaatttt cgaagttgtt tggtcagtat ggcctaagcg atctttcaag
     1501 acttcccagc tacagtgttc cgctactaag cttgccattg tatgacgagc taaatgagta
     1561 tgaaatggct tattaattcc tgagcgattc acgcaccgtt tgacgtgatc atttacatac
     1621 tctcgacgat aaggaacacc acgtttacta gaatcaagat acacaaacaa atatgtttct
     1681 tctataataa acctgtaatg ttgcctcatc tcacccaaag ccttaatcaa ctgttgtagc
     1741 ttttccataa ctagaggagt tactagaact cgtctagcag aactaactgt cttagtagtt
     1801 tcaattcgaa aatccttact cttaccttta actgccgttt gcttatagaa cagaatttca
     1861 tttcttttga aatctatatc tccaggctgt agagcaagcg cctcgctgac tcggcagcca
     1921 gtgtaaaata gaacatggaa aagtacagac atcggtaatt cctcatgaac aatgccataa
     1981 ttcaaaaaag ttctcaattc atcgacagta agaaacttgt cctcaatatt atttatggct
     2041 tcttttaaat cagttaccgt taactgatat tttggcattc tcacagactt cattggattt
     2101 tcacttatca aattctttct ttgacaatat ttaaaaatca tatttagaac ttgaataagt
     2161 gattgtaaac tatttttggc atagccaaca tttgttccat taacgccaca ttcctttaag
     2221 gtaaaaagca attcttgaag gcactctggt gtcaaatcag acaacttttt atcaccaatc
     2281 catcgaacaa taatttttaa ttgttcctct cgcttatcat aggttatttc cttttgttca
     2341 tttaacgaac ggtaatattg gaaccattgc tcacctacaa cactaaactt gtcattgctt
     2401 gcaacaattt ttttcttaag cctttgttgt ttctccattt ccagataagc gagttgcgcc
     2461 tcacgttttg aattaaagcc acgtcttgtt gttcgatatg cttgaaagta ccatgtgatc
     2521 ctaccagtag aactgatttg cttcttgaat cgatctgttt tttccattta ttgattcctc
     2581 ctattttgaa ggaacccaac aagcagaaac cctttggaaa tctttctatc tatgtcatca
     2641 ttgtaccgca tcttagaaag aaaatgtaac ttataaagat cgaagtagtc gcaatttttc
     2701 tcgatagtca ttcgaatcac tctttctcat ccattctaaa acatcatcac gaaaatagtg
     2761 tcctcgaatc ccgtaccaac agggaggaaa ctcaccaagt tttactaaac ggttcagtgt
     2821 actatcactt atctgaaata gtcgctttaa atcagtattt gttaatacca gaggtaaatg
     2881 actgactgca agcaattttt ccgtgtaatc ttccagtttt ttttgtaaaa ttgaatagaa
     2941 ctctatttcc agagaattaa catttgtttt aacttccaac tccatcaccc ttctctctca
     3001 aaatcaaaac gaccaccacg gtacccctta aaattgtaaa aaaacactcc agtactccat
     3061 caaaacggac tagaaaagag gaatttttaa tatgaaacaa ggaattgcag acataaaaat
     3121 aattaaagaa attcttgaaa aatctacggc taatgcaata gcattcggaa caggaatcaa
     3181 cttgagtaca gtaaaaaaac ttaaaagtgg agagagagct gaagaaaaat taaatcttgc
     3241 cgatgctatt aaaatcacag aatttggcat gaaaaatatg ccaaccaaaa tcgaaatatg
     3301 gaaatagtag tttttctgat ctatcagctg ttttgccaaa gcacatagga atctcacctc
     3361 cccccagtaa tggcgggccg atttggttac ggaagtatca ttatcgtagt cgcgattctc
     3421 atattaaaat ttgtcgctta aaagctaacc ttgtcatggc gtaactagag aatcaaaatc
     3481 tacatgtact gatagatttg ctattcattt gtcaaagagc gctaggctat tttcagccta
     3541 tggaaatcct ttattttgac ccgataaaaa acttccatag aatgaaaagg aaagggaaaa
     3601 aatactttaa cgagttgtat caaattcaag tatcttctca atcaattttg tttccagttg
     3661 tctacgcata tattcatcta catacataac cattcctttt tcttcttcat aaactggttt
     3721 catggctaac cgtgaaatat aattttgata ttttgacaga acgatggaca tggcaattga
     3781 atcaccagaa gctgcggctt tgattgtcgt tagtggtatg aatggtatat atcgtttatt
     3841 ttgcttcata tttgacaccc aaatactttc ctagctcttc caaagccatt tgtcgttggt
     3901 accaaacact gccgagactt ttcccaataa tatcgccaat ttcacgatca ttaagaccga
     3961 tgaagaagga cataaaaatg atttcttgtc tttgactagg taatgctgca atcgcatttg
     4021 ccaactcctc attggaaata aagattttca taccaaggac aataaaagta ccactactat
     4081 tcaaatttgg ttccaaataa tagaactctg tacctaaccc tttttgttcc aatatttcca
     4141 ttgatatttg ccgttggcga aatctagcgt acttcttttg aatatttaac gcctcattgc
     4201 agactacttt cttacaaaaa ctgtcaaacg tatgttgaat gtgggtttcc tctgagtcgc
     4261 ccataatatt ctccccctca aaaaattcat tcaactcgtt ttacttctat ccctttccat
     4321 tattactaca atctagga
//
LOCUS       DADGHT010000149         4335 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.153, whole genome shotgun sequence.
ACCESSION   DADGHT010000149 DADGHT010000000
VERSION     DADGHT010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.153"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            127..579
                     /locus_tag="JX887_002683"
     CDS             127..579
                     /locus_tag="JX887_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258610.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="JX887_002684"
     CDS             593..1282
                     /locus_tag="JX887_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258611.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="JX887_002685"
     CDS             1407..3758
                     /locus_tag="JX887_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAX1258612.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="JX887_002686"
     CDS             3838..4233
                     /locus_tag="JX887_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258613.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
BASE COUNT         1526 a          548 c          867 g         1394 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatt
//
LOCUS       DADGHT010000150         4241 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.154, whole genome shotgun sequence.
ACCESSION   DADGHT010000150 DADGHT010000000
VERSION     DADGHT010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.154"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            285..881
                     /locus_tag="JX887_002687"
     CDS             285..881
                     /locus_tag="JX887_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAX1258614.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(939..1421)
                     /locus_tag="JX887_002688"
     CDS             complement(939..1421)
                     /locus_tag="JX887_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258615.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1527..1724)
                     /locus_tag="JX887_002689"
     CDS             complement(1527..1724)
                     /locus_tag="JX887_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258616.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            2019..2777
                     /locus_tag="JX887_002690"
     CDS             2019..2777
                     /locus_tag="JX887_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAX1258617.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            2837..3265
                     /locus_tag="JX887_002691"
     CDS             2837..3265
                     /locus_tag="JX887_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258618.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            3311..3383
                     /locus_tag="JX887_002692"
     tRNA            3311..3383
                     /locus_tag="JX887_002692"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3344..3346,aa:Gln,seq:ctg)
     gene            complement(3533..3904)
                     /locus_tag="JX887_002693"
     CDS             complement(3533..3904)
                     /locus_tag="JX887_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAX1258619.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
BASE COUNT         1434 a          804 c          681 g         1322 t
ORIGIN      
        1 aagcaagtaa tttttaatgg caatatcata aaaaaaaaga agatagagat ttaataatta
       61 tatatcagct gtttttttca aataagcaaa aattcctaaa acacaacaat gaaagcgata
      121 actaagaaaa tccttacata acgatttttc ttattaaaat tgttttttga acttcgctta
      181 ttttttgtga gcatatctgt ttacttactt tttgtaaggt gctatacttc atttcgtaat
      241 caattaaaaa aatgcaaaac gcaaatcaaa ggagaaattt tattatgaca acttttactg
      301 acactttgaa aaaccgccgt tcaatctatc atctaggacg taatgtttca ctttctaatg
      361 aagaattaac aactttgatc aaagaagcaa ttaaagaaag cccaactgct ttcaatgctc
      421 aatcaacacg cgcagttatc cttttcggag atgcacatga aaaactttgg gaaatcactg
      481 aagaagcact tcgcccattg actccagcag aagctttccc aaatacacaa aacaaattag
      541 ctggtttcaa aaatggttat ggtacagtat tattcttcaa agatactgac gtggtaaaag
      601 gtctacaaga acaatttgaa ttatatgcag acaacttccc agattggtca gaacaatcaa
      661 acggaatcgc aacagctaat acttgggtag cattagttga taaaggattg ggcgcaaact
      721 tgcaacatta caacccagtt attgacgaag cagttgcaaa agaatggaat atcccttcaa
      781 actggaaact acgttcgcaa ttagtattcg gttcaccaga aacaccggct gaggaaaaag
      841 aatacatgaa cgatgccgat cgcttccgcg tatttggata attttatttg aaataaaaaa
      901 cagaggttgt gacaaacatc ttgtcgcaac ctctgttttt attctggatc aatcataata
      961 tcaatctctg cctcatcgtt taagcgttgg gacaaaaatg gaactaattc ttctaatgat
     1021 gcagaaaatt tcagcatcgg tcctcgccat ccgtttcgga aaaaattcat ttttacgatt
     1081 ttagaacctt ttggctgata taatacaatt ttattgatct cagaaaaagg aacacctttt
     1141 ttgtcaaagc tattcaaaac aagtccttct tctgtgattc ctctactgtc caacaaaaaa
     1201 ctaataaaaa tcattgctga caagatccct tttgccaatt catctgctgt aggatgactg
     1261 atgagtgtat accaaatgac tagtgacact aagaagggta tcaccaagta gacccatcga
     1321 tttcgcacag tccgataaat aatttctttt cgaaccagcc aaagaaataa aaacatcaca
     1381 acaacgaata aaaacaatag aaccgtaaag aatgttacca tgacaactcg cctcgctttt
     1441 tcttctccag aaaataggaa aagaatactg atttaccttc tcaaagaaat tggacttgca
     1501 gcacgccgca cgtccaattg ttttctttat tcaaatgtat catattttgc aacaaccatg
     1561 cttgcttttt catctaataa ttcttggtcc tctgcagcac attgggcaac tttgaccacg
     1621 gcgcagtttg tcatttttga tacaacttca ccaatgaccg tttttgtaaa accaattggt
     1681 ttgcatgcat attgttctcc taaattaatc atttcttccg tcatcaaaat cctcctaaac
     1741 tgctggaact tttctccaca ttaccactgc tatttctttg gagatttaac tcattgattt
     1801 ttatttacag ttaaaaatca accttacagg cattatagcg tactgttttc gttttcacaa
     1861 ttaaaacagc tgttgtattt agaagaattt ttttcaaaaa attaaaacat attccttaaa
     1921 aactaattat ttcctacata ttaaaatata atacttccat ttccaataaa aatacattta
     1981 taataggaaa gataaacagc tgaaaaggga gatttcaaat gaagaaaaaa acgttcaaaa
     2041 aactattgtt tctagggggc acagctgctc ttttattaag cggtacaagt tattacctac
     2101 atatccattc tccagaacat acaatgaaca ctgcacaaaa aagttcaaca caaaaaacga
     2161 aaaagacaaa agagaaagca gaagttttac tagatgttcc attagagagc cagtttgatt
     2221 ctccttcttt agaaaatggc tgtgaagtca cttcgctttc tatgctttta tctttttatg
     2281 gttatgaaac aactaaaaac cagttagctg agcaattgga ttacgtccct gttttcaatg
     2341 cagatgggac tcatggcgat cctaatgaag gatttgttgg tgatatcagt ggcggagact
     2401 gggctatggt cgtctatgtt cccccagttg cctcccttgc tcagcaaatc gtccaaacgg
     2461 attatcacac ttttccaaaa accgatgctc aactcgatga tatcaaaaaa gcactatcta
     2521 aaggaaatcc tgtctggact tctgtgacta tcaattttga agtcccagat gaaactgatt
     2581 ttatgacttg gaccacaaat aatggagaag taagagtcac tcctcttgtt catgcttgtg
     2641 tagtcactgg atatgacaaa gaaaatattt atgtcaacga tccctatggt gtaaaaaatc
     2701 gagcagtacc gatcaacgat ttttcggcga ttttcactgc aatgggtgga cagatgctaa
     2761 ctttggagaa aagctagtaa ttcaaacaaa aatcccttat actcaagata ccaaaccttt
     2821 gaagggagcg tagataatgg aaaaattcac acataaaaaa atggatccaa atgaaattcc
     2881 gattattttt gtccgtgact gcaagggaaa tgttcaaggt aaagtctcta ttaatgagtg
     2941 gaacgagcgt cgcagacctg ctaccctcaa tgaactggaa atcaaattgt atcgtcaatc
     3001 tcttgtttat tacgcagatc aagagtacga gaaagccacc gatttattga aatttctaat
     3061 tgctcgaaca gagtatactc gctttgaata tattgaacgt ttagcaaaca tctatcatat
     3121 tatgaatgaa cctgtcaaag aatatcagtt attggacacc gtcttgtcag tagcagaact
     3181 gattgccctt cctgctggat tagaaaagaa actagtacgc cgccttttac gagtaaagca
     3241 acaactatcc gatcaagaaa aataacttgc gtttttttag gaaagtgcta tgattatttt
     3301 gttgaataaa tgggatgtag ccaaactggt aaggcacttg actctgaatc aagcaattgt
     3361 aggttcgaac cctgccatcc caatttgatg tgcttgctga aaaaatgaac cccctgtaaa
     3421 agaacaatct ttttgcaggg ggattattgt attattttta ctacttgtat ttagtttaca
     3481 taattaaatt atgaataata aaatcgggcg tattcttaat acaaaaactg atttacccaa
     3541 taattgctaa tgctttctcc ggaacttttt ctctaggaac ttcctcatac gtttctatgt
     3601 gtgctccttt attgctaatt ttcaaataat gattttcttt taacacagaa agaccattaa
     3661 attcaaccgt tcgttctttc ccattggcat cagcagcttt ctgcacatac cttgctgtac
     3721 catattcatt tacttcctct ggtttttgtg tctttacata gacctctcct ttttcaacta
     3781 atggatttag ctgatcaagt ataccaggga tttctccata acttccttca gtataatatt
     3841 tcagtccaaa tagcaaaata ccactaatcg ccgccagtcc aatcaaatat ttaatcactt
     3901 tcatctttct acctccttgt tatatattca gtatatgggt cagttaaaga aattccatcc
     3961 gtcccaagtt ggagattttt ctcctacttt agaagcgaga atcgagtgtt tttttagtaa
     4021 aaatgatcgt tatttgatat tattgacgtg tggataaatc agtttttctc gttttgtcca
     4081 tgtaaaaaat catgttgata gcaaaggatg tgttcaaaat gaatcaagaa gaattatttc
     4141 aaaaagtcaa ggaaatgatt aagaacggca atttcgatgg cgcaaaacga tttatcgaag
     4201 aacataaaga acaattagga ccttataaag agaaagccca a
//
LOCUS       DADGHT010000151         4222 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.155, whole genome shotgun sequence.
ACCESSION   DADGHT010000151 DADGHT010000000
VERSION     DADGHT010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.155"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(383..1669)
                     /locus_tag="JX887_002694"
     CDS             complement(383..1669)
                     /locus_tag="JX887_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAX1258620.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(1662..2930)
                     /locus_tag="JX887_002695"
     CDS             complement(1662..2930)
                     /locus_tag="JX887_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAX1258621.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            3182..3643
                     /gene="mscL"
                     /locus_tag="JX887_002696"
     CDS             3182..3643
                     /gene="mscL"
                     /locus_tag="JX887_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAX1258622.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(3702..4148)
                     /locus_tag="JX887_002697"
     CDS             complement(3702..4148)
                     /locus_tag="JX887_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1258623.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         1195 a          862 c          740 g         1425 t
ORIGIN      
        1 ccaaccaagt taaaaacatt aagaagctgt ttttacttgg ctgttcttat tacttgatgc
       61 agggcagctt tttcacaacc tcttggtaca cggtgttcca gaagtagctt cttcggcaat
      121 aagccgaaat atcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
      181 agctgaccac ttctgtcaca acctctttga ttacttcgtt tgattttatt ttaatataag
      241 ttgattaaaa gagagcatga tttgttttat tttctcacta atttttccaa cacaactaag
      301 aataccataa aagctgattt tggaggaggt tcctactaca agtctaaaac gaaatttaag
      361 acttttcctc ataaatactg gtttattttg gtctcatgta aaactcgctg aaggcctctt
      421 cacttataaa tgcttcccca gctgccagta cgtctttcat ttggatcgaa tcgatgattt
      481 caggaagatc aaataaagtt cgatcgccaa ataaactttg cgtaaattga ttggcaatat
      541 attcgatcga atttaatgat tggaaatatt gtccaagcat tttcttcttc agcaaatcga
      601 gatttgtttc tgacacttcc ggatcatcag cgaatccaag aatgatttct ttgacttttt
      661 ctgctgcttt ctctggttcg tccgtatctc cgctgaagtc cgcaaagtga aattcacgat
      721 ccaagctgaa ttcaaaacca aagctgtcat cgataattcc ttgattgtac atcgctagat
      781 agtttcgaga agtattgcct aaaatcattt ggaacaacag attgattgct gttttatagc
      841 gtaacagttc tgttccttct tgcggcaatg tgtctaatcc tttaatacca agtacaaatt
      901 tatctcgtgt aatggctgct tccaatgcac tttgtttgat gatttctttt gtgttttcag
      961 ggaaataacg tacaatttct tgctttggag ggaaattttt tgcttcttgg ttttcccgaa
     1021 taagtttcat caatttctca ggctccatct taccaactac aaataaaacc atattgcttg
     1081 gctgataaaa cgtccgatag cacgtataca agtcttgagc tgtgattttg tcgatacttt
     1141 caaccgtgcc cgcaatatcg atatgcaatg ggtgtgtagg atacaagtta tttagtatgc
     1201 caaaaaacat ccgccagtta gggtcgtctt catacatttg gatttcctga ccgatgattc
     1261 ctttttcctt gtttacagtt tcttctgtga agtaaggtgc ttgtacaaaa tcgatcagag
     1321 tcgtcagatt cttttctacc tgatccgtcg tagaaaacag atagctggtt ttcgtaaaac
     1381 ttgtgaaagc attggcggaa gctccttgtt tcccaaataa ttgaaagaca tcaccatctt
     1441 ctttttcaaa caacttatgt tctaaaaaat gggcaattcc atctggaact ttcacctttt
     1501 ctttttcacc atagggaata aattcgttat cgatcgaacc ataattcgta ctgaacaaac
     1561 catatgtctt gtgatagtca tttttaggca acaaatacac ggtcaaaccg tttggcagta
     1621 cttcatgata aagtgtttca ttgatttgct catattctgt tttattcatt tgcatttcct
     1681 cctgctaaaa agaagattgc ctgcaattcg atttgctcag ctacttgttg tatctctttg
     1741 atcgttacgc tctccatacg tttcaaccat tcttcatcag ataattttgt ttccggcagc
     1801 cagctgtcca aaaaagaagc ttcgattgcc gcttgcggag agtctagaga aagcagatat
     1861 tggtttctca gcattgcttt tgtctgagac agttccaact ctgttatttc accatttcgc
     1921 aaactttcta attgctcgtg aatcagatga agtacttgat ttcggttctt ttcatcgata
     1981 ccggtttgga cactcatgaa tcctcggaac gtatccacgc tactagaggc ataataagct
     2041 agactttctt tctctctgac attcatgaaa agtttagagt gaggaaaacc gccaaataaa
     2101 ccgttaaaga ccattagcgc aaaacgttct ggttcatcgt aatacacatt tgtctgataa
     2161 gctaggttca gctttgcttg aacgattggc tcacgtactt gtcgttcctt cacgatattc
     2221 acttgaggtt gggtataaaa cagatctgga taaactgttt cccgcgactc aaatggtaat
     2281 tgcccaactg cttcagctgc tttgtccgga tcaacatcgc cgacaacaaa aatgtcgatt
     2341 tgatcatttg ccatcatttc ttgatagtag gacgctagcg aactagcagt gatcttgtcc
     2401 aaatcttcga ctacgcccaa ccctgggatc ttttgttccg ggctgttttc aaaataaagt
     2461 tcttgcaagg cataggaagc aaaagtttgt ttatcttcct tcaaactttc caaatataga
     2521 cgcagattgt tcttttccaa gtcaaacgtc aactgatcaa actgatgatt tttaatattt
     2581 ggataaaata aaacctcttt taaaaaatct accgcttgag aaaaaaggtt tggatcattg
     2641 acatattcac cattcacaaa actgatccct gcgtttagcc aatgtaaatt tccttttttt
     2701 ctaactgata atccaaagct tgcgccataa agctctgcaa gttgcgcact taactttgtc
     2761 tgatccggat aattcaaact atttgtttcc aacatgctgc tgagaagtga acgtttcgtg
     2821 atgacttctt gttgcagacg cgcagtaaaa cggataaaaa tccggatcgt tttgtattgt
     2881 tttgttggta agacatgaag attcacgcct tctgccaatt gatacaccat atttatatgc
     2941 tccttttcac agttgattgc ccgcttactc ttttaatggg tcaacctgcc ttttttactt
     3001 attcctctgc ttgaaattta taagttcagg caattcgccg ttttttctaa atgatgttac
     3061 actttatagt atagcataga tgttttttat caaaagaaac agacggctaa aagcgtatat
     3121 tgttttttta ttttttattt ttcgatatac taaagacaaa taaaagaagg gagggtcatt
     3181 catgatcaaa gaattcaaag agttcatcat gcgtggagat gtcttggatc ttgctgtcgg
     3241 cgttgttatt ggtagtgcgt ttacaagcat cgtaaaccaa gtggtgcaag gcttgatcac
     3301 accactaata ggttggtttg tcgcaatgat cacaggtact tctgatttag aaggagcact
     3361 ttcaattctt gactggtcgc cgacaaaagg cgtcacattt gcgtttggta acgttattag
     3421 tgctatcatt acatttctga tcactggttt tgtcttattc ttagttgtca aagcggcaaa
     3481 ccgtgcgaag aatttacgct ccaaagaaga gcaagtggaa gtggaagaaa ctcctactgc
     3541 agaagattat cttagtgaca tacgcgatct tcttgccaaa caagtggcag aagacaatac
     3601 acatccagta gagcaaacaa atctttccga tacttctaaa taataaagaa tctaaaaaaa
     3661 agaaagccga ttttcagtgt cggctttctt tttttagatt cttaacttgc tacttgttcc
     3721 tttttcatgt cgatatgtgg aatatcatct tccaaataca catctgagat tgccttgaat
     3781 ccaaacgact cataaaaagc ttgtaggtat tcttgtgcgc cgatcacgat tggtttttct
     3841 ggaaaatttt tctggatcat gttaatcgtt tcttgaacaa tctttcttcc taaaccatct
     3901 ttacggttgt cctgatgaac aaggacacgt ccaaaatgga tactctccgc ttcttcatat
     3961 actcgcgtgt aggcaaggat cttcccatca gtatcttgaa aaaacgtatg ccaagcttgt
     4021 ccatcaatgt catcaacttc ttgataagga cactgttgtt ccacaacaaa aactgcgatt
     4081 cgttctttga cgatcgcgta aaactctgct gttgacaatt cttcaaattt ctttacctga
     4141 tattccacta agcaaacgcc ccctgctttt ttattcttag cataccgatt cgcacacaaa
     4201 aaagcaaacg aaccttacga at
//
LOCUS       DADGHT010000152         4066 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.157, whole genome shotgun sequence.
ACCESSION   DADGHT010000152 DADGHT010000000
VERSION     DADGHT010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.157"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            85..1434
                     /locus_tag="JX887_002698"
     CDS             85..1434
                     /locus_tag="JX887_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAX1258624.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1562..2152)
                     /locus_tag="JX887_002699"
     CDS             complement(1562..2152)
                     /locus_tag="JX887_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAX1258625.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2299..3651
                     /gene="brnQ"
                     /locus_tag="JX887_002700"
     CDS             2299..3651
                     /gene="brnQ"
                     /locus_tag="JX887_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAX1258626.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1172 a          744 c          789 g         1361 t
ORIGIN      
        1 aaattttgga atcttagttg tgtttttcag aaaactctct taatatggaa gtaattaaac
       61 ttttttagtt aggatgattt aaaaatgaat gaagagcaag aactgcagcg tggactgaaa
      121 aatagacatg tccaactgat ttctattggc ggagcgattg gaacggggtt gtttttaggt
      181 tccggaaagt ctatccagct agctggccct tcgatattgc tcgcctatct tattactgga
      241 tgcatctgtt ttttcattat gcgtgcgtta ggcgaacttc tgttatcaaa caccaataac
      301 cattcttttc tggattttgt tgcagaatat cttggcaaaa aagcggcttt catcactggc
      361 tggacgtatt ggttctgctg ggtatcgatt gcaatggccg atttaacagc catcggaatg
      421 tatgtacgct actgggcgcc tggtgttcct cagtggcttc ctgaactgat tgcattaggt
      481 cttcttcttt gcttgaatat ggtggctgtc tcattgtttg gtgagttaga gttttggttt
      541 gcattgatca aagttgtagc gatcattgcc tttatcctcg taggagctta tatgatcctc
      601 acccactata cgacagatat tggcacagcc agtatcacga atctatggtc tcatggcgga
      661 ttctttccaa ctggtgcaaa aggatttatc ttagctttcc aaatggtaac ctttgctttt
      721 gctgggatag aattagttgg attagtcgct ggagaaacag aaaatcctga aaaagtgttg
      781 ccggaagcta tcaataatat tcctatcagg atcatcttat tttacttagg atctcttttt
      841 gtcattatgg caatctatcc atggaacagc ttgaatccag ataacagtcc atttgtagaa
      901 gtattttcgg aaattgggat cacgattgct gcttccttga tcaatttagt cgtattaagt
      961 gcagcagctt ctgcctgcaa cagtgcaata tatagtacag gacgtatgct tcgttcttta
     1021 gcgcaagaag gcagtgcccc taaaaaattc aaaaagttaa caacacatca tgtgccaggg
     1081 aatgctttga cattttctac tatcgtcatt ttcatttctg ttatcttgaa ttacgtgatg
     1141 cctagtgaag tattcacact agtaagcagt attgccacta cttgtttctt gtttatctgg
     1201 agtatgcttg tctacacgca catgaaatat cgtaaaagta tcctcggcaa aaaagctcat
     1261 tcatttaaaa tgccgttgta cccatttagt aattatctgg tatttcttta catggccttt
     1321 gtgtgtgtcg tcttgttcct aggaaaagat acgagaatcg ctttattact aacacctgtg
     1381 tggttcttgc ttctattact aatctatcat atgaaatatg aacgtaagaa gtaagaaagt
     1441 agttgtgaca gaagtggtca gcttcgagaa ataagaagga atttacgaaa attgcttctt
     1501 aaatttttgt gaaatttcgg cttatttctt ggagataaaa gcttctgtcc cagcctcttt
     1561 tctatttccc cggaaacaac cgctgataat aggcatctgc ttttttatag gaaaaaatcc
     1621 aaataccaga tacaaaaaaa cgtccgaata acccgatcaa cggtacaaaa aagacaccgg
     1681 caatcaagca taagttaatc atcatggaga taagacttcg acggtccttt gacaaaactc
     1741 tcacgacatg ggaatctggt ttatttgctt tcatgatttg cctcatcaag ataccaaaag
     1801 aaaaactcca catcgtgtat actaagacat aagccatctc aggccaaaaa gcttcagggt
     1861 tacgcccgac ccaactagta acagaaggac ataaagtcag ccaaaagagc aaaaagatat
     1921 tcgaccagac cactcggtaa ttaattcgtt ctgccatctg aaatatacga tgatggttca
     1981 cccagatcac cgcaacaaat ataaagctga tggtataagc taataatgta tttcggatga
     2041 cccataaaga atgaaagcta gatgtattag ggatcttgat ctctaataca agaactctca
     2101 aaacaatggc taccactcca tcagtaaatg cttctaatct cgactttgtc acgatgattc
     2161 ctcctcagat gattcagcgc ttttatttta tcacttacgt tattaaataa ccatcgtttt
     2221 atatagggaa ttttctgaaa attgttgcat atttttcgaa attttgttac ttttaaaaaa
     2281 accgtaaagg agttatgtat gacaaaaaaa ttatcattta aagactatct ttttataggc
     2341 tccatgcttt tcggtctatt ttttggtgct ggaaatctta tctttcccgt tcatttgggt
     2401 caagaagcag gcgctgctac cttttgggcg aatctaggtt tcttggttac cggtatcggt
     2461 cttcccttct taggggtgat tgccattggt gtatcgaaaa gctcaggtgt atatgaatta
     2521 gcaaaacgga taaatcaaac atatgcgatg gtttttacca tcttgcttta cttagttatc
     2581 ggaccgtttt ttgctttacc tcgccttgca accacatctt tcgagattgg tttagcacca
     2641 tttatcgatc ctagcagaca gacgctatat ctagcaattt tcagtattgt attttttgtg
     2701 ctggcttggt ggttttcaag aaaaccgaca aagatattag attatgttgg aaagttcctg
     2761 aatcctgcat ttttggtttt attaggtgct ttgcttctcc ttgctttttt gaatccacta
     2821 ggttctgtaa atcaagcgcc tattcagcca aattatcaag agcatgcttt tttcacaggg
     2881 tttactcaag gatataacac attagatgcg cttgctgctt tagcatttgg gatcatcatt
     2941 gtcacaacaa tccaaaacat gggtgtaaca aaacctgctg aaatcgctaa agacacgatc
     3001 aaatctggtg cgatcagcat tatattgatg ggaatcattt atactttgct cgcttattta
     3061 ggtgctatga gcttaggtag ctttgctcta agtgaaaatg gcgggatcac gctggctcag
     3121 attgctgatc attatttagg tacttatggc agtatcttat tagcatttat cgttatatta
     3181 gcttgcttga agaccggtat tggtttgatt acagcttttg cagaaacatt cacagatttg
     3241 tttccgcaaa gaaattacgc attctttgtt gcacttgcta gtatccttcc ttgtttagcg
     3301 gcaaacgtag gcttgacgaa tatcattcaa ttttcgttgc ctgttttgat gttcatctat
     3361 ccattagcaa tgacactgat tttactagtg ttagttggtc ctttgtttaa gcagcgtacg
     3421 gctgtttatc gaatgactac ttattttaca ttgattgctt cgatttttga tgggttgaac
     3481 gcttgcccag aaactatcaa acaaacacct attgttcaaa atcttttata tgttgcggaa
     3541 agctacttgc cgtttttcaa attggggatg gggtggatcg taccagcagt tatcggtttt
     3601 gttatcggac tgatttggag tttcgctaag aaagaagaag tagcagattg ataaaagagg
     3661 ttgtgaaaga gacgttcagc cttgagcaat aaaaagtaat tttgaaaaat ggcttctcac
     3721 atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg tttattgaga
     3781 ggtcgtgaaa aagccgctta gtttcaagta ttaagaaata ttttgtgaaa atggcttctc
     3841 acatttttgc ataaatttga cttaataccg agaaactggc ttttgaacac cgtttattga
     3901 gcgtctataa actgacctga gtattagaga aacaaaacgg caaagtagct ccatatactt
     3961 tgccgttttg ttttgaacta ataccgaaga gaagctgatc aaacaacatt tcttttataa
     4021 tatagatttt agacatatat atgatataaa aatagttttc gcaaaa
//
LOCUS       DADGHT010000153         4063 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.158, whole genome shotgun sequence.
ACCESSION   DADGHT010000153 DADGHT010000000
VERSION     DADGHT010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.158"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            77..769
                     /locus_tag="JX887_002701"
     CDS             77..769
                     /locus_tag="JX887_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAX1258627.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1096..1593
                     /gene="dfrG"
                     /locus_tag="JX887_002702"
     CDS             1096..1593
                     /gene="dfrG"
                     /locus_tag="JX887_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAX1258628.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1665..3617)
                     /locus_tag="JX887_002703"
     CDS             complement(1665..3617)
                     /locus_tag="JX887_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAX1258629.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3624..3920)
                     /locus_tag="JX887_002704"
     CDS             complement(3624..3920)
                     /locus_tag="JX887_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258630.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT         1366 a          689 c          680 g         1328 t
ORIGIN      
        1 tttaaaaacg cttgacattg tgtttgagat cacttacttt tagcatgtaa aagtattgga
       61 ttaaggagct atgcaaatga aaaagaaatt tattactggt gggattgtcg ttgcatttct
      121 atgtctaatt ggctacacag gcacgcggta cgcaaatgaa attattttgt ggggtggaga
      181 gacagatatt gatacaatca atgagaatct gacacagctt gatcatacat tgacagataa
      241 agagcaagcg attacagatc ttaccgctcg actagcacaa aaagaacaga cattgcaaga
      301 ttcaaaggca gatgtccaag aataccaaac aaaagtaaat gaattagaaa accaaaaaaa
      361 tcaatcggca gcagaaaaac aaaacttaga aagtcaatta gtcagcaagg atgcacaact
      421 acaaagcaaa caaaatgaaa tcaatgtcaa actagatgag atcaaccaaa aaaatgatga
      481 aatcaatcat ctgaatgcag attggacagc aagactacaa gaagcacaag caaaactttc
      541 agaattacaa aatactgtaa atggtttgaa tcaacaaatc gcaacactga cacaagaaaa
      601 aacaaatgta gaaactcagt taacagatac acaaaagaaa ttagacgaag caactgctga
      661 aaactcaagc ttgaaacaat atattcaaaa gttagaaaaa gcaaaagatg aagtggaaga
      721 tacagctgat aaatctcagc aaattgttga agaacatttg cgtaaataat ctttcttaac
      781 aagtaaacct aaattagtaa agaagcaaca gtaatctata ctaagtagtt cagttttgga
      841 gtacaaaatg acaaaatgta cttcaaaatg gactactttt ttcattttaa cttacatacc
      901 aaattacata caaaatgatt tataaaatgc aattgaaaat gataattgaa tgaaaatttg
      961 tgattttgtg gtattatgat aatataactt atagaaaaaa ttgcttattc aactaacggg
     1021 caggataatg agaaaaggtt ttttgataga aataagaaat tagatggtaa attagttaaa
     1081 aaggctgtgt tataaatgaa agtttctttg attgctgcga tggataagaa tagagtgatt
     1141 ggcaaagaga atgacattcc ttggaggatt cccaaggact gggaatatgt taaaaatact
     1201 acaaagggac atccgataat attaggtagg aagaaccttg aatcaatcgg aagagcctta
     1261 cctgacagaa gaaatattat tctgacgaga gataaggggt ttacctttaa tggttgtgaa
     1321 attgttcatt caatagaaga tgtttttgag ttatgtaaaa acgaagaaga aatttttatt
     1381 ttcggaggag aacagattta taatttgttt ttcccttatg ttgagaaaat gtacatcaca
     1441 aaaatacatc atgaattcga aggagatact ttttttccag aagtgaatta tgaggaatgg
     1501 aatgaggtat ttgcccaaaa agggataaag aatgataaaa atccgtataa ctactatttt
     1561 catgtatatg aaagaaaaaa cttattgagt taacgggtgc gttaattgaa gaagaacagt
     1621 aaagataaag cacaagagct tgggattact ccaagctctt tttgtcattt gaaataaatt
     1681 atatctttcc aatcaaattg tttatctgta atccctaatc tttgagcagg tgtcaaaacc
     1741 tttttatccg ctgatttaaa agggcgacaa aagttgtagt aagttcttag aattgtaatc
     1801 gcaaattgag catacttcgg attgaagtta gcgtaaatat agctcttctt atcaccacga
     1861 gctgttgtta atggtctttc aagagatgat atataacgtc ttatctgttg aataaagcta
     1921 ttggtcgaat ggtcattaac atttaatagc atctttgcga tttcgtttgg ttccagagca
     1981 gataaatccg ttctacaatc aactgaataa aatcctttat ccttagtggc taatggatgt
     2041 ttgatagggt tatcggcata tttgcgatat ctttctccat ctttactaat agcctcttcg
     2101 tggaattgat gacttgttag taattcagtt agataatgag atgccaaagt ccgtagaaac
     2161 tttgttttga atcctctgat atctccccaa tcgagcagtt ctgcttttgc ttgtccgaat
     2221 tcttttaagc attgttttct gcttttcgtc ttgttaactt ggcaaataaa atgatgtgca
     2281 tcgctcaacc ttaattcttt cgtgaatact ctataaaagg cgtttctaat agagaagtca
     2341 tcatcactaa tcattcgcca ttcgtcggca ttaaccattt gtttaattaa ccaatagtga
     2401 gcagttgtag tataaggagc atcaacattt aaaccatcga caaatctact cctattagta
     2461 attttcccta attcgtgaag ataagcattc ctattttcgc tatcgttagc ggatggttct
     2521 tgtggataat aagaccaatc taacctatca tttttacgac taaaagtatt gagatggtct
     2581 tctttgaatt ttcttgtatc ttcatttaat tcatccattg aaatattcca atcataggca
     2641 acatcagaac ggaacacata tcttgataag acctcagcag atacaactat atacgtttgc
     2701 atattaaggt cttcaaaccc cgtatatttc tttgaacctt gtcctttctt acggacgtta
     2761 tttaggtagt agtgcatctt gtccgtatta agccacatct cgttaaattt ctttgtttga
     2821 aggggttgtg tctcatatcg ttctaaaaac tccaaacaac gcctatacag ccactccagc
     2881 ttatgatagt aggttccaac tccaattcct aaaatatcac aagtacgact gactgaaacc
     2941 cttccaacaa ccatcttagc gaacattgga agaatggtgt tcttttgttg gtgataagta
     3001 gtggtttctt ctctttttgg tagaacatta gtgaacttct tacacgcctt acattgatag
     3061 cgttgagatt tgcccctact tttccccctt ttgtaaaatt gcttcggctc attgaatggg
     3121 gttgattctt cttccgagca gccttcttta tgaaattgat aatctggctc aacatcttgg
     3181 atgctattga tttctataag gcgtttaatt tcttcaacaa cagaccaatt agataaaggg
     3241 gttactgtac agttttgcga tacacctctg ccaataggat tgtcattgca gtacatacct
     3301 ttatgacctt tatctttgga actaccagtc attttatatc gacttggttt cccttttaca
     3361 tctttgaatt tgtgctgttc tttcccaaaa ttacaacaaa acggattgat gcagtaatta
     3421 tattgaatgg gatattcaga accgttccat ttaaaagacg ttggcaagaa caacattttg
     3481 ttataccttg ttgcaaatcg ttttggagtt aataaatcat attgtttagc cctatctttt
     3541 aattcttcgt ttgaaatcgg aattttaaca tctacaattt catcttcctt cgtggctaat
     3601 cttttaagct tggtcattgt ctatcaaccc actctatctt tgatacccat tttttcaaca
     3661 atccgcttat tacttcgctt gttggcaatc cattcaataa acttcttatc gtctaaaatg
     3721 ttcaataaga attcatccac tgcttcgctt tcagtacgct ctgcatattc agcgtattgc
     3781 ttaactatca cccttacttg ctctgatatt tcccaatcca cagacttagc gttcttattt
     3841 tttggctcaa gaaattgcat aggaaaatgc accccttttt gcttagtaaa ttgtaaccat
     3901 tttaacacac caatttgcat tcctacaata attatttcac gttcgcattt ttatatacat
     3961 tttaacttac attttgtggt gtaaattaac aacaaacgtt gatttaacaa taaaaaacga
     4021 gtatcaaatt cagttgcaat ttgatactca tttaggttta cat
//
LOCUS       DADGHT010000154         3855 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.159, whole genome shotgun sequence.
ACCESSION   DADGHT010000154 DADGHT010000000
VERSION     DADGHT010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.159"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1..1155)
                     /locus_tag="JX887_002705"
     CDS             complement(1..1155)
                     /locus_tag="JX887_002705"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAX1258631.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            1340..3781
                     /locus_tag="JX887_002706"
     CDS             1340..3781
                     /locus_tag="JX887_002706"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAX1258632.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         1231 a          722 c          842 g         1060 t
ORIGIN      
        1 ttatattttg tagtaacgaa tatcattttc gatctttgta atcgaaaaag gtacatctga
       61 agtatattct gcacattctc cgtgttcagg aagcgtctca ctgaaaatcg tttcatattc
      121 gtcaacagtg atccgtgttc gagaatctag catctcttga tgagattgtg cgaagagata
      181 ttcttgatag ttttcttcca gataacctgt aaaaaattca cttactgcac cagaaccgta
      241 gctgaataga ccgatgcgat ctcctggctg tagtgatttc gaattttcca gtagagaagt
      301 tagccccagg tataatgaac cagtgtaaag attaccgatt cgtcggctgt aacggatgct
      361 ttcttcatag cgagccataa gacgttcctg attttcttcg tctgtttggt ctaatacgct
      421 ttgcaatgcc ttttttccca tcttagtata cggaatatgg aaagcaatcg cctgataatc
      481 ttcgagtcct cgacccgaca attctttatg tcgattccaa actttttgga atgattcgat
      541 atacgtagaa ttagataaag gaccatcaac aacaggaaat tcgctataat ctggacgcca
      601 gaaatcatag atatcttctg tcagaaatac gctgtcgtct tcaatcgata aaatacgcgg
      661 gttttgagtg atcatcatcg caacagcacc gacaccttgc gtcacttcac caccgcttgc
      721 caagctgtaa cgagcaatat cacttgctat gactagtact tttcgttctg gatgattttt
      781 gacatattct ttcgccatgt gcaaagctgc ggtgccaccg tagcaagcct cttttacttc
      841 aaaagaacga gcaaaagatt ggattttcag taaatggtgg ataattaccg cactcgcttt
      901 tgaatgatca atcccggatt ctgttccgac gatgaccatg tcgattagct cacggtcttt
      961 ttctgttacg attttgctgg cagcatttgc tcctagtgta atgatgtctt catttgcacg
     1021 attgactgcc atttggtctt gaccaatccc tatatggtat tttgcaggat catccccacg
     1081 gctttctgcc aactctgtca tatctaaata taaattagga ataaaaaagg aaagacgatc
     1141 aatccctatt ttcatttcaa cacctcttta cttatgataa aaaacttact ttactaaggt
     1201 atcataaaaa gattaaaaga aatataaaaa agagaatatt taaggattgt taaaatttaa
     1261 tcttagaaaa aaataactgg aacaagagct atttgttttt acagcaaaga atggtatatt
     1321 tttgtaggag gtggcttact tgaaagaagt cgttatgata gatgctgcaa gaacgccgat
     1381 aggaaagtat cgcggaagtt taagtccatt tactgcagtt gaattaggca cacttgtgac
     1441 taaaggatta ttagataaaa caaaactgaa aaaagataaa atcgatcaag taatatttgg
     1501 aaatgtcctg caagctggta atggtcaaaa tgttgccaga cagattgctt tgaacagcgg
     1561 tctccctgta gatgtcccag caatgacgat caatgaagtt tgcggatctg gtatgaaagc
     1621 agtgatctta gcacgccagc tgatccaatt aggtgaagca gaacttgtga tagccggcgg
     1681 aacagagagt atgtctcaag cacctatgct gaaacagtat cagtcagaaa caaatgaata
     1741 tggtgaacca atttccagta tggtcaacga cggattgact gacgcatttt caaatgcaca
     1801 tatgggatta accgcagaga atgttgcaac acaattttct gtgagcagag aagagcagga
     1861 tcgctatgcc ttgtcgtccc agttgaaagc agcacatgct gtcgaagccg gtgtattttc
     1921 tgaggagatc atcccagtca agatttctga tgaagacgtg ttatctgagg atgaagcagt
     1981 tcgtggaaat agtacattgg aaaaactggg cacgttacgt acagtattct cagaagaagg
     2041 aactgtaaca gcaggaaatg cttccccgtt gaatgacggt gcctctgtgg tgatccttgc
     2101 atccaaagaa tacgcagaaa ataataatct gccttattta gcaaccatca aagaagtagc
     2161 ggaggtcggt attgacccaa gtatcatggg aatcgctcca atcaaagcca ttcaaaaatt
     2221 gacagataga tcaggaatga atttatcaac aatcgatctt tttgagatca atgaagcatt
     2281 tgcagcttct tctatcgtag ttagccaaga actgcagtta gatgaagaaa aggtcaatat
     2341 atatggagga gcaatcgcat taggccatcc aattggtgca agcggtgcac gtatcttgac
     2401 tacattagct tacggattgc ttcgtgaaca gaagagatac ggtattgctt cattatgtat
     2461 tggtggaggt ttaggcttgg cagtcttgtt agaagcgaat atggagcaaa cacataagga
     2521 tgtgcaaaaa aaaaagtttt atcagcttac gccatctgaa cggcgcagtc aattaataga
     2581 aaaaaatgta ttgacacaag aaactgcgtt gatttttcag gaacaaacac tttctgaaga
     2641 gctctccgat cacatgatcg aaaaccaagt gagtgaagtg gaaatcccaa tggggatcgc
     2701 gcagaatttt caaatcaatg gcaagaaaaa atggattccg atggcaacag aggaaccatc
     2761 tgtcattgca gctgcaagta atggtgcaaa aatctgtgga aatatctgcg cagaaacacc
     2821 tcagcggctg atgcgagggc aaatcgttct atcaggaaaa tcggagtatc aagcagtgat
     2881 caatgcagtt aatcatcgaa aagaagagct gattctttgt gcaaatgaaa gttatccttc
     2941 aatcgtgaaa cgcgggggcg gtgttcaaga tatctctact cgggaattca tggggagttt
     3001 ccatgcatac ttatctattg attttttagt ggatgtaaaa gatgcaatgg gcgctaacat
     3061 gatcaactcg attcttgaga gtgtggcaaa caagttacgg gagtggttcc ctgaagaaga
     3121 gattctattc agtattttaa gtaattttgc tacagaatca ttggcttctg cctgttgtga
     3181 aatcccattc gaacgcttag ggagaaacaa agaaatcggt gaacaaattg ccaaaaaaat
     3241 ccaacaggca ggggaatatg cgaagcttga cccttaccgt gcagcaacgc acaacaaagg
     3301 gatcatgaat ggtatagaag ctgtagtggc agctacagga aatgatacac gtgcggttag
     3361 cgcttcgatc cacgcctacg cggcaagaaa tggattatac caaggattaa cagactggca
     3421 gatcaaaggg gataaactag ttggaaaact aacggtgcct ttggctgttg ccacagtagg
     3481 cggagcttcc aatatcctgc caaaagcaaa agcatcttta gctatgttag atattgattc
     3541 agccaaggaa ctagcacaag taattgctgc agtagggtta gctcaaaacc tggctgcttt
     3601 gcgtgcatta gttacagaag gaatccaaaa aggccacatg ggacttcaag ctcgttcatt
     3661 agcgatctca attggggcta ttggtgagga aatcgagcaa gttgcgaaaa aattacgtga
     3721 agcagaaaag atgaaccagc agacagctat acaaatattg gaaaaaatcc gggaaaaata
     3781 aaaaagcaat atctttagaa gaataaagca agatttacag ttattttatt tactgcagat
     3841 cttgcttttt tggct
//
LOCUS       DADGHT010000155         3720 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.160, whole genome shotgun sequence.
ACCESSION   DADGHT010000155 DADGHT010000000
VERSION     DADGHT010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.160"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1682
                     /locus_tag="JX887_002707"
     CDS             <1..1682
                     /locus_tag="JX887_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1258633.1"
                     /translation="IYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETEDFLRM
                     DDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLLFYFVS
                     PYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLKKPINR
                     YSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANSDLRLY
                     FDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKKYPFSY
                     QIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTGKGTAL
                     MIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHLTNLFD
                     DSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVDEEFEK
                     RILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFLFAIPE
                     EMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            1675..2166
                     /locus_tag="JX887_002708"
     CDS             1675..2166
                     /locus_tag="JX887_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAX1258634.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            2154..2708
                     /gene="srlA"
                     /locus_tag="JX887_002709"
     CDS             2154..2708
                     /gene="srlA"
                     /locus_tag="JX887_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAX1258635.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            2726..>3720
                     /locus_tag="JX887_002710"
     CDS             2726..>3720
                     /locus_tag="JX887_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAX1258636.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         1276 a          599 c          765 g         1080 t
ORIGIN      
        1 aaatttatga ttttgatttt tttgatgaga tcatgcaagg aaaattgaaa acagccagtg
       61 atttcaattc ggcatccaaa agaatcgctt atttactaaa taggctgatc gaaacagagg
      121 atttcttacg tatggatgat ttgtctgaag aagtcggtgt cagcagagga acagtggtca
      181 aggatctaaa gacattaaaa gagatgatca atgattttga tgtaaagatt acaggcacac
      241 caaataaagg actaagaata ataggagatg agctagaatt acgactactt ttattttatt
      301 ttgtttctcc ctacttttca gagacgaaaa cagaacagtt tctagaagaa aaacaagcaa
      361 tcaaacattt tcagaagaag acgaatgcta gtaaacaaga aatcaccctt ttaacgaaag
      421 ttatcggtat ttctttgaat agaatctcta gtaactatct gttgaagaag cccatcaatc
      481 gttacagtgg gtgttttgaa tatatccaag aattcaatga actgatcaat cagttggaag
      541 aaatctatga actaactttg agccaatatg aaaaagattt tatcagtttt cctttgaaca
      601 tcatcaacac aagtataacg atgataagga aagctaactc tgatttgcgc ttatatttcg
      661 accccatgat gatgcgtatt cgacgattag atctcattga tctggatgag tccttcttat
      721 atcaagagat gaaacagcac ctctctttat tgataaatcg ggtaattttt cgttatcgat
      781 tgactgattt attttatggt gagatagaaa aaaagtatcc tttttcttac caaatcgcta
      841 gcgaatgcat acaagcatta gaagctatct tgcaacataa gatctctaaa gtagagatca
      901 gctacctaac gttgtatttg gagttagcat ttcgatatca aaaagagcat ttttcctcta
      961 aaaaagtagc cattgttcat acgacaggaa aaggaacagc attaatgatc caaagacaaa
     1021 tcaaaaggat attggggagg gatatacaaa taacacatgt ttcagaagaa caatatgaaa
     1081 aagtagatct aaacaaatat ttcgctgttt ttacaacgat tccgttaaaa aatgtaaatg
     1141 aagagacacc ggtgatccat ttgactaatc tttttgatga ctcttggtta agggcacaat
     1201 ggcaaaaagc aaaaaaaaag cgattagccg ggtttcattc tactgttttt ttctatcaaa
     1261 tatggaaaga aaaaaagacg tatcaagaat atttaaacaa attagtcgct cctttgatca
     1321 gaggctatta tgtggatgaa gaatttgaaa aaaggatctt gaaaagagaa tatcagcaaa
     1381 gcacatttgt taacaaagaa tttgcttttc ctcacacaac caaccagcta tctcaacaca
     1441 ttgttttatc agtagggcta ataactgatc aaggtttagc agaaacagga ggaaatggag
     1501 ttattttttt atttgccata cctgaagaaa tgacggctga agttgagaat gaattatttg
     1561 agctatacga tatcctattt gaactcataa aaatgggaat agatgagttt attgaattag
     1621 caccgacaca agaatcattt ttaaaactaa tcaaaagtaa aggagagaga cttcatgaat
     1681 gatatgtatc tattcatagt tttcgcagct tcagcttatg tgctgcaagc agttatcagt
     1741 tggaagcaac taaagcattt caatcaaaca tatagcgaac tgcgaagaaa aggaaaagta
     1801 gcgattggta aacgacctgg gaaaatccgt tcaggcacga ttgttatgct agctatagac
     1861 gatcatgatc aagttttaga agtcagaaaa atgcaagggg ttacatcttt ggcaaaattt
     1921 cattcattac ctgtctatgc gggtgaagat atccattaca tcgatcgtta ccatccctca
     1981 gttcgagcgg aagatcgttt gacacaagca gctttagaaa atgccagaga agtatactta
     2041 cgaatagagg caggaaatga aaaaagtgaa caaccttcat tgccttttat tgctatgctc
     2101 aataattttc ggatatggaa aagtacgatc aaagaaaaaa ggagtgacaa acgatggata
     2161 tcataacaaa atttgctgag ggatttatga ggctgttcca aacaggtgca gaaacattca
     2221 taagctggat gacaggaatc gtaccagttg tcttgatgct gatggttgca atgaatacgc
     2281 tgattgcttt tttaggtgaa gaccgagtaa cgaaagtagc caaattatca gcgaaaaatc
     2341 cgcttactcg ttaccttgtg ttaccgttct tatctgcttt tatgttggga aatcctatgt
     2401 catttacaat ggctcgtttc cttccagaat actacaaacc aagctattat gctgctcaag
     2461 ctcaattttg tcatacgagc aatggtgtat tcccccatat taatcctgga gaattgtttg
     2521 tatggatggg gattgctcaa gggatcgaaa ccttagggct aaattcgatg gagctggcta
     2581 tccgatactt gcttgtggga ctgctgatga actttattgg tggttggata actgatttta
     2641 ctactggatt tgtatgcaga cagcaaggaa tcgttcttag caaaaaagta gagctttcag
     2701 ttgattagag aaaggagagt tttaaatgta tggtgatatt aagatcgtaa gaggaaacgg
     2761 cgggtatgga ggtcctttga ttattaggcc gacaaaagat aaacacaagt tcatctatgt
     2821 cacaggtgga ggtgagaggc caatgatcgt agataaaata gaagaactga caggtatgga
     2881 gtctatcaat gggttcaaaa catcaatacc tgatagtgaa atcgcgcttg caatcgttga
     2941 ctgtggaggg actcttagat gtggaattta tcctaaaaaa gggataccaa ccatcaatat
     3001 cgtttccaca ggaaaaagtg gcccattagc acaatatatc actgaagata tttatgtttc
     3061 agcagtaggg ttagaacaaa tacagccact aatggaaact gatgataaca aagaaacagt
     3121 aaatactgca tctccagata aaaagtacaa atatgatact tctaaaaaga taaccgagca
     3181 aaaagcagag cagcaaaact ggatagcaaa aattggaatg ggcgcgggaa aagtagttgc
     3241 tacattcaat caatcagcaa gagaagcagt agatacgatg atccggacag tgatcccttt
     3301 tatggctttc gtttcccttt tgattggtgt gatacaaggt tctgggatcg gtaatgtatt
     3361 tgctaacatt atggcacctt tagcaggaaa tgcagttgga ttaacaatca ttggctttat
     3421 ttgttcactg ccatttttat ctcctttgct tggtccaggg gcagttatta gccaagtgat
     3481 tggaacattg atcggtgtag agattgggaa aggaaatatt cctccccaat tagcattacc
     3541 ggcactattt gctatcaata ctcaaaatgc atgtgatttt attccagtcg gtctaggttt
     3601 ggaagaagca aaagctgaga cagtagaagt aggtgtacca tcagttcttt attcaagatt
     3661 tcttaacggc atcccacgag ttatcattgc ttgggtagca agttttggat tatatagctg
//
LOCUS       DADGHT010000156         3719 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.161, whole genome shotgun sequence.
ACCESSION   DADGHT010000156 DADGHT010000000
VERSION     DADGHT010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.161"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..354)
                     /locus_tag="JX887_002711"
     CDS             complement(<1..354)
                     /locus_tag="JX887_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258637.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRTF"
     gene            complement(614..1162)
                     /locus_tag="JX887_002712"
     CDS             complement(614..1162)
                     /locus_tag="JX887_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258638.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1163..2020)
                     /locus_tag="JX887_002713"
     CDS             complement(1163..2020)
                     /locus_tag="JX887_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAX1258639.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2306..2592)
                     /locus_tag="JX887_002714"
                     /pseudo
     CDS             complement(2306..2592)
                     /locus_tag="JX887_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2582..2911)
                     /locus_tag="JX887_002715"
     CDS             complement(2582..2911)
                     /locus_tag="JX887_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAX1258640.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2988..3260)
                     /locus_tag="JX887_002716"
     CDS             complement(2988..3260)
                     /locus_tag="JX887_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAX1258641.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3260..3523)
                     /locus_tag="JX887_002717"
     CDS             complement(3260..3523)
                     /locus_tag="JX887_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAX1258642.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
BASE COUNT         1092 a          754 c          473 g         1400 t
ORIGIN      
        1 aaatgttctt actgcctctt ccacactaat ttcttcgttc aatttcacta ataatacttg
       61 atctcgctta ttataatcgc tttcatttat cctaagagtc aaatcttttt ccaccataac
      121 ttttacaccc aataaatttt gcggtttatt tttctctgtt gaaattcttt gtgtagcctt
      181 taaactgaca attagctcat tgggtacata ctctatttga gagtcatcta attggctcat
      241 aatcctttct ttttggttag tatctgcagt tacttgttta gtatgagcca tgaacccaaa
      301 catactcacc ccaacaacca atcctaaata tattttcttt ttaaactttt tcatctacat
      361 ctcctcctaa tagttttatt ttagagttag ctctattact tatttactaa ctcaacaaca
      421 gattatcata cacttgttaa tgaaatcaca atatctcatt aaaacacacc ctaaaatcat
      481 aaccgttcct atgctcattt tttggatttt ttaatcacgt aaccagaaaa ataaatcccc
      541 tctatttcac gcaaatcaaa gaagaactaa gtaactaccg tttaaaggta gttacttagt
      601 tcttctttga ttattatcta actttattat tcattcccca ccctttgcgc agtgagtctt
      661 cggtatcttg ttttatctga ctggtagttc ttattatttc tccacgatca tctaattctg
      721 gaacaattgg atatttttct ctgaacaagt ctagttcttt caccacgtca ttaaacaaat
      781 cttgcttatc ttcttgcgta agattctgtt taatatactc atctaaagct tttctaagca
      841 attcatctct tgtcatatta gtctcatact tttctactaa aactctggaa gtcgcattta
      901 acaaagtcga cagttttaaa ggatgcttgg tggaataaac cttatcaaac tttctgattg
      961 gtgcgccaac tttttttgtt cttcctctac tctgtctttc aacattggag gaagttttta
     1021 tttcttgaac ttggtgcact tctaattgct tattttcaga tggtgtaatt gcttgctgct
     1081 ttttctttgc ttctgcttct ttttttattt tggcgagtcc tttgttgttc ccaaaaatat
     1141 caagtccttt gatgtcagcc aattactcca cctccgcata ccaattctcg tgttcttcca
     1201 attctttcaa aatactgata aataattcgt ggcttttgcg atcccattgt tttaagagac
     1261 ctttctttgt cttctccatc gtaatacctg atccgtcgta tcgttttaag cgcgcatttt
     1321 tgagtacaac atttttaatc aaatgttccc cataaatctc ttgggcttgt ttatacattt
     1381 cctgatctac tgcgtcaccg ctttccaaca tgaaaggaat aacaccagca acatataaat
     1441 ttgtatcaaa ttctttcaca aaaaagtcca tatactcaag atattgcatc gcatttctca
     1501 tcgattttac ttgggtctgt aagacgacga ttgcccaatc cgcaatgtac atcgcggatt
     1561 tactatatac agaaatagaa ggtgggacat ctaaatagat gacgtcaaac tcatcaaata
     1621 atggttctag cttttctttc atatatttga attgggataa tgaatcatta tattggtctt
     1681 tgatccaatc atcatacatt tcaaaggaca tgtctgctgg aagtatatag aggttattga
     1741 ttactttata gacagcctct ttaggtggaa gattgtttat caacacgtca gtcacagtat
     1801 tttcgtaaac aatcggttca ccttctccgc ctccttcttc gttagtgaag ttcatatgcg
     1861 ttaagttcat cacatcagaa gtatttcctt gcatatccaa gtcaattatc aaggttcttt
     1921 ttccttcatt aactgctgat tcaaacccta acatttgcgc gcacgtactt ttacctacgc
     1981 cacctttaaa attaccgatt acatatttct tcgctaccac gttcctacct cttttctttt
     2041 agcaatattc atttgatact attataacat atttattttt agttactacc aaaaaaaaga
     2101 tatatatgta ctaccttata attaataagt aaaaggtagt acataaataa ggaaaagctg
     2161 aaatatattg atttatagct ttcctcaaag taatgacgtt atttaattta tcgagaagca
     2221 gagaatactc gcgactttag tcatgtagac gaatcagatt ttcgataaaa aagaagccgt
     2281 ccttcttaag aacgacaaca aatcactaga ttaatttttt caactgttca taaaagtttt
     2341 catgcgttcc acataacaat actggaataa ccttgttttc tataatctcg taagctactc
     2401 tatatgttgt gcccgcatat ttgaacccac tagaccaaat acctgataaa tccccagttt
     2461 tttgttcacc cttatatgga tcaatcgcaa tttcatcata aattaaattc aaaaattttt
     2521 ctttcaatgg cttctctttt agctttttaa atacttaatg acatgttttg aaggaacgat
     2581 ttcataagcc aatttctgtt gccaactcct ctttagtcat tactttagaa ttagtaagtg
     2641 tatcttcagc aatatctcta aaggaagaat gcattttgtt ttttctattc ttaaattcta
     2701 caagaatctc atctttatcg tagccttctg caattatatc agacaaaata tcttcgctaa
     2761 aatcataaaa ttctttttgt ggttcaacaa attcataaag aataccattc tctaccaact
     2821 ttgcttcaac ttcgactcca ttaggaacat taaaatcttt aggtactgtc aacatgattg
     2881 aattgccttg ttttcttgtt tttgtaatca tttaaatccc tcatttctaa cagtatgtaa
     2941 ttacttagta aatacattat accacgagat aatgtattta caagtaatta ctgtgactcg
     3001 taatgcgtcc ttgctgaata aatttcaacc acgtgttcat cttcatctac cttataaaca
     3061 acccggtgtt gtctattcaa tcttctagaa tacctacctt catgtgtagg ttttaacttc
     3121 tcaaatgatt gggtagggag atagggatct tcctttaaag tctgaataac cttctcaaat
     3181 tgaggtttca aattagactg tttgattttc tttaaatcag ctttagccga gtttttaatc
     3241 atcacagaat agttattcat tataagttat cccaatcaat ttcatcaaca ttagtaaatc
     3301 cactatcatc tttttctcgc ttacgaacaa cacccaaagt gcctatttgc tcaagtaata
     3361 gcgtttcttt gattgctttc caatcatcca aaccaataag caccgcatta ttttcactgc
     3421 gctcactaat gatttcaatt tccgtatgat tctcatttac atctttcaac aacttataaa
     3481 aatttttccg tgctgagcta ggatttaaga ctgtttttgc catatctact ccccctctaa
     3541 tttatatctc cattctaacg tacttaatta agtacgtaaa ttcgattgtt ttgtttaaat
     3601 tggagtacca aaacagcatt gtaaagtgtt atccgtttcc tttatacccg tggtgctagt
     3661 taattttttc ctagaggaaa atgtctaaac atgttggtaa atcaacaaaa aaacgcata
//
LOCUS       DADGHT010000157         3532 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.162, whole genome shotgun sequence.
ACCESSION   DADGHT010000157 DADGHT010000000
VERSION     DADGHT010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.162"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(83..1162)
                     /gene="uxuA"
                     /locus_tag="JX887_002718"
     CDS             complement(83..1162)
                     /gene="uxuA"
                     /locus_tag="JX887_002718"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAX1258643.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPACEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(1165..2796)
                     /locus_tag="JX887_002719"
     CDS             complement(1165..2796)
                     /locus_tag="JX887_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAX1258644.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            3100..>3532
                     /locus_tag="JX887_002720"
     CDS             3100..>3532
                     /locus_tag="JX887_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1258645.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAERE"
BASE COUNT         1131 a          702 c          485 g         1214 t
ORIGIN      
        1 taaaaacata tttaaacact cctttccttc cgttagtttt tagaagagaa aatttttcct
       61 ctaaataaac tcccttatat aattatttac tcgccccctt ttcaagcgct tcccaaatac
      121 catttaaata aactgcacct agagctcggt catataatcc ataaccaggt ctaccggttt
      181 ctccccaaat catccgacca tgatctggac gaatatagcc attaaatcca ttatcgtaca
      241 ttgtttttaa tatcttatac atatctagag aaccatattc tgatttatgc ggcgcttcgt
      301 aaaaatcgag tccattgtca cttaaatatt tgatattacg aacatgtgca aaaggaatcc
      361 gatcccgttg acaaaattca gatagaattt catagacatc attatctggt cgttctgcaa
      421 tacttccagt acataatgta ataccattag aaggagaatc cactacatta cacaaccaat
      481 ctaaatcgtc acgattttta acaatacgag gtaatccgaa aatggaatat ggtggatcat
      541 ctgggtgaac tgccatttta atcccaactt cttcacatgc cgggataatt gctttgagaa
      601 aatatgcaaa gttctctcgt aatttctctt catcaacttc tttataggct tctaataatt
      661 gcttaatttg tgataaccga tgaggttccc aacccggcaa ttcaaaatta ttagtagaat
      721 tttctacttc tctaataatt tcctccggat cagtagggat attttttgaa atataggcta
      781 acgtagaaga cccatcatct aaacgataat ccaaatccga ttttacccaa tcaaatactg
      841 gcataaaatt ataacagata acctcaatcc caaattctgc caaattgcga atcgtctgtt
      901 tataattctc aatgtattga tctcgtgttg gtaaaccaat tttgatatca tcatgaacat
      961 taacactctc aataactttc aaggtaagtc cattggcttc gacttcatct tttaaagatt
     1021 taattcgttc tctcggccaa acctctccgg ctggtatatc cattaatgtt ccaacaattc
     1081 ctttcattgc tgggatctga cgaatttctt gtagtgagat tttttcttca tttgccccat
     1141 accatctaaa agtcatttcc atagttactt tcctccaact tctgttatat atttattgat
     1201 tgttttacga actgcttgag gacctactag catttcgcaa aagatttttt cagttttctt
     1261 tcctacccca acttgatata aatctaaacc aaagatttct ttattttcta aaatttcctg
     1321 taccgcacaa tgaatctttg aaggatcttg ttcacctaat ttcaatactg ataatttatc
     1381 ctgcaactct accaataacg gatcaggact tggcacaaaa ttttcccctt gatcatcgac
     1441 tgccagtaaa taacgtaacc aagcagcaat agcgatagga ataaatgtta gattttctgc
     1501 atttccgtct ttttcgacat actttttaat tgtttcacca tagcgaatcg ctactttttg
     1561 agaagtatct gttgcaattc gttgtggtgt atctggaata tagggattag gcaaacgttt
     1621 attaattact tcatcaataa attgttttgg atcaataatg cctggatttt caactactgg
     1681 taaaccttct aaataaccta ttcctttgat taaaccaacc aaatcatcat cctgcatctc
     1741 tgctgaaatt gattgatatc ctagcagaca acctgttact gccaaagcag tatgaagtgg
     1801 attcaagctt gtcgtaacct tcatgatgtc tgctttatca accgtctctc tatctgtcat
     1861 aatcacacca gccttttcca atttaggccg gccatttgga aaactatctt caataactaa
     1921 ataatgaact acctcagtat tagtgaaagc agcaatattg gtatgttttt ttgtgtgaat
     1981 gatatctaaa tcctcgagcc ccatcatcaa tagatcttcc tttacattct ctgaaggatt
     2041 tggcgtaatt cgatcaatca tactccaagg aaaagtcact ttttctttat cctttaaata
     2101 agcaataaat ttttcagaaa catatccttc tttttgccaa gcttctgcaa tcgtaaaaat
     2161 actatcttga aaacgttgac cattctgtga gaaattatca gtagaaacca tcgcaatcgg
     2221 caactctcca gcattaaatc tgctatataa caaggatgtt acaatactca tcgtatgttg
     2281 aggattgcta ggtccagatt tgatatcagc tttgactacc gaaaagaatt gccctttaga
     2341 atcttttaaa ctgtaacctt tttcagtaat agtaaacgtt gtaaactgta atttaggatc
     2401 ttcaaaatat ttaaccactc tttgatagtc cgctatattc ttcggattgc aatataaact
     2461 atcagccgtt actgccaaaa gtcttttttt gagttcacca tctccactca taacaatttc
     2521 caaaatgtca ttgttatagt catgataagc tttttccact acttcttcat caaatgtttc
     2581 acacacaact actcctgttt ctaattcatt ttgatctgct aagcattgag caatttctgc
     2641 atgaaatcct cgataaagat ttcctccacc aaaatgaagc catactggat gttgctggcc
     2701 ttcttgctta acttctttga catcaaaaca cggcagtaga atctgcattt cattgaattc
     2761 ttcgatagaa ttttgccaat ttttaatcga aaccataatt aacctcctca aactgatatg
     2821 ttagttttga tacattttat attttaaaac ccattgtaac cgttgtcaat ataaaaaggg
     2881 aataaacttg cttttttcta ccatatcaga atgattgtat tttttattca gaaaaataaa
     2941 atactccttc tttttggact gattttatcg aaacttattt tttctttttt tcatgtattc
     3001 ttttattttt ataactagtg tattacttca aaatttgata ttatatggca tgaacagaat
     3061 taaaatatca gttaaaataa aagttaagga gcattgtgta tgacaattaa aactagtctc
     3121 caaaatcaag cttaccaatc tattcgccga caaattatct atgctgactt agaacctgga
     3181 aaaaaagtat cagaaaaaaa attagaagaa acactttcta ttggtcgtac accaatacgt
     3241 gaagcactga ttcaactccg acaacaaggt cttgttgata caattcctca aagcggaaat
     3301 tatatctcat taattgattt agattcggcc aaaaatgctc gatttgtcag agaacatttg
     3361 gaacgacaaa ttatgttaga gtgttgtgcc aaaatgaata accaaaaaaa acggatttta
     3421 gaaactataa tttcagaaca agaaaaagct gttagtcaaa aaaatgctcg tagttttttt
     3481 cataatgata atttattcca taaagcttgt tttgaaattg cagagcgaga ag
//
LOCUS       DADGHT010000158         3520 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.163, whole genome shotgun sequence.
ACCESSION   DADGHT010000158 DADGHT010000000
VERSION     DADGHT010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.163"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(258..962)
                     /locus_tag="JX887_002721"
     CDS             complement(258..962)
                     /locus_tag="JX887_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258646.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(1149..1394)
                     /locus_tag="JX887_002722"
     CDS             complement(1149..1394)
                     /locus_tag="JX887_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258647.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(1411..2262)
                     /locus_tag="JX887_002723"
     CDS             complement(1411..2262)
                     /locus_tag="JX887_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAX1258648.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            2428..3432
                     /locus_tag="JX887_002724"
     CDS             2428..3432
                     /locus_tag="JX887_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAX1258649.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT         1092 a          601 c          683 g         1144 t
ORIGIN      
        1 ctatcagaaa atatgtttat tattagaatt ttttatagtt aaggttaggc atcttaagaa
       61 atcaggcaac tccaagatat cttcaggtag aagagaagtc gcctaacatt gtaggatcat
      121 aggtgatttg ttggacaggt caagctgata tttgagcctg atgttagaag gaatttcttt
      181 ttacttgctg tagaaattat tatatgacta aaaaggctgg gattttaaat cccagccttt
      241 tatgacaaat agaattttta tcgatcagta atcgctgtcg ctgcaaattg ttcgatcaaa
      301 ggaatcaaag tcaatttgac tttgtatttc cgttcgagtg ctttttcgat aacgaactca
      361 ttttcagtag tcatagaaat agttgctaat ttacgaggtt catcagcatt tttttcatta
      421 ataactactt catgttcatt ttgttctgtg taaaatttag gatactcagc aacggctttt
      481 gaaaaatcag caaaacttaa agcggcattc gtatcagttg agcgtgtatt ttcagttgtg
      541 tccgcttttg gtttttccgt tttttcttct ggcacactga ctgtttcttc tgtaactggt
      601 gtcgcaacag cttgcgcagt tggttcatcg tttttcaatc gttgatcatt ccagtaagac
      661 acgatttcaa taagaagatt gtcacggaat cgttcgaaaa tcccgttttc tcctgaacga
      721 attctcttta atacagtatt gaagttgtca tcgattggca cgttgatccg tgtatcttca
      781 tttgttttcc cagctaatcc gatcgttaag atttgacggt ttttgggatc aagcatgact
      841 tgtaacggca aaccataacg tcgcaagctc tcttcttcta gagaacggaa taattgtcct
      901 cttacaccat ccaatgaagg acggaattga tttaataatt tttgtttctg ttttttcttc
      961 atatgttctc tccttcgctc ataccctttc gattataaga aaaaaacagc caaatgaaaa
     1021 ggagtaatgc aaaaaaactt gcgtatacgc aaattacaac agaaaaattt gcgtattttc
     1081 ccgttttttg aaagaaaaat aaaaaatgga acggattatg tatatataca taatccgttc
     1141 cattctttct attttttcgg tatcaaggca aaaacaggta gttcaggtga ataaatgact
     1201 tcatgttcgt gccagggttt gaccattagc gaatgatcga accgtttttt cagttcttcg
     1261 atgatttgat catgtgtcca gtttcttgca ggaaaatgtt ggattttctc tgcatcgatc
     1321 aaaaagacaa aatcggaatg aaaagtctgg gtaacttctt ccgagagaga attcaagcgt
     1381 tcgattggat ccataaaatc acctttcgac ttaaaattgg gtagtatctg ggtcttttgc
     1441 tttgccgact acaccatcta actgatcgat ttgtttcatt tcttcttctg ttaattcaaa
     1501 atcaaataat tcagtatttt ctttgattct gcttggtgtc actgacttag gaagaggaag
     1561 gaattcgtgt tgcagcgacc aacgcaaagc aacttgtgca atcgtcttgt catgtgcttc
     1621 agcgatttgt ttcatttcag gcacatcgaa gattttacca gtgcctaatg gactatatgc
     1681 ttcgaggatc atatcatgtt tttttgcata ctcaactaca gttgtctgta attcgcctgg
     1741 tgcaaggaaa acttgattga ccatcggcat aatttttgct gtttttgcta gtgtatctag
     1801 atggtggggt aagaaattgc tcacaccgat tgctttgatt ttacctgctt catacagttc
     1861 ttcaaatgct cgccatgtat ctgcatttgc ttgttcccaa ttatcacgaa aagcaacagg
     1921 gtttggccag tggatcaaaa acagatctaa ataatctgtt tggagcttct tcaatgattc
     1981 ttcaaaagaa gacatcacaa gttcatagct gtggtttgca ttccataatt ttgttgtcaa
     2041 gaatatctct tctctaggaa ttccactttc cttaatcgct tggccgacgc tttcttcatt
     2101 cttgtatcct tgggcagtat cgatatggcg ataacctgca gccagcgctt ctttaacaga
     2161 ggaaacagcg acatccccat caggtgtttg ccatgtgccg aatcctacta ccgggatttc
     2221 gtaaccattt gatagacgat aagtgcttgt taatgaattc atactttcag ctcctttttt
     2281 attcgttcaa ctataagtgt agcgcatttt tcgaaaaaaa gaatccattt tgtttctact
     2341 cttgaaattt ttgtttaaaa gaaaatgatt ttgattctgg tatttttgat tttttttccg
     2401 taaactaaga cagaagggaa tgagaaaatg gatatctatt taaaaaaagc aattctgcat
     2461 attattgaca gagaaactgg ttctccagtc ttttcacaaa aagagctgga tctgacaaaa
     2521 gaatatattc gtgattttct tcaaaagaag atccaaaaaa tctcttctgc tcaaacaaaa
     2581 actggacaac tagcagaaga aagcatgatc gttgaatcac ttaaaatcgc tcaagaaaat
     2641 tttgtggaag caagtgaagc aatcgttcag cggtggttcg atatctacca agaaagtgaa
     2701 gaagcaccta gtgcagatgt atttgttgtc ttgtatgaat tagatacagt gatgtactta
     2761 tctttattga aagtcaatta tcgtgaggct tacactcact ttgttgaagc agacgaagca
     2821 gggatcgaca accgcttgat tttgaatcga gcaattctag gggcgaaaac acaaaaagca
     2881 gatgaagcat tcgctgtgaa tttgactgat tggacctacg aattaattga aaaaaaatat
     2941 gagttttctg gcaaaaaaga gctttatttt tctggaagag tgatcgaaag tgttcctgca
     3001 ccttctttag aagaaaatgt aaaagtgatc caaaaagtag ccaagcatct tggaaaaaaa
     3061 tttgagacag aagaatttga tatcatggct gatttgaaag aagctgtcta tgatacgata
     3121 gaagaaaaag gtcggttgga tcatgagatg attgcggaaa aagtcttcaa ggaaaacatc
     3181 acggcaaaaa tggcttttaa agaagaagta caagagcaag gatttgtccc agaagcacct
     3241 cctgtaaaag aagtacaaga aatttctgag aaaaaatttg gaaaacaaaa attcaagcta
     3301 tcaaacggga tcgaactgat cgtaccagta gatgtatatc gcaacccaga tttgattgaa
     3361 tttgtgaata atccggatgg tacgatatcc gtgatgatca aaaatgtgga tgaagtattg
     3421 aatcgtttat aaaaatgact agaatattag gtgttcaagt accagtgatc agttaaatga
     3481 attgtgtcaa gagaaggatc ggaaaagacg aatataacaa
//
LOCUS       DADGHT010000159         3415 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.164, whole genome shotgun sequence.
ACCESSION   DADGHT010000159 DADGHT010000000
VERSION     DADGHT010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.164"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..2199)
                     /locus_tag="JX887_002725"
     CDS             complement(<1..2199)
                     /locus_tag="JX887_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258650.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESLSESFNEARSSEPSITQESQIER
                     QEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVRVPRASIGLIEF
                     IRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITFEVAFFQSGGTE
                     PNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGNLGNLLIDGQDV
                     TNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREPISGGVRIAEVT
                     NPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYALEVTDVDLFNE
                     GRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNVINLNENELTYT
                     LHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRFSANNTIGGPTS
                     FTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKVIKTDENGQRLA
                     GAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYLLDATVHDVFIN
                     EYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGETLQTG"
     gene            complement(2871..3139)
                     /locus_tag="JX887_002726"
                     /pseudo
     CDS             complement(2871..3139)
                     /locus_tag="JX887_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          956 a          757 c          543 g         1159 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tacattaaaa gactcacttg tgctttcttc tggtacactg atttctattg agaccgtatt
     1861 tgattgaata tcaccgcttc ttgcggtcaa ttcgtattta cctgaatgct gggaagaata
     1921 agtaatcaga cgttcgtaat cattgagttg cttcacttcc ccttcaatca aatcctcact
     1981 cttatcaatg accaatgcat ttagcaggtc tggtgttcct ctgactcgca actggaactg
     2041 ctcacccaaa gcagcctcct cttgatcaac ttcgatcgtc agcgaacgct ctggctgttc
     2101 tgctaaagac tcagctagaa ccgttatgtt cccaaattga ttgatcacaa taagcataac
     2161 tagaaacata cttaacagtt tatgaaattt gttcctcact attactcccc cttataattt
     2221 tgactaaaca acaaggtacc cgataatttt ctaaaaagat tccccaactc aaaatggctg
     2281 cgttacctcc ctcgtatttt cggttcaact caagcgttgc aatgtaagct gtaaacaaag
     2341 ctaatgattg ccgattgtct tctgttgatt gattcgatag ctttgtatga cttttagttg
     2401 tccgtgtggc ttaaccataa ttatgatttc acgattcctc ctgccagtgc cttgcacaag
     2461 ctggagcgta accctaatag ttattttgtt aatgtactta tatactttta tacttttcca
     2521 ttagaaacaa tcactaaatc gttgatacca aggtcagact ctagaatttc atcagtgagt
     2581 ccctgtattg gttaaccttc atcaatccca aaaaaatata tcaatgctta gcatcaaaat
     2641 gaatatatag tttagaatac ttgggattca tcgataactg atcgcttatt tggccatatt
     2701 atttggcact tggttcaact aaacgcattt aggatgttcc ttcattctcg tcatggatgt
     2761 tctcaaaccg tcattactaa taaactgtcc accgaatcga tggttcattt cttgcatttt
     2821 ccacgtccaa ttactctttt tgctctttat ttgggcgtag tttcactttc ttaacttgta
     2881 tcgtcttcca tcaactcctt aatcatcttc ttagctttat tggctcggtt tccttgtaaa
     2941 aggtatctac aaatagtgac aatctgtatt aaatcttcat cattttctgt aatgtcaata
     3001 atttctatat tctgtaccat atattgcaaa gggtttcact aagttcataa ccgaagcgaa
     3061 ttaaacaact tttgtataga ataactacct tttctatttt tccattggta attctatcta
     3121 ttaattggtt taatcctttt gttgtagttg attccactac caagatgatt ctctcgaatt
     3181 ttaaagcttg aagatgtatt gctatttttg ctaactggcg tatttgcaac tatttttccc
     3241 ttctattctt ccttcattga ttcccctcta aaattactat ccataaaaaa ttgcataaat
     3301 gacaatagta tttatattag tcatactgct ttttaacaca gcaaattcca gaaaaacatt
     3361 cgttacatat ttgtgaattt ttccaaaaaa taacattttt ataaaacgac gaaaa
//
LOCUS       DADGHT010000160         3397 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.165, whole genome shotgun sequence.
ACCESSION   DADGHT010000160 DADGHT010000000
VERSION     DADGHT010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.165"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            150..1190
                     /locus_tag="JX887_002727"
     CDS             150..1190
                     /locus_tag="JX887_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAX1258651.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            2014..2346
                     /locus_tag="JX887_002728"
     CDS             2014..2346
                     /locus_tag="JX887_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAX1258652.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            2965..3306
                     /locus_tag="JX887_002729"
     CDS             2965..3306
                     /locus_tag="JX887_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAX1258653.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1263 a          460 c          644 g         1030 t
ORIGIN      
        1 agtacataat tcattttatt tctgatttta ggtagtattt aattaaaaaa cagttttaat
       61 gcgtttgcat tttttattta tctttgctat tttcgaaaag agtaggtaat tttacataaa
      121 taaaacaacg tgaaagtaga ggatctacaa tgactgattt taaatttttt aaggcggata
      181 gagtttacaa cgaattattt tatcaatttc caaaagtctt tattgtttct gacgaataca
      241 aaaaaatgaa agattcaact aagattgcct atatgctttt aaaagcaaga ttagagatcg
      301 caatcagcaa acggcaaatc gatgaagaag gtaatgttta ttttacttat acgacaaatg
      361 aactatgtag agtattaaac tgccaaaaac aaaaagcgat agcaatcaaa aaagagttgg
      421 aatcctttgg tttattatta caaaagcaga tgggatttaa caaacagtta gggaaaaata
      481 atcctaatag actatatcta gcagaattaa aagtctcaga aaatgatatc tacttactcg
      541 aaaaatttga tagagagaat agggaaaacg ttgataaatc agagggtatg aaaatcatac
      601 ccaccctcga cgaaaaatca gacgctgaat cccttggggc tcaagagggt atgaaaatca
      661 taccgtgcca aaacgttgat aaatcagagg gtatgaaaat cataccagaa cttaataata
      721 atatattaga cactaataga cacaatatag acactgaaaa agaccgccta caagatcaat
      781 tgttgttaga caattttgag acaattatga caaacgacag cattgctacg tttgtccctg
      841 aacgagtatt aaatttgata aaaacatttt cttcaagtta cagtgaagct caaaaaaccg
      901 tccagactat tcataatgca aagaaaaaag ctgaaataga aagtgatatt tcgatagttt
      961 ttgaagaact cgatagttat tatgtcaatg cagaacaaga attatacacg acactgttaa
     1021 aagcctatca aaaattaaaa accgaaaaag tcgaaaatat ccagaacctg atttttgtct
     1081 atgtaaaaaa ttggtttatc gaaaaaccaa tagctgctaa agtatcaagt gaaaaacgtt
     1141 tgaattatgc aagctcccca agcactatta cgaaagactg gttagagtga aactttactg
     1201 acaaagtgat tgttgcttca tggagtaaca ttaaaattaa aaatttttta ttattctaat
     1261 tatattacga atattacaaa ataatagcta ttttaataga atttataagt taaaatatta
     1321 tgataaaaat cacaaacgta gccttttacg tcataagtgt taaaagaaat aattaatttc
     1381 aaatatagaa aagggaacgt atgtttgcat actccttttt tttgagttat aataatacgc
     1441 gaagagagat aatttcatta tttaaacaag ctaaaaatct tgatattact tcttttcagg
     1501 caatacgaat attattcgct tacatttttt gtataaattt aattgtctgc tatgcttgtg
     1561 atgaattgat tttcgttttg cacttttgga tgataaattt ggacaattga aaatacaaaa
     1621 aaaagaaagg cggtatgaac tcggaaggct ggtaaccttc gtcagcgttc atacacggca
     1681 ttaagatttg gcccttaatg cgttaacctt tcagtgttac ggtattaccc gcaatggatt
     1741 tagtataaca gatattcaaa agtgatacca ctttttttgg ctgtgttaag gttaaaaata
     1801 cgtgatatta cgatgaatct atgcctaagc ataatgttat aaaaatgtcc gtgtggctct
     1861 ttgccgtatg acgaacgctg aaattagagg gaacgcatgt ttggatgcgt tccctctttt
     1921 ttgtttgtca tgaacgaaaa tcaattctct atttttgaaa aataacaaga aaaacttgtt
     1981 aaaaatattt aaagaaattg ggtggtttat tttatgtcat atacaggaat tttgagtctc
     2041 aaagatattt gtcactacgg taaacggtgt accgctacag agaaaatcac gaagaaacta
     2101 tcaactggcc aaagtaaaac cgttgtgcag tgtaagaaat atataatcca gaaagacaaa
     2161 gtctcagagg aaatgattta ttacattggg aaacaaaagc aaataatttt aaaagatcct
     2221 atccccttaa aagagctata tccaacaatc aaacatgttt atgaccaaaa cggtgtactg
     2281 attggtcgaa gaaaaaatgg agtcttgcgt tgtaccgcaa aagggatggg gcgtttgatc
     2341 ggctgaattg atcattctca taacttgtat tttatcgttt ttcgcttgct tgaaaatatt
     2401 gtcgagactt ctaaaggaac ttagagtcac tagaaaaata aggagtagac ttgatctatc
     2461 aacaattccc ttcggggagt gacggggtag gttttaacga ttggtaacgt aaaaaattgg
     2521 tcaatcgagt aaatgcgctt gtttggatag tggtgaaatg aatttgtgta aataataagc
     2581 gcagagtaaa caagagggaa tttagaagtt agacaagtta gaatagcgtc tagattaatc
     2641 atgagcagct actaagggat ctagactttg acgcaaactc atggaataag gagtaggtct
     2701 tctcgtaatg gggaggacgc acaagaaatt gtgtcgtgtg ctgcagtaca tgtagatact
     2761 tgcgaggacg ttgattattg gatcaatcga gcatttaccg ctgtctacta gggtttctcg
     2821 tttcggacgc cataaacgag tcgaaatttt ttatgtattt ttaagtaaac gaaaaacgat
     2881 aaaatatgaa caagtcctga ataaagtgaa aaaattgata taaaacatag agaaaatgaa
     2941 atttacgtaa tggaggaatg acaaatgaaa aattatgatc cgaatatacg attgggcaca
     3001 catactatta aggtttcttt ccaacgttgg gattacaaag gatttgtgac gtttagaagg
     3061 ggcggaaatt gtaaaggatt agatgtttta gcattagacg aggatgattt atacgatcaa
     3121 acattgactg ataatccaat tggattcggc ttgctacctg aagatgatga aggtaatgaa
     3181 tggtttaaaa tgacgcttat gaatgataat ggagacgaat tatctgttga agatacttgg
     3241 tcatatttga gtgattatat tgtcagcttt gaaatcattg aatttgtagc ggataaagaa
     3301 gaataaaaac tggaggaata aattttacag ataaaggctt agaaggagtc acgacgatta
     3361 ataaaaaggt agtattacct taggcattga gtaagga
//
LOCUS       DADGHT010000161         3374 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.166, whole genome shotgun sequence.
ACCESSION   DADGHT010000161 DADGHT010000000
VERSION     DADGHT010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.166"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            254..580
                     /locus_tag="JX887_002730"
     CDS             254..580
                     /locus_tag="JX887_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258654.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(697..1041)
                     /locus_tag="JX887_002731"
     CDS             complement(697..1041)
                     /locus_tag="JX887_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258655.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(1117..2364)
                     /locus_tag="JX887_002732"
     CDS             complement(1117..2364)
                     /locus_tag="JX887_002732"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAX1258656.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            complement(2361..3167)
                     /gene="proB"
                     /locus_tag="JX887_002733"
     CDS             complement(2361..3167)
                     /gene="proB"
                     /locus_tag="JX887_002733"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAX1258657.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
BASE COUNT          987 a          665 c          670 g         1052 t
ORIGIN      
        1 ccgtttacca agaggttgtg agactgtcgt ttaactctga atcacaagga acaatttcaa
       61 aaaacagttt ctcatgtttg ttgaatattg tgacttatga ttgaggagtt ggcagaagaa
      121 caccatttat tcggaaaaag gggatgtgac acgatttttg tcacattccc tttttttctc
      181 aaaataatga aactggaaaa ttttcagtag gtaagctaaa attcatttaa gaaaaagaat
      241 ggggggataa tagatgctgg aagaatattt tcaggaagtc gggttgacac tcgttgaatt
      301 acccattgaa ttttcagatg atcggttgat ttatcgtggc tatatcaaag aattgccaat
      361 aatcaatgcg gaaggtgaaa ctagaaaagc gatgcagcaa aaaatagctg gtatgtatca
      421 ggtgtatcgg gaacagctac tggctgaatc agcggaagaa gaaaaagaaa aaacgatgaa
      481 cttgtccatg gatgagctgc ttcgttatta tgatggcgaa acatttgacg gattttcgct
      541 tcttaacgaa gaggaaacag atttaccagg cagctggtag gcgaacgccg tttatatgga
      601 aaaagaggct gtgacaaaat ctttgtcaca gcctctaaaa agtccggcag ttttttgccg
      661 atcttcaagg cactctactt atcgtacgga tattttttag cggaaagtcc gattcaagtg
      721 gtttttattc agctgatatt tataagataa gtgaaaaatc ccagcaatca gtagcgtaat
      781 cgtataagcg attgaatgat cgaaaaaaga atagtaattg attgtcgcta ataagcataa
      841 tgcaaccatg taactaatgt gcaagcgtgt aaccagccct ttttgcccga ttttgtcaaa
      901 atactgcgac catttttccc gttgactccc tatgcttcgt tttttgaatt gaaagaaaag
      961 ggataaaata ccgactccca gaaaagcagc gatattcaga gaaataaggt aaataaaaaa
     1021 aatcattaaa atttcaaaca tattgacacc tttctagttg gatagaacct ttacagaaaa
     1081 aaggcaaaag gcgggaataa tgtttcacac gaaacattat tcgcggattt gtccatcgcc
     1141 ataaatgata tattttgtgg aagttaattc atttaacccc attggaccac gggcatgcaa
     1201 cttttgagta gagataccaa tctctgcacc aaaaccaaat accgatccgt ctgtaaaacg
     1261 agtggaggca ttgacataga cagccgccgc gtccacttca tttaagaaac gttgactagc
     1321 cgcataacta tctgtcacga tcgtttctga atgtttagta ttatgccgat tgatatgtgc
     1381 aattgcttca tccaaagaat cgaccacttt gacagcaagg atataatcta gatattcagt
     1441 atcccaatct gtgtcttctg ctaaagcagc cgtctctaga tattctaacg cacgagcatc
     1501 cgcacgtaaa gagaccccgt gttctaccag ttctttttca atagctggca agaaaaaagg
     1561 tgcgatctca gaatggatca gcaatgtttc tgccgcgtta cagacagatg gacgggaagc
     1621 ttttgcattg acgatgatgt tcactgccat agataactgt gcttctttat cgatatatac
     1681 gtgattattt cctgtacctg tttcaatgat aggtaccgtt gcctgttctt tgactcgttg
     1741 gattaatttt gctccgcctc gaggaatcag cacatctaag tattctgtca atcgcatcaa
     1801 ctgtcctgca gtttcatgag aagtatcatc gacaaactgg atggcataag gagattcgcc
     1861 agcactgacc agtacttgct gcaataattg gactaataat tgattcgaga agaatgcttc
     1921 tttgccaccg cgaaggataa cggcattccc tgatttgaat gctagactag ctgcatctgt
     1981 cgtgacattt ggacgagatt cgtaaatgat gccggtcacg cctagtggca cgcgcttttt
     2041 gccgattctc aatccgtcgg tgttcgtcca catctcatct acttttccaa taggatcgtc
     2101 taacgaagca attttttcga tctctgtagc catggcattg attcgctcag gtgtcagctg
     2161 caagcggtct tgcatcgttt cactgatatt gttttcgact gctttttcta agtctttatg
     2221 atttgcttca atgatcgctt gttgattctt tttgatggtt tgtgccattt gaacaagtag
     2281 ctcatttttg cggtttgtag gcataagtgc tagttgttgc gcgctatctt ttgcctgttg
     2341 tcctaattgc atcaagtcag tcatttcaag tcctccttaa ataaagtacc tacttctttt
     2401 cctgcaagaa tatcaaaaat aattgccgga ttttttccat ttgctaaaat cattgcgctg
     2461 tttgcttcaa atatcctaga agcggctttt aatttactct gcataccgcc tgttccaaat
     2521 gtgctaccag caccacctgc ttgtgccaga atcttttcat cgattttatc gatatagcga
     2581 tacatctgag cctcgggatt tgtagtcgga ttatctgaat aaaacccgtc gatatcagaa
     2641 aggacgatca aaaggtctgc cgcgacaagt tttgccatga tggctgacag ctgatcatta
     2701 tcgccaaatt ttgtcagatg atctaattca tccactgcta cagtatcgtt ttcgttcacg
     2761 atagggatcg tgtccataat caaaagctgt tccaatgtat tcctcacatt tttacgactt
     2821 tcaggataat ctaccacgtc tcttgtcacg aggatctgtg ccgtctgttg attatataca
     2881 ctgaatcttt gattatagat attcatcagt tcggcttgac caacagccgc cgcagcttgc
     2941 tgttcaggaa tcaaagtcgg acgttctgac aaatgtaatt tatgcatacc aacgcctaca
     3001 gctcctgatg agactaagat cacttccttt ccccgatttc taagatcaga aaggacaaaa
     3061 gctaactgat cgattgccgc aagattgata tttccattgg gataaatcaa tgtacttgtt
     3121 cctactttga caataattcg ttttgcattt ttaatttctt tacgcatgtg acacctcaat
     3181 caaatatcca ctcattaatt tcgttctatt ctacttgttt tgacgagtaa agtcatgtaa
     3241 aaaatagttt ttttgtacaa cttgtagtcg tttggaaaaa gaacgaatta atggtttact
     3301 ttaagatagc agaatttctt gaagaatttg taaagaaagt cttttacagc ctcggatatg
     3361 ttagaatagg agta
//
LOCUS       DADGHT010000162         3350 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.167, whole genome shotgun sequence.
ACCESSION   DADGHT010000162 DADGHT010000000
VERSION     DADGHT010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.167"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            591..1760
                     /locus_tag="JX887_002734"
     CDS             591..1760
                     /locus_tag="JX887_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAX1258658.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            2233..2787
                     /locus_tag="JX887_002735"
     CDS             2233..2787
                     /locus_tag="JX887_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAX1258659.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            3041..>3350
                     /locus_tag="JX887_002736"
     CDS             3041..>3350
                     /locus_tag="JX887_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258660.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     L"
BASE COUNT         1295 a          413 c          543 g         1099 t
ORIGIN      
        1 atcttcctaa aataagcgaa tagcattcct aaaacctata aaatttttag atgaagcgac
       61 aagtggacaa ttaataaact acttgaacat gaaattatgg atcacctttc aaatttagaa
      121 aatggaattc ttatacttat tgcgcaacat ttattgattg caaaattatg tgacaaaaaa
      181 aactagtaga agaaagaata atggcttgat aataaagtac tacctattaa aggtagtact
      241 ttatttaatt tagtataaat taacatacta ctatatttta ggtttcatat tatataaatt
      301 aataatatac taccatttgt tggtagtata atttaaaggt aataagttat tcttttatta
      361 ctatgtttgg gttttatagc aaagaaagtt taataagagt ttggacctag caaacaatat
      421 taatgaggtc attaaatctt attatcttta gtgatataac gaaatatcta cacagacaaa
      481 atgatagcgt aaaatatttt gtgtaaatag atatttaggg tagaaaaaaa gaaagtccat
      541 tctgtaaaat taaagttacc acaaccgaaa ttttatagga ggactttctc atgcccaatt
      601 ttactacaga aattatggaa acactaatca ataaaggtga tttagatgaa ttatttcgat
      661 gtcatttaga attagctgtt aattcattat tgcaggctga attaacagct tttcttgatt
      721 atgaaaaata tgatcgtgct gggttcaatt caggtaattc ccgtaatggg aattattcac
      781 gttcattcag aacagagtat ggagaattaa atttggtaat tcctagagat agaaatggta
      841 agttttctca acaaacttta cctgcttata aaagaaccaa tgactcttta gaaaccacta
      901 ttattcagct atttcaaaaa ggaattacta tgtctgaaat ctctgaattg attgaaaaaa
      961 tgtacgggca tcactatacg ccacaaacca tttcaaatat gactaaaata gtttctgaag
     1021 atattattgc ctttaaagaa aggtccttag aatccagata ctctgtcatt tttatggatg
     1081 ctactcacat tcctttaaaa agacaaactg tttcaaaaga agcagtttat attgtaattg
     1141 gcattcgatt agatggaacc aaagaggttc ttgggtttag tcttgctcca actgaatctg
     1201 cttatgtttg gaaagagatt cttcaagacc taaaagaccg tggtttaaaa gaggttttat
     1261 tagtcgtaac tgatggttta agtggcatta acgatagtat tcatagtgtt tatccaaatg
     1321 ctcaatttca acaatgttgt gtccatatat ctagaaatat cgctcataag gttcgtgtta
     1381 gtgatcgaca agaaatctgt agcgatttca aattagttta tcaagcaagt tcaaaagaag
     1441 aagcaaataa tcaaataagg tttatgatag ataaatggaa aaagcagtat ccacgagtgg
     1501 ttaaattgct catgaatcct gctatattaa ccttttataa tttccctccg tcaatcagaa
     1561 gaactattta ttcaactaat ttgattgaag gttttaacaa acaattaaag aaatatacca
     1621 aaagaaaaga gcaatttcct aatgaagaat ctctggagag atttctagta tctcaattca
     1681 acaactataa tcaaaagttt ctatgccgag ttcataaagg ttttaaagaa atacatgata
     1741 cattagaatc aatgttttaa cttgatcaac agaatgggct tttccattta cacaaaatta
     1801 ttgacgctcc cgacaaaatt atgatcttgc gtaaagttat aaaatattaa taaaaatatt
     1861 ttattaatga aaagcttggt agcacggtta ttcatatgct aatttatttc actttatagt
     1921 aaggggagtt cttagtatat tgttcaaact taaatttcat ataatttaat tatgtaaatt
     1981 agctattcta agaacttcta cggataactg cccgtctaaa atttaaataa gagcttagaa
     2041 tcttcatata agtaaggtta atttttttgt acaaaaaagt cggaatattc tgagttactg
     2101 aaatgatata aaatcataaa ctaaacccct tgattttctt cacttttaac agagtatata
     2161 tataagttca tgattatggt aaaatatata tataatcatg aactcagaat atttttaaga
     2221 agggaaacaa tagtgagcta taatgtacaa ccgttaagga caaatgaaga gatacaagat
     2281 tttcagtttt ggctaagaag aacaagtaat ccagaaagag atagtttttt atttttgttt
     2341 ggaatcaata atgggttacg tatgtcagat attataggat taaaagttgg agacatacga
     2401 ggtaaaagta agcctattat tgttgaacat aaaacaggta agcgaaaacc gatttttata
     2461 gataatttga gagaagagat tttattatat actgaaggta aagaagaaaa tgattggtta
     2521 tttccaagtc ggcaacaagg tcgacatata acaagggatc gtgtctatca gatatatgca
     2581 gatatagcag aaaaattagg aagagatgat ataggaacac atacattaag aaaaactttt
     2641 gggtatcact actacaagaa aactagagac attgctacct taatgtttat ttttaatcat
     2701 agctcgcaag caattacaaa aaggtacatt ggtataactg aagatgaaat aggggcatcg
     2761 ttacgtggtt ttaaattggg aggctaattg agatattagg atatattttt tgtgtataat
     2821 gaaaacttag aaggtgagat taatgaagat aactgaattt tcggaagtat ttaaaacgtt
     2881 tagtaacatt tacaatagaa taccagagat agaacaaaat gttgtagttg ataatgatta
     2941 ttatatagag aatgatttta ataaaccaag aaaatatgac aacctataca attttataca
     3001 caatagaaca acaataaata acaacagtaa cactcgagtt ttgattaatt cagcatattt
     3061 tcatattaaa tatttaaaga aatatgagta tgaagaagtt gtattagatt atgggctaaa
     3121 tagacagtca tttttaattt atgcaataaa taacggaaat ttgccaagca ataaaaagaa
     3181 cataattatt gaaacatatg cctatctgga ggggggatct aaaaaactaa ttaagtcatg
     3241 taatatagag tatcaattat cagtaggaga aattaaatgt gttttcgaag aagatttaga
     3301 acttgactta aaaaaaattt ttgccagcat tcatgattat ataggtttga
//
LOCUS       DADGHT010000163         3310 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.168, whole genome shotgun sequence.
ACCESSION   DADGHT010000163 DADGHT010000000
VERSION     DADGHT010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.168"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(54..788)
                     /locus_tag="JX887_002737"
     CDS             complement(54..788)
                     /locus_tag="JX887_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAX1258661.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="JX887_002738"
     CDS             1115..1525
                     /locus_tag="JX887_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAX1258662.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="JX887_002739"
     CDS             1518..2219
                     /locus_tag="JX887_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAX1258663.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..>3310
                     /locus_tag="JX887_002740"
     CDS             2219..>3310
                     /locus_tag="JX887_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAX1258664.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYL"
BASE COUNT         1014 a          607 c          654 g         1035 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt
//
LOCUS       DADGHT010000164         3280 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.170, whole genome shotgun sequence.
ACCESSION   DADGHT010000164 DADGHT010000000
VERSION     DADGHT010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.170"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1843
                     /locus_tag="JX887_002741"
     CDS             <1..1843
                     /locus_tag="JX887_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HAX1258665.1"
                     /translation="YAQVLDQRPYKQAGNAEMTVNFISPYSDLAGQEAELALKSSRNL
                     LFVELPSDKEFKDDIAMYARMNLYLTTTYSSVVKNFDAIRSEKSGELQELSASINDQL
                     NELLKSAKFFYNGAEIQLTGSDFKAKFQSALQKMAEEVYHKLNQIDAPKEKEDILYLV
                     KESKNEIIEDPSNEQAVQEIFNFINDQKRNHLTITMKTIRDRFETKQPYGFTELDVEW
                     CIAKLFMSGKIDLLYNNVQISRMDDPNSIVMIIQKRRESEKIKIEPSAVISPKAKKLV
                     DEIGRELFQSRNIVDENNNEHTMENFKKYLKGQLDNLRSYFDLQNTYTYPSAYEYEQI
                     KKYLEVIVQTSDVEDFFYTIKKYRDELFDWAETYDKIKNFHKQNSTQKKIWENAQDKI
                     RLIEKSRRQTSSQEIDQLIHEMKTILKKADPYSDMMKLNELIQEFIEQYNQLLELESQ
                     EILNKLTEEKQATFKLLEGKDFKDQFVPIVDQEFQELKAKIEQANTIDDLVFLSLNVA
                     EQYLIFNQRFDNEENRRRQEEQARKQIEAANLIRETEKDEIDSAAKAEEIAIVKPTIQ
                     QKTVPMRTLNVHVKTIKSAADIDELTAEINQKLKEQLQENTEITIQF"
     gene            1907..>3280
                     /gene="pglX"
                     /locus_tag="JX887_002742"
     CDS             1907..>3280
                     /gene="pglX"
                     /locus_tag="JX887_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HAX1258666.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQA"
BASE COUNT         1298 a          447 c          604 g          931 t
ORIGIN      
        1 ttatgcacaa gtgttagatc aacgtccata caagcaagct ggaaatgctg aaatgacagt
       61 taattttatt tcaccatact ctgatttagc aggtcaagag gcagaacttg cgcttaagag
      121 ttcccgtaac ttattattcg tagaattgcc atcagataaa gaatttaaag atgatatagc
      181 aatgtatgct agaatgaatc tttatttaac aacgacttat tcgagtgtag taaagaactt
      241 tgacgcgatt cgttcggaaa aatctggtga attacaggaa ctaagtgcaa gtatcaacga
      301 tcaattaaat gaactgttga aatctgcaaa atttttctat aacggtgcag aaattcaact
      361 gacaggctcc gactttaaag caaaattcca atcagcactt cagaaaatgg ctgaagaagt
      421 ataccataaa ttaaaccaaa ttgatgcgcc taaagaaaaa gaagatatct tatatttagt
      481 gaaagaaagc aaaaatgaaa ttattgaaga tccatcaaat gagcaagcag ttcaggaaat
      541 tttcaatttt atcaatgatc aaaagagaaa tcacctaacg attacgatga aaacaattcg
      601 tgatcgtttt gaaacaaaac aaccgtatgg attcacagaa cttgatgtgg aatggtgcat
      661 cgctaaactt ttcatgtctg gtaaaattga tttactttat aacaatgtac aaatttcacg
      721 gatggatgat ccaaatagta ttgtaatgat tattcaaaaa cgacgagaaa gtgaaaagat
      781 aaaaattgaa ccaagcgcgg tgatttcgcc aaaagcaaaa aaattggttg acgaaatcgg
      841 tagagaactg tttcaaagtc gtaatattgt tgatgaaaat aacaatgaac atacaatgga
      901 aaatttcaag aaatatttaa aaggtcaatt agacaattta cgctcttatt ttgatttaca
      961 aaacacttat acctacccta gtgcttatga atatgagcaa ataaaaaaat atcttgaagt
     1021 aattgttcaa acgtcagatg ttgaagactt tttttataca atcaaaaaat atcgcgatga
     1081 attattcgac tgggctgaaa catatgataa aattaaaaat ttccacaagc aaaatagtac
     1141 tcagaaaaaa atctgggaga atgcacaaga taaaattaga ttaatcgaaa aaagtcggcg
     1201 tcaaacttct agccaagaaa ttgatcaatt gattcatgag atgaaaacca ttttgaaaaa
     1261 ggctgatcct tattcagata tgatgaaact aaatgagttg attcaagaat ttattgaaca
     1321 atataatcaa ctgttagagt tggaaagtca ggaaatatta aataaattaa cggaagaaaa
     1381 acaagcaaca tttaaattat tagaaggaaa agattttaag gatcaatttg taccaatagt
     1441 tgaccaagaa tttcaagaac tgaaagcaaa aattgaacaa gcgaatacta tagatgatct
     1501 tgttttctta tcattaaacg tagcagaaca gtatttgatc tttaatcaac gtttcgataa
     1561 tgaagaaaac cgcagacgtc aagaagaaca agcacgtaaa caaattgaag cagcaaactt
     1621 gattcgtgaa actgaaaaag atgaaataga ctctgcagca aaagctgaag aaatagcgat
     1681 agtaaaacct actattcaac agaaaacagt accaatgaga acacttaacg ttcatgttaa
     1741 aactattaag tcagcagcag atattgatga gttaacagct gaaattaatc aaaaactgaa
     1801 ggaacaactt caagaaaata cagaaatcac gattcaattc tagtgaaaag acaggcataa
     1861 aaaggtgcct gtcttttcaa aggttacata tagaagggaa agaaaaatgg ataagaaagc
     1921 gataaagaat ttcgcggtca atgcccgtag aaaattaatt gatgaagtaa tgactaaagc
     1981 aaaacgttta ggaattgatg aatcaaaaat tgaagatgtg aagaaaattg atagcaattt
     2041 acaagaaatc gaaaaatcag gaataagaat tcaaggaaaa gaaatagcgc aaagaaacaa
     2101 attgattgca gaactaaaac aacgtgcttc tgtcacttct tattcagaag cttttcaaga
     2161 gttaatcgaa gaggttgctt atacgtggtt taaccgattg attgccattc ggtttatgga
     2221 ggtaaatgat tatttacctg acacgtatcg tgtattatct agtgaaataa gtgggaaaat
     2281 tgagccagat attattacag atatttatga tgccgatatc tttgaagaat tatctagtaa
     2341 tgaacagcaa caagtcagaa cttggaaaac agataattca gcagaagcaa tggacaagct
     2401 gtatcaattg atttttataa aaatctgtaa tcaattgaat gattacttac ctgagctatt
     2461 tgaagaagta gaagattata cagaactttt gtttacagct tcttatatta aaaaagatgg
     2521 tgtaatcgct gatcttttaa gtattccaga ggatgatttc tatgttcaag ctggtggaca
     2581 ggtagagatt attgggtggt tgtatcagta ctataatagt gagccacata atcaagtggt
     2641 gaatatttat aaagggattg tcaaaaaaca agatattccg gcagcaactc aactatttac
     2701 cacagattgg gtcgttcgtt atatggttga caatagttta ggaaagtatt ggttagatca
     2761 ttatcccaat agtgaattaa gaaataagtt gaaatactta attccagata aatatgcttt
     2821 tgaacaagca acatctgtaa gtaatttaaa accagaagaa ctaaaaatta tcgataacgc
     2881 aatggggtct gggcatattt tagtttacgc cttcgatgta ttgatggaaa tttatcttac
     2941 gttaggatat tctgagcgtg atgctgcacg tgcaatcgtt gaatacaatt tatatggtct
     3001 tgaaatcgat aaaagagcgt atcaattgtc ttattttgca attatgatga aagggcgtca
     3061 atacgatcgt ctttttttga aaaaaagtct atcgccgaat ttaagagagt ttattgattc
     3121 tcctaaagtg acagacgagt atcaagagcg tattagtgaa ttgaacaatg ataagtatag
     3181 tgaacgctgg aatgaataca aagagttaat ttttgatcaa tttgaaaatg ggaaagaact
     3241 tggatcaatc attaagttag tcgataaaaa taatcaggca
//
LOCUS       DADGHT010000165         3275 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.171, whole genome shotgun sequence.
ACCESSION   DADGHT010000165 DADGHT010000000
VERSION     DADGHT010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.171"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            104..964
                     /locus_tag="JX887_002743"
     CDS             104..964
                     /locus_tag="JX887_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HAX1258667.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            976..1803
                     /gene="panB"
                     /locus_tag="JX887_002744"
     CDS             976..1803
                     /gene="panB"
                     /locus_tag="JX887_002744"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HAX1258668.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            1818..2666
                     /locus_tag="JX887_002745"
     CDS             1818..2666
                     /locus_tag="JX887_002745"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HAX1258669.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSVLVAIAVFIGKTRLIDN
                     FTFELQ"
     gene            2676..3071
                     /locus_tag="JX887_002746"
     CDS             2676..3071
                     /locus_tag="JX887_002746"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HAX1258670.1"
                     /translation="MKVTMLKGKIHRATVEQAELDYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
BASE COUNT         1274 a          337 c          657 g         1007 t
ORIGIN      
        1 aattaactat ggatgatatt tgaaaaaaac atactgtata tttgatttaa tttttatttt
       61 taagctcata tcgtaagaat gggacttgta gtctcacttc tttatggagg tgataattat
      121 gaacgttggt tttattggag ccggcaaggt aggttgttca ttcgggaagt atttccagga
      181 acataaaata caagtaacag gattttatag taaaagcgaa gactcgtcat tagcagcttc
      241 gaattttaca tctagtaaac aatatttaaa cttaagagaa ttagtagatg aaaatgatac
      301 tattttcatt acgactcctg atggtcaaat tcaggaggta tggcaagaaa ttaaaaatta
      361 tcaaatcaaa aacaaattaa tctgccattg cagtggtgca atatcttcag atatcttttc
      421 aaatatacag gactatggtg cttatggcta ttctgtccat cctatgtttt caatatcaga
      481 taaatataat tcatacaaaa aattaaaaaa atcttttata acaattgaag gcgatgaaaa
      541 atatgcaaag tttttatgtg atttcttcaa aaagttaggt aatagtactg taattgtatc
      601 taaggagaat aaatctcttt atcatgccgc atcagtagta tctagtaacc ttgtgctagg
      661 acttattaat acaagcgtta catatctaat tcaatgtgga tttactgaaa aaatggcaat
      721 tgaagcttta tatccattaa ttgaatttaa tattagaaat ataaaagaaa aaggaattat
      781 agaaagtttg acagggccag ttgaacgttg tgatatttca acaattaaag gtcactgtga
      841 agttttatca gatgaagaca gagctttata tatgctatta tcaaaaaatg tattagagat
      901 agctatgtta aaaaatatta atagagatta tagtgaatta gaaaagtatt taggagagag
      961 ttaggagaga aatagatgaa aaatacagca gttacattta aagaatctaa attaagaaat
     1021 gaaaaattaa caatgcttac agcttatgac tattcaacag caaaaataat tgatgaagct
     1081 gggataaatg gaatattagt aggagattct cttggtatgg tatgtctagg acatgaagat
     1141 acactttcag taacaatgga agacatgatt catcatacta gagcagttac aagaggagct
     1201 aagaacactt tagttgttgc agatatgcca tttatgtctt atcaaacttc agtatatgat
     1261 tcagtagtta atgcaggaag attaataaaa gaaggacgag ctcaggttgt taaattagaa
     1321 ggagggatag aagtatgcga taaaatagag gctatagtaa aggcttctat acctgttatg
     1381 gcgcatatag gtttaacacc tcaatctgtt aatgcatttg gaggatttaa ggtacaagga
     1441 aaggacaagg aagctgctaa agaattaata agagctgcta aagctgtaga aaaagcagga
     1501 gcattcgctg tagtgttaga atgtgttcca actaagcttg cagagttaat ttctaaagag
     1561 atatcaatac ctacaattgg tattggagca ggtgcagggt gtgatggaca aattcttgta
     1621 tatcaagata tgttggggat gtatagtgat tttaccccta aatttgtgaa gaaatatgct
     1681 aatttatcag aagagatgaa taaagcattt acaaaatata tagaggaagt aaaagatgga
     1741 gtttttccag gtccagaaca tgggtttaaa ataagtgatg atgttttaga aaaattatat
     1801 taaaagggtc aagaaatatg gttatattta aaacagtgaa tgatgttaga agtcaagtaa
     1861 aagagtggaa aaaacaaggc ttaaaggtag gattagttcc tactatggga tatttacatg
     1921 aaggtcatga aagtttaatt agaaaagcat caaaagaaaa tgataaagtt gttgtaagta
     1981 tctttgtaaa tccaactcag tttgggaaaa atgaagattt aggtagttat ccaagagact
     2041 tagaaagaga tatagaagta tgcacaagag gtagagcaac agcaatattt aatcctgaag
     2101 ttgaagagat gtattgtgac aatgcaagta cttttgttaa tataactgga ttaacagaag
     2161 gtttatgtgg agctagtagg ccaatacatt ttagaggggt ttgcactgtt gtaagtaaat
     2221 tatttaacat aataccagca gatagagctt attttggaga aaaggatgca caacagttag
     2281 ctgtaattaa aagaatggtt agggacctta atattgatat agacgttgta gggtgtccaa
     2341 ttataaggga agaggatgga ctagctaaaa gttctagaaa cacatactta agtttagagg
     2401 aaagatcttc agctactatt ttaaataaat ctttaacttt agctaaggaa gctttaaata
     2461 atggagagag agacagctta aaaataattg agataataag taaaaatata aatacttata
     2521 atttggcaaa gattgattat gtagaagttg ttgattcttt atcattacaa agagtaaatt
     2581 atattgaaaa atcagtttta gttgcaatag cagtatttat aggaaaaaca agattaatag
     2641 ataattttac atttgaatta caataggggg ctataatgaa agttacaatg ttaaaaggaa
     2701 aaatacatag agctacagtt gaacaagctg agttagatta tgtaggaagt attactgttg
     2761 atatgaattt attagaagca gcaggaatat atgaatatga aaaagtacaa atagttgatg
     2821 ttaataatgg aaatagattt gaaacttata caatagctgg agagagagga acagggatga
     2881 tttgcttgaa tggagctgca gctagatgtg tatcaactgg agataaaata attttaatgg
     2941 catattgtga attaaatgaa aatgaggtta aggatcatag acctaaggtt gtttttgtcg
     3001 atgataataa taaagttgaa agagtaacat catatgaaaa acatggaagg ttatcagata
     3061 taattcttta ggttttgtaa tgttatttat atatagctag actattattg aaatatttat
     3121 tgattactaa ttggatagat gtcaataaag tagacacaaa aagagaagat acagactgta
     3181 gacaaagtcc attttatgtg aatcggctac actagactag acagaaaaaa taaggtgtgt
     3241 agaataataa aaaacacact ggaggatttt tcatg
//
LOCUS       DADGHT010000166         3199 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.172, whole genome shotgun sequence.
ACCESSION   DADGHT010000166 DADGHT010000000
VERSION     DADGHT010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.172"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            301..585
                     /locus_tag="JX887_002747"
     CDS             301..585
                     /locus_tag="JX887_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258671.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="JX887_002748"
     CDS             588..1004
                     /locus_tag="JX887_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258672.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="JX887_002749"
     CDS             complement(1141..1860)
                     /locus_tag="JX887_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAX1258673.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2513..2608
                     /locus_tag="JX887_002750"
     CDS             2513..2608
                     /locus_tag="JX887_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAX1258674.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2910..3155)
                     /locus_tag="JX887_002751"
     CDS             complement(2910..3155)
                     /locus_tag="JX887_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258675.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1065 a          597 c          499 g         1038 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtaccc
     2041 ttctgtatcc gttgggagag taaggctcaa ctgcccccta aaaagggttc taaaaaatct
     2101 ttaaaaaata aataaaataa acgcgcgcgc gcgagcaaaa tttcccgcca aaaaatcacc
     2161 cactttttaa aataaacagg ttcgcgcatg atattaaact gccaatctag ctccctatgg
     2221 tcgctgtaag aaggagtgat cgctacgctc tcacatttta cttgcagcag tcgcctttag
     2281 gctccttcgc caaaaataat tcattaggga ctcctttgtg gcgtcctgag agctcgtcta
     2341 agccgttcta agacaagatt cgataaaaac tatgtccttc gttctaaagc gccttacagg
     2401 cggtcagggc aagccctaac aaccccaagg caataaaaaa cttaggctta tttttgcttt
     2461 tttattgtat aattgattgt cgcctatccg acagtcttgc gactggaagg aggtgtgttt
     2521 cgtgttcact aactttattt gctcccttct tgttgggctt ttaagcgctt tgttcagtta
     2581 ctggttgaat aaccgaaaca agaagtaaaa cttaattaag gcgactcagc ccacaaaaaa
     2641 agccccagag aatccgacct ctctggggct ttcgtgtgtt tcgtgttcac ttatttgcaa
     2701 tcaaattata acagaaataa atatttattt caaaaatatc ctacaaaagt ctaaaatccg
     2761 taattatttc ttatatgcaa catttacaaa taaagtcgct ctgagagctc gtatttttcg
     2821 atttaagacg ttttatttag tttttggtgt atttcattgg tccaagctaa aaaactctta
     2881 gaagcgattt tagagccatt taaacccact taattatatt ctccatgaaa ttcgctccat
     2941 gcgtcaaaag ctgcgtctga aattccgccg tcttcgttca ctagttgcat taatttttcc
     3001 aacgatcgtt ttctttcggg tgtcatattt ttatattcca acaatttttc gtctgttaaa
     3061 tcgaacttga ttgcttgaat tgcttgctct aatttttcta agttttgaaa atattcgtaa
     3121 ggaaattttt ccattttttc tttctccagt ctcacaattt ttctagaaat aaaatcactt
     3181 ctttgccgtc tatactctc
//
LOCUS       DADGHT010000167         3141 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.173, whole genome shotgun sequence.
ACCESSION   DADGHT010000167 DADGHT010000000
VERSION     DADGHT010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.173"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            361..1365
                     /locus_tag="JX887_002752"
     CDS             361..1365
                     /locus_tag="JX887_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAX1258676.1"
                     /translation="MLGDSLVVLAGLSGTGKSQLVTSYAKALQLSDTQIKFISVRPFW
                     EDDSDLLGYADTVNSVYRPGDSGLIDALLEASRHKENIYMVCFDEMNLARVEHYFSQF
                     LSVLEMEPNTRKIKLYNEDLENKLYNSSTYPSTIEVGQNILFVGTINTDESTHQFSDK
                     VLDRSNIISLELVPFHEISEVNDYIQSDQKKRNQLKYDDFKNFKNSNPTNGLTQKEKE
                     MFWKLHLAINSKDKNIGIGWRILKQIDEYLKNLPVQNDLSRKEAIDIQLVQRVLSKIR
                     GSDEQLSELVGKWNENDLKQVGEFEQIINEYPESSDFKYTKKILLQKARELNLHGFTL
                     "
     gene            1349..3139
                     /locus_tag="JX887_002753"
     CDS             1349..3139
                     /locus_tag="JX887_002753"
                     /inference="COORDINATES: protein motif:HMM:NF016309.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258677.1"
                     /translation="MDLPFSLKLNFGYKSEEQEYELLFFQDEASLLEYTPVKVKEFSN
                     LSFTFNSIDKHAKLYIPELDDYLIENQVKEENGDICYIPSDDNIIIYNRDQGKTVPLI
                     PGYYTLYVKIGETIFYSRFEIILKDLGTPEWEKMKIEIEKMVGGLARTFIPKKTSRRE
                     ITTSNYLMNDQLFQRILEFENNIPQAIVSLESLKKEAKYRIDKRYNWKPIGSKNLVDQ
                     KTISQLQIHPEKRGLLYTPSRIIKYDIIENQWIKFILSYFKNFSLLADRYLEKILQGI
                     IEEKKREDKFTSAYSQSVQNYNTNSYNRKIENLKNNQQKIKHFYAYILEFLDTPVMKN
                     ISSRRPINVPKSLVMNPKYNTIYKMYLKSRNNRNTLNFSNRYQYYWKSTDVLYEIWCF
                     IKIIRSLSLQGYTPISGWIFENDILSQELPFLHEDTTVVLSKNDIRINLVYNNSMEKE
                     YFSNTLDIPVKTSSKRNKPDIRLDIILQDKYYIGSLIFEVKYKKLDNILDNDKGRQRQ
                     QLMAYKQNTMSSILAFPEILTRSLQAVSAVFALYPSNEGRKKTAPKYYEKEGIFFHLL
                     NPSSDEKELSVKIQTSIEERISLFNQQSRN"
BASE COUNT         1263 a          431 c          457 g          990 t
ORIGIN      
        1 gataattttt acaaaaagtt tattgatgaa ggtagtaaaa actatgtagg ttacgatgat
       61 tttataaatc aaacaaaaga tataattttt gtgccctatc tattacttca aaaaattata
      121 gaaactaaaa aagatattaa cgaaggcata gaaaatatct ctgattccaa aatatctcca
      181 gtaagttcaa ttattactga acaaacgcaa atagatatat ctgagttaga agataaacac
      241 gctattcaac aaaatgatca cttctctgaa cataatgaat ttatagaaag atttaatcag
      301 ctcacaattc gtagtaaatt acattactca aaacgagact tatggaattt tcatactgct
      361 atgttgggtg atagtttggt ggtattagct ggactaagtg gtaccggtaa atcacaatta
      421 gtaacatcct atgcaaaagc acttcaatta tcagatacac aaataaagtt tatttctgtg
      481 agaccctttt gggaggatga ttctgattta ttgggctatg ctgatactgt aaattctgtc
      541 tatcgtccag gagatagcgg tctaattgat gcactattag aagcatcaag acataaagaa
      601 aatatttata tggtttgttt tgatgagatg aatttagctc gggttgaaca ttatttctcc
      661 caatttcttt cagttttaga aatggagcca aatactagga aaatcaaact gtataacgaa
      721 gatctagaaa ataaattata taactcttca acctatcctt ctacaattga agtaggacaa
      781 aacatattat ttgtaggaac aataaataca gatgaatcta ctcatcaatt ctcagataaa
      841 gttttggata gatcaaacat tatttcactt gagttagtac cattccatga aattagtgaa
      901 gtaaatgact atattcaatc agatcaaaag aaacgtaatc aacttaaata tgatgatttc
      961 aaaaatttta aaaactctaa ccctactaat ggtttgaccc agaaagaaaa agaaatgttt
     1021 tggaaactcc atttagcaat taattctaaa gacaaaaata tcggtatcgg ttggagaata
     1081 ttaaaacaaa ttgatgaata tttaaaaaat cttccagtgc aaaatgactt atcaagaaaa
     1141 gaagctattg atattcagct tgtacagaga gtattaagta aaatcagagg ttctgatgaa
     1201 caattatcag aattagttgg taaatggaat gagaatgatt taaaacaagt gggtgaattt
     1261 gaacaaataa ttaatgaata tcctgagtct tcagatttta aatatactaa aaaaattctt
     1321 ttgcaaaaag ctagggagtt gaatttacat ggatttaccc tttagtctga aattaaactt
     1381 tggttataaa agtgaagaac aagaatatga acttttattt tttcaagatg aggcatcgtt
     1441 attagagtat acaccggtta aggtaaaaga attttctaat ctaagcttta catttaacag
     1501 tatagacaaa cacgcaaaac tatatatacc agaattagat gattatttga ttgaaaatca
     1561 agtaaaagag gaaaatggag atatttgcta tattccaagt gatgataata taatcattta
     1621 taatagggat caaggtaaaa cagtacctct tattccaggt tattacactc tttacgttaa
     1681 aataggtgaa actatctttt attctcgatt tgaaataata cttaaagatt taggtacacc
     1741 agaatgggaa aaaatgaaaa tcgaaattga aaaaatggtt ggcggtcttg ctagaacttt
     1801 tattcctaaa aaaacttctc gtcgtgaaat tactacttca aattatctaa tgaacgatca
     1861 actttttcaa cgaatattag agtttgagaa caatatacct caagcaatag tttctcttga
     1921 aagtttaaaa aaagaagcaa aatatagaat tgacaaacga tataactgga aaccaattgg
     1981 aagcaaaaat ttagtggatc aaaaaactat ttcacagttg caaatccatc cagaaaaacg
     2041 tgggctacta tatacaccta gccgcataat aaaatatgat attattgaaa atcaatggat
     2101 caaatttatc ttatcttatt ttaaaaattt ttcacttcta gctgatagat atttagagaa
     2161 aatcctacaa ggtattattg aagagaaaaa aagagaagat aagtttacta gcgcgtattc
     2221 tcaaagtgta caaaactaca atacaaatag ctataataga aagattgaaa atttgaaaaa
     2281 caatcagcaa aagataaaac atttttatgc ttatatcctt gaatttttag acacaccagt
     2341 aatgaaaaac atttcatcaa gaagacctat aaatgttcca aaatcacttg ttatgaaccc
     2401 taaatataac actatatata aaatgtattt aaaaagtaga aacaatcgta atactttaaa
     2461 tttttcaaat agatatcagt attattggaa aagtacagat gtactctatg aaatttggtg
     2521 ctttataaaa attattagat ctctatccct gcaaggctac actccaattt ctggatggat
     2581 ttttgagaat gatattcttt cacaagaatt gccgttttta catgaagaca ctaccgtagt
     2641 attgagtaaa aatgatatac gtattaatct tgtatataat aattccatgg aaaaagaata
     2701 tttctccaat acactagata tcccagtaaa aacctcttca aaacgaaata aacctgatat
     2761 tagattagac attatccttc aagataaata ctatatcgga agcttaatat ttgaagtaaa
     2821 atataaaaaa ctagacaata tacttgataa tgataaaggt aggcaacgtc aacaattaat
     2881 ggcttataaa caaaatacta tgtcaagtat tctagcattt cctgaaattc ttacacgttc
     2941 tttgcaagct gtctctgctg tctttgcttt atatccttcc aatgaaggaa gaaaaaaaac
     3001 tgcacctaaa tattatgaaa aagaaggtat tttttttcac ttattaaatc cttcatcaga
     3061 tgaaaaagag ctttcagtaa aaattcaaac aagtattgaa gaaagaattt cattatttaa
     3121 tcaacaaagt agaaattaaa a
//
LOCUS       DADGHT010000168         3094 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.174, whole genome shotgun sequence.
ACCESSION   DADGHT010000168 DADGHT010000000
VERSION     DADGHT010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3094
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.174"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1789)
                     /gene="brxC"
                     /locus_tag="JX887_002754"
     CDS             complement(<1..1789)
                     /gene="brxC"
                     /locus_tag="JX887_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HAX1258678.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLG"
     gene            complement(1814..2389)
                     /locus_tag="JX887_002755"
     CDS             complement(1814..2389)
                     /locus_tag="JX887_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HAX1258679.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(2389..2988)
                     /locus_tag="JX887_002756"
     CDS             complement(2389..2988)
                     /locus_tag="JX887_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HAX1258680.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT          944 a          605 c          406 g         1139 t
ORIGIN      
        1 tgcctaattt ttcataggca aaactatttc ggtctagaac gccgtcaaaa attcgtttag
       61 atagttctac gatcaaatca ctatctgtaa tattttgatt tttaatctca cgagtaattt
      121 cctgttcttc atcagtttgg aaaatataac tatctaagtt cttccgcaca aagttttcct
      181 taattaaaag gtccaatgct tcttctactc gttttttagt ttccaggcgg tcttcgttga
      241 tatttcttat catcaagctc gtaatatttt caacatttgg tttgatggct tgatcaacat
      301 atttaatcat gaataaaatt cgtaagacat ttacgttaaa gttatctata tcagttggtc
      361 tttgaatatg agaattattt gtagcttgtg taatcactcg gctaattgct gtatcaatcc
      421 aacgttctaa cgagtaataa aactgatcta aagaaaccaa actggttgta tcattttcct
      481 tatttcgttc agcggcttct ttaaacattg ctagtaatga acgttcacca gacgataagt
      541 ttgatccttg atagctgtga ttacgaatct cggttagaat ttgccccaat aaattgaatt
      601 gatagggaat aaatggataa acttctgcgt aattttcagc atcttggaag agctttaatt
      661 caggactatc aacaaagagt aatttatttt tcaattctgt ttgaacagtt tcaaattgta
      721 aggctaaaga atcattggca aactcttttt tcttcaaaat acgttcttta attacttcat
      781 cggcatttgc tgaagataaa ctcacagttg tggcaaaacg atccttgatc ttagaaaaat
      841 cattatcaga attgttatca aagtttgtta cgtgatcaat cgcttcctga cttgtcacta
      901 atacccaagc cttaccttca caaattcgac ccaaatcttc cacaacggtt tgtaactgca
      961 aagtcaactc acgattaccg ccgatatatt gtccgacctc atcgactaga aaggcaatat
     1021 gatggtctgc ttctttggaa tcaagatagc ttttaactag atttgcaaag tcatcaatgc
     1081 ttattaaata atttcctgat gctttttcta aaaaattatc aatagcggct tcactcataa
     1141 aatcgatttt aagtgccgct tctttgatat catcttggat ccaatcaaac tcatggcgct
     1201 cttcttgcca ttttgcccca ttaatctctt caaaagcagc tttgaatgca tcaaactttt
     1261 cttctttaat taaccgacgt tcaaaatctg ctagatgtgg aatcgtgctt aatccttgca
     1321 tttcgttaaa tacctttaaa aaaacattca cgattccgtt tttgtctttt ttaccacctg
     1381 catcactttt tgaatcaata ttaaacagaa taacatctgt atttatttgt gagcaccgtt
     1441 ccatcgttgc caaagtcagt ggatctttga ttttcccatc ttctttgaag taatcaatgg
     1501 ctttcttgtc atttatttct cgatttgcga gcaagtaaga aataattttt aagaaatgag
     1561 atttacctga accaaagaac ccctgaatcc aaacacccat tttatctgtt ggtgtattga
     1621 tactccgttg gtaggcatca aaaattgttt taaagtgttt ttgtagttct ttcgtaacca
     1681 cgtattcttc taattcttgt tgaacatttt catcctttgc ttgaccgacc ttaataactc
     1741 cttgaatatt tcggtcaatt ggttttgcaa aaatatcttt aattagcatt taatctccta
     1801 ccttccatcc caactaaatt ctaaatgctc gataataatt atcatcttta ttggtattaa
     1861 gaattgtcaa acttaattca tcatattccc ctggatacat catcacaact ggtacgcgat
     1921 caaatacctg atgcatttta tttaaaatag agtgcgctct aattaatgga tataattcgc
     1981 caattcctgt caggaacaca actgattttt ctggtgtatg ggcatccaca tattcaaaaa
     2041 atacattttc ttcctcaggt aaatccattt tcaataaacg accaatgctt tccactaatt
     2101 tttgtaaacc acgtcgttct tccatcttaa tcgctttttc agtgaaaccg cgtttttcta
     2161 gatactctaa cataatcaca tagagattat aaactttcac ttcataatta tcaccaacag
     2221 atgttccaga tatatcatta atataatctc ttacaattaa ctcgtctttc ggatcgtagt
     2281 caaagatata atagcctact tcattaccta aaccacgatt caataaaaaa tcttcttttt
     2341 gaattacttc attcaacttt tccaaatgct cttgaatcga taatgacatt ataaaattcc
     2401 tcccagtgct agtacaatat ctttacgatt cttgtcaact aaccattgaa tcaatcgttt
     2461 atctaataat atcggagtca ttcgtccata ttctttttcc cctctgacta atcctgtttc
     2521 aattagattc gtttgataag cggcaataag ccgtttaatc gtataatctt tccattttga
     2581 aatatcttct gaacttctcc gcttctctgt aaaaaaagaa cggtaatcaa ctggtgttaa
     2641 ttgcaaattt cctttacgta gattttcagc atatacctca gtcataaatt cattaaaaag
     2701 atcatcaatc ataaggatgg aaatcaaatt cactaacttt tgattatcta tatttaactg
     2761 attgaaaagt tgcaatccag cttcatccag ttgactaact ctccttttca cgttctgata
     2821 gatttctttt tgacggttac tgctcactgc aaaaaaaata ttttcatgtt catttttctc
     2881 tttaatttct atatctgtat atccttctag tcgtaattga atatataact tgaactctga
     2941 aaaccaaaag cgtttagaaa ctagaccagc agaatatttt ttattcaata gattgcctcc
     3001 taatcatcta taattcaata agtaaacaag tgttttttgc tcatcgttag cattcatttt
     3061 ttagtatcta ctatacaata catatttatt atag
//
LOCUS       DADGHT010000169         3038 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.175, whole genome shotgun sequence.
ACCESSION   DADGHT010000169 DADGHT010000000
VERSION     DADGHT010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3038
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.175"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(26..961)
                     /gene="murB"
                     /locus_tag="JX887_002757"
     CDS             complement(26..961)
                     /gene="murB"
                     /locus_tag="JX887_002757"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAX1258681.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1034..1954)
                     /locus_tag="JX887_002758"
     CDS             complement(1034..1954)
                     /locus_tag="JX887_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1258682.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2067..2819
                     /gene="xth"
                     /locus_tag="JX887_002759"
     CDS             2067..2819
                     /gene="xth"
                     /locus_tag="JX887_002759"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAX1258683.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
BASE COUNT          856 a          612 c          526 g         1044 t
ORIGIN      
        1 tacttatttt aagttccatt acttattaat tggctaaact tctgcttgtt tctgatattg
       61 cttgtttttc tccaatgatc cgcacttctg tttctaaaga cacatcaaat ttttctttga
      121 ttacttcttg gatgtgcgca atcaattcaa tataatctgt cgctgtcgca tgatcgatat
      181 tgacgatgaa tccagcatgt ttttcagaga cttgtgcacc gccccatttc aggccttgca
      241 atcctgcttg ttggatcagc tgacctgtat agtgtcctac tgggcgctta aagacacttc
      301 cgcatgaagg gtattctaat ggctgttttg attgacgcaa ttcggtcaac tcatccattc
      361 ttgctttgat tgcttcataa tcccctgttt gcaaactgaa tcgagcttcc aatacgatag
      421 cacgtaattc ttggacttta ctgtgacgat aagaaaatac catttcgtct tttgtcaaag
      481 ttttcaatgt tccatcttca agcaaaagat ccacttcagc aaaaacatct ttgatctctc
      541 cgccatacgc acctgcattc atataaaccg ctccaccgac acttcccggg atgccgcaag
      601 caaattcaaa tccagtcaat gattctgcca aagctgcata agtcgtatca atcagtgagg
      661 cacctgcttc cgcaatgacc atcgttcctt tgacatgaat ctgtttcatt tcagtcagca
      721 tgatgactac accgcgaatc ccgccatctt gaacgatcag attgcttgca tttcctaata
      781 ccatccaagg tatatcatgg attcggcaat aatcgatgat ttgctttact tcttcttgtt
      841 ttttcgggaa tgcaaggaca tcagctggtc cacctgtttt cgtaaacgta tagttcatca
      901 atggttcatc aaacaatata gtaatcgtgg ctaagctttc aactatttct tctttattca
      961 ctgaggattt tcctttcttt tctcaaacgt cctcattatt ctatcacgct taatacaatc
     1021 ttgccagtct tgttcaaagt tgatgacggt agtgatcttt aagcacttcc tcacataatt
     1081 catgacttct tacaacttct ttttgtttaa gcaattctgt ttccgattta cctaaacgga
     1141 tctgagaaaa gaaggcctct accattggct caaacccgcg tttgactagc gtgtttgtcc
     1201 agtcgccaaa ttctttcact ttttttccat cagcatcttg aatgacaagc tgggtcagat
     1261 cgtttacttc ataagtacca tttttacttg ttacttgata tttttctata ttagcgccac
     1321 ttgctaaatc catcgttaaa atagccgttt gattttgtgt ttctaattgt aaaatggcat
     1381 attccaaaaa ttcctttgtt tctcttatct ggtattttgt tctcaaaatg ggttcatcta
     1441 ataaatacac agctgtatca ataagatgta aaaacaaatc ataaaggacg aactctgtcg
     1501 tttcttttgc cgctattcga tttttttgca ggtggatcaa ccgcttatct gggatacgtt
     1561 tcaattcttc taccatagga gcaaagcgcc ggttgaaacc gatcatcaaa attatttggt
     1621 tcttatcagc taattcttgc aattcacgaa cttcatttag atggacactc agtggtttgt
     1681 caatataaac atggatacca ttttctagac attttttggc taattcataa tgtacttttg
     1741 ttgctgcgtg gatcatacat gcttcgattt tttcttctaa aagctcatcg atcgtttcat
     1801 atagatgttg gaacccgtac tctttttgaa ttctttcttt tgtttcttta tttcttgttg
     1861 caaaataaaa atcaagtgtt ccttgttttt tcgcataagt tggtaaatat gctttttctg
     1921 cgatattccc tacaccgatt acaccaatct tcatctactt tcctcctgga tcatttagtt
     1981 actttcatct tacaccattt tttactaaaa tgaggtacaa tagtatcgca aaggtaagga
     2041 aattaattcg aaggagtgtg cttttattga aatttatctc ttggaacgta aacgggcttc
     2101 gtgccatcgt aaataaaaat tttttagaag tttttcatga gttagacgcc gattttttct
     2161 gtctgcagga aacgaaactc caagcaggac aaattgattt agatcttcca ggttattatc
     2221 aatattggaa ttacgcggaa cgaaaaggct attccggcac agcgattttt gctaaaaaac
     2281 cagcattgaa tgccacttac ggaatgggta tcgatatcca tgatacagaa ggccgtctga
     2341 ttactttgga atattccgat ttctttcttg taacctgtta cacgccaaat tctcaaagcg
     2401 aattaaaacg tttagattac cgattagaat gggaagaagc cttttataat tatttggaaa
     2461 atctaaaaaa acaaaaacca gtcatcgtgt gtggggatct aaatgtcgct catcaaaaga
     2521 ttgatttgaa aaactggaaa acgaatcaaa aaaatgctgg attcactcca gaagaaagag
     2581 cggctctttc tcgactgttg gataacgggt ttatcgatac attccgttat ttttatccaa
     2641 cccaggaagg tgtctactct tggtggaact accgattcaa ttcaaggaaa aacaatgctg
     2701 gttggcggat cgattacttt ttgacgagca aagatttaga gccaggacta gctgatgcaa
     2761 agatccatac ggacattatg ggcagtgatc attgtccagt agaattagat ttgaaataaa
     2821 gaggttgtga aaaagtcgtt tagtttcgag tattaagaaa aattttgtga aaatggcttt
     2881 ccacattttg cataaatttg gcataatacc gagaaactgg cttttgaaca ctgtttatcg
     2941 agagattgtg aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagttc
     3001 ctcatatttt tcgtttggtt gggcttatta ccgcagat
//
LOCUS       DADGHT010000170         2992 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.176, whole genome shotgun sequence.
ACCESSION   DADGHT010000170 DADGHT010000000
VERSION     DADGHT010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.176"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(106..1053)
                     /locus_tag="JX887_002760"
     CDS             complement(106..1053)
                     /locus_tag="JX887_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1258684.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            1299..1763
                     /locus_tag="JX887_002761"
     CDS             1299..1763
                     /locus_tag="JX887_002761"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAX1258685.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(1825..2868)
                     /locus_tag="JX887_002762"
     CDS             complement(1825..2868)
                     /locus_tag="JX887_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAX1258686.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
BASE COUNT          990 a          593 c          571 g          838 t
ORIGIN      
        1 agaagctact tctggaacac catttattcg gaaaaaagga ctgtgacaag acttttgtca
       61 cagtcctttt tcatttaaaa aaatgtttac ttcatttgac gtatattatt ggtgaggctt
      121 caattcattt ggcttcactt tttctgtttc tcttatgata taaacaggac gctgtttcgt
      181 ttctaagaag attttcccaa tatatttccc gatgattcca agacataaca attggattcc
      241 accaatgaac aggaagatcg agaccatgga aggccatcct gatgtaggat caccaaacaa
      301 caatgcccgc aaaataatga acaaaattgc aataccagaa ccgacacaag acaaagcgcc
      361 gataaatgaa gcaatcgtta acggtgcatc cgagaagttc acgataccat caatcgagta
      421 gttgaataat ttccagaagg accaagatgt ttcgccagcc acacgttcgc ggttttcata
      481 agaaatatat tctgttttaa atccgaccca gctaaataat ccttttgaaa atcggttgta
      541 ttctgttaat tctaggacgg catccaccat ttgacgagtc atcaagcgga aatcacgagc
      601 gccatcgacc atttctgtat cgctgatttt attgatcaac tggtagaatt ttttcgcaaa
      661 gaaactgcgt atcgcaggct cgccttcacg agtcgaacgc cgggtgccga cacaatcgat
      721 atcagaagta gtgatccggt tgatcatctc aggaagcagt tcgggcggat cttgcagatc
      781 aacatccatc acggtcacta aatctcctgt agaagcttgc aatccagcgt acagagccgc
      841 ttctttccca aaatttctgg aaaatgagac aaagcggaca taaggataag ctgaggctag
      901 cttcttgatt gctgctaacg taccgtcttt tgatccgtcg tcaataaaca aatattcgaa
      961 ctcatgggca cctttgaatt tttcaacctc atcaaaaaaa agaggaacag ttttttcttc
     1021 attaaaacat gggacaacaa ttgatacttt catcgtttct atcctttcaa tcgtatgttt
     1081 atatatggtt tacattcaaa atttaataaa ccttaaataa cacctttaaa atttgatttt
     1141 acgtaaaaga acaggtattc tttttgtaaa ctaacgtatt tagtttacca tgtttcctcg
     1201 gtttatcaaa cttttaagaa caatttttat tagttggcaa gtagttttgg atagagaaaa
     1261 aggaggaagt tccagtctat tgactaggag caaacaaaat gaaaatacac acacctatcg
     1321 gctttttatg gttagatgca gatgaatccg gattgactgc tgtatctttt cagccaattt
     1381 cagaaagcga atcagcgaat cagcgaattt taacgcgcac acaagaacag tttgaagaat
     1441 attttgcggg aaaaagaaaa gaatttgatg ttcctttatc tataaagaga ggtacgcctt
     1501 ttcagcaaaa tgtctggaaa gctttgtcga ccattcctta tggagaaatc cgaacgtata
     1561 aagaagtagc cgttgctgtt gatagtccga aagctgtgcg agcgattggg caggcaaatc
     1621 gaaccaatcc attgccaatc gttattcctt gtcatcgagt gatcgggcaa aatggaaaac
     1681 tgacaggata tatgggaaac gcaatagatg gggttgaaat caaacgccaa ttgttgttgt
     1741 tagaaggata tctgcaaaat taaaaacagt tgtgattcgg acattgttcc atgcgagaat
     1801 cacaactgtt ttttcatgtt cattctaaac tttgatcagc caaataaata gtaaagccat
     1861 cactgtttgg agaagcccga cagctaatcc ataagataag aagcgtgtac cttctttcat
     1921 gaattttgca aagtctaaac gcagaccaat tgccgctaaa gcagtgatct caaaccagct
     1981 gctgataaaa tgtgccgatt ggtcaataac tacaggtaaa gaaaacaagc tgttgaccaa
     2041 acaaaagatc acaaacccta atacatacca aggaagcggt aattttcgtt ttttctgcgt
     2101 atcagttggc gtttcaaaca gagctggttg tttcttgtgc atgaattttt caaacagata
     2161 gacaacaaca acgagcatca taatacgtag aatcttaaat agcatggcga attcgacaac
     2221 agaattgtca agtaagcttg ccccagcgac tacttgacca acagattgga gtgtaccacc
     2281 caaaagtgca cttttttcaa tgagatttcc accaaacaac tgtaatccaa gaaaagggag
     2341 agtcaacatc atcacagtac ccagtagatt gactagtgtg atgatctgtc ctttttcttc
     2401 ctctttcgca tggatggaag gggcgattga agcaatagca gaagaaccac aaacagcgtt
     2461 tcctccagcc atcatcaaag aagaagtatc gctgaattgc agttttttac caatcaagta
     2521 agcaccgatg atagtgactg acatttgcag taacacaaaa acaattcctt ttacaccaat
     2581 ttgagcaatc gtttgagctg tgacagttgc acctagtaaa aaaacagaga attctaatag
     2641 tttgctttca gcaaattttg tgccgattgc tagaacaggc tgtttaaaaa aagtatttcc
     2701 taataaaata cccaataaaa tagcaatagt cgctccacct aactgtggca gataaatagc
     2761 aagaagcctg ctgaaggcag cgatggcaaa agaaagcagt aaaccgggta agatttcgcg
     2821 gaccgctgaa tcctttacag attttattgg atgtgacaat gatttcattt gatcggttcc
     2881 tttcgtcaat aaatactaaa agcatactcg aacatagtag cactaaacca gtattttgac
     2941 aaaagaacaa gaggtcgtga caaaagtctt gtacgacctc ttgtttcgaa ta
//
LOCUS       DADGHT010000171         2956 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.177, whole genome shotgun sequence.
ACCESSION   DADGHT010000171 DADGHT010000000
VERSION     DADGHT010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.177"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            90..407
                     /locus_tag="JX887_002763"
     CDS             90..407
                     /locus_tag="JX887_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAX1258687.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(498..863)
                     /locus_tag="JX887_002764"
     CDS             complement(498..863)
                     /locus_tag="JX887_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258688.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1071..1553
                     /locus_tag="JX887_002765"
     CDS             1071..1553
                     /locus_tag="JX887_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258689.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1750..2640
                     /gene="pstS"
                     /locus_tag="JX887_002766"
     CDS             1750..2640
                     /gene="pstS"
                     /locus_tag="JX887_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAX1258690.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1010 a          460 c          566 g          920 t
ORIGIN      
        1 tttttaaaac atcacaagga aaaacttaac tatggtatta tctaaacata attttttcgg
       61 tatttaatat ttaattagga ggtaatattt tgctttttta tagtaatttt atcttaatag
      121 tagcgatatt attacttctg aatatatgga tttttgatag gagtagaaat tcaagtatag
      181 gttttagaac taaacgaagt ttgtcttcta aaaaaaattg ggtatactca caaactattt
      241 tttatggagg aattgtttta attagtttac tttcttcaac actttattct ttgaatatta
      301 tagatgtttc cacctcaaat tcaatatcta ttattggaat cattattgct gcaattatta
      361 cacaactgtt tttagtgttt ggagagaaga aaagaagtaa aaaatagaaa aactagtgat
      421 agttttggtg atataagaaa aacatatatg tataaaaaga agaaagtagc ttctctttgt
      481 acatatatgg tttgttttta tggatgccga gcttttttat aagataaggc taccgcccat
      541 aacgacccaa ggatttgtgg aactaagtaa atacctgcaa gaagcaagat cagctgggtc
      601 ggttttaaag gatgatagaa gtaacgccat tcagtaaaat tggcgcaaaa taaataggaa
      661 gtgacagtag atataatatt ggcaatgaat aaagatataa tacgcctgtt cctttgaaaa
      721 taatatccag caaaaagaga taaaaatatc aatgtgatga acccgcttac ggaatgataa
      781 cgaaaatcaa gcagtaaggc gaaatgcaca taaggaacaa aagataaaag caacggaagg
      841 tttttccagc aagtttttat catctttcat caccacctaa caagtgttat tattttgtta
      901 gttttattgt aaattgaatc ctgcaataat caattacttt ttcattattt ctagattaaa
      961 tgaataaact ctcatgccat tatctctaaa aaaaaagttt ttccccctaa tttttttaga
     1021 tagaaaattg tatagtatga tgagagaaaa agtagtttgg gggaacgtta atgagaagaa
     1081 aagcagtaat cgatcggctt tatttatttt tttggttttt tcctatcgtt ttgctacctt
     1141 ttacatgggt aaatgctgtt gtacaaggtg cggagatatt aggcctgatc caaggaagcg
     1201 gatttgtggt ttctaggaat tttccagctt tgattgtttt ctatttagtg ataagtgtag
     1261 gtctcttatt accaaaatct ctgatcaatc actacaattg gcagctgctt tacttttctt
     1321 gcttattagt atttacatct acgttttctt tgctgcctcg cttgattatc ggccctaatg
     1381 gtttgagcga gagtggattg aaggatttag cttattcctc catgtatttc ttgacgatca
     1441 aaccatggtt ctatttagta attgcctcat ttattcttgc aacatttttt tacttctgga
     1501 cagaaatcag gataaaaagt gaacgatctg tatctataaa aaataactat tgatggtgga
     1561 tcatcagtaa aaaaacatat gagctgcgta aaatgcatgt ttctcatatg ctttttttat
     1621 tattatgtaa agaatgcgaa aaacgtttac atgattttta cataacttaa ctatattttt
     1681 acagcaacca tacgagggat ttacagtcga ctgataaact ttagttgtaa ataagaaagg
     1741 agcaataaaa tgaaaaaagt attgtttact ctaggtatga tgggaattct tttagccgga
     1801 tgcggctcag gatcaggaaa tacagatggc tctgccacac aaaataattc aagtgactca
     1861 aatgaacaag taaaaatcgt tgcggtaggt tcgacagcat tacagccgtt agtcgatgca
     1921 gcacaagaaa gctttgtaca agaaaatcca aattatcaaa tctctgtaca aggaggagga
     1981 agcggaactg gtttgagcca agtcgaagct ggagcagtta ctatcggaaa ctctgatgta
     2041 tttgcagaag aaagagacgg agttgatgct tcaaaattag tggatcataa agtagcagtg
     2101 gtcgggatgg caccaatcgt caataaagat acagatgtca aagatatcac caaacaggaa
     2161 ttgattgata tctttacagg aaaaatcact aactggaagg aagttggcgg gaaagatcaa
     2221 aaaatcaacg tcgtgaaccg tgcaaacggc agcggtaccc gcgcgacatt cgaaaaatgg
     2281 ggactggatg gtgctacccc tgtgcagtcc caagaacaag attcatcagg aacagttcgg
     2341 cagctggtaa gtcaaacacc aggagcaatc agctatttag ctttctcata tctcgatgat
     2401 tccacacaag cactaagtat cgacggtgta gaaccaaaag aagagaatgt agcagataac
     2461 agctggggaa tctggtcata tgaacatatg tacacgaacg gaaaaccttc ccctgaagtc
     2521 caaaaattct tagactacat gatgacagaa gaaatccaag aaggacctgt caaagaattg
     2581 ggctatttac caatcacaat gatggaagta gaacgtgatc acgaaggaaa tatcaaataa
     2641 ctagcagata aacatgccac ggtagtcgtt actattaagg aaaaatcaac tatgtttccc
     2701 cacatataca tttttccttt aattgtgaaa aatagttcct catattttgc cgttttttga
     2761 gctaataccg agggtcagct gattgaacac cgtttattcg aaaaaaagag ctacgacata
     2821 gaactgtcgt aacttttttt ggctcttcgt caaatcgtgt tggtgaagac aaatttgaat
     2881 aaaacttaga ccgatatgcg gcgcgttctg tgcgccgcat atttttttag ttttcaaaga
     2941 tcagaccttg ttgtaa
//
LOCUS       DADGHT010000172         2833 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.178, whole genome shotgun sequence.
ACCESSION   DADGHT010000172 DADGHT010000000
VERSION     DADGHT010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2833
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.178"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            85..972
                     /locus_tag="JX887_002767"
     CDS             85..972
                     /locus_tag="JX887_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAX1258691.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="JX887_002768"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="JX887_002768"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAX1258692.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="JX887_002769"
     CDS             2274..2720
                     /locus_tag="JX887_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAX1258693.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
BASE COUNT          950 a          454 c          612 g          817 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tat
//
LOCUS       DADGHT010000173         2815 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.179, whole genome shotgun sequence.
ACCESSION   DADGHT010000173 DADGHT010000000
VERSION     DADGHT010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2815
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.179"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..903
                     /locus_tag="JX887_002770"
     CDS             <1..903
                     /locus_tag="JX887_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAX1258694.1"
                     /translation="GFTKQSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSY
                     PLVGPATWDGKVYVQNLFNAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGF
                     KACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESL
                     IGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGW
                     KVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELG
                     MICGKLDRQYYSASAISSIVIPPK"
     gene            916..1824
                     /locus_tag="JX887_002771"
     CDS             916..1824
                     /locus_tag="JX887_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAX1258695.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            1824..2444
                     /locus_tag="JX887_002772"
     CDS             1824..2444
                     /locus_tag="JX887_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258696.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            2448..>2815
                     /locus_tag="JX887_002773"
     CDS             2448..>2815
                     /locus_tag="JX887_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258697.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTT"
BASE COUNT          960 a          432 c          657 g          766 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga catttacaaa tggacaatgg atgggcgtag tacaacctac gacggttgat
      301 ggatttaagg cctgtactga tccaagacaa gcagcatatg cttttgaacg aaactatgaa
      361 cgtccggcag cgacacatcc tgaacgtcaa gattatgcag ttaactggta taacaaattt
      421 aaagatttaa aaccaggagg agctactgga gaagcaggac taaaacattt agagtctttg
      481 attggacaac gaattggcaa tggtcagtgt tatggcttgt ctgcagaata ttcaggatat
      541 ctgggtggtt gtggcatggg tgctggaaca aaatatggtt taactcatgt gataggaaat
      601 acttctgcag catctgatat tggtattgcc tatgattggt ctgctgttgg ttggaaagtg
      661 attcaaaacc ctagatatga tcaattagta gttggtgcaa ttattaattg ggcaagaggt
      721 ggacaagtgg gttcatggtt tgcagatgga acttatggac atactggcgt tatccgaggc
      781 ttagctaatg gtcgtatgca aacttatgaa caaaacacag agttaggtat gatttgtgga
      841 aagttagatc gccagtatta tagtgcaagt gcaatttctt ccattgtcat accaccaaaa
      901 tagggaggtg atttaatggc aaagtggaat gtcatattaa gtacaacaga accctataat
      961 tacgtgggga tgattcaagt tcgacaaggc aataagaata cagaggttat ggaagcgact
     1021 atagttgaaa atggtcttcc ctacgattta tcagaatgta aggtatattt tgaatcagtt
     1081 gtaggtggga aatatccagt ccaattagaa acaaaaattg tggatgctaa aaaagggaaa
     1141 attaactata tttttgataa atattccatg cagtgtttac atcgacaaac agccaatttc
     1201 attatattta aaggagaaga cttgattgga acaactcaag acttctctta ttttgtcatt
     1261 aatgctgttt caaaaacaga aggagaaatg ggttcttatt ggcaatcaat cgaagattta
     1321 attgcggata tgacggactt tattaatgaa aataaaggcg attttacgga ctggatgaat
     1381 gaaaggaaag aagaatttga acgttggaga caagaacagg aacacagttt ccaagattgg
     1441 agagaaggac aagaatcaga ctatttggca tggtttgaat caatcaagga tattttaaag
     1501 acgattgatc caggtggagt catgttagcc gaactaacgg atgcgcgagt agatattcaa
     1561 ggagttcgtc atgcgtctat ttcagagcgt ttgctggcag atatggacta tttatatcag
     1621 aaattgcgag caacgctttt cacgattgaa tacggggaga ttgaagtgac tgatattttg
     1681 caggatgatc tcttttcaga taatcatgaa gtcgaaaaag ttggaactgt agcattcccg
     1741 attgaagaag gagccttgat catcgcaacc gttgatgatc caaagcaaaa tgtgttcact
     1801 cttgagaaag ttggggtgat ctaatggcta aaactaaacg aatgatggaa acggatgaaa
     1861 aaacgggtgt acaacgccaa ttctttccaa tcacacatgc ttccgcagtt cttgggttag
     1921 aagaaataat agcaggagaa gcaacagttt tatctgttaa tggaaaaatt ggagccgtcg
     1981 tcattactaa agaagatttg ggattagaga atgttctcac agaattaccc tatgcaagtg
     2041 aagaagatga cggcattatc acggcagaaa tgtatcaaaa aattttaaac agtggagaag
     2101 gtgactacgt gttgccagtt gccactatcg accgtttggg tggcataaaa gttggtgaat
     2161 tattgacgat tgatgagaca gggaaagtct ctgcagtcag acaatctgat gtcaattttt
     2221 cgctggagtt aaaagaaaaa ctcgattcac tgaaaaatta tactgctgga gaaaacatca
     2281 ctattgatga agatggaaca attagttcta caggtggtag tgggactggt ggtgtcaatc
     2341 agtcatatgt agatcaaaaa ttccaagaag ctgtaaatca agcagaaaat tacacaaacg
     2401 aaagaattcc aaattttact tttgaaaaaa ttggggaggt atagagaatg acagatatcg
     2461 taaaaataaa acaaagcaat gtacaggttt atccacaaac tcattggaat gctatagaag
     2521 gcaaaccaac aacggtgaag ggagataaag gcgatcctgg ccaagcagca acaattacca
     2581 taggaaccgt ttctagtggt tcaaccgctt ctgttacgaa tgtaggaaca tcatctgcag
     2641 ctagatttaa ttttgtttta ccaaagggag ataaaggtga tcctggaata aatgccacaa
     2701 ctacagctgt agctacaact acagcaaatg ggttgatgtc gtccacagat aaaactaagt
     2761 tggatggaat tgcagctgga gcacagaaaa atccaggtaa tgctacaact acgac
//
LOCUS       DADGHT010000174         2795 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.180, whole genome shotgun sequence.
ACCESSION   DADGHT010000174 DADGHT010000000
VERSION     DADGHT010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.180"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            70..531
                     /locus_tag="JX887_002774"
     CDS             70..531
                     /locus_tag="JX887_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HAX1258698.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            565..1200
                     /locus_tag="JX887_002775"
     CDS             565..1200
                     /locus_tag="JX887_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HAX1258699.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            1313..1948
                     /locus_tag="JX887_002776"
     CDS             1313..1948
                     /locus_tag="JX887_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258700.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            2247..>2795
                     /locus_tag="JX887_002777"
     CDS             2247..>2795
                     /locus_tag="JX887_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1258701.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVE"
BASE COUNT         1137 a          399 c          472 g          787 t
ORIGIN      
        1 aacacgggct ctttcctcat atatgagctt ctacaaaaaa aatcatatca cagaaatgag
       61 gaagaaaaaa tggaaaaaga gattttaata aaatctccag gaaaaacctt gattaaagta
      121 actgatgatt ctatttcaat tattagaaaa ggatttataa atttagttaa tcaaggtatt
      181 aaaggagaaa aaactatccc ctttaaaaat atatcagccg tacaattaaa aaaaccaggt
      241 atgagtaatg gttatataca atttaccttg ctaggcggaa acgaaagtcg cggaggtata
      301 ttagcggcca cgaaagatga aaacaccgtt atgtttacaa aaaaatattg gaatgaaatg
      361 gaaaatttaa aaaaatatat agagaagcaa caatctatat tagataataa ttccaaagaa
      421 acacaaattt caagtgcaga tgaaattaaa aagtataaag agttgttaga tgaagggatt
      481 attaatcaag aagaattcga ttttaagaaa aaagaattgc ttggtttata atattcaata
      541 tcaaaagaga aagaggatct attaatggac ggtatatttg gttttactgg tattgtttta
      601 tttattatag gtttaatcat gttaattgta agatttatca aaaaaacaaa taagaaaaca
      661 cctatgattc tccttattat cgggattatt tttactaccg taggtttctc gctttcctca
      721 tcaaacgagg caaatgacaa taacaaacag gaaagctcat catctgatac tcaaactact
      781 acatctaaca gcagcaataa aagcctaact caatttgaag aatttttaga gacaaataat
      841 catgactggg gtgctttctt agatagttat tattctatta ctccagctac tgagcaaaat
      901 acagctttta ctaaatatat tagtggtaaa acatatactt ttgaaggaac tgttatcgaa
      961 tcaatgacta ctagaatagc cattatagca gacaaagagt acgatgataa aagttggaat
     1021 gatatttctg caacacctaa agtttcatat gtaatttttg cgaaggactt aaacaatgct
     1081 gataccttta caaagggcga taaagtaact tttacaggag aaattagttc aagaggatcg
     1141 aacatagaaa aatcctatgc tcaatgggat atgattaata gtaaagtaag taaaaaataa
     1201 atgaaccacg ccccactaag agttagattg tgcacaataa taaaacctat acaaaagagt
     1261 gccatcagga gtcacaatgc ttgtaaagga aatgacaaaa taggaggtaa ctatggataa
     1321 tagcaatgaa aaactaacca aaaaagaata tcttgaatta atagttgaag gcggtattgg
     1381 agcaattcct tatattggtg gcgttgtgca gtcactttat tttgggtcta aaaacgagaa
     1441 gcgtttcaaa cgcatcgaga aattctacaa aaatttaaac gaatcattag aaaacattcg
     1501 cgatcaaatt ccagaagatg ttttcaactt agagaacaag gaccaactca ttggaatatt
     1561 cgaagggata aatgacgagg tagaaaaatc aaaggcacaa aataaaatag atatgtataa
     1621 aaatctttat aagaattgtt tacttcgaat taacaacgct tcatgggata acgaggagta
     1681 ttatcttctt gtactgaatc aattaacatc gattgagatt caattgttag catgcttaat
     1741 gagtcgtgga aacgaaaatt tcactggaaa tatcagcatg tctggctatt cacaagagct
     1801 aatagatggt agcttaaata gattatctga ttttggtctg ttagaaaaaa cgattagctc
     1861 catagtatta ggtgatgtcg gcaaacaaaa tatgggctac aaaatatctc atttaggaat
     1921 tcaatttatt aactcaactc ttacttaagt tttctttcta atatgacatc tagacctatc
     1981 agcaatgcaa caataaaaaa ccagacatac caataatcaa caaataatct aaactctgga
     2041 agttcagtta ttcttttaaa aatcacttta atcataataa acacctctga ttggatgatc
     2101 taatacacat ccaattatac cattaaaacg acaaatagca catccttgcg ccggcaagca
     2161 aaaaggatgt gcaaaaaata ataaaaccca aacaatgggc ttctttatag ttcctattgt
     2221 atcagagaaa gagagctgat tcaattatgg caagattagt caaacgtgga aatagttggc
     2281 aatacgaaat ttcatacaaa aaagatgacg gaaaatacac gaagataaga aaatcaggat
     2341 ttaagacaaa aggagaagca aaagatgccg ccaacgaatt agaatataac ttgaacaaag
     2401 gccttaaagg ggatcgcaaa aatctattat tatcagatta ctttgaggat tggatgcaac
     2461 tttataaaga aggaacagta tctcctatca cttatagaaa atacgaagat acgttaatga
     2521 acataaagaa atatatgcca gcggtattga tttctgattt agatagagtg ggatatcaac
     2581 gctttttaaa taagtatgct aaagaccatg taaaatctac cgttattaag tttaataacc
     2641 atattagagc gtcgttgaaa gatgccgtag aagaaggatt aattccgttt gatccaacta
     2701 gaaaagcagt aatcaaagga aaagattcat tgaagccaaa agaagataaa tatttagatt
     2761 atgatcaatt taaatcttta atgaaactcg tagaa
//
LOCUS       DADGHT010000175         2762 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.182, whole genome shotgun sequence.
ACCESSION   DADGHT010000175 DADGHT010000000
VERSION     DADGHT010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.182"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            14..565
                     /locus_tag="JX887_002778"
                     /pseudo
     CDS             14..565
                     /locus_tag="JX887_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358527.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(935..1936)
                     /locus_tag="JX887_002779"
     CDS             complement(935..1936)
                     /locus_tag="JX887_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HAX1258702.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(2095..2361)
                     /locus_tag="JX887_002780"
     CDS             complement(2095..2361)
                     /locus_tag="JX887_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1258703.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(2351..2707)
                     /locus_tag="JX887_002781"
     CDS             complement(2351..2707)
                     /locus_tag="JX887_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAX1258704.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT          873 a          500 c          371 g         1018 t
ORIGIN      
        1 tcaaattgaa gaaatgaaaa agtttggcgc tgaaaaaatt tttatcgaaa aacaatctgg
       61 agcgacgatt agtcatcggc cgattttcca ggaagcttta gattttgtca gagagcaaga
      121 tatttttatt gtagaagcca ttgatcgact tggacgcaat tatgacgaga ttatcgattc
      181 agtgaattat ctaaagaaga agaatgtgcg acttattatc accagtttac cgatcatggc
      241 tgaagcaatt ggaaatcctc tcctagataa attcatcaaa gacttaatca tttaaatctc
      301 agccatgatt gctgaacaag aacgtactga atcgaaacga cgccaggcac aaggaattaa
      361 aatcgctaaa gcaaacggcg tctataaagg tcgtcctaag ttatacagtg cagacaccaa
      421 agatcctcaa cgtcgccttg tctataggag tatcgttcag gatcttgaga atggggttgc
      481 tatctcaaag attgcaacag actacaatgt gactaggcaa acaatttacc gaataaaaaa
      541 agaaatcgac caactaattg tatgatttct tttttgaatc acgtaattat taattagctt
      601 tgtcatcaat acagacaatc attttagatt catctagcta agttgattac atttatgtta
      661 aaaagaattt agttaacata aatataattg atgcataaat cgtccttatt taaaggcatt
      721 taacattgac aacttagtat aatgtatctt atgtaaacta ataagatttg aattttattt
      781 tatacacact cgataataga tcaattttat ggtcccccgc atttacgatt gcacaagaga
      841 aacataaagt cgacctatta gcatttcttt tcaattcaaa cattaaaaaa gtttatacct
      901 ctgctactaa aaaatgaaat tatctattta aaatttaaaa cggtaaatct gattcatcca
      961 aattggaaaa tggatcagcc tgtattggag ctttgtattt ctccataata acagatatct
     1021 ttttttcatt ttttaaaaaa taccttttaa atttcttata gtcctctgaa atcaaaatat
     1081 agcgtgatgg atactcatca aaagaagaat cgtattcttc ctttaaaatt cccgatttac
     1141 ttaatttttc tagtacatca aatactctat cactcaagta actccttaaa ttgttatcac
     1201 tttcccattg aactactttt ctataagttg aattatcagt tgaaaagata gaattttcat
     1261 ccataaacgc atatattagc agcaatcttt catcattgtc aaattctatt ggatcaaaaa
     1321 tatctaagtt gtcatcaaaa tctttatcag ttccggtaac ttttttgtta attactgaag
     1381 gtgtcttgta agaaatagaa tctaaatcaa agcgttttga ttctaaatta ttttgtgctt
     1441 tctcaattaa ataattcact ttttttgtga gaaaccttct gatattgtct ttgctatatg
     1501 ttccataaaa acccttatct tctaaagagt ccctgtactt cttaacttct atatactctt
     1561 cagccaaaac ttgtggaact ggttcatcta agaaaaaaac ccctacctcg cctttgctat
     1621 ttttataaaa gtaatcaatt tctgctatag ttcccgatct ataattatca actggagaac
     1681 ccaacttatg gccaaaaatc gctaataata tatcactatt ttctacaatt tgtttattaa
     1741 taacactttg cccagagcta ttatttatat aagtaggaat cgcattcgtt tcccatcgaa
     1801 ttggcatcaa aattactttt gtattatctg tattttctat attccatcta tatatggttt
     1861 cttctacttc attcctcttt gctgctatat cacctggtga tgctataaat acttttatta
     1921 gatttatggt tttcatttat tgtacctttc tctttatgtc tctttaaagt aatttttgta
     1981 taaaatttat tgacttttac actataggac aacttttatc tatttagtac aaaaaggccc
     2041 actaaactaa ttgattagtt aggagcctat tacaggtata ttttcaactc gcttttaagc
     2101 aaattctact accagctttt tgcctaatgc cctagcgata tcatcaagtt tatcgaaaga
     2161 tacgttatcc cctctctcaa ttcgagcaat agtagattga gttgtatgtg ctttttgtgc
     2221 aagctccgct tgagttaggc ctgcttcctc ccgtgcatga taaagagcaa ccgcagtttc
     2281 gagttttctt ccttcacggt catatgcttc tgcaaaatct ttgtcttttt gcttttcttc
     2341 aatcaatttt ttaatcatca tttgtgaacc actcctctct aagttctttt gcatgtttaa
     2401 gttcacttat tggtgttttc tccgtttttt tagtaaatcc atgggtaatg acataccttc
     2461 cattgaccac atggaaatag atagctcttt ggatgtttga tcctacctta cttcttaatt
     2521 cgtacaaatt agtgtctaat tttttcaccc atttcaaccg ttgagctact agcatcccat
     2581 tcttttctgt ttcttctatt gtacgtaaaa gcttcgcact atcttttttt ggtaatgttt
     2641 ccaaccattc taaaaattca tcatgaccat taggtctttt aaatgtttca aaagatattt
     2701 tttccatacc caattatatc atatattgat tttatattat agtatataac ataaaaattc
     2761 ga
//
LOCUS       DADGHT010000176         2739 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.183, whole genome shotgun sequence.
ACCESSION   DADGHT010000176 DADGHT010000000
VERSION     DADGHT010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.183"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..156
                     /locus_tag="JX887_002782"
     CDS             <1..156
                     /locus_tag="JX887_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HAX1258705.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
     gene            175..1452
                     /locus_tag="JX887_002783"
     CDS             175..1452
                     /locus_tag="JX887_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1258706.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1462..2118
                     /locus_tag="JX887_002784"
     CDS             1462..2118
                     /locus_tag="JX887_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAX1258707.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2118..>2739
                     /locus_tag="JX887_002785"
     CDS             2118..>2739
                     /locus_tag="JX887_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258708.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGL"
BASE COUNT         1162 a          252 c          469 g          856 t
ORIGIN      
        1 gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat
       61 tcagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt
      121 ccagtggatg caattagtta tggagtaaga aaatagagag gagtagttag gaaagtgata
      181 aaaaatgcta tagcatatat tacaagaaag aaaaatagaa ctttaataat ttttatcata
      241 ttaactatag ttctttcttg cttgtattct tgtttaacaa taatgaaatc aagcaatgaa
      301 atagaaaagg ctttatatga aagttctaat tcttcaatat caataacaaa aaaagatggt
      361 aaatatttta atgttaatca atttaaagat attgaaaaat taaaagaaat tgaagaaaaa
      421 ataattcaat atgatggatt agcaaaacta aaagatgcta aagtagttag cggagaacaa
      481 agaataaata gagaagattt atctgacgaa tttaagaatg ttgtttcact cgaagctaca
      541 aataatacta aaagaaatat tttatttagt agtggagtat ttacaattaa agaaggtaaa
      601 aatatagaag aaaatgataa gaattcaatt attgttcatg aagaatttgc taaacaaaac
      661 aatctaaaat taggtgatga agttgatctt gaattactag atattgaaaa aagtggaaaa
      721 ataaaaagtc ataaatttaa aattataggg atcttttctg gtaaaaaaca ggaaacatat
      781 acaggattat cttctgattt tagtgaaaat atggtgtttg tagattattc aacaagccaa
      841 gagatattaa ataattcaga aaataatgaa attgcaaata aaattttaat gtattctggt
      901 agtgcagaat ctacagactt agccttaaac aaattgaaag agcttaaaat tgatgagtca
      961 aagtattttg ttgaaaaaga ttctaatgcg tttgaagagt ctttagagtc agtgagtgga
     1021 ataaaatata taataaaagt aatgacttat tctattatgt taggtgggat ggttgttctt
     1081 tcattaatct tgattctatg gttaagggaa agaatttatg aaataggtat attcttatct
     1141 attggaacat ctaagataca aattataatg caatttatat tcgagttaat attcatatcg
     1201 ataccaagta taatatcttc cttattttta ggaaatgtat tactaaaagt aattgtagat
     1261 ggattcatta actcagagga ttcaatgatt tccggtggaa gtttaataaa taatagtagt
     1321 tttatgtcaa atataacaac acttggacaa agttatttaa tattaataag tattattgtt
     1381 ttatcagttg tatttgcttc ttcattaatg ttaatcaaga agcctaaaga aatcttatca
     1441 aaaataagtt aggagaaaat aatggatata ttagaaataa agaatgtagc atatagttat
     1501 gcaaattcta aagaaaaagt tttgtcagga gtaaatcaaa aatttgaact tgggaagttt
     1561 tatgcgatag taggaaagtc aggaacagga aaatctacac ttctttcctt acttgctgga
     1621 cttgataaac ctcaaacagg aaaaatattg tttaagaatg aagatataca aaataaagga
     1681 tatagtaatc atagaaaaaa taatatatct ttagtatttc aaaactataa tttaatagat
     1741 tatttatcac caattgaaaa tattagatta gtaaataaat cagcagatga aagtatcttg
     1801 tttgaactag gtttagataa aaaacaaata aaaagaaatg ttatgaaatt atctggtgga
     1861 cagcaacaaa gagtagctat tgctagagca ttggtatcag atgctccaat aatactagct
     1921 gatgagccta ctggtaatct agacagtgtt actgctggag aaataattaa tatattaaag
     1981 acattagcta aagatagaaa taaatgtgta atagttgtaa cacatagtaa ggaagtagca
     2041 gattctgcgg atatcatttt agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg
     2101 aatttggagg ttgaataatg ataaaaaatg catttgctta tgtaactaga aaaagtttaa
     2161 aatcattaat tatcatatta gttattttat ctatgtcaac tttaagtctc attagtttat
     2221 ctattaaaga tgctacggac agagcttcaa aagaaacatt tgctaatata acaaatagtt
     2281 tttctatgga gataaataga caagtaaatc caggaacacc tagaggtggg ggaaatgtaa
     2341 aaggtgaaga tattaaaaag atatctcaaa cagatagtat agactcctat gtaaaaagaa
     2401 taaacagtgt tgcagattta gttgattatg atattattga aactcaagag actcttgcga
     2461 atcaatcacc tgaaagagca aagaatttta aaagaacagt tatgttaact ggggttaacg
     2521 actcaacaaa agaaacaaaa tttgtatcag aagcatataa attagtagaa ggaaagcatt
     2581 tagaaaatga agataaaaat aaaatcttaa tgcataaaga tttagctgaa aaaaataacc
     2641 ttaaagttgg agataagata aaaataaaat ctaatttatt tgatgctgat aatgagaaag
     2701 gtgcagatga aacagtagaa gtagaaatta aaggtctat
//
LOCUS       DADGHT010000177         2676 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.184, whole genome shotgun sequence.
ACCESSION   DADGHT010000177 DADGHT010000000
VERSION     DADGHT010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.184"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            44..367
                     /locus_tag="JX887_002786"
     CDS             44..367
                     /locus_tag="JX887_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258709.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            531..785
                     /locus_tag="JX887_002787"
     CDS             531..785
                     /locus_tag="JX887_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258710.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            855..1100
                     /locus_tag="JX887_002788"
     CDS             855..1100
                     /locus_tag="JX887_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1258711.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            1176..1541
                     /locus_tag="JX887_002789"
     CDS             1176..1541
                     /locus_tag="JX887_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258712.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1602..2165)
                     /locus_tag="JX887_002790"
     CDS             complement(1602..2165)
                     /locus_tag="JX887_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258713.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT          785 a          474 c          422 g          995 t
ORIGIN      
        1 tttgcttatt ttagaaaaaa tgttattctt ttatttattc tcaatgttag gagtgattat
       61 tttgccattt attgcgattt tattcgattt agttgcggca gcagcttatt ttctccaatt
      121 aaattatcaa acctcaggaa ttctgtttat tggaatgatt tttcaaggtg tgattaccct
      181 tttgcttctt gtcatgatgc tcagctataa aggaaaaaga tatgcccgta ttcaaacaaa
      241 agtatttgtt aaatatgttt ccattcgcta tgggatcatc attctttcct ttttagtgaa
      301 tgcgatcgtc ctctttttat atgtattgaa ttacttagat atcaatccat tgattttttc
      361 tcgatagata agacacattc agcggaacag ttcctgctta tcagcagaaa actgttctgc
      421 tttttcattt ttcattgatc tattcttctt ttattttcct agcatttcat ttgtgatgta
      481 tgcaataaca tgttatcttt tattatatga atcgttgagg agtccgttac atgattacgt
      541 tggtgagagt tttgttttgg gtgcctgcgg tcgcactggt cgcaagtatt gtttatctta
      601 tgaattggaa caaagaacgg ttttatttag ctattttgac tcttccggct atctacttta
      661 tgtggaaagt ttttaattac aactactttg aacccgatag tgtttttata gaagaattat
      721 caggactggt tttgtcttta ttgatcgtca ttctttattt gatacgttta aataaaaaac
      781 attgagtact attgattgca tgtgtagctt tctatagtca ttataactat tctactataa
      841 tgaaaggtga ttaaatgagt atcgaagaag ctattttact ggatacttta cgttgtcgtc
      901 tgaatttctt aagaactggc cgatctttat ctcaagtagc tgtttctagc gcgttaagta
      961 ttcctttatt caaatatcgt aagtacgaag aaggagaaga aattccaagc atcattgaat
     1021 taatctatat cgctgacttt tacgatattt ccgttgatta cctaattggt cgctcagaaa
     1081 cagcaagcaa actgaagtga ttttttccag ccttggtgct ggttttttca tttaacgtct
     1141 aaggttaaca atctatatat aaaggagaca tttctatgcg attatggcat gaaaaattga
     1201 tttcaaagct tcctcgtcaa cagcttttag gacaacatcg ggaatgctgt gcattaagag
     1261 gaaatggctg gggaaagaaa catgctactg tggattatgt ttttcactat tctccttata
     1321 gattattcca atatcatcag cttgtcatgg atgaaatgga aaaacgtggt tacagcccag
     1381 caccagagtg gaaaaatcct atgtatcgtg gcaaatcatg cgaagcattt tttgatttac
     1441 ctactgtaga gcgcaacgtg ccgatttatc cggaacacga tgaagtttat ctagcagaat
     1501 gtttagcaaa tttggagcaa aaaggaattt atcttaccta atataactag aaaagccttc
     1561 tatctcctct tacttcatta aaaagcttta accatcttag atcaagctaa aatgtcgtaa
     1621 gttttagggt tatcttcatc ctcacgtgca aaactaaaag cgtactctag ttttggttca
     1681 tcgccaactt ccctagacat aaatgaacat ctcctgacgt ggtttaaaag taccgcatct
     1741 tcgacgtctg tatacgatgc acagcacaga ttgcttcttt tgatctttct tttgattttt
     1801 ctgttgcttc ttctacacct tcttcgatta ctacatcgat gcttacaatt gcttctgcct
     1861 aatattccca tgcatcgtcg atttaagcct ctgtagtcac tgtgatcgtt tccacatttt
     1921 aactcctctg tcgtggcttc agttgatttt gtgatcagtt cagttgctaa gccagagtca
     1981 gaacaacctg ccattgctag cgttaatatt gatagtaaaa atagtttttt tatcataagg
     2041 ttccccccct gaaaatagac taaaataata acgctttctt tttttgtttt cagacgaaaa
     2101 ttaataattt ctaaatattc tttaaaaaag cttataacta ttatgccttt tttaatatat
     2161 aacacagtta tttttaaaaa taagaatgct aaatcactct acaataacgg cgaaagcaca
     2221 aaaaataaaa aaattattac gttattaaaa aaacagatga aagatcaggt tttattagat
     2281 ctcattcttt catcacttga agggatttaa tgaactactt tttcctcttt gtcgttttta
     2341 tatattcgta ttccttcaaa cagtaggata gcctctttca atgcttgata tttgaactgt
     2401 ccgttactta aaaatttaga tgtgccgccc tcttcctaga acatattctt ttttactttt
     2461 tcattaattg acagaccaat cgaacgaaac tgtaaatttc gataggataa tgattggtca
     2521 aactcattca ttttcaagac atctcgattc atattcaaga taggaatctt tttatcaaca
     2581 tcactttatt cgtattttcc tctaccataa aagcttcacg ctccacaaaa ttgttttata
     2641 cactactatt cagcccattc aacgaccaat gaattt
//
LOCUS       DADGHT010000178         2590 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.185, whole genome shotgun sequence.
ACCESSION   DADGHT010000178 DADGHT010000000
VERSION     DADGHT010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.185"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(45..1364)
                     /locus_tag="JX887_002791"
     CDS             complement(45..1364)
                     /locus_tag="JX887_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAX1258714.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="JX887_002792"
     CDS             complement(1361..2014)
                     /locus_tag="JX887_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAX1258715.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..>2590
                     /locus_tag="JX887_002793"
     CDS             2302..>2590
                     /locus_tag="JX887_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1258716.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAK"
BASE COUNT          858 a          405 c          252 g         1075 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgaca ccttctgttg
     2101 ccaatacttt ttcttttttc taataaatgc aaacagacac cttgaaatcc tttagaataa
     2161 agggttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tattgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa
//
LOCUS       DADGHT010000179         2518 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.186, whole genome shotgun sequence.
ACCESSION   DADGHT010000179 DADGHT010000000
VERSION     DADGHT010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.186"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..125)
                     /locus_tag="JX887_002794"
     CDS             complement(<1..125)
                     /locus_tag="JX887_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HAX1258717.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYG"
     gene            complement(143..463)
                     /locus_tag="JX887_002795"
     CDS             complement(143..463)
                     /locus_tag="JX887_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1258718.1"
                     /translation="MITFERIKELAKKQGKSLNKVEEDLGYGKNVLYRLKNSNPSTER
                     LQEIADYFDVSVDYLLGREEKETPKHVDLSENDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            1195..1452
                     /locus_tag="JX887_002796"
     CDS             1195..1452
                     /locus_tag="JX887_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="HAX1258719.1"
                     /translation="MNKEMSQTIKVQKMIDDLTHGIDSQADKIIKELQGQKVKDAKML
                     LKTINFEMNPTKRKLADVLEEKLASAINEQELLFETDTFNS"
     gene            complement(1423..1731)
                     /locus_tag="JX887_002797"
     CDS             complement(1423..1731)
                     /locus_tag="JX887_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258720.1"
                     /translation="MKPEFVITMLDGEKIKIFADTLVVGYDDASNIEEKDGMFYSSQI
                     YVNTLQGDIGVSTLATSRPLVGLIGFLSKATFFSLGDDIDSDETVIYKTSAVKSIGFK
                     "
     gene            1809..>2518
                     /locus_tag="JX887_002798"
     CDS             1809..>2518
                     /locus_tag="JX887_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAX1258721.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVADVLGYSNPQKAIR
                     DHVDLEDKTQNDSFTVNGTAVVLINESGLYSLILKSKLPSAKKFKRWVTSEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEG"
BASE COUNT          896 a          447 c          429 g          746 t
ORIGIN      
        1 ccatatagat tttcattcaa aaaaatgatt ctaggcttcg gataatagaa gccaggctct
       61 ttcatttcca tgtaaactac tttcaaattg tattcgctca acatttcttt caatttcaaa
      121 tacatacaac ccatcactcc aactattcat tttcctctaa agctttagcg attgcaatcg
      181 ctttacgcat tgtctcctta gatatttctt ttccatcaaa agaaaaaaca gtatcgtttt
      241 ctgataaatc cacatgttta ggggtttctt tttcttcgcg ccccagaaga tagtctacag
      301 agacatcgaa atagtcagca atttcttgca aacgttctgt agaggggttt gagttcttaa
      361 gtctatataa gacgttttta ccatagccta ggtcttcttc aactttattt aatgattttc
      421 cctgtttttt cgctaactct tttattctct caaacgttat catatcaata ttcctttcgt
      481 tcaagaaaaa atatttaact ttatttgtta aaattcgttg actattttaa caaaaggtgt
      541 taatatcatt cttgtaaaca agtttaacaa ctaaaaagac aacaaaaaac actattgatt
      601 aataaatgcc aaccgccaag aaagctttta aaatcaatgt ttatatgtct tatttaacta
      661 tgttctgatt ttaacactgt atgttaattt agtcaacgca gttttttaaa aagttgttaa
      721 atttgtttac gaatataaaa gaaaggagag aagaatatgg aaaaaacagt ctcggcaaaa
      781 atcgaagatt tgaaattaga catactgaaa caagcaaaag tggcgatgga acacgcggta
      841 gataaagaag actctgccat ggttgcagcc atagcagaga ttttagctca cgtttagtca
      901 tcgtttttac ggtcttctgg aagctgacca tagataacag cataatgaat atctaaataa
      961 gtttgaacaa tttcttttgg cgaaattgat tcgcctttag tagatacttg tgattcgtga
     1021 tttagccatg caacaactaa atccgcagcg atttcaaacg gcgttacact ttgtgtcagt
     1081 tgccataaag aatttcacaa tatgtatggt cgtggtaata ataccaaaga gcaatttgag
     1141 gaatttatgg aaattaaaaa atacaaaaaa tcatttatta aaggaggcta aacaatgaac
     1201 aaggaaatga gccaaacaat caaggtacaa aaaatgatag atgatctaac acatggaatt
     1261 gatagccaag ccgataaaat catcaaggaa ttgcaaggac aaaaagttaa ggatgcaaaa
     1321 atgcttctca agactatcaa ctttgaaatg aatccaacaa aaagaaagct cgccgatgtg
     1381 ttggaagaaa agttggcttc cgctatcaac gagcaagaat tactatttga aaccgatact
     1441 tttaacagct gatgttttat agatgacagt ttcatccgaa tctatatcat cgccgagaga
     1501 aaagaatgtt gcttttgaca aaaagccgat aagacctaca agcggtcttg atgttgcaag
     1561 agtagatacc ccaatatcac cttgcaaggt attcacgtaa atttgagaag aatagaacat
     1621 tccatctttt tcttcgatat ttgacgcatc atcgtatcca acgaccaaag tatcggcaaa
     1681 tattttgatt ttttctccat caagcatagt aattacaaat tctggtttca taaattttca
     1741 cctccttaac aattatttca gcctgtcaca ctgataagga aattatacca aagaaaggaa
     1801 tgagaaatat gaatacacca caaattttta atttcgagca aaacgaagtt cgaactattt
     1861 tagtaaatga tgaaccatat tttgtaggaa aagatgtagc agacgttcta ggatattcga
     1921 atccgcaaaa agctattcga gatcatgtgg acttggagga taagacgcag aacgattcgt
     1981 tcaccgtcaa tggaacagca gttgttttga ttaacgagtc aggcctttac agtttaatct
     2041 taaaatcaaa acttccctct gccaaaaaat ttaaacgttg ggtaacgagt gaagtccttc
     2101 caacaattag aaaaacaggt agctattcaa acgtacctca aagttttgca caagcattgc
     2161 gtttagcagc ggatttagaa gaaaagaacc aattactcga acaacaaatt gccgagtacg
     2221 aaccaaagat tagctactta gatacgattc tttcatcgac agatacggta gctacttctc
     2281 aaattgcagc tgattacgga atgtcggcaa ttgctctaaa caaattgcta aacgagttag
     2341 gtgttcagca taaagttagc ggacaatgga tactttaccg aaaacatatg aaccaaggat
     2401 acacaaaatc gcacacaagt gagataccga aagccgatgg cggcactaaa gttgtaatga
     2461 ataccaaatg gacacagaaa gggcgagtgt ttatttacaa cttattaatc gcagaggg
//
LOCUS       DADGHT010000180         2438 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.187, whole genome shotgun sequence.
ACCESSION   DADGHT010000180 DADGHT010000000
VERSION     DADGHT010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.187"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(188..805)
                     /locus_tag="JX887_002799"
     CDS             complement(188..805)
                     /locus_tag="JX887_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258722.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
     gene            complement(867..1547)
                     /locus_tag="JX887_002800"
                     /pseudo
     CDS             complement(867..1547)
                     /locus_tag="JX887_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(1869..2090)
                     /locus_tag="JX887_002801"
     CDS             complement(1869..2090)
                     /locus_tag="JX887_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258723.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(2188..2433)
                     /locus_tag="JX887_002802"
     CDS             complement(2188..2433)
                     /locus_tag="JX887_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258724.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
BASE COUNT          721 a          470 c          349 g          898 t
ORIGIN      
        1 aaaaggaaaa cgtagaaaat tacgtctacg ttttcctatt tagttctata ttttcattaa
       61 attttatatt tgctcttttc acttttcgga ataaattcac tgtgactctt gataccttct
      121 tttatatatt gctaatgtat tttctccatt gctatgaaaa tagaatcaac atatttataa
      181 tatctatcta atctattttc atttcaccgc agcatcttat taaataacgt gtaaataaga
      241 atataaaagt tattgaacta attaataaag atagaatcat cgtagttgga tacgtagatg
      301 aaacctcaac tatagttctt ttccccgtac ctttaataga cactaaacca ttgtcatttt
      361 ctatagtgct ctttttccca tttactttca caactgttcc ccaataattg aatacaggta
      421 atgtgatatt ttgctcatcg gcatcttcta ctgtatagac tattttggaa ttatatgctt
      481 tatgagatgc attctcccac cgatcaccaa cttttacttc atgtttcttt aaatgatctt
      541 tatatttcaa tgcatctaat ggtgcatagt catataggcc tccagttctt gaggatgtat
      601 aacgtgtaac atcttttttg gtcataacta aacgaccttt atacgactga attttatgcg
      661 aataatttgc ttctgttgct gcagtcacag taaaaataat aagaactatt cctacaaggc
      721 tccacatact ttttttgttg cttgttttcc actttaaaaa cactatggtt aagattaatg
      781 aaccaaaaag cacttgaaaa cccaaggttc tcggttctgt tgcgaagttt gaaaatcaaa
      841 cgcgccctct ctgaactcca aatatcttag gctgttattc ccattaatac cttgatttca
      901 gtagacaccg aaaagccgaa gagcgttcca tttcttcggt tctttttata tattcctcga
      961 atggtctcca tgcccttaat cgtggaagag gctgtacgga gactttgata aaatttattt
     1021 cgtcgtttaa taggtcgatg gtcttgttct attaaattgt taagatactt cacagttcgg
     1081 tgctctgtct tagtatataa acccacactc tgtaactttc taaaggcgga gccaagagaa
     1141 ggtgctttat cggtcacaat tgctttcggc tcaccaaact gtttatggag tcgttttaag
     1201 aaagcatagg ctgcttgcgt atcccgtttc tttcgtaacc agatatctaa ggttaagccg
     1261 tccgcatcaa ttgcacgata aagataatgc caacgtccct taattttgat ataggtttcg
     1321 tccattttcc atgaatagaa ggattgtcta tttttcttct tccaaagata atagaggact
     1381 ttgctgtact cttataccca acgataaatc gtagtatgac aaacatttat tccacgatca
     1441 tataacaatt cctgaacttc acgatagctt agattgtaac gcaggtagta accaacagcg
     1501 acaataatga cgtctttttt gaattgtttg cctttaaaat gattcattac tctgtcctct
     1561 ctgtcttttt tctcaatttt acactaaaat agattttttg gaaaactttg caacagaacc
     1621 gtttttacta tatacttctt cccagaactt gtccgtctcc ttcaaattat ctctacctct
     1681 cgagttcatt gggtggtttg cccatttatt aaacatggaa tcacctttct catactcata
     1741 tatttatgtc ctatttcaat tatatttata tatgcttaaa taaatttgta tcctgaaatt
     1801 tattgtaata tgaagctgta ttttacatat agtaaccaaa gagttaataa aataaaaaga
     1861 gcgaaccatt atagatcagc tcttttttca ttgctgtttt taatcttatc tagaatcact
     1921 tcaaatgttt caaaggtatt tacatctaac tgacataacc aaagcaagta cttcttttct
     1981 ttgtaagtcc aatcaatatt acggtaagag gacattagat tatggtacct tgctctttgt
     2041 tcaactgaag ccaattccca gcgtttttca aatatttttt cttcttccat tattgatccc
     2101 tcgcaagacg ctacctcaaa cttaaataat gggcagcgaa agtctaattc cttagatcta
     2161 agtatagcaa acaaatatga aaaaaactta gaaggtagta aaagttcttc cgtcttttgc
     2221 tttgcttcta ttcttaatgt gtttcgttat cggtgcccta caaagatttt cattaattac
     2281 acactcattt attgttgtgt attttctgac atttctctct tgatcaatta ttttaattcc
     2341 atgggcatcc tgatagttca taggagagga gcggctatca gaaatagttg cacctatctc
     2401 ttgaacttct tttacaactt ctggaaaatc catccatc
//
LOCUS       DADGHT010000181         2398 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.188, whole genome shotgun sequence.
ACCESSION   DADGHT010000181 DADGHT010000000
VERSION     DADGHT010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.188"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            207..2069
                     /locus_tag="JX887_002803"
     CDS             207..2069
                     /locus_tag="JX887_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1258725.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="JX887_002804"
     CDS             2069..>2398
                     /locus_tag="JX887_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAX1258726.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DADGHT010000182         2374 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.189, whole genome shotgun sequence.
ACCESSION   DADGHT010000182 DADGHT010000000
VERSION     DADGHT010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.189"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            342..579
                     /locus_tag="JX887_002805"
                     /pseudo
     CDS             342..579
                     /locus_tag="JX887_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(723..1499)
                     /locus_tag="JX887_002806"
     CDS             complement(723..1499)
                     /locus_tag="JX887_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAX1258727.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            1622..2029
                     /locus_tag="JX887_002807"
     CDS             1622..2029
                     /locus_tag="JX887_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAX1258728.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT          822 a          381 c          360 g          811 t
ORIGIN      
        1 ttgagctaat accgaaggtc agctgattga acaccgttta agaaagaggt cgtgagcctg
       61 tcatttaact ctgagtcaca agtaacaatt tcaaaaaaca gcttctcatc tttgatgaat
      121 atcgtgactt gtggacgagg cgttgataag tgaatcatct ttttgttacc tattttttct
      181 gtaaccaaaa aacgatggaa cgttgttttg attgccctta atgaggacag tcggaacagg
      241 tttgtcattt ttatatttaa atggcacaaa tttttctaat tatttgtcat ttagcgctga
      301 aaatttttgc tatttatcta aaaaagtgat aactacttaa gatgaagcag aatatttacg
      361 ccatacggca tacaaccgcg aaaaatataa aaaaaagaaa acgattgaac gcgtttttgc
      421 agtcgcaaag gaaaagcatg gaatgcgcta catcaagtat cgagacttgg aaaacaatca
      481 ggtgtatacg ctgattgttt ttgctgcaat gaatctgaaa aagttgtcca cttggcagtt
      541 ggaacatatg tcttcatatc ttttattata caaaaatagc aaaagcacca gtctacactc
      601 ttagtaaaga ggaaactgat ccttttgtct acattcttaa agtacttaaa ctaagtactt
      661 tattttactc tttaggattg atacagtagc atctatccct ttattaataa tcttttattt
      721 ttttaaataa agatgttgtc tccatcttca ggcactaaaa ctttttcgga aattcctttt
      781 tctttattga aagactttaa ttcttctctt gacagtcccc aatggtttac agcttccata
      841 tgaacggcaa taattgtgga atctggtatt gctttatgca attcatataa atcgtctttc
      901 cccataataa gagattctcc aactaaaaaa tgattatctc cagcatttgc tactatgatt
      961 tctggattat actgatcaat agtttgttta acagcttcat accaaactgt atctcctgta
     1021 aagtatagtg tcttctcagt cgaatgtttg aaaacaatac cgcaaacatt acctacataa
     1081 ttcaagattt ctcctctgcc atgtttgcct tttgttttaa ccaattgtat agattcaaaa
     1141 actgtgtctt ctcgtagtac ctccacattt ttaaaaccat atagtcgaat ttcattcgca
     1201 tcattttcat cttgcacaaa taattttatt tctttaggta ggacctcttt cgctatatcg
     1261 tcccaatgat ctagatgtaa atgtgttaca ataacagcat caataccgtt gataatatct
     1321 tcgactggca ttggcaaatc aactagagga ttcatttgat cttttcttgg tgatggaaaa
     1381 ggacctttcg aaataaatgg tggaagtgtt cctttttccg ctaacattgg atcaattaaa
     1441 aattttttac ctccatagtc taagatagct gttgcattac gaatgtgatg tatattcata
     1501 aacgttgtct cctttttgtt gatatgaaat atttttagta taattcaatt ccatacaata
     1561 aataaaccga acaaaaaaag tcttttacta tttttactta atttatgaaa ggttgtttac
     1621 catgttagac caaacagata taaatatcat tgaggaacta tcaaaaaata gtcgaatcac
     1681 aatgaaagaa cttggagaaa aagtacattt gactggaccc gctgtctcgg cgagagtgac
     1741 aaaactagag gaaagtggag ttattgaaaa ttatacagta aaattaaata tggaaaagct
     1801 agggttttcg attcacgctt ttttaattat aattacgcaa aatttaaatc ataaacccta
     1861 tttatcattt attaaaaatc atgaaaaatt cttgattaga aattataaga ttagtggagg
     1921 gggctgttat cttttggaat gtagatttac ttcaaaaaaa tcaatgaaca gctttttgga
     1981 acagcttaat gaatatgcga attataaatt atctattgtt atagattaat aataaaacta
     2041 gcagatggta aaaatactaa tatgcgagac acacattcaa ccataactat ataacttatc
     2101 aatttaaaac taaactgatg gaaacaagta aggcaaaaac atttatattt tgccctactt
     2161 atttttttaa ttaaattcat tgatgattca tatttagaaa attctatgaa ggccaaatga
     2221 gtatcctgtc acttttttag ataaatagca aaaattttca gcgttaaatg acaaataatt
     2281 agaaatattt gtgccattta aatataaaaa tgacaccaag tatatcatga acgcacaaaa
     2341 agaccaacag ggtataccct gttggtctaa ataa
//
LOCUS       DADGHT010000183         2364 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.190, whole genome shotgun sequence.
ACCESSION   DADGHT010000183 DADGHT010000000
VERSION     DADGHT010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.190"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            150..1451
                     /locus_tag="JX887_002808"
     CDS             150..1451
                     /locus_tag="JX887_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAX1258729.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            complement(1555..1755)
                     /locus_tag="JX887_002809"
     CDS             complement(1555..1755)
                     /locus_tag="JX887_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAX1258730.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT          768 a          453 c          408 g          735 t
ORIGIN      
        1 cgtacaaaaa aaccgtcttt tcttggctct ataatttcta ggactgatag aaaatcattc
       61 tatcggtccc ttttgagcat gaaaaaacaa aacatacaga agctccgtta gaattgaatc
      121 accacaacac aatcaaagga gcgttctgta tgcctgatct tcatcatatc aaactactac
      181 ttggaatcaa agataaaaac attttcatca caaatgtgga atcgaagagc attaagaata
      241 tcaagagtct tgttgtttct gcgacgttaa gtaaagaaat tcgtcgctgt cctttgtgta
      301 aacagatgaa tcatgaaggc atgatcgtta agaacggaaa gaaaaaatcg ctcattcaac
      361 ttaataaatg tgcgaaccaa ctgacttatc ttgctttagc gaaacaacgc taccactgtc
      421 gtggctgcca cacctatttt acggcgaata cctacattgt cgatagaaac tgctttatcg
      481 ctaaacaagt gcgctataaa attttagaag agctaactga aaaacaagca atgacgacaa
      541 ttgctaagca ttgcggcgtt tcttggtcga ccgtttctcg gacactcgct tctctgatcc
      601 ccatgacaaa agtaaaaaga aattggttac cgcgttgttt attaatggat gaatttcgtt
      661 cactgaaaaa tcaagtcggt ccctactcct tttcttgtat ggatggcgat actggaaaat
      721 tactggatat tcttccttca cggaagaaaa aggctctcgt ttcttatttt atgcaatttg
      781 aacgacgcgc acgattgaag gtaaaggtca tcgtgacgga catgaatgtt tcttatgcct
      841 ctctgataaa ggaatgtttt ccaaaggcaa aactcgttgt ggatcgtttt cacattgtca
      901 aacatctcat tcgtaaattt gaggatattc gcgtacgaat catgaaaagc tttgatcgaa
      961 acgatccaac acaagccaaa tattatcgac aattaaaggc gttgtctcgg cttctgatca
     1021 aacgacagga caagcttgtt tatgacaaat ggaccaaatg gcgcaatttt ggttgggcgt
     1081 atctcaccga aagtgaagtg gtggatcgtc tgctttcgat ctctgacgaa ttacgaatcg
     1141 cctattttta ctatcaagaa attcttcaag cgtttcacga caaagaggcg gacactttct
     1201 ttaaacttgt aagaacgatg cccaattccg ttccaaaaga actgcattct ataaaaaaag
     1261 cttttataaa ctatgaatcc ggcattcgtt tagccctcga attgccttat tcaaatgcca
     1321 aaatagaaaa tctgcatacc cacatcaaag cattgaaacg agtcgcttat ggctttcgaa
     1381 gctttcggaa aatgaagacc agaattttct tactaaataa tctgattacc tatgaatcaa
     1441 aaaacatcta aagtagaaaa ggaattctac cttagatgtt cttatctcac tctatcagtc
     1501 ctatttgaca aagagccctt ttctttcgaa aagacggtta aaagtcaatt tttattaagc
     1561 tttaacaatg tttgttgctt gagggccacg ttgaccatct tcaacatcgt aagacactgc
     1621 ttggccttct tctaaagttt tgaagccgtc accttggata gctgaaaaat gtgcaaatac
     1681 atcatttcca tcttcaccag tgataaagcc aaaacctttg tctgcgttga accattttac
     1741 tgtaccgtta ttcataaata aattcctcct gatacgtatc aatgtacgtt ttttcgttgc
     1801 aataaatatt tgataggcaa aaggagtttt atctatgtag atatatcgct caaattacgt
     1861 ttcaaaatag attactcatt taatatatca tgctttttct aataacacaa ggataatgca
     1921 atgaaatata aaattcattg tcttctattg tcttcgaatc gaagaaaaag ttgaataacc
     1981 gcgattgatt cactttttgt tttcttgttt atttgctttt atctgcaact tttgacttta
     2041 aaatttctta actatgaaaa cctttcaatt ggtggtatac ttataaatgg aatttcgtta
     2101 tcaacgcgtt cgttgccttt cagcaagtat ttaaagaaag gagaatggct atgacattct
     2161 ataacaaaga tatacaatat cgagtaacct tggatacaga tttgaatcta tttgtcgttt
     2221 ttgacaaaga aaataccaat catgtagcga caggtgttac gatcgaacaa gcagtgcaag
     2281 aattaaaaaa atctgcataa ggagtggaaa ccctcatatg gacgattctc gttcttctct
     2341 ttaaacgcat ctactggtag ataa
//
LOCUS       DADGHT010000184         2362 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.191, whole genome shotgun sequence.
ACCESSION   DADGHT010000184 DADGHT010000000
VERSION     DADGHT010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.191"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(110..910)
                     /locus_tag="JX887_002810"
     CDS             complement(110..910)
                     /locus_tag="JX887_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAX1258731.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            1134..1349
                     /locus_tag="JX887_002811"
     CDS             1134..1349
                     /locus_tag="JX887_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAX1258732.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            1488..1973
                     /locus_tag="JX887_002812"
     CDS             1488..1973
                     /locus_tag="JX887_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258733.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
BASE COUNT          679 a          453 c          364 g          866 t
ORIGIN      
        1 ttttgatttc tttttgcact tcctggattg aaactttctt gtgagtgact agtaatttca
       61 ataattggta ccatctgttt actagcgtca cgtgcgtccc ccctatcctt tatcctcttg
      121 ttttacctcc tgaaatatta gtcgtgactc cagtgatata acttgatctt tctgaaagat
      181 aatagcagac tagatccgcc acttcttgca gcttaccact ccttcctaga gggatcgtac
      241 ttgttcgact gtaaccgttt ctcagctgtt cgacgcttat acctctcgta taagaaagag
      301 cttcttcata ttcttgtgtt ctcaaaccgg tttcttccag tatccctggt gcaacaccta
      361 ccacacgaac attcctcttt cctaactctt ttgcccaaga acgagtaaaa ctgttcatcg
      421 ctgcttttgt agcagcataa cagctctgtc cttctgatcc ttccaatcct gattcagaag
      481 aaagattcac gatcactcct gatccctttt gcaccaagat tcttccaact gcttggctca
      541 tcaaatatac acttttttga ttgacagcga tcatcttatc aaaaacttgt tctgataatt
      601 catacttgct ttttggatga tttctatcta ttagaagaga aggaatattt attcctgcat
      661 tattgactag accatcgatc gtcttgaaat gtttcattac tttatatatc ccttcttcta
      721 tgtccgtttt agaagacaca tcgactttta aagatagtag gttttcatgc tgtatacggc
      781 attcagttac atcaaaattc gctacttgtg cattctgctt caacaaattt tcgacgatac
      841 ttcttccaat tcctgaggaa cctccagtta caattactac ttttcctgca atatccaacc
      901 aatccgacat atgtgatcct ctccttcttt tttcttacaa atccagtata aaagctcact
      961 aaaaaaaatt aagacatgaa atttacagct tcagctaaaa aatgtgtact aatggaagag
     1021 caaaaaaaat tttcatcttt ttgcatagat tgctaaaatt cctgagcgtt atataagcaa
     1081 tgtttctctt tttgatatat aattgtttta tcatttaaga aaggagaatt ctaatgaaaa
     1141 ctttagatgc tattgcatta actttattga ttgtgggagg gttgaactgg ctgttggtag
     1201 gcttgttcga acttgattta gtagctatga ttgctggtgg ttcaacaact atttttgcga
     1261 agatcattta tatcgtcgta ggtatttgtg cgatctactg cttgaaattt ttcccaatga
     1321 ttactagaaa agttgatgaa agatattaga aagctataat tattaaaaaa gttattatct
     1381 tcatgaacct tccctttatt gggaaggttt tttcatttta aaccatctgc ttttctttgt
     1441 ttaagtgata tactgaataa agataatcta ttttaggagg agctatcatg cataaaggga
     1501 tttacgcagg cttgttggga actgtaatac ttttttctgc ctgtggatat aaaacaaaga
     1561 attctgttaa agaatcttca gcagccattt caacaactga ggttggttca actaaaagta
     1621 cttctactac ttccattact aatacttcta ctggtaatgt agattcgcaa catagccaat
     1681 caagtattca gtcgtttagc atttcttcaa catctgaaat gcaagaaagc actgtacctt
     1741 ctcttccatt agaaaactct gacaaagcac ttctatttct tattgcccac cgttccgaat
     1801 tacaaagtga cgatattgtt attagctttt atcaaaaaat tgatcgagat tatttgttca
     1861 cagcttccag caaacaaatc cgttcccaag gaggatctgg aagcgttggt ttttatcgag
     1921 tgtcacccga aggatcgatt acgatgacag atgcaaatgg aacaccattt tgattagatg
     1981 atattatacg gatttacagt actagcaagt cattattggt atcatttttt ctgagaaagt
     2041 tatacggagt ataaataagc atttgcatta acctaataat tcgttacagc tatttctctt
     2101 atgaatatac tcacttctct acttgctctc ttgataaatt tttggtatct acttcatttt
     2161 cggtcaactg agttaatgaa atttattgtc gggcggtttt ctagattcaa tttttctata
     2221 tttggataga agaatttact tttttacctt ttgacatatt ttcttcttat tattttaatg
     2281 atcccttttt caaattagaa agatagcctt tgtatcgtat tagatgaaat attcacaaag
     2341 ctaaccatta tacttgcatt tt
//
LOCUS       DADGHT010000185         2340 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.192, whole genome shotgun sequence.
ACCESSION   DADGHT010000185 DADGHT010000000
VERSION     DADGHT010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.192"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(365..1657)
                     /locus_tag="JX887_002813"
     CDS             complement(365..1657)
                     /locus_tag="JX887_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAX1258734.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1931..2191)
                     /locus_tag="JX887_002814"
     CDS             complement(1931..2191)
                     /locus_tag="JX887_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258735.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          781 a          441 c          355 g          763 t
ORIGIN      
        1 tatgggctac tctgtgatac ttattagcca ttaaactatt ttacccacat agcatatatt
       61 ttgaaatcgt tcattccgta aattcaacta aatatgccta aaaaaataaa aaatctaaga
      121 tagaataaga tttattcagt cttagatgga tttatagcaa ctttttcgta acaactttaa
      181 aaaatacgaa aagaaagagc tgttttactc tgactacgtt gctaaattgt cgtttaatca
      241 ttcatttaaa ccaaatcttt ttttatagaa ttcgttttaa tcctcctgaa tccaaaaact
      301 atgaaaaccg taattaaata gttaagagtt tttaaccacc ataattctct cggctatttt
      361 gaaatcagat aaattttgat cggacacata gttgaataaa cctaccgttg ttacggaagg
      421 taaatcgcat acttttcatt ctagaggaga aggtctcgtt gatcattaac tgattaagca
      481 ccatagccca gttttgaatt cgaccacctg accacttcgc gtgtaattct ttcgtgcgta
      541 aataaagtag ttttaggagt gcattctcat tagagaacgc tccttttttt gtgacttttc
      601 tgaagctgga gtggacactt tcaaccgcat tggtagtgta cataattttt cgaatggcac
      661 taccataatc aaatagttgt tcaacatgtg caaagttccg tttccagaca tctacagcac
      721 cagaataatg agaccaccga ttttgaaaac tgtcaaaagc agcatgtgca gcgtttagag
      781 aagaagcacc gtagaacttt ttcatatctc ggcagacttc cttatagtcc ttacttggaa
      841 tatagcgcaa tgcatttcga acaagatgaa caatacagcg ctgaacaatt accgatggaa
      901 agatcgcttt tgcgccttct tcgaggccag aaacaccgtc catcgaaatg aaaaagacat
      961 cttcgacacc acgtgctttc agttcatcaa atacttgcat ccagcgattt ttagattctg
     1021 tttgatttaa ccataatcct aaaatctcct tatttccttt gagatcatag ccaagaatgg
     1081 tgtatacagc atattctttg gcttcataat tttctcgtaa agtaacatac atacaatcaa
     1141 cgaatagaaa ggcataacac tttgctaggg ggcgggcttg ccattcttcc aattcaggaa
     1201 ggacagcgtc agtgatatct gaaatcattt catgggaaat atcaaagcca taaatagctt
     1261 cgacggttgc ggcaatatct cgttgactca ttcctcgtgc atacatggaa agaaccttcc
     1321 cttcgatgtc ggagacatct cgttttctct taggaattaa ctctggttca aaggaagctt
     1381 cccggtctct aggaacatca atagctactt caccaaaact ggttttaagc gttttagttc
     1441 catagccatt tcgacggtta tcgtgttcct taggctcttt agaatgggca tcataaccta
     1501 aatgattatt caattctcct tgaagcattt tttcaaaaag gggcccaaac acatctttca
     1561 aagcatcttg catgtcatcg acagattcag gttgataggc attcagaatg gattcagcta
     1621 acttttcggc atcaggattt cttttctttc tagccatcgt gtaatcacct cttgatctta
     1681 ttgtagaaaa agaaaaaccg cgaagcaacc acctgcctag gattaatggt tacttacacg
     1741 gtttatatta cactctcatc attaaaaaag tatctttcga tattactaaa caatgaaatt
     1801 atctatttga aatttaaatc tgataatata ttgagtgttc caatgagggc tttgatccta
     1861 ttatccatat ctttttcagt tttaatattg atacacatta taagaaaaag aaacttttgg
     1921 ttaatttatt tcatcccagt gcaaaatata aaaaagtaaa atagaccata ggcaatagat
     1981 taacaattaa tataatacaa gcaaatattc tattcattgt atttctgctt tcaaaaagtt
     2041 ctaatattga aagtataatt ccacaaatgc ctataataag tatgggaata agattagaaa
     2101 ataacacccc gagccaatct gtgaaaatta ctatatttac taatatccct attaacatac
     2161 ctatcatatt tattaaatca atttttttca ttagatattt ctcctttatt aaatctgaag
     2221 tacttatatt aaaataattc taaactattt acctcaaaaa gtgcaataaa ttatttctga
     2281 acaataaaat gatagtcaaa acaaaaaaat attgttaatc gttcagagcc atccgagagt
//
LOCUS       DADGHT010000186         2293 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.193, whole genome shotgun sequence.
ACCESSION   DADGHT010000186 DADGHT010000000
VERSION     DADGHT010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.193"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(51..1598)
                     /locus_tag="JX887_002815"
     CDS             complement(51..1598)
                     /locus_tag="JX887_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAX1258736.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
     gene            complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="JX887_002816"
     CDS             complement(1700..2053)
                     /gene="tnpB"
                     /locus_tag="JX887_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAX1258737.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(2043..2237)
                     /locus_tag="JX887_002817"
     CDS             complement(2043..2237)
                     /locus_tag="JX887_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258738.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          644 a          477 c          408 g          764 t
ORIGIN      
        1 tacgtcaaat aacccgacct atagaataga atcgggaatg tttggcgttt ttagttacga
       61 gaaaaatgtt gttgtacatc cttgttccaa ggcaacagtt gatctaaagt ttctgctgaa
      121 agtacgggaa gatttggtat cttatcaaat agaaactcta gatactttac aggattcaat
      181 ccgttaagtt ctgctgtttt atatacactc agaatgattc ctgaagttcg tgctccttca
      241 agacttgtgg aatgcaacca atttttccgt cctatcacca gctctttgat atttcgctcc
      301 gcacgattat ttgtgagttc taaacgacca tcttcaaaaa taggttcaaa accacttcgt
      361 agtttacacg catattgaac ggctgcatcc aacttggatt ttgcaacagg atctatcgtt
      421 gccatccact cataaaaagc aataaataat ggacgcagtt cttgttgccg acagcttaat
      481 cgcttctcag gagaaaagtc tttccatttc ttttctagga caaaccattt atccaattgt
      541 ttgactgctt gagctgcggg aatatccgtg tttttctttc cttttggaat tgcttcgaaa
      601 aatttccgcc gaacatgcgc gaaacaatag acaagtcgta cactttccac ggcattatac
      661 ccgctatagc cgtcacagtg taaataccct gtaaactcct tgagaaaagt tttcggaaca
      721 tctccagcac gactttcgtc gtggtgataa taaacgatgg gatgctgact gtcttttcct
      781 gtacaaaact gccagtaata ggtatctgtt ttggcacttt caatcacacg ataacttgtt
      841 tcatccccgt gtagaatctc ttcttgatta agatagactc ttaatcgttc tcctaaaggg
      901 tctaacgcgt tttgcactgc tttaatatgc caattggtga tattatctct cgaaatatcc
      961 aacccatgtg tttgtttcca atagttctct tgccgatagg caggaacttt ctgaccaaat
     1021 ttcatccgga tcgtttccgc cactaaacta ttggaaccta agctattaga aatcaaaggt
     1081 ttaggaacga tcgctttttt aaaagaagaa agtccttctt tttcgcagct tttacaacaa
     1141 taggtatgtt gataatgggt gagacaatcc aacatagcct gatggaaacg aatttcttct
     1201 cgtacttttg tccgtccgat atctttcatc tgtgaaccgc aatgttcaca aaattgttct
     1261 tccaaaggaa ggagatgttc tttctctgtt ataggtaagt gtttgatttt gtctgctttc
     1321 gttcctacaa ctcgttgatg tccttttact ggaataatgg tggcagctgc ttctggaaca
     1381 cttacagaaa tttcttcatc actaaaaaga ttcaattgcc cattcgtttc ctcaaagaga
     1441 gtctctttag agcgtccaaa taatttgttg gttaaataat tgaccttttc attcaatagt
     1501 tggatttcag ttgtaagatt ctgaatggtt tgttgttgtg cttgattggt tttatgggct
     1561 tcttgaagca actgaagcaa cgtatctgta gtttccaaaa tttttcacca ccttgaatcg
     1621 aactgatttt gttacagaat accacaagaa acgcacaaga aataggggtt caacacattt
     1681 tttgtgttaa ccccccagct taaaaaactc ctttttttcc tggcaaaata gctcgaggtt
     1741 gatcgatact taatccttct aacaaccatc gaacctgttg gttcgttaag gttcgaactt
     1801 cgtctttcgt ccgaggccat tttaacttgc cgttttctat ccgcttataa cagagaagaa
     1861 aaccatcacc gtcccaatag agaagtttga aacggtcttg acggttcccg caaaataaaa
     1921 aaacggcatc ttcgtaaagc tcgagttgat actcttgttg aataagactg gcaagaccat
     1981 caattccttt tcgcaaatct gtttttccgc acacaatata aatatgtttg gtttgaagta
     2041 aatcataaag cattggacaa cagttctttc aaaatagctt gaagaatata attgttaata
     2101 ccgttataga tcaaaacttc agaaccattc tctcttttga tgcgcatcgc taacttggca
     2161 gccgcgggtt tacctttttc tggtgcactc ttttcgtttc ctaattggac aggaacaatc
     2221 tcatttaatt tatacataga aaacctccag acttcttgat agctcaagta tatcttgagg
     2281 tgcatttgtt agt
//
LOCUS       DADGHT010000187         2256 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.195, whole genome shotgun sequence.
ACCESSION   DADGHT010000187 DADGHT010000000
VERSION     DADGHT010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.195"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(151..2148)
                     /locus_tag="JX887_002818"
     CDS             complement(151..2148)
                     /locus_tag="JX887_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAX1258739.1"
                     /translation="MIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKA
                     LVTNKANQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHL
                     KEATKRLSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVY
                     IKNSGVTDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADE
                     AEKYLAKGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGS
                     NLMLSMNAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHE
                     QGSKEITENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKS
                     SVFNRSGQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRD
                     SFKEFGLGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYT
                     PIQLAQYASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMA
                     ILREGFHQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGP
                     TDNPEIAISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          574 a          504 c          411 g          767 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct tatttt
//
LOCUS       DADGHT010000188         2247 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.196, whole genome shotgun sequence.
ACCESSION   DADGHT010000188 DADGHT010000000
VERSION     DADGHT010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.196"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..176
                     /locus_tag="JX887_002819"
     CDS             <1..176
                     /locus_tag="JX887_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAX1258740.1"
                     /translation="TEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQN
                     IVLATHPKYFKNI"
     gene            complement(901..1236)
                     /locus_tag="JX887_002820"
                     /pseudo
     CDS             complement(901..1236)
                     /locus_tag="JX887_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1333..1785)
                     /locus_tag="JX887_002821"
     CDS             complement(1333..1785)
                     /locus_tag="JX887_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258741.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(1792..>2247)
                     /locus_tag="JX887_002822"
     CDS             complement(1792..>2247)
                     /locus_tag="JX887_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAX1258742.1"
                     /translation="EKVNTVDLEIKNKLVDELTFYFDTVGFLDEHGVYHIKDFGAIRE
                     RISQDNEQGRAARVFYEHIIVPRMEKVDWKRYAGCVAINSLPGGGVAWAIGTQGDFIE
                     ALKAFNFEKAADLLLKIAEKQLGKAAAKELAKVNIVAGIAAAAASCALE"
BASE COUNT          788 a          397 c          246 g          816 t
ORIGIN      
        1 aaacggaagg attaaagtgg gaaaaaatta tggaacaaca ttatcaacta tttgaggcat
       61 taacaaaaca agatccagaa gaagctaact ttctaacatc gttgcatctt catttaatgc
      121 ttaatgagca aaatattgtt ttagctactc atccaaaata tttcaaaaat atataacttt
      181 taactctttt taaattaaat ggttgttctg atcagaaaaa tatcgcttgt tttcttatta
      241 tgtaatatat ttcataaact attctgcata acaactattg tttgtacttt ttacattgga
      301 taactaatta tgactgctga taacttttga tattaaacta gtatctccaa tacaaataaa
      361 aaatagatat cttgttcatc aaaattagtt cgtggatact taccttcatt tacatcattc
      421 agcggtttcc cattttcttt tattctatta tttcattttc taatagactt ggcttcattt
      481 cgcaatactt tttttcaata ggcatcaaat tggtgttgtt tagatattta gttgtagttt
      541 tgtgacatga taagtatgct cctttttctc ttttccacta atacaacgat caaagggtgc
      601 ttttttcaaa aaactagaaa aatcaaaata agattcgtat tttgattcta tatatcctgt
      661 ttcaactaca tcttatattt cacaatagaa taaatagcct tttgcatagc tgcttaactt
      721 ataagaaatt gcaatttact tcttcaaagt gaaaacgaat atgagtaaaa taaaattatt
      781 cttcttacag ataattaaaa atagcgcgta acaaaaatcg gcattcaatc acataattag
      841 gattgatgcc gattacttat attctacgta tagttttagt attcttattt tttatcacca
      901 gtaaccaatt gagaacagcc ctaaagcaga atagtctttt atctcaaaac gcttaatttc
      961 aggcttagga atatgaataa tcttttgagt atattctttc tcttttaatc ttactgaaga
     1021 aataccactg cctatctttt ttacaaatat ttcatttggt gtacagacta ataaaacaat
     1081 atttgtaatc aatccttgca ctaaagaatt aaaaggaaga ctatttaaaa cagggtgtgc
     1141 ataactataa catgtgaagt agttattttg aactttaact tttaaaaact ttaaaaataa
     1201 tcttatttgt tcttctaaac aatcatctat actcatataa tcactccact aattaatctc
     1261 cccaaaaaga cacagcatta agagatatac caacacaaca gtgcaaataa ctctacatct
     1321 tccttcgcaa ccttatttca ataaaccata aaaattattt tttaatagaa actgaaaatt
     1381 aaaactagaa aaagtagttt taccgaatgt aagagcatca tcaccatcaa tatagaaata
     1441 cattcttttc cagttacatt taatttttaa acaaaattct ccccaaaaag gaactttttc
     1501 tagtgaaaac ttggtaatct ctttgtaatt aattcttgtt aaagaataat taaacacttc
     1561 atttttactt gttatttttt cattgactat aactagttca tctggtaaaa aaattaacca
     1621 acaaacatcg acaaacagta aatgatataa tccatttcca cctccaagca tattcaatac
     1681 tggtgaacat gccttagaaa cacgaatata gttatggttt aaatagatat tttctttaaa
     1741 cattgcttgt ttaaaagcca tatgctcttg ttctaaactt ttcataaact tttactctaa
     1801 tgcacagcta gcagcagctg ctgcaattcc tgctacaata tttaccttag ctaactcttt
     1861 agctgcagct tttcctaatt gtttttctgc aatttttaat aataaatccg cagctttttc
     1921 aaaattaaaa gcttttaatg cttcaataaa atctccctgc gtacctatag cccaagccac
     1981 tcctcctcca ggaagagaat taatggctac acatccagca tatcgtttcc aatcaacttt
     2041 ctccattcta ggaacaataa tatgttcata aaagactctt gctgctcttc cttgttcgtt
     2101 atcttgactg attcgttcac gaatagcacc aaaatccttt atatggtata caccatgttc
     2161 gtctaaaaaa ccaactgtat caaaataaaa agttaattca tctactaatt tattctttat
     2221 ttctaaatca actgtattca ctttttc
//
LOCUS       DADGHT010000189         2193 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.197, whole genome shotgun sequence.
ACCESSION   DADGHT010000189 DADGHT010000000
VERSION     DADGHT010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.197"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..131
                     /locus_tag="JX887_002823"
     CDS             <1..131
                     /locus_tag="JX887_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAX1258743.1"
                     /translation="KSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            104..781
                     /locus_tag="JX887_002824"
     CDS             104..781
                     /locus_tag="JX887_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAX1258744.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            771..1913
                     /locus_tag="JX887_002825"
     CDS             771..1913
                     /locus_tag="JX887_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAX1258745.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            1926..>2193
                     /locus_tag="JX887_002826"
     CDS             1926..>2193
                     /locus_tag="JX887_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1258746.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIF"
BASE COUNT          796 a          284 c          447 g          666 t
ORIGIN      
        1 taaaaagctt gaaaaatgtt aagaacatct acggtgacgg caacagttct agaagaataa
       61 caaaaacatt gaatcaaata ttgaatgatg gggaagatat taagtggatt caaaaacaaa
      121 tagcttatta aaatatacta gtgatccata cattattatt ggggctggcg gacacgcaaa
      181 agtcattatt gaaaccttaa gattagaaaa taagttaata tatggatttt ttgatgataa
      241 gcaaaataaa atgcaagatc tgaaatatct tgggaaaata aacgaattga atagctgggc
      301 ggatagcaaa aaaaaaatct ataaatttat tgtagctatt ggtgactgtg tagtaagaaa
      361 aaagattata aaaaaattga atatgccaag tgagcaatat ggaatagctg ttcatccaag
      421 tgctatagtg gcaaaagaaa tttcaattgg ttatggaact gttatttttg cgaatgctgt
      481 aattaaccca gatgctgtaa ttggagagca tgctataata aacacaggta gcattgttga
      541 gcatgattgt agaattaata actatgttca tttatctcca ggtgtatgct tagcgggtgg
      601 agtacatgta ggtgtaggaa ctcaaatagg aattggttct caatgtatcc agatgaagaa
      661 aattggatct tggtgtatga taggcgcagg gagcactatt gttaaggata ttccctcaca
      721 ttccttagct tatggcaatc cagctaaaat taagaaagaa ggaattaatt ttgaattcta
      781 gaattttatt atcaagtcct catatgggag gaacagaaga aaaatatgtt gctaaggctt
      841 ttaaagataa ttggatagcg ccattaggtg aaaatgtgga taaatttgaa gaaagtatta
      901 caaaatatac tggttctaag ggcggagctt ctgcgttaag ttcaggtaca gctgccatac
      961 atcttgcctt aagactgctt aatgttggaa aaaacgatat tgtctttgct ccttcattta
     1021 cttttatagc tacagtaaat cctattttat atcaaggggc tgtaccagtg ttcattgact
     1081 cagaacctaa tacatggaat atgagccctg ttgcactaga gagcgcatta gaagaagctg
     1141 aaagaaacaa ccaattacct aaggcaatca tcgtagtgaa tttatatggt caaatggctg
     1201 attatgaacg aattttagct attgcaaacc aatttaatgt tccagtgata gaagatgcag
     1261 cggaatcgtt aggttctact tataagggaa tttcgtcagg cttatttggg acaattggga
     1321 tctattcatt taacggtaat aagatcatca caacctcagg tggaggagct ctagtgtcta
     1381 gtgataaaaa atatgttgag cattcaagat ttttagcaac acaagcaaga gatcaagcac
     1441 cgtattatca acatagcgaa ataggttata attaccgtct aagcaatatt tctgccggta
     1501 tcggacgtgg acaaatggaa gtattgaatg atagagtagc taaacgaaga gaaattttca
     1561 atcgatataa ggaagctttt tctggaattg atagaattga aatgatgcca gaagtggatg
     1621 gcatggtgcc aaatcgttgg ttgtctactt taacgatcaa tgattataat tctattgatc
     1681 aagtagttaa cgtaataaat aaactaaatg aaaaaaacat tgaaacaaga gctttgtgga
     1741 aaccactaca tttgcaacca gtatttcaag gggtaaaaat gtattaccat gataataatc
     1801 ttagtgtgtc agaaaagtta tttaatagcg gcttatgctt accttctgga agtaatatga
     1861 cagatagtga acaagaattt gttattgatg agtttaaaaa aatattcaag taggtgtgat
     1921 attttatgaa cataggaatt attggtttag gttccatggg gaaaagaaga cttagactca
     1981 ttcaagaaca ctttaatgat attttactat gtggtgttga tactaatgag gcgagacgaa
     2041 aggaagttga aaaggaattt ggaataccaa cttataatag tctaacagag gcaaaaaatt
     2101 tgtttgaaat aaattcagtt tttgtttgta catcccctat aacccatgaa tttattataa
     2161 aagaggcttt aaatttagat tgtaatatct tta
//
LOCUS       DADGHT010000190         2104 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.198, whole genome shotgun sequence.
ACCESSION   DADGHT010000190 DADGHT010000000
VERSION     DADGHT010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2104
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.198"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..407)
                     /locus_tag="JX887_002827"
     CDS             complement(<1..407)
                     /locus_tag="JX887_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HAX1258747.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFSRGNDEQSLE
                     ILTTIFTEKKINTIIFACGSITATSQVAYEQAKT"
     gene            complement(581..880)
                     /locus_tag="JX887_002828"
     CDS             complement(581..880)
                     /locus_tag="JX887_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HAX1258748.1"
                     /translation="MLETAIEVLEKCAQLVTTPEEWGYESVTMEKEEIEMGTLPKNVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVCGLLVEGRLVWSQIGGTNE"
     gene            complement(907..1215)
                     /locus_tag="JX887_002829"
     CDS             complement(907..1215)
                     /locus_tag="JX887_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAX1258749.1"
                     /translation="MFQNKGQRYVTKGVMDSLLVELQTLCWNLIDQNVQKKLPLDYLQ
                     IFEFSIEKGNQKLVHRQEEPEARKEYLISPKLRLESVSQKIWVIDSGEYQTMLLPEEY
                     "
     gene            1545..>2104
                     /locus_tag="JX887_002830"
     CDS             1545..>2104
                     /locus_tag="JX887_002830"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258750.1"
                     /translation="MKALTISFMEDVFHSLDLEHLNKLAKVLPQKLSGSSIIPKNPSD
                     SFKNRLFNQFLKEKNLRYIFKYISSGYFHDIVANDENIYKSTSIQSIEGFFEEIKNKE
                     LESPFSFYIYLIEQTDEDNIVDFFQNIDGLRTFKNNSLIYIQNKKKNKGCTDISLEYK
                     KMEDLLTLYKKDKIDAENREKVLLKE"
BASE COUNT          693 a          365 c          292 g          754 t
ORIGIN      
        1 gtctttgctt gttcataagc cacttgactc gttgccgtaa tcgaaccaca agcaaaaata
       61 atagtgttga ttttcttttc tgtaaaaatg gtcgttaata tttccaaaga ttgttcatca
      121 ttgccacgag aaaatacccg aggacttttc gcttttgtat acgaaaaaag attcacggca
      181 ataaaaccag taaatcccaa ttgtcggata ttcttttcga ttaataacat actcaaatca
      241 ttcgtaaatg gttctgtatc tgttggacga atagtaatga ctactgctaa tttatcttcc
      301 gcttcttttc ctttgatcgc ccattgtcgt ttgaaaacat agcgatgggt atgatgagga
      361 tctcgccaaa cttctgtttg tgtggtcact aattcttttt caatcatctc tttttctcct
      421 atgctaattt ttgttcaagc aattcaatta ccattgccgt tataagtgtc aatactagtt
      481 gaaaatattt catattcttt ctcctttttt cttcagaatt cgataaatcg cggtaaggat
      541 atcttctaaa catttcgcaa tcattctcaa ataatcgatc ttattcattc gttcctccaa
      601 tctgactcca aaccaatcgt ccttctacca gtaacccaca aacaaattct cgctggctgg
      661 taatatctgt aatgaaataa actacatagt cttttccatc ttctggtgcg caataaatat
      721 aaagatgtgt catcactaaa cgtggtagat gaacattttt aggaagcgta cccatttcaa
      781 tttcctcttt ttccatcgta acggattcat agccccactc ttcaggagta gtgactagct
      841 gtgcacactt ttccagtact tcgatagccg tttctaacaa gtcatttcgc tcctttcttt
      901 tagatatcag tattcttctg gtaataacat cgtttgatac tcacccgaat caatgaccca
      961 tattttttga gacactgatt ccaaacgaag cttaggtgaa atcagatact cttttcttgc
     1021 ttccggttct tcttgacgat gaaccaactt ttgatttcct ttttctatcg aaaattcaaa
     1081 gatttgaaga tagtctaaag gaagcttctt ttgaacgttt tgatcgatta aattccaaca
     1141 taaagtttgt aattccacca gtaaactgtc cattactccc tttgtgacat aacgttgtcc
     1201 tttattttga aacatttctt ttccctcctt tgtcgtaaaa aatagcccaa tcttctataa
     1261 agaagattgg acttcatgga tataatatat atttgaattt atctctattt cattgctata
     1321 ttatttattt caattaactg aatagacatc acaactaaat ataagaaatg cttttctaaa
     1381 agtatggagt tttcatattt agtacctcta tactaaattg cgactacaag tttaaaattt
     1441 atatagttat tagtaactaa gatacttaat tttgcttaat gaactatcct attaatgtta
     1501 tactactatt gttattataa ataatacaag aaaggaagtc aaaattgaaa gctttaacta
     1561 taagttttat ggaagatgtt tttcattctc ttgatttgga acatcttaat aaattagcga
     1621 aagtacttcc acagaagtta agtggctcat ctattattcc taaaaaccca tctgattctt
     1681 ttaaaaacag gttatttaac caatttctta aagaaaaaaa tttaagatat atatttaaat
     1741 atattagtag tgggtacttc cacgatatcg tcgcaaacga tgaaaatatt tataaaagta
     1801 cttctattca gagcatagaa ggattttttg aggaaattaa aaataaagag ttggaatccc
     1861 ccttttcatt ttatatctat ttgattgaac aaacagatga agacaacatt gtagattttt
     1921 ttcaaaatat tgatgggtta agaacattta agaataattc tttgatatat atacaaaata
     1981 aaaaaaagaa taagggttgc actgatatct cacttgaata taaaaagatg gaagatttat
     2041 taacccttta taaaaaagac aaaattgatg ctgaaaatag ggaaaaagta ttgctaaaag
     2101 aaaa
//
LOCUS       DADGHT010000191         2021 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.199, whole genome shotgun sequence.
ACCESSION   DADGHT010000191 DADGHT010000000
VERSION     DADGHT010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.199"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..153
                     /locus_tag="JX887_002831"
     CDS             <1..153
                     /locus_tag="JX887_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1258751.1"
                     /translation="KQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVKMPGLMA
                     ALKRVY"
     gene            172..1257
                     /locus_tag="JX887_002832"
     CDS             172..1257
                     /locus_tag="JX887_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAX1258752.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            1290..>2021
                     /locus_tag="JX887_002833"
     CDS             1290..>2021
                     /locus_tag="JX887_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAX1258753.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGP"
BASE COUNT          773 a          232 c          359 g          657 t
ORIGIN      
        1 aagcaaattg ctaagacgga ttcttcagca aaaaaaataa caaagttgct ttacaatatg
       61 ccagctccac tatttttatc tgctgtaaaa gttggaagct tcgttgaagt gaaaatgcca
      121 gggttaatgg ctgctttgaa gcgagtatat tagttaatgg aggaaaatat aatgaaaaga
      181 attttgcatt ttcagggacg aatgggttta ggtggagcag agtctttcat gatgaattta
      241 tatcgtaaaa ttgatcgtac aaactatcaa tttgattttt tgatttatga agattatgca
      301 gatgttcaag actatcattc agagattgaa agattaggag gccgtatttt tgttgtacct
      361 aatcctaaga aaaatatttt taaatattta atagaagtga ataagttact aaaaaaagaa
      421 tctttttcta tagttcacaa tcaggtttat tttggcgggg gaattaattt atggttagcc
      481 aaaaagaatg gaatcagaca gagaattgct catagccatg caactgaaga tggaaaatct
      541 caaaatattg taatgaatgt attgcgtaaa tttttaacca aattgttgtt acaaaatgca
      601 acagactacc ttgccgttag tcaagaagct ggtgaaagtc tgtttcaaaa ccaccccttt
      661 gagatagttc ataatggtat tgatttagag ctttatagta aaaattcaga agctaaggtt
      721 aataagagaa aagaattgga tatctcaatg agtacttttg ttgtgggaaa cattggacga
      781 ttagagaaac aaaaaaatca atcttatttg ttagagattt ttttagaaat actaaaaatg
      841 aattctgatt cttacttgat tttagtaggt gaagggtcac ttagaaataa actgaaagcc
      901 aaagcagtag aattggatat agagaaaaga gtaaaatttt taggagaaag aaacgatatt
      961 cccgagttat tatctgtgat ggatgttttt gtaatgcctt ctctttatga aggtctgcca
     1021 atggttggat tagaagcaca agcagcaaaa ttaaaattag tcttagcaga tactatttcc
     1081 aaagatacaa agttaacaaa taatgtggat tttgtatcat tagatgaaac accacaagaa
     1141 tgggcaaaaa aagtaataaa agagccgtat gctaataaaa taacacaaga actaaagagt
     1201 tatgatgttt cgtacactac tgaacaaatg gagagtatat atagtagaga tcattaaaaa
     1261 tgttcaagat attttaggag tgattatttt tgaaaatatg ttatttgata ttggcataca
     1321 atgatattgg caacttaaag agattggtca atcgattgaa cgaaaatgca gtttttatta
     1381 ttcatataga taaaaaaact gatatagaac catttattga agcatttaaa tcatatgata
     1441 atgttgaatt tttatgtaat aaaaaccgtg ttaaaattta ttggggtggt ttttccattg
     1501 tacaagcaga aatcaattta gtaaagagag cattacaaaa tgagaaatat ttaaaatatg
     1561 tattattatc tggtgctgat tatccaatca aagataatga gtatatttat aattatttta
     1621 aaaagaatag ttcagtggag tttattcgtg gaatagatct agatcaaatt aaacataaag
     1681 aattttatta taaacatata gatgtatatc aaaaacatga ttatcctaga attaatagga
     1741 ataacacaac tgcatttaaa atttttagag ctataattaa tcgttgtctg aggatgatta
     1801 aacttccccc aaaaattaga caccataaat ttgatttgta tcatggttct caatggtggg
     1861 ctttgtcgaa agaatgccta acagaattaa tacaaatgta tgaacaaaat caacaagact
     1921 acctgaattt taaaataggt atgtttgccc cagatgaaaa attttttcat acactttttt
     1981 ttaattcctc gttcaaaaat aaaaatgtta ttggaggacc a
//
LOCUS       DADGHT010000192         2006 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.200, whole genome shotgun sequence.
ACCESSION   DADGHT010000192 DADGHT010000000
VERSION     DADGHT010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.200"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(129..416)
                     /locus_tag="JX887_002834"
     CDS             complement(129..416)
                     /locus_tag="JX887_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258754.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            complement(587..1939)
                     /locus_tag="JX887_002835"
     CDS             complement(587..1939)
                     /locus_tag="JX887_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAX1258755.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
BASE COUNT          548 a          403 c          347 g          708 t
ORIGIN      
        1 aaaaaggggt tgacaaagct tgtcataacc cctttttctg attaaaagat agtaaagaga
       61 cagtcatcgg taattgtgat gattttttgt catcacttaa ggatgagcgg ccttttcaaa
      121 aactgtcttt aaagatcatc atcagtttct agcacatatg gctgaccttc atatgtgtac
      181 tctgtattca atgtgccgtc attttcatct gagtagatgc gtctactgaa aggaaaacga
      241 tgagaaacat tatctttggc gtcatttgct ggcatcgtgt aatattcctc ttgcgtttca
      301 ttcaactgag agagtacttg atctgccaac tcatcaatat tgatcgttaa tttcttcgaa
      361 gcacttttat aatcttctaa aaatgcatct tgttggacaa aatattcttt attcatcttc
      421 tttctcacct ttcttttcaa aatcaaataa agctgcttgt tcttttatgt aacagcttta
      481 tctttgctgc ttattgtgac aaaaaattcg aagaaagaca actaattgta cttttcacaa
      541 aaaaagacag agggtcgtga caaaattgtg tcacaaccct ttttctttat tgtgcagttt
      601 cgatttcgcc tagcgctgct tgtgcaagta ggttcaagta attccatggg cggtcaaaat
      661 gtggttggaa gaagaaatct gaaagtgcga gatcttctac agtcatttta ttttgaacag
      721 ctaaagacat ggtatttgct gattgtgtaa tgtcgtattt ggacatgaac tgagcaccta
      781 cgatacgatt cgttcctttt tcatagacta gctccatcat tactttttca gtagttggca
      841 tgaactctgg acgataatta tcttcaaata cagtcgcttg gacttctaga tcgttcaaag
      901 ttgcgctttc tttggtcaca cctgtcgaac cgatcgtcca gccaaatagg taaagtcctg
      961 aagttccttg agtaccacga tacgccattt tatgatctgt caagttattt cccacaagca
     1021 aaccttgacg aacggcattt gttgccaaag gaatatagtt ttgcgtgcca cttggattgt
     1081 agttgactac tgcagagtct ccagctgcaa aaatgtctgg attacttgtc tgcatgtatt
     1141 cattcacttt gattgccccg tttggcagtg tatctacttt tccttcgatc agttttgtat
     1201 ttggacggaa gcccacacat aaaatgacca tatctgtatc aaatgtatct gttggtgtag
     1261 ctacttgttt cacttttcct tcttcatctg tgataaattc agtaacattt tcgcctagcg
     1321 caagagtaac accgcggtct gtcaattctt tttctaagat atctgtgaat ggtttatcta
     1381 gatatttatt caagatgcga tctaatccat caatcaatgt cacttgtttt ccagattcga
     1441 caaaagcttc tactaattca ataccgatat atccaccacc aacaattact acacgttttg
     1501 cttctttcgc ttgtgcaata atttcatttg cttgattgta gtttttgcat aggagtacat
     1561 ttttcgcatc gattccacta atcggtggga taataggcca tgaaccagtt gtcatcacta
     1621 atttatcata agaaaccgtt tctgtttctc ctgttttcag atcttttgcc gttactgttt
     1681 tattttctgt atcgacgtct gttacatcgt gttccatttt aactgttgct cctaatgaag
     1741 ataattcttc aggatttgag tagaacaagc ctgctgggtc ctttactact ccgccgacat
     1801 aaagtgcgat accgcaagat aagaaagaaa tattgtcatt tctttcatat actgtcactt
     1861 ctgcttctgg atgatttttt aaaatacttt ttacagctgc agtacctgca tgagtacagc
     1921 caattactac tactttcatt tatggtccct ccgattaaca ttttgtcctt cgacaaaact
     1981 actataacag aaataaaacg gataca
//
LOCUS       DADGHT010000193         1979 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.201, whole genome shotgun sequence.
ACCESSION   DADGHT010000193 DADGHT010000000
VERSION     DADGHT010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.201"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..367
                     /locus_tag="JX887_002836"
     CDS             <1..367
                     /locus_tag="JX887_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAX1258756.1"
                     /translation="KKQIVPKEIETWWRIEMQLRRGKATDWHAMVRESLDSFASPHYL
                     PGDVKPVDRIMIKGLNQDHSEWAYISRNLKYRLRKLLKEESQNDELTNHLRETFKESA
                     NDLKIELDTWLLGLDVTEK"
     gene            567..770
                     /locus_tag="JX887_002837"
     CDS             567..770
                     /locus_tag="JX887_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258757.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSAKEGFNLGFSISFKKGTKN
                     TSISHNNRELTDSQKINGLSGRK"
     gene            1330..>1979
                     /locus_tag="JX887_002838"
     CDS             1330..>1979
                     /locus_tag="JX887_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAX1258758.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVDDK
                     VHPLKLSWSIDRITIVGKLNDTIAYWTQNGVVFVDFEQLMRLNENQGYLKSVGTNGWQ
                     LFDQYGEDIAYIEMLKFHPDKGRIDFNPNKIGEFLKGSMKQFIHDLFLDAHFSRADIA
                     CDILGVPDDFITQYRIVDPVSFKPIYGRSGKLETAYWGSRASERQVRMYNKKLEQER"
BASE COUNT          657 a          305 c          461 g          556 t
ORIGIN      
        1 aaaaaaacag attgtaccaa aagaaatcga aacatggtgg cgtatagaaa tgcagctaag
       61 acgtggcaaa gcaacagatt ggcatgcgat ggttcgggaa agtttagata gctttgcaag
      121 tcctcattac ttgcctggag atgtaaaacc tgttgataga attatgataa aagggctgaa
      181 tcaagatcat tcagagtggg cgtatattag cagaaatttg aaatatagat tgcgcaaatt
      241 gttgaaagaa gaaagccaaa acgatgagtt gacgaatcat ttacgagaga cgtttaagga
      301 atctgcaaac gacttgaaaa tagaattaga cacgtggctt ttgggtttgg acgtgacaga
      361 gaagtgatac cgaataagaa aagtcagatg agtgagagta aatttacgtc aatgtttaat
      421 gacgtgagtt tacgataagc gattattttg cgtgaagcaa aataaagcgt aaaaggagtt
      481 gagagcgtga cacgctttcg gctccttttt tcgttgtcac ttgtgacagc gaataccctc
      541 ggagagcatt tggaattgtg acagccatgt cacaattagg aaaatgttac tctttgtcaa
      601 agagtaacag aaaggtttac actcttttta ttagcgacag cgcgaaggag gggtttaact
      661 tggggtttag tatttcgttc aaaaagggaa caaagaatac aagcatttct cataataatc
      721 gtgagttaac tgatagccaa aaaatcaatg gtttgtctgg tagaaaataa ttagcagatt
      781 tacaagtggg aaataaaaag ctgaaagaag aaaattgcat ttcaaactac attttctaca
      841 atagctctaa aatggcatat tttgcgttct gagcggtttt agcgtttatt tcgtttagtt
      901 atcggcacaa tcgttaaaac acgttagagg agcgaaaatg gagcctgtaa ggcgactggt
      961 agcggaacga tcgtgttaga ttgtgaaaac cgatagctga atgaaataaa cagcgggtgc
     1021 gccctttcca tttcggcagg aggaggctca aggggttcgg ggaatgaaat tccctgaggt
     1081 ctttttattt ttttaggagg agtgctataa tcaaagaaaa cgagaaaaaa gagcaaaata
     1141 aaagccgagc agtgcgctaa cactctcgac tatttacgga aactacttca cctagctccg
     1201 taactcaggt tcattatacg aatattttta ggtttcttca agctagagat ttttggatat
     1261 gaatttttag ggttacgtga actctggaaa ttctttccaa aagtctcttt tttcgtctgg
     1321 aggacgaaaa tggcaaatga aaatcagttg agtgaaattc aatcaaaaat tgaaggtcga
     1381 ggggcagaaa aaagaacaac gataaatcag ctcgaaaaac ttaaccgtat ttctaacagg
     1441 cggttaagtg ttgacgataa ggtacacccc ctaaaattaa gttggtcaat cgatcgaatt
     1501 acaatcgtcg gaaaactgaa tgataccata gcttattgga cgcaaaatgg agttgtgttt
     1561 gtcgattttg agcaattaat gcgtttgaat gaaaatcaag ggtatttgaa gtcggttggt
     1621 acaaatggtt ggcaattatt tgaccaatat ggagaagata tcgcctatat cgaaatgtta
     1681 aaatttcacc ctgacaaagg tcgtattgat tttaatccaa ataaaattgg cgagttttta
     1741 aaggggtcga tgaaacaatt cattcatgat ttgtttctgg atgcgcattt ctcacgtgca
     1801 gatattgctt gcgatattct cggtgttcct gatgatttta ttacccagta tcgaatcgtt
     1861 gaccctgtgt cttttaagcc aatttatggc cgttctggca aattagaaac agcgtactgg
     1921 ggtagtcgtg ccagcgagcg acaagtgcgg atgtacaaca aaaagcttga acaggaacg
//
LOCUS       DADGHT010000194         1972 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.202, whole genome shotgun sequence.
ACCESSION   DADGHT010000194 DADGHT010000000
VERSION     DADGHT010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1972
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.202"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1131)
                     /locus_tag="JX887_002839"
     CDS             complement(<1..1131)
                     /locus_tag="JX887_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAX1258759.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDD"
     gene            complement(1261..>1972)
                     /locus_tag="JX887_002840"
     CDS             complement(1261..>1972)
                     /locus_tag="JX887_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAX1258760.1"
                     /translation="YENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKD
                     LGKLDINWREYNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMN
                     ARKKEIAVLLSLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVT
                     GDIAKQIAKQSASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLII
                     SSFNILRRNPKELLIDNN"
BASE COUNT          623 a          382 c          313 g          654 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgcgcattc tcattagaga acactccctt
       61 ttttgtgact tttctgaagc tagagtgaat actttcaact gcattagtag tgtacatgat
      121 ttttctaatg gcgctgccat aatcaaagag ttgttcaaca tgagaaaagt ttcgtttgca
      181 tacatctact gcaccagaat aatgagacca ccgattttga aaactgtcga aggcagcgtg
      241 tgcagcgttt aaagaagaag cactgtagaa ttttttcatg tctcgacaga cttccttata
      301 atccttactt gggaggtatc gtaacgcatt tcgaacaaga tgaacaatac agcgctgcac
      361 aatgacagaa ggaaaaattg cttttgcgcc ttctttgaga ccggaaacac cgtccatcga
      421 aatgaaaaaa acatcttcta caccacgtac tttcagttca tcaaatactt gcatccagcg
      481 atttttagat tctgtttgat tgagccatag gcctaaaatc tccttgtttc ctttaagatc
      541 atagccaaga atggtgtaca cagcatattc tttagcttca tagttttcgc gtaaagtgac
      601 gtacatacaa tcaacgaata gaaatgcata acacttggct aatggccgag cttgccattc
      661 ttccaattca ggaaggacgg catccgtgat atcagaaatc atttcgtggg aaatatcaaa
      721 gccgtaaata tcttcaacgg ttgcggcgat atcgcattga ctcattcctc gtgcatacat
      781 ggaaagaacc ttaccttcga tgtcggagac atctcgtttt ctattaggaa tcaactcagg
      841 ttcaaaagaa gcctcccggt ctctgggaac atcaatgttt actttaccaa agctcgtttt
      901 aagcgtctta ttgccataac cgtttcgtcg attgtcatgt ttctttggct ctttagaatg
      961 ggcgtcatac cctaaatggt tattcaattc tccttgaagc attttttcaa ataagggacc
     1021 aaacacatct tttaaaacat cttgcatatc ctctacagat tcgggttgat aagtattcaa
     1081 aatggattca gctaacttct cagcatcagg atttcttttc tttctagcca tcgtgtaatc
     1141 acctcttgat cttattttag aaaaataaaa accgtgaagc aaccacccgc ctaggattga
     1201 tggttactta cacggtttat attacactct catttttggt gctaaaaagc accgaaaatt
     1261 ttaattattg tcaattaata attcttttgg attccttctt aatatattga atgaagaaat
     1321 aatcaatgat acaagaagta ctaaactcat aaatataact acataaatca tgaatttagg
     1381 taatacattg atatctaaac ttgataatgt cttgttaaat ccttcagctt ctgccccacc
     1441 acctaattgg ctagatgcag attgtttagc tatttgttta gctatatcac cagtaacctt
     1501 attcaatata ttattcccaa gcttgtcagc tgtatattga gctaagaaat aggaaccaac
     1561 gaatgcgggg attgatataa ataccatctc aattaggaat tgaccaaaaa tttctaattt
     1621 tgatatacct aatgatagta atactgctat ttctttcttt ctagcattca tccataagaa
     1681 taataataat gaaactacaa ctcctgcaaa tattaatgag ccaaaaaata atttatttga
     1741 aattgagtaa atacctgata tagattgttg taatgcaggg taatttgatg aacttttaat
     1801 caaattatat tctctccaat ttatatctaa tttcccaaga tcttttatta cactatcaag
     1861 attcttatca ccttttacaa agaatgttgc atcttggtat acagctgtat cttcggtatt
     1921 accataaact ttagcagctg tatgaatatc agtgattaat gtattttcgt at
//
LOCUS       DADGHT010000195         1889 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.203, whole genome shotgun sequence.
ACCESSION   DADGHT010000195 DADGHT010000000
VERSION     DADGHT010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1889
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.203"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(62..280)
                     /locus_tag="JX887_002841"
                     /pseudo
     CDS             complement(62..280)
                     /locus_tag="JX887_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(546..740)
                     /locus_tag="JX887_002842"
     CDS             complement(546..740)
                     /locus_tag="JX887_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258761.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
BASE COUNT          658 a          266 c          251 g          714 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtag
//
LOCUS       DADGHT010000196         1887 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.204, whole genome shotgun sequence.
ACCESSION   DADGHT010000196 DADGHT010000000
VERSION     DADGHT010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.204"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            191..445
                     /locus_tag="JX887_002843"
     CDS             191..445
                     /locus_tag="JX887_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAX1258762.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            446..763
                     /locus_tag="JX887_002844"
     CDS             446..763
                     /locus_tag="JX887_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAX1258763.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1322..>1887
                     /locus_tag="JX887_002845"
     CDS             1322..>1887
                     /locus_tag="JX887_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258764.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRK"
BASE COUNT          671 a          267 c          355 g          594 t
ORIGIN      
        1 gatgttaacg gaagtgtatg gtgagtagtt cactcgtatt ttgatatcgt ttgtatatgt
       61 tttcagcgtt ctaagtggct tattttgtcc aataataata tggagtggaa tcccttaaga
      121 aacaccgttg gcaattgttg ttataacatg ttataattta ttcatcaaaa actaaaagga
      181 gtgtgataac atgggaaaag aactaaaggt tagaaagatc ggcaatagcg tgggagtgat
      241 ccttccaagc tctcttggat taaaaagcgg agacattatc caagccaaac aagaaggcaa
      301 cttattcata ttagatacta ctcaaatagc aaaagaacac gatcgcaaat tgattgaaga
      361 aagtttccaa gactttgaga aaggtttaac agtttcagaa attgaaatgg taaaagcttt
      421 cggaaaatac ggctggagtg aatagatgaa agagtacacg ctagtttatt ctaaaagttt
      481 tcagaccagc cttgaaacga taatagaaga atgggaaaat gagcttgctc tttctccagc
      541 cagcataaaa agatttgtag gtgcgatcca gaaggcttta gaactaacca aaaattttcc
      601 aactatgcat gaggaagttt ccgaaatcta tggaatggat atcccaacat atcggatcgt
      661 gatcggcaaa agctatgcct tattttatcg gatcgaccat gaaaaaaaag agatacttgt
      721 aggacgtatt ttccaatcta aacaaatgaa actaggcttt taacaataat taggaaaaag
      781 tcgctcatcc tctacaggtg ggtgattaat gccgctcgat atggttgtta accgtcggtt
      841 actcgaagat tgatatataa gacttagtac ctttttattt tgctccatgt tatggccgaa
      901 ggtctaaaga tacaatcatt agtctagaga aaaattaaga accgtaggaa ctacggggat
      961 cgcttggtga ataagagaca ctgctattag tgaaaaaata agatatcaag tacgctctat
     1021 tcccaaaaat ttcgtgactt tactcatgag aggttcaagt agtatatttt taatcaaaat
     1081 tgacgtaact tttaataaat actacctaaa taaggtagta tttatttttg tgttttaaaa
     1141 gaggaagtcc aatatatcta tgggaaactt cttaaatatt atgttggtac atgaaaatat
     1201 acatccctgc tagactattt acaacatttt actttgtacg tattcttgtt ttaaaaggaa
     1261 tgggataaaa tataggtaca ataactattt gatgctaaat ataattaatg gaggagagat
     1321 agtgaacata cttaatgaaa aaagatatgt atggtttgct ggtaaaaaat atattactac
     1381 tttcaaaaga ttatccgagt taatgcagca gactgttaaa agtgctatgc ctgaaggata
     1441 caagtttaat tttgttcaat cttcagtatc tactgaaagt atctattttt caattctttc
     1501 tgagagtagg ctttttcatt ttagaataag ttctcatgta aagaaaactg atgttgatat
     1561 atatacgttc cgtacaaata attataaaaa tttaaatgat ttgagtagaa gtatcagtga
     1621 atatctcaag gggaatagct atctcaagat tcgattttca catatattaa ttttactacc
     1681 atatttgaat gagaatttca ccctaattca agtagataag tctttcattg cctcaggtaa
     1741 tcaaggaaat atgaatatta caagtaacaa aacgtcacgt gtgctattgg cgttgatggg
     1801 ttacggaatt ctttatagag atgaccaaaa tggccagatt ctaataaatc gggctgggcg
     1861 ttcattatta atgaaatata gaaaatt
//
LOCUS       DADGHT010000197         1877 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.205, whole genome shotgun sequence.
ACCESSION   DADGHT010000197 DADGHT010000000
VERSION     DADGHT010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.205"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            165..461
                     /locus_tag="JX887_002846"
     CDS             165..461
                     /locus_tag="JX887_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258765.1"
                     /translation="MKVDGECLTSSYKSIYEFFEEKGLDTDLLYQFYIAFRGQQLSFP
                     MKMYDRELVAQKIETMIQENHSIDSRKLTDRYGFSTRWIQSIIRQQQKEQHVHG"
     gene            454..1344
                     /locus_tag="JX887_002847"
     CDS             454..1344
                     /locus_tag="JX887_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HAX1258766.1"
                     /translation="MANEETVGLRIIEEAFKLPMVKVDRRAFLIQTFQGNVSDIEGLI
                     EKGPQAFLSKEMLDREAQKCIQSITLKSSAVSLATGLPGGIAMAATIPADLLQFFGYS
                     LRLAQEISYIYGFKDLMGETGEFSEEAKNTLILYLGIMLGVTSAGSAVRAMSGKLSTQ
                     ALKKIPQKALTQTLYYPVIKRVLGIFGTKLTKNTFAKGISKAVPVVGGVVSGGINYLS
                     MKPMATKLQTELGKNVAYTEKNLQQDLDILEGEFEEVSSDIVSSDTVLSQLERLSHLL
                     ETNMITEEEFQQLKQELLKK"
     gene            1426..>1877
                     /locus_tag="JX887_002848"
     CDS             1426..>1877
                     /locus_tag="JX887_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAX1258767.1"
                     /translation="MKAKRLFLLGTILLLGGCSTVSQNEQKKQVDSTTYETETTRKES
                     STKEIETTTQETKTTESSSKATSSDTSDFQIKQELWDTNKASQLATFVPQWGKTLGQE
                     YKSYNPQNNVSLYGTPLPSAVIDGNWKMAINEAPVTVQWSEDGTGNAG"
BASE COUNT          682 a          278 c          377 g          540 t
ORIGIN      
        1 tttcaataaa cgaaaataag tattcaatgt atatgtttct ttttctgtta ttttacttgt
       61 tcttttgcag actaaacaac ttgtaaaacc tcttgttata tgcattatca atgaaggaat
      121 caatatgata tttttaaaat gtcaggggaa atggaggtga gcaagtgaaa gtagatgggg
      181 aatgtttgac gagttcgtat aaaagtatct atgaattttt tgaggaaaaa ggactagaca
      241 cggatttact ttatcagttt tatatcgctt ttcgtgggca acagttgtcg tttccaatga
      301 aaatgtatga ccgagaatta gtcgctcaaa aaattgaaac aatgatacaa gaaaaccatt
      361 ccattgattc taggaaatta acggatcggt atggtttttc aacgagatgg attcaaagta
      421 ttatcagaca acaacaaaag gagcaacatg tacatggcta atgaagaaac agtaggtttg
      481 agaatcatag aagaagcatt caaattacca atggtcaaag ttgatcgtcg agcatttttg
      541 attcaaacat ttcaagggaa tgtttctgat attgaaggac tcatagaaaa gggtccacaa
      601 gcatttttat ccaaagaaat gctagatcgt gaagcacaaa aatgtattca atcgattacc
      661 ttgaaatcaa gtgcggtatc gttagcaact ggactgccag gaggtatcgc tatggcagca
      721 actattccag cggatctcct tcagttcttt ggttattcat tacgattagc acaggaaatt
      781 tcgtatattt atggatttaa ggatttaatg ggagagactg gagagttcag tgaagaagca
      841 aagaatacgc tgatattgta tttgggaatt atgcttggag taacttctgc aggttctgcc
      901 gtacgagcga tgtctggaaa gctgtctaca caagcattga aaaagattcc tcaaaaagca
      961 ttgacacaaa cgctgtatta tccagtaatc aaacgagtac taggtatttt tggtacaaag
     1021 ttaactaaaa atacctttgc gaaaggtatt tctaaagcag taccagttgt gggaggcgtt
     1081 gtttcaggag gcatcaatta cttgtctatg aaaccaatgg caacgaagct tcaaacagag
     1141 ttagggaaaa atgtagcgta tacagaaaaa aatctccaac aagatttaga tattttagaa
     1201 ggtgaatttg aagaagtatc ttctgatatc gtgtcttctg atacagttct ttctcaatta
     1261 gaaagacttt ctcacttgtt ggaaacgaat atgattacag aagaagagtt tcaacaattg
     1321 aagcaagagc tgttaaagaa ataattattt agaaaaagca accacttata cgggtggttc
     1381 tttttcttga atgaattcaa atttattatt aggagaagaa aaaggatgaa agcaaaacga
     1441 ttattcctat taggcacgat tcttttactt ggaggatgtt ctactgtctc tcaaaatgaa
     1501 caaaagaaac aagtggattc aacaacttat gaaactgaaa caacaagaaa ggaatcttct
     1561 acaaaagaaa tagaaacaac tactcaagaa actaaaacaa cagagtcttc tagtaaggca
     1621 acgagttcag atacgagtga ttttcaaata aaacaagaat tatgggatac aaataaagca
     1681 tctcaattag caacttttgt cccacaatgg ggaaagacat taggtcaaga atataaaagc
     1741 tacaatcctc agaacaatgt aagtctgtat ggtacgcctt taccaagtgc agttattgat
     1801 ggaaattgga aaatggcaat caatgaagca ccagttactg tacaatggtc agaagatgga
     1861 actggaaatg caggatt
//
LOCUS       DADGHT010000198         1847 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.206, whole genome shotgun sequence.
ACCESSION   DADGHT010000198 DADGHT010000000
VERSION     DADGHT010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.206"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            700..>1847
                     /gene="ltrA"
                     /locus_tag="JX887_002849"
     CDS             700..>1847
                     /gene="ltrA"
                     /locus_tag="JX887_002849"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004853597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAX1258768.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQK"
BASE COUNT          730 a          281 c          384 g          452 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaaga
//
LOCUS       DADGHT010000199         1814 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.207, whole genome shotgun sequence.
ACCESSION   DADGHT010000199 DADGHT010000000
VERSION     DADGHT010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1814
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.207"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(134..1282)
                     /gene="tnpB"
                     /locus_tag="JX887_002850"
     CDS             complement(134..1282)
                     /gene="tnpB"
                     /locus_tag="JX887_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAX1258769.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(1299..1703)
                     /locus_tag="JX887_002851"
     CDS             complement(1299..1703)
                     /locus_tag="JX887_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HAX1258770.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          538 a          317 c          291 g          668 t
ORIGIN      
        1 tgacggttct taacgcttga agtgggagct tcttgggaat agagcatact tgatagcgta
       61 tttctttact aacagcggtg tctcttattt accaagctat ccccgtagtt cctacggttc
      121 ttgatgattg gatctaagcc aatcccatag aatgtagtct tagaccttcg gtcagaatat
      181 tgatactagc attgatatca cgatcatgat gagtatgaca aacaggacaa gtccattctc
      241 gaatttcaag agatttcttg ccatctttat gtccgcactc tgaacaaatc tgactagacg
      301 gaaaccattt atctactttg atgatttttc gtccatacca gtcagccttg tattgtaatt
      361 tagtcacaaa ctttgaccaa gaaacatcag aaatactttt agctaattta tgatttcgca
      421 acataccttt tgtgtttaag tcttcaatac agataatatc gtgatttttg atcatttctg
      481 tactcaactt attcagaaaa tcagtacgtt gattcattac tttttcatgc aatctagcta
      541 ctttgcgttt ttgtttttga taatttttag cttcaaatag attggtacct ttatttttag
      601 ccaataaagc acgcctagac aatttgcgtt gttcacgctt tagtttcttt tccattttgg
      661 acgtgaattt attattatca attttttgtc catcagaaag aatcgcaaag tccataatac
      721 ctaagtcaat accaattgtg gaattagttt taggtaattc gataatttct tctttacaca
      781 acaaagaaat atagtattta ccgctagaat gacgtgatat tgtagcggat ttgataatcc
      841 cttttggttg tctatgaagc ttaattctta ctaatgactt caatttagga actttgatga
      901 atttactatc aatcaaagca actgtaccat tttgattatt cgttgtataa ctctgaacag
      961 gatttttctt acttttgaaa cgtggaaatc caacggattt atcccgaaaa aaattcttgt
     1021 atgctttatc taaattaagt tgggcattgg ctaaagcaag gctatcaatt tctttcaaaa
     1081 acggaaattc tttcttgtat ttagctggtg tcggaaaagt cattttttta gaagaatcat
     1141 ttttaacttc ttcatacgcc ttttttcggt catcaagcat tagattgtag accttacgga
     1201 cacaaccaaa agatttggca aagaagattt cttgttcctc tgttggatag attctgaatt
     1261 tgtatgcttt tagttgttcc ataaagttca cctactttct atttatgatt gtttccttga
     1321 ttttggatat acttcttaat cacatcaatt ggtgcgccac cagttgtcag aagacaaaaa
     1381 cttttagacc agaacatttc tttccaaaga aattgtttga ctcttggaaa gtcacgtttt
     1441 atcaatcttg agctggcact tttataggca ttgatgaatt ttgtcaattc tgttttaggt
     1501 tgagctttga acataatatg aacgtggtct ttatcatgat tccactccac taaagtaatg
     1561 tgatacgatt ctgaaattct ttcaaaagta gttttggcat aatcagatat ttcatcatca
     1621 atcacttgtc tacgatattt cgttactaaa acaaggtggt aataaagaag aaatactgaa
     1681 tgattatttg tatctaattc catgttatat caactcattt cttgtataga ctgattgtaa
     1741 catggaacaa aataaaaagg caatacgcct tagttgtcgg tcttcgagtt accaacggta
     1801 accctcatac cgaa
//
LOCUS       DADGHT010000200         1802 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.208, whole genome shotgun sequence.
ACCESSION   DADGHT010000200 DADGHT010000000
VERSION     DADGHT010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.208"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            275..1753
                     /locus_tag="JX887_002852"
     CDS             275..1753
                     /locus_tag="JX887_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAX1258771.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT          654 a          252 c          322 g          574 t
ORIGIN      
        1 taaaagagca ggacggtggc cgtcctgctc ttttttgtgg ttgtttacgc aaatggcgca
       61 aatcttgtac attttaacac aataaaacaa aaaatataga atatttcctc ataaattttt
      121 ccattttttg caatattctc aaaaaaaaga taaaaaatga gaataactga tgaaaaaaca
      181 agcataatcc atcataaaat cagtataggt gaaaagatga actttcatct gcatatcaag
      241 taattggtat gaggcatttt ttgaggtgta ggatatgaag ttggattacc ttatagaaga
      301 ggaagataga gaaaaactgc tgctagctag atatttagaa tttgagaaaa agaattatgt
      361 agtgctgcct aagttatatg aaacattagg tttgtctaaa tttaaaacaa gaaattatat
      421 catagaatta aataaagaat ttactgaatt caaaacaaag ccagagatcc aaatttcaga
      481 agaagcagag atccatgtcg aacgtctgaa tttgacggat atcaaaaatt taagaagaat
      541 ctactttcaa cgatcaaaaa ttgctcgact gttaacggag atcgtggatt caaaagtaac
      601 gatcgaaaaa tttgcagaga atcatttttt aagcatatca agagcctatg taaaaagaag
      661 agaattagtc tcttttcttg aacagcatca aataaagtta aagaaaaaca tattagttgg
      721 ggaagaaata aacatacgga acgtattatt tggggtatat ttcggggtct ttaatggttt
      781 ttctatgcca tttagagaaa gcgtcatgaa tgaagcaaag agtatcgtgc aatattttga
      841 atatctgttc aatttaaaac tgtctgcaac aaaacgaatc aaattcaatt tgctaaccac
      901 tattagtttg ttgagggcct atgggaatca accaatcgga aaacgtttct tttcagatga
      961 atactttaag agctcagaag gaatgaagat catcaaggat ttatcacata tttcttttct
     1021 tcatatccct aaagagcaga tcattgatga gatttcttat atcatgttgt ttttgatcac
     1081 ggaagaagaa tttgaattag atggcgcatt tggacttgcg gaagctcatt ttcatgatat
     1141 ccacatgatt agtcaaaaaa tgtcagtgga attgattgat caattaccat tttcgattga
     1201 aatctctgaa gaagaaagac tatatatacg aaaagaactt cgtatgggta tgatgcatgt
     1261 caatcgaaaa aattggatat tcgactttga gatgactagc tttacgtcta aaaagcagct
     1321 acagtttttc ttcgagacgt atccaatatt cagtacagca atccaaaagg tcatacaaga
     1381 gaataaacgc tatttcttgg gaaaagatga acgtttcatg attcgcttat tttatgatta
     1441 tctcttttta ttggtcggta tttgtccggt atcatatttt gaagcaccga ttcatgtctg
     1501 tattgatttt tcgcaaggat ctgcttatac cgattacatt atttctcaag tgaaaggatt
     1561 taaaaattac aatattgtga ttgagagtcg aatcacttct cgtacgaata tttatttatc
     1621 tgattgttta cttgaaaaat ttaataaaga acagataatt tggaaaaatc caccgactcc
     1681 agatgactgg gaatattttg gaaataccat catcagagaa aaaaatagac atttaactga
     1741 aaaaatcagc tagtatttat ggatggcagc tttgtctcac atatttatta gctgatttat
     1801 gt
//
LOCUS       DADGHT010000201         1795 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.209, whole genome shotgun sequence.
ACCESSION   DADGHT010000201 DADGHT010000000
VERSION     DADGHT010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.209"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            133..507
                     /locus_tag="JX887_002853"
     CDS             133..507
                     /locus_tag="JX887_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAX1258772.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(621..1250)
                     /locus_tag="JX887_002854"
     CDS             complement(621..1250)
                     /locus_tag="JX887_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAX1258773.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1384..1456)
                     /locus_tag="JX887_002855"
     tRNA            complement(1384..1456)
                     /locus_tag="JX887_002855"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1421..1423),aa:Thr,seq:ggt)
     gene            1670..1743
                     /locus_tag="JX887_002856"
     tRNA            1670..1743
                     /locus_tag="JX887_002856"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1704..1706,aa:Asn,seq:gtt)
BASE COUNT          621 a          263 c          314 g          597 t
ORIGIN      
        1 gtctacactc tgagatgtaa gaaatatcat aagatatttc ttacatcttt ttgttttgag
       61 caggacttta gataatttta ttaatatatg ctagcatgct tttgtaagaa aaagaaagag
      121 ggcgtattag ttatgtatct taaaattacg gaacaagcac aagaaagatt acaaaaatat
      181 attgatgaag gcgcaacagt tatattggat ttagatgatg gcgttgggga atattctaaa
      241 atgggtgttt gctctttaga tactagtttt cgtttacttc ttcttgataa agaacagaga
      301 aaaaatgatt ataaactcca attagatagt gatattgggg atgtttatat aaaagattat
      361 tcaaaaatgt acatggatga acatatgacc ctttctttag atccacgtct aggtgtattt
      421 actcttgaaa gcccaagtgg ttctttagac agtcatgttc aattagtaga tctacgacca
      481 gaaaaattct ctggaataaa acaataactt tctctctatt gtccataaaa ctagtctcaa
      541 tcaagctgta ttgaaaaaac aagacaacat tcttaccatg gtaaataaaa agacgacaca
      601 ttttgtcgtc tttttttaaa ttaactattt tcgataaaag atcgcatagc ttgtgccatt
      661 atttctggct tttctctatt caattcatgt tttccgtttt taataaagag tagccggcca
      721 ttcgttgaaa gtttatataa acgttttgct gctggtttat tcgcatgatc tttggtaccg
      781 cataaaatca atttaggaag tcgtgatgta cgaagctgtt ttttgcagtc taatgtttca
      841 agtgaacgaa gtagggtaag ggtttgtttt ttagatagac ctaatttttc aaatatctta
      901 gaaggtacgc agtaaaaata aatattctgg aaagtaagca ataagcgatt aggagactca
      961 aattgtggag cgactaaaac aacctttttt aaatatggag aaggagttgc aagatagttt
     1021 aaagcaataa cagcgcctaa agataatcca cataaaataa aaggttcctt tatctgattc
     1081 aattgtactt cgatgtattt ggttaagtcg tctaaagtag cagtgtctgt gctgtttaaa
     1141 tgattgaaca atgaaagact tttgcaagaa taactattgg gtagataaga gattacatct
     1201 ttccatgatt gttcgtcttg gcctagacca tgcaaaaaaa caattttcat attgctctcc
     1261 tttttatagt tatcatatag actttctttg tactattaaa atataaacat tcatttctta
     1321 cgtcataaaa taaaaaaaca gcgcagacac attgttaaac caacatgttg cactgtttaa
     1381 ggaagccact tgccgggctt gaaccggcga cctcttcctt accatggaag cgctctacca
     1441 gctgagctaa agcggcatta tcattaatac aaataatagg ataacgaata ttaatgtatt
     1501 tgtcaacaga attttttcga aaaaatgtgt ttctctaata ggaaaacaga ttttagaaaa
     1561 aataaaaata acaaaaaatg cgaacggttt ctttgataat ataataaaaa aattcaaaaa
     1621 aagtattgcg ttatttagaa gaaattgata ttatattcat gtacttgatt ccggcatagc
     1681 tcagttggta gtagcgcatg actgttaatc atgatgtcgt aggttcgagt cctactgccg
     1741 gagtaaataa agcttatgca aagaaaaaga aatccaatca cttgggtttc ttttt
//
LOCUS       DADGHT010000202         1773 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.210, whole genome shotgun sequence.
ACCESSION   DADGHT010000202 DADGHT010000000
VERSION     DADGHT010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1773
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.210"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            81..1604
                     /locus_tag="JX887_002857"
     CDS             81..1604
                     /locus_tag="JX887_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HAX1258774.1"
                     /translation="MDPTVFEAEEHIQKVIHKMFRPDNAYTKFDFRNGRPTKSAILTT
                     SSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTMEDPDFPRIAITYSLEENSRD
                     SSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNRLARKRAEFKQFGKQIDLVIV
                     VDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTYPEKTKGLIVTFRKPATMEKN
                     VEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKEVSSMESIDEHTPLEIRIEYV
                     KAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEEQIGVYETVKGSLMEEEPEKE
                     GEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSDAREEIEKALAKLNKTEGVKE
                     VYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHAFSNEWFVSEKELHASNLQYM
                     PGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMKRAWRKMLDDELIPLENELR"
BASE COUNT          641 a          285 c          359 g          488 t
ORIGIN      
        1 tagaaacata tgcagagtat tcaccggaac agatcaatcg tatgatcgat caaatggagt
       61 ctgtcaaaaa agaaagttat ttggacccta ctgtttttga agcagaggaa catatccaaa
      121 aagtcattca taaaatgttc cgtccagaca atgcctatac aaaatttgat tttcgaaatg
      181 gccgtccaac gaagtctgcg atcttaacca cgagttccat tgatatggcc aaaaagtatt
      241 atcgggccat caaagagatg acgaaagaat ctgattggtt aataaaagag tttcccaatc
      301 agcctatccg tgaaggacga acgatggagg atcctgattt cccacgaatc gctattacct
      361 attcattaga agaaaatagc cgagattcaa gtgcccaaca agaagaaatg caaaaaatta
      421 ttgaggaata taatcagtat tatgatactg cctggtcact agcagacatt gagcgttata
      481 acggagacat caataatcgt ttggcacgaa aaagagcgga attcaaacaa tttgggaaac
      541 aaatcgattt agtaatcgta gtggatcgtc tattgacagg ttttgacgcc cctacgattc
      601 aaaccctatt tgtggatcgt aatctagagt atgcaggatt gatccaagcc ttttcacgta
      661 cgaaccgtac gtatcctgaa aaaacaaaag gactaattgt tactttccga aagccagcga
      721 caatggagaa gaatgtcgag gatgcgacaa aactgtattc agaagctaaa gaagaatcgg
      781 gtttgattta tccaagttac caagaatcca aaaaaagatt caagcaagca tatggtaagt
      841 taaaagaggt ttcatccatg gaatccattg atgaacatac gccacttgaa atccgtatcg
      901 agtacgtcaa agcatttcaa gaattgaatc gtgcgtatga atcgttagtg acttatgatg
      961 attacaatga tgacatggtg caatcttcaa ctttgaacaa tcaaattcaa cttttggaag
     1021 aacaaattgg cgtgtacgag accgtgaagg gttcattgat ggaggaagaa ccagaaaaag
     1081 agggagaaga tttttcaacg atcgaatttt atagtgaaaa taccactaag ttgtatgata
     1141 ttgattctac ttatattgat caattactag gaacttatgc tgcgaatagt tcagatgcac
     1201 gagaagaaat tgaaaaagct ttggctaaat tgaataaaac agaaggagtc aaagaagttt
     1261 accgacaaat tttaaatgca tttgatgtgg ggactttaga tagtaatgaa gatatctttg
     1321 tcattaaacg tcgctatttt acacaagcaa gtgataattt gattcatgcc ttttccaatg
     1381 agtggtttgt ttctgagaaa gaattacatg cttctaatct gcaatatatg ccaggtgaag
     1441 atccaattcc taatatgaaa gcaattatca acagtaagga ttacgaagga tataaagcca
     1501 aacatccaga agcgaaacca tttaaatacc cacaagaaat gaagcgagca tggcgtaaaa
     1561 tgttagatga tgagttgatt ccacttgaaa atgaattgag gtaaacgaga agagttaaga
     1621 aaattgtacg attcaaagat agtagtaaag tggaagtgta gaaaataggg atagatgtct
     1681 ttttacttgt tcacatttta taacggagta tttaagaaag ctattgaata atgattcttc
     1741 catctttttc attcatttac cggttctgtt gca
//
LOCUS       DADGHT010000203         1699 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.211, whole genome shotgun sequence.
ACCESSION   DADGHT010000203 DADGHT010000000
VERSION     DADGHT010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.211"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..240)
                     /locus_tag="JX887_002858"
     CDS             complement(<1..240)
                     /locus_tag="JX887_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HAX1258775.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFT"
     gene            complement(324..>1699)
                     /gene="uxaC"
                     /locus_tag="JX887_002859"
     CDS             complement(324..>1699)
                     /gene="uxaC"
                     /locus_tag="JX887_002859"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAX1258776.1"
                     /translation="HKFAKHQPIIDYHCHLDPAYLLENKQYKNLTQVWLNDKGAGDHY
                     KWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPIFEWSHLELQRYFDIDLTI
                     SEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDDPTDDLWYHTELSKQDNSF
                     KVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGLKQALSQRVDHFHQIGCRL
                     ADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQFVTGIQLHLMSEYTRYGWT
                     MQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVALFDTAEKSGCLPKTILYS
                     LNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMRQQLTTMAQQSLLSNFTGM
                     LTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYLSQIVENICYRNAYNYFNF
                     FEIGSRK"
BASE COUNT          513 a          359 c          240 g          587 t
ORIGIN      
        1 agtaaacgca tctaaaaccg taccggctcc gattattaca tctttttgat cagcatattt
       61 tttagcaatt tctttgatta tttcttcagc attaggaact gtaaaagtta gttcaatccc
      121 tttaattcca cccgcaataa ttgaatttat tgctttaatg gcctcatcct tatttttccc
      181 acgtacaacc gcaatgactc cagccgcttc taacttactt aaaatttcta cttttttcat
      241 atctatctcc ttcctttatg gatacatact ttgtctagct gtactaactt acaaagaata
      301 aatttaagct tttatttcaa gtattatttt ctacttccga tttcaaaaaa attaaaataa
      361 ttatacgcat tacgataaca aatattctcc actatctgac taagatacat ttcatcatct
      421 ggaattcggc ctgctttaac ccactcgctt agtaattgac ataatactcg acgaaaatac
      481 tcatggcgag gatagcttag aaaacttcga gaatcagtca acatacctgt aaaattcgac
      541 aacaaacttt gttgtgccat cgtagtcaac tgttgacgca ttccttcagc tgtatcattg
      601 aaccaccaag cacatcccaa ttggattttt tgaatcatac ccccttggaa gctttgcatt
      661 gctgttgcta gtggaagcca atcagttgga tttaatgaat ataaaattgt ttttggtaag
      721 cacccactct tttcagcggt atcgaacaat gctacaacat tttgtgtcaa actagcttga
      781 tcccccatcg aatcaccacc gacatctact ccaatttgtt cctttaatat acttgaatta
      841 tttcttaaag catttaaatg catttgcatc gtccaaccat atcttgtata ctcagacatc
      901 aaatgtaatt gaatacctgt aacaaattgt gcaatttctg ataaatggaa atccgttttt
      961 cctgctaaag cttttattaa cagattgtcg agtatttttt catctgctat ttcataaaaa
     1021 taagtattca aaccgtgatc tgctaatcga cagccaattt gatgaaaatg atccactcgt
     1081 tggctcaatg cttgcttcaa cccattaaag tctttgattg gtatagccgc tgtttgacta
     1141 agttttaaaa tatagttcga aaagcctgat gatttgatac tccagacctt atctggacgg
     1201 aaagtaggta ataccttgaa agaattatcc tgtttagaaa gctcagtatg ataccacaag
     1261 tcatctgtag gatcatccgt tgtacagatg gctttcacat ccatcatctc caacaattct
     1321 ttcgggcgat aggaatccgt ttgaattttt tcgttagcac gtcgccaaat ttctggtgca
     1381 ttcttctcag aaattgtcaa atcaatatca aagtaacgtt gtaattccaa atgagaccat
     1441 tcaaaaatag gattacctgg cgccttctcc actgttttta caaaagctaa aaatttttca
     1501 taatcatcac ctggaccact gatcaactct tcttctatac cattagctcg catcaatcgc
     1561 catttataat gatctccagc tcctttatca tttaaccata cctgagtcaa attcttgtat
     1621 tgcttatttt ctagcaaata tgctgggtct aaatgacaat gatagtcgat aattggttgg
     1681 tgttttgcaa atttatgaa
//
LOCUS       DADGHT010000204         1673 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.212, whole genome shotgun sequence.
ACCESSION   DADGHT010000204 DADGHT010000000
VERSION     DADGHT010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1673
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.212"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..712
                     /locus_tag="JX887_002860"
     CDS             <1..712
                     /locus_tag="JX887_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAX1258777.1"
                     /translation="TPFDEESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLL
                     STGMADIHEVSEAVDCFIDSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSD
                     HSLGYDVGICAVAMGAKVIEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLG
                     DGVKRAMPSELSTKEVSRKSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGK
                     KVKRPISADSVLLEEDVE"
     gene            709..>1673
                     /gene="neuC"
                     /locus_tag="JX887_002861"
     CDS             709..>1673
                     /gene="neuC"
                     /locus_tag="JX887_002861"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAX1258778.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANL"
BASE COUNT          597 a          222 c          331 g          523 t
ORIGIN      
        1 tactcctttt gatgaagaaa gtgcagactt tctaaaacaa attggtgtac aaggatttaa
       61 aattggctca ggagatttaa caaatttacc ttttcttaga aaaatagata tgtatgggtt
      121 gccagtttta ttatctacag gtatggctga tattcatgag gtcagtgagg ctgtagattg
      181 tttcatagat agtccagtta ctattttaca ttgtacttca aattatccgg ctagttctga
      241 agatattaat ttattggcga ttaacacatt aaaagaaatg ttcgggatac ccgttgggta
      301 ctccgatcat tcattgggat atgatgttgg tatttgtgct gttgcgatgg gtgctaaggt
      361 aattgagaaa cattttacct tggataagga actacctggt ccagatcata aagcttcttt
      421 agatcctcag gaatttgcag attttgtaaa gcatattaga aacactgaaa tatttttagg
      481 tgatggtgtt aagcgagcaa tgccttctga acttagtaca aaagaagtat caagaaaaag
      541 cctagtggtc actgagaatt taaatgtggg agatattctt acagagaaat ctcttacaat
      601 aaaacgtcct ggaaatggaa tagctcctaa gtttttatat caatatattg gcaaaaaagt
      661 taaaagacca ataagtgcag atagtgttct gcttgaggaa gatgttgaat gaaaaaaata
      721 cttatagtaa gtggaacacg agctgattat ggaatatata aacctgttgc tgagaattta
      781 ctacaagata attgggatgt atcatttgtt gtttctggaa tgcatttatc ccataaatat
      841 ggatttacta aagaattgat cttagctgac ggatttagaa ttagtggaga agttcaaagt
      901 ttgtttttag agaacaataa gggaaacatg gctcggtctg tggcattaga gataaatggt
      961 ttcacaaata tatttgaaca aactagccct gattttgtat tattactagg ggatagagga
     1021 gaaatgttgg cagctgcgat agcttgtttg tatcttggaa tcaaaacagc acatattcac
     1081 ggaggcgaag tgtctggtac tgtagatgaa tcaataagac atgccataac gaaaatagca
     1141 tctgttcatt ttgctgctac ggaaaaaagc aaagagcgtt taataaaaat gggggaagat
     1201 tcttggagag tttttcccgt cggagctcct agaatagata ctattttaaa taatagatta
     1261 cctagtttta gagatataaa agaaaaatat catctaaaat ttgaaaagaa aaaatacgtt
     1321 ttgcaagtat ttcatccagt tgtaaccgaa ctagaaaata tagaaaaaca aattttagct
     1381 ttgatcaatt caatggaaca acaatctcaa ccaattattt gcattttacc taatagtgat
     1441 gctggtagcg aaattatcag aaaaatgtac cagaaatatt taaaaacgga tattatttat
     1501 attacgaatt tagagccgga ggaatacctg actatattaa aagagtgcaa atttatgatc
     1561 ggaaattctt cttctgggat aattgaagct gcatcattca aaataccagt aataaattta
     1621 ggaaccagac aaaatggacg agaacaatct aaaaatatta taaatgcaaa tct
//
LOCUS       DADGHT010000205         1656 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.213, whole genome shotgun sequence.
ACCESSION   DADGHT010000205 DADGHT010000000
VERSION     DADGHT010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.213"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..394
                     /locus_tag="JX887_002862"
     CDS             <1..394
                     /locus_tag="JX887_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAX1258779.1"
                     /translation="FCKVCDRKEGFCGFRIDIKELAKVSDIFLFTTLQEGMPRSMMEA
                     MASGLPCIASKIRGNVDLLVEGKGGYLVPAKDAELVAECLRELINNKSLRKYMGNENL
                     SRIKEFEVSIVKKRIKEIYEEVIGESVK"
     gene            391..1392
                     /locus_tag="JX887_002863"
     CDS             391..1392
                     /locus_tag="JX887_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1258780.1"
                     /translation="MKNPMFSIIVPIYCVEKYLKDCLDSIRNQTFKNFEAILVDDGSP
                     DECPEICDYYSQIDGRLKVIHKKNGGIIDARKTGVTSAMGEYIVFLDGDDWLANTYLE
                     KYAEVITKYNPDIICSGYFASRSNKIRKRELSCSFGYYDKDKIINLIYPKLIEDEHGE
                     YFRPQLWAKAFRTTLYKEQQQVSGQVSVGEDHACTKPCIYHANSIYMMEKCLYYYRIN
                     ENSITKKPQPYYWEGPKAIGEHFEKQIDMNKYDFQDQVYRNVTHNLFNVAVSQFNKQD
                     KYLNIKKDIIQNLSDEYYTRAICKCKYKDNWKGISAKFALKNKWVFLIYIYNKLIKR"
     gene            1398..>1656
                     /locus_tag="JX887_002864"
     CDS             1398..>1656
                     /locus_tag="JX887_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAX1258781.1"
                     /translation="MSVKISVIVPCYNVEKYIDECINSLINQTLKDIEIILLNDGSTD
                     NTLAILKKYEKLDSRIKVYEHKNMGLGPTRNRGIKIANGEFL"
BASE COUNT          664 a          172 c          318 g          502 t
ORIGIN      
        1 gttttgcaaa gtatgtgata gaaaagaggg attctgtggc ttcagaatag atatcaaaga
       61 attggcaaaa gtttctgata tttttttatt tactacatta caagaaggaa tgccaagatc
      121 tatgatggaa gctatggcaa gtggattgcc atgtatagca agtaaaatcc gaggtaatgt
      181 agacctttta gtggaaggaa aaggtggata tcttgttcca gctaaagatg cagaattagt
      241 agcagagtgt ttgagagaac taatcaataa taaatctctt agaaagtata tgggaaatga
      301 gaacctttcc agaattaaag aattcgaggt tagtatcgta aaaaaaagaa tcaaagaaat
      361 atatgaagaa gttataggtg agagtgtaaa atgaaaaatc caatgttttc aataatagta
      421 cctatctatt gcgttgaaaa atatttgaaa gattgcttag attcaataag aaatcagaca
      481 tttaaaaatt ttgaagcaat actagttgat gacggtagtc ctgacgaatg cccagaaata
      541 tgtgactatt attcccaaat agatggacgt ttaaaagtaa ttcataagaa aaacggtgga
      601 ataatagatg cacggaaaac aggagtcact agtgctatgg gagagtatat agtttttcta
      661 gatggtgatg attggcttgc aaatacttat ttagaaaaat atgcggaagt aattactaag
      721 tacaatccag atataatatg tagtgggtat tttgcatcac gttccaacaa aattagaaaa
      781 agagaattgt cttgctcgtt tggatattat gacaaagata aaattataaa tttgatttat
      841 cctaaattaa ttgaggatga acatggagag tattttagac cacaattatg ggcaaaagct
      901 tttagaacta ctctgtacaa ggaacaacaa caagtatctg ggcaagttag tgttggtgaa
      961 gatcatgcat gtacaaaacc atgtatttac catgcaaatt cgatatatat gatggaaaaa
     1021 tgtttatatt attacagaat aaacgaaaat tctataacaa aaaaaccaca accatattat
     1081 tgggaaggac caaaggctat tggagagcat tttgaaaagc agattgatat gaataagtat
     1141 gattttcaag atcaagtata tagaaatgtt acacacaatt tatttaatgt tgctgtttca
     1201 caatttaata aacaggacaa atatttaaat ataaaaaaag atattataca aaatctaagt
     1261 gacgaatact atactagagc tatttgtaaa tgcaaatata aagataattg gaaaggaatt
     1321 agtgctaagt ttgcattgaa aaacaaatgg gtatttttaa tttatattta taacaaattg
     1381 ataaagaggt aataataatg tcagttaaga ttagtgtaat tgtaccttgt tataatgttg
     1441 aaaaatatat tgatgagtgt ataaatagtt tgataaatca aacattgaaa gatattgaga
     1501 ttattttgtt aaacgatggt tcaacagata atacgttggc gatattaaag aaatatgaaa
     1561 agcttgattc tagaataaaa gtttacgaac ataaaaatat ggggttaggg ccaactagaa
     1621 atcgagggat caaaatagct aatggagaat ttttgg
//
LOCUS       DADGHT010000206         1652 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.214, whole genome shotgun sequence.
ACCESSION   DADGHT010000206 DADGHT010000000
VERSION     DADGHT010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1652
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.214"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            415..>1652
                     /gene="ltrA"
                     /locus_tag="JX887_002865"
     CDS             415..>1652
                     /gene="ltrA"
                     /locus_tag="JX887_002865"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAX1258782.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKA"
BASE COUNT          590 a          301 c          392 g          369 t
ORIGIN      
        1 acttggtggt gaaagtccac tacaggcttg gcagtaggaa ctgttagcga aagacaaggc
       61 ggcaatcgtg aggttgtggc tgaaggaagt cggacgcaaa ctcctgaact gacgaacaga
      121 aactagatac aaggctgaat taggtcggat aagtcttcat cacaagacaa agtccaatac
      181 tgcccgaaac ctatacagta aatctagcag ttacatggga ggaaagtttt cactcttacc
      241 gggggagatc tcatgagggt gttgtgggcg ttgaatgaaa acaaaccagc acaacgatca
      301 tggcgacatg atggtgaatc atgagaagtc agccgaggtc atagtagtaa cgacactgac
      361 cgttacgaag gactgaacaa taagaatctt gaataattta ggaggtgtga gaagatgcga
      421 cgaccgcaga aaacaagaaa acttggctat catcaaagag ctagtgtgga acacgaaggg
      481 tatgatgaag tgcgcagcac ttcttgcggt gaacagagga aacaagatgg tgtagaaaat
      541 ctgtttggga gaattctaga tcggaataat ctcaatcaag cgtatcttca agtagtcaga
      601 aataaagggg cggctggtgc agatgggatg accgtcgatc aactgcttcc ttacttgaaa
      661 gagcaccgcg aggaattact atccaattta cgccaaggga actataaacc tcagcctgtt
      721 ttgcgagtag aaataccgaa accaaacggc ggtgtaagaa aactaggaat tcccacggtt
      781 attgatcgta tgcttcaaca ggcaatcaat caagtgttac aaccgctatt tgaaccagaa
      841 ttctcagata atagttatgg gtttcgccca aatcgcagcg cacatgacgc agtgaagaaa
      901 gcaaaatctt attatgaaca aggttaccga tatgtggtgg acattgatat gaaagcctac
      961 tttgacaccg taaatcacga taagctgatg tatttcattg agcggaaagt aaaggacaaa
     1021 caagtcctaa aactgatccg tcaatactta atgagtggtg taatggaaaa tggactcatc
     1081 acaacaactg aagaaggaac gccccaagga ggcaatctct ctcccctgtt aagtaacatc
     1141 tacctgaacg aatttgatca agtgctagaa aatctaggac ataaatttgt tcgatacgcc
     1201 gatgactgca atatctatgt tagaagcaaa cgagcaggac agcgtgtgat gaagaaatcc
     1261 attcaatttc tcgaagaaca actaaagttg acggtaaatc gagaaaagag tgcggtagga
     1321 agtccattga aacgaaagtt tcttggattc tgcattctgc caacaaagaa aggtattaaa
     1381 attcgccctc acgcaaaagc aaaacagcgt gtgaaaagca agctcaaaca actcactaaa
     1441 agaaaccgtg gaagaagtat ccaacttatt ttaaaagaaa tcaagcaact aatgactggt
     1501 tggatcaact actatggaat tggtgagatg aaagaattca tgagggagtt aaacggttgg
     1561 ttgaagcgaa gaatcagaca atatatttgg aaacaatgga agaatccaag aaccaaaaga
     1621 aaaaatctga ttcgtttagg gatcgataaa gc
//
LOCUS       DADGHT010000207         1610 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.215, whole genome shotgun sequence.
ACCESSION   DADGHT010000207 DADGHT010000000
VERSION     DADGHT010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1610
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.215"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            7..267
                     /locus_tag="JX887_002866"
     CDS             7..267
                     /locus_tag="JX887_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258783.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(629..868)
                     /locus_tag="JX887_002867"
     CDS             complement(629..868)
                     /locus_tag="JX887_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258784.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            1154..1468
                     /locus_tag="JX887_002868"
     CDS             1154..1468
                     /locus_tag="JX887_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258785.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          553 a          219 c          282 g          556 t
ORIGIN      
        1 tgaaatatga ataacgaaac tatcatttta ggaaaaaaat atatttgcca acctattggc
       61 ttgaaacaaa aagtgattgg agaagtaatc agtaaattag aaaattgtgt tgtgatctgc
      121 gtagacgaat atcatgacgt cgatcgcaat gaaatattag aaaaatgcgg aaaagtagtg
      181 gcaaaatata ctcacgttta tgagttggaa acaacagaat atctatataa ctatagcaac
      241 aaatatgaac atactttagt ttcataaaga tttaaataaa gtgccttcaa aagcgagaag
      301 accaagcttt tgaaggcact ttatttagtt ggcagtgatt gttcatgatt tttgatttat
      361 tcaaaaggtt cgcctagaga atctgtctct gtaacgaggc ctggtggaga aactcgataa
      421 aaacctatac tgccagaact gtcctatttt cggatagaca aactagtagt tttaaaaaga
      481 tcatccgatc caatcatttc aaaaaatgca aaactgatat caggatcatt tagctcaggc
      541 ttgttatcgt aaagcatttg taaaggttgc atttagttag gagtaaacgc gaaactatca
      601 tcattatttg ctgaagaaga tgaagaagct aattcagagt ttgtttgaaa taaaggagac
      661 gtgctgacag tttctttacc ctgttttttg cagaggtaga aacttttata tcggaagttt
      721 ctaccggaga atttttctca tttgtagaaa ttgttgaatc gatactattc gaaatttgcg
      781 tatctgaagg tatgttcttt gatgcagaag tcccacaagc agtaagtaac aataaatttg
      841 ataaactgat aaacagaatt cttttcatta tgtacacact ccttatagta tcgtttagca
      901 tacacctatg ctcagtatta ggcaaaatca atgcaaaact atcaagtctt ttatagtatc
      961 tattagtctt agtaatacat atatggagag ggtgatatcc cagttcaaac cagatacatt
     1021 ggttaccatc tgtattaacg attatgcctc taaacgcttt ttttatgaaa aaatttataa
     1081 gtgaaaacgt aggtatgata ttatctagag gtaatttttt tgggtattta aatagttgct
     1141 aggaggatag cttttggatt tttacagtaa ttttatctta ataatagcaa tattattact
     1201 tctaaatatt tggttttttg ataagagtag aaatgcaggg ataggtttta gaaccaaacg
     1261 aagtacgtct tctgaaaaaa agtgggtata ttcacagact attttttacg gaggggttat
     1321 ttcaatcagt ttactttctt caacacttta ttcttttaat gttatagacg tttccatgtc
     1381 aaattttata tctattattg gaatccttat ttctgcaatt attacacaac tacttcttgt
     1441 gtttgaagag aagtcaaaaa ataattaaag caattatgcc ttttagtaca ggaattatta
     1501 cttcttacaa atgtatagcg aatgtgaagc ctgctgtttt aattgttcta gaaaaacttt
     1561 tgagtgaaca attattttat gttaggatga attaatttct ctagagttta
//
LOCUS       DADGHT010000208         1574 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.216, whole genome shotgun sequence.
ACCESSION   DADGHT010000208 DADGHT010000000
VERSION     DADGHT010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.216"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..342
                     /locus_tag="JX887_002869"
     CDS             <1..342
                     /locus_tag="JX887_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HAX1258786.1"
                     /translation="GFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLEILTTVFTEKKIN
                     TIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLSHPLSIHVRNEWQ
                     LADSQLLFQEK"
     gene            488..781
                     /locus_tag="JX887_002870"
     CDS             488..781
                     /locus_tag="JX887_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258787.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            774..1070
                     /locus_tag="JX887_002871"
     CDS             774..1070
                     /locus_tag="JX887_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258788.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            1145..>1574
                     /locus_tag="JX887_002872"
     CDS             1145..>1574
                     /locus_tag="JX887_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAX1258789.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTG"
BASE COUNT          581 a          215 c          318 g          460 t
ORIGIN      
        1 ggatttactg gttttattgc tgtgaatctt ttttcgtaca caaaagcgaa aagtcctcgg
       61 gtatttcttc gaggaaatga tgaacaatct ttggaaatat taacgactgt ttttacagaa
      121 aagaaaatca ataccattat ttttgcttgt ggttcgatta cagcgacgag tcaagtggct
      181 tatgaacaag caaagactat ttacgatcaa ttgagtgcga aacaaaagaa gatgaccaaa
      241 gtattgataa atgcagaagg taagttatcc cacccactaa gtattcatgt tcgtaatgaa
      301 tggcaattgg cagatagtca attattattt caagaaaaat aacattttat tttctcatgt
      361 tacttataag tagttttaca tgctttttga ctttaaaaat acatgtgatg atacatgtta
      421 tatgaattat caatgtaccc agtaatatgc tattttcatt atgtaaaaaa taacaggggg
      481 tgtgtagatg gagattgatg aaacttgttt gagtaactct tataaaagta tgaatgactt
      541 ttttgaggaa atggaactgg attcagaatt gctctatcaa ttttatcttg cttttcgagg
      601 gcaacagatt tcttttccaa tgaaaatgta cgatcgtgag ttagttagaa aaagaatcga
      661 aaacatgata gaacaggaaa aaactgtaga tatccgtcaa ttgacagaag tttatggttt
      721 ctctgcaaga tggattcaaa aagtaattaa acaaaaagaa aggagacgag tacatggcta
      781 agctgattgt attaggtggt ttaatttacg gtggatattg gttatatcaa tatatgcttg
      841 cgcatccgaa tatagataaa ggaaaagtaa ttaagacagt tggggtaatc atagttggac
      901 tcatagctct aactaagaaa aataatacta atagcccaaa aataatgaga acttatcgct
      961 gtagaggatg tggaagggaa atttctacta gttttaatcc atctgagagt cctcaaggaa
     1021 gagaccgctg ccatacgggc tatcgacatt attgggaaag aatcgattaa aagattacca
     1081 tttagatcaa ttaattgtct gatagaataa gtacgtgagg gagaaattga aagggggaaa
     1141 tataatgaaa aaatggctgt tattactaat aggaatggga attttattca ctggttgtac
     1201 atctgagaat acgaggacta aagcgactat agaaactgat acaacaattg agactaaaaa
     1261 aagtaaaacg caatcaactg aacaaactac aacagaaatg aagcaatctg tggaaacaag
     1321 tgcaagttca atcactgaat cttcttctga agaggttaag aatactttgt gggatacgaa
     1381 taaagcttcc aaattagaaa cttttgtcac acaatgggga aagacattag gtcaagaata
     1441 taaaagctac aatcttcaga ataatgtaag tctgtatggc actcctttac cacaagccgt
     1501 gattaatggc gattggaaaa tggcaatcaa tgaagcacca gttaccgtac aatggtcaga
     1561 agatggaact ggtc
//
LOCUS       DADGHT010000209         1569 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.217, whole genome shotgun sequence.
ACCESSION   DADGHT010000209 DADGHT010000000
VERSION     DADGHT010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.217"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            273..680
                     /locus_tag="JX887_002873"
     CDS             273..680
                     /locus_tag="JX887_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258790.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            694..1095
                     /locus_tag="JX887_002874"
     CDS             694..1095
                     /locus_tag="JX887_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258791.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1097..1468
                     /locus_tag="JX887_002875"
     CDS             1097..1468
                     /locus_tag="JX887_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258792.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
BASE COUNT          590 a          196 c          268 g          515 t
ORIGIN      
        1 tatagttgtt gatatagttg ctaatattgt tagctaattt gttagtaaaa ctgtatacga
       61 atttagatag taaaaaaaca gtttgttcct tatatagagg cacttttact actgattaaa
      121 tgtcagatat gcttacaaat atacttataa atatgcttac aaaattagct aatatttccg
      181 ttgacaaagc tttgttacta ttgttaaact aaattgacta gcaaaagtga aacataaatt
      241 tattaaataa atgtaaaaat taggagaaat caatgtctta tagagtacaa ttaataattt
      301 cagaagatgt agaaagtcag caatttggca ctaatgttat taataaagta attaatccag
      361 ctctttctat taatgcgcct ttaattccta ctgctttatc attttctgta acagctgtgg
      421 tgtctgagat agaggataca gaaaagataa aaatagtaga aattgaagtt ttaaacaaga
      481 atgaaaaaca aattttttct acgggtgaag tatcggtaag cttgcctcct caagttaacg
      541 atataaactt taatataaac gccagaaatg tcttggttga agaagcagga gagcattatg
      601 ctgttgttaa atttaatgga actgagattg gaaggcaaat ctttgatatc aaggtcaaca
      661 aaccagtgga aaaaaattaa ggagacgata cggatgcttg atatagtacc atcaaataca
      721 catcggagtg gtagcttaat aaattttgct gcgatttttg cttgcgcatc ggtaattcta
      781 gcatctccag ttgttgtgga tgcaagttct actccgaaaa ctaaaaatga taatcaactt
      841 gtaattacta caaaaaatga gattaacaca atttcaagta atgatggcaa aatttttgat
      901 gtgataaata cggttttaaa aagaaaagct gaaatcaata taaaatatga tgaagattta
      961 aacttgtatt tctttgttat caaaacaaca tctgaattgt tttcctcaga ttacgatgtt
     1021 ttggatactc tcgataatgt attatctgac tataaatata tggggaaatc tgtagtagca
     1081 actttggggg aataaaatgt ttgactttaa tgaatattta tctatttcca aacaaattga
     1141 atcagatgat aaatataatt ctaaagaatc ttatagaaga actgctgttt caagagcata
     1201 ctacagtgct tttaaaaaat ctgatgagta tttgaaagaa aattatgata ttatttataa
     1261 tggaagtagc ggaaaaggaa gccaccaaac cgtttggaat ttgttttcaa cagttaagga
     1321 attgaatacc ttaggaatac ataatagtgg gtatagaatg ttagagaaaa gaaaatgtgc
     1381 tgactatatt cctaatgaaa ccattacgaa aacagatatg gcgctgatga atcgagaagc
     1441 agaaaaaata ataaacaaac tcacctaatg aatttcaagc gagtttgttt gttatttttt
     1501 tatttaatct ttgtatcttt ctggatcaac gaaagtatac tttatatagt cataacgccg
     1561 atgatcgct
//
LOCUS       DADGHT010000210         1558 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.218, whole genome shotgun sequence.
ACCESSION   DADGHT010000210 DADGHT010000000
VERSION     DADGHT010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.218"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..841)
                     /locus_tag="JX887_002876"
     CDS             complement(<1..841)
                     /locus_tag="JX887_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAX1258793.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRI"
BASE COUNT          500 a          312 c          266 g          480 t
ORIGIN      
        1 ctattcttga gctggctgca gctagtgagt gtctttcatt tatccataag ataaagcttg
       61 gattcaataa ataaataaat gttttggtta aagctgtgac cagcaaatga ggaaccgtgc
      121 gagccagttg atctgccaat gcaaacattt ctttaggtga aggcgctggc gtgtctgcca
      181 acggatactc cagtcccaat gcttggtaac cgtgcatacc atagcagtgg tacggtagta
      241 attctaacgg tacgaaccga tcaagatctg ccacaaaaca agcaatcgtc agcagctcgg
      301 tcaggttcat attgatacct ggaaccacag gaactcgaat tcgcacttcg cagttaggat
      361 actcaattaa aaagcgacga atattcttca aaatttgttg gttatctaag ccggtccatt
      421 gtttgtggag cttgctggta aacattttta catccacaaa caatgtatcc acatagggag
      481 ctaccttttg gatttcatta taagcaccac aaaagctggt ttccagtacg gtattgattc
      541 caatgtattt cgatttttgc aaaatttctt tagcaaaatc cgcctgaacc agtgcctcgc
      601 ctccgctaat ggtcactccg ccatccgagt gaaagtaaaa aacagcatcc ttctcaatct
      661 catccattac ctcttcagcg gtcatggtct ggccaaatcc tttttcaatc tgcttgcttt
      721 gtgattcggg aatcgaacac caggcacagc gtaatgggca gccctttaaa taaacaacgg
      781 tccgtaaacc agcaccatca tgtagagaac cctgttctat tcttaatact gttccttcca
      841 tatagatttt tgaattacac actagtttaa actaaaacac acaaggaaaa acttaccatt
      901 taatcataaa attagctcat ataaatatac taggatgtaa aatagactgg tcaaaatctg
      961 gtcaaaaaag aggactaata caggtagtcc tcttttttgt tattttaata ttctaaatca
     1021 ttttttattg gtttattccc ttattcgatg tagactcaaa tcactatatc actagatatc
     1081 aaacggcgtc atacggaatc aaaaacatca aatttgacct gttaaatggt cattgaataa
     1141 cattcaaaat caataaaacg gagtcagaca cggagtcaaa aacgctgaga gtaaaaaata
     1201 tatacagcct tgtaggtaaa gtaccacagg gctgtatatt ttttatttca gattacctta
     1261 aatgattcca tttacttttt atctcatttt ttcctactag ttagtatcaa atactctcct
     1321 attttctcaa taaactattt ttggatacat ggtatctgaa acagctaaaa ccttgtcatt
     1381 acagcaaaaa atcacgttat ccagactgta gacaaagtcc attttatgga tgatgtctac
     1441 agtcttttct tttataatag atttatgaaa acgaatgcaa ggagtgatag ctatgatgtc
     1501 taaaaacaat acgaatggta gaaatcaatt tgcgatgctt acgattgatg atctagtt
//
LOCUS       DADGHT010000211         1546 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.219, whole genome shotgun sequence.
ACCESSION   DADGHT010000211 DADGHT010000000
VERSION     DADGHT010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.219"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..170)
                     /locus_tag="JX887_002877"
     CDS             complement(<1..170)
                     /locus_tag="JX887_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAX1258794.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAH"
     gene            complement(188..508)
                     /locus_tag="JX887_002878"
     CDS             complement(188..508)
                     /locus_tag="JX887_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1258795.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            807..>1546
                     /locus_tag="JX887_002879"
     CDS             807..>1546
                     /locus_tag="JX887_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAX1258796.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEG"
BASE COUNT          573 a          264 c          244 g          465 t
ORIGIN      
        1 aaatgtgcaa gttcatgaga taaatgaaag gcttctgcag tttcaccgta tagattttca
       61 ttcaaaaaaa tgattctggg ttttggatag tagaaaccag gctctttcat ctccatataa
      121 actactttca aattgtattc gctcaacatt tctttcaatt tcaaatacat acaaaccatc
      181 actccaacta ttcattttcc tctaaagctt tagcaattgc aatcgcttta cgcattgtct
      241 ccttagatat ttcttttcca tcaaaagaaa aaacagtatc gtcttctgat aaatccacat
      301 gtttaggggt ttctctttct tctctaccta gaaggtagtc tacagagaca tcgaaatagt
      361 cagcaatccg acttaattca tctgaattag gagtattatt tttccacttt gctagataac
      421 cgttagaata tccaaaatta atttctaact gccgtataga tatctttttc ctcttcgcca
      481 agtcttttat tatttcatag gtattcatcg ataaaacaac ctttctaaat gtttacaaaa
      541 aaagtttaga aaaatacgca gaaataattt gactaattct gagtaatgag ctatactata
      601 tcttgtaaac agatttaaca actaaaaaga caacaaaaaa cactattgat atgtaaatgc
      661 agaccgccaa gaaagcttta aaatcaatgt ttttatgtct tatttaatta tgctcttagt
      721 atagagtatt actcagatac tgtcaattga atttagaaaa aagttgttaa atttgtttac
      781 gaatataaaa gaaaggaatg agaaatatga acacaccgca aatttttaat ttcgaacaaa
      841 acgaagttcg gacaatttta gtaaatgatg aaccatattt tgtaggcaaa gacgttgcga
      901 gtgttttggg ttattcaaac actaaagatg ctttgtcgcg gcatgtagat ttggaagata
      961 agatggggtc gcgaatcacg acctcaggtc aatcaagaga gatgacaatc atcaacgaat
     1021 ctggtttgta cagtttaatc ttaaaatcaa aacttccctc tgccaaaaaa tttaaacgtt
     1081 gggtaacaag tgaagtgttg ccagcaatta gaaaacatgg aggttatcta actccagaaa
     1141 aagtagaaga agctttgctt aatccagata caatcattca attagcaact caactaaaag
     1201 aagaaagaac tggaagatta atcgcagaac aaaagattgc agagtacgaa cctaaaatct
     1261 cctatttaga tagcatatta tcttctacag attcagtaac aattagtcag attgcagcag
     1321 attatgggat gtctccacaa cagatgaata aattacttca taaactaggt attcagaaaa
     1381 aagtcggtaa ccaatggtta ttgtgcaaaa aacacatgaa ccaaggatac acaaaatctc
     1441 atacaactga gatcccgaaa gccgatggtg gcactaaaat tgtaatgaat accaaatgga
     1501 cacagaaagg gcgtctattt atctacgaat tactaaaaaa agaagg
//
LOCUS       DADGHT010000212         1500 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.220, whole genome shotgun sequence.
ACCESSION   DADGHT010000212 DADGHT010000000
VERSION     DADGHT010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.220"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1453
                     /locus_tag="JX887_002880"
     CDS             <1..1453
                     /locus_tag="JX887_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAX1258797.1"
                     /translation="DKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDTVANGG
                     LGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIVLALPF
                     GVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGALLAPL
                     IVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEERKGFIR
                     NLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVTAEEKP
                     RVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNPIFIFI
                     LTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPLWLLGS
                     FFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFYTPGTE
                     SAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          406 a          287 c          317 g          490 t
ORIGIN      
        1 agacaagggc ttcttcgggc agccgaaggg attgtcaact ttgttcttca ctgagatgtg
       61 ggaacgattt agttattacg gtatgcgtgc attacttatc tattatatgt acgatacagt
      121 tgccaacggg ggacttggat taccacgagc aacagcatta gctatcatgt cgatctacgg
      181 atctttgatc tacatgtcta gtatcgtcgg cggatgggta tctgaccgag tgttaggagc
      241 aaaacgcact gtattcttcg gtggagtttt cattatgctt ggccacatcg tcttggcttt
      301 accatttggt gtaagtacat tgtttgtttc gatggcattg attattatcg gaaccgcctt
      361 tttgaaacca aatgtttctg gcatggtcgg acatctttat tcaaagactg acttgcgaag
      421 agatgcagga ttttcgattt tttacatggg tgtcaactta ggggcattat tagcaccact
      481 aatcgttggt acaatcggtc aagaatataa ctatcattta gggttctctt tagctgctat
      541 tgggatgttc tttggattat tacaatacat catccaagga cgcaagacat tagacggagt
      601 gggtacaaca ccgccgaatc ctttgacaac tgaagaacgt aaaggattca tccgtaactt
      661 gatcatcgca cttgttgtta tcgctgcagt attcggcggg gcacaactaa ctggtcatct
      721 gacaattgac ttttttgtca atacaatcag tgtattgggg attatcttac cgttgtatta
      781 ctttatcaaa atgctgactt caaaagatgt aactgctgaa gaaaaaccaa gagtatgggc
      841 ttatatccca ttattccttg cagcaatcat tttctggtca ttacaagaac aaggttcatc
      901 tatcttagct ttatttgcta gtgaacgtac acaatctacg ctatttggtg taacgatcca
      961 agcaagctgg tatcaatcat tgaatccaat tttcatcttt attctgacac cagtattcgt
     1021 aacgatgtgg acgaaacttg gtgaacgtca accatctaca gtagtgaaat tctctcttgg
     1081 acttttattt gcaggattat cgtacttgct attgatgttg ccgggtatgc tttatggtac
     1141 aagtggaaaa gtaagtccat tgtggttgtt gggaagtttc ttcatcgtgg ttattgctga
     1201 attgtgtctt tcaccagttg gtttgtctgt gacaacaaaa ttagcaccac gagcatttga
     1261 atcacaaaca atcgctattt ggttcttagc tgatgcttct tcacaagcaa tcaatgcaca
     1321 aattgcacgc ttctacacac cgggaacaga atctgcttac ttcggtatta tcggtgcagt
     1381 agcaatcgtc ggtggtatct tgctatttac tgtgaaagaa ccaatcaaaa aactaatggg
     1441 ctctattcat taatcaatga acataaaaac aggaattgct tatttgcagc agttcctgtt
//
LOCUS       DADGHT010000213         1499 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.221, whole genome shotgun sequence.
ACCESSION   DADGHT010000213 DADGHT010000000
VERSION     DADGHT010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1499
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.221"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            64..1233
                     /locus_tag="JX887_002881"
     CDS             64..1233
                     /locus_tag="JX887_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAX1258798.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          532 a          249 c          246 g          472 t
ORIGIN      
        1 aaaaaaaagt ccattctgta aaattaaagt taccacacag aaattttata ggaggacttt
       61 ctcatgacta aatttactat agaaattatg caaacactac tcaataaagg ggatttagat
      121 gaattatttc aggatcattt agagcgagcg attaattcac ttctacaagc agagctaact
      181 gcttttttag attacgaaaa atatgatcga aatggattca attcaggaaa ttcccgtaac
      241 gggaattatt cacgtacatt taaaacagaa tatggcgagt tgaatttaac tattcctaga
      301 gatcggaatg gcgaattttc tcaacaaaca ctaccagcat ataagcgaac caatgattca
      361 ttagaaacga ccattatcca attatttcaa aaaggcatta ctatggctga aatctccaaa
      421 ttaattgaaa aaatgtatgg tcaccactat acgccacaaa caatctccaa catgagtaaa
      481 ttggtggctg aagatgtttt agcttttaaa gaaagaacgt tagaagccaa ttattccgtt
      541 atatttatgg atgcgacgca tatccctgtg aagcgacaga ctgtttcgaa ggaagcagtg
      601 tatattacga ttggtattcg tttggatgga accaaagaag ttcttgggtt tactattgcc
      661 ccaactgagt ctgcttatat ttggaaagaa gttcttcaag atcttagaaa acgtgggtta
      721 gaagaagttt tattagtagt gacagacgga ttaagctgta ttgaagaaag tatccatagt
      781 gtgtatccga atgcccaatt tcaacaatgt tgtgtgcatg tatctagaaa tatcgctcat
      841 aaagttcgtg ttcgaggtcg aaaagaaatt tgtgaggatt tcaaattggt ttaccaagcg
      901 aattcaaaag aagaggcatt ggatcacatc gactttatga ctaggaaatg gaaaaagcag
      961 tatccaagag tcgtcaattt actcttgaat cctgccctat taacctttta taatttccct
     1021 cacgccatca gacgaacaat ttattcgacg aacctgattg aaggctttaa taagcagcta
     1081 aaacgatata ctcgaagaaa agaacaattc cctaatgaag aatctctaga gagattcttc
     1141 atttctcaat ttaatcaata taaccaaaaa tttttaggta gaattcacaa gggatttaaa
     1201 gaaattcagg atacattaga gtcgatgatt taactgtaat taacagaatg gattttccat
     1261 ttacacataa ttcttgacgc taccataatc taaataacca tcatattcat ctactactta
     1321 tataattgag ttttattaaa ctttttaagt ttctattcta tcaaatattt aaacaatctc
     1381 tgcatccgaa aagactacct cgtatagttt tactaacaat atttttatta gcgtgttcaa
     1441 atcctgattt cttgtatcaa ttattttctg ttcactttca ataagaaaaa agtctttac
//
LOCUS       DADGHT010000214         1480 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.222, whole genome shotgun sequence.
ACCESSION   DADGHT010000214 DADGHT010000000
VERSION     DADGHT010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.222"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            64..972
                     /locus_tag="JX887_002882"
     CDS             64..972
                     /locus_tag="JX887_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAX1258799.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..>1480
                     /locus_tag="JX887_002883"
     CDS             972..>1480
                     /locus_tag="JX887_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258800.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGV"
BASE COUNT          529 a          197 c          316 g          438 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt
//
LOCUS       DADGHT010000215         1457 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.223, whole genome shotgun sequence.
ACCESSION   DADGHT010000215 DADGHT010000000
VERSION     DADGHT010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.223"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1014..1304)
                     /locus_tag="JX887_002884"
     CDS             complement(1014..1304)
                     /locus_tag="JX887_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258801.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT          465 a          287 c          203 g          502 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcag
//
LOCUS       DADGHT010000216         1453 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.224, whole genome shotgun sequence.
ACCESSION   DADGHT010000216 DADGHT010000000
VERSION     DADGHT010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.224"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            110..>1453
                     /locus_tag="JX887_002885"
     CDS             110..>1453
                     /locus_tag="JX887_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAX1258802.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKG"
BASE COUNT          520 a          175 c          300 g          458 t
ORIGIN      
        1 aagaactgat gttttattta aatgtttatc gggagattat gtagatattg aacaaaaata
       61 tatagatact ttttggaaaa atcttactaa taagtagagg agaaagaaaa tgactataaa
      121 agtagattta cgaaaaaaac catataattt agatgaagat gctatttctt ggattgaaga
      181 gacgattgat tctatgactt tggaagaaaa aataggtcaa ttgtttgtta atatgggatc
      241 tagtcgtgat aaaaattact tgagtaatat ggtcaatcag taccatattg gagctgtacg
      301 atataatcca ggaactgctg atgaggtata tgatcaaaac tatatcttac aaacagaaag
      361 taaaattcct ctattaattg ctgctaatac ggaagcaggt ggtaacggag cttgtacaga
      421 tggtactgaa gttggtgtag aagtaaaaat tggtgcaaca aatgatgcga aatatgctta
      481 tgaattaggg agagtttctg ggattgaagc atcggctatt ggatgtaact ggagttttgc
      541 tcctattgta gatattaata gaaattggag aaatcctatc atttctagtc gatcttttgg
      601 acaaaaccct gataaagttt tagaacttag tttagcttat atgaaaggta ttcaggagag
      661 tggaattttg cctgcagcta aacatttccc tggtgacggt attgacgaac gagatcagca
      721 tctatctttt agtattaata gtttaggtac ggaagaatgg gataattctt ttggaaaagt
      781 atactcaggc ttaatagaag ctggattacc ttcaattatg gcaggtcata tccatatgcc
      841 agcttattca aaacatttta atcctgatct gaaagatgaa gatttacttc ctgcaacttt
      901 atcaaaagaa ttaatcactg acttacttag aggaaaactc ggatttaatg gattagtagt
      961 tactgatgct agtcatatgt taggaatgac tggggcaatg aaacgatcag aattattgcc
     1021 cacttctatt gcagctggat gtgatctatt tctatttttt aatgatccag atgaagactt
     1081 taattatatg atggaaggct atcgtaaagg aattatcact gatgatcggt tattagatgc
     1141 tttaaaaaga attttagggt taaaagctaa attgggatta cacaaaaaag caaaagaaca
     1201 aattttatta cctaagcaag aagctctgga aaaaattggt ttaattgaaa ataaatcaat
     1261 ttttaaagag gtggctgacc aagcaattac attagttaaa gataaacaag atatttggcc
     1321 tattgtacca gaaaaatata aaaggatttt actagtagat gtacatgggg taaaaggtgg
     1381 gtttggtgaa gtagttgctg gaaatagacc tcaagccatt gatttattga aacagatttt
     1441 gtcagcaaaa gga
//
LOCUS       DADGHT010000217         1434 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.225, whole genome shotgun sequence.
ACCESSION   DADGHT010000217 DADGHT010000000
VERSION     DADGHT010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.225"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..945
                     /locus_tag="JX887_002886"
     CDS             <1..945
                     /locus_tag="JX887_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1258803.1"
                     /translation="INDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNVAANMKNNY
                     NGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKALFEKNYRA
                     YIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYLSQMGVSKE
                     KLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGEIENANLHV
                     AGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYHVSFNMRNF
                     PSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
     gene            1135..1208
                     /locus_tag="JX887_002887"
     tRNA            1135..1208
                     /locus_tag="JX887_002887"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1169..1171,aa:Ile,seq:cat)
BASE COUNT          475 a          241 c          288 g          430 t
ORIGIN      
        1 attaatgacg agtataattt agcgccgaat caaggagact ccagattagc aattcctaac
       61 aaaattattt tgcacgaaac tggaatagat gcaccagcaa gaaacgtagc cgccaacatg
      121 aaaaataatt ataacggaag caattcttat actacagatg ttattggtga cggtgggatt
      181 gtttaccgtg tgggtgagca aggatatgtt tcgtggggag ctggtaacgc taatccttat
      241 gcgcctgtac agattgaatt acagcgcaca tatgataaag cattgtttga aaaaaactat
      301 cgagcttata ttgaatatac aagagatagt gcaaaaaaat atggaattcc attgactctt
      361 gatcaaggaa cttctttatt tacaaaagga atcatttctc atttgtgggt gacaaattat
      421 gtttggggga accacacaga tccatatggt tacttatcgc aaatgggagt tagcaaagaa
      481 aagcttgctt atgatttagc tcatggattt accgatgaaa atccaacaac ttctgaaaac
      541 aagcctgtca ttgatccaac acgagctggt gcagctaatc ctacgctgac agatggaaca
      601 aatcacgccc acattgatca gtttggggaa atcgaaaacg caaacttgca tgtggctgga
      661 tggcacattg ctaactataa atacgagtat attttcatta tggactacaa tactgggaaa
      721 gaattagctc gagtaagagc tgatggaatt tatagaccag atgtaaacca agcttataat
      781 acttctggaa atgttggtta tcatgtatct ttcaatatgc gtaattttcc tagtaagaaa
      841 gtctatgtaa tgatgcgggc aacgaatgat ccagagggaa acactaaagg cggtgcgcaa
      901 gatttccatg acaaacgttg gtatttaaat attcctaaac gataaaaata gctcctcgtt
      961 gaggagcagt acataactat attgacaact ataaaaatta ttcgataaaa tagtgatgtt
     1021 atcgcatatc ttcactatca cccataaata gtcacactcc aagctatgcg ataacaggtt
     1081 tgttgccaca cattctactg gttgattgtt tatggcttta tgtggcaaca accagtaccc
     1141 ttagctcagt tggtcagagc agacggctca taaccgtccg gtcgtaggtt cgagtcctac
     1201 agggtacatt aacgtagcca tttgaatcgt tctgtgttag aatttttttg aagagtatta
     1261 tacaagctaa agcttttctt cattgccact caaatgagtg gcttttttat gtatcctttt
     1321 atggattaat gaaaggatgt ttcacatagt tatacttctg tatatttgaa aagttttact
     1381 ttgattttta aatagaaaga catttgggtt aaattgtgag ataataataa agaa
//
LOCUS       DADGHT010000218         1426 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.226, whole genome shotgun sequence.
ACCESSION   DADGHT010000218 DADGHT010000000
VERSION     DADGHT010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1426
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.226"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            249..>1426
                     /locus_tag="JX887_002888"
     CDS             249..>1426
                     /locus_tag="JX887_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HAX1258804.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     "
BASE COUNT          518 a          179 c          270 g          459 t
ORIGIN      
        1 cttagcatta aaacgaattg aattagactt agatgatggt gtaattgtca attatgataa
       61 gttgcagcgt gatcctaaaa ccggcgagaa attccaaatt tttgcaaaag gggtcaaaga
      121 accaaaaaaa tagttatcta agaaagttgt tttctaacaa ctttcttttt tattcttaaa
      181 ttgcgtgcga aattatccaa attatgtcaa tataaggggt atagaaagag aacgattagg
      241 tgagattgat gacagatata aatacgcaac aaattgaaga aaaattaaat caacgttttc
      301 ctaattatgg atgtaggaaa atcatttttt ggtttgattc aaatcaggat tttcttgaag
      361 aaattgactc attggtcatt caaaatgcaa aaatctatcg attagaaaag gacgcacaat
      421 ttaaaactaa gcgtttattg gaatatgaag atcccgaaac taactattta atctatgcgc
      481 catttcctcg ttgggatgat aaagatgaag ataatcattt gttgagtgta ttgaattatt
      541 cagaggaatt tagtgcagac cgcttagcga ttatcatgaa tgaattggct attccactta
      601 gatttcatca gacagttaaa cagtatcgta atttctttaa tgcaaaggat cgcatgagaa
      661 gttttggtga atttagtacg catatgacaa ttaataaatc agaaacgatt gaattaatga
      721 taatggctgt tttgttgaaa tcgaaaagta ttcgattaaa tgatttactg cgtgtagttc
      781 taaaaagctt tacagaaagt agggagaatc ctttaaggga acttgataag tatcagttaa
      841 cagctaaatt ttgggaattt attcaaatga aatttggctt tacggatagc cagccaacat
      901 tggaaaagct gacgatgtgt ctttatttga actattttta ttatcaaatt gatcaagaga
      961 tgccgaagaa gttcaaagga tttgaaatac tacatttgaa agcaaacatt attactttca
     1021 tggatcagtt tatgaatgat acacgttaca tggaaagctt tgaacagcta tctaaaaaag
     1081 tatatcaggc tattgatggt gatggattat tagacagtat agaaattgat gatctaattg
     1141 aagcagacgt attttctgag attcatgcaa aaatattaat gttttatgca gaacgattaa
     1201 aggcttctga cactacaacg aaaattgcag gacaaacaat ttttgatagt ttaaagcagc
     1261 gcgaaaaaat gcatttcgca tcggattata tttatgagta tcaattattg aaacatgctt
     1321 attatcttgt ggataaaaac agattgtgct tgccgatgaa catggataat ttgctaactc
     1381 aatatgagaa ggaaatgtat tgggttgata cgcattatcg gaaatt
//
LOCUS       DADGHT010000219         1424 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.227, whole genome shotgun sequence.
ACCESSION   DADGHT010000219 DADGHT010000000
VERSION     DADGHT010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.227"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(150..1337)
                     /locus_tag="JX887_002889"
     CDS             complement(150..1337)
                     /locus_tag="JX887_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAX1258805.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DADGHT010000220         1396 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.228, whole genome shotgun sequence.
ACCESSION   DADGHT010000220 DADGHT010000000
VERSION     DADGHT010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.228"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..365
                     /locus_tag="JX887_002890"
     CDS             <1..365
                     /locus_tag="JX887_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HAX1258806.1"
                     /translation="SFDRQTAEICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGS
                     AFGPSIVKAYQAPLPHVNIMPTGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEE
                     VSRVASKYIDKFYEIKNY"
     gene            485..>1396
                     /locus_tag="JX887_002891"
     CDS             485..>1396
                     /locus_tag="JX887_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1258807.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKK"
BASE COUNT          458 a          177 c          270 g          491 t
ORIGIN      
        1 catcttttga tcgacaaaca gctgagattt gtaatttata tcaaattcct tatttaccag
       61 gttgtatgac aattactgag ataaaggagg cacttactgc tggcgtagat atcattaaac
      121 tattcccagg ttctgctttt ggtccatcca ttgtaaaagc ctatcaagct ccattaccac
      181 acgtaaatat aatgcctact ggcggagtaa gtatagagaa cttagaagat tggtttgaag
      241 taggagttgt tgcagttggt gtaggtggga atttattggc ttctgttgaa aaaggtgatt
      301 ttgaagaagt aagtcgagta gctagtaaat atatagataa gttttatgag ataaagaatt
      361 attaggagaa aaaacaaata atactctgaa atgtaaaaaa taaatactga ctctttacgc
      421 ttcagagtat agtacgtact ttcatcagaa tgaaaacgct taacaacaga agggagagaa
      481 ttgtatggaa agaaaatttg gtataagaga caaaatagga tatatgtttg gagattttgg
      541 aaacgatttt actttcattt ttgctagttc ttttttaatg atcttttata caaaagtatt
      601 ggggataagc ggagctgccg ttggaacatt atttttagta gcaagattta tcgatgcagt
      661 tactgatgta actatggggc gtattgttga tagatcgaaa gcaactaagc agggtaagtt
      721 taaaccgtgg attttaagaa tgagtggtcc agtcgcttta gcaagttttt taatgtatca
      781 aacttctatg atttcagctt ctatgagcgt taaggtagta tacatgtatg ttacgtatat
      841 attatggggg agtatttttt acacatctat aaatattcct tatggatcaa tggcatcagc
      901 tattacttct attacagaag aaagaacaat gctatcgaca ttccgaaatg ttggagctac
      961 tttagcaagt ttggtcattg gtgtattaac accattattt atttatacaa gagatgattc
     1021 aggcgctcaa atagttcgtg gtggatcaac ttttacaatt gttgcgggaa tattttcgat
     1081 atgtgcactt atttgttatt taatatgtta taaactaact actgaacgag taagaattga
     1141 ccaatctcaa tacaaagttt cattgttaaa atctttaaaa gggttagtta aaaatagggc
     1201 attactttct ataattggtg cggctatttt cttactcctt gctcaattat taattatgag
     1261 tatgaataat tatgtatttc ctgattacta taatgatgca cagggaatag ttttaatgaa
     1321 ttttatcaat cctattttgg ttttaatagt tgtttcgcct ttaactttgt ttttaagtaa
     1381 aaaatatgga aaaaaa
//
LOCUS       DADGHT010000221         1385 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.229, whole genome shotgun sequence.
ACCESSION   DADGHT010000221 DADGHT010000000
VERSION     DADGHT010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.229"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            102..>1385
                     /locus_tag="JX887_002892"
     CDS             102..>1385
                     /locus_tag="JX887_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAX1258808.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTF"
BASE COUNT          436 a          274 c          263 g          412 t
ORIGIN      
        1 ggtgaacttc accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc
       61 tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat actcagctta
      121 tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta
      181 aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag
      241 aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa
      301 ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac
      361 aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa
      421 aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata
      481 cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca
      541 tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct
      601 ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatggacg
      661 gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat ttagaacgct
      721 atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt attgatatgt
      781 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
      841 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      901 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      961 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
     1021 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
     1081 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
     1141 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
     1201 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca
     1261 gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta aaacgcaatg
     1321 cgtacggctt tcgcaacttt tacaatttca aactacgaat tatgattcgt catggcaaaa
     1381 cattt
//
LOCUS       DADGHT010000222         1358 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.230, whole genome shotgun sequence.
ACCESSION   DADGHT010000222 DADGHT010000000
VERSION     DADGHT010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.230"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..608
                     /locus_tag="JX887_002893"
     CDS             <1..608
                     /locus_tag="JX887_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258809.1"
                     /translation="ENQLFAGDVLEIVLNDQAGEAAAKGVQNKPSTNDEIGNHNPSDT
                     PVVYHDAPPFAPATKIVVEGGLSFLAPSKLDCGQIKATGLTQEAFGQMDIQEKLWIYD
                     QRETKSPWILTIKLSQPFTTDAGFSMQDVLYFKKAEEYQLVNEEELEIVRGQNSTNVQ
                     TDYSEYLNNGRAFKLVLTKENQIAGNYSAEMTWTLADAPTE"
     gene            628..>1358
                     /locus_tag="JX887_002894"
     CDS             628..>1358
                     /locus_tag="JX887_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HAX1258810.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKK"
BASE COUNT          494 a          242 c          279 g          343 t
ORIGIN      
        1 cagaaaatca actttttgca ggagatgtat tagaaattgt attaaacgac caagcaggag
       61 aagctgctgc taagggtgtg cagaacaagc caagtaccaa cgatgaaatt gggaatcaca
      121 atccaagtga tacgccagtt gtttatcatg atgccccgcc ttttgcacct gctacgaaga
      181 ttgtagtaga aggtggtctc tcatttcttg ccccttccaa actcgattgt ggtcagatca
      241 aagcaactgg gttgacgcaa gaagcatttg gccaaatgga tatacaggaa aaattatgga
      301 tttatgatca gcgagaaaca aaaagtccat ggatcttaac gataaaatta tctcagcctt
      361 tcacaaccga tgcaggattt tctatgcagg atgtcctata tttcaagaaa gctgaggagt
      421 atcaattagt gaatgaagaa gaactggaaa ttgtcagagg acaaaattca acgaatgtgc
      481 aaacagatta ttcagaatat ttaaataatg gtcgggcgtt taaacttgtc ttaaccaaag
      541 aaaatcagat agctggtaat tactcagcag agatgacatg gacattagca gatgcgccga
      601 cagaataaag atcaaggaga atgattgatg aatcgaatat ggaataaaag tcatcgaaac
      661 aactgctctt tacttctgat ccttctcctt ggattcatcc tttggcagac acctgtccat
      721 gcctccgaat tcaattttgc ggtagatttt gaattaccgg ctaatcagat tgataagaac
      781 aaaacatata taaatgtaag gatggagcct gggaaaacac aggaaatccc ctacacggtc
      841 tttaaccgaa cagataaatc agtaacagtt gagacattga tccactccgc tacgacgaat
      901 tcaaacggtg tgatcgaata tggagaatca aaaagtaaat ttgatgaaac attaagttat
      961 gatatgaaaa acttagcaaa aacagtggga gaaataactg tccctcctca aagtgcggtc
     1021 actgagacac tttcactgaa agctccagaa aaagagctgg ctggtgtggt cgcaggagga
     1081 atcacgtttc aagaaaaaaa agagaacgtt tctaacaaaa gtacagttgg tgtcgtcaat
     1141 cagttttctc aagtgaaagc aatcttgatt cgaaatagcg aaaaagagtc ttccccaaat
     1201 ttgaaattaa aaaaaactta tgcggatcaa agcgatggaa gaaatgtgat taaggcgaat
     1261 cttcaaaatc caaatgcttc ttatatgttc ggcttgacta catcggttga aatctacaaa
     1321 aaagaaacaa aagagcctta tctttcaata aaaaaaga
//
LOCUS       DADGHT010000223         1300 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.231, whole genome shotgun sequence.
ACCESSION   DADGHT010000223 DADGHT010000000
VERSION     DADGHT010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.231"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            25..1251
                     /locus_tag="JX887_002895"
     CDS             25..1251
                     /locus_tag="JX887_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAX1258811.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT          476 a          202 c          283 g          339 t
ORIGIN      
        1 gaaaatgtga aacagaggtg tattatgaag cgatggcaaa aagttctatt aaccttgtta
       61 ggggtattcg ttttgctgat tgccggatta tcagcatacg gaatcagatt tatgggagaa
      121 gcgagccaaa cagtaaacaa aatttctaaa aactctaatc gaatatcctc caaacgttct
      181 gagagagtaa gcattgatga caaagaacct ttttcggttt tgctattagg tttagatacc
      241 ggtggattag gaagaacgga acaaggacgt tctgatacga tgatggtagt aacagttaat
      301 ccgaaacaaa aaaaatcaac gatcatcagt ttggaccgag atatttatac gaatatcgta
      361 ggttatggaa cggtagataa attaaatcat gcctacgcat ttggtggtgt cgaaatggcc
      421 atggattcaa ttgagcaact gctcgatatt cctattgatc attatgtaac gatcaatttg
      481 gatggcatgg aagatttgat caatgcggtc ggtggcatca aagtgaataa taaaattgac
      541 tttactttgg atggtgtcca tgtaccagta ggtgaacaaa cattgaatgg agaaaaaggt
      601 ttagcctatt ctcgaatgcg acacgaagat ccagaaggcg atatcggtcg acaacgtcgt
      661 cagcgggaag tagtgacgaa aatcgtcaat aaagttttaa gtttagatgg cgtaagcaat
      721 tatagaaaaa ttttaaaagc agttgagaac aatgtgacga cggacttaga ttgggatgac
      781 atgcttgatg tagcgacgaa ctacaccccg gcgtttgaaa caatcaaaca agaccagttg
      841 caaggcgaag gacaaatgat caatgatatc tactatcaaa ttttaggaaa aaatgatctt
      901 ctttcgatcc aaaatgaact gaagaaacaa ttaaatataa aaacaagcga tacattacct
      961 aatttgaaaa atgagaatgc ttcaatgatg ttctttgatg attcggaaga tggcgattcg
     1021 acaaacggtg atggatcgaa tagtgaaggg tacaccgatt attcttccta ttcagaaaac
     1081 acatatgatc agtaccaaga tccgaatacc tattatcagc aaacagaaga tacaagtcag
     1141 tactatacac caagtcaaga tactcaaagt tatgatcctt acgctggaca ggaacaaaat
     1201 ggttatggtt atgaccagaa taatgagtat ggaacaacaa gtgggtacta gaaaaaaata
     1261 gtttggttaa taaagagtgc cacctaaatt agacaaaaaa
//
LOCUS       DADGHT010000224         1293 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.232, whole genome shotgun sequence.
ACCESSION   DADGHT010000224 DADGHT010000000
VERSION     DADGHT010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.232"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1104)
                     /locus_tag="JX887_002896"
     rRNA            complement(<1..1104)
                     /locus_tag="JX887_002896"
                     /product="23S ribosomal RNA"
BASE COUNT          287 a          364 c          247 g          395 t
ORIGIN      
        1 cctagttgtc tgtgcaaccc cacatccttt tccacttaac atatattttg ggaccttagc
       61 tggtggtctg ggctgtttcc ctttcgacta tggatcttat cactcacagt ctgactcccg
      121 gatatgaatg aatggcattc ggagtttatc tgaattcggt aacccgagat gggcccctag
      181 tccaaacagt gctctacctc catcattctc aattccgagg ctagccctaa agctatttcg
      241 gagagaacca gctatctcca agttcgtttg gaatttctcc gctacccaca cctcatcccc
      301 gcacttttca acgtacgtgg gttcggtcct ccagtgcgtt ttaccgcacc ttcaacctgg
      361 acatgggtag atcacatggt ttcgggtcta cgactacata ctcaaacgcc ctattcagac
      421 tcgctttcgc tgcggctccg tctcttcaac ttaacctcgc atgcaatcgt aactcgccgg
      481 ttcattctac aaaaggcacg ccatcaccca ttaacgggct ttgacttgtt gtaggcacac
      541 ggtttcaggt tctatttcac tccccttccg gggtgctttt cacctttccc tcacggtact
      601 ggttcactat cggtcactag ggagtattta gccttgggag atggtcctcc cggattccga
      661 cggaatttct cgtgttccgc cgtactcagg atcctcctag gtgtcttcca catttcgtct
      721 acggggtttt taccctcttt gactgacttt tccaagtcat tcgactatct gaaagaacta
      781 ccatattgga gtcctacaac cccaacaagc aagcttgctg gtttgggctt ttcccgtttc
      841 gctcgccgct actcagggaa tcgaattttc tttctcttcc tgcaggtact tagatgtttc
      901 agttctctgc gtctacctcg aatgtgctat gtattcacac aatcgtaaca tcctattaaa
      961 gatgttgggt tcccccattc ggaaatctct ggatcatagc ttacgtacag ctccccaaag
     1021 catatcggtg ttagtcccgt ccttcatcgg ctcctagtgc caaggcatcc accgtgcgcc
     1081 ccttattcac ttaaccttat caaccttacg gttgggtttt gatccttctt ctagcgatag
     1141 aagttagatc aagaaaataa gcaattgaac ttattaaaaa actctatcca gctcacaaat
     1201 cagcctgtac ggcaaaaaga tcgatcgtct cataaaatca aagattttat ggccgtccgc
     1261 ctattttgct tcaggctaaa caatttgttc agc
//
LOCUS       DADGHT010000225         1276 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.233, whole genome shotgun sequence.
ACCESSION   DADGHT010000225 DADGHT010000000
VERSION     DADGHT010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.233"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            35..532
                     /locus_tag="JX887_002897"
     CDS             35..532
                     /locus_tag="JX887_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAX1258812.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
     gene            complement(569..1252)
                     /locus_tag="JX887_002898"
     CDS             complement(569..1252)
                     /locus_tag="JX887_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258813.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIK
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
BASE COUNT          444 a          216 c          224 g          392 t
ORIGIN      
        1 atttatagta tactatgtca aaaggaggag ttagatgaac aatcaaatca cactagcgta
       61 tttagattat gatgatctag atgctttaca agttgtaagt gttgtcagtt tttatgaatc
      121 gtttatcgat ggcgcagatc cacttgatat gcaaggatat ttacagacac aattgacaac
      181 tgaaatattg gcagtagaat tggcacagtc aaccagtaaa tttattggta ttaaggatca
      241 tcaaatactc attggttata tgaaagtcaa tgatgaaaaa gatgctatag agattcaacg
      301 gctctatctg ctcaaagatt atcaaaacaa agggttaggg caacggttac tcgatgaagc
      361 gaatcgttat gctaaaacga aacaaaaacg ttatttacgt ttgactgttt atgaaaaaaa
      421 tcatgcaggt attcgttttt atgaacgtca tggatttaaa aaaatcggga tcaaacattt
      481 tcctttagga aaacaagatc gtatttgtcc gattttagaa aaagaaatct aaaaaaacgt
      541 cctcactttt gatgctgagg acgttttttt agactggtaa tggaaccata attcgctttc
      601 ctttttgata aatcgctaat tccgtcacac catttgcttt taacagagca aaaagatcat
      661 cgaaatggaa acggaaatgt tcaaggtaat gcccatctga tccaacacta aacaaggtac
      721 caccacgtga aagatataaa tcgatgacat attcatataa cgctaaattg tcatacaagt
      781 aagcgctctt agcatttaat tcgaatgcca atttattttt gattacttga tctagaatcg
      841 gtaaaaactg cgcttcatat tgtttaaatt cagcaacgga tagaccaaat acccgaaaac
      901 catagtcaaa atgagcaaag acatctgctt ctataacaac tagtgcttct gaaagttgtg
      961 caaaatactg aggaatcaca atagcaggat ccatatcttt gacttcgtca tctaaataat
     1021 caaattgccc attatgatgc acactgagta attttaaatc gtaatcttta tcggctaaat
     1081 agtcgatgat ccgatccttt tcagaagcga tgtaaccgat tttgatgcct tttaaaacac
     1141 gattgccaaa acgcttattt aagctatcga ttgtttgact gtacatttca taatcgggga
     1201 tatcatcgac tttagtaaca ggattggcta agtcaaaatg ttcagttgtc acgacgtaac
     1261 catcgtagtt tgttaa
//
LOCUS       DADGHT010000226         1246 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.234, whole genome shotgun sequence.
ACCESSION   DADGHT010000226 DADGHT010000000
VERSION     DADGHT010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.234"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            200..742
                     /locus_tag="JX887_002899"
     CDS             200..742
                     /locus_tag="JX887_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258814.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            832..>1246
                     /locus_tag="JX887_002900"
     CDS             832..>1246
                     /locus_tag="JX887_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAX1258815.1"
                     /translation="MDELKRTEIQIIDKKERPKNGFVLSEKTDLENTEAFNKESVKDL
                     RKLPTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIV
                     GVVTDPVDDNGENKEAIEKSKLIHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DADGHT010000227         1226 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.235, whole genome shotgun sequence.
ACCESSION   DADGHT010000227 DADGHT010000000
VERSION     DADGHT010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.235"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..656)
                     /locus_tag="JX887_002901"
     CDS             complement(<1..656)
                     /locus_tag="JX887_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAX1258816.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     "
     gene            complement(656..>1226)
                     /locus_tag="JX887_002902"
     CDS             complement(656..>1226)
                     /locus_tag="JX887_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAX1258817.1"
                     /translation="KISYQYHVGQYLPDWHPWEDYRNFFVSNKKTNGCREIFAIELPW
                     IIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETGIVGTLSVDVVSRVAKRNLTI
                     IGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHDNNYSHTIIEDAYLEEIKEFF
                     TLLEKKMEPQYTFEKDKYIINLINDIEVN"
BASE COUNT          419 a          211 c          135 g          461 t
ORIGIN      
        1 atttctataa ttttatcatc gtatctcaat atatatgttg ctaaatcatt actgttaatt
       61 tcaagattcg aatatttacc aaactgtttt tttactgatt tagggaaacc aaataggttt
      121 ataatataat ccaattcatg tatacagtct aattctactc ctccccccat agatttaaag
      181 gcagaataat tatttctata atcagtacct tttctccaat caggaagata agtagaacaa
      241 atagctctta cagaatatac ttttttactt tgaatactat tacgaacaac ttccatgata
      301 tttttatacc tcagtggagc agcaacataa atatttttgt aatcataatt atattgagta
      361 agatcaatac tctcagaaaa agcaggtttt tctaaaaata tgtaatcaac tttttcaaca
      421 attacattta gtgtttccag atgcttaaaa gtcggatttg taataaaagc tatatcataa
      481 tgtgtatcca aatcgtctct attttgaata tacgttattt cttcaaactc tttttttcca
      541 ctgctactat aagctgttat atcaaaatta atagaattct tttttccata gcttattaga
      601 ttttttagat gtctctttcc aattgaccct aacccaaaaa aaattacttt catcattaat
      661 ttacctcaat gtcgttaatt aagttaataa tatacttatc tttttcaaaa gtatattggg
      721 gttccatttt cttttccaaa agcgtgaaaa attctttaat ctcctctaaa tatgcatctt
      781 caataatagt atgtgaataa ttattatcat gcataacctc atcgtacaat tgaatatctg
      841 tcatactaga agtttcttca ttccatgaaa atagagaatc cgggttacct tcccattcta
      901 ttaaaatctt ttcaccaatt atagttaaat ttcttttagc tactcttgaa acaacatcta
      961 cacttaaagt tccaactata ccagtttcat gctcaataat aagagtgaaa ctgtccgaat
     1021 aatcaatatc aagattggat aatttctggg tcattacagt aaacgattta actttcccaa
     1081 atgtatctat aatccaaggt aattcaatag cgaatatttc tctacaccca ttagtttttt
     1141 tgtttgaaac aaaaaaattg cgataatctt cccaaggatg ccagtcgggt aaatactgtc
     1201 ctacatggta ttgataagaa attttt
//
LOCUS       DADGHT010000228         1215 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.236, whole genome shotgun sequence.
ACCESSION   DADGHT010000228 DADGHT010000000
VERSION     DADGHT010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.236"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            414..947
                     /locus_tag="JX887_002903"
     CDS             414..947
                     /locus_tag="JX887_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAX1258818.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT          389 a          226 c          225 g          375 t
ORIGIN      
        1 cttattaccg cagatgcaag cttttgaaca ccgtttattg agaagttgtg aaatcagcgt
       61 cctgacctga gtattagaga aacaaatggc aaaatagttc ctcatatttt gctatttttt
      121 gagctaatac cgagggtcag ctgattgaac accgtttagt ggagaagttg tgaaaaagtc
      181 gcctactttc gagtcgtaag aaattttttt gaaaatggtt cctcacaact ttgcataaat
      241 ttgacttaat accgagaagt catgatcccc atctaactcc aaatcacaag gaatgagttc
      301 aaaaactagc ttttctcaac aaatattaca taaaaaattc tatgtttttt gttaaattta
      361 tttgcttttt tcaaaagtat gttacagtaa tttcccaagg aggttttaca gaaatgaatt
      421 ttgttgccat ggattttgaa actgccaatc atcagcctta tagtgcttgt tctcttgcgc
      481 tagtcatggt aaaaaatagc cagatcgttg atgaattcta tacattgata cagcctgaga
      541 ctcctttttt ctggcgaaat gtccaaattc acggaatcca tcaagaagac gtacgcaatg
      601 cgccgaaatt cccagaagtc tggcaaacta tccaaccata ttttcaaaaa aatcgtttag
      661 tcgttgcaca taatgctgct tttgatacaa aggtcttagc gggatgctta gattattatc
      721 atcttgaaca gcctaattat ctttctttat gtacagtgaa aagtagccgt cgcctgtttc
      781 ctgaatttcc aaatcatcga ttgaacactg tgtgcgaaaa tttgaacatc caattagatc
      841 atcaccatga tgcattggaa gatagtcgtg catgtgcgga aatcctgctt tatcaagaaa
      901 aaaaattcgg gacagatcca ttgaaaaaac ttgtgactat aaagtaaaag aatacttatg
      961 aaacacacaa agaggtcgtg agcctgccgt ttcactccga gtcacaagga gcaatttcaa
     1021 aaaatagctt ctcatgttta ttaaatattg tgactggtga ccgaggagct ggcaggagaa
     1081 caccgtttat tggagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
     1141 acaaaaatag cttctcatat ttttcatttg gttggactta ttaccgcaga tgcaagcttt
     1201 tggacaccgt ttacc
//
LOCUS       DADGHT010000229         1195 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.237, whole genome shotgun sequence.
ACCESSION   DADGHT010000229 DADGHT010000000
VERSION     DADGHT010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.237"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1076
                     /locus_tag="JX887_002904"
     CDS             <1..1076
                     /locus_tag="JX887_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAX1258819.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DADGHT010000230         1149 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.238, whole genome shotgun sequence.
ACCESSION   DADGHT010000230 DADGHT010000000
VERSION     DADGHT010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.238"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>1149
                     /locus_tag="JX887_002905"
     CDS             <1..>1149
                     /locus_tag="JX887_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAX1258820.1"
                     /translation="DINEFMSSVLSLATLSLIVFLLIGNIYFLFSNAFFDMNQLVFNL
                     MLLQSFASFVISYIQSYFTINFNHFKYLILSFISTFLNIAISVALMQTLYFDDKYVGR
                     VVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYALKISLPLIPHSLANIVLAQFDRI
                     MINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWVPWFYGEMSKNNEKKVKKVSNYY
                     LVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVPITLGYFFQFLYSLPVNAEFYEK
                     KTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTTVFTYFLLFIFHYNIAKKITNKQ
                     LFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTSLLIISLVIYFLK"
BASE COUNT          361 a          139 c          177 g          472 t
ORIGIN      
        1 atgacataaa tgaatttatg tcatcggtac tttctctagc tacactttcg ttaattgtgt
       61 tcttattaat agggaacata tattttttgt tttcaaatgc tttttttgat atgaaccaac
      121 ttgtatttaa tttgatgtta ttacaaagtt ttgctagttt tgtaattagt tatatccagt
      181 cttattttac gattaacttt aaccatttta aatatttgat tttatctttt atatctactt
      241 ttttgaatat tgcaatctct gtagctttga tgcagacatt atattttgat gataaatatg
      301 ttggcagagt agtcggcgga acactgtcat ttgtgttgat aggtttagta atttatttaa
      361 gaataatgat aaagggtgct catttttttg ataaaaaaca gtggagatac gctttaaaaa
      421 tctctttgcc gctaatccca cattccttag caaatatagt tttagcacaa ttcgatagaa
      481 ttatgattaa ttcttattta ggtcctgctg cggggggaat atattcctac attagtaaca
      541 taggtattat tctaagcgta atatggatgt ctactaataa cgcctgggtt ccatggttct
      601 atggtgagat gagtaaaaat aatgaaaaaa aagtgaagaa agttagtaac tattatttag
      661 tagtctttac tttgattacg atgattgtaa tggtagtttc gattgattta gcaaaattta
      721 tggctccgaa agactattat tctgggttat ctttagtggt tccgataacc ttaggctatt
      781 tctttcagtt tttatatagt ttaccagtta atgctgaatt ttatgagaaa aaaacatcgt
      841 ttattgcgat tggtacagta gcaagtgcta tagttaatat actattaaac atgattttca
      901 tacctaggtt aggaataatt gctgctggat acacaaccgt atttacgtat tttttacttt
      961 ttatttttca ttataatatc gctaaaaaaa ttacgaataa acaattattt gacacaaaaa
     1021 aaatatgtat cataataatt tttgtatcaa ttttttcttt gatacttcat attttaatca
     1081 atcaaatgtt gattcgttac gttttgacat cattattgat aattagttta gttatatatt
     1141 ttttaaaga
//
LOCUS       DADGHT010000231         1141 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.239, whole genome shotgun sequence.
ACCESSION   DADGHT010000231 DADGHT010000000
VERSION     DADGHT010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.239"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            269..>1141
                     /locus_tag="JX887_002906"
     CDS             269..>1141
                     /locus_tag="JX887_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAX1258821.1"
                     /translation="MTYTHLTTDELVIIESYFKINQSVAKTAHCLNRSRQTIHKVYLF
                     FKKGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNN"
BASE COUNT          403 a          191 c          190 g          357 t
ORIGIN      
        1 tttaatataa ctaaattcta taacattaga agaaatttta aatacctttg ataaaaaata
       61 ttgatgtttt ttctctcatt gtttacaaac tagatagctt atgtattctt attaaaaata
      121 atagatattt cgaacatcat cactctcatc tacttaattt cgcattttta ctttacgccg
      181 attgtaaaat taagctagac aactaaaaaa gtcatttgtg ctacactcaa aatagttccg
      241 accaaagaat tataaggagt gagtacaaat gacctatacc catcttacaa cggatgaact
      301 tgtaataata gagtcttatt tcaaaattaa tcaatctgtt gctaaaactg cccattgctt
      361 gaatcgttca agacaaacga tccataaagt atatctgttc ttcaagaaag gaaaatcagc
      421 cttagaatat tatcaacagt ataagaaaaa caaatcaaac tgtggtagac gtccgcttgt
      481 tttacccgag gaacaatcag aatatattca aagaaaggtt gttcaaggat ggacacccga
      541 tgtgattgtt ggtcgtgcag cgtttcctat tagttgttct gctcgtacca tttatcgtat
      601 gttcaaaaag gggctatttg attcttctga cttaccgatg aaaggcaagc gtaaaccgaa
      661 tggacatcaa gaaagacgtg gaaaacaaac tttccgccgc tctattcatg aacgtgaaaa
      721 ggattatagc caattctcaa atgagtttgg tcaccttgaa ggtgacacta tcgtaggtct
      781 gaaacataaa agtgctgtaa ttaccttagt tgaacgatta tcaaaagtta tcatcacatt
      841 gaaaccgtgt ggtagacaag cgattgatat tgaaaaaaaa ttaaatcaat ggtttgaatc
      901 tgtaccgaaa aacctattca aatccatcac ttttgattgt ggaaaggaat tttcaaattg
      961 gaaacagatc agtaatgtca atgatattgc catttatttc gctgatccag gaacgccgtc
     1021 tcaaagaggc ctaaacgaga attctaacgg attgttacgt agagatggtt tattgaaatc
     1081 tatggatttc aattcagtag atgaattttt tattcaatct gtcgcatcta aacgaaataa
     1141 t
//
LOCUS       DADGHT010000232         1136 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.240, whole genome shotgun sequence.
ACCESSION   DADGHT010000232 DADGHT010000000
VERSION     DADGHT010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.240"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1061)
                     /locus_tag="JX887_002907"
     CDS             complement(<1..1061)
                     /locus_tag="JX887_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1258822.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITE"
BASE COUNT          301 a          254 c          182 g          399 t
ORIGIN      
        1 tcttcggtta ttctttcttc ccaggatttt ggtcttaagg cctcattcag attgataaac
       61 agctttttta ctcgtttctg atactccttc atgacctttt tcattaatgt tttgattcta
      121 cgactataga ttccatagcg acgaatcgtt ttgaaattct tattttgaat atggcgaatc
      181 agtgcagcta tgaattcgtc tatactcatg gtcatcgtct ctttagtatt cgttcgtttg
      241 tccatgtagt tgaacatgac agtgtcgcca tcatacatta agattcggct taatgcgatc
      301 gggccacgct tcatataacg actgatgtat tggagtagtg actttagatt tgtcctgctc
      361 cttttaggag catttacgta aaacccttct ccattgttct tgtacgcagc ttgtaatctt
      421 gattgaactc tttgcttgtc ccactcacct aacgttcgtc taattagttt caatacagca
      481 tttttccagt attttcttaa catagaaaaa ggtaaataat cgtattcttc ccaacttcca
      541 tctcttgtta agccacccat agtaacaacc atatgaacat gcggattaaa ttctagtttt
      601 gatccaaagg tgtggattgt agctactata cctgccttca cctttctttt ctcaaaatag
      661 gcaagaataa tttttgcggc ttcatccatt agtcctttca gtaaggaatc tcgatagttt
      721 tccatcataa agatttcccg taacccctca tcgatcgtaa agattacgtg ccgatgtgtc
      781 actttaaaca tatcattcgc cacaaccgct gaccaccttt ggctttcacc tgttgcacac
      841 gttggacaga actttccacg acatttcaag ggaacaaact ttgtttgatg acatccctcg
      901 cagacaaaca gtcggtatcc tttttgaata tctccacaat atctaaactt gtttacttcc
      961 cgtttgacga ctagccgaat ctttcgcccg tatttctcaa caaagttatc ccaattatgg
     1021 tgttcgtcaa aaaagattgc ttcgagaata ttcgctttca tagtaatatt ttacttgttc
     1081 aaaaacaaaa tgaaaagggc taaaagactg gtagtgcagc ctttttagcc cttaac
//
LOCUS       DADGHT010000233         1135 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.241, whole genome shotgun sequence.
ACCESSION   DADGHT010000233 DADGHT010000000
VERSION     DADGHT010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.241"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            24..503
                     /locus_tag="JX887_002908"
     CDS             24..503
                     /locus_tag="JX887_002908"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258823.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
     gene            complement(732..1031)
                     /locus_tag="JX887_002909"
     CDS             complement(732..1031)
                     /locus_tag="JX887_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258824.1"
                     /translation="MKKPTLSELIEAAEKAVKPDDWYRQSLILEKFHGMSKTTLVEYC
                     KEMETIPEFAEGILRPGHSTTFIHYHTFIWFLKWKDANKYRVKSLSPSDVLKEAS"
BASE COUNT          340 a          212 c          166 g          417 t
ORIGIN      
        1 tataattctg gtggggtgaa aacatgagca gaaaaattga taatataata ttgttaacaa
       61 ctatttttta tttagtaatc ggagcaactc tttccttact gtcatttttg tccaacagta
      121 gtttgattgt gttaaatcaa aaaagcatat taacagaatt tgcccacata gattacttct
      181 ctttttttaa aactggacta atatgtttat ttctatcttc atttatcctc tatataggaa
      241 ctacattttg tctaatggtg cttaatttaa aaatgtttat aattgaaaaa tggatagtta
      301 ttatcgcaaa gattttctca tcgatatcaa ttatcattcc aatgacattg acgttttcta
      361 aagagcaatt taacgtagct actacattcg tatcttttat agctctattt tcgtttgctg
      421 ttcctaaaac ttttcaaagc aaatctagca acgcaaaggt taatgtagaa aacactgata
      481 gaaaaaatga tgaaagttat taaaaaaaat aattctttca tttattgtca aacctttctt
      541 atagacatta gactttttta gtcagtccct cccgactggc ttttttgttt tgtactcagc
      601 ttcatccagc cctataaaaa tccaaaccat gtacacaatc gtacctatca acgcttgtct
      661 gcttccccag aggcctaaag cgtagatgat tagcggtgcg ctgaatacta gtgctctgtt
      721 gaatttgccc attaacttgc ctccttcaaa acatctgaag gcgataaact ttttacacga
      781 tatttgtttg cgtctttcca ctttaaaaac caaataaaag tatggtaatg aataaatgtg
      841 gttgagtgac ctggacgaag tattccttct gcaaattcag gaattgtttc catttccttg
      901 cagtattcaa ctaaagtagt ttttgacatg ccgtggaact tctccaagat taaactttgt
      961 cggtaccagt cgtctggttt tactgccttc tcagcagctt ctatcagctc tgaaagtgtt
     1021 ggttttttca cttattatcc ctcctaaaaa ttatcgttcc atactcgatg tttaacattt
     1081 cttgaagctc tgattttgta agaatgattt tatcttccaa cgactttacc tccct
//
LOCUS       DADGHT010000234         1088 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.242, whole genome shotgun sequence.
ACCESSION   DADGHT010000234 DADGHT010000000
VERSION     DADGHT010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.242"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>1088
                     /locus_tag="JX887_002910"
     rRNA            <1..>1088
                     /locus_tag="JX887_002910"
                     /product="23S ribosomal RNA"
BASE COUNT          287 a          250 c          332 g          219 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagc
//
LOCUS       DADGHT010000235         1072 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.243, whole genome shotgun sequence.
ACCESSION   DADGHT010000235 DADGHT010000000
VERSION     DADGHT010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.243"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            125..>1072
                     /locus_tag="JX887_002911"
     CDS             125..>1072
                     /locus_tag="JX887_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAX1258825.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMRGKRKPNGHQEKRGKQQYQRSIHDRSDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYS"
BASE COUNT          384 a          194 c          188 g          306 t
ORIGIN      
        1 ccgcactatg ccattacatt tatatctacg cgaattgtaa aattaagtta gaaaaataaa
       61 aaggcattta tggtacactc aaattgtatt tccgacgaaa gaaaacaaag gagtgtaacc
      121 ataaatgacc tacaaacatc ttaccataga cgaactgaca atgatagaat catattatct
      181 tcaacataat aagccggttg aaatcgctaa ccgaatggga cgtgctatac aaactattta
      241 taatgtagtc aataagttca agcaaggcaa gactgctctt gattattggc accagtataa
      301 agaaaataag aaaaaatgtg gtagaaaagt cattcaatta cctgctcatg aagtagatta
      361 cattaaagag aaagtcactc ttggttggac gcctgacgtc attatcgggc gaaaagaaag
      421 gtctgtttca tgcggtatga gaacacttta tcgtttattt tctaaaggaa tatttgatat
      481 tgacacacta ccgatgagag gtaaaagaaa acccaatggc catcaggaaa aacggggaaa
      541 acaacagtat cagcgctcaa tccatgatcg atctgataat tatcctgatt tcaattctga
      601 gtttggtcac cttgaaggtg atacgatcgt tggcattcat cataaaagtg ccgtcattac
      661 tttagttgaa agattatcta aagtcattat cacgattaaa cccaacggcc gtaaggcatt
      721 agatattgaa actgccctta atcaatggtt ttctcgcttc cctaaaaact tctttaaatc
      781 tattacgttt gactgtggaa aagaattttc taactggaaa gccattagta accaacatga
      841 tattgatata tattttgcgg accctggaac accttctcaa cgcccattaa acgagaattc
      901 taacgggatt ctgcgtcgta atggactgcc gaaatcaatg gattttagaa aagtgaatca
      961 gacatttatt tccagtgtca gcaatcaacg taatcatatt ccaagaaaat cattgaatta
     1021 cagaacacca atcgaaatat ttttgagcta tgtacaagaa gcattttatt ct
//
LOCUS       DADGHT010000236         1064 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.244, whole genome shotgun sequence.
ACCESSION   DADGHT010000236 DADGHT010000000
VERSION     DADGHT010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.244"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(37..993)
                     /locus_tag="JX887_002912"
     CDS             complement(37..993)
                     /locus_tag="JX887_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258826.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          178 c          160 g          380 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aact
//
LOCUS       DADGHT010000237         1045 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.245, whole genome shotgun sequence.
ACCESSION   DADGHT010000237 DADGHT010000000
VERSION     DADGHT010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.245"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            6..980
                     /locus_tag="JX887_002913"
     CDS             6..980
                     /locus_tag="JX887_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAX1258827.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          376 a          132 c          182 g          355 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaac
//
LOCUS       DADGHT010000238         1033 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.246, whole genome shotgun sequence.
ACCESSION   DADGHT010000238 DADGHT010000000
VERSION     DADGHT010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1033
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.246"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..946
                     /locus_tag="JX887_002914"
     CDS             <1..946
                     /locus_tag="JX887_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAX1258828.1"
                     /translation="SCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMTK
                     NITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMIL
                     ELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYCH
                     LYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSRD
                     FVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEER
                     SGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          330 a          162 c          223 g          318 t
ORIGIN      
        1 gagctgttat cttatcaccg gtggggctgg cttcattggt tctaccttag ccaatcattt
       61 aggagaagaa catgtggtaa tcgtcgtcga tgacttatca atgggaaaag tagaaaatct
      121 tgatatgacg aaaaatatca cttttattga gggagatgtc gctgagaaat ccttgatgga
      181 agagatcatg aaagctaata aatttgatta tatctttcat ttagcagcag ttgctagtgt
      241 ggcagattca gttgcccgac cagtagaaac acatcgtgtg aattttgaaa gtgtattaat
      301 gattttagaa ttgatccgca agtatcaacc tgatttaaaa cggatcgtgt ttagttcttc
      361 agcggctgtt tatggggatg aaccgacttt accaaaaaaa gaagagtccg tgattcgccc
      421 attgacgcct tatgcggttg ataaattcgc tgcagaacaa tatgtgctag attattgtca
      481 tttatatgat gtacccggta gcgcagttcg ttttttcaat gtctatggtc caaatcaaaa
      541 tccgaattct ccatacagtg gtgtgatttc tattctcgta gatcgctata agaaacaaat
      601 cgtaggagaa gcaacttcat ttacattatt tggtgatgga agccagtcta gagactttgt
      661 ttatatagat gatgtaatcc aagcattact tttagttgcg aatgaggaag ctgcactggg
      721 gaaacaattc aatgttggaa cgggtaaagc aaccacactt ttggaattga ttcatgcaat
      781 caatgaaatt ctcggtgtag aattgacact tgaatacaaa gaagagcgtt cgggtgatat
      841 ccatgactct ctagcagata ttactaagat ccagtcaatt ggctatcaac cgaaatatgg
      901 tattttaagt ggaatgacta attatttgaa aactgaaatc aattaaaaca tactaagata
      961 agattagagg gtaaattcag gctctttgtc aataaggact gatgagtttt gtaaaatcaa
     1021 atctgggata gaa
//
LOCUS       DADGHT010000239         1021 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.247, whole genome shotgun sequence.
ACCESSION   DADGHT010000239 DADGHT010000000
VERSION     DADGHT010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.247"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..425)
                     /locus_tag="JX887_002915"
     CDS             complement(<1..425)
                     /locus_tag="JX887_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAX1258829.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
     gene            complement(534..>1021)
                     /locus_tag="JX887_002916"
     CDS             complement(534..>1021)
                     /locus_tag="JX887_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAX1258830.1"
                     /translation="RNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNLNRKENRLN
                     KVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKITVYKNVSP
                     ELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHELAAFVRVSS
                     I"
BASE COUNT          325 a          175 c          181 g          340 t
ORIGIN      
        1 ggaatctgtt ttgattttgt tccatttgaa atttctctca ctcgcttttt tgtctcatca
       61 tcaaataaaa tgaaagggtc ttctaaacga tcgataaata cttccattgt tgttgttggt
      121 agatgataag aagtcatgac aggcactgca ccaaggtaag acacagaaac agctagaagg
      181 tatgtgtcaa aagcggaact cttataaata ataactttgt ctccggattt cactccaaga
      241 tgagccaatt gataagcccg tttcaacaca ctttcgcagc attttttgta agttgtttca
      301 agtcctaatt ctgggaaagc tgaaagtggc tcatcaaaga taatcggggt ctcggaaaag
      361 ttagctgcag cttcttgaaa attcgtaaat aagttcaaag gggaatacgt tatggtctcc
      421 atcattcaca ctccattatc ttttgttaag taatatacaa attcaagata atcgtaacat
      481 aatcctttat ataataacat agtttattgt gaaaaaaaga tcatacattt gttttatatg
      541 gaagaaaccc gaacgaatgc cgctaattcg tgataagaaa aatcaaccat cttttcccag
      601 atatcttgaa aagaatggga tgagaggtat cgattaccac ataaataatt taccgcgtca
      661 gcatcatcta aatatagttc tgcataataa cgatatgttt ttctgcatag ttctggcgat
      721 acgtttttat atactgtaat tttgctcaaa atttggcgaa tagtccgagg agaaatttgc
      781 tgatcatgtg aggaacgaaa aacaaaagaa ttttcgtccg tattttgtgc tgttaactta
      841 aaatagttct ccagaaatgg catcgcttct tttggtattg gtactttatt cagtctgttt
      901 tcttttctat tcagattaag aatctgcttg gtcaaagata catctttacg tttaagttct
      961 actacttcat ggatctttaa tccgcaatac agaagaatgg cagtaattgc aaggttcctc
     1021 g
//
LOCUS       DADGHT010000240         1019 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.248, whole genome shotgun sequence.
ACCESSION   DADGHT010000240 DADGHT010000000
VERSION     DADGHT010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.248"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..422
                     /locus_tag="JX887_002917"
     CDS             <1..422
                     /locus_tag="JX887_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAX1258831.1"
                     /translation="ILFLIKASNMYVFLILSSVGYMGLGVFNTVIWANITDVIDDQEV
                     KSDQREDGTVYAVYSFARKIGQALAGGVGGWTLSIIGYDSLANVQTGDVLEKLYNAST
                     LIPSICFLIVGLILFFLYPLSKDKVLENCELLKQKHK"
     gene            432..>1019
                     /locus_tag="JX887_002918"
     CDS             432..>1019
                     /locus_tag="JX887_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAX1258832.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLD"
BASE COUNT          364 a          112 c          202 g          341 t
ORIGIN      
        1 tgatcttatt tttgataaaa gctagtaata tgtatgtatt cttaattctt agttcggttg
       61 gctatatggg tttgggtgtg tttaatactg ttatttgggc aaatattact gatgttattg
      121 atgatcaaga agtaaagtct gatcaaagag aagatgggac cgtatatgcg gtatattctt
      181 ttgctagaaa aataggtcaa gctctagctg gaggcgtcgg aggttggact ctttctatta
      241 taggctatga ctctttagca aatgtacaaa cgggagatgt tttagaaaag ttatataacg
      301 cttcaacatt aattccatca atttgttttc tgattgtagg attaatttta tttttccttt
      361 atccattatc taaagataaa gtcttagaaa attgcgagct tttaaaacaa aaacataaat
      421 aggagagaaa tatgaataat tggatatttt gtattgattc agatggctgt gttatggata
      481 cgatgactta taaacacaat ctctttttcg gaccaattgc tgcagagatt tttgatgttc
      541 atcatagaga aaaattccta caggattgga ataatattaa tttatattca gagactcgtg
      601 gaataaacag atttttaggt ttagttaaaa cattagaaaa aaatgatgta acatcgatta
      661 atcgattaaa gcactgggta tctctaacaa aagaattgtc taatccatct ttgaagaggg
      721 aaatagaata ttctcagtca gaggatttat taaaagcttt aaaatggtcg gaagaagtca
      781 atcaacagat tagtcaagca aaaggattag ataaaccctt tttaagtgct agagatacta
      841 taaaagctct gaaaaaatat gggaagataa ttattgtaag ctcagctaat aaggaagctg
      901 ttcaagaaga atgggaaaga catgaattat tatcattagt tgatgaactg tgttgtcaag
      961 ataaaggaaa aaaagaagat attattcgaa gtgtaattga aaatggttgt gatttggat
//
LOCUS       DADGHT010000241          991 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.249, whole genome shotgun sequence.
ACCESSION   DADGHT010000241 DADGHT010000000
VERSION     DADGHT010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.249"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            359..991
                     /locus_tag="JX887_002919"
                     /pseudo
     CDS             359..991
                     /locus_tag="JX887_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          339 a          181 c          182 g          289 t
ORIGIN      
        1 agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa caccttcaat
       61 tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt aaacgaatta
      121 ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag tgcaaatatt
      181 aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga tctatatatt
      241 catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata taggctctat
      301 aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt ttaggtatat
      361 gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa ggaccctgcc
      421 aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata aaatgagctt
      481 tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac gaaaattgtc
      541 tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat atttagtgac
      601 agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg cgaaagtcgt
      661 cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt ttcgtgtaca
      721 agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag tgaaaaagaa
      781 ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca aaacatggcg
      841 cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg atcgattgct
      901 ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga ccgaagcctt
      961 tagagacaag gaatcagact tattttttac c
//
LOCUS       DADGHT010000242          991 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.250, whole genome shotgun sequence.
ACCESSION   DADGHT010000242 DADGHT010000000
VERSION     DADGHT010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.250"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            172..459
                     /locus_tag="JX887_002920"
                     /pseudo
     CDS             172..459
                     /locus_tag="JX887_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            473..904
                     /locus_tag="JX887_002921"
     CDS             473..904
                     /locus_tag="JX887_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258833.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            906..>991
                     /locus_tag="JX887_002922"
     CDS             906..>991
                     /locus_tag="JX887_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAX1258834.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLC"
BASE COUNT          368 a          145 c          210 g          268 t
ORIGIN      
        1 gctaaatact taaaaacgca tgtagaagct attgatggta aagaagcatt ggtgcagaca
       61 gatggagacc aagccattgc aggacataag aatttttcag gttctgtaac aatcaataat
      121 aaacgtgttt tgacgactga tgataacaga tatgaagtgg taaatctggt tgtcactaac
      181 ggtaatacag ggacagcaaa gctttatcgt gaaggaaaaa cagtttctat atattttgtg
      241 gctttaaacg gaaaaagtag tggcgggaat gattcggtta ttttaactgt tccagaaggc
      301 tatcggacac caattagttt tgaacaactg gttgggtcaa tagaccgttc tactttgaac
      361 agtgctcaac tatctattgg cgcagacgga gccattaaat ggagaagaaa ttcaagttat
      421 ggatcagctt attcatttgt tatcacttat tcaatttaag ggaggaaatc taatgaaagt
      481 agtttacaaa tcaatcaagc cttacggatt cgagcaaatc attttgaaca atcaagaaaa
      541 tatccctgaa aactgtacag agattaaacc accagttcct aactggagac caagatttga
      601 ttttgataaa aaacagtggg ttgagttagc tactgaagaa gagaaaaaag ggaatgctgt
      661 tgatagcgta gatgaattgg ctaatattaa ggcattatac gaaacgctga aggcagaaaa
      721 tgatgaattg aaacagctaa attctaaagc aatgctaaac aatgtagcaa tcaagcaaga
      781 aaatgtctta ttgaaagaaa agtcagaaag tttagcgcag ttgaattcaa aaacgatgct
      841 tgcttctgta caaaatacca aggaaatcga agaaatcaaa aaacaattac aaggtgggaa
      901 gtaacatgta ttcatatgaa gatatcaaac taatgtatga ctggggctgt ttcactaacg
      961 aacaagtaat ggttttcgtt ccgttgtgca t
//
LOCUS       DADGHT010000243          975 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.251, whole genome shotgun sequence.
ACCESSION   DADGHT010000243 DADGHT010000000
VERSION     DADGHT010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..975
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.251"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>975)
                     /locus_tag="JX887_002923"
     CDS             complement(<1..>975)
                     /locus_tag="JX887_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAX1258835.1"
                     /translation="SYHVPTGTPGLLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSL
                     ISVLISKITKTIRVFYMMNFIVQIFYITLSSSRGAQVVICSFLVLFLLLFANSKFRKS
                     IREVLPVKIKWMVSILLVLLVYFSFGTNYAKDFLATIPVSIDRKVEVIESNESDKTPL
                     PEKEVILQHSSDNSEISAGRFTIWKAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDL
                     DTTDVNELKRAHGNMHNGFLQVLVSSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAF
                     LGIVLIFILSIFIDEMVEAHVLFNKRDVISIVFWYYLGSISYLYLKKEN"
BASE COUNT          374 a          170 c          120 g          311 t
ORIGIN      
        1 attctccttt tttaaataca agtaagaaat gcttcccaaa taataccaga aaacaattga
       61 aatgacatcg cgcttattga aaagtacatg agcctccacc atttcatcta taaaaataga
      121 tagtataaaa attaaaacaa taccaagaaa cgcataattc actttacttc taaaaaatgt
      181 tttgagtaaa ctaaagatat ttaacacata gaaagcatag atacatataa aagcaattat
      241 accacttgat acaagtactt gaagaaatcc attatgcatg tttccatgtg ctctttttag
      301 ttcattcaca tctgtagtat caagatctac ttttttcaaa aattttgcat cgctattccc
      361 atagaaatcg gtctctccat aaccaaataa caaagttggt cttataactt taagcgcagc
      421 tttccaaatc gtaaaacgac cagctgaaat ttcggagtta tcactagaat gctgtaatat
      481 tacttctttt tctggaagtg gagttttatc tgattcattt gactctataa cttctacttt
      541 tctatcaatc gatacaggaa ttgttgctaa aaaatcctta gcataattag taccaaaaga
      601 aaaatatacc aatagaacta ataatatgct taccatccat ttgattttta caggtagtac
      661 ttctctaatg ctctttctaa attttgaatt ggcaaacaac aaaagaaata atactaaaaa
      721 agaacaaatt actacctggg cacctctaga cgaagaaagt gtaatataaa atatttgtac
      781 gataaaattc atcatataaa aaacacgaat cgtttttgtt atttttgaaa ttaatacact
      841 aattaaactt aaaataatag aagtatatcc aaacatagct ccaacatttg gacttgtata
      901 gacaccaaat aaccgatgtt caataaaacc ttgtcttgca agtaatcctg gcgttcctgt
      961 tgggacatga taaga
//
LOCUS       DADGHT010000244          970 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.252, whole genome shotgun sequence.
ACCESSION   DADGHT010000244 DADGHT010000000
VERSION     DADGHT010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.252"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            76..>970
                     /locus_tag="JX887_002924"
     CDS             76..>970
                     /locus_tag="JX887_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAX1258836.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHY"
BASE COUNT          329 a          182 c          192 g          267 t
ORIGIN      
        1 ggtattaaaa aacatatcgt tctctagtat gattaaatca ccacaaaata aacaactgag
       61 aggacgatac gctatatgaa tgattctatc aaaaaaatgc tgagaataac agagaaagat
      121 ttgatgatta cagaggtctc ttacgagacc cttcagaaga aaaagacgtt ggtcgtcgat
      181 gctgttctct cgcctactcc tcgtgcttgt agaagttgtg gttctactgt ggtagatgga
      241 aacgggaaag caattatagt gaaaaatgga aaaaaggaaa cgattgtccg ttttgaacaa
      301 tacaatcata tgcctttggt tatgcgccta aaaaagcaac gctatacctg taaaaactgt
      361 cgcacccatt ggacggctca aagttatttt gtccaaccca gacattcaat cgcaaatcat
      421 gttagatata aaattgcttc tttactgact gaaaaagtat ctttatcttt tattgcgaaa
      481 agctgtcagg tatctttgac caccgttatt cgtacattga aagagtttaa aagctattta
      541 ccaaagcaat ctaagaagat cctccccaga gtattgatgg ttgacgaatt tcgttcgcat
      601 gcttccatag aagataagat gagctttatt tgcgcggatg gcgaaacagg aaaattaata
      661 gatgttttgc ctacgcgtaa attacctcga ttaacaagct atttcttagg ttgtaccaat
      721 ccagaagaag tagaattctt ggtgacagac atgaacgccg cctacttcca gctcaccaaa
      781 cgtgttctgc caaatgcgaa agtcgtgatt gatcggtttc atattgtcaa acacatgaat
      841 caagcgttca atgagttgcg tatccgtgaa atgaatgaac ttcgtaaagc cggacagaaa
      901 agccaggcag aaaaactgaa aaagaactgg cgctttttgc taaaaaatcg tgcaaacatc
      961 aaccattatg
//
LOCUS       DADGHT010000245          948 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.253, whole genome shotgun sequence.
ACCESSION   DADGHT010000245 DADGHT010000000
VERSION     DADGHT010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.253"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..939
                     /locus_tag="JX887_002925"
     CDS             <1..939
                     /locus_tag="JX887_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1258837.1"
                     /translation="INNEFNLGPNEGSSQVANNQYILLHETANETATGRNEAQYMKRS
                     WTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKATFEKNYKA
                     YVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKL
                     AYDLAHGFTDENPTTSDDKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIENANLHVAG
                     WHIANYKYEYIFIMDYNTGKELARVKADGIYRPDVNQAYNTLGNVGYHVSFNMRNFPN
                     KKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPQR"
BASE COUNT          331 a          180 c          196 g          241 t
ORIGIN      
        1 atcaacaatg aatttaattt gggcccaaac gaaggtagct ctcaagtagc aaataatcag
       61 tacattttac tgcatgagac agctaacgaa acagcaacag ggcgcaatga agcgcagtat
      121 atgaaacgtt catggactag tgcttacact gcttatattg tgggagacgg cggaattgtt
      181 taccaagtcg gacaacctgg ttatgtacag tacggtgctg gttcgtatgc taatgctaac
      241 agtcccgtgc agattgagtt acaacacaca catgataaag caacgtttga gaaaaactac
      301 aaggcatacg ttgaattagc tagagattca gcaatgaaat atggtattcc acttacacta
      361 gacacaccgt ataatcaacc agggatcaaa tcgcatttat gggtaacaca aaatatttgg
      421 ggcgatcata cagatcctta cggttatctt tctgaaatgg gcgtaagtaa agaaaaatta
      481 gcctatgatt tggctcatgg atttaccgat gaaaatccga caacttcaga tgataaacca
      541 gtcattgatc caactcgagc aggtgctgca aatcctaccc tgacagatgg aacaaattac
      601 gcccacattg atcagttcgg agaaatcgaa aacgcaaact tacatgtggc tggttggcac
      661 atcgctaact ataaatacga gtatatcttc attatggatt acaatactgg gaaagaatta
      721 gctcgagtaa aagctgatgg aatatataga ccagatgtaa atcaagctta taatacttta
      781 ggaaatgttg gctatcatgt atcttttaac atgcgcaact tccctaataa gaaagtctat
      841 gtaatgatgc gggcaacgaa tgatccagaa gggaacacta aaggcggagc acaagatttt
      901 catgataaac gctggtattt aaatattccg caacgataaa aatagccc
//
LOCUS       DADGHT010000246          948 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.254, whole genome shotgun sequence.
ACCESSION   DADGHT010000246 DADGHT010000000
VERSION     DADGHT010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.254"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>948
                     /locus_tag="JX887_002926"
     CDS             <1..>948
                     /locus_tag="JX887_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HAX1258838.1"
                     /translation="QMLIDNGYASFMTPFVWMFISSYEKLRSFLINERNISSLIQMEY
                     SAFEEATVPICTFTIKNSNEQDGSYIKLSDFKGGMEVQKIKTLEAIHQHGECDYFYST
                     NQDNFKKIPGMPIAYWASDNVITDFAQGKLTNDVADAKQGLATGNNNKFLRYWFEVEF
                     NKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKWYGNNEYVVNWENDGDEIKNYVNENGK
                     LKSRPQNLNYYFKKGITWSTLSSGQVSFRLQNQAIFETKGSVLFSKDITDFEEIFGYV
                     NSKLVNHFLTFISPTLDYHEGPMGKLPFLKVTSERKLKK"
BASE COUNT          357 a          127 c          172 g          292 t
ORIGIN      
        1 gccaaatgct gattgataat ggatatgctt cctttatgac gccatttgtt tggatgttca
       61 tttctagcta tgaaaagtta cgctcatttt taattaatga aagaaacatt tctagtttga
      121 ttcaaatgga gtattcagct tttgaagaag caaccgttcc aatttgtacg tttacgataa
      181 aaaattcaaa tgaacaagat ggaagctata taaaattatc agattttaaa ggtggaatgg
      241 aagttcaaaa aattaaaacg ttagaagcaa ttcatcagca tggtgaatgc gattattttt
      301 atagtactaa tcaagacaac ttcaaaaaaa tcccaggaat gccgattgct tactgggcaa
      361 gcgataacgt aatcactgat tttgctcaag gaaaattaac taacgatgtt gcagatgcaa
      421 aacaagggtt ggcaaccgga aataacaata aatttttgcg gtattggttt gaagtagaat
      481 ttaacaaaat aaagtttgat gctaaaacat tagaggacgc taaaaagtct agaaaaaaat
      541 ggtttcctac aactaaaggt ggtcgtttta gaaaatggta tggaaacaat gaatacgtgg
      601 ttaactggga gaatgatgga gatgaaataa aaaattatgt taatgaaaat gggaagttaa
      661 aatctagacc acaaaatctt aattactatt ttaaaaaggg aattacttgg tcgacacttt
      721 catctggaca agtatctttt agattgcaga atcaggcaat ttttgaaact aaaggatctg
      781 ttctgttctc aaaggatata actgactttg aagaaatatt tggctatgta aactctaaat
      841 tagttaatca ctttttaact tttatttctc ccaccttgga ttaccatgaa ggaccaatgg
      901 gaaaactacc ttttcttaaa gttacatctg agagaaaatt aaaaaaaa
//
LOCUS       DADGHT010000247          937 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.255, whole genome shotgun sequence.
ACCESSION   DADGHT010000247 DADGHT010000000
VERSION     DADGHT010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.255"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..360
                     /locus_tag="JX887_002927"
     CDS             <1..360
                     /locus_tag="JX887_002927"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258839.1"
                     /translation="IVELKKRCNSLINTSKTVKTISHQTKESIKKILLIGVPGKIVIR
                     EDYNFIITNPDTPLEDIIKIIEENDINELWITTFQLIPRMKKKIIQSLKNKIKIQELN
                     DFTMLMKEENINGFKTR"
     gene            341..>937
                     /locus_tag="JX887_002928"
     CDS             341..>937
                     /locus_tag="JX887_002928"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258840.1"
                     /translation="MVLKQGKQDYQIIGYLEDDLNKIKINSDDVMYFFMTPLSDFPSS
                     VIDNVEGIQIYSNTLTKFGFIDDINESHSTRAQSLKEFLDPYIIVCTPKIKRNHEQAR
                     NYYQGDDLELIPKPKSEVFKNLIKENESLVPIPVFSINNSDSVIKDETSFENQLLNGK
                     LLGKIINFSKDNEDYPLNVFWENTDGSRVLFGEIIGQNN"
BASE COUNT          398 a          117 c          133 g          289 t
ORIGIN      
        1 atcgttgaac tgaaaaaaag atgtaatagt cttataaata caagcaaaac agtaaaaact
       61 atttcacacc aaacaaaaga aagtataaaa aagattttat taattggtgt tccaggaaaa
      121 attgttatta gagaagacta taattttata atcactaatc ctgatacacc tctcgaagat
      181 atcattaaaa taattgaaga aaatgatatt aatgaattat ggattacaac ctttcaatta
      241 attcccagaa tgaaaaaaaa gattatacaa agtttaaaaa ataaaataaa aattcaagaa
      301 ttaaatgatt ttactatgct tatgaaggag gaaaatataa atggttttaa aacaaggtaa
      361 acaagattac caaattattg gttatttgga ggatgattta aataaaatta aaataaactc
      421 ggatgatgta atgtactttt ttatgactcc tctttcagat ttccccagta gtgtgattga
      481 taatgtagag ggtatacaaa tatatagtaa tacgcttact aaatttgggt ttattgatga
      541 tataaacgaa tctcatagta ctcgtgccca atcacttaaa gaatttttag atccttatat
      601 tatcgtttgt acaccaaaaa ttaaaagaaa tcatgaacaa gcaagaaatt actatcaagg
      661 tgatgattta gaattaatcc ccaaaccaaa gtctgaagtt tttaaaaatt taataaaaga
      721 gaatgaatca ttagtaccta taccggtctt ttctataaat aacagcgatt ctgtaatcaa
      781 agacgagaca agttttgaaa accaattact aaacggcaaa ctactcggaa aaattataaa
      841 tttctcaaaa gacaatgaag attacccttt aaatgttttt tgggagaaca ctgatggatc
      901 aagagtttta tttggtgaaa taatcggaca aaacaat
//
LOCUS       DADGHT010000248          928 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.256, whole genome shotgun sequence.
ACCESSION   DADGHT010000248 DADGHT010000000
VERSION     DADGHT010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.256"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..928
                     /locus_tag="JX887_002929"
                     /pseudo
     CDS             1..928
                     /locus_tag="JX887_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          341 a          159 c          176 g          252 t
ORIGIN      
        1 tggttcattc aaagaaaaag ataatcttac gcctgaacaa aaagaattgt tagaactacg
       61 taaaagaaac cagcaattag aaatggaaaa tgatatttta aagcaagcag cgctgatatt
      121 cggacgaaga gacaagtaat cgatgcgaat aagcatcttt accctatatc agcgatgtgc
      181 agaatattag gtctatcacg tcagtcctat tattatcaat caaaaccaaa gaaagacgaa
      241 tcagaacttg aagaagtagt cgctgaagaa tttatccgca gccgaaaggc ctacggctca
      301 agaaaaataa aaaaagcctt atcaaaacga ggcattcaga tcagccgacg aaaaattagt
      361 agaatcatga aaaatagagg attaaaatcg agctatactg ttgcttattt taaagtacat
      421 cattctactt gcaatgaagc caaaacgaca aacgtattga atcgtaaatt cttaagagac
      481 aacccattag aagcgatcgt aacagacttg acttatgtac gagtcgggaa aaaatggaat
      541 tatgtctgtt tcattttgga tctgttcaat cgagaaattc tcggctattc ttgtggagaa
      601 cataaagatg ccgttctagt aaaaaaagca tttagccgta tcaaacaacc tctgacagag
      661 gttgagattt ttcatactga tcgtggaaaa gagtttgata accaagctat tgatgaatta
      721 ttaacaactt ttgacatcaa tcgatcattg agtcataaag gctgtccttt tgataatgcc
      781 gtagctgaat caacttataa gtcgttgaaa gtagaatttg tctatcaata cacatttgaa
      841 accttacaac aattggattt ggagttattt gactatgtca attggtggaa ccaccttcgg
      901 ttgcacggta cacttggcta cgagacac
//
LOCUS       DADGHT010000249          906 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.257, whole genome shotgun sequence.
ACCESSION   DADGHT010000249 DADGHT010000000
VERSION     DADGHT010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.257"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..720
                     /locus_tag="JX887_002930"
     CDS             <1..720
                     /locus_tag="JX887_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAX1258841.1"
                     /translation="GKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFT
                     NRLGTNKRGRLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVY
                     LANCYTLEGRKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITL
                     EEFQQANEIHCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNK
                     VQLIRLNKYRVLAGNQELNLI"
BASE COUNT          339 a          143 c          178 g          246 t
ORIGIN      
        1 gggaaaacgg aattagaaga aacaagactt tataattcaa tggtattagg tatgcaaaat
       61 tattatcaga ttgcaacgaa tgtaaatctg gattgtatga aactgaatag agctgtaatg
      121 gctatcttca ctaacagatt aggtacaaac aaaaggggca gattgagaaa aacaggcaga
      181 caacttacga caaaggaggc aacaagatat ggtaaatcta aaatgcttcg gtatgttgct
      241 ggcgagggcg aacctatttt ccctgttgga tatatccaac acagaaaacc aatggcaaag
      301 gtgtatttag cgaattgcta cactctagag ggaagaaaat ttatccacac caatctaagt
      361 gttgataaat tactgatgta ccagttaatg aaattatctt tggaaaatcg cacaatagaa
      421 tacgcagaca atcgaatttc gctattttct gctcaacatg gaaaatgtgc tataactctg
      481 gaagaatttc aacaagctaa tgaaatacat tgtcatcata ttgtaccaac tggagctggt
      541 ggaaatgacg attataaaaa tcttattttg gtaaaagagg cggtacaccg tctaatacac
      601 gctaaaacag aagaaacaat acaaaaatat atagctctat tgaagctaaa taaagtccag
      661 ctcataagac taaataaata tagagtatta gctggcaatc aagaattaaa cttgatatag
      721 gtctactaca taaatacttt tcaatataaa cacgatggaa cgcggagtgc ggtgaaagtc
      781 gcacgctccg tgtgaatggg gggaaaagtt tgagatattt ataatatcag gaacttacct
      841 atccatatat caatggtttt taaccaatgc tcaatcttta gtcttactag cgattgtggt
      901 cattgg
//
LOCUS       DADGHT010000250          892 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.258, whole genome shotgun sequence.
ACCESSION   DADGHT010000250 DADGHT010000000
VERSION     DADGHT010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.258"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..189
                     /locus_tag="JX887_002931"
     CDS             <1..189
                     /locus_tag="JX887_002931"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258842.1"
                     /translation="DLEKLTKQRDMKNFNNCVVLIIITELTLFTNIYYIHEAQSSLIE
                     DWAIFMAKEGKEMFQNKG"
     gene            211..477
                     /locus_tag="JX887_002932"
     CDS             211..477
                     /locus_tag="JX887_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAX1258843.1"
                     /translation="MDSLPVELQALCWNLIDQNVQKQFPLDYLQIFEFSTEKGNQKLV
                     HRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY"
     gene            504..803
                     /locus_tag="JX887_002933"
     CDS             504..803
                     /locus_tag="JX887_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HAX1258844.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
BASE COUNT          324 a          117 c          191 g          260 t
ORIGIN      
        1 gatttagaaa aacttactaa acaaagagat atgaaaaact ttaataattg tgtagttttg
       61 ataattataa ctgaattaac tttatttaca aatatatatt atatccatga agcccaatct
      121 tctttaatag aagattgggc tatttttatg gcaaaggagg gaaaagaaat gtttcaaaat
      181 aaaggataac gttatgtcac aaagggagta atggacagtt tgccggtgga attacaagct
      241 ttatgttgga atctaatcga tcaaaacgtt caaaagcaat ttcctttaga ctatcttcaa
      301 atttttgaat tttctacgga aaaaggaaat caaaagttgg ttcatcgtca agaagaaccg
      361 gaagaaagaa aagagtatct gatttcacct aagcttcgtt tgaaatcagt gtctcaaaaa
      421 atatgggcca ttgattcggg tgagtatcaa acgatgttat taccagaaga atactagtat
      481 ctaaaagaaa ggaacgaaag gacttgttag aaacggctat cgaagtactg gaaaagtgtg
      541 cacagctggt cactgcttct gaagagtggg gctatgaatc cgttacgatg gaaaaagagg
      601 aaattgaaat gggtatgctt cctgaagatg ttcatctacc acgtttagtg atgacacatc
      661 tttatattta ttgcgcacca gaagatggaa aagactatgt agtttatttc attacagata
      721 ttaccagcca gcgagaattt gttcgtgggt tactggtaga aggacgattg gtttggagtc
      781 agattggagg aacggatgaa taagatcgat tatttgagaa tgattgcgaa atgtttagaa
      841 gatatcctta ccgcgattca tcaaattctg aagaaaaaag gagaaagaat at
//
LOCUS       DADGHT010000251          890 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.259, whole genome shotgun sequence.
ACCESSION   DADGHT010000251 DADGHT010000000
VERSION     DADGHT010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.259"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..888
                     /locus_tag="JX887_002934"
     CDS             <1..888
                     /locus_tag="JX887_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAX1258845.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          244 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt
//
LOCUS       DADGHT010000252          866 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.260, whole genome shotgun sequence.
ACCESSION   DADGHT010000252 DADGHT010000000
VERSION     DADGHT010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.260"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            4..>866
                     /locus_tag="JX887_002935"
     CDS             4..>866
                     /locus_tag="JX887_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAX1258846.1"
                     /translation="MNGFAYTINNEFNLGANEGSSQVANNQYILLHETANETATGRNE
                     AQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKAT
                     FEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEM
                     GVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIEN
                     ANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRADVNQAYNTSGNVGYHVSF
                     NMRNFPNKKVYV"
BASE COUNT          294 a          157 c          178 g          237 t
ORIGIN      
        1 ccaattaacg gatttgccta tactatcaac aatgaattta atttgggcgc aaatgaaggt
       61 agctcacaag tagcaaataa tcagtatatt ttactgcatg aaacggctaa tgaaacagca
      121 acaggacgca atgaagcgca gtatatgcaa cgttcatgga ctagcgctta tactgcttat
      181 attgtgggag acggcggaat tgtttatcaa gtcggtcaac ctggttatgt acagtacggt
      241 gctggttcgt atgctaatgc caacagtcct gtgcagattg agttacaaca cacacatgat
      301 aaagcaacgt ttgagaaaaa ctacaaggca tacgttgaat tggctagaga ttcagcaatg
      361 aaatatggta ttccattaac gttggacact ccttataacc aaccgggaat caaatcgcat
      421 ttatgggtaa cacaaaacat ctggggcgat catacagatc cttacggtta tctttctgaa
      481 atgggcgtaa gtaaagaaaa attagcatat gatttagctc atggatttac cgatgaaaat
      541 ccaacaactt ctgaaaacaa gcctgtcatt gatccaacac gagctggtgc agctaatcct
      601 acactgacag atggaacgaa ttacgcccac attgatcagt ttggagaaat cgaaaatgca
      661 aatttgcatg tagctggatg gcacattgct aactataaat acgagtatat cttcattatg
      721 gattacaata ctgggaaaga attagctcga gtaagagctg atggaattta tagagcagat
      781 gtaaatcaag cttataatac ttctggaaat gttggctatc atgtatcttt taacatgcgt
      841 aacttcccta ataagaaagt ctatgt
//
LOCUS       DADGHT010000253          850 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.261, whole genome shotgun sequence.
ACCESSION   DADGHT010000253 DADGHT010000000
VERSION     DADGHT010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.261"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..690
                     /locus_tag="JX887_002936"
     CDS             <1..690
                     /locus_tag="JX887_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258847.1"
                     /translation="LKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYFVYCPELLLYDV
                     KNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYGIDETDIFAKVN
                     SIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTLLISPISTISFS
                     PSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLSEEKILLPENWA
                     ELRKLVEYGII"
     gene            677..>850
                     /locus_tag="JX887_002937"
     CDS             677..>850
                     /locus_tag="JX887_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAX1258848.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSI"
BASE COUNT          322 a          108 c          121 g          299 t
ORIGIN      
        1 ttgaagaaga gtatattttc aacaagtaaa aacgttcaaa gagtttttaa aatattaaat
       61 aaaaatagca tcttcaaaaa aaaaattgac gattattttg tctattgtcc ggaattgtta
      121 ctttatgatg taaaaaatat aaaaaaaatt cccaaaatag atgaaaacag taaattgatg
      181 aaaaacatac aatcaatctt tgggatagaa gaagtttttg tcggagataa atgtatcttt
      241 tttgatcaac ctttattatc tgatggttat ggcatagatg aaacagatat tttcgctaaa
      301 gtaaatagta tattttctgg aaaaaaagaa actttaatta agcttcatcc tagagcaagg
      361 acaaatcgtt atggtgaaaa aaacatattg aattccagtt taccgtttga agtcttgcta
      421 cttgaaaatg acttctcttc aacacttttg attagtccta tatctacaat ttctttttca
      481 ccatctatga tgtttgaaaa gacgatcaac tctattatgt tggctaaatt aattttaaat
      541 gaatatacag cattatctga agataaaaaa gaaacattga caaatattgt tcttttctgt
      601 gaacattata accgtctatc agaagaaaaa attttactcc cagaaaactg ggcagaatta
      661 agaaagttgg tagagtatgg gattatttaa cacactttcc aagtcaaaat tagttaagtc
      721 cagtttctgg tatactatag ggaatttttt tattaaggga atttcattca taactattcc
      781 tatttttgta aatattacta ctcaagcaga atatggtttg attaataatt tcacttcatt
      841 tgtatcaatt
//
LOCUS       DADGHT010000254          830 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.262, whole genome shotgun sequence.
ACCESSION   DADGHT010000254 DADGHT010000000
VERSION     DADGHT010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.262"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>830
                     /locus_tag="JX887_002938"
     CDS             <1..>830
                     /locus_tag="JX887_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HAX1258849.1"
                     /translation="YNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLVNQFNTLKS
                     NEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCIFGRYSLDE
                     DGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVEITFGKETL
                     EENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGKQNGFKALM
                     YLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTKEIVKIQKQ
                     "
BASE COUNT          299 a          140 c          148 g          243 t
ORIGIN      
        1 tataatgctc ttgaaacgtc atacgagttt agaagaaaca ttttgttaag ttatatgttt
       61 aaaaaagatc tctcagaggc atttaactgt ctaagtaggc agttggttaa tcaatttaat
      121 actctaaaat cgaatgaaga ggaactgaac gacatattca ttaatcatta ttctcttgaa
      181 aaagaattaa caaaagaggt tcaagatgaa tatatctctg caaggttacc tgataaggcg
      241 agggaaatta aggattttat ttcttattca ataggttgta tcttcggtcg ttactcccta
      301 gacgaagatg gtctcatctt cgctggcggc gaatgggatc cttcccgcta tcaaaaattt
      361 aaacctgata ctgataatgt tttactcatc accgatgatg agtatttcaa ggatagccaa
      421 attgacattg tcaatcgttt cattgatttc gttgagatta cttttggtaa agaaaccctt
      481 gaagaaaatc tccagtttat cgctgacact ttaggtggca aagggacaag tcgagaaatt
      541 attcgtcgtt acttcgtaca agatttttac aaagaccatt taaaaacata ctccaatcga
      601 ccaatttatt ggcaattgga ctcaggaaaa caaaatggct ttaaagcgtt aatgtacttg
      661 catcgctata caccagatca attaggaaaa gtacgtactg aatacctaca cgaactacaa
      721 aaagcgtatg acaatcgaat cgaattgcgt cagcaacaaa tttcaacaag tgataaccca
      781 aaagaaagaa atgcaatgac aaaagaaatt gtaaagattc agaagcaatt
//
LOCUS       DADGHT010000255          798 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.263, whole genome shotgun sequence.
ACCESSION   DADGHT010000255 DADGHT010000000
VERSION     DADGHT010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.263"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(68..140)
                     /locus_tag="JX887_002939"
     tRNA            complement(68..140)
                     /locus_tag="JX887_002939"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(105..107),aa:His,seq:gtg)
     gene            complement(143..216)
                     /locus_tag="JX887_002940"
     tRNA            complement(143..216)
                     /locus_tag="JX887_002940"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(182..184),aa:Trp,seq:cca)
     gene            complement(223..303)
                     /locus_tag="JX887_002941"
     tRNA            complement(223..303)
                     /locus_tag="JX887_002941"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(267..269),aa:Tyr,seq:gta)
     gene            complement(305..380)
                     /locus_tag="JX887_002942"
     tRNA            complement(305..380)
                     /locus_tag="JX887_002942"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(345..347),aa:Phe,seq:gaa)
     gene            complement(416..488)
                     /locus_tag="JX887_002943"
     tRNA            complement(416..488)
                     /locus_tag="JX887_002943"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(453..455),aa:Asp,seq:gtc)
     gene            complement(498..570)
                     /locus_tag="JX887_002944"
     tRNA            complement(498..570)
                     /locus_tag="JX887_002944"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(535..537),aa:Val,seq:tac)
     gene            complement(586..657)
                     /locus_tag="JX887_002945"
     tRNA            complement(586..657)
                     /locus_tag="JX887_002945"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(622..624),aa:Glu,seq:ttc)
     gene            complement(672..761)
                     /locus_tag="JX887_002946"
     tRNA            complement(672..761)
                     /locus_tag="JX887_002946"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(725..727),aa:Ser,seq:gga)
BASE COUNT          220 a          220 c          185 g          173 t
ORIGIN      
        1 cgaaccaacg catgagggag tcaaagtccc ttgccttacc gcttggctat accccaagaa
       61 taaaaagggc gaatgatggg aatcgaaccc acgaatgccg gagccacaat ccggtgcgtt
      121 aaccacttcg ccacattcgc catggcaggg gcagcaggaa ttgaacccac actaacggtt
      181 ttggagaccg ctgttctacc tttaaactat gcccctataa aatggaggag agtggattcg
      241 aaccactgaa ccctaaggaa cggatttaca gtccgtcgcg tttagccact tcgctactcc
      301 tccatggtgg cgcgggacag aatcgaactg ccgacacacg gagcttcaat ccgttgctct
      361 accaactgag ctaccgcgcc atattttaaa attattaatt gaataacaag aacgacggtt
      421 ccgacgggaa tcgaacccgc gatctcctgc gtgacaggca ggcatgttaa cccctacacc
      481 acggaaccag ttcattatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg
      541 cagatgctct cccagctgag ctaaacctcc aacattcaat taaaatgacc cgtacgggat
      601 tcgaacccgt gttaccgccg tgaaagggcg gtgtcttaac cgcttgacca acgggccagg
      661 taaatttgct acggagagta agggattcga acccttgaga cagtttggca ccatctacat
      721 gatttccaat catgctcctt cggcctctcg gacaactctc cagagtgaaa gaagctcaat
      781 actctttctc aaaatgag
//
LOCUS       DADGHT010000256          784 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.264, whole genome shotgun sequence.
ACCESSION   DADGHT010000256 DADGHT010000000
VERSION     DADGHT010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.264"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            22..714
                     /locus_tag="JX887_002947"
     CDS             22..714
                     /locus_tag="JX887_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAX1258850.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT          282 a          151 c          158 g          193 t
ORIGIN      
        1 aaaaaaagga ttttagtaac aattggtcta gcttttttgt tagctggttg taccaacggg
       61 aatgaatcga aaaaagaatc aacaaaagaa acagcgaaag caacagttgc aactactaca
      121 acaactagca cagagagcaa gtcaactgca gcaagtacag aaacagcaga tacctctact
      181 tcgtcagagt cttccaaaac gactgaaaca actcaaacat ctacttcaag ttcttctgta
      241 gaggcttcat cttcctcttc agaaagcagc gaacaagttg aacaaacact gtggaatgca
      301 gacaaatccg cacaattaga ggcatttatg accaaatggg gccaaacaat gggacaacaa
      361 tacaaaagtt atacgaatca aatgagtgtg gacttatatg gtcttaaagt ccctcaagct
      421 attttgaacg gggagtggaa gatggctatt ggtggagtgc ctgtttctgc agaatggtca
      481 gaaagtggga caggtcaagc agactatcaa atcacagccg tctattccga tgcagagaca
      541 gaaccatatc tgaaaaagca cgtctatcta ttcgggtttc agcaaaatca gccaaaagta
      601 ttggtgacac aacaaaatca ggggaatccc gataattatc tttacttcaa cgagacagcg
      661 aataatgaat tgaaaaatgg ctttaatcaa atcgtttatg gacaagcaaa ttaatgagat
      721 aaacaagggg ttgtgacatg tcttttatca caaccccttg ctcagtttat ttgttagtct
      781 ttta
//
LOCUS       DADGHT010000257          783 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.265, whole genome shotgun sequence.
ACCESSION   DADGHT010000257 DADGHT010000000
VERSION     DADGHT010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.265"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            330..560
                     /locus_tag="JX887_002948"
     CDS             330..560
                     /locus_tag="JX887_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258851.1"
                     /translation="MMEDFIRKNISDEYADFYEQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
BASE COUNT          270 a          119 c          128 g          266 t
ORIGIN      
        1 aaaatttgaa aagcaatttc cgtgaatttc ttcttatttc ttggagttaa acgcttctgt
       61 tccagcctct ttttatctgt ctttcactaa tgatcagttg tagataagca agttgctttt
      121 tcttacatca taccgcccat caagacaaac gtttttagct tgtacgtact ggacaaaaat
      181 cccattatat caagaaaaaa caacgttgat aatacttaaa attattaggc tagaacggac
      241 tagtaagagt tttttgcccc ttttttgccc ctcaaatatc gctttacagc cagaacataa
      301 gttcgtataa tcgttttgag gtgattttta tgatggaaga ctttattaga aaaaatatca
      361 gtgatgaata tgcagacttt tatgagcaaa gcagcaaaaa agataaattc cagatggatg
      421 tttcaatttt agctatatta gctttttccg aaaataaaca acctgtaact gcaaaaaaag
      481 aaacagtatt ctctgaaggc aaaataaaaa ctcgatatat attagaggta gaaactaagt
      541 ttaaaaatag atcggagtaa tggctatgct ttttaatgag acgcaattat ggtttaaatt
      601 cgatccttcg aatagatttg tcaaagattt ttataaggtg tgggattcag aagttttctt
      661 tttagcaatc gaagatagct tattaatcaa tctctactat tctaataaga actatttcaa
      721 aattcctgct gcgaaaacta gaatgaagaa ggatgtatac tttttgtttg atatcgtgac
      781 tga
//
LOCUS       DADGHT010000258          771 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.266, whole genome shotgun sequence.
ACCESSION   DADGHT010000258 DADGHT010000000
VERSION     DADGHT010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.266"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            116..482
                     /gene="ssrA"
                     /locus_tag="JX887_002949"
     tmRNA           116..482
                     /gene="ssrA"
                     /locus_tag="JX887_002949"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT          251 a          126 c          150 g          244 t
ORIGIN      
        1 aaaggggcag ttattatata aataatggga tatgattcgc ttttttattg aatttatccc
       61 aatatatgct atactaattt tgtatgaaaa atacacgtaa cccttgttag ctaacgggga
      121 cgttacggat tcgacaggca cagtcgagct tgaattgcgt ttcgtaggtt acgtctacgt
      181 aaaaacgtta cagttaaata taactgctaa aaacgaaaac aactcttacg ctttagctgc
      241 ctaaaaacag ttagcgtaga tcctctcggc atcgcccatg tgctcgagta agggtcctaa
      301 ctttagtggg atacgtttca actttccgtc tgtaagttga aaaagagaac atcagactag
      361 cgatacagaa tgcctgtcac tcggcaagct gtaaagtgaa tccttaaatg agttgactat
      421 gaacgtagat ttttaagtgg cgatgtgttt ggacgcgggt tcgactcccg ccgtctccat
      481 atatgtatgg ttgagacaga taaacatgta tgaaaaacgt tgttaaatca acgttttttt
      541 attttggtca aggagagaaa agtagagaaa tacaaaattt tttgcattga ttttgcattc
      601 aaaaaaacat tcaaacattt agaaatcccc aatacgtatt caggaaaatc tattttaagg
      661 tttacaaaaa gaacttttgt tcgtacactc tttttgaggt gaacttttat gctgatggaa
      721 ggaaaaacac aattatggtt taagcatgtt ccttcaaata agttttttta a
//
LOCUS       DADGHT010000259          763 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.267, whole genome shotgun sequence.
ACCESSION   DADGHT010000259 DADGHT010000000
VERSION     DADGHT010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.267"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(237..761)
                     /locus_tag="JX887_002950"
     CDS             complement(237..761)
                     /locus_tag="JX887_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258852.1"
                     /translation="MIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVE
                     LDVNNYRELYVFNSLDVEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKNIKKCDKC
                     FESAVVKFPQFKLNPAASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKK
                     AFKIKTIGTAPNFK"
BASE COUNT          261 a          102 c           85 g          315 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttatattt
      481 ttacctttgt aaaaatattc gattgaatat tctatttggc acgactcact tggcagtata
      541 tgtatgtcaa tatttttcat ctgtttcata ggtatttcaa catctaaact attaaaaaca
      601 tataattccc tgtaattatt tacatctaac tctactaaat ttatctttgg aacaatagat
      661 cctccaccca ttccaccata ataaaaaaaa tcttgttctc tatcaaaata gcacatatta
      721 agctcagttt gtttatcatc ctcaataatt ttataaatca aac
//
LOCUS       DADGHT010000260          682 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.268, whole genome shotgun sequence.
ACCESSION   DADGHT010000260 DADGHT010000000
VERSION     DADGHT010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.268"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(137..427)
                     /locus_tag="JX887_002951"
     CDS             complement(137..427)
                     /locus_tag="JX887_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258853.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
BASE COUNT          287 a          109 c           99 g          187 t
ORIGIN      
        1 ttgttactat gaataacata ataagaaagt aaagtggatt gatttgagat ctttttatac
       61 ttcaaaaaag ataacaccca actttcaaaa atatgttttg gaagttggga caaacgagtt
      121 aatacatttt aatacattat tttttattca aaaaaaatag cacaatggca aagatcgtaa
      181 gagagatcat aagccccaat gaatgactaa aaagaaaagc agaatcacat gccatatcat
      241 cccatatttc ttcaagaaaa taaataagcg ggaaaaaggg aaggaatagt agaacatcga
      301 tccagcacca tttttttctt cttttgaaat aacataaaac aataaacatg aacgtgcagg
      361 gaagtaaaaa caaagcttta ctcataacta acaaaatacc agctcctttt atttttttct
      421 cccccacatt caaagagtaa caatggtatg tacttaataa tagaaaaatg gatcaacttg
      481 tatgaataac agctgaaaag atctgcacca aataaaaaac ttccagccaa aactgactgg
      541 aagtttattt ttttctgaaa tattctaaca caaatatgaa aaagatggcc gaagctaata
      601 agccgatttc gtagcaaaac aatgagatac cagagtcgta ataataaaat cctctaatct
      661 tatggataaa atagatcatc gg
//
LOCUS       DADGHT010000261          628 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.269, whole genome shotgun sequence.
ACCESSION   DADGHT010000261 DADGHT010000000
VERSION     DADGHT010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..628
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.269"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            10..423
                     /locus_tag="JX887_002952"
     CDS             10..423
                     /locus_tag="JX887_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAX1258854.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
BASE COUNT          226 a           95 c          113 g          194 t
ORIGIN      
        1 tgatcaaaaa tggcaaatgt acctagcatt cgcgacatgt tccctgattt caatgacgtg
       61 tttagtccag cattcaatga ttttttaggt gtttcaagtt atccaaaagt agatttagtc
      121 gaaaatgaaa aagaatacaa actaactgct gatatgcctg gctgtgacaa agaagacacg
      181 acagttgaat attcagataa tactttgacg atctccgcca atcatgagtc ccatacagaa
      241 gataaagaag atggcaacta tgtacggaaa gaaagacatt cggtctctta caaacgttca
      301 ttctatcttc ctaatgttga tgaagaaaaa atcactggaa cctttaaaaa cggtgtgctg
      361 aaattggtat tacctaaaac agcttatcag ccaaaagaaa caaaaaaaat tgagttaaat
      421 tagaacttat cgcctctcga tgaatgaggg gcgattttta tatatttgga taagaacgag
      481 tatgtttaaa ttttcaaaat gagcaaaaaa atattttgtt tttacgataa agatgttatg
      541 atctctcttg gtaaaaaata tgggagttga tcatttgatt gtcttaagta aacttttgtt
      601 ttggatacca tttatcataa tgaccagt
//
LOCUS       DADGHT010000262          602 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.270, whole genome shotgun sequence.
ACCESSION   DADGHT010000262 DADGHT010000000
VERSION     DADGHT010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.270"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            3..>602
                     /locus_tag="JX887_002953"
     CDS             3..>602
                     /locus_tag="JX887_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HAX1258855.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFM"
BASE COUNT          229 a           77 c          118 g          178 t
ORIGIN      
        1 aagtgtttaa aggaaaaaca atattagtaa ctggcggaac tggttccatt ggaagtgaaa
       61 ttgttcgtca gcttttaaaa tatgaaccaa aagctatcag aatttatagt agaggtgaag
      121 aaaaacaatt ttatatgcaa caagagctct caaatcacac taatttgaga tttttaattg
      181 gtgatatcag agactctcaa aggattgatt atgcatgtcg tgatgtggat attatttttc
      241 atgctgccgc aatgaaacac gttccagcaa gtgaatataa tcctatggaa gctgtaaaaa
      301 caaatgtgat gggaactcaa aatgtaatag atgcagcgat caaaaataat gtaaaacatt
      361 ttgtaggtat cagtacagat aaagtagtga gtcctactaa caccatgggt gcgacaaagt
      421 tattgagtga aaaattaata atagctgcca atcagtataa aggaaaaaca gaaacaatat
      481 tttcttgtgt aaggtttgga aatgtcatgg ggtcaagtgg atctgttatt cctcttttta
      541 gtaaacaaat aaaaaacaat aaagatatta ctttgacaga tgttgatatg acacgattta
      601 tg
//
LOCUS       DADGHT010000263          581 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.271, whole genome shotgun sequence.
ACCESSION   DADGHT010000263 DADGHT010000000
VERSION     DADGHT010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..581
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.271"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..581
                     /locus_tag="JX887_002954"
                     /pseudo
     CDS             1..581
                     /locus_tag="JX887_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          193 a          107 c          131 g          150 t
ORIGIN      
        1 gaaatggaga atgatatttt aaagcaagcg gcgctgatat tcggacgaaa agacaagtaa
       61 ttgatgccaa caagcataaa tattccatat cagcgatgtg caaaattcta aatatttctc
      121 gtcagaccta ctattatcaa gcgaaaccga tcgaaaatga gtccgactta gaagagatcg
      181 ttcaggaaga gtttattcga aaccgaaagg cttacggtac ccgaaaattg aagaagtgtt
      241 tagcaaagcg tgggcttcaa ctcagtcggc gccgaatcgg tcgaatcatg aaacgccgcg
      301 gattgacatc tacctatacg atcgctcatt ttaaagggca acgaacagct tgtaatgaag
      361 cgaaaacagc gaatgtatta gatcggacct ttacacaaga acagccattg gaagccatcg
      421 ttacggatct tacttatgtt cgcgtgggga aaaagtggca ttatatctgc ttaatacttg
      481 atttgtttaa tcgagaaatt attggttatt cctgtggtga gaagaaagat gcctcattgg
      541 taaaagaagc ctttggacgg ataccgtatt ctttaacaga c
//
LOCUS       DADGHT010000264          576 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.272, whole genome shotgun sequence.
ACCESSION   DADGHT010000264 DADGHT010000000
VERSION     DADGHT010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..576
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.272"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            80..>576
                     /locus_tag="JX887_002955"
     CDS             80..>576
                     /locus_tag="JX887_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HAX1258856.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          217 a          106 c           93 g          160 t
ORIGIN      
        1 aaaaatccat acaaaaaagg aagtcccttc tgtagaataa agttaacgac aaccaattca
       61 cagaaaagag gacttcccta tgaatgattt tactacagaa attgtgcaaa ctctagtcac
      121 taaaggcgat ttaaatgaat tattccgttc gcacttagaa aaagcgataa acacactcct
      181 acggactgaa ttaacggctt ttttagatta cgaaaaatat gatcgcactg gttttaattc
      241 aggtaattcg agaaacggtt cttactttcg atcaatcaaa accgaatatg gtgaattaac
      301 attggaaata cctagagatc gtaatggtga gtttaaacaa caaactttac cagcctacaa
      361 aagaacaaac gatacattgg aaaccactat tatccattta ttcgaaaaag gtgttacgat
      421 gtctgaaatt gctgatttga tcgaaaaaat gtacggtcat cactatactc cacaaaccat
      481 gtccaacatg actaaagttc tgactgaaga agtaaatgcc tttaaatcca gagccttaaa
      541 tgataagtat gtcgctattt ttatggacgc tactta
//
LOCUS       DADGHT010000265          575 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.273, whole genome shotgun sequence.
ACCESSION   DADGHT010000265 DADGHT010000000
VERSION     DADGHT010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.273"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            312..>575
                     /locus_tag="JX887_002956"
     CDS             312..>575
                     /locus_tag="JX887_002956"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAX1258857.1"
                     /translation="MSAVVTDLTYVRVGTNWAYICLMIDLFNREIIGHSCGNKKDAQL
                     VKRAIQSIPYSLQEIELFHTDRGKEFDNQTIQNLMNGLVIKFLS"
BASE COUNT          195 a          105 c           82 g          193 t
ORIGIN      
        1 ttttacactc tctattattc ttttcataaa tattgtaaat agaagtatta aaaatatata
       61 caaaaagtat tatttcgaga aagataaata ttttcaaaaa ccttttcata atcctcaccc
      121 tttcttacac tgataaatca tgcgtctaat attcaaatta tactcgatat gctttagcta
      181 atcagccaac tctgtttgtc tactatcatt atatcaatag acaatatctg ctcccgtctt
      241 tatgatcgtg ccaaagcaat caaaagaaaa ttgcgaatca cttagatcga aagtttactc
      301 aaacaaaagc attgtcagcg gttgtcacgg atttaactta tgttcgggtc gggacaaatt
      361 gggcttatat ttgtttgatg attgatttat tcaatcgtga aattattggc cattcttgcg
      421 gaaataaaaa agatgcgcag cttgtaaaaa gggccattca aagcattcct tactcacttc
      481 aagaaatcga actcttccat acggatcgtg gaaaagaatt tgataaccaa accattcaga
      541 atctcatgaa tggtttggtt atcaaattcc tttcc
//
LOCUS       DADGHT010000266          571 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.274, whole genome shotgun sequence.
ACCESSION   DADGHT010000266 DADGHT010000000
VERSION     DADGHT010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.274"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          186 a           81 c           81 g          223 t
ORIGIN      
        1 tcttgatgtg atatccttgt cttttttgta atgtttttaa cttattgctt ttgcaaaatt
       61 tatttacctg ttttctggat caacgatagt gtacattatg ctatccttgt ttggatttta
      121 ggacgtttaa agaggcactt ttttacataa cttaatccat agacctttta agcatgctgt
      181 gagataataa taaagaagag tttaaagcgc accccaaacc acttccccat aagtgtatta
      241 cgctttaaac tcttttatat ttgaattcac taagaagcat accatatttt tgaaaaaaag
      301 tgagaaaaaa ggcttataat taggatttag agtaattaat tagatgttta ttttatagga
      361 ctgatactat agattacaaa tagtatcgta tttcgcaatc ttaaaattat cttcttactg
      421 tgaataagat aataaaattt gtatttgtcc tttttaggta acttatttta atctatatac
      481 ctttctggat caacgaaagt atactttata tagtcataac gccgatggta actatgcact
      541 gtaacgataa tgctgctaaa atatcttttt a
//
LOCUS       DADGHT010000267          570 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.275, whole genome shotgun sequence.
ACCESSION   DADGHT010000267 DADGHT010000000
VERSION     DADGHT010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.275"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          209 a           67 c           75 g          219 t
ORIGIN      
        1 taatcataca aaatagtttt ttcataaaaa tatggaaaat atggattaat tttgaaataa
       61 ttgatttaaa aggaatacaa aagagtgaat agtaggaaat agtggtttag aactagtggg
      121 ctgatttttt atatatttta gtttacataa tatatattat acaaagtaga tttaaaaaat
      181 gataaacctc tctcgaacgg ttttttatca aaaatcgtca tttttccatc aaaatctgct
      241 tatgcaaaat tataaaaaaa ttttgcagtt tttcttactt tttttgtcgt ttaattgaat
      301 gataaaaacc agtttcttta ttcagttaat caaatatgaa cgaattagat atgaatcatt
      361 gtatttgccg ttgcggaagg attttttaat taaccacaga taaacattga taacgattcg
      421 cttattgtaa tcaacagatt aaatttcata tgttcatatg tacggataca ttttcggacc
      481 gattaatttt aaccattcta tttatttgct tacctattag atatcaataa aaaactgctt
      541 aacagctatt tcagctgtta agcagtttta
//
LOCUS       DADGHT010000268          569 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.276, whole genome shotgun sequence.
ACCESSION   DADGHT010000268 DADGHT010000000
VERSION     DADGHT010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.276"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>569
                     /locus_tag="JX887_002957"
     rRNA            <1..>569
                     /locus_tag="JX887_002957"
                     /product="16S ribosomal RNA"
BASE COUNT          139 a          131 c          173 g          126 t
ORIGIN      
        1 gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccagtggc
       61 gaaggcggct ctctggtctg taactgacgc tgaggctcga aagcgtgggg agcaaacagg
      121 attagatacc ctggtagtcc acgccgtaaa cgatgagtgc taagtgttgg agggtttccg
      181 cccttcagtg ctgcagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt
      241 gaaactcaaa ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa
      301 gcaacgcgaa gaaccttacc aggtcttgac atcctttgac cactctagag atagagcttc
      361 cccttcgggg gcaaagtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt
      421 tgggttaagt cccgcaacga gcgcaaccct tattgttagt tgccatcatt cagttgggca
      481 ctctagcaag actgccggtg acaaaccgga ggaaggtggg gatgacgtca aatcatcatg
      541 ccccttatga cctgggctac acacgtgct
//
LOCUS       DADGHT010000269          568 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.277, whole genome shotgun sequence.
ACCESSION   DADGHT010000269 DADGHT010000000
VERSION     DADGHT010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.277"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(23..>568)
                     /locus_tag="JX887_002958"
     CDS             complement(23..>568)
                     /locus_tag="JX887_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAX1258858.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSPVQFRKTTVTVV"
BASE COUNT          163 a          105 c          100 g          200 t
ORIGIN      
        1 ttcatgctct aaaatgatat ttttacacaa ctgttacggt tgttttacga aattggacgg
       61 gactttgcca gtttaatttc tgttttatcc gttcattatt gtagtaatag atatagctat
      121 cgatggctga ttttaattcc tcgaaacagt tataaacttt cccgtgaaaa atctcttgtt
      181 ttaataagcc aaaaaaattc tccataagtg aattatctaa gcagttccct ttccgagaca
      241 tgctttgaaa gattttgtac tccttcaatt tgtttctata agctttcatt tgatacgccc
      301 aaccttgatc tgagtgaaac gtacgacgat agggacaatc gttagtggtc tggatagctt
      361 cctccaaacc ttccattacc gctaatgcat tgggcttttc agagatacga taggataaaa
      421 tctcactatt gaacatatcc ataaaaggat ctagatacaa tttcttttga cggataatgc
      481 ctttggcatc cacttcatgg tatttaaatt cagttgtatc cgtcgtgatt ttctgatggc
      541 agatactggt gtagaaacga cgatggat
//
LOCUS       DADGHT010000270          525 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.278, whole genome shotgun sequence.
ACCESSION   DADGHT010000270 DADGHT010000000
VERSION     DADGHT010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.278"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..355
                     /locus_tag="JX887_002959"
     CDS             <1..355
                     /locus_tag="JX887_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAX1258859.1"
                     /translation="FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRP
                     GEKLYEELMTTDEIERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSG
                     QEFIRIAKENNVVTW"
     gene            367..>525
                     /locus_tag="JX887_002960"
     CDS             367..>525
                     /locus_tag="JX887_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAX1258860.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAP"
BASE COUNT          219 a           67 c           95 g          144 t
ORIGIN      
        1 atttggagaa acatatgtct taaaaatgcc ggcaatcaat attttaactt tagctcaatc
       61 attaataaaa atatataatg atacacatga tgaaaaatat agaggtgaaa taaaagttgt
      121 aggtatcagg ccaggagaaa aattatatga agagctaatg actacagacg aaattgaacg
      181 ctcatatgaa aatgataaaa tgtatatcat tccaccacac tatcatgcta ctgacgaact
      241 gtacaaagat tatgaaaaaa ttaaaatcac tgcatactct tcagatgcaa cagaattaat
      301 gagtggacag gaatttatta gaatcgcaaa agagaataat gtcgtgactt ggtaaggagt
      361 tttatgatga aatcagaagt atatgtaatt gcagaaattg gtgtaaacca taatggaagt
      421 ctagatttag ctttagaaag tattgataaa gctaaagaat gtggagctaa cgcggttaaa
      481 tttcaaacat ttaaaacgaa taagctagtt tccaaaaagg ctcca
//
LOCUS       DADGHT010000271          514 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.279, whole genome shotgun sequence.
ACCESSION   DADGHT010000271 DADGHT010000000
VERSION     DADGHT010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.279"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(107..>514)
                     /locus_tag="JX887_002961"
     CDS             complement(107..>514)
                     /locus_tag="JX887_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_465591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAX1258861.1"
                     /translation="GTPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMN
                     AASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYED
                     SQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          162 a          103 c           78 g          171 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttcc
//
LOCUS       DADGHT010000272          511 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.280, whole genome shotgun sequence.
ACCESSION   DADGHT010000272 DADGHT010000000
VERSION     DADGHT010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.280"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..425)
                     /locus_tag="JX887_002962"
     CDS             complement(<1..425)
                     /locus_tag="JX887_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAX1258862.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISG"
BASE COUNT          202 a           91 c           88 g          130 t
ORIGIN      
        1 ccgctgatcg gtagaatcaa taaaaaataa gcaaggaaaa acaaaaaagt aatgggtctc
       61 actttcttca gctgaagtat cgtcaagtgt aagagttgct tcaaagagat tggttctttc
      121 tttttaataa aaaaaacact catcaaaaga aaagtaaatt cgaaataaac taacagtaaa
      181 atcgtcatca aaactacgat taacgagagt agaaccccag gatgttgaga aaaaattgaa
      241 ggaatattgt cataagacaa atagtcaatt gcccctcggt gtaaaataaa acgggtcgta
      301 ctgctcaata agggtaaaca aataaataaa ataaagccat gcatcagcaa gacatcacgg
      361 aaataagctt gtgttccttt taaaaagtcc caagcattac ctaagctacg tttcaaataa
      421 ttcatcctat cacctgctct tcacattgta gcgcaaatct aatgaaaaag gaaagggtgc
      481 agtgtgtttt gcagaccctt tcccagattt a
//
LOCUS       DADGHT010000273          509 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.281, whole genome shotgun sequence.
ACCESSION   DADGHT010000273 DADGHT010000000
VERSION     DADGHT010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.281"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..132)
                     /locus_tag="JX887_002963"
     CDS             complement(<1..132)
                     /locus_tag="JX887_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAX1258863.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          183 a           93 c           91 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactatta
//
LOCUS       DADGHT010000274          508 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.282, whole genome shotgun sequence.
ACCESSION   DADGHT010000274 DADGHT010000000
VERSION     DADGHT010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.282"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          228 a           70 c           81 g          129 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactc
//
LOCUS       DADGHT010000275          502 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.283, whole genome shotgun sequence.
ACCESSION   DADGHT010000275 DADGHT010000000
VERSION     DADGHT010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.283"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..214
                     /locus_tag="JX887_002964"
     CDS             <1..214
                     /locus_tag="JX887_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAX1258864.1"
                     /translation="QLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            215..>502
                     /locus_tag="JX887_002965"
     CDS             215..>502
                     /locus_tag="JX887_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAX1258865.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFL"
BASE COUNT          192 a           57 c           98 g          155 t
ORIGIN      
        1 tcaattgttt actttagatg aatgtatcaa tgttgactta ttaaataata aaataagttt
       61 tgaagaaaac attgttaaag aaatgcctga atctgctaat gatatgtatg agaaggagtt
      121 gaaatatttc tttgaaaacg tagtaacagg caaagaaaac tggaatgatt tatatcatgc
      181 aaacgaagta ttgaaaatag ctgaggagaa ataaatggaa attttattta ctatttgtgg
      241 tagagctggg tctaaggggt ttaaaaataa aaatttgaaa tatttggcag gaaagcccct
      301 agtccatttc gctttagcaa tgatagatat ctatcaacaa aaacatcctg aacataattg
      361 cacgacttgt ttgaatacgg acagtaatga gttagtagaa ttgacgacta agttaaatcc
      421 gtctgtgaaa attgtagaac gtaaacctga attagctaca gatactgtag ggaaaattga
      481 agtgatacgt gattcattct ta
//
LOCUS       DADGHT010000276          493 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.284, whole genome shotgun sequence.
ACCESSION   DADGHT010000276 DADGHT010000000
VERSION     DADGHT010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.284"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(54..>493)
                     /locus_tag="JX887_002966"
     CDS             complement(54..>493)
                     /locus_tag="JX887_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAX1258866.1"
                     /translation="KKAEGSPCFLLYQTFPGIGALTAALLLGELGDITRFKTHKQLNA
                     FVGIDIRRYHSGKYTGQDRINKRGNPKARKIIFFTIRNMIRQQRAAPNHIVDYYYKLK
                     KQPIPKKDKVATVACMNKLLKCMHAMVRAHTEYDYAYAVSVDH"
BASE COUNT          133 a           92 c          115 g          153 t
ORIGIN      
        1 tcgtaaaaaa ttttcgatct gggcaaagaa gtggtatact gtaagtggtt tagttaatgg
       61 tccactgaga ccgcgtacgc atagtcgtac tctgtatgtg ccctaaccat agcgtgcata
      121 catttcagaa gcttgttcat acaagcaact gtggcaacct tatctttctt agggataggt
      181 tgctttttta atttgtagta ataatcgaca atatgattag gagctgcgcg ttgctggcga
      241 atcatatttc gaatggtgaa gaaaataatt ttccgtgctt tgggattacc acgcttattg
      301 atgcggtctt ggccagtata cttacctgaa tgataccgtc ggatgtcgat tccgacaaag
      361 gcattcaatt gtttatgggt tttaaatcgt gtgatatctc ctaattcacc gagcaataaa
      421 gcggctgtga gtgcgccaat cccagggaac gtttggtaca acaaaaagca aggagagcct
      481 tcggcttttt tga
//
LOCUS       DADGHT010000277          462 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.285, whole genome shotgun sequence.
ACCESSION   DADGHT010000277 DADGHT010000000
VERSION     DADGHT010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.285"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..430)
                     /locus_tag="JX887_002967"
     CDS             complement(<1..430)
                     /locus_tag="JX887_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAX1258867.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          132 a           92 c           59 g          179 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatttctag tc
//
LOCUS       DADGHT010000278          440 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.286, whole genome shotgun sequence.
ACCESSION   DADGHT010000278 DADGHT010000000
VERSION     DADGHT010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.286"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>440
                     /locus_tag="JX887_002968"
     CDS             <1..>440
                     /locus_tag="JX887_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAX1258868.1"
                     /translation="YTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIKIIRYF
                     FIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIV
                     TKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          148 a           84 c           75 g          133 t
ORIGIN      
        1 ctatactagc caaagagcca cgtatagagc ggtttgttcc gtcttatttc ctaatggtga
       61 ctttcctagt aggagtcgat tcactcgctt aagttcaaac ttagcttaca ctatcaagat
      121 tattcgatac tttttcatca agaagctcac caaaggtgaa ctagtcggaa ttatagatag
      181 ttttcctagt ccattatgta aaccagttag aaatagacaa gcaaaactat tgaatcaaat
      241 agccaaagtt ggctataact caacaaaaaa atcttatttt tatggtctta aaattcatat
      301 gatcgttact aagactggct ttccgattac ttactcaatc acgaatccag gtgtccatga
      361 cgtgaaagtg ttagagactt tatcggaaga agcgaatctt cccaatatcc taggggacaa
      421 aggatatatt agccataaaa
//
LOCUS       DADGHT010000279          423 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.287, whole genome shotgun sequence.
ACCESSION   DADGHT010000279 DADGHT010000000
VERSION     DADGHT010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.287"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>423)
                     /locus_tag="JX887_002969"
     rRNA            complement(<1..>423)
                     /locus_tag="JX887_002969"
                     /product="16S ribosomal RNA"
BASE COUNT           85 a          132 c           98 g          108 t
ORIGIN      
        1 gttgagccgg gggctttcac atcagactta agaaaccgcc tgcgctcgct ttacgcccaa
       61 taaatccgga caacgcttgc cacctacgta ttaccgcggc tgctggcacg tagttagccg
      121 tggctttctg gttagatacc gtcaagggat gaacagttac tctcatcctt gttcttctct
      181 aacaacagag ttttacgatc cgaaaacctt cttcactcac gcggcgttgc tcggtcagac
      241 tttcgtccat tgccgaagat tccctactgc tgcctcccgt aggagtttgg gccgtgtctc
      301 agtcccaatg tggccgatca ccctctcagg tcggctatgc atcgtggcct tggtgagccg
      361 ttacctcacc aactagctaa tgcaccgcgg gtccatccat cagcgacacc cgaaagcgcc
      421 ttt
//
LOCUS       DADGHT010000280          421 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.288, whole genome shotgun sequence.
ACCESSION   DADGHT010000280 DADGHT010000000
VERSION     DADGHT010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.288"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            188..385
                     /locus_tag="JX887_002970"
     CDS             188..385
                     /locus_tag="JX887_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258869.1"
                     /translation="MKFICLSCGEKESIPMDVVKFLDDADIANDPNNPPQFTCEKCGK
                     EMYPEYYRNALGIEFKISDVQ"
BASE COUNT          164 a           57 c           95 g          105 t
ORIGIN      
        1 tatgaattcg ttgggatgag tgtgcgcaaa aatggacggt tagttattaa atatgcgaaa
       61 gataaccatg caaagcggtt tatgcgagag gagaatcgaa aaattgacca aaaagaattc
      121 aggcaacagt atgaagaaga aaaagaaaaa acttttaaag caattcgctg ggattgggaa
      181 cgccaacgtg aaatttatat gtctaagttg tggtgaaaaa gaatcaatcc caatggatgt
      241 agtaaaattt ttagatgatg cagatattgc aaatgatccg aacaatcctc cccaatttac
      301 ctgtgaaaaa tgtgggaagg agatgtatcc agaatattat agaaacgccc ttggaataga
      361 gtttaagatc agtgatgttc aataagaagg ttaatcatac aaaaagtcca ccggagaatt
      421 c
//
LOCUS       DADGHT010000281          419 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.289, whole genome shotgun sequence.
ACCESSION   DADGHT010000281 DADGHT010000000
VERSION     DADGHT010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.289"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..395
                     /locus_tag="JX887_002971"
     CDS             <1..395
                     /locus_tag="JX887_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAX1258870.1"
                     /translation="KQGFTDIINGQTPQTPVVEESTQQATTTTTQSTSSSGISNWEAA
                     KETVLNNKALWIYESPDKNEANTNIIESTQYRKDLMQDENGEFYPVDISTDDIGNTVM
                     NGGKQFRVYTDGRISQRIGMTNNFQMIK"
BASE COUNT          179 a           59 c           66 g          115 t
ORIGIN      
        1 taaaacaagg atttacagat atcattaatg gacaaactcc ccaaacacca gtagtagaag
       61 aatctactca acaagcaaca actacaacga cacaatctac aagtagttca ggaatttcaa
      121 attgggaagc tgctaaagaa actgtactaa ataataaagc gttatggatt tatgagtctc
      181 cagataaaaa tgaagcaaat actaatatta ttgaatccac ccaatataga aaagatttaa
      241 tgcaagatga aaatggagaa ttttatccag ttgatatttc tactgatgat attggaaata
      301 cggtaatgaa tggaggaaaa caattccgtg tttatacaga tggaagaatt tctcaacgta
      361 ttggaatgac taacaatttt caaatgatta aataattgaa aatattattt atcaaagaa
//
LOCUS       DADGHT010000282          386 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.290, whole genome shotgun sequence.
ACCESSION   DADGHT010000282 DADGHT010000000
VERSION     DADGHT010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.290"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>386
                     /locus_tag="JX887_002972"
     CDS             <1..>386
                     /locus_tag="JX887_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1258871.1"
                     /translation="CTNPEEVEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQ
                     ALNELRIREMNELRKAGQKSQAEKLKKNWRFLLKNRASINHYEYKTWKSFRAPKYPFL
                     TEAMMIDRLLEFSAPLKEAYPFFHELV"
BASE COUNT          129 a           80 c           78 g           99 t
ORIGIN      
        1 tgcaccaatc cagaagaagt agaattctta gtcacagaca tgaacgccgc ttacttccag
       61 cttaccaaac gtgttctgcc aaatgcgaaa gtagtgattg atcggtttca tattgtcaaa
      121 cacatgaatc aggcactcaa tgagttgcgt atccgtgaaa tgaatgagct tcgtaaagca
      181 ggacagaaaa gtcaggcaga aaaactgaaa aagaactggc gctttctgct aaaaaatcgt
      241 gcaagcatca accattatga gtacaaaaca tggaaaagtt tccgagcacc aaaataccca
      301 tttctcactg aagcaatgat gattgatcga ttgcttgagt tttctgcgcc tctaaaggag
      361 gcgtatccct tttttcatga attagt
//
LOCUS       DADGHT010000283          370 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.291, whole genome shotgun sequence.
ACCESSION   DADGHT010000283 DADGHT010000000
VERSION     DADGHT010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.291"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(44..>370)
                     /locus_tag="JX887_002973"
     CDS             complement(44..>370)
                     /locus_tag="JX887_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1258872.1"
                     /translation="GKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVE
                     FVHQYQFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSD
                     TSGEAA"
BASE COUNT          102 a           91 c           66 g          111 t
ORIGIN      
        1 atcctcggat ctgattttct ccggcagaag cacaatcatt caattacgct gcctctccag
       61 aggtatcaga tccgcgctca ttatcaagga ttcgcttcgc caatctctgt tgtcgaattt
      121 ggatcggtgt ttcatacgcc aacgtgccat gtaagcgtag atagttccac caatgcacat
      181 aatcaaacaa ttctagacgt agctgtgcca gtgtctcaaa ttggtattga tgcacgaatt
      241 ctactttgac agatttatag gttgattcca caacggcatt atcatacgga caacccttcc
      301 tactcaatga acgagtaatt ccaaaaccat tcagaatctc atgaatggtt tggttatcaa
      361 attcctttcc
//
LOCUS       DADGHT010000284          358 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.292, whole genome shotgun sequence.
ACCESSION   DADGHT010000284 DADGHT010000000
VERSION     DADGHT010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.292"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..262)
                     /locus_tag="JX887_002974"
     CDS             complement(<1..262)
                     /locus_tag="JX887_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258873.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQ"
BASE COUNT          102 a           69 c           50 g          137 t
ORIGIN      
        1 tttgttgcgt gtgttccacc aatttttctg tatgtgtatc taatctttca tcgtgtttct
       61 ttagttcttc atgaatcatc aatcgatctg atttgctcga ttctaaatct ttagtcagca
      121 aatctaaatt gtggcttact tttgaaagag tctcagtaat tttcgagaaa gatgcagcaa
      181 tcggtctaat tactaataaa atcaaagaaa cgatagcggt tattgatcct gctatcattc
      241 cccattcccc taaattaatc atgtgacaac tcctttacct taaataaaaa cgcatcaatt
      301 aagatgcgct cttatcttta ttaatgattt tatctgcttc ttcgtctgta atgcataa
//
LOCUS       DADGHT010000285          343 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.293, whole genome shotgun sequence.
ACCESSION   DADGHT010000285 DADGHT010000000
VERSION     DADGHT010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.293"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          112 a           65 c           56 g          110 t
ORIGIN      
        1 ctgttctaac attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag
       61 ctctcaacag aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt
      121 ttttgttatt tgcgctttca cttttcggaa taaataatgt gtatttatat ggaataaata
      181 aaaaaagagg tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca
      241 actcctcggt cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct
      301 ctttgtgact cagagtgaaa cggcaggctc acgacctctt tct
//
LOCUS       DADGHT010000286          330 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.294, whole genome shotgun sequence.
ACCESSION   DADGHT010000286 DADGHT010000000
VERSION     DADGHT010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.294"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          127 a           54 c           45 g          104 t
ORIGIN      
        1 ctttttcgtt gctttgctca taaaaatctg catattcatc actaatattt tttctaataa
       61 attcttccat cataaagatc acctcgaaaa gagtatacga acaaacgttc tttttgtaaa
      121 ggtggaattt attatactaa ataaataggt gaacaagtac ttgtgccaaa ttatgtgcca
      181 aaaaaaatcg aatttaataa aacacaaaca aaaagaaatc ctattatgat aacatttctt
      241 ataataacaa acacaacaga agacgtgtaa tagttagtca ggaacgtaca aataacccct
      301 gtatcctttg cggtacaggg ggttattttg
//
LOCUS       DADGHT010000287          321 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.295, whole genome shotgun sequence.
ACCESSION   DADGHT010000287 DADGHT010000000
VERSION     DADGHT010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.295"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>321)
                     /locus_tag="JX887_002975"
     CDS             complement(<1..>321)
                     /locus_tag="JX887_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAX1258874.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSL"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DADGHT010000288          320 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.296, whole genome shotgun sequence.
ACCESSION   DADGHT010000288 DADGHT010000000
VERSION     DADGHT010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.296"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(34..270)
                     /locus_tag="JX887_002976"
                     /pseudo
     CDS             complement(34..270)
                     /locus_tag="JX887_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           99 a           49 c           55 g          117 t
ORIGIN      
        1 agaaggactg accttctgtc tcagattttt ttgttatttc acttgaatca attgattgat
       61 caaaaaaatc ctgattttca tgttctcaaa tgatttaaat ccataagata atcgtttcag
      121 tgtcttgata tggggaatct tggcctctat tttgccatta gaatacgggt aaatcatagc
      181 attgtaaata ccttcttcat acgttaaaag gttttgaagt ttcgtgcgaa gttgtgcatc
      241 aagtgtttca ggaagatttt ttaataacgc cgtttgtata attaagcgag acaaataaaa
      301 aagccattta tgttacactc
//
LOCUS       DADGHT010000289          319 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.297, whole genome shotgun sequence.
ACCESSION   DADGHT010000289 DADGHT010000000
VERSION     DADGHT010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.297"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>319
                     /locus_tag="JX887_002977"
     CDS             <1..>319
                     /locus_tag="JX887_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258875.1"
                     /translation="NMRLEDLFRLAEDDKYRFEVLKIQKNELLNKLYPENAIKAHFGD
                     ANHMYSWFIPKRFRGKINAGDQVKVLNRNSTDVVMITDIYVEDEDIIKYMKPVIKLVN
                     KNKG"
BASE COUNT          133 a           29 c           62 g           95 t
ORIGIN      
        1 aaaacatgcg tttagaagat ttatttagat tagcagaaga tgataagtat agatttgaag
       61 ttttgaaaat tcaaaagaat gaactattga ataagttata tcctgagaat gcgataaaag
      121 cacattttgg tgatgctaat catatgtata gttggttcat tcctaaaaga tttagaggga
      181 aaatcaatgc tggagatcaa gtgaaagtac tcaatcgaaa tagtacagat gtcgtaatga
      241 taacagatat ctatgtagaa gatgaagata taatcaaata tatgaagcct gtgataaaac
      301 ttgttaataa aaataaagg
//
LOCUS       DADGHT010000290          313 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.298, whole genome shotgun sequence.
ACCESSION   DADGHT010000290 DADGHT010000000
VERSION     DADGHT010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.298"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>313
                     /locus_tag="JX887_002978"
     CDS             <1..>313
                     /locus_tag="JX887_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAX1258876.1"
                     /translation="TTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGL
                     VLLGNGKAIYFGDLDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAW
                     R"
BASE COUNT          106 a           42 c           73 g           92 t
ORIGIN      
        1 gaacaactga ttctgttggt aatccttttc ctggggcttc tactccaacc cctattgaag
       61 ataattcttt agttattcgt acaaatggag acggcaaata tattttgatt tctcctaaag
      121 taggaaaagg attagtttta ttaggaaatg gtaaagcaat ttattttgga gacttagatg
      181 tacaaggaaa acttacagtt aaaggaaaag aaataattcc tggacaaggt ggtggtccat
      241 cgggaggtgg agaatctact ggtgggtatc ctagtgaatt aaaaacagat gcagaaaaga
      301 gagcttggag aat
//
LOCUS       DADGHT010000291          303 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.299, whole genome shotgun sequence.
ACCESSION   DADGHT010000291 DADGHT010000000
VERSION     DADGHT010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.299"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          107 a           33 c           48 g          115 t
ORIGIN      
        1 gaggactacc tgtattagtc ctcttttttg accagatttt gaccagtcta ttttacattc
       61 taatatattc atatgagcta attttatgat taaatggtaa gtttttcctt gtttgtttta
      121 gtttaaacta gtgtgtaatt caaaaatcta tatggaagga tctgtggggt aaatcattat
      181 acaaaagtaa aattttactt attaacaggc tgtagaaata taaaaaagaa ctaaaattta
      241 actaaattat gtgctattct taaggaaagc caagtgtatg agaaagtttc tgagaatata
      301 att
//
LOCUS       DADGHT010000292          302 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.300, whole genome shotgun sequence.
ACCESSION   DADGHT010000292 DADGHT010000000
VERSION     DADGHT010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.300"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>302
                     /locus_tag="JX887_002979"
     CDS             <1..>302
                     /locus_tag="JX887_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HAX1258877.1"
                     /translation="EDIFAYILEQAVKAGFVTEDNLYLDSTHIKANANKHKFTKEMTH
                     DEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVKGER"
BASE COUNT          117 a           48 c           68 g           69 t
ORIGIN      
        1 tgaggatatt tttgcctata ttttagaaca agcagttaaa gcaggttttg taacagagga
       61 taatttgtat ctggattcta cccacatcaa agctaacgcc aataaacata agtttacgaa
      121 agaaatgacc catgatgaag cgaaagccta tcaggatgaa ttagaagatg agatcaatcg
      181 tcaacgaata gaggctggaa aacgcccttt tactttggac ttagaaaagg aagtgaagct
      241 gaaagaaaga aaaataagta aagctgatcc ggaaagcggc tactacgtca aaggcgaacg
      301 ag
//
LOCUS       DADGHT010000293          293 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.301, whole genome shotgun sequence.
ACCESSION   DADGHT010000293 DADGHT010000000
VERSION     DADGHT010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.301"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           97 a           50 c           45 g          101 t
ORIGIN      
        1 taccatattt ttgaaaaaaa gtgagaaaaa aggcttacaa ttggagtggt agttaattag
       61 tgacttattt ttgattttat agcactgata ctataaaata tagatatcat catattacac
      121 aatcttaata ctaacttaaa aaatatctcc tttcacaagt atggtgataa aattcgttcc
      181 gggctacctt tttaggtagc ctactttaat ctttatacct ttctggatca acgaaagtat
      241 actttatata gtcataacgc cgatgatcgc tacgtgcgtc cggcacgtca gtc
//
LOCUS       DADGHT010000294          286 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.302, whole genome shotgun sequence.
ACCESSION   DADGHT010000294 DADGHT010000000
VERSION     DADGHT010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.302"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>286
                     /locus_tag="JX887_002980"
     CDS             <1..>286
                     /locus_tag="JX887_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAX1258878.1"
                     /translation="KKETIVRFEQYNHMPLVTRLKKQRYTCKNCRTHWTAQSYFVRLS
                     HSIADHVRYKIASLLTEKVSLSFIAKSCQVSLTTVTRTLKEFKSYLPKPSK"
BASE COUNT           90 a           57 c           49 g           90 t
ORIGIN      
        1 aagaaggaaa cgattgtccg ttttgaacaa tacaatcata tgcctttggt tacgcgccta
       61 aaaaagcaac gctatacctg taaaaactgt cgtacccatt ggacggctca aagttatttt
      121 gtccgactca gccattcaat cgcagatcat gttcgatata aaattgcttc tttactgact
      181 gaaaaagtat ctttgtcttt tattgcgaaa agttgtcagg tatctttgac taccgttact
      241 cgtacattga aagagtttaa aagctattta ccaaagcctt ctaaga
//
LOCUS       DADGHT010000295          270 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.303, whole genome shotgun sequence.
ACCESSION   DADGHT010000295 DADGHT010000000
VERSION     DADGHT010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..270
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.303"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..249)
                     /locus_tag="JX887_002981"
     CDS             complement(<1..249)
                     /locus_tag="JX887_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAX1258879.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKR"
BASE COUNT           67 a           51 c           48 g          104 t
ORIGIN      
        1 tcttttttca atgtattctt tttcctcagc aggaaaaatg atttcggttc tcccacaacg
       61 tcgcttattt tctttgtatt gttcaaagta ttcaagtgct gttccaccac atttgagaaa
      121 gttatagaca ttgtaaattg tttggcgtcc acgtttaagc tgcttcgcaa cgatagcaac
      181 cggagtttct tgatgaaaat atgcttctat cattacaagc tcgtttggtg taagatgggt
      241 ataagtcatt tatgttcact ctccttgtat
//
LOCUS       DADGHT010000296          260 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.304, whole genome shotgun sequence.
ACCESSION   DADGHT010000296 DADGHT010000000
VERSION     DADGHT010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..260
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.304"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          108 a           34 c           34 g           84 t
ORIGIN      
        1 aactaatcag aatcgtacaa atatttaata accaaatata tagaacataa cttaatatta
       61 agttatttga aattccataa aaaacgactg caggaattat tgtaagaaaa ggataaaaat
      121 agttcagtcc atctccataa ttgttaaatg ttgtatagtt gattggccct tcaaaaatag
      181 aagataaccc tttgattcgt gaaagatgaa aagataaatc acctgttgta taaatttctt
      241 gagcatttct cataaaattt
//
LOCUS       DADGHT010000297          252 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.305, whole genome shotgun sequence.
ACCESSION   DADGHT010000297 DADGHT010000000
VERSION     DADGHT010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.305"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(32..>252)
                     /locus_tag="JX887_002982"
     CDS             complement(32..>252)
                     /locus_tag="JX887_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAX1258880.1"
                     /translation="NKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIITGF
                     GAFLGSVLGVSNRTYKMFSAESEEGGNK"
BASE COUNT           73 a           61 c           41 g           77 t
ORIGIN      
        1 aggctcatcg cagtaatagt aattttcttt ttcatttgtt tcctccttct tcgctttcag
       61 ccgagaacat tttgtaggtt cgatttgata cacccaacac actccctaaa aacgcgccaa
      121 aaccagtaat gatgacaaca cagatatctg tgtactgcca attgagcgct ttaccaacta
      181 accccacgaa agtagctagt gcgggaataa ttaccagtgc gaaccatttt agtacttcga
      241 acgttttatt at
//
LOCUS       DADGHT010000298          243 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.306, whole genome shotgun sequence.
ACCESSION   DADGHT010000298 DADGHT010000000
VERSION     DADGHT010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.306"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>243
                     /locus_tag="JX887_002983"
     CDS             <1..>243
                     /locus_tag="JX887_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258881.1"
                     /translation="SDADKYNPEGQKVTTELNKEPDASEGIKNKEDLPKDTKYTWKEK
                     VDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRS"
BASE COUNT           99 a           33 c           56 g           55 t
ORIGIN      
        1 atctgacgct gacaaatata atcctgaagg tcaaaaagtg actacagaat tgaataagga
       61 accagacgca tctgagggaa ttaagaacaa agaagattta ccaaaagata ctaagtatac
      121 ttggaaagaa aaagtagatg ttagcgcagc tggaaataaa aaagggactg ttgtagtgac
      181 atatccagat ggatcatctg atgaagttga agtagatgtt acagtgacag acaatcgttc
      241 tga
//
LOCUS       DADGHT010000299          240 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.307, whole genome shotgun sequence.
ACCESSION   DADGHT010000299 DADGHT010000000
VERSION     DADGHT010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..240
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.307"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..227)
                     /locus_tag="JX887_002984"
     CDS             complement(<1..227)
                     /locus_tag="JX887_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /protein_id="HAX1258882.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGA"
BASE COUNT           97 a           48 c           22 g           73 t
ORIGIN      
        1 attgctccaa tcagtagcca agaaaaacgc attttaaaaa aatttttctt tataaaaacc
       61 tcatacaaaa ctataattcc accccaagca aaagctattt tcatcgggat attagttaca
      121 ttaaaagtac taggcataaa ataaagcaga caaatgatta aatttattac tcgaaacgca
      181 tctcgactta ataaactctt ctctaaaaca ggtactattc tattcatcta tatttccaac
//
LOCUS       DADGHT010000300          235 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.308, whole genome shotgun sequence.
ACCESSION   DADGHT010000300 DADGHT010000000
VERSION     DADGHT010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..235
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.308"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>235)
                     /locus_tag="JX887_002985"
     CDS             complement(<1..>235)
                     /locus_tag="JX887_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAX1258883.1"
                     /translation="PRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVK
                     GLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT           69 a           45 c           36 g           85 t
ORIGIN      
        1 atatcctaaa gaatatctca aagttccttc aaaacgtcgt tgtgctcgac ttaatagaac
       61 actgtaagcc agtaatatgc tttcaaatct actctctagc cctttaacag aacgtgagtt
      121 gaaattttga caacctaatt tttctaagga agaaaaaaca gtctcaactg tttttctttg
      181 ttttccaagt aagctgtggt ctagtttttc tgatttatcc atgtttttac gtggc
//
LOCUS       DADGHT010000301          232 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.309, whole genome shotgun sequence.
ACCESSION   DADGHT010000301 DADGHT010000000
VERSION     DADGHT010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.309"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           79 a           35 c           45 g           73 t
ORIGIN      
        1 gagaaaaagc atggaatgcg ctgcatcagg tatcgaggct tagaaaaaaa tcaggtgcat
       61 acgatgcttg tttttgccga aatgagtctg aaaaaattgg tcacttagca gtgggagcat
      121 atgtcttcat attttttatt atacaaaaat agacaaaagt atcagtctac actcttagta
      181 aagaggaaac tgatactttt gtctacagta tgatatttct tacatctact tt
//
LOCUS       DADGHT010000302          230 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.denovo.310, whole genome shotgun sequence.
ACCESSION   DADGHT010000302 DADGHT010000000
VERSION     DADGHT010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.denovo.310"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           85 a           28 c           28 g           89 t
ORIGIN      
        1 accttactat tttttatata agttttttag aataacaaaa cgtagttttc cacaaataaa
       61 tgatccatca aagtgtttca cgacttaaga aaacataatt ttcaaaaata agtttatttt
      121 ttaatgaaaa aaatagttgg atatgtaact ttaagtgatt gctgtgaaac aaaaagttga
      181 ttttatcttg aaattaggta aagaatttct tgctccgccc attttttctt
//
LOCUS       DADGHT010000303        14161 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.guided.073, whole genome shotgun sequence.
ACCESSION   DADGHT010000303 DADGHT010000000
VERSION     DADGHT010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14161
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.guided.073"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1598
                     /locus_tag="JX887_002986"
     CDS             <1..1598
                     /locus_tag="JX887_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HAX1258884.1"
                     /translation="AAAGMTVEEYAAAGYEAPQQDTFSIYQLRGGEETRDYRFEPYER
                     LQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNIDHPADFRGHSLSVSDVVVLHQN
                     GQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNENMIDGIINNTPPEPQPEEPEQL
                     SFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAARRAKEAMSFSDYRPGSATAEYR
                     HYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLAENMNKGYEITARVPSVLIAGP
                     SNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGMGGISADDPQAVSKLEKKLEKL
                     EASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKADMASGWHYEKKPFQSWQLSNNN
                     AEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVANRLQIFFEGKPDAAVRDELKS
                     NGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEKPSALQLAARREKEKPSIRAQL
                     NAAKTEQAKQPPAREKSKGLEVE"
     gene            1599..2543
                     /locus_tag="JX887_002987"
     CDS             1599..2543
                     /locus_tag="JX887_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258885.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            2547..2750
                     /locus_tag="JX887_002988"
     CDS             2547..2750
                     /locus_tag="JX887_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258886.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMLVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(3050..3286)
                     /locus_tag="JX887_002989"
     CDS             complement(3050..3286)
                     /locus_tag="JX887_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAX1258887.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(3469..3840)
                     /locus_tag="JX887_002990"
     CDS             complement(3469..3840)
                     /locus_tag="JX887_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258888.1"
                     /translation="MSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECICVQSI
                     SYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAACSKRM
                     RRRKEAERQRKRYWKPTHLEL"
     gene            complement(3837..5165)
                     /locus_tag="JX887_002991"
     CDS             complement(3837..5165)
                     /locus_tag="JX887_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAX1258889.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(5126..5455)
                     /locus_tag="JX887_002992"
     CDS             complement(5126..5455)
                     /locus_tag="JX887_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002566656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAX1258890.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(5713..6084)
                     /locus_tag="JX887_002993"
     CDS             complement(5713..6084)
                     /locus_tag="JX887_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1258891.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            6229..6414
                     /locus_tag="JX887_002994"
     CDS             6229..6414
                     /locus_tag="JX887_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAX1258892.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            7357..8016
                     /locus_tag="JX887_002995"
     CDS             7357..8016
                     /locus_tag="JX887_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HAX1258893.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            8019..9362
                     /gene="vanS"
                     /locus_tag="JX887_002996"
     CDS             8019..9362
                     /gene="vanS"
                     /locus_tag="JX887_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAX1258894.1"
                     /translation="MERKGIFIKVFSYTIIALLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQAQSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            9533..10339
                     /gene="vanY"
                     /locus_tag="JX887_002997"
     CDS             9533..10339
                     /gene="vanY"
                     /locus_tag="JX887_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-B/VanY-G family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HAX1258895.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGRR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            10357..11184
                     /gene="vanW"
                     /locus_tag="JX887_002998"
     CDS             10357..11184
                     /gene="vanW"
                     /locus_tag="JX887_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HAX1258896.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGEPFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            11181..12152
                     /locus_tag="JX887_002999"
     CDS             11181..12152
                     /locus_tag="JX887_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HAX1258897.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            12145..13173
                     /gene="vanB"
                     /locus_tag="JX887_003000"
     CDS             12145..13173
                     /gene="vanB"
                     /locus_tag="JX887_003000"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HAX1258898.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAACMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGTFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYPRMMAAAGITLPALIDS
                     LITLALKR"
     gene            13179..13787
                     /locus_tag="JX887_003001"
     CDS             13179..13787
                     /locus_tag="JX887_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HAX1258899.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
BASE COUNT         3671 a         3365 c         3724 g         3401 t
ORIGIN      
        1 ccgccgcagc cggtatgacc gtggaggaat acgcggcggc tggctatgaa gcaccccaac
       61 aggacacctt ttccatctac cagcttcgag gcggggagga aacccgcgac tatcggtttg
      121 agccatacga gcgtttacag gccgcagggc tggccgtgga cagtgccaac tatgaccttg
      181 tttatacggc accgctggat aaaagcacgt ctttggagga tatttaccgc acattcaaca
      241 tcgaccaccc ggcagatttt aggggacaca gcctttccgt ttccgacgtg gtggtgctgc
      301 accagaatgg acaggacacc gcccactatg tagacagctt cggctatatg gaagtgccgg
      361 agtttttgcg ggaaaatccc ctgcgtaccg ccgaactgtc tacggagcag aacgaaaaca
      421 tgattgacgg cattatcaac aatacgccgc ccgaaccgca gccggaggaa cccgaacagc
      481 tatcttttga ggatgtggca gttgcttccg gccagacaca ggaggaaccc ccggaggctg
      541 cgcccccgca aacggctgtc cgctattatc ccatcaatga gggagccgcc cgccgcgcca
      601 aggaagccat gagcttttct gactaccggc ccggcagcgc cacggcggaa taccggcact
      661 atgtcgatca ggccgtggaa attgcggagc gccagaaaaa gcgtgtggag ccagagtatc
      721 acgaaaagat agacagcctc cttgacacct acgcccgcaa gctggccgag aacatgaata
      781 agggctatga gattaccgcc cgcgtcccct ctgtcctgat tgccgggccg tccaatttcc
      841 cggtacgggc gaaagaaaag cagaacgccg ccagtgaccg caacatggag gaatttcagt
      901 acattcaggg cttgcttgac aaaatccgca gcaccggcat gggtggtatc agcgccgacg
      961 atccgcaggc cgtttccaag ctggaaaaga aactggaaaa gctggaagcg tcgcaggagt
     1021 tgatgaaggc cgtcaatgcc tactaccgca agcatgggac gctggacgga tgcccccatc
     1081 tgaccgaaag aggcattgaa aacctgaaag cggatatggc gtcgggctgg cactatgaga
     1141 aaaaaccgtt ccagtcctgg cagctctcca acaataacgc cgagatacgc cggttaaagg
     1201 gccgcattga ggaattgacc cgccaaaagg aggcggccta tgtgggatgg gagtttgacg
     1261 gcggcactgt ggagatcaac cgggtggcca accgcctgca aatcttcttt gaggggaagc
     1321 cggatgctgc tgtacgcgac gagctgaaaa gcaacggttt ccgctggtcg cccaaggccg
     1381 gggcatggca gcggcagtta aacgacacca caatccgcgt cgctgaccgt atcaagtgca
     1441 tccagcccct ttccggcgaa aagcccagcg ccttacagct tgcggcccgc agggagaaag
     1501 aaaagccctc tatccgggcg cagctcaacg cggccaagac cgaacaggcc aagcagccac
     1561 cggcgcggga aaaatcaaag ggattggagg tagagtaaat gcagaagttt gaaaatgtgg
     1621 acgttctggc cgcgctggaa cagatcatgc ggcagaacac cgcgttttat caaagtgact
     1681 ttggcattga caaagacatt atcaggcggg atgccgccag cgatcaggcc gcagacaaga
     1741 ccctgctctg gatgtcccgg ccctccggga cgtactgttt ccgggaacgt gatgttttcc
     1801 tgaaagacac ccgacagtac aacacatgga aattttacgg ggagcagacc cgtgacaaga
     1861 tactggccta cgcggtggag ctgaccggca cacagggcgg cactatccgg ggcaatctct
     1921 atgagctgga ctatccgcag catttccggc acgtcattga aaccgcccag ccggtgagtg
     1981 tgaaccggct cttttatgag catggcaccc gtgacatccc ggagagccag cgttttgacg
     2041 gaagccctga ccgggtattg ggaaactttt tgtactatga ggcccagccc catgacccgg
     2101 ctgtgctgca ggaggcgcta cggacggagc agcacagccg ggggcgggcc gtccccggcg
     2161 atttcaaagt ccacgtcacc gctttgcatg acagccggat tgaaaccgag gcccggcgta
     2221 ttgtggacag cctgaaagat ctgtccgcgc ctaacagccc caataaaacg catttcatgg
     2281 tggagatctc cccgcacttt gcggcgattg cttccaccaa ggataatgac cggctctttg
     2341 ccatgctgcc ctataaatcc ctgtgtttta ccgggatgaa aggcaggcat ggcgtgtatg
     2401 ccgtgattaa ccgggacgag cgccgggatg tgagtattcg caggccccgg ccctctatcc
     2461 gcaagcagct atccgacagc aaacaggccg ccagcccaaa aaaggcggcg gccagaacca
     2521 aaaagaatga attggaggta taaggaatga tgcactttac cgtggaggaa gaaaacctga
     2581 tctgtatgta ccacaatgca gaccggcgca gaacgataaa caggctcacc gccgtcatgc
     2641 tggttatgga tggggatatg cgggcgcagg cccagcagac cctttccaag ctggaacgca
     2701 tgacggatgc cgactatgac ggccagaagt tccacttcac agacgaataa cgaacagcag
     2761 acgccgggcg cggcggccat gtggtcgctt gcgtccggcg tcttttcttt ttgcctattc
     2821 ctacgcattt agaacccggt attgtcgggg ataggatgaa gtattcgctt gcccctgcaa
     2881 acatgcggga gaagccttgc agcgggcggt tttcaatccc ttaaatgcgt aggttgcagc
     2941 tataattaga cccctgaaac agatatagcc gcgcagcggg tgtatctgtt tcaggggtgt
     3001 gcaggtgata gccgcaaagc ggcgtaagag ggtgcagccc tcttgccgtc tatctctgtt
     3061 ccagcgggaa gctcggcaat gcttccagca gtttcaggga aatgcgctgc cgtatatctt
     3121 cgtcaatgac tttcttcttt ttgccgtttg cctgtctgat ctccaccgtg gaaagctcgt
     3181 tgatgtagtc agcataatgg gccaacactt tttccgtggc ccacctctca ccggcaacgg
     3241 cggctttgat cgtttcatag tccagcagct tttcttgtcc gtccatcctg atacccccgt
     3301 cagactgatt ttttctatga taccatattc ggaagcatgg aaccagagaa aacggcgctt
     3361 ttctgctggt aaattctacg catttagaac agcacttcgg cggggatagg ataaaacacc
     3421 cacatacccc gctgaccatg ccggaaaagc cttgaaatat aagggctttt acagctctaa
     3481 gtgcgtaggt ttccagtatc ttttccgctg gcgctcggcc tctttgcggc ggcgcatccg
     3541 tttggagcag gccgcgcagt atttggcccg gttagacttc ggcgtgaacg tggccccgca
     3601 ctcacagcag cgtttcactt cgtcccggtc tttggtgatc tcggcataca gggccgcatc
     3661 cagcgggagg acagcggcct taaaccagcg gcacagaagc gaataggaaa tgctctgtac
     3721 gcaaatacat tcttcgccgt cgtccagcaa caggcagttg ccgtcacaat agttgcagca
     3781 ctcatgcgtc agcttccggg ccttgcgata ttgagggtaa ttcattcgtg gaatactcat
     3841 agctcttgcg tccattcctt tcccggcgtc atacgcaaaa tgccgtccac attctgcttg
     3901 atgatgccgt attcctgcat ctgctttttc gcttcgccgt acttctcata cagccgttcc
     3961 ttttcctcgg ccaatcgctt gtactcggct ttcagggcgt acagatcggg gagctttttc
     4021 acaccctgtc cctttagggc ctttgccgca gcttcataca aaatcaacgt gctttcatgc
     4081 tcacgccgga attttgcctt atccgctgca ttgcggtatt ccatagccac gggccagagc
     4141 tgcttgtagg tagaaatatt ctttatcagc accgccatat ccgcaagccg gtgttccata
     4201 gctttgaggg tagcggcggc ctcgtcgctg gcggcggtga tctcggccac tttgctttcc
     4261 aaatccgggt aggtgtctat cccatgttca gtcaggaaat tcaaagtctt tgcggcctgc
     4321 ttcaaattgt ggagcttcgc ccacctctca tagcctgccg actgctgggc cttaatgttg
     4381 ttttccagat caatccgcaa agaaatcccc ttgcgctctt tgggcgctct ggtgataacg
     4441 cggcctttga tacgctcttt gatggcttcc tcggtgtagg cttcccccaa tgtcttgcag
     4501 cgggtaaagc gttcctgtcc gggagcgcgg aaagaaataa actttcccgg cttgatctca
     4561 tagccttgcg cctgcatgag ccgcaggaaa tcatcaaaat cttttgcctg cgggatagcg
     4621 gcgtcaatgg ctgctttgag cttcgctttc cagctcgtcc ctttccgctg ggcgtcccac
     4681 tcggcatagc tcttgccctt actctggccg ggcttcacca cggacaatcc gttttccttg
     4741 cacagcctgt cgctggtgcg ccggatatag gcatagctct gtttgttgga aatgtacttg
     4801 cgctgattta ccatatccac ggcacagaaa ataatgtgat tgtggacgtg gcccttatca
     4861 atatgggtag tcagcacata gggatatttc ccttgcagca cttcctcggc aagctgcttc
     4921 ccgatctcat gggcctgttc cggcgtggct tcgccggggg caaaggattg tatcaggtgg
     4981 tggcccagat tattgccctt ttggtatgcc tgcgccagca gcatttcaaa ttcaatgtcc
     5041 gctgtttcat aagagcaggc aaaggaggcc accagcagct tgccgtcagt tttgtccggg
     5101 ttctcgatgt agtcaagggc ttttttcagc gttgacttga taggatgtat ctttgtaact
     5161 gccatatctg cgccagcgcc ccctttatat cctcgatgtc ctgtgcgtac accggcccca
     5221 taccgttcag cctctttgca atctgattga cgttgacgcc gatcttctgt atctcggcgg
     5281 tctgcgcccg gatgtcgctg gtgtccatgt tgacgatata gccgtcaatg agcatcttcc
     5341 gggcgtaggc tgaaaagttc ttcgtatgca gcagcgccat tttctgttca atcatagccc
     5401 gttcctccgg cgtcacaggg acgcgcagca cgatttttcg ctttctgttt gccatgcttc
     5461 accgtccttt ccattcaggg gtttggggat ttccccaaca agcaaaacgg acgcggcccg
     5521 gcagggacgg ggcaggccgt ttttccggga gtggctacac tccctatgct tgctacgtta
     5581 ctgtttctcc actaacaaga cgtttccaaa gccccaaact acccgcaaaa tagccctctg
     5641 gaaagaaaaa agtgcaaaaa aatagaagct acgctgtgca gctcccgcta aaagtaaaac
     5701 agaggatgcc agttacacat cctccgtttc attcttcttc ggcttttcaa ttagtatggc
     5761 gctgtcaatc gcgccctcga tgatcggcag gtattcttcg gggcagagtt tcagcttgtg
     5821 gctgaccctt tgccgcagtt cgctttcctc ccgcatgatc tccgggttaa agtagcgttc
     5881 cacaggaagc ccgcaggctt taataagctg tatgacaacc ggcagactgg gaatggcccc
     5941 gtcgttttcg atgttggcaa gatagcgcca gtcaatattt attttctctg ccattgcttt
     6001 gcgcgaaacg cgctttgctt gccgggccgc tttcacatcc gcgccgaaag tttcaaagcc
     6061 gggacaatct tcaatattcg ccatatcgca cctcccactt acattgtata tttcatactc
     6121 tgcccgtgga atgttggtat atgcaccttt cttaaagttt atatttcaca ttttgtttct
     6181 tttattcttc gagcaaaaga attataatgt accctgtgga ggtgtactat ggactacatg
     6241 acgttgaaag aggcaggcga gaaatggggt gtgcccccac gatggataaa ctactattgt
     6301 gctgcgggac gcatccccgg cgctgtaaag atggcgacga tctggctcat tcccaaaact
     6361 gcggaaaagc cgattgacag gcgtacaaag aaaggaaagg cggttactga atagtataat
     6421 gaaaccggcg cattttggat atggttttga agagagagaa agcatggtat tttgtcacgg
     6481 aaaaactata agatgataga tggcaggctg ctccagaccg ataaaaagta ttctcatctg
     6541 aaacagaaag aaaagattta cacatggatg tatgaagaag cgaaacttta tcatgacaga
     6601 aatggaaaat gcccgaaaca aagacgagga agctgctgct gtatcagccg tatatggtag
     6661 aattgaaaag gccggcatct ggattcttta tggtgaagtc tccagacatt ggataactgc
     6721 tggtctaatg cgcctttgag tatggggtga ttgattttaa taccggggag gtacggcttt
     6781 ttgaggaaaa tattctggga tttacatttg gcgattatta catttcctgt aactgcaagg
     6841 acacggatga tgaagatatg aggaatatag acttgctgat tttctactgt cttgaacggt
     6901 attaggactg aatctgctgc gcggagtgcg gcaagagcga ccggagggag tacacacagg
     6961 ccctgcctgt gtgaaaagcc ataccgcaag gtgcattcgc aaaaaagagg ccgcgcattt
     7021 tgctgaggct tggggtgtcc ccaacaagca aaacgagaac gccgcaggcg ggcaagtggt
     7081 ggatcagaat atccgtaaag gatattctga tccattgctt gccagtatta tcgggatgtt
     7141 ttgacaaccg ctgtaatcga aacatcccaa acattaagaa ggtgttaatt attattatct
     7201 tgatttaatt cgtttaaacc aataatatag atacatacac catgaaaaga agcgagtatc
     7261 ccaatgacgg atgattaaaa tccgaaaaga aatcgctttg aaactacagg gaaactacag
     7321 actgttatgt tatcttctta aaatggaggg atttttatgt cgatacgaat tctacttgtc
     7381 gaggatgatg atcatatctg taatacagta agggcgtttc tggctgaggc aggatatcag
     7441 gtggatgcct gcacagatgg aaatgaggca tacaccaagt tttacgaaaa cacttatcaa
     7501 ctggttattc ttgatattat gctgcccggt atgaacgggc atgaactttt gcgtgaattt
     7561 cgtgcgaaaa atgatactcc cattctgatg atgacagccc tgtcggatga cgaaaaccaa
     7621 atccgggcgt ttgatgcaga ggcagacgac tatgtaacaa agccattcaa gatgcagatt
     7681 ttactaaagc gggtggaagc cctgctgcgg cgcagcggtg cgctggcaaa ggaaatccgt
     7741 gtcggcaggc tgacacttct gccggaggat ttcacggtac tttgtgacgg tacagagctg
     7801 cccctgacac gaaaagaatt tgaaatcctt ttgctgctgg tgcagaacaa aggcagaacc
     7861 ttaacgcatg aaatcatttt gtcacgtata tggggatatg actttgaggg tgatggcagc
     7921 acagtccaca ctcatatcaa aaatttgcgg gccaagctgc cggaaaatat catcaaaacc
     7981 attcgcggtg taggataccg attggaggaa tcataataat ggaaagaaaa gggattttca
     8041 ttaaggtttt ttcctatacg atcattgccc tgctactgct tgtcggtgta acagcaacac
     8101 tgtttgcaca gcaatttgtg tcttatttca gagtgatgga attacagcaa acagtaaaat
     8161 cctatcagcc attggtggaa ctgattcaga atagcgatag gcttgatatt caagaggtgg
     8221 cagggctgtt tcactacaat aaccaatcct ttgagtttta tattgaagat aaagagggaa
     8281 gcgtactcta tgccacacca aatgccaata catcaaatag ttttagaccc gactttcttt
     8341 atgtggtaca tagagatgat aatatttcga ttgttgctca aagcaaggca ggtgtgggat
     8401 tgctttatca agggctgaca attcggggaa ttgttatgat tgcgataatg gttgtattca
     8461 gccttttatg cgcgtatatc tttgcgcggc aaatgacaac gccgatcaaa gccttagcgg
     8521 acagtgcgaa taaaatggca aacctgaaag atgtaccgcc gccgctggag cgaaaggatg
     8581 agcttggcgc actggctcat gatatgcatt ccatgtatgt caggctgaaa gaaaccatcg
     8641 caaggctgga ggatgaaatc gcaagggaac atgagttgga ggaaacacag cgatatttct
     8701 ttgcggcagc ttctcatgag ctaaaaacgc ccatcgcggc tacaagcgtt ctgttggagg
     8761 gaatgcttga aaatatcggt gactacaaag atcattctaa gtatctgcgc gaatgcatca
     8821 aaatgatgga taggcagggc aaaatcattt ccgaaatact ggagcttgtc agcctgaatg
     8881 atgggagaat cgtacccata gctgaaccgt tggacatagg gcgcacggtt gccgagttgc
     8941 tgcccgattt tcaaaccttg gcagaggcaa acaaccagcg gttcgtcaca gatattccag
     9001 ccgggcaaat tgtcctgtcc gatccgaggc tgctccaaaa ggcactatcc aatgtcatat
     9061 tgaatgcagt tcagaacacg ccgcagggag gcgaggtacg gatatggagt gagcctggtg
     9121 ctgaaaaatg ccgccttttt gttttgaaca tgggcgttca cattgatgat actgcgcttc
     9181 caaggctgtt caccccattc tatcgcattg atcaggcgca aagcagaaaa agtgggcgaa
     9241 gcggtttagg acttgccatc gtacaaaaaa cgctggatgc catgagcctc cagtatgcgc
     9301 tggaaaacac ctcggatggc gttttgttct ggctggattt accgctcaca tcaacattgt
     9361 aaatatttaa aacttaaatg attttgaccg acaggtataa ccctgccggt ctttttttgc
     9421 tgctacagga aaactacaga ctggctacag ggaaagtaca gatgcgcttg ccataataac
     9481 aatcgtacca gccacaaatc gtagttttat tgcaaaggag gcattcgatc aaatggaaaa
     9541 aagcaactat cattccaatg cggatcatca caaacggcat atgaaacaat ccgtggaaaa
     9601 gcgggctttt ctatgtgcgt tcattatttc gttcacagtc tgcacgctgt ttttggggcg
     9661 gagactggct tccgtattgg aggcaacaca gataccgccc atccctgcaa ctcatacagg
     9721 cagcagcact gacgtagtgg agaatttgga ggaaaacgct cttgccaccg ccaaagaaca
     9781 gggagatgaa caggaatgga gcctgatttt agtgaacagg cagaacccca tccccgcaca
     9841 gtacgatgtg gagcttgagc aactatcaaa tggtgagcgg atagatattc ggatttctcc
     9901 ctatcttcaa gatttgtttg atgccgcaag aactgatgga gtttacccga ttgtcgcatc
     9961 cggataccga acaacagaaa aacagcaaga aattatggat gaaaaaattg ccgaatataa
    10021 ggcgaaaggc tacacctctg cacaggctaa agcggaagca gaaacttggg tggccgtgcc
    10081 gggaacgagc gagcatcagc ttggtcttgc tgtggatatc aatgcggacg gaattcattc
    10141 aacaggcaac gaggtttata gatggctgga tgaaaacagc tatcgttttg gttttattcg
    10201 tcgctaccca ccagacaaga cagagataac cggtgtgagc aacgagccgt ggcattaccg
    10261 atatgttggc atcgaagctg ccacagagat gtacaaccaa ggggtttgcc ttgaggaata
    10321 tttaaaacca gaaaaatgag aaaaggatgt tatgttatgg acagaaaaag attgacacag
    10381 cgtttcccgt tcctgcttcc aatgagacgg gcgcagagaa aaatgtgctt ttatgcggga
    10441 atgagatttg acggctgtcg ctatgcgcag acgatagggg aaaaatcgct ttcccatttg
    10501 ctctttgaaa cggattgcgc attatacaac cacaataccg gatttgacat gatataccag
    10561 gaaaacaagg tgttcaactt aaagctggca gcaaagacct taaacggctt attgataaga
    10621 ccgggggaac ccttttcttt ctggtggctg gtacgccatg cggacaaaga taccccctat
    10681 aaagacggcc ttacggtgac caatggtaaa ctcaccacca tgtcgggcgg cggtatgtgc
    10741 cagatgagca atttactatt ttggatgttc ctgcatacgc cattgacaat tatccagcgc
    10801 agaggtcacg aagtaaagga gtttccagag ccaaacagtg acgagattaa aggggtggat
    10861 gcaaccattt cagagggctg gattgattta aaagtgcgaa acgataccga ctgcacctac
    10921 caaatatggg tgaccttaga tgatgagaaa atcatcggtc aggtgtccgc cgacaaagag
    10981 ccccaagcat tatacaaaat tacaaatggc agtatccagt atgtccgtga aagtggcggg
    11041 atttatgaat atgcccaggt taaacggatg caagttgcct taggtaccgg ggaaataata
    11101 gattgcaagc tgctttatac aaacaaatgc aaaatctgtt atcccctccc ggaaagtgtg
    11161 gatattcagg aggagaacca atgagaaaaa gtgtgggcat tactgttttt ggatgcgaac
    11221 aggatgaggc aaatgctttc cgcgctttat cgccggattt tcatattatc cctacgctga
    11281 ttagcgatgc gatatcggca gacaacgcaa aattggccgc tggcaatcaa tgcgttagcg
    11341 taggccataa gtccgaggtt tccgaggcga caattcttgc gctgagaaag gtcggggtaa
    11401 aatacatttc tacccgcagc atcggctgcg atcacattga tacgactgcc gccgagagaa
    11461 tgggaatctc ggttggcacg gttgcgtatt cgccggacag cgttgcggat tatgctttga
    11521 tgctgatgct gatggccata cggggtgcaa aacccaccat gcacgccgtg gcgcaacaag
    11581 atttcagatt ggatcgtatc cgggggaaag aactggggga tatgactgtg ggagttattg
    11641 gaaccggcca tatcgggcaa gcggtcgtca aaaggctgcg gggatttgga tgccatgtgc
    11701 tggcctatga taacagccga aaaatggatg cagattatgt ccagcttgat gagcttctaa
    11761 aaaacagcga tattgttacg ctccatgtgc cgctttgtgc ggatacccgc catctgatcg
    11821 gtcagaagca aattggagag atgaagcaag gcgcattttt aatcaacacc gggcgcggag
    11881 cgcttgtcga taccggggcg ctggtggagg cgttggaaag cggaaagctg ggtggtgcgg
    11941 cactggatgt gttggagggc gaggatcagt ttgtttatac cgattgctcg cagaaagtgc
    12001 ttgaccatcc ctttttgtcg cagcttttaa ggatgccgaa tgtgatcatc acaccccata
    12061 cggcgtacta cactgagcgt gtgctgcagg atactacaga aaaaacaatc aggaattgtc
    12121 tcaattttga aaggagttta cagcatgaat agaataaaag tcgcaatcat cttcggcggt
    12181 tgctcggagg aacatgatgt gtcggtaaaa tccgcaatag aaattgctgc gaacattgat
    12241 acggaaaaat tcgatccgca ctacatcgga attacaaaaa acggtgtatg gaagctatgc
    12301 aagaagccat gtacggaatg ggaagccgac agtctccccg ccatactctc cccggatagg
    12361 aaaacgcatg ggctgcttgt catgaaagaa agcgaatacg aaacacggcg tattgatgtg
    12421 gctttcccgg ttttgcatgg caaatgcggg gaggatggtg cgatacaggg gctgtttgta
    12481 ttgtctggta tcccctatgt gggctgtgat attcaaagct ccgcagcttg catggacaaa
    12541 tcactggcct acattcttac aaaaaatgcg ggcatcgccg ttcccgaatt tcaaatgatt
    12601 gataaaggtg acaagccgga ggcgggtgcg cttacctacc ctgtctttgt gaagccggca
    12661 cggtcaggtt cgtcctttgg cgtaaccaaa gtaaacggta cggaagaact taacgctgcg
    12721 atagaagcgg caggacaata tgatggaaaa atcttaattg agcaagcgat ttcgggctgt
    12781 gaggtcgggt gtgcggtcat ggggaacgag gatgatttga ttgtcggcga agtggatcaa
    12841 atccggctga gccacggtac cttccgcatc catcaggaaa acgagccgga aaaaggctca
    12901 gaaaatgcga tgattacagt tcccgcagac attccggtcg aggaacgaaa tcgggtgcag
    12961 gaaacggcaa agaaagtata tcgggtgctt ggatgcagag ggcttgcccg tgttgatctt
    13021 tttttgcagg aggatggcgg catcgttcta aatgaggtca ataccctgcc cggttttaca
    13081 tcgtacagcc gctacccacg tatgatggcc gccgcaggaa tcacgcttcc tgcactgatt
    13141 gacagcctga ttacattggc gttaaagagg tgataagtat ggaaaatggt tttttgtttt
    13201 tagatgaaat gttgcatggc gtccgttggg atgccaagta cgccacatgg gataacttca
    13261 caggaaaacc ggtggatggg tatgaggtga atcgcatcat cggcacaaag gccgtggcgt
    13321 ttgctctgcg cgaggcacaa atccatgcgg ctgcgcttgg ctatggcttg cttttatggg
    13381 atggatatcg gccaagaact gcggtggact gcttcctgcg ttgggcagcg caaccggagg
    13441 acaatctcac aaaagaaaaa ttttacccca atatagagcg agccgagttg attacaaagg
    13501 gttatgtggc ctcacaatcc agccatagcc gtggaagcgc aattgatctt acgctctacc
    13561 acctggatac aggggaactt gtttcaatgg gaagtaactt cgattttatg gacgaacggt
    13621 cgcatcatac agcaaaaggg ataggggatg cagaggcaca aaatcgaaga tgcttgcgta
    13681 aaatcatgga aagcagcgga tttcagtctt atcgctttga atggtggcac tataagttga
    13741 ttgatgagcc ataccccgat acctatttta attttgccgt ttcataatga aagtattggt
    13801 tttgtatcag attttggatt tgataaaatc tatgctggtc atggacaatc ttttactgga
    13861 aagtggttaa agcatctttt gtaatacatt gcaaattata gtattcaatc tgcccagcgg
    13921 cagaaaagaa aaaaaccgct gttgggcaga cctttcccac gcccattttg tattttgctg
    13981 gcggcggttt tgagaaatca aggccgccgt tcttttctgg cagcaaaagg tgtggcggcc
    14041 cataggagga tgccgctatg ctgttttgct attgccatgc tctaatccac ttccaccact
    14101 caaaaaaagc cttgcccctc catgaactga accccaaaag ttgaactatt taatggactg
    14161 t
//
LOCUS       DADGHT010000304         8729 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.guided.110, whole genome shotgun sequence.
ACCESSION   DADGHT010000304 DADGHT010000000
VERSION     DADGHT010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.guided.110"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..474
                     /locus_tag="JX887_003002"
                     /pseudo
     CDS             1..474
                     /locus_tag="JX887_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            986..1282
                     /locus_tag="JX887_003003"
     CDS             986..1282
                     /locus_tag="JX887_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HAX1258900.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            1283..1699
                     /locus_tag="JX887_003004"
     CDS             1283..1699
                     /locus_tag="JX887_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAX1258901.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            1719..3263
                     /locus_tag="JX887_003005"
     CDS             1719..3263
                     /locus_tag="JX887_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAX1258902.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            3406..3630
                     /locus_tag="JX887_003006"
     CDS             3406..3630
                     /locus_tag="JX887_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAX1258903.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            3645..4514
                     /locus_tag="JX887_003007"
     CDS             3645..4514
                     /locus_tag="JX887_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAX1258904.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            4495..5229
                     /locus_tag="JX887_003008"
     CDS             4495..5229
                     /locus_tag="JX887_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAX1258905.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            5262..6170
                     /locus_tag="JX887_003009"
     CDS             5262..6170
                     /locus_tag="JX887_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAX1258906.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            6167..6709
                     /gene="sat4"
                     /locus_tag="JX887_003010"
     CDS             6167..6709
                     /gene="sat4"
                     /locus_tag="JX887_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAX1258907.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            6802..7596
                     /locus_tag="JX887_003011"
                     /note="aph(3')-IIIa"
     CDS             6802..7596
                     /locus_tag="JX887_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAX1258908.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(7704..7892)
                     /locus_tag="JX887_003012"
                     /pseudo
     CDS             complement(7704..7892)
                     /locus_tag="JX887_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7872..8444
                     /locus_tag="JX887_003013"
     CDS             7872..8444
                     /locus_tag="JX887_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAX1258909.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPISLGFYEQNWYLIGFAG"
BASE COUNT         3049 a         1391 c         1910 g         2379 t
ORIGIN      
        1 gaatctttgc cgatttttcc tgatcgatac gattttgaag ttgcaaaaga taagggaaag
       61 cagtttaaaa ttgttgctga acttctcaaa aaggcaaata caattattgt cgcaacagat
      121 agcgacagag aaggtgaaaa tatcgcctgg tcgattatcc ataaagcaaa tgccttttct
      181 aaagataaaa cgtataaaag attatggatc aatagcttag aaaaagatgt gatccgaagc
      241 ggttttcaaa atttgcaacc aggaatgaat tactatccct tttatcaaga agcgcaaaca
      301 cgccaaattg ccgattggtt gatcggcatg aacgcaagcc ctttatatac cttgaattta
      361 caacaaaaag gcgtacaagg tacattttca ttaggacgtg tacaaacacc gactttatat
      421 ctcatttatc aacgccagga agcaatagaa aactttaaaa aagaaccttt tttcctgaat
      481 aattcatagt tttactaata gtctttccta acattgattt aatagtcttt aaagtattct
      541 gcttcatcac ccattaggtg atgaaaaaag aacccctttc tgatttagcg gacaaatact
      601 ttgacctaat ctcagaagat ataaaagaaa aaataataaa atatccgatt tatactttgt
      661 ataaagaact aaagtagtta gcaaatcatt tacagcaaat cactatgttc cacataccat
      721 tttacatact taccttatcc acgacacatg ttgagatagt atcgaagata aagaaagttg
      781 ctccatgttg tttttgcgag atggggaaat caaagccaca ttgacaacca tgatgaataa
      841 gcttgctttc agtcataagc taatcctaga accacttttc aagtcagtta gccaaatcga
      901 tgaagaaagc gaccgtgaaa gaatggacgc tattgataag ctaatggagc aactattgga
      961 agaacgcaat acccttattg cactgatgtc caaaggtttc ctagaacctg ctctttttaa
     1021 tcaggaacga aatgttttag atagtgagat taaaaatctt actaccgaaa aaacaaacct
     1081 ggtaacgaac tctgcgagtg gggttttgcg agcaaacgag ataaaggacc tcattaatta
     1141 tgtgtcagca gataatttta atggtgacta cacggaagaa ctatttgaag aatttgtagt
     1201 gaacatcatt gtaaattcca gggatgagct gacattcaat ttgaaatgcg gtctttccct
     1261 gaaagaaaag gtggtgagat aaatggcata tattccatat ggatacaaaa ttcaagatgg
     1321 agtggttact gtcgatgaaa aggcagcagg tcaagtaaag gtattctttg agaaatacat
     1381 atcaggacta tcccttacag tggctggcga acaggcaggt attgaaaaga cacattctgt
     1441 gatggggcgc attttgaaaa acgtcaacta ccttggaaat gatacgtatc cagcaattat
     1501 tgataaagag atatttgata aagctgaaga agttagagat aaacgtgcaa aggatttagg
     1561 acgagtggta gagcttgccg ctttcacctc tccccctccc aaagaacgat tcaaaatgaa
     1621 aaaggcagat aataagatgc cagtggatcc ttttgaacga gcagaatact tatacagtct
     1681 gatagaaagc gaggaataaa gtgacagaga aaaatataat ggttattcct gctcgtaaaa
     1741 gagtaggaag tacagccgca aaagaaaaga taaagaaact tcgtgttgct gcctattgcc
     1801 gtgtttctac agaaacagaa gaacaaaatt ctagctatga ggttcaggtc tcacactata
     1861 cagagtttat aaagaaaaat aatgaatggg agtttgctgg catctttgca gatgatggta
     1921 tctctggtac gaacactaaa aagcgtgacg aatttaatcg catgattgca gagtgtatgg
     1981 acggtaacat cgacatggtt attacaaaat ccatcagccg atttgcgcgt aacaccctag
     2041 actgccttca atacattaga cagctcaagg ataagaacat atcagtttat tttgagaaag
     2101 agaacatcaa caccacggat gccaaaggtg aggttttgct gactattatg gcatctttgg
     2161 cacagcagga aagccagagc ctttcacaaa acgttaagct tgggctacag taccgatacc
     2221 aacaaggaaa ggtgcaggtc aaccataagc gatttatggg ctacacgaaa gatgaagatg
     2281 gaaatttaac tattgtcccc gaagaagctg agattatcaa acgcatctac cgagaatacc
     2341 ttgagggtca gagtctagtg ggcattggtc gagcccttga aaaggatggt attttaacag
     2401 cagcgggaaa accaagatgg cgaccagaat cagttaagaa gatacttcaa aacgaaaaat
     2461 acatcggaga tgcccttctg caaaagactg tcacagtaga ttttctgacc aagaaacgag
     2521 tgaaaaatga agggcatgtt ccccaatatt atgttgaaaa tagccatgaa gcgattattc
     2581 ctaaagagtt atttttgcag gcgcaagaag aaattcatcg gagaagcaat atctacacag
     2641 gagaaggcaa gaacaaaaga atttacagta gcaagtacgc tttaagtgcc atcaccttct
     2701 gtggagattg tggcgatatt tatagacggg tctattggaa tatccacgga agaaaagaat
     2761 ttgtctggcg atgcgtgact agaatcgagc aaggtcctga agtttgtaag aaccgaaccg
     2821 taaaagaaga tgaactttat ggtgcagtaa tgactgcgat taataagcta cttgcaggtg
     2881 ggaacaatat gataaagaca ctggaagaga atattcatgc tgtgattggc gaaaccacag
     2941 aataccaaat ttcagagatt aacaactcac tagaggaaaa acaaaaagaa ctaatcaagc
     3001 tggcgaacaa gggtcaagac tatgaccact tagcagatga gattgatgag ctgagagaca
     3061 agcgacagat ccttttagta gaagatgcct ccctcagtgg cgagaacgag cgaatcaatg
     3121 agctgattga atttatccgc aagaacaaat tccgcacctt agaatatgat gataagcttg
     3181 taaggaagat aatccagagc gttacagtct atgaaggcca cttcgtcata gccttcaaat
     3241 ctggcatcga aatggaaata tgaaaaccag aagtaaatag cccatgactc tacagtagag
     3301 ttgtgggttt tcttttgctt gctgattata ataatatttt aataactatt gtgtttatca
     3361 accaaatggt ttataatatt cttagcgtaa acttggaggt gctgtatgac tacggcagaa
     3421 atgattaaag aactgtgtga gcaaatgaat ataagtgttt ccgaacttgc tagacgtatt
     3481 ggccagactc cacagaattt caataaaaaa ttacaacgag aaacagtaac cttggatgag
     3541 ttgaaggcca ttgctgatgt gctaggtgtc aagtttgtgc aggcatttat tttaccagat
     3601 ggagaagaaa taaaaatatc taacgaataa aggaggatgt ttatatggta ggtaatgtta
     3661 ttcaaatagt aacagagaaa ttatcatctt tgccttttat agaaggcatc gtattagggg
     3721 gctcacgtgc aagaggcacc catacagaaa attctgatat agatatcgga atctattaca
     3781 attcagactc atttgacctg acagcgatta atcaaattgc tacagagttg gatgatgaga
     3841 atagaaacaa ccttgttgta cctcccggag cgtggggtga ttgggttaat ggcggtggat
     3901 ggttagttat aaacgggtgt catgttgact tgatattacg tgatataaaa cgggtggaac
     3961 aaataatcaa agatacggag caaggaattg ttactgccaa ttatcagacc gggcatcccc
     4021 atggttatat aagtgctatg tatcgtggag aattagcgat tagtaaaata ctatatgcta
     4081 agaacgaaag cttatgcgaa ttaaaaaagc aggcagaaat ttaccctact gctctaaaga
     4141 aaagcttgat gaactttttt atatttgaag ctgaattctc tttaatgttt gtaaaagcaa
     4201 atgcgggggc agaggataaa tattatattg caggccatgt ttttcgtatt atttcatgct
     4261 taaatcaagt actatttgca tgtaataatg cttattgcat taacgaaaag aaagctataa
     4321 aactgcttga aacttttgaa tataaacctg aaaaatatgc cgaaagagtt aatcatattt
     4381 ttgaagtact cggtctttct ctttttgaat gctacgacat gaccgagaaa ctttataaag
     4441 aagtgaatga aattgtatcg gagataaata actttttaaa cgaggagagt tcagatgaaa
     4501 gaaaacaaat atgatgataa tatatttttt caaaaataca gtcaaatgag tcgctcgcag
     4561 aaaggactgg ctggtgcggg agaatgggag actttgaaaa agatgctacc tgattttaag
     4621 ggtaagcgtg tgcttgattt aggatgcggc tatggatggc actgtatata tgcgatggaa
     4681 aacggtgctt cctctgtagt aggtgttgat atttctcata aaatgctcga agtagcaaaa
     4741 ggaaaaaccc attttccaca gattgaatat gaatgctgtg ccatagaaga tgtggatttc
     4801 ccagaggaga gctttgatgt aatactaagt tcgcttgcgt ttcattatgt agcagactat
     4861 gagaatttaa taaaaaagat atataggatg ctgaaggctg gtggcaattt agtttttaca
     4921 gttgaacatc ctgtttttac tgctcatgga acacaagact ggtattataa cgaaaaagga
     4981 gaaatactgc atttcccggt ggacaattat tattatgagg gcaaacggac agctatgttt
     5041 ttggaagaaa aggttacaaa atatcataga acactgacca catatctaaa tacactgctt
     5101 tcaaatagtt ttataataaa tcagattgtg gagccacagc cgccagagaa catgatggat
     5161 attccgggga tggcggatga aatgcgacgc ccaatgatgc tgattgtatc ggcaaaaaag
     5221 aagatgtaat aatatagaaa aaataaacga ggagtatgta aatgagatca gaaaaagaaa
     5281 tgatggattt agtactttct ttagcagaac aggatgaacg tattcgaatt gtgacccttg
     5341 aggggtcacg cgcaaatatt aatataccta aagatgaatt tcaggattat gatattacat
     5401 attttgtaag tgatatagaa ccgtttatat ctaatgatga ctggcttaat caatttggga
     5461 atataataat gatgcaaaag ccggaggata tggaattatt cccacctgaa gaaaagggat
     5521 tttcctatct tatgctattt gatgattaca ataaaattga tcttacctta ttgcccttgg
     5581 aagagttaga taattaccta aagggcgata aattaataaa ggttctaatt gataaagatt
     5641 gtagaattaa aagggacata gttccgactg atatagatta tcatgtaaga aagccaagcg
     5701 caagggagta tgatgattgc tgcaatgaat tttggaatgt aacaccttat gttattaaag
     5761 gattgtgccg taaggaaatt ttatttgcta ttgatcattt taatcagatt gttcgccatg
     5821 agctgctgag aatgatatca tggaaggtcg gcatcgaaac aggctttaaa ttaagtgtag
     5881 gcaagaacta taagtttatt gaaaggtata tatccgagga tttgtgggag aaacttttgt
     5941 ccacctaccg gatggattcc tatgaaaaca tatgggaagc attatttcta tgccatcaat
     6001 tgttcagggc ggtatccggt gaggtggcgg aaaggcttca ttatgcctat ccggagtatg
     6061 ataggaatat aacaaaatat accagggaca tgtataaaaa atacactggt aaaaccggct
     6121 gcctggatag cacatatgcc gctgatatag aagagaggcg ggaacagtga ttacagaaat
     6181 gaaagcaggg cacctgaaag atatcgataa acccagcgaa ccatttgagg tgataggtaa
     6241 gattataccg aggtatgaaa acgagaattg gacctttaca gaattactct atgaagcgcc
     6301 atatttaaaa agctaccaag acgaagagga tgaagaggat gaggaggcag attgccttga
     6361 atatattgac aatactgata agataatata tctttactac caagacgata aatgcgtcgg
     6421 aaaagttaaa ctgcgaaaaa attggaaccg gtacgcttat atagaagata tcgccgtatg
     6481 taaggatttc agggggcaag gcataggcag cgcgcttatc aatatatcta tagaatgggc
     6541 aaagcataaa aacttgcatg gactaatgct tgaaacccag gacaataacc ttatagcttg
     6601 taaattctat cataattgtg gtttcaaaat cggctccgtc gatactatgt tatacgccaa
     6661 ctttgaaaac aactttgaaa aagctgtttt ctggtattta aggttttaga atgcaaggaa
     6721 cagtgaattg gagttcgtct tgttataatt agcttcttgg ggtatcttta aatactgtag
     6781 aaaagaggaa ggaaataata aatggctaaa atgagaatat caccggaatt gaaaaaactg
     6841 atcgaaaaat accgctgcgt aaaagatacg gaaggaatgt ctcctgctaa ggtatataag
     6901 ctggtgggag aaaatgaaaa cctatattta aaaatgacgg acagccggta taaagggacc
     6961 acctatgatg tggaacggga aaaggacatg atgctatggc tggaaggaaa gctgcctgtt
     7021 ccaaaggtcc tgcactttga acggcatgat ggctggagca atctgctcat gagtgaggcc
     7081 gatggcgtcc tttgctcgga agagtatgaa gatgaacaaa gccctgaaaa gattatcgag
     7141 ctgtatgcgg agtgcatcag gctctttcac tccatcgaca tatcggattg tccctatacg
     7201 aatagcttag acagccgctt agccgaattg gattacttac tgaataacga tctggccgat
     7261 gtggattgcg aaaactggga agaagacact ccatttaaag atccgcgcga gctgtatgat
     7321 tttttaaaga cggaaaagcc cgaagaggaa cttgtctttt cccacggcga cctgggagac
     7381 agcaacatct ttgtgaaaga tggcaaagta agtggcttta ttgatcttgg gagaagcggc
     7441 agggcggaca agtggtatga cattgccttc tgcgtccggt cgatcaggga ggatatcggg
     7501 gaagaacagt atgtcgagct attttttgac ttactgggga tcaagcctga ttgggagaaa
     7561 ataaaatatt atattttact ggatgaattg ttttagtacc tagatttaga tgtctaaaaa
     7621 gctttaacta caagcttttt agacatctaa tcttttctga agtacatccg caactgtcca
     7681 tactctgatg ttttatatct tttctaaaag ttcgctagat agagttctat attagagatg
     7741 taaagagttt tggtgaagag gtttgtgagt atggctttta taaccagggt gcaatgagaa
     7801 gcactaacag cagctagctt aagaacgcat aggatatact ttttatggaa gtcacagagg
     7861 aggaataaaa tttgaacagg attaacagag taacctctat tcttattcag ctgcaatcaa
     7921 aaaaaataat tcctgccaaa gaaattgcac agcgatttaa tataagctta aggacagttt
     7981 acagagatat ccggacactt gaagaagccg gaataccaat tggatctgag gccggaaaag
     8041 gatattttct tgtagagggc ttcctacttc cgccggtaat gtttacagcg gcggaagtgg
     8101 gtgcattgat tacagcaggg aaatttttaa attgccatgg agatgaatca tttataaagg
     8161 attttgattc agctatgtat aaaatcaaat ctattttgaa gcatggtgaa aaaaactatg
     8221 cacaggagtt ggagaacagt attaacgtgt acagcacatc tggacagaaa aatacattgg
     8281 cggataacgt tattgcagca attcagactg caatctgcaa taaaagggta atatcaattc
     8341 aatatcctgc atcaggaggg caagaaccgg aaagcagaat gatagagcct atatcactgg
     8401 ggttttatga acagaactgg tacttaatcg gttttgcagg ctaagaaatg aatataggaa
     8461 ttttcgtgtg gatcggatta aaagcatttg catagaagaa gagctctgtc aaagccatga
     8521 tggctctttg gaacaaatat taaaacaaat gctttcatat aaaaaactat atgccctaca
     8581 atgccgttgt aaaaattggg gaaaagggat atattgattt tatatctttc tcaaaataaa
     8641 tataaaagcc ctttaaagag ggcttttata tattaatcac aaatcactta tcacaaatca
     8701 caagtgatta atcacaaatc acttgtgat
//
LOCUS       DADGHT010000305         5099 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.guided.140, whole genome shotgun sequence.
ACCESSION   DADGHT010000305 DADGHT010000000
VERSION     DADGHT010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.guided.140"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1825
                     /locus_tag="JX887_003014"
     CDS             <1..1825
                     /locus_tag="JX887_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAX1258910.1"
                     /translation="QISFLVHEKDRIGLIGTNGTGKTSLLNIIAGIDSSDGDRQTVFY
                     PTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRAYEEALIELGENGEDPDVQKR
                     YAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKISTLSGGQKKRVSLAQVLIDEPD
                     LLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRYFLDRVANRIFELSFGKLYEY
                     KGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRAGVQARGTKQQARINRFEDLK
                     ENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQTLLEHLDLLIQSRERLGITG
                     KNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQENEEMAPDKRMIAYLQEAAEE
                     AKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKRRLFLLKLLIQQPNVLLLDEP
                     TNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVADKLLVFQGNGKQELYYGNMSS
                     YLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEWETIEDEIAELEEKISLLQEE
                     MNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEWVED"
     gene            1837..2784
                     /locus_tag="JX887_003015"
     CDS             1837..2784
                     /locus_tag="JX887_003015"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAX1258911.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            2804..3331
                     /locus_tag="JX887_003016"
     CDS             2804..3331
                     /locus_tag="JX887_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAX1258912.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(3394..4047)
                     /locus_tag="JX887_003017"
     CDS             complement(3394..4047)
                     /locus_tag="JX887_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAX1258913.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            4179..5021
                     /locus_tag="JX887_003018"
     CDS             4179..5021
                     /locus_tag="JX887_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAX1258914.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
BASE COUNT         1813 a          895 c         1087 g         1304 t
ORIGIN      
        1 ccagatttct tttttggtcc acgaaaaaga ccgtatcggg ttgattggga cgaacgggac
       61 gggtaaaaca agtctcttaa atattattgc cggtatcgat agcagcgacg gtgatcggca
      121 aacagtgttt tatccaactg attaccgtat tggttatctt tctcaagcag ctgaattttc
      181 cgatgaatta actgttctcc aagcagtctt tcaaggaaac agccccttga tccaaactgt
      241 tcgagcatat gaggaagcat tgatcgaact aggggaaaac ggagaagacc ctgatgtgca
      301 aaaacgttat gctaaagcag aagaacaaat gaataaagaa gatgcttgga ctacagatac
      361 caacgcaaag attattttgc aaaaattagg aatcagtgaa ttagataaaa aaatcagtac
      421 tttatcaggt ggtcagaaaa aacgagttag tctggcgcaa gtgttgattg atgaacccga
      481 tttactatta ctagacgaac caacaaacca tttagattat gaagcgatcg agtggttgga
      541 aaactatttg aaacaatacc gtggcgcact attgatggtt acccacgatc gttattttct
      601 agatagagta gcaaaccgaa tcttcgaact ttcatttgga aaattatacg agtataaagg
      661 aaattatgaa gcttacgtct tagaaaaagc agaacgtgat cgtgtagaag tagaacaaga
      721 agaaaagcgc aagcggcttt ataaacagga attagcttgg atgagggctg gcgtacaggc
      781 acgtggcacc aagcagcaag cacggatcaa ccgtttcgaa gatctaaagg agaacttgta
      841 ccaagtaaac caagaagatg atttagagct gaacctagcg acacaacgtt tagggaaaaa
      901 agtactggaa atcaaagatg gcagttaccg tataaatgac caaacactgc tagaacattt
      961 agatttattg attcaatctc gggaaagact aggtattact ggtaaaaatg gtgcgggaaa
     1021 atcgacattg cttaatattc tagctggcag aattcccctg gatagcggta caatgtctat
     1081 cggtgaaacg gttcatcttg cgtattatac acaagaaaat gaagaaatgg caccagataa
     1141 acggatgatt gcttacttac aagaagctgc tgaagaagca aaaacagcag atggcagtca
     1201 aatcggagta gcagaattac ttgaacgatt tttatttcca agatttatgc atgggacact
     1261 gataggcaaa ctttcaggcg gagaaaaacg ccggttattt ttgttgaaac tgctgattca
     1321 gcaacctaat gttttattat tggatgaacc gaccaatgat ttggacatag caacattgac
     1381 gattttggaa gattatttta gaagttttcc aggtgctgtg atcactgttt cccatgaccg
     1441 ttatttcttg gacaaggtag cagataagtt attagtattc caaggaaacg gaaaacaaga
     1501 actttattac ggaaacatgt ccagttattt actgaagcaa aaagagaccc agcagcctgc
     1561 tgaaaaagcg aaaccaaaaa tacagagcaa ggaacctgct gaaaagaaga aattatctta
     1621 catggaacaa aaagaatggg aaacgattga agatgagatt gcagaacttg aagaaaaaat
     1681 ctcattgctc caagaagaga tgaatcatca aggagataat ttcactcgat tacaagaatt
     1741 gcaaaacgac gtatctgaaa cagaagcaca acttgaagaa aaaatggcac ggtgggaata
     1801 cttgagtgaa tgggtagaag attaggagga aaaaggatgg aacaagcgta tcttgactta
     1861 ggaagaaaat tgttggaaga agggcatcgt aaagaagaca gaacaggcac aggcacatta
     1921 agcttattcg gataccaaat gcggtttgat ctgcaaaaag ggtttccttt gttaacaacg
     1981 aaacgagtac cttttggatt gatcaaaagc gaattgcttt ggtttttaaa aggagatacg
     2041 aatatccgct atctattaca aaataaaaac catatttggg atgaatgggc atttgaacgc
     2101 tacatcaaaa gtccagacta taatggacca gatatgactg attttggcca tagatgtttg
     2161 acagatcctg aattcaatga agaatataaa aagcagagca agcttttttg cgagaagatc
     2221 ctaaccgatg attcctttgc tgaaacatac ggcgatcttg gacacatcta cggctatcaa
     2281 tggcgtcact gggaaacaaa agacggtggc tttatcgatc aaatcaaaca agtgatcgaa
     2341 gcaatcaaaa agactcctga ttctagaaga ttgatcgttt ctgcatggaa tccggaagat
     2401 gttcctagca tggctttgcc tccttgtcat acgatgtttc aattttatgt tcaagaggga
     2461 cggctaagct gccaattgta tcaacgcagt ggggatgtgt ttctaggcgt tccgttcaac
     2521 attgcaagtt atgcgttgct gactcaccta attgcacatg aaacaggttt agcggttggc
     2581 gaatttgttc acacattagg agatgctcat ctttatatca atcatatcga acaaatgaaa
     2641 gaacaattga gccgagaaat acgcgcattt ccgactttag ttttgaatca ggaaaagcag
     2701 tcagtatttg attttgagat ggaagatatc caattagaag gatatgaccc acatccggcg
     2761 atcaaagctc ctatcgctgt ttagaatcag aaaggatgag aaaatgttag ctgcaatttg
     2821 ggcacaggat gaaaacggat tgattggaaa agaagaccgt cttccttggc gtttgccaaa
     2881 tgatctgaaa ttcttcaaac aaatgacaga agcaaataca ctagtgatgg gacgaaaaac
     2941 attcgaaggg atgggtagcc gtccgttgcc gaatcgtcag acgattgttt tgacgagaga
     3001 ttcttcctat aaagcagaag gcgtgcatgt catgcatagt gtggaagacg tgcttgctct
     3061 ggaaaaagaa acagacggta tctttttcat cgctggaggg tcagctgttt atcaagaatt
     3121 tctgccattt tgtacgatat tataccgtac agtcatccat catgtattcg atggagatgc
     3181 ttattttcca cctgttgact ggtctgattg gtcactgatc aatactagtc aaggagaaat
     3241 ggatgaaaaa aatcgttatc cgcatcaatt tgaaacgtat cagcgtaatg agaatcctgt
     3301 aaaaagcggg acaggcgaat tgacgatata aaaaagctat ggatagacta gctgttattt
     3361 agagctgtcc catccatagc tttatttttt ttattaagta aagaataaaa cagagaagta
     3421 cataaaacct gcacctaaca taacaaacaa atgccaaaca acatgcatat agcggataga
     3481 attcaagcta taaaagaatg cgcctatcgt gtaagaaagc ccgcctgcta ccatcaaaat
     3541 aacaccagtc attccaagag agtgataaag aggaacagca gccacgacac agagccaccc
     3601 cataaaaata tagatgatcg tagatacttt tgatactctc tcccgtttat gcaacgtcaa
     3661 cgctttatat ataatgccaa gaatcgcaaa caaccagatt aatacaaata aagtccaacc
     3721 tagccatcct cggatactca gcaaacaaaa aggagtataa cttcctgcaa tcaaaagaaa
     3781 aatcgaacta tgatcgaata cttggaacac cttttttgct tttgtaaaaa tcaatgaatg
     3841 aaacaaagta gacgttaaaa ataaaagaat catcatcgat ccatagatag cataagagac
     3901 aatatggagg gaggaatgca agtgggcacc ttttactaaa agaaccacta gtcccgcgat
     3961 actcaatcca gtcccaattc catgggtgac tgcattaaac acttcattta atatttcata
     4021 cgttcgatta aatttcgttt tttccatgaa aacggctcct ttactaggtg taattaatga
     4081 aaaatcatta tttgtctgtt atactaaaaa tagaaattgt cttacatgta gtttaacatg
     4141 aataaggcat cttgttaaag aaagagagag agaaaataat gacaaatgta aaaatcgtaa
     4201 cagattcttc atgtacgatg gaaaaaaatg tacgcgatgc tttaggcatt cgtgtcatgc
     4261 cgctatccat catgatcgac ggaacagtat atcccgatga tgaccaacta gacggcgaaa
     4321 gatttatgga aatgatggcg aaagcaaaaa atctgcccaa aacaagccaa ccaccaattg
     4381 gagaattcat ctcgatgtat gatgagctag gagaagacgg cagtgaagtg atttcgatcc
     4441 atatgacaaa aggcttgagt ggaacagtag aagcagcaag acaagccagt aatctaacaa
     4501 aaacgaaagt aacggttatc gacagtgata ccactgacca aggattatct tttcaggtaa
     4561 ttcgagcagc tgaattagca aaagaaggta aaacagtaga gaaaatcctt gaagaagtca
     4621 aaaaagtaca agacaataca aaattataca tcggaatatc cacactagat aacttggtaa
     4681 aaggtggaag aatcagccga acaactggtt tgctgtctag tgttttgaac atacgcgtgg
     4741 tgatgaattt cgcccattct gaattaatcc ctgtaactaa ggggcgagga aagaaaacgt
     4801 tcgataaatg gtttaataat ttgaaaaatg aactgaaaga attgccaaat gtgcgacaaa
     4861 tcggtatttc acatgcggat gcaaaagaat tggcgcaaga attcaaagag ggtttgcaag
     4921 aattattccc ggacatgcat atccctgtac tgcatacgaa tccggttatc gctacgcata
     4981 ctggtaaaga cgcgtttgca atcatgtatt atgtagatta gtcgaaaaga ggataagccc
     5041 tcagcctgaa aggcttgcag cttattctct ttttctttat aaaattagga aaataattg
//
LOCUS       DADGHT010000306         4519 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.guided.148, whole genome shotgun sequence.
ACCESSION   DADGHT010000306 DADGHT010000000
VERSION     DADGHT010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.guided.148"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            23..598
                     /locus_tag="JX887_003019"
     CDS             23..598
                     /locus_tag="JX887_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAX1258915.1"
                     /translation="MIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLDKQAGKIAQ
                     QIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKIEQADVIIT
                     GEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIVLSIHLGPI
                     GLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            856..2358
                     /locus_tag="JX887_003020"
     CDS             856..2358
                     /locus_tag="JX887_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAX1258916.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            2425..2952
                     /locus_tag="JX887_003021"
     CDS             2425..2952
                     /locus_tag="JX887_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAX1258917.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            3163..4224
                     /locus_tag="JX887_003022"
     CDS             3163..4224
                     /locus_tag="JX887_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAX1258918.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            4227..>4519
                     /gene="murQ"
                     /locus_tag="JX887_003023"
                     /gene_synonym="yfeU"
     CDS             4227..>4519
                     /gene="murQ"
                     /locus_tag="JX887_003023"
                     /gene_synonym="yfeU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="catalyzes the cleavage of the lactyl ether moiety
                     of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form
                     N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate;
                     involved in MurNAc dissimilation pathway; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAX1258919.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMV"
BASE COUNT         1562 a          770 c         1003 g         1184 t
ORIGIN      
        1 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
       61 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
      121 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
      181 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
      241 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
      301 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
      361 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
      421 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
      481 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
      541 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
      601 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
      661 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
      721 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
      781 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
      841 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
      901 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
      961 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     1021 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     1081 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     1141 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     1201 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     1261 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     1321 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     1381 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     1441 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     1501 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     1561 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     1621 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     1681 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     1741 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     1801 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     1861 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     1921 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     1981 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     2041 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     2101 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     2161 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     2221 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     2281 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     2341 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     2401 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     2461 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     2521 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     2581 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     2641 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     2701 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     2761 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     2821 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     2881 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     2941 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     3001 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     3061 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     3121 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     3181 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     3241 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     3301 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     3361 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     3421 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     3481 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     3541 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     3601 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     3661 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     3721 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     3781 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     3841 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     3901 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     3961 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     4021 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     4081 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     4141 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     4201 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     4261 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     4321 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     4381 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     4441 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     4501 gtgtagaacc ggaaatggt
//
LOCUS       DADGHT010000307         4153 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.guided.156, whole genome shotgun sequence.
ACCESSION   DADGHT010000307 DADGHT010000000
VERSION     DADGHT010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.guided.156"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            124..816
                     /locus_tag="JX887_003024"
     CDS             124..816
                     /locus_tag="JX887_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAX1258920.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1143..1640
                     /gene="dfrG"
                     /locus_tag="JX887_003025"
     CDS             1143..1640
                     /gene="dfrG"
                     /locus_tag="JX887_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAX1258921.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1712..3664)
                     /locus_tag="JX887_003026"
     CDS             complement(1712..3664)
                     /locus_tag="JX887_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAX1258922.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3671..3967)
                     /locus_tag="JX887_003027"
     CDS             complement(3671..3967)
                     /locus_tag="JX887_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAX1258923.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT         1400 a          700 c          688 g         1365 t
ORIGIN      
        1 gattaaatga gtatttgata gtatttatat taaaattaca tatgtaattt aaaaacgctt
       61 gacattgtgt ttgagatcac ttacttttag catgtaaaag tattggatta aggagctatg
      121 caaatgaaaa agaaatttat tactggtggg attgtcgttg catttctatg tctaattggc
      181 tacacaggca cgcggtacgc aaatgaaatt attttgtggg gtggagagac agatattgat
      241 acaatcaatg agaatctgac acagcttgat catacattga cagataaaga gcaagcgatt
      301 acagatctta ccgctcgact agcacaaaaa gaacagacat tgcaagattc aaaggcagat
      361 gtccaagaat accaaacaaa agtaaatgaa ttagaaaacc aaaaaaatca atcggcagca
      421 gaaaaacaaa acttagaaag tcaattagtc agcaaggatg cacaactaca aagcaaacaa
      481 aatgaaatca atgtcaaact agatgagatc aaccaaaaaa atgatgaaat caatcatctg
      541 aatgcagatt ggacagcaag actacaagaa gcacaagcaa aactttcaga attacaaaat
      601 actgtaaatg gtttgaatca acaaatcgca acactgacac aagaaaaaac aaatgtagaa
      661 actcagttaa cagatacaca aaagaaatta gacgaagcaa ctgctgaaaa ctcaagcttg
      721 aaacaatata ttcaaaagtt agaaaaagca aaagatgaag tggaagatac agctgataaa
      781 tctcagcaaa ttgttgaaga acatttgcgt aaataatctt tcttaacaag taaacctaaa
      841 ttagtaaaga agcaacagta atctatacta agtagttcag ttttggagta caaaatgaca
      901 aaatgtactt caaaatggac tacttttttc attttaactt acataccaaa ttacatacaa
      961 aatgatttat aaaatgcaat tgaaaatgat aattgaatga aaatttgtga ttttgtggta
     1021 ttatgataat ataacttata gaaaaaattg cttattcaac taacgggcag gataatgaga
     1081 aaaggttttt tgatagaaat aagaaattag atggtaaatt agttaaaaag gctgtgttat
     1141 aaatgaaagt ttctttgatt gctgcgatgg ataagaatag agtgattggc aaagagaatg
     1201 acattccttg gaggattccc aaggactggg aatatgttaa aaatactaca aagggacatc
     1261 cgataatatt aggtaggaag aaccttgaat caatcggaag agccttacct gacagaagaa
     1321 atattattct gacgagagat aaggggttta cctttaatgg ttgtgaaatt gttcattcaa
     1381 tagaagatgt ttttgagtta tgtaaaaacg aagaagaaat ttttattttc ggaggagaac
     1441 agatttataa tttgtttttc ccttatgttg agaaaatgta catcacaaaa atacatcatg
     1501 aattcgaagg agatactttt tttccagaag tgaattatga ggaatggaat gaggtatttg
     1561 cccaaaaagg gataaagaat gataaaaatc cgtataacta ctattttcat gtatatgaaa
     1621 gaaaaaactt attgagttaa cgggtgcgtt aattgaagaa gaacagtaaa gataaagcac
     1681 aagagcttgg gattactcca agctcttttt gtcatttgaa ataaattata tctttccaat
     1741 caaattgttt atctgtaatc cctaatcttt gagcaggtgt caaaaccttt ttatccgctg
     1801 atttaaaagg gcgacaaaag ttgtagtaag ttcttagaat tgtaatcgca aattgagcat
     1861 acttcggatt gaagttagcg taaatatagc tcttcttatc accacgagct gttgttaatg
     1921 gtctttcaag agatgatata taacgtctta tctgttgaat aaagctattg gtcgaatggt
     1981 cattaacatt taatagcatc tttgcgattt cgtttggttc cagagcagat aaatccgttc
     2041 tacaatcaac tgaataaaat cctttatcct tagtggctaa tggatgtttg atagggttat
     2101 cggcatattt gcgatatctt tctccatctt tactaatagc ctcttcgtgg aattgatgac
     2161 ttgttagtaa ttcagttaga taatgagatg ccaaagtccg tagaaacttt gttttgaatc
     2221 ctctgatatc tccccaatcg agcagttctg cttttgcttg tccgaattct tttaagcatt
     2281 gttttctgct tttcgtcttg ttaacttggc aaataaaatg atgtgcatcg ctcaacctta
     2341 attctttcgt gaatactcta taaaaggcgt ttctaataga gaagtcatca tcactaatca
     2401 ttcgccattc gtcggcatta accatttgtt taattaacca atagtgagca gttgtagtat
     2461 aaggagcatc aacatttaaa ccatcgacaa atctactcct attagtaatt ttccctaatt
     2521 cgtgaagata agcattccta ttttcgctat cgttagcgga tggttcttgt ggataataag
     2581 accaatctaa cctatcattt ttacgactaa aagtattgag atggtcttct ttgaattttc
     2641 ttgtatcttc atttaattca tccattgaaa tattccaatc ataggcaaca tcagaacgga
     2701 acacatatct tgataagacc tcagcagata caactatata cgtttgcata ttaaggtctt
     2761 caaaccccgt atatttcttt gaaccttgtc ctttcttacg gacgttattt aggtagtagt
     2821 gcatcttgtc cgtattaagc cacatctcgt taaatttctt tgtttgaagg ggttgtgtct
     2881 catatcgttc taaaaactcc aaacaacgcc tatacagcca ctccagctta tgatagtagg
     2941 ttccaactcc aattcctaaa atatcacaag tacgactgac tgaaaccctt ccaacaacca
     3001 tcttagcgaa cattggaaga atggtgttct tttgttggtg ataagtagtg gtttcttctc
     3061 tttttggtag aacattagtg aacttcttac acgccttaca ttgatagcgt tgagatttgc
     3121 ccctactttt cccccttttg taaaattgct tcggctcatt gaatggggtt gattcttctt
     3181 ccgagcagcc ttctttatga aattgataat ctggctcaac atcttggatg ctattgattt
     3241 ctataaggcg tttaatttct tcaacaacag accaattaga taaaggggtt actgtacagt
     3301 tttgcgatac acctctgcca ataggattgt cattgcagta cataccttta tgacctttat
     3361 ctttggaact accagtcatt ttatatcgac ttggtttccc ttttacatct ttgaatttgt
     3421 gctgttcttt cccaaaatta caacaaaacg gattgatgca gtaattatat tgaatgggat
     3481 attcagaacc gttccattta aaagacgttg gcaagaacaa cattttgtta taccttgttg
     3541 caaatcgttt tggagttaat aaatcatatt gtttagccct atcttttaat tcttcgtttg
     3601 aaatcggaat tttaacatct acaatttcat cttccttcgt ggctaatctt ttaagcttgg
     3661 tcattgtcta tcaacccact ctatctttga tacccatttt ttcaacaatc cgcttattac
     3721 ttcgcttgtt ggcaatccat tcaataaact tcttatcgtc taaaatgttc aataagaatt
     3781 catccactgc ttcgctttca gtacgctctg catattcagc gtattgctta actatcaccc
     3841 ttacttgctc tgatatttcc caatccacag acttagcgtt cttatttttt ggctcaagaa
     3901 attgcatagg aaaatgcacc cctttttgct tagtaaattg taaccatttt aacacaccaa
     3961 tttgcattcc tacaataatt atttcacgtt cgcattttta tatacatttt aacttacatt
     4021 ttgtggtgta aattaacaac aaacgttgat ttaacaataa aaaacgagta tcaaattcag
     4081 ttgcaatttg atactcattt aggtttacat tttcactttt tgtactccaa aactgaacta
     4141 cttaaatcta tac
//
LOCUS       DADGHT010000308         3284 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.guided.169, whole genome shotgun sequence.
ACCESSION   DADGHT010000308 DADGHT010000000
VERSION     DADGHT010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.guided.169"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..823
                     /gene="rlmN"
                     /locus_tag="JX887_003028"
     CDS             <1..823
                     /gene="rlmN"
                     /locus_tag="JX887_003028"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAX1258924.1"
                     /translation="FELPDKNMIETVLMRQEYGLSVCVTTQVGCNIGCTFCASGLLKK
                     NRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVVMGIGEPFDNYDNVMDFLHIINDAK
                     GLAIGARHITVSTSGLAHKIKEFANNGLQVNLAISLHAPNNEVRTSIMRINRSFPIEK
                     LMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQQLADLLKDKKKLAYVNLIPYNPVS
                     EHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHGTDIDAACGQLRSKQMKKTVAK"
     gene            complement(1016..2119)
                     /locus_tag="JX887_003029"
     CDS             complement(1016..2119)
                     /locus_tag="JX887_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAX1258925.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            2671..3219
                     /gene="aac(6')"
                     /locus_tag="JX887_003030"
     CDS             2671..3219
                     /gene="aac(6')"
                     /locus_tag="JX887_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAX1258926.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         1065 a          574 c          660 g          985 t
ORIGIN      
        1 gtttgaactc cctgataaaa acatgattga gactgtactg atgagacaag aatatggctt
       61 gtcagtttgt gtgacgacac aagtaggatg taatatcggc tgtacgtttt gtgcaagcgg
      121 gctgctcaaa aagaaccgtg atctgactgc tggagaaatt gttgcacaga tcatgatggt
      181 ccaacattat tttgatgagc gcaatcttgg cgaacgcgtt tcacatgtcg ttgtaatggg
      241 gatcggtgag ccatttgata attacgacaa tgtaatggac tttttgcata tcatcaatga
      301 tgccaaagga ttggcaattg gtgctcggca cattacagtt tccactagtg gattagcaca
      361 caaaatcaag gaattcgcta ataacggctt gcaagtcaat ctggctattt ccttgcacgc
      421 gccgaataat gaggtgcgaa catcgatcat gcggatcaac cgaagtttcc caattgagaa
      481 attgatggaa gctgtggatg agtatttaga gaaaacaaac cgtcgaatca cgtttgaata
      541 tatcatgttg aatcaagtaa atgatagacc agagcatgcg caacaattag cagatctatt
      601 aaaagataag aaaaaattag catatgtcaa cttgattcca tataatccag tcagtgaaca
      661 tgatcaatat tctcgcagtc caaaagctga tgtattgaga ttttatgatg tattgaagaa
      721 aaacggcgta aactgtgtga tacgtaaaga acatggtaca gatattgatg cagcttgcgg
      781 acaattgcga agcaagcaaa tgaaaaaaac agttgccaaa taatcgtatc ctactcgttt
      841 tttcaattac cataaaagga gcagttttct taattaagga actgttcaac ttaaataaga
      901 gaaaagattc tatagcgaaa gctataaagc tttttttgac aagaaaaacc ctcatcaagc
      961 aaagaaatgt cctcaatttg atgacagcct gcttgatggg ggttttagca attatttaac
     1021 tgattttctt atatccttgc tggctttctt gtgtagcatg ataagtttct acgtcaagaa
     1081 tggcctgttt aaatttttct cgggtgattt cataaggcac atgtttaata tcatttgttg
     1141 ccatggcttt atctaagatt gcttctaaat cggtcgtgac attgagattc atgtcggtta
     1201 acgatactgg aagttggttc tttttcataa acacatagat tttatcaaac aaatcgaact
     1261 gctgatccat catcaataag gtcagtacac cataactgac agatgctccg tgaaggtatc
     1321 cctccatttt ttctagaaca gtcgtaccgt aatagaatga gtgtgccata gcagaattat
     1381 agttattgtt aactaaaaca gaaaccaatc cggtagtaac aatgatatcc gaaacgactt
     1441 gttcaattgc atatgaggga cgatcgtcgg cactatcttt caatgcttgc gtaccataag
     1501 tcaagagacg atcaatgcac atttttccga tttggattcc taatctatcc gtgtagccta
     1561 gatcatcgcc acgagcagaa aaagtagatt cgacttcttt ggataaagca tcgccaatac
     1621 ctgcccataa gtatttatca ggtgcttcgg caataattgc tgtatcaatg aaggtgtgta
     1681 caggtggttt tgaaggaaag aagagtccgt ccattacgcc ttcttcgtta tagatgacac
     1741 ataccgcagt gacgggcgaa cagttcgaac caatagtggg aaaggtgaag actggtttag
     1801 ctagtttttc accaatgact tttacagtat cgcaagcacg gccaccaccg actgcaaaca
     1861 ggacgtctgc tttttggaca ctttcatgct ggatcaactg ttcaatattt ccataagttg
     1921 aattaccccc gtaccagaga ctggcgacaa cctctatttc ctgtgtcaaa gctactttta
     1981 ttttgttttc tgcctttgaa agtgcagtct tccctccaat cagcactact tttgtcccat
     2041 attctttgac gattccattt gctttttcat acgcatctgt tccaatggta taatttggta
     2101 agaaaacact ttgactcata ttcatttcct tctttcttcg ttgaaacggg ttaaaatttt
     2161 aaagagtgat cgatctgact gcggctgtag atggagtaga ggtgaaccta agacaggata
     2221 agtgatgaat aaggtggcat gaacaccttg aaatcatcaa taagtatcct aaaaacgaac
     2281 aagtacaaaa acattgaaaa cgacaataat gaatttttgt tcctcttagt atttctaccg
     2341 attccctttg cttttttgta attatctaaa aattctaaaa attaagatta ttatatgaaa
     2401 acaggtttta tttgtcaatt cataattggt tttttttaaa gcaaaagata atctatatca
     2461 tgatgaacaa acagagtttt ttcctccaat tgatggcttt cctgatcttt cctattttga
     2521 ataaagtgtt tctgtataat tttttatttt ataagtaaga taaataatga aagaatagag
     2581 atactgattg gtagctaaag atttttgagc gagaacattt cgttttttca aaaggactgt
     2641 tagaataagc aagaacaagg gggaagacgt atgataatca gtgaatttga ccgtaataat
     2701 ccagtattga aagatcagct ttctgattta ctgagactga cttggccgga agaatatgga
     2761 gacagctcgg cagaagaagt agaagaaatg atgaatccag aacgaatcgc ggtagcagcg
     2821 gtagaccaag atgagttagt aggatttatt ggtgcaatcc ctcaatacgg tatcacaggt
     2881 tgggaattgc atccattagt tgtagaaagc tcccgacgaa agaaccaaat aggtactcga
     2941 ttagtcaatt acttagaaaa agaagtagct tccagaggag gaatcacgat ttatttaggt
     3001 acggatgatt tagaccatgg aacaacgtta agtcaaacgg acctgtatga gcatacattt
     3061 gataaagtgg cttccatcca gaaccttcgt gaacatccgt atgaattcta tgaaaaatta
     3121 ggttataaaa tcgtaggtgt cttaccaaat gcaaatggct gggacaaacc ggatatttgg
     3181 atggcaaaaa cgattattcc tcgaccaaat tctcaataat aaaaagaggt tgtgacagaa
     3241 gtaatcagct tcaagaaata agaaggaatt tacgaaaatt actt
//
LOCUS       DADGHT010000309         2772 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.guided.181, whole genome shotgun sequence.
ACCESSION   DADGHT010000309 DADGHT010000000
VERSION     DADGHT010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.guided.181"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            111..194
                     /locus_tag="JX887_003031"
     CDS             111..194
                     /locus_tag="JX887_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAX1258927.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="JX887_003032"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="JX887_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAX1258928.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1319..2182)
                     /locus_tag="JX887_003033"
     CDS             complement(1319..2182)
                     /locus_tag="JX887_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAX1258929.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2184..2456)
                     /locus_tag="JX887_003034"
     CDS             complement(2184..2456)
                     /locus_tag="JX887_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAX1258930.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2473..2682)
                     /locus_tag="JX887_003035"
     CDS             complement(2473..2682)
                     /locus_tag="JX887_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAX1258931.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          851 a          488 c          443 g          990 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccaa aattttgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ccgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta tagatgtaat
      301 cacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 actcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggaatat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttgtaaatt
     1081 tggaaagtta cacgttacta aagggaatgt agataaatta ttaggtatag ggcacctcta
     1141 ataactacca attaattcac ctcaaaatga aattagaaaa aaacagcgaa atttttaaat
     1201 ctatttctta tcgatacaaa ttcctcgtag gcgctcggga ccccaacatg aggaaatgtt
     1261 tttataaaaa aagagtagtt accgtttttt ggtaactact cttttccttt tttaaggttt
     1321 aaatacctgg aagtttaggt gttttgggta ttggtggtgt aggtagctgc aagctttcca
     1381 ttttttgttg aattgcttta aattcagggg tttcttggtg ttgattttga accatttttt
     1441 gctctattct ctccaaagtc ggttgaattt ctttccctga tactttacga tttaattctc
     1501 tttctaaggt ctctttcgga ctaatggaag gcgtttctaa gcttgaatag agtttcactc
     1561 cttctctatt gtaaagcctt atatcgctaa ataagcccgt tttatgaagg gtttctaaat
     1621 tggtcggtaa gtttttgaca acaatatcat gcgcttgttt tggtgttgcc ctagctgtca
     1681 ttggatcatc tgcatacatg gtttcatatc gttcaatcgt tcctaagtat gattcaattt
     1741 tcggtactgc catgacgtat atttttgttt cataaccttt agattgaagc attgtggctg
     1801 tttgaatggg aacgtctgtt gttcgtcctg ttccttcaat cactaaatta tagccttgat
     1861 cgcttaaacg gctaataagt gcttctgtca tgcgattcga ataaggggta acgtgtttta
     1921 ctacgtcttt ttcatagagt ttcactaatt cgtcaaaatt tgggtgctgt tgtttaaagg
     1981 tatcattatc aatgacaata acattccctt gtgtttcttc aaaaattgct gatcgcaaac
     2041 tggttttccc tgaccctggt tgcccaccaa gtaaaaaagc ggttggcgat tcaaccgcta
     2101 gtctattttt agttagtcgt tcaacattct tttctaaacg atcttcaaat tgcttttcgg
     2161 tgaagtcagt aatattcgcc atgttaagcc actttctctt tattcaaaat ttgttttgaa
     2221 tattgattca ttgaccgcca atactcatga atagcttgta attcttcaaa tggttgttga
     2281 aataaatcaa cttcttgtgc cacttctaat tgatttaaaa gattcacttc tagtaaacga
     2341 gtatttttag tatctagttc atgattcaaa acataattta atacccgatt ataaacactt
     2401 gccgataact cattaatgat ttcaatttca aatgtttttt catacgtaac tgccatttca
     2461 ttttcactcc ttttaaagtt tgtcaggtaa atatttccgt atatattctt ctaaggcttg
     2521 atccataact tcttttacgt ttccgccatt ctttgctgtt tcgattttta tgatatggtg
     2581 caagtcggca cgaacacgaa ccgtcttatc ccccattata tctttttttg cgctgattgg
     2641 cgtatcattt cgttttgctt tctgtgcgcc taaatttccc acgatcgctc acttctttct
     2701 atttcttctt actatttatt ttatcatcac ctatcacaaa tcacaagtga tttgtgatta
     2761 atcacttgtg at
//
LOCUS       DADGHT010000310         2285 bp    DNA     linear   BCT 26-FEB-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate VE1497
            SAMN17922618-rid11628673.guided.194, whole genome shotgun sequence.
ACCESSION   DADGHT010000310 DADGHT010000000
VERSION     DADGHT010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN17922618
            Sequence Read Archive: SRR13717249
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (19-FEB-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 19-FEB-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000968382.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000968382.1
            Genome Coverage       :: 42x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 02/19/2021 20:28:10
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,038
            CDSs (total)                      :: 2,975
            Genes (coding)                    :: 2,910
            CDSs (with protein)               :: 2,910
            Genes (RNA)                       :: 63
            rRNAs                             :: 2, 2 (16S, 23S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 65
            CDSs (without protein)            :: 65
            Pseudo Genes (ambiguous residues) :: 0 of 65
            Pseudo Genes (frameshifted)       :: 34 of 65
            Pseudo Genes (incomplete)         :: 27 of 65
            Pseudo Genes (internal stop)      :: 12 of 65
            Pseudo Genes (multiple problems)  :: 7 of 65
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN17922618-rid11628673.guided.194"
                     /isolate="VE1497"
                     /isolation_source="Rectal screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2019-03-17"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..208
                     /locus_tag="JX887_003036"
     CDS             <1..208
                     /locus_tag="JX887_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAX1258932.1"
                     /translation="AAMQFMLVARDHGYETNPIGGVEADQLAEAFGLDKDRYVPVIIL
                     SIGKAVEEGYESVRLAPEKITTFE"
     gene            562..2040
                     /gene="msr"
                     /locus_tag="JX887_003037"
     CDS             562..2040
                     /gene="msr"
                     /locus_tag="JX887_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAX1258933.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            2087..>2285
                     /locus_tag="JX887_003038"
     CDS             2087..>2285
                     /locus_tag="JX887_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAX1258934.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIA"
BASE COUNT          774 a          367 c          496 g          648 t
ORIGIN      
        1 agcggctatg caattcatgt tagttgcgcg tgatcatggc tatgaaacaa atccaattgg
       61 tggagtcgaa gcagatcagt tggcagaggc atttggtttg gataaagacc gttatgttcc
      121 agttattatt ttatcaatag gaaaagcggt agaagaaggt tacgagtctg ttcgtttagc
      181 accagaaaag atcactacgt tcgaataaaa ggttttcagt tactattcag tagctattgc
      241 tttttttgaa tcgtgtgtgg taacctaata aaaaaggagg tcggaaaaat gactgcatcg
      301 atgaaattac gtttcgaact tttgaataac aactaaataa attcaaaaga catgtataaa
      361 caacaatttc atggatggag tatgtccatt ttttcgaacg acagtagaat aggtgaaagc
      421 tatgacagat ttggtgattt agtcatagtt atttcgttca gagtaggaaa agatgtgatg
      481 cagttttttt gcaaacagat ttttctgctc ttttttagta tcgataattg ttgttttaca
      541 tgaaatagga gtgtaaaaca tatggaaaat ttagcagtaa atataacaaa tctacaagtc
      601 agctttggca accagctaga actatctatt gattctcttc gtgtctatca gcaagatcgt
      661 atagggatca taggagaaaa tggtgtcggt aaatcgactt tgctcaaact aatagccggt
      721 gaactttttc ccgatcatgg gaaaatccaa acagagatca ccttcaacta cctgcctcaa
      781 ttaacctatc tcgctgaagc aaaggaccta aatttggaat tagccagtca tttccagtta
      841 agactggaag aaacttcaga gcggaaatgg agcggagggg aagaacgaaa gatcgagttg
      901 atacgtcttc tttcttctta tgaacaaggg atgcttctag acgagccaac aacccatcta
      961 gatagaaaaa gtattgatcg actgattgaa gagcttcgtt attattatgg tacgctggtt
     1021 tttgttagtc atgatcgcta ttttctagat gagctagcat cgaaaatctg ggaagtaaaa
     1081 gacggagaaa tccgagagtt ttcggggaat tatagtgcct atctcactca aaaggaattg
     1141 gagaaaaaga ctcagctacg agaagcagag tcgatcatga aagagaaaaa acgattggaa
     1201 aaatcgatcc aagaaaagaa aaaacaagcg gaaaagttgg aaaaagtgtc cagtaaaaag
     1261 aaaaagcaac aaatcagacc ggatcggttg tcttcctcta aacaaaaaga cagtgtacaa
     1321 aaagccatcc aaaagaatgc gaaaacatta gagagaagac tccaaaaaat aggagaaaca
     1381 accaagccgc agcagatgaa acaaatccgt tttccagtac caaaatctct tgaactccac
     1441 agccgctatc ccatcatggg acaaaatgtc caattggaaa gaagtgggag aacattactg
     1501 gtaaatggtg attttcagtt ttctttaggt aaaaaaatcg cgattgtcgg tgaaaatggt
     1561 tcaggtaaga caaccttatt agaacatatc cgcaaacaag gagaaggaat ccttctctct
     1621 ccgaaagtaa gctttcaagt atatcagcaa aagggttatc aaatgacatc tgaagaatcc
     1681 atcattcgtt ttgtcatgag acaaacagag ttttcagaat cgcttgtccg tagtttgctg
     1741 aatcacttag ggtttgctca ggaaactttg acgaaaccgt tatgtacatt aagtggggga
     1801 gaagcgaccc gtctgacgat tgctttgctt tttactaagc caagtaatgt gttgctgtta
     1861 gatgaaccga ctaattttat tgatatggca acgatcgaag ctttagagaa gctaatgcaa
     1921 atatatccgg gaacgatttt gtttacttct catgattctt actttgtcga gcgtacggct
     1981 gatgaagttt atgaaataaa agggcagaaa ataaaaaaag tacttacgag aaatttttaa
     2041 atgtgctacg atgattttcg tgacaaattt aaaggagtgg tacagattgc ctacaaataa
     2101 aaaagaagga ataattttta caacaatgat gtgttttttg atggtcttgg ggatgagcgc
     2161 gtataattta tggctgcatc aagatcttca tttatcaagt ttgttgattg gtctagtgcc
     2221 tggattcgtg gtggctttca ttttggatgt cttcatcatc ggtgtgctgg cgaaaaaaat
     2281 tgcct
//
